LOCUS       DAFENC010000001       128067 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.001, whole genome shotgun sequence.
ACCESSION   DAFENC010000001
VERSION     DAFENC010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 128067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 128067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..128067
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.001"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(466..1962)
                     /gene="lysS"
                     /locus_tag="LP493_000001"
     CDS             complement(466..1962)
                     /gene="lysS"
                     /locus_tag="LP493_000001"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBL2132188.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(2073..3077)
                     /gene="dusB"
                     /locus_tag="LP493_000002"
     CDS             complement(2073..3077)
                     /gene="dusB"
                     /locus_tag="LP493_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HBL2132189.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(3078..3965)
                     /gene="hslO"
                     /locus_tag="LP493_000003"
     CDS             complement(3078..3965)
                     /gene="hslO"
                     /locus_tag="LP493_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HBL2132190.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(4182..6293)
                     /gene="ftsH"
                     /locus_tag="LP493_000004"
     CDS             complement(4182..6293)
                     /gene="ftsH"
                     /locus_tag="LP493_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBL2132191.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(6383..6928)
                     /gene="hpt"
                     /locus_tag="LP493_000005"
     CDS             complement(6383..6928)
                     /gene="hpt"
                     /locus_tag="LP493_000005"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBL2132192.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6928..8373)
                     /gene="tilS"
                     /locus_tag="LP493_000006"
     CDS             complement(6928..8373)
                     /gene="tilS"
                     /locus_tag="LP493_000006"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HBL2132193.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8493..8963)
                     /locus_tag="LP493_000007"
     CDS             complement(8493..8963)
                     /locus_tag="LP493_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HBL2132194.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(9009..9434)
                     /locus_tag="LP493_000008"
     CDS             complement(9009..9434)
                     /locus_tag="LP493_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HBL2132195.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9501..9770)
                     /locus_tag="LP493_000009"
     CDS             complement(9501..9770)
                     /locus_tag="LP493_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HBL2132196.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9781..11376)
                     /locus_tag="LP493_000010"
     CDS             complement(9781..11376)
                     /locus_tag="LP493_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBL2132197.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(11391..14912)
                     /gene="mfd"
                     /locus_tag="LP493_000011"
     CDS             complement(11391..14912)
                     /gene="mfd"
                     /locus_tag="LP493_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HBL2132198.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14929..15489)
                     /locus_tag="LP493_000012"
     CDS             complement(14929..15489)
                     /locus_tag="LP493_000012"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBL2132199.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15842..16816
                     /locus_tag="LP493_000013"
     CDS             15842..16816
                     /locus_tag="LP493_000013"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBL2132200.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16986..18386
                     /locus_tag="LP493_000014"
     CDS             16986..18386
                     /locus_tag="LP493_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HBL2132201.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18464..19186)
                     /locus_tag="LP493_000015"
     CDS             complement(18464..19186)
                     /locus_tag="LP493_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2132202.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(19265..19771)
                     /locus_tag="LP493_000016"
     CDS             complement(19265..19771)
                     /locus_tag="LP493_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBL2132203.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSINHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19894..21693
                     /locus_tag="LP493_000017"
     CDS             19894..21693
                     /locus_tag="LP493_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HBL2132204.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21761..23335)
                     /locus_tag="LP493_000018"
     CDS             complement(21761..23335)
                     /locus_tag="LP493_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBL2132205.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23590..24099)
                     /gene="mreD"
                     /locus_tag="LP493_000019"
     CDS             complement(23590..24099)
                     /gene="mreD"
                     /locus_tag="LP493_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HBL2132206.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(24103..24957)
                     /gene="mreC"
                     /locus_tag="LP493_000020"
     CDS             complement(24103..24957)
                     /gene="mreC"
                     /locus_tag="LP493_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HBL2132207.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(25112..25750)
                     /locus_tag="LP493_000021"
     CDS             complement(25112..25750)
                     /locus_tag="LP493_000021"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HBL2132208.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25751..26401)
                     /locus_tag="LP493_000022"
     CDS             complement(25751..26401)
                     /locus_tag="LP493_000022"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBL2132209.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGRFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(26414..27313)
                     /gene="rsgA"
                     /locus_tag="LP493_000023"
     CDS             complement(26414..27313)
                     /gene="rsgA"
                     /locus_tag="LP493_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBL2132210.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27478..29547)
                     /gene="pknB"
                     /locus_tag="LP493_000024"
     CDS             complement(27478..29547)
                     /gene="pknB"
                     /locus_tag="LP493_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HBL2132211.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29544..30284)
                     /locus_tag="LP493_000025"
     CDS             complement(29544..30284)
                     /locus_tag="LP493_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HBL2132212.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(30297..31655)
                     /gene="rsmB"
                     /locus_tag="LP493_000026"
     CDS             complement(30297..31655)
                     /gene="rsmB"
                     /locus_tag="LP493_000026"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HBL2132213.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKMLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31655..32593)
                     /locus_tag="LP493_000027"
     CDS             complement(31655..32593)
                     /locus_tag="LP493_000027"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HBL2132214.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKKAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32586..33077)
                     /gene="def"
                     /locus_tag="LP493_000028"
     CDS             complement(32586..33077)
                     /gene="def"
                     /locus_tag="LP493_000028"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBL2132215.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(33092..35500)
                     /gene="priA"
                     /locus_tag="LP493_000029"
     CDS             complement(33092..35500)
                     /gene="priA"
                     /locus_tag="LP493_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HBL2132216.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35753..36058)
                     /locus_tag="LP493_000030"
     CDS             complement(35753..36058)
                     /locus_tag="LP493_000030"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBL2132217.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(36063..36677)
                     /gene="gmk"
                     /locus_tag="LP493_000031"
     CDS             complement(36063..36677)
                     /gene="gmk"
                     /locus_tag="LP493_000031"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBL2132218.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEKRMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(37164..37448)
                     /locus_tag="LP493_000032"
     CDS             complement(37164..37448)
                     /locus_tag="LP493_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132219.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(37466..38356)
                     /locus_tag="LP493_000033"
     CDS             complement(37466..38356)
                     /locus_tag="LP493_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HBL2132220.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFVLDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(38376..38594)
                     /locus_tag="LP493_000034"
     CDS             complement(38376..38594)
                     /locus_tag="LP493_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HBL2132221.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(38564..40264)
                     /locus_tag="LP493_000035"
     CDS             complement(38564..40264)
                     /locus_tag="LP493_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBL2132222.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            40531..41304
                     /locus_tag="LP493_000036"
     CDS             40531..41304
                     /locus_tag="LP493_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132223.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(41385..41954)
                     /gene="thiT"
                     /locus_tag="LP493_000037"
     CDS             complement(41385..41954)
                     /gene="thiT"
                     /locus_tag="LP493_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HBL2132224.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(42020..42122)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(42128..43099)
                     /locus_tag="LP493_000038"
     CDS             complement(42128..43099)
                     /locus_tag="LP493_000038"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBL2132225.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(43193..44566)
                     /gene="glmU"
                     /locus_tag="LP493_000039"
     CDS             complement(43193..44566)
                     /gene="glmU"
                     /locus_tag="LP493_000039"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HBL2132226.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(45069..45887)
                     /gene="purR"
                     /locus_tag="LP493_000040"
     CDS             complement(45069..45887)
                     /gene="purR"
                     /locus_tag="LP493_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HBL2132227.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(46054..46878)
                     /locus_tag="LP493_000041"
     CDS             complement(46054..46878)
                     /locus_tag="LP493_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBL2132228.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(46851..47531)
                     /locus_tag="LP493_000042"
     CDS             complement(46851..47531)
                     /locus_tag="LP493_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBL2132229.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(47554..48492)
                     /locus_tag="LP493_000043"
     CDS             complement(47554..48492)
                     /locus_tag="LP493_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HBL2132230.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(48737..49600)
                     /locus_tag="LP493_000044"
     CDS             complement(48737..49600)
                     /locus_tag="LP493_000044"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HBL2132231.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            complement(49742..52315)
                     /gene="mprF"
                     /locus_tag="LP493_000045"
     CDS             complement(49742..52315)
                     /gene="mprF"
                     /locus_tag="LP493_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBL2132232.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFSEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            52456..53262
                     /gene="proC"
                     /locus_tag="LP493_000046"
     CDS             52456..53262
                     /gene="proC"
                     /locus_tag="LP493_000046"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBL2132233.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(53341..54897)
                     /gene="rny"
                     /locus_tag="LP493_000047"
     CDS             complement(53341..54897)
                     /gene="rny"
                     /locus_tag="LP493_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HBL2132234.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(55308..56357)
                     /gene="recA"
                     /locus_tag="LP493_000048"
     CDS             complement(55308..56357)
                     /gene="recA"
                     /locus_tag="LP493_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HBL2132235.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(56466..57707)
                     /locus_tag="LP493_000049"
     CDS             complement(56466..57707)
                     /locus_tag="LP493_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HBL2132236.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(57947..58525)
                     /gene="pgsA"
                     /locus_tag="LP493_000050"
     CDS             complement(57947..58525)
                     /gene="pgsA"
                     /locus_tag="LP493_000050"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HBL2132237.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(58734..59657)
                     /locus_tag="LP493_000051"
     CDS             complement(58734..59657)
                     /locus_tag="LP493_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2132238.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(60396..61682)
                     /locus_tag="LP493_000052"
     CDS             complement(60396..61682)
                     /locus_tag="LP493_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBL2132239.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(61675..62943)
                     /locus_tag="LP493_000053"
     CDS             complement(61675..62943)
                     /locus_tag="LP493_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBL2132240.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            63195..63656
                     /gene="mscL"
                     /locus_tag="LP493_000054"
     CDS             63195..63656
                     /gene="mscL"
                     /locus_tag="LP493_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HBL2132241.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(63715..64161)
                     /locus_tag="LP493_000055"
     CDS             complement(63715..64161)
                     /locus_tag="LP493_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2132242.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(64254..64499)
                     /locus_tag="LP493_000056"
     CDS             complement(64254..64499)
                     /locus_tag="LP493_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HBL2132243.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(64614..65192)
                     /locus_tag="LP493_000057"
     CDS             complement(64614..65192)
                     /locus_tag="LP493_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBL2132244.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(65269..65799)
                     /locus_tag="LP493_000058"
     CDS             complement(65269..65799)
                     /locus_tag="LP493_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HBL2132245.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(65803..66663)
                     /gene="rlmB"
                     /locus_tag="LP493_000059"
     CDS             complement(65803..66663)
                     /gene="rlmB"
                     /locus_tag="LP493_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HBL2132246.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(66656..67051)
                     /locus_tag="LP493_000060"
     CDS             complement(66656..67051)
                     /locus_tag="LP493_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HBL2132247.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(67048..68460)
                     /locus_tag="LP493_000061"
     CDS             complement(67048..68460)
                     /locus_tag="LP493_000061"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HBL2132248.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWVKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(68457..68993)
                     /gene="cysE"
                     /locus_tag="LP493_000062"
     CDS             complement(68457..68993)
                     /gene="cysE"
                     /locus_tag="LP493_000062"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HBL2132249.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(69079..69318)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(69315..70775)
                     /locus_tag="LP493_000063"
     CDS             complement(69315..70775)
                     /locus_tag="LP493_000063"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HBL2132250.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(70945..72102)
                     /locus_tag="LP493_000064"
     CDS             complement(70945..72102)
                     /locus_tag="LP493_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HBL2132251.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(72136..73506)
                     /gene="radA"
                     /locus_tag="LP493_000065"
     CDS             complement(72136..73506)
                     /gene="radA"
                     /locus_tag="LP493_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HBL2132252.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(73569..74096)
                     /locus_tag="LP493_000066"
     CDS             complement(73569..74096)
                     /locus_tag="LP493_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HBL2132253.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            74326..75132
                     /gene="proB"
                     /locus_tag="LP493_000067"
     CDS             74326..75132
                     /gene="proB"
                     /locus_tag="LP493_000067"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HBL2132254.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            75129..76376
                     /locus_tag="LP493_000068"
     CDS             75129..76376
                     /locus_tag="LP493_000068"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HBL2132255.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            76452..76796
                     /locus_tag="LP493_000069"
     CDS             76452..76796
                     /locus_tag="LP493_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132256.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(76913..77239)
                     /locus_tag="LP493_000070"
     CDS             complement(76913..77239)
                     /locus_tag="LP493_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132257.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(77854..79056)
                     /locus_tag="LP493_000071"
     CDS             complement(77854..79056)
                     /locus_tag="LP493_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2132258.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            79173..79688
                     /locus_tag="LP493_000072"
     CDS             79173..79688
                     /locus_tag="LP493_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBL2132259.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(79887..80333)
                     /locus_tag="LP493_000073"
     CDS             complement(79887..80333)
                     /locus_tag="LP493_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBL2132260.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(80380..81858)
                     /gene="msr(C)"
                     /locus_tag="LP493_000074"
     CDS             complement(80380..81858)
                     /gene="msr(C)"
                     /locus_tag="LP493_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBL2132261.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(82212..82841)
                     /locus_tag="LP493_000075"
     CDS             complement(82212..82841)
                     /locus_tag="LP493_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBL2132262.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(82825..83289)
                     /locus_tag="LP493_000076"
     CDS             complement(82825..83289)
                     /locus_tag="LP493_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL2132263.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(83776..85044)
                     /locus_tag="LP493_000077"
     CDS             complement(83776..85044)
                     /locus_tag="LP493_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBL2132264.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(85275..86012)
                     /locus_tag="LP493_000078"
     CDS             complement(85275..86012)
                     /locus_tag="LP493_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL2132265.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(86079..86648)
                     /locus_tag="LP493_000079"
     CDS             complement(86079..86648)
                     /locus_tag="LP493_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBL2132266.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            86776..87648
                     /locus_tag="LP493_000080"
     CDS             86776..87648
                     /locus_tag="LP493_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL2132267.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            87990..88862
                     /locus_tag="LP493_000081"
     CDS             87990..88862
                     /locus_tag="LP493_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL2132268.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            88859..90817
                     /locus_tag="LP493_000082"
     CDS             88859..90817
                     /locus_tag="LP493_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL2132269.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(91149..92000)
                     /locus_tag="LP493_000083"
     CDS             complement(91149..92000)
                     /locus_tag="LP493_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL2132270.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            92123..92590
                     /locus_tag="LP493_000084"
     CDS             92123..92590
                     /locus_tag="LP493_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBL2132271.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(92853..93335)
                     /locus_tag="LP493_000085"
     CDS             complement(92853..93335)
                     /locus_tag="LP493_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBL2132272.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(93435..94298)
                     /locus_tag="LP493_000086"
     CDS             complement(93435..94298)
                     /locus_tag="LP493_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBL2132273.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            94896..95771
                     /locus_tag="LP493_000087"
     CDS             94896..95771
                     /locus_tag="LP493_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132274.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(95916..96068)
                     /locus_tag="LP493_000088"
                     /pseudo
     CDS             complement(95916..96068)
                     /locus_tag="LP493_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(96336..97667)
                     /locus_tag="LP493_000089"
     CDS             complement(96336..97667)
                     /locus_tag="LP493_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2132275.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSFIIIQLF
                     NMDINKLITTIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFLIQN
                     MQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKDFAKLS
                     VTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQIPWT
                     TPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
     gene            complement(97816..98529)
                     /locus_tag="LP493_000090"
     CDS             complement(97816..98529)
                     /locus_tag="LP493_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2132276.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            98704..100128
                     /locus_tag="LP493_000091"
     CDS             98704..100128
                     /locus_tag="LP493_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL2132277.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            100427..101134
                     /locus_tag="LP493_000092"
     CDS             100427..101134
                     /locus_tag="LP493_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBL2132278.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            101121..101444
                     /locus_tag="LP493_000093"
     CDS             101121..101444
                     /locus_tag="LP493_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBL2132279.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(101533..102570)
                     /locus_tag="LP493_000094"
     CDS             complement(101533..102570)
                     /locus_tag="LP493_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HBL2132280.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(102891..103874)
                     /locus_tag="LP493_000095"
     CDS             complement(102891..103874)
                     /locus_tag="LP493_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HBL2132281.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(104289..105059)
                     /locus_tag="LP493_000096"
     CDS             complement(104289..105059)
                     /locus_tag="LP493_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2132282.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMIFGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(105052..105987)
                     /locus_tag="LP493_000097"
     CDS             complement(105052..105987)
                     /locus_tag="LP493_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2132283.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(106303..107952)
                     /locus_tag="LP493_000098"
     CDS             complement(106303..107952)
                     /locus_tag="LP493_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBL2132284.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(108069..110672)
                     /locus_tag="LP493_000099"
     CDS             complement(108069..110672)
                     /locus_tag="LP493_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBL2132285.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(110684..111733)
                     /locus_tag="LP493_000100"
     CDS             complement(110684..111733)
                     /locus_tag="LP493_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBL2132286.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            complement(111759..112073)
                     /locus_tag="LP493_000101"
     CDS             complement(111759..112073)
                     /locus_tag="LP493_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBL2132287.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(112089..112535)
                     /locus_tag="LP493_000102"
     CDS             complement(112089..112535)
                     /locus_tag="LP493_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL2132288.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
     gene            complement(112536..114458)
                     /locus_tag="LP493_000103"
     CDS             complement(112536..114458)
                     /locus_tag="LP493_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBL2132289.1"
                     /translation="MGIEFSERQMKILYFLIENEHTTYKELSEQLYVSTKTISKDILI
                     LKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKINIADSPEDRLTYVFAKLLN
                     TNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLVSDRNGVRIKADEKSKRRL
                     MSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDILKKVAELLNRYMNKTQLK
                     FTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNTLILIKMIEKAFSIIVPID
                     EQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVRIKLNEFYPDEELINNLVL
                     HLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEEIEERFCIHFNEDEIAYVT
                     LHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFADMVEIEDVLSINELQDRK
                     VTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQLNEQTEDAFLNLLDKRFCF
                     FTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKLSSTAMNDFAMPHIEVDFI
                     KKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKIYETFNEIASNHELLANLK
                     TSSSFEKLVYILKEGL"
     gene            complement(114670..115566)
                     /locus_tag="LP493_000104"
     CDS             complement(114670..115566)
                     /locus_tag="LP493_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL2132290.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(115559..116239)
                     /locus_tag="LP493_000105"
     CDS             complement(115559..116239)
                     /locus_tag="LP493_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2132291.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(116240..117022)
                     /locus_tag="LP493_000106"
     CDS             complement(116240..117022)
                     /locus_tag="LP493_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2132292.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(117015..117932)
                     /locus_tag="LP493_000107"
     CDS             complement(117015..117932)
                     /locus_tag="LP493_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2132293.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(118096..118419)
                     /locus_tag="LP493_000108"
     CDS             complement(118096..118419)
                     /locus_tag="LP493_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132294.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWKTTQPRLRDSLIFLGGSLAIVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEK
                     KESGN"
     gene            119207..122434
                     /gene="fss3"
                     /locus_tag="LP493_000109"
     CDS             119207..122434
                     /gene="fss3"
                     /locus_tag="LP493_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HBL2132295.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYCQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            122547..122861
                     /locus_tag="LP493_000110"
     CDS             122547..122861
                     /locus_tag="LP493_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL2132296.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            122874..123248
                     /locus_tag="LP493_000111"
     CDS             122874..123248
                     /locus_tag="LP493_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL2132297.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            123258..123593
                     /locus_tag="LP493_000112"
     CDS             123258..123593
                     /locus_tag="LP493_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HBL2132298.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            123676..125016
                     /locus_tag="LP493_000113"
     CDS             123676..125016
                     /locus_tag="LP493_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBL2132299.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            125094..125768
                     /locus_tag="LP493_000114"
     CDS             125094..125768
                     /locus_tag="LP493_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBL2132300.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            125761..125925
                     /locus_tag="LP493_000115"
     CDS             125761..125925
                     /locus_tag="LP493_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132301.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            126001..127143
                     /gene="dcm"
                     /locus_tag="LP493_000116"
                     /pseudo
     CDS             126001..127143
                     /gene="dcm"
                     /locus_tag="LP493_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            127133..127423
                     /locus_tag="LP493_000117"
     CDS             127133..127423
                     /locus_tag="LP493_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132302.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            127682..>128067
                     /locus_tag="LP493_000118"
     CDS             127682..>128067
                     /locus_tag="LP493_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2132303.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGV"
BASE COUNT        36834 a        26829 c        23006 g        41398 t
ORIGIN      
        1 attgtcaact cttttttaaa agtttttttc gatttcgttt ttcgaaatct ttcggcaact
       61 catttatcat aacttatcgt ttgttatttg tcaagaactt ttttgaagtt tttttcgata
      121 gaatcaagct tcgcaagtgg ttctttttta acgactcagt tatcttatca tgtcgttagt
      181 aacatgtcaa taactttttt gttatgtttt tgaataaata ttttcttctg tcttttggac
      241 aagtaataat ataccaacta aatttagctt ggtcaacgaa ttttttgtat tttttcaagt
      301 ttttttcaat aaacgattat tcataacttt tctttcttta tcgttcgttt tcgtcttctt
      361 taatgtctag aatagtcggc attagctttt gaactttcgt tattatttat tcctttctac
      421 acagcaaaag ctgcctaagg aattccttag acagctttta ttcgattatc tcattgttgg
      481 gaatagcaaa acatcccgaa ttgattgtgc atcagttagc aacattacta atctgtcgat
      541 cccgatgcct agaccaccag ttggcggcat accgtattct aaggcttcca agaagtcttc
      601 gtctacaccg tgagcttcgt catttcctag ttcacgttct ttttcttgcg cttcgaatct
      661 ttctctttga tcaattggat cgttcagttc tgtaaaggca ttagcaaatt cgcgccccac
      721 tatgaatagt tcgaatcgat ctgtgaatcg aggatcttct ggatttttct tcgctaaagg
      781 cgaaacttcg actggatgtc cgtatacaaa cgtcggttgt gtcaatgttt cttcaacaaa
      841 tgtttcaaag aattcattga taacatgtcc gacacccata gcttcggtta cttctacatt
      901 gtgtttttcg gctaaagcta atgcttcttc caatgtcatt tcttgccaga agtctacacc
      961 agtttgttct ttgattgcat ctaccatatg gatgcgttta aagtcacttt ctaagtcgac
     1021 agcttgtcca tcatatgtga tttttgctgt tcctagtact ttttcagctg cgttacggat
     1081 aataccttct gtcagattca ttacatcatt gaaatcagta tatgctgtgt atgcttctaa
     1141 catcgtaaat tctggattat gtgtagtatc aattccttca ttacggaaaa cgcggccgat
     1201 ttcataaact ttttccattc cgccaacaat tagtcgtttt aaatgaagtt ctagcgcaat
     1261 acgcaaatat aaatcaatgt ccagtgcatt atgatgcgtg ataaatgggc gtgcggcagc
     1321 tccacctgcc tcattgtgca atactggtgt ttctacttca atatagccat tgccatctaa
     1381 atagcgacgg atttcgctga taatttggct tcgtttcata aatcggtcaa agctttcgcg
     1441 attactgatt aaatccaagt agcgttgtct gtagcgttgt tcaatattcg ttaagccatg
     1501 gtatttatct ggcagtggac gaagtgcttt tgacaaaatc gtgatttctg aagctttgat
     1561 agaaacttcg cctgtgtctg ttttcatgat ttgtccagtt acaccaaaga aatctccaag
     1621 gtctgcatgt ttgaatactt cataggcctc atcacctact tggtcttttc ttacataaat
     1681 ttgaatttgg ccttcacgat cttgtagatg cgcaaatcca gctttccctt ttcctcggcg
     1741 agtcatcata cgaccagcta cactagcggt caatcccatt tctgctagtt cttcttttgt
     1801 tcttggatca aatagttcat gcaattcttc tgagttgtgc gtgcgttcaa atcgttttcc
     1861 aaatggatcg attccatctt cacgcaattg ttccattttt tgacgacgta caagcatttg
     1921 atcatttaaa tcttctactt gatgttgttg ttcctgtgtc acaaaagttc ctccattctc
     1981 atgttaatct ctttcctata atgccaatga aacacaaaaa aagcaagccg aacttggaat
     2041 ttcggcttga aaattcacga aaaacttaga aatcacaacg tttgtttcaa tagtactttt
     2101 tccgcttttt ctacaaattg atccagcagg tcattgattt cttgctgttt ttctgtctga
     2161 ttgattgcta ctttcacttt cgctgctcga ggaatccctt ttaaataata agccgcatgt
     2221 gttctgaatt ctctacaagc tactttttct cctttgagat ctgctaagcg ttgtaaatga
     2281 agtttagctg tagcaatttt ttcggctggt gttggttcag gaatcagttc ccctgtttcg
     2341 agataatgct gtgtgcggtg aatcatccat ggattgccca gcgctgcacg accaatcatc
     2401 acaccgtctg caccgacata gtcaagcatc cattttgcat cttctggcgt tttgacatcc
     2461 ccgttcccca taaatggaat cgtcaaatgt tttttcactt ctttcaatac ttcccagtcc
     2521 gcttttcctt catacatctg aacccgtgta cgtccatgca tagcgatggc acttgctcca
     2581 gctgattgtg ctgctaatgc attttctaca gcaaagacgt gctcttcatc ccaaccaata
     2641 cgcatcttga ttgttactgg gatatttact gctgaagaaa cagcttggac catttcgtat
     2701 actttctcag gatctaaaag ccattttgct cctgcttctg ctttgattac tttatttact
     2761 ggacagccca tattgatatc tattatatcg gcagctgtgt tttcttcgac aaattgagca
     2821 gcttcaacta gactatcttt atttccgcca aatatctgta aacttaatgg atgttctgtt
     2881 tcttcaatgt ggagcatctc taaagttttt ttgtttctga aatgaatacc ttggtcactg
     2941 atcatttcac atacgactaa gcccgcacca aattctttga cagtgactcg aaatgctgaa
     3001 tttgttattc cagccatcgg tgcaacaacg acacgattag ggatttccac attgccaatt
     3061 ttccatgtgt gttccactta aatccctcct aaggcttctt tcttcaatcc atctaattct
     3121 tcttcgctat acttgtattt gttattacag aaagaacaaa ccgcttctgc accgtgatct
     3181 tcgtctatca ttgcttggat ttcttctgca cctaacgcga taattgcttc tgcaaatttt
     3241 tcttttgaac agtcacattt gaattgaaca ggcatttttt ccaaaatgtt caattcttct
     3301 gtaccaagca atcctttcaa tatttcttct ggtgtctgtc cttcatctaa gagggtagag
     3361 attcttggtg tcgtttttaa ttgttcttcg atcttgctga ttgtttcttc atcggcacct
     3421 ggcatgattt ggatcatgaa tcctcccgcc gtcttgatgc tgtcgtcagt attgaccaat
     3481 acactcagtc caacagctga agggatttgt tctgagatag caagatagta agtaaaatct
     3541 tcagcgattt ctccagaaac aatcggcgtt tgcccagaaa aaggttcttt taatcctaag
     3601 tcttttgtga cagtaaacat tccttgtgtt ccaactgctc cccgcacatc gattttacct
     3661 tcactattta gaggaagact gagatgcgga tttttgatgt aacctttcac atctcccttt
     3721 ccatttgcat ctactacaat tcctgttgct ggaccatcgc cttggattcg aacagttagt
     3781 ttgtcttctc ctttgagcgt cgcaccaagt agcagactac cgaccaatgt ccgtcccaaa
     3841 gcagctgagg aggtgtgcca agtatcatga cgtctttgtg cctccgctac ggtatttgtt
     3901 gcttgaacgg cgtatgctcg gacgaatccg tcgtgagcaa gtgccttaac caaataatct
     3961 ttcatttgtt atgtactcct ttttccgttt ttaaactcat agtgaatcat actagcaact
     4021 actgcttttt tcaactttgg aatgcttctt ttaaaaataa ttcagaatca tctagaaaac
     4081 aggacatcac cctatttaca acttaaataa agaaatctcc cgaaaaccgg tttttgttcc
     4141 ggttttcggg agtcatatca gatcaattga cctatatttt tttatttgta ttgatcgtct
     4201 gaatgattat cttctgattg ttgagaatct gaatcatgtt ctgctttatt ttcctcattc
     4261 agttcatgtt ttgcttcttc aaaatcacgt ttttcttccg cttgtttttc agcgtctttt
     4321 tcttccaaag cacgttttgc ttcttcaaaa gttttcgctt ctttttcgct tggataatca
     4381 tttgactcag taccttcagg catcacaccg tgttcaaaca atgacttgat tgctttggca
     4441 tccaatgttt cgaattccaa aagtttttca gcaatcagtt tatgctgtgc acgatgagct
     4501 tcgatgattt ctcgagcttt atcatgagct tccatcaaga tttttcgtac ttcttgatca
     4561 atctcgaaag cgacttgttc cgagtaagct tttgtttgac catagtcgcg gccaacaaac
     4621 acttgatggt ttccttcata ttgaacagga cctaaacgat cactcattcc atattctgtt
     4681 accatgcttc gtgctagagc tgtcgcttgc tcaaagtcat tggaagcacc agttgattgg
     4741 acattgaaga tgatttcttc agctgtacgt ccaccaagta agcctacgat ttgttcaaac
     4801 atatcttctt tcgtcatcaa gaactgatct tcttttggta aagcgatcat atatccgccg
     4861 gcgcgtccgc gagggatgat cgttactttg tggacgaccc gagcgcgact caatactaat
     4921 ccgacaatcg tatgaccagc ttcgtgataa gcaaccattt cgcgttcttt tttgctgatt
     4981 acgcgatctt ttttagctgg acctgcaatc acgcgatctt ccgcttcatc gatatcagaa
     5041 gcatcgattt tctttttatt tcttctagca gctactaacg ctgcttcatt caagacattt
     5101 tctaaatctg ctccggcaaa acctggtgtc tgttgagcca caactttcaa gtcaacgtca
     5161 tctgccatcg gtttattccg tgcatggact cgcaagattg cttcacgacc ttttacatct
     5221 ggacgtccaa ctaaaatctg gcggtcaaaa cggcctggac gtagtaacgc tgggtctagt
     5281 acatcagaac ggttggttgc agcaatgacg attactcctt catttccgtc gaagccatcc
     5341 atttctacaa gcaattggtt caatgtttgt tcgcgttcat catgtccgcc gcccataccg
     5401 gcaccacgtt gacgacctac cgcatcaatt tcatcaatga aaatgatagc tggtgcgttt
     5461 ttcttcgctg tttcaaacaa atcacgaaca cgacttgctc caacaccgac aaacatttct
     5521 acgaaatcag aacccgagat cgagtaaaac ggtactccag cttctccggc aacagctttt
     5581 gctaataagg ttttacctgt tcctggaggt ccttctaaaa gtacacctgc cgggatacgg
     5641 gcacctaatt caacaaatcg gcgaggatct ttcagaaatt caacaacttc aactagttct
     5701 tgtttttctt cttccgcacc cgctacatca gaaaaacgta cgcgattagc ttttttgtct
     5761 gcttctttgg cttttgattt accaaagttc atgacacggc cgccaccgcc accgccgccg
     5821 ccttgttgtc ccatcatcat gtaaaagaaa aagatgatga ttacgattgg caagaagcta
     5881 agcaataggg aaacccatat accgctgctt gattcttctt ttactgttgt agcaactttg
     5941 ttttcttttg ccagttctgt tacttggctc aatgttgtat catttggcaa aatgattgtt
     6001 gtgaaatggg tagtagtcgt atctgttgaa cctaagatag ctaacccacc gctgttagcg
     6061 acggtctgct gttctttgta ttcaccagtg atcttatata caccatttgc aggctgcact
     6121 tcaaattctt tgatcttgcc tgcttgtagt tgttctgtga attttgagta ctcgatatct
     6181 gacgatcgct ggccgttatt accaaaaatg aaataaacga ccattaccat cgctaagatt
     6241 acgaggacat aatacaaggc atttttcatc atgccgttgt tctttttgtt catagttgcc
     6301 ctccctaagc gtcaatttaa tttaacagtt ttttatcaat cctgaccatt ctattgtacc
     6361 ataatttaat tgagatacag cattaatttg attgataaac actaggtttc aatacaccga
     6421 tgtacggaag gttacgatat gcttctgcat aatccaagcc ataaccgacc acaaattcat
     6481 ttggtacgtt gaagccaaca taatctgctt cgatatttac tactcttcct tcaggtttgt
     6541 caagtagtgt aacaattttg actgattttg ctttgcggta tttgaaaaga tccactaaat
     6601 aagcaagtgt tcttccgctg tcaatgatat cttcaacgat caacagatcg cgaccttcta
     6661 cattcgtatc taagtctttg acgattttta cttcccctga cgagactgtt gcattcccgt
     6721 agcttgaaac atccatgaaa tccaattcca aatacgtatc gatagaacga acgatatctg
     6781 ccatgaatgg taccgctcct tttaagacac ctactactag gggattggtg ttttggtaaa
     6841 tttctgttaa ctctttgcct agttctttgc aacgaacttg tatctcttct tgtgagatca
     6901 aaattctctc aatatccttt tccaacatca ggttctcctt ccaattgctt ctttttgata
     6961 tttgtaaaga agtatgtagt gtattttatc agtttcttca cgaatactca aatatgaaaa
     7021 ggcaaaaggt atcaagctat atatatttct tttggcatct gtaatgatcc aagcatgctg
     7081 cctttgtgaa ttaggtactt tctgatcgat aaaatatcta gatacttttt ttgtgagatt
     7141 ctctgttaat ttaatgcggt ctcctgcttt tcttttttcg acatacagtt gcacatcagc
     7201 aggaatccaa atgtcatgag aaaatagaga ccatgaatct gttgctttga tgtcccctgc
     7261 attttcaggt ttgaccagac caatccattc tgtttcattc aaatatattc cttgttctgg
     7321 aatcagcaac aagcgctggt cttctgtctg gctagttgct tgtttttctt ttttagagag
     7381 tacaacaaaa tgatactctc ttttcagtat ccaattattg ccaatactga gttgccattg
     7441 gctttttttc tgttgccact ggtctaaaat cgactccatt tgttgttctt tcaaaataat
     7501 tcctgttttt gagaatgctt tgtcgaaaaa ggagtaaaaa aaatagtatc gttcagcatc
     7561 tgtcatttct tcaatcattt ctgcagaaaa tcgaaattgt tcctcccact gttcgacttc
     7621 cttttcgatc aactgtccca tatatttttg aatgacttgg tctgcccatt ggatctgttg
     7681 cgaaaattgc tggaaatgtc tcaacgcctg tgtattttct tgtttcaatt gaggaactac
     7741 caaatgacga agccgatttc tctggatatc taacaattgg tttgtctgat cctcaaagta
     7801 aacaagctgc gattccgctg cataagtata taggtcttct ttgctaaaac tcagcaacgg
     7861 acgaatcagt ctgcccgtag caaatggttg tacttctttg attccagaaa aagtatttaa
     7921 ctgtccccca cgaacgattt tcattaacac cgtctcgatt tgatcatctc cgtgatgagc
     7981 agtcatcaac gtgtcatatt gtccttcttc catcacgcga gtgaattctt gataacgaaa
     8041 gttacgagct tctgtttcta tggcggattt ggctggatct tcccaaatac ttacatataa
     8101 agggagattc ttctcttcac aatatgagcg aagataggca gcttcttctg ctgattcttc
     8161 tcttaattgg tgattgatgt ggacgatacc taaagaaaaa ccgatttggc gttgcacttg
     8221 taaaagtaaa tggagcaaaa ccatcgaatc aacaccacct gataccgctg ctaaaattct
     8281 cgatccttgt tgccagaatc cttgttcatt cccgtgccga ataaatgact gctgtaatag
     8341 cggtgctttt ttcccgcctt tttcaacgtt catcctttcc acaccctttc ttcctaaaaa
     8401 aaagagagcg ggaaaacgtc taaaacgaca attaacctgc cctctgttga tactatgacc
     8461 caaatagtcg cactatcatt atttgcggct ttttagctgc gacgtccgcc acggccaccg
     8521 cgctttcctt ctgtgtttcg cttcaatgaa gataagcggt catcgctatc tttcaaaaat
     8581 gaactcatca atgaatcgaa gtcttctttt tgagctgaag gttgactgcg agaaaaagat
     8641 tttttctgtg ctggacgatt tcggttgtca cggggatctt tttgttgata ttttttagga
     8701 cggctttctt ctccagattc agcaggttgt tcctgcgctt tccggataga tagtccgatt
     8761 tttccatcat catttactga aataacttta actgttactt catctcctac acttaaaaca
     8821 tcatggatgt cttttacata gccatttgac acttcgctaa tatgaactag acccgttttt
     8881 ccagcaccta gatcaataaa cgcaccaaaa tttgtgattc ctgatacttt tccttgcagt
     8941 tttgctccta cctcgattga cataaaaaaa atgttcctcc taattatttc ccttttttat
     9001 attcctgctt attttgcagt tgtagaacta gttgattgat ctgtttcatt tgtcgagctg
     9061 tctgtatttg attctaatat aggataaact ttttcaccgt cttttgagta aaagaatttg
     9121 cttctggcaa gtttagctac atactcatca tctttcagca atgaaacatc ttggtgcagc
     9181 tgatcaacgt ctgcgttgac ttctttcatt tcagtatttg cttcgactct caattcgttc
     9241 aattgatgca tcctttgcat gtcatggaaa atctgcacac ctattatcgc gaaaatgacc
     9301 aaagcaccaa caaaaattgc agccagtctg cgtcttcgaa aaatcagttg acgttgttgt
     9361 tgctgaaatt cagcatactt tttctttgca tattccgtat ctagcgcagc gattttattg
     9421 ctttttttcg tcacttggat tcgctccaat ctttttgatt gtctttttca ttataccaat
     9481 atcgtgaaag cttgtctaat ctatttctct agtgtttctg tgcgattttc agaaataatt
     9541 tcgtacattt tttgtgcatc ttcttttttg gttgattcat gtaattccgt aattttcact
     9601 tccaacgttt tgttgccaaa ctggactttc aaaatatcgc ctactttgac atcactggaa
     9661 gatttcgcca atttaccgtt gatttgaatt cttcctttat cagctacttc ttttgctact
     9721 gatcgtcttt tgatgattcg ggaaattttt aaaaatttat ctaatcgcat atcttattcc
     9781 tcacttttta atttttttat ttaatcgcag gattttctta ccaaaaggca acattagcca
     9841 ttctcgtact gtaaacagac gaagacgaat cactgcataa atgaacacag aagccccgat
     9901 cccaactcct atcacgctga caaaaaaagc agtggaacga tgagttacag gaccaaatac
     9961 tatattcaat acaccataat acagcagcag tactactgtc atacaaagaa ggctgaacat
    10021 caacttccgt ccaaaatgcc gttctttcca aaaagcattt agctcttttg tttcaattcg
    10081 aacaaaatac caaagcgtca cacctaatcc taaaagggta gacaggcttg cacctgctgt
    10141 tcctaataaa ccggtcagaa aagaagtagt caatcctttt accaatagtc cccatcctgc
    10201 gccttttaaa gaagggcgaa acgagttctt gctttgagca atactttgat aagcttggat
    10261 gactgcagtg aaagcaatgg aaaaaacaaa taatacaagc gctgcatttc ccgcataatc
    10321 tttaaacaac gcataattga tataagggag cagcaaggct aatcccaaag acgcagctaa
    10381 tgctaaagcg gtcgtcaatc taagatagat tttggctgtc tgtaaaaact gacgatagat
    10441 ccggttggtc aaatgacgag tcaacgcagg caggaatgtc gcacttaatg cagtggcaat
    10501 cactaaacct aattgtacta aaggctgacc tcgatcatag accccttttg ctatcttcgc
    10561 accgtattct gacagtccgt aaacttccaa agcatttttt acaaagaaag agtcgatcag
    10621 ctggaaaaag ataagcaatc cactataaat cgaaaccagt ccgccttcta ccagaaaacg
    10681 ccggatcaag ggctttgacg gctgtttgaa caatggaaac cgtcggaagc ttaacgctcc
    10741 tccatgaatc ttttgttcat agtagtgaag gatcccatat gcgcataaac cgccaaaaac
    10801 agctccactc attgctgccg tccctgtttg gtacaccgtc catccaagct ttctaaaagc
    10861 aaacgcacta cagacaatca caaaaacacg aacgaactgc tcaactactt gagaaacagc
    10921 agttggttcc atcaagaatc ttccttggaa attccctcga taaaaagata gaccaggcat
    10981 cagcaaaaag gtaaaggaaa ctacttggat cagcggtttc aattgtatgt ctcccatcat
    11041 ccaagcaatc cagctgctaa atgcaaagac aaacaaccac aaaaagacac ctgtccaaaa
    11101 tactaaggga taaagatttt gcaaagcttg ctttcgctcg aaaggattct ttctttctgc
    11161 aacgtacttt gatatgaact gcggaagacc ggataaagct aaagtcattg ctatcccata
    11221 aattggataa acttgctgat aaacataaaa accttcgtcg ccgactaagt tttggagggg
    11281 aattcggtaa agggcactta atacttttgc tatgaaagaa gcaatcgtca atacaaatgc
    11341 tccttgcatg acgcgccgca tttctttatg atccaaatca ttgctccttc ctacgctgac
    11401 agatattttt gctcacgcaa cgctttgaca aacttttgga tttcctgaag ccatactgct
    11461 tcttccattt ggttggggat cgtcaagcgt atcaccatct gttctttttc aacgcctaga
    11521 ctggctttta gttttgtcgc tgtcagtgct tcgaataact gttccacact atagcgtttt
    11581 gttccaactt tacttagagt aaagactata tgcgcctcct gtttccttat cgtttctagg
    11641 agcgctcgat cgccatccat tttgatctgc ccaattgtca agagatgtgc tacttcttct
    11701 ggatattctc caaaacggtc gagcagatca tcttctagtt catctagcat ttcttgcgaa
    11761 tcaagttcac gaattcgttt atagatctcg attttctgcc gttgatctgc cacgtatgtt
    11821 tcaggtagat acgcatcgac accgaggtcg atctcaacag tggtcttctc cacttgacta
    11881 ttctttcctt gtttacgaga aacagcttcg cttagcattt gagaatacat atcgaaaccg
    11941 actgcatcaa taaatccatg ctgctgagca cctaagagat tacctgcacc gcgaatggaa
    12001 agatcccgca tcgcaatctt gaatccagat cccagttctg taaaatcttt gattgcctga
    12061 agacgttttt cactgacttc gttaaggatc ttctgctgct catacataaa gtaagcatat
    12121 gcgacacggc tgcttcttcc tacccgccct cgcaattggt ataacgtgga taatcccata
    12181 taatcagcgt tctcaacgaa caacgtattt gcgttcggga tatctactcc tgtttcaatg
    12241 atggttgtag tgacaagaac atcatattga ccttcaataa attcaaaaag cgtattttct
    12301 aattgcgcct ctgtcatttg cccatgagca taaccgatcc gtgcttccgg aacgagttct
    12361 tggatttctt ctactttttg ttcgatcgtt tctacccgat tatataaata gaatacttgt
    12421 ccacctcgtc ccatttctcg atggattgct tcgcgaatag ccccaggatt tttttccata
    12481 acatacgttt ggatcggata acgattcgca ggcggtgttt cgattactga aagatcccgc
    12541 acgcctaaca tcgacatatg caaagttctc ggaatcggtg ttgcagtcag agtcaaaaca
    12601 tccacttgtg cacgtaactg tttcaatcgt tccttatgtt ttacaccaaa acgttgttct
    12661 tcgtcaatga tcagtagacc caaatcgcta aattcaatat cttttgacaa aattcggtgg
    12721 gttcctacaa caatatcaac ttgacctgta cgcagttgtt cgatggtttc tttttgttgc
    12781 tttcttgttc tgaaacgact taatagcccg atatttacgg ggaaaccttc aaatctttcc
    12841 agcatcgttt catagtgctg ctgtgccaag atcgttgttg gaactaaaaa ggctacttgt
    12901 ttgctttcct ttatcgcttt aaaggccgct cgaagcgcta cttctgtttt cccataacca
    12961 acatcaccta cgagtagtcg atccattggt ttttcttttt ccatatcccg tttgatctcc
    13021 gctgcacttc tcaactggtc atcagtttca gagtagggga aggcattttc gaattctttt
    13081 tggtaggcgt catcaggtcc aaaagcatat cctttttctg actctcttgc ggcatataat
    13141 ttgattagat cgtcagcgat atcctcgatt tttgaagaga cttttcgctt ggttttcgtc
    13201 cattcacttc cgcctagctt attgatgcga ggcgctttgg cttcagaggc gacatatttt
    13261 tggatcagat tcagttgagt aacaggaata aacagtttgt cgtcgttttg atacaaaata
    13321 gtcatatagt cttggtgaac gccatctact tctagcgttt ccatcccaat gtatttcccg
    13381 ataccatgat tggcatggac aacgtaatct cctgctttta actcattata gcttttcaat
    13441 cgctctgcgt ttgttactgt ttgacgtctc gtttgttttt tcgtcgtttt ttggaaaatt
    13501 tctttttctg tgatagctac tattttttct tgaggaagtt caaaaccagc ctgcaaagct
    13561 ccttcaacta attgtacctg tcctctgatc aatgcatttt tttctgtttc tactactaat
    13621 atgtcttcat ctcgaagcat ttgttctgct ttgcgtattc tgtcctttgt cggaataaag
    13681 atcacaacag tctgtttttg cttgcgccaa cggtccattt ctgttttcag caatggcatt
    13741 tgtccgaaga actgttgcat cgtccgatat tgaaaattat ggattgcttg gaaacgaaga
    13801 tttcccatcc ctttttggaa gagtgagaaa aaggttgtgg tgaacttttc cttctgcacg
    13861 attttttgta tatctgctga aaatgtctgc tcagaaaaca cccgcaattc gctgattttt
    13921 tgagtctgcc attctgccgc ttccctttcg atttcccgat ttgtttccat gattcgctga
    13981 taatcatcaa cgactagtaa actatttgaa gggaaataat ccaagatcgt cacagattct
    14041 tggtaaagaa gatctgagta gaattttgct tcttctgtcg ggacacctgc ttgccagctt
    14101 gaagtcagct gaccgaagta atcttgcaaa aactcgcggt ctgcttcttc tgtggtcgca
    14161 gcaagccgtt tttctagcat tttttgcatt tgctctattc catgttctag atcctctggt
    14221 ccgtagactt gttcactcgt tggggaaacc cagatttctt ccgttttttc gattgagcgt
    14281 tgtgtttctg cttcaaaata ccgcatagaa tctatctcta catcaaatag ttctacacga
    14341 acaggatagg ttgtcgttaa cgggtaaata tcgataatgc ttcctcgaat actgaattct
    14401 cccggttttg cgaccatctc ttctcgtaca tagcccatca aagtcaattg gcgaggaaga
    14461 ttttccacgt ctatctcatc accaatatgc caattcaatt gcgcctgtag ccaagttttc
    14521 ttattcggca gtcgtttgtg caaagatgcg actggcaaca aatagatacc tgcttttttt
    14581 tcttgaagtg cgttaagcgt tgcaactctc tcgcctcgcg cttctggaga agaaaaggcc
    14641 atttcagcag aaagcacttc atccactgga aataaatgga tctgatcttg cggaatcaca
    14701 tgttgcagat cttctgctaa ctgattcgca taatacaaat ttggcatcag aataatcatg
    14761 tttttatttg ttttcttaaa cgctcgagca aatagaagtg ttttcgctga gcccgctaat
    14821 cctgtgatta gttgtctagg cattttttct tctaaattgc tgacccattc ttttacttgc
    14881 ggatcttttc cgactaattg aataatatcc attccttttc ctccttcctc aattgaatcg
    14941 attcatcgca tccacgaacg aatgcccttc tatgagatat tcgactgctt taacagattg
    15001 acacatgctt tcttctatca aaggctgatt ttctttgctg aaaggactaa gcacatgctg
    15061 gactactgtt tttttccctt ctggcctgcc gattcccacc ttgattcgat caaagacatt
    15121 cgtattcaaa tgggaaataa tacttttgat accgttatgc ccgccggcac ttcccttttg
    15181 acggagccgg atttttccca ctgccagatc caaatcatcg tagattacga ctaattcctc
    15241 tggataaatc ccaaaataag tcattagtgg gccgactgca cgaccagatt cattcatgaa
    15301 tgtttgtggt ttgactaaaa ggatcttttc tccattatga aaaaattcgg caacttctgc
    15361 ttcgaacgga ttttttttga aagtagcttg atgctcgcgt gcaattttat ccacgaccat
    15421 aaagccgata ttgtgttttg tatattggta tttggtacct gggtttccta acccgacgat
    15481 cattttcatt tttgttttcc acctaattct aaaaagcagc acaaaaggct ggactgctaa
    15541 ttagcggtcc agtccatcga gcttttttct tttttacact tgtcaatgca tagtataaca
    15601 caaaacaagg cgtttcggct aaaagagaat cgttaataaa tgataaagaa attaaaaatt
    15661 tcttcaaagt ttaatgaaat aattgatata taaaaatagt gaaataacgc acatgtaagc
    15721 ttttacatat aatacaacct tgttatctgt tatattttat agccaaatag cgtgacatgg
    15781 ggcttgagaa atgttagcat aagcatggga aaaaacaaat caatggaagg attgatacta
    15841 aatgactgca gctgcagaaa aaaaagatca tcaaaaagtt attcttgttg gagacggcgc
    15901 cgtaggttct agctatgcct ttgctctagt tactcaaaat atcgctcaag aagtaggtat
    15961 tgtggatatc aatactgcta aaactgaagg agacgcaatt gacttgtctc acgctttggc
    16021 atttacttca cctaaaaaaa tctattctgc tacttacgca gacgcacatg atgctgactt
    16081 agttgttatt acagctggcg caccacaaaa accaggtgaa actcgtttag acttagtaaa
    16141 caaaaaccta aaaatcaacc gcgatgttgt cacacaaatc gttgaatcag gatttaacgg
    16201 tatcttttta gttgccgcta acccagtaga tattttgact tactcaactt ggaaattctc
    16261 aggtttccct aaagaacgcg taatcggttc aggtacctct cttgactcag ctcgtttccg
    16321 tcaagcactt gcggaattag ttgacgttga tgcacgtaac gtccatgctt acatcttagg
    16381 tgaacacgga gattcagaat tcccagtttg gtcacatgca aatgttgccg gcttgcaaat
    16441 ctatgaatgg gtaaaaaaca acccagaaat cgatgaagaa gctatggtta acctattctt
    16501 tggcgtacgt gacgctgctt acacaattat cgagaaaaaa ggcgctactt tctatggtat
    16561 cgcagtagca ttagcacgta tcactcgtgc catcttagat gatgaaaatg ctgttcttcc
    16621 tttatcagta ttcatgaatg gcgaatatgg attgaacgac atctacattg gtgcacctgc
    16681 tgttatcaac cgtcaaggta tccaaaaagt aatcgaaatt cctttaagtg acagcgagca
    16741 agaccgtatg gctgcttctg ctaagcaatt aaaagaaatt ctagatgaag cttttgctaa
    16801 actagacgct gaataatctt tgaacatgac ggaaaacatc tattcggtgt tttccgtttt
    16861 tttattttat cacccttatg gtttctaaat tttttcataa agtagagata accttcgtct
    16921 tttcctctaa attatgctat catgagaccg ttccacccta aacttttact taaggagttg
    16981 tcgatatgac aagatcttcg catcgaaaaa aatcgaaaca tgttgctttg ctttcagttc
    17041 ttggtgttct cttagtgctg atcagctttt atacctatcg cagtacatac tacacaaagc
    17101 attttttgcc gaatacagaa ataaatggaa taaatgtcag caatctaaca gtcgaaaaag
    17161 caaatgaaaa attaaaagaa gcttattctg ataaaaaact ggctattaaa gaagatggaa
    17221 aagtctggca ggaagtacca aaatccgagc tcggctacaa agatgatttc acttcggagc
    17281 tttctccgat cctaaatgaa caaaacggat ggacttgggg aatgacttat gtctcagcgg
    17341 cagaaaaaca agaaatagat cctgtcagtc aaaaccacca aaaactagac actaccgttc
    17401 agacattgac aactaagctg actgatttga acaaagaccg gacacctact actgatgcaa
    17461 cgatcgaaaa agcaggtgac tctttcgtta tcaagcctga agtcaatgga aatacgatcg
    17521 acgtcgatgc tgcggtcaaa caattaaaaa gtgcggtaaa ctctggtaaa gatacaattg
    17581 aattgactga attcaaagaa aaaccaaaag taacatctga agacagctca ctgaaagaac
    17641 aactcgcatc catgaatgct atcgcaaatg taaaagctac ttacagtata aacggtgaga
    17701 ctttccagat cccatcaagt gatattatga gttggctgac ctacaatgat ggaaaagtcg
    17761 atttagatac agaacaagta cgtcaatatg taacagattt aggcacaaag tataacacaa
    17821 gtacgaatga cacaaaattt aaaagtacaa aaagaggaga agttacggtc ccagttggca
    17881 cttacagttg gacgatccaa acagacagtg agacagaagc attgaaaaaa gcgattctgg
    17941 caggccaaga ttttactcgt tcacccattg tgcaaggtgg cacaaccgct gatcatccat
    18001 tgatcgaaga tacgtatatc gaagttgatc tggagaacca gcatatgtgg tattacaaag
    18061 acggaaaagt ggcccttgaa acagatatcg tttccggaaa gccaactaca cctacacctg
    18121 ctggagtctt ctatgtttgg aataaagaag aagatgcaac tttaaaagga acaaatgacg
    18181 atggaacacc ttacgagagt ccggtaaact actggatgcc gattgactgg acaggtgttg
    18241 gtatccacga ttcagactgg caacctgaat acggtggaga cttatggaaa acccgcggtt
    18301 cacacggctg catcaacacc ccaccaagtg taatgaagga attattcggg atggtcgaaa
    18361 aaggaacgcc tgtattggtc ttctaacaaa aataatatat aaaaagaaag cacccgtacg
    18421 attggtacag gtgctttctt tttattatct aacaatgtgc tacttacatt tcagcagcag
    18481 taaagacttc tgaaacatca tcatcgtctt ctagcttatc tactagacgt tccaattgct
    18541 ctttttgttc ctcatttaaa tcaatcgtcg tttgtggaat catcgtcaat tctgcttgcg
    18601 ccaaagtgaa ctctttttcc aactcatctc gtacagcagc aaaatcttct ggtgcagtat
    18661 aaatctcgaa tacttcagga gaagtttgca gatcttctgc ccccgcctct aatacatcct
    18721 caaacatcgt ctcttcatca acagtcaacc catcgcgttc aatagcgata tatcctttgc
    18781 ggtcaaacaa gtaactgact gaacccgttt ctcccagtga tccaccgttt cgagtaaaag
    18841 ctactcggac atttgtcgct gtccgattac ggttatctgt caatgcatgg actaagattc
    18901 ctactccacc cggaccatat ccttcatacg tgatttcatc gtaattcgtt tcatctacgg
    18961 cactcgtagc ctttttaatc gcccgttcca cattgtcgtt aggcatattt gcagcttttg
    19021 ctttgtccac aacaagccgc aaagctggat tcatagatgg atcaggaccg cctgctttag
    19081 ctgccatata aatttcacga gaaagtttct gaaagacttt ccctcgtttt gcatcttggg
    19141 cattttttct tccttggata ttatgccatt tactatgtcc tgacatgatt tttcctccct
    19201 tgttcttttg agaatacact tctattctag tactatttca caaaaaaaca aagccacagc
    19261 caatctataa acgcttcttg aatgccgcaa aaagcacaca taatatcaca gcagtcagag
    19321 caccgatcga atccaacatg acatcttgga acataggtgt tcgtccaccg gtcatcatct
    19381 gatggaattc gtccaaacct gcgtaccctg ttgctgaaag ccaagcaagg atcgctgtca
    19441 gccaccaaat ttttagcttg gggaaaacac ctaaaaacaa gctgcctccc aaaataaaat
    19501 aggtaccgaa atgtgcgccc ttccttaaaa agaactctaa aaatttggcg tagcccagat
    19561 ggttgatact caccatactt ccaccataat taaaacgtat acccgctaat gtgtctttaa
    19621 atggctgatt aggcagccag ctttctaatc gcgaaacttg tgattgctgt ccgtaagttt
    19681 gagaagaact gtaaaataag attataacga ctatcagtgc gattactaaa taaatatttc
    19741 cgtttttcat ttgttttttt gaagaattca taagtcacct ctgtatttta tcttagactt
    19801 tttttgaaga aacaacaatc attttcatag agacttcttc cataaaaaag tgctatactt
    19861 aattttgtat tacaatatga agggagtttt ttcatgagtt attcattaaa ttggaatcta
    19921 gattctattt tttccggagg cagtcattct gatgctttga accaacggat gaagcaattg
    19981 gaagaccaaa tgaacgagta ttatcaccgc gtaacaaaat ggtcacctag ttctgacaat
    20041 gcagagcagt taaacgctat tcttcaattg caagaaacga ttacgaatgg ttttacccaa
    20101 tgcagcagct atattactgc attgctttct gccaatgtca atgattcaga tgcaaaggtc
    20161 ttatcaggca agctttacgc aatgctgcct cgtctgcaat cagccgaaac tgtattgtca
    20221 aagaaatttg cagaaatatc tgacaatgat tggaatcaga tgctttctca atcttcgttt
    20281 gaaacaattg cttttcgttt aaacgagatt cgtcgtgatg gctcacaatt attatcagaa
    20341 gctgaagaaa acattataaa tacgctttct ttagatggtc taaatgcttg gagcagtcat
    20401 tatgatacga ttgtagccag catttcgatt cccttcgaac aagatggaca agtagtcgaa
    20461 ttatctgctg gacaagcctt caataagatg atgggcgatc cagatccaaa agtcagagaa
    20521 acacttttcg cagcatggga agaagcctgg aaagaaaagg cacccctctt cacggatact
    20581 ttgaatcatt tagatggttt tagactttct gactatgaac ttcatggtgt cacagatttt
    20641 ctacaaaaac cattagagta caatcggttg aagaaagaaa cattgtctgt catgtgggat
    20701 acaatccaga aaaacaaaca accccttgtt aattacttga ctagaaaagc taatcttttc
    20761 ggtaaagaaa aaatggaatg gcaagatcaa gatgcaccta ttattttagg cgatttgaaa
    20821 gaaaaaacct ttagttttga cgaagcagca gcatttatta tcgaaaactt taacaaattc
    20881 agtccaaaaa tggctaaatt tgcccaatct gcttttgaaa agagctggat cgaagcagaa
    20941 gatcgtcctg ggaaacgtcc tggtggttat tgtactgagt taccagaaac aaaagaatca
    21001 aggatcttta tgacctacag taattctgtt aatgaggttg cgacacttgc tcatgaacta
    21061 ggacatgctt tccatagcag cacgatgtgg gatttacctt ctttaaatcg cgaatatgcc
    21121 atgaatgtcg cagaaacagc aagtacattc gcagaactga tcgtagccga tgctacatta
    21181 aaagtcgcaa aaacaaaaga agaaaaaatc aatttgctag atacaaaact gcaaaatgct
    21241 ttagctatgt tcatgaatat ccattcccga ttcatttttg aaaatcgatt ctatgaagca
    21301 cggcaagaag gattagtctc agaagataag atcacagaga tgatggttga ggcgcaaaaa
    21361 gaaggctatc aaggagcttt agctacttac catccatatt tctgggctgc aaaattgcat
    21421 ttctttattg atgacgtacc gttttataac ttcccataca catttggcta cctctttagt
    21481 ttgggcatct atgcttacgc caaccaaaag ggagcaaatt ttgaagaaga atatatccat
    21541 ttactacgcg atactgcctc aatgacgacg gaagatcttg cgaagaaaca tttgaatgtc
    21601 gatcttaccc aaccagattt ttggcaagca ggtatcgaca tggtgactga agatatccaa
    21661 acgttcatgg aattgacaga agaatttatc tgatttctat tttatcacaa taaaaaaaga
    21721 gttagtccag aatgggctaa ctctttttga ttaatcattc ttacatgctg acagcaaagt
    21781 caggggcaaa ccattgaact gaaccaactt ttacgctttc gcctggttga ggagcatgga
    21841 tatattgtcc tccgcctaaa gcaatcgcta cgtggtaagt tccgccttgt gacccccaga
    21901 ataacaagtc tccagctttt gcttgagaaa ctgaaatttt tgttccagct gattcttgag
    21961 gaactgtcca accaccgatg tcacgaccag ttacttgcat gtaaacatag cgtgtgaacc
    22021 ctgagcagtc aaagccactt ggatctttac cgccccaaac atatggagta ccaatatatt
    22081 tgtaagcttc tgctacgatt gctgcaccat tcacacttcc agaaggagct ggagcaggtg
    22141 ttacaggttt tggttgttca ggtgttggtg ttggcgttgg agccggagta ctacttcctg
    22201 tgccgtttcc tgtatcaaca ctttgatctg ttgatggtgt tgtaggcgca ggtgttgttg
    22261 attcttctgt tgttgaagat tcaggcactg ttgttgattc ttctgttgct gaagattcag
    22321 gcactgttgt tgattcttct gttgctgaag attcaggcgc tgttgttgat tcttctgttg
    22381 ctgaagattc aggcgctgtt gattcttctg ttgaagattc aggtgttgtt gattcttctg
    22441 ttgctgaaga ttgtgtagct gatgatgatt cttcagtcat tgaagattgt gtagctgatg
    22501 attcttctgt tgctgagctt tgtgcagtag atgaagcttg agtagcttgt gcttcagcct
    22561 ctgcttgttc gcgtgcttct ttttcagctt tttcttgtgc agcttgttga cgagcttgtt
    22621 ctgctagacg ttgttgttca cgaatacgag cttgctctgc ttcagcttct gctttttgac
    22681 ggttcaagtc agctttcttg tcttcagcag ttgcttgttc agcagctaat gaagttttca
    22741 gtacgttcaa atcagcttgt ttagataaaa gatcgccttt ttgagattcc aaagcagctt
    22801 ggttttcagc taattctttt agtttagcat cgttttcagc ttttttgtct tctacagctt
    22861 ttttatcttg tttttgttgt tccatcaagt cgttgtttgc ttttaccatc gttgtcattg
    22921 cttgaacgcg tccaatagca tctgctaatg aatcagcatt caatacagca tcgatgtagt
    22981 ttgagcttgt gttgcttact tgtgcttcgc gtgcttgttt ttggattgta tcttcacgtt
    23041 tttcaatacg ttcttgtaaa tctgcaatgt cttttactaa ttgtgcagat tcttgacgca
    23101 atgtatcttg ttttgctaat aggtcttgtg cttgtgtgtt gatttcagaa acttggcttt
    23161 ctaaggcatc gatttgtgat tgtgcatctg cttgttgatt tttcaagtct gcaatctttt
    23221 gatcttgctg ttgtatctga gaatcaaaat cgtccgccgc ggcagcgatc ggtgatgcta
    23281 cggcagtcaa ggtcattgaa cataccatta ctgctgatat taaactcttt ttcactcttc
    23341 attcctccga ctggcttaat ttaataaata tctaaatata tttaagtctt tcttaacgat
    23401 ataaaaattg taccatagca gtgtgtcaac gatataatag ttatgttaca aaaatgtttc
    23461 aaaacaactt ttaaaaatga caaaactgtt cgtttcagaa aatgatcatg aaaaagccgc
    23521 gttaagtcta gcatttctta agataacaac gattcttttt cgctttcgac ctaaaaataa
    23581 aaaaagaaat tattcatcac tgaataattt cttaaaggga aaaatgaata atacaaatat
    23641 aatcatgttc aacagcagtg taggtcctaa aaaccttgta ataaaatacg tgttatttac
    23701 tactgctaat ttaaaaatca actggaccac catcgtaaac aattcataac ccgtgacaaa
    23761 gatgatcata ctgaaaaatt cagtaaagat gttgacatgg ataacgtctt tcattacata
    23821 catcaaccat acaattaaag ggagagctac tgcatagata ccgataacgc caatatagta
    23881 agcgtcatag atagccccga gaacaatcgt ggtaatcagt aaataacgtt tttcaaacgc
    23941 catactgcaa cataataatg ccaatatcag aaagtgggca tttgacatat aggtgccttt
    24001 cgaccactcc cctagcattc ttgttaaatg accatctatc aacatcaaaa agaacaaaac
    24061 gattggcaga tagtacttca ttgtttcttt cttcaacatg gactaatcct ccgctagccg
    24121 ttggacaatc gtcacaactg acacgtcata catttctgca taaggtttca cataaacttc
    24181 ccgatccagc ccataactat ctggtttcgt tttaataacc gtaccgatcg gcaagttagc
    24241 tggagaattc cctccaagac cggatgtctg gacaacatcc ccttctttga tatccgtatc
    24301 accagttaat tgggtcacca ctaaggcatg gagcttttca tcatagtttt taagcaaacc
    24361 aaacgcttcg ccattagccg aagatacccg tactggaaaa tgattggagc tttcattaga
    24421 ggatgacagt aattcgattt tagacgaagc cgtattgacc tcgatcactc ggccaatcaa
    24481 tcctttttgc gacatgactg ccatatttgc ttcgataccg tctttagaac ccttgtctac
    24541 gatcagcatg tcctgccaac tgtcaggcga acgagtaatg acatttgccg ttactttttc
    24601 gtaactagtc agcgtctgat tcaactcaag ttcttttttc aacgcttcga tttctctctc
    24661 gtaattcttg ttttgctgtg aaacgtcatc atagctatcg attttttctt ttagccgctc
    24721 attttcggca taagttgaaa aaagattatg gacagaatct actccatttc gtacccaccg
    24781 tactggggca gagattgttt tatcaaccat tgcaacactg tcattaacga tggattggaa
    24841 gaaattgggc tttccttcat tcgctcgctg cgcagcggtc acacttagta tcgtcaccac
    24901 gatgataaca ataaccaagg taataataat atttttatta ggattgaact tcttcacaaa
    24961 gacacctcga attaattaga ctcttgtgtt caattttatc actaaatgcc gtgaaacaaa
    25021 aggtaagttg ctcctcttaa gctttttttt agcaaataat agattctgtc atttttagcc
    25081 tgaaagacaa atttttttat ttgtttatgg atcaatcttt gctttgaata actgcaatca
    25141 taccatctga aaaagaaaat tctgcggtat ctgaaagaaa ttcgttactt gcataagatg
    25201 tcggatattc tacttcttta ttttccaata catacttgct gccttttaat gtaagattcg
    25261 agacgggagt caagcagcaa taagctaaat acttcatatc tggtatctgt cttactatat
    25321 gctctccagg caaataataa gacaaataat tttgacaatc tctgataata agctgatggg
    25381 caaagggttt gaagcgaggt tccataccta accagagatt ggctaaaaga tgatccaatc
    25441 ttccgcccgt agctccaatc aaagtgactt ccgcttgcgg gtaacgttca aatgttttta
    25501 agatacctaa ctgtgtatct gtatcgtctt tttctgcagg ggaacgggta tactctttgg
    25561 cttttgcaaa tacttccttc tgctcttcgt tcgacaatga atcaaaatca cccactgcca
    25621 gatctactgg gtagcctgct tgaagcaggt acagcgcacc acggtctatc ccgacatagg
    25681 catcgtattt ggacagcaga gactgcggcc agttttgcgg attacctcca gcagctaata
    25741 aaattttcat ttagtctaat gcctctttta atcgttcgat ttgtccgact ggattttcgg
    25801 ctccatagat atatgatcct gcaacgaaga catccgcccc tgcatcttta cagatttttg
    25861 ctgtttctgg aacgattccg ccatctactt cgattgcata agtccaattg ttctctctac
    25921 gtagatcagc gagttccgta attttttcta ctgtttcttc aataaagctt tgtccgccga
    25981 acccaggatt gacagtcatg actagtactt gatcagccaa aggcaaaaca tgtttgatca
    26041 tggagactgg tgttcctgga ttgataacta ctccagcttt aactcctaag ctttttgtca
    26101 tttgaagtgc ccgatgaata tgaggagttg cttcgacgtg gacagtaatg atatctgctc
    26161 cagcttttgc aaatgctgga atgtagtttt ctggatcaac gatcatcaga tggacgtcta
    26221 acggtaattt agtaacagga cggattgcct gaacaatatt tggccctaat gtgatatttg
    26281 ggacaaatcg gccatccatt acatctacgt ggatgtaatc tgcgcctcct ttttccacta
    26341 actcaatgtc tctttgtaaa ttggcaaaat ctgcactcaa aatggatggt gctatcttca
    26401 ttcttgtttc ctcctatttt cgtttacctt ctttttttgc atacattggt tttctttttt
    26461 cgatttcttg taagaattgc aaataattgt cgtaacgtgt ctgtgcgata ccacctgttt
    26521 ctactctatg ttttacttcg cagccaggtt ctttagcatg catgcactct ctaaatttgc
    26581 aatggacaga agcttctaca aattcaggaa attgtctcgg cagttctcct gcttcaattg
    26641 tcaaaaagtc aatcgagcta aatcctggtg tatctgctac taacccgcca tagataggaa
    26701 tcagttccac atgacgtgtt gtatgccgtc ctcttccaag tgcatcagaa atctctcctg
    26761 ttgctaaatt cagttccggt gatatttgat tcagtagcgt cgattttcct gctccagact
    26821 gacccataaa gaccgatagc cgttctggga agtaacggat cagttctgtc gtatcacccg
    26881 tatgattggg tacaatcacc ggatagccta ttttagtata ggtttgcttg atctcttcga
    26941 ttttttctgg gtcgtctgac aagtcggtct ttgtcaaaaa aataatcggt tcgatcgact
    27001 cgtattccaa ggtaactaga aagcggtcaa gtagattata agaaaatgca ggctctacga
    27061 tacttgtgac aatgattcca agatcaacat ttgtgactgg tgggcgaact aattgatttt
    27121 ttctcggcaa gatttccaga agatagccgt ctgtttgatt ttcactctca aagatcacct
    27181 gatctccgac aagcggcgtg attttccgat tccggaaatt tcctcttcct cttgtttgat
    27241 aggtctctcc gtttgcgtat acatagtaaa aaccgctgat tgcttttctg atttgtcctt
    27301 tgataagtgc cacctccgtt tttgtttatt ttaccatacg aagaggaaag taggtgttat
    27361 tccatgcaaa cttctcaaag tatatggctt gaaaattgat caaaagagat agaaacacaa
    27421 aaaagagaat gcaacaaatc aatgtcgcat tcccttctga tatattttat tcagcactta
    27481 ttttgaactt tctgaggtgc tagctgatga acttgtggag ctggaagatt cttcttttga
    27541 agagttgctt gtgctactgg agctacttga gctgctagaa ctgtctgaag agtctttttc
    27601 agaactagaa gacgctggat ctggtccttt agagtaaatt acgttcacaa ccattccttt
    27661 ggtaattgtc gttcctgccc ctggtactgt acgaatcact ttatctttat ccaccgtgtt
    27721 tgaatattcg gaagtctcat gcccgatata ttctgcaccg acactagcta aataactttg
    27781 tgcttcgctt tttgtatagc cggagatatc attcaattta ggctctgttc cttggcttac
    27841 gacaaaattg atgtaagttt cttctgctac aacttcaccc gaggctggat cctgactgat
    27901 gatcgaacct gatggtacag tgtcgctata gtcataagta gcactaatat tattgatatt
    27961 gaatccttgt gtaacaagcc aattacgaac agtttcgtag ttttctccta catgactact
    28021 caaagtcact gtttctggtc ctttgctgac tgtgaaagta atcgtgtctg ttttaggatc
    28081 gacttctgta tcttctgatg gagattgcga aatgatcatt ccgctttcta cctctgaact
    28141 gaattcctct tctttttgaa tcaagtcagc agaaaaccct aattctttca aacttgcttc
    28201 ggcatcttca taacttttac cactgtaatc atctaatttg atttttttcg tgccgctact
    28261 aatatacaga gtgacttcgc gtttttgctt gactgtcgtt cccgctgccg ggtctgtctt
    28321 cactacatta ccttcttcga ttttgtcatc tgcaatttct tctgtttttg ttgctacttc
    28381 taatttcgct tttgcgagtg tttctctagc agaagcttca gaaagatcag aaacatcagg
    28441 aacaacaact tctcctcgcc cgccagaagc aaagaataca gctgttccga ttcctaaaac
    28501 agcaagaata gctaatagga tcagccacca ttttttctgt cctttctttt taggatcagg
    28561 cagaacttct tcctcctctg gtaaggtttc gttttctggc ttgtcttttg gcagaggcat
    28621 agatttgaat gaatcaggca ttggtgcatc ttccgtaagg ggtgtgataa cttttgtttc
    28681 attatccatc acatgaggct gccatttttc ttcgtttgca cgagctggtg ataatactgt
    28741 agaaagatca tcagacattt cctcggctga cttataacgg tctgcaggtt ctttagccgt
    28801 tgcccgtaaa atcacgtttt ccagtgcttg tggcacattt ggatcaagtg cttttataga
    28861 tggaagatca tcttgaaaat gttttaaagc aattgttaca gcagattcac catcaaacgg
    28921 tacgctaccc gtcaacatct cataaaggat gatccctaaa gcataaatat ctgactgctt
    28981 cgttgccata cttcctctgg cctgctcagg ggacagataa tgaacagatc ctagcatcgt
    29041 attcgtctgc gtgatcgatg tttcagataa agcgatagca atcccgaaat ccgtgatttt
    29101 tacaacacct tcattatcga tcagtacgtt ttggggtttc aaatctcggt ggatgatttg
    29161 atggttatga gctaaagaaa tagcagaaag gatctgctgc ataatattta ctgctgtttc
    29221 ataaggaaca ggataatgtg tttggatata tcgtttcaag tccattcctt tgacgtattc
    29281 catcaccaga tactgcatgt tgtcttcttc accaacatcg taaacactaa caatgtttgg
    29341 atgaacgagt tctgttgctg ctaaagcttc tctctgaaat cgtcgaatcg cagtctggtc
    29401 attttgaaag tcaaatcgta agactttaac tgctacatca cgatccaaga ttaaatcgtg
    29461 cgccaaaaat acatttgcca taccaccgct accgatattt ccagtgattt gataacggcc
    29521 atttaatttt ttgcccaact cgatcataca ctgtcctcct tatattcgat aagaagaacg
    29581 gtgatattat ccgctccgcc tgcttcattg gcacgatcaa tcagctcagt tactttatga
    29641 gacaatgggc cttcttgatt gatgatcgtt cctatttctt cttcagacag catgttcgtc
    29701 aagccatctg aacataacag cagtcgatct tttagttgcc aaagatgagt agaaacatct
    29761 acttcgactg ttccaggcat gccgacagaa cgtgttaaaa tatttttcct tggatggttc
    29821 actgccattt cttcgctgat ttctcctgat ttgactagtt cattgactaa agaatgatcc
    29881 tccgtcaatt gcatgatttt atcttcacga atcaaataag ctctgctatc cccaacattg
    29941 gcaatcgtga accagtcatc tgacagagcg gccgctacga ttgttgttcc cataccgtta
    30001 tattccggct gttcttgtcc acgctgataa atcagcatat tttcttcttg aatcgattga
    30061 atgaaccatt gggcgatttt ttcatcgtca acagcttctt gtttttccca agcttcgcct
    30121 agattcgtta ccgccatctg actggcaatg tctccggcac gatgaccacc catcccgtct
    30181 gctaatacag caagcttgag acctgaacgg ctggtaaata cactggcata gtcttgattt
    30241 gtgttacgtc gtcttcctac atctgattga tattcaatct gcattttttc acctcattac
    30301 tttttgcgca aacaacaaat gaaaaatcca tctgtgtaaa actgatgcgg atacaaagtc
    30361 aacattttct cttcgattga tgattgtagc ataggattgg tcaaaacatc aatcctctca
    30421 aaatcagggt gtctttccaa gaaagcagaa acaacgtctt ggttttcttc ttttaagatc
    30481 gtacaagtgc tataagtcag aataccggaa gactttaaag ttggtgcgca gctttctaaa
    30541 atttccaatt ggatttttgg taaattcgct aattcatccg gctgtttttt ataacgaata
    30601 tctggttttc gccgaagcag cccaagacct gaacaaggcg cgtctactaa aatccgatca
    30661 aactgctctg cttcgaactg tttactgact tctctagcat ccatcttttg agcgtagaca
    30721 gcagaagaga cacctagacg tgctgcatta tcttcaatga gtttgacttt gtgttcgtgt
    30781 acatctaaag cgaccacttc tccaccgcat gacggatcta aaaaagaagc aatatgcgtc
    30841 gtcttacctc cgggtgctgc acaggcatct aagacatgat gttcaggctc gatttgcata
    30901 gacggcgcta caagcatcga actttcatct tggatcgtca tgacgccatc gtggaacaat
    30961 gagctagaag ctaaatgccc ttttttcgct actataccgt atggactgac ttggcttttt
    31021 tcagctgtga tctcttcttc ttgcaaaaca gtgatggcct gatctctgga aagtcggcgt
    31081 gtatctactc gggcactagc atggctaggc tgatatagcg ataaaccgag cttttcagtt
    31141 tcttcgtatc cgatttgatc caccagtcgt ttcgtcatcc atagaggcag gctgattttg
    31201 acagaaagtc tttcgatagg atcagcaatg ccttgcagat ctggtgctcc ttgacgctga
    31261 taattcctca agacaccatt tacaaatttc cctgtcccag gatttccttt tacttttgcg
    31321 atttcgaccg cctcgtttaa aatagcatgt gcagggactt tatctaaaaa ttctaattgg
    31381 tatacagaaa gataaagaag catcttgacc cagtcatcca ctttttttgc tttagcgatc
    31441 aatggtgcaa cgtaaaattc caatagtcgc tgatggctaa tcgtaccata gatcaattct
    31501 gtaaataaac ccacatcttt ttgatttagc tcgctttgtt tgatcatctc attcaacaaa
    31561 agattcgagt aggcgccacc cttgttcact cgctctaatg tcagtaatgc catatatcgt
    31621 actgattttt tcattttttt agggattttt ttcattattt cacctgctga ccaatctgaa
    31681 cttgctgacc gcttccgtta aggaaatcat gtacggcctg ttttccttta ccagctggct
    31741 gtaattcatt gatggctaag acggtctgtt taccgcaagc aatccataga ttttttttgt
    31801 ctttccggat gatcgtacca ggtgctttgt ctgtagtttc tgccaatact tcaaccgata
    31861 ataatttcca gcgtatgccc tcataggtcg tgaatgcaat tggccaagga cgcattccgc
    31921 gtacttggtt gtcaatttct tctgcagttt tatgccaatc gattgcttct tgttcccgtg
    31981 tgatgtttgg cgaaaaagtt gcttctgact cgtcttgagg tactggtttt tgtccatcca
    32041 aaatattggg caatgtttct agcaatagct ttcttcctaa aaggctaagc ttttcaaaca
    32101 tcgtccctac atcatcttgt ttagtgattg gtatgctttc ttgcgcatag attccgcctg
    32161 catccatttt tttgatcatt tccatgatcg ttacaccagt ttctttctcc ccattcatga
    32221 tggcataatg aacaggcgca cctccccgat atttaggaag taaagaagca tggacattga
    32281 ttgcccctaa ttttggtact tgcaataact tttcaggcaa gaattggcca aatgccgcag
    32341 tgacgatcac atcaggcacc aattcaatga tttcttccat ttctggcgaa ccggagattt
    32401 tctctggctg cagcacacgg ataccgtgct tcagagccgc tttttttacc ggtgtcggcg
    32461 taattactcg tttccgccca actggacggt cgggctgtgt taccactgcc tggatctcgt
    32521 aacctgattc tatcagccct tcaagaatcg gcacagaaaa agcaggtgtg cccataaata
    32581 ctagcttagt catcaagatg ttcctccata tattcttcaa gttcttcttc cgggatctgc
    32641 tgtatcattt tctcaatgaa caagataccg tctaagtgat cgatttcatg ctggaaggca
    32701 cgggctaaat agccaaaagc cgtcacttct atctcttctc cgtctcgatc ataataacgc
    32761 acggtcactt catctgctcg cttgaccgtt ccatagacat gcggaatact gagacaacct
    32821 tctacgtcaa ggctttcacc ttttgcttcg atgatttctg ggttaatcag ttcaaatttc
    32881 tcgccttcat ctacttcgat cacagcaatt ctcttgtttt gtcctacttg aggagcagcg
    32941 atccctattc cgtcattcgc aatcattgtc tcatataaat tgtctaataa agcgattgtc
    33001 tcgtccgtga ttacatcgat tggctgagca gttcttttta atttatcatt agggtggatc
    33061 aatataggat agcgcataat ttggcccttt cttaaataaa gtttaatggt tcgttgtcaa
    33121 ttgccacaaa aagaccttgt cgctgttctt tctggcttcc attcaaaatt tcatccaaaa
    33181 catgaggaag attcggttca tgtttatatt tgatgattag ttgataataa tatcggtttt
    33241 tcactctcaa aatcatgctg ggcgttggcc ctaatagcaa gctttgaggg cttaacactt
    33301 cttttagctg attggcaatc tgaaagattt tctttgccgc tacttgttct tcaggatggc
    33361 tggcggttat tttcacagta aagtaataag gaggatagcc tccacgatgc cgtacatgca
    33421 tttcctgctg ataaaactgc tcataatttt gttttttagc caattctatg gcgtaatgtt
    33481 gaggattgaa tgtttggatc acgacttcgc ctgctttttc cgctcgccct gctcgtcctg
    33541 aaacttgggt aagcaattgg aatgtatgct cactagaacg aaaatccggt aaattcaggg
    33601 aggtatcagc attcaacacc ccaactaatg tcacttctgg aaagtccaaa cctttagcaa
    33661 tcatttgtgt ccctaataat atatctgctt cttttgcacc gaatttttgt aaaatctgtt
    33721 cgtgtgcccc ttttcttcga gtggtatcta catccatacg caaaatccta gcttgcggat
    33781 aaagttctcg gagttcctct tctacttttt gagtacctgt tccatagtag cggattttat
    33841 tgccgccaca attaggacag cgattgggaa taggttcttc atgtccgcaa taatggcagc
    33901 gcattgaacg tgtatccata tgcagtgtaa gagagatatc gcaattagga catggaagaa
    33961 caaatccaca gtccctacac atcacaaaag acgaatatcc tcgacgattg agcagtagga
    34021 cagtttgttc ttttttgtct aatcgatttt gtattttttc ctgcaaatta gcagaaaaag
    34081 tagaggtccg atgattctga aactcttcac gcatatctac gatctcaata gctggaagct
    34141 gtgcagctgc tttggctcgg tggtttaact gcaataactg ataaacgcct ttttgagctc
    34201 gtgctcttga ttctaaagag ggcgtcgcgc ttcctagaac tattgggcaa tgatgatatt
    34261 tactgcgcca aattgctaga tctctcgcat gataacgcgg tgtctcatct tgtttgtaac
    34321 ttgattcatg ttcttcatcg ataatgatca gcccgatatt tttcagcggg gcaaaaatag
    34381 cagatcgtgc gcctactact acttgcgctt cttcccgctc aatcttgcgc cattcatcat
    34441 atttttcacc ttgggaaagt ccgctatgta agaccgcaac tgattctccg aagcgtcctt
    34501 tgaatcgctc gaccatttgc ggagtcaatg cgatttcagg cactaacata atagccgttt
    34561 tattttctga caaaacatca gcgattgcct gaagatatac ttctgttttc ccgctgccag
    34621 tgattccctc cagcaaaaag acctgatctt tttgctgctg acctgctgtg atgatttgtt
    34681 cgacagcatt tttttgttct gcattcagtt ccaatgccgt cgtttggtca aatactcggt
    34741 ctttataagg gtcgcgataa cgttctgatt ctataaactc cagccagccc ttttcttttc
    34801 cttgattcaa gacagcagta ctgattcctt tatttttgaa ataagcaatt ggttcttctt
    34861 ggctcagttc agataaacac aaaagaagtt ctttttgttt cttggcattt tgccgtaatt
    34921 ttgcccattc ttcttcgatt tgcttttcag ttaacaaaga acggaccaaa cgaatcgttt
    34981 ttactttatt tcgtgtatgg acttcatatt tgatatctac taattgctct tggcgccagc
    35041 gaatcaattg agaaaggctg ccttcttctt ctgcttcctt ccaggaaatc acttctcgct
    35101 gatcaaacaa tacctgaact tctggtgtgt ctgccaaagg atagatcaat ttatcatatt
    35161 ctgctttcat cacactcgga agcatcgttt gtagacaagt gattttgaat gcgtaagtaa
    35221 tttttttcat ataatcagct aatgaaagta attcttcatt gaccaccgga gcaaggtcta
    35281 gcaaacgaat aactgccttc aaagatggat tagctgattc ttctgatttt tggatagcca
    35341 taacaaatcc ttggacatga cgattgccat taccaaaagg gacttctact cgcatcccga
    35401 cttgcaaagc tgtttccatt tcagagggaa ccaaataagt gaatggctga tcggtctgca
    35461 tagtaggtac gtccacaatg acttcagctg ttaatgtcat ggttcgtttc ctcctttttt
    35521 tgtcttttct tatcaagcga caaaaagttc cttgcctatt ttactagaga tcgatggatt
    35581 tgtcttatct tctgccaaat cctaacaaaa aattaacagc agataagaaa aaaaagaact
    35641 gtgtcaaaaa gttcagacac agccttttct accagacaat aagtggcgaa tgtttgaaaa
    35701 ggaaacagct gggtttgctt ttctttttag atgttcgctc tatttttctt tattacattt
    35761 tttgctcttc acggatacgt gattccaatt cgtgttgttc acgctctttt tgtgcttgac
    35821 gttcctcttc ttccatcttc aaacgttcac gttttaattc aggatgtgga tcattgacta
    35881 catttcctgc atcgatttct tctaaagctt gaccgacgct ttttactgaa tcaaaagaat
    35941 ctagagtagg ctgtgcactt gcatccaatt catgcgcgcg tttacttgct aaaatcacta
    36001 gagaatattt tgaatttaca cgatctaata gtgagtcaat tgaaggtttt aacatcataa
    36061 gactacatct cctttaacat tttaatatat ttaccgatta cgcgatctac tcgaaaatgt
    36121 tcactggcaa taatgttttt gattcgttca actgctagcg gcacttcatc atttacaaca
    36181 gcatagtcgt aaagagccat catttcgatt tcttcttttg caactttcat tcgtttttcg
    36241 attacttcat ctgcatctgt tcctcggcct acgatccgtg attttaattc cgctaaatct
    36301 ggcggagtca aaaagatgaa tacaccatcg ggcacttttt ctttgacttg ttttgctcct
    36361 tggacttcaa tctccaagaa aacatctttt ccttcatcca atgtcttgtt gacatatgac
    36421 aaaggagttc cataataatt cccgacatat tctgcgtatt ccagcatctc tccagcttcg
    36481 atcattgatt caaactcttc tttgcttcgg aagaaataat caacgccttc gacctcccct
    36541 tcacgcattt tacgggtagt cattgagatc gaatactgaa aatcattatc ctcactctca
    36601 aaaattgctt ttcgtactgt gccttttcct acaccggatg gaccagacaa cacgattaat
    36661 aatccacgct ctgacatgac gacgtccttt caactagtct ttttgtactt atcgtttatt
    36721 ttgcactttt tttctgcaac tttcaaggtt atctttaatt atagctagaa attggtaaaa
    36781 aagctaccct gtaccaagag gtcgtaaaaa agctgtcctg catcaagtaa taagaacagc
    36841 caaacataaa cagcttctca tgtttttcgt ttggttgggg ttattatcgc agatgcaagc
    36901 ttttgaacgc cgtgtataag aggtcgtgaa gaagccgatt agtttcgagt atgaagaaaa
    36961 attttgtgaa aatagtttct cacatttttg cataaatttg gcttaatacc gagaaaatgg
    37021 tttttgaaca tcacttattc aaaataaaaa aagattgtga cacgaatttt gtcacaacct
    37081 ttaaatgtat tcctagagca aagaagctaa gcgaagaaat ccaattctgt ttatttattg
    37141 tatttctttg ttcagcatcc ttgctaaaag cccatattgg acaaagtatt cactacaccc
    37201 atgatctcat cttttcgaga acgtgctttt tctgtcggat cttctacctc ttctgtgtca
    37261 attcgaacaa taaatttccg attcatcgtc acgtaagcac cgtcgttgat caaaataaac
    37321 agttcgttct cattatagtc tgcacaggca tctttccata cgtcaaagcc gtttttttca
    37381 gaagggatat cccgtttaac cacagttttt ccacttaatt cgtggaacgt tacgtcataa
    37441 tatttcatta tctctacctc tttcgtcatt caatattttg tacttgttct ctgatttttt
    37501 ctaagatcgt cttagactgg acgacttgat ttttaatttc gattgcattt gatttggaac
    37561 cgatcgtgtt gatttcccga ttcatttctt ggatcaggaa atctaattcc cgacctacag
    37621 gacattgtgc ttcgataagt tcatctagtt tttgtacatg gatcgccaga cgatccagtt
    37681 cctcgtgaat atctccgcgt tccaacaaga tggctagctc cgtcaacaac cgttgctcat
    37741 cgactttcgc tccaagaaat tcctccagct ttttttgata ccttatttga aattcctttt
    37801 catagatttc tacaaaacta tcgagttttt ttagtacttc tttgaattct tcagtattct
    37861 ttttcaacac taaagctaaa gcttgacctt ctttttctcg actcgcctca atagaatcaa
    37921 gtgcgctttt caatgtatct agagctaact gtgccaattc ttccatgctc tcttccggtt
    37981 tttcttctac cgttacgaag ttttcgtcca gcacgaagcg ttccgccatc cgactaattg
    38041 acacttgatt ttgactaccg tatcgttgtt gaattccgtc tgtcaattga gtgataagtg
    38101 aatcaatcaa ttcccagttg atgacgatct gtttttcgtt tttgccaata taagctagat
    38161 tcacaaatac ttcgattcga ccgcggctta actgctgttt aataagctga cgaaaatcgt
    38221 tttcaacaaa gttcaggatt ttaggacttc gtatttgaac atctagaaaa cgctggttga
    38281 cactttttat ttcaatatct aactgatacg cttttgtttc gcggatggct ttgccaaaac
    38341 cagtcatact tttcattcga cagggtcctt cctcattaca tattttctat tgctttttgc
    38401 agttgttcaa actcttcgtt cgtcaatgtc aggcctttcc ccattttttc atggtctggc
    38461 gcccaatctc gaagatcgaa ttttggcggg cgaccattcc agctgactag gttcagttct
    38521 ttacgccacc ccttgttgtt ttctgacaat atagcgattt cttctacgat ttcatatgaa
    38581 aattcttgtg ccatggttgt tcctccttga gataatataa atataggatc agtaatgtgt
    38641 caactggttg cttaagcaat tcatgctgca aacgatcctt gcgttttcct tgtagcagat
    38701 aatcaaaata aacagttttc gtgcgctcat tttgtatttt ttgctggtat tttcgatacc
    38761 ttcgccattc ttcagtactt aattgaccaa tttgtgccaa taaatcatcc ggcatacttt
    38821 ttatatcttg ttggcagatc atttgaatca tcatgtctac ttgatagatt tcattgggca
    38881 gtaaaaaatg tttttttgct aaaagttcta gcatcgccaa tccgcatgtc tctggtacga
    38941 ccctgttctt atataaatta cgcagttttt gccaaaattt tatgcttttg aaaaaagata
    39001 attctaactg aatttctttt gttaagtaag acaaaaatcc tcgccagtat gttcttgcag
    39061 gtttaacaga atgaaatgta taccagttcc catagtaata gcctaatcgt tttttcattt
    39121 ccagatagcc taattgtaaa tttaattggt tcctttggct atcaaaaagc agaaagctgc
    39181 ctagtgtcca caatgtttga catttccaat ggataaaaat gtctggcata cgaatttttt
    39241 tcgctgggcc tggcccttgc acatctacga caaatgcctc tgttgctcct ttgttaatcg
    39301 caatatcaat aggtattttg ttgcgatacc caccgtctgc atatttattt tttccgatct
    39361 ttcgataagc catagcggga taaaatgaag cagaggcgag tatccaatct ggtatttctt
    39421 ctgtttttgt ctgttggata tcagtcacta cttccgctag ttctggcagt ttagtagaca
    39481 ccgtatataa acgtattttg ggattatgtt tgagtaagga caaatccaaa ttgtctttga
    39541 ccatcttttc caatggagca gaagaaaccc cgccttcaat tagtgctgtt ttcgtcattt
    39601 ggcgtctttc tcgatagaag cgttcacgaa ggtcttcaac tgcagccatt tctggtaacg
    39661 caagcacttg tcttgtcgac agctttttcc ataaattcac agcttttttc atatctcctt
    39721 gtaaaatcaa tgcgccgttc aacgcaccta ccgaggtacc tgtgataatc tcaaagttga
    39781 tatcatgttc cttcagcgcc tgccacacac caatctgata agcaccgtgc gctcctcctc
    39841 cacctaaaac aagtgctgta tgatagacca gctttttatt taattgtgtg gttccttgat
    39901 agccgttttt atgaaaaata cgcaaccatt cttctgatag aggagattga aataaaaaac
    39961 aacagttttc tttaataaaa aaacgagcgc aagcttccat ataccgaaaa aattttttcc
    40021 attcaaaagt ttcaccttca atcaacagat tattaaaaat aacatctcct ctacttttag
    40081 caatagtaaa atagacggta tattttttcg atactgcttt aaaagcacat tgcttttttg
    40141 cagaacgcca aaaagcgtct ctactttctt gatgactttg aaaaaatgga aggggttgtt
    40201 ttgcttgctg gataggcgaa tacagcgaca ttttctgtga aaagtaaact ttttttatct
    40261 ccatcgcgct ctcctttttc ttcaagtata ccagtacgtc ataaaaaggt catgagtctc
    40321 gtattcgact ttgtagattc cataagaaaa caattcataa aacctccttt aaataaaaaa
    40381 atacaaaaat cacaaaaatt aattgaaaat gagagtgttt tcaatgaaaa cgtgattttg
    40441 taatggaatt ttaaaataaa agaaacaagc ttttttaatg caaatgttgt aaaataaaag
    40501 agattaagag gaaataagag gaggaacatg atgactgagt cagtttatgt acatattgat
    40561 accacaagta atgctgtttt aacaaaaggg ctgactgcta ctgactttgc aaacagtatc
    40621 gtgcattttc ctcaaaactt gctcttgctt gatccatctg cttctgctgg agaatatgaa
    40681 tcccatacag ggctgaaagt aatccgtggt acagaaaata ttcagcgttt cttttcctct
    40741 tctcgtaaca ggcgtggatt cgatgaattg aagtggatcg actttactga tttaacgatg
    40801 ctgaaagaat tgacaccttt agaaatttca gaattattat attttggtca tatgaaaaca
    40861 catcttcatt cgccgttttt ttataaacta cagaataatt ttgtatactt cgatcttaat
    40921 gatcagctga atcggattta ttatcgctat ttagatgaat tttataggat ttttgctagt
    40981 aaattaagtt cgatcttgtc agataagatc aatgtaaaaa aatctttttt caaaaaagaa
    41041 acacctgttg aaaaaatcag tgtggaatta ttgaaagaaa tgcgtaattt gatgcaggaa
    41101 gggatcattt tttcttttga tcaagttggt ttgatcgatg gtaaatatcg tatcccaatc
    41161 tatgtgattg aagattatat ttggaaatta aaaggcaccc ggtatcgaga agaggaaatc
    41221 atcgctactt taatctactc tgtcaccgat cgacactggc aattggtaga agatgccgat
    41281 ctttcttatc tgccattgaa gtagatctat ttcttatcaa aaaataaaaa ggaaacaaga
    41341 aactaggaca tgattctgtc tcaagtttct tgcttctttt ttatttacag ctcctgtcgt
    41401 ttatctggca caaaaatcga aggagtcgtt tgttggatcc ctaataaaac gatgatcgtt
    41461 acaatagctg tactcaaccc gctggcacca ttcattacga aagaaaagag ccaaggattc
    41521 atcccccata gtgcatacgc tccccagaaa accactcctg caataaaatg ccaaaaatat
    41581 ctggaaagtg cgccaatcaa tgcaccaaac acgatgcttt ttctaatttg tttcgtatta
    41641 tcgtctacat agcctttttg gacatttgaa gccatgagcc ctgctgcgcc tgcaaaagta
    41701 taggcaatcg ggtactcaat caacacttga acgacactta aataataaac ttgtcccaac
    41761 ggaaaatgta ggatgcccca aatgaaacct gccagcatcc ctgcctttgt ccctcttctt
    41821 aacgcaaaaa gagtcaatgg aatctgccct aatgaaatag aaaaactgct gccgatctgg
    41881 atcggaatca acgacaacac catcgctaac gctgcaacaa tcgttccttc tacccaaact
    41941 ctattttttc ccataaaaaa acttcctcct ttgaataaaa aagtcacaaa ggaggaagca
    42001 gctttcgaaa atagtcaaac agctgtttat tcacaattcc tacgctcgca taaccgatac
    42061 aggtacgaag ggtttagaaa tagattcaat ctcagcccaa ttggactccc ctttgtgagt
    42121 ttatttatta tttatttttt gtttcaaaca atggactaac tggtttgttt tcatggatac
    42181 gtttgattgc atctcccatt agtccgccaa cacttacttc atcgattttg tcgattttac
    42241 gatcttctgg aagatagatc gagtctgtaa caactagacg ctcgatagct gaatcttcta
    42301 ttctttgtaa agcagggccg gataatactg gatgtgtaca tgaagcatac acactagttg
    42361 caccagcttc tttcaaagca ttggcagcca atgtgatcgt acctgctgta tcgatcatat
    42421 catcgatcag tacacaagtt ttgcctttga cttgtccaat gatattcatt acttctgcaa
    42481 catttgcttt tggacggcgt ttgtctatga tcgcaatcgg agatttcaaa aattccgcta
    42541 atttacgtgc ccgtgtgaca ccaccatggt ctggtgaaac aacgacaaca tcatcgcctt
    42601 tgattccttt ttctaagaaa taattggcaa taagtggcgc acccatcaaa tgatcgactg
    42661 gaatatcaaa gaaaccttgg atttggactg catgaaggtc caaagtcagc attcttgttg
    42721 caccagcttt ttgaatcatg tttgctacta atttcgctgt gattggttcc cgtgcacgtg
    42781 ctttacggtc ttgacgcgca tagccataat aaggcatgac tacgttgatt gtttttgcac
    42841 ttgctcgttt cagtgcgtca atcatgatca gcaactccat caagttatca ttgactgggc
    42901 tgctcgttga ttgaataaca tagacatgcg atccacgaat actttcttca atgtttactt
    42961 gaatttctcc atcactaaat tgagtaacag atgattttcc taactcgacg ccgactgctg
    43021 ctgcaatttt ctctgctaat gggcgattgg aatttaacgc aaaaattttt aatcttgggt
    43081 caaagtaatg ttttgacatg gggacctcca ctttcttttt cacaactcta gaattctacc
    43141 taataaatag tagtcatatt ttttaaataa atcaagtgat tttgcaaaag tcttagttta
    43201 gataagggag tttttttgca tatccttctt tattgacttg tcttgctctc gcaattgcca
    43261 gcgcatattc tggaatattg tctgtaattg ttgacccggc agcaatcgaa ctgtttttag
    43321 ctacctcgac aggtccgatg atattcgtgc tagaaccaat aaagctgtgg tcgccgacag
    43381 tcgtatgatg tttgttcttt ccatcatagt tgacgaagac aacaccacat ccgacattga
    43441 tttcttctcc cagcgtagca tcaccaacat aagtcaagtg accgacttta gttcctttgc
    43501 cgatttgagc atttttcact tccacaaagt ttccgatatg gacgttttcg ccaatttcag
    43561 cttttggtcg taaatgtgca taaggtccca catctgcatg tttcttgaca tggctgcttt
    43621 caatgactga gttttcaatg acgacgtgat cctcaatcct actgtctacg atttttgaat
    43681 gtgacccgat gacacaatca gaaccaatga ctgtatttcc ttggatttgt acacctgctt
    43741 cgatcaatgt gtctggaccg atttctacgc ctgcatcgat gtatgtcgtt gctgaatcga
    43801 caaagcttac gccattgacc atatgcatct ggttaattcg ctttctcatg atctcatttg
    43861 ctttagctaa cgcgatccga tcattgactc ccattgattc ttcaaaatca tccgtttgat
    43921 aagcagcaac tgtatggcct tcttctttta agatttcgat gatatctgtt agatagtatt
    43981 caccttgagc attgtttgtt ccaactttgc ttaacgcatc gaacaaagct tcgttgtcaa
    44041 aacagtaagt tcctgtattg atttcttgta caagagcttc ttctggtgtt gcatcttttt
    44101 gttccacgat tttttctacg atcccaatat ggtcacggat gattcgtcca tatcctgttg
    44161 ggttttctgc ttgtgccgtc aagatcgttg cacttgcatt ttttccttgg tgatattcaa
    44221 aaagattgtt cagcgtttca gtagtcaata atggtgtatc gccactgata actaacgttg
    44281 ttcctttttt tccttccaag aaagaagcag cttgcaaaac agcatgtcct gttcccaatt
    44341 gttctgcttg taacgcatat ttactgcgtt ctcctagttg tgctttaact tgttctgctc
    44401 cgtgtccaac gatcgtaatc acttcatctg gtttcgtttc actgacccga ttaatgatat
    44461 gttctaccat aggtttacca gaaacgggat gtaaaacttt atataatttt gacttcatgc
    44521 gggtaccttt ccctgccgcc aaaataattg cataacgtgc gtccaactgc gtcactccta
    44581 aatatagttt gctgatttca gtttatccca gtatacccat tttttcaaca aaacaagtga
    44641 ttttctttta tcccagcgtt ttctggataa aaaaatagat agaccataac gggcctatct
    44701 atttggtaac cggtgctctc ctgccaactc ctcggtcaca agtcacacta ctcataaaac
    44761 atgaaaagct gttttttgaa atcgtttctt gtgacttaga gttaaacggt aggcttacaa
    44821 cctcttcatt aaacgttttt caatcagctg accttcggta ttagctcaat aaacggcaaa
    44881 atatgaggag caatttttcc gtttattgag ctaatactca ggacaggacg ctgatttcac
    44941 aacctctaga taaacggtgt tcaaaagcca gtttctcggt attaagccaa atttatgaaa
    45001 aaatgtggaa agccattttc acaaaatttt tcttactact cgaaactaag cggctttttc
    45061 acaacctctt attctgaaaa ataatttcct ggcacaaccg taatattttt cgtttgagta
    45121 tctacatctt tgacataaag cagtgacgta taatcatcga tggcgcgatg accgttgaat
    45181 tttgattcgg caaatacagt gatgccaaca agttctgatt cgaattcttc aatcaagctc
    45241 ttcattccgt tgactgttcc gccgcctttc atgaaatcat ccactacaag gacacgtgaa
    45301 ccacgtttca aacttctctt agacagttcc atcttttcaa ttctttcaga agatccagac
    45361 acatagttga cacttactgt tgatccttct gttatttttg agtcccggcg tacaataacg
    45421 aatggcgcat tcagataata ggacacagct tgggcaatag gtacgccttt tgtggctaca
    45481 gtcattacag catcgatttt ttcaccaagg tatttagaag caatgattct tccaacttga
    45541 cgcagcagtt caggttctcc taacaaatca gagagataaa catatcctcc tggaagcaga
    45601 cggtcttgtt ctgatagacg ttctgctaga gattcaatat attttttcgc ctcttcatat
    45661 gaaatttcag ggatgaacaa tacaccacct gcagcacccg ggattgtttc caaggttcca
    45721 taccctcgtt ctttaaatgt tttcttgatg attcccaaat cttcactgat agaagattta
    45781 gcagattcat aacgttcggc aaagcttgtt aaggaaatca attcatgcgg gtgattcaat
    45841 aaatactgtg tcatgtcaac tagacgttca ctgcgacgta ctttcaccta ttccaactcc
    45901 ttttaagaaa ttttatcgtt ttacattata taagtttttc ttcaaaaatt cgagcatttt
    45961 atgaaaaaat aagaaaatag ttcggtattt attaaaataa aaagaagcct ataaaaaatt
    46021 tttcgttttt ataaggcttc ttttctttat aatttagtta ttttttcttc tgaaggcaac
    46081 caatattcgt ttgatgatat ttacaatcag gaacaaagca ataaagacta atgtgattgt
    46141 tgctcctgga ggtgtatcta gataaaacga gctagttagt cctgacagca tccctagaaa
    46201 tcctacacaa acactgatag caatcacgac attgaagctt ttgcctaatc gcataccgat
    46261 tgctgcggga agaaccatga ttgcggatat caaaagtgca ccggcaatcg ggatcatcac
    46321 agcaatagcc acaccagtaa tcacattgaa catcatcgac atcaaatgaa cgggtagccc
    46381 atccacgtgg gcggtatctt catcaaaagt cagaacatac atcggccgtt tgaataaaaa
    46441 gaacaatata ccgatggcaa cgaataagat tcctaaaaag atgacttgct cccatgtaat
    46501 ggtcacgatc gaaccaaaca gataggattg gatacttgtt gctgaattcc ctccgctcaa
    46561 attcatcaat actaacgcta gcgccaaacc accagccatt aaaatggcaa tggagatttc
    46621 tgaataggtt cggtagatcg ttcgcagata ctccaatatc acagctgcta atacaacgac
    46681 tagcatggtc gtaagtgtag gattaaggtt caaaaagaat cctaacgcta cccctgctaa
    46741 agagacatga gaaagcgtat cagccatcag cgattgtctt ctgatcacta aaaacacacc
    46801 tagcatcggg gcgattccgg caatgaagat agcggcaaga aacgctcttc tcatgaattc
    46861 atatgaaagc aacgccattg agaatcctcc tttctcacca gtcggatctg tctgtccgca
    46921 tactgtttga tatcttcatg atcatgggtg atcattagaa ctgatttccc atggacatgc
    46981 gcactatgtc ggagaagacg ataaaattca tttctggatt cttcatccat acctgttgtt
    47041 ggttcatcaa gaacaaataa gtcagggtca gtagcaaaaa tacgcgctaa actgattcgc
    47101 tgcttttgtc cgccagacaa ttcacctatt cgccgatttc gcatatccca catccctaca
    47161 gcttctaaag cacgctgtac atgttgatga tctttttcag agagacgctt gaaccagcgg
    47221 cctcttggat atcttcctga acggactaat tcgatcaccg tactaggaaa acctgcattg
    47281 aaagatgcaa cttgttgagg aatataaccg atacttaatt tttttccttc ttgatttttc
    47341 tcagcaatct ttatcattcc ttttgaaggt ttcagtaatc ctaacgatgc tttcaccaag
    47401 gttgacttgg ctgctccatt ttctccagtt aaaatgacaa attcacccgc atctacatga
    47461 taagagacat cttctagtac aggttcatca tcatagtaaa aggtcaaatc agatatttcg
    47521 atataacgca ccttacaacc tccattctaa aacttaattg atactttctt ttaaagcttt
    47581 cagatttttt tccatgacag aaatataatt ttcgcctgct ttgatttgtt cattagtcaa
    47641 gctttctaaa ggattcaaca cttctagctt cactcctgtt tcattcgaca atgtctcagc
    47701 taccttcgaa gaggcatttt cttcaaaata aatcactttg atgttgtttt tcttcacaaa
    47761 ttcttttagc tcagctaagc gacttggtgt gggttcctga tctggtgaaa cgcccgaaat
    47821 cgctacttgt tttaagtcgt attgattcgc taaataagca aaagcagcat gctgagtgac
    47881 aaatgtgcgg tttgttgcat cttttagctc atcggagtat ttttgatcca gtgcttcaag
    47941 ctttttgata taagcatcgg cattcttcgt aaaagtttcc tttttatctg gatatttttc
    48001 gcctaattct tcagcaatcg ttctgacttc ttttatagct aataccggat cgagccaaac
    48061 atgtggatcg tattcatgtg aatgaccatg cccttcttct gattcttcat gttcgtctgc
    48121 ttcttgcgat tctaaacggt cgattccttt agctgcttcg atcatcaagg tctgtttgct
    48181 atccactgaa tcctttaacg aatccacaaa aaattccatg tctgaactat tatacacgaa
    48241 aacatctgca tcggaaattt ctgctctttc ttttgcactt ggttcgaaat catgcggctc
    48301 cgttccagca gggatcaaaa gtttcacgtt tccttcatcc cctacgatct cttttgtaaa
    48361 atcatacatc ggataaaaag tcgtaacgat cgtcaaatcc tcttttttgt ctgcttcctt
    48421 gttcgtattt ccacatgctg caaacagtaa agcacctatc attaccgtag ctgtcaaaag
    48481 atattttttc atttatatgc tcctttcaat gaacaaatcg gaattttacg atttattaac
    48541 gtgaactaat gtatcaaaat aaaaaaacac agtcaataga aatccatcaa tttctgattt
    48601 aagcatgtat attcttgatt aaatcgtaaa atggatgagt tgctgctcat atctagccat
    48661 ttcactacaa taaaaaactg aagaatacca ttttaggatt cctcagtttt tcatcaccta
    48721 ttttacttct tatattttat tgcagggttc gtactaaata aacttcctca caaaaacctt
    48781 ttaacccatt atatactctc tgcgctcttg aataatgttg acacaaggca aaaacggttg
    48841 gtccgcttcc actcatcaat gcagcatctg ctccgtactt gatcatacgc tctttgattt
    48901 gatggatgac tggatgccgc tttcccgtta tatcttctaa actgtttccc atttttttga
    48961 tcatctgctg ataatcttgc tctcggatgg cttcagcaag tccgtggatg tcttgatgtt
    49021 ggatggcttg cgtatctact tctctaaaca ctgtacgtgt agagacactc attcttggtt
    49081 tgaccaacac aacccagcac tgtggcatag aaggtaatac ttggatttct tcccctttgc
    49141 caccgacaaa tgccgtactt ccgtagacac agtaaggaac atctgtaccg acttccaaac
    49201 cgatttctgc cagttcttct aacgaacagc ccagattcca taattggttg atccctctta
    49261 gagcagctgc acagtctgta cttcctccgc ctaatccagc tgctactgga atattcttct
    49321 taacaaagat cttgacaccg gttttgatat tgtatttatt ttttagcaat aaagcagctt
    49381 gataaacatt gttccgttca tctaccggta aaaatgcttt atttgtttct acaatgattt
    49441 tgtcttctgt tatttcttca aaaaatagat gatctgccaa gtctacgctc gacatcacca
    49501 tttccaactc atgataccca tcttgccgtc tatataatac atccagtcct aaatttatct
    49561 tggctggcgc tttttcaatc aattccatcc tctcacccat tcgaaaagtc taagtcgcaa
    49621 gtattctatc atagggaaaa ataaaagtat agcttatgtc tgcctagtgg ttgattttgt
    49681 catcgtttca acagctttca cagaattttc tcttcataat ccaaacaagt tctagtgatt
    49741 cttataattc tgtgagcact tcttctgcca aactcggaac atttcctttt tcttttccta
    49801 tcagactgag tagctgcatg gtagcaaatc cgaaattact tcctttccta taagcaaagt
    49861 aacgtccttc ccaatgatcg acatatttta atttcttttc ataagcagac tggaaggaat
    49921 agaaaaaatt accataatta tatacgatat gcatgacttt ttcttgaaag aaagaaaaat
    49981 ctgtttctcc aacattagct aatggagcta agcctagatt ggcttccgag tagcccattt
    50041 tctcgtatac aataaacaga ttggctaaca gatagtcagc taattcctca gattctttag
    50101 gtaagacccg caacaaatca tatcccgcct gcttcttcgt catcggctga gcggtgatga
    50161 agccaacgac tttttgatct ttacggacaa taccgacacc gctagataat acatatgatt
    50221 tatcaaatcg tcccacagag aagtattttt ctcgtgcacc ttgaagccat ttttgtgaaa
    50281 cttcatttac agcttgatgt aattcttctg gcagttgatc gtaccaagta aaatggtatc
    50341 cttctttcat caaacgttga tattcaagtt gctgactcag ccgagacaag tcttctgttg
    50401 ctagatcaac aatccctgct tcacctactt tcgtgaagtg aaaacccaat tcatgaagca
    50461 tcactacgta gctttctgat atcttataaa acgcaagctg atagcctaaa caatctgctt
    50521 gtttcataaa ctgattcgtt gctgcccgca tcattttagg atttccaact ggatctccta
    50581 aaacaaagca tttgtttcct ttgatctgat aaccaaaaac gacttgatct tggtcatctt
    50641 cttggtaata aaaataactg taacctgaca agcgaagctg atggcttgta gctgtgcctc
    50701 cgtatgtttc caataaacgg tcaaaacggt ctttttcgta ctcactgcca agcttcgtag
    50761 tatcttcagc taaatattga taaagcgcca ctaaagctag caatgagatg cccaaaccaa
    50821 taagccctga gaaccacaca tcatctgaag gaaacaaaat aaaatggttt cctgttattc
    50881 gaccgactaa aaagcgtccg ctgtgatagc ctgcaattgc gtaaacgata aacaaaaagc
    50941 cgaacaagct agcatcaaag attatagctc cccaagaata aacgaatttt gttcgataaa
    51001 attcttttct ggataaccac acagctaaca gaatcaagac atataccaat atcaactgcc
    51061 aagataacgt acgtgtgatt gtatttaaaa taccaaaaga tagtaaagca atcgtaggca
    51121 gaaatgcctt tttgactttt actgaaagtg ctctagcaag gccgagtaat aaaaagccaa
    51181 ccaatagatt cactgtctga tctaaaaaat tgaatgagaa cggcaataat acttgaaata
    51241 gccgactgat tgcagacaga ttagtgattg ttgatagaag taccatcatg attcccgcaa
    51301 aatagacagc acttacgagc acgatatgcg caaccttttg gaaaaacagt cgcggaatgt
    51361 tatctaaaaa tcgattgatt ttgactcctg tatgtgtgat gaacaataga agtcccgtca
    51421 taaaaggtag aacataataa aacaaccgat aatataatag ccaaactact gctacatctt
    51481 gccgaacaga caattgactc attcctaaga tcatcaaaac gtcaaaagtc cccattcccc
    51541 ctgggaccat cgtcagcatt cctatcaatg tagcaatcat gaacatagga tagatcgaaa
    51601 gcatcgaaat atctattctc atcaacttgc cgatgatcaa aaataccgca agggctcccg
    51661 tccattgtcc aaaggatgcc agtagcagac caagcaagcc ttttggataa aactcagaga
    51721 acaaggtctt tctctttaga taagcaaaaa agaaaatgac tggtgctaaa aaactaccgc
    51781 cgaaaagcca gatccaatag cttcgaaaaa tactttctga ctgaataaaa aagacatcaa
    51841 taaatgtaag aaacgaccat acagacaaac cagtcagcat aaatagtgcg acttttgata
    51901 cagtggctaa aaccattttt ctatttgtct gctttccata aaaactagct cgcaggcttg
    51961 ctcctaccac accaccaaaa ccggcgagat tgttgatcgt gtttgttacc cacgcagcaa
    52021 gaagaaactc ttttctttcc atttttggtt ttccttgttt ttctaagact ctgatcgtca
    52081 cccaatcata caacaacatc ggagtgacac ccagcagtcc agccagaatc atgagcagga
    52141 tcgtcatgcg gctttgttgt cccatccttt gccaaatatc ttgccaactc atgccattag
    52201 caatatttgc gacttgattt gccacaaaga ctaacacgga gccgaaaaaa atcagtttta
    52261 aaatcagact atgttccttt atccattgca gcatcaagta tcgtttattt ttcacatttt
    52321 cccattccta acttgtatac ttttgtgtca taccccaatg ttatcttatt tattttaatt
    52381 tttccacttt agacctgttc tttgcttgcg atgatagaaa aagaaagata tcctaatgct
    52441 aaaggagagg ataacatgaa agtaggattt atcggcacag ggaatatggc acaagctatt
    52501 attgatggtt tattaaaaaa aggaacagtc tcgaaagaag aggtgttcgt ttccagtgga
    52561 cattttgaaa atgcacaaaa atttgctgct gaaactggcg tccatgcatg caaaagtaat
    52621 caggaagttg catcacaatc agatatcgtt cttttagccg tgaaaccaaa aatcattgaa
    52681 aaagtattgg aagaactaag agaatatagc cagaaagtct tattcatttc tattgcttca
    52741 ggaaaatcat taatagattt agaaacagcg cttgaagatc ctcaggcctc catcgtacgt
    52801 gtgatgccga atgtcaatgt cagcgtagga gcaggcgttt ctgcgatttg caaaaatgaa
    52861 gctgccacgg aggaacagct tcagcaagct acgatgattt ttgaagcaat cggcagcgtc
    52921 tatcctttag cagaatcaga tttcagtaca ttcattggcc ttgctggcag ctcacccgca
    52981 ttcgtttaca tgctgatcga tgcgatggga cggactggtg tactgaatgg tttgtccaaa
    53041 cagacagcca ctgagattgc tgcaaaagca attatgggtt cttgtcaaaa attcctttca
    53101 agtgataaaa atccatggga acttgtagac caagtttctt ctcctggcgg tacaactgtt
    53161 gcaggtgtag ttgccttaga agaagcagga ttcatcccag caatcatcaa aggaatcaat
    53221 acgacgatcg agaaagatct tgagatgttg aataaaaaat aatgatagca atgttttttc
    53281 gtgccttaca aaaaaagaag agctgtggct tttgccgcgg ctcttctttt gtatttttta
    53341 ttatttagca taatcagttg cacgagtttc ccgaataacg attactttga tgtgtccagg
    53401 ataatccagt tcttcttcga ttcgtttacg aatatcacgt actaaacgaa cagcgtctaa
    53461 atccgagatt tcttctggct tgaccattac ccgaacttcg cgtccagctt gaactgcgta
    53521 acttgattct acaccggcga agctgttcga aatattttcc agacttctta aacgacggat
    53581 gtagttttct aatgattcac ttcgcgcacc aggtcttgct gctgagagcg catctgctgc
    53641 agctacaagg acagagataa cagaagtagc ttccacatct ccatgatgag aagcgatcgc
    53701 gttgattact actgggtttt ctttgtactt ggcagctaat tccgcaccga tctcaacgtg
    53761 agatccttca atctcatggt caagtgcttt cccaatatca tggagcaacc cggcacgttt
    53821 tgctaattgg atatcttcgc caagctctgc tgctaagata ccagctaatt ttgcaacctc
    53881 gaccgaatgc ttcaagacgt tttgtccata actagttctg aatcgcagac gtccgatgat
    53941 cttgattaga tctggatgaa gtgtatgagc accgacttca aacgctgcct cttccccgta
    54001 ttcgcgaata cgttcatcca tttctttacg agatttctcg accatttctt cgatacgcgc
    54061 tggatggatt cgtccatctt gtatcagttt ttccaaggtc atccgtgcga tttctcttcg
    54121 gattggatcg aatccggaaa gaacaactgc ttccggtgta tcatcgatga ttaaatcgat
    54181 accagtcagc gtctcaagcg ttcgaatatt acgaccttct cgtccaatga tacgaccttt
    54241 catttcatca ttcggaaggg taacgactga aacagtcgtt tctgaaactt gatctgctgc
    54301 gcagcgttga atcgctaatg ataataagtt tttcgctttg cgatctgctt cttctttggc
    54361 acgctgttca gattctttta ccattagagt taactcatga ttcagctctt cttcagtcga
    54421 tttcatgatg acatctcgtg cgtcctcttt tgataaacca gcaatttttt ctagttcttt
    54481 ttgttgatct tcaatcattt tttcaacgtc tttttctcgc tcttcaatta attgctgttt
    54541 tgaactaagt gcttcttctt tactttcaag tgagttctcg cgtttttcta acgagtcatc
    54601 tttacgattc agcgtttgtt cgcgttgaat caaacgattc tcttgagatt ttaattctaa
    54661 cttactttct ctcagctcac tttcaacttc agaacggtat ttctgatttt cttccttagc
    54721 ttctaacaat gcttcttttt ttagagtttc tgcttctttt tttgcactat cgatgattcc
    54781 agcagctgat gattgtgcac cagctatttc tttctcgtga cgtgactttg cgaccataaa
    54841 ccctaaacca agaccgacaa ttaaaccgat gatagcgagg agaatgttga ataccataaa
    54901 atccacctcc atactatctt tttcattttt atcatctata cagcttctat gataaattat
    54961 tctaaactcg tcaatatgca tcttcgcata tatgtgtaca aaaaacatgc acaactttat
    55021 tctaatgttt gtaccccgta gtgtcaactt taaataaaca aagaaacggc tttctactta
    55081 ttcattaaac gatggttttt aaaataaatg acactagttt catataggta aacctttaaa
    55141 ttgagaaact tttctattaa attattcttt gtagatgaac agatattttt attttatgta
    55201 cccactcgta taattaaata actcacgatt tctttattca ataaaaaaac ggcaggtcaa
    55261 ggagagtacc tactcttcag accagccgtt tttgtttatc ataattttta ttcttctact
    55321 aaaggcaatt cttcttgtcc tttttcatct tctgggacag cgacttcttc accaatacca
    55381 taagctgctc taactagagc agaaacttct gccatcattt caggatgatt agccatatag
    55441 attttagcgt tttcccgtcc ttgaccaatc cgatcttctt tataagaata ccaagcaccg
    55501 cttttatcaa caatgtcttt ttctactgcc atgtctagaa gttctccttc ttgtgagatc
    55561 cctaaaccat acatgacatc tacttcagcg attttgaaag gaggtgctac tttgtttttt
    55621 acgactttga tctttgtacg gttaccaaca atatctgtac cttgtttcaa ttgttctgca
    55681 cgacgtactt ccaaacggat cgttgcgtag aatttcaatg cgcgtcctcc aggagtgatt
    55741 tctggattcc caaacatcac gcctactttt tcacggattt ggttgatgaa aatagcgatt
    55801 gtttttgttt tgttgatcga accagagagt ttacgcaatg cttgagacat caaacgtgct
    55861 tgtaacccga catgtgagtc acccatttcg ccgtcgattt ctgctcgtgg aactaaagca
    55921 gcaactgaat cgactactac gatatctaca gccccacttg atactaaagc atcagcgatc
    55981 tctagacctt gttctcctgt gtcaggctgt gaaagaagta gttcatcgat attcacacct
    56041 aatttttgtg catattgcgg atctaacgca tgctcagcat caatgaaagc ggccgttccg
    56101 ccattttttt gtacttctgc aatagcgtgt agtgcaactg ttgttttacc tgaactttca
    56161 ggtccatata cttcgatgat acgtccacgg gggtaaccgc cgacacctaa agcgacatct
    56221 aacgcaagag agccacttgg aattgtagag atttgttggt cgattttttc gcccaatttc
    56281 ataatagagc ctttaccata gctcttttca atttttttca gtgcagcatc taaggctgct
    56341 ttacgatcat ctgccaatac gataatcctc cttatattta caaatcagag caacatttca
    56401 ttatccttat catatctttt ttagtgaaaa aaagcaagaa aaaaccgaac aaatattcgc
    56461 atttatcatt ttcttaaaag ctgttttctc aaaagatcaa atccttgcat aaccgcatta
    56521 tatctgatag cagcacgatc tctggcaaag tgatattttt ccgaaaccac gccgtcttta
    56581 gatgaaatag cgatccatac tgttcctgca gattgacctt ctaacgtgtc cggtccagcc
    56641 actccggtga aagctacact gtaatctgtt cttgctatct cacgtgcttg aatggccatc
    56701 tgctccacac attctttgct gactgttcca tattctgcta atagctccgg atcaatctcc
    56761 agaaaaccag cttttgtttg gagcgagtag gtaacgaatc cgcctggaaa tacttcagat
    56821 acaccagcaa tgtcgcctaa tgcggcttgg aaggcgccgg ctgtcaaact ttccgctgct
    56881 gttacagtct gcttgttttc tttcagtagt tccactacga cttttgctag cgaattatca
    56941 tcgccgtatc cataaaaata ttcccctact cgttcttgga ttttttcttc taatgctaaa
    57001 agagcttgat tccctgcctg aacatcattt gttttcactg tcagtcgtaa tgtcacttca
    57061 tttggtttgg catatggtgc gatcgttgga ttgatctgtg tctcaatcag atcttttagc
    57121 tcagtgacca gtcgcgattc accaatccca taaaagcgca aaactttaga aattagtttt
    57181 tcttcagaag gaaaacgttc ctctagtaaa ggacgtactt gttccacaaa cattggtttc
    57241 aactcattag gcggaccggg aagaaggata tacgcatgtg tatctgtttg ataaaaagtc
    57301 cctaaagcaa gccctgtacg atttggtaga ggaaccccgc cttcgataat ctgggactgt
    57361 tgcagattgt ttttggtcat ttttcgatgg gttgtttcaa aatatgccaa taattttttg
    57421 tatccttccg tattttgtat gagagactta ccgaggtgag ccgcagttgc ttcttttgtc
    57481 aggtcatctt ctgtcggtcc taatccgcca cataagagta tgagttcact tcttgtttca
    57541 gctagagcaa tcaactcttc taaacgctgc tgattatctc ctacaactgt ttgataataa
    57601 acttcgatac ctagatcagc tagctgttct gacaagaaag tggcattcgt attcacgact
    57661 tgtcctagta aaagttctgt tccgacagct attatttctg ctttcattac ttcccgctcc
    57721 cttatatagt atacgctgta tttttatatt tttttattta aaaagagggc aaggagctgt
    57781 gacaaaaatc ttgtcacagc tccttgttcc aaataaacag tgttctcctg ccaaaacctc
    57841 ggtcataagt cacaatatac ataaaacatg aaaagctgtt ttttgaaatt atcccttgtg
    57901 actcagagtt agacggcagg ctcacaacct ctccactaaa cgatacttac attgatcctt
    57961 tgaacacacc gctgtttttg atgaagtaat ccacacctga atagatagta aagatcagac
    58021 aagcataaag catgatttga tctactggaa taccgatcag gctgaatggg atattattga
    58081 taaacagcaa gataatagca accatttgtg tagccgtctt gacttttccc ggccaagctg
    58141 cagccatgac ttctccatgt tcgacaagta gtaaacgcaa gcctgtgacg gctaattcac
    58201 gacagacaat gatcgctact acccaaccag gggcctttcc ttggtcaacc aacatgataa
    58261 aagcagtcat aactagcatt ttatctgcca acgggtccgc aaacttgcca aaattagtga
    58321 caaggcctcg cgcacgggca atttttccat ctaaccagtc tgtgatacta gctaaagcaa
    58381 aaataactgc acctactagc tgtgtgacag ccagtgtggt gtctcctacg ttaaattgtc
    58441 cccaatctaa aggtaaacct acaaccaaaa tgaaaatcgg gatcatacaa attctaagta
    58501 cagttaattt atttggtaaa ttcacactat cgactccttt cttccctatt ctacgtgact
    58561 atcagcgaag tttccaccga tattatttac ttttccaaat gaatttattc aaaggagtat
    58621 ttttattgaa attgatcttt ttgaattaac gaagaaggac cgcgacacag atttgtcacg
    58681 atccttcttt tttataccta caagtaaaca gatgcgtaaa ctaatttata cgatcattct
    58741 gcgtattgaa gagtaaggtt cacatttttt ggactctgat tgttttcccc tggattaact
    58801 ggtacggatt ctccattcgc tttgatcgtt gcattgcttg ctgcaccaat cgtgatggtc
    58861 gcatttgttg ctgtttccgg taacacggta ctctgtgttt catttgctgc cagtgtccct
    58921 tgataaacat aggcattgtc tactagcaca cctaaccata cacgattgac agcagtaaat
    58981 tcaagggtta caggcttggt agcgtctgtg atatttactg cgatggcact gccagaatct
    59041 tctcctgtag ctattgccat tttcttttct tcacttgatt ttgttgttga ttctactgta
    59101 gaagactctt tggtctgcgt gctttgctct gaggaagagg actcctcgac tgatccttct
    59161 actttaagcg aagaagctgt gtctccgatt attggatcag cttgacgatc ttgccaagtc
    59221 atatagccca cgacaacgac aatcgccaaa gcaaccaatc ctaataaaat gacaggaaga
    59281 cttgtccaaa agcgacttgg atgcgattct tcctgatgca ttgcttttct agaagtactt
    59341 actgtttcag gctgcggacg ttcagggacc gatcctgtca atttgctttt cccatcaaaa
    59401 acatcgacta aatggtctcc atcttctcct acagcttcag cgtattgccg aataaatgcc
    59461 cgcacgtaaa atttaccagg caattggtca aaatcatcat tgtcgattgc ttccaaataa
    59521 cgtttttgaa tttttgtaat ctgctgtaat tcatctaaag atattttttt attcaggcgt
    59581 gcttgccgta atttttctcc gatggtttca aaagccactc gttcatcttc tccagtctgt
    59641 ttgattctcc gaagcatctg ctgttgcaac gaaagacgtt atgtttgggt gctgtgacaa
    59701 aagtcatgtc acagctcctt ttttccgaat aaacattgtt ctcctgccaa ctcctcggtc
    59761 acaagtcaca atatccaata aatataagaa gctgtttttt gaacttgttc cttgtgactc
    59821 ggagttaaac ggcaggctca cgacctcttt cttaaacggt gttcaatcag ctgttcctcg
    59881 gtattagctc aaaaaccggc aaaatataag gagatatttt tccgtatgtt tctctaatac
    59941 tcaggtcaaa acgctgattt cacaacctct tccttaaacg gtgttcaaaa gcttgcatct
    60001 gcggtaataa gtccaaccaa gttaaaaaca ttaagaagct gtttttactt ggctgttctt
    60061 attacttgat gcagggcagc tttttcacaa cctcttggta cacggtgttc cagaagtagc
    60121 ttcttcggca ataagccgaa atatcacaaa aatttgagaa gcaattttcg taaattcctt
    60181 cttatttctt gaagctgacc acttctgtca caacctcttt gattacttcg tttgatttta
    60241 ttttaatata agttgattaa aagagagcat gatttgtttt attttctcac taatttttcc
    60301 aacacaacta agaataccat aaaagctgat tttggaggag gttcctacta caagtctaaa
    60361 acgaaattta agacttttcc tcataaaata ctggtttatt ttggtctcat gtaaaactcg
    60421 ctgaaggcct cttcacttat aaatgcttcc ccagctgcca gtacgtcttt catttggatc
    60481 gaatcgatga tttcaggaag atcaaataaa gttcgatcgc caaataaact ttgcgtaaat
    60541 tgattggcaa tatattcgat cgaatttaat gattggaaat attgtccaag cattttcttc
    60601 ttcagcaaat cgagatttgt ttctgacact tccggatcat cagcgaatcc aagaatgatt
    60661 tctttgactt tttctgctgc tttctctggt tcgtccgtat ctccgctgaa gtccgcaaag
    60721 tgaaattcac gatccaagct gaattcaaaa ccaaagctgt catcgataat tccttgattg
    60781 tacatcgcta gatagtttcg agaagtattg cctaaaatca tttggaacaa cagattgatt
    60841 gctgttttat agcgtaacag ttctgttcct tcttgcggca atgtgtctaa tcctttaata
    60901 ccaagtacaa atttatctcg tgtaatggct gcttccaatg cactttgttt gatgatttct
    60961 tttgtgtttt cagggaaata acgtacaatt tcttgctttg gagggaaatt ttttgcttct
    61021 tggttttccc gaataagttt catcaatttc tcaggctcca tcttaccaac tacaaataaa
    61081 accatattgc ttggctgata aaacgtccga tagcacgtat acaagtcttg agctgtgatt
    61141 ttgtcgatac tttcaaccgt gcccgcaata tcgatatgca atgggtgtgt aggatacaag
    61201 ttatttagta tgccaaaaaa catccgccag ttagggtcgt cttcatacat ttggatttcc
    61261 tgaccgatga ttcctttttc cttgtttaca gtttcttctg tgaagtaagg tgcttgtaca
    61321 aaatcgatca gagtcgtcag attcttttct acctgatccg tcgtagaaaa cagatagctg
    61381 gttttcgtaa aacttgtgaa agcattggcg gaagctcctt gtttcccaaa taattgaaag
    61441 acatcaccat cttctttttc aaacaactta tgttctaaaa aatgggcaat tccatctgga
    61501 actttcacct tttctttttc accataggga ataaattcgt tatcgatcga accataattc
    61561 gtactgaaca aaccatatgt cttgtgatag tcatttttag gcaacaaata cacggtcaaa
    61621 ccgtttggca gtacttcatg ataaagtgtt tcattgattt gctcatattc tgttttattc
    61681 atttgcattt cctcctgcta aaaagaagat tgcctgcaat tcgatttgct cagctacttg
    61741 ttgtatctct ttgatcgtta cgctctccat acgtttcaac cattcttcat cagataattt
    61801 tgtttccggc agccagctgt ccaaaaaaga agcttcgatt gccgcttgcg gagagtctag
    61861 agaaagcaga tattggtttc tcagcattgc ttttgtctga gacagttcca actctgttat
    61921 ttcaccattt cgcaaacttt ctaattgctc gtgaatcaga tgaagtactt gatttcggtt
    61981 cttttcatcg ataccggttt ggacactcat gaatcctcgg aacgtatcca cgctactaga
    62041 ggcataataa gctagacttt ctttctctct gacattcatg aaaagtttag agtgaggaaa
    62101 accgccaaat aaaccgttaa agaccattag cgcaaaacgt tctggttcat cgtaatacac
    62161 atttgtctga taagctaggt tcagctttgc ttgaacgatt ggctcacgta cttgtcgttc
    62221 cttcacgata ttcacttgag gttgggtata aaacagatct ggataaactg tttcccgcga
    62281 ctcaaatggt aattgcccaa ctgcttcagc tgctttgtcc ggatcaacat cgccgacaac
    62341 aaaaatgtcg atttgatcat ttgccatcat ttcttgatag taggacgcta gcgaactagc
    62401 agtgatcttg tccaaatctt cgactacgcc caaccctggg atcttttgtt ccgggctgtt
    62461 ttcaaaataa agttcttgca aggcatagga agcaaaagtt tgtttatctt ccttcaaact
    62521 ttccaaatat agacgcagat tgttcttttc caagtcaaac gtcaactgat caaactgatg
    62581 atttttaata tttggataaa ataaaacctc ttttaaaaaa tctaccgctt gagaaaaaag
    62641 gtttggatca ttgacatatt caccattcac aaaactgatc cctgcgttta gccaatgtaa
    62701 atttcctttt tttctaactg ataatccaaa gcttgcgcca taaagctctg caagttgcgc
    62761 acttaacttt gtctgatccg aataattcaa actatttgtt tccaacatgc tgctgagaag
    62821 tgaacgtttc gtgatgactt cttgttgcag acgcgcagta aaacggataa aaatccggat
    62881 cgttttgtat tgttttgttg gtaagacatg aagattcacg ccttctgcca attgatacac
    62941 catatttata tgctcctttt cacagttgat tgcccgctta ctcttttaat gggtcaacct
    63001 gcctttttta cttattcctc tgcttgaaat ttataagttc aggcaattcg ccgttttttc
    63061 taaatgatgt tacactttat agtatagcat agatgttttt tatcaaaaga aacagacggc
    63121 taaaagcgta tattgttttt ttatttttta tttttcgata tactaaagac aaataaaaga
    63181 agggagggtc attcatgatc aaagaattca aagagttcat catgcgtgga gatgtcttgg
    63241 atcttgctgt cggcgttgtt attggtagtg cgtttacaag catcgtaaac caagtggtgc
    63301 aaggcttgat cacaccacta ataggttggt ttgtcgcaat gatcacaggt acttctgatt
    63361 tagaaggagc actttcaatt cttgactggt cgccgacaaa aggcgtcaca tttgcgtttg
    63421 gtaacgttat tagtgctatc attacatttc tgatcactgg ttttgtctta ttcttagttg
    63481 tcaaagcggc aaaccgtgcg aagaatttac gctccaaaga agagcaagtg gaagtggaag
    63541 aaactcctac tgcagaagat tatcttagtg acatacgcga tcttcttgcc aaacaagtgg
    63601 cagaagacaa tacacatcca gtagagcaaa caaatctttc cgatacttct aaataataaa
    63661 gaatctaaaa aaaagaaagc cgattttcag tgtcggcttt ctttttttag attcttaact
    63721 tgctacttgt tcctttttca tgtcgatatg tggaatatca tcttccaaat acacatctga
    63781 gattgccttg aatccaaacg actcataaaa agcttgtagg tattcttgtg cgccgatcac
    63841 gattggtttt tctggaaaat ttttctggat catgttaatc gtttcttgaa caatctttct
    63901 tcctaaacca tctttacggt tgtcctgatg aacaaggaca cgtccaaaat ggatactctc
    63961 cgcttcttca tatactcgcg tgtaggcaag gatcttccca tcagtatctt gaaaaaacgt
    64021 atgccaagct tctccatcaa tgtcatcaac ttcttgataa ggacactgtt gttccacaac
    64081 aaaaactgcg attcgttctt tgacgatcgc gtaaaactct gctgttgaca attcttcaaa
    64141 tttctttacc tgatattcca ctaagcaaac gccccctgct tttttattct tagcataccg
    64201 attcgcacac aaaaaagcaa acgaacctta cgaatctcag gctcgtttgc tttttaaact
    64261 gcttcagtta aaaattcgat ctcaactgtc cgagtaagta catctgaata gctgtaagat
    64321 actcgttcaa aagaattttc ttcaggatcc aaatcaacaa cgaatactga aggataggtt
    64381 tctgttaaaa cgccgcggcg ttctgtttga cgctttcttc ctgtctgagc aaccaacatg
    64441 attgggctgc cgatacgacc ttctaaatct ttcttgattg aagctaaagt tgttggcata
    64501 cagttcacct ctactatcaa ctataccaca tatttttaaa attttcaagt ttaccataaa
    64561 aaaaaaagaa atgcaataaa aataaataag aagctcatta agatttttct aaattattcc
    64621 tcattataaa atttcaagtg tttttttatt ttgagtttta ctctcccgta agcgctcatt
    64681 acttgcttgt gatccattgc taaacattca gccatgtcta caaaatcaac gccttgcata
    64741 taataatgaa aaattttagc ttctattttt gaaaactgga tttcgcaatt ttcgattgct
    64801 tcttttaata aaagatgctg aattgctaaa ggttcttgca atgtgatctc tgctaaaaag
    64861 tctggtcctt ctgtctctat tttttggtcg attgagactt catctttttg atcacgacgc
    64921 ttcagcgcgt tctgcttcct caacagagaa tagatttgat tgcttataac gcttttataa
    64981 taacttccaa agctaacacc tttgcttttt tcgtaagttc tcaatgcctg atataaagcg
    65041 atccttgctt cttgttccca atcctcagaa acataatttc ttaaataata ggtgtttttc
    65101 aaacgtagta aaagtggaaa atatttttga tacagggcag caaatgcttc ttcgtcacca
    65161 ttacgtgcag cgcgcaataa ctcctcagac ataaaataat tcctccataa attcgtttat
    65221 ggaggaatct tatcatcaat gattcatcga actgattaga acgatatgtt atttattttt
    65281 tctcattaaa tcgtccaatt tttgggacaa tttttttaac tgctcttcat tccatggaga
    65341 attacgtcgg aaatcaataa aatgcatatc tttattttct tgggctattg ttttttccgt
    65401 tttttttatc gtcttatata attcataagc agaagttcgt aatgctcctt gggaaaagat
    65461 catccactgt tctgctaaat cgcttgtcgc cactgtcact tgtgtcaaac ggtcattcag
    65521 ctgaccagcg attctctcga tataactgtc agccgtttcg tcttctttcg taaaaacaac
    65581 atccaactgg tatttcttat aattttgttg gatgcccgga actagttggg catcgaagac
    65641 aacgatgact tccattcctt catatttcgc ataatttgat aaacgatgta aaagagcttc
    65701 tcttgcatcc gccattttgt cctgcttttt aagctggaca agttccggcc acgaaccaat
    65761 catgttgtag ccgtctacaa tcaacagctg ttttttcatg gtctactccc cctgacgttg
    65821 ggaaaaagcc tgatacataa gcaaaccagc agcaacactg gcatttaagc tctggacgtg
    65881 cccggtcatc gggatcgtca gcaattcatc catttctttt ttcaatcctg gactcattcc
    65941 tttgccttca ttaccaatga ctaaagcaat tgatcctttg gcattccatt tttggaagtt
    66001 tgtgccggtc atatctgtgc caaataccca aaatcctgtt tctttgagct gttgcacagc
    66061 ttgtaccaaa ttcgtcacgc gtgcaacagg gacatgttcg actgccccag tggaagtctt
    66121 tgttacgata ggtgtgattc caactgctcg gtgttttggt atgatcacac catcgacgcc
    66181 acttgcgtct gctgtccgta aaatcgaccc aaaattgtgt ggatcttcga tgctatccaa
    66241 aatcaaaaag aaggggtctt cttttttctc ttttgttcgt tcaatcagtt ggtcaaggga
    66301 taaatattca taaggtgtaa tcgcaagaac gactccttga tgcacgccgt gatcgctcaa
    66361 agtttctaat ttttgtttag gaacccattt gactggcaca gcttgttcac gtgcgatttc
    66421 tttcagttct tctacttttt ctcctcgtga atcttcttga agaaagagtt tattccctcg
    66481 cccttgttgt agcgcttcta ctgcggcatg gtgcccaaag acgaaattat cttctaatgc
    66541 ttcttcattt tgatcagaaa ctgactgatt tcgtccagtt tgctttttat ttgaatatct
    66601 attttgtttt ttgtcttcaa atccacgttt cgattgatgt ttgtttgttc tttctttacc
    66661 catttttttc accaactttc tgaatacacc agcggatcaa ttcttccatc cgctcggttt
    66721 gttttgtcaa atgcagatag cccatgagcg cttcgaaccc tgttgcgacc cgatacgtcg
    66781 taacatcagc attttttgcg ctcgtatggc ttttagcatt tcttcctctg cgataataaa
    66841 gttcttcttc ttctgtcaaa agatgttctt ccagcatttg ctgaatcaaa aaggcttgtg
    66901 cattcgcaga aacataattc gttgccgcac gatgcagctt attgggtttt gtttctcctt
    66961 gatcaatcag gtggtcacga acatagattt cgtaaatcgc atctccaaca taagccaagg
    67021 ctaaaccgtt caattgtgtg taatctctca tgcttctctt ctccatcggg ttccttgcgg
    67081 tgtatcttct aataagatcc ctttttcttt caacaaatca cgaatttcgt cgcttcggac
    67141 aaaatcacga ttgcttcttg cttgatttcg ttcttcgatc aattgttcaa tctcttcatc
    67201 taataactct tctgctgtaa ataaaatacc gaagatcgaa agccattgcg agaataaagc
    67261 ttctccttgt gccaagacag cggcagaaac tttcggctgg tctagataag tgttcagcca
    67321 cttagcaagc tcatagacca ctgtgatccc atttgctgca ttaaaatcat cgtccatttc
    67381 ttcgatgaat cgctgttcta aattttctaa caaagcgatt ttatccgcat catctgccaa
    67441 attctctgag gcagtttctt ggcggaattt caaattgtca aacgtattct tcagtcgttg
    67501 taaattggtg gctgcttctt tcatcgtcgt ttcactgtag cggatcggac gacggtattg
    67561 tgtggtcgcc atgaagaaac gcaagacttg tggatcaacg tttttgatca tttcatgtac
    67621 agtgatgaaa ttccctagag atttactcat tttttcatcg tcttcgccaa tcgttacata
    67681 gccattgtgc atccagtaat tagcgaattt tttccctgtt ttcgcttcac tttgtgcgat
    67741 ttcattttca tgatgaggaa attctaaatc ttgcccgcca ccatggatat cgatcgtttc
    67801 tcctaaatgt tttgttgcca taacggaaca ttcaatatgc caaccgggac gtcctttgac
    67861 ccatggtgaa tcccaagaaa tctcgccagg ttttgcttgt ttccataaag cgaaatctaa
    67921 tgggtcttct ttttgctgct gttcttcccc tgtacgctga cttgctccga cttccagttc
    67981 atcgatggat tggtcactta atttcccata attttcaaat ttacgggtac ggtaatacac
    68041 atcacctgaa gattcataag catagccttt ttcaaccaac acttgaataa atgctaaaat
    68101 atctggcata tgatccatga ctcttggatg cagtgtagca ggttcgacat tcaacgcttt
    68161 cgtatcttct tcaaatgctc ggatgaaacg atcagcaact tctggtgctg taatacctaa
    68221 ttcgtttgct gtacggatga ttttatcgtc tacatccgtg aaattcgata cgaaatcgac
    68281 tttatagcct cgatattcaa aatagcgtcg aattgtatcg aaagcaatgg tgctacgagc
    68341 atttccgata tggatataat tatacacagt cggtccgcag acatacatac cgacatgtcc
    68401 cttttgtata gggatgaatt cttctttttt tctggtcaat gtattgtaga tttttatcat
    68461 tctgatctcc tcactttttc tcctttgatt cgaacgactt ttgctggtac tcctaccgct
    68521 gtagcgtcgt ctggaacatc tttcaacaca acggcacctg caccgatttt ggcgtttttt
    68581 ccgatcgtta ccggtcctaa tatctgcgca ttcgcagaga gcatggctcc ttgtttaaca
    68641 gttgggtgtc ttttacccgt ttcttttcct gtgccgccta atgttacgcc atggaataaa
    68701 atcacatcgt cctcgatttc tgcggtttcg ccaatgacga ttcccattcc atggtcgatg
    68761 aacacgccag ttccaatcgt tgctcctgga tggatctcaa caccagttag gaaacgccag
    68821 aattgagcat tgatcttcgc caataaaaag agccggtgct gatataaaaa atgagagaaa
    68881 cgatgccaaa acaaggcatg aaaaccaggg tatgtcaaaa cgatctcagc tgtcgaacgt
    68941 gcagccggat cgtttctctt tgctgcatca atcgctcggg taaaccaact catgactttc
    69001 cactcctttc gtaagaattt tatgtaggaa atcatcttct tataaagaaa agaagcgcct
    69061 tttaaataag tttccttatc aaaagacgct ttccgcgtgg ttccactttt cttcataatc
    69121 aatgattatc tctgacagct aacgcctgtt atacgttctt ggctactttg tttcctataa
    69181 aacagttttt cctgttttct gtgtttcgcc aagaccactc ccagaggcat ttcggcaacc
    69241 attcattgat accttgcacc acccggtatc tctcttgtaa tgatcagctg cttacttttt
    69301 tctgttcatc gtgtttagtt cagtacttga tttaaatgtg ctaatgattt ttcacgacca
    69361 agcaattcga tcgtttcagg caattctgga ccatgcattt gtcctgatac agctacacgg
    69421 attggcatga aaagattttt tccttttacg ccagtttctt tttgaacagc tttgatggca
    69481 gctttgacag ttggagcatc tactacttcc atttgttcta gctgtgcttt gaatgcgtgg
    69541 agaacagtag gaactgtttc accagcaagt acttcttttg ctgcttcatt caatacagga
    69601 tgttcattga aaaatagcgt agacagatca acgatttctg cagcatagct catttgaggt
    69661 tgatacaggc taacgatctt cttcacccat tcgattgtct tttcatctgg gttttctgct
    69721 acacgtccat cagcgattag ataaggcaga cacatgtcag taaatgcatc tagatccatt
    69781 gctttgatgt aatggttgtt tacccattgc agttttttcg catcgaaagc tgcgggtgat
    69841 ttacttaggc gttttggatc gaacattttg atcaattctt ggtgttcgaa gatttcgtct
    69901 tcgcccacag gtgaccagcc caataatgca ataaagttga acattgcatc tggtagatag
    69961 cctaattcgc gatattgttc gataaattgc aagattgatt cgtcacgttt gcttagtttt
    70021 ttacctgttt cactgttgat gatcaatgtc atatgtccga aggttggtgg tgtccagcca
    70081 aatgcttcat agatcatcag ttgttttggt gtattggcaa tatggtcatc tccacgtaaa
    70141 acgtgagtga ttttcatcaa atgatcatcg accgcaacag caaaattata agttggcata
    70201 ccatcgcgtt tttggatgac aaagtcgcca ccgatattat cggattcgaa cgaaatagcg
    70261 cctttcacca tatctgtaaa tgcgtattct gtattgcgag gcacacggaa acgtacaaca
    70321 gattctagac cttgtgcttc tttttctgct tgttcttcag gtgtcaagtt cgcacatgtt
    70381 cctgcgtaat gaggcatttc tcctcttgcg cgttgtgctt cccgttctgc ttctaattct
    70441 tcttctgtgc aatagcattt gtatgctcga ttgctagcaa gcagctgatc aatcagcggt
    70501 tgatagattt ctttacgttc agattgacgg taagggccgt attctccagg attttcagga
    70561 gattcatccc aattcattcc caaccaagca aggttttcca actggctttt ttcgccatct
    70621 tcgatattac gtttttggtc agtatcctca atacgaataa taaagtctcc atcattgtgg
    70681 cgggcaaaca aataattgaa taatgcagtt cttgcatttc caatatgcag gtgcccagtt
    70741 ggacttggtg catagcgtac gcgtactttc gtcattttct tcctcttctt tcaaactaga
    70801 ctttgactaa cagcaaaaat tccgtcagtt acggcttctc aaatatcatt tatttaaagc
    70861 cactcagcac aaattttacc ttttctaagg taaatagtaa agccaactgg ttgaatttcc
    70921 ttaccagttg gctgaatttc ttttttattt tgattgttta gtctttttct ctgtctcttt
    70981 tttattgtcg attcctcgtc ctgcatgtgc aggtttagca aagatcatgc gtccagcagc
    71041 tgtttgaagg gcacttgtta caacgacttc gatacgttca ttcatgtaat gctgtccatc
    71101 ttctacgaca accatcgtgc cgtcatcaag gtaggctact ccttgttggc gttctgtccc
    71161 ggcttttact actagaacat tcatcgtttc accagggatg acgactggtt ttacggcatt
    71221 tgccaacgca ttgatattaa gaacaggtac attttggaat tcagagactt tattcaagtt
    71281 atagtcattg gttacaatga caccatctaa aagcttagcc aatttgatca atttgctgtc
    71341 tacttcactg atatcttcaa agtctccatc gtacatttcg acagatatac cctcttcttt
    71401 ttgcaaggca tttaggatat ctaatccgcg acgaccacgc acacgtttca aactatcccc
    71461 tgagtccgcg atgtattgta gttcgtaaag aacaaaatta gggatcatca aggttccttc
    71521 taagaatcca gtctttgtaa tatcataaat ccgaccgtca atgatcacgc ttgtatccaa
    71581 gattttatat ttatggaaat tttctcctga ttttcgttct aacagttgac tctcaacttg
    71641 actagctgtt tcttgctcga tttttttgct tcgtgaacca aaaactttct tccattcttc
    71701 gattcgtgtc gttcccattc tcaatcccag atagcctaag atgatcatca gtaaaatcgg
    71761 caatacacta ttgacgaatg gaatttccat attgtaaaga ggggtcgaga tcacaacacc
    71821 taaagtcaat ccgatgatcg caccgatcgc accgaagaga agataagtca agctgacctc
    71881 acttagtttt tgttctactt gtttgataat agctgagata tgtttggcca acagcaaaga
    71941 taataaaaag aaaataagtg cgcctaacag gctgttggta aatgtattat tcagccatcc
    72001 gtttgactgt tgaccgattg cctgccaagc tgagggtaaa aatgaaatac ccaagcttgc
    72061 gccgacaatg atcatcagca aagtaatgac acgtttttgc atcgtttttc ctccgtttcg
    72121 acaatcattt attagttagc ggaacacacg cttcaacgtt tcagccaaag ttgctactcc
    72181 aactatctcg attccttttg gcgcttccca gttacctaag ttgtttttag gtaggtatac
    72241 ttttgtgaag ccgagttttt ggacttcttt gactcgttgt tcaatatgac tgacacgtct
    72301 gatttctcca gtcagtccaa tttcaccgat gaaacattcc gttggctgtg ttcctttttc
    72361 tttatagctt gaagcaatac tgacagcgat agctaaatca atcgctggtt catttaattt
    72421 taccccacct gcagctttta agtaagcatc ttgattctga agaagcaacc cagctctttt
    72481 ttccagcact gccatgatca gagatacccg attgaaatca agacctgttg ttgttcgttt
    72541 ggcatttccg aacatagtag gtgtgactaa tgcttggatc tctaccaaaa ttggacgtgt
    72601 cccttccatt gccacaacga tagcagagcc agttgcaccg tctaggcgtt cttctaagaa
    72661 aatctgtgaa ggattagcga cttcttccaa tccatgctca tgcatttcaa aaatcccaat
    72721 ctcattcgtt gagccaaatc ggttttttac tgctcgcaaa atccgaaaac tatgatgttg
    72781 ttcaccttca aaatataaca ccgtatccac catatgttct aacattcttg ggccggcgat
    72841 cgagccttct ttggtaacat gaccgacgat aaaaatggct atcccatttg ttttagcggt
    72901 tttgagtagt tctgcagtgg tttctcttac ttggctgaca cttcctgcca cacttgtgat
    72961 gtctggctgc gtcatcgttt ggatggaatc aatgataaca taatcagggg agatatgttc
    73021 gatggcacga ctgatttcgt tcatatctgt ttcagcgtat agataaaatt ctgtgttgat
    73081 acttccgagg cgttccgcgc gtaattttat ctgctctgcg ctttcttcgc cggatacata
    73141 taagactttt ccgcctatgg ctgctaattg ctgagaaact tgtaacagca aagtggattt
    73201 cccgatacct ggatcgccac caatcaagac catagaccct ggcaccacac ctccgcctaa
    73261 cacacggttc agttcttcta attttgtttt gatccgaggt tcttttttag ggacgacgtc
    73321 tgcgattttt gttggttttg ctttttctcc tgtcaaactt gtccgagttc tgcggtccgt
    73381 tgtatcttgt tcgatttctt cgaccatcgt attccatttt ccgcaatttg ggcagcgtcc
    73441 caagaactta ggcgacacat acccgcaatt ttggcaaaca aattgtactt ttgatttttt
    73501 tgccattgta ccgcctcctt ttatcctaat catgagacat taaatcaagc ttaagtatct
    73561 ttaacgtttt atttactgga agaaccaaat ccgccttgac gttgagcagt cgtttgatct
    73621 tgatctgctt ttaaaaacgg caaaaagatc ccttggccga tacgctcgcc ttttttgatc
    73681 actacatcct tgaaaccaaa gttggtgaat tggaacatga tatggccttc atttgcctca
    73741 ttattgtaat aatcactgtc aatcacacct actccgtttg tcaacactaa aaaccgcttc
    73801 aacggattgc ttgaacggtt agcaagctgc aaaaattcat cttctcccat gtaagctttg
    73861 attccagtag gcacgagggt tggtttcaat tgtttttcat tttctgatac atcttttttc
    73921 aatccatctg cgactgtttc caaccccttt ttccagcctg ctttccagat acttggaatc
    73981 acgacctctt ctgctgcttc aaaatcatag ccagcagcat gatgtgtagc gcgctgcggt
    74041 agattgatat tttgatcttt atatttagaa ataacttcaa atcctctttt tctcaccggt
    74101 tttcctccct aaataaacta ctcctattct aacatatccg aggctgtaaa agactttctt
    74161 tacaaattct tcaagaaatt ctgctatctt aaagtaaacc attaattcgt tctttttcca
    74221 aacgactgca agttgtacaa aaaaactatt ttttacatga ctttactcgt caaaacaagt
    74281 agaatagaac gaaattaatg agtggatatt tgattgaggt gtcacatgcg taaagaaatt
    74341 aaaaatgcaa aacgaattat tgtcaaagta ggaacaagta cattgattta tcccaatgga
    74401 aatatcaatc ttgcggcaat cgatcagtta gcttttgtcc tttctgatct tagaaatcgg
    74461 ggaaaggaag tgatcttagt ctcatcagga gctgtaggcg ttggtatgca taaattacat
    74521 ttgtcagaac gtccgacttt gattcctgaa cagcaagctg cggcggctgt tggtcaagcc
    74581 gaactgatga atatctataa tcaaagattc agtgtatata atcaacagac ggcacagatc
    74641 ctcgtgacaa gagacgtggt agattatcct gaaagtcgta aaaatgtgag gaatacattg
    74701 gaacagcttt tgattatgga cacgatccct atcgtgaacg aaaacgatac tgtagcagtg
    74761 gatgaattag atcatctgac aaaatttggc gataatgatc agctgtcagc catcatggca
    74821 aaacttgtcg cggcagacct tttgatcgtc ctttctgata tcgacgggtt ttattcagat
    74881 aatccgacta caaatcccga ggctcagatg tatcgctata tcgataaaat cgatgaaaag
    74941 attctggcac aagcaggtgg tgctggtagc acatttggaa caggcggtat gcagagtaaa
    75001 ttaaaagccg cttctaggat atttgaagca aacagcgcaa tgattttagc aaatggaaaa
    75061 aatccggcaa ttatttttga tattcttgca ggaaaagaag taggtacttt atttaaggag
    75121 gacttgaaat gactgacttg atgcaattag gacaacaggc aaaagatagc gcgcaacaac
    75181 tagcacttat gcctacaaac cgcaaaaatg agctacttgt tcaaatggca caaaccatca
    75241 aaaagaatca acaagcgatc attgaagcaa atcataaaga cttagaaaaa gcagtcgaaa
    75301 acaatatcag tgaaacgatg caagaccgct tgcagctgac acctgagcga atcaatgcca
    75361 tggctacaga gatcgaaaaa attgcttcgt tagacgatcc tattggaaaa gtagatgaga
    75421 tgtggacgaa caccgacgga ttgagaatcg gcaaaaagcg cgtgccacta ggcgtgatcg
    75481 gcatcattta cgaatctcgt ccaaatgtca cgacagatgc agctagtcta gcattcaaat
    75541 cagggaatgc cgttatcctt cgcggtggca aagaagcatt cttctcgaat caattattag
    75601 tccaattatt gcagcaagta ctggtcagtg ctggcgaatc tccttatgcc atccagtttg
    75661 tcgatgatac ttctcatgaa actgcaggac agttgatgcg attgacagaa tacttagatg
    75721 tgctgattcc tcgaggcgga gcaaaattaa tccaacgagt caaagaacag gcaacggtac
    75781 ctatcattga aacaggtaca ggaaataatc acgtatatat cgataaagaa gcacagttat
    75841 ctatggcagt gaacatcatc gtcaatgcaa aagcttcccg tccatctgtc tgtaacgcgg
    75901 cagaaacatt gctgatccat tctgagatcg cacctttttt cttgccagct attgaaaaag
    75961 aactggtaga acacggggtc tctttacgtg cggatgctcg tgcgttagaa tatctagaga
    76021 cggctgcttt agcagaagac acagattggg atactgaata tctagattat atccttgctg
    76081 tcaaagtggt cgattctttg gatgaagcaa ttgcacatat caatcggcat aatactaaac
    76141 attcagaaac gatcgtgaca gatagttatg cggctagtca acgtttctta aatgaagtgg
    76201 acgcggcggc tgtctatgtc aatgcctcca ctcgttttac agacggatcg gtatttggtt
    76261 ttggtgcaga gattggtatc tctactcaaa agttgcatgc ccgtggtcca atggggttaa
    76321 atgaattaac ttccacaaaa tatatcattt atggcgatgg acaaatccgc gaataatgtt
    76381 tcgtgtgaaa cattattccc gccttttgcc ttttttctgt aaaggttcta tccaactaga
    76441 aaggtgtcaa tatgtttgaa attttaatga ttttttttat ttaccttatt tctctgaata
    76501 tcgctgcttt tctgggagtc ggtattttat cccttttctt tcaattcaaa aaacgaagca
    76561 tagggagtca acgggaaaaa tggtcgcagt attttgacaa aatcgggcaa aaagggctgg
    76621 ttacacgctt gcacattagt tacatggttg cattatgctt attagcgaca atcaattact
    76681 attctttttt cgatcattca atcgcttata cgattacgct actgattgct gggatttttc
    76741 acttatctta taaatatcag ctgaataaaa accacttgaa tcggactttc cgctaaaaaa
    76801 tatccgtacg ataagtagag tgccttgaag atcggcaaaa aactgccgga ctttttagag
    76861 gctgtgacaa agattttgtc acagcctctt tttccatata aacggcgttc gcctaccagc
    76921 tgcctggtaa atctgtttcc tcttcgttaa gaagcgaaaa tccgtcaaat gtttcgccat
    76981 cataataacg aagcagctca tccatggaca agttcatcgt tttttctttt tcttcttccg
    77041 ctgattcagc cagtagctgt tcccgataca cctgatacat accagctatt ttttgctgca
    77101 tcgcttttct agtttcacct tccgcattga ttattggcaa ttctttgata tagccacgat
    77161 aaatcaaccg atcatctgaa aattcaatgg gtaattcaac gagtgtcaac ccgacttcct
    77221 gaaaatattc ttccagcatc tattatcccc ccattctttt tcttaaatga attttagctt
    77281 acctactgaa aattttccag tttcattatt ttgagaaaaa aagggaatgt gacaaaaatc
    77341 gtgtcacatc ccctttttcc gaataaatgg tgttcttctg ccaactcctc aatcataagt
    77401 cacaatattc aacaaacatg agaaactgtt ttttgaaatt gttccttgtg attcagagtt
    77461 aaacgacagt ctcacaacct cttggtaaac ggcgttcaat cagctgaccc tcggtattag
    77521 ctcaaaaaac ggtaaaatat gagaagctat ttttccgttt tgtttctcta atacttagga
    77581 taaaacgctg attttacaac ctctgttaaa cggtgttcaa tcagctgtcc ttcggtatta
    77641 gctcaaaaaa cggcaaaata tgaggaacta tttttccgtt tgtttctcta atactcagga
    77701 caaaacgctg attttacaac ctcctgataa acggtgttca aaagcttgca tctgcggtaa
    77761 taagcccaac caaacgaaaa atatgagaag ctatttttgt ttggctgttc ttatgacttg
    77821 atgcaggaca gctttttcac aacctctgat ttcttattct tcttcatttg tagcaaaata
    77881 attacggtga taaatgatac aacatacact gataagaaca atggcacctg caaaataaaa
    77941 cgcatagctt tcaccaatat gttcaccaat cacacctgca ataaatggtg ctaaagctcc
    78001 accgaaaaag cggacaaaac tatagctgga cgaagcaacg tttcgttgca gacctggtat
    78061 ttccatagca atcgtcgtca acagtgtatt gataattcct tggaaaaatc ctgctaacac
    78121 aatgctgatc ggtacaagga ctggcataga agttccagct cctaataaca gcaaacaaat
    78181 aatgaataag acaaatgctg ctaaaattgt ccgataagtc gtaaacttcc gctcaagagc
    78241 cggtgcaacg aaaatcgaag caatagccag aagcacaccc cagccaaaaa atacaaaacc
    78301 gacttctaat tcagaatagc caatcaataa aaatggcgca tacgcaagta aagtaaagaa
    78361 tccgaaatta tataacaatg cgattagtcc aactgaacga agtttatgat tgcttaacgc
    78421 tttgacacct tcccaaaggc ctacttttct ctttggtttc tcagtttcag gtaaaagtac
    78481 cgctagggct ataaaaccgc aaaacatcaa aaatgctacc ccaaaaaatg gataacgcca
    78541 tgaaccactg cccaagaccc caccgactag agggccaaca gccattccgc agccaagtgc
    78601 tgcttcatac atcatgattg ctttttctgt gttaccaact aaaatactga cgatcgttgc
    78661 taaagcagta gagacaaata aagcattccc gacaccccag ccggcacgta acccaatcag
    78721 cattccgata ttcccagata atccgccaag accagcgaat acaacgatga taaacaatcc
    78781 tgtcatcaat gtttttttca aaccgatccg actagataag aaacctgtaa atagcatcac
    78841 cacaccagtg actaacatgt aactagtaaa taacagggtc gtttcagctg gcgtagcgtt
    78901 taactgtgca gcaatcgttt ttaagattgg gtctactaga cccactccca taaaagcgat
    78961 catacaggta gctgctacaa ctagcgctga acttttcccc tttgtttctt catttgtttg
    79021 ttcttgtata tctatttgat tctccaatat ttccatccct ttctctctat tagcatcata
    79081 catgatttat tttacatgtc aatatgcaca tgtaaaacgt ggaaacttta ctgtgatata
    79141 ataaagaaaa taagacgaga ggtaggattt ttatgaatac tttagcctat atattattat
    79201 gcgtgctttt atccaaacca cgttctgggt atgaattgaa gcagctgatc acaatttttt
    79261 gggaagccca tcacagtcag atctatacaa cgcttgccaa gttagaccag cagggttatg
    79321 tgaccgtttt ggacaaagac gagcactctc aaaaaaagat ctaccacttg actgatgaag
    79381 gacgtgctct tgtagaggaa tggatcaaag aggaaactcc cgctcctacg caaaaagatg
    79441 aatttctagc aaaaatctat gctttttcga cgctcgataa aacaacagct actggactgc
    79501 tattcactag agaacaacag ctgaacaaaa tcatgcaaaa aaatcaaaaa aaattgaatg
    79561 acctctcgct agacaagaaa caagaatttg gacgttatgt tgtgatccag cgcagaatta
    79621 tgctttgtca gcaggaactc caatggtgtc agcaagtaag agaacaaatg cagcagtttt
    79681 ttgagtaagg gataaacaga acctttctag aaatatctat tgaagagcaa attatcttca
    79741 ataaaagagc aatacagttg gaaaagaaaa agcgatccga acgacaggcc aaaacctatc
    79801 gttcggatca ctatttttct agaactgcat tcaagagact atgacaaaaa gcatgccaag
    79861 gccttttttc aaataacagt gttccatcat tcattacttt gaattgcttt tagcacactt
    79921 cttgaaagcg ggccaacgat gatcaactgc aacggtaaag cggcaatcac attcattttc
    79981 caagcattca tataagcaga gaataattga tcaggtattc cttgttccat gatcacaccg
    80041 aataaagaca tacatgtcac cattcctaaa accatcaagc atgaaatagt taagatcatt
    80101 tggaccttgc tttctggatt tactggtagt ttaaaggcaa tttttttcgc cagcacaccg
    80161 atgatgaaga catccaaaat gaaagccacc acgaatccag gcactagacc aatcaacaaa
    80221 cttgataaat gaagatcttg atgcagccat aaattatacg cgctcatccc caagaccatc
    80281 aaaaaacaca tcattgttgt aaaaattatt ccttcttttt tatttgtagg caatctgtac
    80341 cactccttta aatttgtcac gaaaatcatc gtagcacatt taaaaatttc tcgtaagtac
    80401 tttttttatt ttctgccctt ttatttcata aacttcatca gccgtacgct cgacaaagta
    80461 agaatcatga gaagtaaaca aaatcgttcc cggatatatt tgcattagct tctctaaagc
    80521 ttcgatcgtt gccatatcaa taaaattagt cggttcatct aacagcaaca cattacttgg
    80581 cttagtaaaa agcaaagcaa tcgtcagacg ggtcgcttct cccccactta atgtacataa
    80641 cggtttcgtc aaagtttcct gagcaaaccc taagtgattc agcaaactac ggacaagcga
    80701 ttctgaaaac tctgtttgtc tcatgacaaa acgaatgatg gattcttcag atgtcatttg
    80761 ataacccttt tgctgatata cttgaaagct tactttcgga gagagaagga ttccttctcc
    80821 ttgtttgcgg atatgttcta ataaggttgt cttacctgaa ccattttcac cgacaatcgc
    80881 gattttttta cctaaagaaa actgaaaatc accatttacc agtaatgttc tcccacttct
    80941 ttccaattgg acattttgtc ccatgatggg atagcggctg tggagttcaa gagattttgg
    81001 tactggaaaa cggatttgtt tcatctgctg cggcttggtt gtttctccta ttttttggag
    81061 tcttctctct aatgttttcg cattcttttg gatggctttt tgtacactgt ctttttgttt
    81121 agaggaagac aaccgatcca gtctgatttg ttgctttttc tttttactgg acactttttc
    81181 caacttttcc gcttgttttt tcttttcttg gatcgatttt tccaatcgtt ttttctcttt
    81241 catgatcgac tctgcttctc gtagctgagt ctttttctcc aattcctttt gagtgagata
    81301 ggcactataa ttccccgaaa actctcggat ttctccgtct tttacttccc agattttcga
    81361 tgctagctca tctagaaaat agcgatcatg actaacaaaa accagcgtac cataataata
    81421 acgaagctct tcaatcagtc gatcaatact ttttctatct agatgggttg ttggctcgtc
    81481 tagaagcatc ccttgttcat aagaagaaag aagacgtatc aactcgatct ttcgttcttc
    81541 ccctccgctc catttccgct ctgaagtttc ttccagtctt aactggaaat gactggctaa
    81601 ttccaaattt aggtcctttg cttcagcgag ataggttaat tgaggcaggt agttgaaggt
    81661 gatctctgtt tggattttcc catgatcggg aaaaagttca ccggctatta gtttgagcaa
    81721 agtcgattta ccgacaccat tttctcctat gatccctata cgatcttgct gatagacacg
    81781 aagagaatca atagatagtt ctagctggtt gccaaagctg acttgtagat ttgttatatt
    81841 tactgctaaa ttttccatat gttttacact cctatttcat gtaaaacaac aattatcgat
    81901 actaaaaaag agcagaaaaa tctgtttgca aaaaaactgc atcacatctt ttcctactct
    81961 gaacgaaata actatgacta aatcaccaaa tctgtcatag ctttcaccta ttctactgtc
    82021 gttcgaaaaa atggacatac tccatccatg aaattgttgt ttatacatgt cttttgaatt
    82081 tatttagttg ttattcaaaa gttcgaaacg taatttcatc gatgcagtca tttttccgac
    82141 ctcctttttt attaggttac cacacacgat tcaaaaaaag caatagctac tgaatagtaa
    82201 ctgaaaacct tttattcgaa catagtgatc ttttctggtg ctaaacgaac agactcgtaa
    82261 ccttcttcta ccgcttttcc tattgataaa ataataactg gaacataacg gtctttatcc
    82321 aaaccaaatg cctctgccaa ctgatctgct tcgaatccac caattggatt tgtttcatag
    82381 ccatgatcac gcgcaactaa catgaattgc atagccgcta agctagaatc gactttgact
    82441 acatcgttca tttcttctct tgaaaaactc ttgtaataag gaatgatcgc agctaattgt
    82501 tgatctctga cttcttttgg catcttccct gattcgtaag cttggttgta gatttcttcg
    82561 ccatattcgt aacattgcat atcgccaaaa atcatgacca ttgcagaaga agtatcattt
    82621 tgtctcgtat tgaaacggat caaaggacgc aagatttctt ttgcttcctc gctttcagcg
    82681 accacaaagc gccatggttt catattgaca gaagaaggtg cagtcgtcgc ttctttgatc
    82741 atttccagca tttcttcgtg tgggattttg tatgtttcat catatacgcg aacggatctt
    82801 ctaccagtca taattgttga aaaatcattt ttttgttcca ttattattaa cctctttcgt
    82861 ttctgttgtt atattgcaaa gttgggtatt caatttatct aaaagtgtta gaaattgttt
    82921 catttctaca tcgctgaaag ccggggatag cacggaacct gtatctttat ggtccatttc
    82981 acaatgcttg attttcttct gggctttttc tgttagcgct acatacactt cccggttgtt
    83041 ctgaggattt ctctgacgcg aaacatagcc atttgcttcc aataccttca gatgacgagt
    83101 aactgctcct tgatcaatct gcaacttttc ttgcaaactg ctttgtagca atggattttc
    83161 ttctttcagt ctcatcatga tctcgtatct agtaagactt ataccgatat tttcttcaaa
    83221 gatctggacg attttttgat cggctaattt gatttgatat aaaaggtgac taatctcttc
    83281 taaagacata atttcctcct ttctaataat tgactcgtca acgattgact tgtcaataat
    83341 agaataaaaa aagaaaaaag tcaaagaatc agctgtgtaa taaaaaaaac gctctcaata
    83401 gaaaagtata gagaaaagaa attttttgta gaatgaacgg aaaaaatgat aaagaaagca
    83461 caacgctaaa accaagatta ttgattctta tcaaactata gaagatagct cttctgcagt
    83521 agataatttt acaccgccaa aaatttccga aatcgccttt tgcaagaatc ccgtcgaata
    83581 ttagaaattg gatcagtatg cttaaacagt aataaaaaag ttatgacaag atgttgtcac
    83641 aacctttttt gagtaaacgg tgttcaaaaa cttgcatctg cggtaataag ttcaaccaaa
    83701 caaaaaacat gaaaatctgt ttttgtttgg ctgttcttac tacttgatgc agggcagctt
    83761 tttcactacc tctttttaat aaccataaaa tcctattcct tcatatctcc agcccatcgg
    83821 tgttagccaa tctctttcct tagcactcaa ggtatagtga tgggtaccag ttttttcatt
    83881 tggattaaat agtcgataaa ttggcttgga accaccagaa taaaaactta gaccttcata
    83941 acgccaaccg atttttgtta aagagttgat ctcagattgt gccattgtgt aatgatggtc
    84001 tccactgtaa ggattgtata aacggtagac aggttgtccg ctgtttggtg cttgccaagc
    84061 aatcccttca tattcccagc ctacagttgg cagataattt ttttctccgg cattcaatgt
    84121 atataaatgt tctcctgtat gacggttata cagacgatac atcggagaag ttgaagttgg
    84181 tgctgtatca tactgtgtca gattataggt ttcgattaca ttgttcaatg tagaaccata
    84241 attaggcgca gtggcataac gacctgttag ccaagccgta gcatctttgt aagagttcgt
    84301 attgcttttc catgcaccgg aatagtagta aacgcctggc tgaaaagaag tcgtcttcaa
    84361 taccgttacg ttatcttgca atgattcttt gtacgaagga tattttctaa aagcggcatt
    84421 caccgtaatc cattgcccat tcacatattc cgaagtaggc atcgtaacag attggccatt
    84481 atagcttcct ttaatcccaa atagattgta attaggggca gaagccaaag tactgttccc
    84541 ccagccactt tcaacgatgg cttgagcaat catgactgat gcatataagt cattggcact
    84601 tgccaaactt tgtgcagttg aggcaatact atcaatgaac gcttgttgag aattagcaga
    84661 tgagcgagca taaaaagcat agccagtata gttttcgaat tcagacaaat ctgcttgatg
    84721 ggtatgtgtc aatgtttgcc catctgtcaa ttggttcgtg atttcttctg cattctctgg
    84781 attgttctga gcttctgctg atgtactgtc ttcggtttgt gtttgttctg ttgtttcagt
    84841 tgttggttct tcggttgaaa ttgtattttc tgagacagta gctgactgca aagtactttc
    84901 tgtatcgttt tcaattcctg tttctgaaga actcgatgtc tgagttgcga cagtttctgt
    84961 cgattcttca gctagcactg ttgtgttggc aactgctaga tttcctaaaa gaataacgct
    85021 aaataataaa ttctttgctt tcatcttttt tctcctttga attatgaaac ttttcctaaa
    85081 taacagtgta actaaaaaag taaaagcaag tcaatgtcca tatttaaata acatttgttt
    85141 ctttttaata aatttgcttt ttctgcataa aaagacgtaa atgaagaata ttcttctcca
    85201 ttcacgcctt aaattgatgg tcgtttgaat aactatttaa caagtaattc tctctggata
    85261 ttatccgtta tggattatac ttcctgtgtc gtcggacgga taatcatgtt gctgacagac
    85321 atccggtctg gcgtttctat cgcaaatgct acagcagaag ctatatcttc agatgttaat
    85381 ccccattctt tttgcgcttc atgaagttca agagcagcct ttttgtcgct gatggtttga
    85441 tataattcag tttgaacagc tcctggagag atgatcgtag atttgatgtt attttgccgt
    85501 tgctcttgac gtaatccttc catgattgca cggacagcaa attttgttcc gcaataaacg
    85561 gcggaatcag gataaacaac atgtcccgcc acagaatcag ttgaaatgat atgcccagat
    85621 ttttgttttt ccatgattgg aagtacggcg gaaattccat ttaacacacc catgatgttg
    85681 atatcaagca tattttgcca ttcatcacgg tgaccttcaa ctaatggagc ggttggcatg
    85741 attcctgcat tattgtacaa tacatcgatt cgaccgaact tttccatcgc taaatcgata
    85801 actgcttgga cttgtgcaaa atctcttaca tctgctgttt gaatatatag ctcagcttct
    85861 ggtaaagatt cttttattgc ttttaggcga tcttctcggc gtgcagctat aactagttta
    85921 gccccttttt ctgctaatag cttcgttgtt gcttcaccga ttccgcttga agcgcccatg
    85981 atgacaatca ctttttctga taaatcattc attctattct cctcctgttt tgaaaaatct
    86041 cttgcttata ctcactatct cttatttcat cttactgttc aaataatccg ttcgacaggt
    86101 ttgacgattt tggcagggat tcctgcaacg atggtattgt ctgggacatc tttcgtaaca
    86161 gttgcattcg ctgcaacaat ggcattctcg ccaatcgtta cgcctggcag aatagttgct
    86221 cctgctccga tccaagcatt tttcttgatg tggattggct ttactgacaa gcctcttcgt
    86281 tcttttggat cggttagatg gttcaccgtg atgaggttga cacgaggacc aatcaatact
    86341 gaatcttcta aacagatgcc acctaagtca acgaacatca cttgacgatt gataaagaca
    86401 tttttcccta tactaatatg tttgccgaaa tctgtataaa aaggcagcag aacagtcacc
    86461 gtatcatcta ctttgtcact aatgatattt tctagccgtt tgcggatatc tgctggttca
    86521 tggtacccag tattcagcgc tgctaaaggc tcttcgtttt ccgcttggat ctgatggatc
    86581 acttcaaaga gcggatccgt tactcgaatc tctttattga cgatttgttt ttcgatgagg
    86641 cttgtcattt tgctccctcc ttttatcctt actttataac ggacggctta tgatgtctaa
    86701 tacttataaa acatacttaa ctattccttt taactatact tagtggtatg cttttttaaa
    86761 aacaggaggg aaaaaatgga tattcgtata ctgacgtatt ttttagcagt agctagagaa
    86821 aaaaatatca gccgagcagc aaaatctctg catatcacgc aacctactct ctcaaaacaa
    86881 ctgaaagatt tagaagaaga acttggtgtg acacttttca ctcgaggctc ccgagagata
    86941 cagttgacgg attctggtcg atatctttat tcaaaaggaa aagaaatctt gtcgttggta
    87001 gaaaaaacgg cgaacaattt aacaaatgac gcaatcatct ctggagaaat ctacattggc
    87061 ggaggcgaaa ctaaagcaat ctctttcatt tctgatagcc ttcattcgtt gatcaaggcg
    87121 catcctgata tccagtttca tttatatagc gggaatgcag atgatatcat agacaaactg
    87181 gatagcggat tacttgattt tggactcgta atcgaaccga caaacaaaca aaaataccag
    87241 tcatttcgac tgccagccca agatcgttgg ggacttttga tacatcggaa tcatccttta
    87301 gcaaagcaaa cagtcatcca tccgcaggaa ctgaaaactg ttcctttgat catttcccgg
    87361 caaacgtcag tggacagtca actagctgaa tggctaggtt tcagcataga tcagttatcg
    87421 atcgtcggaa catataactt attgtacaat gcttctttga tggtcgataa cgggactttt
    87481 ggtgcattag ctctagatgg gatcatcaat acttatggga cggaaaaagt attcatccca
    87541 ctcgatccgc cattacaagc ttcactgaat ctcatttgga aaaaagacca gcctctttct
    87601 cctgctgctc gtaaattttt agatgtccta acggagaaat acagttaagt agagtttttt
    87661 tccttcgctt tcagcttttt aacaacgaat aagttaagca aaagatccaa tgattaaata
    87721 acataagttt cttaatttgt tccttccttt tatttctgat aattccagta aattactata
    87781 attataaaaa aagaattgac aaaacataac tgtctatata aaattgatta cgttaacaat
    87841 aattcgtttc atgtgactag atcatactag gcatgaaaaa tctctgagga acatggtttc
    87901 cctaggaggt ttttcgtgtc tatttttgtt tggccgcaat caactggtct agcaaacgtg
    87961 aaaaccaaat cttcaaaaag ggtgcgcgca tgaaaatcaa aaagatcttt aatcaaaatg
    88021 cagtattggt agatgacggt ggacaggaaa aagtagctat tggaaaaggg attggatttg
    88081 acagaaaaag aaatgatttg atttttgatc gtgatgtcga acggatattt gtcatggaac
    88141 cagaaggtca aatcaagttg caaaatttac ttaatcagat tgatgaacgc tttttatttg
    88201 cagcagaaac gatcattgat catgcggaaa ctgttttgat ggaaaagttg aatgaacatg
    88261 tattgatcgc tttgaccgac cacattgctt tttctgcgga gaacattaat aacggtatcg
    88321 tcatccgcaa caaactttta agagaaatcg aagtgcttta cagtgatgaa ttcagtattg
    88381 ctcaatgggc agtagagtat ctgacaaaag agcttgggat tccatatact tatgacgaag
    88441 caggatatat cgcaatccat attcacagcg gacgaagcgg tcggaacaat aaccatcgca
    88501 gtatccgtga agtgacgatt gtatctgaca tcatccattt agtggaatca gaattggaaa
    88561 cagatatcca ttcagaacca ttttcactga attattcaag actggtgaat catttacgac
    88621 tgcttctaca acgaacccat gcgcaacaat atgctgtttt agacacggaa atcgtagaaa
    88681 tggtcaaacg aaaataccca gaaagctata agatttctaa aaaaatccgt gtgttgctga
    88741 ccaaagaata ccagctcgcg atcacgaaag aagaactggg ttacttggcc atccatatcg
    88801 agcgtttaag aagcgcaatc gtacaaacaa atgttaacaa tcatgaggag gaaaaaaatt
    88861 gaaagcatat ctacaacgaa tgggacgttc ccttcaactt ccagttgcgg tcttacctgc
    88921 tgctgcttta ctagtaggga tcggaaactg gtgggcatct tatagtaacg acattgtcgc
    88981 tcatttttta caagctggcg gtaacgcagt tttaggtcaa ttacctttgc tgtttgccgt
    89041 tgggttagca ctagggatgt cagtggacaa atcaggtgct gctgccttgg caggtttggt
    89101 cgcatttgaa gttccagtaa atgttttaaa aactgattca gtagctactt tattgaatat
    89161 caaaccagaa tcagttgatc catcttttgc tcagatcagt aacgtattta ttggtattat
    89221 tgccggattg attgcggcag ctctttataa tcgtttccac gaagcaaaat taccgatggc
    89281 tttatctttc tttagcggca agcgtctagt gccaatcttg gctgcctttg tcatgttgct
    89341 gatcagtgca gtgctactgc tcgtatggcc tccggtttac tctgctttag tttcttttgc
    89401 taaattcatt ttgagtttag gctggggtgg tgcaggtctt tatggcttct tcaaccgttt
    89461 actgatccct acaggattgc atcaagcaat gaactccgtg ttctggtttg acgtagcagg
    89521 aatcaatgat attggtaaat ttttggcttc tgaaggaaca aaaggcgtaa caggaatgta
    89581 tcaagctgga tttttcccaa tcatgatgtt cgggcttcca gcaggagcat atgctattta
    89641 cagaaatgca cgtccagaaa acaaagcaaa aacagcttcc ttgatgttag cagcagcttt
    89701 tgcttcattc tttactggtg taacagaacc acttgaattc tcatttatgt tcgttgcttg
    89761 gccattatat gtcttgcatg caattttcac tgggatttct ttagcagtga gtgcattctt
    89821 ccattggaca gcaggatttg cctttagtgc cggatttgtc gattacttcc tatctttgaa
    89881 aaatccgatt gcgaatcagc cattgatgtt gatcgtccaa ggattagtaa cagcagtgat
    89941 ttactacttt ggctttaact ttgctatcaa aaaattccat ctgatgactc ctggccgcga
    90001 ggaagcagat ctttcagatg acgatactgc aacgactaat tcagacaata aatatgcggc
    90061 acaagcaagc aaaatctacg ctgcattagg cggagccgac aatgtaactt cgatcgataa
    90121 ctgtactaca cgccttcgtt tgcaagtcaa agatacaggc ctgatcgatc aaaataaaat
    90181 caaagccact ggcgtacctg gtatgaagat catcgacgga aaaaatgcgc aagtcatcgt
    90241 aggtacagaa gtacaattcg ttgcagatga gatggcaaaa ctacatggtg gtgctgcaac
    90301 acgacctgca caaacaaaca ccgtggttaa aacagaaaca tttgccggtg gaacgatcga
    90361 acaagatatt tacgctatcg caaatgggaa actgattcca atcactgaag tttcagatga
    90421 tgtattcgcg gaaaaaatga tgggtgacgg ctatgctgta ttaccagaaa atggagaaat
    90481 cttctctcca atcgctggta cgatcacaaa cattttccca acgaaacatg ctgtcggaat
    90541 ccaaacagat gctggtatcg aagtcttgct tcatatgggc atcaacactg ttgacttaaa
    90601 aggcgaacca ttcactttat atgtaaaaga aggtcaaaaa gtcgcaagag gtcaattgat
    90661 tgctttagtt gatcttgccg ctattcaatc tgcaggcaaa aacacggata tggtcgttgt
    90721 attcacaaat ggcgacaaag tccaaagctt agaaatcgaa cccgcacgtg atgtaaaagc
    90781 aaatgataaa atcggctctg tttccaacaa agcctgagcc atcgtcttcc ccagactttt
    90841 ttatcgataa acaaacagga gctgagacaa aaatcttgtc tcagctcctt tttccgaata
    90901 aaaacggcgt tctcctgcca actccgcggt aataagtcca gccaaacgta acatatgaag
    90961 agctattttt tatttgactc ttcttattac ttgatgcaga acagcttttt tacaacctct
    91021 gataaacggt gttcaaaaac cagtttatcg gtatgaagtc aaatttatgc aaaaatgtgg
    91081 aaagccattt tcacaaaatt tttcttcata ctcaaaacta atcggctttt tcacaacctc
    91141 tttatacatt attcctgatc caatatttct tttaatgctg cttcaagaga agttaatggt
    91201 tttcccaata ctttttctaa atcatcagag gaaatagcta actgatcctt tttaatatca
    91261 tgttggatcg ctaaaaacat gtcagctgct tcttgaggga atccggcttc ttttagattt
    91321 tcgacaaacg ctgcatcact tgcttcaata atttctaact ttttacctgt cgcacgctct
    91381 aatgccttgg ctaattcttc atagtcagtt agattgccgg ataattctaa gatttctgga
    91441 gagtcacttt ctactagtac ttttgctgca gcttctgcat attcacgttt caatgcccaa
    91501 cctgtttttc catttcctgc agcataaacg aattgaccag tttttaaagc ctgcccaatg
    91561 ataggtaatt cattctctac ataccaatta ttccgtaaaa atgtatggga aatacctgaa
    91621 tccttaatca ttttttcagt gaattggtga tctggcgcta atacactgat cgagtgatcg
    91681 gcatctgcaa aacttgtata agcgatataa gataccccag ctgcttgtgc tgccttcact
    91741 acattcttat gttcggcttg acgatttcct ggaacgccag agacaaaaag caatcgatct
    91801 attcctttca acgcttcttt cattgagtct aaatcatcat aatcaccaat acgtatatta
    91861 aatccagctt ctttcagtgc ttctcctttt tcttcactac gtactagtac atagatttca
    91921 ttttgtggaa ccatcttttt taagaattcc agcgcataac caccaaaacc tccagttgct
    91981 cctgttacta aataatgcat atttgccact ccctattctt tttatttgtt aagatttaca
    92041 gctgtacatt tataaattac acctttatca taaagagtgt ggtaagataa gtcaagcaaa
    92101 aaaaatgaaa ggatgacaac tgatgaagta ttctctgcaa tttagtgatg caatccatgt
    92161 acttgcctat attgaaatgt ttcaagatac ccgatcactt tctagtgaga tgattgccag
    92221 tagtatcgaa acaaatgcag caaatgtacg taaaatcatg agtcagctca aaaaatccgg
    92281 tttgatcttt acaaaaaccg gaaaaccgca gccttccctt gccaaaagtc cagatcagat
    92341 ttctttacta gatgtctatc gcagcatcga aggtaataca cagcttatcc aagtcgatcc
    92401 aaaaacaaat ccaaattgcg tcgttggtgc gaatatccaa gaagctttag aagaaagcta
    92461 cgctcggctg cagaaaaagg cagaagaaga aatggctaag atcacacttg atagtctgat
    92521 acataaaata gccgttttgg aaaaagaaaa aagaccagaa aacacaggcc tcgtagagag
    92581 atttttataa ttctctctac tgtgcctgca tttttctgat cggaatcgtc tacataaatt
    92641 cttttattct ccgggggaca aaagccttgt catgcccctt tttcctctct aatgctcagg
    92701 tcaaagcgct gaagtcatga cgtcttgata aacggtgttc aagtagctga ccctcggcat
    92761 tagttctgaa aaatgcaaaa tatggaaagc tatttcccat ttttcctctc taatgctcag
    92821 gtcaaagcgc tactttcacg acctctatat tatcatggtt tattgactac cggtatccag
    92881 atttctccca tatatttccc gttggtaact cccatttcga ctacagcatt tggaccccca
    92941 acataggcgt aatcttctac ttctcttaaa acatgcccaa aggccgtatt cgtcaaatca
    93001 tttcttaatt cttcaggcga ttctgctaaa gcgattacaa caagatacgt tccttttggg
    93061 aatgggatga ttcgggtagt gtttggaaca tcctgactcg tttgaacacc gacatagtac
    93121 atcattttcc cgttataggg ttcgttgact gtaaagaaat aatgattttc agcagcttgt
    93181 ttcaatgcat ctattgttcc attaccgata actttttgct caaatgcttg tttctctgca
    93241 gccaaaccga caaaatccgt attgctactc ttcaattcca caccaatacc cgtcaccgta
    93301 aaatctggtt tttcttcgat cctatacttt gccatttctc ccaccctttc tattatatta
    93361 agttcatctt acataaaatt aaagggaaat gacacgatta cgctcttttt tctagggata
    93421 tttttatttt ttaactattt ttttgctttc actgcaatcc aaatctcact gtaaacatta
    93481 ctgaaatcct ctccccattt tgtaaaagag atctcgggag cttcgactaa ctcataatct
    93541 gaagaaggaa gccattctgc atagattttc ccccaagtat cttgtaaagt ttggggaaat
    93601 ggccctttat taggaaaaat ggcccaagtg tgttcttcta tagcaagcat ttctaaatca
    93661 gcgtacggat tttcttttgt cgtagcaaag ccaatcatgt gcatcaaact gcccttttct
    93721 tccaagcggg ctccatcaaa tccataagaa acgttgatta cttgatttgg atataaatct
    93781 cctaacttat gcatctcttc cctttgagtc tccgtgatcg tctgcgctaa cttttgtatt
    93841 tcttgattga ctccttcaaa tttgacagga acttttttcg ccacacctgc cacataaaac
    93901 tgttctttct tttcgatacg aaattccatc gattttcctc ctctgacatc aataaaaaat
    93961 gtcaagcgtg gaaaagattt ttgtatgccg tatctgctga tttctgaagg cagatatcct
    94021 gaccaatcac gaaaagctct tgaaaaacct tcgactgttt catatccata tctaaacgcc
    94081 gtttctgtca ctcttgatcc atctaggaga tcgcgattag ccaaagccaa tctacggttt
    94141 ttgatatagt ccattagcga catccctgca ataaacgtaa agatgcgttt taattgatat
    94201 tcagagattc ctgtattttc ggctattatt ttataggaaa gtccttctgt caaatgttct
    94261 tcgatgtaat cgatcaattg gttcagatct ttaagcatat ttatcttcct ccttgcttgc
    94321 ctttttatca tattatcaaa gaaagtcaat tacttgatga atcaggaacc aatttagtca
    94381 gatgtagaaa atgttgtatg gatctaaaga aaattctcaa gcagcgtttc gtaacggata
    94441 attggtatta tctgcctatc tatgttttac ctttagaaaa ataaattttg gggaagacac
    94501 attctaagta aacaaagcgg taaaaatatc ttttattccc ttagttaatc cgcttactac
    94561 ctactgtaca aagcaaattg ttgttcaaac tgctgatcag aacgctgctt ggatttttct
    94621 ttgcgataca tcatacctct tttatcaatt ggaacaatta tttatttcta acaaaatcac
    94681 ttcatttttg tcagataaat aaaaaacaaa aaaagttcca tctttaaaac acgctattct
    94741 tttacttttt ctcacattct ctaagaaaag aaaaggagaa tgaatttttg acaattcgag
    94801 caaaagtgat tatcaaatat gtaaaatcag ctactttttt cttaaacgtt tctttatact
    94861 aaatataaat aagtgtttca tgaaaggaga actagatgaa taattggctt gagtattttc
    94921 ctgaaaacgt tttggaacgc ggttacagct atcatctgca cggttttgtc cgtcatttga
    94981 actatacaag caagtacttg tccgcaacag tttctggcac ggaagattat aaggtagtga
    95041 tcacttggga tgaaaagacc aacatgactt gtgattgtct atatgccata gaaggaaaaa
    95101 aatgcaaaca catggctgct gtcttattcg cttacgaaga acgtccaata aaaaaatcca
    95161 actactcact ttccgaactc tcgtcccttg tttcctccgc tagttcctct cttgtacggg
    95221 agcttttaac agagattctt atagaacatc cgcaatttat cgaacgcttc aaagttaaga
    95281 tgccatttca tgcaataaat tattcagata aattaacaac tatcatccat aaatacgatc
    95341 atattatcaa gaaaaacaaa aacaggaaaa cagcgaagtt catcatggag atgcgaaagt
    95401 tcatccaaga agcagttgaa tcgctcattc agcaaaatgc ctatcttccc gcattcgaat
    95461 tgatcaatga agtgattgct actctcgaaa cattctattg ggagcctgag gatgaacgaa
    95521 cccttcttct gatagaggac tgttattatt tatggaaaga attattagca gaagcacctc
    95581 atgcagaaaa aaggcaaatg ttctcttggt tcgtctgcca agtcgatcat actgacgcct
    95641 cttattcaaa acgctactcc ataaaaatcc tgaaagaaga ctttcgggaa aaagaatttt
    95701 ctaaccaaaa gaaaaaaata gataaaaaaa ctaaagaaac ggtaaagaaa gacgatttca
    95761 atgaaaaata gcaagtaaac gataacaacc atcctaaatc cacaagaaat acagcagacc
    95821 ttgctttaaa aacacgaatc atgcaaagga tgaagtaaag aagacttaac gcgtacccaa
    95881 tattagtcat ttgactatta ggtacgcgtt ttgttttata agtcatgaca aatttccttc
    95941 gttgctgggt agattttccg gcattgttga tagattttat gatacttttc tacattttgt
    96001 aagagaggtt ccactgcatc tgtatattgg ataaaattct gacaacaact ttcaggtgtg
    96061 tcgaaccact ctaatcttta aagataaata ttaaaataac gattaataat attaacagtc
    96121 tttatttttc accaccaaaa acctatcttt gcatatacta aatagacgta tatacacaga
    96181 taggtttgtc ttgtgaaaaa taatgattat ccttaccaaa aaatgtttgt ttttctacat
    96241 gttcgtactt atcaaaaaat atgatcctta ttgaaattac tggctattta tattccaacg
    96301 acttcttgtg ttaatttttg ttatctcata gtaaattatg tttcattttc acttaattta
    96361 gttgtcacgt gttcgtcaat tcgtaaaaac ggtaaatata taaacacact tgcggctata
    96421 attaatattt gtaaaacagc tgctcgccag tctccggctg ttgctaaaaa tcccgatata
    96481 actggtggcg tagtccaagg aatttgcact actacatgat taattaatcc cacagcagtt
    96541 gcaaaatatg ctactgtcaa agaaaaaatc ggtgcaagca caaagggaat aatcagactg
    96601 atattaaata caataggcaa tccaaaaata ataggttcgc ttatattgaa tatagcggga
    96661 gttaccgata atttagcaaa gtccttataa tcttttctac gactgaagat aaatattgca
    96721 atcaataaag caatcgtatt tcccgatcca cccattaccg caaaggtatc tttaaaggcc
    96781 atattgataa tatgtggaat ttgctctttg tttgcataag ctgccatatt ttcttgcata
    96841 ttctgaatca aaaacggatc taacaatgaa cctgatatta ctgcttgatg gataccaaat
    96901 ccaaaaaata gattagcaat agatgtaatt aacaaaaatc ctggtaaacc agttgtaatt
    96961 ttacttaatg gctctgtaac tatcgtggta attagcttat ttatatccat attaaacaat
    97021 tgaatgatta taaatgacaa taaagcaaac gaggtaatcg taataatgat tgggattaat
    97081 acattaaaag actttaaaac agcgggagga atatttccgg atagctgaat ctgtagtttc
    97141 ttattattag aaagtttaat aaataattct gtagccgcta atccaacaaa tatacctaca
    97201 aacattcctg aagctcctgt ataggatata ggtatcacac ccgtcacttc aacagcttta
    97261 tccgcatttt caggagtaaa catcatctgc ataggtgtta atacaacaaa tgtcgaaata
    97321 gcaactaata ccgctgcaat atgatttgta taatttctgc ttgcacacat atgataagat
    97381 actgctgcta caactaataa tgtagttatg cttaatgtac cattggcaat tgaagtacca
    97441 atttgttgta acgtggtcaa tgtactagta tcgacaattt cccccatgaa tcctgttggt
    97501 tctaagatca ctgaattaat aagtgtcaca aatcctgcta acatcataaa tggcataaat
    97561 gtagcaaacg catctcgcaa agttcttaaa tggatctgat tccccaactt agtcgcaact
    97621 ataccaaatt tttcaaatac aatgtccttc ctgctacttt tgcccatatt ttttctcctt
    97681 tatgcttatt gtaatcgatt actttttcca cccaaataat acatcactta tcaaaaaaag
    97741 taaatacttt taattaaata tatatatctt ttttagtata aaaaaataag ctctgaaaaa
    97801 ataattttcc cgagcttatt tttcaacaaa aacagcttca aaaacaaagt cttgatataa
    97861 atgtctcgat accgaatact cgaaaggttt accagacgat agagcaacaa ctttgtctat
    97921 ctcaatcata aattcacctg gatctatttt taatattttt gcgtcaaatt cattcgcagt
    97981 atctcctttg atacgtatgt gcgaagtctt tatttccaga cccagttcat ttgtgatata
    98041 agcatataca gatttcttta aatgttttgg ttccaagcct ggtatgactg ctaatggcat
    98101 gaatgtttgc tcaatcgagt atggttgaca atcaataaaa cggcttcgta caatattata
    98161 tacatagtct tttacactga tacttaattt atcagctact tttttcgatg gaagttcaat
    98221 tgagaaagta tggatttctg aatctacgtg ttcttcacca accacgctaa acaaaccttc
    98281 gtttggacca agaactcgtg agttatcaat tggtgttctg acgacttcag tcccataccc
    98341 acttctactt cgcaaaactc cttcggaaac aagtaagtct acgcctttct ttactgttaa
    98401 cttgcttgta tgataaataa ctgccaattc atctcctgta ggaagtttct caccaatttt
    98461 atactctcca tttacaattt ttttctttat atctaagtaa atttccatat acttcgcaat
    98521 ttttttcaat ggtgaccctc caatcaaaaa catatcttca tctatacttt aacataaata
    98581 aaccgataaa atccacatca aaattataca cacaataaaa aagatatata tatttaaaca
    98641 aaactattta ctttaagttg taagcggtgt tatcattaag tggaaacagg aggtaaaaaa
    98701 attatgacaa ctatgaaaaa gctaactttt ccagatgatt tttggtgggg ttccgcttgg
    98761 tcagctgagc aagcagaagg aaaaggagaa acaggaaaag cagagactat ctgggatcgc
    98821 tggtttaaag aacaacctta ccggttttat caacgaatcg attcctctat tacaaccgat
    98881 cacatccatc aatataaaga agatatagaa ctaatgaaaa aaactgggca taactccttt
    98941 cgcgtttcta tttcttgggc acgaatgttt ccaaatggcg gtaccggaaa agtaaatccc
    99001 aaagccattt ctttctatcg aaaattattt tccgaaatga ataataacgg aatcaaagta
    99061 tttgccaact tatatcattt tgacatgcct gctactcttc aagataaagg aggatgggaa
    99121 tcacgtgaag tagttgatgc ttatgttcat tacgctgaaa cttgttttaa agaatttggt
    99181 gacttagttt gtcattggtt taccttcaat gaaccacttg ggcctatttt aggtacttat
    99241 cttgaagatt ttcattatcc aaacctcatt gactttaaac gcggagcgca agcagcattc
    99301 ttcactatac ttgcacacgc aaaagcaata caagtattta aagaactagc tcttcctagt
    99361 aaaataggcg ttattctaaa tttgagtcct acttttcctc gtagtcaaaa tcctgctgat
    99421 gtgaaagcag cagaaatcgc tgatttattt tatacgcgga gctttttaga tcctatggtt
    99481 aaagggaatt tttctaaaaa gcttatcctg ttattacaag aatataatca gcttcctgaa
    99541 gattatacga aagaagatct tgtatgtatc tacgaaaata ccgctcaaat tcttggacta
    99601 aactattacg agccacgtcg cgtcaaatct cgttcttcta tggtggatac atctagtcca
    99661 tttttaccag agtggttttt cgaaccacat atcatgcctg gacgacgaat gaacgaatac
    99721 cggggatggg aaatttacga aaaaggaatt tatgatttgt gcatggatat caagaaccat
    99781 tatggaaaca tcgaagcatt tatctcggag aacggaatgg gcgttgcgga tgaagaacgt
    99841 ttcatggatg atacagggca aataattgat gattatcgga ttgagtatat caaagatcat
    99901 cttgcttact tatggaaggc aataaatgaa ggatgtaaca ttaaggggta tcatctttgg
    99961 acatttattg attgctggtc atggatcaac gcctataaaa accgatatgg gctggtttca
   100021 ctcgacctta ctactcaaaa aagaacaatt aaaaaaagtg gcgaatttta caagcaatta
   100081 agtgatacaa atggatttag atacgatgta gacttgttag ttgaataata ttctaaaatt
   100141 ccacttgaag tgaacacatt agaaaacaag aataatgaga aataccaata acaaatactt
   100201 tttcttcata cttcatttat acttgtcagt ataagagact gtgacaaatg tagtgatcct
   100261 cagaagttag gtctggaaat ctaacttgag aagatttttt taaactacgt ccagtctttt
   100321 ttatttgttt aaaattgaag ttgacaagtc ttcattaaaa atttagaata ttcacaagtt
   100381 tgacgacaat tatgaaaatt tatgtcgtgc taaaggagtt ttgttattgg atgaaaagtt
   100441 agatataaaa actgcgatca aagacacgtt acctaccgtt tttggttata tcggtattgg
   100501 acttgcattt ggtatcgttg ggaaagctgc cgggtttcat ccgctggtcg tcacgttgat
   100561 gtccctgctg atctatgctg gttctgccca atttatcacg gtcagcatgc ttgctagcca
   100621 tagtccactg ctctccatcg ttctctcgac ctttctagtc aattcccgaa tgattctgat
   100681 gagtatgacg attgctcctt atttcaagaa aaatcggctg cttcaaaatc tgctgattgg
   100741 cacattgctg acagatgaaa gtttcgcact gggaatgaat aaattgaact atactggaca
   100801 aaagttaaac tttcgttgga tgaatacagc taattggatt tcttatttga cgtgggtggg
   100861 ttcttctctt gttggcgcac ttttagggaa ttttattact gatccgaaaa agtttggttt
   100921 ggatttcgcc atcgtcgcta tgtttatcgg gttactttat cttcaagtca tttctgatag
   100981 aaacacctct aaacgattac agttgatcct gattggtctc actttgattc tggtatatgt
   101041 cggactgatt tttatcccaa gtaacttagt gattttagtt gtaacactga ttgggtgcgg
   101101 attgggggtg tggatcaaac atgccttctt ttgagtttac attgctgact attttaggtt
   101161 gtactttagc aacttggctt tctaggatcc taccatttgt cttactgaaa aaattcgatt
   101221 tgccgcaacc gttgcttgag tatttaagtt ttgtcccgat cgtcattatg tctgctttat
   101281 ggttcagcag tctatttacc caaaatatcg gacatctgcc gcagatcaat ctcgaaaatg
   101341 ctttggcttc agttcctaca cttttagctg ctattctttc aaaaagctta ttggtgatcg
   101401 tcttggtagg aattctttcc ctttcgttga ttcgcttatt ataaataaaa aaacaagagc
   101461 ttatggcaaa ttactgtcat gcgctcttgt ttttatcaaa gtcaaataag aaaaaaatcg
   101521 gcgtattctt gcttatccgt tgaacggacc actaacaacg acttttccta atatatgtcc
   101581 tgtttctacg tctttggttg cttgtttcaa gttcttcgca ttcatcccat ctgaatagac
   101641 cttgctcaat gtactgcgga taatcccttc atttgctaaa gcagcaatgt gcgctaaagc
   101701 ttctccttgc gtttcgattt catagttata gtctgtttta gcgaacatat actcccagtc
   101761 gaagctgata gattggtttt tccaaacacc tatatctaac ggctctttga tccctacgat
   101821 cgttcccaca tgtccaaatg gtcggacaag gtgtttgatt tgatcaaagt agcgggtaat
   101881 atcgaataat acagcgacat actctacttg atcgattcct aattcacgaa aacttttact
   101941 taagtcgtga tgataatcga ttggatagtc tacacctgtt tttttcagcc attcaaaatt
   102001 cttcggactt gcagtcgcgt agacttctag gccagcccaa tgcgctagtt gattcaaaat
   102061 cgaaccgacg cccccagctc cgttgatcac taagattttt ttcccgcggt tggcattttc
   102121 ttctggagtc agaccaaatt tttcaaataa caattcataa gcggtcaatg aggtcaacgg
   102181 caaggctgcg gcttcttcat ctgaaagatt ttttggtgca agagcgacaa tacgttcgtc
   102241 aaccagttgg tattcttgat tgcttcctgc tcttgtcgtt gtacctgcgt aaaaaacgcg
   102301 atcgccgaca gaaaattttt gcacttcatc acctacagca acaactttcc cgactccatc
   102361 aaaccctaag atacgtaaag catttcttat cccgttatct tggcgaagtt tcgtatcgac
   102421 aggattaaca gatactgcgt tgacttttac cagaagatcc cgtgaactgg gtacaggtat
   102481 ctgttctttt tcatcaataa agctttttgg atcatcgatc gacaaccctt cataaaaacc
   102541 gactaccttc attaattcct tttctgacat acgaattcct ccttagcttc atcaagttgg
   102601 agcatccata cagttttcat ttcaatatat atagtatgct atttgttcca cttttattca
   102661 tcataattat tctcttactt aaagtaaact atttgcactt ttttggttaa aaaagaggtt
   102721 gcgacaagac ttttgtcaca acctctttta aacggtgttc aatcaactga ccctcggtat
   102781 tcgctcaaaa aacgacaaaa tatgaggagc tatttttgtt tggctgttct tattacttga
   102841 tgcaggacag ctttttcacg acctctaatt cacggtgttc aagcaagaaa tcattgttca
   102901 ctgaaaagcg ttggatgttc tttttcaaag gtgtctaaga tctctcgtac ttcatcagta
   102961 gatttcgtat tcatcaactg aactcgcaag tcatttgctc ctggaaatcc tttgatatag
   103021 attttaaaga aacgatgtag tcctgtgatg gaacgcggga tgatttctga ataatgatct
   103081 tgcagatcta gttgcagacg aagtagtccg atcagttctt tttctgtatg ttccctcggt
   103141 tctttttcaa atgcataagg attcttgaaa atcccccggc caatcatgat gccatctacg
   103201 ccatattttt cggccaattc ttctcctgtc tggcgatctg ggatatctcc gttgatcgtg
   103261 atcagtgttt gcggagcgat ttggtcacgt aaagcaatga ttttagggat gacttcccaa
   103321 tgtgcatcta ctttactcat ctctttacgc gtacgcaaat ggacagaaag attggctata
   103381 tcttgatgaa gtaggtgact gatccattct tccatctcag acatttccgt atagccgata
   103441 cgcgtcttga cgctgacagg caaaccgcca gctttagccg cttcaatcaa ttgtgccgct
   103501 acttctgggc gaaggatcaa gccactgcct tttccacgtt ctgctacatt agggactggg
   103561 cagcccatgt tgatatcgat tccttggaag cccatttctg ccatagcaat gctcatttct
   103621 ctaaaaaatt ctggcttgtc tccccaaata tgggcaacca tcggctgttc atcttctgta
   103681 aaggtcaatc ttcctcgtac actgtctttt ccatctggat gacagaaact gtctgagttt
   103741 gtaaactcag taaagaagac atccggtgct gctgcatgct ttacgacatg gcgaaataca
   103801 acatctgtta catcttccat tggtgctaaa acaaaaaaag gctttggcag ctctttccaa
   103861 aaattagtag tcatttattt gttactctcc attctatcaa gcagtgaagt cgcaatcttt
   103921 ctcaaaaaca ttgtcattat actaggaaac aaaaaaagaa gcaaagtgaa cagcttaaaa
   103981 gatgtttctg attgagcaaa aaaagactgt gacaaaaatc ttatcacaat tccttttccg
   104041 gaataaatgg tgttcaaaag cttgcatctg cggtaataag tccaaccaaa cgaaaaatag
   104101 gaggagctat ttttgtttgg ctgttcttat tacttgatgc agaacagctt tttcacaacc
   104161 tctccactaa acggtgttca atcagctgac cctcggtatt agctcaacaa acgacaaaat
   104221 atgaggaact attttcccgt ttgtttctct aatactcagg tcaaaacgct gatttcacaa
   104281 cctcttttct aacttctcaa tcctcttcct ttattgatca aataccaagt aacggcgtac
   104341 aaaacaacga tgaatagcac aagtacgatc atcgatgttg ctactggcac atcgattgtt
   104401 ccaaggaatc cgtaacggaa accgaagatc atataaacga tcggattgac tttcgaaaca
   104461 gcttgccaaa atggcggcaa catagagatg gcatagaaaa cgccacctag ataagttaac
   104521 ggctgcaaga caaatgtagg cacgatcgat acatcgtcat aagactgagc aaaaatcccg
   104581 ttgagcagtc ctgctaacga aaacaagatt gccgtcatca ataatgtaat gatgaccatg
   104641 aaccatgaat acacatgaag tggtacaaag aacaaggaaa tgatcgttac gagagagccg
   104701 acgagaatac tgcgacccac tccgccaatc acaaagcccc aaatgatcac atgcgtagga
   104761 acaggcgcta ccaagatttc ttcgatgttt ttctggaatt tttgagagaa gaaggacgaa
   104821 gaaacgttgg catacgaact agtgatagca gacatcataa tcaaaccagg cacgatgaat
   104881 tccatatatg aaaaaccacc catgtcaccg atccgaccac cgatcatttt tccgaaaata
   104941 acaaagtaca aggatgtcgt gatcacaggc ggaaccagtg tttggaccca gatacgcaaa
   105001 tagcggttcg tttccttgat agctaaactt tttaatgcag taaaataaag attaaacatt
   105061 tttctcctcc gtatgattat tttcttctgt gattttcaaa aacagttctt ctaaacgatt
   105121 cgacttattc ctcatagaaa gaactttgat tccttgtctt gtcagctgat cgaagattcc
   105181 gttcacccct tgatttcgtt caacttcgac agcgattgtc tgttcatctt caaatgtaca
   105241 agcgtatcct tcaatcacag gtttggtctc atatggcgct aaatcaaaga taaatgtttc
   105301 aaattgcagt ttggatagaa gctctttcat actagtattc tcgatcagtt cacctgattg
   105361 gatgatcccg atgttgcgac aaagcatttc agcttcttct aaataatgcg tcgtcaaaat
   105421 gatcgttgta ccattttcgt tcaattctcg gagaaactcc cacatctcgc gtctcaattc
   105481 aatatcgact cctgctgttg gttcatccaa gatcagcaaa cgtggttcat gcatcaatgc
   105541 cctagcaatc atcagtcttc gcttcattcc cccggaaagc atacgtgcac ggacatttct
   105601 cttttcccaa agattggact gcttcaaata tttttcgctg cgtttcatcg cttctttgcg
   105661 agagacaccg tagtagcctg cttgattcac gacgatttgc tggaccgttt caaagggatt
   105721 gaaattgaac tcttgcggga ctaatccaat ctgttgcttt gctcggacta gatccgtatc
   105781 cagatcataa ccgaagacat tcacttttcc agatgtttta ttgactaaag aagtaatgat
   105841 tccgatcgtt gtagacttcc cagctccatt tggtcctaat agcgcataga aatctccttc
   105901 tttcacggaa agatcgattc ctcgcaatgc ttcgacccca cttccataaa cctttttcaa
   105961 attatttatt tcaagcgcat ttgccattta tttcctatct ccttatagac atgattcttt
   106021 attgtatcat ggaatacagc agatgaaaaa acaacttggt tccagcgaaa aatcaggttg
   106081 ctgggctcag gaaaatctcc taatgaaaga catcaatcgg acgaagtcag acaacctttt
   106141 cagaaaaaac aaatcgaaga taaaggatta ctattcatat gtgcaacaaa aggagcgtga
   106201 gacaaaagta aagaacactt ttgtctcacg ctctaaacac gtataaacgg cggaagcaaa
   106261 agccaagatt tttgatccaa taaatacttt cgatcacttc gcctatccca atacatgcca
   106321 ctgccgcttt tcatcaaata acgcggcttc cgtttttgcg gtttctacta aagtctctgg
   106381 gtaatccaaa actttcagca aggcaatcgc atttcgggtc cttgaaggtc cttcttttaa
   106441 tttgaaatca aaactgattc cttttccttc tgttacttgt tcttcaaagt ggacattctc
   106501 acaataattc tttaaaatct ctgtcaattc gatatcatgt gtggcgacaa atgctaaaga
   106561 tggatactcc gcaagccacc gaacgactga agcggaagaa gcaatccgtt cgatcgtatt
   106621 tgtccctttt aaaatctcat ctacgaagca gtagcagcgt tctttggaag ccacttggtc
   106681 caacaaacgt ttgatcgatt tgatttctga aacaaaataa ctgtcgcctt caaataaatc
   106741 atcttcgatt gccatggaag tcaacacatg tccaggttgc agggtaaact gttctgcaat
   106801 cgctgtttgg atcgtctgtg ctagaataca gctgatggct atacttttga catacgtaga
   106861 ttttcctgat gcattggaac ccgtgactaa tgtattcttc tgccagttga ccggattcac
   106921 taccgcttct tttaacaatg gatgatagat atctttcgct gtcacaccgc cctcagtaaa
   106981 ctctggtcgg caagtgatgg gcatataagt acggtaattc aatattgcag cggctacttc
   107041 taattctccc agcaattccc acagcttgat ggcttcagtt gaatgctttt ctaatttagt
   107101 gagaacgaaa tgataggaga taaatggcag catgaacatg atgttgacat attcaaaaat
   107161 caactctgct tcactcccac tcttcatacg aaatgaaaaa cctaatttag ggatgtctct
   107221 taatggttta gtttgctgtt tcagctcttc ttgaagtggt gtcggcagtt ttgctagctg
   107281 attggcggct gaaatcgttg aaaccaaata actcatgcta ttcagctctg tttctagtgt
   107341 ttgtttcttc actagataat agaccgtatt gaatactaac ccaccgattg ccaaatagat
   107401 tcctagtact tgtcctaaaa gaagcaaacc caaacccacc agcggaagca agccaagaaa
   107461 aataaataaa cctacgcgtc caatcttttt actttttcca tccgctagat attgttttgc
   107521 aaaattatga tctttttttc ctaaacgagc gaattgatat tggatttttt ctctcagttg
   107581 aggattttcc tgataaaaag caatcagttt ttctaactgc tgatcttcac caaaatcaaa
   107641 gctgcgtaaa cgttgataca acgcttctga acctacacta gaataggtac tgttgattcc
   107701 ttcgaatact tcgaacatat ccaggtcata ccaagtaaga tcatcgattt cgctatccca
   107761 tgaacggaac ttcttctccg tgagccatgc ttccttcaag ctttcttctt tatcaaatct
   107821 cggttgataa ggaatttttt cccatttgct acgaactgtt tcctttaatt tcaaacgtga
   107881 aaaaatgtct aaagcaacta ataaaataac agctgcaata ataattaaaa cgataaattc
   107941 tctttgaccc atatccctct ccgttccttt atttgttagc tttagtatag cactgttgcg
   108001 ctatttgaaa agagggtaaa aaaacacctt tcaaaataaa aggtgttttt ttcttgtata
   108061 ttacatattt atctctcatt tatcaaaatt gacaaataat catagggagg aattgttgtt
   108121 aattcttgtt tattctccag tgcattgaca actgtcccaa gggaaaggat agcctcaggt
   108181 actatttttt cttgttctgt tggattagct aagcgaagaa caaatccttg ttcatgaaaa
   108241 taagaaggat aaatcgatga tacaattaag tcttcaggta attcaatcaa tgaaaattta
   108301 cgaggaacat caagttcatt ttgtaatggc caaatcttgt tatctaacct gtgaataaat
   108361 acattcagtt tctgcttttg ataagaaata gattgttcta accgtttttc tgcctgtttt
   108421 gccactttga actcattaaa tcttccttct tctacattaa atccaaaagt gactttatac
   108481 tcacctatct cttgagctag cggtgtttcc atcatgacat gcccttcatt tgtcgtatct
   108541 cctgaagctc gcccaggtcg ccaagcaaga ttaggttttc caagttcccc tgttgttgaa
   108601 aataaggtta tgattaattg attttctata cgttcatact cttttaaacc atctgcataa
   108661 aacgtaaaat aatgatcatt ttctgccaca gagacactct tatcgaatat ttctaaatta
   108721 acaggtttct ctaccatagt ttctgaccaa ttcggaggaa tgacatcagg ggtattttca
   108781 ataaatccgt tttgaatttg tgcaattgat ttttcagatt tatctaaaac attaattgct
   108841 aagcgcatac gatgcgagta aacagtatta tgaattttga gtgtgccttc aacgatttga
   108901 ctttctccca gactgaacga tatttcataa gatatttctt ccatttcggg tttttcagat
   108961 aaacgatctt ttaaatcttt aggaagttga gcttttccgt aaacaactaa tgtttcttgt
   109021 aaagaatctt tatatacttt agctgtttct aattttagag atagttctgt atctccttct
   109081 aatggtgaat aatcatacgt atcgccatca tttgctgaat cgatcaaatg aacgaaatca
   109141 agatattgtc tatctccaac tatcaaattc aattgcccat ctttaaaaga aagtttatat
   109201 ttattgttac ttatctcagt tttgtctatc tcgattgctg tttctaattt ttcattattt
   109261 ttctcaaatt caacaacagt gtatcctagt gctggcacat ttacatttat ttttatgtca
   109321 agttcataat aagctggttc atcaaaatat tcgaaacctg tagcaatcat ccgataagca
   109381 tttttccgtt ctggaaaata aacttctttt tcaatgatat tatagggact acctttgaag
   109441 tgtattttct ttgaatcagc tactacatgc acgattttcg atccactata attctcagtc
   109501 gttgtgttga aaacaaggac ttcattcgat tttagcttta atgcatcagc catccgtttt
   109561 acaataaggt tttcgattcc gtcagctatc tcattagctt ctttgattcg atggaaaata
   109621 tcttccgcaa cattatctga aacacagcca ccaatactat catgagcctg gttttgcaaa
   109681 atctttttcc ataaccgacg aagtaggcct ttactgatat ggataccatt tctttctgca
   109741 atcagcatga gcggctcaac tcgttttaga attttttgtt ccaatttaaa attttctatt
   109801 ttcatttttg ttcttactga gccaatagaa cgatgaacac gagagtaaac cggctgacga
   109861 agttcacctt tatattcagg taattctttt ttgtttctga taacttctac ataagaagga
   109921 taatctgaaa taatattgtg gaatttactg tatttattca acttctctac gacttgatca
   109981 aaatttaaaa tcattgactt ttgatctaca cccgaaggta ctaaaatatc tttgtttttt
   110041 ccttgcatat gaagcatttc aactgcttca tccaactttt cttttgcaaa ttcaggaata
   110101 tctttaattg cgtctaaggt catcattcca gtcatataac caaatggaaa attcatggca
   110161 taaacaaatt tatctcccaa tcctttccag ataaaataag gagatggaac catcgtttca
   110221 aagtttaatc ctcgccaaca catgaaatta tcgatttcta cttgatgcaa aagtgtaggc
   110281 aaattcgcat tgaacccaaa cgtgtcaggc aaatacccta ccatcattgg atctccatat
   110341 ttaaggatcg tatcactgat tccaatcatt aagtttctta aaattgattc agcatccact
   110401 aataaggcat ctgtttgtgc ataccacggt cccacgaata gttgtcctgt tttcatcagt
   110461 cgttggataa ccttaagctt ttgcggattg atctccaaat actcatcgac gattgaagtt
   110521 tgtccatcta aacaaaagtt tactttaggg ttcctttcca attcatctag aacttcagta
   110581 aagacctgat cagacaatac gatggcatct tcatttgtaa aataccattc tctgtcccag
   110641 tgcgtgtgtt gaattatatg tgcatttacc atatcagatt ctcctacttt ccttcttcta
   110701 ctgaatttac ttgttgttct tttttatact tgatggattt tagtgcattg accattaacg
   110761 ctgtaaccac tcccccaata acaattgata ctaaatataa aggtatattc gtaacaaaag
   110821 gaattgccat aaaggttgaa agcattgttt cttgagtaac accaaaaaat ccatttagac
   110881 cacatgctac tgcagtgccc accacgatgc ttggtattac tcgtaaagga tctttcacgg
   110941 caaacgggat cgtcccttca gtaatcccca caaggcccat aatcatagct gtctttgcat
   111001 tatctcgttc cgattcatca taaagttttt tgtttaaaat tgttgctaaa aacattccaa
   111061 atggcggaat agcaattcct aataacatgg ctgtactagg tccaaagctt ccgcttgaaa
   111121 aagaagcaac cccaaaagca tatgcgattt tattgatagg tcctcccata tcaaacgcca
   111181 tcattcctcc taaaatagcc gacatcaaag cagcatttgc tcctgacatg ccttctagcc
   111241 aattagtcag tcctgttgtc attgcttgaa taggcgtagc tagtacatac cataatatga
   111301 ttccaacaac taatgtagta acaaaaggaa tcagcataat tgattttaga ctaataactt
   111361 gcatcggtac ttttactttt ttcaatgcat tagctaaata gccacaagct aatccagcaa
   111421 ccattcctcc aataaatccc ataccaagat tttgacacat catcccagtg ataaaagctg
   111481 gtgctagacc gggacggtca gcaattgaat atgcgatata ggctgaaatc atcggtacga
   111541 taaactgtaa tcccgtctga ccaatcattc gcaggactcc ccagaatgta tccgtctggt
   111601 cccaaacacc tgtgccacca aaaatgactg caatagaagt tagtaaccct gctgctacga
   111661 caagcgggat catataggaa accccacttt ggaaatgatt tagaatttct cttccttgtt
   111721 tcttgaattc cattagtaac tcccccacga tatatttttt atttgttaat taatgcaatt
   111781 gcttcatcaa tcgtctcttc accatctttt actacctctg aggtccctac tgttaaaatc
   111841 ggtttaccgt caaagcgacc tcgttctgaa acatttgtat ctactgcaaa tatgacaaca
   111901 tctgcctcgg aaacatccga aattgaaagt ttgttttcta tccccatagc cccctgtgtt
   111961 tctactttaa tatctaaccc tttcttcttc gcaaactttt ctaaattagc ttttgccata
   112021 taagtatggg caatccctgc gatacatgct gttactgcta ctatttttgt catatgaaat
   112081 tcctcctttt aaaatgatag agcttttacc aattcttttt tatttctcga atcttttatt
   112141 cttttaacaa actcgtcatc catcaatctt ccagataatt ctgctaaaat acgtaaatga
   112201 ttagtacctt tatcagtgtc ttttattgct aacaaaaaga cgagatcaac tggttgatca
   112261 tctaatgcgc cccattcaac agaccgcttt aacttggcta cagccactgt tgattcaatt
   112321 actgctaggc ttttgccatg aggaatggcg atatttttcc caattcctgt ggtcatatgg
   112381 ttttctctgt caaatacgtc tttttgaaat tgtttgtggt cagacacaaa cccattagtc
   112441 tctaacaatt tcgataattt ttcgactaca ctttttttat cagatgcatt taaatctatc
   112501 actatattat ttatattgat tttttcactg atcatttata agccttcttt caatatataa
   112561 actaattttt caaacgacga actcgttttt aaatttgcta ataactcatg attcgaagcg
   112621 atttcattga atgtttcata aattttattc aattcaggtt ttactttttc attaagtgca
   112681 aaaaagaaaa cagaatgaac aagtgtccca tcccaatcaa ttccttctgg attaacgtag
   112741 acacagatta ctggcttttt tataaaatct acttcgatat gcggcatagc aaaatcattc
   112801 atcgctgttg aagatagttt ttctcttttg attgctccct ctagtatccc ttctttcgcg
   112861 taattttctt ttaccaattt tttggtaatt atatttaaaa cgttcacttg attatccttt
   112921 atttggtggg taaaaaagca aaatcgttta tctaataaat ttagaaaagc atcttctgtt
   112981 tgttcattta actgtagata ctgttttact tttctgacat ctgcccctaa catcaaagga
   113041 ctaacaacaa taacaggaaa atttgtattt tcaatcggaa tcgtgcttat aacaagttca
   113101 tcagtgactt ttctatcttg tagttcattg atgcttagta catcttctat ctcaaccata
   113161 tctgcaaaac cgttatttat tctttgctct aataattttg atgttccata tccgctacta
   113221 caaactaata tcactttcgt tttgtcaggt ttgtaacgat ccaaaagtga ttgaatatgg
   113281 agtgttacgt aagcgatttc atcttcatta aaatgtatac agaatctctc ttcgatttcc
   113341 tctaataaat ctacacttat cataaatgac cttttaaaag aatatttgat tttgtccgta
   113401 taagggttat agatatttac tcccaatttg agtcttttaa ctgctgcatt gagatgtaat
   113461 actagattat tgatcaattc ttcatcagga taaaattcat ttaatttaat tcttactaac
   113521 tcttgtagct caacacccat atctaaatag gaaagcttcg tttgatctaa gtcgtgattc
   113581 atagcatttt tttcaatcga agtaatgtga atgtcaacat aagcttgttc atctattggc
   113641 acaataattg aaaatgcttt ttcaatcatt ttgattaaaa taagtgtatt ctttgagatt
   113701 tcttcttcag aattattact acgtgataag aaattgcttg tttcaatcct ttctatcgca
   113761 atagcaaggt ggatagctaa agtttgaaat tcataatctg taaatttcaa ttgtgtctta
   113821 ttcatgtatc gattaagcaa ttcggctact tttttcaata tgtccttatt taagaaatta
   113881 ttcgcttcac caatgaaatt gatattcaag tctaagagat ctgttttact gttagatgct
   113941 gtaaagccac cccaataata gttcacaact tctgacatca accttctttt acttttttca
   114001 tcagctttga tgcgcacgcc atttcgatct gaaactaagg acatcccatg cttgtttagt
   114061 ctttttctaa catctttcat tgtgctttct accgtcgacc tgctcacgta taattcgtca
   114121 gcaagatttt gaatctttag agaatcatta gtattcaata atttagcaaa cacataagtt
   114181 agacggtcct ccggagagtc tgcgatattg attttatgac tggataataa atttcgaagt
   114241 gtttcttttt ttccaataag cgaaacgcct tttttaggtt gaaccaacat ttgtacatct
   114301 ggcatttttt ggattatttc tttcaaaatt aaaatatctt tgctaattgt tttcgtagat
   114361 acatataatt gttctgataa ttctttgtaa gttgtgtgct cattttcaat caaaaagtat
   114421 agtattttca tttgccgttc gctaaattcg atgcccatta tcttcacctc ctgaatacag
   114481 cttaagtgta caattattat ctctattttc atacagaaga aagttcttga ttaatgtaga
   114541 agtttctaat attcttgatt atttcaaatc aataaaaaag cctgcaatat ttatatcaca
   114601 ggcttttttc tctattaaat atatataaga taatacattt ttctactagt tctcactaat
   114661 cttgtataat taaaccctcc gcaacttgac ggagatggag aagatgcccc cgtctaatct
   114721 agcggtcatc tctcctccca ttccttccac caattttttt gacaggtaaa gcccgattcc
   114781 gctagattcc gtatttgtgc ggctggtatt ttcggtataa aaacgctgga agactttttc
   114841 aacagaggtt tgcgttcctg gtttgatagg attggccact gttaatcgaa tgaatggatc
   114901 ctcttttgaa aatgtcacct ttgcttgtcc atctgcataa cgcaataaat tctgtatgat
   114961 attttgcagc actcgcagca acatgagcgg atctgctaat acagttgtat ttatcgagtg
   115021 ttcagcgaac gctacctcga tatttttctc agaaaattgt tcataaaaag agaaaaatac
   115081 ttcttccacc tctttagaaa aagaaagcgt atggagatcc atttcttttt gcttcgtctc
   115141 tattcgagca agatcataaa actgatccgt catactgagt aatcttgcaa cagattgttt
   115201 gatgatcgtt aaatacttct cccgtttctc cgtatcctct acctgttcca gtaattgtac
   115261 ataaccgtta atagcagtca aaggagttct gagatcatga gaaaggccga cgatcgatag
   115321 tctgatgttt tcttccattt cttgaaatgc ttgtcctttt tgttcatttt catccaacca
   115381 tgtattcagt gcatctacta ggtccattag attcttttct cgaaattcga ctgaaagacg
   115441 accaccatat tcttgtcgtt cagaaagagt ggcgattttc ttagttaatc tcttgatttc
   115501 cctttgcagg aagaaaataa aacttcccat aaagataaca acgagaagca acagccattt
   115561 aatcaaatct aaaccccact ccccacaccg tatgaatata cacagcatgt gcctttgcta
   115621 gcttccctcg aagattggaa atatgcatat tcactgtttt ctcactatca aaatatggtt
   115681 cttgccaaac tgtttcataa agatttgctc gcgaaaatac ttttttcgga tgttctaaaa
   115741 aaagcttcag cagatcgaat tctcttcctg tcaaatggac agccacacca ttcacattta
   115801 catccctcga ctctttgtcc agtaagattt ccttgtaata gatgcgttgc gacagatctt
   115861 ttacttggac agaagtctga tgacgaagtt ggatgccgat tcgtaacaaa agttcttcga
   115921 tatcaaatgg tttcgtcaca tagtcatccg ctcctgctgc caacaaggaa actttatctc
   115981 tttgatcgct ttttgctgaa agaacgatga tcggaacatt cgatgtctgt cggatttctg
   116041 ctaacaatgc ttcacctgaa agccctggaa gcatgagatc tagaaggatc aaatcgacag
   116101 gatatgtgct taacaataat tttccttccg tacctgaata agcatcaaga agtttgtatc
   116161 tctgttcaag aacctcctcc agtaaggaat gaacagcttc atcgtcttcg ataatcaaaa
   116221 tagtttccag caggaccacc tacttaatgt cagatttttg gaaaataaac attcctagag
   116281 ctgatgatac cacgattgtt actagactga ccagaatcat tttcggtgct tgcgaataag
   116341 ttgcttgttg cgcaaagtcc gtatacatga gccacgtttc cgtaaaccac tccgttagaa
   116401 attccaagcc tttgattttt gcgaaaacac cgggaatgaa ggccgttccc atgatataaa
   116461 gaaaagaaag aagcaaactg acactggtac ttctagtgat gaatgtcaaa gccactggaa
   116521 cagataatgt ccctaatgtc agcagaagca atacaggaaa tacttttaga acataatttc
   116581 catagttttt gattccctca acttcaccaa atccgaaagc aagtgtgtaa gcaagcatgg
   116641 ctagtcccgt gatcaaaacc acgccaagtg ttgtgatcaa aagcgtaacg agaagtttcg
   116701 acacataata agtcattcga ttccgtccta aagataacgt attgcgaatc gtaccgtttt
   116761 gaaattcttc cccaatataa aagcacgcaa atgctgcgaa agccagaaga atccatgcag
   116821 ccattttttc taccattaaa atccctgttg caccgttgat gactgtatcc gttgcttggt
   116881 ttaattcatt gccgtatttt gtatgcatat accattcgtt ccaagaataa aaaagcggaa
   116941 gtacgaccat cagtcctagt gagacccaca ttttacggct cttccatact tttatttttt
   117001 cagcagttaa tagattaaac atgtggattg cctccagtta attgtaagaa ataatcttcc
   117061 agtttttgcc caactaggtg aataccatcc acaggaactt ttgcttctac caatgcttga
   117121 ttgatggctg ctacttggtc aattccttca aaaagctgga taacacggct agattgtaca
   117181 aaataatccc tataaccaag agagtcgaga accgttactg cttgttccgt cgccgaagtg
   117241 tcaattttta taaattgacg agattcttgt gccaattctt ctttcgataa ttctttgatc
   117301 aagtgtcctt catgcaaaat accatagtga gtggcgatct gtgacaattc atctagcaag
   117361 tggctagaaa gcaagacggt gatgccccgt tcttttacca aacgttggat gatttctcgc
   117421 atttctgcca tccctgctgg atccatccca ttcgtcggtt catccaaaat caaaaattct
   117481 ggattcgtga tcagtgcatt tgcaatagct aaacgctggc gcatacctaa agagaaattc
   117541 tttgctttct ttttccctgt attttccaat cgcatcattt tcagcaggtc ttcgatttct
   117601 ctatccgaca caccgccgtt cgctgcttgg atacgtaggt tatctcttgc agttaattct
   117661 ggataaagag caggggtttc aatcgattga cccatacgtc gtcttgctgc ctgcaaatcc
   117721 gtcgttccaa ataattcgat cgaaccttca tcaatcgaga tcaaacccat aatagttctc
   117781 ataaaggtag acttacccgc tccattttcc ccaatcaatc catagatcat tccacgtttg
   117841 atttcgattg atactttatc taatgctttg gcagcaccgt attttttggt tataccagtt
   117901 gctttcaaga ccgtttcatt tccaaaatcc atacttatcc ttctttctta ttgatgagtg
   117961 aagtatagtt gacgggtata aagaaagcag ccagaaatgt ataaagaaag tgtaaatttt
   118021 ccaattgaat gtcaaaaaaa acaatcggac aatacgtgtc tttcctatta tcaggcagtt
   118081 tgttatacgc ttgtatcagt ttcctgattc tttcttttcg accaaagtcg tttctctgta
   118141 ttcctcttca ctgaaaattt ttgcttcttt cagatcaagc ttgagtaatt ttaccagacc
   118201 ggttataagg ataactatag caagactccc tcccagaaaa attagactgt ctcgcagacg
   118261 tggttgcgtt gtcttccaat caaagagcgc accaaacagt gctaatccaa gtggactggc
   118321 caccatggta atcgttgtta tcgttgacat aagtcgtcct tgtatatgcg ttggaacttc
   118381 tcgctgaagc cagaccatat aaaaagcaaa agaaaacatt aatccttaaa aacggactta
   118441 tgaaaaataa tacatgccgt ttgggattta caattagcta ccaaataaga ggttatgaca
   118501 aaagactttt cacaatccct tcttccgaat aaacggtgtt ctcctgccaa ctcctcggtc
   118561 acaagtcaca atatttatca aacatgagaa gcaatttttg taaattcctt cttatttctt
   118621 gaagctgacc acttctgtca caacctcaga agcggataaa taatattgtt tgatgatact
   118681 ttatcttttt cccgtttgtt tatagatcga atgatattat agaccaagaa tcctacctat
   118741 taacatagct aaaaacacaa aaaaggcact ttccaaattg tggaaagtgc cagaaaagtt
   118801 aggattaagg taactgcgct cagcattgct tcgcccagta cgattctcgt aactcgtgaa
   118861 ctcgaacgat aatcgcaatt aacgttttga gaactgtgaa gctttacggg ctttcttaag
   118921 acctggtttt ttcttcgtat cattgaataa gtttgaaaaa ccttgattta taaaggtttt
   118981 cccgtaaata tattttatta tatttgatta aatttgaaat gtttgtgttc taaaatgtgt
   119041 tctaatttaa aggcagtata tttcgtattt tagattaaat ttttaggctc attcattctc
   119101 aaatccattc tattcagtca ataaaaattt taaaaagact ttataaacaa agatgttcaa
   119161 gcgagcatct tatttttttg tgcttaattt gaaaggagaa catttcatgt ataaaaaaca
   119221 aaaaaagaaa ttatgtgtat taactatttt gagtttggct gttcaagcaa ttgttggagc
   119281 aattgctcct acgattactt ttgctgatga aattacccat ccacaaacgg taaccgtaga
   119341 actagattta gcacatcaat atgctgttga aggaactttt agtgatggtc gtccaatgtc
   119401 agaagtcact gttccgcatt atgcagtgta caacggcttt aaacaagata ttttctgtat
   119461 tgaaccagga gtcccgattt acaatgagtt cactcctggc tatgagaaaa acccgttacc
   119521 agatatgtcc gataaagcca aattagtttc cgttttatgg aaaaaagtag gtacagatgc
   119581 agatactcat attgtggcac agaagatgat ctggcaagaa gttaatgggt atacccttca
   119641 ctcaataaaa cgatcagatg gtagtgccgt aaatatcgca gccattgagg caaaaataaa
   119701 tcaagccatt gacgattatc agaagaaacc aaccttccat aatagtacgg ctaaaacagt
   119761 attagggcaa tcgactactg tgacggatac gaataatctg aatttgtcag agttcgatga
   119821 ggttgtggaa aatgccgcaa acattgatta tcgtgtgaat ggtaatcagt tgataatcac
   119881 cccaaatgcc aattcaaaag aaagtggtgt gctgacgctt aagaaatctg ctggtaccgg
   119941 aacacctgtc gcctataaaa aggctggcca acagacttta atggccgggg cgattgataa
   120001 acctaatacc tacacaatca aaattgatgt ggaaacggag ggttctttaa agatcaaaaa
   120061 agtcgataaa gaatcgggtg atgttgtacc aggaacggtt ttccatttag actttggaaa
   120121 aactttacct gcaaaagacg tgactactga caaagaaggc attgctacat tggatgagat
   120181 tcctcatggt acaaaagtaa ccattaccga aaaatcagta ccggcgcctt atacgattga
   120241 taccaccccc atgactacca ccattaaagc aggcgaaacc atttacgtga cttcaaaaaa
   120301 cgcacgggaa aaagggcaaa tcattctgga taaaagcgga gttgaaacag ggagtgatct
   120361 ttggaatgac aattattcct tagctggtaa tacgtttgcc attcgcaaag acagtccaac
   120421 cggtgaaatc gttcaagaaa tgaccacgga tgaaaacggt catgcggaaa caccaaaaga
   120481 gattgctaat gcgttggaat tgggaaccta ttatgtgacc gaaactaaag ctagtcatgg
   120541 gttcgtgaat acgttcaaac ctgtaaaagt cgaattgaag tatgccaatc aaaccgtagc
   120601 ccctgttacc agtaacgtaa aagggcaaaa tcaagaagtc actggcgaaa ccactttgac
   120661 gaaagaagac aaagatactg gggataaagc acaaggtaag gcagtctttg agggtgctga
   120721 atacaccttg tttactgcta aggatggaaa agctgttaaa tggagtgagg cttttaaacc
   120781 agagttagcg aagggaacga aaggttctga tgaaacggtc actttgactt tagacgaaaa
   120841 gaaccaagtt gccgttaaac atttagctat caacgagtat tattgccaag aaacaaaagc
   120901 gcccgaagga tatagccttg atgaaacaaa gtatcctgta tccatcaaaa aggtggatga
   120961 tagcgaaaaa aatgccgtga ttacccgaaa tgttacggca aaagaacaag tgattcgctt
   121021 tggctttgat ttctttaaat ttgctggatc agctgcgggc actaccgaaa ctggcttcaa
   121081 tgatctgacc tttaaagtgt cgccattgga agggaccaat gaaatcacag gtgccgaaga
   121141 tgaagcgacc acagcttata acgagcaatt agggtttgat ggttatggca agtttgaaaa
   121201 tcttccttat ggggattatt tacttgaaga agtagaagcc ccagaaggtt ttcaaaagat
   121261 tacgccatta gaaatccgtt ctacttttaa ggaaaacaaa gaagactttg tgaagagtga
   121321 gtatgtcttt accattaccg aacaagacca aaaacaacca attaaaacgg tgaccgttcc
   121381 ttacgagaag ctgacgaaca aagcattttc tgttagtttg aaccgtttaa tgctctatga
   121441 tttgcctgag gaagaagata gtttaacttc tcttgcgact tggaaagacg gaaacaaaga
   121501 attaacttct ctggattcta ccgagctagt tgataaattg agttacaatc tacatgaaat
   121561 caaagaagac tggtatgtgg tagcgcaagc cattgatgtg gatgcgacaa aagctgccca
   121621 agaaaaagat gaaaaagcca aaccagtggt gattgcagaa acaagcgcaa cgttggcgaa
   121681 caaagagaaa acaggaactt ggaaaattca gcataaatta accgccgaac aagttttaaa
   121741 taaaactatt gtcttattca actatgtgta tgaaaataag gaagcttttg aagcaggcga
   121801 taagccagta gcgaaggatg ttagcttgaa taaccaagcc caaactgtca gttgtacagt
   121861 ggaacaccat gtttctatcc aaacaaaggc ccacctagaa aacggttctc agacctttac
   121921 tcatggtgat gtggtggata tgtttgatga tgtgtcgatt actcatgatg tactggatgg
   121981 ctcaaaagaa gctttcgaaa caattctgta tgctttatta ccggatggta caaacaaaga
   122041 aatttggaaa tctggcaaga ttgattatga agtaaatgat aaagaattca ccaaaactgt
   122101 gcttgcgaaa aaagtagata ccggaaaata tccagaagga accaagttta cttttgcgga
   122161 aatcaattac gataaagatg ggaatatcaa tggaaaacac aatgaagatt tgaaagaaaa
   122221 atctcaaacc ttaacaccaa aagaagttcc aaccatacta agtacgccga aacaaccgga
   122281 aacaccaact gttccaagtg gctctcaaga atctagtccc acagtgaaga ccttccctca
   122341 aaccggggag aaaaattcca atgttttact gttcattggt tttactttga tttttgcgac
   122401 ggcgggctat tatttctgga atcgccggaa ctaaggtgat gagatgatac aagtaaatcc
   122461 taagaaccaa cgtgcgcgac cgcctcctaa aaaagtagtc gcgctatttt tgtatccaaa
   122521 actaacaatg aaaagaggaa aagaagatgg aattgaaatt tgtcgtgcca gatatggctg
   122581 aaacctttgg aaagttaagt tatgccggtg aaggagaaat tataacagaa ggatatggac
   122641 ggaatactac ggtgattggt cgcagttatc atttgtattc cagtaagcaa cgggccgatg
   122701 atattgaggt ggtagtagct gcggaagccg gtgaaaagga ttttgatcaa gaccaaccgc
   122761 taaaagccgt gaatccccat ttggttgcca aaggctatga gattgagaat cgtgggttta
   122821 ctgattacgt gttgtatgtt gatgatttag tgaaagcata ggaggaaaag aagatgagat
   122881 taacagaagg tattgtcgta gattcaggtt taacatttgg gaagttgcgt ttttccgcat
   122941 tacgccgaga agtacggaag caaaatgagg atggaacaat tggtaatgag gtaaaagaac
   123001 gaacctataa tttaaaatcc tctgcacaag ggcgaatgat tcaagttagt atcccagcta
   123061 atgtaccctt acgcgagttt gcttatgatg cagaggtaga gttggtcaat ccaatcgtgg
   123121 ataccgttgc caattatgtt tttcgagaag gaactaccgt taattggttc attaaggcgg
   123181 atgatttagt cttgaagcgg cagccgaatc aaggaaatcc tacgaaccaa aatgaaagaa
   123241 agaaataggt gaagattatg gaaattaatg ttgaacatat tttagattgt ctcgatcaat
   123301 atggaaaagg cgagctgact gaggaacaac tcgttaaagc attaacctct gatgaaaaaa
   123361 tgtttctgat tatacatcaa ggtttacttg gagaaaatag cgacagtgaa gaagactctg
   123421 atgtactaga ctggttagga gaagaagagt ctttctttat agttgtcgaa gtaaatgaaa
   123481 acttatgtcg gcaggcagaa tccattttgg aagaaattgg tgtggagatg ccggatgcta
   123541 ttgaaggctt tttaaatcaa ttggttgaaa cgaaacaact cccctcctcg tagcagtaaa
   123601 tgactagcat aactttttga aattgcctaa tgaaatccta ttgggctttt tcgattggag
   123661 gtggaaacca tcaaaatgta caaaggacat cgcatacgcg caggagatca gcacttggtt
   123721 tatcactttg ttcttggctg gctactcgct ctgttcatcg gttggatgag cgtcttttat
   123781 tttcaagagt ttagacaatt tgatatttct aagctatcac tttctactat tgaaatcgtt
   123841 tggtctataa aagatttagt atgtctgctt ggaagtctcg ctttttcagg agctatgata
   123901 ttgctttata ttcacttttt tcttgatcat tggcgaagct tgtggcatcg acaaaagcta
   123961 gctcggatga ttctagagaa ccattggtat gaagtgaaac aaactcaaag tgaaggcttt
   124021 ttcaaagatt tgaatagtag ccgaaccaga gagactatca gttacttccc caaaatctgt
   124081 tatcgaatga aagatggatt actgtctatt cgcgttcaaa tttcacttgg gaaataccaa
   124141 gatcagcttt taaaattgga aaagaagtta gaaagcggac tgtattgtga gttagtagaa
   124201 aaggaactca aagactccta tgtggagtat actttactgt atgatatgat cgccaatcga
   124261 attgggatag acgaagtagt ggcagaaaat gggactctgc gattgatgaa aaatcaagta
   124321 tgggcttatg attctttacc ccatatgtta atcgctggtg gcacgggtgg agggaagacc
   124381 tatttcctcc tcaccattat cgaagcacta ttgaagtcag atgcagaatt gtttatcctc
   124441 gatcccaaaa atgcagattt agctgattta ggtacggtga tgcctcatgt ttattcacaa
   124501 aaggaagaaa tttctgcttg tgtggaagat ttctatgaac gtatgatggc tcgtagcaag
   124561 gcaatgaaag aaatgtctaa ctacaaaaca ggagagaatt atgcctatct tggacttcca
   124621 cccaactttt taatctttga tgaatacgtg gcttatatgg agatgttaac gacgaaagaa
   124681 agtgcggtga ttttgaataa gctcaaacaa atcgtgatgt tgggtcgtca atctggtttc
   124741 tttctgattt tggcttgcca aaggccggat gcgaaatatt taggagacgg aatccgcgat
   124801 caattcaact ttcgcgtggc tttgggtcgt atgagtgaac tcggatattc catgatgttt
   124861 ggggaggtcg aaaaaaactt ctttatgaag cacatcaaag gtcgaggtta tgtggataca
   124921 ggtggcagtg tgattagtga gttttatacg ccacttgtac caaaagggta tgatttctta
   124981 gattcaatta gtaaattaga aaagatgaat gattgagtga tcttcaatac tgactttata
   125041 cttcaagtaa cgtataatac ttttatatag taggaagaaa ggggataatt aatatggaaa
   125101 gtaatgattc ttatttagag tatgcaaaag caaataagga taagtttatt tcttatatta
   125161 tcaaagggaa atcccccgaa gttggacgag acgcagtttt tatggcaggg agtcctgggg
   125221 ctggaaaatc agaggttgcc attggattag ctgagaatta tgataaccat gtgattattg
   125281 atgcggatta ctttcgcacc cagtttcctg attataatgg aaaaaactct agtctctttc
   125341 aaaaagcatc ttcttggttg gtagagcagg catttagata tgtcttagat catggctatt
   125401 cttttattct ggatgcaact tttgcaatat taagtgctga aaaaaatatc tcgcgggcgt
   125461 tgaaaaaaca ttttcgagtg acgattttct atgtttatca agaccctaaa atcgcttgga
   125521 aatttacaca agaacgtgaa attgcagagg gacgtcatgt gccgaaaaag gcatttatta
   125581 acgctttttt caaatcaaga gagaacattg caaaagtaaa gagtaaacat ccagatgtat
   125641 tgcttcatat cataataaaa gattatacga ataatatttc cgaagttcat tatgctacgg
   125701 ataatctaga attattttta ccactagggt atagtaggaa agatttggag gttcaattac
   125761 atgactgaga aagaacaagt aacgaaaatt gtaaagaaat acaataagag cattgcggat
   125821 ttatcggaaa atgctactgc aaaagagttc aaaacggtga ttaaatatgt agccgatcag
   125881 gccaatgaaa aacaacggaa attagttgga ttaaataaaa aatagtagga caaattaata
   125941 atgtatgagc caagagcaaa atgttcttgg cttttttctt tgcaatgaat gaggtaatgt
   126001 atgagatttt tagatttatt cgccggtatt ggtggctttc gtttaggtat ggaacaggcg
   126061 agccatcatt gtatcggttt ttgtgaaatt gataaatttg ctagacgtag ttataaagca
   126121 attcatgata caagtaagga ggtggaaatg catgacatca caagtgtatc agatgagttt
   126181 attcaatccc tcggaccagt ggacatcctt tgcggcggat ttccgtgcca agctttttca
   126241 attgcgggaa agcggcaaag attttccgat actcgaggta ctttattctt tgaaatcgct
   126301 cggttcacca ctcttctccg acctaagctt ttattccttg agaacgtccg aggattgctc
   126361 aatcacgaag gaggggctac gttcgagacg atcctccgaa cgctggatgg attggggtat
   126421 gacgtggagt ggtaggtgct taactcaaag gcctacattc cccaaagccg ggagcggata
   126481 ttccttatcg gacattctcg agacgcatgt accgaacaag tatttcctat cattggaccg
   126541 tcttcaacat ctgatcaaaa catcagaaat ttggtaaata tcaatccttc caatcgagga
   126601 atgggtggac aagtctatgg ttcagatggc gtagcgccaa ccttaacagg tgatgaagga
   126661 atcaaaatcg cactgccagc aagggatgga atctctgtag caggactatt accgggaaag
   126721 tttgaacaag gtaatcgagt ttatgaagtt actggaaccg cccccacctt gtcaacgaaa
   126781 caaggtggta caaaaatcat gattcgaaaa aatgaaacag aatatcaaga ggtgaagcca
   126841 gaagacagtg tgaatctggc ttttcctaat tccacaagtc gccgaggtcg tctgggaaaa
   126901 cagagtgttc ataccttact aacaggagac caacaagcga tcgtcacgga tcagtatcaa
   126961 attcggaagc taacacctag agagtgttgg cgacttcagg gctttcccga ttgggctttt
   127021 gatcgagatt ctcaagtcaa ttcagatagt cagttgtata agcaagccgg aaactctgta
   127081 acagttccgg tcatttttga tattgccaga agattaaaag agttggatgt acatggttta
   127141 tgatgagttg attggagaaa tttattgggt gattggaaag attcagtcag acccagaatt
   127201 agaagaacaa ttgcgacggt taaaatttga tattcgcaag aatggtgtca aagtcgctgg
   127261 cgatccatat ttaatgaatg aggagacgga tgctcgaatt gaaataaatc aagtaattgc
   127321 agaatttgag cggattgcgg accaagcaaa agaaccagat attcgtcaat acttgttaga
   127381 aatgaaagca gagttggaag taaatggtat tacagatgag taacctaaac caacacaact
   127441 gactgttagg cgctgaccgc ggaggattcg cgaagcagaa atcctccgtg gtgctgtgcc
   127501 tgttcatgga cggcgttagc cgaccatgat gtctcacccc cgtatctaac aggggggtac
   127561 aaaaacacaa aaaataagta agcaaccatt aagaatgctt gttgtatcaa agatagtaag
   127621 taatttgtat aggtgttaac tcatttgaaa aagttaacac cttgaatttg gaggtgagaa
   127681 cttggcacaa cggaatttag attatcggct attaaaagac cgacgcaacg aatacggcgt
   127741 ttcacaaaat aaattggcta cggcttgtgg acttagtcgg ccgtacttaa atcagataga
   127801 aaatggtggc gtaaccgcat ctataaaaac catgaggaaa atttttgacc aactggaaag
   127861 ctttaatccc gatttgcctt tgacgttact gtttgactat gtaaggattc gctttcccac
   127921 aacggatgca cgaaaaatta ttcaagaaat tctccatttg aaatttgagt atatgctcca
   127981 tgaagattat gccttttact cctatcaaga acagtatgtc atgggtgata ttgtggtgat
   128041 gttgtctcat gaagaagata aaggtgt
//
LOCUS       DAFENC010000002       120744 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.002, whole genome shotgun sequence.
ACCESSION   DAFENC010000002
VERSION     DAFENC010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 120744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 120744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..120744
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.002"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(134..928)
                     /locus_tag="LP493_000119"
     CDS             complement(134..928)
                     /locus_tag="LP493_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PH domain-containing protein"
                     /protein_id="HBL2132304.1"
                     /translation="MSKQCAKCGGKIGLTSYKIKDKQIVCGNCMKKAGYGMTTPYKII
                     RSLNLEDLDKDPSEKRKLNISDHTAQNNHDIGNDRMRTTEEMVEFCLKYGYGKGMTKK
                     WTTHHFNLISDQLNSDEYVIFCFVGLHNYISSTKHDNNYAYALTNKRLIVAQQKMIGN
                     NVQSIILDNLNNISKKRGVLLGTLTIDTLGKVLNVAVDKDTVDRISDSLNEIIYNLKR
                     RNISATNSNTSTISSASEIRKYKELLDDGIITEEEFNKKKQELLDL"
     gene            1574..4381
                     /locus_tag="LP493_000120"
     CDS             1574..4381
                     /locus_tag="LP493_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL2132305.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            4572..5063
                     /locus_tag="LP493_000121"
     CDS             4572..5063
                     /locus_tag="LP493_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2132306.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            5166..6155
                     /gene="manX"
                     /locus_tag="LP493_000122"
     CDS             5166..6155
                     /gene="manX"
                     /locus_tag="LP493_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HBL2132307.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSIGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            6188..6991
                     /locus_tag="LP493_000123"
     CDS             6188..6991
                     /locus_tag="LP493_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HBL2132308.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            7012..7926
                     /locus_tag="LP493_000124"
     CDS             7012..7926
                     /locus_tag="LP493_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HBL2132309.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVERWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            8009..8383
                     /locus_tag="LP493_000125"
     CDS             8009..8383
                     /locus_tag="LP493_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HBL2132310.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            8522..8767
                     /locus_tag="LP493_000126"
     CDS             8522..8767
                     /locus_tag="LP493_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBL2132311.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            8939..10003
                     /locus_tag="LP493_000127"
     CDS             8939..10003
                     /locus_tag="LP493_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBL2132312.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            10249..10674
                     /locus_tag="LP493_000128"
     CDS             10249..10674
                     /locus_tag="LP493_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBL2132313.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            10667..11116
                     /gene="nusB"
                     /locus_tag="LP493_000129"
     CDS             10667..11116
                     /gene="nusB"
                     /locus_tag="LP493_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HBL2132314.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            11213..12067
                     /locus_tag="LP493_000130"
     CDS             11213..12067
                     /locus_tag="LP493_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HBL2132315.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            12068..13405
                     /locus_tag="LP493_000131"
     CDS             12068..13405
                     /locus_tag="LP493_000131"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HBL2132316.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            13410..13634
                     /locus_tag="LP493_000132"
     CDS             13410..13634
                     /locus_tag="LP493_000132"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HBL2132317.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            13636..14526
                     /locus_tag="LP493_000133"
     CDS             13636..14526
                     /locus_tag="LP493_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBL2132318.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            14535..15353
                     /locus_tag="LP493_000134"
     CDS             14535..15353
                     /locus_tag="LP493_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HBL2132319.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            15460..15909
                     /locus_tag="LP493_000135"
     CDS             15460..15909
                     /locus_tag="LP493_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBL2132320.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            15927..17609
                     /gene="recN"
                     /locus_tag="LP493_000136"
     CDS             15927..17609
                     /gene="recN"
                     /locus_tag="LP493_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HBL2132321.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(17664..17780)
                     /locus_tag="LP493_000137"
     CDS             complement(17664..17780)
                     /locus_tag="LP493_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HBL2132322.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(17853..18809)
                     /locus_tag="LP493_000138"
     CDS             complement(17853..18809)
                     /locus_tag="LP493_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBL2132323.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            18980..19348
                     /locus_tag="LP493_000139"
     CDS             18980..19348
                     /locus_tag="LP493_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HBL2132324.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            19518..19949
                     /gene="mraZ"
                     /locus_tag="LP493_000140"
     CDS             19518..19949
                     /gene="mraZ"
                     /locus_tag="LP493_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HBL2132325.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            19970..20929
                     /gene="rsmH"
                     /locus_tag="LP493_000141"
     CDS             19970..20929
                     /gene="rsmH"
                     /locus_tag="LP493_000141"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HBL2132326.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            20934..21335
                     /gene="ftsL"
                     /locus_tag="LP493_000142"
     CDS             20934..21335
                     /gene="ftsL"
                     /locus_tag="LP493_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HBL2132327.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            21336..23528
                     /locus_tag="LP493_000143"
     CDS             21336..23528
                     /locus_tag="LP493_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBL2132328.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            23554..24516
                     /locus_tag="LP493_000144"
     CDS             23554..24516
                     /locus_tag="LP493_000144"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HBL2132329.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            24530..25891
                     /locus_tag="LP493_000145"
     CDS             24530..25891
                     /locus_tag="LP493_000145"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HBL2132330.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            25917..27005
                     /gene="murG"
                     /locus_tag="LP493_000146"
     CDS             25917..27005
                     /gene="murG"
                     /locus_tag="LP493_000146"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBL2132331.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            27020..28240
                     /locus_tag="LP493_000147"
     CDS             27020..28240
                     /locus_tag="LP493_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HBL2132332.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            28396..29721
                     /gene="ftsA"
                     /locus_tag="LP493_000148"
     CDS             28396..29721
                     /gene="ftsA"
                     /locus_tag="LP493_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HBL2132333.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            29744..30985
                     /gene="ftsZ"
                     /locus_tag="LP493_000149"
     CDS             29744..30985
                     /gene="ftsZ"
                     /locus_tag="LP493_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HBL2132334.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            31002..31679
                     /locus_tag="LP493_000150"
     CDS             31002..31679
                     /locus_tag="LP493_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HBL2132335.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            31693..32292
                     /locus_tag="LP493_000151"
     CDS             31693..32292
                     /locus_tag="LP493_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HBL2132336.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            32307..32594
                     /locus_tag="LP493_000152"
     CDS             32307..32594
                     /locus_tag="LP493_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HBL2132337.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            32627..33424
                     /locus_tag="LP493_000153"
     CDS             32627..33424
                     /locus_tag="LP493_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HBL2132338.1"
                     /translation="MGGENFDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFL
                     DPRQSYILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYP
                     SKFASLSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVA
                     VRLEPIKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNW
                     TENTRPDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            33445..34152
                     /locus_tag="LP493_000154"
     CDS             33445..34152
                     /locus_tag="LP493_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HBL2132339.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            34414..37212
                     /gene="ileS"
                     /locus_tag="LP493_000155"
     CDS             34414..37212
                     /gene="ileS"
                     /locus_tag="LP493_000155"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HBL2132340.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMCMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(37261..38787)
                     /locus_tag="LP493_000156"
     CDS             complement(37261..38787)
                     /locus_tag="LP493_000156"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HBL2132341.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(38802..39449)
                     /locus_tag="LP493_000157"
     CDS             complement(38802..39449)
                     /locus_tag="LP493_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HBL2132342.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(39633..39962)
                     /locus_tag="LP493_000158"
     CDS             complement(39633..39962)
                     /locus_tag="LP493_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HBL2132343.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            40139..40867
                     /gene="sfsA"
                     /locus_tag="LP493_000159"
     CDS             40139..40867
                     /gene="sfsA"
                     /locus_tag="LP493_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HBL2132344.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            40883..41896
                     /locus_tag="LP493_000160"
     CDS             40883..41896
                     /locus_tag="LP493_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL2132345.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            41896..43173
                     /locus_tag="LP493_000161"
     CDS             41896..43173
                     /locus_tag="LP493_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBL2132346.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            43236..45938
                     /locus_tag="LP493_000162"
     CDS             43236..45938
                     /locus_tag="LP493_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL2132347.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            46090..46407
                     /locus_tag="LP493_000163"
     CDS             46090..46407
                     /locus_tag="LP493_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2132348.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            46437..46757
                     /locus_tag="LP493_000164"
     CDS             46437..46757
                     /locus_tag="LP493_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBL2132349.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            46865..48325
                     /locus_tag="LP493_000165"
     CDS             46865..48325
                     /locus_tag="LP493_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2132350.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            48393..48614
                     /locus_tag="LP493_000166"
     CDS             48393..48614
                     /locus_tag="LP493_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132351.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            48645..48827
                     /locus_tag="LP493_000167"
     CDS             48645..48827
                     /locus_tag="LP493_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HBL2132352.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            48827..49240
                     /locus_tag="LP493_000168"
     CDS             48827..49240
                     /locus_tag="LP493_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HBL2132353.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            49363..50544
                     /locus_tag="LP493_000169"
     CDS             49363..50544
                     /locus_tag="LP493_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2132354.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(50615..50779)
                     /locus_tag="LP493_000170"
     CDS             complement(50615..50779)
                     /locus_tag="LP493_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132355.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            51205..51278
                     /locus_tag="LP493_000171"
     tRNA            51205..51278
                     /locus_tag="LP493_000171"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:51239..51241,aa:Arg,seq:cct)
     gene            51605..52570
                     /locus_tag="LP493_000172"
     CDS             51605..52570
                     /locus_tag="LP493_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004613268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBL2132356.1"
                     /translation="MVKQQCLFGTLLSIKVPGRHFLFPESWRKGVKMTEPNRQSGENE
                     ERIIEIEIERLRPFKEHPFQVKDDKEMFLLQESIEKYGILNPLIVRPVPDGYYEIISG
                     HRRKHAAEKLGYRKVPVIIRVLSEDDSILSMVDSNLHRERISYSEKAFAYKLKNDVLK
                     RKSGRKKSQVDHKTPRKRAIEIISEDCGDSPKQVQRYISLTKLIPEMLQKLDDEIISF
                     CPAVEIAALSEKEQRELLVAMEYAQAIPSLSQAQRIRQLSKEKQLSLEKMEEIMCEVK
                     KGEITRVAFTNEQLHKYFPNSYTPAMMKREILALLKLWKKESWES"
     gene            52585..53370
                     /locus_tag="LP493_000173"
     CDS             52585..53370
                     /locus_tag="LP493_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015535366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBL2132357.1"
                     /translation="MCKVISVVNQKGGVGKTTTTVNVGIGLAREGKKVLLIDADPQGS
                     LTASLGYEEPDDLRITLATIMMEVINEEEISLEDGILHHQENVDLLPANIELSALEVT
                     MGNVMSREMIMKEYIDAIRCRYDYILIDCMPSLGMMTINALVSSDSVLIPVQAAYLPV
                     KGLQQLIKTILTVKKRLNRKLAIEGILLTMVDFRTNYARDIASRVHTTYGSQIEVFEN
                     VIPMSVKAAETSAEGKSIYMHCPKGKVAEAYKNLTQEVLKNEK"
     gene            53360..54265
                     /locus_tag="LP493_000174"
     CDS             53360..54265
                     /locus_tag="LP493_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015535367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBL2132358.1"
                     /translation="MKNRSGEKIKLASIDELLGVVNEESAMEIEISKIHPFKNHPFKV
                     LDDEKMQDLVESVRINGVLTPVLLRMDDNEEYEMVSGHRRMHAAQLAGLTTIPAIVRE
                     LSDDDAVIAMVDANIQREELLPSEKAFAYKMKMDAMRRTAGRPTKENPRQNVGNYETA
                     DLIGKDNGESGRQVQRYIRLTELIPELLDLVDKKKLQFTVAIDISYIDKEVQEWIYEY
                     ISDTGFIKPKQIAALRNQLNDGPINQIQMLSIFNNCVIAKKVSRSLTFSEKKLTKYFP
                     DDYTAKDMEQVIESLLEKWMQEQSC"
     gene            54344..55342
                     /locus_tag="LP493_000175"
     CDS             54344..55342
                     /locus_tag="LP493_000175"
                     /inference="COORDINATES: protein motif:HMM:NF018653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBL2132359.1"
                     /translation="MEKKMTFNYFYGTEADQFSFYRIPKALFTDSYFKDLSSDAKILY
                     GLMLDRMSLSIKNQWFDDKNRAYIYFSIEDIMELLNCGRNKAIKSMRELDDETGIGLI
                     EKRRQGFGKVNVIYVKTFMPEKTDEKKFEEELKKFKKQTSVENEEPAEVYNSNFMKSQ
                     NQTSRSPENKLQEVYISNPNNTNLSDTEMNDNKSNPIISVDEKRFDSDNRSEDYQAYE
                     NLVKETIDYESLEVTHHDDMRQVDEIVNLIVETVMCKNDKILIASNWYPASLVKKKFL
                     MLTYSHIEYVLHCMSGNTTKVKNIKKYLLAALFNAPSTMNGYYQAEVNHDMPGLVR"
     gene            55352..55648
                     /locus_tag="LP493_000176"
     CDS             55352..55648
                     /locus_tag="LP493_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015526518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132360.1"
                     /translation="MFILKLVGKILLLPVWLILFVIGLAVKMTVQTYAVVRGILGFIF
                     TLLIIATAYCYHDWVQVAFLFSLSVILYLILFAGVFVDTVLDMTRERIIDFIIS"
     gene            55656..55868
                     /locus_tag="LP493_000177"
                     /pseudo
     CDS             55656..55868
                     /locus_tag="LP493_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005334861.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            55992..56666
                     /locus_tag="LP493_000178"
     CDS             55992..56666
                     /locus_tag="LP493_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2132361.1"
                     /translation="MNYKILMVDDDRELLKMLNQYFTLKNYTVMIAENGIEAMEKISA
                     NPDIILLDVNMPGMDGIEVCRRIRDMVSCPIIFLTAKVEEQDRVMGLLSGGDDYVLKP
                     FSLKELDARIIAHLKREERLHRKKEQRFYGELVIDYASKCVHIKGNALELTKLEYEII
                     EFLSMNPEMVFDKERIYEKIGGYDAEGDSRVVTELIRRIRKKMKMYSEHEYIATVWGR
                     GYKWAK"
     gene            56654..57835
                     /locus_tag="LP493_000179"
     CDS             56654..57835
                     /locus_tag="LP493_000179"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012722.1,HMM:NF014567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL2132362.1"
                     /translation="MGKIKNLSLRKTIVLYMIISLIISFYLSALIMRIASTVQNNIWW
                     NYVDQEEYFEMAEGDGRRYLPDVPRPHSYEMKEFDYHVSEICDFLQTFTVLIVSVAGS
                     IIAVFLFYKHKLKCPIEELELASRQVGRNNLDFHITYENEDEMGGLCKEFERMRGQLA
                     ENNQQLWKMLEEEKALRAAIAHDIRSPLSVLEGYQEMLSEYLPKKEINMEQALEMVNE
                     SKKQIERMDIFVETMRKMSSLDTRELVAEEITSKQVEIDVRAEMNVFRKKFGKLYELE
                     CSETEEKFSGDKEVILEVIENLLSNAFRYAKTKVEMEVFLTCSELQIRIKDDGVGFTI
                     DKQKATELFYQQNVKDSLKHSGMGMYISRLYCEKHGGQLLIENEKQSGAVITAVFHRI
                     A"
     gene            57919..58983
                     /locus_tag="LP493_000180"
     CDS             57919..58983
                     /locus_tag="LP493_000180"
                     /inference="COORDINATES: protein motif:HMM:NF024091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBL2132363.1"
                     /translation="MIAIFKREIRNYLKRPLFWVGVLLVIYGVFNATSPYLTTHYLTT
                     GEEIINDQSNTSVEGEVYEGYIPATPEKHREVWHEKVKIKLTDVFGLTDSEAQNVIEK
                     LESMNLKEAYAYLEQEYDWYGARYLYEDSTYYKGTAEEINAYLDKKLEDKTFSFYYAR
                     KFADFAGLYMVFFAIIMLAVLFLQDTKKHTYELLHTKPVTAGKYVMGKVSAGFTICLL
                     VLTILNILFWVLCRIYTKDSGFEVRLWDFVASTVLYILPNMLMIVSIYTLISLIFKNP
                     LPGVPLLILYMVYSNLGGTNAEGVYGYWGKPLAIMVRFPGQLFDTTPPPMALLNQSFL
                     IIVSVVIILISIQIWKRRRI"
     gene            58984..59643
                     /locus_tag="LP493_000181"
     CDS             58984..59643
                     /locus_tag="LP493_000181"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132364.1"
                     /translation="MKKEMKIVLPFYKIAYAVSFVVILSVIRAVVFTYEIGLSIEPPF
                     AILTAVFCADTYVQEITSNRSEVQRLYQIKKRIYSIIQRLMIQGTFLLLLAVLGYGLF
                     FAFQKPITHPVTESEILQFITCFGAIVVTIFFWGILANTLSMLFRNMWMGIGSSLLIW
                     VATNSTGGDKLFGAWNLFSYSFRDIENTADITWLYGKGLCICIGLILLLALPKIVRKR
                     G"
     gene            59648..60523
                     /locus_tag="LP493_000182"
     CDS             59648..60523
                     /locus_tag="LP493_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005333452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2132365.1"
                     /translation="MSIHIEDLTVRFKNSVTAIDHADLDIPNGIFGLLGENGAGKTTL
                     MRVLTTVLKPTNGMVTLDGILYSEGNYEKIQRKIGYLPQEIELYPNLTVQECLEYMGD
                     LAGVPKAECRKRIDYYLKKTSLIEHRKKKMKQLSGGMKRRVGLVQALLNEPEFLIVDE
                     PTTGLDPEERIRIRNLLVDFSENRTVLFSTHVVEDLAATCNQLAIMHKGRFLYAGSMK
                     NLTEEAQGKIWICKVPDERKAREVEQKYRITSKQYVEGGLQLRVISEIQPELECMSIP
                     ATLEDAYIYVTNQYE"
     gene            complement(60650..60943)
                     /locus_tag="LP493_000183"
     CDS             complement(60650..60943)
                     /locus_tag="LP493_000183"
                     /inference="COORDINATES: protein motif:HMM:NF013100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132366.1"
                     /translation="MYTNWYFESIDKQLGSSTINSYLQQIGYGNKNISGDFSSYWMQS
                     SLKISPVEQVELLKNLYRNNFNFTPANIHAVKNSIHLTASENGEFMEKPEPDE"
     gene            60989..61198
                     /locus_tag="LP493_000184"
     CDS             60989..61198
                     /locus_tag="LP493_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003864624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132367.1"
                     /translation="MKSHKYWSIGALITMLGTFYTGYKGSKEGHKYFAASSLLCMIMA
                     IYTGHKMISGKSRKKKEVSVESVED"
     gene            complement(61301..61954)
                     /locus_tag="LP493_000185"
     CDS             complement(61301..61954)
                     /locus_tag="LP493_000185"
                     /inference="COORDINATES: protein motif:HMM:NF025711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpXC domain-containing protein"
                     /protein_id="HBL2132368.1"
                     /translation="MSRHHIEKVTCPSCHHEGDFELWDSINTALDPEMKEKVLNQSIF
                     LYTCPSCGETFRLNYSTLYHQMEDLVMIYLVPESEVKKTYEIFYEKNALADYRTEKYL
                     YRIVTSANQLVEKIQIFDADKDDRVMELVKLLATDSILKNDPDIEFDELRFAVDDDGT
                     NILVIINKGEITGAVDIDNMYEFASSHCNDFKDLRDDDEIVINREWILNKLAEAENE"
     gene            complement(62020..62460)
                     /locus_tag="LP493_000186"
     CDS             complement(62020..62460)
                     /locus_tag="LP493_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015527715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBL2132369.1"
                     /translation="MNQMNIVVGETSRYKTLKGYCFMSCKTIYVMISSFLSEEEKMIV
                     AAHELGHIILHRSQLKMAPMQDDTLYNMTDNTEYQANLFAADLLIDDEEIEDMVQNED
                     LDYFGLCSSLNATPELMSFKLYSLTKRGQAYHMPMEIQSNFLAK"
     gene            complement(62628..63047)
                     /locus_tag="LP493_000187"
     CDS             complement(62628..63047)
                     /locus_tag="LP493_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015535375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2132370.1"
                     /translation="MTFGEKVRSLRKEKKMSQQELASMVGVSYRTIRSWEVEGRFPKQ
                     NVLYQKLADALQCDVSYLMSEDEAFITEASEQFGNRGARQAQQILEQAAAMFAGGSLT
                     DEDKIAFMDEIQSLYLDSKRRAKKFTPKKYLKNQEEK"
     gene            63374..64624
                     /locus_tag="LP493_000188"
     CDS             63374..64624
                     /locus_tag="LP493_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003670785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein"
                     /protein_id="HBL2132371.1"
                     /translation="MCIDLKSFYASVECVERGLDPFKANLVVADPTRSKSTICLAITP
                     AMKSLGIKNRCRIHEIPDCVKYITAMPRMQLYMDYSAKIYGIYLRYVSKEDIHVYSVD
                     ECFIDVTNYLQLYHLTAKEMAVKLMQEVMEETGITATAGVGTNLYLAKIAMDIVAKHV
                     DDHIGILDEFSYREQLWDHKPLSDFWRIGSRTEKKLAGYGIHTMGDIAMASLRSEDWL
                     YKMFGIDAELLIDHAWGYETCRMSDIKNYHSEEHSLSNGQVLMRNYSFEEALVIVREM
                     TDNLALDLFEKGLVTSSLTLWIAYDHRYEHEASKGTVKLERGSNSSKKIMDAVEDLYL
                     RIADRYTGIRRIEVCANRVAPENYVQYSLFDDPKQTDKERHLQEAVLNVKQRYGKNAI
                     MRGSNLLECSTYRERNEQIGGHRA"
     gene            64702..65055
                     /locus_tag="LP493_000189"
     CDS             64702..65055
                     /locus_tag="LP493_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005334842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132372.1"
                     /translation="MDVGRRAKQFAPFAALRGLDETIRQQEIIYESKRDLSEEKKNEL
                     DMKLRILAYGMKIQATYFQKSWKDPSVGQYHTLSGTVEFFDPSVHLRIDDTEIQIQDI
                     CDLTGDVFETIEISC"
     gene            65290..65517
                     /locus_tag="LP493_000190"
     CDS             65290..65517
                     /locus_tag="LP493_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005334838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132373.1"
                     /translation="MGSGAIKWHVHCSVCGAFIEKSAQSDSEVECKKCRSTLEIFVKD
                     DMVSVRPIHIRDEQLKSRMRTYSRKMMNQGS"
     gene            66176..66796
                     /locus_tag="LP493_000191"
     CDS             66176..66796
                     /locus_tag="LP493_000191"
                     /inference="COORDINATES: protein motif:HMM:TIGR02937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBL2132374.1"
                     /translation="MLTLKELKKIVKVADMEKRIPSVKSLKEHKVVVKEMINADTTIS
                     VYDHGYVLYTAGNQSTVFPLHSCDDYEYVSVTGDNKEFNKEFFDNENWYIRLLMEAED
                     RMAYSQSKISTNHGVFSNSDVTDDAEIMRGSSKDFVDDVIDREILNALIKELTERQKT
                     VLNLVYFEEMRQQDVADYLGIKQQSVNDLLNRALKTMKKKAENEEF"
     gene            67269..72530
                     /locus_tag="LP493_000192"
     CDS             67269..72530
                     /locus_tag="LP493_000192"
                     /inference="COORDINATES: protein motif:HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBL2132375.1"
                     /translation="MNVKKKARRVMSGLLTAVTVLSTVLSPAVAYASDDAGSVKKIPY
                     YEEIKDQLDEDEVVTAKDYEIKVGDNFDVKSDYTGLTIQDDSKVKVTFQEAKDTDGND
                     FSTDYANSYKAVYYVEPQTTDHPTYQINRKIVVKEADQQKDSQSESSSDQDAGSSDKT
                     ETEDSEADSSTEGTDAADTESKTELTEKEFDAEIEATEDQETVDPETGITLSEVMQEA
                     VDQEVALADLEAGESITFDMPMMLASGETGTKSVTVTAGSWYYYADYGLGSYLTCPYY
                     VKWGSINATAYCVEPSKKGPGNGTYTIQKLADGKTLAKVCYYGTKASDENGFFDEKHP
                     DFPAGKRFIITHLAAAYANGSSDWASGTNATGKNLAMELYNYCVNMPDIPSVDMSFSE
                     SNVKAYVEGNSQRTSVITFKADKLQTITFKLPSGVKLVNVTTGKTSAAGASVEISGGT
                     QFYLTALLDQAESVSATFSSRMKGSIDKEYSAYKIVTGSGTQDLALVFGEGVGNEKYV
                     DFKVTWTKECKVSIVKKDQDTGNALAGAVYGIYSDASCTKLIAEMPATDQNSASQLTM
                     EKTQEVVYLKEISVPTGYQIDTKSYNVTLAIGKTTTKNVTDKRVNAKINIAKQDAETG
                     NAAQGDATLEGAVYGLYAREDIVHPDGRTGTIHKKDSLITSLTTDKNGEASVSDLYLG
                     KYYLKELSAPVGYVLDPTEHEVDCTYEGATVPTVERTSVCKETVVKQPFQIIKAANNG
                     KTDADLLKGVGFSAWLVSDLKVKADGSYDFDSARPVVLTADGQAEMFTDEKGYARSIP
                     LPYGTYVVRETTSKHNYAPVDDFIVKITENHPDTPQTWRVLLDKEFKAKLKIIKKDAE
                     TQKSVLLANTEFKIYDLDNQKYVEQTTSYPKPTVHKSYFTNEEGYLVLPKNLKPGNYR
                     IEEVTAPDGYTISKNYVTVAVDTDTAYLTDPVTGDAVIAVEYTNAPVKGQLKIYKQGE
                     VLKGFDKDFQYEMAGLAGAEFEVYAAEDIYTADHQVDADGQRTLYFAKDALVATVTTD
                     ADGYATVKNLPLGRYYVKEKNAPDTHVLNTVPENVEFAYADQDTAVIEKEISVTDERQ
                     KVSITVEKQDAETGNTVAGAVFGIYNAKDIQTKDGKVIVKVDTLLQEMTSDEKGQAAC
                     TLDLPLGSYYVKELKAPNGFVSSDEVLRFDASYQGQDVQTVTLKSVKKNQPTTVEITK
                     SDATTGVELDGAYLKVTDKDGNVVDSWTSSKDAPHVIKYLKVGETYTLHEEFAPHGYL
                     VANDVTFTVKDTGEVQKVEMKDEVPVGELIINKKGEFLDSVTLADKVKGVVEHIFNYV
                     TGKLTDVTFEVYAEEDIKAADGVSDDYYKKDELIATIKTDETGIAKLENLPLGKYYVK
                     ETGTAYGHVLDGEIRHVDLTYVDQNTPVVVYDKDWQNNRQRVEVSVLKKEKDSDRTLE
                     GAIFGLFAKEDIKSETTGKVLIEADEIIELKSTDEEGKITFVADLPIGATYYVKELYA
                     PDGFVTNDEVKEFTFEYVGENQPTVTYDFTFDNQPTVVEFAKSSLTTGKELPGCKLKV
                     VDSDGNIVDEWTSGKEAHVIRELTVGKEYTLVETKPADGYVTAESVKFTIKDTADVQK
                     VEMKDDVTKVKISKQDIAGKELPGAKLTILDQDGKVVESWTSTEKAHYIEMLPIGKYT
                     LREETAPDGYLVAKDVEFEVKDTGEVQHVTMVDEEKPAEKTPEGGKPVSDSPKTGDNT
                     NLWLWFMLLGIGATGTGALAFMRKKKH"
     gene            72599..72745
                     /locus_tag="LP493_000193"
     CDS             72599..72745
                     /locus_tag="LP493_000193"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132376.1"
                     /translation="MRNIIIFVALLGAAAIFTVLYCLIAAGSQAEKKLTEIMRKEEER
                     NEDK"
     gene            72732..73010
                     /locus_tag="LP493_000194"
     CDS             72732..73010
                     /locus_tag="LP493_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003864611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132377.1"
                     /translation="MKTNKDLIIEPNAAIEGRKYSEEKPWSCKYCYWWEGKKKGCSLK
                     QCHYLLAEKKKAVKTTPCSGCPYGKHVPCIGYCIARLHSEMKGKKGRG"
     gene            73011..73574
                     /locus_tag="LP493_000195"
     CDS             73011..73574
                     /locus_tag="LP493_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005334825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HBL2132378.1"
                     /translation="MQEEVNQKVISLSIQGVKITASVLKAALRKFLEMDNRRKQKATQ
                     VKMAEKTGRAQEKGREQARKKIEKKKPHGKQTIKQLNAQGVQLSNLKITDENIKSFDR
                     VARKYGIDYSLKKDVGADPPKYLVFFKAKDVDVMTAAFREYAGVELKKKQVKKPSVRK
                     KLQKSVERKAKHRQRVKQRQKSRGQER"
     gene            73574..75394
                     /locus_tag="LP493_000196"
     CDS             73574..75394
                     /locus_tag="LP493_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBL2132379.1"
                     /translation="MREKLQKIQVKRLVILNLPYFFIFYVADKGSWLYRHCLGESMVQ
                     RLGVMLVNFRLAFLSWLPSIALQDLTVGVLVASALKLVVYYRSKNAKKFRQGVEYGSA
                     RWGNRKDIEPFMDPVFENNVILTETERLTMNSRPKAPKYARNKNVIVIGGSGSGKTRF
                     YVKPNLMQMTDHVSYVVTDPKGTIIVECGKMLVNGGYRIKVLNTINFKKSMHYNPFHY
                     IRSEKDILKLVNTIIANTKGEGEKSTEDFWVKAERLLYSALIGYIWYEAPEEEQNFST
                     LLEFINASETREDDEEFKNAVDELFEELEAENPEHFAVRQYRKYKLAAGKTAKSILIS
                     CGARLAPFDIQELREIMSYDEMELDMIGDQRTAMFVIISDTDDTFNFVVAIMYTQLFN
                     LLCDKADDEHGGRLPYHVRLLLDEFSNIGQIPKFDKLIATIRSREISASIILQSQSQL
                     KTIYKDAAETITGNCDTVLFLGGKESSTLKEISETLGKETIDLYNTSDTRGSNRSYGL
                     NYQKTGKELMSRDELAVMDGEKCILQLRGVRPFLSNKYDITKHKRYKELADFNKNNAF
                     DVEKYLAHRLVMSEDTEFEMYEVTVTQEDVSVIEAEEGED"
     gene            75523..75738
                     /locus_tag="LP493_000197"
     CDS             75523..75738
                     /locus_tag="LP493_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016147847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HBL2132380.1"
                     /translation="MAFFSSAINILQTLVVAIGAGLGVWGVINLMEGYGNDNPGAKSQ
                     GIKQLMSGGGVILIGTQLIPLLSGLFG"
     gene            75758..76630
                     /locus_tag="LP493_000198"
     CDS             75758..76630
                     /locus_tag="LP493_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005423572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132381.1"
                     /translation="MFSQIFDAIEEWMRELLTGMITSNLDTMFTDVNQKTGEIATQVG
                     QTPQGWNGSIFSMIRNLSDSVIMPIAGIIITLVLCYELISMLTERNNMHDIDTWMFFK
                     YFVKMWIAVYLVSNTFTITMAVFDVGQHVVNSAAGVISGSTAIDISSALTDLSATLES
                     MEIGELVVLALETLIAGFCMRILSVLITVIMYGRMIEIYLYTSVAPIPFATMSNREWG
                     QIGTNYFRGLFALAFQAFLMMVCVAIYAVLVAGIQYSDNLSSSLFGVMAYTVILCYSL
                     FKTASLSKSIFNAH"
     gene            76653..77042
                     /locus_tag="LP493_000199"
     CDS             76653..77042
                     /locus_tag="LP493_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015514792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HBL2132382.1"
                     /translation="MAYVSVPKDLTKVKNKVAFNLTKRQLICIGIGAAMGIPSYFLLR
                     NVMGNSNAATVMVLLMLPAFLFAMYEKDGMHLEDVLMHMIRVKFLRPPVRKYETENYY
                     ETDPEQIRQSPDAGKPKGGKTVAKKEK"
     gene            76939..79080
                     /locus_tag="LP493_000200"
     CDS             76939..79080
                     /locus_tag="LP493_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBL2132383.1"
                     /translation="MRLKTIMKQIRNRSDSHRMQENRKEEKRLRKKKNKKTVADTGYK
                     KVDRKEKKKKEKQEEKRRKKKLSVQQSIAYKEMGRDGICRVQGKTYSKCIRFYDINYQ
                     LAQNEDKNAIFENWCDFLNYFDASIHFQLSFINHKSSMKEFEQVIRIRPQDDAFDDVR
                     MEYAKMLKQQLAKGNNGLVKSKYITFSIEADNIREAKPKLERIESDILNNFKILGVPA
                     YPLNGVERLQILYETFNPDNMTDFQFDYGSMIRTGLNTKDYVAPTSFVFKDRNTFRMG
                     NTIGAVSYLQILAPELTDKMLAEFLDIDKNLIVNLHVQSVDQMKAIKLVKSKVTDINR
                     MKIEEQKKAVRSGYDMDIIPSDLNTYGGEAKRLLEDLQSRNERMFLVTALFLNTAKTK
                     QALDNAIFQTAGIAQKYNCVLKRLDYQQEEGLMSSVPLGVNHIPIRRALTTTSTAIFV
                     PFTTQELFMAGESLYYGLNALSNNMIMVDRKKLKNPNGLILGTPGSGKSFAAKREITN
                     AFFVTKDDIIIGDPEGEYYPLVHALGGQVVHISPTSKDYINPMDINMDYSDDDNPLGV
                     KSDFVLSLCELIMGSRDGIEAEEKSVIDRCLPLVYQKYFADPKPENMPVLGDLYDCLR
                     KQKEPQAQRIATALEIYVNGSLKVFNHRTNVELNNRIVCFDIKELGKQLKKIGMLIVQ
                     DQVWNRVTINRGIKSTRYYIDEFHRTRRSAC"
     gene            79790..81727
                     /gene="ltrA"
                     /locus_tag="LP493_000201"
     CDS             79790..81727
                     /gene="ltrA"
                     /locus_tag="LP493_000201"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBL2132384.1"
                     /translation="MLTMQRKELLKKSAIRYAEYYGMVEVQDALYADSASEKIFTNLI
                     SIIGSDANIKMAYRNLKSNKGSSTPGVDGKTFKDLAEMSEEALVQCVRDKILNYQPKA
                     VRRVYIPKPNGKMRPLGIPTVLDRIVQQSVLQVMEPICEAKFYRHSYGFRPNRSTKNA
                     VAVCYKLAQVDGFHYVVDVDIKGFFDNVDHGKLLKQIWTMGIRDKRLISLIGKMLKAP
                     IEENGVRTVPDKGTPQGGVLSPLLANIVLNELDWWIASQWEEMPAKHPLQSDIYMNKN
                     GTPNKGNLYKKLRQSRLKECHIVRYADDFKIFCRSYSDASKLKHAVEQWLMDRLKLET
                     SPDKSRITNLTKGYSDFLGIKFKLYKKGKKWSIKSHMTDKAINSQRVKLKNAMAQACK
                     SHESEQSQHDDLIRYNQAVIGMHQYYNMATMINADVHRLFPSIDITMKTRLNSRADLS
                     KEKPPTLKGAMDEYFYQKYGESKQVRYINGMIVVPVAYCRTQNPMFYRVDTNRYTPQG
                     RERIHRMLAKSEYGETLLKLSRDNDTNHSIEFCDNRLSRFVASKGKCELSKVSLAFED
                     VECIYLNPPSQGGTDEYANLRIVHKDIKSLIYSNDVKIIKSLIDLFDCRAPAKIAKLN
                     KWRAKAGLEAINLITINQTLK"
     gene            81837..82241
                     /locus_tag="LP493_000202"
                     /pseudo
     CDS             81837..82241
                     /locus_tag="LP493_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019034967.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
     gene            82225..82683
                     /locus_tag="LP493_000203"
     CDS             82225..82683
                     /locus_tag="LP493_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005423581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132385.1"
                     /translation="MKEIDKIRIRQWNQDNPYIQMKNLENAQPGYRVHTVNDDHHLYE
                     LPLETQNIILDWVFWNFYPAQKIYPHLTSDDLKEVLYKRTQIHLHNNQFKEAMLINGF
                     WPRDPSELNWVFHIQASSPAIRTQADGYPGIPIIGRQELNEYRKKSCARR"
     gene            83425..84978
                     /locus_tag="LP493_000204"
     CDS             83425..84978
                     /locus_tag="LP493_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBL2132386.1"
                     /translation="MEGVKNAETVKKAEQKRHFYNRFFQKKRYKDAYRAARAGKSADS
                     LGGATTIAGVENMTVKAKIALKEIIKRNRAMFAGIGIFALLFLVISVSLGSCSASIEG
                     AGSVIGITTYPSSDEDIYAAENRYAALESALNQQINEMERRHPNYDEYQYNIAEIGHN
                     PYHLISYLTAKYGDWTYSDVENELQALFEAQYHLNTEGRTETVTETRNVRVGESLGQV
                     VTSGYCNCRICCGVWSGGPTASGAYPTANHTIAVDASNPFVPIGTKVVMNGVEYTVED
                     TGAFARYGVQFDVYYDNHAAASAHGHQTWEAYIADDNGSQEVTVTSTSTKKILYVTLT
                     NGSFDAVARANLNAEQLIIYNALNTTYGNRNYLWDVNNVTSGSGGNGMSYEIPPEALQ
                     DEEFARMIREAEKYLGVPYVWGGYSPSGFDCSGFVSYVLNHCGNGWNYGRLTAEGLRG
                     VCTYVSPGEAKPGDLIFFQGTYNTSGASHVGIYVGNNMMIHCGDPIHYSNISTSYWQQ
                     HFMCFGRLP"
     gene            85005..85313
                     /locus_tag="LP493_000205"
     CDS             85005..85313
                     /locus_tag="LP493_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005334805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HBL2132387.1"
                     /translation="MNKKIKKYLDEIAKTEKKIADLQQYLRGVQAALKQEEDNEMIRC
                     IRGMKMDNDQLYDLLDGIQSGKVKFQVSRESDDEGSGSFVFTEENKEEYQNGEMEENE
                     "
     gene            85288..86022
                     /locus_tag="LP493_000206"
     CDS             85288..86022
                     /locus_tag="LP493_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003864570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HBL2132388.1"
                     /translation="MVKWKKMNKKMAGLLLGVMMLFTASTTAFAYVDESAEASKVETT
                     QTEQSTDKEEKKDEATNTNEVLPEDGTDQGTAFTTPGNGEVKDDITDDSTKEFLTVTT
                     KNNNTFYIVIDRSATSQNVYMLSQIDENDLSEFLDKDSTAAVVTPQPDTSKVVLDETN
                     NEDVDKEATVDPEKTSSAKTNMGAMATILILALGGVAAYYYFKIYKPKKEEDEDDQPE
                     GLETGGLEEVPDEEESEDEDFEENEK"
     gene            86095..88206
                     /locus_tag="LP493_000207"
     CDS             86095..88206
                     /locus_tag="LP493_000207"
                     /inference="COORDINATES: protein motif:HMM:TIGR01056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HBL2132389.1"
                     /translation="MYLVIAEKPSVSRAIAEVIGAQEREDGYLQGTDCMVSWCFGHLA
                     EYVSPDAYDEKFNQWRYEDLPIIPKDWKVTVSEDKKDQFYILKRLLNSPEIEYVVNAC
                     DAGREGELIFKHVYDLSGSKKPVKRLWISSLEDSAILDGMQHLRSAEEYRHLAEAAVC
                     RSQADWLVGMNATRAYTTKYFKKLTVGRVQTPTLAMLVERAGQISNFQKEKYFNVELD
                     CDGIPAVKPKIFDPDEAEQLRSRCQGSEAIVTAVKETEKKVKAPKLYDLTTLQREANR
                     IYGMTAKQTLDTAQNLYEKKLITYPRTDSQYLTEDMEQTARNVVRQIYEKYQLTGPFD
                     QPEQPDVKKVMNNSKVTDHHAIIPTMELSSCHLDELKSWEEKILFLIAVHTVMAMSKE
                     HVYQETEIEVECQGEIFKAKGKTVLQDGWKLFENCFKNKDRMAIVDPDQEMKEKIPKV
                     TQGQTFYAVAAEKTEHFTSPPKPYSEDTLLAAMETAGNKEFDEDTEKKGLGTPATRAG
                     IIEKLIYSQYATRKGKQILPTEDGKVLVEILPDFLKSASMTAEWENQLLLMEHGEIAP
                     EQFMTGIKNMLTMMLNGCDAISEEETRRFQTRESIGTCPVCGSLVYESKPNFYCSNHD
                     CHFALWKDNRYLQSMEKTMDKKMAAELLKNGSVHVKDLYSRKKNMYFEADLHMDTDET
                     GKVNFSLSFPKKKSKNKSKKK"
     gene            88235..89284
                     /locus_tag="LP493_000208"
     CDS             88235..89284
                     /locus_tag="LP493_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005334802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132390.1"
                     /translation="MNFNEFVSEVKDNIKLFLPEEYENVEVSTMECQQLNRAYTGLMV
                     RKEGEMLTPTINLNQLYEAYKAQPGVTMETVCRKIADIVIEAPIQVDLKAIFNYEDVK
                     DKLFIRVSSAEANKEVLENAPHQLKEDLAITYHVAVDKDENGLSSMFIKNDLLEQYGI
                     SAEQLHEDAMKSSPRVMVPEVSSIGALIDEMYQKNILMLTPDEREMLQETLQESSEMP
                     TFFVVTNTERVDGAGVIFYPEFMDNMGELLGNDFFILPSSIHEMLILPDDGQVDAEML
                     RDMVKEVNATQVAPAERLTNDVYHFDTKDHVFEKADRFTERQKEKEAQAAKTEKAGKE
                     QPDQKPKTKKHDMEL"
     gene            89367..91388
                     /locus_tag="LP493_000209"
     CDS             89367..91388
                     /locus_tag="LP493_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015535387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1738 domain-containing protein"
                     /protein_id="HBL2132391.1"
                     /translation="MTEQNKTTTIPLPVPGKDMDSIMQSLESGVEELFTSNRYQEFLK
                     TMAKFHNYSFNNTMLIAMQRPDATLVTSYKNWQSMGRQVMKGEKGITIIAPAPYKKMK
                     EKEVLDENQRPIMGSDGKPKTEQVEVTVPHFKAVTVFDIAQTSGEPIQTLAPELLTAA
                     VQDFDSFMQAIQKISPVPIRFDEIDDNANGYYHNADKEIVIKKGLSESQTLKTAIHET
                     VHAKLHDREIMESLGVEKDRLTKEVEAESVAYCVCSSFGLDTSDYSFPYIAGWSSSRE
                     MKEMKASMDVIRKTAGEMIDQLTEELEIILEEKQKTELHDKYGILVDALEAAGYRYDY
                     RESEPGHIVLAPDGTHEIAGYLQFESWGDIKDWLEDTIAEGTDISERVDRALYPFKFD
                     YTLEEEMFRGNGDRYAIYHVDEDTPGKQHLFMNMAMVKEDGITIDAANYKCVYSGRLH
                     ENEKLDDLYAVFNDNPPADYKAHSMSVSDVIITNRGGDMQAYYVDRFGFAELPDFAVQ
                     REKILDIVPEIENVDYENDLTCISFYAAECAEFPVMGEVHYDLTLPEALEAYEKIPSE
                     RMHGLKCVGFDLKDGSDYEGMQSLMIEGKIQKEFLNSIPGFRENSYVQNAISRVEKYL
                     EERHPNVENPLESNKKVDNEKNISKEKNEKELNIQMKPIPKKKRGEMSL"
     gene            91385..91645
                     /locus_tag="LP493_000210"
     CDS             91385..91645
                     /locus_tag="LP493_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005423594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HBL2132392.1"
                     /translation="MRNVNLEENELTITAIFQQHTKEETIQTLKEALEVMEQEESDPE
                     NDEMIEIINSTVGKLQQIEDKYYYSLDLNYYLNNLENDAYEA"
     gene            91635..92519
                     /locus_tag="LP493_000211"
     CDS             91635..92519
                     /locus_tag="LP493_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4316 domain-containing protein"
                     /protein_id="HBL2132393.1"
                     /translation="MKLNQFAVYRVDQQTAGKALWHLPYQEARQQNVSITVENYRLVS
                     IHEMQENEKVADIWKRMKKQCEVSDVLVLNKNGEISCYYVDENYPQYLAGFIRINTSG
                     ALITMETENYQIDGKKGNWIATDTIIIDGKQFYLMEHQVYRDQAQGVILDAYGKMVVE
                     ECKKFDEKTKQKIHDYIQQQVPLNPVEQLKQDGKIRLEHYQKFYQNGTYERSRESGTE
                     ANYDMVDGLVNNQKKNQEKTSDASSNNQTSRNQQDGKSKKRRSVIKRLHQKQIAIARR
                     SGKPIPKYLDQEMERKRG"
     gene            92523..92813
                     /locus_tag="LP493_000212"
     CDS             92523..92813
                     /locus_tag="LP493_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015535390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HBL2132394.1"
                     /translation="MRRLKCEKETIILTNEDDGFYDVYTFNQSLQKRLRAFAEKYPDD
                     CWLKGSSEDGSETYIIKKGRLSLNLRPPYSKDRIHKATERIIEEQKEQSKDS"
     gene            93073..93270
                     /locus_tag="LP493_000213"
     CDS             93073..93270
                     /locus_tag="LP493_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014073062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132395.1"
                     /translation="MARPKKNGTYLNVCIETPIYERLENFCKDAGHTKTVAVERALIS
                     YFDEYEEMKKKLKELESNQDK"
     gene            93299..93490
                     /locus_tag="LP493_000214"
     CDS             93299..93490
                     /locus_tag="LP493_000214"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132396.1"
                     /translation="MINGKDQEIITINKTGNSILNNAKYSADNTDEWYTTFVARSFDF
                     GRKKRLQPPCAAISRFLIL"
     gene            complement(93493..93849)
                     /locus_tag="LP493_000215"
     CDS             complement(93493..93849)
                     /locus_tag="LP493_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2132397.1"
                     /translation="MAKRPVPLYDFKAFGAAIKAARNEYGESRKKVSDELYISPRYLA
                     NIENKGQQPSLQVFYDLVTRYHISVDQFFFPNSNAEKSTGRRQLDALLDGMSDKGIRI
                     VTATAREITEVEKAED"
     gene            94248..94433
                     /locus_tag="LP493_000216"
     CDS             94248..94433
                     /locus_tag="LP493_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL2132398.1"
                     /translation="MLKKYWIKCPICNGKTRVQVFHNTVLKDFPLFCPKCKLTHIIDV
                     EKLEIVIKNTEKQTFII"
     gene            94450..95433
                     /locus_tag="LP493_000217"
     CDS             94450..95433
                     /locus_tag="LP493_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004607971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBL2132399.1"
                     /translation="MKRLPKYTPAEVRNDPYGFTYKEMSEVIGENEAKALYEELYKQL
                     PRKKNLSMLVKNICKSSDTEKYVYELKDNKYIETVFIKRRDGGTVCVSTQVGCPVGCI
                     FCESGRNGFVRNLTSSEIVQQIILLRRKVNRIVFMGMGEPLFNYDNLIKAIHILRDRY
                     GLNFPTDGITISTVGPVDQLKKLREEHLKIQLTISLHAATQSARNRIIPHMRIYAIED
                     VVKQALSYSERHNRKIVFAYLLLPGINDRPSDVRQLAKWFRGKKVMINVLQYNPTSNS
                     RIKAPQKREIVAFKHQLEQAGLEVTMRVSHGREINAACGQLANTYNKFKKK"
     gene            complement(96078..96251)
                     /locus_tag="LP493_000218"
     CDS             complement(96078..96251)
                     /locus_tag="LP493_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002779755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HBL2132400.1"
                     /translation="MMKCEWILCPVCGSKTRNKIRKDTVLKNYPLYCPKCRQERLIKV
                     DNLKITVIKEPDA"
     gene            complement(96303..98222)
                     /gene="tet(O)"
                     /locus_tag="LP493_000219"
     CDS             complement(96303..98222)
                     /gene="tet(O)"
                     /locus_tag="LP493_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032490535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(O)"
                     /protein_id="HBL2132401.1"
                     /translation="MKIINLGILAHVDAGKTTLTESLLYTSGAIAEPGSVDKGTTRTD
                     TMNLERQRGITIQTAVTSFQWEDVKVNIIDTPGHMDFLAEVYRSLSVLDGAVLLVSAK
                     DGIQAQTRILFHALQTMKIPTIFFINKIDQEGIDLPMVYQEMKAKLSSEIIVKQKVGQ
                     HPHINVTDNDDMEQWDAVIMGNDELLEKYMSGKPFKMSELEQEENRRFQNGTLFPVYH
                     GSAKNNLGIRQLIEVIASKFYSSTPEGQSELCGQVFKIEYSEKRRRFVYVRIYSGTLH
                     LRDVIKISEKEKIKITEMCVPTNGELCSSDTACSGDIVILPNDVLQLNSILGNEMLLP
                     QRTFIENPLPMLQTTIAAKKSEQREILLGALTEISDGDPLLKYYVDTTTHEIILSFLG
                     KVQMEVICAILEEKYHVEAEIKEPTVIYMERPLRKAEYTIHIEVPPNPFWASVGLSIE
                     PLPIGSGVQYESRVSLGYLNQSFQNAVMEGVLYGCEQGLYGWKVTDCKICFEYGLYYS
                     PVSTPADFRLLSPIVLEQALKKAGTELLEPYLHFEIYAPQEYLSRAYHDAPRYCADIV
                     STQIKNDEVILKGEIPARCIQEYRNDLTYFTNGQGVCLTELKGYQPATGKLICQPRRP
                     NSRIDKVRHMFHKLA"
     gene            complement(98589..98963)
                     /locus_tag="LP493_000220"
     CDS             complement(98589..98963)
                     /locus_tag="LP493_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001129922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TnpV protein"
                     /protein_id="HBL2132402.1"
                     /translation="MVQSIFEEMGGRYERQGEYILPCLTIPPEKEQSIDLFGRRHLDY
                     LREYRKITYTNLLTSGRLNAYLADIDRQAQEHFERLIEGMKQAQGITECLKEENALEW
                     TGRTNNIRACAREIVEKEIIFA"
     gene            99287..99715
                     /locus_tag="LP493_000221"
     CDS             99287..99715
                     /locus_tag="LP493_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003864549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132403.1"
                     /translation="MKKNNITLVFVAIVFSIIVGMIIGKSLLKYKEGEPDVVGSFSMN
                     RDENFTVVANRKNISDKEAFARLLLKMYKENSFHSIKFSTDHGYATSLDMTVYSWKED
                     IENGESIMQIEFRPIEYGKDYDLVHNPDKYVLLIDGTEIK"
     gene            complement(99845..100123)
                     /locus_tag="LP493_000222"
     CDS             complement(99845..100123)
                     /locus_tag="LP493_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006426622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2132404.1"
                     /translation="MITFGRKLKHLRQKNHLTQKELGMAVGFPDSCADVRIAQYESDV
                     RTPKEDLMKLFASTLGVPVELFTVPVLSEPREYEAAEYWRYELGAELD"
     gene            complement(100128..100541)
                     /locus_tag="LP493_000223"
     CDS             complement(100128..100541)
                     /locus_tag="LP493_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008976873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyuridine 5'-triphosphate
                     nucleotidohydrolase"
                     /protein_id="HBL2132405.1"
                     /translation="MKIKLIDFGLKADHHPFRPHENDAGADVFMPYDCVLKPGEVARI
                     PLGFGLIIPDGFAGYVFPRSSMAAKGLVCELPPIDSGYRGEIHAIISNVSTSSQTIHK
                     DTRVGQLVITPVVIADFVLDLGEERGTGAFGSTGE"
     gene            complement(100531..101310)
                     /locus_tag="LP493_000224"
     CDS             complement(100531..101310)
                     /locus_tag="LP493_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009267089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent thymidylate synthase"
                     /protein_id="HBL2132406.1"
                     /translation="MDHIETAILNCYGIREAEQNMVFAARLTQHGHTIQNMADLMDLY
                     RQSYSQKTVENIAGLPHPTVQKFMVITVAVVGASRRFLAQITRHQNEVKYMSASLQYS
                     NYSGHAAFAIPYGIMKADKEIQDIYKKSCQSDLDHYAELCALGIDHDSAGYATPQGLR
                     NVLIISATPYQWKHMIGQRTCRRNTDETRIVMLYIWQRLYKLSPILFAPDLTGPFCQR
                     GSCMEKQMSCQNPISKLWMPADILKTDYPLLIRKEMSSHKD"
     gene            complement(101297..101623)
                     /locus_tag="LP493_000225"
     CDS             complement(101297..101623)
                     /locus_tag="LP493_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009263519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132407.1"
                     /translation="MTQEEFNIVFELQMRKCADILAHKKKEYTGDNIDRLSAFKIAAA
                     LQNCDPKAALAGMMSKHVVSLYDMCYSTLLHFDMEQWDEKITDCINYLILLKALVKEE
                     QAYGSH"
     gene            complement(101653..103206)
                     /locus_tag="LP493_000226"
     CDS             complement(101653..103206)
                     /locus_tag="LP493_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004606465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBL2132408.1"
                     /translation="MAIVKHIKSRNANYSAAINYLLFEHDEKTGKKIVDESGRSIMRK
                     EFYMDGLNCDPMSFDKECELTNAHFHKNKKRADIKSHHYIISYDPADVTENGLTGPIA
                     QAISLELAKQMFPGYQALVVTHTDGHNESGNIHTHIVINSVRKTAVERQPYMDKPHEE
                     AAGYKHRSTDKFMNAFKKTVMERCQQEGFHQIDLLVPAERKTTQKEYIAQKHGQQKLD
                     EINQKIIEDGLKPTSTVFLTQKEYLRNAIDECASTSNSFDEFQSKLLEQFQISVIEHR
                     GRYSYLHPDRQKRITERSLGTRYGKEHLKQTFLRKDPLAILYVRSHLRLVVNLQTNVK
                     AMQSPAYAHRVKLSNLQQMANTIIYVQEHGFDTQSDLKNTLVASKQELKEMQTQFAQH
                     RSDLRILNDQIRYTGQYYANKEVYSQFSKAKYKGKYRKEHAKEIQKYEEARNWLKSFY
                     QDGNMTSLKTLTLQKEKLQQQIASEEEAISSLKEKLKDLDTADQNVDAILQMQIPEPV
                     RSKNKDLER"
     gene            complement(103184..103570)
                     /gene="mobC"
                     /locus_tag="LP493_000227"
     CDS             complement(103184..103570)
                     /gene="mobC"
                     /locus_tag="LP493_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009263517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBL2132409.1"
                     /translation="MAPKKKEKNLKRSNIITLKLTDIELAVLNEAADVTGLSRSEYVR
                     KLLLEKQINHQIEVVADMNDLRKLVSEYGKIGSNLNQIAKHFNSGGSQSRAIENEIHQ
                     CITDLFLLRKEVLKLAGGMNGNRKTH"
     gene            103954..104379
                     /locus_tag="LP493_000228"
     CDS             103954..104379
                     /locus_tag="LP493_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003864588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2132410.1"
                     /translation="MIRKLLNGDIDRIADIWLKTNLKAHYFISNQYWKSNYELVKEMM
                     SQYEVYVFEADKMIQGFVGLNDKYIEGIFVSDEMQSCGIGKLLLDYVKDKKVSLRLNV
                     YQKNARAISFYQREGFIIQYEGLDETTGEKEYTMLWKRK"
     gene            104435..104758
                     /locus_tag="LP493_000229"
     CDS             104435..104758
                     /locus_tag="LP493_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004613237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS biosynthesis protein"
                     /protein_id="HBL2132411.1"
                     /translation="MKIEGNQKELDAMVEFHKGNRVEGLRLQEEFAAEFRKEYKDKDH
                     CPCLKACRYHGNCKECVAIHRAHQEHVPNCMRPLINKKLKLMSELTEHTLANEIEAPH
                     EILRK"
     gene            104889..105515
                     /locus_tag="LP493_000230"
     CDS             104889..105515
                     /locus_tag="LP493_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008789344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL2132412.1"
                     /translation="MFDKHKRESLLLRDLLKKLIIIVIGSIVAAYGITLALYAGFGGA
                     TLAVLWQGIAETFHLSIGMASFVVAVGMILFALIYDKSQIHIGTVLYQIVYSTCVDVF
                     ATCHVYSTYRWFNFFIMLLGVILFAVGTGLYASASLGRGSYEAVTFALAEKNNWQVKI
                     VRIALDILVVIIGVLLGGKFGICTIITVIISGPIIQFVNAKAKRILKI"
     gene            105586..106029
                     /locus_tag="LP493_000231"
     CDS             105586..106029
                     /locus_tag="LP493_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005719578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2132413.1"
                     /translation="MKIREVNKNKKQFISLLLLADEQESMVDRYLEKGTMYVLEDNDV
                     KAECVVTDEGNGILEIKNIAVDPENQGKGYGKALIDFLASKYADEYSVLQVGTGDSPL
                     TIPFYEKCGFVRSHKIPNFFTDNYDHTIYEGGVQLIDMVYLQRHI"
     gene            106296..106472
                     /locus_tag="LP493_000232"
     CDS             106296..106472
                     /locus_tag="LP493_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005426062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2132414.1"
                     /translation="MSEKRCYTVQELQEILGVSRPTIYNLLKKKEFRWIQLDGGKYRI
                     SKKSFDDWLDNLEQ"
     gene            106593..107582
                     /locus_tag="LP493_000233"
     CDS             106593..107582
                     /locus_tag="LP493_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005423640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2132415.1"
                     /translation="MATAIMKQKEVPEMDDVEEIISKISEDSPYKRRPTQKRTWMTVP
                     EMGKLLGLKKTDRYWLVHKNVFESKEIAGKIRINIASFEKWYANQIKYHKVTGEEPGK
                     ELKSWSYSVKEVADLLGVDEYLVYDLLKKNQMEAVIVDYWKRIPKESFQNWYKSQSRY
                     RTKEDRKKDALLEDATITMPEMAQLLGTTRSAVYTILDNPKYSHFFEFIVIAEKKRIT
                     KESFRKFLEGQDRYKLDPSNDYEELAQEQNIALANFRRKKLSQTGIRGSNGNIKYLTF
                     DEASYLAKVSRSMINKWADKGKFTVIKVGSRVRIRRDEFEDWMEQRDLERSMQ"
     gene            107584..108975
                     /locus_tag="LP493_000234"
     CDS             107584..108975
                     /locus_tag="LP493_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008816766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL2132416.1"
                     /translation="MASIRERNGKFNVIYSYTNEKGERKQKWETYETKAEAKRRKKEI
                     EYKKEMGSFVVRKCKTLDELITEYVALYGKENWALSTYEGNVSLINNYILPIIGDTKL
                     SEINTRFIERYYQSLLKRRAVINPLNKTSRNEFVSSSTVRDINKLLRNCFEQAVKWEL
                     MEKNPCTHATVPKHKSQKRDIWTADTLMYALSVCEDERLKLAINLSFSCSLRLGELLG
                     LTWDCVDISHEAIEENRAYVFINKESQRIRKESLNALDGKDVLLVFPTNHKKNSTVRI
                     LKTPKTESSVRKIFLPKSVANMLVDWKAEQDEMKEILGDEYMDYNLVMASTFGLPLGD
                     GAIRGPLKKLIEDYNLPPVVFHSFRHSSVTYKLKLNGGDIKAVQGDSGHAQVNMVTDV
                     YSHILDDDRRKNAELFEEAFYEKKNLDPQMHVQQENNNTTVADEVDPELLAKVLANPE
                     MRALLNSLAKTMK"
     gene            109137..109328
                     /locus_tag="LP493_000235"
                     /pseudo
     CDS             109137..109328
                     /locus_tag="LP493_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008791949.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein Fic"
     gene            complement(109825..110964)
                     /locus_tag="LP493_000236"
     CDS             complement(109825..110964)
                     /locus_tag="LP493_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL2132417.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(111078..111662)
                     /locus_tag="LP493_000237"
     CDS             complement(111078..111662)
                     /locus_tag="LP493_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HBL2132418.1"
                     /translation="MAKKVMGQDGKMYKVSKPFYKKVWFWVLAVILIIIIGSALNGGS
                     DSNKASDNGGEKVTKSSTSASSSKEEKSDTFYKIGDTVKVGDAEYTLNSVELTDERNQ
                     FEENQPAQVVKITYTVKNDGDSDIPVGTDVEVYGPDDKKSETYANENTMGSVAPGKQM
                     DVTAHFTLNQKGEIEIHFSPLVSFEKAAIFKATV"
     gene            complement(111745..112167)
                     /locus_tag="LP493_000238"
     CDS             complement(111745..112167)
                     /locus_tag="LP493_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBL2132419.1"
                     /translation="MYLKLKEMLSEYNLKLIYMEMEEPGFYYPKPRIVFLNEKLHEDS
                     SEAFHLAHELGHFIASHFEYSVLYDNSTTFHSKFETEADKIAIMILLNIFIENELTDE
                     SQFKLENFMEFYAINNKLRTECFNVCQSYFKKKYSYAQ"
     gene            complement(112185..112505)
                     /locus_tag="LP493_000239"
     CDS             complement(112185..112505)
                     /locus_tag="LP493_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2132420.1"
                     /translation="MNTYEIIKELAKEKGLSIRQLEMNFGYSNGYLGSWKRQTPNSIE
                     LARLADYFGVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            112805..112945
                     /locus_tag="LP493_000240"
     CDS             112805..112945
                     /locus_tag="LP493_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132421.1"
                     /translation="MEKTVSAKIEDLKLDILKQAKVAMEHAVDKEDSAMVAAIAEILA
                     HV"
     gene            113243..113500
                     /locus_tag="LP493_000241"
     CDS             113243..113500
                     /locus_tag="LP493_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="HBL2132422.1"
                     /translation="MNKEMSQTIKVQKMIDDLTHGIDSQADKIIKELQGQKVKDAKML
                     LKTINFEMNPTKRKLADVLEEKLASAINEQELLFETDTFNS"
     gene            complement(113471..113779)
                     /locus_tag="LP493_000242"
     CDS             complement(113471..113779)
                     /locus_tag="LP493_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132423.1"
                     /translation="MKPEFVITMLDGEKIKIFADTLVVGYDDASNIEEKDGMFYSSQI
                     YVNTLQGDIGVSTLATSRPLVGLIGFLSKATFFSLGDDIDSDETVIYKTSAVKSIGFK
                     "
     gene            113857..114603
                     /locus_tag="LP493_000243"
     CDS             113857..114603
                     /locus_tag="LP493_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HBL2132424.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVADVLGYSNPQKAIR
                     DHVDLEDKTQNDSFTVNGTAVVLINESGLYSLILKSKLPSAKKFKRWVTSEVLPTIRK
                     TGSYSNVPQSFAQALRLAADLEEKNQLLEQQIAEYEPKISYLDTILSSTDTVATSQIA
                     ADYGMSAIALNKLLNELGVQHKVSGQWILYRKHMNQGYTKSHTSEIPKADGGTKVVMN
                     TKWTQKGRVFIYNLLIAEGYYPQMDLEEIG"
     gene            114618..114821
                     /locus_tag="LP493_000244"
     CDS             114618..114821
                     /locus_tag="LP493_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2132425.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            114837..115175
                     /locus_tag="LP493_000245"
     CDS             114837..115175
                     /locus_tag="LP493_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HBL2132426.1"
                     /translation="MQYLEAKIPVPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            115162..115332
                     /locus_tag="LP493_000246"
     CDS             115162..115332
                     /locus_tag="LP493_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132427.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEYKTKKPVGRD"
     gene            complement(115430..116095)
                     /locus_tag="LP493_000247"
     CDS             complement(115430..116095)
                     /locus_tag="LP493_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132428.1"
                     /translation="MSLIDFIKQFDWNNIVKTIKDFILPITSLVFSTFAFYISYTDRK
                     NKKFNLKLDFFAECEEWLIDRESDSKPDVYHQNKFRIIDSVLLTNNSSLPVTIIEFSI
                     SGIPDHLNAFTMIGDNYSVTVKSMYDELPHGIRAYSGKSLKKGADLSKFPPLSLPITI
                     PPYESKITTLVFRYDESLVEKNITINVLTSRGTAKFNRFVSSSQISQLDTGYAPPQLD
                     EFD"
     gene            116150..116848
                     /locus_tag="LP493_000248"
     CDS             116150..116848
                     /locus_tag="LP493_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HBL2132429.1"
                     /translation="MQELVILKNKEAVTTSLQVADSFEKEHKNVLRDIEKLKEDVLNF
                     EQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNIKVMEVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDENE"
     gene            117026..117367
                     /locus_tag="LP493_000249"
     CDS             117026..117367
                     /locus_tag="LP493_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132430.1"
                     /translation="MEKELSTLDQYLTDPSWGKSNIKETNNRKIRRNLLTDEELACDQ
                     DDLGNFVSIWDHVYLIHLSRKSKKPEYIYVIEDGLIDALEEYDRDNLIDISYYGSGKK
                     YIAEMEAEFDE"
     gene            117360..118031
                     /locus_tag="LP493_000250"
     CDS             117360..118031
                     /locus_tag="LP493_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HBL2132431.1"
                     /translation="MSENKGTTTFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVTPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            118037..118723
                     /locus_tag="LP493_000251"
     CDS             118037..118723
                     /locus_tag="LP493_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132432.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDIGATINEEVNIERLKTMYDGYDGD
                     RIIEVRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGG"
     gene            118726..119475
                     /locus_tag="LP493_000252"
     CDS             118726..119475
                     /locus_tag="LP493_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2132433.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            119487..119756
                     /locus_tag="LP493_000253"
     CDS             119487..119756
                     /locus_tag="LP493_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132434.1"
                     /translation="MKIDYLELINEIAKYKTGEEIEILRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDTTQLRNLAYTKLLFVDCVKGLQKHLNELEQV"
     gene            119761..119925
                     /locus_tag="LP493_000254"
     CDS             119761..119925
                     /locus_tag="LP493_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132435.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            119918..120220
                     /locus_tag="LP493_000255"
     CDS             119918..120220
                     /locus_tag="LP493_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132436.1"
                     /translation="MDKKAAMQRIIELTYSEDWQNDKEAASEVMRLGRAMWADKSNKP
                     RPRKIAIWHGDKLLVIGTAEQLASLTGLHEKIVRKRARCGYTDAKKRTFRYVEESS"
     gene            120217..120378
                     /locus_tag="LP493_000256"
     CDS             120217..120378
                     /locus_tag="LP493_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBL2132437.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIHRLEE"
     gene            120375..120680
                     /locus_tag="LP493_000257"
     CDS             120375..120680
                     /locus_tag="LP493_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132438.1"
                     /translation="MSVDKKAAMKRIAELTKSESWQEDKEIVAEVQKLGKSMWTEKPK
                     RRTPRKIAIWHDDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEER"
BASE COUNT        40201 a        20712 c        26246 g        33585 t
ORIGIN      
        1 aatttaaacc ataattgtgt ttttccttcc attaacatat aaagttcacc tcaaaaagag
       61 tatacgaaca aatgtttgta ttgtaaatag aaaaagatga gctaaattaa atgcccatct
      121 tctttgatag atattataaa tctaataatt cttgtttctt tttattaaat tcttcttctg
      181 taatgattcc atcatccaat agttctttat attttcttat ttctgaagct gaggaaattg
      241 ttgatgtatt ggaatttgta gcagaaatat ttcttctttt taaattataa ataatttcgt
      301 ttaaagaatc acttatccta tcaacagtat ctttatcaac tgcaacattc aatactttac
      361 caagagtatc aatagttaat gtacccaaca gcactcctct ttttttacta atattattta
      421 aattgtctaa tataatactt tgtacattat tgcctatcat tttttgttga gctacaatta
      481 aacgtttatt agttaatgcg tatgcataat tattgtcatg cttagttgat gagatataat
      541 tatgcaatcc tacaaagcag aagattacgt attcgtcact gttaagttga tctgatatta
      601 agttaaaatg atgagttgtc cattttttag tcattccttt accgtagccg tatttaagac
      661 aaaattctac catctcttca gtggttctca ttctatcatt acctatatca tgattgtttt
      721 gtgcagtatg atcagatatg tttaattttc ttttttctga tggatcctta tctaaatctt
      781 ctaaattcaa agatcttatt attttataag gagtagtcat accgtaacca gcttttttca
      841 tacaattgcc gcaaacaatt tgtttatctt tgattttata tgaagttaag ccaattttac
      901 ctccgcactt tgcacattgt ttactcacat tagttcctcc tagatatcag ctttctacta
      961 ctattaacat tctatcaata gtgaccatac tttgaccata ctttttagaa agaatagaaa
     1021 attccaagat atttaataat agaagaaaag cactaacatc atgggttcag aagaattgag
     1081 agcttatcag gaaacagtat aattgaagtg tctgtttatc cagtagctca agaagcttaa
     1141 ttgaatctta tgattaaaga ggttgtgaca agacttttgt cacagccttt tttgtttata
     1201 aaaataaaag ttgtagtgga ggctacgaag tttactttgt ctttttacac ttaatatttt
     1261 tttgccaatt tggaatcagg atgttttgat aactatcgtt ttcaattgat ggaagctata
     1321 ttgtttgcta tcagtgaaat aattatatgg taaacagtgt tctttttctt gtttccatta
     1381 taaaaatcgt atcgggattt ttcgttcttt taaattgaac atttctatct atccgcgtgt
     1441 tatcaacaaa acaaaatcag gtaaatagtt gacgaaacag aaataaatac atagtattat
     1501 gttttgaagc ctaagtacaa tagtctatag aaaaggagcg ataccattgg caaaacgcat
     1561 tgaccgaatt tatatgtatg tcaaagaaaa aaccgctcat ttaacaaagg cagaatatga
     1621 tcaaggagta acaacacagg aaattgctga agtgttaggg attcagcgaa caaatagcag
     1681 taaagatctg aatcagctag tgcgcgaagg aaaactgata aagacagacg gacgaccagt
     1741 acgttacata tatcaaacac tcgttacgca cgtaaagcca gttacaaaac atgtagtcag
     1801 ttacaaagaa acgccggtct ctgaagaaaa aaatacactc caaatagata ctaaggatat
     1861 ctttgcaaaa atcattggag ctaacggcag catgaaaaat tcagtggaac aggcaaaagc
     1921 tgcgattttg tatccgccaa gaggattaaa ttgtttgatt acaggaccta ccggatcagg
     1981 aaagacttat tttgcacacg cgatgtatca ttttgcaaaa gcgcatcatg taatagatga
     2041 ggaaacggaa ctgattgttt tcaattgtgc tgattatgcc aataaccctg agcttttgat
     2101 gagtcattta tttgggtacg caaaaggtgc ttttacaggc gcagatgaag aaaaaatggg
     2161 gattatcgat caagcggatg gcggtatgct gtttttggat gagattcacc ggttgccgcc
     2221 tgaaggtcaa gaaatgatct tttactttat ggatcatgga acttacagtc gtcttgggga
     2281 aacaacgaaa tcccatgaag caaatgtacg gatcgtaggt gcgaccacag aagacccagg
     2341 ttcttctcta ttagaaactt ttgttcggcg tatcccaatc aatatcaaac ttccggcttt
     2401 tgaaaaacgt cctgcaaatg agaaagtcga tttagtaaaa atcatgattg cccacgaagc
     2461 aaaccgcacg cagcgaaaga tttctttgac agaagatgta gcaaaagcat tgatcggcag
     2521 tgtgacctat ggaaatatag gacaattgaa gtcaaatatc cagttagtat gtgcacgagg
     2581 atttctaaat catatgcaat cacccgaaat ctcgatcaca atcgatgatt tgacagaagg
     2641 gattcgtagc ggattgattc aattagcaag caaccgcagt gcaatggcag agctttctaa
     2701 aatattggag ccaaagataa ctgtagcacc aaatgatacg atcatgaaaa tccaatcgga
     2761 ctcctatgag ttaccttata atctatatga tatcatcgga gataaagcag ctttactgaa
     2821 gtcggatggt ttggatcaag aagcaatcaa tcatttcatt tctacagata tcaacatcca
     2881 tctgaagtct ttctataaag accatggttt ttcttttaat gcagacagca aattagcaga
     2941 atttgtagat ccgaaaatca tagaagtgac caatcagatt tatgtaatgg tcaaaagatc
     3001 tttaccatat gagtttcagc aaaactttat ttatgctatg agcttgcata tcagttcttt
     3061 tttgaaaaaa atcaacttag gagaagaacg gcatacgaat gataacatcc gtgagatggc
     3121 ttttgatttt ccagatgaat atgctgttgc gaaagaagtg cgtagttata tcgaaacgta
     3181 ttttcaagtg gagattccag aaagtgaaga ctattacttg accgttctac tcgtctcgtt
     3241 acgggcaaat caagcaagcg gcagaatcgg tgtagtcgtt gcagctcacg gaaacagcac
     3301 agcaagcagt atggtccaag ttgtccaaca gttgttagat gcagagaacg tacgagcagt
     3361 agacatgcct ttggatatgg atccgaaaac agcattggac cgaattgaac gcaatgtaca
     3421 agaagtagat gaaggaagcg gggtcatact cttagtagat atggggtccc ttgcgtcgtt
     3481 taattcgcaa attcaaagag acactggaat tccagtacgt actgttgata tggtaacaac
     3541 ttctctagtt ttggaaactg tacgaaaggt ctcagtatta gggacagatc tagatatgtt
     3601 gcatgaatca ttgaaaaatt ttcgaggtta cgcagaaata tcttctgtag aatctgttca
     3661 ggaagcaaaa cctattcata agaaaaaagc tgttttggct atctgcgcat ctggcgaagg
     3721 tacagcacaa agaatcaaag aattgatcga acgagcggta aacaagcgtc aagaaacaga
     3781 attagaagtt ctagctttgt cgattgtgga agtgaaagaa gaactgccag ttatccaaaa
     3841 agaatatcag atcatagcta ctactgggat tactgatttg aatatccaag ccccatttat
     3901 tcctttagaa cgttttattg atcaaaatat cgaagtcatt ttggatcagt tgctgatgga
     3961 atcagaattg gaggaaactg aattcatctc cctagatgaa gagtcagcta aaaatacgtg
     4021 tgttgagttt atctctgata acttcatctt tattaatggt agtaagttaa tcgatccaat
     4081 gtggcaattt tctacacaaa tctctcagac gacgggaatc ggcgatgaag aatatggatt
     4141 caaaatcaac ctagtgatgc acacagcagg aatgatcgaa cgtattattc ggaatgaacc
     4201 attgactgtg gaagaaaacg aattgacaaa tacaacgaat gatcctcttt atagccaatt
     4261 ggcagcctca gttgttctgt tggaagatca gataaaagta aaagtgccga tagaagaaat
     4321 gtattatctg ctacgtctag tccataatca gttagataaa aaagaataca ctgtgccatg
     4381 aatacacaaa aacgatacac ttttatagtg tatcgttttt gtgtattggt taagaatcct
     4441 ttaaattcaa ttagtgtatc gtaaaaaagt tggcacgctt tttgcttata gtagtgtgtg
     4501 ctaggaggtg gttgttcaca cagaaatgat aggggtttct gtgaagtagt gaggaagaag
     4561 gagttttgca gatggatatt cgattggcac gtatagatga tcgtttaatc cacgggcaag
     4621 tcgcaacagt ttggtcgaag caaacaggtg ttgaacgtat cattgtgatc agcgatgtag
     4681 tcgctcaaga taaattgaga aagtttctac taaaagaagc tgcaccgccg gggatcacag
     4741 caaatgtaat aaccgtgcag aaaatgattc aaatctatca tagtggatta ttatcacgag
     4801 caaaagtgat gcttttattc accaatcccc aagatgttga agcggttgtc cgctgcggtg
     4861 tacagttgaa gtcgttgaat atcggcggta tgagttttac tgaaggcaaa tcaatgatta
     4921 ccaattttgt ttcagtaaat caacaagata ttgattcctt tcgttacttg aacagtcaag
     4981 aagtggagtt agagattcga aaagtacctg ctgacaggaa aatccttttg atggaactac
     5041 tagcgaaaat caaaaaggtg tagcaagaat ggttgttgga aaaggtcaaa taattctgtt
     5101 gtaatggtta gcaattatta atatttttga atttgttaca acaaaagtaa ataggaggta
     5161 taaatatggt agggattatc ctagcaagtc atggacaatt tgctgaagga atcttacaat
     5221 ccggttcaat gatctttggc gaacaagaaa acgtcaaagc cgtgattttg aaaccaagtg
     5281 aaggtccaga tgacttgaga gccaaattgg aagaagcggt tgcttctttt gataatcaag
     5341 acgaagtgtt attcttagtt gatttatggg gcggaacacc gttcaatcaa tcaaacacat
     5401 tattcgaaga gcacaaagat aaatgggcaa tcgtcagcgg tttgaattta ccaatgttga
     5461 ttgaagccta cgcatcacgc ttttcaatgg aatctgctca tgaaattgca gcacacatca
     5521 ttgaaacagc aaaagacggt gtaaaagtaa aaccggaaga attagaaccg gcagaagcac
     5581 cgaaagcagc agttgaagac gcacaaccta aaggagcact tccagaagga actgtggtcg
     5641 gagacggaaa aatcaaatat gtattagcac gtgttgactc acgtctgtta catggacaag
     5701 ttgcgacagc ttggacaaaa gcagtgcaac caaaccgtat tatcgttgtt tcagatgcag
     5761 tatcaaagga tgatctgcgt aagagactaa tcgaacaagc tgctcctcca ggtgtaaaag
     5821 caaatgttat tcctattagc aaaatgatcg aagtagcaaa agaccctcgt tttggaaata
     5881 ccaaagcatt gcttttattt gaaaatcctg aagacgtatt gacagctgtt gaaggtggcg
     5941 tagacatcaa agaattaaat gttgggtcaa tggcgcattc gatcggtaaa gtcgttgtaa
     6001 gtaaagtatt gtctatggga caagaagacg ttgaagcgtt tgagaagctt gaacaaaaag
     6061 gtgtgaaatt cgatgtacgt aaagtaccta atgattcacg cgataacatg gatgatattt
     6121 tgaaaaaagc aaaagctgaa ttagcaaaag cgtaataaat aatattaaaa tttataggag
     6181 gcttatcatg tctattattt caataatttt agtcgtatta gttgcctttc tagctggtat
     6241 ggaaggtatt cttgatgaat ttcaatttca tcaaccacta gtggcatgta cattgatcgg
     6301 tttagttacc ggtaacctcg aagctggtat cgtacttggc ggtacgcttc agatgatcgc
     6361 tttaggttgg gcaaatatcg gtgccgctgt agcaccagat gctgcattag catcagtagc
     6421 atcagcaatt attttagttt taggtggaca aggtgttaaa ggtgttcctt ctgcgatcgc
     6481 gattgccgtt cctttggctg ttgcagggtt gttcttaaca atgatcgtac gtacaatcgc
     6541 tgttccaatc gttcatttga tggatgcggc tgctgaagaa ggaaacatcc gtaaggttga
     6601 aatgtggcac atcattgctg tatgtttaca aggggttcgt atcgcggtcc cagcagcagc
     6661 gttgctattt atcccagcac aaactgtgca atcattcctt gaatcaatgc cagcatggtt
     6721 aacagatggt atggctatcg gtgggggaat ggtcgtagct gtaggttacg ctttggtaat
     6781 caacatgatg gctacaaaag aagtatggcc attcttcgtt attggtttcg ttgtagctgc
     6841 aatttctcaa ttaacattga ttgctctagg tgctttaggt gttgcattag ctcttattta
     6901 cttgaacctt tctaaaatgg gtggttcatc aaataatgga ggcggaagca actctggtga
     6961 ccctttaggc gacattttga atgactatta atcttgaagg aggaaaataa aatggcagaa
     7021 gaaaaaatca aattatcaaa aaaagatcgt ttagctgttg cgtggcgctc taccttcatt
     7081 caaggttcat ggaactacga acgtatgcaa aacggtggct gggcattttc tatgattcca
     7141 gcaatcaaaa aattatacaa aacaaaagaa gaacgttctg cagcattaaa acgtcacttg
     7201 gaattcttta atacacaccc atacattgct tctccaattt taggggttac attggctctg
     7261 gaagaagaac gtgcgaatgg cgcgcctgtt gatgatgtag cgattcaagg ggttaaagta
     7321 ggtatgatgg gtcctttagc tggtgttggt gacccagtgt tctggtttac agtacgtcca
     7381 atgctaggtg cactaggtgc ttcattagct atgggaggaa atatccttgg accaatcatc
     7441 ttcttcttag gttggaacat tattcgttgg gcattcatgt ggtatacaca agaatttggc
     7501 tacaaagctg gttctaaaat tactgatgac ctttctggcg gattgttaca agacgtaaca
     7561 aaaggtgctt caattttagg gatgttcgta ttagctgccc ttgtagaaag atgggtatca
     7621 atcaaattct taccagttgt atcaactgta aaattagata aaggtgctta catcgaatgg
     7681 gataaattgc cttcaggtgg tgaaggaatc aagagtgcat ttgaacaagt taataatggc
     7741 ttagcccttt ctcctgaaaa ggtaacaaca ttacaagaca acttagacca attgattcct
     7801 ggtttagctg cattaggatt aacattgtta tgtatgtggt tgcttaagaa aaaggtttct
     7861 ccaatcgtta tcatccttgg tttattcgta gtcggtgttg ttggacacgt catcggactt
     7921 ttataatcca taaaaatata gctcgggcgt tgtcccgagc tttttttata tagtatactg
     7981 ttcataaaca aatatctgga gggagaaaat ggttcaatca atcaatacaa aagtagactt
     8041 ggtaattgat gctacttcgt ttacgggtct gacagattac gggcaaatca tgataggtga
     8101 taatggtttt gagttttacc atgcgcgaga tagacgcaaa tatatccaaa ttccatggga
     8161 agaagtggat tatgtactag catcagtcat gctaaaggga aaatggattc ctcgatatgc
     8221 cattcaaacg aaaaaaaatg gtacatacac attttcttcc aaagaaccta aaaaagtgct
     8281 tcgtgcgatc agagaatatg tagatgaaga tagaatggta caatcattga gtttctttga
     8341 tgtagtgaaa cgtggtattc gtagtatgtt taaacgcaag taaaaaataa agaaaacttc
     8401 taagaggagg ttttctttat ttttttactt tgcagaagaa aatatgaaat agcaaaacca
     8461 attatttgtc ccctttaaat cccatatgct aaaattgatt agcaaagaag gaggttatat
     8521 tatgagttgg ttatggacat tgattgttgg agccgtgatc ggagcaattg caggtgcgat
     8581 caccagtaaa ggaaattcga tgggctgtgt aacgaatatc attgctggac tagtcggttc
     8641 aagtattgga caagcgattt tcggcgaatg gggaccaaaa gctgcaggta tggcacttat
     8701 tccatctatt ttaggcgcag tgattttggt agcagttgtc tcatttttct ttggaaaacg
     8761 atcataagtt tttacaaaat agtaaactaa aaggagttgc agcgagactg tgactccttt
     8821 ttggctttat ttatttaaaa taaaaagaag ttttccggaa atttttattt aactgtcgtg
     8881 tacgaagaaa agtttgctat aatggaaaaa agcgtgcaaa gaaagaggga gtttcattat
     8941 gatgctacgt gtagaaaaat tgcgcaaaaa aatgcaagaa gaaaatttgg attcattttt
     9001 ggttaccagt ccgtacaatc ttcgttactt aacgaacttt acaggtacga caggattagc
     9061 tgttattact ttggaaaaag cattttttat tactgatttt cgttataccg agcaggcggc
     9121 agcgcaggct caagggtttg aaattattaa aaatgtcgga cctatttttg atgaggtagc
     9181 aaacttagta cgcaaagaag aactgcactc attagctttt gaggaaacaa cagtctcatt
     9241 tttagaatat tcggttttag aagaaatcat cgatgcggaa ttagtacctg tttcacagat
     9301 gatcgaagaa ctcagagaag tgaaagatga agaagaaatc gctattatcg aaaaagcatg
     9361 tcatattgcg gatatggcat atgatcacat cctgaaaatg atccaaccgg gcatgactga
     9421 gattgaagtc gcaaatcaac tagactttta tatgcgttct cttggcgctt caggtgtttc
     9481 ttttgatacg atcgttgcta gcggattgcg ttcggctatg ccgcatggtg tagcaagcaa
     9541 aaaaatcatc gaacaaggtg acttgatcac attggacttt ggttgctatt acgaagggta
     9601 cgtttccgat atgacacgta cattcgctat tggtgatcct ggggaaaaat taaaagaaat
     9661 ttatcaaata gtcttagatg ctcaattagc agttattgat gctgcaaaac caggaatgac
     9721 tggtgtccaa ttagatgcag ttgctagaga ttatatttca aaacatggtt acggggaagc
     9781 atttggacat tctacaggac atgggatcgg tttagagatc cacgaaggac caaacgtttc
     9841 ttctcgtgca gaaaagcaat ttgtaccagg aaatgtgatc actgatgaac cagggatcta
     9901 cttaccagga atcggtggag tacgtattga ggatgacttg ttgatcacag aagatggaaa
     9961 tcgtgtgttg actcgttcac caaaagaatt gatcatctta tagtttcatc aatagaagaa
    10021 gtaagcgtaa aaatcagtgt tcacagactt tgttatagaa aatcactcga tttaatgata
    10081 cactatagaa gaacttttaa gctgtaagag ataataaagt tgggtgtttt ctccaattca
    10141 tagcagtttg cagctgatcg gcggcagttt tcttaccacg tgatcactat gccgcatcat
    10201 agagaattcg gatgtatctc gtgcttaggc aaagggagga ataaataaat ggcagatgaa
    10261 aaaaatttga ttttaaacgc aaaccaagat ttaggagaga tcgtgatcgc tcctgaagtc
    10321 atcgaagtaa ttatcgggat tgcagcttct aaagtagaag gcgtatacgg aatgcgcgga
    10381 acttttgcca gcaatgtcac tgaattatta ggacgtgcag ctcacggaaa aggtgtttac
    10441 ttagcaaacg aggaagatgg cttgaaagta gatctttact gttatctaga atatggtgtt
    10501 tcagttccta aagtagcaat ggaaatgcag gaacgggtca gccagcaagt ccttttcatg
    10561 acggatatcg atttatctga agtcaatatc catgtagtag ctgttgttcc tgaaaaatta
    10621 gaacaaccaa caatcgaaga actttttgaa gacgaagagg aagagaatga ataaagaatt
    10681 atcaagacac gagattcggg aaatggcatt gcaggcttta tttccattag acttcaatgc
    10741 agacctaaca aaagaagatg cgattttcaa cgcaatcgaa ttagaccacc gcgacatgat
    10801 caacgaagat gaatcagagt ttgttcctgt ttatcttgat acgctagttg gcggtgtctg
    10861 tgcaaaaaaa gatgaattgg ataaagtgat tgaaaaacat ttaaaaaaca attggcacat
    10921 caatcggatc tcaaaaatgg atttggtgat cttgcgtatc gcgatttttg aaatgactta
    10981 tgtgacagat gtaccagcgg ctgttgcttt aaatgaagca atcgagttgg caaaaacatt
    11041 tagtgatgac cgttcacgta aattcgtcaa cggtgtttta tccaatgtat tgaaagaatt
    11101 agaagctggg gcgtaagtcc tagctttttt ctatgaatca tcataaacct gttataaatc
    11161 gggaaaattc tatggtagaa tgaaaacaca aaaaatatct gggagtggtt agatggcaga
    11221 attgattaac ggaaaagaat tagctgaaaa aatgcaggca gagattgctg aaaaaatcca
    11281 aaaattgaaa gataatggta tccatcccgg attagtcgtt ttattggtag gggaaaatcc
    11341 agccagccaa atctatgtaa gaaataaaga acgtgtagca aaagaaatcg gaatccattc
    11401 attggtagag cgttatcctg agacgatttc tgaagacgaa ctacttgcag aaattgaaaa
    11461 atacaatcaa gatcctagtt ttcatggtat attggtccaa ttaccattgc caaagcatat
    11521 agatgaagaa aagatcctgt tagctatccg ccctgaaaaa gacgtagacg gttttcatcc
    11581 gatgaattta ggcagactcc ttgcgggtaa accggacaag attccttgta ctccatacgg
    11641 catcatgaaa atgtttgaag cttattctat cgatccggcg ggtaaacgag cagtagttat
    11701 cggacgaagc aatatcgtcg gtaaaccgat ggctcagcta ctcttgatgg cagatgcaac
    11761 tgttactgtt gctcattcta aaaccgaaaa tctggctgaa ctggcacaag aagcagatat
    11821 tttagtcgta gcaataggac gtggacattt tgtcacaaaa gaattcgtaa aaccaggtgc
    11881 tgtagtgata gatgtaggga tgaatcgtga tgctaacggt aagctgatcg gtgatgtgaa
    11941 atttgatgaa gtggagccta ttgcaggctg gatcactcct gtgccaaagg gtgtagggcc
    12001 aatgactatc acgatgctga tgtatcaaac cgtaaaatct gccgaagctt ttggagcagg
    12061 tgaatagatg gcacaagaat atttaactgt cactacatta acgaagtatt tgaaaagaaa
    12121 atttgatgcc gatccttatt tagaacgcgt atatttaaca ggcgaaatat cgaatttccg
    12181 tttacgtgcc aatgcccatc aatatttcag cttaaaagat gaccatgcaa aaatatctgc
    12241 tattatgttc aaaggagcat tccaaaaatt acgattccag ccaaaagaag gaatgaaagt
    12301 ccttgtcgtt gggcgtattt cattatatga agcgggaggt tcttatcaaa tctatgtaga
    12361 gcacatggag cctgatggaa taggtgcttt atatcaagaa ttggaagaac gaaaagaaaa
    12421 gctgatgaag gaaggccttt ttcaagggcc taaaaaaatg ctgccacgtt tcccaaagcg
    12481 aatcgcggtc cttaccagtc caagcggagc ggttatccgc gatatcatca cgacggtgaa
    12541 aagaagatat ccaattgtcc aattggtttt gttcccaaca gttgtacaag gaaaccaagc
    12601 agcggacaat gttgtcagga atatccagag agtagaagag atgggcaatt tcgatacaat
    12661 gatcatcggt cgtgggggtg gttcgattga ggatttatgg ccgtttaatg aagagcgggt
    12721 tgctcgggcg atttatcaag ctaatacgcc ggtgatttca tctgtaggac atgaaacaga
    12781 taccacgatc gctgatttag tagcagatgt tcgggctgcc actccaacag cagctgcaga
    12841 attagctgtt cctgttttgt cagaagagtt gatgcgcatt caagaacggc aagctagatt
    12901 gcagcaggcg tttgtacgcc agatccagcg caaacaagaa cggttcgagc gtgctcgacg
    12961 ttcctatgta tttcggcagc ctgaaagatt gtatgaaggt cagaccatca aattagacca
    13021 gttgaaacag cgattatatc aagctacaca gcaaatttat catgcgaaag aaaaacaaac
    13081 gatcgcatta agccaccaat tggaacaagt ggctccgctt tatcgagtta aagcagctcg
    13141 ccaagaaact gcttatctag aaaaacgctt agaagagaaa atccaacaat atatgaaaca
    13201 acagcagcag cgttttgctc aagctgttca atctcttgat ttgttgagtc cattgaaaat
    13261 catgggaaga ggctacagct atacgacgtt aaatgatcaa gtagtaaaaa gtgtcaccga
    13321 gattcatcaa ggggatttgc tgacgatcca ttatcaagat ggaatcgtta aaggacaagt
    13381 acaagagata gacaaaggag aataaaaata tggaaaatcc aacttttgaa gagtcactgc
    13441 aagaattaga aaaaattgtc atgcagttag aacaaggaga cgttccatta gaatcagctc
    13501 tagattcgtt taaacgagga atggaattaa gcaaacattg ccaagataca ttagctaaag
    13561 cagaagagac cttgacgaaa atgatgacag aatcaaatga agaagttgat tttgacggaa
    13621 acgaggaaag ctgagatgag attaactgac ttttcagcta ttcatctacc tgctgtagaa
    13681 aaagaaatct tgtctttttt agatgagcat acaacggata gaggactcta tgatgcgatg
    13741 agttattcag tgaaagcagg cgggaaaaga atacgtccct tattactttt aacggccgtt
    13801 gcttcctttg atgagcctat tgatgttccc gtctatcaag tagcagctgc tttagaaatg
    13861 gtgcatacgt attccttgat ccacgatgat ttgcctgcga tggacaatga tgatcttcgt
    13921 agaggaaaac ctaccaatca taaagtattc ggcgaagcat tagctatatt ggccggagat
    13981 ggtttgctta caggagcatt ccagctaatc agtatggcac acttaggtaa ttctcctaag
    14041 cttctgctgc ttcagcaatt agctgtttgt gcgggatcac aaggtatggt tgctgggcaa
    14101 gctgcagata tcgagggcga atcgaaaaag ctttctttag aagaattagc atttattcat
    14161 gaaagaaaga cagggcattt gattcgttat gccttgctgg ctggtggcat attagcgaag
    14221 caacctgaag aaatcttatt gctacttcaa cgattagccg aacatttagg tttagctttt
    14281 cagataagag atgatctact cgatgtgatt ggtacaacga aaacattagg gaaaacagct
    14341 ggtaaagatg aacgtatgga aaaaaatact tacccgcgtt tattaggcct agaaaagaca
    14401 cgtgaggcgt tggagattga gctgttatcc gccaacaaga tcatagacaa attagaagag
    14461 gacgtttttt cttttgatgg cgggctgatg cgccagatga tcaagcaatt tgatgtggag
    14521 aaatgaggga aagaatggaa aaagaacgcg tagatgtatt agcggtcaaa caaggattat
    14581 ttgaaacaag agaacaagcc aaacgttcag tgatggctgg tttgatttac aacgaaaaaa
    14641 acgagcggtt tgataaaccg ggagaaaaaa ttccagtgag tagtgaatta agagtcaaag
    14701 gtaaaaaact tccttatgtt tctcgagggg gattaaaatt agaaaaagca ctcaaagcat
    14761 ttgatctatc tgttgaagga aaaacattgt tagatattgg tgcatccact ggcggattta
    14821 ctgatgcagc tttgcaaaat ggcgcaaaaa tgagttatgc tttagacgtt ggctacaatc
    14881 agctagcttg gaaaataaga caagatccta gagtcgtcgt aatggaaaga gtgaattttc
    14941 gttatgcaaa acccgaagac tttaccttag gaattccaga agttgctgtt atcgatgttt
    15001 cttttatttc actaaaactg atgctgcctc cattacatgc tattttaaaa gaagagggag
    15061 aagtgattgc tttaatcaaa ccccaattcg aagcaggcag agaagctgta gggaaaaacg
    15121 gaattgttcg tgaccctcag acccatcaaa aagttttaga agacattttg tcatttgcgg
    15181 cacaaggtgg atatgatgtg ctggaattaa gttattctcc gatcacgggg ggagaaggaa
    15241 atatcgagtt cttggctcac ttgaggaaag tacccgaaag cggaacaatc aattcagcta
    15301 ttaatatggc agaagtggtt tcaaatgcac acgaacagtt tgaccataaa taaattgtaa
    15361 ctgtgaaaat caagtgagaa gtatgcggat tcttctttat tataccaagg aaataagcta
    15421 tcattgatta agaagaatat gctaaggagc gaagacgtaa tgagaaaaaa agatcggcat
    15481 cgtttgatta ctcgattgtt gagtgagcaa gatatccgaa agcaggaaga atttgttgaa
    15541 atcctgaaaa gcaaaggaat atctgttact caagctacga tttccagaga tataaaggaa
    15601 ctgaaactga tcaaggtacc ggcttcagat ggcggctacc gttatagcat accagctgaa
    15661 acaaacgaag atgtaaatac taaattggaa aaactattaa aagacgcttt cgtggcagtt
    15721 gaccaaatgg aaaaatttgt tattttgaaa acattgccgg gaaatgcttc ggcagcagca
    15781 aatttgattg ataaacgtta caagaaagaa ttattttcga ttatcaatga tgacgataat
    15841 gttttgatga ttacacgaac tgaagaccag gcagttttat tgaagaaaga cttcctgcat
    15901 tacctttaag ttgaggagcg aatgtgatgc tacaagaaat cagtattact aactttgcga
    15961 ttattccgga attgcggctt tcttttcacg aaggaatgac cgcgctgacc ggagagactg
    16021 gtgcgggtaa atccattatt atcgatgctt taggtctgtt agcaggagga agaggttcaa
    16081 gcgattatat acgtcaagga gcagaaaaat gtgtgcttga agggttgttt gaactaccaa
    16141 aacaagaagg attctctgaa ctgatggttg aattagggat cgaaacagat gaggacaatc
    16201 tgattgttcg acgggatatg tccttaactg gaaaaaatgt ttgtcgagtg aatggtcata
    16261 ttatcacatt agctaatctg agaagaatcg gcagttattt agtagatatc caaggacaaa
    16321 acgaacatca ggaactgctc cagcctgaat cacatcttgc tttattggat cgttttggag
    16381 atgtagcttt ccaacagaag aaaaagagtt atcagcaaga atatatctct tatcgtgagc
    16441 tggaaaaaag ggtacgaaaa gtgcagcaaa atgaaaaatc ctatgttcag agaatagata
    16501 tgctccattt ccagcaagaa gaaatagctg ctgctgattt gcaagtcgga gaagaagaga
    16561 aattaaaaga agaaagagaa aaacttagca attatcaaaa aattgctgat ggattagctg
    16621 caggttacgg agcactgacg aataatgaac aaaacagtgt agatggtgtt ggcttggccg
    16681 tttcagaact gcaagggatc gcccatctag atgtggagta tgaagcaatt tatgaaaata
    16741 tccaaagtgc ttactatttg ctgcaagatg caatcggcga tatgagtcgt cagattgatt
    16801 tattggagtt agatgagagt cgtttagaag aagttacgca acgtttagaa ttaatccgac
    16861 agttgaaacg taaatacggc gaatccattg agtcaatatt ggcttactat gacgaaatca
    16921 ccgaagagct agcttcttct gatttttcag aaggtcaatt ggacaaaatg aaagaggaac
    16981 tagagcaaaa agagcttcta cttcagcaac aagccgcaga tcttcatgaa gcgcgtaaaa
    17041 aaatcgcaaa agaattggaa aaatccattc tgcatgaatt gaaaagtctg tatatggaaa
    17101 acactgagtt tgaggtacgt ttcttaaaag aagaaaatag acaattgaat catgatggat
    17161 ttgaccaaat cgaattttac attacgacca atccaggaga gccactgaag cctttggtga
    17221 aagtcgcttc tggtggcgaa ctgtctcgga tgttgcttgc tttgaaaact attttttctt
    17281 ctgagcaagg tgtgacaagt attatttttg atgaagtgga tacaggtgtg agcggaagag
    17341 ttgcacaggc catcgcagat aaaatttctc aaatatcgaa atactctcaa gttttgtgca
    17401 tcactcatct gcctcaagtt gctgcagtcg ccgactatca atattatatt gtgaaagcag
    17461 tgattgatgg acgtacgcaa acttctgttt cagagttgaa aacaaaagaa agagaagaag
    17521 aaattgcacg tatgctggct ggaagtgaga ttacaaaact cacactcgaa catgcaaaag
    17581 aactattgaa actcgcaaaa aggacctgag ccacctcgca gtggttcagg tccttttcag
    17641 cagctgatag ctatatttta tttttacatg acactcatta cagcagtcaa tacaacagat
    17701 ccaatcgtta aaatcagcat tgtccaaatg acaaattttg ttactttagc aaaagtactt
    17761 gtttgttttt tttcacgcat tgttttcaac ctcgtcatta attagttgat tcaagtgtac
    17821 aatctttttt ccatttccac aagagggctt ttttataaaa acttcccttt ttttaaataa
    17881 taggtagtta cgatacaaat aaataatgtt aatagaacta gccatataaa ggcatcatcc
    17941 ctttcagcaa taggtaactt aatgttcatt ccatagatac tgccgacgat tgtcggtata
    18001 gttaaaataa tcgttaaaga agttaaaatt ttcataatat tattcagatt attcgatacg
    18061 attgctgaaa aagtctgatt catttgttct actagtttta attgaatgcg agaagtagtc
    18121 attgcctgct ctgtttccac caatacatca cgtaaatgat ttttcaaagc atgattttct
    18181 tggaaaagtt tattttgcgc tagttctttc aatgcatcta aattagcaga agtcgcttct
    18241 ctgaaataaa cgaggctttt ttggatatcc atgatttgat aaagttgttt gttttcagtg
    18301 gatacttgaa gtttggcttc caaagtatcg cattgagatt gaagcgtagc taaataactg
    18361 ttgtaagaga gtgtgacctg ccaaatgaat tgaaagaaga tattgagatt aggcgaaata
    18421 tcactttttg gaaaggtctg gctaaagact ttctttaaaa acagtggttc atgattcgta
    18481 attgtgataa gcttcttttt gggcgtcaaa ataatagaga gcgggtatgt atccacttga
    18541 aaataaccgc taggacttgt tttagcaaaa ggatattgta acaataataa cgctggcttt
    18601 gtcaactttg attgattgaa ttcttctgta cgggaatttt ctgcatcgtc caatatggaa
    18661 gtgatgtaat ctgacggaat ttcaaattga tgtgtcagct gatgaatctc ttcttgatta
    18721 ggacgttcta cacaatacca gatcgtttgg tcagtttcct ttccggtatt acgcagtttc
    18781 tcattatcta atgtaaaata tttgatcatg attttcctcc tgttgcctgt ttcttttatt
    18841 ataacggata gggaattgga atacatggaa tgtgtttgta agatatagaa tataactgca
    18901 taaatttaaa taaaatgaaa cagttgtgta aagtatatac agtatacttg aagcaacgat
    18961 aaaaaaggag tttacgttca tgggcacatt cacaccactt atcttgtttt ggtatattta
    19021 cccggtaatc gttttgtttg gttgccaatt tcttgtaaaa ttattttcgt taaatcgtcg
    19081 ttttaaaata aaagcccctg atttggcgat tccttttttg tggggcggta tgcatgcatt
    19141 gtctagaaat acagggacaa tttctatctt accgtttttc tttatttctg ttttgctaat
    19201 gggaatttgt attgctgttt tccaagcata ttattatgaa gaaattattt atccgcgtta
    19261 tttcaagatg acttggcgtt tggtttttct gttgacaatc gtcttgtacg ctgtcttgat
    19321 cattgtgaac atactttctt acctatgaaa aaaatagaaa agctgtaaaa agtcttttaa
    19381 aaggcttttt gcagcttgat ttttaaaaaa atgtttatga ataaaaaaag ttgttcccgg
    19441 atttcccaga aaaggtggta gaaagtgggg gattgtggta gactaatttt agttagtgga
    19501 ggaatggggg gctttcaatg ttgatgggtg aattccaaca taatattgat gcaaaaggac
    19561 gtttaatcgt gccctcaaaa cttcgtgaag aacttggcga aaagtttgtt ctgacacgcg
    19621 gattggatgg ctgtcttttc ggctatccga tgagcgaatg ggaaaatctg gaagctaaac
    19681 tgaacgaaat gccgttggct aaaaaagacg cacgtacttt tgtgcgattc ttctattcgg
    19741 ctgccactga atgcgaactt gataaacaag gacgaatcaa tatacccagc acgttaagaa
    19801 attatgcagc tttgacaaaa ggttgcgtag tcatcggtgt atctaaccga attgaaattt
    19861 gggatgagac acgatggcaa gatttttctg cagcagcaga agagaacttt gacgaaattg
    19921 ctgaaagtat gattgatttc ggactataag aataggaaga ggctgactaa tgactgaaac
    19981 atttcaacac tatacagtca tgttgaaaga aacggtagat ggattgaaca tcaaaccgga
    20041 tggcgtttat gtagactgta cactcggcgg tgccggacat agtgaatatt tattaagcca
    20101 actaagttct aaagggcatc tgtatgcgtt tgaccaagat caaaaagcaa tcgatcacgc
    20161 caagctgcgt ttagcttctt atgtcgaaca aggtatggtc acatttatca aagcgaactt
    20221 cagagaatta gaagaacgct tgagtgagca tgtagataag gtagacggca ttttgtatga
    20281 tctaggggtt tcctctcctc agctagatga agcagaacgt ggatttagtt atcatcaaga
    20341 tgcaccgttg gatatgcgca tggatcagtc agctccttta tccgcttatc acgtaattaa
    20401 tgaatattcc taccatgaat tagtaaagat tttcttccgc tatggcgagg agaaattttc
    20461 caaacaaatt gctcgtgaaa tcgaacgagt acgaaaaaca aaaccaatcc aaacaactgg
    20521 tgagcttgtc gaaatcatta aacaagtcat cccagctccc gcaagaagaa aaggcgggca
    20581 tcctgcaaaa agaatttttc aagctgtgcg gattgcagta aatgacgaac tcggtgccga
    20641 agaggcctct ttagaacagg caatccggtt attgaaagtc aatggaagaa tcagcgtaat
    20701 cacattccat tcattggaag acagaattgt caaaagtatg tttaaagaat atagtacggt
    20761 acaagatcta ccaccgggac ttcctgtcat acctgacgaa ttccaaccag aactgaaagt
    20821 cattactcgt aaaccaatcc ttccttcaga ggaagagcta acagaaaaca atcgatcacg
    20881 cagtgcaaag ttacgtattg cagaaaaaat aagaatgaaa gaggagtaga atgatggcag
    20941 aattaaagaa aatgcaagat tacgaatatg atttacctga attggtggat cagccggaac
    21001 aacaaatgcc tgattcttct tcgaatcaag aaatcattct tccacaatca ccggcaaaac
    21061 gattaaagca gatttctgct ttggaaaaaa ttgctgtggc aagcgtggcg attgctattg
    21121 ttgctttatg tgttttaaca gttatgctgc gcacaaatat cagcggagct gaaaaagaaa
    21181 tcacgtcaat acaaacagaa atcaatgata aaaagcaaga aaaaacgagt ttagaacaag
    21241 aaaaaaacga actttctcgt actgaacgga ttaaacaaat cgcagaagaa aaaggattgt
    21301 ctattaatga cgacaattta aggaaagtga agtaaatgag tcttaaaaat aaaattcggc
    21361 ggtttatgga aaagaaaaat ctaaatccga tgaacaatcg caaaaaagta ggtatcattt
    21421 tatttgctac gagtattgga ttgttctttt tatttgccgt ccgtttctcg tatatcgtta
    21481 ttggaggtca tgttgctggt acctcattag ctgaaaaaac aaaacagttg taccaaggaa
    21541 gtgaagtagt aaaagcaaaa agaggaacga tttatgatcg taacggtgtg gcgctcgcag
    21601 aagatgcctc ctcttattca attaaagcga tactctcaaa aacatatacc tctggggata
    21661 aaaaactgta tgttgaagaa aagaattttg ataaaatagc agaaatcctg cataagaatc
    21721 tttctataga caaaaaagat gcactgaata ttttagagga cggcgcaaaa aaagagctgt
    21781 atcaagttga atttggtagc tatgggaaaa atatctccca agaaaccaag caaaacatcg
    21841 aagcggacat gaaaaaagaa ggtgtcgctg gtctttattt tgtcgaccat caggctcgga
    21901 tgtatccaaa tggcgtcttt tcttctcatt ttattggata cgcagttcca gacaaagatg
    21961 agaatggctt agttggtaaa ctaggtttgg agtctgctta caatgatatc ttgagcggta
    22021 aagatggtaa gattatttat caaaaagata attttcaaaa tcctctgcca ggtacagtgg
    22081 cagaagaaga aaaagctgtc gacggacaag atatctacac gactttagac agcagactac
    22141 aaagttattt agaaacactg atggatcaag taaatgaaga atatcagcca gaagaattga
    22201 cagcagtcct gatgaaagca aaaaccggag aaatcttggc aatgggacaa cgacctactt
    22261 tcaatcctga aacaatggaa ggattgactg gaaaagatgc tatctggcgt aatttcttgg
    22321 tacaagatag ttatgaacca ggatcaacca tgaaagtttt cactactgca gctgctatcg
    22381 aagaaggaga attcaacgag aatgaaacct tccaatctgg aaaaatccaa gtagaagatg
    22441 ctacgatcaa tgaccatgac tttggtgaaa aaggtgtgct gaccatgcgt caagctcttt
    22501 catggtcaag taacgtcggg atggtcatac tggaacagcg attaggcgga cgatggtata
    22561 actatttaca aaaactggga tttggacaaa gtactcattc tggattagat gatgaagtaa
    22621 acggtgcttt acctacatta aatattgtcg accgagcaat gagtgcttat ggacaagcgg
    22681 taggtgtgac gaatttccaa atgatgaaag ctttcacttc tattgcgaat aacggtacaa
    22741 tgattcaacc tcgatatatc agcaaagtgg tggatcccca aactggagaa gagcgaacaa
    22801 ctcaaacaga agttctaggg caaccttttt caaaagaaac aacagaaaaa gtccgtgaat
    22861 atatgagaga tgttgtcgaa agcgaaaact acggtagtgc ttatggtgta tatagtgtac
    22921 ctggatacaa tgtatcggca aaaaacggaa cagcccaaat cgcttctgat acagggggat
    22981 atcaaacagg agatacagcc tacctgtatt cgattgtgga gatggttcct tctgaagatc
    23041 cagactatgt cttgtatcta acaatgaaac accctaagac atatgatcga atggcattgg
    23101 ctaaaatcgc aaatccattg atgaaacggg caatggattt taaagaaact gaagaagatt
    23161 cagatacaga aacaaaaaca gaaaaagtat ccgtagccga ttatcgtaat cttgaagcgg
    23221 acgttgcagc agctgatgct caaaaaagtg gactgcaacc tgtagtgatc ggtaatggta
    23281 aaaaagtaca aaaacaatct actgccaacg gtgatcagtt gatctctgga gaaaaactga
    23341 tcctatatac tggtggtgat aagctgatgc ctgacgtaac aggatggtca aaagcagata
    23401 tcatgaagct ggggaaaatc ctcggtattg aagttagttt tgatggagat ggttattgtg
    23461 tcaaacaaga acttgctcca tatgaaaaaa tcactgaaga caaacttagt tttactttag
    23521 aagaataaga agagaaatag gagagaaaag agcatggaat ggacacaagc attgattccc
    23581 attgtcagca gttgtgcaat gacaattgcc gcaatgccgc tatttattgg ttattttcaa
    23641 atgaaaaagc aaggtcaggc gattcgtgag gagggaccaa agtggcacaa tagcaaagcc
    23701 ggaactccta caatgggcgg cttagtgttt ctgatcggct ctattttgac aggaatttgg
    23761 gttggagctt ggcaaaaaca gctaactcct actcttttca tcttgctttt tgtattagcg
    23821 ttatacggag taatcggctt tcttgatgat tttataaaaa tattcaagaa aagaaacatg
    23881 ggactgaact cgaagcagaa attgattgga cagattctag ggggaatcat cttttatctt
    23941 gtttaccgtt ctgaaggtta tccaggtgta ttgaatttct tcggactaga tctaccttta
    24001 ggaatcattt atggtatttt cgctctcttc tggcttgttg gattttcaaa tgcagtaaat
    24061 ctgacagatg gcatcgatgg attagttgct ggcttaggaa gtatctcttt tgcagcttac
    24121 ggtctaattg cttggcatca gcatcagtat gatgtattaa tcatttgctt aagtgtttta
    24181 ggaggtttac tgggtttctt cgtctacaac agaaaacctg ccaagatttt tatgggagat
    24241 gtcggttcat tagcgttggg cggactttta gcggcaattt ctataatgct aaaccaagaa
    24301 tggacattgc ttttgattgg tttgatctat gttatggaaa cagcaagtgt gatgcttcaa
    24361 gttacttcct ttaagcttac aggaaaacga atttttaaaa tgtctccaat tcatcatcac
    24421 tttgaaatgt gcggatggtc ggagtggaag attgatacag ttttttggtt gatcagcatt
    24481 gtgacttcgt tgatcacatt atggatcgtt tggtaggaga tgacgggaaa tgaaaaaaat
    24541 atcaacatat gaaaataaga aagtgcttgt cttaggactc gcaaaaagcg gagtaagtgc
    24601 ggccaaatta ttacatgaat tgggcgcact tgtcaccgtt aatgatggaa aaccttttga
    24661 cgaaaatccg gaagcacaag agctgctttc tttagggata aaagtaataa caggtagtca
    24721 tccaatcgaa ttgttggatg aagaattttc attgatggtc aaaaatccag ggattcccta
    24781 cagtcatcct ttagtagcaa aagcccaaga aatgggtatt ccggtaatta cggaagttga
    24841 gctagcttac gaagtagcgg aatgcccaat tattgggatt acaggaacga acggaaaaac
    24901 aacgacaaca acgatgacag gactactact gaatgcagga gcagatcaag gaattgcacg
    24961 tttagcgggt aatattgggt atccagcaag tggtgtagcg caagaagcaa aatcagaaga
    25021 taaaattgtg atggaattgt ctagcttcca actcatggga atcacagatt tccgccctca
    25081 tatagcggtg attaccaata tctatgaagc acatattgat tatcatggta caagaaaaga
    25141 atatgtcaaa gctaaatgga accttcaaaa aaacatgaca gaaaaagatt atctgatcct
    25201 taactggaat cagtcagaac tacaagaatt agcgcaaaga acaaaagcac gcgtactgcc
    25261 tttctcgaca aaagaagtgt tggaagacgg tgtgtatgct gacgattact caatatacta
    25321 taaaaaagaa aaaataatgg aaatatctga acttggcgta ccaggtaagc ataatgtaga
    25381 aaatgcacta gctgctattt ctgtagcaaa attgtatggt atatcaaatg aagctatacg
    25441 agaaacgttg cattttttcc atggcgtacc acatcgtacg caatatgtag gagaaatcca
    25501 aggcagaaaa ttttataatg attcaaaagc aaccaatatt ttagcgacta aaatggctct
    25561 aagtggattt gaaacgtcta aggtcgtgtt attggctggc ggattagaca gaggaaatac
    25621 atttgatgaa ttaattcctt cattaaaagg aatcaaagca atggtcgtat ttggccaaac
    25681 aaaagaaaag ttgatggatg ctggaaaaaa agcaggcatc gagacaatag taacagccga
    25741 ttctgtagaa caagcagttc ctttagcatt agaaaacagt acagatggtg atgtagtttt
    25801 attatcacca gcgaatgcca gctgggatca atacccaaat tttgaaacta gaggaaacag
    25861 attcatggaa gctgtgaacc gattaaaata gaaaaagtag aagcgagcga taaaaaatga
    25921 aaattttggt tacaggcgga ggaacagggg gacatattta tccagctctt gcctttgtca
    25981 attatgtaaa gactcaagaa ccgaatgctg aattcatgta tgtgggagca aaacgaggtc
    26041 tagaaaacaa aatcgtccct gatacaggaa tgcctttcca taccttggag attcaaggat
    26101 ttaaacgaaa aatttccatg cataacatca agacggtccg attgtttctt aagagtatcc
    26161 gtcaagcaaa aaaaatcctc agtgattttc aaccagatat cgttatcggt actggaggat
    26221 atgtttccgg agcggtagtg tacgctgcag ccaaaatggg tattccaaca gttatccatg
    26281 aacaaaacag tgtaccaggt gttaccaata aatttttaag ccgatatgtg gatcggatcg
    26341 ctctttcatt taaagatgcg gcttcctttt ttcctgaaaa caaagcagtt cttgtaggta
    26401 atcctcgagc acaagaagta gcagatacta aaaaatcaga tattttgaaa acatttgatt
    26461 tggatccaga aaagaaaaca gtcttgattt ttggcggtag tcaaggagca cttaaaatca
    26521 atcaagcagt atcagttttt ttaagtgaat atattccttc ttcttaccaa gttttgtatg
    26581 cttcaggaga tagatattat gaagagatcc taaataaaat aaatcctgaa atacaaaata
    26641 ttagtgtcca gccttatatc aaaaatatgg cagaggtcat ggcttccagt gatctgctgg
    26701 tggggcgtgc tggtgcaact tcgatcgcag aattcacagc tctggggtta ccggcagtgt
    26761 tggttcccag cccatatgtt acgaatgatc atcagactaa aaatgcaatg agtcttgttc
    26821 acgcaggagc agcaaaaatg attgcagata atgaactaac aggtgaatca ctaagtcaga
    26881 cagtcaacga aatcatgggt gatgaagaat tgcaaaagca aatgtgccga gcttctaaag
    26941 aacaaggaat ccctgatgct tcaaaacgtc tttatgactt agtaaaacaa ataatcaaaa
    27001 aataaaggcg gtggtcttag tgagtaagaa aaaagaacca aaaaaattgt ctcatccgtc
    27061 ttctgatgaa aacaatttga ctccttggca aaaggctaac cgaaaatatc tggcagaaca
    27121 agagatgaaa aaccaagagc caaaaaaaga agacataaca ttagatacac ccctttcaga
    27181 ttctgaagaa gaaaaaacgg ttcaagagga acagcaagaa gaaagccagt ccgagaaaaa
    27241 aatcgaattt tttgaagaga tcaagcaaaa gaaaaacggt ggaccatata acggttcttt
    27301 tttgaaccgg ctgcccaatt taaaaagtca acggcacaaa gtactatttc gtcggttagc
    27361 tttgatcatc actgtattgg gtataccgct gatttttttg atctattatg tttctcctta
    27421 tagcaaatta caagcagttg cagtatcagg caataagaca gtcaacagcc aagaaatcat
    27481 ctctgataca aaattgtcat taggagaaaa tgtttgggga cagtattttc atcgatctac
    27541 ttatatcgat cgccttaaaa aagcacagcc aagaatcgaa acagcaaata tacatttcaa
    27601 agggatgaat gaattcgatt tggatgtaac agaatataaa gagattgctt tgatcgcaaa
    27661 aaacaatcaa tactacccag tgattgaaaa tggaacagta ttagatgaaa aagtagcaaa
    27721 tcctacaaaa aatctcccta tcttggaaga gttcaaagac tctgcaaaaa tcaaagaatt
    27781 aacaaagcaa tacaatcagt tatcatcaga attacaaaaa gcaatttctg aaatcaagta
    27841 cacgccaaga gcaagcaata aaaatctgat ccaattgaat atgaatgacg gcaatcaagt
    27901 tattgtaaat atcaataatc ttgcgaacca aatgaaatat tattcgcaag tagccaaaga
    27961 tatggatgaa aaaggtgtga tcgacatgga agttggtatc ttctcgcatc cttacggtag
    28021 cactcaagaa acggaagaat cgggccaatc ggaagaaaca actgaaagtg aagaaaatgc
    28081 ggatcaaaca aacgaatcaa gtgaagaggc agaaacgcaa aaagcacaaa cacctggatc
    28141 gtctagcaca aacggatcat ctgattcaaa tgattcaagt gaaacaagtc aaatagaaga
    28201 taatccaagt acaactccgt caagtttaaa tgaaaattga taaaacaact ttaaaaagta
    28261 agaatgtact ttctaaaaac cagtaattta tggtagaatt ggaagcagtg aatatatcta
    28321 ttaataagta tattttaaaa cggacgctag ttgttcgctt gtatatggaa tagtaagtag
    28381 gagggaatcc cattcatggc aaaaacagga atgtatgtag gccttgatat tggaacgaca
    28441 tctgttaaag ttgtcgtggc tgaatatatc gacagccaaa tgaatattat tggagtagga
    28501 aacgcaaaat cagaagggat taaccgaggc attatcgttg atatcgataa aacggtccaa
    28561 gcgatacaac gagcagtacg acaagcagaa gaaaaagcag gtatccagat caaaggcgta
    28621 agtgtcggtt tgccagcaaa catgcttgaa gtagaaaatt gccagggaat gattgcagtt
    28681 aacggagatt caaaggaaat caccgatgaa gatgtcagaa atgtggcttc agctgccctt
    28741 gttcgttcaa tacctcctga acgtcaaatc gtgtcaatat tgccacaaga ttttactgtc
    28801 gatgggttcg agggaatcaa agatcctcgt ggaatgatcg gcgtaagatt agaaatgtac
    28861 ggtctgttgt ttacaggacc taaaacgatc atccataaca tacgtaaatg cgtggaaaat
    28921 gccggattaa tcgtcaacga aatggtgatt actcctttag cgctgactga atcaattctt
    28981 tctgacggag aaaaagattt tggtacgatc gtcattgata tgggtggcgg ccaaacaaca
    29041 acggctgtta tgcatgataa gcaattgaag tttaccaatc ttgaccaaga aggtggcgaa
    29101 tttgtcacta aagatatctc tattgtatta aatacgtcat ttaacaatgc agaagcgttg
    29161 aaaataaact acggggatgc atacccagaa cggacatcac cagatgaaga atttccagta
    29221 gatgtgattg gtcagtcaga accagtgaaa gtcgatgaac gctacttgtc agaaattatt
    29281 tcagctcgaa tggaacagat tttcaacaaa gcaaaagatg cattggacca aatcgaagca
    29341 ttagagttgc caggtggcgt cgtattgaca ggcggagctg ctagtcttcc tggtgttgtg
    29401 gacttggcac aagaaatctt cggcgtaaat gtaaaattgt atgttccaaa tcacatgggg
    29461 ctgagaaacc cggtatttac aaatgtaata agtatcgtgg attattcagc aaacttgagt
    29521 gaagtgtatc aattggcaaa aattgctgtt acgggtgaaa cctcagcagc tcgtcaaatg
    29581 gtagttgaac aagaaacaac aaacacatat gagagctatg aagcacctga agaaacaatc
    29641 tacgatgagc cggaaccaaa agagtccgga gaaaatgtaa aaaataaaat caagggtttc
    29701 tttacaaata tttttgatta attcatcctg ggaggaataa gatatggaat tctcaattga
    29761 taataatatc aatgacggcg cagtaatcaa agtcatcgga gtcggtggtg gcggtggaaa
    29821 tgctgtaaac cgaatgattg aagaaaacgt taaaggtgtt gaattcatta cagccaacac
    29881 agacgtgcaa gcattaaaaa attcaaaagc tgaaacagtt atccaattag gccccaaata
    29941 tactcgtggt ttaggtgctg gttctcagcc agaagttgga caaaaagcgg cagaagaaag
    30001 tgaacaatcc ttacgcgaag ctttagacgg tgcagatatg attttcatca ctgcaggaat
    30061 gggtggagga accggtacag gtgctgcacc aatcgttgca ggtatcgcga aagaattggg
    30121 cgcattgact gttggtgtcg tgacacgtcc attcactttt gaaggaccga aacgtggccg
    30181 ttttgctgca gaaggtatcg ctcgtttgaa agaaaatgtg gatacattat taattatctc
    30241 aaataaccgt ttattagaag ttgtagataa aaagacaccg atgcttgaag ctttccgtga
    30301 agcagataat gttttacgac aaggtgtaca aggtatctct gatttgatca cagcgccagg
    30361 ttacgttaac cttgactttg ctgacgtgaa aacagtgatg gaaaaccaag gtacagcatt
    30421 gatggggatc ggtgtggcta gtggagaaga tcgcgtagta gaagcaacga aaaaagcaat
    30481 ctcctctcca ttgcttgaaa catctattga tggagctgaa caagtacttc ttaacatcac
    30541 aggcggtttg gatatgacat tgttcgaagc acaagatgct tcagatatcg tagcaaatgc
    30601 agcaactggc gatgtaaata tcattctagg tacatctatc aatgaagaaa tgggcgatga
    30661 aatccgtgtg acggtcatcg caacaggtat cgatgaatca aaaaaggaac gcaagtctag
    30721 ccgaccagct agacaagcac aaatgcaatc acctgctcaa aagactgtat tagatatgga
    30781 tcaagctaaa ccaacttctt cagaagaaga aaacagtttt ggcgattggg atatcagacg
    30841 tgaacaaaat gttcgtccta gagttgatga ttccaatttt gacaatatcg aaaaaaaaga
    30901 atttgataca ttcaaccgcg aagaaacaaa atctcatggc gatgatgaat taaatacgcc
    30961 accgtttttc cgtcgtaaaa aataaaggag aggaagagca catgattgct gacaacttgc
    31021 agaaaatcaa gcaagaaatt caggattcgt gtgctcttgt tcatcgtgat ccgaaagaag
    31081 ttacattagt agctgtaaca aaatctgttg aatccgctca agctgaagaa ttggttagag
    31141 ctggcgttat gaattgtgca gaaaaccgag tagataaatt attagaaaag aaacaagatt
    31201 tatttgattt tcctgaaata aagtggcatt taattggtaa tttacagcgc agaaaggtaa
    31261 aattgattgt aaatgaaatt gattactttc atgcgttgga cagtttaaga ttagcagaag
    31321 aaatccagaa gcggttagag aaagaattat cctgttttat tgaagtaaat gtttctggtg
    31381 aggaatcaaa acatggaatt tcaccagatg agcttttacc gtttgtggaa tctttagctg
    31441 cctgcacaaa aatcaaggtt gttgggttga tgactatggc gcctaaagaa gcttctgatg
    31501 agcaaatcca taaagtgttt ggtacgctga aagaattgcg tgatcttgtt caagcaaaag
    31561 gttatgccca tgcaccatgt agtgaattaa gtatggggat gagtcaagac tttcaaattg
    31621 cgattgaaga aggtgcaaca tttatccgtg taggaacagc gctattcaaa gacgaataaa
    31681 ggaggaacaa aaatgccgct tttaaacaga ggagcaattg ctaatttttt cggattagct
    31741 gatgaggaag agtacgaata ccaagattat cctgaaacaa caaaaaaggc tgtacagcca
    31801 actaaaaaaa atacaacaca gaatcaatca actcattctg tatctgctgc gaatactcat
    31861 gaaaaacaaa aaacggcgac ttcacgtcct gtaacgcatg aaagtattca gccggctgaa
    31921 aagaaaaaag taattgaact acatcaatca cctacaaaaa ctgtagcgaa agaaagaaca
    31981 gcttcaagaa cctctacaca acctaaagca aatcttgctg gaaaaatcac tgtaatggaa
    32041 ccaagagctt attctgaagc tatggcgatt gctaaacgaa tcattgctgg agaagcaacc
    32101 ttagtgaatt ttcatttagt agaagaaaaa caagcgagaa gaatcgttga ttttctaaca
    32161 ggaacagttt atgcactaga tggagatatc aaacgtgttg gagatgagat ttttctttgt
    32221 acaccgactg ggatggagat tgacagttca accgctcaat cttttgcaga tgcgaatttg
    32281 tttgatctgt aagaggagga actacgattt atactattgc actattactt catttacttc
    32341 aacgggcagc ctatttctat agcattatct tgatggtata tgcattgctc tcttggtttc
    32401 caggcgggta tcaatcaggg ctaggacgat tattagctaa gatctgcgaa ccgtatatca
    32461 gtttgttcga tcgtctgcct ttgaggattg gacccttgga tttcacaatt ttaggggcaa
    32521 tcctgatctt gaacttagcc gtacaaggtt tagcacagat cgttatatgg ataactgtcc
    32581 atttagttta ttgattgaag caacaaaatc tttattctca gaatagatag gaggggaaaa
    32641 ttttgatgca aatgtatacc agcactttcg ggcagatgaa cgtacattta tcgattcggt
    32701 aggcgattgg attgaacagg ttcaaggaca atatgcaccc tatctgaccg aatttcttga
    32761 cccaagacaa tcctatattt tagaaacact gattcgacaa agcagtgatt tgcgtttcat
    32821 gttttatggc ggatatgaac aggcagaaag aaaaagatgt ttgattttcc ccgattatta
    32881 cgaacctgta gaggaagatt ttgaaacagc attgtatgaa atccattatc ctagcaaatt
    32941 tgccagccta agtcatggga aaatccttgg aactttagtg ggaacgggga tcaaacgctc
    33001 ttactttggc gatatcatct cggacggtga tcgctggcaa gtatttattg caaatgaggt
    33061 ggatcatttt gttgctgcac aagtaacaaa gattggaaag gttgctgtac gcttggaacc
    33121 aatcaaatac acagaaatga ttatgccgaa agatagctgg acacaagaaa gaggaacagt
    33181 tagttccatg cgactagaca gtgtgatctc tgagatttat aatatttcca gacagcggtc
    33241 caagcagctg atcgaagctg gtaaagtaaa agtgaactgg acagaaaata caagacctga
    33301 ttttgtactt gaactattag atattatttc agtcagaggt tatggcagag tccagatcca
    33361 agaacttgag gggaagacga aaaaagaaaa gtacagggta ctgttcggtg tattacgtaa
    33421 ataaaataaa aaggtggttt actcatggct ttaactccat tagatatcca aaataagaca
    33481 ttcccgacaa aaatgcgggg atataatcaa gacgaagtag atgatttctt agatttagtt
    33541 gttcgtgact atgaggaatt gactcaaaga aatcgagaat tagaaaaagc agtcaaacat
    33601 tctgaagaaa aacttgagta cttcaatgaa ttaaaagatg ctttgaacca atcaatcatc
    33661 gtagctcaag atacggctga taaagtaaaa acaagtgcaa gcaaggaatc cgaagtgatc
    33721 gttacttctg cacaaaacaa agcagatgag ttagttgcga acgctgaaaa acgtgcacat
    33781 caattaacaa ctgatgcaga agaaaaagca agaaaaatct tgacagatgc aacagaaaaa
    33841 gcaagacagc ttgcgacaga aactgaagat cttaagaaaa aaacacgagt attccatcaa
    33901 cgtatcagct tgatgcttga gtctcaatta gaacaagtga aaagtccgga atgggatgaa
    33961 attttacaac cattctccag ctacgtgact gacagccatg aagtgatcaa agaagtttta
    34021 gcaaaacagc ttgacaatga aaatgatact gatgtaaact cagacacagg agtcatagaa
    34081 gcacctatga cggcatttga tacacaggct attgatatct cgatcgtgcc tggtgaaaat
    34141 gaaaacgagt agaacagaaa agcactttgt tattcttaaa gcgagccgat gagagtggaa
    34201 gttcggtaag acactgcatg gtgaaagatc ctctacttga gacctgcttt tccgaaatta
    34261 gagtaagaag cagcggctga cctcgttatt ggtcacagag agtttgcact agatagatgc
    34321 aactaaattt gggtggtacc acggcatgtt cgtcccttgc ggctgaacat gcttttttgt
    34381 gtccggaaaa caaataaagg agtgtatggt tgaatgaaaa tgaaagaaac cttgcaatta
    34441 ggaaaaacaa aattccctat gcgtggtaat ttgccaaacc gagaaggcga gtggcaaaaa
    34501 gaatgggaag aaaatcgaat ctaccaaaaa agacaagagt tgaacgaagg aaaacctagc
    34561 tttgttcttc atgatggacc tccatatgcc aatggtaata tccatttagg acattcattg
    34621 aataaaatca gtaaagacat tatcattcgt tcaaaatcaa tgtctggcta tcgtgcacca
    34681 tatgttccag gatgggatac acatggattg ccgattgaac aagtattggc taataaaggc
    34741 gtgaaacgta aagaaatgtg catggcagaa tacttggaaa aatgtcgtga atatgcactt
    34801 tcccaagtag ataagcaacg agcagatttc aaacgcctag gagttgcagg agattgggaa
    34861 catccttatg ttacattaga tccttcttat gaagctgcac aagtacgcgt atttggtaaa
    34921 atggctgaaa aaggctatat ttacaaagga ttgaaaccaa tttactggtc tccgtcaagt
    34981 gagtcttctt tagcggaagc tgaaattgaa tataaagatg taaaatctcc atctattttt
    35041 gtagctttca atgtcaaaga cggcaaagat attcttgatg aagatacagc ttttgtcatt
    35101 tggacgacaa caccatggac attgccagca aaccaaggta ttgctgtaaa tccaaaattt
    35161 acgtatgtat tggtggaagc cgatggccgt aagtttgtcg tagcgaaaga tttgctagaa
    35221 acagtccaat cagaaatcgg ttgggaaaat gtaacagttc taaaagaatt tgctggacaa
    35281 gaaatggaat atatgactgc aagtcatcca ttctatgaac gtgaatcact tgtgatttta
    35341 ggcgatcatg ttactttaga cgctggtact ggattagtcc atactgctcc aggacatggg
    35401 gaagatgact atatcgctgg tagcaaatat aaactatctg tagtgtcacc tgtagactca
    35461 aaaggattgt ttacagaaga agcacctgga tttgaaggta tcttttatga caaagcaaat
    35521 cctatgatca ctgatctatt aaaagaaaaa ggagctttgc tgaagctaga tttctttact
    35581 catagttatc ctcacgattg gcggacgaaa aagcctgtga tctatcgggc aactccacaa
    35641 tggtttgcat ctatcgataa attccgtcag aatattttgg atgaagtaga aaaagtagag
    35701 tgggttatcc catggggtaa aacacgtttg tataatatga tccgtgaccg cggcgattgg
    35761 gtaatttccc gtcagcgtgc atggggagta ccacttccga ttttctatgc tgaaaatgga
    35821 gaagcaatca tcacaccaga aacaatcgaa catgtggcaa aattatttgc tgaacatgga
    35881 tcaattatct ggtttgaaaa agaagcgaaa gaacttcttc ctgaaggatt tacccaccca
    35941 ggttctccta atggcgaatt tacaaaagaa aaagatatca tggatgtctg gtttgattct
    36001 ggttcttctc atgaagctgt tttacgtcag cgaccagaat tatcattccc agcagatatg
    36061 tatttagaag gatcagacca atatcgtggc tggttcaact caagtatcac gactagtgtg
    36121 gctatcaatg gtgtagcacc atacaaatca gttatttctc aaggatttgc tttagatggt
    36181 gaaggccgta agatgagtaa atctttagga aacatcattg caccagaaaa agtgatcaaa
    36241 caatttggtg cagatatcct tcgcttatgg gtatctagtg tagattatga agcagatgtt
    36301 cgtgtttcta tggatatctt aagtcaagtg gcagaagtat atcgtaaaat cagaaatacg
    36361 atgcgtttct tattagcgaa tacagaagat ttcgatccta aaaaagatac tgtttcgtac
    36421 aatgatttac gttctgtaga caaatatatg accgttcgat tgaaccaagt aatcaaagaa
    36481 atccgagaag aagggtacga caaatataac ttcatgcata tttaccgtac agttatgaac
    36541 ttcttgacgg ttgatctatc gtcattctac ctggattttg ctaaagatgt agtttatatt
    36601 gaagcagaag atgattatca acgtcgttgc atgcaaactg ttttctatca aacagctgta
    36661 gctttgacaa aattattgac tcctatcatt ccgcatacag cagaagaaat ctggtcattc
    36721 ctgaaagaag aagaggagta cgttcagtta agcgagtttc ctggttatga agagtttgca
    36781 aaccaagaag aattgatgga tacctggact gctttcatgg acttccgtga taatgtctta
    36841 aaagcattgg aagaagcaag aaacagcaaa ttgattggta aatctttgga agcaaaacta
    36901 actgtttatc caaaacaaca agttcgtgaa atgttaaaag ctttggatgc agatattgca
    36961 caattattga tcgtttcacc agactacttt gaagttatgg cagcagatga acaagtgcca
    37021 gataacgcta tggtatttga tgatgttgct attacagtgg aaaaagcaga cggggaaact
    37081 tgcgatcgct gtcgccaagt tcgtaaagat gtaggagtag atgaaaaact tcctcatcta
    37141 tgcggtcgtt gtgcaaaaat cgttgaagac ttctatcctg aagctgtagc tgaaggattc
    37201 gaagaaaagt aaaagggaaa agggggtgtg acatgttctt tgtcacaccc ccttttgtta
    37261 tcaatcgttt aattttccac gttcacgata ccagttatct ggttgccaga tccattcgaa
    37321 tccgtctttt tcaagtagtt cgaaagctgc tttaggtccc attgatccag ctttgtagtt
    37381 gggaaaatcc ggttgtgttt ggtcccaagc ttttcgaatg acatccacga tatgccaaga
    37441 ttgagcgact tcttcccaat gagagaagtt cgttccatca ccattcaacg catctaatag
    37501 taatttttcg taagcttctg ggctattttc aaccatttct gcactatttc taaattccaa
    37561 tttgattggt tccgtttcaa atccttgccc tacttctttc ccattcaagg ataaagaaaa
    37621 tccttcagtt ggctgaatat agatcgttag aacattaggt ggaagtgtcg tatcgtcaca
    37681 tggttcatcg acagatgttt tgaatacatt aacaggaact tgtttgaata cgatgttgat
    37741 ccgagtccct ttttcagtca aacgtttgcc tgtacgtaca tagaaaggaa cacctgacca
    37801 acggaagtta tcgatagtga atttgcctgc gacgaatgtt tcagtctctg attgagcatc
    37861 cactttgtct tcttcgcgat agcccttgaa ttgtacacca tccaattcac cttgagcata
    37921 ttgcccgcga acgaagtttt ctaacacttc ttcttcgtta taaatgcgga tagctttcaa
    37981 tgctttgatc ttttctgtac ggatttcttt ttcggaaaat gctactggcg gttccattgc
    38041 aagtaatgct acaacctgta aaatatgatt ttgcaccatg tctttaagtg cgccactatg
    38101 atcgtagtag cccccgcgat cttctacacc gaggttttcg ccaaaagtaa tttggatatt
    38161 gtcgatatag cgattgttcc attgagcctc aaaaatatta ttggcaaaac ggatagctga
    38221 gatgttttgg atcatttctt ttcctaaata atgatcaatc ctgaaaatat cttgttctgg
    38281 gaatacttct ctgatttgct ggttcaattc aaaagcagac tggtaatcag aaccgaacgg
    38341 tttttctatg atcaaacgat tgaagccatt ttttgtcata atattttgtg atttcaaatg
    38401 agaaacgatc gttccaaaaa attgaggtgc catagccaaa taatagacac ggttaccgtt
    38461 taattgatag tgtccatcta atcggtcaga caattctttt aatgtctgat aatgcgttga
    38521 atcatttaca tcatgggatt gatagtaaaa atggcttgca aaggtagttg cttcttcatc
    38581 tgaaggattc aatgcacgga ttgtttcttt gacaacttca cggtagtgct catcgctcca
    38641 gggacggcga gcggttccga ttacagcaaa atgctcgcct aaatttcctt ttctgtaaag
    38701 gcggaacaaa gacgggtaca atttacgctg ggctaggtca cctgtaccgc cgaatatcgt
    38761 aaacaataca tttttttcat tagacatgtg gatacactcc tttatatttt atcgacaaaa
    38821 atcgtgctgg ccgccttaaa gctgacgggg attttctttc tatcattttg gatagtgatc
    38881 ggtccttcat aagctgcgat gtcaacgatc tcatattctt cgttgatatt caggtcaata
    38941 gtgactaagt aatccaacaa ttctttttca tcaagcactc gtgcgatacg cacttttgta
    39001 ccgacaggat aggactccaa tgtttgtcgg cgttcttcat ggacaacttc ctctttttta
    39061 ggaatcgatc ctccatgagg acaatgttca ggatgattca aatagttttc taaatgatct
    39121 gcaagatgtt ccgaagtcac atgttccaat acttcagcat catcatggac ttcattccag
    39181 ctatagtcta aatgttcaac taaaaaaact tcccataagc gatgtttgcg aatcagactg
    39241 ctagcttttt gcagtccgct tgcagtcaat tgtacacctt gataagggga atgttctaca
    39301 agctcttctt tcacaagttt agaaatcatt tcactgacag atgcagctga gacatctaga
    39361 ctagatacga tttgtttatt gttgactttc gttgtatctc cacctagttc taaaatgatt
    39421 ttcaaataat cttctcgatt tggtgtcata ttcgatcatc ctttcatggt aaaaaaccat
    39481 cattagtaag tgtaacaaaa aaaacgttaa ttgactattt ttctaaataa aaaacaaagg
    39541 atttttagac gtttttacaa caaaaaacga aagatgatag agaagactca ttctttcgtt
    39601 tataaaggat atatatatac attgggaggg atctattttt cagataacaa cttatatgaa
    39661 gtgtctgcag attcgtcata aagagtttgt tcgggataag aaaagataag ataaaaacca
    39721 tactgatcac gtacgactaa acgatattca tctatttcta ccacagatgt gccaagagac
    39781 tgaccgttga tcaaaaacgt gtaatcagat gtaatctgta attgttgttt ttgctggcta
    39841 tcactaaaga accatgtacc ttgatacttt gagagtcctt ctgacttttc cgcttgtttt
    39901 ttctttttca agtaaataaa acttgagaga acggtaatga gtgaaccaag aaaatagatc
    39961 atttttttta tcaccaaatc actcctttat gagaaaataa tcgcatagac atattctttc
    40021 ttctttattt cattgtaccg aataaaagct aaaatttctc taagactttc gactggtttt
    40081 tttactgttt ttctacaaat tatgatagga tacatagtag gaagaaaggt gacataattt
    40141 gaagtatcag caagtggaaa tagctttttt tattgaccgc ccgaatcggt ttatagcaca
    40201 ttgtatgaaa aaagacggag aaataattat tgcgcatgtc aaaaatacag gtagaggaaa
    40261 agaggtcctg ataccaggcg ctgaagtggc tattgtattt gctcctggac ctaaacggaa
    40321 aaccgcctat gatctgattg ctgtaaaaaa gaagggtgac tggtttaata tcgatagtca
    40381 attgcctaat cggctggcaa ttgatggtat tttagacggc acgatccttt taccaggatt
    40441 aactggtcca tttacggtat acaagcgtga agtaacttat cttcactcca aatttgatat
    40501 ttatttagag acggtggtcg gacaaaaagc atttgttgaa gtcaaaggta tgacacttga
    40561 aaataaagcg attggtgctt ttcctgatgc gcccacactc agaggattga aacatatagg
    40621 agaattaacg tatgccgcac aagatggtta tgccgcttat gtcttgttta ttgctcagtt
    40681 cgaacatctt catctggcaa cgatccatga agaaatgcaa ccagcactag ctgatatggt
    40741 tcgacatgcg cagcaaagcg gagttcaaat cctcgcctat aattgtcaag tatcggcaga
    40801 tgaggtaact gtcaagcagg ccattccatt tgatgtagat atcccttttg aagatcctat
    40861 acaatagaaa gaaggtaaaa taatgatcaa cttaggtatt atcggaacaa attggattac
    40921 tcatcaattt gtccaagcag ctttaagcac aaaaaaatat gaattgacag cggtatattc
    40981 tagacatttg gaaaaagcac aggaatttgg ttctcattat gaaggggata tcgaattcgc
    41041 aacagatttg aagacttttt tcaatattac tcatatggac accatttata ttgcttctcc
    41101 gaatagtctt cactttagtc aagctaagca agcaattttg gcaggaaaaa atgtgatagt
    41161 tgaaaagcca gctttttcga cgccaaaaga aatggatgaa atcatccatt tggcaaatga
    41221 acacaatgtg tatttttttg aagcagcaag aaatatccat gaatcaggtt ttaaaaagat
    41281 tgccgattac ttaccattaa aagacgagat aatcggtgca aatttcagct atatgaaata
    41341 ttcttcgcgc tatgaccaag tattagatgg agaagaaccg aatatcttct cgactcattt
    41401 ctcaggtggt gcattgatgg atttaggtgt ttaccttgta tatgcagctg ttgcttggtt
    41461 tggaatgcca aaagaagtcc attatttccc aagaaagatt tctactggtg tagatggtct
    41521 tggatggggg atcttacgtt atgagaattt tgatgtatcg atccagccag gtaaaatcgg
    41581 tgattcttat ttaccgtcag agatttattt tgactcagga acgctagtga tgaatggagt
    41641 caatgcaatt gaacaagcac aatttcatga tcgcgcgcat aaagaaatca ttgatttggc
    41701 ggtaacagct gcagaaaatc caatggcaga tgaagcagag gattttgcca atgtcatggc
    41761 tcatccgaaa gatccagctt ggggattgtt gtatgaagag tggatcgagc tagctagaaa
    41821 tgtgaaccaa gtgatttatg atttaagaaa aaatggcggc atcaaattcg atgcagataa
    41881 tgaggaagat ttttaatgaa cgaatttgta caagtatttc ccgaaaattg gcagaaaaaa
    41941 tatgaggata aagggtttat ctcaccttct cttattcaac gagcagtttt tcagccacta
    42001 agtaataaac aaagtatagt agcggtttct cctacaggtt caggtaaaac actggcttat
    42061 ctttggcctc tactactaaa cgtggaacca ggtgaagcaa gtgcgttggt catttttgct
    42121 tcttctcaag aactagctat tcaagtagca gatgttgcac gtgaatgggg aaaagacaaa
    42181 gagttgaaag tccaatcttt ggtgggcgga gccaacgtca aacgtcagat tgagggtttg
    42241 aaggaaaaac cagaaatctt gattggtaca ccaggaagaa tattggaatt gatgaaagca
    42301 aaaaaaataa aagcacatca agtgaaaaca atggtatttg atgaagcaga ccagctattt
    42361 gacgctggga acagccaaat cattgatcaa attcttcatc aagctccaac agagtatcag
    42421 ctagcttttt tttcagcgac agcagatcgt tcccttgaaa gcattgaaaa aatcactggg
    42481 aaaacgtttg agacaattga cgtgacagca gaggacgatt ctcgaaaagg actgagacat
    42541 tactttttac gtgtaccgat acgaaagaaa gatgactact tgagacgtct cacgcatata
    42601 gaagattttc atggtctgat tttctttaat caactgactg aattaggcgt aatggaagaa
    42661 aaattgctgt atagaggtgt accggtagga agtctggcct ctgatcagaa caagctactc
    42721 cgaaaagcag cgctagaaca attcaaaaag aaaatggtca gagcactttt gaccacagat
    42781 gtggcggcta gaggtttaga tattacaggt cttccttatg tagtgaatgc agaagttccg
    42841 ttaagtgaag aagcttattt gcatcgttcg ggaagaactg gtcgaatggg taatgaagga
    42901 atagtaatta cactcgtaca agataataat ctaagagatt taaaacggct tttacgtcca
    42961 tcaaatataa cacttgaaga gattttttta tacggaggta agctgcaaac tgagcagcca
    43021 accaaagaag atgcagctcc tgcagtaaat aaaaagtatg cgaaaacttt ttctggaaag
    43081 gagcagaacc cagaatataa caaagaaaaa ataagaaaaa aagttaaaaa taaatcaaaa
    43141 aaagagagaa ataaaggagc aaggcgcaaa taagcgcctt tttatgctat gattatgaaa
    43201 acgggaacaa aattggttgc cagaggaggg gttatgtgaa agaacgtcaa gaagagatct
    43261 tgcagctatt gacagaaaac caacaaggat tgacagcaag tgatgtagct gagcgcttaa
    43321 ctatcgatcg aagcaatgca agccgatatt taagtgaact atacaaggcc catcatattg
    43381 taaaaaccgc tggccgacca gtcgtttact ctttgccaac ggaaaagtca aaatctgatg
    43441 aagtgcatgt cgactcttct acgcaagtga cttttgaaac actcgttgga gaaaatgatt
    43501 ctttaaaagt cagcatacag caggcaaaag ctgcgattct ttatccaccg cgggggttgc
    43561 atacgattat ttttggagaa actggtacag ggaagtcgat gtttgctgaa tgtatgtatc
    43621 attttgcaat cgattcagag atgctttctg cagatgcgcc atttgtttct ttcaattgtg
    43681 cggattatgc tcaaaatccg caactgctct ttggacacat ctttgggatc aaaaaagggg
    43741 cttacacagg agcagctcaa gatagtcccg gtctaatagc caaagcagac ggcggtatat
    43801 tgtttttaga tgagatccac cgtttaccgc cggaagggca ggaaatgctg tttactttca
    43861 ttgataaagg tatttaccgt ccgcttggag aaagtgcaca agtacatgaa gcatctgttc
    43921 agatcattgg ggcgacgact gaatcttcag aaagtttctt atctacgttc aatcgacgga
    43981 ttcctatggc aatcaccttg ccgaatcttg cttcacgttc actggatgag cgttatgaaa
    44041 tcatctctct ttttatcaaa caagaagcga atcgtttgaa tcaacgtatc gatatcgaaa
    44101 aagaagcgat tcttgccttc atgctttatg atgcggaagg aaatatcggt caagtgaaac
    44161 gagacttgaa actagtctgt gcaaaatctt ttttacatta ccgtactcat catgagaaaa
    44221 agctaatcat tcgaaaagaa gaactttccc ttcaagtaca aaaaggatta ctgaaaatca
    44281 aggaaatacc ggaacgtctc gaccgattca tggacagcaa aagtcagtat ttgacatttg
    44341 aaccaggatt tgctgatgtt gtctggtcac aagatccaga acgaaacatg caggtctata
    44401 acgatattga ggaaaaagtc acttctcttt ccgaaaccgg tgtggagaac attgatctag
    44461 agaccctcat ttcaaaagat gtggatgctt atttccagac atatgtcaaa gaattgacta
    44521 aaagttcgat tcccaaagat cttttgccag atgaaatctg gcggttaacc aatcaattgt
    44581 atgatgtggc tgaaaaacgg ttagaccgta tttataatga aaaagctcgt tttgcttttg
    44641 ctttgcatct gcaaagtaca ttggatcgtg tgagagaagg tcatatgatc gtccacccag
    44701 atttgaataa cgtacggaaa aattttaaga gggaattcca ggtagcaatc gatctttcaa
    44761 cgatcattga agaagaagaa caagttgaga ttccttttga tgaaatcggc tttattagta
    44821 tgtttctttc tatcaatcta ggagaaagtg agcctgttaa agaaaacaaa gtagatgttc
    44881 tcatattgat gcacggcaga cagactgctt caagcatgtt ggagatggca caagaactat
    44941 taggaacaaa agtagggaaa gcttttaata tgccactggt tatggaagtt caaacaatgt
    45001 atgaagaagt gttacaatat gtcaaaaact atcaagagca tttgacgaat ggcctactct
    45061 tgttaacaga tatgggatca ttaaacacct tcagtgattt gatttatgaa gagactggca
    45121 ttcggacgaa agctatcacg atgacaagta ccatgattgt gatagaagcg atacggatgg
    45181 caagtgttgg aagaagctta gaagatattt atcaaaatat ccagctttcc tttgaatcga
    45241 tcgtacgtga tcagttcaaa gcggaaaagt ctgaaacttt acagcgtaaa aaagccgtaa
    45301 tcgtgacatg ctttactggt gaaggagtag ctgccaaatt atatcagcgt attatgccag
    45361 tgattaatca aaataaggta gaactgatcc agatgcagtt tttagaacgt gaatcattca
    45421 aaaaacacat cgatgcctta ttggaagaat atgagatcaa agcaattgcg ggaacagttg
    45481 atgttgatta tcaaaatatc ccattttttt cagcctatga cgtttttgat gatgaaaaac
    45541 taaatatttt aaagcgtata gctgatgatg agatcccgac agctaaaatt gtcgattcac
    45601 ttgctggatc attaagcgat gtcttttcta ttgatgaact gatccgttca ttgcaaaaga
    45661 cagttcagca gatccagacc gatttgtcga ttatcgtgga acctggagta gatactggaa
    45721 tcgttatcca tttagccttc atgttagacg gattgatcaa acaagaaagc catcggcaat
    45781 ttgagaaact gtctattttc tcaaaaattt atcgtttgga aatggatatc gttcgggcaa
    45841 acttgatggc actagaacga aaatatcagg taaaaattcc agaagatgat atcgcatttc
    45901 ttacacaaat gtttcttgaa aataaaataa aaaaatgaac acactaatca tactgtttac
    45961 acactaaaca tctgtgtgcg cactataaaa aagagctaaa aagcatgaaa acgctatttc
    46021 agctcttttt tttattggca tgcttcttgc gttatataaa agtgtaaaaa aataaaagga
    46081 gtgttaaaaa tggcaaaaaa aacaatcatg ttagtttgtt cagcagggat gagtacgagt
    46141 ttattggtca caaaaatgca aaaagcagca gaagaaaaag ggatggaagc cgatattttt
    46201 gcggtctctg cctcagatgc agataataat ttagaatcta agaatgtcga tgtattatta
    46261 ttaggtcctc aagtacgttt catgaaagct caatttgaac aaaaacttgc gcctaaaggt
    46321 attccattag atgtcatcaa tatgcaagac tatggcatga tgaacggaga aaaagttctt
    46381 gcacaagcag aaaatctaat gaaataaatc aagtatgcag ttgggggtat aacaacgtgg
    46441 aagatcaaca aaatctagaa gccatcatgg ggttaatcat gtttggcggt aatgcaaaga
    46501 gcgatgcaat ggaagcgatt gcggctgcta aaatcggtga ttttgagtta gcggatagga
    46561 aaatcgctga tgcagaagaa tcacttatac aagcgcatca tgcacaaaca gacatgttga
    46621 cacaagaagc acaaggaaat catatgcaag tgacattatt gactgttcac agtcaagatc
    46681 acttaatgac atctattgcg tttactgatt tagcaaaaga aatcatcgaa ctttatcgtc
    46741 gcgtatacag cgaataaata caacttcttt tttgaacgga agaagaaaaa tttttgaacg
    46801 gattttttat tttgttataa ggagaactct ctttatataa aaaacttata ggaggaagta
    46861 aaaaatgaac ggactatcaa gttggatgga gaaatacatc ctgccggttg ccgcaaaaat
    46921 cggagcgcaa aaacatttag ttgctttgcg tgatgctttt atcggcatac tgcccgcaac
    46981 aatggcggga tcagtcgctg taatgatcaa tgcaattatt cgtgatttac cgcaacagtt
    47041 taacagtacc tatgctgaca gtttagcagc agacaaagga atctttgccg tattgaatgt
    47101 catcatcgga atcaatggtt ttgtctggaa cggtacacta gcaatcgccg gattgatctt
    47161 tgccttttct tgggggtata atcttgcccg agcttatgga gtaaatgatc tagctggggg
    47221 gatcgttggt ttagctacct tgattcaagg tatttccttt ggtccagcat tatcagcagc
    47281 attagatgtg aatgttcctt caaatgtcgc agatgcaatc aatagttctg agattggtgc
    47341 aacgattgca gatggcacac tgtcagttgg attatggggt tggctaaaac tagatcattt
    47401 gaatggaaac gcttatttta cagttatgat catgggagct atttcagtca ttattttttg
    47461 taaattgatg cttgccaaca ttacgatcaa aatgcctgat tcagtaccac cagcagtatc
    47521 taaagcattt gcagccattt taccagcgac gatcgcttta tacgtcattg ctattatcaa
    47581 ttatatcgta ggtcgtgtag ctgatgggca actgatcatt gatttggtgc aaaaatatat
    47641 tgcagaacca ttcctaggat tatctcaagg gttgggagca gtattgatcg tcacagtatt
    47701 tgttcaagta ttctggttct ttggtattca tggatcaaat gtattggcac cagtgctaga
    47761 gggaatctgg ggacaagcac aactaatcaa tattgatatt ttccaaaaag gttataacgg
    47821 aaaaactggt acaccagccg tgttagatgc aatcgaagat ggaaaagctt atatgtgggt
    47881 ccgcggatcg ttcgatgctt ttgcatggtt tggcggatca ggcggaacga tcgtcttact
    47941 gatagctatc ttgattttct ctaaacgtgc agattatcta acagtagcta aattatccat
    48001 tgggcctggt atcttcaata tcaacgaacc agtgatgttt ggtctgccaa tcgtattgaa
    48061 tgcaatcatg tttatcccat tcttgattgc tccagtagta gcaacagcaa ttggatggac
    48121 agctacttat cttggcctag tcgctccggt atcgcagcaa gtcacatggg tagtaccgcc
    48181 gttcttattg tcattcttag caacaggagc ggattggcgg gcaccgatcg taacattagt
    48241 atgtatggtc gtgactttct tgatttgggc accatttgtc atctctgcaa acaaaatgga
    48301 ccctgccgca ggcgaacaac aataagatga acgtgaggag cgggacgctt taagtttcgt
    48361 tcctcataat gaattttcga ggaggaactg aaatgattac aattgccagt gcaatgcaac
    48421 aagatgaaat caaagaattg ttagaaggat acaatgaaga aggaatgact tttacattta
    48481 aagaaaaaca aggaatcaag ctgttctttg aaacaagtgc agaagatccg gaagttgcgg
    48541 ctaaaaaagc aaaggaacta atcaaagcac agccttgggg aacagtcctt tattttcaat
    48601 caacagctgt ttagaaaatg gtttaaaaag ataggatggt tgagatgata aaaaacggtt
    48661 tatttttatg tagtattggt tctttgatcg tgttgtatag tttgaatcca cattcgcaaa
    48721 ggtatgattt gtatagtatg gtcacaggtc tttttctaac aggattagga atctatttct
    48781 tcatgaaggg gaaaaaaaga gaagaagcaa aggagaaaaa taactaatgg aaatcacgaa
    48841 aaaattaaat attccagcat cgttttttta cgataaagtt atggactctg tccttttcga
    48901 tgtacgtaaa gcgaccggca aatcagtaac tagaaaacag ctgaaaaatt tggagtacgt
    48961 caaacaattc tcgcaaaata accgggctcg cataaaaatc gaagaagtca ttgaaaacca
    49021 gtcttataag tttcgtacat cgacaacgaa gaatgaattc gtcgttcatt atcaaatcaa
    49081 accattggac gattcgacct gtgaggttca ttacacagaa aaaatggagt cttatggcat
    49141 gcttcaaaag ttgaatgata tgcttttagg aacaatcttg atgtatttta aacggagacg
    49201 tttcaaaaaa atgctagata tgatcgaagc aacgtattaa atcaatgaaa catggtacta
    49261 tttagttatt gaaaaatgaa gtaagctaga aggaattttt cataggaaga tagatctttc
    49321 ctgcgaatcc tcactagctt ttttgtagga aggggcagca aaatgacaaa caaagtaaga
    49381 gagctaggtg tatcttcgat tgaggaaatg tttgatttag ccacttatgc atttaatggg
    49441 gcagatacac ctgaaaggcg agaacgtttt cgtacacttg cggagaattc ttggaattac
    49501 ggattttttg atgaggagga tcggctaaca agtcaagtca tggcgacccc ttttccagtg
    49561 aatttttacg gacaagagta cctaatggcc ggcattggct atgttgcttc ttatccagaa
    49621 gcaaggggac aaggcgggat caatcagatc atggaaaaga tccttgaaga ttgccgtgat
    49681 cgtaaagtaa gcttatctta tctggcgcca ttctcctatc ccttctatcg gcgctatggc
    49741 tatgaacaat catttgataa aatcagttat caactaaaca gtcgtgatgt gccgtttatc
    49801 aaaaaaaaat ctggaaaaat aaagcgtatg gattttgaag atgcaaaagc tgcaatcaga
    49861 agaatttatg aacagatgcc ggaaaaccaa cgagctggtc tgaagcgcga agactggtgg
    49921 tatacgtata aattcaagca aaaaggcaat taccagtttg ctttgcattt tgatgataat
    49981 gaggaagcaa cgggatatat cgtttatcag cttgcaacgt cttcctttat tattgcggag
    50041 tggggatttt tggatcatga tgctttttgc agccttgttc gcttcgtaag ttctcacaat
    50101 ggtgcttttg aaacatttga atattcatgc ggctacggcg gtaatgatca aaattatcta
    50161 ttagaaaatc catttgcttc tgtaatgatc acaccttata tgatggcgag gatcgtagat
    50221 atttctttgt ttttggaaaa ttatccattt aaaaagagac aagctgcatt tgccctacaa
    50281 atagaagaag atcattatgc gaaatggaat gaaggaatcg tggaagtaac aatcgaaaat
    50341 ggaaaaaatc atctctcaaa agtagaacaa acaaaactcc caatcgttcg aggaagtatc
    50401 caacatatca cgcagctatt attagggtat cgtaaagtgg aagagttggt attccaagaa
    50461 agaatacagg tgacaaaaga atatgaagaa acgttaagct caatcttgcc acagcaacag
    50521 ccaattctta atgactattt ttgataaaaa acgggtgatg acaatatttt tgtcaccacc
    50581 cttttgtttt tcatttggca tttgaaggaa aatgttaaag taaatcctct tttttcgtaa
    50641 atttgaattt tttgttttct tttgttttag ggttttcttt tttgtggtct tggattgctt
    50701 ctttcgtaat cttttcccga ttttttttag atgaatctaa gcgttctgcg tatacttttt
    50761 cttttggctt atcattcatt ggaaaggacc tccctacatt atttcattct acctctagtt
    50821 tatcatctgt taaggactag tggaaacgtt ttgcctaact tataagctga tttttttagc
    50881 agataagctt gcaagtaaaa aacaaacaag ctacaattga tttattgaaa ttgttcctgt
    50941 agctcagtag gatagagcaa tcgcctccta agagaaagcc gaggcattcc ccaaagggaa
    51001 aaaataaaaa acaactttca gttcgaatct attctgaaaa atgctaatgg tgacaacaaa
    51061 gcattcccca aattggggaa cgttctaatg ttaccaaatc aaaaaaatct gtagattgac
    51121 aactcgaaaa agcgttgata atcttatata tggccgaagg gaaaaatccc agaaacccag
    51181 taaaatcaag ggtttgcggc atgtgtcgtc atagctcagc tggatagagc actcgcctcc
    51241 taagcgaggg gtcggaggtt caaatcctct tggcgacggg cttcaaagcg ttcgaaaatg
    51301 ttagctggat tagctgacaa cgaacgcttt tgttattttc aaatcacgtt cgtgacacaa
    51361 aattccattc aaaatgatca atttccagct aacgcaatcc gatttttgtt agctgacagc
    51421 taatcaaaat taccggtttg caaacatggg ttttaagaag tccagctaac atttgggttc
    51481 cgctccgttg tcacctctta ttcggggatg caaatcagag aaaaggcggg aaaagaaaca
    51541 atctctccca aacttgcaaa catgaattag ctgaaacagt attcaattct attagctaca
    51601 gctaatggtc aaacagcaat gtctgtttgg aactttacta tctataaaag ttccaggcag
    51661 gcatttttta tttcctgaat cctggaggaa aggagtcaag atgactgagc caaacagaca
    51721 atcaggagaa aacgaagaaa gaatcataga aattgagatt gagcgtcttc gtccgttcaa
    51781 agagcacccg tttcaggtaa aagatgataa ggaaatgttt cttttgcagg aaagcattga
    51841 gaagtatggc attttaaatc cgctaatcgt cagaccagta ccggatggat actatgagat
    51901 catatccggt cacagaagaa aacatgctgc ggagaaactg ggataccgta aagtaccggt
    51961 aatcatccgg gtattaagtg aagatgattc catcttgagc atggtagatt ccaatcttca
    52021 cagagaacgg attagctaca gtgaaaaagc ttttgcttac aaactgaaga atgacgtatt
    52081 aaaaagaaaa agtggtcgaa aaaagagcca agttgaccac aaaacaccaa gaaagcgggc
    52141 aatagaaatc atcagtgaag attgtggtga tagcccaaaa caagtgcagc gttatatctc
    52201 actgacaaaa ctgataccgg aaatgttgca gaaactggat gatgagatta tttctttttg
    52261 tccggctgta gagatagctg cattaagtga aaaagaacaa agagaactgc ttgtagcaat
    52321 ggagtatgca caggcaatac catcactctc acaggcccag aggatccggc aactgagtaa
    52381 agaaaaacag ttgtcactgg aaaagatgga agagatcatg tgtgaagtga aaaagggtga
    52441 gatcacaaga gtggcattca caaacgagca gttgcacaag tattttccaa attcttatac
    52501 accggcaatg atgaaacggg aaatactggc actgttgaaa ttatggaaaa aagaatcatg
    52561 ggaaagttaa aggaggaaga aatcatgtgt aaagttatat ccgtagtaaa ccagaaaggt
    52621 ggcgtcggaa agaccaccac aaccgtaaat gtaggcattg gactggcaag agaaggtaag
    52681 aaagtgttgc tgatcgacgc ggatccacag ggaagtttaa ccgcaagtct tggatatgag
    52741 gaaccggatg atcttcgcat cacattggca acgatcatga tggaggtcat caacgaagaa
    52801 gaaatctctc tggaagatgg gattttacat caccaggaaa atgtagatct tctcccggca
    52861 aatattgagc tttccgcact ggaagtaacg atgggaaatg ttatgagcag agaaatgatc
    52921 atgaaagaat atatcgatgc gatacgatgc cgatacgatt atatcctgat cgactgtatg
    52981 ccgagccttg gtatgatgac aatcaatgca ctggtctctt ccgattctgt gttgatacct
    53041 gtgcaagccg catatctgcc ggtgaaagga cttcagcagc tgatcaagac cattcttaca
    53101 gtaaagaaaa gactgaaccg gaaactggcg attgagggca ttctcctgac catggtagat
    53161 ttcagaacca attacgcaag ggatattgca tcgagagtac atacaaccta cggaagtcag
    53221 atcgaggtat ttgaaaatgt gatcccgatg tctgtaaaag ctgctgagac cagtgcagag
    53281 ggaaaaagca tctacatgca ctgcccgaaa ggaaaagttg ccgaagcata taagaactta
    53341 acacaggagg ttttgaaaaa tgaaaaatag aagtggcgaa aagattaaac tggcaagcat
    53401 tgatgaactg ctgggtgtgg taaatgaaga atctgcaatg gagatagaaa tcagtaagat
    53461 ccatccgttt aaaaatcatc cgttcaaggt gctggatgat gaaaagatgc aggatctggt
    53521 tgaaagtgta aggatcaatg gagtactgac accggtactg cttcgaatgg atgataatga
    53581 agaatatgaa atggtatccg gtcatagaag aatgcatgca gcacagcttg caggacttac
    53641 gactattccg gcaatcgtaa gagaattatc ggatgatgat gccgtgattg cgatggtgga
    53701 cgctaacatt cagcgagagg aactgttacc gagtgagaaa gcatttgcat ataagatgaa
    53761 aatggatgct atgagaagaa cagcaggtcg tccgacaaaa gaaaatcccc gacaaaatgt
    53821 cgggaattat gagacggcag atctcattgg aaaggataat ggagaaagtg gacgacaggt
    53881 tcaaagatat attcgtctca cggaattaat accagaactt ttagatctgg tagataagaa
    53941 aaagctccaa tttacagttg ctattgatat ctcctacatc gataaggaag tacaagaatg
    54001 gatttacgaa tatattagtg acactggatt tattaagcca aagcagattg cagcactcag
    54061 aaatcagctg aatgacgggc caatcaatca gattcagatg ttatcaattt tcaataactg
    54121 tgtgatagca aagaaagtat cccggtctct tactttctca gaaaagaaac tgacaaagta
    54181 ttttccggat gattatacag ccaaagatat ggagcaggtg attgaatcat tattagaaaa
    54241 gtggatgcag gaacagtcct gttaaggaga gaaaaagcta agaaaacaat gtcaaagaag
    54301 tttaaaaaaa ggacttctta gcagaaaatg aaaggaggaa attatggaga aaaaaatgac
    54361 atttaattat ttttatggta ccgaagctga tcagttcagc ttctaccgca taccaaaagc
    54421 attatttaca gacagctatt ttaaagattt atcaagcgat gctaaaattt tatatggact
    54481 gatgttggat cgaatgtctc tttccatcaa gaatcagtgg tttgacgaca aaaatagagc
    54541 atatatctac ttttccatcg aagatattat ggaattactg aactgtggca gaaataaagc
    54601 catcaaatcc atgagagaac tggatgacga aacagggatt ggcctgattg agaaacgcag
    54661 acagggattt ggaaaggtga acgtcatcta cgtgaaaacc tttatgcctg agaaaacaga
    54721 tgagaaaaaa tttgaagagg aattaaagaa gtttaaaaaa caaacttctg tggaaaatga
    54781 ggaacccgca gaagtttaca attcaaactt catgaagtcc caaaatcaaa cttctagaag
    54841 tcccgaaaac aaacttcaag aagtttacat ttcaaaccct aataatacta atcttagtga
    54901 tactgaaatg aatgataata aatctaatcc tatcatatct gtggatgaga aaagatttga
    54961 tagcgataat cgctctgagg attatcaggc ttatgaaaac cttgtcaaag agaccattga
    55021 ttatgaatca ctggaagtaa cccatcatga cgatatgcgg caggtagatg aaatcgtgaa
    55081 cctgatcgta gagactgtga tgtgtaaaaa tgacaagatc ttgattgcca gcaactggta
    55141 tccggcatca ctggtgaaga aaaaatttct gatgctgacc tattcacata tcgagtatgt
    55201 attacactgt atgagtggta acaccacaaa ggtgaagaac atcaagaaat atttattagc
    55261 agctttgttt aatgcaccgt caacgatgaa cgggtattat caggcagagg tgaaccatga
    55321 tatgccagga ctggtaagat aggaggtgca catgtttatt ttaaaacttg ttgggaagat
    55381 attattactg ccggtatggc tgatcctttt tgtgatcggc ttggcagtaa aaatgacagt
    55441 acagacttat gcggttgtca gaggaatcct tgggtttata ttcactttat tgatcatagc
    55501 gactgcatac tgttaccatg attgggtaca ggttgcattc ctgttttcgc tgagtgttat
    55561 tctgtatctg atcctttttg caggagtgtt cgtagatact gtactggaca tgacaagaga
    55621 acgtattatt gattttatta tatcgtgagg agaatatgaa aatgagtgaa aacaatgatt
    55681 atattcagtt accaccacta aaaaaagaca caccatctga tgtggtagca tttatgtgga
    55741 agtacatgaa agtaccggag aattcaagag aaaaagttaa gaatctgctt aaagatgcaa
    55801 atgaaaatgg agtaaaatta agtcatcagg caccaaccct gtatgatgtt gtcccaaaaa
    55861 tggaaataaa atgaaggaga aaaggcggca gtttagaaag gctgttgcct tttaggaatt
    55921 gttgtttatt tgttgttttt tataagctat actataagga aaagataaca ttagagccag
    55981 aggtgaaatt tatgaactat aaaattttaa tggttgatga tgatagagaa ttgctaaaaa
    56041 tgctgaatca atactttaca ttgaagaatt atacggtaat gattgcagaa aatggcatag
    56101 aagcaatgga aaagataagt gcaaatcccg atattatttt attggacgta aatatgccgg
    56161 gaatggacgg aattgaagtg tgcagaagaa tcagagatat ggtttcctgt ccgattattt
    56221 ttttgactgc aaaagtagaa gaacaggatc gagtaatggg attgttgtct ggtggtgatg
    56281 attatgtttt aaaaccattc agtttgaaag aattagatgc tagaattatt gcccatttga
    56341 aacgtgaaga acgtttacat aggaaaaaag aacaaaggtt ttatggagaa ttagtgattg
    56401 actatgccag taaatgtgta catattaaag ggaatgcttt agagcttacg aaattagagt
    56461 atgagatcat agaatttttg tctatgaacc ctgaaatggt atttgataaa gaacgaatct
    56521 atgagaagat tggcggatat gatgcagaag gggacagccg ggtggttacg gagttgattc
    56581 gcagaatccg caagaaaatg aaaatgtatt cggaacacga atatattgca acggtatggg
    56641 ggaggggata taaatgggca aaataaaaaa tctttcgtta aggaaaacca ttgttttgta
    56701 tatgataatt agtttaataa ttagttttta tctttcagca ctaattatgc gaatagcaag
    56761 cacagtacaa aacaacattt ggtggaatta tgtagaccaa gaagaatatt ttgaaatggc
    56821 tgaaggggat ggtagaaggt atttgccaga tgttccgaga ccacattctt atgaaatgaa
    56881 agaatttgat tatcatgtat cggaaatatg tgattttctt cagacattta cagtgcttat
    56941 cgtatctgtt gcagggagta ttatagcggt atttcttttt tataagcata aactgaaatg
    57001 ccctatcgaa gaattagaac tggcttcccg acaagttggt cgaaataatt tagatttcca
    57061 tatcacttat gaaaatgaag atgagatggg cggattgtgc aaagagtttg aacgaatgag
    57121 aggacagctg gcagagaata atcaacagtt atggaaaatg cttgaggaag aaaaggcttt
    57181 gcgggctgcc attgcacatg atatacgttc tccgctctct gtgctggagg ggtatcagga
    57241 aatgctttca gaatatcttc cgaagaaaga gataaatatg gagcaagcct tagaaatggt
    57301 aaatgaaagc aaaaaacaga ttgaacgtat ggatatcttt gtggaaacta tgcgaaagat
    57361 gagcagttta gatacaaggg agttagtagc agaagaaatt accagtaaac aggtagaaat
    57421 agacgtacgg gcagagatga acgtgtttag gaaaaaattt ggaaagctat atgaattaga
    57481 atgttcggaa acagaagaaa aattttcagg agataaggaa gtgattttag aggttataga
    57541 aaaccttttg tcaaatgcct ttcgttacgc caagacaaaa gtggaaatgg aagtgtttct
    57601 tacctgttct gaattacaga tcagaataaa ggatgatgga gtgggattta caatagataa
    57661 gcaaaaggca acagagcttt tttatcagca aaatgtgaaa gacagtttga aacattcagg
    57721 aatgggcatg tatatcagca gattgtattg tgaaaagcat ggtggtcagt tactgataga
    57781 aaatgaaaaa cagagtggag ctgtaataac agcagtattt catcggattg catgagcggt
    57841 ccgatttttt tatgctgttg tctttttgtt gtgatttata ttttatgatg tctataacga
    57901 aggaaaggag gaatacgtat gattgctatt tttaaaagag agattaggaa ttatctaaag
    57961 cgaccgttat tttgggtagg tgttctgctt gtgatttatg gtgtgtttaa tgcgacaagt
    58021 ccatatttaa ccacacatta tcttacaacg ggggaggaaa tcatcaatga tcagtccaac
    58081 acttcggttg aaggagaagt gtatgagggc tatattccag ccacgcctga aaagcacaga
    58141 gaggtatggc atgaaaaggt aaaaataaaa ttaacggatg tgtttggatt gacggattca
    58201 gaagcacaga atgtcattga aaagctggaa agcatgaatt taaaagaggc ctatgcgtat
    58261 ttggagcagg aatatgactg gtacggggca aggtatttat acgaggacag tacgtattat
    58321 aagggaacgg cagaagaaat caacgcatat ctagataaaa aattggaaga taagacattt
    58381 tctttttatt acgcaagaaa atttgctgat tttgcgggtc tgtatatggt gttttttgca
    58441 attattatgt tggcggtttt atttttacaa gatacaaaaa agcatactta tgaattgttg
    58501 catacaaagc ctgtgactgc cgggaagtat gtaatgggaa aagtgagtgc aggatttaca
    58561 atttgtttgc ttgtgctaac tattttgaat atactgtttt gggtattgtg ccgcatctat
    58621 acaaaggata gtggatttga agtgcgacta tgggattttg tggcttctac ggtactttat
    58681 atattgccta atatgctgat gattgtgagt atatatacat tgatttcact catatttaaa
    58741 aatccacttc cgggtgtacc acttttgatt ctttatatgg tgtattccaa tttgggcgga
    58801 actaatgcag agggagttta cggatattgg ggcaaacctt tggcaatcat ggtacgattt
    58861 ccggggcagc tttttgatac gacaccgccc ccgatggcgc tcttaaatca aagttttctt
    58921 attattgtat cggtagtaat tatactgatt tcgatacaga tttggaagcg gaggcgaata
    58981 taaatgaaga aggaaatgaa gattgttctg ccattttata aaattgctta tgcagtatcc
    59041 tttgttgtaa ttttaagtgt gattcgtgca gttgttttca cgtatgaaat aggactatcc
    59101 atagagccgc cttttgcgat attgactgct gttttttgtg cagatactta tgtgcaggaa
    59161 attacaagca accgttccga agttcagaga ctgtatcaga taaaaaagag aatctattct
    59221 attatacaga gactgatgat acagggaact tttttgctgc tgctcgctgt tcttggatat
    59281 ggattgtttt ttgcgtttca gaaaccaatt acacatccag taacagaaag tgaaatactt
    59341 cagtttatta cctgttttgg ggcgattgta gtaactattt tcttttgggg aatattggct
    59401 aatacattgt ctatgctttt tcgcaatatg tggatgggaa ttggaagcag tcttttgata
    59461 tgggtagcaa caaattccac aggtggagat aaactttttg gagcatggaa tctgttttct
    59521 tattctttta gagatataga aaatactgcc gatattacat ggctgtatgg gaaaggcttg
    59581 tgtatttgta tcggactgat tttgttactg gcattgccga agatcgtaag aaagagaggg
    59641 taaatttatg agtattcata ttgaggattt aacggtaaga tttaagaata gtgtcacagc
    59701 aatcgaccat gcagatttag atataccaaa tgggatattt ggactattgg gagaaaatgg
    59761 agcgggaaag acaactttga tgagagtttt gaccactgtg cttaaaccta caaacggaat
    59821 ggttacatta gacggaattt tgtatagcga aggaaactat gaaaaaatcc aaagaaagat
    59881 agggtattta ccacaggaaa ttgaactgta tcctaatttg acggttcagg agtgtttgga
    59941 gtatatggga gatctggcag gtgttccgaa agcagaatgt agaaagcgga tagattatta
    60001 tttgaaaaag accagtctta tagaacatcg taagaagaaa atgaagcagt tatcaggcgg
    60061 tatgaagcga cgggtaggat tggtgcaggc gcttttaaat gaaccggaat ttttaattgt
    60121 ggatgagcca actaccggtt tagatccgga ggaacgtatt cgcatccgca atttgttagt
    60181 agatttttct gaaaacagaa cggttttgtt ttcaactcat gtggtagaag acttagctgc
    60241 cacctgcaat cagcttgcaa ttatgcataa aggtcgattt ctgtatgcgg gttctatgaa
    60301 gaatttgaca gaagaagcac aggggaaaat ctggatttgc aaagtacctg atgagagaaa
    60361 agcaagagaa gtggaacaga agtatcgtat tacatctaaa cagtatgttg aggggggatt
    60421 gcagttaaga gtgatttctg aaatacagcc agaattggag tgtatgtcaa ttcctgcaac
    60481 gttggaagat gcttatattt atgtgacgaa tcaatacgag tagataaagc accatctgat
    60541 gctttactac cagttgcacg ttgttcgctt tgaatatttg tggagaaaaa gtatgtatta
    60601 ttttggcttt ctataaaacc tataaaccag ccatttatat cctgcccgtt cactcgtccg
    60661 gttccggttt ttccataaat tctccatttt cagaggcggt aagatggatg gaatttttga
    60721 cggcatgaat attagcagga gtaaagttga agttgtttcg atataaattt ttcaaaagtt
    60781 caacttgttc tactggtgaa atctttaagg atgactgcat ccagtaggaa gagaaatctc
    60841 cggatatatt tttattgcca tatcctattt gctgaaggta tgaatttata gtggaagatc
    60901 cgagctgctt gtcgattgat tcaaaatacc agtttgtata tatcttttaa aaggtatatg
    60961 attaagaaaa acggcaggag gtatctgaat gaaatcacat aaatattggt ctatcggtgc
    61021 actgattaca atgcttggaa ctttttatac aggttataag ggatcaaaag aaggccataa
    61081 gtactttgca gcaagttctt tgctttgcat gattatggct atttatacag gacacaagat
    61141 gatttctggt aaaagtagga agaaaaaaga agtttcagta gagagtgttg aagattaaaa
    61201 aacaaaatat tttaataaat aacgccggtg cgggattttt gatatccagt actggcgtta
    61261 tttattctac aggggcttgg gggtgtagcc accaaatata ctattcgttt tctgcttcgg
    61321 caagtttgtt aaggatccac tccctattga taactatttc atcatcatcg cggagatcct
    61381 tgaaatcatt gcagtgtgaa gaagcaaatt catacatatt gtcaatgtca actgcaccag
    61441 taatctcacc cttattaatg attacaagaa tatttgttcc gtcgtcgtcg acagcaaagc
    61501 gcagttcatc aaattctata tcgggatcat ttttgagaat agaatctgtc gcaagtaatt
    61561 taacaagttc cattaccctg tcatctttat ctgcatcaaa gatctggatc ttttcaacga
    61621 gctgatttgc tgatgtcaca atccggtata agtacttttc ggtacgataa tcagccaaag
    61681 catttttttc ataaaatatt tcatatgtct tctttacttc tgattcagga accagataaa
    61741 tcatgacaag atcttccatc tggtgataga gtgtggagta gtttaaacga aaggtctctc
    61801 cacagctcgg gcaggtataa aggaaaatag attgattaag taccttctct ttcatttcag
    61861 gatccagtgc agtattaata ctgtcccaga gctcaaaatc tccctcatga tggcaggaag
    61921 gacaagttac cttttctata tgatgtcttg acataaatga tcctcctttc agtgagataa
    61981 atctatagtt tttctattgt agaataatct tatccgctat tatttcgcca gaaaattact
    62041 ctgtatctcc atcggcatat gataagcctg gcctcgtttt gtcaggctgt atagtttaaa
    62101 gctcatgagt tccggagttg cattcaaaga gctgcagagt ccgaaataat ccaagtcttc
    62161 gttctgaacc atatcttcga tctcctcatc atcaatcagt agatcggcag caaacagatt
    62221 ggcctgatat tctgtattat ccgtcatatt gtagagtgta tcatcttgca ttggagccat
    62281 tttcagctgg gaacgatgca ggatgatatg tcctaattca tgagcggcaa caatcatctt
    62341 ttcttcttct gaaaggaaac tactgatcat gacatagatt gtcttacagc tcatgaagca
    62401 atagcctttc agtgttttat atcttgaagt ttccccaaca acaatgttca tctgattcat
    62461 gatctcaaag ggatccctgg tgccatattt cttgattaat ttctttgttt ctgtatatat
    62521 gtaagtgttt ctcaaataaa tcacctcaaa agtaaaaaat aaaaagggca gaaatatcct
    62581 tgtaactata aggtaacaga ttaggtgtac aataattccg ccttctatta tttttcctct
    62641 tggtttttca gatatttttt cggtgtaaat ttctttgcac gtcttttgga atccagataa
    62701 aggctctgaa tctcatccat aaaagctatt ttatcttcgt ctgtcagtga tccaccggca
    62761 aacatagctg cagcctgttc cagaatctgc tgagcctgtc tggcaccacg gttaccaaac
    62821 tgttcggatg cttctgtgat aaaagcttca tcttcactca tgagataaga aacatcacac
    62881 tgtaatgcat ctgccagttt ctgatacaga acattttgtt ttggaaaacg tccttctact
    62941 tcccaggatc gaatggtcct atatgaaaca ccaaccatac tggccagttc ctgctgactc
    63001 atcttttttt cttttcttaa tgatcttact ttttcaccga atgtcataaa catacctctt
    63061 tctaaacctt gtcttataag tttcattagc cgcttcaagg caaaacggga aatgtgtctc
    63121 ccaaaaaata aaaattaatc ttgacaaagg gaaatatctc tcctataatg tgaatcacag
    63181 ataagggaaa catctttcct ataagataca caatatttcc tcctttgtca atgaatatgt
    63241 gaaatgaatt tcctgtattt taaagaaaac aggaaggatg cacagtcatt gacagtcaaa
    63301 atgggataca tgttacaaaa agaggaaaga cgtatgggag gtgacaaaag tgagtcagga
    63361 tcagacttct attatctgta ttgatctgaa gtctttttat gcttctgtag aatgcgtaga
    63421 acgtggactg gatccgttta aagcaaacct ggtggttgca gatccgacca gatcaaagtc
    63481 aacaatctgc ctggcaatca ctccggctat gaagtctctt ggcatcaaga accggtgccg
    63541 gatccatgag ataccggatt gtgtaaagta catcacagcc atgccaagga tgcagctgta
    63601 tatggattat tctgcaaaga tctatggaat ctatctgcgg tacgtctcaa aagaagatat
    63661 ccatgtgtac agtgtcgatg agtgttttat tgatgtgaca aactatctgc agctttatca
    63721 tctcactgca aaagaaatgg cggtaaagct tatgcaggag gttatggagg aaacaggtat
    63781 cactgcaacc gctggtgtgg gaaccaatct gtatcttgct aagatcgcaa tggatatcgt
    63841 agcaaagcat gtggatgacc atattggaat cctggatgaa ttctcttaca gagagcagct
    63901 atgggatcat aaaccattaa gtgacttctg gaggattgga tcccggactg aaaaaaaact
    63961 ggccggttac gggattcata cgatgggcga tatcgcaatg gcttctttaa gatccgaaga
    64021 ctggctgtat aagatgtttg ggattgatgc agagctgttg attgatcatg catggggcta
    64081 tgaaacatgc cggatgagtg acatcaagaa ctatcattcg gaggaacaca gcctttcaaa
    64141 tggtcaggtg ctgatgcgaa attattcttt tgaagaagca cttgtaatcg taagggaaat
    64201 gacagacaac ctggccctgg atctgtttga aaaaggactg gtgacaagct ctctcacctt
    64261 atggatcgca tatgaccaca ggtatgagca tgaggcatcc aaaggaaccg taaaactcga
    64321 aagaggaagt aacagttcaa aaaaaatcat ggatgcagtg gaagatttat atctcaggat
    64381 tgcggacaga tataccggaa ttcgaagaat cgaggtgtgt gcgaacaggg ttgctcctga
    64441 aaattatgtg cagtacagcc tgtttgatga tccaaaacag accgataaag aacggcattt
    64501 acaggaagca gtattgaatg taaagcagcg ttatggaaag aatgcgatca tgcgtggatc
    64561 taacctgcta gagtgttcta cttatcgaga acgcaatgaa caaataggtg gtcaccgtgc
    64621 ttagaggagg tgtaaaaagt gctggcaagt gaatatcaac cgtatttata tttatcaaga
    64681 ccggtttcca ggagacatcc catggatgta ggacgcaggg caaaacagtt tgctccattt
    64741 gcggcacttc gtggactgga tgaaacgatc cggcaacagg aaatcattta cgaatcgaaa
    64801 agagatttat ccgaagaaaa gaaaaatgag ctggatatga aattaaggat cctggcatat
    64861 gggatgaaga tacaggcaac ttattttcaa aaatcctgga aggatccgtc agttggccag
    64921 taccatacat tatccggaac cgtagaattt tttgatccat cagtccactt acggatcgat
    64981 gatactgaga ttcagatcca ggacatctgt gatctgactg gtgatgtatt tgaaactatt
    65041 gaaatatcat gttaattaat cacagcggaa ttttttatac cggaaagagt gtgtggtagc
    65101 tggtggaagg ataaaaaagg atgcacagat cgacaaagca gatctgatca gaataaaaat
    65161 cgtgctgttc gtgcagcttt ggcacttacg gaatggatgg catgatgctc ataaggcgga
    65221 tttgatttcc ctttggtccg ttgagtaata aatggagaaa tatcttattg cttaaaggag
    65281 gaagcctata tgggatcagg tgctattaaa tggcatgtac actgctctgt atgcggagca
    65341 tttattgaaa agagcgcaca aagcgattca gaagtggagt gcaaaaaatg tcgcagtaca
    65401 ttggaaatat ttgtaaagga tgatatggtg tcggttcgtc cgatccacat ccgagatgaa
    65461 caattaaagt ccaggatgcg gacgtattcc cgaaagatga tgaatcaggg atcataacag
    65521 aatagaatga gctgtctgta gtaagcgttg gatttggcag gaaccatcaa gaacgcacca
    65581 gacagcaaga gtttgtcaag gagctgaacc tgactggaat cactaagagc ccggcaaaac
    65641 atttacggat acactgcaag atcagaagta ttttctggtt ttggagattg ttgaagtatt
    65701 tgttttgtcg ggcttttttg acgtatttcg acaaatttta aatttttttg tcgtacccca
    65761 ctgtaaaaca ggctctcagc gtttcgttat atagaggttg aattcttttt tgcaaaaata
    65821 attgtaaata gagattttga taacatgacg caaaggagga agcaaagatg actgaaatcg
    65881 aataccagga atttgtaagg cattgtcctt acgatgctat gggcgattat tccatgtttc
    65941 gcaaagagca aacagagaat aaatcagaag atgcacatag caactgaata agccaggcaa
    66001 tctggcaaac ttaatctaaa cgcagataca tgcgttacaa aggagtcgcg gactcccgtt
    66061 caaaaaaaac gggtgagttc gtgacctctt gtgctgcagt tctttatgtc tgtgcaggaa
    66121 ttttataaaa gatggaatgg accacccgga gccgaaaggc agaaaggtgg cctttatgtt
    66181 gacattaaaa gaactgaaaa aaatcgtgaa agttgctgat atggagaaga gaatcccaag
    66241 cgtgaaatcc ttgaaggaac acaaagttgt agtaaaggaa atgatcaatg cagatacaac
    66301 aatctctgtt tatgatcacg gatatgtact ttatacagca ggaaatcaat caaccgtatt
    66361 tccacttcat agttgtgatg actatgaata tgtgagtgta actggcgata acaaggaatt
    66421 caataaagag ttctttgata atgaaaactg gtatatccgt ctgctgatgg aggctgaaga
    66481 ccgtatggca tacagccaga gcaaaatcag caccaatcat ggtgtatttt ctaacagcga
    66541 tgttacagat gatgcggaga ttatgagagg atcttcaaaa gattttgttg acgatgttat
    66601 cgacagagaa attctgaacg ctttgatcaa agagttaaca gagagacaaa agacggtact
    66661 caatctggtt tattttgagg aaatgcgtca gcaggatgtt gcagattatc tgggaatcaa
    66721 acagcagagt gtaaatgacc tcctgaacag ggcattaaaa acgatgaaaa aaaaggcgga
    66781 aaacgaagaa ttttaaaaaa ttttaaaaaa attgaattag accactgtaa aacaggctct
    66841 gagcgtttcg ttatatgaag ggtttgcata gaacaccttc atgtaccttg aaaaatgaat
    66901 agcctgcccg gagtgatatt tggtttgaac atgcatagag cgaaaagctg cgtgtctgcc
    66961 agaagaaaac gtatcagaga tggaaactga tataggaacg gatccgggaa agaaaacagg
    67021 aaaacgctta aatcttaaat caaaataaaa tgtctgaatc taaaaagagg atgacagtag
    67081 aaatcatgtg gcggtatttg tgacaaacag gtaccgccat atatttgtgc tgttatctca
    67141 gcttgtgctg actgtcccaa atagcgcaaa tttcaggaaa ggaggcgatc atcttcgtat
    67201 aaaagataat atgcagaaac taacagataa ccatacacaa aagaatcaga aaggaaggat
    67261 ttaagagaat gaacgtgaaa aagaaagcac gcagggtgat gtccggttta ctgactgcag
    67321 taacggttct atcgacggta ctctctcccg ctgttgccta tgcttctgat gatgccggat
    67381 ctgtaaaaaa gattccgtat tatgaggaga tcaaggatca gttggatgaa gatgaagtgg
    67441 taactgcaaa ggattatgag atcaaggttg gagacaattt cgatgtaaag agtgattata
    67501 ccggtcttac gatccaggat gacagcaaag taaaagttac atttcaggaa gcaaaagata
    67561 cggacgggaa tgatttttct accgattatg ccaattccta taaggcagtc tattatgtag
    67621 aaccacagac aacggatcac ccaacctacc agatcaatcg aaagatcgtg gtaaaagaag
    67681 cggatcaaca gaaagattcg cagtcagaaa gttcttctga tcaggatgct ggttcttccg
    67741 ataagacaga aacagaggat tctgaggctg actcgtctac agagggaact gatgctgctg
    67801 acacggagag caaaacagaa ctgacagaaa aagaatttga tgcagaaatc gaagcaacgg
    67861 aggatcagga gaccgttgat ccggaaacag ggatcacact ctcagaggtt atgcaggaag
    67921 ctgttgacca ggaagttgct cttgcagatc ttgaagcagg cgaaagtatt acttttgata
    67981 tgccaatgat gcttgcttcc ggtgaaacag gaacaaaatc agtcacagtt acagccggct
    68041 cctggtacta ttacgcagac tatggattag gttcttatct gacttgtcca tattatgtga
    68101 aatggggaag catcaatgcg acagcatact gtgttgaacc atcgaaaaaa ggaccgggaa
    68161 atggaactta tacgatccag aaacttgccg atggaaagac acttgcaaag gtctgctatt
    68221 acggaacaaa agcaagtgat gagaatggtt tcttcgatga gaaacatccg gattttccgg
    68281 caggaaagag attcatcatt acccatcttg cagcagctta tgcaaatgga tccagtgact
    68341 gggcatccgg aactaatgca acaggaaaga acctggcaat ggagctttac aattattgtg
    68401 taaatatgcc ggacattccg tctgtagata tgagcttttc cgaatctaat gtaaaggctt
    68461 atgtggaagg aaacagccag cgaacaagtg tgatcacatt caaagcagat aaactgcaga
    68521 cgatcacatt taagttgcca agcggtgtaa agcttgtaaa tgtgacaacc ggtaaaacca
    68581 gtgctgcagg agcaagtgta gaaatcagtg gaggtacaca gttttatctg acagcactac
    68641 ttgatcaggc agagagcgtc agtgctacat tttcttctcg gatgaaggga agcattgata
    68701 aagaatactc tgcttacaag attgtaacag gatctggaac acaggacctg gctcttgttt
    68761 tcggtgaagg tgttggaaat gagaaatatg tggattttaa agtaacctgg acaaaagaat
    68821 gcaaagtatc cattgtaaag aaagatcagg atacaggaaa tgcactggct ggtgcagtgt
    68881 acgggatcta ttccgatgct tcatgtacaa agctgatcgc agagatgcct gcaactgatc
    68941 agaatagtgc ttcacagctt acaatggaga aaacacagga agttgtttat ctgaaagaaa
    69001 tctctgttcc aacagggtat cagatcgata caaagtctta taatgtgact cttgctatcg
    69061 gaaagacaac gaccaaaaat gtaacagaca aacgtgtaaa tgcaaagatc aacattgcaa
    69121 aacaggatgc tgagacaggg aatgcagcac agggtgatgc aacgctggaa ggtgcagtat
    69181 atggccttta tgcaagggaa gatattgttc atccggatgg aagaaccgga acgatccata
    69241 agaaagacag cctgatcaca tccctgacaa cggataagaa tggcgaagct tctgtatcgg
    69301 atctctatct tggaaagtat tatctgaaag agcttagtgc tccggttgga tacgtactgg
    69361 atccgacaga acatgaggtg gactgtactt acgaaggtgc tactgttccg acagtagaaa
    69421 gaacttctgt atgtaaagaa actgtcgtca agcagccgtt ccagatcatt aaggcagcaa
    69481 acaacggaaa aaccgatgca gatcttctta agggagttgg tttttcagca tggcttgtca
    69541 gtgatctgaa agtaaaagca gatggaagtt atgattttga ctcagccaga ccagttgtac
    69601 tgactgcaga tggccaggca gaaatgttta ccgatgaaaa aggatatgca agatcgattc
    69661 cgcttccata tggaacttat gtggtaagag aaaccacaag caaacacaac tatgcaccgg
    69721 ttgatgattt tatagtgaag atcacagaga atcatccgga tacaccgcag acatggcgag
    69781 tgcttctgga taaagaattc aaagcaaaat taaagattat caaaaaggat gcagaaacac
    69841 agaaatctgt actcctggca aatactgagt tcaagatata cgacctggat aaccagaaat
    69901 atgtggaaca gacaacatcc tatccgaagc caacagtaca caaatcttat ttcacaaacg
    69961 aggaaggata cctggtattg ccaaagaatc tgaaacctgg taactaccgg attgaggaag
    70021 tgacggcacc cgatgggtac acgatatcca aaaactatgt gacagttgcc gttgatacag
    70081 atactgctta tctgaccgat cctgtcacag gagatgcagt cattgctgtg gaatatacca
    70141 atgccccggt caaaggtcag ttaaagatct ataaacaggg tgaagtgtta aagggatttg
    70201 ataaggactt ccagtatgaa atggctggac ttgcaggtgc tgaatttgaa gtctatgcgg
    70261 cagaagatat ttatactgcc gatcatcagg tagatgcaga tggacagaga actctgtatt
    70321 ttgcaaagga tgcactggta gcaaccgtca caacggatgc agatggttat gcaaccgtaa
    70381 agaatcttcc acttggcagg tactatgtta aagagaagaa tgcaccggac actcatgtgt
    70441 taaataccgt gccggaaaat gtcgaatttg cttatgcgga tcaggatact gcagtgatcg
    70501 agaaagaaat ctctgtcaca gatgaacgac agaaagtgtc gattactgtc gaaaaacagg
    70561 atgctgagac aggcaataca gtagccggag cagtgttcgg tatttacaat gcaaaagaca
    70621 ttcagacgaa agatggaaaa gtgatcgtca aagtagatac tcttttacag gaaatgactt
    70681 ctgatgaaaa aggtcaggca gcatgtacac tggatcttcc acttggaagc tattatgtaa
    70741 aagaactgaa agcaccaaat ggattcgtat cttctgatga agtactgaga tttgatgctt
    70801 cttatcaggg gcaggatgta cagacagtaa cattaaaatc cgtaaagaag aaccagccga
    70861 caactgttga gatcacaaaa tcagatgcaa caaccggtgt agaactggat ggagcttatc
    70921 tgaaagtaac ggataaagat ggaaatgtgg tagacagctg gacatcttcc aaagatgcac
    70981 cgcatgtgat caaatatctg aaagtgggtg agacttatac cctacatgaa gagtttgcac
    71041 cgcatggtta tctggtagcc aatgatgtga cattcacagt caaagatacc ggagaagttc
    71101 agaaagtgga aatgaaggac gaggtaccgg ttggtgaact catcatcaac aaaaagggag
    71161 aattcctgga ttctgttaca ctggccgata aggtcaaagg tgtggtggaa cacattttca
    71221 actatgtaac cggaaagctg acagatgtta cgtttgaagt ctatgctgag gaagacatta
    71281 aggctgccga tggcgtcagt gacgattact ataaaaagga tgaactgatt gcaacgatca
    71341 agacagatga aaccggtatt gcaaaactgg aaaatcttcc acttggtaaa tactatgtga
    71401 aagaaacagg aactgcttac ggtcatgtac tggatggtga gatccgtcat gtagatctga
    71461 cttacgtgga tcagaataca ccagttgtag tctatgacaa agactggcag aacaaccgcc
    71521 agagagtaga agtcagtgta cttaagaaag aaaaagattc tgaccgtaca ttggaaggcg
    71581 ctatctttgg attatttgcc aaagaagaca ttaagtctga gacaacaggt aaagtcctga
    71641 ttgaagctga tgagatcatt gaactgaaat ctacggatga agaaggaaag atcacatttg
    71701 ttgcagatct tccaatagga gcaacttact atgtaaaaga gctctatgca ccggacggat
    71761 tcgtaaccaa cgatgaagta aaggaattta cctttgagta tgtaggtgag aatcagccga
    71821 cagtcactta tgattttacc tttgataatc agccaaccgt cgttgaattt gccaaatcca
    71881 gtctgacaac cggaaaagaa cttccaggat gtaagctgaa agtggtagat tctgatggaa
    71941 atatcgtgga tgaatggact tccggtaaag aagcacatgt gatccgtgag ctgactgtcg
    72001 gaaaagaata cacactggtt gaaacaaaac ctgctgatgg ttacgtgaca gctgaaagcg
    72061 tgaagttcac gatcaaagat actgccgatg tgcagaaagt tgagatgaag gatgatgtaa
    72121 cgaaggtgaa aatctccaaa caggatatcg ccggaaaaga acttccggga gcgaaactca
    72181 caatccttga tcaggatgga aaagttgtgg aaagctggac cagtacagag aaagcacatt
    72241 acatcgaaat gcttccgatc ggaaaataca ctctccgtga agaaacagca ccggatggct
    72301 atctggttgc aaaagatgtg gaattcgaag taaaggatac cggtgaagta cagcatgtaa
    72361 ccatggtgga tgaggaaaaa ccggcagaaa agacaccgga aggtggaaaa cctgtcagtg
    72421 attcaccaaa gactggggat aacaccaatc tgtggctgtg gtttatgctt ctcggcattg
    72481 gtgcgactgg tacaggagcc cttgcattta tgagaaaaaa gaaacactaa tcaaataaga
    72541 atgagcgttc atggaaaccg aaaggaatct gtggacgctt ttttagatgg gagaaaccat
    72601 gagaaatatc attatttttg ttgctcttct gggagcagcg gcaatattta cagttttgta
    72661 ttgtctcatt gctgccggaa gtcaggcaga gaaaaaactg acagaaatca tgagaaaaga
    72721 ggaagaacgg aatgaagaca aataaagatc taattataga accaaatgca gctattgagg
    72781 gaagaaagta cagcgaagaa aagccatggt cctgcaagta ctgttactgg tgggaaggca
    72841 aaaagaaagg ctgtagcttg aaacagtgcc attatctgct tgctgagaag aaaaaagcag
    72901 taaaaacgac accatgtagt ggctgtccgt atggaaaaca tgttccatgt atcggatatt
    72961 gtattgcccg tcttcattct gaaatgaaag gaaagaaagg acgtgggtaa ttgcaggaag
    73021 aagtaaatca gaaagtaatc agcctgagca tccagggagt taagatcact gccagtgtgc
    73081 taaaagcagc ccttcggaag ttcctggaaa tggataaccg caggaaacag aaagcaacgc
    73141 aggtgaaaat ggcagaaaag accggacggg ctcaggagaa aggaagggaa caagcccgaa
    73201 aaaagattga aaagaaaaag ccacatggaa agcagaccat caagcagctg aatgcacagg
    73261 gagtacagct ttccaactta aagatcacag atgaaaatat caaatccttt gaccgtgtgg
    73321 caagaaaata cggcattgat tacagcctga aaaaagatgt cggtgcggat ccgccgaaat
    73381 atctggtctt ctttaaggca aaagatgtgg atgtgatgac agcggctttc cgggaatatg
    73441 ccggagtaga actaaaaaag aaacaggtga agaaaccatc ggtcagaaag aaactgcaga
    73501 aatctgtaga aagaaaagca aagcaccgcc agcgtgtgaa gcagagacaa aaatccagag
    73561 gtcaggaacg atgatgcggg agaaattaca gaagatccag gtcaaacggc tggtgatctt
    73621 aaatctccca tatttcttta tcttctatgt agcagataaa ggatcctggc tgtaccggca
    73681 ttgcctggga gaaagcatgg tccagagact tggcgtgatg ttagtcaatt ttcgactggc
    73741 atttttaagc tggctgccaa gtatcgcttt gcaggacctt acagtaggtg ttctggttgc
    73801 aagtgcatta aaactggttg tctactatcg ttctaaaaac gcaaagaagt tccggcaggg
    73861 tgtggagtat ggatctgcaa gatggggaaa tagaaaagat atcgaaccct tcatggatcc
    73921 ggtttttgaa aacaatgtca tcctcacaga aacagaacgt ctgaccatga acagccgacc
    73981 aaaagcccca aagtatgcca gaaataagaa tgtgattgtc atcggtggtt ccggatccgg
    74041 taagacaaga ttctatgtga agccgaacct tatgcagatg acagatcacg tatcctatgt
    74101 ggtcactgat ccgaagggaa cgatcattgt tgaatgcggg aagatgctgg taaatggagg
    74161 ctaccggatc aaggtgctaa atacaatcaa ctttaaaaag tccatgcatt acaatccgtt
    74221 ccattatatc cggagtgaaa aagacatctt aaagctggtc aataccatta tcgcaaatac
    74281 caagggtgag ggcgaaaaat caacggaaga tttctgggtc aaagcggaac gtctattgta
    74341 ttctgcactg atcggataca tctggtatga ggcaccagag gaagaacaga acttttctac
    74401 tctgttggaa tttatcaatg ccagtgagac cagggaggat gatgaagaat ttaaaaatgc
    74461 agtggatgaa ttgtttgaag aactggaagc agaaaatccg gaacactttg cagtaaggca
    74521 atatcgcaag tacaagcttg cagccggcaa aactgcaaaa tcgattttga tttcctgtgg
    74581 tgccagactt gcaccatttg acattcagga actaagagaa attatgtcgt atgacgaaat
    74641 ggaactggat atgatcggcg atcagagaac agccatgttt gtcatcatca gtgatacaga
    74701 tgacacattc aactttgtag tagcgattat gtacacccag ctctttaacc tgctttgtga
    74761 taaagcggat gatgagcatg gaggcaggct cccttatcat gtacggctgc ttcttgatga
    74821 gttcagcaat atcggacaga ttccaaaatt cgacaaattg attgctacga tccgaagcag
    74881 ggaaatctcc gcttctatca tcttgcagtc acaatctcag ctgaaaacta tctataagga
    74941 tgctgctgag acgatcacag gtaactgtga caccgttctt ttcctgggcg gaaaggaaag
    75001 ctccacactg aaagaaatat cagaaaccct gggaaaggaa accattgatc tttacaacac
    75061 atcagacacc agaggcagca accggtccta tgggctgaac tatcaaaaga ctggaaaaga
    75121 actgatgagt agagatgagc tggcggtcat ggatggagaa aaatgtatct tacagcttcg
    75181 aggagtccgg ccgtttttaa gcaacaaata tgacatcaca aagcataaac ggtacaaaga
    75241 gcttgccgat tttaataaga ataatgcgtt tgatgtcgaa aagtatctgg cacaccgact
    75301 ggtgatgtcg gaagatacag aatttgaaat gtatgaagta actgtaacac aagaagacgt
    75361 atcagtgatt gaagctgagg aaggtgagga ctgatatgaa agaaagaatt cgagcaccct
    75421 gctactactg ataagggtac aaaaaggtct gaataaaagg gaaaggagta gagccaaacg
    75481 cttacagacc ataagaaaaa gcgtttgttc atacatttga ttatggcttt ttttagcagt
    75541 gcaatcaata tccttcagac actggtcgtt gcaatcggtg ccggtcttgg tgtctggggc
    75601 gtaatcaacc tgatggaagg ttatggaaac gacaacccgg gtgcaaaatc ccagggaatt
    75661 aagcagctga tgagcggtgg tggtgttatc ctgatcggaa cacagctgat cccgcttctg
    75721 agtggattat ttggttaaga gaaaggagta gagatccatg ttcagtcaga tttttgatgc
    75781 gattgaggaa tggatgaggg aactcttaac cgggatgatc acttccaacc tggacacgat
    75841 gtttactgat gtcaatcaaa agactggtga gattgccacc caggttggac agaccccgca
    75901 agggtggaac ggcagcatat tcagtatgat ccggaaccta tcggattccg tgatcatgcc
    75961 gatcgcaggt attattatca cactcgtact ctgctacgaa ttgatttcta tgctgaccga
    76021 gcgcaacaac atgcatgata ttgatacctg gatgtttttc aagtacttcg taaaaatgtg
    76081 gatcgctgtt tatctggtga gtaacacatt tacgatcaca atggcggtat tcgatgtggg
    76141 ccagcacgtg gttaattctg cggccggtgt tatcagcgga agtaccgcca ttgatatttc
    76201 ttcggcattg acggatcttt ccgcaaccct ggaaagtatg gaaatcggag aacttgttgt
    76261 attggcgctg gaaaccctta tcgccggctt ctgtatgaga atcctgtctg tactgatcac
    76321 agtgatcatg tatggacgta tgatagagat ttacctatat acctcagttg cgccgattcc
    76381 attcgcaact atgagtaaca gagaatgggg acagatcggc acgaattatt tcagaggact
    76441 ctttgccctg gctttccagg catttctgat gatggtatgc gttgcaatct atgcagtgct
    76501 tgttgcaggt atccagtatt cagataatct gagttcttca ttatttggcg ttatggctta
    76561 cacagtaatc ttatgttaca gcctctttaa gacggcctct ttaagtaagt cgatattcaa
    76621 cgcgcactaa attacaggaa ggagtgaaaa tcatggcata tgtcagcgta ccgaaagatt
    76681 taacgaaggt aaaaaataaa gtagcattta acctgaccaa aagacagctg atctgtatcg
    76741 gtataggtgc tgcaatggga attccaagct atttcctctt gcgaaatgtg atgggaaaca
    76801 gtaatgcagc aacggtcatg gtgcttttga tgttaccggc atttttattt gccatgtacg
    76861 aaaaagacgg gatgcatctt gaagatgttc tgatgcacat gatccgggtg aagtttcttc
    76921 gtccacccgt cagaaaatat gagactgaaa actattatga aacagatccg gaacagatca
    76981 gacagtcacc ggatgcagga aaaccgaaag gaggaaaaac ggttgcgaaa aaagaaaaat
    77041 aagaaaactg tcgcagatac cgggtacaaa aaagtagaca gaaaagagaa aaagaaaaag
    77101 gaaaagcagg aagaaaaacg caggaagaaa aaactgtctg ttcagcagtc gatcgcttat
    77161 aaggaaatgg gaagagatgg aatctgcagg gtacagggaa aaacttattc taagtgcatc
    77221 cgcttctatg acatcaacta ccagctggct cagaacgaag ataaaaatgc gatctttgaa
    77281 aactggtgtg attttctcaa ttactttgat gccagtattc attttcagct gagctttatc
    77341 aatcataaaa gtagcatgaa agaatttgaa caggtcatcc ggattcgtcc tcaggatgat
    77401 gcctttgacg atgttcgtat ggaatatgcc aagatgctga aacagcagct ggcgaaagga
    77461 aataatggac tggtgaaatc aaaatatatc accttttcca tcgaagcaga taatatccgg
    77521 gaagcaaagc caaagctgga acgtattgag tcagatattc tgaataattt caagatcctt
    77581 ggagttccgg cctatccatt gaatggagtg gaaagactgc agattttata tgagactttc
    77641 aatccagaca atatgacaga ctttcagttt gattatggtt ccatgatccg tactggactc
    77701 aataccaaag attatgtggc accgaccagt tttgtattca aggacagaaa tacattccgc
    77761 atgggaaata ccatcggagc agtctcttat ttgcagatcc tggcaccgga gcttacagat
    77821 aaaatgcttg cagaatttct ggatattgat aagaacctca tcgtcaatct gcatgtccag
    77881 tctgtggatc agatgaaggc aatcaagctg gtaaaaagca aggttacaga tatcaacaga
    77941 atgaaaattg aagagcagaa aaaggcggta agatctggat acgatatgga tatcatccca
    78001 tcggatctga atacttatgg cggagaagcc aaacgtcttt tggaagatct gcagtcacga
    78061 aatgagcgta tgttccttgt aacagcgctc tttttaaata ctgcaaagac aaaacaggca
    78121 ctggataatg ccatcttcca gacggccggt attgcacaga aatataactg tgtgctgaaa
    78181 cgtctggatt atcagcagga agaaggattg atgagcagtg ttccgttggg agtaaatcat
    78241 atcccaatca ggcgggctct tacgactacc agtacagcaa tctttgttcc gtttacgaca
    78301 caggaacttt ttatggcagg agaatcctta tattacggat tgaatgcact cagtaacaac
    78361 atgatcatgg tggatcgtaa aaagctgaaa aacccgaatg gactgatcct tggtacgcct
    78421 ggatccggta aatcctttgc agcaaaaaga gaaatcacca acgctttctt tgttacgaag
    78481 gatgacatta tcatcggaga tccggagggt gagtattacc cactggtcca tgcacttggc
    78541 ggacaggtcg tacacatttc accaaccagt aaggattata tcaatccgat ggatatcaat
    78601 atggattatt ccgatgatga caatccactt ggtgtaaaat ccgattttgt cctgtcctta
    78661 tgtgagctga tcatgggaag cagggatggt attgaagcag aggaaaaatc agtgatcgac
    78721 cgttgtcttc cactggtgta tcagaagtac tttgcagatc caaaaccgga aaatatgccg
    78781 gtccttggtg acctgtatga ttgcctcaga aagcagaaag aaccccaggc ccagagaatt
    78841 gcaacagcac tggaaatcta tgtaaatgga tcactgaaag tattcaacca tagaaccaat
    78901 gtggaactga ataaccgtat tgtctgcttt gatattaagg aacttggaaa gcagctgaag
    78961 aaaatcggaa tgctcatcgt ccaggatcag gtatggaaca gagttacaat caaccgtggc
    79021 atcaaatcta ccaggtacta tatcgatgag tttcatcgga cgagacgttc cgcttgttga
    79081 atagacagcg gggtcagtag ccgtccgtaa aaagaaaagc tactgataca actgatatgg
    79141 tgttgttcaa atgaaggggt aacgcccgga agggacacac acaaactccc tacagcgtga
    79201 tagttgtgca agaactatcg ggttgtcaaa agttagggtg aagagcaaaa agcaggtcct
    79261 aacaggtaag gctgaggaaa gattcacaga ggtgtgggtt gcctgtgatt atgtagtgaa
    79321 gctgtatatg gtgagtatcc acggaagtgg ggacgaactg acgatttaaa gagtctaaaa
    79381 ttcgaatgcg ttgaaaagcg tatgccaacg gtttggcgtt gattaccgaa aagtaactgg
    79441 gtggaagtga aagtcggagc attgttacag gcaatggaaa tcagcaggct caaaggaagc
    79501 acctaagtac agtatattgc atcatattgg aacgtcgaaa gcaacgaaca gcgagcagtt
    79561 gcacatgcta tgacctgttg gtaaggaaaa cacgctgtat aacttacctt tatcgttgtg
    79621 agagcggagg cacgagcgat gaagcttctg taatgggagt ggagcaacag cctctagtgg
    79681 gacgactggt cagtctgcca gtcgacaaaa caagtgtaat aaagtaatgc agttaacatt
    79741 cataggttcg agtatgacta agagaaacaa gtcttgcgag agtgaggtga tgttgactat
    79801 gcaaagaaag gaattgttaa agaaaagtgc tatccgatat gctgagtact acggcatggt
    79861 cgaagtacag gacgcattat atgcggatag tgcgagcgaa aagattttca cgaatctgat
    79921 aagtattatc ggttcagatg ccaatatcaa aatggcatac cgtaatctca aatcaaacaa
    79981 aggaagcagc acacctggtg tcgacggtaa gacctttaag gacttagctg agatgtcaga
    80041 ggaagcattg gttcaatgtg ttagggacaa aattcttaac taccagccta aagcggtgag
    80101 aagggtatat atcccaaagc caaatgggaa aatgcgacca ttaggaatcc ctacggtatt
    80161 agataggatt gtacaacaaa gcgtgttgca ggtcatggag cctatatgcg aagccaagtt
    80221 ttatcggcac agttatggtt tcagaccgaa tcgtagcact aagaatgccg ttgccgtgtg
    80281 ttacaaactg gcgcaggtgg acggattcca ctatgtagtt gatgtagata tcaagggatt
    80341 ttttgataat gtcgaccatg gaaagctact aaaacagata tggacgatgg gaatacgtga
    80401 taaaaggctg atttccttaa ttggaaaaat gctaaaagct ccaattgaag aaaatggggt
    80461 tagaacggta cccgacaaag gcacgcctca gggcggtgta cttagtccct tactggcaaa
    80521 tattgtgctg aatgagcttg actggtggat agccagtcaa tgggaggaaa tgcctgcaaa
    80581 gcatcctctg caaagcgata tttatatgaa taaaaatggt accccgaata aggggaatct
    80641 gtacaagaag ttgcgacagt cccgattgaa agagtgccac atagtgagat atgcggatga
    80701 ttttaagata ttttgcaggt cgtattctga tgcttccaag ctaaagcatg cggtcgagca
    80761 atggctaatg gacagactaa agctggaaac atctccagat aagtcacgaa ttacgaatct
    80821 taccaaaggc tatagcgact tcttaggcat aaaatttaaa ctttacaaga agggaaagaa
    80881 atggtctatc aagtctcata tgactgacaa agccatcaat tctcaacgag tgaagctgaa
    80941 aaatgccatg gcgcaggcct gtaaatctca cgagagtgaa caatcacagc acgatgacct
    81001 catcagatac aaccaagcag tcattggtat gcatcagtac tataacatgg ctactatgat
    81061 aaatgcagat gttcacagac tgttcccgtc gattgacata accatgaaga cgagattgaa
    81121 tagtcgggct gacctctcca aggaaaaacc gccgacattg aaaggtgcga tggacgaata
    81181 tttctatcag aaatatgggg agtccaaaca ggttagatat atcaatggta tgattgtcgt
    81241 tcctgtagca tactgtagga cgcaaaatcc aatgttctac cgagtggaca ccaatcgtta
    81301 caccccacag ggacgtgaac gtattcaccg catgcttgct aaatctgaat atggagaaac
    81361 gctgttgaag ttgagtagag ataacgacac gaatcatagt atcgaattct gtgataatcg
    81421 cctatcaaga tttgtggcat caaagggtaa gtgtgaactc tcaaaggtgt ctcttgcgtt
    81481 tgaagatgtg gaatgcatat atcttaatcc accaagccaa ggtggtacgg atgaatatgc
    81541 aaacctcaga atcgtacaca aagatataaa gagccttatc tattctaatg acgtgaaaat
    81601 catcaagtcc ctcatcgatt tattcgattg tagggcacct gccaagattg caaagctcaa
    81661 caaatggaga gctaaagcag gattggaagc aattaacctt ataacaatta accagacttt
    81721 gaagtaactg tattagcaat aaagacttat cccatggaac gccgtgtgca atgaaagttg
    81781 cttgcacggt gtggctcggg gcgaaaggcg tgaaagcgtc tgacctatcg agatttctgc
    81841 tcaaagaaga acagacagca gcttattccg tagaaatatg gaagagattc agaaaatggg
    81901 gaggcgtacc gactggaatc acacagaata tcaaagatct tcttgccagc agggaaattg
    81961 aaaatatctt tgagaacagt gattttatcc tgatgctgaa ccaggcggca ggtgacagac
    82021 agatccttgc aaaacagttg aatatttccc catatcagtt gtcttatgtg acgaattccg
    82081 gggaaggaga aggacttctt ttctatggaa caacaattat tccatttaag gacaagttcg
    82141 ataagaactt gaagctctac agcttgatga ctacaaaacc ggaagaagtt gaaaaacgag
    82201 agaaagaaat ggaggcggaa aagcatgaag gaaatcgata agatccgaat caggcagtgg
    82261 aaccaggata atccttacat tcagatgaaa aatctggaaa atgcacagcc tggataccgt
    82321 gttcatacag tcaatgatga tcatcatctg tatgaacttc cgctggaaac acagaacatt
    82381 atccttgact gggtattctg gaatttttat ccggcacaga aaatctatcc gcatcttacc
    82441 agtgatgatc tgaaagaagt tctgtataaa cgtacccaga tccatctgca caacaatcag
    82501 ttcaaggagg ctatgctgat taatggtttc tggccgagag atccgagtga attgaactgg
    82561 gtatttcata tccaggcgag ctctccagca atcaggacac aggcagatgg ttatcctggt
    82621 atcccgatta taggacgcca ggaactgaat gagtacagaa agaaaagttg tgccaggagg
    82681 tgatgaccta tagctggaaa agaatttaaa ggcaaagata aaaaggtcgc aaagatgacc
    82741 agggatggtt tgacagaaga aaatcttcgt gatggtagtg taaaagatat cagtcacagg
    82801 agtcgaggac gaccggaaaa taaggaagaa tttgttcctg aacgggaacg gaaaaaggct
    82861 gagaatgaag attcaaaatc aggaaaagga aaacgactgc agatggagaa aatccgtaaa
    82921 tcttctgcca ggcaggaagc tgttgaggat acagttgaag ttacaccgga agaaaaagta
    82981 tccggatatc gaaagaaact gcatcgttat gaaaaaatcc cggatgatga taataatctg
    83041 aacagccaaa agaaatccat tcggaagaaa cagttgcaaa aacagatgac caaagaacaa
    83101 gcaaaagccg gaagattatc ttttgatgat gaaggaaatc agatggtgaa aggtgctggc
    83161 atgaaaccgg gagggacagc cgggaaatac attgctacac aagctgttat atctggcata
    83221 aaagcagtct ctcccgaaga ggaagaaaca gatgaaaatg caggtgtgga aagtgccaga
    83281 cttgtagagc gtgaaacaga agatgcgtta cgtggtctgc gtcatgctca gatccgaagc
    83341 aaacgaacgg atgtgaaaac ccatcgcaga ggttatcgtg aggctaccgt agaaaagaaa
    83401 ctgaaatttg gttctgcaga aagtatggaa ggagtcaaga atgcagaaac ggtaaagaaa
    83461 gccgaacaaa agagacattt ctataaccgc ttcttccaga aaaaacgata taaggatgct
    83521 taccgagcag ccagagccgg aaaatccgct gacagtctgg gtggagcaac aaccattgcc
    83581 ggtgttgaga acatgacggt aaaagcaaag atcgccttga aagagatcat aaagcgtaat
    83641 cgtgccatgt tcgcaggcat cggtattttt gcgcttcttt ttctagtcat ttcagtatct
    83701 ctggggagct gcagtgcttc tatcgaggga gctggatctg tgatcggtat tacaacgtat
    83761 ccaagttcag acgaggatat ctatgctgcc gaaaacagat atgctgcttt ggaaagtgcc
    83821 ttgaaccagc agattaatga gatggaacga agacatccga attatgacga gtatcagtac
    83881 aacattgctg agattggtca taatccatac catcttatct cgtatcttac tgcaaaatat
    83941 ggggactgga cgtactcaga tgttgaaaat gaactgcaag ctctttttga agcacaatat
    84001 catctgaata cggaaggtcg aacagaaacg gtgacagaaa ccagaaatgt tcgagtcgga
    84061 gaatcattgg gacaggtagt gaccagtgga tattgtaact gtcgaatctg ctgtggtgta
    84121 tggtcaggcg gaccaactgc cagtggtgca tatccaactg caaaccatac cattgccgta
    84181 gatgcttcca atccgtttgt gccgattggc actaaggtag taatgaatgg tgtggaatac
    84241 acagttgagg ataccggagc ctttgcaaga tatggtgtgc agtttgacgt ttactatgat
    84301 aaccatgctg cagcctctgc tcatggacac cagacctggg aagcctatat cgcagatgac
    84361 aatggcagtc aggaagtaac ggttaccagt acaagcacta agaagattct atatgtgaca
    84421 ctgacaaatg gaagctttga tgctgtggca agagccaatc tgaatgcaga gcagctgatt
    84481 atttacaatg cattaaatac gacctatgga aacagaaatt atctgtggga tgtaaacaat
    84541 gtgaccagtg gatcaggcgg taatggaatg agttatgaga ttccaccgga agcactgcag
    84601 gatgaagaat ttgcccggat gatccgagaa gcagaaaaat atctgggagt accttatgta
    84661 tggggtggct actctccatc tggatttgac tgctcaggtt tcgtatccta tgtccttaac
    84721 cattgtggta atggatggaa ctatggacga ttgaccgcag aaggattaag aggcgtatgt
    84781 acttatgtat caccgggaga agcaaaacca ggagatctga ttttcttcca gggaacgtat
    84841 aacacatccg gtgcaagcca tgtgggtatc tatgtcggta acaatatgat gatccattgc
    84901 ggggatccga tccattactc aaatatcagc acatcctact ggcagcaaca tttcatgtgc
    84961 tttggaagac tgccataaag gggtgaacga agggaggtga aagtttgaat aaaaagatta
    85021 aaaaatatct ggatgagatt gccaagacag agaaaaagat cgcggatctg cagcaatatc
    85081 ttaggggtgt ccaggctgca ttaaagcagg aagaggacaa tgagatgatc aggtgcatcc
    85141 gtggtatgaa gatggataat gatcagttat atgatctttt ggatggtatc cagagtggaa
    85201 aagttaaatt tcaggtaagc agggagtctg acgatgaagg ttcaggctcc tttgtattca
    85261 cagaagaaaa taaggaggaa tatcagaatg gtgaaatgga agaaaatgaa taagaaaatg
    85321 gcaggactgc tgttgggagt catgatgctt tttacagcat caaccacagc atttgcctat
    85381 gtggatgaat cagcagaggc atccaaagta gagacaactc agacggaaca gtcaacagac
    85441 aaagaagaga aaaaggacga ggcgacaaac acaaacgagg tgctgccaga agatggaaca
    85501 gaccagggaa ctgcatttac gacacctggc aatggtgaag tcaaggatga cattaccgat
    85561 gattccacaa aggaatttct tacggttaca acgaagaata acaacacttt ctatatcgtg
    85621 atcgaccgca gtgccacatc ccagaatgtc tatatgttat ctcagattga tgagaatgat
    85681 ctgtccgagt ttctggataa agacagtaca gctgctgttg taacaccaca gccggataca
    85741 tcgaaggttg tgctggatga gacaaataat gaggatgtag acaaggaagc tactgttgat
    85801 cctgagaaaa catcatctgc aaaaaccaat atgggtgcaa tggcaacaat cctgattttg
    85861 gctctcggcg gcgtggcagc ttactactac ttcaagatct ataaacctaa aaaagaggaa
    85921 gatgaggatg atcagccgga aggtttggaa acaggtggac tggaagaagt tccggatgag
    85981 gaagagtctg aagacgaaga ttttgaagaa aatgaaaaat aaataaactt ttttagcgga
    86041 gggggctgta aaacatgctc tctccgtttc gttatatgaa ggaggtaata catcttgtat
    86101 ttagtaattg cagaaaaacc aagtgtatca agagcaatcg cagaagtgat tggagcacag
    86161 gaacgagaag acggatattt acaaggaacc gactgtatgg tcagctggtg cttcggacat
    86221 ctggccgaat atgtttcacc ggatgcttac gatgagaaat ttaaccagtg gagatatgaa
    86281 gatctcccga tcatcccgaa agactggaaa gttacagtct cagaagataa gaaagatcag
    86341 ttctatatct taaaaagact gctcaacagt ccggaaattg aatacgtcgt aaatgcctgt
    86401 gatgccggac gtgaaggaga attaatcttc aaacatgtct atgacttatc cggaagtaaa
    86461 aagccggtga aacgattatg gatcagttct ctggaagatt cagcaatcct tgatggaatg
    86521 cagcatctga gatccgcaga ggaataccga catctggccg aagctgctgt atgccgttct
    86581 caggctgact ggctggtagg aatgaatgca accagagctt acaccacaaa gtacttcaaa
    86641 aagctgaccg ttggaagggt tcagacaccg acacttgcca tgttggtgga acgtgccgga
    86701 cagatcagca atttccagaa agaaaagtat ttcaatgtgg aactcgattg tgatggaatt
    86761 ccggctgtaa agccaaaaat ctttgatccg gatgaggcgg aacagttaag aagcagatgc
    86821 caaggaagtg aagctattgt cacagcagta aaagaaacgg aaaagaaagt aaaagcacca
    86881 aagctttatg atctgaccac actgcagaga gaagcaaacc gtatctacgg aatgacagcc
    86941 aaacagacac tggataccgc tcagaacctg tatgaaaaga aactgatcac ttatccaaga
    87001 acggacagcc agtatctgac cgaagatatg gagcagaccg caagaaatgt ggttcgtcag
    87061 atttatgaga aatatcaact gacaggtcct tttgatcagc cggaacagcc ggatgtgaag
    87121 aaagtcatga ataacagcaa agtgacagat caccatgcaa tcatcccaac gatggagctt
    87181 tcatcctgcc atctggatga attgaaatct tgggaagaaa agattctttt cctgattgca
    87241 gttcacacgg tcatggcaat gagtaaggag cacgtttacc aggaaacaga gattgaagtg
    87301 gaatgccagg gagaaatctt caaagcaaaa ggaaaaactg tgttgcagga tggatggaaa
    87361 ctctttgaaa actgcttcaa gaataaggac cgcatggcaa tcgtagatcc ggatcaggaa
    87421 atgaaagaga agatcccgaa agtaacccag ggacagactt tctatgctgt agctgcagaa
    87481 aagacagaac atttcacatc accgccaaaa ccatacagtg aagatacgct ccttgcggca
    87541 atggaaactg ctggaaataa ggaattcgat gaagatacag aaaagaaagg attaggaact
    87601 ccggcaacaa gagccggtat catcgaaaaa ctgatctatt cccagtatgc cacccgaaaa
    87661 ggaaaacaga ttcttccaac agaggatgga aaagtccttg tggagatcct gccggacttc
    87721 ctgaaatctg caagtatgac tgcagaatgg gaaaaccagc tgctcttgat ggagcatgga
    87781 gagattgcac cggaacagtt tatgaccggg atcaaaaaca tgctgaccat gatgctgaat
    87841 ggatgcgatg cgatttccga agaagaaaca agaagatttc agaccagaga aagcattgga
    87901 acatgtccgg tatgtggaag cctggtatat gaaagcaaac ccaacttcta ttgcagcaac
    87961 catgattgtc actttgcgct ctggaaagat aaccgctatc tgcagagcat ggaaaaaacc
    88021 atggataaaa agatggctgc agaacttctg aaaaacggaa gtgtgcatgt gaaagacctg
    88081 tattccagaa agaaaaatat gtactttgag gcagatctcc atatggatac agatgaaacc
    88141 ggaaaggtga atttttcttt atcctttccc aaaaagaaat caaaaaacaa aagcaaaaag
    88201 aaataaaaaa acagattaga ggaggaaacg aagaatgaat tttaacgaat ttgtaagtga
    88261 agtaaaggat aatatcaaac tctttttacc agaggagtat gagaatgtag aagtatcaac
    88321 gatggagtgt cagcaactga accgtgccta tacgggattg atggtgagaa aagaaggtga
    88381 gatgcttacc ccgacgatca atcttaatca gttgtatgaa gcatataaag cacagcctgg
    88441 cgtaacaatg gaaactgtat gcagaaagat tgcagatata gttattgagg caccgataca
    88501 ggttgatctg aaagctattt ttaattatga agatgtgaag gacaagctgt ttatccgtgt
    88561 atcatcagcc gaagcaaata aggaagtcct cgaaaatgct ccacaccagc tgaaagaaga
    88621 cctcgcaatt acctatcatg tggcagtaga caaggatgag aatggattaa gttccatgtt
    88681 tatcaagaat gatctgcttg aacagtatgg aatctcagca gaacagcttc atgaagatgc
    88741 tatgaaaagt tcaccacgag ttatggtccc ggaggtatca agtataggtg cattgataga
    88801 tgaaatgtat cagaaaaata ttctcatgct gacaccggat gaacgtgaaa tgctgcagga
    88861 aacattgcag gaatcaagtg agatgccgac attctttgtt gttacaaata cagaaagagt
    88921 tgatggtgcc ggtgtgatct tttatccgga attcatggat aacatggggg aacttctggg
    88981 aaatgatttc tttattttgc catcatccat tcatgaaatg ctgattttac cggatgacgg
    89041 gcaagtggat gctgaaatgt taagagatat ggtaaaagaa gtcaatgcga ctcaggtagc
    89101 accagcagaa cgccttacca atgatgtata tcactttgac acaaaggatc acgtctttga
    89161 aaaagccgac agatttacag aacgtcagaa agaaaaagaa gcgcaggctg caaaaacaga
    89221 gaaagcagga aaagaacagc cggatcagaa accgaaaaca aagaagcacg atatggaact
    89281 ttaataaaaa ataatcatct cgtcaactaa taaaaagccc tgcggcataa acacaatgtc
    89341 gtggggcgtt tttggaaagg agtattatga cagaacaaaa caaaactact actattccac
    89401 tgccggttcc gggaaaagat atggacagca ttatgcagtc actggaatcc ggtgtggaag
    89461 aactatttac aagtaaccgc tatcaggaat ttcttaaaac catggcaaag tttcacaatt
    89521 attcttttaa taatacaatg ctgatcgcta tgcagcgacc ggatgccaca cttgttacca
    89581 gctacaaaaa ctggcagtcc atgggtagac aggtcatgaa aggtgaaaaa ggaattacaa
    89641 tcattgcccc ggcaccatat aagaaaatga aggaaaaaga ggttctggat gaaaatcagc
    89701 gaccgatcat gggaagcgat ggaaaaccta agactgaaca ggtggaagtt acagttccgc
    89761 attttaaagc agttacggta tttgatattg ctcagacatc cggagaaccg atccagacac
    89821 tggcaccaga attactgact gcagctgtac aggattttga ttctttcatg caggctattc
    89881 agaaaatatc cccagtaccg atacgattcg atgagatcga tgacaatgct aatggatatt
    89941 atcataatgc agataaggaa attgtgatca aaaaaggact cagtgaaagc cagaccttaa
    90001 agactgctat tcatgaaaca gtccatgcaa aattgcatga cagggagatc atggaaagcc
    90061 ttggtgtaga aaaagaccga ttgacaaaag aggttgaggc tgaatccgtt gcttactgtg
    90121 tgtgttcttc ctttggtttg gatacatcgg attatagttt cccttacatt gcaggttgga
    90181 gcagcagccg ggaaatgaaa gaaatgaaag catctatgga tgtgatccgc aagacagccg
    90241 gtgaaatgat cgatcagctt acagaagagc tggaaatcat tcttgaagaa aaacagaaaa
    90301 cagaattaca tgataaatac ggcattctgg tagatgcact ggaagcagcc ggataccgct
    90361 atgattatcg ggaaagcgaa ccgggacata ttgtactggc gccggatggg acacatgaaa
    90421 ttgccggata cttgcagttt gaatcatggg gagatatcaa agactggctg gaagatacga
    90481 ttgcagaagg aacggatatt tcggaaagag ttgatcgggc tttgtatcca tttaagtttg
    90541 attataccct agaggaagaa atgttcagag gtaatggtga ccgctatgcg atttaccacg
    90601 tggatgaaga cacacctgga aaacaacatt tatttatgaa tatggcaatg gtcaaagaag
    90661 atggaattac aatcgatgca gcaaattata aatgtgtcta ttctggcaga ttacatgaaa
    90721 atgaaaagct ggatgatttg tatgccgtat tcaacgataa tccaccggca gattataaag
    90781 cacattctat gtcggttagt gatgttatca ttacaaaccg tggtggggat atgcaggcat
    90841 attacgtgga tcgatttgga tttgcagaac ttccagactt tgcagtacaa agagaaaaaa
    90901 tactcgatat tgtcccggaa atagaaaatg tggattatga aaatgatctt acatgtatca
    90961 gcttttatgc ggctgaatgt gctgaatttc ctgtgatggg tgaagtacat tatgacctga
    91021 cattaccgga agccttggaa gcttatgaga aaatcccatc agaacgtatg catggactga
    91081 aatgtgttgg ctttgatctg aaagacggaa gtgattatga aggaatgcag agtctgatga
    91141 tcgaaggaaa aatacagaaa gaatttttga attcgattcc tggatttaga gaaaattctt
    91201 atgtgcaaaa tgcaatcagt cgtgtggaaa agtacttgga agaaagacat ccaaatgtgg
    91261 aaaatcctct ggaatccaat aagaaagtgg ataacgaaaa aaatataagc aaagaaaaaa
    91321 acgagaagga gctgaatata cagatgaaac caataccgaa aaagaaaagg ggggaaatga
    91381 gcctatgaga aatgtaaacc tggaagaaaa cgaactgact attactgcta tcttccagca
    91441 gcacacaaag gaagaaacaa tccaaacact gaaagaagct ttggaagtta tggaacagga
    91501 agaaagtgat cctgagaatg atgaaatgat tgagatcatc aattctacag ttggaaaatt
    91561 acagcagatc gaagacaaat actactattc tctggatctg aattattatc tgaataactt
    91621 ggagaacgat gcctatgaag cttaatcaat ttgcagtcta ccgagtagat cagcagacag
    91681 caggaaaagc actgtggcat ctgccatatc aagaggcaag acagcagaat gtgtcgatta
    91741 ctgtcgaaaa ttaccgatta gtctcgattc atgaaatgca ggaaaatgaa aaagtcgctg
    91801 acatctggaa acgaatgaaa aagcaatgcg aagtcagtga cgtgctcgta ttgaacaaga
    91861 acggagaaat cagttgctac tatgtagatg aaaactatcc acagtatctg gccggattca
    91921 ttcgtatcaa tacatccggt gcactgatca ctatggaaac tgagaattat cagatcgatg
    91981 ggaaaaaagg aaactggatt gccacagaca ccatcattat tgatggaaaa cagttttatt
    92041 tgatggaaca tcaggtatac cgagatcagg cccagggtgt tatcctggat gcctatggaa
    92101 aaatggttgt cgaagaatgt aagaaattcg atgaaaagac aaaacaaaag attcatgatt
    92161 acatccaaca gcaagtaccg ctaaatccgg tcgaacagct aaaacaagat ggtaaaatcc
    92221 gtctggaaca ttaccagaaa ttctaccaga acggcactta tgaacgaagc agagaatctg
    92281 gtaccgaagc caattatgat atggtggacg gtctggtgaa taatcagaag aagaatcagg
    92341 aaaagacctc tgatgctagc agcaacaatc agacctcccg aaatcaacag gatggaaaat
    92401 ctaagaaacg aagatccgtg atcaaacgtc tgcatcagaa acagattgcc attgctcgcc
    92461 ggtccggaaa accgataccc aaatacctgg atcaggaaat ggaaagaaag cgggggtaga
    92521 atatgcgaag gttaaagtgt gaaaaagaaa cgattattct gaccaatgaa gatgacggat
    92581 tctatgatgt gtataccttc aatcagagct tgcagaaacg gttacgggca ttcgctgaga
    92641 agtatccgga tgattgctgg ttgaaaggat cttcggagga tggcagtgaa acgtatataa
    92701 tcaaaaaggg ccggttgtca ttgaatttaa gaccacccta ttctaaggac agaattcata
    92761 aagcaacaga acgaattatt gaagaacaga aggaacaatc aaaggattca tagaatgcga
    92821 tttaagagaa aaaagcctca tgaccatgag gaaaaatgaa agcaaaatat gttagctgat
    92881 aaagtgtata ggctcaaaag ggaaagttcc cttttgggcc ttattttgtt taaaatcatt
    92941 tagtagtaca aaacctgatt ttatctttta tatatttgat aacaagtagt gaatagttga
    93001 tttaagtagt tttcagtggt acaattattt gaggaaaatt catgtaatag tattaaatgc
    93061 agggagaaaa aaatggcaag accaaaaaag aatggaacat accttaatgt atgtattgaa
    93121 actcctattt atgagcgatt agaaaatttt tgtaaagatg caggacatac aaaaacggtt
    93181 gctgttgaaa gagcattaat ttcttatttc gatgaatatg aagaaatgaa aaagaaatta
    93241 aaagaattag aatctaatca agacaaatga gaaattcatg caggggagaa tcaagcaaat
    93301 gatcaacggc aaagatcaag aaattataac tataaataaa acaggaaatt caatattaaa
    93361 taacgcaaaa tattctgcag ataacacgga tgaatggtat actacatttg ttgcgcgttc
    93421 ctttgatttt ggacgcaaaa aaagattgca gccgccatgc gctgcaatct cccgatttct
    93481 catattgtga ggttaatcct ctgctttttc gacttccgtt atctcccttg ctgttgcggt
    93541 tacaatccgt atgcctttat cgctcatacc gtccagcagc gcgtcaagct gccgccgccc
    93601 ggtggatttc tccgcattgc tgttcgggaa gaaaaattga tctaccgaaa tatgataccg
    93661 ggttacaagg tcatagaata cctgtaaact cggctgttgt cccttgttct cgatattcgc
    93721 aaggtagcgc ggggaaatat ataactcgtc gcttaccttt ttgcggctct cgccgtattc
    93781 atttctcgcg gcttttatag ctgccccgaa agccttaaag tcgtacaatg gtacgggtct
    93841 ttttgccatt ttcattcacc ctgttacatt ttacagttca cctttctttt tggatatgtc
    93901 cacacaattc atatcattag gttaaatact tcctgttgtg tattgacagt agactgattt
    93961 tctgataaaa taaaatttat gtaaaaggag gcggcgttta tgttgcatag catgcgtatt
    94021 agataagcat tgaaaaaaag gattttccca ttttcaacat gggctttttt gtcatgctta
    94081 ttttgcggat gctatacaaa aaactaacga cgtatagata tagtatagac atagtgcaag
    94141 ctatgcctta gttttgttgt actgctctgt gcattataaa tgcaggtcaa tgctcatgtt
    94201 gaggattgac ctgcattttt ttgtgtaaaa aggacgagtg aaatataatg cttaaaaaat
    94261 attggataaa atgtccgatt tgtaacggaa agacgagagt tcaagtattt cataatactg
    94321 tattaaaaga ttttcctctt ttctgcccta aatgcaaatt gacgcatatc attgatgtag
    94381 aaaaattaga gattgtaatc aaaaatacag aaaaacaaac ttttattatt tagaagaaag
    94441 gatataaaaa tgaaacgttt acctaaatat acgcctgcgg aagtacggaa tgatccatac
    94501 ggatttactt acaaagaaat gtcggaagtt attggcgaga atgaagcaaa agccttatat
    94561 gaagaattat ataagcaatt accacgcaaa aaaaatctat caatgttggt aaaaaatatt
    94621 tgcaaaagca gtgatactga aaagtatgtt tacgaactga aagacaacaa atacattgaa
    94681 acggttttta tcaagcggcg agatggtgga actgtttgcg tgagcacaca agtcggttgt
    94741 cctgttggtt gtattttttg tgagtccggg cgaaatggct ttgttcgtaa tctaacatcg
    94801 tcagaaatcg tacaacagat tatattgttg cgtcgaaaag taaaccgtat cgtttttatg
    94861 ggtatgggag agcctttatt caattatgac aacttgataa aagcaatcca tattctccga
    94921 gatagatatg ggctcaactt tccaaccgac ggcattacca tatcaacagt tggtccggtc
    94981 gatcaattaa aaaaattgcg cgaggaacat cttaaaattc agttgacaat atctttacac
    95041 gcagcaacac aatctgcaag aaatcgtatt attcctcaca tgcgcatata tgctattgaa
    95101 gatgttgtta agcaagcctt atcctattct gaaaggcata atcgcaaaat tgtctttgcg
    95161 tatttgcttt taccgggtat aaatgaccgg ccctcagatg taagacaact tgcaaaatgg
    95221 tttcggggca aaaaagttat gattaacgtg ttacaataca acccaacaag caattcaaga
    95281 attaaagcac cacagaaacg ggaaatagtt gcattcaaac atcaattaga gcaagcagga
    95341 cttgaagtta ctatgagagt ttctcatggc agagagatta acgcggcttg tggacagtta
    95401 gctaacacat ataataaatt caaaaaaaaa tgattaaaag tgccagacgc atagacgcag
    95461 agccgataac gcattaggtc aaaaaaccta tgtgttatcg gcttttttat ttaatattgc
    95521 gcaaaagccg ctgttcccta ttatagaatg gattgcgggt agtgtattaa agtcgccctt
    95581 ttttaaggat acggcggtat cggggaggta tcgccgtgtc catttttatt tactgtaacc
    95641 cgcctaatgc tttgcggtca aaaaaagcta tgctccgcaa gcgggatatt ccggctatga
    95701 atgtgaactg tcaatacatt tagctactgc ttacggttat gggaaatact aattctgttg
    95761 tatggagatt gtacttctac cttcatggtg ggaagtaccg ttgcactggc agggattttt
    95821 ttaactggct tcccgccatt ccctgatgtg ctatgtataa ataaactttg ctttatataa
    95881 gcagatgggc aaccgcccga aaaaaggaac ataaaaaccc tccaaattta aaaacaaatt
    95941 cagagggtaa tttagggtat aacaaaataa cccacccgaa tatcgttttt tttatttggt
    96001 gagtttgttc tttcaaatac gaaacaaaaa gagccgatga ttcgtgaatt gttccacaat
    96061 ttcatcggct ctgcgtctta agcgtctggc tctttgatga cagttatctt caagttgtca
    96121 actttaatca atctttcttg tctgcatttt ggacaataaa ggggataatt cttcaaaaca
    96181 gtgtccttcc taattttatt acgggttttg ctcccacaaa caggacataa tatccattcg
    96241 catttcatca taattagctt ctaatccttt caaatctcat tttatacgac ttatgcaagc
    96301 tgttaggcta acttgtggaa catatgccga accttatcta tacggctatt cgggcggcgg
    96361 ggttggcaaa taagtttacc agtagctggc tggtatcctt ttaactctgt caagcagact
    96421 ccctgcccat ttgtgaaata agttaaatcg ttcctgtatt cttgaataca tctagcaggg
    96481 atttctcctt tcagaatgac ctcgtcattc tttatctgag tacttacaat atctgcacaa
    96541 taccttggag catcatgata cgcccgtgag agatattcct gcggtgcata aatttcaaag
    96601 tggagatatg gctctaatag ttctgtccct gcttttttta aagcctgctc caatacgata
    96661 ggggaaagca gccgaaagtc tgcgggggta cttacaggac tataatacaa tccatattca
    96721 aaacagattt tacagtctgt cactttccat ccatacagcc cctgctcgca gccataaaga
    96781 accccctcca taaccgcatt ttggaacgat tggtttaaat atccaagtga aactctgctt
    96841 tcatactgca ctccacttcc aatagggagc ggctctatgg acaacccgac agaagcccag
    96901 aaaggatttg gcgggacttc tatgtggatg gtatattctg cttttctaag cggtctttcc
    96961 atatatataa cagtaggctc ttttatttct gcctccacat gatatttttc ctcaaggatg
    97021 gcacaaatga cttccatctg cactttcccc aaaaaagaaa gtataatctc atgtgttgta
    97081 gtatccacat aatattttaa aagagggtcg ccatctgaaa tttctgtaag tgccccaagc
    97141 aatatttccc gctgttcaga tttctttgct gcaatcgttg tttggagcat agggagagga
    97201 ttttcaataa atgttctctg cggcaacagc atttcgttcc ccaaaatact gtttagctgc
    97261 aaaacatcat ttggtaaaat tacaatatca ccagagcagg ctgtatcgga tgaacataat
    97321 tcaccgtttg tcggaacaca catctctgtg atttttattt tctctttttc agatatttta
    97381 ataacatccc tcaaatgcaa tgttccgcta tatatacgca cataaacaaa acgccgcctt
    97441 ttctctgaat attcaatctt aaaaacctgc ccgcatagtt cagattgacc ttcaggcgtt
    97501 gatgaataaa acttactggc aatcacttct ataagctgcc gaatccccag attgttttta
    97561 gcgcttccgt gataaacggg aaataacgtt ccgttttgga atctcctgtt ttcttcctgt
    97621 tccagttctg acattttaaa cggtttccct gacatatatt tctctaatag ttcatcgttt
    97681 cccataatta ccgcatccca ctgttccata tcgtcattgt ccgttacatt tatatgagga
    97741 tgctgcccaa ccttttgctt cactataatt tccgaagaaa gctttgcttt catttcttga
    97801 tataccattg gcaaatcaat cccctcttgg tcaattttat tgatgaaaaa aattgtcgga
    97861 atcttcattg tctgtagtgc atgaaacagt atacgggtct gtgcctgtat gccatccttt
    97921 gcagaaacta ataatactgc tccgtctaat acggataaag aacggtatac ttccgccaaa
    97981 aaatccatat ggcctggcgt atctataatg ttgactttta catcctccca ctgaaaagat
    98041 gtcactgctg tctggatagt gattcccctt tgacgctcca aattcattgt atctgtcctt
    98101 gttgtgcctt tatctacgct ccctggttct gcaattgcac cactggtata caataaactc
    98161 tccgttaatg ttgtctttcc tgcgtcaacg tgagccagaa tgcctaagtt aattattttc
    98221 atgtgatttt cctcctatca acacccaaaa aagggcataa aaatacccag tgataaatac
    98281 tcctatcact gggtaaataa ctccaatagc cccaaaacac ttatatgttt tcgggcatat
    98341 aaaattacat gataaaagta ttcttaaact gggtacaaaa aactaagccc catattaaaa
    98401 gtgaaacggg actgctactt tttgttccca ctatcaaatt gacagtttat ttaagaatac
    98461 cttgccgcat atttattaac tccttgtata atactgaatc taattatatt ccttaaccct
    98521 ttatttgtca agctgacaaa ctaaagcaga aaaagcggca ggatttcccc ctgccactaa
    98581 tcatctgttt atgcaaaaat aatttccttt tccacaatct ccctcgcaca agcccttatg
    98641 ttattcgttc ttccagtcca ttctaaggcg ttttcttcct ttaggcattc cgttatgccc
    98701 tgtgcttgct tcatgccctc tatgagccgt tcaaagtgtt cctgtgcctg tctgtcaatg
    98761 tcggcaaggt aagcattgag cctgccgctt gtgagaagat tggtgtatgt aattttgcgg
    98821 tactcccgca gatagtccaa gtgccgccgt ccgaataagt ctatcgactg ttccttttcg
    98881 ggtggtatgg taaggcaggg taaaatgtat tcgccttgcc gttcgtatct gccgcccatt
    98941 tcctcaaaga ttgattgtac catttgtttt tcctccaaat aagatattca ctccatactc
    99001 atgtctgcta tcattaacac aatttacgtt ttctccttat ctggtttcat acattattta
    99061 aaattaaata aaaaagttaa ttgggtaaaa tcatgttttg ctacatgtga taaagatgaa
    99121 ttgtttttag gaaaaaatgt attaaatgcg agaattacac aagaacagtt tgttgaagaa
    99181 atgaaaaaaa ttaaatagta ttaagataat aaaacgccca ctttgtaggc gttttatttg
    99241 aaatacagat ttaattcaac tatataattc taaggaactt aataaaatga agaaaaataa
    99301 tataacactt gtatttgttg ctatcgtttt ttcgattatt gttggaatga taattggaaa
    99361 aagcttatta aagtataaag aaggtgagcc agatgtagtt ggcagttttt ctatgaatag
    99421 agatgaaaat tttacagtag ttgctaacag aaaaaatatt tctgataaag aagcatttgc
    99481 aagactgctt ttaaaaatgt acaaagagaa ttcatttcat tcaataaaat tttctacaga
    99541 tcatggatat gcaaccagcc ttgatatgac cgtatattct tggaaagaag atatcgaaaa
    99601 tggcgaatcc attatgcaaa tagaatttag accgattgaa tatggaaaag attatgatct
    99661 tgttcataat ccggataaat atgtgcttct tatcgatgga acagaaataa agtgaaatat
    99721 atagatatgt agataaagcg cagaaaaaga ggattgctca atacaggtta ttttcaatta
    99781 ttacccctaa aatgataaaa gagaggcagc ggataatccg ttgcctcatt acagtatacg
    99841 acacttaatc tagttccgcc cctaactcat acctccaata ctccgccgcc tcatactccc
    99901 tgggttctga gagtaccggt acggtaaaga gttcaaccgg aacaccgagt gttgatgcga
    99961 agagcttcat aagatcctct ttcggtgttc ggacatcact ctcatactga gcaatccgga
   100021 catcagcaca gctgtcggga aatccaacag ccatgccaag ttctttttgg gtgagatgat
   100081 ttttttgtct taagtgtttt aattttcttc caaatgtaat catagtatta ttctcctgtg
   100141 cttccgaatg ccccagttcc tcgttcttca ccaaggtcca ggacaaaatc tgcgatcacg
   100201 accggtgtaa tcaccagctg accgacgcgt gtgtctttat gaatggtctg agaagatgtg
   100261 ctcacgttgc ttataatggc atggatttca ccacgataac cggagtcaat cggtggaagt
   100321 tcacatacca gtccttttgc tgccatgctg cttcgtggaa agacatatcc ggcaaatcca
   100381 tctgggatga tgagaccgaa tccaagcgga attcttgcaa cctcgcctgg ttttaatacg
   100441 caatcataag gcatgaatac atcagcaccg gcatcatttt catgtggccg gaatggatga
   100501 tgatctgctt tcagaccaaa gtcaatcagt ttaatcttta tggctgctca tctccttccg
   100561 gatcagcaat ggataatctg tttttaagat atctgcaggc atccaaagtt ttgaaatggg
   100621 attctgacag gacatctgtt tttccatgca gcttcctctc tgacagaatg gaccggtcag
   100681 atctggtgca aaaagaatcg ggcttaattt gtacaatctt tgccagatat agagcatcac
   100741 aatcctggtt tcatccgtat tccttctgca ggttctctga ccaatcatat gcttccactg
   100801 gtaaggtgtc gcgctgatga tcagtacgtt tcgaagtccc tgaggtgtgg catatccggc
   100861 tgaatcatga tcaatgccta aggcacaaag ctctgcataa tgatccagat ctgactgaca
   100921 gcttttcttg taaatatcct ggatttcttt atctgctttc atgattccat atggaatagc
   100981 aaatgcagca tgaccggaat aattgctgta ctgcagagat gcactcatgt actttacttc
   101041 attctgatgt cttgtgatct gtgccaggaa gcgtctgctt gcaccaacaa cagctacggt
   101101 aatgaccatg aatttctgca cggttggatg cggaagccct gcaatgtttt ctacagtctt
   101161 ctgactgtag gattgacggt aaagatccat cagatctgcc atgttctgga tcgtatgacc
   101221 gtgttgtgtg agtctggcag caaagaccat attctgttct gcttcccgga ttccatagca
   101281 gtttaagata gctgtttcaa tgtgatccat aggcctgttc ctcctttacc agagctttta
   101341 aaaggatcag ataattgatg cagtctgtga ttttttcatc ccactgttcc atgtcaaaat
   101401 gtaacagagt ggaataacac atatcgtaaa gggatacgac atgtttcgac atcataccgg
   101461 ccagtgctgc ttttggatcg cagttttgta aggcggcagc aatcttgaat gcactgaggc
   101521 ggtcaatatt gtcaccggta tattctttct ttttatgtgc cagaatatcg gcacactttc
   101581 tcatctgaag ttcaaataca atattaaatt cttcttgtgt catgtgatag ttcctccttt
   101641 gttttgtgat agttatcgtt cgagatcttt gttttttgat cttactggtt ctggtatctg
   101701 catctgaaga atggcatcaa cattctgatc ggcagtatcc agatctttta atttttcttt
   101761 caagctgctt attgcttctt cttcggaagc tatctgctgt tgcagttttt ctttttgcaa
   101821 agtcaaggtt tttaggcttg tcatatttcc atcctgataa aaggatttca gccaatttct
   101881 ggcttcttca tatttctgaa tttccttcgc atgttctttt cggtactttc ctttgtactt
   101941 tgcttttgaa aactgggaat aaacttcctt gtttgcatag tactgaccgg tataacgaat
   102001 ctgatcgttg aggatcctta gatcggaacg atgctgagca aactgtgtct gcatttcttt
   102061 caattcctgc tttgatgcaa ccagtgtatt tttcaaatct gactgcgtat caaatccatg
   102121 ttcctgcacg tagataatgg tatttgccat ttgctgcagg ttagaaagtt ttacccgatg
   102181 agcataagcc gggctctgca ttgctttcac atttgtctgg agatttacaa ccaggcgcag
   102241 gtgagatctg acgtagagaa tggccaatgg atccttgcgt aagaaggtct gtttcaggtg
   102301 ttcttttcca tatcgtgttc ccagtgaacg ttcagtaatc cgcttctgtc gatcaggatg
   102361 aagatagctg tatctgccac gatgctcaat tacagagatt tgaaattgtt ccagaagttt
   102421 ggattggaat tcatcaaaac tattggatgt ggaagcacat tcatcaatcg catttcgcaa
   102481 atattctttc tgcgtaagga atacagtgga tgttggtttg agaccatctt cgataatttt
   102541 ctgattgatt tcatccagtt tttgctgacc atgtttctgt gctatatatt ctttttgagt
   102601 agtttttctt tcagctggaa caagaagatc tatctggtga aatccttctt gttgacaccg
   102661 ttccatgact gttttcttga atgcgttcat gaatttatcg gtggaacgat gcttgtaacc
   102721 ggcagcttcc tcatgtggct tatccatata cggctgcctt tccactgcag tcttcctcac
   102781 actgtttatg acgatgtggg tatggatatt tccggactca ttgtgaccgt cagtatgagt
   102841 aaccaccagt gcctgatatc caggaaacat ctgctttgca agttccaaac tgattgcttg
   102901 tgctattggt ccggtaagtc cattttctgt aacatcggct ggatcgtagc tgataatgta
   102961 gtggtgactt ttgatatctg cacgtttctt atttttgtga aaatgagcat ttgtcagttc
   103021 acattccttg tcaaaagaca tcggatcaca gttcagccca tccatataaa actcttttcg
   103081 catgatgctt cgtccggatt cgtctacaat ctttttcccg gttttttcat catgttcaaa
   103141 cagaaggtaa ttgatagcag ctgagtaatt tgcatttctg cttttaatgt gttttacgat
   103201 tgccattcat accacctgcc agtttcagta cctcttttct caataggaat aagtccgtga
   103261 tgcactgatg gatttcattt tctatagcac gtgactgact gccaccgctg ttaaaatgct
   103321 tggcaatctg attgagattc gatccaattt ttccatattc actgaccagt tttctgagat
   103381 cattcatgtc tgcaaccact tcaatctgat gattgatttg cttttcaagt agtagttttc
   103441 tcacatattc agaacgagaa agtcctgtaa cgtcagcggc ttcatttaat actgccaatt
   103501 caatatccgt taattttaat gtgatgatgt tactcctttt gagattcttt tctttcttct
   103561 ttggtgccat agtcctcctt cttttttgat aagacatctt ggatgtgcga ttacactttt
   103621 taaccggctg tcccttccgg ttatataaag tgctgcgact atctttgata gagagccaac
   103681 agatatcttt gatgtctgta cgagggtatg gggaatcgga atccccatca agagacttac
   103741 ccggaggtat gccgtagcca taaaatggcg atacggtaat acctgggtgg atcttgctct
   103801 tatttgtatc cctctatata acgaaacgct cagaggctgt tttacagtgg ggaaaaagaa
   103861 aaaatatcaa aaaattgatg attaatggtg agcttgtgat agaatggaaa aaagagaaaa
   103921 gcataaagga tgtagttgtg gagaatattt gttatgatta gaaagttgct gaacggagat
   103981 atcgatagaa ttgctgacat atggttaaag acaaatctga aagcccatta ttttatttcc
   104041 aatcaatact ggaaaagtaa ttatgaatta gtaaaagaaa tgatgtcaca atacgaagtt
   104101 tatgtgtttg aagcagataa aatgatacaa ggatttgtag gactaaatga taaatatata
   104161 gaaggtattt ttgtctccga tgaaatgcag tcatgtggca taggtaagct tttattagat
   104221 tatgttaagg ataaaaaagt tagcttacga ttaaatgtat accagaagaa tgccagagca
   104281 atttcttttt accaaagaga agggttcatt attcaatatg aaggcttgga tgaaactact
   104341 ggtgaaaaag agtacactat gctatggaaa cgaaaataga aatcggaatt tatcagaaaa
   104401 tgaagaatag ttgaaatgga ggcgctataa taacatgaag attgaaggga accagaaaga
   104461 actggatgca atggtagaat ttcataaggg aaaccgtgtc gagggactga gactgcaaga
   104521 agaatttgca gcggaatttc gtaaggagta taaagacaaa gatcactgtc cttgcctgaa
   104581 agcctgtcgt tatcacggaa actgtaagga atgtgtagca atccacagag cgcatcagga
   104641 acatgttcct aattgtatgc gaccattgat taataaaaaa ttgaaattga tgtcagaatt
   104701 aacagagcat accttggcaa atgaaataga agctccacat gagattttaa gaaaataggc
   104761 aagtcaaatt caagtttaca gaactgaatc aaaagagctc gaaggagctc tttttccttt
   104821 tttataatag tatcattatg gtataataga gacattaaaa tcggaatttg tagaatagag
   104881 gaattatgat gtttgataag cacaaaaggg aatccttgct attgcgggac ttattaaaga
   104941 aattgataat tattgtgata ggttccattg ttgcagccta tggcattaca cttgcactgt
   105001 atgcaggatt tggtggcgcc acgctcgcag tgctatggca gggtatcgct gaaacgtttc
   105061 acttgagcat cggtatggca tcttttgttg tagcagtggg gatgattttg tttgcattaa
   105121 tttacgataa aagtcaaatc catattggga cggtgctata tcaaattgta tacagcacct
   105181 gtgtagatgt atttgccacc tgccatgtct acagtacata tcgatggttc aacttcttta
   105241 tcatgttgct gggtgttatt ttgtttgctg tcgggaccgg actatatgcg tctgcctcac
   105301 ttggtcgtgg ctcttatgaa gcagttactt ttgccttggc agaaaagaac aactggcaag
   105361 ttaaaattgt tcgaatagca ttagatattc tggttgtgat aataggtgtt ttgcttggcg
   105421 ggaagtttgg catatgcaca atcattacag ttatcatttc aggcccgatt atccaatttg
   105481 ttaatgcgaa agcaaaacga attttaaaga tataatagca aagaaaccta caacttcaag
   105541 tttgatgaat taaattagat ggcaattgat ggagtaacaa gttgtatgaa aattcgagaa
   105601 gttaacaaaa ataaaaagca gtttatatca ttattgttat tagctgatga acaggagagc
   105661 atggttgatc gttatcttga aaaaggaact atgtatgtgc ttgaagataa tgatgtaaaa
   105721 gctgaatgtg ttgtcaccga tgaaggtaac ggaatacttg aaatcaagaa tatcgcagtc
   105781 gatccggaaa accagggaaa gggctatggc aaagcactaa ttgattttct tgccagtaaa
   105841 tatgcagatg aatattctgt tttgcaagtt ggaacaggtg acagtccatt gacgatacca
   105901 ttttatgaaa aatgtggatt tgttcgttct cacaagattc ccaatttttt tactgacaat
   105961 tatgaccaca caatttatga gggcggtgta cagctaatag atatggtata tttgcaaaga
   106021 catatataaa ttcaagtttg ttgaattaaa aatgaaataa agtttcagta atcatagagt
   106081 gtatggattc aattccatat gctctttttc tttacttaat ttcatgaaaa atgtaaaaat
   106141 ctaatgttac gagtttctta cgagttgcat taaaaaaact cgcaagaaaa aaagtaaaaa
   106201 aatttgcttt tgaccactgt aaaacatgct ctgagcgttt cgttatatga agggataatt
   106261 tttctttcat atttcaaaga aaagaggata aagaaatgtc agaaaaaaga tgttatacag
   106321 ttcaagagtt acaggaaatc ttaggagtca gcagacctac tatttataac cttttaaaga
   106381 aaaaggaatt ccggtggatc cagttggatg gcggaaagta tcgcatctct aagaagagtt
   106441 tcgatgactg gctcgataac ttggaacaat aaaaaacagg gtgttgatca ggcagatttt
   106501 gtctgcaatc gacatcctaa atttttatct ggatttgaga tatgatataa gaaaaaaaac
   106561 taacactaaa aaagacagga agtgaagaat aaatggcaac agcaattatg aaacaaaaag
   106621 aagttccgga aatggacgat gttgaagaga tcatttcaaa gatatcagaa gacagtcctt
   106681 acaaacggcg tccgacacaa aagagaacct ggatgaccgt gccggaaatg ggaaagctgc
   106741 tgggattaaa aaagacagat cgatactggc tggtgcataa aaatgttttt gaatctaaag
   106801 agattgctgg aaagatacga atcaatattg ccagctttga aaaatggtac gccaatcaga
   106861 ttaaatacca taaagttacc ggagaagaac cagggaaaga attgaaatcc tggtcctatt
   106921 ccgttaagga agttgcggat ctgttgggtg ttgatgagta tcttgtttat gatttactca
   106981 agaaaaatca aatggaagct gttattgtcg attactggaa acgaatacca aaagaatctt
   107041 ttcagaactg gtataaaagc cagtcccggt atcgaacaaa ggaagacaga aaaaaagacg
   107101 ctcttctgga agatgcaaca attacgatgc ctgagatggc acagctgctt ggaacaacca
   107161 gaagcgcagt atatacaatt cttgataatc caaagtatag tcattttttt gaattcattg
   107221 tgattgcaga aaagaaaagg atcacaaaag agagttttcg aaaattcctg gaaggtcagg
   107281 atcggtataa gctggatcca tcgaatgatt atgaagaact tgcacaggaa caaaatattg
   107341 ccctggctaa tttccggcgg aagaaattat cacagaccgg aatacgagga agcaatggaa
   107401 atataaagta tcttactttt gatgaagctt cctatctggc aaaggtcagc agaagcatga
   107461 tcaacaagtg ggcggataaa ggaaagttca cagtaataaa agttggcagt cgagttagga
   107521 tccgtcggga tgaatttgag gactggatgg agcaaagaga tttggaaagg agtatgcaat
   107581 aatatggcat ctataagaga acgaaacgga aaatttaatg taatctattc ttatacgaat
   107641 gaaaaaggtg agaggaaaca gaagtgggaa acctatgaaa cgaaagccga agcaaagaga
   107701 agaaaaaaag aaattgaata taaaaaagag atgggatcat ttgtcgtccg taaatgcaaa
   107761 acactggacg agcttattac agaatatgtt gcactttatg gcaaagaaaa ctgggcgctt
   107821 tctacatatg aaggaaatgt ctctcttatc aataactata ttcttccgat cattggtgat
   107881 acgaaactct cagagatcaa tacccgtttc atcgaaagat attatcagag tcttttgaag
   107941 agacgtgcag ttatcaatcc attgaataaa accagtcgaa atgaatttgt atcttccagt
   108001 acggtcaggg atattaataa gctgcttaga aactgttttg aacaggcagt gaaatgggag
   108061 ttgatggaga agaatccttg cacccatgcg actgtaccaa aacataaatc acaaaaaaga
   108121 gacatctgga cagcggatac attgatgtat gcgctcagtg tctgtgaaga tgaacgatta
   108181 aagctcgcaa ttaatctatc tttctcatgt tccctgcgac ttggtgagct gcttggtctt
   108241 acctgggatt gtgtagatat ttctcatgag gcaattgaag aaaaccgtgc atatgtcttc
   108301 atcaacaaag aatcacagcg tataagaaaa gaatctttaa atgcattgga tggaaaagat
   108361 gtgttgttgg tatttccgac aaatcataag aagaattcta cggtccgtat tctgaaaaca
   108421 ccgaagacag aaagtagtgt acgtaagata ttcttaccga agagcgttgc taatatgctt
   108481 gtagactgga aagctgagca ggatgaaatg aaagaaatcc tgggtgacga atatatggac
   108541 tataacctgg ttatggcaag tacctttggt cttcctcttg gtgatggagc aatccgtggc
   108601 cctttaaaga aattgatcga ggactataat ctcccaccgg ttgtatttca cagttttcgt
   108661 catagcagtg ttacttataa gctgaaactg aatggtggag acatcaaggc ggtacagggt
   108721 gattctggcc atgctcaggt caatatggtt acagatgtgt actctcatat tctggatgat
   108781 gacagaagga aaaatgcaga gctttttgaa gaagcatttt atgagaaaaa gaatctggat
   108841 ccacagatgc atgtacagca ggaaaataat aatactactg ttgctgatga agtcgatccg
   108901 gaacttctgg caaaagtatt ggcgaatcca gagatgcggg cattgctcaa ttcactggcg
   108961 aagacgatga agtaatgaaa aatagtgaaa aaatagtgta attttagtga aaaaacgatt
   109021 cataaaacga tataatatat ggatgaaatg aggatattta ttgtgtatat ggatattcta
   109081 tctccatcat ttgatgatag aatgacggag ataaatctga aatgaaggag attcctatga
   109141 gagactttga ttttattgta agtcctgcga agttgttaac acctgaaatt gttcagatgg
   109201 ttagcagcat ccatgaacat aaaggcaaac aggaattatt tctcgaagcc aatgtagatg
   109261 aattgaaaac actcttagaa gttgcattga ttcagagtac gggagcatcc aaccgaatcg
   109321 aaggtatatc tactggttat gtccgtgttt aaaaatatga aagcagctta taaatttgcc
   109381 agtcaaaaac gcatggacaa accgtctcgt atgcgttata ttatttatag acaagaaaat
   109441 atcttgtact tatgatagga aagtttaatt gaatactgtt taccatgatc gaacgtacga
   109501 agcatggtgg tcatataaca gatgtcgatg gtaatatcaa ggcattcccc gattattagc
   109561 tggggcaaac aatcagctaa ctttcagagc tttacagagc ttgacagagg gggtattcag
   109621 aataactcga attgaatcgg aaacagtttt atatagtgtc ccatatgggt ttaccttacc
   109681 tcagattgac agagagtgac aataggttgg agctctccta agcgataggt cgctggttca
   109741 attccagtca ggaacgtata aataacccct gtatcctttg cggtacaggg gtttgttttg
   109801 tatttgtgcc aaaaatgtgc caaactagtt atcattttta tataaactat cgaacacagt
   109861 attgattttt tctttatcct gatcttcaag ctctcgaaca atatgaagat aagtagacat
   109921 tgtagtttct aaactgctat gtcctaaacg tttcgatacg ctaagtatat ttactccttg
   109981 ataaagtaaa atagatgcat gtgtatgcct tagtccatgc aaagtaaatt gcttttcaat
   110041 ccctaattct tttaattttt tgcgcaaata tttgctgacg gcgtttgatg aaactaatcc
   110101 attttttaag ttgaaaaaaa caaaattatg agggtttttg atttcaaaat tctcgaataa
   110161 ttctttttga ttgattttaa acttttttaa gagatcaatc gtatgtttat caatggaaat
   110221 tttcctattt gaagtttcgt tttttgtttt tccccattca tttaatttat aattccatgt
   110281 tttattaata gtgatgattt gatcttcgaa atcgatatct tcccatgtta atcctagaag
   110341 ttcagcaaat cgcattccag tggcaccagc aactaacacg agcataggag aagagtactg
   110401 cgcagaaagg ttttcttcta cgagtttcat taaagattta aattgatcat aatctaaata
   110461 tttatcttct tttggcttca atgaatcttt tcctttgatt actgcttttc tagttggatc
   110521 aaacggaatt aatccttctt ctacggcatc tttcaacgat gctctaatat ggttattaaa
   110581 cttaataacg gtggatttta catggtcttt cgcatactta tttaaaaagc gttgatatcc
   110641 aactctatct aaatcagaaa tcaataccgc tggcatatat ttctttatgt tcattaacgt
   110701 atcttcgtat tttctataag tgataggaga tactgttcct tctttataaa gttgcatcca
   110761 atcctcaaag taatctgata ataatagatt tttgcgatcc cctttaaggc ctttgttcaa
   110821 gttatattct aattcgttgg cggcatcttt tgcttcgcct tttgtcttaa atcctgattt
   110881 tcttatcttc gtgtattttc cgtcatcttt tttgtatgaa atttcgtatt gccaactatt
   110941 tccacgtttg actaatcttg ccataattga atctactctc tttctctgat acaataggca
   111001 ctataaagaa gcctactgta taggtttgtt tttcttagaa cacgcttgct ttggacggtg
   111061 ggcgtgtttt ttatttatta tacagttgct ttaaaaatag ctgctttttc aaatgatact
   111121 aaaggagaga agtggatttc tatttctccc ttttggttta acgtgaaatg agcagttaca
   111181 tccatttgtt ttcctggagc aacagatccc attgtatttt cgttggcata tgtctctgat
   111241 tttttgtcat ctggtccata tacttccaca tctgtaccta cagggatatc tgaatcgcca
   111301 tcatttttta cggtataagt aatttttact acttgtgcag gttggttttc ttcaaattga
   111361 tttctttcat cagttagttc tacactattt agtgtatatt cagcatcacc aacttttaca
   111421 gtgtcaccaa tcttatagaa ggtatcgctt ttttcttctt tagaagatga agcagaggtt
   111481 gaagatttag ttactttttc gccaccatta tcacttgctt tattactatc tgatccacca
   111541 tttaaagcag aaccaataat tataattaaa attactgcta atacccaaaa ccatactttt
   111601 ttgtaaaaag gtttactaac tttatacatt tttccgtctt gacccataac tttttttgcc
   111661 atttaaatat tcctcacttc ttgttataat atatttgcga tctcagaaat gaggtatgag
   111721 tccgtgttgc agcacgggct ttttttactg tgcataagag tattttttct tgaaatatga
   111781 ctggcaaaca ttaaaacatt ctgttcttaa cttattattg atagcataga attccataaa
   111841 attttccaat ttgaactgag attcatctgt taattcattc tcaataaaga tattaagtag
   111901 aatcataatt gcaattttat cagcttcagt ttcgaatttt gaatgaaaag ttgtagagtt
   111961 atcgtacagt actgaatatt caaaatgtga agcaatgaaa tgaccgagct cgtgggctaa
   112021 atgaaaagct tcagaactat cttcgtgtag tttttcgttt aaaaatacta ttcttggttt
   112081 tggataataa aaacctggtt cttccatttc catatagatt aactttaaat tatactcact
   112141 cagcatttct ttcaacttta aatacataca acccatcact ccaactattc attttcctct
   112201 aaagctttag caattgcaat cgctttacgc attgtctcct tagatatttc ttttccatca
   112261 aaagaaaaaa cagtatcgtc ttctgataaa tccacatgtt taggggtttc tctttcttct
   112321 ctacctagaa ggtagtctac agagactcca aagtaatcag ctaaccgagc taactcaata
   112381 gaattaggag tttgtctttt ccaacttcct aaatatccat tcgaataccc gaaattcatt
   112441 tcgagctgtc taatggataa tcctttttct tttgctaact cctttattat ttcgtaagta
   112501 ttcattgata aatcaacctt tctgaatgct tacaaaaaaa gtttagataa ataatgtaaa
   112561 aatagttgac ttatatacat tattaatcta tactatgttt tgtaaacaag tttaacaact
   112621 aaaaagacaa caaaaaatac tattgattaa taaatgccaa ccgccaagaa agctttttaa
   112681 atcaaagttt agatgtctta tttaactatg catttagtat agattattaa tctaataaag
   112741 tcaacgcagt tttttaaaaa gttgttaaat ttgtttacga atataaaaga aaggagagaa
   112801 gaatatggaa aaaacagtct cggcaaaaat cgaagatttg aaattagaca tactgaaaca
   112861 agcaaaagtg gcgatggaac acgcggtaga taaagaagac tctgccatgg ttgcagccat
   112921 agcagagatt ttagctcacg tttagtcatc gtttttacgg tcttctggaa gctgaccata
   112981 gataacagca taatgaatat ctaaataagc ttgaacaatt tcttttggcg aaattgattc
   113041 gcctttagta gatacttgtg attcgtgatt tagccatgca acaactaaat ccgcagcgat
   113101 ttcaaacggc gttacacttt gtgtcagttg ccataaagaa tttcacaata tgtatggtcg
   113161 tggtaataat accaaagagc aatttgagga atttatggaa attaaaaaat acaaaaaatc
   113221 atttattaaa ggaggctaaa caatgaacaa ggaaatgagc caaacaatca aggtacaaaa
   113281 aatgatagat gatctaacac atggaattga tagccaagcc gataaaatca tcaaggaatt
   113341 gcaaggacaa aaagttaagg atgcaaaaat gcttctcaag actatcaact ttgaaatgaa
   113401 tccaacaaaa agaaagctcg ccgatgtgtt ggaagaaaag ttggcttccg ctatcaacga
   113461 gcaagaatta ctatttgaaa ccgatacttt taacagctga tgttttatag atgacagttt
   113521 catccgaatc tatatcatcg ccgagagaaa agaatgttgc ttttgacaaa aagccgataa
   113581 gacctacaag cggtcttgat gttgcaagag tagatacccc aatatcacct tgcaaggtat
   113641 tcacgtaaat ttgagaagaa tagaacattc catctttttc ttcgatattt gacgcatcat
   113701 cgtatccaac gaccaaagta tcggcaaata ttttgatttt ttctccatca agcatagtaa
   113761 ttacaaattc tggtttcata aattttcacc tccttaacaa ttatttcagc ctgtcacact
   113821 gataaggaaa ttataccaaa gaaaggaatg agaaatatga atacaccaca aatttttaat
   113881 ttcgagcaaa acgaagttcg aactatttta gtaaatgatg aaccatattt tgtaggaaaa
   113941 gatgtagcag acgttctagg atattcgaat ccgcaaaaag ctattcgaga tcatgtggac
   114001 ttggaggata agacgcagaa cgattcgttc accgtcaatg gaacagcagt tgttttgatt
   114061 aacgagtcag gcctttacag tttaatctta aaatcaaaac ttccctctgc caaaaaattt
   114121 aaacgttggg taacgagtga agtccttcca acaattagaa aaacaggtag ctattcaaac
   114181 gtacctcaaa gttttgcaca agcattgcgt ttagcagcag atttagaaga aaagaaccaa
   114241 ttactcgaac aacaaattgc cgagtacgaa ccaaagatta gctacttaga tacgattctt
   114301 tcatcgacag atacggtagc tacttctcaa attgcagctg attacggaat gtcggcaatt
   114361 gctctaaaca aattgctaaa cgagttaggt gttcaacata aagttagcgg acaatggata
   114421 ctttaccgaa aacatatgaa ccaaggatac acaaaatcgc acacaagtga gattccgaaa
   114481 gccgatggcg gcactaaagt tgtaatgaat accaaatgga cacagaaagg gcgagtgttt
   114541 atttacaact tattaatcgc agagggctat taccctcaaa tggatttaga ggaaattggt
   114601 tagaaaggag ttttagtatg actgacattg cagaaatcac tcaacgagat agagaaaaaa
   114661 tcaaagaata tgtcgaaagt tcgaagttct taacttacac catgcttgct gaaagatttg
   114721 gaattagcaa aagctactta tctttaattt taaacggtaa aaagacttct gcagaagcaa
   114781 atagaatcat agattcgatt attactatgt acgaattgta aagggaggaa cagctaatgc
   114841 aatatctaga agcgaaaatc ccagttccag aaggctatgt aattatctcc caagtggatt
   114901 atgaggagtt aaaaaaagct gatgatactg gtagatggat gacgttgcca gaagtgctag
   114961 aacggattaa cagaaaatat gattggttta cttctagagt tttaaagaac ccaagatata
   115021 gaaatattat cgatatcgaa aaaaataaaa atggatttgt ctattatcca gttgaaggaa
   115081 gagacacata tctattttta agaagtaaaa cacttgaatt tttagaaaca aatttttcgg
   115141 aaatcttaag gaggcaagcg gatgggaaaa tttaatagag cgctagtatt cagcgcaccg
   115201 ctaatcatct acgctttagg actttgggga agcagacaag cgttgatagg aacgattgtt
   115261 tacatggttt ggatttttat ggggctggat gaagctgagt acaaaacaaa aaagccagtc
   115321 gggagggact gactaatgaa aaaaagttta atgactataa acgaaaaaca attgaaagaa
   115381 aattttaatg atctcatcaa agaatttgta aaagaaactg gagaatttcc taatcaaatt
   115441 catctagttg cggaggggca tagccagtat caagctgtga aatttgagat gaagaaacaa
   115501 atctattgaa tttagcagta cctctacttg taagaacatt tattgtaatg tttttttcga
   115561 ctaaagattc atcgtatcta aaaaccaacg tagtaatttt tgactcatac ggtggaatgg
   115621 taataggtaa tgacaacgga ggaaattttg atagatcagc accttttttt aaagatttac
   115681 cagaatacgc acgtatacca tgtggaagtt cgtcatacat tgattttacc gttacagaat
   115741 aattatcacc aatcattgta aaagcattta aatgatcagg aattccagaa atcgaaaact
   115801 caataattgt aacaggtaaa gaactgttat ttgttaacaa tacagaatct ataatcctga
   115861 atttattttg atggtaaaca tctggtttgg aatcactttc tctatctatc aaccattctt
   115921 cgcattcagc gaagaaatcc aattttaaat taaatttttt gttttttcta tctgtatagg
   115981 agatataaaa agcaaatgtt gaaaatacta gagacgtaat aggcaaaata aaatctttaa
   116041 tggttttaac aatgttattc cagtcaaatt gtttaataaa gtcaataaga ctcaatttat
   116101 accaccacca ttttttatct acattatatc aaagaggaga gaagaaataa tgcaagaatt
   116161 agtaattttg aaaaataaag aagctgtgac tacgagtttg caagtcgcag atagttttga
   116221 aaaagaacac aaaaatgttt tgagagatat tgaaaagtta aaagaagatg tgctcaattt
   116281 tgagcagatg tttgtggaag gtaatgaacc agattcatac ggcagaaatc gacgagtttt
   116341 cttcattagt agagatggtt ttttcttgtt ggctatgggt tttacaggaa agaaagctat
   116401 ttacttcaaa caaaaataca ttgaagcatt caacgaaatg gaagatgtta ttcgtaagaa
   116461 tactgttcct caaacaattg aagatatgat gatctaccaa ctagaagaaa tgaaagatgt
   116521 taaaaaagat gtttccatgc ttaaagatac tatgcgaatt agtgggcaac aagagtttga
   116581 aattaaacaa aaaggaaata taaaagttat ggaagttcta gggggtaaag aaagccgagc
   116641 ttatgaagaa atcagcaaaa aagtattctc aaaattttgg tctgaattta aacgtacctt
   116701 ttcaatccca agatatggcg agttacctcg taagagattc gatgatgctg tttcatttat
   116761 tgaaatgtgg ttaccagaaa ctgcgatccg catggaaatc gatcaactga acagacaaca
   116821 aagacttttc ggtgatgaaa atgaatagag ctgaagcgct aagaatcggg acggtaattg
   116881 ctaatcgctg gtggagacac aataaaccaa tcatcctaag ccaacaacat attgacaagc
   116941 aaaaagcatg gcaacaaata aaaaagtgac tccgccggca agcaaagagt cacaaagaaa
   117001 acacatcata aggagatttt agcatatgga aaaagaactt tccactctag atcaatattt
   117061 gactgatcct agttggggca aatcgaatat caaggaaaca aataatcgaa aaatcagacg
   117121 aaatcttttg acggatgaag aactagcatg tgatcaagac gatttgggaa attttgtgag
   117181 tatttgggat catgtctatc ttatccattt atcgaggaag tccaaaaaac ctgaatatat
   117241 ctatgtcatc gaagatggct tgattgatgc gctagaagag tatgacagag ataacttgat
   117301 tgatatctct tattacggat caggtaagaa atacattgct gaaatggagg cagaatttga
   117361 tgagtgaaaa caaagggaca acgacttttg aaaaactttt tagtcgcaag ttaaataaaa
   117421 tactcaagaa aaaaggaaat tttgattatt tatcttgggc tcacgcatgg gagattatga
   117481 aaaagaatga tccacaggca acggtaacta ttaatgagta taaacactac agagttgttt
   117541 ctggaactca tcaagacttt cttgttgagg aatataaacc ttttcttatg gatgaaactg
   117601 ggacttatgt atctgtctca gtaacggtta aaggacacac ggaaaccgaa ttatttcctg
   117661 ttttagatta tcgaaaccaa ccagttgtta cgccaaatgc tatgcaaatc aataactcat
   117721 tgaagcgatg ctttgtgaaa gcattggctc tacacggact gggattatat gtatttcaag
   117781 gggaagatat tccaacacca cctagaatcg atacaaagaa attaaacatg ctagagacga
   117841 ttctagaagc tttcaatgag cagatgggta aagatatgac caaaacctta atcgaatatg
   117901 ttaatgagca gacagataaa ttagggctct tagctgataa cgttgaaact attgaacagt
   117961 taagctatga gcaatgtgcc ttgatggagc gagcaatagc agctaagaga aaagaattag
   118021 ataagaagtg atatgagtgt ttaaaccatt aatcgattca tattcagcgg ttctgaaaaa
   118081 gttcaaagga aaagacatag gtgcaactat taatgaagaa gtgaacatcg aacgtttgaa
   118141 gacgatgtac gacggatatg atggcgatcg gattattgaa gttcgattta ttgatcctag
   118201 acgtttcact gtacagcaac gaaacttcat ctatgcgctc ataggcgata ttttcatcga
   118261 tacaggcatg ccaacggact tctggaagga attcttctac tttcgttttg aaggcgtcac
   118321 agggcgcaaa ataagcctca aagacgaatc gaatacaact gtgagtgatg ctaatgtctt
   118381 agcaaatatc atcttagatt tcatctttga acatcatatt cctttcaaag aaggctatga
   118441 gattttacca gcgaatcaag aatattactt ctacaaatgc atcacaaaaa gagtctgctg
   118501 catctgtggc aaaacaggag ctgacatcga tcactttgac aaagcgctag gaagacgaaa
   118561 gcgcaaagaa gttgatcatt cagagtacac atttgcagca ctctgcagaa tccatcacac
   118621 agagaagcac aaaataggtg tgattaattt caaaaataaa tatcaaatca aagggatcaa
   118681 attaaaccag aaaacaatca aaaagttaaa tattggaggg taaaaatgac agaacatcga
   118741 agttattatg cgattatacc agccaacgta aggtacgaca aaagacttaa accaaatact
   118801 aagttgttat acggagagat aacggccttg tgtaatgaaa gaggcttttg ttgggcaggc
   118861 aatgagtact ttgcagattt atatggtgtg aataaagaga ccatatcgcg atgggtaagt
   118921 gatttgatta agtttggata cttgaatcgg gaaatcattt acaaagaggg taccaatcaa
   118981 ataatcaata ggtacctacg aattaatcaa taccctattg acgaaaaacg caatacccct
   119041 attgacgaaa aagtcaaaga taataataca tctattaata atacatttaa taatacaaaa
   119101 gaatatataa gagagttacc gccttcgaaa aaatcgaagg ctaagcccgt ccgtcataaa
   119161 tacggagagt ataaaaatgt tcttttgtca gatgagcaga tggagaaact caaaacagaa
   119221 ttccctaatg attaccaaga gcgaatcgaa cgactgtcag agtattgtga atcatctggt
   119281 aagacttata aaaactattt ggcaactatt cgaagttggg caaggaaaga aaaaagtgaa
   119341 cctaagaacg caagcagtgg atacaagcgc acaggaagac gagagaagct tcctgaatgg
   119401 gcaatcgacc aagaagccta tctcaagaaa aaagcgctag aacgagctaa tagacaatca
   119461 aaagcaccat tctaagaggt gggaaattga aaatcgatta tctagaacta attaatgaaa
   119521 tagcaaagta taaaactggt gaggaaatag aaatcctgag agacgtatat gatcaactcg
   119581 aagaagctgg aatcgaagga attaagaatg atcgttcgag ttggagtaag ctcagatact
   119641 atttcgcact ttatatcgat acaacacaat taagaaattt agcatatacc aaattactat
   119701 ttgttgattg tgttaaaggc ttgcaaaaac atcttaatga acttgagcag gtgtaatcag
   119761 atggacctaa agacatttac agcacagatt gaactaatgc atcaagaagc tttaagacaa
   119821 agtgtatcgt acgaagacaa gtggctcaac acgttccacg gcggacgtga gagcgcactt
   119881 gatcaagtac tcaaattact gaaaggagaa tgtcgggatg gataagaaag cggcaatgca
   119941 gcgaattatc gaattgactt attcagaaga ttggcaaaat gacaaagaag ctgcttcaga
   120001 agtgatgagg cttggaagag cgatgtgggc agacaagagc aacaagccaa gaccacgaaa
   120061 aatcgcaatt tggcacggtg acaaacttct agtgataggg acagctgaac agttagcaag
   120121 tctcacaggc ttgcacgaga aaatcgtgag gaaaagagca aggtgtggct acacagacgc
   120181 taagaagaga acgtttagat acgtggagga atcatcatga caacagaaga agtgattcaa
   120241 atgcgtattc gaagccttca gcgtgagatt gacgatctgg aacgaacaaa ggcagtgatg
   120301 gtcaatgaaa cggcgagaaa ggcaatcgat ttgcacatag agaatttaag aagggaaatc
   120361 catcgattgg aggaatgagc gtggataaga aagcagcaat gaaaagaatt gctgaattaa
   120421 ccaagtcaga atcttggcaa gaagacaaag aaatagttgc agaagtccaa aagctcggta
   120481 aatcaatgtg gactgaaaag cccaaacgga gaacgccgag aaaaattgca atctggcatg
   120541 atgaccgaat tttagtaaca ggtactgctg aacagttatc tgaaattact ggattaagca
   120601 aaaacattat ctgggataga gctaggagct tatggattga ttcaaaagga cgacagttta
   120661 ggtatgtgga ggagagataa tggatctcat tacacaatac agtgacatca tcctcaagaa
   120721 aatcatgatg aagattcaga aaga
//
LOCUS       DAFENC010000003       108873 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.003, whole genome shotgun sequence.
ACCESSION   DAFENC010000003
VERSION     DAFENC010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 108873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 108873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..108873
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.003"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(104..814)
                     /locus_tag="LP493_000258"
     CDS             complement(104..814)
                     /locus_tag="LP493_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HBL2132439.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(811..2283)
                     /locus_tag="LP493_000259"
     CDS             complement(811..2283)
                     /locus_tag="LP493_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBL2132440.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            2421..2894
                     /locus_tag="LP493_000260"
     CDS             2421..2894
                     /locus_tag="LP493_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBL2132441.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(3047..3598)
                     /locus_tag="LP493_000261"
     CDS             complement(3047..3598)
                     /locus_tag="LP493_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBL2132442.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            3703..4233
                     /locus_tag="LP493_000262"
     CDS             3703..4233
                     /locus_tag="LP493_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HBL2132443.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(4716..5159)
                     /locus_tag="LP493_000263"
     CDS             complement(4716..5159)
                     /locus_tag="LP493_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2132444.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(5175..6335)
                     /locus_tag="LP493_000264"
     CDS             complement(5175..6335)
                     /locus_tag="LP493_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL2132445.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            6842..8542
                     /locus_tag="LP493_000265"
     CDS             6842..8542
                     /locus_tag="LP493_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132446.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(8644..9477)
                     /locus_tag="LP493_000266"
     CDS             complement(8644..9477)
                     /locus_tag="LP493_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBL2132447.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(9781..11946)
                     /locus_tag="LP493_000267"
     CDS             complement(9781..11946)
                     /locus_tag="LP493_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL2132448.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            12206..14500
                     /locus_tag="LP493_000268"
     CDS             12206..14500
                     /locus_tag="LP493_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBL2132449.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            14493..15158
                     /gene="pgmB"
                     /locus_tag="LP493_000269"
     CDS             14493..15158
                     /gene="pgmB"
                     /locus_tag="LP493_000269"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBL2132450.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            15151..16158
                     /locus_tag="LP493_000270"
     CDS             15151..16158
                     /locus_tag="LP493_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBL2132451.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            16180..17199
                     /locus_tag="LP493_000271"
     CDS             16180..17199
                     /locus_tag="LP493_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2132452.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(17480..18847)
                     /gene="nhaC"
                     /locus_tag="LP493_000272"
     CDS             complement(17480..18847)
                     /gene="nhaC"
                     /locus_tag="LP493_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBL2132453.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(18956..20377)
                     /locus_tag="LP493_000273"
     CDS             complement(18956..20377)
                     /locus_tag="LP493_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2132454.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(20620..22497)
                     /gene="tdc"
                     /locus_tag="LP493_000274"
     CDS             complement(20620..22497)
                     /gene="tdc"
                     /locus_tag="LP493_000274"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBL2132455.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(22788..24044)
                     /locus_tag="LP493_000275"
     CDS             complement(22788..24044)
                     /locus_tag="LP493_000275"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HBL2132456.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(24156..24361)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            24624..25925
                     /locus_tag="LP493_000276"
     CDS             24624..25925
                     /locus_tag="LP493_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBL2132457.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(25994..26593)
                     /locus_tag="LP493_000277"
     CDS             complement(25994..26593)
                     /locus_tag="LP493_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL2132458.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            26847..27728
                     /locus_tag="LP493_000278"
     CDS             26847..27728
                     /locus_tag="LP493_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2132459.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            27741..29351
                     /locus_tag="LP493_000279"
     CDS             27741..29351
                     /locus_tag="LP493_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HBL2132460.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(29428..30087)
                     /locus_tag="LP493_000280"
     CDS             complement(29428..30087)
                     /locus_tag="LP493_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBL2132461.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(30370..31035)
                     /locus_tag="LP493_000281"
     CDS             complement(30370..31035)
                     /locus_tag="LP493_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HBL2132462.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(31182..31787)
                     /gene="dhaL"
                     /locus_tag="LP493_000282"
     CDS             complement(31182..31787)
                     /gene="dhaL"
                     /locus_tag="LP493_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HBL2132463.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(31815..32825)
                     /gene="dhaK"
                     /locus_tag="LP493_000283"
     CDS             complement(31815..32825)
                     /gene="dhaK"
                     /locus_tag="LP493_000283"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HBL2132464.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(32800..33246)
                     /gene="dhaM"
                     /locus_tag="LP493_000284"
     CDS             complement(32800..33246)
                     /gene="dhaM"
                     /locus_tag="LP493_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HBL2132465.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            33349..33669
                     /locus_tag="LP493_000285"
     CDS             33349..33669
                     /locus_tag="LP493_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HBL2132466.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(33781..34650)
                     /locus_tag="LP493_000286"
     CDS             complement(33781..34650)
                     /locus_tag="LP493_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBL2132467.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(34746..36050)
                     /locus_tag="LP493_000287"
     CDS             complement(34746..36050)
                     /locus_tag="LP493_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL2132468.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(36047..36556)
                     /locus_tag="LP493_000288"
     CDS             complement(36047..36556)
                     /locus_tag="LP493_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132469.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(36731..38866)
                     /locus_tag="LP493_000289"
     CDS             complement(36731..38866)
                     /locus_tag="LP493_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL2132470.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(38949..40604)
                     /locus_tag="LP493_000290"
     CDS             complement(38949..40604)
                     /locus_tag="LP493_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL2132471.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(40606..40920)
                     /locus_tag="LP493_000291"
     CDS             complement(40606..40920)
                     /locus_tag="LP493_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBL2132472.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            41090..41350
                     /locus_tag="LP493_000292"
     CDS             41090..41350
                     /locus_tag="LP493_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HBL2132473.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            41364..41678
                     /locus_tag="LP493_000293"
     CDS             41364..41678
                     /locus_tag="LP493_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HBL2132474.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(42408..42962)
                     /locus_tag="LP493_000294"
     CDS             complement(42408..42962)
                     /locus_tag="LP493_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBL2132475.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(43088..45017)
                     /locus_tag="LP493_000295"
                     /pseudo
     CDS             complement(43088..45017)
                     /locus_tag="LP493_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(45323..46039)
                     /locus_tag="LP493_000296"
     CDS             complement(45323..46039)
                     /locus_tag="LP493_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBL2132476.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(46040..47863)
                     /gene="glpO"
                     /locus_tag="LP493_000297"
     CDS             complement(46040..47863)
                     /gene="glpO"
                     /locus_tag="LP493_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HBL2132477.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(47877..49373)
                     /gene="glpK"
                     /locus_tag="LP493_000298"
     CDS             complement(47877..49373)
                     /gene="glpK"
                     /locus_tag="LP493_000298"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBL2132478.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(49509..50969)
                     /locus_tag="LP493_000299"
     CDS             complement(49509..50969)
                     /locus_tag="LP493_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2132479.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(50959..52254)
                     /locus_tag="LP493_000300"
     CDS             complement(50959..52254)
                     /locus_tag="LP493_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL2132480.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(52586..53263)
                     /locus_tag="LP493_000301"
     CDS             complement(52586..53263)
                     /locus_tag="LP493_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HBL2132481.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(53293..54384)
                     /locus_tag="LP493_000302"
     CDS             complement(53293..54384)
                     /locus_tag="LP493_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HBL2132482.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(54485..54919)
                     /locus_tag="LP493_000303"
     CDS             complement(54485..54919)
                     /locus_tag="LP493_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL2132483.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(55503..56960)
                     /gene="ascB"
                     /locus_tag="LP493_000304"
     CDS             complement(55503..56960)
                     /gene="ascB"
                     /locus_tag="LP493_000304"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBL2132484.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(56957..58852)
                     /locus_tag="LP493_000305"
     CDS             complement(56957..58852)
                     /locus_tag="LP493_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL2132485.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(58910..60685)
                     /locus_tag="LP493_000306"
     CDS             complement(58910..60685)
                     /locus_tag="LP493_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBL2132486.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(60735..62231)
                     /locus_tag="LP493_000307"
     CDS             complement(60735..62231)
                     /locus_tag="LP493_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL2132487.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(62425..64047)
                     /locus_tag="LP493_000308"
     CDS             complement(62425..64047)
                     /locus_tag="LP493_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBL2132488.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(64375..65688)
                     /locus_tag="LP493_000309"
     CDS             complement(64375..65688)
                     /locus_tag="LP493_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBL2132489.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(65933..66157)
                     /locus_tag="LP493_000310"
     CDS             complement(65933..66157)
                     /locus_tag="LP493_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132490.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(66177..66599)
                     /locus_tag="LP493_000311"
     CDS             complement(66177..66599)
                     /locus_tag="LP493_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HBL2132491.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(66741..67451)
                     /locus_tag="LP493_000312"
     CDS             complement(66741..67451)
                     /locus_tag="LP493_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132492.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(67469..67966)
                     /locus_tag="LP493_000313"
     CDS             complement(67469..67966)
                     /locus_tag="LP493_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2132493.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(68003..68455)
                     /locus_tag="LP493_000314"
     CDS             complement(68003..68455)
                     /locus_tag="LP493_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL2132494.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(68590..69195)
                     /locus_tag="LP493_000315"
     CDS             complement(68590..69195)
                     /locus_tag="LP493_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBL2132495.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(69645..70265)
                     /locus_tag="LP493_000316"
     CDS             complement(69645..70265)
                     /locus_tag="LP493_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBL2132496.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(70267..71136)
                     /locus_tag="LP493_000317"
     CDS             complement(70267..71136)
                     /locus_tag="LP493_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HBL2132497.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(71159..71566)
                     /locus_tag="LP493_000318"
     CDS             complement(71159..71566)
                     /locus_tag="LP493_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBL2132498.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(71585..72874)
                     /locus_tag="LP493_000319"
     CDS             complement(71585..72874)
                     /locus_tag="LP493_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2132499.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(72901..73203)
                     /locus_tag="LP493_000320"
     CDS             complement(72901..73203)
                     /locus_tag="LP493_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2132500.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(73228..75321)
                     /locus_tag="LP493_000321"
     CDS             complement(73228..75321)
                     /locus_tag="LP493_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBL2132501.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(75810..76574)
                     /locus_tag="LP493_000322"
     CDS             complement(75810..76574)
                     /locus_tag="LP493_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HBL2132502.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(76685..77554)
                     /gene="mdcB"
                     /locus_tag="LP493_000323"
     CDS             complement(76685..77554)
                     /gene="mdcB"
                     /locus_tag="LP493_000323"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HBL2132503.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(77579..78655)
                     /locus_tag="LP493_000324"
     CDS             complement(77579..78655)
                     /locus_tag="LP493_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HBL2132504.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(78679..79272)
                     /locus_tag="LP493_000325"
     CDS             complement(78679..79272)
                     /locus_tag="LP493_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HBL2132505.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(79276..80952)
                     /gene="mdcD"
                     /locus_tag="LP493_000326"
     CDS             complement(79276..80952)
                     /gene="mdcD"
                     /locus_tag="LP493_000326"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HBL2132506.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(80942..81241)
                     /locus_tag="LP493_000327"
     CDS             complement(80942..81241)
                     /locus_tag="LP493_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HBL2132507.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(81343..82989)
                     /gene="mdcA"
                     /locus_tag="LP493_000328"
     CDS             complement(81343..82989)
                     /gene="mdcA"
                     /locus_tag="LP493_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HBL2132508.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(82996..83907)
                     /locus_tag="LP493_000329"
     CDS             complement(82996..83907)
                     /locus_tag="LP493_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBL2132509.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            84027..84884
                     /locus_tag="LP493_000330"
     CDS             84027..84884
                     /locus_tag="LP493_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL2132510.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(85071..85433)
                     /locus_tag="LP493_000331"
     CDS             complement(85071..85433)
                     /locus_tag="LP493_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HBL2132511.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            85779..87218
                     /locus_tag="LP493_000332"
     CDS             85779..87218
                     /locus_tag="LP493_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2132512.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(87225..89777)
                     /locus_tag="LP493_000333"
     CDS             complement(87225..89777)
                     /locus_tag="LP493_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HBL2132513.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(89891..91222)
                     /locus_tag="LP493_000334"
     CDS             complement(89891..91222)
                     /locus_tag="LP493_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2132514.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(91188..92666)
                     /locus_tag="LP493_000335"
     CDS             complement(91188..92666)
                     /locus_tag="LP493_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2132515.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(92971..94806)
                     /gene="tdc"
                     /locus_tag="LP493_000336"
     CDS             complement(92971..94806)
                     /gene="tdc"
                     /locus_tag="LP493_000336"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBL2132516.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            95276..96703
                     /locus_tag="LP493_000337"
     CDS             95276..96703
                     /locus_tag="LP493_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2132517.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(96795..97160)
                     /locus_tag="LP493_000338"
     CDS             complement(96795..97160)
                     /locus_tag="LP493_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBL2132518.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(97157..97522)
                     /locus_tag="LP493_000339"
     CDS             complement(97157..97522)
                     /locus_tag="LP493_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBL2132519.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(97714..97962)
                     /locus_tag="LP493_000340"
     CDS             complement(97714..97962)
                     /locus_tag="LP493_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132520.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            97961..98089
                     /locus_tag="LP493_000341"
     CDS             97961..98089
                     /locus_tag="LP493_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HBL2132521.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            98146..99840
                     /locus_tag="LP493_000342"
     CDS             98146..99840
                     /locus_tag="LP493_000342"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HBL2132522.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            99844..99963
                     /locus_tag="LP493_000343"
                     /pseudo
     CDS             99844..99963
                     /locus_tag="LP493_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            99940..100236
                     /locus_tag="LP493_000344"
     CDS             99940..100236
                     /locus_tag="LP493_000344"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132523.1"
                     /translation="MQAFEHRLPRGCEKAALHQVIRTPKLKLLLMFLTWLDLLPQMQA
                     FEHHLPRGYEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQAFEHRLPRGYEKGV"
     gene            100614..101747
                     /locus_tag="LP493_000345"
     CDS             100614..101747
                     /locus_tag="LP493_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HBL2132524.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            101778..102098
                     /locus_tag="LP493_000346"
     CDS             101778..102098
                     /locus_tag="LP493_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HBL2132525.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(102127..102591)
                     /locus_tag="LP493_000347"
     CDS             complement(102127..102591)
                     /locus_tag="LP493_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2132526.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(102722..103975)
                     /locus_tag="LP493_000348"
     CDS             complement(102722..103975)
                     /locus_tag="LP493_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2132527.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(104004..104321)
                     /locus_tag="LP493_000349"
     CDS             complement(104004..104321)
                     /locus_tag="LP493_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBL2132528.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(104347..104667)
                     /locus_tag="LP493_000350"
     CDS             complement(104347..104667)
                     /locus_tag="LP493_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2132529.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(105131..106546)
                     /locus_tag="LP493_000351"
     CDS             complement(105131..106546)
                     /locus_tag="LP493_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL2132530.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(106563..107879)
                     /locus_tag="LP493_000352"
     CDS             complement(106563..107879)
                     /locus_tag="LP493_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2132531.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(108029..108727)
                     /locus_tag="LP493_000353"
     CDS             complement(108029..108727)
                     /locus_tag="LP493_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBL2132532.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
BASE COUNT        31955 a        22867 c        18832 g        35219 t
ORIGIN      
        1 agcccaatca gatgaaaaat atggagtgct atttttatct gattgttctt actgcttgat
       61 gcagagcagc tttttcacaa cctcctacat ggtgttcaaa atattattcg ccttttgctt
      121 ctttcactaa ttttgcgaat gcttgttgtt ggaattcagc agctaaggct ttcgtacgtt
      181 gttcttgctc tgctttgctc atttttggat tttcagtcat tgcttttacc ataccgtctt
      241 gaacataagc ttttgcttca ctttccatcg tactttgctg tttcttcact aattcagcta
      301 acttggctgc ttggtccgta cttaattcta cccatgtctc tgggattttg aatgtattca
      361 ctcggctgtc atattcgtga ttgttatcag caatattgaa ccagaattta tacatgtcgt
      421 ttttgtattc ccaataagta gttttcgtca ctttttcagc atcgccgtct gtcttttcta
      481 ctttatttgt ttcgttatcc gtaccagttg cttttggttt ttcttgtttt tcatttgttc
      541 ggtaaagata cactttttct tttccattcc ctaaagcttt atacaaaagc atatctgctc
      601 cttgggaatc agcactggaa acaatttttt ctgtttttgt ttccgttact ttttccattc
      661 caaagtgatt ggacaaatta gcgacgatca aacttagtga agcgacgaag attagtccga
      721 aaatcaaaga taaaaaggtt tgccatgttt ttttagcgaa cacgttcgtt aaagcaaaag
      781 caagcaagct gacaatcaaa actccaataa tcatgcatta tcccccgctt tcattagaac
      841 aggttctttt ttcttcaata aaaaggcaat aataaagcca agaatcccaa agatgatcgc
      901 tacgataaac gcggcatggt aacctgacag tgtggcattg attgcctgat ctttataagc
      961 taatggcgta ttatccaata cagatttgct tgggatattt gcttttgtca cattcgtcaa
     1021 cacactgatc aaaatagctg taccaatcga gcttgcgatt tgacggaatg tattatttac
     1081 cgctgtccca tgactgatca agttatttgg caatgcattc ataccagaag tcgttaccgg
     1141 catcatgacc atggagatcc caaacatacg gatcgcataa aggatcacga tatataaaac
     1201 tggagtcgtt tttgtcaaga aagcaaatgg tgcagttgcc gctgtcaaaa tgaacatccc
     1261 tgtgatggct aaacgtttcg cgccgtattt atcgaaaatc gcacccgtca caggcatcat
     1321 agcccccatg atcaatgcac ccggcaacaa catcaagcca gaatggaatg ctgattctcc
     1381 acgaatattt tgaatataca atggtacgac catttctgcc cctaccatcg ccatatttgt
     1441 tacaccagct aaaacagctg caatcgtgaa tgtagatgat ttgaatacac gaagttccaa
     1501 gaatggatgt tccaaatgta attgacgcca tgagaacaag gcgatgaaaa tcacaccaac
     1561 aactaagaaa ccaattactt tcaagcttcc ccagccgtca tctcctacac tagaaaatcc
     1621 gtaaagtaaa ctaccgaatc caatcgttga taaaatagcg gataaaatat caatgctagg
     1681 atttgacaat ggaataacac ttttcattag gaagaatgct aaaaccaaga caagaacaac
     1741 gattggcagt accataccaa acaagtcacg ccaatggtag ttatcaatga tataaccaga
     1801 taatgtaggg cctaaagcag gagcaagtcc aataacgatc cctgacatcc ccattgctga
     1861 tcctcttttt tctggcggga aaatagatag catgatattt tgcaataatg gcatcgatac
     1921 tcccacaccg caagcttgga tcaaacgacc gattagtaat gtactaaaat taggtgctgt
     1981 aaagcaagta atcgttccga tcaaaaagat cgtcatggca gaaagatata aatttcttga
     2041 actgaattta ttgatcagcc atgctgttat tgggatcatg atcccgttga ctagcaagaa
     2101 accagtcgtt aaccattgca catcagacgc tgaaatatcg aaagctttca tcaatgtagg
     2161 aaaagctgtc gtcaataagg tctgattcaa aacggtacaa aatgtaccaa ttaataagac
     2221 aacaactaaa agtgtccgat tatatggttt tccgtaaata tctacgggtt ggttgttact
     2281 catatttctc cttctttctg aattttttct gaaactacta gaatacttta gtcctaaatt
     2341 cgctatttgt caacctactt gacacataag ttaatacgga tataattaag ggaagcaaga
     2401 ggacaaaagg agtgacaaaa atggttgggg cttcccttaa acgtttgttg gaaaatgatc
     2461 aattggttgt tggcatcagt gaattaagtg atatcgtagg tgtgtctcca cgtcaattaa
     2521 ggtattggga acaaaaggga ttcattcgtt cgatcgaagc tgatgcgaat tgtcctagaa
     2581 aatatcgttt acctacagtc ataaaagtag aactgatcaa aaaatattta gatgacggat
     2641 ttactttgtc aaaagctgca gaaaaggcag aaatccgcca aaagaaaatg caccatgtcc
     2701 gtaaagtttt ttcaaaagca atcaaagata tcgaattgat cgacgaacgc tatacgattt
     2761 tacaaatcgg taacttcaaa gaagagaatg ctaagatgta catcattcat gacaacgaga
     2821 cagacgaatt aacttacaag ctccttcctg tcgatgaaaa agctgactac gaacagttgt
     2881 taaaagaact ctaaacgcca ctaatctcct aagtaccaag ctttttaata agtagatgct
     2941 acataaatac ttgaaaaaag gcctgtttga acataagaat atccgaacgg tgatctgcgt
     3001 ttctttcata tagaaaggaa ttctccatca ctgttcggat atttttttat ttttttcggt
     3061 tactttcttc taatacatct gttagccaat ttgcatattc tgtttcccga ttgatcgcat
     3121 gcgctaaaat caggtagtgt ccgtaatttt catgtttttc tttttcagta ggaaagatcg
     3181 ttttttttcg ctctaataga tgaagtcgtt tttcttcatg aaggtcacgc tgctgctgaa
     3241 taatttctac taatgccgga tcattcacgt ctttgacgaa atacaatttc agaacaaatt
     3301 cgtctcgatt aaccggtagt tcattggtgg gtgtatgaat ccactctgcc aattgttcct
     3361 tcccttcttc tgttaattca taaactttct tttccaattt ttcacctgtg atctctactt
     3421 gatgctgaat gattccttgc tcttccattt ttgcaagttc aggataaatc tgactatgtt
     3481 ttgcttgcca aaattctcct atttcatttt tgaacgattg attcaattca tatcctgtca
     3541 tcttcttctt acttaataac cctaacaaaa tatatcgaag tgtatttttt cttgccatca
     3601 gttttccctc cttgacaaat ctttaaatcc attctatcat aaatgagtaa tcgaaaacat
     3661 gtagtttatt acatgtttta atttataagg agatgcttaa acatgaaaga atttaaagaa
     3721 ttggaagatt ttattggaac tcactttatc tatacgtatg acaatggttg ggaatatgaa
     3781 tggtatgcca aaaatgacca tactgttgat taccgtatcc atggcggaat ggtcaaaggc
     3841 cgttgggtaa aagaccaaga agctgatatc gttaaattga cggacggcgt attcaaaatc
     3901 acttggacag agccaacagg gacagacgtg gcattggact ttatgccaaa tgaaaagaaa
     3961 cttcacggaa tgatcttttt ccctaaatgg gttgaagaac atccagaaat cactgttact
     4021 ttccaaaacg aacatatcgc agaaatggaa gcagctcgtg aaaaatatga aacttatcca
     4081 aaattacttg ttcctgaatt tgctacgatc acttatatgg gtgatgcagg tatagacaat
     4141 gaagatgtta ttagcgaaga accatacgat ggaatgccag atgatatccg tagcggaaaa
     4201 tacttcgatg aaaattataa acgagtaaaa taaggttgtg aaagagaggt tgtgaaatca
     4261 gcgttctgac ctgagtatta gagaaagaaa cggaaaaata gttcctcatg ttttgccgtt
     4321 ttttgagcta ataccgaggg tcagctgatt gaacaccgtt tatcaagagg ttgtgaaatc
     4381 agcgttatgc tttgagtaat aagaacgcta gttagaaaat agcttttcat attttctagg
     4441 ctagtgggct tattaccgag aagcagccgt ttgaacaccg tttatcaaga ggttgtgaaa
     4501 tcagcgtttt gacctgagta ttagagaaac aaatggaaaa atagttcctc atattttgcc
     4561 gttttttgag ctaataccga gggtcagctg attgaacacc gtttatcaaa gattgtaaca
     4621 actgcatatt cacacagtta aattagtgac ttcaaaatga aataatgctc ccagcaaaaa
     4681 attaggctgg gagcattatt tcgttattct gttcatcaaa aatcagcgtt ttgattccat
     4741 ttcatcacaa gttcctcctc atttactgct tcatcttttt gctgtgtttg aattgtaaaa
     4801 ccttgtgaaa gatagaaatg aatagctgat tgattttttt gatagactgt caaagtcagt
     4861 gttttattgg tttcttttat ttttttcatt agttgcgtac cgattctttg ttgccggtat
     4921 tcccttttca caaagattcc tgcgataaac tgatcaatca ccccagcaaa accaataatt
     4981 tcttgatcta tttctgctaa gtaaatcact gcatctggta aagctttcct aacagattct
     5041 acttgattct cccaataagt tgatggaatg aattcatgag aatccaagtt agcatgcagc
     5101 caaatcgata gaacagattc cagttctttg gcagacaatt ttgttgttgt gcggatcatt
     5161 ttttctctcc ttacttattc attgatttta aaataaaaac catttttttg aagctctttt
     5221 acaagttttc gcccctcaaa aaagtatatc ttctcttgtt ttacttttct aataccaaaa
     5281 gaaacagcaa ctttaggatc atcagctgaa acgattcgat aagttccacc aggcaattga
     5341 tccagcttga ctttcccatg atggtcgctt tgtactgaaa acggcacacc atttctagta
     5401 agtgtttttt tcttatgttt caaaatgaat gaactaccat ttaccggttt ccctgacgaa
     5461 tcactaataa taaatgaaaa atcaagcact tttttactta atctatactg atagattagt
     5521 cgtccgataa acactaacag tatgactaca gctattatcg ttcctgcaag aataaaccat
     5581 tgccgcatgg ttctttcctg atttcctttt ccttcttctt tttttaccga ttcgttataa
     5641 ggaatccgat gtcctgtcac tagcaaacga tgcgtgttga tcatatacgg cgtacatgta
     5701 agcaaggtaa ctaagtcttc tccttctgaa atcgttagaa cagacgtgtc atctggcagt
     5761 accacttgta tatttttaac ttgataagcc aatttctccc ccaaaacagt caaaataaac
     5821 gtgtctccgt tttctaaacg atctaattcg gtaaataacc gtcgattagg taaaccgctg
     5881 tgagcagaga tcactgaatg cgtcgaattt ccaccaagcg ggaaagaggt tccttgcaag
     5941 acgcctgctc cattttcaag gatcctacca ttgagccgat cataaagtga aatatttaat
     6001 tggatcttag gtatattgat acttccgatc agccattcct ctaattggct ggatgttgta
     6061 ctttcatttc tgttcttttc attgaaagga tcagtaccag gattgaatcc ttggtcagtt
     6121 aatcgttggt ttttctcctc cattttcttt cgctgcactt caatttcagc tgcggtccgt
     6181 ttttgtactt gttcgatacg tttttgatca ataaaactat ttaaagaatc cacataaaat
     6241 ggatataaag cgatcagtaa ccctacgacg atacatatta ataaaaacaa acgaaacaaa
     6301 agtcgacgag actgtttttg cttactctgc ttcacatgtg tcctcccttg caagtttttt
     6361 tgttctttct tttattatat gggttcagga aaaaaataga aaatgaaagc cgatgaggtt
     6421 gtgaaaaagc tgtcctgcat caagtaataa gtacagccca aaaaaatagc tactcatatt
     6481 ttttgttggg ttgggcttat taccgcagat gcaagctttt gaacaccgtt taaggaagag
     6541 gttgtgaaaa ctgcgttatg ctttgagtaa taagagcgct agtcagaaaa tagcttctca
     6601 tattttctag gctagtgagc ttattaccga gaagcagctg attgaacacc gtttaccgag
     6661 aggtcatgaa aaagctactt tgtttcgagt attaagaaaa attctgtttc aaaacaagga
     6721 gatgcaacaa aacttatgtc gcatcctctc tccttagaac tttcacttat gtttttcttg
     6781 taaaattcat aaatattttc atgaattttc taatttcttg cctacctctc gcataggata
     6841 tatgatgaat ttatctaaag tttgcaaagg agttcgacaa ttgaaaaaat atggcccatt
     6901 tttagcaatt tttttcattg ctttggcatt tctcatgcct catttattca cacataaact
     6961 aattttgggt gctgatgccc cattccatta caatcggttc tatgatgccg cgcaacaaat
     7021 taaatatggg gatttccatt attttccttc cctttatgga ttccagcaaa gtggcaggat
     7081 cgtgaatgcc gtttacggcc catttttcgc ttatttacaa ggattgatcg tgttgcttgc
     7141 aggtagctgg tttcattatc agattctttc aaatttcatt ctttatctta tttcaggatt
     7201 ttctatgctg attttactga gatatgtcaa tgttcgaaat tgggtaagtg taccagtagc
     7261 cgttttattc atgagtacgt attctattca atactggtct atcaaccaag gattcactag
     7321 ctgggggact tgtttttatc ctttatgtat gatccctatt gctgatttcg tccttcataa
     7381 aaagttccct gttatcaaag tcgctgtctc agtgggactt atgacacaga tccatttact
     7441 gtcttcgatc atgttagctt tgatgtatat ccctttttat ctttattact tttttaacca
     7501 gactgaaaaa ggaaaagcac tgcttcaact gattaagtcg gtcttgcttt attttgttct
     7561 gacagcaaat atttgggcag gattagctat tgtttacagt gggaataaga ttcttcctcc
     7621 ctttgttaac agagaaatga gtcaaaaggc gatagatctg gatggcagtt attggctcca
     7681 ttaccctaag gcctttccta tattgatatt atcaggtttt ttgcttttta ttttctttca
     7741 acaaaagaac accttattcc aaaaaatcgt gttgtacaca agtcttgttt tcttttttct
     7801 ttctactagc ttgattccat ggacgacatt gatcgaaaaa aatgtgcctt ttattagttt
     7861 gatccagttt ccatttcgat ttttcgtgcc atttacgcta ttgcttctac tttaccttgc
     7921 cctttcactg aaccagtggt ctgaacaaaa gtggttccgt cttttaagta tatttggcat
     7981 tcttattttt tcagcacaga cgatccagaa cttataccag catctggaaa agtgggaaaa
     8041 tgaaacattt gtcagtcgac atacttatct attcgatacg ccggaagaag caaggaaaac
     8101 attcttcagc aaagatatgt ctaccagctt gttcgttttc caaaaaacca cacctgacta
     8161 tctgccaatc tataaggaga caaaagacaa taaatacgac cggtataacg aagaaatact
     8221 agaaaacgaa acaactttta taaaaacaca tccaggcggt cttttgacaa tcaagtggaa
     8281 aaacactggg gacaaaactg ttcatatccc tgttatcgtc tacgatcgga ctgtgctaca
     8341 gcaaaatgga aaaacattga ctgattatga agtaacagat atcgggaccc caatcgtgaa
     8401 gcagcaaaaa ggaatcaacg agctcacgct tcattatcaa acgccaatct atttctattt
     8461 cattctttct cttactttga ttggctggtt taccttgcta tgtttattta tttatcatag
     8521 atacaagctt ttacgtgctt aggcaaaagg gataaataca tccgatcaaa aaactctcca
     8581 aacggtataa tcgtttggag agttttattt taatcagttt ttttatgtta tatgttatat
     8641 tttttattcg ttcacatcta attcgatttc caccccgtag tgatcactga tgattggact
     8701 atcgatccca tcaaaaatcc gttgatattt tttaacctgc attccttcag ggacgaaaat
     8761 aaaatctata cgcaattttt ctgtattttg ttcccaacca tctattttct tttccacagt
     8821 agctgctttt cctttttcat tcgcgacaac atacgaatct tgaagaagaa ggcaactttc
     8881 tcttacagta taataacctt gagagtctac tggattattg aaatcaccta ggaaaaaaag
     8941 tggtacgcga gtttccaaaa agtagttttc caagtttttc cactcaaaat aaaagccact
     9001 ttttttatct gtccaccaag aaaagtggca gctcgagaca aaaatgtcct gatcatctat
     9061 ctttgttttc ccaatcaaga tcttgcgtgt ctgataatct tctttctttt gaaattggga
     9121 gacggtaagg acctgacttt ccaatgtttt tttcgtaagc agtgcatttc cttcttcata
     9181 tttatcataa ccgatgtggc tcatttccca actccaaaaa tactcttttc cgtgttcctt
     9241 taaaagctga actaaacggt aggcaaaatt atctttacgg ataggtactt gattctttac
     9301 cggacagaac ttcattagct tcgcaggttc tacttcttca gattccagta attggttgat
     9361 ttcttgtaaa gcaatcactt cataatcttc taacaggatc ttatctgcta attcttgcaa
     9421 ttttttctct ggttctggct caagccagct atgcgtgttg agtgtcatga atttcattgg
     9481 ttttctcctt gtcttcattt cgaaacaaaa gggttgtgac aaaatttttg tcacaacctc
     9541 tccagcaaat agtgttctcc tgctaactcc tcagtaataa gctcaatgga ccaggagcta
     9601 ttttttgttt ggctgttttt atcacttggt gcagggcagc tttttcacga cctctccact
     9661 aaacagtatt caaactgctg cttctcggta ataagcccaa ccaaacgaaa aataggagga
     9721 gctatttttg tttggctgtt cttatgactt gatgcaggac agctttttca caacctctcc
     9781 ttacatttta atggagccga tcactttacc agctgtcact gtacctaatt gcttgatcac
     9841 tacttcttct actttatcgt ttgtaaatac gatcatgatc gttggatctt tttcttcgtt
     9901 ttggatcaca tcaagatcca tctcagctaa tttcgttcct gttcctactt cttggccttc
     9961 tttgacagca atctcaaaag ctggctgatt catttggact gtatcgattc ccatatggat
    10021 caaaacttcg ataccatctt tcgtttccag cccaattgca tgtttgctag ggaaaatact
    10081 tgtcactttt ccagcgatcg gcgcaacaac ttctcttgat gttggaataa cagcaaagcc
    10141 gtcacccatc attttttgtg agaataccgg atcttttact tcagataaag gaatcacttc
    10201 tccagaagct gcggaaacta gttcttgttc tatacctaag tattgcttac tacctgcttg
    10261 tccatttcct gtagaaacca tttctggctc tggaatctct gctcctgatt gcagcagatc
    10321 ttcgatatct gatttcaaga catctgcttt tggtccataa actgcttgga ctccattgtc
    10381 tttgacgatc aatcccatcg cccctgctcg tttccaggct tcttcagtcc ctactttttc
    10441 tcgatcattt acacttacgc gtaaccgagt catacaagca tcgacatctt tgatattttc
    10501 ttttcctccc agcaaatgaa tgatctggac cacttgctga tctgctgttc ctgttccgct
    10561 gttagataca acggtttctt cactgtcatt gtcgtaattt ccgttacgtc ccggtgtagc
    10621 aaagttgaat tttttgatca agaaatttgc taagaaatac gtaacaacac caaaagcgat
    10681 cacacacaac acgaagttga taagatctcc acctagaccc gctttgatag ctaacggtgt
    10741 ccgagtcagc aattcgatat tcccaaatga atggacccgc aatggcaaga tatctgccat
    10801 cgcaaatgca gccccttgga tcactgaata aatgacatat aatggcacag cagcaaacat
    10861 aaacatgaac tccaatggtt ctgttacacc tgttagaaag acagccaacg ctgctgaaaa
    10921 atacattgat ttatatcttg ctttcttatc aggatcgaca ttacgataca tcgcaaaagc
    10981 cattcccatc aagatacctg aagaaccaat catttgtcct actttgaaac gagccggcgt
    11041 ccagttatgc aacacaaact catattgcga catatcccct gcacctttaa gattcactaa
    11101 atcagtggcc caagccaacc ataacggatc ttgcccaaat acttgtgtcc ccgcctgtgc
    11161 gcctgataaa atctcatacg atccgccaag ctgtgtatag ttgataggaa tcgtcagcat
    11221 atgatgcaat ccaaatggca atagtaaacg ttctaatgtt ccaaataaaa acggtgctag
    11281 aatcggtgcg ctttcttgtg attctgcaat ccataaacca aaattattga ttccagcctg
    11341 tacgtttggc cacaccacag caagaatcaa tgccacgatt gttgaccata agataacaac
    11401 aaacggaaca aagcgctttc cattgaaaaa tgacaaagca tccggcaatt ttctataatt
    11461 atagtactta ttataagcca ttgccccgac aaatccagcg atgatcccta cgaatactcc
    11521 catattcaaa gctggtgctt ccaatacact tgtaaaaaat cctttaacca tgatcttcgt
    11581 accgaacaga gtgtgggtaa atgcatcttc attcgcaagc atgtcacttg tgacaccaaa
    11641 gatagcccca gtgatccgat tgattaaaat aaatgagatc ccagctgcaa atgctccgcc
    11701 tgctctttct tttgcccaac ttcctcctat tgctaaagca aataaaatat gaagattacc
    11761 aataattgcc caaccaatat tttcaattac tccgcccgtt gtgacaagcg gcgtccaatc
    11821 aggattgatc aagggaattg atttccctat actgatcatc aacccagctg ccggcataac
    11881 tgctaccaca accattaaag cctttccaaa tttttgccaa aactcaaaac taaatatctt
    11941 tttcattccg tttagctcct ttacgcaatc ggtttcgtta aacgtattat agcgtgcgtt
    12001 ttcttttttg taaatgcttt attttttatt tttctgtcta taccattcta taaaacctat
    12061 aatacgtgtg ttcccttcta taattttctc ctaaaaattt atttttttaa gcttttttct
    12121 atgaaatatt ttcttttgtc tattgacttg tgcaatcggt tgcgtttatt atgaacgtat
    12181 aaaacagctc attaggagga gaaaaatgaa acagatcaaa cgactatttg ctattgatcc
    12241 atggaaaatc agcacgacac aattagataa aaaaaatctt cgactgcaag aatctttaac
    12301 aagtattgga aacggttata tggggatgcg cgggaacttt gaagaaactt actcagggga
    12361 ccaccatcaa ggtacttatt tggcgggtgt ctggtatccc gataagacac gtgtcggctg
    12421 gtggaaaaat ggttatccag aatactttgg aaaagtgatc aacgccttga actttatcgc
    12481 gatagatatt tcgatcaacg atcagctgat cgacttggct tctttggaac cagaagactt
    12541 ttactgggaa ttagatatga aaaatggtgt attatctcgt acattcacaa tcactacttc
    12601 tactaataaa gtacgcattt ccttcgaacg ttttctgagc attgtcaaaa aagaatcagc
    12661 ttatatctat ttaactatag aaatgcttga aggtagcgga acagtcaaac tcgtatcaaa
    12721 attggatgga aatgttcaaa acgaagacag caactatgat gaacattttt ggaatgagat
    12781 tgatcgtgga actatagaag aaatcggcta tttgacgact aaaactattc caaacaactt
    12841 tgggattgaa caatttactg ttactgcagc aatgcgccat ttcgttaatg gaaaatcagt
    12901 catccctgac tatcacgaag atactttagc attacatggt tgcttgtctg cagaattatc
    12961 tcaaggtgag acatggtcag tggaaaaaga aattatcgtt cttactagta gagatattcc
    13021 agaagcgcag caagcagaaa aagctgtctc agaattaacg aaccagacaa acaattatat
    13081 ccaagcaaaa gaagagcaaa cagcggcttg ggcagaacga tggaagcttg ccgatgtggt
    13141 catcgaagga gacgaagaag cacaacaagg tattcgattc aatttgttcc aactattctc
    13201 tacttactac ggcgaagatg aacgattgaa tatcggcccc aaaggattca caggagaaaa
    13261 atacggcgga gccacttact gggatacaga agcgtatgct gtccctcttt atcttgcttt
    13321 agccaaacct gaagtaacta agaatctgct gaaatatcgg cataatcaac tgccgcaagc
    13381 aatccacaac gctcagcaac aaggattaaa aggcgcgctt tatcctatgg tcaccttcac
    13441 tggtgtcgaa tgccataacg agtgggaaat cacattcgag gagattcacc gaaatggcgc
    13501 gattgcctat gcaatctaca attatacgaa ttacaccggc gatacggaat atttgaaaaa
    13561 tgaaggactg gaagttttag cagaaatcgc acgcttctgg gcagaccgtg tccatttttc
    13621 aaaacgagca aataaataca tgatccacgg tgtgaccggc ccaaacgaat atgagaacaa
    13681 tatcaataac aattggtata caaatacgat cgcagcttgg gtcttgcgtt acacgcgaga
    13741 aaattattta acttatcaaa aagaagctgc tatcactatc agcgaagaag aactagccaa
    13801 atggaaagat atcgcagaga acatgtactt cccagttgac gaagaattag gaatctttgt
    13861 ccagcatgac acattcttag ataaagatct catgcctgta tccgatattc ccacaagcga
    13921 tcttcctctg aatcagcatt ggtcttggga caaaatcctt agatcttgct tcatcaagca
    13981 ggcagatgta ctacagggga tttatttctt caatgatact tttacaaaag aagaaaagca
    14041 aaaaaacttt gatttctatg aaccaatgac tgtccatgag tcttcccttt cgccaagtat
    14101 ccattcgatt ttagcagcag aattaggaat ggaaagcaaa gctgtagaaa tgtaccagcg
    14161 aacagctcgc ttggatttgg ataattacaa taacgacaca gaagacggct tgcacatcac
    14221 ttccatgact ggtagctggt tgtcgattgt ccaaggattt gctcaaatga aaactgccca
    14281 tgatcagttg agattcgcac catttctgcc aaaaacttgg aaagcttatt ctttccatat
    14341 caattatcgc ggacgtttat tgttcatctc agtcacagat gaacaagtta ctttcgagtt
    14401 attagaaggt tctcctctag aaatttacgt ctatgaacag tcttattctt tagcggatcg
    14461 tctagaaata acgctaagaa aggaggaagc aaatgtttaa aggggtattg tttgatttag
    14521 acggtgtcat taccgatact gctgaattcc attatcgtgc ttggcgaaag cttggtcagg
    14581 aaatcggcat tacgatcgac cacacattca acgaacagct aaaaggcgtc agccgagaag
    14641 actcactctc tttgctttta gcttatggcg gaaaagaaca ctctttttca aaggaagaat
    14701 ttgcagaatt agcgaaaaga aaaaacgatt attatttaga gatgatccag acgatcgaac
    14761 caaaagatgt cttccccggg gtcgtgcctt tactggattc tttaaaagaa gaaaaaatca
    14821 agattgctct tgcttctgca agtaaaaacg ggccattcct acttgaaaaa atgggtctta
    14881 caccttactt tgatgctatt gccgacccgg cagaagcaac aaacggaaaa cctgcgccag
    14941 atatcttcct ccttgcagca aaagctgtcg gactaaaagc agaagaatgt atcgggatcg
    15001 aagacgcgca agccggtatc caagccatcc tctcaagtgg cgctcaacca attggcgtgg
    15061 gacgtgctga agaccttgga gaggagatcc cgcttgtccc tgatacgact tttcttacga
    15121 tcgattactt gaaagaaaag tggcatgacc atggataatc cagagatctc cgtcgtacca
    15181 gttccagaga ctgaaataaa gaaaatcaca ttgaagaacg actacttaga agtcgttctt
    15241 ctcaattacg gtgcccgcct gcaccaaatc ttcgcaccag acaaagaagg aaaatcagaa
    15301 aatgttttat tgtcttacga tcgtttcgaa gatgttctaa cagacaaaag cttttttgga
    15361 gcaactgtcg gacctgtagc cggaaggatc cgggatgctt cttggggtga gcatagattg
    15421 gagaaaaact gcggatcaca ccatatccac ggtggcacga aaggctggtc tttccaattt
    15481 tgggaagtag aagttttcaa aactccatca tcaataggtg tggtctttta cttaaaagat
    15541 gaattttcta cctatccagg accaatcact gctacgatca cttaccgttt aacaaaaaac
    15601 gaattagaga tgacaacctc tgctagtagc cttgttgaaa ccatctgcaa tccgaccaac
    15661 catgcctact tcaacctttc aggaaatgga acaagagaca tctatgaaca tcagttaacg
    15721 gtctttttag atggtgtgct tgaattagat caagaaaaac tgcctactgg aaattggaca
    15781 aaaaaagaaa aactgccaat cgactttaga aaatccccaa cactgcaaga gatccttgca
    15841 tgttatccag atggactaga tgatgtattt cttttgcatc atcctaggct ttccaaaact
    15901 tccttacaat tattcgagaa gcattctggt cgccaaatga ctatagcaac ttctaataaa
    15961 agtatggtat tattttctac gactggattc gaagctgatt tctctgtcaa tggaaaacag
    16021 atgcattcaa actacggatt agcaatcgaa ccgcaagaaa tccctgatat cgttcatttc
    16081 cccaaatttg gatcgatcaa cctccatcct ggtcaagaac ggatcagtca gacgatttat
    16141 cggttctctg cacaataaca agagaaaggt gtttttatca tggctattac cgtaaaagat
    16201 gtggcgaaaa aagccggtgt tgccacctcg accgtctctc gtgtcatcaa cgatcatcct
    16261 agtatttccg agacaacaaa gaagaaagtc cgaaaaatta tggatgaact aggttatgtt
    16321 cctaacatga ctgcccgcaa tctaggaaaa cgcatttcca gtgccatcgg cgtaatctta
    16381 ccccctcttg attcaaaaga gcggatcggt aacccatttt atcttgagat catggaagca
    16441 atcaacgaag aagcgcggaa ttatgatatg actacagcaa tcgctactgc taaaaatttt
    16501 gaattgctgt tagagaacgt ccagcgtatg catttacaaa aacaagtaga tggttttatt
    16561 ctagtgtatt cagatagtca agatactgtc attgattatt tataccaaaa ccacatccct
    16621 ttcactttga tcggacagcc ttatcatcat gagaacgaaa tcgtttatgt agataatgat
    16681 aaccagcttc taggtaaaca agcaacagaa tttttgatcc agaatggaca taagaatatc
    16741 ctgtttgtga caaacacgac tcatgaaagt ttgtatttcg aacgatattt cggttatcaa
    16801 aaagcaatga tgatggctgg tcttcctgcg ttatccagtg tagtactaga gcatccggag
    16861 gattatctgt cctttgagaa aacgttgaaa gaaaacgaag ccacagcatt ggtggtcatt
    16921 gacgatatct tcgcccttcg cacgatgcag ttggcgcaaa tgtatggcta tgtcattcca
    16981 gagacactct ccgtcattag cttcaacaac tcgatcttct caacattaac acacccttac
    17041 cttacaagta tcgatatcga tatctccgaa ttaggacgtg tcgctatgca aaagctgcgc
    17101 gaattgatcc atgaagaatt gagcagtggc gtacgtttgg tcatccctca tcgcttgatc
    17161 aaaagagaga cagtcgttcc tttagaaaac ccatactaaa tagctgactc actaaatacg
    17221 ctgaccattt atcctatggt cagcttttta tgtaaaagaa gatactactt ctaacacatt
    17281 gtttatctgt aaaaaagagc gtgggacaaa agtaaagaac acttttgtct cacgctctaa
    17341 acacgtataa acggcggaag cagaagcaac tccttcggaa ataagctgaa attcacaaaa
    17401 atttaaaaag caattttctt gagtttcttc ttatttcttg gagttaaacg cttctgtccc
    17461 agcctctttt ttccttcctt caatttttta cacgtcgacg attcaataaa aaaccgccta
    17521 atattgtaaa gacaggtgca agaatcgaga aaaaggcgaa tggcaagtaa tgcaacgcgc
    17581 taactttcat cgttcccata atgaatgtgc cgctgactcc ccacggtacg agagaattga
    17641 cggtcgcacc tgaatccgct agtgttcgtg tcaaataggt ttttgataag ccaacgtcat
    17701 caaaagaacg cttgaatgtt tctcctggaa gaatgatgga cagatactgt tctccaacga
    17761 tcagattgat tccgatacag ctcaaggcag taaacccgac taaacgagaa ggtcggtcca
    17821 tcttttcttt taattcttga acgatggtat caacgatcag atatttgatc agtaacccac
    17881 ctaatgccaa tgcaagtaaa atcaaactag cagaacctaa catactcatg atcccgcctc
    17941 gagaaagcag ttcatctagc tttggatcag gtgtatttgc gacataacca ttcatcaaga
    18001 tgtctgctgc ttttccgacc gtcaaacttt tctcatggat aaaagaaaga acgagagcag
    18061 ctgtcgatcc cgctagtaat gtagggatag ccggaatttt tttgattgcc cccccaaata
    18121 aaataactag tggaatcaat gtccaaggag agatccaaaa gctcgctttc atgttttgga
    18181 tcatttcatt gatactagct agatcggctg aatgactgtt atgtcctaat atcgtataaa
    18241 aaatcaacga aaggacgaat gctgggaaat ccgtataacg cataccagcg atatgttcga
    18301 atagattaac tcctccaata cccgctgcca agttggtcgt atctgataaa ggcgagcagt
    18361 tattccctaa aaaggcaccg gaaacgactg cgcctgtagt cattgcatca ttgaatccaa
    18421 gtaaatgacc gatccccaaa aaagcaattc caatcgtcga aatcgttgta aatgaactgc
    18481 cgacagtcac tccgacaatt gcacaaacaa gaaatgctgt cggtaaaaag aaacgcacag
    18541 aaacaagttt aaatccataa accataatcg tagggatggt tccagataaa atccatgaag
    18601 caactaagac accaatcaaa agaaaaatca ggattggaat gatccctgga gtgattcctt
    18661 tgatgatccc gtcatggatc tcatcccatg tgaacttttt aaatctgcca taaaacaaca
    18721 aacacatgaa agctgcaagg atcgggatat gtggcgagag ctggaatccg atgatcagta
    18781 ctcctaggag tgccaacaac acgatcaata cagcgatact ttcttttaaa gaaatatttt
    18841 tattcatcgt cgatctccta tttcaaatga aaaggccctg ccatgaaaaa actattcact
    18901 tggcaggacc tcctactaaa tcagcgacaa aacgtcggct gaaagactta tttttttatt
    18961 tttcttctaa acttttttct acctcaatcc cccaagaatc tttcttgaag tgattgatga
    19021 tcaatggaat aacgaacatg accactgtga tagctgctac taataatgca tcactcaatg
    19081 tcgctgtacc taatgtagca aatacgacaa cgatgataga gaagatcagc atgcagctga
    19141 ctacccaagc taatccgttt ccgtttttac caattcggta aggacgttcg aattctggat
    19201 gtttcttacg cattttaagc aatgaaacag caatcaaaat gtacacgata caataaataa
    19261 cagttgtagc atttgtaagt gtcaagaata cagcacttac gtcatccatt acaccataaa
    19321 gcaaagcaaa taatgaaata acgattgatt gtgttagaac gacatttcta gatacgccgt
    19381 atttgttttc tttatggaat ccgaattttg gtggaaggaa tccttcacga gctacttgga
    19441 tgattgtttt tgatggtcca gtaacccaag ctgataattg taaaagcaca ccaataaata
    19501 ccatgaagct gaagatattt ccgatcactt ctggtaagcc taggatttga cagtcaatca
    19561 agataggctg cgtgatattt gctaattcca tttttccatc tggtacgaca tttgctacaa
    19621 gcatcgcatt gatgacattc aataaaacta atccgatcaa agcgataaat acgccttttg
    19681 tataattttt tgttgcgtct ttcaaacgag gcatgtaaac agaactcatt tcgatcccaa
    19741 caaaaataaa tgtgatacca gctaagtatt tcaatgaatc aatatgttcc aagtcaggga
    19801 aagcttttga ccatgaaaag tcacctagat agccgtttga gactagtccg actttgaagg
    19861 ctgccaaaac acctaaaacg aacatgatga ctactgggat atatacccct agccatacac
    19921 cgatgttccc gccgactttt gccatatcga atttcaagtt caagatcgtg atgatccagt
    19981 agataactaa aatacaacct aaaacgaacc agtgattatt gccaagttct acattaccaa
    20041 atgtgtttcc taacaatggt cctaaagtag aagcgaccat taccatacct gggaacattt
    20101 gcacccataa tagccatgca acgacaaatc cccatttgct gcccagtgct gtttttaccc
    20161 ataactgagg accgccttct tgaggaagca tcgtggaaag ctcaccggaa accattgata
    20221 tcggaccggc aaaaaacaaa actgcaaaaa ttgaataaaa aatcaatgtc caaccgactg
    20281 cggctaacgt aggaatactc cgaaccgttg cacacagtgc cattgtcaga ccgataaagg
    20341 tcccaagacc cattttactt acttcagatt tactcaccgt tgacactctc cttgattttt
    20401 tggataaaat aacggtgtct ttgaagtagt ttcagcaata aacgaaacaa ttcagcgaat
    20461 atttgagggg attctttgag tttattgctt gaagggtttc ttcaaagaca acctcaaaac
    20521 aaagggatcg aagagcttag gtctcccctt gctcttcaga tccaaacatg cgtcagaaac
    20581 agttagtatt caagctgttt tctaacatga ttaccttgct tattttgctt cgcttgccaa
    20641 taattggtct gcgtagattt tttccaattt ttcttgaaga gctgctttga ttttttcagc
    20701 atattcttca aagtgttctt ctttgttcat gtatggtgtc attacgctgg cacgcaatac
    20761 agttactttt ccggcacggt tccattcttc atctgagaat cctagttggt tcacaaattg
    20821 taatgggctg ttgccatagt ctgggatagc aaagtcagta tgtgaagtta agaactcatt
    20881 accgtaaatg cttcctttca cgtatgaaga ataatcatat acgtcatggt tcaatttatt
    20941 cattgcaact aagtcatcgt tgcctttttc tttgaataca tagtctacca tattgaaatc
    21001 tggataagtt aatggatgaa cttcgatttc tttgtctcct actttaaatg acaagtcatt
    21061 caagaagttg tagaaacgat gtgcaccttc gattgatgca cccattaatt taccatatcc
    21121 tgtgacattc aaaggtaaga catggtgtgc tgcccaaacg ctggctgctg ttgcccctgc
    21181 ttttgaacct tccaagatat aagccccaag taatgctggg atatctgcgc ctttttcaaa
    21241 tacatatgtc gcaaagtaag agataacgtc tctcatgcgg atatctttga tgacgatacc
    21301 accggcagaa tatggaacat agcccatttt atgtgggtca atcgttacag attctgcttc
    21361 ttcgattgct ttatatgcac tgtgtacttc ttctaagata taatctttgt tttctgtaaa
    21421 gacattgtat ttgtaatgaa catcttttaa atcttcaaat ggaatgaagt tgttgtcttc
    21481 gtctaagaaa atcgcacggc cgtatccgcc ataagcagca tctacgtgta agtagaagta
    21541 aataccgtct ttttctaata cgcgacgcaa tgcaacgatt ttatcgatac cgtcgattgc
    21601 tccttcttct gttgatccta caacaccgac tacacctagg attggtgttt tttcagctgc
    21661 tagaccacga acgatttttt caagttcgtt gatgtccatg cgatagttgt ggtcaactgg
    21721 cactggaatc acttggtcta aaccgatacc gatgatgtcg gcagctttta gccatgaata
    21781 gtgtttagtt tgtggaacca accattttcc taatttttct aaatgttttc cgctacgtgc
    21841 tgagtgagct ttgatttcgt cgattttttc tgggacgctg tctaacagat tcatgatttc
    21901 ttctgttgac aagttcatta attcccaatc gctttttcca gcaactagtt caggtgtcac
    21961 ttctttcatt gcaagcggca atgatttgat gttgcgggca taccaaagtc cttctaagtt
    22021 tgctaaagaa ccatcagcaa cgatgtggcc ccagccatct ttatagctca ttaattttgc
    22081 aaattccatt cctacttctt cttccatttg gcttgttgca ggagaagatt cataggcaac
    22141 gttattacca ttccatagca tagcaaaatt gtacgctagt aaagatggca tcaatgtttc
    22201 agagttcata tgaccccagt aacgtccggc attatgccaa ggaacggaat gggtacgcat
    22261 ccgcgctgaa atttctgata gaacatcctt tgttttattc acagtgtgtt caaaactagc
    22321 actgcttttt tcttctggcg taataatagg catgtcttga ggcatgtagt tttgacgcca
    22381 gcctaaatgt tcatccacca attcattcaa caaagcttta tagatttggc cgttctcagc
    22441 tttgtcccca atgaataggg catttaggtt tagatctttc gacaatgatt cactcatagt
    22501 gaaaccctcc taaaaaaata tttaaatttt gtcgagccct acattacacc tgttcttcta
    22561 ttctgtaaac taagttttgg cctgattttt aatcatattt taatatgtat caattatccg
    22621 aattgttcac acttttgaaa taattaaaaa aaacgaggga atttacaaat gtaaactccc
    22681 tcgcaaagat tgtattaacg acaaccagcg ttctatttta ggatgggttt caaaattgga
    22741 atgttgtaat agtatttccc tttttcaagg taaaaactta ctaaattcta atcaattact
    22801 ttggccaaaa agtaattttt cttacctttt cgaataacca caaacttacc atcgaattca
    22861 tcggatggat ttatgacaaa atttaaatcg gtaacgcggt caccgttaat acttatagct
    22921 ccgtttgaaa catcttcacg tgcttgacgt ttagatggtt caatttttgt ggaaacaagc
    22981 agttccacga tattttcagg tgtgcttgaa atttcaacgt tcggcatttt accgaatcct
    23041 tgcgcgattt cttccgcatt tagttcttta atatttccag agaacaatgc ttgcgttatt
    23101 ttttgcgctt ctttcaagtc ttcttcacta tgcacaaatc ttgtaacttc ttctgccaaa
    23161 cggcgttgtg cttcacgttt ctcaggttct gtctctactt ttttcgctaa gtcttcgatt
    23221 tcttcttgag acaagaaagt aaagaatttc aagtatttca ctacatcgcg atcatcttga
    23281 ttcaaccaga attggtagaa ctcaaatggt gaagttttct tcggatcaag ccaaacggca
    23341 ccgcctgcag tttttccgaa tttcgttccg tcagccttca gcatcaatgg gatcgttaaa
    23401 ccgaacgctt ctgcttctgg tccttctaat tttcggatta ggtctaatcc agctgtgata
    23461 tttccccatt ggtctgctcc accgatttgc aattgcacat cgtatgtttt atgcagatgc
    23521 aaaaagtcga tagattgcag gatttggtaa gtaaactctg taaatgagat tcctacttcc
    23581 aaacggctgg caacgatatc ttttgctaac atcgtgttga tgttgaagtt tttaccgtag
    23641 tctctcaaaa attcaagtaa agagattttt gacaaccagt cgtagttgtt cacaaatgtg
    23701 atatttgcat ctttaccaaa caattttctc atttgattgg aaagtgcgtc cacgttatgt
    23761 tgcacttgtt ccatcgtttg caacacacgt tctgttttgc ggccgcttgg gtcgccgatc
    23821 gttcctgttc cgccgccaat cagaatatat ggatgatggc ctgccaattg gaatcttttc
    23881 atcatcataa atggaatcaa atgtccgata tgcatcgaat caccagttgg atcaacgccg
    23941 caataaagtg aaatgctctt ttcttcaacg agctcgcgaa gtctttcttc gtttgtttgc
    24001 tgattaatgg cgtcgcgcca agttaattca tcaataatat tcattttact gacctccgtg
    24061 tagttttttt atgaaagcag gaacctgcta gcatatgtaa ttaattattt cttcaggata
    24121 ggataggaaa taaaaaaagt cccttggcat ataagccaag ggacgaaatc tcgcggtacc
    24181 acccaatttg tatgtctaga tatccaacat acctctcgaa catttaacgc tgtcgcgtgg
    24241 caatcactgc caaagactcc tgaaatgtaa ttcgctttaa agcatgtact ggtttgcagc
    24301 gaccaccagc tttctgaaac attggcttta acaactactt cgtttcgatc ttcgtcttgt
    24361 tattattaat atgtgtctat catagagcgc aactttttct ttgtcaacag aaaaaggata
    24421 ttttttttaa attcctcatt ttttcttttt tgaatccgct ctaattccga acattttatt
    24481 ttcaattatt gttaaaagaa ataacttttt ctgtattttt tctgcaattt atcgagaagt
    24541 cactttactt tgcctcttat tctttcttcg ttacaataag gaatgggaca agtaaaaaaa
    24601 tgaaaaagca agggacgagg tatatggaaa aaaagcaaaa aattatttta ggagccactt
    24661 ctgctttaac tatcgttatt ttaattctaa gtttgttttt tgtcatccga tcatctacaa
    24721 aaaaagaacc aatcattcct gaaaaaaaaa taacagaaaa agcaaaagaa ccgacagatg
    24781 ataagcaaca actagttact caagcaaaaa atctggctca aagctacgat tatgaccaag
    24841 cgattgcgtt attggaaaaa gatagtaaga acggatctac tgaaacacaa cagcttcttc
    24901 aaacactaaa aaaggagaaa gaacaactga tcgactggtc tgatcctact cagatctctc
    24961 atgtcttttt ccacagcttg atcgtggacc cgcaaaaagc cttccactct caacaggcac
    25021 aaggatacaa agattatatg gtgactgttg aagaattcaa ccgttcgatc gaacaacttt
    25081 atcaaaatga ttttgtttta gttaatttga atgatttgat ccaaaaagac gaacaaggaa
    25141 atctttcctt taacgggctt gcgctacctg aaggaaaaaa accattggtt ctttcacaag
    25201 atgatgtcag ctattatgaa tatatggata attccggttt tcctagccga ttggtcgtat
    25261 caaataacaa tgaaatcaaa aatgtctata aagagaaaga taaagaagaa atcggtgact
    25321 ttgacatggt tcctctgatc gatgcctttg tcaagaaaca tcctgatttt tcttatcgag
    25381 gcgcaaaagg taccttggcc ctgacaggtt acaacggagt tttaggttat cgaacatcaa
    25441 aatctcaata tggagacaat gaaaaaacaa aaaaagagat taaagaagct aaaaaagtgg
    25501 cggaacagtt gaagaaagac ggctggagct ttgcttccca tacatggggt cacttgaata
    25561 tgactcaagc ttcactagaa gatgtaaaaa aagacaatga attgtggcag caagaagttg
    25621 cacctatcct aggaaaaaca aatattctga tttatccatt tggtgcagac atcagcgact
    25681 ggcagcctta ttcagcagaa aatcaaaaat ttgcttactt gaagagtcaa ggtttcgata
    25741 ttttctgtaa tgtcgatgct tctacaccag cttggggaca attaggtacg gatttctatc
    25801 gaaatgctcg gatcaatatc gatggcattc gttttcaatc tgatttagac ggaaaaaatc
    25861 ctattcttga tccattcatc aatgtccatg atgtctatga caaagaagca cgcgaatctg
    25921 cttgatttta cgtcatttat gaaccaaaaa agccgaactg acattttatc gtcagtttcg
    25981 gcttttttat gctttatttc ttcttcggtg cgattccctt gatcaggact tctgtccatt
    26041 ctgctgtata tggaagcagt tttgcgtata tctccggctt agaaattcct tctaccattg
    26101 cttgaaaata gaggatcaag aactcatccg aatatttcaa atccactttt ccttctttcc
    26161 gccctcgatg gaaaagatca agcatgatac tgaaactttc ttgcgtatac gcatccatcg
    26221 cgtcagaaaa ttcttttttt tctttttttg tatagtatgt catcaaatcg atataaaatt
    26281 gtttgttcac tcgattgaga taacggattt tgttttcact catggcaatc agtgtttctt
    26341 caaatggaag attttccgca atcaacgctt tcgcttcttg ccctaaatca ttcataaatg
    26401 caaaaaatac ttcataaatc agcccttcct tgctgccaaa atatttaaaa atcgtcgctt
    26461 tacttacctg agcgttctca gctaccttat ccattgtcac tccagcggtt cctatgtctg
    26521 tgttcatcaa gtcaaaagct gcttgtaaaa tctctttctt tttctcttgt gctctctttt
    26581 caaaaccgtt catttgtaga gcctcccgta attttaaact tttataatat atatagttca
    26641 aatttattct gaggtttatt ataactatct attgagaaag tatcaagcta gcaattcctt
    26701 gtttatgaat tcattgacag aaatttataa aaagaatatt atgtactaaa ataataaaaa
    26761 aagttttata aaaaggtata aaaccttttt attaaactat ttaatcttgt ttagtatata
    26821 tttttagaaa aaggagtggg gtttttatgg cagaaatcgt caaagtcaca catttgaaaa
    26881 agagctttgg tcgtttcgaa gctttaaaag atgtctcttt caccgtacat tcaggtgaag
    26941 tcgttggatt tatcggacca aatggttctg gaaaatccac gacgattcgg acacttttag
    27001 ggattataaa aaaagacggc ggaacggcaa cgatttttgg gcaagatgta tgggaagata
    27061 gtttatctat ccatgaacgt ctttcttatg ttccaggcga tatctctttg tggggaaatt
    27121 tgactggagg agcgatcatc gatctcttca tgaagcttca tggaaaaggg agtgctcaaa
    27181 aaaaagatga actgattcaa cgtttctctc ttgatcctaa gaaaaaagca aaaaactatt
    27241 caaaaggaaa tcgccaaaaa gtgggcttga ttgctgcttt ggctgttgat tcggatctct
    27301 atttatttga tgagcctact tctggtttag atcctttgat ggaaacgatt ttccaagaag
    27361 aagttgaaaa attgaaagaa cagggcaaat ccatcctact ttcttctcat attctcagtg
    27421 aagtcgagcg actagcggat aaagtcgtga tcatacgcga aggaacactc gatgaagaag
    27481 gaacactcga tgaattgcgt catttgactc gttcgaccat cactatagaa acagaagcag
    27541 agaatagtca cttagcacaa ttgaacggtg tccatgactt tgtgcaaaaa ggtcacctcg
    27601 ctcaatttgc tgctgataac gaagctttcg atgtgatttt agctgaagcg tccaaattag
    27661 gtgtgaaaaa atttgaatct attccaccga ctcttgagga tttattcatg agacattatg
    27721 aaggatgagg aggaagcgaa atgactgata aattttcacg ctggtccacc cttttttctc
    27781 aaaaccttag ccgtgactgg aaaaagatcc tgatatggct agtcggtgtc actgcttttt
    27841 ctggtggttt tgtccctgcg tttgaagaat tgacttccgg acaaggatta gctggattat
    27901 acgaaacctt gcaaaacccg gcaatgattg caatggtcgg accaactcca gcttcgaatg
    27961 ctgctgagta tactttagga gcgatgtatg caaatgaaat gttgcttttt tgcagtttgt
    28021 ttgctgctgt gatctctgtt ttacacgtgg tgagccaaac gagaaaaaaa gaagaacttg
    28081 gtctgattga acttattcgt tcctttcgag tcggacgtca agcaaactct ttagctgtca
    28141 tcgctgaaag tattctgatc aatttgcttt tagcaatatc gatcagctgt acgatgattt
    28201 ttttccaagc ggattcgatc actgcagaag gtgcttggct ttttgggcta tctgtaggta
    28261 gtatggggat tttggggagt gccgttgcac tgtttgctgc acaactgatg ccaagttcag
    28321 ccagttcgaa tggtctgtct ttagcgtttt taggtggact ttaccttcta cgagcaataa
    28381 cagatgtagc tgattcctcc ctttcgatgt ggaatccttt aggctggtct tatttgacct
    28441 atccatttac aactaacaac tggattcctt tgctttattt gtttttgttc agtctaatct
    28501 tgataatcag ttcatttgtt ttagaggaac atcgagattt gaacaccggc tatatccccg
    28561 aacgtgaagg aaaaccgtat gctaaacgtt ctcttttatc cttgcgtggt ttattattct
    28621 atctaaataa agggatgaca atcagttggc ttatcacttt tggtttgatg ggggcggcat
    28681 acggctctat ctacgggaat atgcaacagt ttttagaaag taacgactta atgaaacaga
    28741 tgtttatcca atctggcgtc tcaattgaaa aaaactttac aagcacgatc atggtagtct
    28801 tgatttgtct agctgctatt ttaccaattg ctagcatcaa tcgtttattt acagaagaaa
    28861 cccacggacg tatgaatcag ctgttcgcaa caaaaatttc taggaaccaa ctttattgga
    28921 ccaatatgtt actagctatt ctatttgcta tattggcaat cctgattagt tctggtgcac
    28981 tagggctttc tgctttggct tcgatgaagg atgcgaaaga catggatcta ttgatgtttc
    29041 ttaaagccgg gttcaatttc ctgcctgccg ttttagtgtt tatcggaatt agtggctttc
    29101 tattcggatg gcttcctcga atcggtaaac ttgcttatat ctacttagct tactcctttg
    29161 cactcaatta ctttggcgga attttggatt taccagaatg gttttccaaa acagctgtcc
    29221 ctagctgggt tccacggatg ccaaacgatt cttttgatct ttccgtgttc cttacgttat
    29281 catgtatcag ccttgcactg ttcgtccttg gttctattgg ttataggcga agagacttac
    29341 tagaaggata ataaaaaagc atgtacaatt tcatgctagc ctccaaatct gggtcaaaaa
    29401 tccaacattt ggaggtcatt tttttattta caagtcttct aactgctctt tatcaatgat
    29461 ccagacttct cgattctttc tttttacata accattctcc tctaataatt taaattttct
    29521 agataaagtt tcgggggtcg taccgataaa tgcagcaagt tctttcattt tcattggcag
    29581 gaaaaagtga tccttccctg tcgctttagc taagtcaagc agatagacag cgactcgttc
    29641 ttctactttt tccatcatca aaaaagttgt ctgctgctgt acttttgtta atttctcaac
    29701 gttgattgct aaaagtttca gactaagggc gggataatgc agtaagagtt ccgagaaatc
    29761 tttttgtctc aatatgcaaa tttccgtttt ttctagtgct tcgccaaata aagactcatt
    29821 tggaacgcct agcaactggc tctctccctc atatccgccc ggctctatta ctcgtaaaag
    29881 ctgttccttt ccgctagcag ataattgata cactttcata ctgccggagg ccacgatcac
    29941 taattgaggt tctccattcg gcgcaagaat ctgttctcct ttttccacat agtgatgttt
    30001 gacaagtgcg tgtacttttt cttgatcttg ctgtactaag tgattgaaca aaggaacaaa
    30061 tgaaacacat aaatgatcat gactcataat ctctcctcct tctaaacagc tatttctaat
    30121 aaagaaacat aacttccctt attccaactg ataattttct tttatcatag cataaacgtc
    30181 aagcgaacca gataccagca aatagagtgg atttcttttt gtcccttgct ttattttcct
    30241 tcttttgaga ccttaagtaa ttgattccta tcaatttttt aaatatttac tttttgaata
    30301 atcaaaaaca aaccttcact cgcaagccga gagtaaggtt tgtttttcgc attgcttatt
    30361 tcgtgttgtc tattgaaatt tttccgcacc tagcttttga tatagtggtg ctagttcttg
    30421 taaggtttca gcggttattt gctcaacgtg ttcgatttct tgcggataga agaatagttt
    30481 acccatttga aaggttcggt ctctcatcgc ttttttcaac tcttcttgtt tctttgtatc
    30541 ggacaaatag tcagacaaag ctaagtggtc gtcaagttca tgttctggtt gcggccatat
    30601 gtaataatcc ttgatatcga ctgttttgct ccactctttc agtatcgcaa gcaactggtt
    30661 atacgctgca atgctaccat atcgttcttc gcttttataa tgttggtaca tcaaatagat
    30721 ttggtattgt ttttgattca acaaaactgc tagacaggca ttctcgtctt gacgagattc
    30781 gcttcggtac gcgctccaaa aatgactgcg taaattccag ccattcgtcc agctttcgat
    30841 tttaggtttg ctcatgccgt acatatcagg caaaagtgca gctgtctgga gctgaatctc
    30901 tttccatttt tgccagtgtt ctttatattc tttcttgatt tgttcaatct tatctgttgg
    30961 atggctctct ttgagctgtt tgaatgcgta gattggtcga tcaaacaact gataatctga
    31021 ttttccaagt tccattgttt cgcctctttc cgttatcttt tgtattctac ctgaattttg
    31081 cgatatggac aaatagaggt tgtgaaaaag ctgttctgca tcaagtcata agaacagcca
    31141 aacaaaaaac tgcgatgagc atcaccgcag ttttattgaa cttaaggttg attgatcaca
    31201 tctaaaagcg ttgaaaataa aatggcacta gaagcagctc ctgggtcgat atgtccgatt
    31261 gcacgctctc ctagatagga agctcgtcct tttttagcta ccaagacttt ggtgtgttct
    31321 tttgcctggt caatgatttc ttttgttaaa ttccctgcct tcaatgcctc tgtgactggc
    31381 agccaaacat ctaacatcgt tttatcgtca gcttctgcct ttcctcggct ttgaataccc
    31441 gctgttccct gctcgatcac ttcgcctaat ttttcttgag aatcaataga atcgacctct
    31501 tttgtcgctt tcatcatgtt catgaatgca gatccgtata acggaccaga agccccaccg
    31561 actttcgata tcatcgccat agagaatact ttgaatgtat cgctgattgt ttcaggatga
    31621 tcggcttgaa aagcttcttc ataagctgaa acccctcttc ccatgttatt tccatggtct
    31681 ccatcgccaa tcggggtatc tagatcactg agatattgtt tgttctgatt gattgcctct
    31741 gcaaattgcg tgagccattc ttggatttct tgaacggtta gtttcatatt atcacccttt
    31801 tatcttgaga ttttttacca tgaaatcgtc tgtacattgc tttctaaaga atctttccat
    31861 tgtgtctccg tcaagtcgat cagtgttaga gaaagacctt gcatatctag tgaggtcata
    31921 aaattaccga cttttcggaa aactacattg acgcctcttt cttccaacag agctaaaaca
    31981 tcattcatga acacgaactg ttccatcaaa ggcgtcccgc ccattccgtt gactagtaca
    32041 cctgcttctt ttggtaaatt cgagtaatca tctaaaatct tagtaacaag ttcctttgcc
    32101 agtactttag aaggctgcat cttttctcga cgatagcctg gctcaccgtg gataccaaca
    32161 ccatactcga tctcatcttc tcctagttcg aatcctggtt tccctacttc tggtacagtt
    32221 gctgctcgaa gcgctagacc gatcgtctta gttgcctgta cgaccttttc tcccagttct
    32281 ttcaactcag ctagggaagc accgtttctt gctgcatcgc ccacgatttt gtgtacaagg
    32341 acagtacctg caactccgcg ttttccagca gtatacgtac tattttcaac ggcgatatca
    32401 tcatctacga tcacactttc tacttcaata tcgtccatag cagctaattc ctttgccata
    32461 tcgaagttca atgcatcccc tgtataattc ttaacgatca gcaaaactcc ttttccacta
    32521 tcggcttcct taatagccgt ctgaatctga tctggagttg gagaagtaaa cacatcacca
    32581 agcaccgctg cacttaacat cccttcccct acaaacccgg catgggatgg ttcatgtccg
    32641 cttcctccac cagaaaccaa accaacttgt tccgctttct gattcttggc tacaacacgg
    32701 gaagattcta cacgatgaac aagttctgga tagcttttta ctaatccttc cagcatttct
    32761 tcgacaatat tgcttggatc attcatgatt tttttcaatt tattcccatc ctttctttcc
    32821 ggcattttgt gcttctgtta agatttgctg agtatcatct gttataccgg cagtgatggc
    32881 tgctgcaaaa gctccttcca ctaaaggcgc atccaccaga tgataacgtt gctgctgctc
    32941 ttcttccaac atgtcttttg ccagttccga gttcaatacc gcgctaccga tatccgcaaa
    33001 aacaaaataa ctagctgcat cgcttgattc attgactgct tctacgattt tcatcgggtc
    33061 tgatccgatc tcgccattta ttccgccgag agaaaaaatt tgcacctctt cggatttttg
    33121 catctgctca atcatttctt taataccatc tgttactttt tgactatgag aaataagcaa
    33181 aatacttttt ttcacaagaa tcttcctttc ttttacatag ttgctaacga ttggtttcgc
    33241 tttcattaat gaacaattca agtatataat aaatttctaa ttttgggaaa atatgtgtag
    33301 tgcttcttga agtttgttat actttaatta aaagagagga gtgatcgaat gattacaaca
    33361 acaacgaaca gtgtagaggg aaaagccgta gtagcttata aagggatcgt ttttggtgag
    33421 gtcattactg ggatccatgc atttaaagac ttggaggcgg ggttgcgaaa tatctttggc
    33481 ggccgctcaa aaagctatga aaacgaacta atgggtgcaa gagaagaagc acttgccgaa
    33541 atggccgaac gtgcaaaagc attaggagct gatgcgatca ttggcgtaaa aatggactat
    33601 gaagtattag gcagcgacaa tggcatgctg atggtcacat gtagtggaac agctgtctcc
    33661 acgagataag taggggacat ctgttttaat aactaaagag agatgggaca tgtagtggca
    33721 ctcaagaatt agatttttca gtctaacttc gaggtactct accttcccat cctctctttt
    33781 ttatttcttt ttgcggatga ttccgtaagc tgctgcgact aacacacccg cccctgctaa
    33841 ggaataactg acagaagctg ttttttcatt tgtttttggc aaagtctgac ttgttgattt
    33901 ggatggctct gtcgtttgct gaactgtttc tgtcgtgctt ccagaggtca ctgatttttc
    33961 tcctgccgaa tgcaaaatat cttttattcg ttggaaacta gctgctaagt cagctttttt
    34021 tgcttcaaaa tcattagcaa ctgtttgtgc ttcgctgatc tttccgtgga ttgcttgact
    34081 ggccgctgtg atatccgctt gagtttgact tagctttcca gaagctgttt gagcaacctg
    34141 atttaattgc tgattgaatt cttttgcttg ttggatcttc ccgtcaagat ctgtttggac
    34201 agcttccgct tttgctttcg cttcggcaag ctttttctca agttgtgcac ggtcatttcc
    34261 cactttattt ttaagatcag ctaaatcttg atcgattgct gcttggtctt ctttcaattt
    34321 gttttttgca gcttctaatg cttcttcgag ttcttttctt ttattttcca agtcttgcaa
    34381 atgatcgatt tggtcagaag aggtagaact atttattgat gtatcttctg aagatgaaat
    34441 cgtttctcct gaattatctg tcggtacatt ggaagtcatt tctgtttccg aggcaccgtt
    34501 ttcagcacca gaagagctta tggttgttga aggttctgtt tgagcaggtt cagaagtttc
    34561 cgcaaaagct gtctgtccca ataagaaaat actggaaaca gcaattggcc agattaacgg
    34621 cttcattctt tttttcatca cttttcccat ccttactact ttttaactaa tttcttatta
    34681 taagcaaaaa tgtttggaag aaccataaac acaacaggct gtttgtctaa aaaacggtgc
    34741 atcttttatt tttttgtacg ttccgggctt ttccatgtcc cgcttccata acctaaaatc
    34801 gttttgactg ctggaatgaa agtcgtcacg atcgttatcg cgttcactat ccagaacaaa
    34861 agcatatata gtggtgcgaa aagaaggtat ttcaattttc ttcgtcgatc atctacaatc
    34921 agcgaagcta gcaactggaa aaatcctgcg accatttcaa agcagatgaa cacaaaactg
    34981 aatgtaaaag taatataaat ctgttcgtag tttccttgat atacataatg cccgattaat
    35041 ccagcaaaaa gaactacgga aatacaaaag aatattgacc agacaatact caatgtttga
    35101 tcaatgaaga tgatcgttct tccaatatgt ttaaaaggat ggagcatcac ttttttgaaa
    35161 ttcgtcagcc agacttctgt tccacctttt gcccaacgtt ttctgtgtcg atatagcatc
    35221 ttcaacgtca caggtacttc catgaaaaag ataatctcag gagcaaaaac agataaccag
    35281 tcatttaact gatgatccca agcaatactg atgtcttctg tcgctcgatc ttgtctgaat
    35341 ccgcccacat cgatcaaggc ttcttttcga tacatcgtat ttgctccact gtacgcataa
    35401 agaccaccga aaacagctga ctgtgttcgt ttaatgatgc ccacgatact tgagaattca
    35461 accgtttgag attttgcaat caatttggta cgattttgga catccatatt tgcagtgacc
    35521 gcagcaatat gtcttgcacc agggcgaatg aaataattca catacctaat cagtgcatct
    35581 ggctccggta ccgtgtctgc atcattgctt aaaatcaatt tcccttttgc aaaggcaagt
    35641 ccgatattaa acgcgtgggc ttttccttta tttttttcga tccgaaccac acgaagatta
    35701 gcgtattttt tcatcagtct agctaatatt tctggtgttt ggtccgttga accatcgtct
    35761 gtcactaata cctcatagtt gtgataattc aatttcgtca tcaaatactc gattgtatat
    35821 tcgatcacaa tttcttcatt atgggctggc accatgatcg tgatgaacgg ttcgacactc
    35881 aagggaacat ctacccattc tttttgctta tgtttgtata aaaacacata acaccagaca
    35941 ccaataaacc atacaaatcc gcctaaaatc ggataagaaa cgagaaaaaa atacataata
    36001 gacaaacaag tatctaagaa taaattacct gtatgggtga ttgagatcat ttcagttcca
    36061 ccccattttc tttatacaaa tctgcaatga atgtcgtatc tagatttttc tcttcggaga
    36121 cagaataaaa acggaccgtt tctctctctt cttttgttcc aaaacgttcc gtatacactt
    36181 cttcaagtaa ttcttgtctt tttttcaatt tttcatcttc atattcaaaa gatttattta
    36241 cttttttgta tagatttcga ttgttccacc tagtcaatac aaatgaggta atcaggaaac
    36301 tgaaaaaaat caatacaaaa aagccgatta agaaatacag cattttcttt tctgataaaa
    36361 aagcgtacaa ggaaaaatcc ttggctcttt ctggtctcgt taatgggaaa aagacccata
    36421 taaaaggaag aacaacgatc atccatccta aaagagccac taacgtttgc caaatcttta
    36481 accagtaatt accttttgaa aaatacttat ctttcaccaa aattgatgca acttcttctc
    36541 ttgttacttt tttcatatcc tcacctcacg tttttttgtt acgacgtagg agtttaccat
    36601 acatttcatt tcttttcaca taaagtgttc ctaaattttt cctaagaaaa agaacaaaac
    36661 atttctcatc agcaaatgaa aaatattttg ttctttttat cagttgttct ttttattttt
    36721 tatctcttaa ttatgttgct ctttccaata cgacaatgct tttcattcct ctagatatcg
    36781 ccgtgtacat ttgtctgcgt cttctttgct catctccatc gttttcaaat ggatataaga
    36841 ttacatgatc aaattccagt ccttttgcta gactcaaagg aatgatttgg cagttttcta
    36901 atccatatga atttttttta atcgattctt gtagcgtttg ggtttcctct tctgtttggg
    36961 tgataactgc cgctttttct ccttttagag aaaccaaaat ctcagctagt attttcaaca
    37021 attcttcaga ggatcgaaaa gagcggtatt cgggttcttt tccttgcggt cggatcgata
    37081 cgatgtcgat cttctcttga tccacagcat aggttttgaa aagctctgtg attgctccgc
    37141 tagaacggta actatttcta agatcatacc gatggatcgg cagatggtag tcgtcgaaac
    37201 aacgcataat atcagcaaaa gtagtggaag aattaaagat tgcctgattc tcgtcaccta
    37261 ctaaagtaaa gtgagttttt ggaaataatt cgatcaatag acctaattgt gccagggtat
    37321 aatcttgtac ttcatcaatc aatagatagc gaaatgctgg tacatttacc ttttcaacaa
    37381 gtaaatgacg aatagctaat ataatgactg cttcatcaac agtacgtgtg ggttgccaag
    37441 cataagctga gccatatcgt ttttcataaa ttctttcaaa caactgatgc tcatccaccc
    37501 atgccatttc ttcgatttgt ctggttattt ttcgatattt tttttgtaaa agtttccttg
    37561 cataagctac aatactttgt tccgaatcat cagaaatcaa tttaccgaat aattccaact
    37621 gcctatcttc tgtcaacgag agtacctgat tctgcacagc aggacttttt gcttgtttca
    37681 aaagatgatt cttccattcg ctcatcagtg cctttttcgt tgcttgaagc ctatcgatca
    37741 atttaggatg agcaggaact ttctcatata ttttttcgat cgttttttta gaaaggactg
    37801 tttttccatt tttagtaagt ccacggataa aattcggatg atctaaaaac aaaggatctg
    37861 attgttttag attatcgata aactttttgc tacgcaaacg ttctgtctgc tccgatacat
    37921 tttctcccgt gatacgtttg aaataagcct cttcaccttc tatttcctct gctgaaagct
    37981 gtgaaaccag ctgtatgatg gttagattca gtggatttct ttcacctaat gatggtagga
    38041 cattcgaaat atagtcgata aaccgatgat taggtgatag aatcagcaag tcatcggatg
    38101 tcatcgtatc tcgatataaa tagagcagat acgcaatacg ctgcatgata gcagaggttt
    38161 taccacttcc tgctacgcca tttaccaaga tattttgact tttcacatcc cgaatgattg
    38221 tgttttgttc cgattggatc gtagcagtga tagccttcat ttcattggtc tcatcttggc
    38281 ctaagacttc taataatacg tcatcttgaa tagctacaga cgtatcaaaa aacttgacca
    38341 aacgatctct ttccaaaaga aattgtcgtc tttctttaat aaccgtatcg attttatttt
    38401 gacgaaccgt ataagaagat ggaccaatca tgttattgta aaaaagttcg gcaattggtg
    38461 aacgccaatc ataaacaaga ttttcatctg catcatctgt gaaatttgct gtaccgatat
    38521 aaaaggattc ttttggctca ttatccagaa agtctacaac gacttttcca aagtagggac
    38581 ttttcaataa acgttcgatc tttgctagct gattttctgc gtttttctgt ttgatattca
    38641 tctgatcgat ttctctattt ttcatttcaa tcatcgaaaa agtatccagg ttatctaagt
    38701 aactgtcaaa attcaatcga agctcgccag ccatttcttt caacgactgg tttccttcta
    38761 tttttgccgt atccatcgat tcccgcagtt cgtttttttt atcaattagc ttttgataca
    38821 cgttcttcag atatgcttct tctaactgtt tttgtgtgtt gaccatacac attctcctct
    38881 ttttttaaag tggtggaacc gattagttta cctcttttaa gagtcgaatg caagcttttt
    38941 aacgagtatc atttgttagg atatatcagt tcttcaggtc ggacagtttg atataaagaa
    39001 aatgcaccat caaggttttt tacgtggtag ccagactgct tcaagattct ttccgctaga
    39061 tagctacgta atccgctatg acagctgacg atatattctt gttggctgtc taattcattt
    39121 aatcggtccc gaagttcatt caaagggata tgtttggctt ccttgaattt gcccttttcc
    39181 aattcttctg ctgttcgcac atctaataaa atttttcctt ttgctagttc tgtcggcaat
    39241 tcatgccatt gtacggtttc actaagccct tctgcaatgt tcattgctgc atatcctagc
    39301 atgtttactg gatctttggc tgagccaaat ggcggtgcat acgtcaattc taattccggt
    39361 aaatcgaaga tcgtcaaatg ccctttgatt gctgttgcta aaatatcgat ccgtttatcc
    39421 acaccttttg ccccaacacc ttgtgcacca taaatctcgc cagtctctgg atggaagatc
    39481 aacttcagta aaatatctgt tgcttctgga taatagcttg catgatcttt tcctgataca
    39541 tgaatgactt caaaagacag ttcgttttct ttggctgttc tttcacttaa accggtggat
    39601 gcggcagtca ttccaaacgt tcgtataatt gctgttccaa taccgccttg atttcttcga
    39661 gaaattccgg aaatcgtgtc cgcaacttgt ctaccttgac gattggctgg tgaagcaaga
    39721 gaaataagtg catcttttcc agtgatttgc tgttttacaa cgatagcatc ccccaccgca
    39781 taaatatcag gaatattcgt ttgataacgt tcgtctacta ggataccccc gcgtatgcct
    39841 aattcgattc cagcggtcac tgctagctgg ttatcaggac gaacaccaat ggataaaata
    39901 actaaatcag cagggatggt acgcccatca tccagtcgca atcgtttccc gtggtcttca
    39961 aatccagcga cagcatgaga agtaatcact tctactcctt gatgagacaa ttctttttct
    40021 ataaaagctg ccatttcttc atccagtgtt ggaagaatat gtggtgcttg ttcgatcacc
    40081 atgacttcta aacctcttct ttttaggttt tctgccattt ccaatccgat gaatcctgca
    40141 ccaacgatca cggcacgctt tggctgtttt tctaatgcat gcatcacttt atcgatatct
    40201 ggtacatttc taatagaaaa aacattgtcg gcttctgtta tccctggaat cgatggaaca
    40261 actggttttg caccaggaga taaaaccaat gcatcgtact gttcaatgtg tttttgaccc
    40321 tcatgtacga cttctaccgt tttgttttcg ggaaagatgg ctgtcacttc atgatttgga
    40381 cgcacatcta aacaaaaacg agcggataat gattctggcg tttggacaag aagattttcc
    40441 cgttcactga tttctcccga aagataataa ggcaagccgc aatttgcaaa agaaacatac
    40501 ggtccttttt caaaaacaac gatttctgca tcttccatta atcggcgaag ccgtgtagca
    40561 gcagacattc cacctgctac acctccgaca ataacgattt tcatcttatt tccctcctac
    40621 tgttcgatca aaccattgat tcatgccacc acgtacattc actacatcat aaccagattt
    40681 ctttaattct ttagctgctt gtttactcct catccctgat tgacaaatca catagacggt
    40741 cttttctttg tctccatcat atctgtttat actttgtaat ggaacatttt tagctccttt
    40801 tatatgcccg ccccggtatt ctgcaggtgt tctaacatca agtaacgctg gattttccaa
    40861 aagcttttcc tttaattctg ggactgttat cgattttatt gattgaaata gcaaattcat
    40921 tttctgcacc tcatttacat ttttataaat acctcatggg gtatattaaa caggagcttt
    40981 attaatatgt caaccagaat gactcttcat ttttttcact actttttata tttgcataaa
    41041 ataccgataa ggggtattat ctaattataa aaatagagga gaatgtgtta tggagattga
    41101 taataaaaat atcctgaacc gtttgaaacg tacagaggga caaattcgtg gtatccaaaa
    41161 aatgatcgaa gacgaaaaag aatgtatgga tgtcatcact caattaagcg ctgttcgttc
    41221 tagtattgat cgcgtaatgg gcatgatcgt tgcagataat ctgaaaaatt gctttgagaa
    41281 acctgatagt aatccagaag aacaagcggc taaactagaa caagcgatca agatgattat
    41341 taaaaagtaa aggaatgatt tcaatgaaag tcgttttcca tattgatgaa ttagaaaaat
    41401 ggtcagaaac agggaaaaac gtaaaaaacc tgataaaagc ttctccagaa acgacgattg
    41461 tcgtatctgt aaatggcatc gcgattaccg gttatctaga ctctgccaat gcagaattct
    41521 tagatttgca aggagtcgtt tttcacgctt gcgccaatgc tatgcgtgct aatcatattt
    41581 cagaaagttc tttacctgaa caagtaatcg ttgtaccagc aggtgtcctt gatttagttg
    41641 aactgcaatc ccaaggttat gcttatatca agccttagtc agtagaggtt gcgacagaag
    41701 tgatcagctt caagaaattt cggcttattt ttcgaagaag ctacttctgg aaaaccgtga
    41761 atcaaaggtt gtgaaaacgc tgtcctgcat caagtaataa gaacagccaa acaaaaatag
    41821 cttctcatat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt tgaacaccgt
    41881 ttaaggaaga ggttgtgaaa tcagcggttt gacctaagta ttagagaaaa aaacgggaaa
    41941 atagctcctc atattttgcc gttttttgag ctaataccga aggtcagctg attgaacacc
    42001 gtttaaggaa gagattgtga aaaagtcgct tagtttcgag tattaagaaa aattttgtga
    42061 aaatggattt ctacattttt gcataaattt ggcttaatac cgagaaactg gcttttgaat
    42121 accgtttaag gaagaggttg taaaatcagc ggtttgacct gagtattaga gaaacaaacg
    42181 gaaaaatagc tgctcatatt ttgccgtttt ttgagctaat accgaaggtc agctgattga
    42241 acaccgttta ccaagaggtt gtgagcctac catttaactc cgaatcacaa gaaataattt
    42301 caaaaacaac ttctcctgtt tttggttcgg ttggcttatt atcgagaagt agctactggg
    42361 agtctattta tcaaaaaaag gaatgcgaca taggtcacac ccctttttta ttttctttga
    42421 aacatctttc ggtactcgac agcatacaag acaaaagatt gtaaaagacc gtaagtgatg
    42481 acggcaaaaa tgactctcac ccacagcgtt ggtaattctg ggaaaagcag caaaaggatc
    42541 atgccaacat agatgacagc agtcgctact ttgccatacc acttcgctcc acttaatttg
    42601 atatttttag atagcccgat taatccagct acaaacataa agccttcttt tatcaagaat
    42661 agaccaaaca acagccaaag ccacggtcga taccatgcca tagacaaaat cagaaaaagt
    42721 tgtgtcaatt tatctgcaaa cggatcaagc accttcccta agtctgttac ctgattatat
    42781 ctccgagcaa tgaccccgtc tagataatca gacaaacctg agacaacaat gaccgctcct
    42841 gctatataaa atgactgtct cagcacaaaa taaagataaa tcggcagcaa aaaaatacgg
    42901 aatatcgata aaagattcgg aatcgtttgt atttctttac gccagtctgt gcttaatttc
    42961 attttatcgc cctacctcct cagcactctt ttctttttat tttagcttac acggggaata
    43021 aaaccaatga tttcactgtt tttatttttc tttacagaca ctgatattat gagctaattt
    43081 gagataatca cttgctgttt tcatcgttta ctcttctttc ttcctgtcgt ttgcgcattt
    43141 cttttactag tactttatga gctttttttg atcctcgctc taggtcacgc tgccgtttac
    43201 gtgttttata atcgataaac agactgtcta aatcgtaacc tgtcgggtac agatcttctg
    43261 ctgaacgcac cagacgaaca cgctgacgag gcacgtggat tatttttttg tctaaatata
    43321 catcaatcgt atcttcacct atatcttcat aaactaacgc ttctttttgg tattcattga
    43381 caaatatccg atcacctttt gcaaagagct gacgttcttt tttattctcc ttcctatttg
    43441 taactgctgt cttaggaaga aattcttttt tctgtgtccg ataggctttt tccgccaagt
    43501 aacgctctgc ttgatggatc aatttcatcg acatatccat tttatgagca atccacaaag
    43561 cttggctttc tcctgtttct tccaacccgc aactgatatt taggacgaag tgcttcccga
    43621 tcgaaagcca tagcagccgg cacaaaatct tcatgatctc cggcgaattt cttgatttct
    43681 ccataatggg tcgtggcaat gatcaatgcc ccttgctcat acatagattc catgattgcg
    43741 atcgctagtg cagccccttc atttggctct gttccactgc caatctcatc taaaagtacc
    43801 aacgtattcc tttttatctt tttcaaaata gcagcgatgt tttgcatatg accagaaaat
    43861 gtactcaacg cattttctaa attttggtgg tcaccgacat cgacgaaaat ctcatcaaag
    43921 acagcaagct ctgtcccttc ttttgccgga acttgcatac cgaacatcgc catcaaagtc
    43981 aataaaccga ctgtcttcaa cacgactgtt ttgcctccgg catttgctcc ggtgataatc
    44041 aagcctcgat agtctttacc gatttcaaca tccaatggta ccgcatgctc aggtaaaaat
    44101 ggatgtctgc cttgcttgat aatgatatgt tccgatttat tgattctagg tgtgcttcca
    44161 ttgatttctc ggctaaattt tgcccgagca aagatgatat ctaacaccgt gatcgtttcg
    44221 atcaataaat cgatcacttc ttcgttttct gcgatagcac cagtcaatgc cgccaggact
    44281 tgatattctt cactgatttc ttcagctttt aacaactgat agtgttcatt caatttagaa
    44341 atcacagttg gttcaataaa aaccgtcgtt cttttatttg attcatcgat aatcgttcca
    44401 tctattttat ttttatagct ggctttgata ggaatcgtat agtattcgcc tttttgaaca
    44461 atcattgctt cttggatcat ttctttgttt ttcggatgac gcaagaattt cagtaatttt
    44521 gactggattt ctttttcgat tagttgtaat tgtttgcgta ctttacgcaa attacgtgac
    44581 gcgtcgtcac tgactttatt attttttatt ttctggtcaa tcaactcttc tacatttatc
    44641 aaatcaggaa gatgtttgct ataagcaaac aacaagggtg tctggtattg attcttatca
    44701 aaaaactttg tgatcatccg actgcttcta agaaaatccg catattcgat caaatcggtt
    44761 ggctgcagaa tcaacccttt tttgacttgt tctgtcagtg catcgatcct cggcaacccc
    44821 ataaatggaa catgctgact gctttctaag atcaagcgtg cttctcttgt ttcttcttga
    44881 cgatccaaga cagtttgtag gtttgtcgag accgtcatat cgctgattcg ttttttgcta
    44941 tagtttccaa ttgctcttgc ttggatttcc tttttgatcc gatcaaattg taattgacta
    45001 atcatttcgt tgtccatatt ctctcctttt cttgaagaga tacctgtccc aaaataaata
    45061 agggcctaga gataaataaa aggatagaac acagcttaaa aaagtcatgt cctatcctta
    45121 ttagaataca aagatattgt tttcctgaca ggtaccgttt cataagcaca ccaaataaac
    45181 tttgtttatt ggctattcga cttactgatt agataccagc tacactcaca aaacataccc
    45241 cattcttcta ggtcttattt attttccact taactatagc aagacacatt ttggttgtca
    45301 aactttagta tgttttatag atttacacca ttaatgaata gacacctacc gcgataattg
    45361 ctccgatcat tggacctgcg attggtaccc atgaatatgc ccaatctgaa gttcctttat
    45421 tagctattgg caataccgca tgtgctaatc gaggaccaaa gtcccgagca gggttgattg
    45481 catatcctgt tggccctcct aatgaaagac cgatggctaa gatcaatcca cctacagcga
    45541 atacgttcgt tccaggtgca aattcgtttt gtccaaaagc tagcaaccca agaactaata
    45601 caaatgtacc aattaattct gtgatcacat ttgctggata attccgtata gcaggacctg
    45661 ttgcaaacgt tcctaaaatc gcgctttcat ctttcgttgc attccaatgt ggcaaataag
    45721 aaagccaaac aagaatggcc cctgcaaaag ctcctaaaac ttgcgcaatg atgaaaggaa
    45781 cgacaagatt ccaactaatt gcccctgtca tcgccatagc tagagagact gcaggattca
    45841 aatgagctgg gcccatgaat ccagaaatat agacagccat tgttacagcg agtccccaac
    45901 caaatgcgat gacaatccag ccagaagcct gtgctttact tttgtttaaa ttcacagccg
    45961 cacacacacc atctccaagc aaaactagga tcagtgtccc aataaactcc cccatgattt
    46021 gagtcatatc actgttcatt tatttctccc cctttagttc ccgcagatct gattctgcaa
    46081 tcaatgcttc taaacgttta gtctgttgcg ccttctcctc ttctgtccat tcaaaatatc
    46141 cagcaattgc atcgatcaca ggttgcttga tctcatcaag ctgatctcgt tcaaacaaca
    46201 gatgatttgt acgacgaatg agataatcgc ctggggccaa aaccatttct tcttctaaac
    46261 cataacgtaa ccgagctgac tcagcgagac tcaaaccagg ataaggtgcc atttcttttg
    46321 ctaattcaaa gatacgtcgg gcattagtcc cgtaaaaatc agcgatataa gtagcatctt
    46381 cttcctctaa accggctgct actccttctt ttgctaattc tgtcactgtt tcttctaatt
    46441 tagttggatc gaagtttcca cctgaaatct gatatttttt agagtcgatt tctttcgtct
    46501 ctattccgta ttcttctttt aataattggc gtatcaatcg caaagctcct tctgccatct
    46561 tacggtaatc ggtgattttc ccaccagata aagtcagcaa accatctggt tctctttcta
    46621 aagaactacc tctggaaatc gtagaaggtg ctttttcatc acggctgttt tccaaatggt
    46681 tcaacacgtc ttctacttca gcacgagaaa ctttgttttc cttatattca cttactgtat
    46741 cgacaacttt attgaagctc ttgtctgaaa tcgatccatt atctccacca ttgtaatcag
    46801 aaccagaatt accaatcaac agtggacgaa gtcctgccca gcttgcttcg atatcattca
    46861 atgtgatatt tgcttctgga tagcgatgat tgatcacatc caatagataa tctacatctt
    46921 cttgtgtgac tttcggatcc gtaaaatctc cttggtaatc cgtatctgtc gtaccaaagt
    46981 aagtcttgtt ttctcttgga atagcaaaaa ccatccgccc atcttgcttt cctgtatcga
    47041 agtatgtggg ttgcggtaca ggcagttttt tcgcatctac aactaaatgg atccctttag
    47101 ttggacgcat tttaggagag actggacgcg taaaattcaa gtttcgtact ttatctaccc
    47161 aaggaccact cgtattgatc actaattttg ctttgatttc gatcacttca tctgtcagca
    47221 ggtcacgagc tttgacgcca acgatttgat cgccatcata taaaaagcca accgctttca
    47281 ttttacttac tagataagcc ccatcttcgg cagccttttt gatattatca atcactaaac
    47341 gggcatcatt gttgcggaaa tctagataga cacccgcgcc ttttagccct tcttttttca
    47401 aaaacggttc tctttccaat acttcttctg gtgtcagcgt ataattctca tatttggttc
    47461 ctgtcacatt tgccagtttg tcataaaggt ccattgctac tttgaccgag aacatattga
    47521 aggttgttgc tccttcgccc tcatagattg gcaaaagcat tggatctggt tttgggatgt
    47581 gtggggcaat actttgtacg actgcacgtt caccaactgt gtcagctact acttccacat
    47641 caaatgtctt cagataacga ataccgccat gaacaagttt ggtcgagcga gaggaagtcc
    47701 cttctgcaaa atcctgcatt tcgatcaatc ctgttttgat tcctgatgct gctgactgga
    47761 ctgccacacc ggcaccagtg attccgccac cgatgatcaa cagatccaat tcttcttgct
    47821 gcattttttg aatgctatct tgtcttgtct tgtttgaaaa catatggatt tcctccttat
    47881 tcaaatgctt gggtagcttt tactgctttt ttccaaccgt tgtaaagttt ttctcggcgc
    47941 tcttcctcca tttgaacttc aaatagcttg ccagcttcat aaaattcgcg gatctcgtct
    48001 gtatctttcc aataaccgac agctaatcct gctaaaaatg ctgcccctag cgccgttgtt
    48061 tccaagtttt ctgctcgttg gatcggtaca ttcaagatat ctgtttggaa ttgcatcaga
    48121 tattcattgt ttgctgcacc gccatctact ttcaatacag gaatcttgat tccagtgtca
    48181 tcttgcatcg tatcgatgat atctctcact tgataagcaa tcgactgtaa agtagcttta
    48241 atgatatctt cttttgtcgt accacgtgtc aagccaaaca tagcccctcg tgctgcctga
    48301 tcccaataag gagcacctag cccaacgaat gcaggaacaa cataaacctc atcttcgctt
    48361 gtagagcgtt tcgctgcgtc ttctgaatcg ctagcttttt gcaacatttg aagtccatct
    48421 ctcagccatt gaatcgaaga accagccaca aaaatacttc cttctaaagc atagtaaacc
    48481 tttccattta tgccgtaacc aattgtcgtc aataaattat ttttggataa ttgcggtttt
    48541 tcaccggtat tcatgacaat aaatgaacct gtaccataag tattcttgac catgcctggt
    48601 tcgaatgcca tttgtccgaa taatgcggct tgctggtctc ctgccatccc tgaaattggt
    48661 gcttcgcttc cataaaaatg ataaccttgc gtataaccat aaacttctga gttagaagtg
    48721 acttttggta acatcactcg aggaatattt agtaaatcta aaatctcctg atcccaatct
    48781 agctgatgga tattgaacaa catcgtccga ctggcattcg agtaatcagt aacatgtgct
    48841 tgtccatcgg tcagtttcca tactaaccaa gaatcgatcg ttccaaacat caattcgcct
    48901 ttttcagctc gttcttgcgc gccttctaca tgatcaagaa tccagcgtat cttcgttgct
    48961 gagaaatagg catcgatcac taaccctgtt ttttcgtgga aaaattcttg atagccttca
    49021 ttttttaagt tatctgcaat tccagctgac tgtctggatt gccaaacaac tgcatgatag
    49081 attggacgtc ctgtatcttt ttcccatatt actgttgttt cacgctggtt cgttatgcca
    49141 atcccagcaa tctgatttgg tttgatccct gattcgatga acgctccggc aataactgac
    49201 tgtacagaat tccagatttc atttgcatca tgttccaccc aactttcttg cgggaaatat
    49261 tgcgtgaact ctttttgaga actgccgatg tgtcttcctt tcttgtcaaa gataattgct
    49321 cgtgagctag ttgtaccttg gtcaatcgcc atgatatacg ttgattctgt cattgtgatt
    49381 ccctccatta tatgcaaacg ctttctttaa ctactcttat catactactg ttttaaaaaa
    49441 agaaactgtc aaaattttat tctttttttc tttttttgac agttttttat tatgaagcta
    49501 ttttttaatc aattcttttc ttttttcagc gtctctattc ttcttttcaa tcgaataatg
    49561 tcgtaaggtg acgcaaattc tgacagataa tattcacact gttttttgtt tctctggcaa
    49621 aatgtgatca ccaaatcata ttctttacct tcttcataac ttccaatctc aataccgccg
    49681 attcccctca gttctctgat cagatattgt tgaaaagcaa tacgataaat cggcagactt
    49741 tctaaatcga ttccaatcac tactggtttt gcaatataaa aatcgatcat caaaagaaca
    49801 ttggcatact ggatcatcag gtaactaagc tcactatctt cagctctttt cctcggcaat
    49861 tgctgcaccg ctgtttcctg taatttcgcc agtaactgtg ttaaggaatg cccgagcatt
    49921 ttctgctgct gttccaaaag ccgatcacgc tcatagactt cgatctttcc aacaaagaaa
    49981 aaccattcat tgttgatctg ggaaatttgg tagcctactg ccttttcttc tttgattttc
    50041 aaacgacgag gacgataatg ccataacatc gtttcccgaa tgtaagtatc taaaacagcg
    50101 gttggtaact ttttgctccg tgtcaaatca tactgataaa atatttcttc gtctactatc
    50161 gaaaaagaaa caaaaaagct gtaaaacatc attgtttcgt atacattcag ttctgctgct
    50221 gttcgactaa gatgcatcac gatgattgga tcgattgctt gataaagccg gtccgactga
    50281 tagagtaatt tcttttcttt caaagttgcg tacgtacttt tttcattcaa tagtcttttt
    50341 ttcgtaatcc cgagccagca agcaatctgt gcttctgctg atgccgtaaa cgttgtttct
    50401 aatacacggt ccaatcctag aatgaacggt cttttttctg gtgtattttg caaaaaaagc
    50461 ggtcgctgat cttccgggat atattggaat agttcataat aaaaatatcg tatctgtagc
    50521 tcttctccgt ataattgacc gtttttgatt tgtaatccaa attcctctaa gagctggttc
    50581 aattctttga tctttcgaaa aacagaagac tcactgatat taaacgctgt cgctaatcga
    50641 acgatggata cttgctgatg ttctaataaa tagacgagca tcttaaactt caagctttcc
    50701 tgcaataaaa acaatagaat tttttccaaa cttacatctt cgtccaacac aagcagcgcc
    50761 tgatactcat ttcgctgtac ttctactttt ttttccatca ttcggccaat caattcaata
    50821 tcttccaaat attgatcaaa cgaggctttt gacagttgga catgctctct caaaccattg
    50881 atagaggctg ttcccccttg cagaacaagg tttcgcaaaa tcaggatctg taactgctct
    50941 tttctttcta ataatgcttc aatcttcata ggcagtattc gccacctttg accacaccat
    51001 atctggcaca cggtattctg gctggaaaaa tagctcatgt tcttctaact gttcaaacgt
    51061 ccatccttct tctactgcaa ttgtcagttg gtcaagaagg tggaacatct cttttttgct
    51121 ttggagctgt gctccaagaa tctttttttc agaatcaaat agaaatttga gtttaacttt
    51181 gctttgattt attgctgtaa gcttgtagtc tacgtatcct gtttcaattt tttggggata
    51241 aaaaatgctc tcttcttctg tcaaacctac gcttcctaag aaatagccaa accactgatt
    51301 gccgactgga cgataggttc cctgatcctt tgtctgtgag ccactaattg tcttgctgac
    51361 atttcgtgct gtacggacag cgttatttac tagagaaaca tacatttttt catttgttgg
    51421 acgaaaagtt acttggatcg catcgccaat cgcataaacg tctttttgag acgtttgcaa
    51481 gtagtcatct acccagatcg ttccatcatc attcaatgtt aattgttctt cccacatctg
    51541 attgtcggga cgagaatgat tagccagcaa aacaagatca tagttctcct ttcttttttc
    51601 cgtctctaca atagcggttt cattttcggt caaagacaca acttgttctt ctaaaaaaag
    51661 tgaaagccct tgatttttca tttcctttac taacggttct gtcatttcag gatctagata
    51721 acgaaaaaga attgactttc ggctttcgta aagatggatt tgtttttttc ttgatgccaa
    51781 cccttcagct atttcgattc ctgcttgtcc tgcaccaata attgcaattt tctttgcatt
    51841 catgatcttt tgctgaagag ccgttacgtt ttgtatcttt ttaactgggt gaataagcgt
    51901 tgattctgca gaaatatttc gaaacttttg atttgaacca gtcgctagaa tcaaacgatc
    51961 aaaatccaat ttttttcctc ctgctaaaac gacttttttt tctttcaatc ctattactgt
    52021 cttttctgtg taaacatgga ttcgatagcg gtcagtcagt tcttctttcg tgatccaaga
    52081 aagttgtttt tcactggtaa cctttccttt taatatcaaa ttgaacccgc tgggaatcca
    52141 tcctaacttc gattgctttt caatcaaata tatttcactt gttggcatca attggcgaag
    52201 ataaatagcc gcatgaatcc ctgcaaacga cccgccgaca attacaatgt tcatctgcat
    52261 tcctctttct tataaggtgt tctactgcta acttctcaat cagaaaacac agtattcata
    52321 actcgctttc aaccttatga tacatagcga tgcagcagaa tcaaccctct ccatcatacc
    52381 gtgttctagg tctgcttctc aataatgtac tagtggacct aattgaagag tatcatttct
    52441 gaagagatgt ttcaaaaaat gtactcttat aaaagaaaaa aactcgcctt ttacgtacct
    52501 ctgtccaaat aggaaacaga aaagaacgaa aagacgagtt ttagcgtgtg taatgtaata
    52561 gttagaatag acacatcatt tatttttaat tctttaatgc ttcaacaact gcttcgccta
    52621 attgatgagc agattgagga ttttgccctg taagaagccg cccatcaatt tgaaccactt
    52681 ctgaaaaagc tgctccagac tgatagtttg ctcctttttc tttcaaagca tcttctgcta
    52741 agaatggtac ttcattcgtt gtaccatttg cttcctcttc ttcattactg aacccagtca
    52801 ctgtacgtcc agctaaaata gattttccag actcatctgt aactggcaac aatcctacaa
    52861 caccgtgaca aacagctgag accagccctt catttcgata gatttgtgaa gcgactttcc
    52921 caagatctat tgcttctgga aaatcccaca ttgttccgtg gccaccagca taataaaccg
    52981 ctgcataatc atttgcatcc acatcatcag gacgtaaggt atttcccaag gcccgatttc
    53041 tgaaatcttc atcttcataa taggcccaat cgatttcatc catattcaaa acactttgcg
    53101 gttctaaagg tacatatccg cctttaggac tgacaaaatc tgcatcgatc ccatttttta
    53161 ctaatacatc ataaaaatga gtcagttcac ttaaccacaa acctgtagga cgctcgatct
    53221 tttcgtactt ttctacattt gttaatacga tcaatacttt cattttccca tcctctttct
    53281 ataaaaattg cgttattgat aacgtgcttt caagaaatta tataatgggc ttggcaaata
    53341 aagctcttta tatgcttctt caaaaggttt cgttacaaat tcatcctcac ggttttccaa
    53401 taatttctct gcccagtcag gatcgacgat catttgctgt ccaattgctg caagttctgc
    53461 atatttcaat acctgctcta catcttcgcg attgcggatc ccaccgacac caactaaagg
    53521 gatctttcct tgaatcgtgt tatggaccac ttcaagaatc gatttatcgt tgtatttatc
    53581 agaacgagct attcgatcat acatatttaa tgaaacatgc agataatcta gttttgactc
    53641 acgtaatcgt tcaagaagcc agatcgtgtc ttcaaaacgg atacctggtg tttcatattc
    53701 ttctggtgag aaacgatacc ctacgatgaa tggtttttta gcatattgtt caaccgctga
    53761 gaaaaccgtt gttaataatt cttcaataaa acgataacga ttttccaagc taccgcccca
    53821 ttgatcctct cgtctattcg aatgcggaga gaaaaattgt tggatcaaat acgtatttgc
    53881 tccatgcaac tcgattccat caaatcctga ttcaatcgct ctacgtgtgg ctttgccaaa
    53941 tgcttggatt gtttcaacga tttcttcttc actcattgct cgtggtgttt ccgcatcagg
    54001 acgttttgct gcaactgcac ttgcagatac aggctgttct ccagataaag ttgctcgact
    54061 tgtcattcgt ccaccgtgga aaatctgaat aatcgctttt gcgccttctc cttggattgc
    54121 tttcgctagc tcacttaatc gaggaatcat ttcatcatga gcgatgctga gttcacctgg
    54181 ccagcctttt ccgatatctt ggacatttgc agcaccagta ataacagcac caagaccttt
    54241 agaacgttgt ttataataag tgatctcatc ttcggtgatc actccattga aaaagctgag
    54301 ttgtgtcgtc ataggcgaca gcatcaatcg gttcttcaat tgaactcctg aaggtaaagt
    54361 aattgattga tcaaattgtg acattgtcat tcctcccata attcgctctg attaacctat
    54421 cgagaatcat ctatcattaa accactcgat tagttgtaca tgcaactaat ttgcttaaaa
    54481 aattttattt tttttgtaac ttatctgttg catcattcat tgtctgggct aattctttac
    54541 ttgcttcatt tcccaaaact gctttgtatg actgatgaag ttcttcccag ctaccatcga
    54601 cttccttagc aaattggcgt ccttgttctg taagataaac taatgacaag cgaccttcgc
    54661 taactgtttt gacgtatcct ttatattcta atttttcaac aaaacgagca atcgttgatg
    54721 gggcggaata gagcatttgt gcaatatctt tttgtggtat tccatctttt tcttttaata
    54781 tcaataaaat aaaaccataa gttggtgcca gacctgtcct tctaaacgct tcatcagcta
    54841 atttattcaa catgcgatct agctttttca cgctaaagaa aagacattca tctaacgctt
    54901 tttcaattgg cttttccatt tcatcccctc cattggcgta catatcatag tatgattttt
    54961 attttttgtc aaaaaacacg gaataatgtc cgcctcctct gtctagattt gaaaaaaaga
    55021 agtagccatc ttcaaagaat ttcggcttgt tttcgacaaa actccttctg gaacaccgtg
    55081 aatcagaggt tgtgaaaaag tcgtttagtt ttgagtatga agaaaaattt tgtgaaaatg
    55141 gctttccaca tttttgcata aatttggctt aataccgaaa aactggcttt tgaacaccgt
    55201 ttatatcaga ggttgtgaaa aagccgtcct gcatcaagta ataagaacag ccaaacaaaa
    55261 atagttcctc atattttgtc gttttttgag ctaatgccga tggtcagctg attgtacacc
    55321 gtttattgag aggtcgtgag cctgccgttg aactccgagt cacaaggagc aatttcaaaa
    55381 aacagcttct catgttttat gactatggtg acttgtgatc gaggagttgg caggagaata
    55441 ctgtttattc gtaaagaagg ggctgtgaca agacttttgt cacagtccct tatttccttt
    55501 tattatagga tttcgccatt tgattggatg acttgtctgt accaatcaaa tgattttttc
    55561 tttaaccgtt tctttgtgcc attcccttcg tcatcttgat caacatagat atatccataa
    55621 cgttttgaca tttgtgaagt agaagcgctg acgatatcaa tgcagcccca cgacgtataa
    55681 ccaaataaat ctactccatc tttgatagct tccttcatct gctcaatatg ctgcttcaaa
    55741 tagtcaatgc ggtaatcgtc ttgaacggtt ccatcttctt ctactttgtc tatagctccg
    55801 agtccgtttt cagctatgaa cagtggtttt tgatacctat catataattg attcaaagca
    55861 attctcaaac ccttaggatc aatctgccag ccccattcac ttgatggaag atacggattt
    55921 ttaattcctc cagttattaa gtttccttgg accccttccc aattttctgg atgagcactg
    55981 actgcactag acatgtagta gctaaaagaa acaaaatcaa cagggtaggc tgctaagatt
    56041 tcttcatcac ctacttctat ttttaagttg acaccttttt cttcaaacat tcgttgcgta
    56101 tacgctggat aatatcctct tgcttgaaca tcactaaaga acaaagaagt tctttgctgc
    56161 tcaattgttt tttgaatatc atccggatca caagaatacg gaacaagaag ctgatagctg
    56221 atcatacaac cgacttgtga acctttgata atttcatgac aagcttttgt agctaaagca
    56281 cttgctataa actgatggtg tgcaccttgg tatttcgctt gttccaaatg gggatggttt
    56341 tcttcaatta ctcctacgct aacaaaaggg tgatgtttta cacagttgat ctcattgaaa
    56401 gtcatccaat attttacttt atttttatag cgtttgaata ctgtttcagc gaaacgaacg
    56461 taaaactgaa taagctttcg attaggccat ccaccatatt ctgtaaccaa atataacggc
    56521 atttcataat gggaaagaga aacgactggc tcaatcccat attttagaca ttcgtcaaac
    56581 acttgatcat aaaaaaataa tcccgcttca ttgggtgttt cttcatcacc atgaggaaaa
    56641 attcttgtcc atgcgataga catccgatag catttaaaac ccatttcagc aaataaacgg
    56701 atgtcttctt taaagtgatg atagaaatca tttccgtgtc ttttaggata ataatacttg
    56761 ctgttgggat cctgcgccgc ttttacttgc tgatgcgtca tcatatgcca ttgatctgtc
    56821 catttttctt taggtaaatc gctgtcgaat gtatacacat cagacacaga taatcctttt
    56881 tcatctacat cccatgcacc ttcacattga ttggccgctg tcgctccgcc ccataaaaat
    56941 ccttctggaa attttttcat atcgatcccc ctaaacttgc tagttttctt gtttgattat
    57001 ttttcttatg actagtaatg atatttttga atctactact atttgtaaca ataaccattg
    57061 tggtcggatc atatccctct ttgattaatt cttgcaaatc tacttccatc aataaatcgc
    57121 ctttacgtac tttttttcca tcagatactg cactttgaaa gtatttgcca tttaaattca
    57181 ctgtatcaat accgatatgg atcagtatct ctgctccttc ttcactgact accccaattg
    57241 catgtttcgt tggaaaaact gttgaaactt ccccgtttac agaactgtag atttttccgt
    57301 ccgttggaat gatcgcaaac ccttctccta aagatccact agcaaatgtt ggatcgttta
    57361 cttcagataa atcaattatt tcacctgctg caggagtact taacactata tcctttgagg
    57421 attcttcttc gatttcatcc ttgtagccga aaagaaaagt tagcatacag gaactgatca
    57481 tcgctaagaa ataactagca actagccaaa caaatccttc accaatataa atcgggaaag
    57541 acaaaatact tcttgtagca actgccaaag caccggctcc tgcggcacca gctactccac
    57601 caaatatagc tccacatata caagcaatgt aaaatggtcg tttatattta agagtcacac
    57661 cataaacagc aggttcagtg attccaaata atgctgtgat aaatgcagat aaagataaac
    57721 tttttacttt cttatttttc gttttcaaaa ataccccaag tactgctcct gcttgcgcag
    57781 ctacggcagt catacatgct ggacctagcg tatcacgacc gtagaaagaa agattgttgg
    57841 tcattactgg tacaagtccc caatgtaacc caaaaatcac taacacttgc caaaatccgc
    57901 cgataacagc accagataaa acagggctaa agttataaac agctaaatat ccagctgcaa
    57961 tcagctgact tgcataatct gcaattggac ctacaactaa taaaataatt gggaccatca
    58021 cgatgataca aatgaatggt gtcaataaat ttcgaatact ttcgtgcaag cttttgcgaa
    58081 tcttaggctc aatataagaa agaacccata cagctaaaat tgctggaata accgtacttg
    58141 tataccttgc tagaatcacg ggcatcccta gaaatcgcaa ggttatgcta tcactatatg
    58201 cactgacaat cgtaggataa acgagagctg ctgcaataac catagcgatg aaacgatctg
    58261 tattgaactt ttttgcagca gtatatgcca aaaatatagg caagaaatag aaaaatgcat
    58321 cagctgctgc attcaaaatg atataagttc ctgattcagt agttaataaa ttcaaactcg
    58381 tacataaggc gagtactcct ttgatcaaac cacttcctgc caagacgcct aaagtcgggg
    58441 caaaaacagc ggcgatcatg tctataaaag agtttaaaat gccttttttc tcagttcctc
    58501 tctttccact agatgcatca tcttctagtt tcatttgttt ggataatacg tcatacactt
    58561 catttactgc atttcctact acgacttgaa acattcctcc agcttcgact acagtgatca
    58621 caccttctag ttgctctacc ttctccttat ctgccttctt attatctttt agggtaaagc
    58681 gtaaccttgt tgcacaatgg taaacattgc tgacattttc ttcgcctccg acaaatcgga
    58741 caatatcttt cgctaattgt gaatagtcca tttttacttc ccccttgtta attaatgccg
    58801 tagcaatcct tcttacaaga taagtatagt tcttagaaaa cggtttctcc attcaattag
    58861 taccccttct aatagcgaac gaaactgtac aatagtgtgt atggtttact tagccgagca
    58921 aatcactcac tgcttgaaag aaaacaagta tatcgtttct cttatagtca aaggagacaa
    58981 aaaaaacacg cttgatcttc ctttgctgat gtataagtgg tatctcaagc tgatactctg
    59041 tgatttttgt ttctacttgg cttttgataa gacagcacaa caaagtctcg gcatttaacg
    59101 gaagcataac taggtcagaa ctaggagaga ttagttgctg aatggaatct atctttttat
    59161 ggatttttat ttgattttct tctttgtagt aatgatcaag cagttttgtt ttcttttttt
    59221 cttcaactat ggtcagcttt tcacgcaaaa tctgataaat ctcccaagat tcaaactcat
    59281 ctagaacact aggtagataa atcaaatcat cccactcaaa aataagctct tgctcagtag
    59341 tcaaaattgc atcatattcc gttattttgt ttgattgatt tttgaaaaga tacactggtt
    59401 ctatccggca ttctttgatc cacatgttca tactttgttg aatctgtttt tttagtgtat
    59461 tcaaaatact aattggctgg ttactaacaa tcagtatctc cccttgtttt cgaaaaggat
    59521 tcaacgcttc ggcaagatac aaaacaaaat aagcgctttc agctaaattg ggacgtaatt
    59581 gaaaatgtat tgggaagaaa cgccgaatta aataaatttc taaaggataa cgggagatga
    59641 tcttttgtac aaaatgattc atggtattat gtccggcatc catcctcgtt ttcatttgtt
    59701 tgatatgggt tagcaaaaat tctgtttcat ggaacaataa cgaaacagga agatctaaaa
    59761 aacgaataat cgtttgctca aatgctctta gattcttctc tatttctttg tttttttcat
    59821 cattaatcat caaataattt aactctaata gtcgattttc aattgcttgt ttttcttgat
    59881 tggaaaaaga atagggtagt tctgatgata acttttttgt gagggtctct accatcggaa
    59941 taaataatgt atacctgttt gttttttcta aaagttcttc tcttcgaaga atggtcaaaa
    60001 cgagataccg agaaaatcgt atgaagtcct ctcctgaaac aatataatta tatgatataa
    60061 gaacctcttt taatgtcttt tggacagtcg gcatgatatt ggaaaaaatt gtactgattt
    60121 gttgaggaaa ccttgcgtgt tggatcaccg tttctgttcc aacaagagat aagaaaattc
    60181 tttttgaatt ttcttcagca atgattttta gtccttttgt cgacgaaact tccagttcta
    60241 atttaggatt gcgctcgatc caacgcaaaa tcgtttttat ttgtaatgat acggctgttt
    60301 ttgaaagaaa gaaaatgtct gctatctttt gcatactgac ataccctttt tgaaacaata
    60361 agtacgtcac aatagttgaa gctcggaaat ccatgctgga atagatttta tgtttcgtca
    60421 cctcttgtat gatttgctgt ttagtttcag attcaattga ttctaaaaaa taacctgaac
    60481 gtttatttga ctggataatg attttcttct cgtagatagc aagcatattt ttgatttcag
    60541 tttggatcgt tttcttgttg gtacctaaag cttcagctaa ttcttcgctt gttatccaat
    60601 gattcttatt tcttaatact acaagaattt ggagttgtcg tttatttaag tccatttgct
    60661 tacacctcct ctttgttata aacatacagg aaaaacctct caaatgacaa tagtcacttg
    60721 cagaggttta aaaatcattt gaagaaagat ctatattcaa ggtttttacc attagactgg
    60781 ataatttgtt tataatattc aaaactatct tttttcaatc tcctaaagct tccgctccca
    60841 tcattttgtc tatccacata aataaagcca tatcgcttcc tcatttcccc tgttcctgcc
    60901 gatacgatat cgattggtcc ccaccataag taaccaatga tttggcaacc atcttttatt
    60961 gcctcagcaa tttcctgaag atgtattttt agatactcac aacgttttgg atcgtggatt
    61021 cgattcaatt catctggtgc ttcatctagt ccaatgccat tttcaactat gaataatggt
    61081 aattcataac ggtctgtcaa ttcattcatg acataacgaa accctagagg atcaattggc
    61141 caactccaag gttcgggaga tttttccttc aaaaagggat tatcgaaacc atttgctccg
    61201 ccagtatcta cgcgcatttc tgcttctttt ttatagacag cgctacgata ataactaaat
    61261 gcaatataat ctgccgtgtt agcttgcaag cactgttcgt ctccatctaa cattactggt
    61321 gcacagtctt cttccttcca tgtcctgtaa atataagctg gataatgccc tcggcacatg
    61381 acatcggaga aaaaccatga attgcgttta aattgcagtg aaccaaatac attctctgga
    61441 tcacagtcat atgcataagt cgctaatgca gaaaagctac acataatacc catcttagca
    61501 tttggatcga ttttctttaa taattgagta gcacgggcgt tcgctagaaa catatgatga
    61561 caggcttgat aaatcacttt ttttgttagt gtagcaatgg gttcaagttt atctctagca
    61621 gggaatgtaa ccaatccagc agctgcataa ggcatacgaa aagcattatt gatctcatta
    61681 aaggtcatcc aatatttcac tttcccttgg tagcgttcaa agacggtctg cgcataaaat
    61741 tcaaaaaagt cgattaattt tcgattttgc caccccccat actctcctac caatgctaag
    61801 ggggtttcat aatgactaag agtaattact ggctcgatat catatcgatt taatgtattg
    61861 attagtctgt cataaaatac gagaccagcc tcatttggct tctgttcgtc tcctcttgga
    61921 aatattcgtg cccatgagat gcttgttcga aaagctttta aacctaactc cttcagtaaa
    61981 cgaatatcct cttcaaatcg atgataaaaa tcaatcgctt catgagaaag ataatggagt
    62041 gattcgtcta aagcaatctc ccaaatcttt ttttcttcat tccactgaat actaggatgc
    62101 tggttcatga tcccgataag cgtatctgtc acattaggta atttgccgtc ttccaaccat
    62161 gcaccttcac attgattagc agctactgct ccgccccata aaaaattttc tggaaatatt
    62221 tcctgatcca taactatctc tcctcgctat caacaatttc ttacttgaag tatagctcga
    62281 ttcatcaaaa caagatattc taactatttc ggcagaagag aagaaaaaaa ttgaatgcta
    62341 ctcttcattt ttaatattta tatataacaa atacataaga cgatccccga aagaaaacac
    62401 tcgttaacca tctaagcaaa cgatttattt tacttccaac acaaatgctt cataaggtcg
    62461 taaatcaact ttgccgtctg gtaactgttt cagaggataa tttgacacaa taacccttaa
    62521 agcttcacgt ggaatagtga acgtctgctt ttcactggac atattacaaa taacgagcca
    62581 ttgctggtct tcatatatgc gagaataggc aaagacatgc tcaggcgtct tttccactaa
    62641 ttcatagtct ccccagacga tgatgtcatg ttttctacgc aaatcgatca atttcttgta
    62701 catataaaaa acagaatctt gatctgctaa cgcttcttct gcattgattt ctttataatt
    62761 tggattgact cgaagccatg gaattccagt agtaaaccca gcatgttcac gggcgttcca
    62821 ttgcataggc gtcctagcat tgtctcttcc tttcgccttg attgattcca agatttcctc
    62881 ttttgtaaat ccagaagaaa tcctttcgtt atacatattg attgtctcaa tatcttttgc
    62941 ttccgcgata tcatcgattg ggcaattcgt catgcctaac tcttctcctt gatagatata
    63001 aggggtgcct ttcatcatat ggagcaagat agcaaacatc ttggcacttt cttttcgata
    63061 cacatcgtca tttccccaac gagaaacaat tcgcggaaga tcgtgattat tccaaaataa
    63121 actattccat ccttcatcac ctaaagatgt ttgccatttg gataatactt ttttcagttc
    63181 agagatactc aagggtttca aatcccattt gtctttgcct tcttgctgat ctaatcctat
    63241 gtgttcgaat tggaagacca tggataattc atttctttta ggattggaat aaagtttagc
    63301 gatttcggta gttgctcccc atgtttcgcc aacagtcatc agatttttgt caccaaaagt
    63361 tgcttgattc atttcctgaa gatactcatg cagtttaggt ccattacttg tgatttcttt
    63421 atccggttct ttgccaatca tatcgatcac gtccatacga aagcccccaa tacctttatc
    63481 gatccagaaa ttcatcattt gataaatctc ttggcgaacc tgtttatttt tccaattcaa
    63541 atcaggttga cgcttgctat acaagtgcag aaaatattgc cccgtttttt catccaactg
    63601 ccaagcagaa ccactgaata ttgagcgcaa tctattaggc tcttttccat tgaccggatc
    63661 acgccaaata taatagtccc gataaggatt ttctttattt ttacgggcct caatgaacca
    63721 cggatgttca tcagaagtat gattcaccac cagatccatg atgatacgga tatttctttt
    63781 ctttgcttct tcaatcagtt cttccatttc ttccatcgta ccgaattctg ccatgattgc
    63841 ttgataatta ctgatatcat acccattgtc atcattcgga gactcgtata ctggagaaag
    63901 ccaaattgca tcaataccta aatacgccag ataatccaac ctggaaataa tcccccgcaa
    63961 atctccaata ccatcttgat ttgaatcttg aaaacttctt ggatagattt gataaacaac
    64021 tgaatggtgc caccattttt gttccatgat tttcctccta taaatggatg tttctatttt
    64081 ttgcttaatc atttatttta gtctctctca ctaaaaattg taacgctttc aaatagctat
    64141 tgcaccttgt tatcggtaac agaataaaac aaaaaaacag ctgaggaaat tccctcaact
    64201 gttttttgaa aggattgatt tatgcaggga agaatgctga tttcacaact tctttataaa
    64261 cggtgttcac tcagctgtcc cttggtatta gctcaaaaaa cggcaaaata taagaaacta
    64321 ttttttcgtt tttttctcta atactcaggc cagaacgctg atttcacaac ctctttattt
    64381 cacattcaat atccacatga atcccacaaa tacaaagaac agaccataca tgattggaga
    64441 tacttctttt cctcttttag ctgctaacat ggtaattgga tagaagataa aacctaatgc
    64501 aatcccatct gaaatactat aagtcaaagg catgccgatc aagatcaaga atgaagggat
    64561 cgcaatctct aagtttcccc attcgatttg tcgcaaagat tgtgccatca atactcctac
    64621 cataatcaat gctggtgcag ttacttgtga agtaacaact gatagtaatg gagaaaagaa
    64681 caagcctaac aagaagaaaa tccctgtagt aatagctgtg atacctgaac gtcctccaac
    64741 ggcgatacca gctgatgatt ctacaaatgc accaacagga gaagtaccaa ataaggaacc
    64801 cgcaagcata gctgttgaat cagaagctaa agctttccct acacgaggca tcttgttgtc
    64861 tttcatgaaa cctgcttggt ttgctaatcc aactaaagtt cctgctgtat caaagaaagt
    64921 cacaagcaag aatgtcagca ctacgaccca catttgaaga gaattgatgt cccctacatg
    64981 ttttaatgca actaaaaatg ttggtttcaa acttggtgct gcggcaacaa tttcagaagg
    65041 cattggaatc aaacctgtga ccagacctaa aatcgttgta gctgccatcc cgatgaagat
    65101 gccacctggt acacgccgaa caagcaagat agcagttacg actaatccaa aaatcgtcaa
    65161 ccaagtagaa ccaacgttga gtgatcctaa tcctactaat gtagattcat tcgaaacgat
    65221 gatcccacct tcgctcagac caaggaaagc gataaataga ccgataccgc cagaaatcgc
    65281 atatttcaaa tctgctggga tcgcatcaat gatcatttcc cgcagcttga agattgtgat
    65341 caaaataaaa atcaaagaag caacgaatac gccggctaat gctgtttccc atggaatccc
    65401 cattcctaaa caaacagaat aagcaaaaaa agcattgatc ccaagagcag gtgccgttcc
    65461 aattggataa cgggctaata cccccattaa aacacagccg atcgcactgg ctaatgcagt
    65521 cgcagtaaac actgctcctt catccattcc agaagcacct aatacagttg gatttacaaa
    65581 taagatataa gccattgaga taaatgttgt aaatcctgcc agtacctcac gttttaccgt
    65641 ggtgttcaat ttttctattt cgaagtagga aagtattttt tccttcatct tccatccccc
    65701 taaatccgaa cattataaat aaagtccgtt aaaatttcga tttattaata aaacaacgtg
    65761 ttttatcata tactaaaaca aaacataagt aaacaaaaaa ttcggatttt aagcaaaatc
    65821 cgaacgttcc atctgattaa atccctttat ctcaaagttc atgaacattc actttggatt
    65881 acaagaattt ctttattgtg ttaataaagt ttcttcattc tagtctcaaa aatcaatagt
    65941 gtgatttgat tttaccattt cgtttctgtt cttctttgat gaattctttt gtatcgacag
    66001 gattcagatt atttagtccg ccaaaacctg tatcgaccat ttttccccag ccttttgtct
    66061 tcttttttcc tgatttgaga ttctttgctc gaagcttctc actatgtttt gctcgccgat
    66121 acttcaaata accttctaat cttcccatta gatccactgt ttttcctcct ttttattcaa
    66181 tcagacgact cagcttttcc tataacaaaa taattgcctt cagggtcaga aaaattgaaa
    66241 gtcaagatgc cattgttatc tgtgatttct cctggttctt ccatgttctc gtagatagtt
    66301 tcaaattcat ccgtaaaaaa tactaaagaa ggcggtggtc ctaatacctc tggtgaaaac
    66361 ttctgcacaa atacttttgg gaatacgcct aattctaatt cttttgagat gctgagtaca
    66421 atactcttaa attcttctgg caattcgatt gtttcagaaa tttctgcacc aattttttct
    66481 acaaagaatc ggcaaatcat ctctacgtca ttgacataaa gcatcacacg tgttttttgt
    66541 atcatcattt gacccttctt tctatttgat tttctttcct gtctataaac tgattccatt
    66601 atatcacgaa agcgcaaaca ccttgtgttt gatactattc aagaaaaata aagcaatagt
    66661 ttctaggatt gctttcctcc acaaactttt tttacaaaaa aaaaacggca atgaatgccg
    66721 ctcttcttat ttcgattctt ttataattct gcttctgatt catctttggt tagtgtgtgt
    66781 ctaacactag ttacgccaaa tgtttgatcg attttttcct tcaacgcttc gattgcctgt
    66841 gcgccacgtg ccgcttgttc agcattgatg gattcaatga ccagcaccgc tgcttgtgtt
    66901 tcttccgtca gcatcgttct ttgggcttca cgccagttga gacagcgaca gatcgctcct
    66961 tgttcatcat agtagatgat ttcttccgga agtgccggag catcggaatc tgcacctaaa
    67021 ggcaggaatg attcgccacc ttgggctttt cctaaatgca gatttcctgc gatcttttcg
    67081 atatcttctc cgccgcaagg tacgccaaaa gacaaggaaa tactattata gatatctaca
    67141 agcggattga ttgggaaaaa ttcccgttct tgatttgcac gtttcagtaa agcttcaata
    67201 gaagaacgtg cacctttttt agtcttgaat gtggtaaatg cctgacgcca ctgagcaatg
    67261 acttcgtttt ggctgaatgt ttcttctgta aggtaatttc ttgcttcttt tgctgcctca
    67321 ttcaataatt gatgatacgt ttcttcactt tcttttgtta cgtggttatc gataccattt
    67381 acggataaga tttcgatggt tgcttcagga aatacttccc agaaattggt atccactatt
    67441 acttttttca tctgttcaca cctcttgatt agaataattg cttgatgaat agatagtctg
    67501 tttggggatc atctcccata taaaaaacat gttcgctgta tttgataaat ccttttttac
    67561 gataaaaagc gagcgcaaca tcgttgtgtt cccaaacacc gagccaaatg gctgtttttt
    67621 gcttttcttt tgctttttca atagctgtat ctagtaaaaa tgtaccgata ccttgatgtt
    67681 taaatttttt tcgtacatag attcgctcga tttctaaaaa atgatcagcc atttcctcag
    67741 attgactcgt tcctgtattt agtttcaggt aacccgcagg ctcttgatcg atactcacta
    67801 ggaaaaaatc ggtttcttta tcttttagct cttctgtaag tttttctagt gcataagctt
    67861 gtgtcaagta atcagctaaa tgctccggtg aattatcttt tccaaatgta tctgtaaatg
    67921 tttcgatact aatttgttgt agtaagtcta catctgaagg cgtcattttt cgaatttcgt
    67981 atttattcac ggcttcttcc tttcaataga tccttttatt gccttttttg acaaaattcc
    68041 aatcttcgct aacattcttg catactttat ttaaaagata ttccaattgt tttgcttctt
    68101 cgtcagaaag accatttaat gcgactgcat tggagtagtt gttttctcga atgatgaaag
    68161 gatagatttc tgctcctttt ttagtcggat agagtttctt gattttttta ttttctttat
    68221 cttccaaacg ttcgatcatc ccattggatt ctaatttctt gattgctcgg gcagtcgttg
    68281 tacgatctac tttgatcatt tctgctagtt tttcttggat gattccagga ttttcgcaaa
    68341 tacgtactaa ataaagatac tgtcctcttg ttaaatcgac ttctttgaat tcgatattgc
    68401 taatagaatc tagcgctcgg gcaatcattc cgatgtctcg aaggatttca gccatttcat
    68461 cccaccttta ttttgtttgt aagactagtt cacctctttt tgttgcaaat gcaactattt
    68521 tcaataaaaa aatcaagttc ttttttaata actagtaaag tatattcttt tcttctttta
    68581 cgaaaaagct caatcacaat agatctggtt tttgttttct aaaataagta actgtttctt
    68641 cgttgttcgc ttttctgata gctttggcaa ctcttctata ctaaaaaatc ccatgttgga
    68701 agtttcatta ttctcaataa acttggcctc ttcaccgtgg atcgcacaag caaaaacaag
    68761 tttataatac tgaaaaagct gtggaatatc tttttgttta ttcgtatcaa aaactgctcg
    68821 caactgagta gtttctactg ttaatcctgt ttcttcatag acttctttac gcacattttc
    68881 ttcaggagac aatcctattt cagcaaatcc accaggaagt gaccattctt tcgtccgttt
    68941 atcttcgatt agtaggacct tgccatcttt tttgatatag gcacgaacat ctacttttgg
    69001 tgttggatgt ccttctccaa tcgttgtgag cgcttttatt tcttcgaaag tttcttttcc
    69061 tatttcactg atcagttcca atgaaatcgt ccggatctcc tcaaaacgct ctttatcaaa
    69121 tacatctttt ccataatata gaccagcttg agaaagtgcg agtagtcttt tgtattgagc
    69181 caacttcttg ttcattctct tcccttcttt tttagcaaat gtatgactat gtaatcaagt
    69241 atagaagact ggtttaatta cggcaaataa atataatgaa atctgcaata aataaaagaa
    69301 tgttaaaaaa ctcgagaaca aaagacattc gacttctctg gggctgtgaa taaatggcgt
    69361 tcaaaagctt gcatctgcgg taataagccc caccaaacga aaaatatgac gagctattct
    69421 tgtctggctg ttcttattaa ttgaggcagg acagcttttt cacaacctcc ccactaaacg
    69481 gtgttctcct accaactcct cggtcacaag tcacaatatt catcaaacat gagaagctgt
    69541 ttttttgaaa ttgctccttg tgactcggag ctgaacgaca ggctcacgac ctctcggtaa
    69601 acagcgttca aaagccaatt tttcgatatt aagccatttc tttgttactt attgtcattg
    69661 atttcttttt ctaatttatc caatagtgga gtgtaatcca cttgagtata gtctgttaca
    69721 tcaaattcat atagtgttcc taactggaat ttgtcatatt ttcggtcggc gatgatcttt
    69781 ttgaatgctt ctttcgtaat atgattggtc cctttcgttc gatcttccaa tacgtcacca
    69841 tagtgataat gatccatgat atagctcaaa tgacgatctg attcacgatc acgtttgtac
    69901 cgacgttgcc ataacacttc aaagtctgct gttaggcgaa tcgtgatcac ctgatatccg
    69961 tatctatctg ctaattcttg gagtcgtgct ttttgcttat cactaaaagg atactcggac
    70021 acaatcactt tctttcctgc ttccatatac aaatcaagtg ctttgtaata gaaaggataa
    70081 actttcgtcc tttcttgttc cgcccgttct tccaaattgt taaacccgat ggattctgca
    70141 tagtattcct tgatttcatc gagcgtgatg gcatacatat ctggaaatcg ttcccgtagt
    70201 ttattcataa gatatgtttt tcctgtacca ggactaccag ccagaagaat gaaatacttt
    70261 ttcatctcat ttatttccta agttaattgg actttccaag ttcataaaca gtccaatctt
    70321 atgcttgaca atttctttta ctgcttcatt tgctggaatc acattatggc gaagagactt
    70381 gttgatttct gtttcactaa aggtttcttt agctactttc gtccagttga ctaaaagctc
    70441 cgttccaaca ttgaatttgc ggatcccgtt attgatcaat tcaggataat cttcttcttt
    70501 cacacctgtt cctccatgga taactagggg gacatcaact actgcatcga tttctttcag
    70561 caagggaatg tttacttctg tttttgattt gaattgtcca tgattcgtac cgatagcaat
    70621 agctaatgca tccacgcctg tagcttctac aaatttcact gcgtcttccg gtcttgtata
    70681 taccttgtca ttttcagcga catggattcc ttcttctgta ccgccgattg ttccaagttc
    70741 tccttctacg gaaacaccgt gcgcatgggc atattctact actgcttttg tcttcaggat
    70801 attttctttg aaaggcagat gggacccatc atacatgaca gaagtatatc cgctgtcgat
    70861 tgcttctttg atatcatcaa agtctcgggc gtggtctaag tgcaagactg catcaaccat
    70921 ttcttcttct gcaatagctg tcattacatt gactaacaca tgcatgccga tatatttagc
    70981 ggtatcgaca cttgtttgaa taatgatcgg cgaacccatt tcttttgctg cgcctagcat
    71041 agcaggaagc atttctaggt tatgcgtatt aaaagctcca actgtaaagt tcaactcttc
    71101 tgctgttttt gttacttctt tcaatgttgt atacatcttt tattgccacc ttatcttttt
    71161 atttgtttcc tttgatcgtt acttgttttg caatttgtcg catctcatcc attttgccca
    71221 tgtagtaatc gatcccttga tcatcaccag cacgagcagc atctgcacgc ttctggttat
    71281 agaggctcat cagtttttta tacccatctc cgatcgtctg tttattttcc aaactctttt
    71341 ctaaatattg gatggcttga tcgttcacat acaattcaga aaatttaagt ccaacttgtt
    71401 cataaagttt cgctaattta tgcttatctt gggtagtgga aatctcttgt ttcaattgtg
    71461 taatctctga ttgaatcttt tcggtcgctt ctggcgatag ggctttttct tcttttgcca
    71521 gaactttttt cggttctttt tcttttttct taaaaaatcc aaacatcatt ttccctactt
    71581 tcaattaaaa tgctttcaaa actgggctta agatccaggc atataagagt gctgcggcta
    71641 ctgtatctac atcggttgct gtagcattgt tgaatcccat cgaattaaag atcgttacta
    71701 gcaaagcggg caataatgta ataaagaaac catgagcaat accgccaatg atcgctcctc
    71761 ggcgtccgcc aactgcgttg ccaaatatcc ctgctgtccc tccggcaaag aaattggtta
    71821 gcataccagg taaaatcatc gctaagccga acatgggcaa agtaaacatg gcaataatcg
    71881 taccaatcgt tgtcgtaatg aaacctaaaa tgacagcatt tgggctataa ggaaagaaaa
    71941 ctggacaatc taaggcaggg atcgcatcag gaactaattt catagctatc cctcgaaatg
    72001 ccggcacgat ttcacctaac agtagacgta caccagctag caatacatac acacccacta
    72061 cgaattggat ggcttgtaaa aaggcaaaca tgatatagtt ttgatctcct gataattcag
    72121 aagcgaatgg ttcgcctgca aataaaacag tgatgatata tagcgggacc atcacgacca
    72181 tgacagacaa ataagtatct tgcagaaatt cgaaatgtgt cggcaacttg atatcttcga
    72241 tcgacttttt attttcgcct ttctcaccaa aaagcttagc aacaccggct tcaaataagt
    72301 acccgatcgt acaaaaatga cctaaagcaa tatcatttga tccagtgatt ttacgaatga
    72361 tcggttgcgc tactgccggc atagcaatgg cgaaacaagc tccgataaaa ccaccgacca
    72421 agatcaatac gatccctcgc agaccggcaa aatagccaaa gactgtcgtc atcgttgcca
    72481 tccataaaat tgcttgacca gttaaaaaaa tgtacttcca ttttgtgaaa cgagccaaaa
    72541 taatattgaa tacaaaaatg gctaagaacg tcagtgcaat atctctacct aaacccaaat
    72601 cattcattgc ttgaccattg atagattcaa tagaagggat gatcccttgc atatgaaatc
    72661 cttcagtaaa gattttcccg aaataagtta aacttccaac gatgatgctc gaaccggcac
    72721 tcaacacttg aaatcctagg agtgtcttta acgtgccaga gatgacttgt cctgctgatt
    72781 tcttctgcag tagtagaccc aacatagcaa tcaatgcaat ggtgatcgat gcctgagtca
    72841 aaatattttc gatgataaaa ttgataacgc ccatgttttt accctctttt ctttttgtat
    72901 ttagataact cccttatctt gcagaactgg ggtgattttt tcttcaattt cattttttga
    72961 aacaatattt ttcaaataga tcatcgccgt tttaggatca actgcgaact tttcgaactg
    73021 cgaacgaaaa ttttctgctg tgatgatcac atctggtttc atggaaactg cggaagaaat
    73081 atcacaatgg tccagtttgg cttctactcc taatttgttc aaaacatcct cagcagacat
    73141 ctgtgctgca aaactacttc ctaaacctgc accgcatacg aataaaatgt tcaatttgtt
    73201 catctttgtt ctcccccgta tcatttatta tttctcaact actgaaaaaa gcagttgttt
    73261 gaaatcttcg atatttgtgc attcaatcaa tcgatccaac ttctcttcgt tgttgatcaa
    73321 ttcaattagt tctttcatga tgttcagatg cgagtaggag tctactgctg ccaaacaaaa
    73381 aataatcttt actggatcca tttcaggatt accgaaatcg attggttgct caatcgtagc
    73441 tacgctgact cctaatttat tgaccccatc ttctggtcgg gcatgggcta gtgccatgtg
    73501 tttgccaatc acgatatacg gtccgtaatc attcactgca cgaatcatcg cttcgacata
    73561 gcgctcttcg acaatgtttt ctttaaccaa tggtctagca gctagttcaa tcgattcctc
    73621 ccaagtagtg gctttttctt tgatcatgat attgctgtcc gtcaaaatat cttttaacat
    73681 aggctggatc tcccttttgt tgatttctaa attgtttgtt tcgaataatt tttctaactt
    73741 gccatagatg attcgatcta ctcggccacc actttctttc atgacatcta ttatttgagt
    73801 gaataactcc gtcgattcat gactgttagg ctctaaccgc tgtagttctt catttctttt
    73861 caaaaagtct tctataacca agatattcgt ctcagttaaa atcggatcga caactaaaag
    73921 cggcttattt cgataattca attgaaaggt gctgaaaacc agattgacat ccaatttatc
    73981 tactaattcg atttcttttg aacttaaaac tgcagtaatc tcgatctgag gaaacttttc
    74041 tttcagattc tctgctaaca gatttccagt agccatccca tggttacaga caacgactga
    74101 tttataaaca taattcaagt ctcgcttgat tacactggcg atcgtcgaaa agtggatgac
    74161 aagaaaagct atctcgtcct ccagtatctt gccaccaatt acttcttcga tcgtaggaac
    74221 aaaatgagtg actgcgcggt agattgggaa ataatttgtt cggatgtttt ctttcaatgg
    74281 attcatgact tggatatgat tcttgattct tacaatcagt gcagccatgt gcttatagag
    74341 attttcgaat aaagcttctt cctttagatg gaaaggtacg tgtgtctcgt tctctacaaa
    74401 ttggatcaat tggatcgtta gtaattgagc ttgtacccac tcgattgaat tggagatatc
    74461 tctagcattg aacgtctcaa tagtgaaacg aagataattt ctttctactt gcgggacatt
    74521 gtccaattga aattcctcga tcatgtggtc aataaatgca gaaaagctac tgtcttttat
    74581 ttctgtattt ttccaattaa tggcagagat aaattcatgt ttcctgattc gctggatcca
    74641 gatcaatgta aaaagcagga tttgtttttt ataaatatca tcttcttgtt tcaacaactt
    74701 attggaatag atctcctgta tttttttgat ttccaccaaa ggaaaataat ggagaaagat
    74761 tttttgagcc ggtgttaatt gtgcatcttg attcataaag aagtcggtca ttcccagatt
    74821 ctgattgata aaatcataga tcatcgtacg gatagatcgt tctgaacctt tataaaccag
    74881 tccttgcttt ccataactga cgatctctat cccataactg accagtgttg ctcgtaaccg
    74941 tctcatatct tcatctaatg tacttttaga gatttgaaat tcttcttctt ttttgtttag
    75001 atggatcggg attcggctgt aagcaacggc taaaactaga tcaaaaatac gttcgcgccg
    75061 attcaaaaag ccgtctttca catcttttat ttcagtttct aatcgagctt gcttttcctt
    75121 ttccagcttc aacaaaaaac ctttgttgcg aattgtacgg atctccggaa gctttttact
    75181 gctcaaccag atattcgctt caagaacttc ctgacggatc gtccgctgac tgacattgaa
    75241 ctcacttgct agatgttttg cttttactgg atattgggct gtcatgattc tgtgaagtat
    75301 ttcaattgtt cttgttttca tagaaatgat ctccttctga tttcaagtat atggttccgc
    75361 ttacataata aaaagtagat atttctgcca cttgaagtgg aaagaaagta agcaaagcaa
    75421 acaaaaaata agccatatgc tttttcatct cctcaacgaa aaagacatac gcctattatt
    75481 acaaaaattt tgcccatcta tacaaaaaag aggttgtgaa aaagctgtcc tgcatcaagt
    75541 aataagaaca actaaactaa aatagtgctt cctatttttc gtttggttgt tcttattatc
    75601 gcagatgcaa gcttttaaac accatttagt ggagaggttg tgacagagat gttcagcctt
    75661 gagcgataag aagcgatttt gaaaaatcgc ttcccatatt ttacaaaatc gtgccttatt
    75721 gccgataggc tatctctggc acaccgttta ttcagaaaaa ggagctgcga caaggctttt
    75781 gtcacaactc cgttcataaa tatttcctgt caatccagca taatcggctg aataaaatcg
    75841 gcttgccatc ttttttcttt ctcagaaaaa tcaaaatacc atatctgaga aaaatactgt
    75901 cgttgtgtct tacttcctga gatcaatcgc ccatcttttc gatcgactga ataatcacag
    75961 catctgaaat caattcggat ggcaaaacta ttttcgtgga tctgtcgata atttcctact
    76021 tcctgaatag ttattttttt agtatgattt cttacaccgt ctgctttgtt tttttgcaga
    76081 actttctgat gttcggcaaa cagcttgtct gtataacagc ttctggcttt ttcaggagtt
    76141 tcttcttccc aagcggattg gatcttcatg aatatctttt ggatttccag aaactgtgct
    76201 ttcttttctt tagccgttcc tgacatgcgg gacaatatct ccgctttcag ccttttcttt
    76261 tgtcttttat tcttgacgat agaaaaagca gaaacccctc ctactgacaa aacagctaat
    76321 gcaagaaatc ccgtttgctc ataactagaa ggacctgtac ctggaccata atacccataa
    76381 gaatctctgc cgtaagaacg actgccaaaa taactgcccc catatgaacg accaccaaat
    76441 gaacctctgc ccgaacttcg accgctagat gtacctccac catgaccacc cgcgacagcg
    76501 aatccttggg tcggcagagc aaacaaacat aggcccacta acaaaatgat tgctaaataa
    76561 ttgatttttt tcattgtctt cctcgttatc ttttattaca aaaaactatt tttatgatag
    76621 ccttgctaaa aggaagagtc aataaccaga tgcataaact gtttttttag caattttgtc
    76681 ttatttagtc attgagtaac atcggacaaa tgtatgtgtc ggcagtccat aattcctcta
    76741 tcttcagcat gaacaagctt gcagacaaga gatctgcgct tcctccagga gagatttggt
    76801 tttcctgaca aaagtgcaac agtgctgtaa atggacgatt tggtaaagca ctttgactag
    76861 cagcatgagc aagtttttgc atttccacta acgttttctg atcactgcga tgcaatacgc
    76921 atgtgtcatc tagcgaactc atcaaaacta acaacatatg catttgtttc tgtacatatg
    76981 aatcattatc tagctcctta gctgcttgaa ttgcaagcct gatatgcgga taccctaata
    77041 tcgcttcttc atatgcacca tttacgccat atttttgctt caccctatga ccatgagtgg
    77101 tttttttatg acgatatttt gtatcaggaa aagcagcaag cttgctgaca tcatcaagta
    77161 ttttcgataa agaaaaaggc tgttccatac tgattttttg tgcaatgaca ctgatcaata
    77221 gccccattgc ccaaatcgct cctttatggg tattgatgcc atttgtagca atcagcattg
    77281 ccttttccgc ttttcgccca atctcagcaa ttctttctct taactcctga tcaatagcat
    77341 gatgccatgc tatttgagcc atttcttcaa aaaaaggagt tagcgtctta gcagacttaa
    77401 gaaataaagc atagtccata tcggaatgtg cacccgcatc cagtgcatcc actaatccag
    77461 gttttggact taatgttact tctgcgatca atgcttcctc taccaacgca gcgagttgct
    77521 gagtcactgc tttttttcgt tcgtcattta tcatgacact cactccttct tcctactatt
    77581 acttgctgaa accttttttg atagctaccc aaatgatatg aagtaaccag cttaaagcaa
    77641 atgcacaact tgccgtcatt agataagcta caagaatcat gactcctgaa ggtaactgca
    77701 gccaactatc tttaaacaat aataacagta cttggaaaac aaatacattg gctaaatacg
    77761 tacgataagc ataaacagac aaccatttga acaatggcaa ttttggcgaa tcgtttacaa
    77821 tcattttgga agcgcctatg aagacagcaa agatgatgac taaactgtat aaactttgga
    77881 tcgtattcaa gtaaggtgca ttcgcaaagc tcaagtctcc tggatgtgcg agcaatgaac
    77941 ggacagaaaa gaacgcgata actaaggcaa caggtaagaa aagataacgt actctgtcca
    78001 aatattgata gactttttcg tgataaacaa atgcggctac cccataaatc atgaaactag
    78061 caacaaaccg atctaataag taccagctgt catgataagg cccagtcaat acttgtgttt
    78121 gatagaacag ataccatgcg acatataaaa tcgttgaacc aatcaatact ggccatacat
    78181 attttttatt agcaaatact ttgtaaccga gccaaacaaa aaacggcatg aacaattgga
    78241 tctgcagcat cataacggta taccataaat gaggcgctcc atcacctgtg acatatttca
    78301 gtaaaaagct tgcagtatcc gtatacggag tttgttgttg gactgctgga aatagccaaa
    78361 gataagccgt cgtccataga agatacggaa cgactagttc aaaaaacttt tctttcaaaa
    78421 attcccaata agacaaatgc tgacttgttt ttaccatatt ataaacaatt gcaaaaataa
    78481 acattggtgc tgtgtattta acgatgacgt aaaaggtacc aagaaaagct gtatttgttg
    78541 cgctgtggct gtttgccaaa gcaaagctca atatcgtttg catcataaca gccgttacag
    78601 ctgatacttt ctggaagtca cttacgttga ttttgatttt tttgttttca aacatctctt
    78661 tctctctctt tttctttatt accaaagttc tttggttaat ttaggtcctt cgactgtttt
    78721 caatagaatt tttttctctg gctctctcaa atactctttt agtgaaaaac cgccttgccg
    78781 agtcactact tgggtatcga attgctcaaa aaaagcagga tgcgattgaa ttacctgaat
    78841 tggcaattca atcggtgaat ttgcgtacag cagcaaatca aaatcactgg tttcttttac
    78901 tgccggaatc ccagtcgata attcaaatcc taagctgccg ccgattcccc atttacatcc
    78961 tgataatatg tttctagcag catgaaattg ctgataaaca ggataatcca tgattttctc
    79021 ttgtctatac gattcttgtt cgatgatgtc ccacggatga atgacttgtt tgacggcatg
    79081 ttttgagatt tctgttgacc atctctgatt gcgggcaggt ccacgtaaac caatcggtag
    79141 tatttctgcg tgatccgtcg acgcacgacg aactgttccg aacatctttt cagttagaac
    79201 gacccattca ggcaaggtga acccttctat ttcatgttta tcaaaaagga caatatcatg
    79261 tgcttgaatc attttttatg catcccattc ttcgtccatt ttggcacgga ctttatttgt
    79321 ttcgacacgt ccgaatgttt tggctgtttc gtttgtgtat cgatttgtca gcatcgtgtc
    79381 atttgtattg cggacatctt gaatggcttc attgattgct tcgatgactt tgctgacatt
    79441 ttgttctgaa gcagcttggt cggtgatatc ttctaggaaa tgatagatcg ctcctagttt
    79501 tgtataatta ttgatatcgt aagcgatagc tggaactttt tcagcagctg cttcgatttc
    79561 agcaaccgaa cgttttgtca cacgtgcagc actttcttta gacatcgctt ggacggtaat
    79621 ttctttattg tttaaagcaa tcaagcggct tgattgtaat ccatgtgcta aaaatgcacc
    79681 tgaaatagca tttcctgcaa tcaatccaat aactggatgt ccagcttgac ggagttttgc
    79741 ataagcagca gcactattag ccaaagccac atggataccg atcaattctt cgttatagcc
    79801 gtatgcttgg cttggtacat cgatcacaac gatgattggc cgtttcactt ttttgtcttt
    79861 atcttcttcg taaacgtgat ccaaaatttg tcccatgcgg aaaccttcaa ctaaaccaac
    79921 ttcaccgttt cgtacacggt acatcgggtt tttaggatca ggtacgattg atgtcacgat
    79981 ggcttcttct atgaatttac ttgatttacc ataatacaca gtactaatag aagaagttgg
    80041 atttttcatg ccagttagtg ccgcaaacca atcgtaacca acacttgctg cagctggttc
    80101 atttccttct gctacttctg gtaagtcaat tgattttgct tgatggttag caattgcttc
    80161 attgtaatcg tcaatggcca ttggttttga aagatctaaa gaatcaagta atgataaata
    80221 aaatgctgag ctttcactgc gatgcgtgtc ttttcgttcg tccattgctg cgatgacagc
    80281 agctttgatt gcttctacac tatcagtcac taattcatca atgatttttg attctacccg
    80341 ttgacgagat cctaatgtat tccaaatcaa gtctttgtca ctagaatcaa attctcgaac
    80401 gcctgcttct tgttcaataa cttctggtcc attcaaaccg actctcgctt tttttgttgc
    80461 gattaaataa ctcattaatg ctgaagtaat cgacataccg ccaaatgatc ctacacgtcc
    80521 tggaatcaaa ccgatgactg gtacatattg ttttagagca atgattacat ttccgatttc
    80581 tgaaatagat aacagtccgt agtttgcttc ttgcaaacga acaccacctg tatctagtac
    80641 aatgactgga aagatctcat ttcctttttt attttcttct aacacatgtt caagtgcagc
    80701 aacgattttt gcaccggaaa cttcaccgat accgccacct tggaattttc cttccatagc
    80761 gattactact gcttgtttgc cattgatcgt gccacggctg acaacgatcc cgtcatcact
    80821 ttcagggacg attccttgtg ctggtaaact tggcgcgatg atttgatcga atggatcaat
    80881 caattcacgt ccattgtcaa gtagagcgtt cactcgttct ctggcgttta attctacaaa
    80941 actatttttc atctgaaagt tcctccattg cttgcgtcaa tcgtaggtac acaactcctg
    81001 gtgtagcacc gaagtcattg atcacgatat ctgctgaaat tggataacga tcaaaaaatc
    81061 tcgttaatac attgttccat acttcgccga agccatcgct tcctgtacaa atttttacag
    81121 tagattctgt tttttctgtt ggaaacatca agatttccaa atctcctgaa ccgaccactc
    81181 ctacatggat tttcttattg atcggctgtt tcgttggata tttataagct aattgttcca
    81241 tggatctctc ccctttttgt aaaacagagc atacacgttc tgcttattcg tctttcttct
    81301 tccatctggg taaatggcga caaaaggttt ttctcgccaa ttttatgacc aagttctgaa
    81361 tttcattggt ggttcataca ggccatctga ccattcgatc aaatcatcga tggtttgtgc
    81421 agctaataat gaacgtttcg cttcactacg tttgatgcct agatcttctg gtaatttcac
    81481 gatgccggct gcacgcaagc tatctagtga ttctttcgtg ctagtcattc caagaggtgt
    81541 aacaccgcca attgctgcaa ttgctgcttg tcgttcttct tttgtttttg ctttgtacaa
    81601 ataagcaatt ccttcttctg tcacgatatg tgtagtatct tcgctataaa tcatcactgg
    81661 tgcattggct aagcctgctt gtttttgaac agctagtgca tctaattctt cgacaaagac
    81721 tggtttttta tttgaaccat atgtttcaac catttgaaca actaattttt ggcctttccc
    81781 taatggatca tcattgtcgc gaagtgattg ccatgctggt gtagaatgac gacgaccgcc
    81841 aggattatgt cccatgttag gcgcaccgcc aaaaccagat aaacgtcctt ttgttacggt
    81901 agaagagttt ccttcgtaat ctaattgcaa ggttgaaccg ataaacatat cgatggcata
    81961 ttgtcctgca gcttgtgata atgttcggtt actgcgcatc gtgccgtctt taccgacaaa
    82021 aaagacatct gggcgagcag caatatattt ttccatacca acttcgccac caaaactatg
    82081 gatgctttca acccaacctg attcgatggc tggaatcatc gttggatgtg ggttcaatac
    82141 ccagttcttc gcgattttcc cttttaaccc tagtgattca ccataagttg gcagtaacaa
    82201 ttcgatagct gctgtattga atccaatacc gtgattcaaa gattgtacgc cgtgttctgc
    82261 gtagattcct ttgattgcca tcattgccat tagaatttgc aattctgtga tgttttgagg
    82321 atctcgtgtg aataaagctt ctaattgata aggtttatct gctttcacga caacgtctac
    82381 ccagtcacca gggatatcta cacgtggtaa agaatcgaca acttcgttaa cttgaacgat
    82441 cacgatacca tctttgaaag ctgcagcttc gatgattgtt ggtgtttctt ccgtattgaa
    82501 acctgtgtac aagttgccgt ctttatctgc tttatctgca gctactaaaa caacatttgg
    82561 aatcaaatcg atgaataagc gtccataaag ttccaaataa gtatggatat cacctaattt
    82621 cattgtgccg tcttcaatca tttgggcgac acgcaagctt tgtgcaccag cataagagaa
    82681 atcgatcttg cttgcgattc ctttttcaaa aatattcaaa tgttctggtc gtgagatact
    82741 agacatgatc aaatgcagat cattcacttt ttctgcatct actttttcaa gactttctga
    82801 aagaaaactt gcttgttttt gattgtcgcc ttctaataca actttgtcgc cgggagcaat
    82861 cagtttttcc attacttcta cgattttttc agtttctaca tacttgccat tgagcaagtt
    82921 gctgattttt tccaatcgct gcgctttttt ttcgcgttta gaagcccagt tgcggtttgg
    82981 tttttccata attagtcatc tccatttttg atatagaaac gtggcgtcat caataccatg
    83041 ttggtctaga ttgatcgtac ggatcccttt atctacacca aattttgtat gaatcagctt
    83101 tgtcaaagta ttgccggggg gaaattcaat cgtcagatcc attcctaatt cttttgccaa
    83161 gtccatcatt tggttccact gcacagggaa agctaggttt tccaacaaat ctttacgaat
    83221 ctcttctgcg tcctgagtgg ctcttccatc cgtatttttt atatacaaac atctagcatc
    83281 agatagatgg acagactgca tatacggctt gaatttcttg accgtatcat tcatcaagag
    83341 acagtgagat ggcacaggga ctttcagcag cttcgctgtt tgcgcttggt gccgtttggc
    83401 ttctgccaac gtaacggata aaccttcgat actcccagat aacgtatgtt gcatcggaca
    83461 attttcattt gacagataaa ctggatggtc aggatcaaat gtttttgcta caatttcctc
    83521 agcttcgctt ctcgtcacac ctactactac gcccattgca taaccgcttg gataagcttc
    83581 tttcattaag actgcgcggt gatagactag ttccgctgca ttctcaaatc tcaaagatcg
    83641 acaagcaaca gctgcacaaa aagcaccaat cgaatgtcct gctgcaatat caggctgaat
    83701 accgtttttt tccatttcat ctaaataaaa tactgctttt gtcagtaatg ctagctggat
    83761 aaaaaccgta tcttgatagt tttcttcttt atcaactaac cgataccccg tcacattttc
    83821 taaacgttcc atgtacattt cagggatatc cgctaacatc cctaacttct gactgccttg
    83881 tccaggaaat aagaaacctg tactcatgag cctcgcctcc tcagcactta ctttttccac
    83941 tgctatctta gtcaatttct gctataataa aaaatgccaa aaaaagaaaa aaccataaca
    84001 aaaaggtatg gatgggatgg ataattatga aattgcttca tctgcagtat tttaaaaaag
    84061 tattcgaaac aaaaaatgtt acccaagcag ccaaagaatt atttatttct caacctgcct
    84121 tgagccgtgc gatcaaacat ttggaaaacg aattaggtgt ccctttgttt taccatagcg
    84181 gcagaaacat tgagacgacc gtttatgcag aagaatttta tccatatgca gtcaagacat
    84241 tagacacatt agaagaagga atcaaattat tgtcttcggt caatgagaag atcgttactt
    84301 ccgtcatatt gtatttagag gtagcctctg tttctattcc gaacttggtc cgaattttta
    84361 tggaaaagca tcctgatatc caattaacga tcatgcaaca tcatttacca gatgatatta
    84421 ccgatcctgt actgtacatc acttcggaga tgaagcctgg catgaccaat attcctatca
    84481 tgaaagaacc tgtttatgtc gccattccta agaaacatcc tcttgctaaa aaagaacatc
    84541 tgcaattaga agatatccaa cgcaccccca tcttgatgct gtcaaagagc aacgccttcc
    84601 gtcatacact ggatgcagca cttgaagcga aaagtatcga attgacgatc agttcgacga
    84661 cagatgatcc tgcgacatta cgttctattg tcaagcaagg attagctgtt agctttttcc
    84721 caaaagtttc ttggtcttac gataaaaatg atcctttcgt cttgcgggaa atcaaagatt
    84781 tgcccttgac acgaacaatt tatttatctt ctagcttcac agaagatcat cctttgatca
    84841 aaatgattgc aaaaacgatg cgggaatttt atttaggaaa ataaaaaaaa aagagctggg
    84901 acaaaattct tgtcgcagct cttttttcga acaaacggtg ttccagaagt aatttcttag
    84961 aaaataagcc gaaatttccc aaaaatttga gaagcaattt tcgtaaattc cttcttattt
    85021 cttgaagcta aacatttctg tcacaacctc ttctctattg tcctagacat tcattgcgtt
    85081 gatttaaaac ttccatcaat caaatctgct agttcatcta gcttttctat tttacgtaga
    85141 tcaatagaga tccaatgttc tttattcatg tgataggctg gaaaataccc ctcttttcct
    85201 cgcaaaattc cgccaagttc aggatcgacc ttcaaatcaa gaatattgat gatcctatgg
    85261 tcacttgcat catcatagat tttttcttct ggaacagaca tcaggacccc aaaccatttt
    85321 ttgctttttt gatgtctgaa tacgcaataa tcaggaaatt ttttaaaaat atattctgga
    85381 gacaaattgt atgtttcatt gatgtgatcg attagttctt ttttcgttag catctgcttc
    85441 catctctttc ttattgattc gctttattca aagataccac gtaagaatag aaaaatgaat
    85501 acaagtagtt gctaatcaaa tacttcgata tttttctttt ttatcaactc ttaaatgttc
    85561 aatccgcctg tgttggtctt gctaccatct actattaaaa tgtttattat tgtttgccca
    85621 cctatttttt gattttagtg gtatcatttt tcaagttcat gatgaaattc ttatcatcag
    85681 taaatgctcc agaaaaataa acaatgattg aaaaatcagt tgaaacttga ccaccgttta
    85741 ttttctccgt attcttagaa tagaagggag tctgattgat gtattcacta atgaaaaaaa
    85801 tcattaccga aaaagatatt cgacgtcatg tttctttagt agaacaattg ctgaatcata
    85861 caaagataac cgtaaatgaa ttagctgaaa tcatagggac aaccgaacga acgatttttt
    85921 ctgaccttca atctattcgc tctcagctgc ccgaaggctg ggacatcatc agcgatcaag
    85981 caggaatcag tttgcaaaac cagcaaaatt tattaacaaa tgacctttgg gagatttttt
    86041 tcaaacaatc agtcagtgtc gaactgctga aaaatctgct ttttacaaaa aaagttgctg
    86101 tccctgattt tctagccgac catgggcttt cttatgggac attgaaaaga catgtgacta
    86161 aaatcaatca gcgtttagca agttacgact tgcagatcga tttgacgaaa tatacagctt
    86221 gtattcttgg aaaagagcgt gcgattcgta ctttttatca tcgattgctg attcctttca
    86281 ctcataacaa ctattttttc gaggattatt cgatccatga atcccattat tttcaatttt
    86341 taagaaacct cagtcaaact gaactagcgg ttgaaacaga agagattttc ggaacatgtt
    86401 ggttctttat caatacgatc cgtataaaag cgaattgccg attagattct tctatccata
    86461 ccaacagcac actctcctcc ctgtatgact ctgcattgaa aaaattgtat ttaacggaag
    86521 gtatttatct taaagacact gagctttctt ttgcttcttt ctgctttctg gaaagttgga
    86581 attacaacaa taactatgga caagaaaccg ctcgctgcct gcatcattct ccatttttag
    86641 aggtcctcga aacgtttgta gaggaactag cttcagagct gtctcttgat caactaaaaa
    86701 aaacatctct gactgataac ttggctctcc tcatattaaa atatcatgaa tcgccgatat
    86761 tgattgaagc attggaccgt caataccatc gttttttaga aacatatgat cagcaatatg
    86821 cacacttgta tcaacagaaa gagaatttac tgaacgatct aaaaaaagaa atagaaatca
    86881 atgaaccaaa ttactttctc caactcttgt ctctactgat ccaacaaacg attttttcta
    86941 tcaaaccgaa tttgttcaat gtctatttta ttttccaagg agaaccttca tggaaggcgt
    87001 tcttgcagca ggaattaaaa gattacttag gaaaacgtgt ctgcttctta cctatcgaac
    87061 taaccgatct ttccactatt tcttttgaaa aaacagatat cttgatttcc aatttccctc
    87121 tagattctct agatatccct attgtataca tttcttctat tccaacgaaa aatgagctca
    87181 atcgtttgac tgaactcact ttcaaaactt ttttatagta acggctagcg actgtattct
    87241 ctagctgttt tttctttttt gcgaaacagt ttgttcatga tccctttttc tatttctaca
    87301 actaagaata gaagaatcac atttgctcca atcaataact gttgtgtcat cgttaaactt
    87361 actgtaccga tcagctgctg gccgactggt agaaaaataa ccatcccttg caataaagca
    87421 aggataccta atgaaagaaa aagcgctttg ttttgcaaaa gaccttggtt caatgacggc
    87481 ttggacaact ctctgcaatt gatcatgtaa acagcttgag ctaagacgat attttgcaga
    87541 agaatggttt gctgtaagct ttgcccttca aactgcatag ccaataaata ggcaggaacc
    87601 atgatcagta gggagacata gatgatccga aacaaatgat aaccagatag gattccttgc
    87661 tttggatctc ttggtgggcg cttcatgatt tctggatctg gcgactcgaa ccctagtgca
    87721 taagataaag tgattgtcgt taccatattg acccataaaa tctgtactgg ggacaaaggt
    87781 agcgggcgat tcagcataag tgcccaaatc aagatcaatc cttgagctaa tgcagttggc
    87841 aagaagaaat tgatggtttt ttgcaaatta tccaaaatcc gccggccctc ttttacggct
    87901 tttgcaatcg tatggaaatt atcatctcct aaaaccatat cagctgcctg tttgcttact
    87961 tcactacctt tgattcccat agcaattcct acatcggatc ttttcaaagc aggtgcatca
    88021 tttacgccgt ctccggtcat tccgacgatt tctccatttt tctgcaaagc tttaacaatt
    88081 cgcagtttat gttctggtgt cgttcgagca aagacatcga ctattggcac ttgctgaatc
    88141 aactcttcat cagacataag atccaaatcg atcccttcta aaactttggc agtatgtttt
    88201 aagccaattt gttccgcaat cgcttttgct gtgtctttgt gatcccctgt aatcattttc
    88261 actgagatcc ctgcttgttg gcattccttt acagctttga ctgcactttc ttttggcgga
    88321 tcgatcaatc cggcgatccc tgcaaaagtt aattgggtta aagtctcatg cgtgagttcc
    88381 tgtttcgaat ctactttttt ataagcaaat cctaaaacac gctgaccttt tctcgcaaat
    88441 tctgcagctg tctgactcca tgcttcttgt tctgcagaag aaagagttga tttagcaaat
    88501 aatacttctg gtgcaccttt gacgtaaatc accgctcctt tttcctccgc atgcatcgtt
    88561 gccatatatt tgtattcaga actgaacgga atctttgctt ctattttttt caaaggtaga
    88621 ttggctgttt ctgtgtgtcg aatcagcgca acttctgtcg gattgccact taaattttct
    88681 gttttctgtt cttcttttgt ttttaattcc tgacagtttt tcataatgga caacacgcag
    88741 gcttcttctt ttgcagctac atccacaact gtcatttcat tttttgtcaa tgttcctgtc
    88801 ttatctgaac agatcactgt catagaacct aatgtttcta ccgaaggaag tcctttgatg
    88861 atcgcctttt cttttgccat ttcatgtact ccaacggata gaatcatggt caaaacagct
    88921 ggcaatcctt cgggtaccat tgacaccacc aaagcaatcg tagccgaaag aagaatatgc
    88981 caatccatac catatcgaaa tgtcgtaaaa ataactaaga ataggctcaa acaaagaatg
    89041 ccttgaaaaa tttgtttgtt taatcggttg atttttttaa tcagaggcgt cgtttgttgt
    89101 tcgaccgatt gcaatgcttg attgatttta ccgatttctg tcgtgtttcc tgtttctaca
    89161 acgacaccga ctgcagaacc agattgtaca agcgttcctg aaaaacccat atttttctgg
    89221 tcgccgatcg attcttcttc tgtcaaaacg gcatgacttt tttcagatgc ttctgattct
    89281 cccgtcaaaa tcgattcttc cactaataaa tcatgtgctt cgattaatcg gatatctgct
    89341 ggaacgacat ctccggcacg taagacaatg acatctcctt ttaccagttc tttcgcaggg
    89401 attttttctt gcatcccgtt tgatagtact atcgcttctt gtcccatcag ctgcttcaaa
    89461 ccattcaatg attcttccgc ttttctttct tgccagtaac taacgagtcc attgacgatc
    89521 actacgaata aaataatact tccttcaata tattcactag aagcaaattt caaaaaagag
    89581 gcaatgatca acacgatcat cagcagatca gtaaaatgct ttgctatttt tttccatcgt
    89641 tttgtctgct gccttgcttt tatttcatta tatccttgat cagtcaggcg tttctgtcgt
    89701 tcttcttgcg acaagccttc tgttgatgtt tgatagtttt tcaatacatc ttctaccgtc
    89761 aatctgtacc agttcatcct atcccctcct gtttaattga tactgttatt atacgcaggg
    89821 aagttttttc aggcgtatcg attatttcag gggggtctga aataattcgt tttgcaaaat
    89881 gtatctgggc ctaactgata tttctattgc ttattctttt atatacaaaa tttaagaata
    89941 caaaccagat aaccaataaa aaaggaataa agcgtgtcgt gctttcgaat aacaagctga
    90001 aagcaattga agtaaaaaac accaacaaag caagatcttt atatctttgt gtagtgttcc
    90061 gtttcttttc tttaataaat tgaacatgtg cacacaagat cgaagaccac acaaatagaa
    90121 aacaactcgt tgtcatgcct gccaaaagct gaaaaaacaa tcgactatca gctacaaaaa
    90181 aatgtagaca aagaccggca aaaaataaca ttcctgtaat taaaataccg tgtaaaggta
    90241 cgcctttctt agaaagcgca caaaaccaat ggggcaaact tttttctttt gctgtttgat
    90301 ataaaatcct gctagtactg tagactgcac tatttgctga ggacaaagaa gcaaccaaaa
    90361 tcattagatt gacaattgct gctccgcctt ggcaatggat cacttgcagc atagtcacta
    90421 aaggactttc ttttaaatct aaacaatgcc atggaacaac aaataaaatc gacaaaatcg
    90481 ttcctatata gaaaaagaga atacgccaag gcagacagtt gattgctttt ttcaaattct
    90541 tttgcggatc acttgtctcg ccaacggtta agccgatcat ttcaattcca gcaaaactga
    90601 ataaaaccat aggaaatgag actaccattc cagcaaagcc aaacggtagt aattcatcga
    90661 tctgtccaaa attttctttg attccgatag actgggtatg aaaatctgag acactcaatc
    90721 ctatacccaa taagataaaa aggaaaatcc ccaagatctt gatgattgag aaaaaagatt
    90781 ccaattcacc aaaccacttg actgcaacaa ggttgactgc cattaagatc attagtgcgc
    90841 tacctccgct tatcaaagct ggtacatgta caaaccagaa atggatatac aatcctattg
    90901 ctgttaattc cgcaagtcca gctccaagcc agcaaagcca ataagtccaa ttgacaaaaa
    90961 atgcccactt tttgcctaaa taatagtcaa cgaaatcact gatagagtta aatgtactat
    91021 ttgctaaaaa taaatcaccc atggcccgca tcaaaccata aatagccaaa ccgcatatca
    91081 aataaacgag aataacagct ggccctgctg atgcaattgc ctttgctgaa cctaaaaata
    91141 atcctgttcc aattgcgcca cctaatgcga ttaactggat atttcgatta gttagagtcc
    91201 gtttcattgc cggtttttcc atcaagttca cctttttctt tttcaagcag catggcgact
    91261 tcctgttccc aagaaggttt ctttattttt tcaatacaga gtggtactac aaacaaaatg
    91321 acactgatgg ctgtgactgc aattagattg atccatgttc cagctttcat cgtcagtccg
    91381 acagaaaatc cgattgccgc aaataaaaca ataacgacag tccaaactcc aagattgctc
    91441 tttttctctt tttttccaat tctaaatggt cgattcaact ttgcatgtgt ataacgcaat
    91501 ctcaaaactg cgatccccat gatgacatag acgatacagt agataacagt agttgaattt
    91561 acgagcatca aaaatgcttg attgacgcca ggaatcagca aataaaaaag tgcaaagatt
    91621 gagataatga cagactgagt caaaataacg gatttggata cgtcaaattg attcgtcttc
    91681 caaaaattga attttggtgg atacgcacct tttctagcac tttctgtcac tgtctttgct
    91741 ggtcctgagg cccaagcaga taattggact gctacaccaa tgaagacaag taaactaaac
    91801 agattcacaa taagatgtgg caaaccaaga atttggcaat aaatcgaaat agattgcgcg
    91861 atattattca attccatttg tccttttggt acgacatttg ctacaactaa agcattcaaa
    91921 atattgacga aaaatataaa aattaacgcg gcaaatactc cgcgaatata cgttttaact
    91981 ggattttcca atcgagtgat atacacagag gacatttcga taccagtaaa aataaacatg
    92041 atcggcgcaa aataaacaaa tgaggatgca gtcgtagtat ctggtattaa tttgtcccat
    92101 gaaaaactgc ctaatgttcc ggttggtacg atcccaactt tgatccacgc agcaaaccct
    92161 aataagagca tcatcgtcaa aggcacgtac aatcctaacc aaacaccgac ttttccgccg
    92221 atttttgcca tatcaaattt caaattcaaa aaagtgatga tccaataaac gactaaaatg
    92281 acaactaatg taaatttgct gttcaaacca agcggcacat tatcgataat attaccaaac
    92341 aacggagcga gtgctgaagc gaccatcacc atcccaggaa acatttggac ccataacagc
    92401 catgagacaa cgaaccccca tttttttcct agagcattcg atacccaaag ttctggacca
    92461 cctttttggg gaaacattcc agcaaattca ccagagatca atgagattgg aaaagcgtac
    92521 aataatactg caaccagcat gtaaaaaatc atcgtccagc tcgttgctgc tacatctgga
    92581 atatttcgta cacttgctac aagggcgcag gtcattccga taaaggtcat ggtcgtgatt
    92641 tgctttgatg aaccagtatc tttcatcttt attccttctt tcaatagcga catatgtttt
    92701 tgttttcttt tatttttgtt caagaacaga aatgacaagg tttcatcgat tcagtacaaa
    92761 acccagtatc accgaaacat ccattgaacg atcttagtga actgggtttg atacatgaaa
    92821 cgaacgatcc aacttataga acgttttata aaaaagaata tcttggcgag gaatatatga
    92881 aaaacagggg gaaatacaat tgttttgatg aagcaaataa ttgtctgttc tccatatgtc
    92941 tcttgttatt ctttcacaca aaaatcagtt ctattggatg atttcgttta gtttcttttc
    93001 cattgctttg gcgatttttt ttgtataaaa attgaaaatt cgatcatcat tcaaataagg
    93061 agtcatgata gccgcacgta gcagagtgat tttctgttct tttttccatt cttctttcgt
    93121 tagacccatt ctttcaacaa aacgaatcgg agaatcaccg taatcttctt gtgtaaatgt
    93181 agtatgagaa gtaataaacc gttcaccata aacatcgcca tccatataag aagaccgatc
    93241 gaacattttt tcatttaatt cattgatagc gttcaaatct gtacagcctt gttctttgaa
    93301 tacccaattg accatattaa aatcaggatg attcaatgga tagacttcga ttgtttttcc
    93361 tttaacagta aaagtcagat gatcgagaaa ttctctgaat ctttgagctg cctcgattga
    93421 agccccaatc aattgaccat atccggtcac attcaatggc aatacacgat gtgctgtcca
    93481 gactgcggcg gcggttgctc cagcttttga tccttccaaa atataagctc ctaacatatc
    93541 tggagccttt actgattttt caaacacata tggcgcgaaa taagaaatga tatttctcat
    93601 atttttatgt ttgattacga ttcctccagc agcataaggg acatagccca tcttatgagg
    93661 atctatcgtg acagaatccg cttctgaaat agctctgaac ccttcatata cctctttgtc
    93721 aatcgttacg cagtggtgga aaacatgatg ttcttcaaag aattcagcta aggaagcata
    93781 cggcacaaat tctcctgctt cgtttagaaa cagtgaacgc gcatagccgc catatgcggc
    93841 atcaacatgt aaatagaaat agatcccttc atcttttaac ctttctctta attggacgat
    93901 tttatctaca ctgtctactt gaccttcttc tgtcgttcct acgacagcaa ccacacctag
    93961 aattgggatt ttttgtccag ctaattcacg aattgttttt tccaaagcat taatatccat
    94021 tcgataatcc tcttgaactg ggatagcaac catctgatct aagccgactc cgcaaatatc
    94081 taacgccttc atccaagaat agtgttttgt ttgagggacc agccatttcc ctaatctttg
    94141 gatatttttt ccgctacggg aagaagctgc tttgacctca tccatttctt cgtccgtaaa
    94201 gctttcggtc atttccaaaa tttcttcaac agataaattc aaaagttccc actcagacat
    94261 ttttttcact ttttcaggca gcacttcctt gacagctaaa ggaatcgatt tgatgcaacg
    94321 ggcgtaccat aatccttcaa gattagcaat agaaccatct gctgcaatgt gtccccatcc
    94381 gtctgtcata ttgaataatg aagcaaaatc ctgtcctact tctgcttcca tttgcgaagt
    94441 tgccatagaa gattccaatg caacattatt tgggttccac agcatcgcat agttgtaagc
    94501 taataaagca ggcatcaatg tttcagcatt catttgtccc cagtaacggc ctgctgaatg
    94561 ccatgggatc gatcctgcgc gtaatcgctg actgacttca tccaagacct ctatcatatg
    94621 gtcgcgggtg gctagataat ctggagtgag cttatctcct tcgctaattg caggcatatc
    94681 tgaaggaata taattttctc tccatccaag atgttcatct accatcttgt tcaacaacat
    94741 tttataaact ggtccatttt cagctttgtc gcctataaag acggccttga tatccatatc
    94801 tttcattttt cttccctcca tattttgttg gtcaatgtct tgcagataca tgtgtttatc
    94861 tgtaacacct cttcactata gcgccaaaaa tgagaatttt ttttttataa catcaaatcc
    94921 acgtagattt ttacaaacaa aaataaataa agtcggattt ttctgataat tcaacgcaaa
    94981 aaagcgaaca atttttcaat aaatcagtct tctaaaatag ataacctaaa aaaagcgaac
    95041 aaacaaataa aatgactgtc cttcattcac taaacatatt tttatttttt tatattgtta
    95101 aaaattcgca atttattttt taatagaatt atctgttttc caaattttat aacataaaaa
    95161 acctttttta acggcattta tatgcttttt cagaaattaa ctgatgattt caaaaagaaa
    95221 acatgtcata atatttccca tattgtgcaa aaaaatacaa ggcggaggct ctactatgat
    95281 tgaagaatat attgagaaaa atattttaag acagctgttt ttatgtgggc aattctatgt
    95341 aaataaagaa gtcaatctag aaaagctctc caatctcctg catgtttgca aaaccacttt
    95401 actcaatgat atcaataaca taaaaaaaga atttgaagaa cagatcgctt atacacatcg
    95461 ggaaaaggac cgttacactt tatatttttc agaacatata cctcgatgca agatcatgca
    95521 gcaattgtct caaaattcgt tgtttttaaa aacttgtctg ctttatttgg aagaagatga
    95581 acctgattat cttcaattaa ctgaatgtga attcatctct gtcagcaaag cttattcatt
    95641 aaaaaaacaa gtattagctt attttaatga ctgcgggatc gaaatcgacc gctactcccc
    95701 tcgattcact gaaatggaaa gacgtctgct gcttcttaat gtgtcgtatc gtttaggcgg
    95761 ttttaattct tgggagctac ctgaatcgtt ttttgaacgt gccgatcgtt tcattgaatc
    95821 cgtaacggaa aatagtggca gattttatga taaagaaaat aaagaaatct tatcgattgg
    95881 ttttgctatc agtttcctac gccagcaagt gtgtgctgtg acaatagatt caaaatttat
    95941 cgaagaaatc aaaaaacgtc ctatttacaa ttatgtcgaa tcagcatggg aaaacactga
    96001 tttccaaacc tattataaaa aagaagaatt cgcctttatt ttgacactat tcaatctttg
    96061 taattatggt ttccattctt atcagttgat tgcggaagac tttcaacagc tacaccaagt
    96121 gtttattgac aatactcccg aaataaaaga actagttgct acctttgaat ctcacttcaa
    96181 tcaagaatta ttcggaaacc aaccgttcga acgtgcgctg attcatctga tgcgttcggc
    96241 ttgggataac tatcaattat tcatgccaga aaaattttat cttttaaatg aggaacagac
    96301 aaatttatat aaagaagtcc agacaatttt ttccagctgg tccagccagt taccttatga
    96361 tctacggttg aatcctaatt gcatgcgggc ttttgtgatc gaattgagcg gaattctccg
    96421 tctgacaaaa gaacatctga ctatctatat cgtcacaaat tcggatgttc attatctgat
    96481 ttatcgggaa gccttggaag ctgtaactac tttcgatttt caagttgcac caacaattta
    96541 ttcaagtata tctgatataa agaagtatgc gcagcagtcc tcaaaccggg tattatgtga
    96601 acgtacatta tatacaccag atgcggtcca atatgaaaat attattccta tttcgatcaa
    96661 tacgatcgat cgagctatca tttcagctgt gcaaaacaaa taaggggctg tgacaaaaat
    96721 catgtcacag cctcttattt gttgaagatg cccatttctg taacaatctc ttgatacacg
    96781 tcaggctcac aacctcactt attttggaca tctacgggtc cgatctcttt atttaaaaaa
    96841 taagaaatga tggttcggat aactaccaac gccgctagtt ggaaaatatc ctgcaaggta
    96901 ggtttgataa tcgattcgat gatcccagct gaaacaagaa tttccaaact tagaagtata
    96961 tagcctccca acatcttttt aatagcattg ttctcgctga ctcggtcgct ttgcactttt
    97021 gtatggacaa ataaatattt caaaaaatcc ttgattgata gacaaacacc ccaaaccaat
    97081 aaacagatag caaagatatc aagtcccagt acaagttttt cgaaatatgg aagaagaaac
    97141 tgcatcaact ctgtcgtcat cctacctctc ctcttctttg tttttctttg tcttctattt
    97201 cctgattcaa gaaataagaa atgactgttc gaatgataat aataagtgca agcttcaaaa
    97261 tatctgtcca agtcggcttg ataactgact cgatgatatc agcaacgact agtacttcca
    97321 agcttaacaa aatataactt gctagcagtt ttcttgtatc tgcattacga gtattacgtt
    97381 ctgcatagtt tttcttgaca tgagaccaat caaaaagttt gaatagaaca agaacgatcc
    97441 cgacaattaa gataccgata gaacaaatat ttaaaatagc aatgatccat tctagaaatt
    97501 caattaaatt tgagcgaaac atatacgcta cctactttct tttaatttgt tcctattctt
    97561 ttattgtaaa agaaagttac cttgttcgtc tatttaaaag ttgttctaat gataacggtt
    97621 cgcttaaatt tttctttttc actctcccat ttttctccct ccatccataa atcgtggaag
    97681 tatccaaaac aacgtagcaa gttaaaataa ggcttagtcc gtcatcagct tttcaaagaa
    97741 gcactgtctc ggtgcttttt ttgtacccaa atttctaaaa atagaaccat acacctcctc
    97801 aaatcttttc ttcttaccta ccctattttt atttacagga aaatcagaca cttcttcttt
    97861 tttgtcaaaa tttccttttt cttctcgtcc tatcatttgg cattctaata aaaacgaact
    97921 atccttggat atagaaagag aaaacaagga ggcgtttttc atgagtaaaa aattaatcaa
    97981 agtcggcatc ggtttaggtt tgcttgccct tggcgctgca tatctaggaa aaaagacagg
    98041 actattcgaa gatgacagtc atttatatga tgaattcgaa tcaatctagc atcctattta
    98101 gttgaatcac tacggacata cttggaagac attggaggaa tcacaatgag aaaaagtaaa
    98161 gcaataatga ttggtgccgg tattgccaat atggcagcgg ctgtttattt gattcaagaa
    98221 ggcaaatgga aaggggatca gatcaccttt tattcattgg atgatcacgg ttcaaatgat
    98281 ggtgcaccga ccgacactgt agtggatgaa tattggaata aaaaccatcc attagaaaac
    98341 caaaaaggct atattgctcg aggcggtcgc atgcttaatt accgtaccta tgtagatttg
    98401 atggatctgt taagtcgaat accttctgtt actgagccag ggatgactgc tgaagaagat
    98461 acgagagatt ttgatgcaaa acaccgaacc tttgacaaag cacgtttgat ggaaggtggc
    98521 aaaggaatca ttgatggcgg aaaactggga ttcaataata aagaccgtat tcttctgact
    98581 aaactgattg ctatgcctga ttcagaagaa gaaaaactag acaatatcac tatcgaagaa
    98641 tatttcaaag atgatccaca cttttttgaa acaaacttct ggtttatgtg ggaaacaaca
    98701 tttgctttca gaacacgtag ttctgctcaa gaattgcgtc gctatatgca tcaaatgatt
    98761 tatgaattca ctcaaatcga acatctagtg ggcgtcaatc gaacacgtta caatcaatac
    98821 gaaagtatta tgcttccttt gatcgagtac ttgaaagaac aaggatgcaa aatcattttg
    98881 aaccgccgtg tcactgactg ggaattcaaa gaaacaccga tgcaagatga aatcactgtg
    98941 actggtttga aaattaccaa tacactgact caagaagaag aatacgttgt ggtcgatgaa
    99001 gatacagcag ttattttcac taatgggtcc attacagatt cagctacttt aggagattac
    99061 gaaacaccag ctgtagaaaa tatggattat ggtgcagctt ctagtctctg gaaaaaagcc
    99121 agtgaacgtt tctacaactt gggaaatcct gacaaattct ttgctgatcg agatgcaagc
    99181 gaatgggtca gctttaccct gacgacgaaa aaccatttgt tgttgaatga aatcacccgt
    99241 atcacgactc aagaaccagg aaatgccttg aattcattta tttcaaccac accgatcacg
    99301 ccgttaggcc aaaaagatgt caatatgtct atcgtcgtgc atcatcaacc gcattttacg
    99361 tctcagaaac caaatgaaac agttatttgg ggttatttcc tttatccaag acgacgtggc
    99421 gaatttgtgg ataaacagta tattaaaatg aatggaaaag aaatgctaga agaactgatt
    99481 ggacaacttt caaaagtaga tcctggacca gtgaatattc gtgaaaaaga aacagaaatt
    99541 ttcgacagcg taataaataa tatccctgtc tatatgcctt atgcttccgc gttgttcaat
    99601 aatcgtgcca aaagcgatcg accaaaagtc attcctaaac attcgaccaa tctggccttt
    99661 acaggagaat ttgtcgagca gccttatcag atgatcttta ctgaacaaag tgctgtacgt
    99721 tctggagaaa tcgctgcttt ccattttgcg ggtattccta tgtcccgtct tgtcaaaaca
    99781 ccgcgttacg acaaagatat tcctactcta gctcgtgccg caaaaaaaat gtttgaataa
    99841 tcaagaggtt gtgaaaaagc tgccctgcat caagtaataa gaacaaccag gctaaaacag
    99901 cttcttatgt ttttgatttg gttggactta ttaccgcaga tgcaagcttt tgaacaccgt
    99961 ttaccaagag gttgtgaaaa agctgccctg catcaagtaa taagaacacc caagctaaaa
   100021 ctgcttctta tgtttttgac ttggttggac ttattaccgc agatgcaagc ttttgaacac
   100081 catttaccaa gaggttatga aaaagctgcc ctgcatcaag taataagagc agccaagcta
   100141 aaacagcttc ttatgttttt gacttggtta gacttattac cgcagatgca agcttttgaa
   100201 caccgtttac caagaggtta tgaaaaaggc gtttagtttc gagtatgaag aaaaattttg
   100261 tgaaaatggt tcctcacgtt tttgcataaa tttgacttaa taccgagaaa ctgatccctt
   100321 ctgtcataac ctctttttat ttatgtctgt ttctttttga aaacaactat tttttcaacg
   100381 tttactctct tgccaatcca acatcatcta acggatacaa ctatttcaat gattaccatt
   100441 acactaaaaa atcggaaaca cacctctccg aacacaaata cataagacta tagaatgttt
   100501 catttaagaa aaaaagcgtt tcattatcaa aaaggtaaga tctcctttaa aatgaaatta
   100561 tctgtagtac taataatgca gacaatttta tgaatctgaa aggagcatct ccaatgaaag
   100621 cagtcacttg gcaaggaaaa cagaaaatgg aaatcagaaa cgtagatgat ccaaaaatat
   100681 tagaaccaac agatgcaatc atccgtatca cagcaacagc catttgcggc tccgatctgc
   100741 atctttacca tcatggtgaa gcagttttgg aaaaagggta tgttgtagga cacgaaccaa
   100801 tgggaatcgt tgaagaagtg ggatctcaag ttcaaacatt gaaaaaaggg caacgtgtgg
   100861 ttatcccttt taatattagt tgtggtcatt gtcatttctg cctgaatcac atggaaagcc
   100921 aatgtgatga atcaaatcca gatcagttat atggcgggct tttcggattt ggcaagttga
   100981 acggtaatca ttggggtggt caagcggaat atctaagagt tccttatgca gactctactt
   101041 catttgttgt accagataat gatcttcctg atgaaaaagt tttatttcta tcagatattt
   101101 tgcccacagc ttattggagc gttgaaaacg caggagtaaa aaaaggcgat acagttgtga
   101161 ttctaggttc tggtccagtc ggtctattcg ctcaaaaatt cgctgttatg gctggagcag
   101221 agcgcgtaat cgcagtagat ccagtacagc accgtctaga taaagcggct aattacaatg
   101281 gggttgaaac ttatttctta gaagacacgg cacaagctgg aacagaattg tatgaactgg
   101341 ctaaaggtgg cgcagatgtc attatcgatt gtgtaggaat ggacggatta gagcctgtca
   101401 aagaaaaagc gaaaaattta gtaagcttac aaagcggcac aatctctcca ttacagatgg
   101461 catcgcaagc tgtcaaaaaa tttggaacag tccaagtaac tggtgtttat atgactccag
   101521 cttcttctta cccgctgcaa gaatttttta tgcgggatat cgctgtcaag catggacagg
   101581 caccaattat ccatctaatg ccaaaaattt acgcaatgat tgcagaagga ctattcgatc
   101641 ctacacaaat cattactcat tcgctgccac tatcagaagc agcacaagca tatgagatct
   101701 ttgacaaaaa agaagataaa aatataaaag ttgttttgaa accttgaatt cagtaaaaaa
   101761 tacaggtgat tttctttatg cccaaaatca aacgaaatac ccatgagatc gaaataggaa
   101821 aagaagaaga tatcgaaata cgaggacgtc gcttccgctt ctatttccaa aatcgttaca
   101881 cattgatctc actggctgtc gatttattaa ccgggatttt ctatattttt ggaagccttg
   101941 cttccttaac taaaatcccc gatcgatatg gcacctattt ttatttggct ggtgctattt
   102001 tcttgacgat tcgtcctatt ctcagaatcg taaggaacat ttttatttac gacgaaaaaa
   102061 aagcaatgaa gagaacaagc aaaaaaaaag aggcatgaga atttttcaaa tctcatgcct
   102121 cttttttcac cctatcgtat cactttgata cagacgagcg gtcgtcccac tttcttcctt
   102181 gaccattgtc aaaaatgtcc actcgtatcg ttcataaaac gtggtatgat ctgtaattaa
   102241 gtaaagtttt tcgtacccaa gttgatgcat ttcttttctg atttccgcta atatccgctt
   102301 ggctatcccc tgcttacgct tttccggttc aacaaacagg gcacaaagat ttggtgtcag
   102361 atcagggcgg ttatggaagt cgttttcaat gacgcccgct cctccgacga tggtttcttt
   102421 ttcatctaag accacatacc attgaggaat actttcctta ttagcgattc cagtacgaat
   102481 actttcctca tacacaacag caggaactcc ccattttgat gaaaaccaat tcgcgctttg
   102541 ttttactaat tctgggtgtt ctcttaattt gatccagtta tatgtaacca atgtttaaac
   102601 ctccgactaa aataaaacgt ttacaaaaat tatacaagtc tttatgaaaa ttagcaatga
   102661 caacaatagt gatgtaaaaa aaaaacggaa aacaatcact tgttctccgt tttttgatta
   102721 atcaagcatc taaagcttct tttcttcttt cttggatcgt agctaccttg acgaacggta
   102781 gatagatcaa aatagaaaga accaaattga cagcggctag tacaccacct gcaatacttt
   102841 ttgttgccaa tacaccgcca ataattggtg gagttaccca tggaggcata acggtagctg
   102901 ctggcactaa acctgtagaa gtcgcaaagt aagcaacact aactaagacc attggtgtca
   102961 aaataaatgg aatgaacatg atcgggttca acacgatagg taacccaaac atcgttggtt
   103021 cattaatatt gaagacacct ggcgcaatcg acaagtttgt tacaaccata tatggtttgt
   103081 ttttacgtcc tactaaataa atagctaaca gtaaacctaa agttgcacct gttcctccta
   103141 agttgacaaa gctgtcaaag aaaggtttgt tcacgataaa cggtgcgcta tgcccagctg
   103201 cgattgcatt aacgtttgct tcaatggctg gcgcattgat tgtttgcatc aaaggatcga
   103261 ccatattcgc tccgtgtaaa ccaaagaacc ataagaatgg tgtgataaat gcaagcagta
   103321 aggcagatgg ataagagttt gcaagtccca taaatggttc ttggaccact gtatagaaag
   103381 aacctacgat atcatcaaca ccgaatgcag caaaaattgc agcaactaaa gcaaacgcag
   103441 agatagtgat cattgctggt agtaatgaag caaatgcttt tgcaactgcc ggtggcacac
   103501 catcaggcat tttgatgatc aatttttcat ttccgcttaa acgtacaaag atttctgttg
   103561 aaataatccc aacaataata gcaataaaca aaccgtttga gctcatacct aatgctccgc
   103621 ctaaagcgaa gaaagagcct aaagaaatca cacctgcgga aacaccgtct tttcggtagc
   103681 cgttagctaa atgataagca agcaagaaag caatcaagac agaaagaatg gcaaatgtac
   103741 cgttccaagc agcagccccg aatcctttcc atgattcacc accaaaaatt gagttcatca
   103801 attcttggaa cccgggaatc ggtaagttat tgatcattac tgctaatgct cctaagatca
   103861 ttaacggcat actcaccata aatgagtccc gaatcgcaac taaatgccgt tgtgcaccaa
   103921 tttttgatgc tacaggtata aaatgtttct ccataaatgc aacaaattta tccataaatc
   103981 ttccctcttt tctttactgt agattacgcg ttcaatcgac gatacagatc aatgatctct
   104041 tttgctaaat ctgtaaaagc tatagatgtc atcagatgat cttgactgtg gaccgtcaaa
   104101 agcgtgactt caacgtgatt tccttgtgct tcttgtgtca gcatctctgt ttgagagtga
   104161 tgtgcttgga ctaaagattc ctctgcatct ttgatttttt catctgctaa agtgaaatca
   104221 ccttttttcg cagcagcaat cgcttccatt gcatcgcttt ttgcatttcc gccaaacatg
   104281 atcagaccca tgatggcttc tagatttttt tgatcttcca tttattgtat cctccgataa
   104341 tttttattat ttgtttatta gtttttctgc ttggtcgagt actttttcac cattcatcat
   104401 gccatagtca gccatattga ttacatctaa aggaatgcct ttaggtgcta gcttttcagc
   104461 aaattgattt tgcataaagc gtacttgcgg tcctaaaagt aaaacgtcta catttttaga
   104521 ttctagttga ttatccgcat ctgaagcaga tacagcaaag atgtctgctt ccattccttt
   104581 tgcttctgct gccttttgca tttttgtgac taggagactt gtactcattc cagctgaaca
   104641 tacaagcatg attgttttct tttccatttt aaacacgttc ctttctatac ttacacttgt
   104701 atataagcaa gtagcgtgcc aactttaaaa gcgctttaaa aagttgatat catcacattt
   104761 aaggtctata ccaagttgca tacacactaa aaaagaaagc gcacactaaa cacacaaatt
   104821 aatttttatt accttttttc ttttaacgtg cacaaaaaaa gttgtgacac aaaacttgtc
   104881 acaacttttt tcaaataaac ggtattcaaa agcttgcatc tgcggtaata agtccaacca
   104941 agttaaaaac ataagatgtt gtttttactt tgctattctt attacttgat gcaggacagc
   105001 tttttcacaa cctctcaata aacggtgttc aatcagctga ccctgggtat tagctcaaaa
   105061 cgctggattc acaacctctt ttatttcaaa taaccagtaa atacaatgaa catctacaaa
   105121 aaacttctat ttatttatag atttcgtcag gcaaatccaa ttctctctta tcaatcaaag
   105181 tctgatacca cgaagcagat tttttcaatg ttctgcttcg ttcatcgttc aattcgattc
   105241 gaactaatcc atatcgattc ttaaatgcat tcattggtga cacacagtca gtgaatgccc
   105301 ataacatata gccttcgcaa tttgcgcctt cttctgttgc tttgatcaag taatgcaaat
   105361 gctgtccgat aaattcgata cggtaatcat cttgcacgat tcctttctca tccatatact
   105421 gttcttcata ttctcttccc ataccgtttt ctgttatcag ccaagggata ttatgataat
   105481 tttcttttag atacatggct atatcataca tgattttcgg atagatttcc catcccctgg
   105541 aattattcat tttcttccca ggtaaatcaa agacttcata atatcgttca ggatggaaag
   105601 gtgtctcttc attccattga taacgagggg cgcgaacgcg tttaggataa tattgattga
   105661 ttccaaggaa atctactgta tgatgctgaa tcgtttctaa atcctctgtt gcaggatcga
   105721 aataaatcga ttgtttttga cacaactcca ggaactcttc tgtgtagtat ccttttacca
   105781 tcggatcaaa aaatactcga ttataaaaca aatcatacat ataagcagct ttttggtctt
   105841 ctggagaatt ggatcgagca tagaccattt caggatttaa aatacagcca atccttccac
   105901 cataatttcc gctgcggtaa atctctactg ctttagccgt tgctaaaact ttatgataat
   105961 tccacatcat ccactttttt gtgttttgtt catgcggcca gcgaacagca tccaaatagc
   106021 aacgcgtttg gggaacgatt ggttcgttga atgtaaacca gttttttacc ctatcaccgt
   106081 aacgatcaaa ggcaatttga gcatacttag cataaaaatc aactactttt cttgaagacc
   106141 agccatcata tttttccaaa agaaaagctg ggacttcata atgttccaaa caaatcatcg
   106201 gttctacgtc tgcttcgatc aaagagtcga tcatttcact tatatgctga gcatattctt
   106261 catctactat acagttctca taatcagtaa aaaaacgagc ccaattgata gaagtccgat
   106321 aatgtgtcag atggatggat ttcatcagat ccacatcctg ctggtattgt tccataaaat
   106381 tagttgctac ggctgggcca tacccattat gccaaacaaa atgttcattt ttataccagc
   106441 tatctataaa cgaatcctgt ccttcttttt ttcctttcca accttccgtt tgccaagcag
   106501 aagatgcagc accaagaata aaattttttg gaatagtaat tttcatgatt tcctcctgtt
   106561 ttttagatcc catcattttc cacacgattt gctactttta caaatggcag atagatcaaa
   106621 atagaaacaa taatacaaac aagttgcgta ataactgcac cgatatttcc tgctgttgcc
   106681 agataagcat tgacgatcgg cggcattggc caagggacca ttacaactgc tttcgccgca
   106741 aatcctaaag cggttgcaaa ataaccaatc gttccagtga taagaggcgt taagataaac
   106801 ggaatagcta aaattggatt cagcatgatc ggcataccaa aaataactgg ttcattgatg
   106861 ttgaagatcc caggagcaag ggataacttg gtgatttgtt tcatatcttc ccgttttcca
   106921 actaacaata ctgcaatcag taaaccgatc gtgactccag acccgcccat actcatatac
   106981 atatcccaaa atggcatagt aataatgttc ggtacttctt ttccagcttc aaaagcttcc
   107041 gtatttacag caattgccgc taaaagcaac ggttcccgta tcggcttcac catttgattt
   107101 ccatggatac caatcaccca aaagacttgc gcaataaaca tcaatagcaa aatacccggt
   107161 aacccttgta cgacaccttc taatgggcgt tgtacgacat tgtaaatgat atcataaagg
   107221 tacattcctg taagttcttt gatgataaat cccgcagccg cgatacccga tacagtcaga
   107281 atcgtcggga ataaagcaga aaaactagca gaaacattcg ttggcacggt atcaggcatt
   107341 ctcagctgta gtttcttctg tttcctcaac cagcaataaa gttcaataga aaggatggag
   107401 accaacattc ccaaaaataa ccctttcgta tctgtatatt gtttagccaa tacgttttct
   107461 actataacag tctgattttc attcactaat tcataaacag ttggattaac agataaataa
   107521 gacatcactg cgatgatacc agggaataca ccatccactt tattcagctt ggctaattcg
   107581 atccctatca gaaaaacagc atagatggtc aagaaactta gtgtgacata gctgatggca
   107641 gatgcgatag gctttaattc ttctaaaaaa cgcaagaaac ttatctgtgc taagccattt
   107701 tccgagtcaa agaccattgc tgaaaacaat gtgccaaaag cacccgtaat aattaccgga
   107761 atcaatgcag caaatgcgtt ttttatcacc atgatatacc ttaaattatt gattctcgtt
   107821 gccacgttcc ctaaaacatt ggctaattta tccataaaac tcattccaga tcccctcatt
   107881 cctgcttctt ctccttgacg tcatctcttt ttgtctatta gtcagcgctt acatttcgat
   107941 gaacagaaac tatttactcc tcttttttac caaatataaa acaaaaattc atctgatgta
   108001 tttatcataa aatacatcag atgaactgtc aattagtttc tttttctcct attattttct
   108061 gtaattctct ccgatttatt gccatatgga cagtcattgc atcaaacgca gcaagtgcat
   108121 tccgcctttc gatggcctga acgatctctg tatgaatatc gatcgtctcg attttcagat
   108181 gctggatatc ataattttta ttaaacaaag caattgattc attaatgatt gggataatat
   108241 gcagcaaggc tacgtttccg ctagcttctg caatcatcgt atgaaaatcg atgtctaatt
   108301 gaacatgttc ttgtgtgcct tctcgaaaag aagtttcaat cttttgcgtt aattttttca
   108361 tttggacgat ttgattcttc gttgcatatt ccgctgccaa acctgccatc ttaggctcca
   108421 ataaatatct cagttcaaat aagtctcgta tcatccgatc ctgatcttca atcaaagaaa
   108481 aaccgagtgg gtcattggca atccctcgct tatcactgac aaatgtcccc gctccttgcc
   108541 gaacttcaag gatattcctg gaagctagag cccgcacagc ttctcgcacc gtgcttcgcc
   108601 ccacctctaa ataatcggac aattcatatt cattcggcag tttatctcct acttgcaact
   108661 gcatttcctt taaatatcta aggatcttgt cagtagttac ttctactagg gttttatttt
   108721 cttccaaacc acatacctcc ttttcatctg atgtattttt tcgtaattat tataacacgt
   108781 ttgaatcatc tgatgatttt ttgtatacaa aattgattaa tccgttcata gacatacaaa
   108841 cgaagaagat atttaccata aaaaagacta gga
//
LOCUS       DAFENC010000004       107374 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.004, whole genome shotgun sequence.
ACCESSION   DAFENC010000004
VERSION     DAFENC010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 107374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 107374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..107374
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.004"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            201..1070
                     /locus_tag="LP493_000354"
     CDS             201..1070
                     /locus_tag="LP493_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL2132533.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMINFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            1279..2304
                     /locus_tag="LP493_000355"
     CDS             1279..2304
                     /locus_tag="LP493_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBL2132534.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            2343..3293
                     /gene="manA"
                     /locus_tag="LP493_000356"
     CDS             2343..3293
                     /gene="manA"
                     /locus_tag="LP493_000356"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HBL2132535.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            3387..5090
                     /locus_tag="LP493_000357"
     CDS             3387..5090
                     /locus_tag="LP493_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL2132536.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            5092..7125
                     /locus_tag="LP493_000358"
     CDS             5092..7125
                     /locus_tag="LP493_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBL2132537.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            7136..7576
                     /locus_tag="LP493_000359"
     CDS             7136..7576
                     /locus_tag="LP493_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL2132538.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(7776..8903)
                     /locus_tag="LP493_000360"
     CDS             complement(7776..8903)
                     /locus_tag="LP493_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2132539.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLLDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(8906..9583)
                     /locus_tag="LP493_000361"
     CDS             complement(8906..9583)
                     /locus_tag="LP493_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2132540.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            9847..11613
                     /locus_tag="LP493_000362"
     CDS             9847..11613
                     /locus_tag="LP493_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HBL2132541.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            11628..12065
                     /locus_tag="LP493_000363"
     CDS             11628..12065
                     /locus_tag="LP493_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL2132542.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            12078..13229
                     /locus_tag="LP493_000364"
     CDS             12078..13229
                     /locus_tag="LP493_000364"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBL2132543.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(13291..13989)
                     /locus_tag="LP493_000365"
     CDS             complement(13291..13989)
                     /locus_tag="LP493_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HBL2132544.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(13982..15334)
                     /locus_tag="LP493_000366"
     CDS             complement(13982..15334)
                     /locus_tag="LP493_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HBL2132545.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(15557..16957)
                     /locus_tag="LP493_000367"
     CDS             complement(15557..16957)
                     /locus_tag="LP493_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HBL2132546.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            17118..17855
                     /locus_tag="LP493_000368"
     CDS             17118..17855
                     /locus_tag="LP493_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HBL2132547.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            17980..18459
                     /locus_tag="LP493_000369"
     CDS             17980..18459
                     /locus_tag="LP493_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HBL2132548.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            18456..19223
                     /locus_tag="LP493_000370"
     CDS             18456..19223
                     /locus_tag="LP493_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132549.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            19453..20022
                     /gene="lepB"
                     /locus_tag="LP493_000371"
     CDS             19453..20022
                     /gene="lepB"
                     /locus_tag="LP493_000371"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBL2132550.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(20126..20728)
                     /locus_tag="LP493_000372"
     CDS             complement(20126..20728)
                     /locus_tag="LP493_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBL2132551.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            20834..21303
                     /locus_tag="LP493_000373"
                     /pseudo
     CDS             20834..21303
                     /locus_tag="LP493_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            21409..21993
                     /locus_tag="LP493_000374"
     CDS             21409..21993
                     /locus_tag="LP493_000374"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HBL2132552.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            21996..23069
                     /gene="prfA"
                     /locus_tag="LP493_000375"
     CDS             21996..23069
                     /gene="prfA"
                     /locus_tag="LP493_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HBL2132553.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            23062..23901
                     /gene="prmC"
                     /locus_tag="LP493_000376"
     CDS             23062..23901
                     /gene="prmC"
                     /locus_tag="LP493_000376"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBL2132554.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            23894..24073
                     /locus_tag="LP493_000377"
     CDS             23894..24073
                     /locus_tag="LP493_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132555.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            24095..25120
                     /locus_tag="LP493_000378"
     CDS             24095..25120
                     /locus_tag="LP493_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HBL2132556.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            25311..26555
                     /locus_tag="LP493_000379"
     CDS             25311..26555
                     /locus_tag="LP493_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBL2132557.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            26708..27655
                     /locus_tag="LP493_000380"
     CDS             26708..27655
                     /locus_tag="LP493_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL2132558.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            27789..28418
                     /gene="upp"
                     /locus_tag="LP493_000381"
     CDS             27789..28418
                     /gene="upp"
                     /locus_tag="LP493_000381"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HBL2132559.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(28557..28799)
                     /locus_tag="LP493_000382"
     CDS             complement(28557..28799)
                     /locus_tag="LP493_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132560.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            28920..28992
                     /locus_tag="LP493_000383"
     tRNA            28920..28992
                     /locus_tag="LP493_000383"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:28953..28955,aa:Thr,seq:cgt)
     gene            complement(29111..29749)
                     /locus_tag="LP493_000384"
     CDS             complement(29111..29749)
                     /locus_tag="LP493_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBL2132561.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(29872..30504)
                     /locus_tag="LP493_000385"
     CDS             complement(29872..30504)
                     /locus_tag="LP493_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBL2132562.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            30855..31154
                     /locus_tag="LP493_000386"
     CDS             30855..31154
                     /locus_tag="LP493_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBL2132563.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            31649..33814
                     /gene="acm"
                     /locus_tag="LP493_000387"
     CDS             31649..33814
                     /gene="acm"
                     /locus_tag="LP493_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HBL2132564.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(34086..34571)
                     /locus_tag="LP493_000388"
     CDS             complement(34086..34571)
                     /locus_tag="LP493_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBL2132565.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    34661..35006
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            35051..35692
                     /locus_tag="LP493_000389"
     CDS             35051..35692
                     /locus_tag="LP493_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBL2132566.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            35711..36346
                     /locus_tag="LP493_000390"
     CDS             35711..36346
                     /locus_tag="LP493_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBL2132567.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            36364..37179
                     /locus_tag="LP493_000391"
     CDS             36364..37179
                     /locus_tag="LP493_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL2132568.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            37498..38934
                     /locus_tag="LP493_000392"
                     /pseudo
     CDS             37498..38934
                     /locus_tag="LP493_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
     gene            39123..41570
                     /locus_tag="LP493_000393"
     CDS             39123..41570
                     /locus_tag="LP493_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBL2132569.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            41800..42867
                     /gene="rlmN"
                     /locus_tag="LP493_000394"
     CDS             41800..42867
                     /gene="rlmN"
                     /locus_tag="LP493_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBL2132570.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(43060..44163)
                     /locus_tag="LP493_000395"
     CDS             complement(43060..44163)
                     /locus_tag="LP493_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBL2132571.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            44715..45263
                     /gene="aac(6')"
                     /locus_tag="LP493_000396"
     CDS             44715..45263
                     /gene="aac(6')"
                     /locus_tag="LP493_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBL2132572.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            45809..47470
                     /locus_tag="LP493_000397"
     CDS             45809..47470
                     /locus_tag="LP493_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL2132573.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(47540..47887)
                     /locus_tag="LP493_000398"
     CDS             complement(47540..47887)
                     /locus_tag="LP493_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HBL2132574.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSTLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            47971..48912
                     /locus_tag="LP493_000399"
     CDS             47971..48912
                     /locus_tag="LP493_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2132575.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            48913..49956
                     /locus_tag="LP493_000400"
     CDS             48913..49956
                     /locus_tag="LP493_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2132576.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            49962..51032
                     /locus_tag="LP493_000401"
     CDS             49962..51032
                     /locus_tag="LP493_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2132577.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            51022..51975
                     /locus_tag="LP493_000402"
     CDS             51022..51975
                     /locus_tag="LP493_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2132578.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            51987..52997
                     /locus_tag="LP493_000403"
     CDS             51987..52997
                     /locus_tag="LP493_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL2132579.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(53282..54103)
                     /locus_tag="LP493_000404"
     CDS             complement(53282..54103)
                     /locus_tag="LP493_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBL2132580.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(54200..54478)
                     /locus_tag="LP493_000405"
     CDS             complement(54200..54478)
                     /locus_tag="LP493_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132581.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            54746..56755
                     /gene="metG"
                     /locus_tag="LP493_000406"
     CDS             54746..56755
                     /gene="metG"
                     /locus_tag="LP493_000406"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HBL2132582.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(57234..57821)
                     /locus_tag="LP493_000407"
     CDS             complement(57234..57821)
                     /locus_tag="LP493_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132583.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            57996..59318
                     /locus_tag="LP493_000408"
     CDS             57996..59318
                     /locus_tag="LP493_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2132584.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            59473..60249
                     /locus_tag="LP493_000409"
     CDS             59473..60249
                     /locus_tag="LP493_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBL2132585.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            60242..60811
                     /gene="rnmV"
                     /locus_tag="LP493_000410"
     CDS             60242..60811
                     /gene="rnmV"
                     /locus_tag="LP493_000410"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HBL2132586.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            60804..61688
                     /gene="rsmA"
                     /locus_tag="LP493_000411"
     CDS             60804..61688
                     /gene="rsmA"
                     /locus_tag="LP493_000411"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HBL2132587.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            62139..62768
                     /locus_tag="LP493_000412"
     CDS             62139..62768
                     /locus_tag="LP493_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132588.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(62892..64001)
                     /gene="ugpC"
                     /locus_tag="LP493_000413"
     CDS             complement(62892..64001)
                     /gene="ugpC"
                     /locus_tag="LP493_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HBL2132589.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            64210..64632
                     /gene="mgsA"
                     /locus_tag="LP493_000414"
     CDS             64210..64632
                     /gene="mgsA"
                     /locus_tag="LP493_000414"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HBL2132590.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            64955..65491
                     /locus_tag="LP493_000415"
     CDS             64955..65491
                     /locus_tag="LP493_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBL2132591.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(65531..67294)
                     /locus_tag="LP493_000416"
     CDS             complement(65531..67294)
                     /locus_tag="LP493_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2132592.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(67297..69012)
                     /locus_tag="LP493_000417"
     CDS             complement(67297..69012)
                     /locus_tag="LP493_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2132593.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(69791..70015)
                     /locus_tag="LP493_000418"
     CDS             complement(69791..70015)
                     /locus_tag="LP493_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132594.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            70206..72983
                     /locus_tag="LP493_000419"
     CDS             70206..72983
                     /locus_tag="LP493_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL2132595.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            73064..73483
                     /locus_tag="LP493_000420"
     CDS             73064..73483
                     /locus_tag="LP493_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HBL2132596.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            73495..73965
                     /locus_tag="LP493_000421"
     CDS             73495..73965
                     /locus_tag="LP493_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2132597.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            73982..74761
                     /locus_tag="LP493_000422"
     CDS             73982..74761
                     /locus_tag="LP493_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2132598.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            74748..75569
                     /locus_tag="LP493_000423"
     CDS             74748..75569
                     /locus_tag="LP493_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL2132599.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            75586..76635
                     /locus_tag="LP493_000424"
     CDS             75586..76635
                     /locus_tag="LP493_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL2132600.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            76648..77652
                     /locus_tag="LP493_000425"
     CDS             76648..77652
                     /locus_tag="LP493_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL2132601.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            78285..79304
                     /locus_tag="LP493_000426"
     CDS             78285..79304
                     /locus_tag="LP493_000426"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBL2132602.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            79347..80228
                     /gene="galU"
                     /locus_tag="LP493_000427"
     CDS             79347..80228
                     /gene="galU"
                     /locus_tag="LP493_000427"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBL2132603.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            80528..80905
                     /locus_tag="LP493_000428"
     CDS             80528..80905
                     /locus_tag="LP493_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132604.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            81511..82125
                     /locus_tag="LP493_000429"
     CDS             81511..82125
                     /locus_tag="LP493_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL2132605.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            82898..84637
                     /gene="yfcC"
                     /locus_tag="LP493_000430"
     CDS             82898..84637
                     /gene="yfcC"
                     /locus_tag="LP493_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBL2132606.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            84794..85978
                     /gene="iadA"
                     /locus_tag="LP493_000431"
     CDS             84794..85978
                     /gene="iadA"
                     /locus_tag="LP493_000431"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HBL2132607.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            86089..86292
                     /locus_tag="LP493_000432"
     CDS             86089..86292
                     /locus_tag="LP493_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBL2132608.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(86393..87055)
                     /locus_tag="LP493_000433"
     CDS             complement(86393..87055)
                     /locus_tag="LP493_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2132609.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(87068..88570)
                     /locus_tag="LP493_000434"
     CDS             complement(87068..88570)
                     /locus_tag="LP493_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2132610.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            89118..90797
                     /locus_tag="LP493_000435"
     CDS             89118..90797
                     /locus_tag="LP493_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBL2132611.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            90924..91403
                     /locus_tag="LP493_000436"
     CDS             90924..91403
                     /locus_tag="LP493_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HBL2132612.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            91622..92302
                     /locus_tag="LP493_000437"
     CDS             91622..92302
                     /locus_tag="LP493_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBL2132613.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            92310..93641
                     /locus_tag="LP493_000438"
     CDS             92310..93641
                     /locus_tag="LP493_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBL2132614.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            93656..94618
                     /locus_tag="LP493_000439"
     CDS             93656..94618
                     /locus_tag="LP493_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HBL2132615.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            94729..95067
                     /locus_tag="LP493_000440"
     CDS             94729..95067
                     /locus_tag="LP493_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HBL2132616.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            95146..95853
                     /locus_tag="LP493_000441"
     CDS             95146..95853
                     /locus_tag="LP493_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HBL2132617.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(95956..97437)
                     /locus_tag="LP493_000442"
     CDS             complement(95956..97437)
                     /locus_tag="LP493_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2132618.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLIKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            97746..98282
                     /locus_tag="LP493_000443"
     CDS             97746..98282
                     /locus_tag="LP493_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL2132619.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            98360..99730
                     /locus_tag="LP493_000444"
     CDS             98360..99730
                     /locus_tag="LP493_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HBL2132620.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            99797..100132
                     /locus_tag="LP493_000445"
     CDS             99797..100132
                     /locus_tag="LP493_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132621.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(100213..101070)
                     /locus_tag="LP493_000446"
     CDS             complement(100213..101070)
                     /locus_tag="LP493_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2132622.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            101177..101692
                     /gene="tadA"
                     /locus_tag="LP493_000447"
     CDS             101177..101692
                     /gene="tadA"
                     /locus_tag="LP493_000447"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HBL2132623.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            101715..101799
                     /gene="ffs"
                     /locus_tag="LP493_000448"
     ncRNA           101715..101799
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="LP493_000448"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            102009..103394
                     /locus_tag="LP493_000449"
     CDS             102009..103394
                     /locus_tag="LP493_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBL2132624.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            103431..104108
                     /locus_tag="LP493_000450"
     CDS             103431..104108
                     /locus_tag="LP493_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HBL2132625.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            104116..104880
                     /locus_tag="LP493_000451"
     CDS             104116..104880
                     /locus_tag="LP493_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HBL2132626.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            104882..105541
                     /locus_tag="LP493_000452"
     CDS             104882..105541
                     /locus_tag="LP493_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBL2132627.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(105571..106080)
                     /locus_tag="LP493_000453"
     CDS             complement(105571..106080)
                     /locus_tag="LP493_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HBL2132628.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(106192..107190)
                     /locus_tag="LP493_000454"
     CDS             complement(106192..107190)
                     /locus_tag="LP493_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBL2132629.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
BASE COUNT        35758 a        18471 c        22077 g        31068 t
ORIGIN      
        1 ttttgtttgg ctgttcttat tacttgatgc agaacagctt tttcacaacc tctttttata
       61 agagttttta ctcattaatt tacaaaaaac aagcaaaatg cgaattttct cacatttttt
      121 ttaacaaaat caaagttatt gcttgaaaga agaagaatcc atcgttaaaa taaagcttga
      181 cgtagagggg agcaagaaat atgaaagatt ttcaattggg ggctgccacc tatttaaaaa
      241 gtgtagccat tcgggtgaaa gaccgagata aaatgattaa tttttacaag aacgttgttg
      301 gctttgattt gaaaagagaa gaaaacgaat tagccatttt aggaacagaa gaagctggaa
      361 gtgaaatgtt gctgctggaa gaaagtccta gagcgaatga tcacatgggg gtgatcaaaa
      421 agctgaaccg tttttcattg attatcccta gcacagaaga aatggcagat atcctttgtc
      481 gtatccgtaa aatgaattat ccaatcaaag aagctttaga agatcatgga cgtatgggga
      541 ttttgctcgt agacccagaa gagaatgaat tggaaattta ccatgaagag aataagaacg
      601 accaaagaga aattccagaa acaatggatc aagaagcatt attaagaaaa tctgaagaaa
      661 aattcagtaa actatcaaca ggttcttatt ttgaaaaaat ccatttaaat gttactaact
      721 taacaaaaga acgccaattt cttaatcatg tacttggttt gaaggtacat aatgaagaag
      781 agggcatcca tgtattgaat gaaggagatt tccatgttgg tttgacagaa gctagcggag
      841 gcgcaattga tttgcctaca gatgaagtga ttggacttga ttttctgaaa ttcatgatcg
      901 atactgaaag catggaagga ctgattgctc acttgcagca actatcagtt gatttcttct
      961 tagacaaaaa gcacacagta ctcacaatct atgatgctat aggaatcgaa tggtggttcg
     1021 tcagtgagcc aaaagaaaag aataaaactg acattcgatg cgacgcttaa ctttttcttt
     1081 cttaacgatt gtcgcatgtc tcgtcatttt atgaacggtc atactatcgc ttattctaga
     1141 gatagaaaga gaaaatagta taccggggga aactgcgcgg tttttcgcgc agtttttttg
     1201 tgtaaaaaag gttgattcct catagattaa gctttaagct tggactgtaa gaatctgata
     1261 gaaaagcagg agaaaaagat gtatccacac acgaaacagc ttattttgaa aaagatggaa
     1321 gaaggatttt atccaggtgt agcagtcgcc ttcataaaag aaaatcaagt agaaacattt
     1381 acagccggct ttgcccaagt cgttcctgaa aagcagctga tgacagaaga tctgttgttt
     1441 gatgcagcct cactgacgaa agtcgttgca accacttcat tagttttacg tctattagaa
     1501 gatggaaaga tagaactcga tcaaccgctt cataaatatc ttcctgaatt tgaaaatcag
     1561 acaatcactt tgcgtcattt actgacacat acttctgata tcaaaacatg gataccaaac
     1621 agagataagc tatctcagga agaattgatc gccgcttatt tgaagctaga accaggtgag
     1681 caactaggaa aagaagtaaa atatacagat gccggtacga ttcttcttgg gttgatgcta
     1741 gaggaaattt accaagaaac tgcagtggaa atctttcaag aacaagtatt ggaaccatta
     1801 ggaatgatga acagcttatt tcttcctttt ccttccaaaa aaatcgttcc cacagaacaa
     1861 ctgccttcgg gtgaggtttt gcgtggacaa actcatgatc cgaaagcaag agttttggct
     1921 gaacatgcag gtaacgcggg tctctttatt gatttgaaag acagcattac ttttgtccaa
     1981 atgtatttga acaagggaaa aatccgtaat ggtcgttttt tagaagaaga gacgattgat
     2041 tctttactgc aagatcaaac accgaaaaaa aatggctatc gttctttagg atgggactta
     2101 aaaaaggatg tagaagacgg tcatgcgatt ctttttcata ctggttatac aggtacgttt
     2161 ttcttgattg atataaaaac acaagaagcg ttgatatttt tgtcaaatcg cgtacatcct
     2221 gtcgatcatc gtgcggagta tctcatatgt cgagatgaaa ttgttgaaaa ctttttgaaa
     2281 gagaaagcgg tattaccgaa ataatgctat aatagctatg aaaaatgaga ggagtttgaa
     2341 ttatgcagga acctatgttt ttaaaaccag tttttcaaga aaaaatttgg ggaggaagtc
     2401 gtttacgttc agtctttggt tttgatatcc ctaacgataa aatcggagaa gattgggcga
     2461 tcagtgcgca tcctcatggt gtcagtgtag tagaaaatgg cgaattcaaa gggaaaagat
     2521 tagatgaact atggtcagaa cacaaggaat tgtttggcca tccttcagaa ccagtgtttc
     2581 cattattgat caagatctta gacgcagaag atgatctatc tgtacaagta catccagatg
     2641 atgcctatgg gatgaaacat gaaggtgaat taggaaaaac tgaatgctgg tatatcatcg
     2701 atgctgaacc tggtgcagaa atcatctatg gtcatcatgc aaagacaaga gaagaactag
     2761 ctgagatgat caaagatggg cgctgggatg accttttgaa gaaagtacca gttaaaaaag
     2821 gtgatttctt ttatgtacca agcggaacga tccatgctat tggtaaagga atcatgattt
     2881 tagaaacaca gcaaagttct gacacgactt accgcgtgta tgactacgac agaaaagatg
     2941 cgcaaggaca aacaagagag ctgcatatcc aacaatcgat cgatgtaaca actgtccctg
     3001 cgaaaacacc agaattacaa atcaaagaag tccgaaaagg gaattcatcg atcgtcactt
     3061 atttagaaac tgagtttttc aatgtatatg agtgggatat taaaggaatc acatctttca
     3121 aaaaacaagc cccttataca ttgatgacgg taatcgaagg agcaggagac cttgtcgttg
     3181 acggaaaaac atatccatta gaaaaaggaa caagctgtat tattccaaat ggcgtttctg
     3241 agtgggcggt ccaaggtgaa ctagcaatca ttgcgtctga accaggcaaa tagttcccag
     3301 atagctgaaa gcagcagacg gtttttcgtt tgctgctttt tctacataaa atccgtccat
     3361 caataaatag aagtctggtg aaaaagatgg aatacaaatg gaaagcaaac aacagcagtc
     3421 gcgtgtctat gaaacaactg agaaaagctg gacatcactt aaatgaaatg atcatgccaa
     3481 atctaagtct gtttatcgct tggggaatct tgtcattagc aacaaaaggt gtgtctggcg
     3541 atttgcacac cacattagaa gaggtatgcc attggatgat ccagctgctt ttacccatct
     3601 tgatcagtta ttcaggcggg aaatcggtag ggggacaaaa aggggcagtc gccggtgcaa
     3661 ttgcttcttt agggttgatc gctcgttcca atgctccaca aatcgtagga gcgatgatta
     3721 tcgggccgct tgccggcatc gtatatgaac aatttgtttc tagattccat gtgaaattca
     3781 aggctggata tgaaatgctt gtcagcaacc tactagtagg actgactggt agcgttattt
     3841 gtataattgg aatcgttttt attgaaccag ttttaaatag tgttcacttg ttgctcgcct
     3901 ccgttgtgtc ttggctagtc acaatgaatc tgttaccact tgtcagtctg atcttagaac
     3961 ctctaaaagt actatttttc aataatgcaa tcaatcatgg tgtattgaca cctttaggaa
     4021 tcgaattctc acaaacagtc gggtactctt ccttattttt gatggaggca aatcctggac
     4081 ctggtttagg gatcttactt tctatccttt gttttgcaga aaaacaggaa aaagtaaatg
     4141 cgagtggagc attgatgatc catgcgattg gcgggattca cgaaatctat tttccatttg
     4201 tcttgctgcg accgtatcta tttttagctg taatggctgg tggggcaagc ggcacgttga
     4261 tatttcaatg gttagatacg ggattagctg cacctgtatc gcctgggtca ctactcgtga
     4321 tttttgccaa tgcgccttat ccacaactag ctggggtaag tatagggata gcaatcagta
     4381 catttgtgac cttcatttgt gcagcgatac tattgaaatt accaaataaa gaaaaagaga
     4441 acaaaacggt caaagaaagg ggagaaatct tggaaccatc tatcattcat tccgtcattt
     4501 ttgcttgcga ctcaggtatg ggatcaagtg ctatgggagc cgccctgctg aaaaagaaat
     4561 tagcagcaga aaaaatcgat ctttctgtcg gatacagctc tatctatgaa ttgaataacc
     4621 aagtaaatca gctggttatc gtgcaacatg aactagcggg tcttgcaaga gaaaaagtac
     4681 ctcaaagtca aatctatgta ctggatcact ttttggaaac agatatcttg ctgtcacgaa
     4741 taaaagaagc gatccaattt ccaaagcggg aagaaaaaaa agagatagca gatatcacag
     4801 aacaaaaaac gtcgcctgct aatattgtat ttttgtataa aaacaacaga cgcggctcac
     4861 aaactatggg catgacgatt ttaagtcaat tagcaaaaaa agcgaaaaaa cagtttgtta
     4921 tctcaaaaga atcaatagaa aaaatcaaaa tccaagaaga aacgatttat atcgcacaaa
     4981 gagaactagc tgtaactgaa cagctagaag aaaagatccc tcggctagtt ctagttgaac
     5041 attgggtagc tacgaatgaa tacgaaaaac tcgtgaaggg agaaatataa gatgtattta
     5101 tcgcccagag aaaaacaatt attagcagaa tttctcagta gcccgtcacc tgtatctatc
     5161 caaaaaatga tgaatttatt gaaggtcagt aaacggacta tttaccgcga attagataat
     5221 cttgaagtct cattgaaatc ggtaaatgct tctttgaaaa aagcagctag aggctcattt
     5281 gtcattgagg catcagaaga agtattagag caattaaaag aaaatacaga tgggaaaagt
     5341 aatgacttat ccactgctaa acgacaacac gcgattttag ccgagttgtt actgacgaca
     5401 gagccgttga gtcttgctca tttcatggaa tcatatcgca tcagtaatac cactttttat
     5461 gcagatatca aacagttgga agaaagtatt cgccaactgc ctttggaaat cattcggaac
     5521 cagggatacg agatcgaagg accggaaaaa taccgccggc ttctgacagc gaatgtatta
     5581 gaattagaaa tcaatgaata tgaacttttt catagtattt ctttcgatgc atcactgaat
     5641 tatttttttc gattcgttga tccgcaacat ctatctcttg cacgcaaagt aatcggggaa
     5701 gaattgatcc aaaaaaagac caatctaagt gatagaaagc ttgaacattt ggttttgatg
     5761 ctgacattga cgatggagcg tgtgacgaaa aatcatttac tgacaaatga gacatataat
     5821 agtctggcaa acaaagaatt actacagaca gctaaacgat tgttttcacg gatcgcttct
     5881 gagacaaaac aactttatcc agtaaatgag atcgtctttt ttgcaggatt attaaatgac
     5941 ttcacgaact catttgatca gaatttcttt gaagagacgt tcgatacaca gcttgcttat
     6001 ttagtaaaac aactgattca agaagtaagt gaagagacga atgtccattt ttatgaagat
     6061 gaaactttgt acaaaatgct gttgactcat ttatctggtg tgttttcaag agccgtttta
     6121 caagaagaga cactgaccaa tccgatttta gaaaaaatca tggttcaata cgaggaagtt
     6181 gcgaatgcaa tccgtaaagc agtagagcgg atttttcaag aaaaaaaatt atccgaagaa
     6241 gagatcgctt atatggtcct tcattttgcg aattcattgg aacgaagtcc gaaagaaagc
     6301 aatatcagta ttgcaggatt ttcgccaagt ggattagctt ctactagcat gttggaacta
     6361 cgattgaaaa ggtattttcc cttcatccaa caaattcatt tctatcggat tgctgattta
     6421 aaaaaaatcg atttacaaga agaatatgat gttgttattt ctacatctat tttaccagga
     6481 tacggtggaa aatatatttt agtctccccg ctactgctag aagatgaagt caagcagcta
     6541 aaagaagctt tttcgcatat tgagaagaaa aaaaggcaaa aaattacgta taacagcaat
     6601 aacgagtgga tgatagaaga tacttatgag gaaacaatgc atttcatgga tcaaatcaat
     6661 caattactcg gtcgtttttt tatccaagaa ctggataatc ctgagacgat ttccgaaacg
     6721 attcgcagct tatttcctta ttttcctgaa ggactagtaa cggatgaaga ggtggttcat
     6781 cgccggctgc ttaagcgata tgaacaagca cctatcggta ttcctcatac aaatatgggg
     6841 ttattccata catccagctc attgatttct aaaccgatct tttgtatttt caatttgaaa
     6901 catccgttga ccattgaagg gatggataga cagccagtcg atttgtcccg tatgttagtt
     6961 atgctggcgc cttcgccaat ccaagaaaaa gacgggattc ttttaggaaa gatcagtgga
     7021 gcaatcatca tgaatgactt gaacaccgag atcttccgct caggaaataa agaaatcgtt
     7081 tatcagttgt tagcgaaaat cctgattgaa gaaataaaga aatgaaggtg aaaagatgat
     7141 acagctacca gcagaaaaaa tattgctcga tcaatcctat caaaattgga aagaagcgtt
     7201 gaccgagatc ggccagtgga tgacccaaca agggggaatc aaaccggcat atatccaatc
     7261 aatgatcgaa agacaagaaa aagcgagtgt ctatatcggg aatttcgtag ccttgccaca
     7321 tgggactgac aaagatgaag aagtagtaga agaaggaatc tatttagtcc aagtgcctga
     7381 tggtgtggac tttggaacaa aagaggaacc aaaaatcgcg acactcttat ttgtagtggc
     7441 tttaaaaaaa gaacatcagt tagcggtgct ccaagattta gcctttttct gttcagacat
     7501 cgaccaagta atggcgctca gtgatgcgga aaccattgaa gaagtccaaa tgatttttga
     7561 acatggacat atataaccaa tgttcacagt aaaaaaagct gccttgcatc aagtaataac
     7621 ttcaaccaag ataaaaataa gaggagctat ttttgttggg aggttcttat tactgcggat
     7681 gcaagctttt gaaaactatt tattctagaa aaccgtttat ttgaaatagg ggacggtgac
     7741 aaggtttttg tcaccgcccc tattattttt gtgttttaat agctcttttt tatatagata
     7801 gtgcccatac ctatgaataa taaaacgata ctccatatac caagtgtcaa gataccattc
     7861 atgaaagtaa cctgttctga agctagtggc gagaaaatat ctcctcctat gatcacattt
     7921 tgaaaatcaa cataagaagt tggcaagtaa tgactgattg attctatcca tccaatcgaa
     7981 gaaaacaagc gatactctgc taagaaaaga caaagaagtg tacctaaaag attgactaga
     8041 gaatgttcaa ataaagcaga tagaagaaaa ctgattgtac ttaaaaagag cacccacaac
     8101 aacaggaaca gaaagctctg gaaaagatac tcatacatcg gcaggattcg tatctcctga
     8161 ccaatgatcg ttcctacagg ataacggaag tctcccaaac catttttgat tattactagt
     8221 atagagacga tcaaaaatgg catcacgaga cttagcatag ctgcaccata ataaatggta
     8281 aaacggatgc tatgtttctt taccatacta tccagtaata gattgactag agagattacc
     8341 tgctttcttt tttcataaga gatgatggaa gaaagaaaca aggcggttat acataaaatc
     8401 aaaaaactag aaatcattcc tgaaaaaata ttttcgtagt aatttgctaa agagagatgc
     8461 gctggcaagt caaaaataga atatctttgg atctgatgtt ctttcatata acggagcaac
     8521 tcgacacgtt tttgttgttc aatgattgga attccttgtc tttgaccaga aatcagtcga
     8581 tccagtatat ctttttcata atgataagtt gcttcgacca tttgctggac attccctgtg
     8641 ttttttgcat gtaagattgc ttcgatcagt ttgttgcttt tctctaaact ttccacaaat
     8701 tctttctcat tctcatcttc tttcaacgtt tcaatcaaac gttgcatctc ttcatagtta
     8761 tgattcagtt catcgaattc tgtataagca agtttatgat caaaaaaaag tgggaatgca
     8821 aagagcacga ccaacaatag aggaaataaa aagtttactt tgttttttag taagagattg
     8881 cgttcaaatg taagtaaaga catagttaca cctcatataa tttacgataa atagctaaaa
     8941 tctcttccat atttgaggat tctgtgacga tttctccatt ttttagaaaa catgctttag
     9001 aacaaatcga ttggatattc gcgatagcgt gggaagaaag aagaatcgtc ttcccctctt
     9061 tctgccattg tctgatgagg ctattcaaga tatcaatact tcctgggtct aatccgttca
     9121 acggttcatc gaataacatg acagatgaat cactgatcaa gtaagcagca agcaagacat
     9181 gttgtttcat tcctagagac atttttccaa tcggcaaagt aaggtactca gtcatcttca
     9241 atcgttggaa aacagtttgg cattctactt tgctctgcca atagtatttg atcaaagtca
     9301 aataatcaac agccgataga tagtcggata actgattcgt tgattctaga aaaaagaaag
     9361 accggcgata atctgtataa gcagtaggag agatgttgtg aagggacaat tgatcataag
     9421 ttgttggcag cagttgggca atgccattca gcaaagttgt tttgccaaat ccgttcgggg
     9481 caatcaaagc agctacttct cctgattcta ctaaaagatt caattgtcga atcacacgtt
     9541 ttttaccacg tttcatgttc atgtttttga tcagtaatgt catagatagg cctccaatat
     9601 aaaatttaat aacataatag aatggaaaac atctaaatta aatgctaaca aaagttattg
     9661 tttgcatatt ataaaaaaat taaaataaca gttttattta aaattgaagt tttctgatac
     9721 cgaaatcttt ttattttgct gacatactca aacctttggc acaaagtttc gtgccaaagt
     9781 acgactattt ctctttttag taagcggata caattagagt atcaaaagga gagagggaga
     9841 gacaaaatgg aacggacgat tcccaaaaac aacatttcgc taaaagcgag ggtacaaaaa
     9901 ttaggcagta ctttatcaag catggtcatg ccaaatattg gagcactgat tgcctggggt
     9961 gtattaacgg ctctatttat cccagatggt tatttaccaa atgaggcttt cgctaccatg
    10021 gtaagcccaa tgctaactta tctgattcct ttattgatcg gttatactgg cggaaaagta
    10081 attgctggtg accgcggatc agttgttggg gcaattgcaa cgatgggtgt gattgtcgga
    10141 acagatattc caatgatgct aggcgcgatg atcatgggac ctcttggtgg atatgccatc
    10201 aagaaatttg atcagctatt ccaaaaacgg atcaaatccg gttttgaaat gctagtcaat
    10261 aatttttcag caggtcttat cggttttgga ttagcgttat taggtttttc tgcgattggt
    10321 ccagttgtcg atgcattgac tcaagcaatg gcaaaaggtg tagagatcat tttatctgcc
    10381 catttgattc cattgacaag tatttttatt gaaccagcaa aaatcttatt tttgaataat
    10441 gcaatcaatc atgggatttt gacaccattg ggaactgaac aagtagcaga ggctggaaaa
    10501 tctattctat tcttgcttga agcaaatcct ggtccaggac ttggcgtatt acttgctttt
    10561 actttgtttg gcaaaggagc agcaaaatct tcagcaccag gagccatgat cattcacttt
    10621 ttaggcggga tccatgaaat ctattttcct tacgttatga tgaaaccgtt attattctta
    10681 tcagttatag gcggaggaat gtcaggaagt ttcattttcc aattgatgga tgctggacta
    10741 agagcgccag cttctccagg gtcgatcatt gcgattctag cgatgacacc gttcaattct
    10801 taccttcctg ttattttggg cgtgattgtt gccgcagctg tttcgtttgg tatttctgca
    10861 gtaattttga aagcggatgc gaaagataca aatgaagact tcgaaaaatc tgttcaagag
    10921 acaaaggcag ctaagcaagc ttccaaaggt gcccaaggta ttcctcaagg agctacattc
    10981 tctggcgtac aaaaaatcat ttttgcttgt gatgcaggaa tgggatcaag tgcgatgggc
    11041 gcttcgatct tgagaaaaaa agtacaggaa gcagacttgc ctcaaacggt gaccaatcaa
    11101 gcaatcagcc aactgacaga tgactcgaat acattgatcg ttactcaggt cgaactacaa
    11161 gaaagagcaa aacaaaaagc accgagcgcg cgttttgtct cagtagaaaa ctttttgaat
    11221 tcacctcgat atgatgaaat cattcaagaa ttaagcagca agcagaaaac atcagtttct
    11281 gaaattgaga atgagccagc agaagagttt ctttcagcaa acatcaaaca aatcaaagag
    11341 attctacttg tccacgatga tcgttccgga tcagcaacaa tggggatgac cgtgctcaaa
    11401 gatatattag acaagaacca tttaactatc ccgttaagaa aagtcaatat ccaagattta
    11461 aaagatgaac ctgattcact gatcgtagcc aaagaaagtt tagcggaaaa agtacagatg
    11521 gctgcacctc aatccattca tttatcagtc aacagcatgg tcaatccgca aaaatacgaa
    11581 tcgattgcac aatatttgaa acagacagct taagggagga aaacagcatg caaagtttgc
    11641 cattcgacat gatcgagctc aatcgatctt ttaaaaccaa agaagaagcg atccgctatt
    11701 gcggtcagat gcttgtagaa gcagggtgcg ttgatgagga atatatcgat gccatggtag
    11761 atagagacaa aatgttatct gtttatatgg ggaattttat cgcgattcct catggaacag
    11821 atgaagcaaa aaaatatgtg aaaaaatccg gcatctgtgt cgttcaagta ccagatggtg
    11881 tagattttgg taccgaagaa gaagaaaaga ttgcgactgt tttgttcggt attgcaggag
    11941 tcggagatga gcatttgcaa cttgtacagc aaatcgcact ttattgcagt gatatggaca
    12001 atgttgtcca gctagcagac gcgctcagca aagaagaagt aacggaaaat ctagcaattg
    12061 cttaaggaga gagaaaaatg agagcagtac attttggtgc aggaaatatc ggtcgaggat
    12121 ttattggaga ggttttggca gctaatggat ttgagattac tttcgtagat gtgaatcaca
    12181 cgatcattga tgctttaaat gaaagaaaag aatacgaaat cgaattagca gatgaatcaa
    12241 aagaaaaaat cactgtaaaa aatgtcaaag gaatcaacaa tcaaacaaat ccagaaaaag
    12301 taatccaaga aatcgctgaa gcagatttag ttactaccgc cattggcccg aatatcttac
    12361 cttttattgc tgagttgatt gcaaaaggta tccaagaaag agaaaaggaa ggaagcacaa
    12421 catctttaga tatcattgcc tgtgaaaata tgattggcgg ttcagcattt ctagaaaaag
    12481 aagtgtataa atatcttccg gaaacatcat ttactgacaa atatatcggc tttccaaatg
    12541 cagcagtcga tcgaatcgtc ccattacaac accatgaaga tcctttattc gtccaagtgg
    12601 aacctttcaa agaatgggtc attgacgata gccaaagaaa aaataaaaaa atccaattaa
    12661 aaggggtttt atatgtagat gatctagaac catatatcga acgcaaacta tttagtgtca
    12721 atactggtca tgcgactgtc gcttatacag gtgccttgtt aggttaccag accattgatg
    12781 aagcaatgca agatgcgtta gttgtggcac aattaaaatc agttttgcag gaaacaggaa
    12841 gtttgctgat tgccaaatgg gggtttgatg cagagcagca tcatgcgtat attgaaaaaa
    12901 tcattcatcg cttccaaaac aaaaatatct ctgatgcgat cacacgtgtc gctcggacac
    12961 cattacgtaa gttaggttat caagaaagat ttacacgtcc agtgagagaa ctacaagaac
    13021 ataacttgac ttgcccacat ttgacggcaa caatggggat tatttttaat tactatgatc
    13081 ctgaagatga acaaagccgt caattgcatg aaatgaagat ccatgaaaac ttggaacaat
    13141 tgattcaaga agtcacagga atcaatgatc cgaaaacaat cgggaatatc aagcaaaacg
    13201 tgaaccgtta tgccaagcaa gtcgcttaaa ataggatacg aaaaagggga atgtgacgaa
    13261 atttttgtca cattcccctt tttcgaataa ctaggctgtt tgtccttcaa gatagggcag
    13321 atccaattct ttaccgtaac gttgttctaa agctaggcgg atcaaacgag ctgccaggtt
    13381 ctcatttctt gcaaggatag gtccatggaa ataagaaccg aagacatttc ggtaaatgac
    13441 accttcagat tggtcttcac cattatttcc ttgaccttgt accactttcc ccaaaggtcg
    13501 ttcaccttca cctaagaaag tccgaccatt gtggttttca aatccataat aagtttcatt
    13561 gaattcttcg ttatggataa cgatatcacc gataaaccgg ttattttcct gacttaacgt
    13621 gtagtgatcc agtgcactga ttccttggat cttttctcca ttagctccca tgtagtagtg
    13681 acctagcaat tggtagccac cacaaatggc taacatgacg ccatcatttt cgatatagtt
    13741 gatcaaagaa tctttctttt tctggatgtc ttttgaaatg attaattgct caaagtcttg
    13801 accaccgcca aagaaaacca agtcatattt atcagcatca aaaggttcat gtatactaac
    13861 gatctccgta tggcaagaaa cccccatttt ttctgctata tatttcaaca tcaaaaggtt
    13921 tccgttatca ccatatgtgt tcatcaaatt tccataaagg tgggcgatat tgagttcata
    13981 attagccacg gttcattcct cctttgataa atccttgagc agctagttct ttacgaagct
    14041 gcaatacagc agtgtaagta gctaaaatat agacatgctc agttggcaat tctttgattt
    14101 tttcgattac ttctggtaat tcttttgttt ctgtcaattt attttctgga atcccggcaa
    14161 cttttagacg taaagtcata tctgtatgac ggtctcctcc agaaataaca gctgggatat
    14221 ccatatcggc aaagttttca aaattaccat cccaaatcca gctgacatcg attccgtctg
    14281 cgtaattggc atttaataaa gccactaaag aaaatggata aggagctaga ccaatcatat
    14341 cgattacttg attgatacct acaggatttt tgacaagtac taatgtacat tttttcccat
    14401 tgatattgat gacttcttgt cggccgaata ctttctcgtc atatcctaaa ccttgtttga
    14461 ttttatcagg atcgacattg aagtactctg ccactgcagt agctgctaaa gcattgtaga
    14521 cattatacat accgccaact tcgattccgt attcatgacc atcgatcacg aaatctgctg
    14581 acacattgtc catccgtacc atatcagtta atcgataatc caattcagga cgtttgaagt
    14641 cacaatttgg acagtaatat ttccctaagt ttgcataagt gatcatttta taatgcaaga
    14701 tgtgatgaca atttggacat aagacaccgt ctgtattgta atgagccatt tgttcacgat
    14761 cttcttcatg gtcaaagcca taatattttc taggattgac tgtttcgata gaattgaaga
    14821 ttggtgaatc accgttactg ataatcgttg catttggtga ctttgcggca ccgtctacaa
    14881 tcattttata ggtcgtatag atttctccat accgatccat ttgatcacgg aaaatatttg
    14941 taaataagaa cagttctggt ttcatatatt ctgtgacttt gctcaaactt gcttcatcta
    15001 tttctaggac agcaaacttt ttctgtcctt tttttggttt tgcctgcaag aaagtcgata
    15061 caattccctg taccatattc gcaccagtag ggttggttag aacttcatcg aattgctggc
    15121 gcaaaatatt gactgttaaa gcggtagtca atgttttacc gtttgttccg gtgacaacga
    15181 cgacttggta gtcttttgcc aaactatcta gtatatgtgg atcgactttc agcgctagtt
    15241 tacctggtaa acttgatccg cctttaaaaa aagtttttaa tgcccattgc gacgtttttc
    15301 caactgcaat cgcaaaatga ctgcgtattc ccattatgta acctccaaaa acgatttgct
    15361 gacgaataaa ttcaactaat cataccatat gttgaaaaaa aggttaaatt gcttttctta
    15421 ttcttaagaa aaggttacgg ctgaaagtgc atgaaatcgg acaaaatcgc atgatttaac
    15481 aaaaaaacag cttgaaacaa aatgattgtt tcaagctgct gtgattttat tattccctct
    15541 tacctatatt cccattttaa ccgataataa ttttctcgct tggatattca tagcctagat
    15601 ctcgtgtttc ttttggcacg aataacatca atgtatatag cattccgatc cgcccaataa
    15661 acatcagtgt agcaatcgtg attttgccca caacagacaa gtctccggta atccctaaag
    15721 ataaaccagt tgttccaaac gcagaagtta cttcgatgat gatcgagatc agcgtttgtt
    15781 cttctgtagc agataaaaaa acgatacaaa agaaacacat accaagagaa agcataaaga
    15841 caacgactga ttttcgcaca tcatcttgat cgattctccg tccaaaaata ttgatgttat
    15901 cttcactttt gaggaaggaa tatagataca aaccgatgat tgctacagta gttgttcgaa
    15961 tcccgccgcc tacagaacta ggactgcatc cgataaacat cagtaaagaa aaaatgatca
    16021 gtgttgtgat ttgaaaatca cccaaatcgt gaatctgcag accagcatta cgagtcgtaa
    16081 tcgaataaaa catcgaattg atccatttga cactcatatt ggaatcttgg aataaatggt
    16141 ccttttccaa tagataaatc aagacagttc ccgaaacaaa caagataaca aaagctaaca
    16201 cagctaattt ggtaaacaag gaaaaacgaa acggaagctt cgcattggaa cgtttgtata
    16261 atagccattc ccggcactcc atcaatacag gaaaaccaat tcctccgaca aaaatcaaaa
    16321 acatgatcag gatcaagaaa aaatagtcat gtgcaaaggg cttgatggaa tccccagtga
    16381 cgtcaaaccc agagttcgtg acagccgata tcgcctgata aaaaccgtaa aaaacggcat
    16441 cacgccaacg atcaaaatag cctctgtaat aaaaataaat agaaaagaat gtcccaaaaa
    16501 gtaattgaaa ccagattaaa atagcaaaag tgatccgaat cagtcggacg ataccagaca
    16561 aacgcggttg attcatatcc gtcatgatca gctgtcgctg tttcagtgtg atccgtcgtt
    16621 tagaaaaaat gacaaaagca gtagaaatca tcatgatccc caaaccacca acttgaaata
    16681 atatttccag cagtataata ccgttatcat tgaacacaga attgatatca aaagtcgata
    16741 gtccagtcac actcactgta ctgattgcca tgaacagcat gtccacaaaa gaaacatggc
    16801 tatctggttc gcgaaaaatc ggcatataaa atagaacgag tgataagacc gtcatcaata
    16861 tataataaaa aacgatgatt tggatcgatg agaaatgatt ggcagcaaac ttctgtcctc
    16921 gccgctgcag ccttcgaaag aataaatcaa catgcacagt actatcctcc tgacaatagt
    16981 cgtttctacc agtatacaag gggaattagg aatactcaaa gaaattatca aacagataac
    17041 aatacagctt tcgattaaaa tagaaatggc ttataataag gaaaatccta gaaaaaagaa
    17101 ggaggaggaa taacaaattg attaatgctc aacaaatcgt agaaaaaatg aaaaatcaaa
    17161 aaataaatta tgatacagtt ctgaaaaaaa tgatcatgca atgggagaaa gaagaagtaa
    17221 agcctaagat attaatacat acatgctgtg ctccttgcag tacgcacaca ttggaattca
    17281 tgtctcaata tgcagagatc acgttatttt tttcaaattc gaatattcat cctaaaagtg
    17341 agtatttgcg aagattacat gaacaaaaac gatttgtaga ccaatttaat gagaaaactg
    17401 accatcatgt tgcgctaatc gttgatgaat accgtccaaa tgaattcacc aaaatggttt
    17461 taacaaacca tcttgaaaac gaaaaagaag gtggtgctcg ctgcagtgca tgcttcaata
    17521 tgcgattaga tcttgttgcg caaaaagcgc aagaactagg atacgattac tttggaagtg
    17581 ccctgaccat ctcgccaaag aaaaatgcag ctttgatcaa tcagatcgga atggatatcc
    17641 aaaagattta cgggacacaa tacttgccaa gtgatttcaa gaaaaacaaa ggctatgaac
    17701 gctctttgca aatgtgcaaa gagtatgata tttatcgcca atgttattgt ggttgcgtgt
    17761 tcgctgccaa gcagcaagga tgcgatctga aagaaatcaa tcgggaagca aaagcttact
    17821 taaaaacatc aaccgtagtt tttgaggaaa attaaagaaa tctttcggaa aaacgtaaga
    17881 aaaaaataaa gaatttatgg tagaaataag gtagactgta taatttgtcc gtagtaaagt
    17941 aaggaaacaa gaataaattt caatgaagga agagataaga tgcgaaaagt agcacctatt
    18001 ttgaagccaa tcgctgtatt aacaatctcg acgattgtcg cgactactac aggtattgtg
    18061 aatagttcca gctaccgtgc accaagttca agttctagta ctgtagaaga aacaacacca
    18121 actacttcag tctcgacatc tgaaccaaca acaacggaaa gtttgaatga aaccactacg
    18181 acaagtacat gggacgatac aacaactagt tcgtcgtatg atgagacata tacaactgac
    18241 agctcaagcg aaacaagtaa tacggtacca gatggcactc catcggattc aaccaatcca
    18301 agtacaagtc cggatacaag tgctagctcc gaaacgatac caagcagtac gactgtagat
    18361 gataacacgc aaaatgatga tgcagcacgt acagcacagc aaaaccaaga ttcaggaaat
    18421 acccaaacgt ataaccagca agcaggtgat tctcaatgac atttttacta gaccttatca
    18481 acggggtgca taaattcctt ggctatttag acatcagtcc taaatatctt aaccgtggat
    18541 atacgatttt aagtgtgatt cccacgcttt atttattgag aattgtttat ggactttggc
    18601 aaaaccaaaa ctatcttcaa tttttcttat atggacttgc atttctagtg cttgtttatt
    18661 ttactgtttt aaatgtattt tattactttt tagataaaaa cacgaaagcc gatgtcactc
    18721 agctttttgt gaagtattta cctgatgaag cgttcaacat ccagacagaa gaatcgatag
    18781 ataatggaaa ttcgatcgat aaagtgaata cacaagaggt catggtttct tatgacgaag
    18841 attatcaatt gaaattagcc gagaatatgc ggtatttgat tggaaatggt gagatcaaaa
    18901 caaatgaact cggtcgcatg gatggatttc tggtcgatag aaatacattg tatccttatt
    18961 actatgtcaa gaaaacagga gagaaagagt atgttctaaa tattggacga agctactcgg
    19021 acatggaaaa agtagggacc attcgacttg actcaacaga agacacattg gaacctgtcg
    19081 gattgttcat cgtcggcggt gattttgtca aagacgggtt acgctatcat gagccttatc
    19141 gtctgaaatt gattgcaaaa aaggcacagt cgcaggaaga accagtggtt tatagtcgta
    19201 gccaaagaag aagacattca taatgtgatg aaacgccgtg tatcagtggt tgcgataaaa
    19261 acgtttattc ggaataaggg ggatgtgaca cgtcttttgt cacgttcctt ttttatataa
    19321 cgagaaagat aagacgaaca catcacttat tctttccttt catttataaa cattgtagaa
    19381 taaagaaagt acaacgaagt attgtgaaaa aacgtaataa ataacgagga aaatacaagt
    19441 aggaggtaag ctgtgaaaga atttttgaaa aattggggga ttttgatcct tgtattagcg
    19501 gctattttat tagctagagt gtacgtgttt acaccagtta ctgtaaacgg gcattcgatg
    19561 gaccctacat taagtgatgg acaacgattg atttcatcta agatctcaaa ctatgaacga
    19621 atggatatta ttactacaaa ggaaccgggg gatgaagaac ggatgattgt taaacggatc
    19681 atcggtatgc ctggagatac agtcaagatg gaaaatgacc agttgaccat taatggcaaa
    19741 aagtatgatg aaccttatct ggatgagttc aaaaaagaat tttcagaaga taagttacaa
    19801 ggagaatatg cttatagctc aggattccaa gcacaagcag aaagttcatc cacctttacg
    19861 agtgactttg aatatactgt gccaaaagga aagtatcttg ttctaggcga taaccgcttg
    19921 atttcaaaag acagccgaat gtttgggtta gtcgacaaag atatgatcca aggaaaagtt
    19981 gttttccgtt attggcctct ttcagaaatt aaaatcatgt gatgaaaaaa taaaaagaag
    20041 ctgtgacatg ttttttgtca cagcttcttt ttccgaaaat tccttcttat ttcttggagt
    20101 tgctcacttt ttttgcaatc tcattttaag ctttttggct gatggataag aaaagcgaag
    20161 cgtttttgtt cataaatagc ttttccccac gatggaaggt atgactagta gcagagacaa
    20221 agcccgtttt ttccaatcga ttattcaatt cttcttggct aaagccatta tggactttcg
    20281 gatgactaat ttgttcattc ttgtcaaagt ctacgatgat caattgaccg ccaggagcta
    20341 aaatttcata aagttttgta agaatattct ccgtatcagg aatgtgtaaa agtacaagtg
    20401 atagaaggat gagattagct tggacagcag gaaattcgac agaagcatca gcgtggatcg
    20461 ttcggacatt tttcagatct gctgcttgga tcttttcttc tgccattttc agcatagttt
    20521 ctgaagcatc ggcaatgatc agttctttga atctttccgc aagcggtaaa ctaacaagcc
    20581 cagttccgcc tccgtaatcc agcaggactt tttggtggct gtcgcgcggt agataagtag
    20641 ttagttcttc gcgaataatc ttggctaatg cttgacggtc aggggaatca taatggttag
    20701 cgatggaatc aaaaatattt tttgtcatca aatagctcct tacgtaaaac tttgaaattt
    20761 taacttatta tagcacgtga aaagaaagaa agcatgctat actcaattca aaaagggaga
    20821 atctagaaag aatatgccga tatcgtttgt aaaagataga gaggaaaaag gaaagtgtgt
    20881 ccgagaaata ttactagact tgcctgagtg gtttgggctt cctgaatcaa cggaaaaata
    20941 tatcgaggaa tcaagtaaac tacctttatg gtgtgaaaaa agaaaagaag aatatttagg
    21001 ctttatcact ctttcacaga caagtgaaga tactgccgaa atctattcta ttgtatggga
    21061 ataaaaaaag actatcatca ccaaggatta ggaacaaaac tttttaaaga agcagaaggt
    21121 tacgcagcaa aacattacaa atatttgcaa gtgaagactg tagacgaggg gcactactct
    21181 atatatgatc aaactatttg tttctacgaa tcattaggat tttcaaggtt ggaagttttt
    21241 ccaaatttat gggatgaatg gaacccatgt ttagttcttg tcaaaaaatt ggaacaaaag
    21301 tgagcaatag atttaatact aatctgtgct tgatgaaaat tctcactgta aaaaatgctg
    21361 aaaatcaagt ataataccat aggaacaaac tggaaggtga aaaagagcat ggcacaacta
    21421 ttttttaagt atggcgcaat gaatagcggc aagacgatcg agatcctaaa agtcgcacat
    21481 aattatgaag aacaaaataa gccagttgtc ttaatgacaa gcggtattga tacaagagat
    21541 ggtttaggcg ttgtttcaag ccgaatcgga ctgaaacgta atgcgatgcc gatatttgaa
    21601 gaaacagacg tatttgacgt aattcagaaa atggaaagca aaccctattg tgtgctgatc
    21661 gatgaagcgc aattcttaaa aaagaaacat gtcattgctt ttacgagaat tgtggacgaa
    21721 ttggatattc cggttatggc atttggtttg aaaaatgatt ttcgaaacga gttatttgaa
    21781 ggatcaaaat atttattgct ttatgcagac aaaatcgaag aaatgaaaac aatctgttgg
    21841 ttctgccaca aaaaagcaat catgaattta cattatattg atggaaaccc tgtttatgaa
    21901 ggcgatcaag tgcaaattgg cggaaatgaa gcttattacc ccgtttgtcg aaaacattac
    21961 tttcacccat caatgattac agaaggagaa taagcatgta cgatcaatta caagcaattg
    22021 aagaccgtta tgaagagctt ggagaacttt taagtgaccc agaagtgatt tctgatacaa
    22081 agcgttttat gcagctttca aaagaagaag caaacacgcg cgaaacagtc gaagtttatc
    22141 gtcgttataa agaagtagta caaggaatca ccgatacaga agaactgctt ggtgaaaaac
    22201 tggatgatga aatggctgaa ctagcaaaag aagaattatc tgaattaaaa aaagaaaaag
    22261 aagtcttaga agaaaaaatc aagatcttgc ttttaccaaa agatccaaat gacgataaaa
    22321 atatcatcat ggaaatccgt ggagcagcag gcggagacga agcagcatta ttcgctggcg
    22381 atcttttcaa tatgtaccaa aagtatgctg aagcacaagg ctggaaaaca gaagtgatgg
    22441 aagctaacgt taccggaatc ggtggatata aagaagtgat catgatgatc accggagaca
    22501 acgtatattc gaaattaaaa tatgaaagtg gtgcgcaccg cgtccagcgt gttccttcaa
    22561 ctgaatcgca agggcgtatc catacttcca ccgcaacagt tgtcgtgatg ccagaagctg
    22621 aagaagtaga gatcgatatt gaagacaaag atatccgtac agatatctat catgcttcag
    22681 gtgctggcgg acagcacgtc aataaaacag catctgctgt acgtttgact cacttaccaa
    22741 cagggatcgt tgttgctatg caagatgaac gttctcaaat caagaaccgt gaaaaagcaa
    22801 tgaaaatctt gcgtgctcgt gtgtacgata agatccagca agaagcacaa agcgagtatg
    22861 atgccaatcg aaaatcagca gtcggaactg gggatcgttc agaacggatc cggacgtata
    22921 atttcccgca aaatcgtgtg actgatcatc gtatcggatt aactatccaa aaattagatc
    22981 agattttagc agggaaatta gatgagatcg ttgatgcatt gatcatgtat gatcaaacat
    23041 caaaactgga agctatgcaa aatgggtaaa atgacctatc gagaagtcct gtcacgggct
    23101 tcttcttttt tagaggatca tgggaaagaa gcatatagta tccaattttt atttttggaa
    23161 cgaaaacaat ggaaaaaact tgattggctc cttcatatga acgaagagat ttcagaagaa
    23221 gaacagcggt tgatcgaaac cgatctgcga cttctgcttg cagatcatcc acctcagtat
    23281 ttgctaggat atgcagattt ttatgatcat cggttaaagg taactgaagc aacactgatc
    23341 cctcgaccag aaacagagga gttagtcgaa tggtgtttag acgagacgcc tggtgtaccg
    23401 ttagaagtga tagatattgg gacagggact ggagcaattg ctattagttt gaaagcagca
    23461 agaaaaaatt ggcatatatc tgctgtggat ctttcagaag aagcattaga agtagcgaaa
    23521 gaaaatgctc agaaagaagg aacgaaaatc agtttttatc atggagatac attaggacca
    23581 gtaatggatc agcaatttga tgtgattatt tctaatccgc cgtacatcag tcggaatgaa
    23641 tgggaactga tggatgaaag tgtccggtca ttcgaaccta aaatggccct ttttgctgag
    23701 aacgatggat tagctattta tgaaaaaata gcagttgaag caccaagcgt actaaaatca
    23761 aatggaaaga tttttttaga aatcggattt cgccaaggtg aagcagtaaa aaaaatattt
    23821 cagcaagcat ttccagataa aaaagtggcg ataaaaaagg atctttttgg caatgaacga
    23881 atgatccaag tttatggttg aagttgtgga tgaaaaattt tttatttgtt tttttattat
    23941 aaaaaaacac ttatttgaca aggatgtaaa cgactttttg gtttatcaac aagtttatcc
    24001 actattgaca aatagattat ccacaaacag tggaaaactt gaggataaac tcagacaaaa
    24061 taagaatgta tgaaaaaggg gttgtggata aactgtggaa acgaaacgat atgatgaaac
    24121 agaattgcaa gaggcagccg aagcactgaa agaaggagaa cttgttgctt ttcctaccga
    24181 aacagtatac ggattgggcg ccaacgctct tttaccaaac gctgtcaaga aagtgttttc
    24241 tgtaaaaggg agaccgcaag ataatccatt aatcgtccat gtcgcctctt ttgaacaagt
    24301 aaaagagtat gtggacaact ttcatccggc agcagagaag attgtgaaga acttctggcc
    24361 tggaccatta actttgatat ttaagatcaa aaaagacact ttgccctcag ttgtgacggg
    24421 aggattatcc acagctgcat ttcgtatacc ggataacaaa aaaacactag aagtaatcga
    24481 actttccggt gttccgcttg tcggtccaag tgcaaatacg tcgggaaaac caagtccaac
    24541 gactgcagat catgtatatc atgatctaca aggaaaaatt accgggatta ttgatgatgg
    24601 agctacgcga attggtgtag aatccactgt tcttgattta agtgatccaa cagccatgcc
    24661 tatgatttta cgaccaggtg cagtaacgaa agaacaaatc gaagcagtca tcgaatctcc
    24721 tgttgctatt gatcagcatc ttgtaaaaga aaatgaaaca ccaaaagccc ctgggatgaa
    24781 atacaaacac tactcacccg atacacgtgt tctgatggtc agagatggcg attggtcaac
    24841 tgcagttcaa tgggcaaaaa ataagaagat ccgtgcaggt gtcatagcaa gccccgaaat
    24901 tgcggatcaa gtgcggacag atactgcagc tgtttatatg tataacgaca actcagtaga
    24961 agcggcggct aaaggattgt ttgcaggtct aagaggatta gatgaaccaa cacttggatt
    25021 agatttgatt tttgtacaag tgtatccaga aactggattg gggaatgctt acatgaatcg
    25081 cttgaaaaaa gcagcaggac aaaattattt tgaaaaatga tcaattggtt attgtcgcat
    25141 tcttttagta tgatacaatg ctatcaagta aatcttctat cagtgaacga aaaactaagc
    25201 gtaactaatc gtaatagaag agatacgaat atttggcaat ttgtttttga tgggaaaaat
    25261 aaaattgtag gaaaataaaa ttgtaggaaa ataaaaagga gctgttgttt gtggtagatt
    25321 acaaaacgtt tgaccctgat ctttgggctg cgatcgccaa agaagaagaa agacaagaac
    25381 ataatttgga gctgattgcc tctgaaaact ttgtctccga agcagtgatg gctgcacaag
    25441 gaagtatctt gacaaataaa tacgcagaag gttatccagg gcatcgctat tatggtgggt
    25501 gtgaatttgt cgatatcgtt gaaaatttag cgattgaccg tgcaaaagaa ttattcggag
    25561 cgaaatttgc gaacgtccag cctcactccg gctctcaagc caacacggct gcttatctcg
    25621 ctttggtaga accaggggac acgatcttag gaatggatct ttccgcaggc ggacatctaa
    25681 cacatggatc accagtcaac ttcagtggca aaacctatca ctttgttgct tacggtgttg
    25741 atccgacaac agaagttatt gattataatg tggtacgtat tttagctaga aaacatcaac
    25801 caaaattgat cgtagcaggt gccagtgctt acggacgaac gatcgacttt gcgaaattca
    25861 gagaaatcgc agatgaagta ggcgcaaaac tgatggtaga tatggcacat atcgcaggat
    25921 tagtagcagc aggacttcat cctaatccag ttccttatgc agatatcaca acgactacca
    25981 ctcataaaac attgcgtggc cctcgaggcg gcatgatttt gacaaacgat gaagcattag
    26041 caaaaaaaat aaatagtgcg gtatttcctg gtattcaagg cggccctcta gagcatgtga
    26101 ttgcgggtaa agcagtagca ttcaaagaag cattagatcc tgcatttaaa gaatatagtg
    26161 aacaaatcat cgccaatgca aaagcaatgg tcaaagtttt caatcaagca attggaacca
    26221 gagtcatttc aggggcgaca gataatcatc tgatgttgat cgatgttcgc gagttaggta
    26281 taaatggaaa agaagcagag agcattttgg acagtgtgaa tatcactgta aataaaaact
    26341 cgattccttt tgaaacacta agtccattca aaacaagcgg tattcgaatc ggcacgccag
    26401 caatcactac tcgcgggttc aaagaagaag atgctgtaaa agtggctgaa ctagttgtca
    26461 aagcattaca agcaaaagat gataacgctc aactagacga agtcaaaaca ggtgtacgcg
    26521 aattaactga aaaatttccg ttgcataaaa aataaaaatt taaattccat tagtaaacag
    26581 aaaagttcaa tgttgggctt ttctgtttat tttttgggaa aacggattct ttgacaatat
    26641 cggtgatgct ctctagtata tgaggtgtaa ttttagtctt cacactaaat ctcagggagg
    26701 aaaagtcatg actgatcgta tctcgttaga aaaggaagca gtagcattca gtgatgcaaa
    26761 tgcgcctcat ccgcgtatct atgaactagc accggaagaa ggaagagttt tactagaaga
    26821 agtacaagaa tcacctgtga acaaatattc cgtcgatatt gaagacttga tggtggatac
    26881 tggcgaatgg ggaaaactca atattcgtct cgtacgacca gaagggaata tggataaatt
    26941 accagttatt ttttatattc atggagcagg ctgggttttt ggcagtgctc aaacccatga
    27001 taaattgatc agagaacttg cggttcgtac gaattccgtc gttgtctttc cagaatatag
    27061 tcgatcacca gaagcaaaat atccaacagc aattgaacaa aattatgctg tgttgcaaca
    27121 gctgaataaa ttagccaagt caaaaaatct ggatctcgag aatctaatcg ttgcaggaga
    27181 ttcagtaggt ggtaacatgg ctacagtcat gacgatctta acaaaagaac gaaagggcct
    27241 cccaatatcc aagcaattgc tgtattatcc agtcacaaac gctgattttg atacagattc
    27301 ctatcatgaa ttcggagaaa actatttttt gacaagagaa ggaatgatgt ggttttggga
    27361 ccaatatacg acgaatgaag aagagcgtgc tgaaatcaca gcttcgcctt tgagagcaaa
    27421 tataaatgaa ctaaatgatc ttccttcagc aatgatttta acgggagaag cggatgtatt
    27481 aagagatgaa ggtgaggctt atgcgcgcaa acttcgtgat gcaggggttc ctgttacaca
    27541 agtacgcttc caaggaatca tccatgattt tgtcatggta aatgctatgg atcagacaaa
    27601 ggcaacgcgt gcagcaatgg cattatctac ttcttggatc aagaaaaaag aataagcttt
    27661 gcttgtccgc aggaaaactt cttttcaaaa acggattttc ttaggaaaaa tggcgagttt
    27721 gactagtcaa tcacttgatt ttgttttaca attaaaaaga aacgacagaa caaaggagag
    27781 cttaaaaaat gggcaaattt caagtgatcg atcatccatt gattcaacac aaactaacta
    27841 ttattcggga caaaaactgc ggaacaaagg tttttcgtga agtagtcgat gaaatcgcta
    27901 tgttgatggc atatgaagta tcacgggata tgccattgga agacatcgtg atcgaaacac
    27961 cgatcactga aacaacacaa aaaacgttgt ctggtaaaaa agtagcgatt attccaatct
    28021 tgcgcgcagg tattggaatg gttgacggta tcttggaatt gattccagct gctaaagtgg
    28081 gacatatcgg tctttatcga gatgaagaaa cattggaacc acatgaatat ttcgtcaaac
    28141 ttccagaaga cattgatgca cgtcagttgt ttgtagtaga tccaatgttg gcaacaggcg
    28201 gatcagcaat catggcaatc gatgcattga aagaacgtgg cgcgtcgaac attaaatttg
    28261 tttgtttggt agcagcacct gagggagtaa aagctttgca agaagcgcat cctgatattg
    28321 acatctatac agcttctcta gatgaaaaat tgaatgaaca tggttatatc gttcctggac
    28381 taggggatgc gggtgaccgt ttgtttggta caaaataagt aaatacgaaa aagggtgtga
    28441 cacaactttt gtcacatcct tttttggtca tttttaacgt ttgatgcaga acagcttttt
    28501 cacagctttc gtttgcatat aaaaaaacca tcccaaaaat gcagagatgg tcaaattcaa
    28561 atctttttta gttctttgta gttaacgatt actacaccct tactttgcgt catcaagttc
    28621 gcattttctg cagtttcatc aatctcaaca acagcggaat ttttcaattg ctttgaaatc
    28681 gttccagttt gcgacttgcc gtgaattgtg aacattacgt gagtattgat cttgaatttt
    28741 tcaccaattt ccgatggtac gatagttgta tcaaattttc caaaagttgc cattttcata
    28801 aaacctgcct ttcacatcaa ttataccacg ttttatgaaa aatatcatga aattaaacta
    28861 attttccatc ggactcttta caatcagcca aatagagtat ataatttctt ttggataagg
    28921 ccagcttagc tcagttggta gagcaacgca ctcgtaacgc gtaggtcgta ggttcgatcc
    28981 ctatagctgg cattaaaaga gaagacagat atatcaagga tttttaatcc attgatacat
    29041 ctgtcttttt gtttaaagga aataaagtat gctttcttag caatagagca tgtattattt
    29101 ctataaaaat ttaggagaat aaaacgacta gcaatatagc tgtgaaatca aatatcacat
    29161 gaactgccca acttgtaatg atcgagttgc ttttaatggc agcttggttg aataacaatc
    29221 ttgccacccc ttgtatcaaa aggatgtgtg ctacagtgtg taaaatattt ccattatcat
    29281 aagtactgta atggataaat ccaaagatga ttgctgacaa gaaactagcg acaggaatgc
    29341 tgaacttact agaaaaaata gcgagaaaat acactgagaa caattcttct ccaagtatca
    29401 tgataggcaa aataataaat aataacgggc tgaaagcctc atttattgga ttgcctgtta
    29461 aaccccattt caaaatttgt tgcaaaaata ccgagactgc ggcactgatt actacattga
    29521 taaaaaaata tttggctata tttttgacag gagcgacagg tttcgagaac atttttttcg
    29581 tatctttttt accaaaaaca agtgtaaatg ctataaatcc agtgatagtt aaagaaaaaa
    29641 tgctaataat ggatggcgca aatagcaacc ctaacaaacc gagtacaacg acaatagtgc
    29701 ccaatatccc ttttttaagt tctatttttt ttcctaaaat gttattcatg ataataactc
    29761 ctactattca gtttttgaag atagagtcag tatacatgaa gagttaaaat aggcaatgtt
    29821 tttttatgga tatttgtatt gctaaaaatt tatcttatat attcattttg attatactac
    29881 ttttatttgt aaaaattttc tagcaaaacc aagtgcttgc aactgattaa gcgtacaatt
    29941 ttttagatgt tccgagcgta cttcaatcat ttcaaaggag ttgctactta aatcgatatt
    30001 ttttaaatca gtatcaaaaa agctagcatt ttctaaatca ttagtagaaa acattatttt
    30061 agtgagggaa cagtctacaa aatctgcgct tgataagaca gagtgctcaa aggtactttc
    30121 ttttatgttt gaaccagata aatttacata gtccatttta caattctcga ataacgtgtt
    30181 cccaatataa ctttccatca atttagtacc tgttaattta caattgacaa atttcacgcg
    30241 atgcaacatg ctttttgtca atatacagcc tgaaaaatca cagttttcga atatacagtc
    30301 ggtaatctcc attctttgaa aatcattgga agcaaaaaat gcatacttga aaatagattt
    30361 gtaaataatt ggatggcaga ttatttggtt ttcgatgacc tctttttgtg aaaggatatt
    30421 atacagttca aaatcttcgt tttcatagat atgaaaaaag gatcctttat tcaagcttgc
    30481 ttcattaact ttaggaaaaa tcatatttaa ttacctccat tttcataaag tcatattaac
    30541 aaaagctaaa ccaacttaca ttagcagaaa atgagatagg ttttcgcctt tttcgataac
    30601 gatagtgtcg ctatctcttg aaacgttctt agaattgccc tgagagacac aaattaggcg
    30661 taattctaat aaaaatctta gaataaaaat ttttactgat ttaatttaga atgtttttaa
    30721 aataaaaatc gttgccataa cagtgtattg aaaggtttta acaatccagt aatgatttaa
    30781 aaaaatctag atgtagcgta tactttgttt atagaatgta gtgggaagaa atatattttt
    30841 gggaggaaat cgtgatgtct aaaagtgaag aaatagaaaa catggtacta aaattatatg
    30901 atctcgtttt aaatccagag atcaaagaaa aggaacgtat acttttgata gacgcaaaga
    30961 caggcttaga aaaaggtcag tattatccta aagtcataaa taatttggaa cgtagtttac
    31021 gtccgttagc aatcagggga gaattgtcta aaccagtatc accgttttat atggagatat
    31081 caacaatagg aaaatttgaa aaagaattag gtcgaggaat ggcttcggca ccgattactt
    31141 ttgggcattt ataaaaacga gttattcatc tcaatgaatt aaaaagtata gtcaatctca
    31201 taatgcaggc taggttcatt tatttgaaca gagtctgtat ttttttattc taaataaaga
    31261 aacagatgtt tctttatatt gtattttatc ctttaattaa cacaaaaaca gctagtataa
    31321 actaataatg ttaattaaaa gtgtatttta tgaaactatc gttatttatt aatgttgcat
    31381 ttttgtaagt taaaaattgg aaatatagat tgaaaaaatg aaagcaataa gtaaaataaa
    31441 atgaatatat gcgaaaaaat aatttacatt aggaaaaacc ttgtaaaaac agttttttgg
    31501 catatttatt ttttataaat atttgtaaaa taactatcaa ttttttagtt aaaagattgg
    31561 aaatgagtgg gggaggaatt gaagaaagga tttttgagag atgatatagt aggttttatt
    31621 tttagttaaa ataggggaga tagaaaaaat gaaaaagtgt agaaatatta ttttatcaat
    31681 gttatttatt attactaata taacatcact gattcctgtt catgtctatg cggatgcagg
    31741 cagagatatc agcagtaatg tcacttcgtt gaccgtggac ccaacgaata ttacagatgg
    31801 aggaaacata aaagtaaaat tctcgtttga cgaaaaaaaa caaaatatcc aaccaggtga
    31861 ttatctttgg atcaattggc caagtgaagg aaatattcgc ggtgaaggat tccaaaaaga
    31921 aatcccatta atgattgaaa ataaaaatgt tggaacttta acggtcagaa aagattctgc
    31981 gcaggttgtg tttaatgaaa atattaaaaa cctagactca gtagaaggtt gggggcaatt
    32041 tgagatacag gccagaaacg taaccgatac cggtgaagaa aatacgggac cattcaccgt
    32101 gacgagcggt gataaaacag ctactgtaaa tgtgacaaag ccagcttctg gttcttcttc
    32161 tagcgttttt tattataaaa caggagacat gctacctgaa gatactaagc acattcgatg
    32221 gtttttgaat attaacaata acggcactta tgttgaacaa ccagttaaaa tcagtgatga
    32281 aatccaaagt ggacaaagat tagatccaag tacgtttgaa attaatcaaa tacacttagg
    32341 tgaacagaag gtttatagag gagaagaggg aatccaacaa tttttacaag atttccccag
    32401 cgctacattt aatttttcag taactgataa ttacattgaa ataactatac caaaaaactt
    32461 tgtcaatctt aggaaaataa tggtgagtta taagacgatc atagaaaacc cagaacaaat
    32521 aaattttgag aatcattcgg aagcttggtt taaagaattt aataaacctg ctgttgatgg
    32581 agaaagtttc aatcatacag ttaaaaatat ttcagcttct ggtggagtca acggtacagt
    32641 tagaggcgaa ttgaagattt tcaaatatat caatgacaca gagattggta tcccaaatgt
    32701 gactttcgaa ttaagacgag cagatgaaca gcctattcaa ggacagtcta gtatcctgtt
    32761 gacttcgaat gaacagggag aagctagtat caaaggcctg caagtaggag actatgttgt
    32821 aaaagaaaaa gaagcaccca attggattga ttttgatcca ctaagttcaa atgaactcaa
    32881 attctccata aacgaaaatg atacagaggg agtcagttta cctatttata acaagaaaaa
    32941 ggttacgaac atcacagcaa ctaaaatttg gaacggtgga accactccaa gaccgagtat
    33001 ttattttaaa ttattcagag caagtacaaa caattgggaa ccagttcctg atgcagaaac
    33061 aaaacgatta gacaatggaa taacttcagt gacttgggaa gatatccaac agtatgatga
    33121 tagtggaaac gaatatacgt ttaaagtgca agaagtagat caaaacggaa atgattatgt
    33181 cccttcaggt tatcaaaaaa ttgaaaacgg gctagtcgtt acaaatgaga ataaagaagt
    33241 catttcagtc tcaggacaaa aaacatggga agacaatgag aaccaagacg gcaaacgacc
    33301 gacgacgatc acagtaaatc tattagccga cggtcaaccg atccaacaca aagaagtaag
    33361 tgaaaaagat gattggcgct atcgtttcac aaatctgcca aaatacagag acgggcaaga
    33421 aatcatctat actgtaacgg aagacaacgt gcccgaatac agtacgacga ttgacgggta
    33481 taacatcaaa aacagttata caccggaaaa aacaaatata tctataccag gtagccatat
    33541 aacaccgtgg aaaaattttc cagagaagac agagagagag aaaattagaa atctattctc
    33601 tcaaaaattg caaatatttg ctcatacagg agaatccagc gaacaaagaa gcaattatat
    33661 tagtaagaga gctgtaccta aacagataac aaataaatca aaaagcattc ttcctaaaac
    33721 aagtagtaaa aaatctagtt ttgctgtaat cattggttta ttgatagtaa ctatctgtgc
    33781 tgggatattc ttacaaaaat ataaaaaagt ttagttagaa tataatattt tttgttaaat
    33841 atgactgaaa tcaaaagaat aaaattccga tttataatcg aaaaaagaag catttttata
    33901 tatgcttctt ttttcgtaga atcaataaat atggatttgg ctaactatgg aagaatactc
    33961 gtattagttt tcagcgttca tactagttgt tacattgttt gattggccaa aagaatttct
    34021 gatatatttt gtgctaaata aagaaaaaga cgcttgaatt gggaaataag aaaactactc
    34081 tatcattaca aattttcata aactggcaga tgttctaagt aaacaagtat cttttcaaag
    34141 tcggaaaaat ccataatcaa cgtagtggta ttgatatttg gatgaaagcc tacggtatct
    34201 tgacgatcaa tagcagcatc gatcacgact tggatttttt tctctttgtc gtgcatcaat
    34261 gctaatggag tcactgtacc tgctggaacg cctaggaggt caggaagctg ttcttcagaa
    34321 acaaaagata agcgcttttc ttttaattgt tcagctagtt gttttaaatc ggcgtgcttt
    34381 tcatcaggca agatgacaag atagatttgt tttccttttc ttgatttcaa taatagattt
    34441 tttacttgcg gaccaggtag ggaaaaaggg acatttttga ctgacgtaat cgcaggatga
    34501 tcgacttttt gaaaagagat acccagtttt tttagtagtt cataagcttc ttgttcggtt
    34561 gcacgactca tcgcgcatca ccctcctttt tttattagtg tatcataaaa aagagttgac
    34621 aaatgaaaaa taatcatgta aattacacgt aaagttaaaa caaatgacat cgaaaagaag
    34681 agtagccgtt aggtgttttt agagagtctc tggttggtgg aaagaggcag cagttaaccg
    34741 tgaaacacat cttggagtcg attttctgaa gcgtatagta ggaaaatccg gggagcccgt
    34801 tacagctgcg gtcgttgcta gatgaccaga taaggctggc ttttccgtga ggagtcggta
    34861 aaaaaaggtg gaaccacgtg attaacgtcc tttgatcttc ggatcaaagg actttttgtt
    34921 ttcatctgaa cggcaacgac tgtgtgaggt tttttctgca aggaaaaaat aaacagaggt
    34981 ggaaccacgt ataatacgtc ctcttggcat ttgccaagag gattttttta ttttaaagga
    35041 ggaaaagaag atggagtatt tgattgaagt tatgccgcaa ttattagtag gagcactcac
    35101 aacattgaaa ttatttttat ttaccttgat tggctcatta ccattaggga ttgttttagc
    35161 attaggattg tctttgcatt ttaagccgct acgctacttg cttcaaacat atgtatgggt
    35221 tatgcgggga acaccgctgt tgttgcaact gatttttatt ttttatgggt tgccgacgat
    35281 tgggatcgtt tttgatcgtt tcgaagcagc actcattgcc tttatcttaa actatgcagc
    35341 ttattttgca gagatctttc gtggagggat acaatcgatt cctcaaggtc aatatgaagc
    35401 agcgcaagtt ttgcaattaa gtccctttca aacggtgacg aaaatcgtca tcccacaagt
    35461 gacaaagatt gttttacctt ctgtagggaa tgaagttatc aacttggtca aagattcttc
    35521 cttgatctat atattaggtt taggtgacgt aatgcgtgct gggaaaatcg cgatggaacg
    35581 cgacgcgact ttactgcctt tgctaggcgt ggcaatcatc tatcttacat tgactggtat
    35641 tctaacaatc gtaatgaaac aagttgaagg aaaattaaat tattaccgct aactgatagg
    35701 aggaagaaat atgattgaat tgaagaaagt gaacaaagca tttggtgaaa aaaaaataat
    35761 caaagatttg aatctaatca ttccagatgg gaaaacatta gctatcgtag gtccttccgg
    35821 tggcggtaaa accacgcttt tacgtatctt ggctggctta gaaagttctg acagcggaga
    35881 attttattta gacggtgtac cgttcaaccc attcgagctt aaaatgaaag aacaagttgt
    35941 aggagtcgta ttccaagact tccagctatt tccacatctg aatatttttg aaaacattac
    36001 cttagcacca aaaatggtat tgaaacagac aaaagaagaa tacaccaaaa aagcagaaga
    36061 attagcggct tcattaggga ttagtgattt attgaatatc tatccttatc agctttctgg
    36121 cggacaaaaa cagcgggtag cgattgccag agcattggct atgaatccac gggtattggc
    36181 ttatgatgaa ccaacaagtg ctttagatcc tgaattacgc cagcaagtcg agcgtttgat
    36241 cctatcattg aaagaagatg gggtaaccca aattattgtc acccatgatt tagtatttgc
    36301 agaaaatgtc ggtgatcaat tactaaaagt ttccccaatt cattaagaaa ggagaagata
    36361 gagatgaaaa aaaccagttt tctattcgct ttgatcgcag gtcttcttct ttttgcaggc
    36421 tgttcgaaca aaaaaacttc agcagataat tgggcgacta tcaacgaaga gaaaaaaatc
    36481 gttataggtt tagacgatac atttgttcct atgggattta gagataaaga cgggaagctc
    36541 acaggatttg atattgattt agccaaagca gtctttgaac aatatgggat tacggtagac
    36601 tttcagccca ttgactggtc aatgaaggaa tttgaactga acaatggaac gatcgatttg
    36661 atatggaacg gctattccaa aacgccggca agagaaaaga aagtgcaatt tacaaaacct
    36721 tatatggaaa acgatcaagt gctgatcaca cctaaagaat caggaatcac aaactttgga
    36781 caaatgaata ataagagatt aggtgcgcaa aatgggtcat ctggttatga tgtatttacg
    36841 aaacaaccag aagtattaaa agagatagtc aaaaaccaag atgctgtttt gtatgatagt
    36901 tttaatgaag cattgatcga tctgaaaagc agacgggtcg atggtctgct gatggataaa
    36961 gtatacgcag actattattt gaaacaaaga aacgaactag aagacttcaa cataacaaaa
    37021 ggttcttatg agagtgagga ttttgcagtt ggtgcacgca agtcagatag tacattagtg
    37081 aaaaaaatca atgaagccct agatcaacta gagaaaacag gtgaattcca aaaaatatcc
    37141 gataaatggt ttggcgaaga tgttacgccg agaaattaac aaatagggga ctgtgacaaa
    37201 agacgtgtca cagtcccttt ttccgaataa acagtgttct cctgccaact ccttgtgact
    37261 cggagctgaa tggcaggctc acaacctctt ggtaaacggt gttcaaaagc cagtttttcg
    37321 gtattaagcc aaatttatgc aaaaatgtag aaagccattt tcacaaaatt tttcttacta
    37381 ctcgaaacta agcgactttt tcacaacctc ctttacataa ttttattttg ttgtggaagg
    37441 ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa gagatgaatg
    37501 gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc ttctgcagcg
    37561 tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg ggatcgattt
    37621 gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt agaccactat
    37681 catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc ttaccgcttc
    37741 tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca agctgggctc
    37801 gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc tatgttgact
    37861 ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg ggaatcacgt
    37921 cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt ccgcgggaaa
    37981 gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg ttatttgtta
    38041 gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa ccatattgct
    38101 aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc tggaaaaatc
    38161 ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga aaatgttctg
    38221 gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta tatgtgggga
    38281 aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc aacgattgaa
    38341 gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat caattactat
    38401 caaacggcga cgaatgcatt caatccatta aacggagttg gtgctggaaa aatgaatacg
    38461 acaggaaaaa aaggttcatc agaagaaact ggagttcctg gaatgtataa aaaagttgag
    38521 aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg attaaggatc
    38581 ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga aaatggctta
    38641 ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg aatcaattac
    38701 ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga agtcctaggc
    38761 tattgcacct ggtcttatac agatttgctt agctggctga acggttatca aaagcgatat
    38821 ggatttgtat atgttgatta agacgaaaca caagaaggat ctttggaacg atataagaaa
    38881 gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct ttagttcaca
    38941 tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata aaatcattta
    39001 gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag ttctttcaaa
    39061 caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat gagggataat
    39121 aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa acgaaaaagc
    39181 aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg attttatttg
    39241 ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac ggctttcgga
    39301 tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta ggattttgga
    39361 ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt ggcggcatac
    39421 tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa ctccatactg
    39481 gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata aaacaaagtc
    39541 aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat tttacttact
    39601 tcttgattgc acagcctgga agttatttag cagcagtgct attactggca ggaggagcat
    39661 tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca attggagaac
    39721 gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa gcggcaaagg
    39781 aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct gcaaaagaag
    39841 ctgcagaaaa agaagctgca gaatatgaga agaaaaaagc ggtgagccag caaagggaaa
    39901 atactgctga tgaatggcag gaaccagaaa atacagagcc ggagcagcta agttttgttc
    39961 caatcgacag ttttcaagaa aatatccatc ctgcgaatct agagaaacca gtaccagata
    40021 caccaaaaca gaccaataca gcagaaggtt tttcagatga gttgccagag gatgacggta
    40081 cctcattaga atttgagatt gaagcagaac aggaaaatca agactatgaa ttaccgacag
    40141 ttgatttgct tgattctata ccaactgtgg atcaaagtga tgagtataaa aaaattgaaa
    40201 aaaatatcgg cgtattagaa caaactttcc aaagtttcgg tgtcgatgcc aaggtcgtca
    40261 aagccagctt aggaccatcc gtcacaaaat tcgaagtcca gccggctgta ggggtaaaag
    40321 taagtaaaat tgtgaactta acagatgata tcgcgcttgc tttagcggcg aaagatgtcc
    40381 ggatggaagc accgattcca ggtaaatcac tgattggtat tgaagtacca aatggaaaga
    40441 tcagtatggt ttcctttaga gaaatcatcg aagcacaacc aaaccaccca gataaattac
    40501 tagaagtacc tttaggacgt gatgtttctg gacgggtaca aacggctgat ctttcgaaga
    40561 tgcctcactt actcgtggct ggttcgactg gtagtgggaa gtcagtagca attaatggga
    40621 ttatcacaag tatattaatg cgtgctaagc cccatgaagt aaaactgatg atgatcgatc
    40681 cgaaaatggt tgaattgaat atgtacaacg gcatacctca tctgttgacg ccggtcgtga
    40741 cgaaccctag aaaagcagcg caagccttac aaaaagtagt acaagaaatg gaagaacgat
    40801 atgaaaaatt cgcggcaacc ggagtaagaa atatttctgg ttacaatgaa tttgttcaac
    40861 agaaaaactt ggaaaacgga acgaaacatc caaccttacc attcatcgta gtgatcgtag
    40921 atgaattagc tgatttgatg atggtagcca gcaatgaagt tgaagatgcg attattcgtt
    40981 tagcgcaaat ggctcgggca gcggggattc atatgatcct agctactcaa cgtccaagtg
    41041 tggatgttat cacaggaatc atcaaagcaa atgtaccttc cagaatggca tttgcggtat
    41101 caagcggtac agattctcgg acgatcattg attctaatgg ggcagaaaag ctcttagggc
    41161 gaggagatat gctattcttg ccaatgggtg agaataaacc gatccgtgtg caaggagcat
    41221 tcatttctga ccacgaagta gaacgggtcg ttcaatttgt tacagatcag caagaagctc
    41281 attatgaaga gaaaatgatg ccgacagatg aagttgaaac gacaggtgct ccagaacagc
    41341 cacaagatga gctgtttgaa gaagcaaaag cacttgtcgt tgaaatgcaa acggcaagta
    41401 tttcccttct ccaaagaaga tttcggatcg gttacaaccg agcagcacgt ttagtagatg
    41461 aactggaagc tcatggagtt gttggcccgt cagaaggaag caagcctcgg aaagtattca
    41521 ttgagcagga agaaacatca gaaacgttgc cggacgataa tgacatgtaa aacttgtgtg
    41581 atgaagggtt gaaaaacgaa taaccaataa aaagacaagg catgatgata ccaaaagaaa
    41641 aaatggtttt tttccatctt ttctaatacg gtatgatgtc ttgtcttttt agtttttgtg
    41701 agattaaagt tctattcgat ttatttgtga agtattgcat taaggaaatg aatcatgtat
    41761 agtatgtagc gaaactttga gaaaaagagg gaaaatactt tggaaaaaca gtccatttat
    41821 ggcttgacga atgaagaatt aatcaattgg tttatagaaa acggcgagaa aaaattccga
    41881 gctgcccaag tttgggaatg gttgtatcaa aaacgtgtaa gtaatttcac agaaatgacg
    41941 aatctatcga aacaattgat cgaaaaatta tcggagcatt ttatcatcaa tcctctaaaa
    42001 cagatggtcg tccaagaagc ttcggatggt acagtaaaat atttgtttga actccctgat
    42061 aaaaacatga ttgagactgt actgatgaga caagaatatg gcttgtcagt ttgtgtgacg
    42121 acacaagtag gatgtaatat cggctgtacg ttttgtgcaa gcgggctgct caaaaagaac
    42181 cgtgatctga ctgctggaga aattgttgca cagatcatga tggtccaaca ttattttgat
    42241 gagcgcaatc ttggcgaacg cgtttcacat gtcgttgtaa tggggatcgg tgagccattt
    42301 gataattacg acaatgtaat ggactttttg catatcatca atgatgccaa aggattggca
    42361 attggtgctc ggcacattac agtttccact agtggattag cacacaaaat caaggaattc
    42421 gctaataacg gcttgcaagt caatctggct atttccttgc acgcgccgaa taatgaggtg
    42481 cgaacatcga tcatgcggat caaccgaagt ttcccaattg agaaattgat ggaagctgtg
    42541 gatgagtatt tagagaaaac aaaccgtcga atcacgtttg aatatatcat gttgaatcaa
    42601 gtaaatgata gaccagagca tgcgcaacaa ttagcagatc tattaaaaga taagaaaaaa
    42661 ttagcatatg tcaacttgat tccatataat ccagtcagtg aacatgatca atattctcgc
    42721 agtccaaaag ctgatgtatt gagattttat gatgtattga agaaaaacgg cgtaaactgt
    42781 gtgatacgta aagaacatgg tacagatatt gatgcagctt gcggacaatt gcgaagcaag
    42841 caaatgaaaa aaacagttgc caaataatcg tatcctactc gttttttcaa ttaccataaa
    42901 aggagcagtt ttcttaatta aggaactgtt caacttaaat aagagaaaag attctatagc
    42961 gaaagctata aagctttttt tgacaagaaa aaccctcatc aagcaaagaa atgtcctcaa
    43021 tttgatgaca gcctgcttga tgggggtttt agcaattatt taactgattt tcttatatcc
    43081 ttgctggctt tcttgtgtag catgataagt ttctacgtca agaatggcct gtttaaattt
    43141 ttctcgggtg atttcataag gcacatgttt aatatcattt gttgccatgg ctttatctaa
    43201 gattgcttct aaatcggtcg tgacattgag attcatgtcg gttaacgata ctggaagttg
    43261 gttctttttc ataaacacat agattttatc aaacaaatcg aactgctgat ccatcatcaa
    43321 taaggtcagt acaccataac tgacagatgc tccgtgaagg tatccctcca ttttttctag
    43381 aacagtcgta ccgtaataga atgagtgtgc catagcagaa ttatagttat tgttaactaa
    43441 aacagaaacc aatccggtag taacaatgat atccgaaacg acttgttcaa ttgcatatga
    43501 gggacgatcg tcggcactat ctttcaatgc ttgcgtacca taagtcaaga gacgatcaat
    43561 gcacattttt ccgatttgga ttcctaatct atccgtgtag cctagatcat cgccacgagc
    43621 agaaaaagta gattcgactt ctttggataa agcatcgcca atacctgccc ataagtattt
    43681 atcaggtgct tcggcaataa ttgctgtatc aatgaaggtg tgtacaggtg gttttgaagg
    43741 aaagaagagt ccgtccatta cgccttcttc gttatagatg acacataccg cagtgacggg
    43801 cgaacagttc gaaccaatag tgggaaaggt gaagactggt ttagctagtt tttcaccaat
    43861 gacttttaca gtatcgcaag cacggccacc accgactgca aacaggacgt ctgctttttg
    43921 gacactttca tgctggatca actgttcaat atttccataa gttgaattac ccccgtacca
    43981 gagactggcg acaacctcta tttcctgtgt caaagctact tttattttgt tttctgcctt
    44041 tgaaagtgca gtcttccctc caatcagcac tacttttgtc ccatattctt tgacgattcc
    44101 atttgctttt tcatacgcat ctgttccaat ggtataattt ggtaagaaaa cactttgact
    44161 catattcatt tccttctttc ttcgttgaaa cgggttaaaa ttttaaagag tgatcgatct
    44221 gactgcggct gtagatggag tagaggtgaa cctaagacag gataagtgat gaataaggtg
    44281 gcatgaacac cttgaaatca tcaataagta tcctaaaaac gaacaagtac aaaaacattg
    44341 aaaacgacaa taatgaattt ttgttcctct tagtatttct accgattccc tttgcttttt
    44401 tgtaattatc taaaaattct aaaaattaag attattatat gaaaacaggt tttatttgtc
    44461 aattcataat tggttttttt taaagcaaaa gataatctat atcatgatga acaaacagag
    44521 ttttttcctc caattgatgg ctttcctgat ctttcctatt ttgaataaag tgtttctgta
    44581 taatttttta ttttataagt aagataaata atgaaagaat agagatactg attggtagct
    44641 aaagattttt gagcgagaac atttcgtttt ttcaaaagga ctgttagaat aagcaagaac
    44701 aagggggaag acgtatgata atcagtgaat ttgaccgtaa taatccagta ttgaaagatc
    44761 agctttctga tttactgaga ctgacttggc cggaagaata tggagacagc tcggcagaag
    44821 aagtagaaga aatgatgaat ccagaacgaa tcgcggtagc agcggtagac caagatgagt
    44881 tagtaggatt tattggtgca atccctcaat acggtatcac aggttgggaa ttgcatccat
    44941 tagttgtaga aagctcccga cgaaagaacc aaataggtac tcgattagtc aattacttag
    45001 aaaaagaagt agcttccaga ggaggaatca cgatttattt aggtacggat gatttagacc
    45061 atggaacaac gttaagtcaa acggacctgt atgagcatac atttgataaa gtggcttcca
    45121 tccagaacct tcgtgaacat ccgtatgaat tctatgaaaa attaggttat aaaatcgtag
    45181 gtgtcttacc aaatgcaaat ggctgggaca aaccggatat ttggatggca aaaacgatta
    45241 ttcctcgacc aaattctcaa taataaaaag aggttgtgac agaagtaatc agcttcaaga
    45301 aataagaagg aatttacgaa aattacttct tgaatttttg tgaaattcca acttatttcc
    45361 gaagaagcta cttttggaac accgtgtacc agaggttgtg aaaaagtcgc ttagtttcga
    45421 gtagtaagaa aaattttgtg aaaatggctt tctacatttt tgcataaatt tggcttaata
    45481 ccgagaaact ggcttttgaa caccgtttat tcagataagg gactgtgaca agacttttgt
    45541 cacagtttct ttttgtttat tcttttttat ctttgtatgg caataataga caatataacg
    45601 aaaattattt aatggctttt ggaagaccat ggaaaacctt gtacaaagct attttttctg
    45661 aaaaattcct tgaaacctca cgaaaaaatc attattttat gaaaaagaca aaaaaaagtg
    45721 ttgatttttt aataattatt cattaaactc ttaaacaact tcagaaaata ttaattattc
    45781 tgaaaattcc aataaagggg tacgtaaaat gaaaaagaaa tttacatttg gtttggttgc
    45841 ggtatgcggc cttgtacttg ctggatgtta tggcggcagt tcagccacaa gcagtagttc
    45901 agcaaaaagc ggttcagcag atggaggagg cgtatttaac ttagtcgtgc ctcaagaaat
    45961 gcctacagct gacttatcag ttgcaacaga tacaatcagt tttacagcat tgaataacgt
    46021 ttatgaagga atttaccgtc ttgatgaaga cagcaaacca cagccggcag gagctagcga
    46081 gttggcagaa gtcagtgaag acggattaac ttacaaaatc aaattacgag aagacgcaaa
    46141 atggtcaaat ggtgatcctg ttacagcagc ggattacgtt tatggctggc aacgaacagt
    46201 agacccagct acagcttctg aatatgctta cctgtatgcg ccagttgaaa atgcagaaga
    46261 cattacagct ggaaagaaag ataaatcaga actagggatc aaagcagttg gtgactatga
    46321 attagaaatc aaattgacga aacaaacacc atatttccaa tatctgcttg ctttcccatc
    46381 atttttccca caaaaacaat ccgtagtgga agaaaatggg gatgcctatg catctgcaag
    46441 tgataaagct gtttataatg gaccattcac attagaagat tttgatggac caggaacaga
    46501 tacagaatgg acttataaga aaaatgatca ttactgggac aaagatacag taaaactttc
    46561 tgaaatcaaa gtcagtgtag taaaagaatc ttctactgca ttgaacttat tcaaagatgg
    46621 ccaagcagat gacgtgatct tgtctggtga gttagcacag caaaacgcaa acgatccagc
    46681 ttatacttct gttaaagaag cgcggacaag ctatatcgaa ttcaatcaac gtgaaaagaa
    46741 ttcaccattc aacaatgtga acctaagaaa agctatttct tattctatcg atcgtgaagc
    46801 tttagtaaaa caagtactag gtgacggatc agttgtctct acaggattga tcccatcaga
    46861 tatggtaaaa agtccaacaa cgaacgaaga ctttgcaaaa gaagctggaa aattagtttc
    46921 ttatgacaaa gataaagcaa aagaatattg ggaaaaagcg aaaaaagaat tgggcgttga
    46981 ttctttagaa tttgatttga tggcttctga tgatgattca tcgaaaaaag taatcgaata
    47041 tgttcaaaac tcaatccaag aaaacttgga tggcgtaaca gtcaaaccaa cacctgttcc
    47101 attctctgta cgtcttgacc gctcaacttc gggtgatttt gacgcagtac taggcggatg
    47161 ggctgctgac tatgcagacc caagcagctt tactgatttg tttgtcacag gtaattcata
    47221 caaccgtggt cgctggagca atgcagaata tgacgaagca gttaaagcag cttcatcaac
    47281 agacgctggc gatgaacaag cccgttggga tgatttccaa aaagcaatca agatcatctc
    47341 tgatgatatg ggtgtcgttc cggtgtacca aaaagcagaa ggtcacctag tgaatgaaaa
    47401 aatcaaaggt atcgttcacc atgcggcagg cgcttcatgg gattacaaat ggacatacgt
    47461 tgaagaataa tcgttaatac cgtgagcatg agaaaaaacg aggctgcggc aaatgtcgca
    47521 acctcgttct catattcact tatcctaaca aagaaaaaag catgaaaata gcagaaagag
    47581 caattagtat tccggcaatg atcagccaaa agctgtacat accgtagctg gcagacgaga
    47641 gcgtggaaaa ttctggtttt ttctttcggt tccttgttcg tgcaagatgg accgatcgct
    47701 gaaaatgatc gaagaaaccc gaagaaaaga cccataaaaa accgccgata atcagaaacg
    47761 gcaatgacca taagaataga tcattagata attgaatgag tgtaaaggaa tggttgatga
    47821 gattttttat taaaataacc agaatcagta gaaaagctac tgcgtagggg atagattttt
    47881 ttttcatttg attgctcctt tatttttggt tcattatcta ataatgtagc gaaacatctg
    47941 tcagaagtca aaagctaggg ggaaacatta gtgaatagtt atatcaaata tgtattaaaa
    48001 cgtgtctttt tcatgatcat cacgctttgg ttaattgcaa caatcacctt tttcttgatg
    48061 caattgctgc cgggcacgcc atatacgaat caggaacgtt tgagtcctga aacaatcgag
    48121 atgctaaata aacaagtcgg tttggataaa ccagttatcg tacaatatgg gatttatctt
    48181 tctaatttgc ttcaaggaga ttttggaatt tccttccaat ttaaaaacca gccagtcgca
    48241 catttgttag ctggaagaat cggaccatcc ttgcagttag ggttacaggc aattatcttt
    48301 ggaacagtcc tagggacgat tttaggaacg atctctgcca tgaagcaaaa tacatgggca
    48361 gatacatctt ctacactcgt agcgatatta ggtcgttcca ttccaaactt tgtatttgct
    48421 gttttattac aatatatctt tgcaatcaaa ttacaagttt tgccaatcgc aaaatgggat
    48481 ggctttgtgt acacaatctt accaacaatt gcgttggcca tgtcgccgct tgctgactct
    48541 gctcggttta tccgtacgga aatggtggaa gtactgcata gtgattatgt ggaattagca
    48601 aaagcaaaag gattgagccg ttgggaaatc gcctttaaac atggtcttcg aaatagtttg
    48661 attccattga tgactttatt aggaccgtta gctgtagcat tgatgaccgg atcactggtg
    48721 gtagaaaata tctttgctat tcctggtatc ggggaacaat tcgttaagtc aatcacaaca
    48781 aatgattatc ctacgatcat ggctgtaacg atcctttact catttatgct gatttttgtt
    48841 attttgatcg tggatctatt gtacggtcta gttgatccaa gaattcgtgt ttcagaaggg
    48901 agccgaggat aaatggaaat gataccaaag cgttatgaaa cagttgcaga tatccctgcg
    48961 gatgaatttc ttccattaca aaaaaatacc gaagaagaac gtgaacagat tactgcacct
    49021 tctttgaatt ttatccaaga ttcatggcgc cgtttaaaga aaaacaaagc tgccgttatt
    49081 tcaatggttt tactattggt catcattttg atctctgtga tcacaatctt tgtttctcct
    49141 catgatccaa ctgcccaaaa cgtggcttat atcaatttgc ctcctcgtat tccgggaatc
    49201 aatatcgatg gattgaatgg aaaagcaatg gttggtggtg aacttgttga taaatatgct
    49261 caagcaaacg tcccttcaaa cgtaaatttc tttttaggaa cagacggttt gggacgtgat
    49321 gtattaagcc gcttatttat gggaatgaga atctcgttgc tgatcgcatt tattgctgca
    49381 ttactagatg taacgattgg tgtagcttac gggttggttt ctggtttgtt aggcggacgt
    49441 gtcgataacg tgatgcaacg ttttttggaa atcttatcag gaattccaaa cctcgttgtc
    49501 atgattttga tgttggtcgt ttttgaacca ggaatttttt caatcgtggc tgctatggcc
    49561 atcacaaact ggataccaat ggcacgtatc gttcgtgcac aaacaatgaa attaaaagat
    49621 caagaatatg ttttagctgg attgacatta ggtgaatcaa gaatgaaaat tgcattcaaa
    49681 catattttgc cgaatatctc tagtgtcatt attattcaaa tgatgtttag tattccatct
    49741 gctattttct tcgaagcctt tttaagcttt atcggtttag gtcttacgcc tccgtcagct
    49801 tcattaggaa cgatgttgag cgaagggtac aagacattcc tgtatctgcc ttatctatta
    49861 tggattccgg cagtaacttt atcggttatc atgattggct ttaacttact tgctgatgga
    49921 ttgcgtgatg cctttgatcc taaaatgaaa gagtgaagac gatgacgaaa attttagaag
    49981 tgaaagactt agaaatctct tttgatacgt atgctggaaa ggtacgagcg attcgcggtg
    50041 tcaattttca tttgaataaa ggagaaacat tggcgatcgt tggggaatct ggaagtggaa
    50101 aatcagtgac gaccagaagc atcatgcgct tgctgtcaag caacgccaat atagatgctg
    50161 gtcaaatcct ctttaaaggt aacgatatcg ttggaaaatc agaaagagag atgcaaaaaa
    50221 tccgtggtaa agaaatagcg atgattttcc aagatccaat gacctcttta gatccgacga
    50281 tgcccattgg gaagcaagtc gctgagtccc ttagaaagca taataaagtt tcaaaaaaag
    50341 agggacaaaa agctgcatta gaattgctta aattagttgg aatacccgaa gctgagaaac
    50401 gtatcaacag ttatccgcat cagttctcag gaggtcagcg tcaacggatc gtgatcgcga
    50461 ttgcactggt atgttatccg gaaatcctga ttgctgatga acctacaaca gcgcttgatg
    50521 tgactattca agcacagatt ttggagctgc tgaaagaaat tcagacaaaa atcgatacat
    50581 caattatctt tatcactcat gaccttggtg tagtagcgaa tgtcgctgat cgtgtcgctg
    50641 tcatgtatgg aggaagaatc gttgaagttg gaacatcgga agaaattttc tacaacccgc
    50701 aacatcccta tacttgggga ctgcttggtt caatgccgac attagatagt gcgaacgatc
    50761 gattgtatgc tattcctggt tctccaccgg atttattgaa cccgccaaaa ggagacgcat
    50821 tctatccaag aaatgaattc gcgatgaaaa tcgatgcaga acaagaacca ccattttttg
    50881 aactatcaaa aacacacaag gcagcaactt ggctacttgc tccgcaggca cccaaagtga
    50941 caccgccaga agaaatccaa cgtcgctggg ctatctttaa agagaaacaa aaacatactt
    51001 acggtcaagg aggaattgct gatgccaaat aaactacttg aagttaaagg attgaaacag
    51061 tatttcaatg taggaaaaaa gaatgaagta catgctgtaa atgacatcag ctttcacatt
    51121 tatgaaggag aaacattcgg tttagttgga gaatctggaa gcggaaaatc cactactggc
    51181 cgtacgatca ttcgcttgaa tgaacctact gatggtgaga tattattcga cggtcaagat
    51241 ataacgaaga tcaaagataa aaaaggtttg acgaaattcc ggcatgatgt tcagatgatc
    51301 tttcaagatc catacgcttc gttgaatcct cgtatgaaag tcagagatat cattgccgaa
    51361 ggaattgatg ttaatggact agctaaatca tctgaagagc gtgcaaaaaa agtcgatgat
    51421 ctattgagaa ctgttggatt gaatccaagc cacggtactc gttatcctca tgaattttca
    51481 ggtgggcaac gccagcgtat tggtattgca cgagcattgg cagtaaaacc gcgttttatc
    51541 atttgtgatg aaccaatttc tgcactagat gtgtcgatcc aagcccaagt ggtcaatttg
    51601 ttgcaagatc tccaaaaaga acatcaattg acctatctat ttattgcaca tgatttgtcg
    51661 atggttaaac atattagtga ccgaatcggt gtaatgcata acggcttgtt attagagatg
    51721 ggaacaagtg atgaaatcta taatcacggt gttcatcctt atacagaaag tttgttatct
    51781 gctattcctc taccagatcc agaccatgag agaaaacgca gaagaatcaa atatcaacct
    51841 gaaccagatg acggacaagt acgtcaactt cgtgaaatcg caccagaaca ttttgtctat
    51901 gcaactgagc aggaagtccc atattacgca aaaaaactaa aacgacaaaa ggaatctctt
    51961 ctggttgcta actaggaggg acatagatgc taaaagcttt taaattccgt atgtatccga
    52021 cagaagaaca aaaacagcaa ttgattcgta cttttggatg tgctcgattt acctataacc
    52081 atttgctgaa aaagcggcag aaaagttggc aacaaacagg agtagccaat ttttcgctca
    52141 cacccgctac attaaaaaaa gaatacccat tcttaaaaga agtagacagt cttgctttag
    52201 caaatgcaca gcttaatttg gatcgggctt ttcgcaatta tttcaaggga cgtgccagct
    52261 tcccaaagct taaaacgaaa aaaagtatgt ggcaatctta tacgaccaac aaccaaaccc
    52321 gtacgatcta tctggaaaat ggctacttaa agttaccaaa acaaaaagaa ctaatcaaga
    52381 taaatcagca tcggccagtt gaaggatcga ttcgctccgc tacgatttct gctcgatata
    52441 atgaagaatt ttatgtcgca ctactttgtg atgtttcgcc agtaaaaaaa gaatctttag
    52501 ctaaatggat cgggatcgcc tatcatccga agacattgat ccaaacatct cgacctctag
    52561 aagtaacttt accaaaattt caccagacag aagaaaagct gcaacatgca cagcggaaat
    52621 tgaatgtgaa agtccgctcc gctcaccata gaaagatcag gttagatcag gcaagcaatt
    52681 atcagaaaca aaagagaaaa gtaatggatc tttatctgaa acaaaagaac cagcgagaag
    52741 attatcttga acaattatct gggaaattgg tcaaacaata tgactactta tttgtagaat
    52801 cttttccaaa agaagaggca catgctgatt tttctattca cgactggcat aaattaataa
    52861 caaaattgcg ttataagtcc caatggtata ataaaaaatt tcttttgatc aataccgacg
    52921 gagcagaaga aagcaattcc gtaagaaaga gccaagtagt agaaaaaatg ggcagacatt
    52981 cggttatcaa gggataaaaa atgaatgaaa ctgataggag cgttagggtt agccttgtta
    53041 ataaaaagtc ttaatgactt ttgtttctag gaatttttct tttgaagaaa agctcactaa
    53101 ttatgacaaa ccaataaaac aatagcagaa aaagttcgta cgagcttttt ctgctattgt
    53161 taatttttta ttcagaaagt ttacgaatac atcaaaattc tgaaacaaaa aacgtaactc
    53221 acaaagagtt gtttttgcgt tttttcttga atgattaggt ctgaatcttt tgctcacaac
    53281 cttattcatg gtgccccggc ttgagctgat agatttttga aggacggccg attcctacag
    53341 gacgttcacc gatctcatcg aaatattgga gcatagcttt cttaaaattg gaatgatcga
    53401 tcgttttata atcgatccct aagaatttag caaatacttt tcgagcttcc gtaatcgtga
    53461 aatctttacc taaaacttgt agaacttgcg gctcgtgttc cattttattg actacacggt
    53521 tgaatgcttt caagatgatt tgactatggt caaaagccaa agtatctttg ccagaagact
    53581 ctccagtgac taaatcaagc gagatagcca cttctccgct agataaatgg atcttgttac
    53641 tatgacgttc tagtgtgaac cagcgtactt ccttggcatc atctccggcg attagcggtt
    53701 cttctccaat aaaggctaag tagctgactg tgacgaccca gcctcgcgga tctcgattag
    53761 gcgtactgaa tgtatgcagt tgctcaatat tttcttttga aataaccaca ccagtttctt
    53821 cctttgtttc tcttaagacg ctttctccag ttgactcatc cttttggaca aagccaccag
    53881 gcaatgccca tgaatttcga taaggatgcc cttttctttg gatcaacaaa actttcagct
    53941 gatcttcttc tttgttatag cacatcagta cgatatcgac agtcaaagag ggcttgtcat
    54001 attctggacg ttcctgtttt tgataccagt taagaaattc ttcttcactt gctttatgtt
    54061 cataatataa tttttcttct tctttagaag caaaacggtt catctgacca cctccattga
    54121 cagtaaaagt actttttacc ttattgtagc agactctgaa aaaaaaccaa ggatttactt
    54181 gaaaaatcta ggttatcatt taaatatgaa aaataaatgg aagtatgaga ttgaataaaa
    54241 agaaaagcag ataaaacggc aatactttat accgctcttc acgaatggca aagaagccac
    54301 aaataacgat atatacgtca atgataaaac gcaaaatcca agctgctgtc ataaaactgt
    54361 tcaaatgccc atggaggtta aaataaccat acatacgaat ataaaaatag ctgaatatta
    54421 aatgtgctaa tgaaagaaaa gcaatactaa gtgtaaaaaa aagatgtttc ttctgcatga
    54481 ttgttccagt cccttactaa gatagatagt ctttattata ccacgtgtga ggggagaaat
    54541 aaaaagccgt tttttagtag atatgaaaca aaacaaaaac ccgcatttat tcaacctatt
    54601 catcctttta aaggatagat tgaacgtaga tagaagtcgt ttatccagtc tttttcattt
    54661 tgaaaaaaag ctaacagcat gcttttttta tggtatacta gcaaggaaac gaattcgcat
    54721 catgcgataa aggaggaaga gccccgtggc agaaaaggaa actttttata tcactacgcc
    54781 aatctattat ccaagcggca aacttcatat cggcaactcg tatactacga ttgcatgtga
    54841 cgcaattgct cgttataaac ggttgatggg ctttgatgtg ttttatctca ctggagtgga
    54901 tgaacatggt caaaaaatcg aaacaaaagc agaagaacta ggtgtaaaac cgcaagaata
    54961 tgtagataaa atggcggctg atgtcaagaa attatggaaa acgcttgata tcagttatga
    55021 taaattcatt cgcacgacag atgattacca taaagcagct gttcaaaaaa tatttgatcg
    55081 tttattagaa cagggagata tttacttagg tgaatatgaa ggctggtact ctgtttctga
    55141 cgaagaattc tttacagaaa cacaacttgc agaagtgtac aaagatgacg aaggtaacgt
    55201 gatcggtggt aaagcgccaa gtggacacga agtagaattg gtaaaagaag aatcatactt
    55261 cttccgcatg agcaaatacg cagaccgtct attggaatac tatgaagaac atcccgaatt
    55321 catccagcca gaatctcgta aaaacgaaat gatcaacaac tttatcaaac caggattaga
    55381 ggatcttgca gtttcacgaa caacttttac ttggggagta ccagtcaaga gtgatccgaa
    55441 acatgtggtg tatgtatgga tcgatgcatt atccaattat attactgcac taggatatgg
    55501 ctccgaagat gaaagtctat tcgaaaaata ctggcctgca gatgttcaga tggtcggtaa
    55561 agaaatcgtt cgctttcata cgatctattg gccaatcatg ctgatggccc ttgatttgcc
    55621 tctacctaaa aaagtatttg ggcatggctg gctattgatg aaagacggaa aaatgtctaa
    55681 atcaaaagga aatgtcgttt atcctgaaat gcttgtggaa cgttatggtt tagatgcact
    55741 ccgttattat ttgcttcgtg ctgttccgtt tgggtcagat ggtgtcttta cgccagaaga
    55801 ttttgtttcc cgtgtcaatt atgatctggc aaatgatcta gggaacttat tgaatcgaac
    55861 gattgctatg atcaacaaat attgtgatgg actcgttcct gactatgcct cacttgtcac
    55921 tccatttgat agtgaactgt ctacgacggc tgctaacgtt gtcggacgtt accatgatgc
    55981 aatggaaaaa atggaattca atacagcatt ggctgaaatc tgggtgctga tttctcgtgc
    56041 aaacaaatac attgatgaaa cagaaccatg ggtattagca aaagacgaag aaaagaaagc
    56101 tgaattgaat agtgtcatga tccatttagc tgaatctttg cgtatcgcag cgatattact
    56161 tcagccaatc atgacagaaa cgccagagaa gatcttcaat caactaggat tggactctga
    56221 aacaatgaat cttgaaggat tacactttgg cgaatttcct tcaggaacaa aagtagttgc
    56281 aaaaggtaca ccaatcttcc cacgtttaga tatggaagaa gaagttgctt ttattcaaga
    56341 aaaaatgtct gaaggtactc aaacaaacga agatacagtc aaatgggatc cagaagaaac
    56401 agaacttgtt tcaacgaaag aaaaacaaat caaatttgat gtatttgaaa aagtagaact
    56461 aaaagtagca gaagtcatca actgtcaaaa agtagaaggg gcagataagt tgctgcaatt
    56521 ccgactagat gctggagaca gccaagaccg tcaaatcttg tcaggaatcg ctgaatttta
    56581 tcctgatcca agcgaattga tcgggaaaaa agtcgtcatt gtagcaaatc tgaaaccacg
    56641 aaagatgcgt ggacaaatca gtcaaggaat gatcctttct gcagaagcac cagatggctc
    56701 tttacaagta atcgaagcac caaaatccat gccaaatggc tcagaaatcg catagaaatt
    56761 caaagggggt atgacactag ttgtgtcata cccccttttt ccgaaatttg agaagcaatt
    56821 ttcgtaaatt ccttcttatt acttgaagcc aatcatataa tacagaaaca gagaactatc
    56881 caaaataaat cctagaaaaa gaagtacgag cttcgctgat ttttgttaat ttagaataat
    56941 actaatagga atcgtaaaaa cagaaaaaaa gcataatgat aaagggtcgg gcagatttta
    57001 attgattcat ctggtactct tttttattgt ccttacattc ataaagtttg aatgcaatga
    57061 ctttattaca tctatattta tatctaacag tagcgttgat gtgttaatta taagttctat
    57121 cactttatgt tcaattagtt tgtgctctta tatgtgtgat tgaaaatata gataaaaaaa
    57181 caatcatcgg ctttgacttc gatgattgtt ttctttattt tgtaaaaatc ctatcacttg
    57241 attttatggt aaccttttat ttttgtcttc aaacggcttg gtaagagagc agtaagcagt
    57301 gcaaatggga tcgaaaagac ataccagaaa atcgtacgtc cgataccata atgttgatag
    57361 agctttgtca acatcacgtg taacaagatc aaccctaaaa gcaaggagcc agctataaac
    57421 caatgattat cccaatgcat gacttcacta agtgccatca ctccaaaagg atagaaataa
    57481 aaatagatcc cgactaaggt catccgccag ttctttgtaa atgttccgat attcaataaa
    57541 aagaaaatcg ctgaaagcaa aataccgata ggcggaaaaa gcccaaccaa aaaggaatac
    57601 aacatccccc acaagatcat cacaggacct ttgatcaatg caacgattgc gatgaacaaa
    57661 gtcagcaata ttagtttttg tgataacgtt gcaacagtca ttaatccaaa taaaattaat
    57721 gtgaaccaat gccaatggga ctgctgttgt tctttacggg aaaaatcgac ccggttggat
    57781 aaataatctg ctaatttcgg ataagaacgc ttaaaatcca taaactgttc ctccttcgtg
    57841 gaaaaggtag gtttagtata cgaaaaataa aaaagaaata catccgtctt aagagggagt
    57901 ttttcactga aagtggagaa aaaagaatgg taaattaaaa tattctcagt tatactgaaa
    57961 attataccaa atttcaaaga agaaagagga tgggaatgaa aggcaaacta aaacgagaaa
    58021 tcaatctgtt tggcgcatta gctaccgtta tgggaaccgt gatcggtgca ggcgtcttct
    58081 tcaaaactgc tgctgttact gctagtactc agtctacaag tttgacattg ctagcttggc
    58141 ttttgggtgg tttcttaacg atctgtgctg gattgacagt ggctgaatta gctacagcaa
    58201 tcccggaaac tggtggagct gtaaaatata ttgaagctgc gtatggaaaa ttgcccagct
    58261 ttttattagg atgggcgcaa agcttgattt actttcctgc taatattgct gcattatcga
    58321 ttatctttgc gacacaattg acgaacttat tacaattatc taccgattat cttttgttga
    58381 ttgcagtgat caccgctgtt tctgtgacag ggttgaattt gttagggaca aaagtcggtg
    58441 cttctgtaca atcagtgacg ttgattgtta aattaatacc aattgctgtg attgtcatat
    58501 ggggattatt gaccccagga caaggaactg tccagttatt tccaatcgaa gctggaaaag
    58561 atgttacttt tgtcgaagga ttgagcagtg cgttgttagc aacgttgttt gcttatgacg
    58621 gctggttagg tgtcggtgca atggcagggg aaatgaaacg gccggaaaaa gatttgccta
    58681 aagcaattat tcttggtttg agttttgtaa cagtcgttta tctattgatc aattttgttt
    58741 ttttgaaaac tttgccgatt gatcatcttg ccggtaattt gaatgcagct tctgaagcat
    58801 cagacgtcat ttttggagga atcggtggaa agctggtcac tattgggatc ttgatctcgg
    58861 tatacggtgc attgaacggt tatacactaa ctgggatccg cgtgccttat gcgatggctt
    58921 tagaagacga gctacctttc agtaaacagc tgacaaagct ttcaaagaag tttacggttc
    58981 cttatgttcc tgcggttttc cagttagcag tagcttgtat tatgatgagc cttggttctt
    59041 tcgacttttt aacagacatg ttgatttttg tgatgtggct attcagttta ctgattttta
    59101 tcggtgtctt tattttaaga aaaaaagcgc cggaattgcc acgtccatat aaagtaccac
    59161 tttatccaat cgttccgatt attgcgattc tcggtgctat tttcatttta ggtatgacga
    59221 tgatgacgca aacgaaatta gcattgatcg gtataggtgt taccttgata ggtatcccag
    59281 tctattatca aaaaaagaaa aaacgctcag aagagtaaaa tatttcaaca acagacagaa
    59341 aaagtacgaa ctaggtcctc tagatcttcg tgctttttct atttcaataa aacaagttct
    59401 tctattttga tttttgctac ttctgcaagt agtgcttatg tgctaaagta agaatgaaaa
    59461 ggagagataa acatgatatt tgattctcat acccatttaa atgctgaaca gttcaatgaa
    59521 gatattccag aaacgattca gcgagcacaa gaaatggggg taacgaaaat ggcggtcgtg
    59581 ggcttcgata cgccaacgat tgaaaagtct ttgcaattaa gccatgacta tccaaatata
    59641 tacagtatta tcggctggca tccgacagag gctggcagtt atacgaaaga aatcgaaaat
    59701 aaattacaag aacaattgac tttaccaaag gttgtagcat taggggaaat tggcttggat
    59761 tatcattgga tggaagaccc gaaagaagtc caagataaag tatttcgcag acagattgct
    59821 atcgcaaaag aaatgaacct accaatcagt attcatacta gagaagcact tgaagacacg
    59881 tatcaaatcc taaaagaaga agatgttcga gatatcggtg gaatcatgca tagtttcagt
    59941 ggtgattatg aatgggcaaa acgatttctt gacttaggga tgcatatttc atttagcggt
    60001 gtcgtcactt tcaaaaaagc attagacgtc caagaggctg cagcaaatgt accaatcgaa
    60061 cgattacttg tggaaacaga tgccccttat ctggcaccag ttccttttag aggaaagcga
    60121 aatgaaccag gctatactcg ttatacagta gaaaagattg ctgaacttcg gaatcttccg
    60181 acagaagaag tggctgccca aacatggaca aatgcgcacc gattatttgg tctaagcgaa
    60241 catggataag atgaagatcc aagagattat agtcgttgaa ggaaaagacg atacaagaag
    60301 gctgcgggaa gtagttgatg cagatacgat agaaacaata gggtctgcaa tcaatgaaga
    60361 gatcctgatg caaattgaac atgcccaaga gactcgtgga gtgatcgttt ttaccgatcc
    60421 tgatttttca ggagaaaaaa taagaaaaat cattatggaa gctgttcctc aggcaaaaca
    60481 tgcttttttg ccgcgcacac aagctaaacc aaagaaaaag ggaagccttg gtgtcgagca
    60541 tgcaagtgat gctgctattt tagaagcatt gaaaaaggtc gtgacgccag acatttccca
    60601 aacggctgtt tctgaaatca ctagacaaga ccttttagac tatggtttaa tagctggggc
    60661 acaagcaaaa gaaaaacgag aaaaactagg tgacgagttg cgcatcggtt acacgaacgg
    60721 caaacaattg gaaaaacgtt tgaagatgtt tcgtattacg ccgaaagaac tcgcccaagc
    60781 aatgaaaata gtggaggaac aacatgagtg aatatcgtga aattgcgaca ccctctagaa
    60841 caaaagagat tttattgaaa catggttttt catttaaaaa aagtttagga caaaattttc
    60901 tgactgaacc aaatatttta aggaaaatcg tagaaactgc gcaaatagat gaacatacga
    60961 acgtgatcga agttggacca ggaatcggtg cattgacgga acaattagcc aagcatgcaa
    61021 aacaagtcgt agcatttgag atcgatgatc gtttgatccc tgtattggct gatacgatgc
    61081 aaccctatga caatgtgact attgtacatc aagatatttt aaagaccgat ttgtcaacag
    61141 ctgttagaga aacatttcat gaggagcttc cgttaaaagt cgtagcgaat ttaccttact
    61201 atattacgac accgatcatg atgcattttc ttgaatcaga tttggttgtg gatgaactag
    61261 tcgtcatgat gcaaaaagaa gtagctgatc gtatctctgc tgaaccagga acgaaagctt
    61321 atggttcatt atcgattgct gttcaatatt atatggaagc cagtttagca ttcatcgtac
    61381 caaaaacagt atttgtccct cagccaaatg tagattcagc gattttgaaa ctgacaagaa
    61441 gagatatacc ggcagtcgaa gtgacagacg aaaaagcatt tttccgattg acaaaagcgg
    61501 catttcagca aagaagaaaa acgctttgga ataacttgca gcattcgtat ggcaaagatg
    61561 accagacaaa agcatggtta gcaaaaagct tggaaacagc tggaatcgat ccaaaacgtc
    61621 gtggggagac tttgtcatta caagaattcg ccgcattaag caatgcgatg tcagaaaata
    61681 tgcagtaaaa aaagaggttg tgacagaagt tgtgaaaaag ctgtcctgca tcaagtaata
    61741 agaacagcca aacaaaaata gttcctcatg tttttcgttt gtttgggctt attaccgcag
    61801 atgcaagctt ttgaacaccg tttaagaaag aggttgtggg cctgccgttt aactctaagt
    61861 cacaaggaac aatttcaaaa aacagcttct catgtttttg agttagttgg tcttattact
    61921 tgatgcaagc ttttgaccac tattatgccg aacaaggaga tgtgacacaa attttgtcac
    61981 atctcctatt tttgtttctt gatcaaaaaa ttcttatact tgatactcac actcattttg
    62041 tatggattta gaaaagaata tgtgtcttga cagttattag taagtgagtt atactaagtc
    62101 gacatttatg tgtcaagaca tattaggaga gagaaaaaat gagaaaaaat tcagttcgaa
    62161 aactaacgat ttctgcttta ttgattggga tgggggtcat tatcccaatg gtcatgccta
    62221 aaatcatgat tccaccagct tcctttactt tggcgtctca tgtgccatta tttattgcga
    62281 tgttttttac accaggagtt gcagtggctg ttgcgctagg tacgacattt ggtttctttt
    62341 taacaacgcc ggttatcatc gcattgcgag cattgtcaca tcttgtgttt gcgttgattg
    62401 gggcttggta cttgcaaaag catccgagta tcgttttaaa aaatggacag tttacttttg
    62461 ctaattggcg tttccaaggg ttcaattttg tgatcggtgt gattcattct ttagcagaaa
    62521 tgctagtagt cagcatcttt tactttattg gtaatatgcc tgaaacatat tattctcaag
    62581 gatattttta tacagtattc atcttgatgg ggattggtgg gcttatccac agtttagttg
    62641 attataatat tgcttatttt atagcaggaa cactcagcaa atattttgat atccccgtat
    62701 ttacggcagc aaaaaaagaa aatcggaaag agtcgattca agggtacgcg aagaaaacga
    62761 catattagac atgatctctc aaaaaaaaaa ctctcatcta gtaatggata ataaatcctc
    62821 taagatgaga gttttttgtc ctaaaaagag ctgcaccaac atcttctggc acagctctaa
    62881 cagggggcaa tttatggaag tttgatgact tgttctgttt ctttatcaaa gaagtggcct
    62941 ttgctgatgt tgaaggcaag gtcgactatt tcgcctggtt tatggaaatc tcttgcatct
    63001 acttttgaga tgaactcagt agaaccagtt tttgtgtaaa gcatcgtttc agctccaagt
    63061 aattcggaaa cgacaacttc tgatttcact acggcttcag gtgaagcttc aagggctact
    63121 tgttcactgt ggatgtcttc tggacgaata ccgaagataa cttcttttcc ttcataacct
    63181 ttttcaacta atactttgtt ttttccttca ggaatacgaa gcttaagccc atgtccatct
    63241 gtgataacac catttttcaa tgtcacatta aagaagttca tggcaggaga tccaataaag
    63301 ccggcaacga acatattgac gggtgtatca taaacttctt tcggtgtacc gatttgttgg
    63361 ataaatccgt ctttcatgat aacgattcgg tcagccatag tcattgcttc tgtctgatcg
    63421 tgagtaacat agatggtcgt tgtttcaaga cgctggtgaa gtttggcaat ctcagcacgc
    63481 atggctacac gtaatttagc atctaaattt gataatggct catccattaa gaagactttt
    63541 gcatcccgaa cgattgcccg tcccaatgcc acacgttggc gttgtccacc agataaagca
    63601 gctggttttc gtttcaagta ttctgtcaga cctaagatct ctgctgcatt gtccacacgt
    63661 tttttgatgt ctgctttatc atatttacgt aatttcaagc caaaagccat attatcaaaa
    63721 acagtcatat gaggatacaa tgcgtagttt tggaaaacca tggcaatatc acggtcttta
    63781 ggtgccacgt cattcatgac ttttccgccg atatttagtt ctccttcaga gatatcttcc
    63841 agtcccgcga tcattcgcaa agtagttgac tttccacaac cggaaggacc aacaaaaacg
    63901 ataaattcac ggtctttgat tgatagatta aaatcagtta cagaataatt ttctgcattg
    63961 tcatattttt tatatacgtt tttcagagcc atttctacca taatacgttc cacactttct
    64021 tttttagttt tattaactat ttaaagtata aatgaaagcg ttaactaact tcaatgtcat
    64081 gttgaacaag aattttttct tttttttgtc aatgtgctag ttttaagctt taataaatat
    64141 ccataagaaa taaaaactga tacactggag taaataagta tgttaacaat atcaaaagga
    64201 gtgtctctta tgaaaatcgc tttgatcgct catgaccgaa aaaaacctat gatggtgaaa
    64261 ttagcaacag cgtataaaac aatattggaa aaacatgaac tttttgctac cgggacgact
    64321 gggcagagga tcacggaagc aaccggcttg ccgatccatc ggtttaaatc cggaccgtta
    64381 ggcggggatc agcaaattgg agccatgatt tcggaggatc agttagattt ggtgattttt
    64441 cttcgagacc cgctggctgc acagccccat gaaccagatg taacagcact tatccgttta
    64501 tctgatgtct atgagattcc gttagctacg aatatcggaa cagctgaggt gctactaaga
    64561 ggactggaag ccggcttcct agattttcga agaatcgtcc atgaaataga caagcatcca
    64621 ctttcatttt gatggataag cgtatggaaa aataacgttt aatgttcgcc tatatgtagc
    64681 tataaaagct aaacaaactg ataatatgcg atataatacg aacgtattgg ataatataaa
    64741 caataatatt agtttttcgt atttgcagta aatgtgaaaa tatgctatag tttctgtggg
    64801 aaaagatccc aaaaataata cagagtagaa aataaagcgt taagtgctaa gaggatggga
    64861 tgttgcctct tggacgaagg acgtaatgtt cgcggtttta ttttcgcatt cgctgcatga
    64921 tacgatgtag cagctcttaa aggagatgct aaaaatgaag aaacaccggt tagacgcacg
    64981 tatgattgct attatgggct tattgattgc attgatggtc actttgtccc gactggtagc
    65041 aatcgagacc ccatttatta aaatcagtgt cacatttatt ccacaagtga tcatgggcat
    65101 tctttttggt cctttttggt cagggatagg cgcagtttta gctgatttag taggaatggc
    65161 cctcttctcg aaatctgcat tctttattgg atttacattg aatgcattta ttgaaggagc
    65221 aatctacgga ttctttttct atcgaaaaga gatcacttgg aaaaatgcca ttctggctac
    65281 gcttagtgtc acgctgatca tcaacttatt tttgacacca ttatggcttg cgttgatgta
    65341 ccatgtgcca ttgttcagct gggtcgtttg ggcgccccgc ctgttaaaaa cagtaatatg
    65401 gttaccgatt caatcaattg ccatttatta cgtaggacgt agtattcctt acaaaaaaat
    65461 tttaagaagt ttagcgatcc acgctaaata aaaaacaagc agtcttccca tcccagaaga
    65521 ctgcttgttt ttattgtgct gtgaattgtg cttgatagag ccgtcggtaa taaccatctt
    65581 tttgaagcag ctcatcatgg gtgcccattt cgacaatagc tccctgatcc atcactaata
    65641 tctggtccgc atttttgatt gtggacaggc gatgggcaat cacaaaactg gtttttcctt
    65701 ccatcattgc taagaaggct tgttggattt ttttctctgt caatgtatcg actgagctgg
    65761 tagcttcatc taagatcaac atagggggat tactgatcat cgttcgagca atcgtcaaca
    65821 gttggcgttg tccatctgat atctttaacc cttgaccgcc aatcttagta tctaattttt
    65881 ccggcaaacg ttctacaaat tcatacatat aagaggcttt tagggcatca ttgatttctg
    65941 cgtcacttgc ttccggattc ccaaaacgaa gattttctcg caatgtactg tcaaatagcc
    66001 aagtatcttg taacaccatt ccaaaacttt tacgtaatgt atcacgttgg atagagcgga
    66061 tgtcatggtc atcgactgta attgttcctt ttgttgtgtc ataaaaacgc atcagcaaat
    66121 taacaagtgt ggattttccg gcccctgttt ttcctactat agcaatggtt tgacctggat
    66181 aagcagtaaa attgaaatct tcgatcaaac gctgcttggg gtcataagaa aaagaaacat
    66241 gatcaaaaga gacttttcct ttgatatttt tgggttccaa ggcataggca tctggcaaat
    66301 caggcttttc ttctggctga tcgatcaaat caaatgctcg ttctagacca gaaaaagcgg
    66361 tttgcagttg tgtcgtgatt ccagaaagtt cgataaatgg tttagaaaac tgacttgagt
    66421 agatcgtaaa gctggaaatc acaccaacag tgattgacga accactcttc aatgccaata
    66481 ggccgccaac taaaccaatc gataaataag caaggtgatc tacaaaacga gaagacgggt
    66541 ttgtcaagga agaagaaaat tgtgcccgtt gtcctttttc atatagatca gcatttagca
    66601 gttcaaattg ctgttgacta gcttcttctt gctgaaaagc tttcacgatt ttctggttac
    66661 cgattcgttc ggtcacaaag cccgagatat ccccaataat cctttgctgt ctatcgaaat
    66721 ttgtttgtga agcacgagca acgatccaac tcacaaggaa aataattggt gtagaacaaa
    66781 gaacgaccaa tgtcagaagt ggacttagac gcatcataaa aataaacgaa agaatgatga
    66841 ttgccactcc agaaaataat tgattgaagg ccgcagaaat tgcaatggaa atattgtcca
    66901 tatcatttgt aaatcgactg acgatatttc cgtgggagtt ttgatcataa taacgaagtg
    66961 gcaatcgatt cagatgagca aatgcatctt ttcttaattt tgcaacggat aagtaagcta
    67021 accgattgct taacacttgg atgagccatt gactgactac gttgattaaa acgataccac
    67081 cgaatagaat aagtaaatgg aacagtcgat tgaagcggac ctgtccttct ccaatcattt
    67141 gatcgatact ttgaccaatt tgtaacgtca tcacaactgt tgcaatccca ttgatgattc
    67201 ctagtatcac agctagccaa atgtcttttg cataggcagt aaggtaagga atgaatcggc
    67261 ggagcgtctg caaggataat ttttttactt tcataactat tcttcctcct gtgatgcgac
    67321 gatttcctga tattctgctg attgagcaag taattcttca tgggtaccct gagcagcaat
    67381 cttaccttga tccatcacta agatatgatg tgcttcttga atagagcgga cacgttggga
    67441 gataataatc actgtactgc caagataagt ctgtagcgcc ttacgcaaat ccaagtctgt
    67501 ttgataatcc aacgcactta aagagtcatc taaaatcagt aatgctggct tggcaatcaa
    67561 agctcttgca atcgtcagtc gctgtttttg tccgccagag aaatttttcc cattttccat
    67621 gacttttgta tctaaaccat ttggaagctg acggacaaat tcttctgcct gagcgatttt
    67681 cagagcttcc caacattctt tttctgtggc gtctttctta ccccattgaa ggttttcacg
    67741 aatagtcccg gtaaatagta cagaagtttg gggaacaaga gcaatttgct gacggagatg
    67801 atccagctgc caagaacgaa catccattcc gtccattata actgtaccgg aactgacatc
    67861 atagaaacgc ggaatcaatt gtgtcaaagt cgttttcccg cttccggttg gaccaatgat
    67921 tccaaggact gtatttcgct tcagctgaaa tgtaatattt tggagagaaa gaccagaatc
    67981 aggagtataa cggaagtcaa catggtcaaa agcgataatt gcttcagaag aaaaatcggg
    68041 agtagtactg acctcagctt caagaatcga attttctgtg tctagcacct ctttcacccg
    68101 atttcctgaa gcttcggcac gtgtgaagat cacgacgagg tttgaaacaa cgatcagtgc
    68161 caaaagcatt tgattcatat aattgatcaa agcaagaact tgtccttgtt gcaagctacc
    68221 aatatttact ttgatcccgc caactgtcag caaacagatg atcccgacat tcatgatcaa
    68281 ggttgtagca ggtgataata gggcagagat attggaaaca cgtaaataat tgttcgctag
    68341 atcatttgtg cttttatcga acttctctgt ttcttttttt gtctgcgcaa atgcgcggat
    68401 gacacgaaca ccgctaagat tctgactaac gtgttcattg agctgatcta gtttttcttg
    68461 cactttttgg tagagaggaa cggttttttt gatgataaaa aataaaatga ttgagaaaat
    68521 aggcaataat gctaagaaaa acagacctac ttcccagtcg atcacaaaag ccatgaccac
    68581 tgacccgata cttaaaaacg gtgctctgat caataaacga atgaccattg ctaaagctag
    68641 ctgaagctga ttgatgtcgt ttgtcattcg ggtgatcaag gtatctgttc caaaatgatt
    68701 caactcgttg tgagagaaag tattgatttt tttgattagc tgattacgta actctgtacc
    68761 aaatccttgt gaagctactg aagcatagta ttggcaaatg atagcacaaa tcagaccaat
    68821 cacagacata gcgaccatcc ataagcccat ttcaatgatt tttcctcggt cattcatttt
    68881 tagtccatta tcgatcaagg aagccatcat taaaggcagg acaagttcga agacagcttc
    68941 aagaaatttg aagaacgggc ccaaaatgat ttgcttacga tagtcttttg cataacgtaa
    69001 taactgaatc atatgattcc tcctattatt tatttgtcca caattgaaaa aacaagtact
    69061 accacattgt agcttaggaa atttagaatg aaaagagaac aagccttttc ataaatgaaa
    69121 gttttattat gaagaagctt tagaaattga atagactatt ttttttaaaa aaaagaaaat
    69181 gagaaaacat gccagtctct tcattcatag gaacgtctat tttacttaat ttttctataa
    69241 atgaattctg cataaaaaat atatcaagta aatgtttata gatgaaactc tatttacttc
    69301 ttttttaatt tgttcttgca atcttttttg ctacgtaatt tttgtaaaaa agtgggttga
    69361 gagaaatcta attgattttc aaagaaggag tatgaaaatg agaaaaatat ttattcgttt
    69421 attgtgggta ctatcttaga ggaataaata atagtggaga aaactatggt ttggcgcaga
    69481 ttctatcagg tttgatggaa cgaagacaac ctcccgacat caagtcaaaa gccacttgag
    69541 attttgatct gaaaataaaa aaagaaaaca aggtaggaac atcaatgttt ctaccttgtt
    69601 ttcgtaatca atgggaaaaa actaagagtg gtgtacgtaa tcaataaaaa ggatggtgac
    69661 aacagtacct ctttactctc tgaaagcatc ataactcgtt tttcctcatt atgccaataa
    69721 attgttgtta taccacatat aaggatttgt aatagctaaa aacagacagg aaagttgaaa
    69781 tctgtgaatc ttattttgta tggaaggatt tatagaacgc aaaaatcaag ataaagatga
    69841 ataaaaatcc tgtttcggct atatattgcg tatctacgcc aataaaacga gtttgttctg
    69901 tcatagccat ataaagcaaa ggcaaaaata caactacagc gagataagat ccgatgattt
    69961 ctcgaaaagt tttccaggaa gtatgtttcc tgtttttata tttatccgat ttcattgaat
    70021 agtcatagcc tccttattct ttcatatgtt gaaattccag tataaaaact ggaaggaact
    70081 gtacgttttt tagaataaaa attataaggg ataagtaggc tgctgtctat aataagatat
    70141 atttttcaat tctttattaa agattttatt gacaaaatga atccgttttc tatgatggag
    70201 gaggggtgaa taagttgttg aagaaggaaa ttttatgtta cttagagaac cagacagcct
    70261 ttttcgattt agaacatatg aacgaggtct ttacagcaca aaggttagct gatcattttg
    70321 gggtaaaaag aaacacagtc agtcattatt tgaaccagtt aaatgatgag caactactag
    70381 tcaaaatcaa ttctcgacca gtgatttatt tccacaaaga agcttttgaa aaacaatttt
    70441 ttaagttacg cacgaatttt tatttttcta tcgatgatct caaagaggaa cagccttttt
    70501 tcgcgcaacc aaaagactta ttctctttta tgatcggata cgacgccagt ttgaaagaaa
    70561 gtatcgaaca aatcaaaaca gctctttact atccagatgg cggattacca cttttgatta
    70621 caggcgaaag tggcacaggt aaaagttatt tagttaattt ggtctatcag tattgtctgc
    70681 ttcatgatct gctagaagat tctgcaccat tcatcacttt taattgtgca caatatgcag
    70741 ataatcctga acttttgact agcaatttgt ttggacatgt taagggagcg tacactggtg
    70801 cagaagaaaa taaaaaaggg gcttttgaag cagcagatgg tgggatcttg tttttagacg
    70861 aggtacatcg cttaacacca gaaggtcagg aaaaactgtt cacctatctt gatcaaggtg
    70921 tgatttatcg tatgggagaa cctaatttgt cacgccggat caaaacacgt ctcttttttg
    70981 ctacgactga agagattact agtcatttct taacaacttt cattcgaaga atacctatcc
    71041 gaatcgaact acctgcactt aatcagcgta gtcgtaatga acggctagaa ctgatttact
    71101 ctttttttct cgaagaacaa agaaaaatgg ggagcccttt gtcagtcagt ggaccagctt
    71161 tgtcactttt aacaagtcag aaattatccg gaaacatagg agagctgaaa aatatcgtca
    71221 aagtttcagc agcaaaagca tatgctgaac agcgtgaaca gcctgaaatc catgtcacga
    71281 tccatcattt gcaaaaagaa ctacttgcgc agcctattac taaaaataca gcacagcaag
    71341 gaatctatat tacgcaagac cagaccttag agcaattaat ggagaagcaa cagcccgaac
    71401 agcagcgaat cgttaaaagt tttgagcaaa tcctaattga tttcaagaaa aataactgtc
    71461 tgctatattc ttgcgaagga aaattaaagc aagaagtgat tcaattattt gattttttgc
    71521 tgtttgagac cagtagacaa gaaaaacacg agctgctggt ttattggaca caatctatcc
    71581 gagagacctt tcgacaaatg gaaactgcct atcaaatcaa attcgatgga aacagtgtct
    71641 atgccttgag ttactatctc tatcagcgaa gcactatcaa atggttaccg gaagaacatg
    71701 atattatcca actaatcaaa gaattagaac aacaagtttc tcagtcttat ccatctagtt
    71761 atcactatgt ccaacgaatt ctggaattaa gtaagatcaa attagatatt gaagacacaa
    71821 gtatggatcg gattttactg acgatctatc taaaaaaagc gaaatggtca aaagaaaaac
    71881 gactgccaaa agcgatgatt gctgctcacg gttatgcaac tgctagcagt atggcaaatg
    71941 tagtaaatcg tttattacaa gaggatctat ttgaatcatt tgatatgcca ctagatgtca
    72001 caccacagca gattgcttca gaaatccttg attattgcga aaacagcgat gtttcaaatg
    72061 gattgatcat attagtagac atgggatctc tgaaagaaat ccatcagttt tttaaaaaac
    72121 agttatccgt accgcttttg attttgaata atgtgacgac acctttagca atcacagtag
    72181 gggaatgcct gcaaaaaaat gtatcattag aagagatagc agaagagact gttcgacaga
    72241 tccagccaga atggcgactg ctctatccag aggaaaacaa acccaaagca ctcattacta
    72301 cttgcttcac tggaatcggt acggcggtcc acttaagtga actgctagaa aaaagcttac
    72361 ctacggcttg tcagttgaaa atcatcccat atgaatatca gcaattaaaa gataagaaaa
    72421 acagtgaccc attattttcc atatacgaag tcgtaggaat gattggcacc acagatcctg
    72481 atatcaccaa tatcgactat ctttcattag aagacctcat ctcgggggaa aagatgtctg
    72541 tactagctga atggttggac actactatga atgcttcaga gaaggaaata ttcaatcagc
    72601 gcatcattcg taatttttca ttggaaaaag tactggattc cgtgactatt ctagatacag
    72661 agaaggtgat gggagaaatc gatcatttta tgagagaatt agaggtgcag ttgaatcgaa
    72721 gcatcagcaa tcccaaaaaa ttagcgttgt atgtccatgt gagctgtctc attgaacgat
    72781 tgatccgaca aatgccaatc gaaacctatc aaggattaga gaaatggaag cagtgtcaaa
    72841 aagaagggtt atctgctatt aaatctgcgt ttagtgtcat tgaagagcat tatagtgtca
    72901 tgatccccaa ttctgagatt gcctatatct atgatatttt gagtgaagat acagagtttc
    72961 tctcgataga agaagaattt tgaacataag caagttgttg ccactaattt tggcatgcaa
    73021 cttgcttttt tagtatgtgt aagtgaaaag aggagatgaa aaagtggata gagaaattat
    73081 cttagcttcc catggaaaat ttgcttcagg gatattagat tcattagagc tgatctatgg
    73141 gaaaaatcat tctattactg tattcgattg ctatactgat gagaattttg atttagcgga
    73201 aacagtaagg cagcttttta tgaggtacaa agataaagaa atcattgttc tgacggatct
    73261 ttttggcgga agtgtcaaca acgaattctt acaatatatc aatcgggatc atgtctatct
    73321 cgttgccgga ttgaatttgc cactattgat tgagctagta tctcggttgg acgctgaagt
    73381 agagacaact gttttgatcc agcaggtgct aactgattca aaaaaaatga tccagttttg
    73441 taacgagcgg ctcaatcaga aaatagaaga agacgaattt taggaggaag aaaaatgatt
    73501 gtattgacaa gagtcgacca tcggttatta cacggacaag tagctttttc atggacacaa
    73561 acaataggcg cagactgtat tttgattgct aatgatgatg tacctacgaa tgagatacga
    73621 aagacaacga tcaaattagc caagccacaa ggagtcaaac tagtgatcaa atcaattgat
    73681 gactcgattg ccgcgttgaa aagcggggtg acagataaat ataagttatt catcgtagtg
    73741 gaatcgatcg aggatgcata taagctggca gaagcgtatc cagaaatcaa aaccatcaac
    73801 ttaggaggga tcaaggcaaa acctggtact cgcagcatcg gaaaagcggt aaatatttta
    73861 ccagaagagg aggaacgctt gaaacgatta attgacaaac aaatagaagt agaaatccgt
    73921 caagtaccag cagataaaaa agtggatgta agagaagttt tgtaagaaag gaagaacctc
    73981 aatgattgta caagcagtct tattaggaat tgttgcattt gtcgcacaat cagaatatgc
    74041 actagggaca tcgttgcttt ctcgtccgat tgtgacgggg ctgtttacag gaatcgtgtt
    74101 aggtgatgta aaaactggga tcattatggg cgcaacttta gagttagcat ttatcggatc
    74161 gttctcagta ggtgcttcga ttccacctga tgttgtgacc ggtgggattt tagggacggc
    74221 ttttgctatt acagctggag ccggtacaga aaccgcgctt ttactaggtt tgccgattgc
    74281 tacgttgaca ttgatattga aaaatattta cttagggctt ttgattccaa ttatgaacca
    74341 taaagcagac aattatgcag aagaaggaaa ttataaagga gtcgagcata tgcacttgct
    74401 tgccggtatc ggtctttcct tgatgcttgg tgttgtggta atggtttctt atatggtggg
    74461 aagcaatacg atcggaaatc tattaaatat gattcctgac ttcgttcaaa aggggttgtc
    74521 agtagctaca gggttgattc cagctcttgg ttttgcgatg cttgctcgtt tgctgatcaa
    74581 caaacaagtt gcaccatatt ttttcttagg ttttgctata gcttcttact tagagattcc
    74641 tgtgaccgga gtagctattt ttggtgcgat tttagcagtt gtggtagtca atattatgaa
    74701 tgtccgtcaa ctaccacttc aaacaactgc aggggaggta gaagaagatg aagaattctg
    74761 agatcaaaaa cagcaaaata acgaaaaaag agctaaatca cgtattttgg cgttcttttc
    74821 aaatggagtt ttcttggaat tatgaacgtc agatgaatat ggcttatgtt tatgcaatga
    74881 ttccgatttt gaaaaagtta tatcagtcga aagaagaaat ggcagcagct ttgaaacggc
    74941 atctagagtt ttttaacacg accccacata tcgttacact gattttagga atcacggctg
    75001 caatggagga agaaaataag gatgatcctg aatttgatgt gactgcgatc gatagtatca
    75061 aaacatcttt gatgggacct cttgcagggt taggagattc tttcttttgg ggaactttgc
    75121 gattgattgc cacaggtgtg ggtacctctt tagccatgca aggaaatatt ttaggcccta
    75181 tcttgttcat tttgattttc aatattccgc acattctgtt tcgctatcta gcaacaggtt
    75241 ggggatatcg cttaggaacg ggttttttga aaaagatcca ggcaaacggt atgatggaaa
    75301 gtttgacatt aggcgcgtct attattggac tgatggtcgt tggagcaatg actgccacga
    75361 tgatcaccat caatattcct ttaaaaatcg gttcaggaga aaatgctgtg actgttcaaa
    75421 gtatttttga tgatatcgtt ccaaatatct tatgtcttgg agcatttggc atagtgtttt
    75481 atctattgaa gaaagaagtg aaaccattaa cgatcttgat cggactagct ttctttggaa
    75541 tttttggttc gtggataggg attttttaaa aaaggagcag agaaaatgtt tacgatgcaa
    75601 gattatatct atgaagaaaa ggaagtacta agtacgatct tgaaaaagaa tgatttttcg
    75661 acaagagaac atatgaaaaa aacagtgaat ttactgatct tagcaacggg ttcatcttat
    75721 aacgcttgtt tagcagcgaa gccagcattg gaatcttatg gtgatcttac tgtcgatatt
    75781 caagaacctt tttatttttt caattatgga aaactttctc cttcaatcga tactgtgatt
    75841 gctgtgtcac aaagcgggaa aagtgcttct actgttgaag cagtaaaaat gatacaaaaa
    75901 caagggttac ctgttgttgc tatcacaaat gacgtgcaaa gtccacttgc tttagaagct
    75961 gcacaaatta ttgatttagg tgccggggta gaatcagtag gcttcgttac aaaaggctat
    76021 tctgcgactg ttttacagtt actactctta gggataggaa ttggaataag taaaaataaa
    76081 atcagcaaaa aaatagaaca agactacatg caacagttgc gcaaaataat caaccattta
    76141 ccagcgatta ttcaaaaaac ggaagaattt tttgatggat atcaaagttt atttcgttta
    76201 gcacagcgtt tcgtcaccat tggatatggt ccaaactggg gaacagctaa agaagcagag
    76261 acgaaattga ctgaaacaat ccgcgttccg tcacaaggat ttgagttaga agcttatatg
    76321 cacggcccat acctggaggc agatgcttcg catttgctat tctttattga aggggaaagt
    76381 gtaaataagg aacgttcgca aaagttgcaa agatatatga gtcggtacgt tggagagact
    76441 ctcaccatta ccacaaaaaa agcaagaaac gagaaaacac ttggattagc aatagaatgt
    76501 gatgaatatc tgtctgtatt agcgcttgtc gttccgtttc aactattcgc ttataaaacc
    76561 gcagtagcta aaggtattga cttgaacaaa aagatttttg aagactttga tacagtcttg
    76621 aaaagtaaat tataagaggt ggaaatcatg ctgaaattca atgaagaaga acaaatcaaa
    76681 gcaataaaag gcgcactagc tttacgtccg caagtagaag aaatcatcga taaactttat
    76741 gcggaaaaat ttgacgctgt ctattatcta ggaatcggtg gaacgtatgc ttcctcgatg
    76801 caagctgtca cttatatgaa tgggaaaagc aacttgcctg tctttgtaca gcatgctgca
    76861 gaatattaca ctactggaaa caaaagatta acaaaagatt ctatcgttat tttgtcctct
    76921 gttaccggta caactcaaga agtagtgaaa gcagtagaac aaatcaagaa agtaggagcg
    76981 acactgattg gatttatcga taaagcgaac agtaagttgt ctcagctatg cgattttgtg
    77041 gtcacttatc cagctcctgg aacagaacaa atcaaatttt ttatggcagc agatcgattg
    77101 atgtatttga atggagaatt cgaagcttat tcagaatact atgaacagct cgaacgttat
    77161 ttaccaacag ggttagtgga agcagagaaa aaagcagatg catttggctt atcatttgca
    77221 gaaaaacatc gacgtgatag tatgcattat tttattggag cagggaatca atggggagct
    77281 gtttattcat atgccatgtg ttactgggaa gaacaaagct ggcttccatc gaaatctatc
    77341 catgctgccg agtttcttca cgggacgtta gagatcgtag aagaaacaac cccagtcaca
    77401 ttatttttag gcgaagatga acagagagtg ttatctgaac gtgtggctaa acttttgcca
    77461 aaaatttgca gcaattatac attgatagac acaaaagact atccagtaga aggtatcagt
    77521 gaaaaatatc gcggacgtgt tttgtctttc ttattgatgc atgtagtgac acaacgcatc
    77581 gatgctcatg tggagcagtt gaactgccat ccattagaga tacgccgcta ctatcgtcag
    77641 tttgattatt aggatagact ggataaaaag aatataaaaa ataaagagag cagcgataac
    77701 tgctcccttt atttttttaa aatattggca tcaattacgt tataaaacac attttttgca
    77761 ttatctacag ttcaacttat aatctgttta atgggacatg tgggtgccaa ccattttttg
    77821 ttatgcaata gtactattta gttgttgcat ggatccgtag taaaagtcca agtacaacga
    77881 gttgcgccag tttacatagc gttttgtatc cagaatgttg actaaaacaa aagttcctat
    77941 gtcaaccgtc aacagagaca atctgtccgt tgcaggacct gacagattta gaaatgttca
    78001 atctgtctct tatgtatttt aaatcaatac tcactaggag aagtttccta acctcctaat
    78061 agtaatgctg gtagtaacat tgtcaaaact gcttcctctt aggaacaagc aaagcataac
    78121 gagtgtaaaa ataaaatgta gactattgta acatatcatt gattatttca agtaaaaacg
    78181 ataaaagaag taaacaaaca cttaaaaaca atggaaatta gtcccaactt taagaaatgt
    78241 atactataat ggaaattatc aattatttat ttggaggaat atccatgaaa caaaaaatcg
    78301 cagttcttgg tcctggatct tggggcactg ctttagcaca aacattggca gaaaacgggc
    78361 atgatgtccg tatttgggga aatgtacctg aacagattga tgaaatcaat aagtatcata
    78421 caaatcagca ttttttacct gatttgacga tcccagaatc gattatcgga tataaagaat
    78481 tggcagaagc agtggataac gcagatgcta ttttatttgt tgttccaaca aaagcgattc
    78541 gttcagtcgc acaggaactt attggtaaaa tgaatactaa gccaatcatt atacatgcaa
    78601 gtaaaggact agaacaagat acgcataaac gaatctcaga agttttggct gaagaaattc
    78661 cagaagaaaa aagacaggca attgttgtat tatctggtcc tagccatgct gaggaagtgg
    78721 cagtacatga tatcacaaca attacagctg caagtattga tcaaaaagca gcagcctatg
    78781 tacaaaaact gttcatgaat gattatttca ggatttatac aaataatgat gtgattggcg
    78841 tagaaactgg tgcagcactg aaaaatatca ttgcaattgg tgccggcgct atccatggat
    78901 taggattcgg agatgatgca aaagcagcaa tcatgactcg aggattggca gaaatcagcc
    78961 gtcttggtgt cgcgatgggt gccaatcctc tgacatttat cggtttgagt ggtgtggggg
    79021 acttgatcgt tacttgtaca agtgttcatt ctcgcaattg gcgtgccggt aacttgttag
    79081 gacagggaca taagctggaa gaagttctag aaaacatggg aatggtcgtt gagggtgtgg
    79141 caacgacaaa agcagcagta gagctagctc aacagctagg tgttgagatg ccaattactc
    79201 aaacaatcta taatgttttg tataatggag aagatatcaa aaaagcagca aaagaaatca
    79261 tgttacgtga cggaaaaatg gagaatgaat tttctcttcg ttaaatagat gatcaatagt
    79321 taatcgtcgt ttaggaggaa cagcaagtga aggtcaaaaa agcagtcatt cctgccgctg
    79381 ggctaggaac acgttttttg ccggcaacaa aagccatggc aaaagaaatg cttccaatcg
    79441 tggataaacc aacgatccag tttattgtgg aagaagcatt ggattcggga atcgaagaca
    79501 tcttgatcgt aacgggaaaa gaaaaaagac ccattgaaga tcactttgat gcaaatatcg
    79561 aattggaaaa caatttgcgg gaaaaggaaa aaacagaatt actcgcttta gttgaagaaa
    79621 cgactcaagt caatcttcac ttcatccgtc aatctcatcc aagaggactg ggggatgccg
    79681 tgcttcaagc aaaagcattt ataggaaatg aaccgtttgt cgtcatgctg ggggatgatt
    79741 tgatgaaaga tgatatccca ttgactcaac aattgatgat ggattatgaa gaaacacaag
    79801 cttccgctgt tgccgtcatg cgtgtaccag aaaatgaaac atctaaatac ggaattattg
    79861 atcctaaaac agatagcgaa aagggtcgtt gcagagtaaa agggtttgta gaaaaacctg
    79921 aaatgggaaa agcaccaagt aatttagcca ttatcggacg ttatctactg actcctaaaa
    79981 tatttgagat attagaaact caagaaccag gagcaggaaa cgagatacag ctaacggatg
    80041 cacttcagac tcttaaccag acagaggcgg tctatgcgag agagtttaaa ggaaaaagat
    80101 acgacgtagg cgataagtta ggatatatga agacaaatat tgaatatgga cttcaacatt
    80161 cggaaattgg gacttcatta agtgcatata ttatccagtt gagtaaaaag ctaagaacag
    80221 aaagttaact ggaaataagt ggcctgctga gaatgaaagg ctatttgtta ttaaagcggc
    80281 agcttgtgcg tcatttgcgc aactgtcgtt ttagtttttt gactctagat cagttgagtc
    80341 gtggaaaacg aaagatagaa aaagactttc gtgaatagat tcagaaaata ttatgctaat
    80401 ggtttaattt ttttttaagt tgtataaaag aaaatgatta cataagagaa atgaaagcca
    80461 agccagaaga ttcatagtag aataaaaagg cgaatttttt aattataaaa aaaggtgtgt
    80521 gttcactatg ggaaaattag tcgctgttgc acagtcgctg cttgatatac tcaagtggct
    80581 gatggaagga agcaattgga tatttgtgtt gccactattg cttattagtc tatttatcat
    80641 gtttcgcatg gtcagaaaaa aagaaacgtt tctgattttt atctggtatg cagcatccgt
    80701 tggggttgct accttgatgg ttgaattggc gttaggtagt tgggaagctt gcgtatttgc
    80761 tttatttttt gctgtactgt atctaatcat ttatatccca tatatgaaaa gaaagtctcg
    80821 gataggcaga aaaggtagac atacaactac tttttctagt acagattctc tcgaacaaag
    80881 tagaagaacg agaagaagac ggtaatattt agtaggtata cgcaaaaaaa gataaaataa
    80941 tggataaact attgagatga gagatttatt taattggtgg aaaaaagctt ttttcactta
    81001 tataaaagaa tcttttttaa aggaatgctt gttgtatcgg gataagccat tccttttttt
    81061 atgttattta tatatatata aatcatacca atgttttttt gtattttctt gcttgcactt
    81121 ggataagaga ttacttacaa taaattcaga tagaaacagc tgaataaaaa aaggctccct
    81181 gacccttagt tggcgctaag aatcagggaa tgaccagtca cacacataca ccctgaccga
    81241 tcattttgcc atagtcaatg cagtgcatcg acctaattta ttgtacctaa tctagggtga
    81301 aaattctacc cctatgtaga tattttccat ggtctgcacg ttgttttatt tgctatgtca
    81361 aggtattggg cgtattcgtt caatgccttt tttgtgtttg aaacagcaaa gaccacatgt
    81421 gttactgtct aactactgtt tttttatgta cttccttaga ttaggcagct gtttctattc
    81481 atgtcaagta tagctaggcg ggagagataa atgagtttat gttattttga ctattatcac
    81541 caattggaag agaaattaag gatagaagag ccgctgatgc ttcaagctgg cacttggatc
    81601 gcgaaacaaa ttaatcaagg tggtagattg cagatatatg ctagccgcac actaagtggt
    81661 gtagcatttg aattttggga tcaaaccccg gatcttgtac caagtatatt gattgaaaat
    81721 ccagccggag gtgtctatga aacgctagaa ggtgcaggac aggcaattat tgatcagctt
    81781 tctgtcaaat cagaagacat ttttcttctt ctttcgaatg aaggaagaaa cccggcaatc
    81841 atcgaactag ctcagtggat caaagaaaat ggtcatccat taatcattgt tactggattt
    81901 gatttgtcac gaagtatcaa atcgcaacat agcagtggtt tgcgattatt tgaatttgct
    81961 gatttggttt tggacaacca cgccaattta catgatgcag tcttgacttt gccaaatcta
    82021 gatccagcga tctgcggaac agcctctctt gcaacgatct ttttgctgca gcaagttttg
    82081 tattttacag caaaacagct agtccaggac acaagtggaa aatagttatc cacatgttga
    82141 caaagttcct taaaaaaata atgttccaca taaaaatgga gcgtttgaaa aaaagaaaac
    82201 gattattaat gaggattaac aacgactact ttttttgttt tagttatttt aagatggatc
    82261 atctttgatt ttaagcttgt tttgtttaaa gtttgttatt tttataagtt gtttcacagt
    82321 tatgagaaat gagttataag aatatgtagt gtcagaaaaa taaaaagtag tggaaaaaga
    82381 gacaagaaag aatccatatg gattctttct tgtctcttaa tacacgttga tgaaagagtc
    82441 ttccccaaaa ctctttacaa agtaattata gtacatttgt tatcattatt gcaatgaagt
    82501 ttacctgata taacaaaatt gtccaacagg ataccttttt ctaatagaaa taaaatacac
    82561 aaaaattgaa ggatagataa tggatattta taagtgttta ttattttttt tgcaatgaaa
    82621 ttcaattttt caatgattgt aaaatgaaaa aaacaggacg agattttctc taatctaaaa
    82681 ataaaaaaag aattttaagg aaaaacagag aaataaaata cttaatataa atggaaagag
    82741 aaaaaaataa tcatacatag gagaaaaaaa acaaaataga aaaaagtgat tttctaataa
    82801 attattcatg tggaaatgtc atttttactg tataattcat ttgattatcc attttttatt
    82861 catcaaaatt actgaaaaaa gaaaggaaga aataaatttg aagaaaacaa attcttcagg
    82921 aaaaccgaaa cgcgacttca ctaaattatc gacaccccat acgtatgtca ttatttttgg
    82981 tgtagtcatc tttgcatgga tactgacttt tgtcgttcca gcaggaaagt tcagcacgca
    83041 agatattgaa tacaaagatg caaatggcga aacaagtact cgtactgttt tacgtcaaga
    83101 ttccttccgt tatgcttacg agctggataa gtcgtatgtg tttgatcaat tagaagaact
    83161 gcaagatcat ccagcagaac gtgaaaaact ggatgttccg gaaaaaggat tggaaaaagt
    83221 cattgctgac ggagaaaaaa atcttacgca ggaaaaacta gatgaaatct ccttgacaga
    83281 tgatgtgctt tacgatcagt acggcgaaaa tatctatgat acttctaaaa aattgcataa
    83341 aacagccaaa atatggggaa cagatgattt tggcggcttt ggtttcttaa attttgtttt
    83401 tgaaggacta gtatctggag ataagtatgg atctgctgta gggatcgctg cattgatcct
    83461 tgttgttgga ggtgcttttg gtattattat gcgtaccgga gcgatcgacg caggtatcta
    83521 tgcgtttatc agtaaaacta agggactgga gcgtttagct ttaccgctat tattctttgc
    83581 tttttcattc ggtggcgcta cattcgggat ggcagaagag gtaattccat tctcaatggt
    83641 gatggttcca tttgtcattg cgttaggata tgactcgatc gtagcagtaa ccgtgactta
    83701 tgtcgcatct caagtcggaa atgcgacctc ttggatgagc ccgtttagcg tagcggtggc
    83761 tcaagggatt gctggaatcc ccgtgttgtc tggtgcgaca ttccgattga ttatgtgggt
    83821 agttgttact gcattagccg ctggttatat gatgatatat gcagaaaaaa tccgtaaaaa
    83881 accagaaagt tcgttgactt acaaatcaga tgattatttc cgttctcata tcaaaaagac
    83941 atctgatgaa aataaaaaat tcatgcttgg gcataaattg atcttattag agatgttagt
    84001 tgtccttgtc tggatcgttt ggggcgtgac tcaaaaaggc tattacattc cagaaatcgc
    84061 ttctcaattc tttgtgatgg gattagttgc tggaatcatt gctgttcttt tcaaattaga
    84121 tggaatgaaa gtcaatgaca tcgcttcttc tttccaatct ggtgcagctg atttagctgg
    84181 tacagcaatc gtagtaggta tggccaaagg gattcttctt gtcttgggag gatctgatgc
    84241 atctgttcct tcagctttga atacgatttt gcatgggatc gggacggcgt tgaccggtgt
    84301 tccagctgtc attggtgctt gggcgatgta catcttccaa agtttgttca acttggttgt
    84361 tacatcaaat tcaggacaag cagctttgac tatgccaatc atggctccac tggcagattt
    84421 agtaggtgta tccagacaag tagcagttct tgcttatcag cttggttcag gttttatgga
    84481 cgcttttaca cccgtatcag ccagcttgat tggtgtgcta ggtgttgcac ggatcgaatg
    84541 ggcaaaatgg gcaagattcc aaatcaagat gcaaggattc ctgtttgttt taggaactat
    84601 tttcatcatg attgccattg caataggtct gcagtagtac tggagacctg taaataaaaa
    84661 agtaatccaa acagtagata aggactccaa gaaccgtcat tttacggtaa aatcaaagga
    84721 gtaaagatcc tatcgtttgg attatttttt aagatcctat catcagttat acttaaagaa
    84781 agaggaaaaa tgtatgaaaa tcattcgaca aattgaagtg tttgcaccag attacttagg
    84841 aaaaatggat gtactgattg ccggtgggaa gattttggct gtagaagaac agctagaagg
    84901 cggctacgaa ggagtggaag tagaagaact ttcaggtgag ggaaaagtac taaccccggg
    84961 tttcattgac tgtcatttcc atattttagg tggaggagga gaaggcggtt atcaaaatcg
    85021 aacgccagaa gtcacattga gccaattgac tacagctggt gtaacgacag ttgtcggttg
    85081 tttgggaaca gacggagaag gtagagatat gactgcgttg atcagcaaag cgaaaggtct
    85141 ggaagcagaa ggaatctcca cttatgtata cgaaggttcg taccgattgc cggtaaaaac
    85201 agtaacagat tctatcatca aagacttttt gacaattgat aaaattatcg gaatcggaga
    85261 aatcgcagta tccgatcacc gttcttctca gccaagtttt gaagagttcg ctcgtgcagt
    85321 agcagatgct cgtgtaggag gcatgttatc cggaaaagct gggatcatca atgtccactt
    85381 aggcggagga aaaagaaagc tagagctatt gacacgaatc gtagaagaaa cagaaattcc
    85441 gatcacacaa tttttgccta ctcatgcaaa tcgcacacca gaattatttg aagcttgcgt
    85501 ggcatttgcc aaacgtggtg gcacgattga cttcactgct agcgaagatc ctgatttttg
    85561 ggagaagaca gatggtgaag ttcgcttcag caaagcactg aaacgattga tcgaggaaga
    85621 tgtttcttta gataatttca cgatgacctc agatggacaa ggaagcttgc cttattttga
    85681 tgaaaacaat catttcctag ggttaggagt aggaagtgcc aaggcattgc tagtagggat
    85741 caaagaagct gtgcaaaaag aaagtatccc tttggaaatc gccttacgag ctataaccag
    85801 taatccagca cgtatattga aattggataa aaaaggaaaa atcgaaattg gtgctgatgc
    85861 agatctgtgt atcttggata aagaaacgct tgatattgat acagttatcg ctaaaggaga
    85921 aataatggtc caagaaaaag aagtcaaagt atgggggact ttcgaaaaaa gtttttaatc
    85981 aacagctcta actatctttt ttagaaaacg agcgttctgt ttgtctgtat ctgttgttga
    86041 tgttaccctg aaggtagatc aataaacaaa ctaagaggag gaagcacaat ggcagattta
    86101 aaaggacgtt ctaaagatat gaaagataaa gtagtcggtg aaggaaaaga agcatacggc
    86161 aaagcaacag acgacaagag caaagaaaca gaagggaaag cacaatcact aggtgctgac
    86221 atcaaagaaa aagctcgaaa tttaggcgac gaagtcaaag acaagttttc tcgaaaagac
    86281 gaaaaaaaat aaaaaccact tattactaat tgaatcaagc aaataaaaaa tccgaaccat
    86341 atctgcgaga cagatatggt tcggattttt tatttgatca ttatcctgtt ttttaaactt
    86401 cgattttttg aaatttttta ttttttagtt caaagacttc atcacagctt tttgctactt
    86461 caatctcatg agtcacgatg ataatacagc gattttgttc atgggcgatt tcttggaaaa
    86521 gtttgacgat atcttgtgaa gttgtttcat ctagatttcc agtaggctca tccgctacga
    86581 ttagttgatg ttcacagcag atagcacgaa cgatagcgac tcgctgctgc tgacctcccg
    86641 aaagtttggt cacctgtttt tttgctaata tttcatcaat tcctacacga gccagtcgat
    86701 ctaaagcaac ttgtcgataa ttctcttgct tggtcttagt gatttccatt gctgctatga
    86761 cgttgtctag agccgataaa taaggaagca agttgtaagc ttggaaaata atcgagacat
    86821 catttttacg ataacttctt aacccgattt tgttcagtga acgatcttga tagtatacct
    86881 ttccttcttt tggtgcatct agtccagaaa taagcgaaag aaaagtcgtt tttccagaac
    86941 cacttgctcc taaaatagcg tacatttttc cagcttcgaa attcagttct acatctttat
    87001 aaagcgcatc ttgcggatct tgataccaaa atcccaattg ttctgtccgt aacatcaaat
    87061 tcctccttta gtttaatagg atttttcttg ggtttaatct taatatccct atagaagcta
    87121 aaaagacaga aaacagactg attccaaatg ctactccggc taatagtccc aattgtgcag
    87181 gtttgacatt gatttccaat tcgctgactt gatcagaaac agcaaatgga ttattcgtgg
    87241 ttccttgttg accatcgcgt tgaccgcctt gttcttgtct gttacctggc atttgtccac
    87301 cgccaggagc ttgctggttt tgtgtcgtgg tttctgtctg ttggtcaagt agctgctgtc
    87361 ccacggcatt cgcgacgacg tttccgctaa gcgaagcaac tcctaatgca agaatcatac
    87421 aaatagccac ttcggtaaac aattggagaa tgattttact tctggattct cctaaagata
    87481 gcaagacgcc taactcatgc cgacgctccc gaatggtaat cataatgatc agagtaagta
    87541 tgataatacc ggctacagcc actagtaaaa caacattttt agaaaaactt gccacgttgt
    87601 ttaaaggttc caacattgac tgatacatgg aatcatttga ttgtaagcta aatgtatctg
    87661 tgtcgatcag cttctcagct tctttgagaa actcatccat tttatctgga tcagatagag
    87721 tgtaaatagc agaatctatc gtgttatcgt cagatgtccc atttagttca tttgcaaaag
    87781 tgtaagaagt gtaaagtgta ttcgacggat tcatgaagtt gaatttcata cccatactgc
    87841 cgcttgtttc gctggattca taaattcctt tgatcgtcat ttcataagtg gtatcttcat
    87901 cttcagtact cgtgattgtg aaagtatctc cgactgccag gtcatttgtt tctgctagag
    87961 tagaatcaat gactacattg tttgtgcctt tgtcgctgtc atctattcct tcaccatccg
    88021 tgatttttgc tgttccatca gaaaaattac tattttgtgc agttgctgac acaccactga
    88081 tttgaaagtc tgcttgagtc atttgcggat tcccgcccat tcctccagca ggttcaccgc
    88141 ctgcatcagt agtttctgaa ctgtcttcac ttgaatcaga actagtgatg gcagttattc
    88201 catcttttgc catagctgag gcggaacttt caaaggaata actctttaca ttatctaatt
    88261 cagctatttt ttccgcgtcc gttaaggaaa ctggtgtaag agaaaaactg cctggatctg
    88321 gacgttcttc agtggtagaa ccgcttgaag aagtttgttc ctgtttttta aatgaagctt
    88381 ctcgattggc acttaaagtc actgttgctc caacttcttt ttgtgcttga ttcgctgctt
    88441 cttctgcagc gcttcgaatc gtgaggccag ctagcacaaa aataagaatg gctgtgaaca
    88501 cggcaaacaa taacaatgaa cgtccccatt ttacttttgt acttttccat gcacgtttca
    88561 taaaattcat attttgcatc cctcctagta gatgcatttg ataatagaca acctatctta
    88621 aagctagctt aaatcttatg ctgtttgcac accatcaaca tgaggttctg tatatataaa
    88681 aagtcactat agttattgca aaaaatgtgg taaaatgaaa aaagtatgtt tcaaaccgac
    88741 gaagaagaaa tgaaagagga atagcaaaag aaatcctaga tgctacagag ggatttttac
    88801 gtgcatagtt gttctaacaa ttgctgatac tagcgattta gtttatttgt tgtataataa
    88861 tggggaacag ctgaatactt atataagtat tctggctata gcgtttcgca aaagatccat
    88921 tttgttaatg aagtatatcc aaaataaaat gcccatccaa ctgtcagaac gcggatgtgc
    88981 tggtaatttt cctgctgatt ctccataagt tgagaaatag tgattttgca tatgcttcat
    89041 tggaatggct catatattta gataaagaag aaaatcgaca tctttaaact tggatgtcat
    89101 aagaagaggt gaagtttgtg agtaccatta aaattatccc attaggcggc gttcgtgaaa
    89161 atggaaaaaa catgtatgtc gcagaagtgg gcgaggatat ttttatttta gattgtgggc
    89221 taaaatatcc tgaaaatgag ttgttgggga tcgacgtcgt aatccctgat tttacgtatt
    89281 tagaagaaaa cattgatcgt gtagctggtg tctttttaac acatggacat gcagatgcga
    89341 tcggggcact tccttacttg ttgtcaaaaa tttctgtacc agtattcggg acagagttga
    89401 cgatcgagtt agcaaaattg aatgtcagtc gtaatgaagc agccaaagga tttaaggatt
    89461 tccatgtggt agatgagcat acagaaatag actttggtga aacagtagtg agctttttcc
    89521 gtaccactca tacgatacca gattcagtgg ggatcaatct gaaaacaaaa gaaggtagta
    89581 tcgtttatac gggagatttt aaatttgacc aaacggctat cccaatgtat caaacagatt
    89641 atgcacgatt ggcggaaatc ggcaaagaag gagtcttagc cttactaagt gaatcggcaa
    89701 atgcagaaaa tcctcagcct gtagcttctg aagcccaaat agcagatgaa gtatttgata
    89761 cgatcaaata ttgggaaggg cgtatcatcg tcgcttgtgt agcaagtaat ttgcaacgag
    89821 tgcaacaagt attggatgca gcagaaaaag cacaacgaaa agttgtcttg actggtcaag
    89881 atttcgaacg aattattcgc acagcgatgc gtttagaaaa acttcaatta ccaagtgaag
    89941 atctgcttgt tacgttgaaa gacatgaaaa actatgatcc agaagaactg atcattttag
    90001 aaactggccg aatgggtgaa cccatcaagt ctctgcaaaa aatggcaaac ggtacacacc
    90061 gtaatgtcaa gattgaagaa ggagatttgg tttatatcac tactacgcca agcatcgcga
    90121 tggaaaccat cgtggcgaaa acggaagata tcatttatcg agctggtgga acagtgaagt
    90181 tgatctctga gaatatgcgc gtttctggcc atgccaatcc taatgacttg caattaatga
    90241 tcaatttgat gaaaccaaca tattttgtgc cagttcaagg agagtatcgt gaattagctg
    90301 ctcatgcaga tttggctcat gcagtaggga tgccatacaa aaatatctat attactggac
    90361 gcggagacgt gctggaatat aagaacaagc gtatgagtgt tgcaggaact acaagtgcag
    90421 aaaatgtaat gattgatgga ttaggcatag gtgatatcgg aaacattgtt ttacgtgatc
    90481 gaaaaatctt gtcagaagac gggattttcg tagcggttgt cactatcagt cggcgagaaa
    90541 agaaaatcat ttcaaaacct caaattactt cacggggatt cgtttacgta aaagctagcc
    90601 gtgatctgat gaaagaaagc agcaatatga ttgaaacaat cgttgagaaa catttagaaa
    90661 gcaatgattt tgagtggagc aaattaaagc aagacatccg agatcaatta ggccgttact
    90721 tatttgaaca aacaaaacgc cgcccagtga tcttgccagt cattatggaa gctactcaac
    90781 gtcgaaataa aaaataaaca aaaagagtaa gatgaacctc tctatagagt gctcgtcttg
    90841 ctcttttttt gcgaaaaaca aataattttt gaatacagca tccctcgctt tataataaac
    90901 gatagaataa agggagtgaa tcaatgatga gtcaaacaaa agtcgaacgt tatttagaag
    90961 aacaaaagat cagctatcaa ccacttgatt ttagtcatgt ggtagaagaa tctttcacag
    91021 aagaactaca aaaaagaggg attgatccag ctttgatatg taaaactctc gtagtgaaag
    91081 gaaacaaaac tggggtgatc atcgcattga ttcctttgaa cgatcactta gattacaaaa
    91141 aaacgagaca agtgacgaaa gatcgtaaag ttggttttcc tggaatggat tttgtattaa
    91201 tgcatacagg atatccccac ggagcaaaca cccctattgg aataaaactc gcacatcctg
    91261 attattgttt tttagcagac agttctttaa aagaaaaaga agaagtaatt gtgtcaagcg
    91321 gtgaaatcgg gagaagcctt cggataaaag tagccgattt agaaaagatc gtccatccta
    91381 tttacgctga tttaattagt taagggacga gaagagaagc taagcagagc agagacctca
    91441 aacttgagat tatatctgct tggtacttgg tgcatcctgt attatctgtt acaattgctt
    91501 tgtacatact gtactatcaa tccaatgaaa atatatttag cagctatatt ttttcattga
    91561 tgtgcaagtg atgaaatcgt ttttaataaa aaagatacag agaaaacgcg aggtgtaaaa
    91621 tatgaaaatt acgtatcatg gacattcctg tttaacaatt gaaatggaaa atggccaacg
    91681 cgtgatgatt gacccgttta ttacaggaaa tccattgaca gacttaactg cagaagaagt
    91741 aaagacagat tggttgctga ttactcatgg tcatagtgac cacataggag atatgattcc
    91801 tattgcaaaa gaaaatcaag ccacaattat cagtattgtt gagattgctg attatgcgaa
    91861 cagcagagga gtagattcat tcggtatgaa tatcggtgga aaacatgcgt ttccattcgg
    91921 cgtggtaaaa ttcgtacatg cacagcatag ttcaagctat gaagtagacg gtatcgttca
    91981 gtatatgggc gagcctagcg gaattattat tcaagcagaa ggaaaaacga tttatcatgc
    92041 aggggatact gcttatttca gtgatctagg attgcttgca gaagaattcg atattgatgt
    92101 cgctttcttg ccgattggcg ataactatac gatggggcca gaagatgcag caaaggctgc
    92161 gcaaacaatt cgtgccaaga aagtagttcc aatccattac aatactttcc ctgtcattga
    92221 acaagatccc gaatcttttg tagagttact ggaagatagt gaaggaaaaa taatgagcgt
    92281 ctcggaaacg ctggaagtgt aggcagaaaa tggcgacaaa acatgatttg attttagaat
    92341 atattgaaag tttacctgtt ggcaatcgaa tttctgtaag aagcatcgca aaagaattga
    92401 atgtcagtga aggaacagcg taccgtgcaa tcaaagatgc agaaaatgtc ggactagttt
    92461 caacaattca acgagtaggg accatccgta tcgaacgcaa attaaaaaaa catattgaac
    92521 gtttgacatt tggcgaggtc gtcaggatca ttgaagggga cgttttaggc ggggcggcag
    92581 gattagacaa ggtcttgaat aaattcgtca tcggcgcgat gactaaacat gccatggaac
    92641 gctatattac gccaggatca ctaatgatcg tcggcaaccg ggcggaagtc caaaaattag
    92701 cattggaaga tggcgccgca gtattgatca caggaggatt caatacgact gctgagattg
    92761 caaagctagc tgatgatctt gaaatgccga tcttacgcac ctcttatgat acatttacag
    92821 tcgcaaccat gatcaaccga gcgttaagcg accaattgat caaaaaagat atcatgcttg
    92881 tcagtgatat ctatatgcca gctgaaaaga ctcattattt gcagcagaca gatacgattt
    92941 ctgattatca gcgtttgtca gaagaaacgc agcattcgcg ttttccagtc gtcaaccgcc
    93001 atcatcgttt gatggggatt gttacggcaa aagatgtttt agggaaatcg ccaaaccaga
    93061 tcatcgatcg ggtgatgacg aaagaaccaa tcagtgtaaa gaaaacaatg agtattgcct
    93121 ctgttagcca tcaaatgatc tgggatgggc tagaagtcat gccggtcgtt tccgatgact
    93181 tgacattgga aggcttgatt acccggcaag atgtaatgaa agcgatgcag cttgtccagc
    93241 gacaaccgca gattgcagat acgatttcgg atcagatatc tggaaatatc catacgattg
    93301 atactgaccg tgaaggaaat cgtttggaaa accctaagtt caaattcgta gtagcaccac
    93361 aaatggtcaa tggcgttgga accatttctt ttggcgtact tagcgaaatc atttctgatg
    93421 tcgcacaaaa aacaatggtg atgaaccaaa aacgaaatat cttgattgaa caagtgaacc
    93481 tacattattt gcggctgatc caattggaaa gcgaattaga cattcgtcca cgtgtattgg
    93541 aaatcggcag acgttccgct aaactggata tcgaagtgtt tattgaaaac accatcgttt
    93601 ccaaagcaat cgttgtttgt caagtaatgg aacgttctta gaaagcagga gtgaaatgac
    93661 agtacagcaa gaaatagtag atacaataaa aaaatacgat aaaatcatta tccacaggca
    93721 tttgcgccct gatcctgatg cattaggatc acaagtagga ttagccgaac tattacggga
    93781 aagtttccca gaaaaagaaa tacgtcaagt aggtgaaacg attgaagggc ttcgcttttt
    93841 agcagaaatg caagaagttg aagatgtctt ctaccaagga gcgctagtca tcgtgactga
    93901 tacagctaat tcacccagaa tcagtgatca aagatatcag ttggcagaaa aactgatcaa
    93961 aatcgaccat catcccaatg atgaccctta tggagatctt gtgtgggtaa atacaaaagc
    94021 aagtagctgt agtgagatga ttgcagaatt tgctttgatg tttcctgaat ctttaaagat
    94081 gaacgttaag gctgcacggt tactttatgc aggaatcgtc ggagatacag ggcgcttttt
    94141 gtatccctcc acgacgtccc gtacattaga gattgcttcg atattgagaa attatccatt
    94201 tgatgcaagt gctttgaaca gagagattga acaaatgccg atgaaagtcg ctaaactttc
    94261 cggttatctt tatcaaaata tccaggtgga tgaaaatggt gcaggaagaa taatccttcc
    94321 gcaagaaatt cttgataaat atggaatcga tgattcagag acagcttcga tcgtttcact
    94381 tcctggagtg attgacgaag tgctggcttg ggggattttt gttcagcagc cttcagggta
    94441 ttaccgcgta cgtttacgtt ctaaggggcc gatcatcaat gaattggcta aacgccatca
    94501 tggaggaggc catccattag caagtggtgc gaatgcaaaa gatttagcag aagtagagga
    94561 aatctataaa gagatccaag atatatgcca atcgtataag agcagaaaaa cagaatgata
    94621 cttcgttcga aaacgtgcct tttgtagtaa aaatcacaaa tgtatctttt caagatcttc
    94681 tttttccgtt acaatagtgc tcactaaaga ttttaaagga gaaagaagat gacattacca
    94741 aattgcccag aatgtggctc agagtacaca tatgaagatc gaggcttgtt gatttgccca
    94801 gaatgcggga acgaatggaa caaagaagaa caagaaactg tcatagaaga cggattagtg
    94861 gtattagatg caaatggaaa ccgtctgtta gagggcgata gcgtgacagt gattaaagac
    94921 ttgaaagtaa aaggtgcgtc aggtgccatt aaacaaggaa caaaagtcaa gaacatccgt
    94981 ttagtagaag gcgatcataa tatcgattgc aaggtagaag gatttggacc gatgaaactg
    95041 aaatcggaat ttgtgaaaaa gaattaaaga atattcaagg tcttttcaca ttcttttcct
    95101 actactaatg ataaaataaa gtaaacgaaa aggagtgaaa cgaaaatgta tggttatgga
    95161 atgtatggtt ttttagatcc gacatttctt ttggtcattc ttggattagt tatttccgga
    95221 attgcgtcag cgtacgtcaa tagtactttc cgaaaatacg atcaagtgag aagcaaaaac
    95281 aatgtgactg gtacacaagc agcacaatat atattacaaa gtcaacagat aaataatgtc
    95341 ggtgttcaac aaattgccgg agatctcaca gataactaca attcaggtaa taagatgttg
    95401 agtttgtctc aagcaactgc acagtctact tcagttgctg cgataggtgt agcagctcat
    95461 gaatgcggac atgcggtaca agatgcttcg ggttatgtcc cattgaagat tcgtgcagca
    95521 cttgttccag cagctaactt tggttcgatg atttcgttcc ccttgattat ggtaggtgta
    95581 ttgcttagct ggaactctac gttaatcaat atcgggattt tcgctttttc tttagcatta
    95641 cttttccaat tggtgacatt accagtcgaa tttaacgcgt ctcggcgagc aatccaaatt
    95701 ttgagtgaag gcggactact gacggaagaa gaagtaccga tggcaagaca cgtattattt
    95761 gcagcagcac tgacttatgt tgcagcagcg ctttcgacat tcctgcagct gttgcgcttg
    95821 atcttattgt tcggcggcaa ccgaagagat taaaataaag aagttgtgaa atcagcgctt
    95881 tgatctgagc taataccgag agttagctga ttgaatacca tttatttgga ataagaggat
    95941 gtgacaagaa ttttgtcaca tcctctttgt tttgttctca taaccttttt tcatatacag
    96001 ttcatgaacc gcttttatta acttgccaaa taacactgta ttgtgcgttg tatccagata
    96061 gaaagtctcc gtttcatctg aaattttctc atgctgatct gtaatgatca aatcagcatg
    96121 ttctgaatat gcggtaattt taacagcatc tttgcgaaat aactgctgca aatggctttg
    96181 aagatgataa tttcctgtaa actgtttggt tatctgcaaa tggatgagta actgctcttt
    96241 cgtttctgtt tgtagtaagt gttggatcaa ttgactaagg tattgactga tttggtttct
    96301 ttccccattt tttgaaaaaa ttgtatcgat tttttctctt aatttctttt cctgtataaa
    96361 agaactagaa tgattggacg tggcttctgg aaagcaaagt gtagaaaaac tactgctgga
    96421 ttcacccaac agttcgaaaa aaacaactgc caacacaaga aaataaaaat aaattggtat
    96481 tttattttct aaatggttga gaggaaactg ttgagttaag taagtcatca attgaccgac
    96541 ttgtcgacaa ataaggtttt tgcttgtgga aaataaaaaa ccaatctcct gtttttgtcg
    96601 aaaagagatt tgatttggaa aaaaacaata gaaaaaataa ttaaagtagg ctctctctgt
    96661 ttctgtctct tcacaagggc gactcactga aaaagaagta aagtattctg aataatcatg
    96721 tgtatgctgc aataagtcca tcaattcagt gatttcagaa gaagtttttg gaaaatatgc
    96781 ctgttgtttg tttcgtaata tgaataaagt taacagcaag tagatatttt tttcttgttt
    96841 tgaaattttt tctatttgct catctgtact gttcattttt agtgcattta attcaagtga
    96901 ggaaaatggc caatcgttac ctccaaatgt atctgaaaga aaaaagtaaa gatagagacg
    96961 gatagataac tcatttcctt caagagtaca gcaatttttt acagatagga tccgtaaatg
    97021 gaattttatt aaggaatgat tgagctgttt tgtcagtttt tcgagatagg agggcgatat
    97081 ataaagttgt tcaagtaaat atttttttgg tacagcagtt tgtggataat tgattagtaa
    97141 catcaaatag ttaaaacgat tggattcttt taggtagcat aattttaact tagaaaaaac
    97201 agctaacttt ttagtttgat cggtttcttt ggtttggatc tctcctttat gattagaata
    97261 aataaattca tcaatcaata aaaattgctt gagtgataca tttatttttc ggatcagttc
    97321 tttgattgtc cgttttggaa tatgtaagtc attggataat tcttgtaaag aacaattatt
    97381 tttttgaatg accatttgta gaacaagtaa ctcttttttt cttgcttcaa ttagcataaa
    97441 tacctccttt ttattctgtt tttgtatata gttagacaaa aactgtgagt ggaaagtcat
    97501 ttcagtctgt gttattctca cagagtgtcg ccttcttttt tatataacgt tatttaattt
    97561 ttttgttacc ttgtttattc tattgtttat ttcctagggt attttgtcaa gatattcttg
    97621 tttttaaggc ggaaaaattg atttttaatg gatataacta aatatgtttt gataattatc
    97681 aataatattt ttagaattat ttatgttatt tatttatggg tagatgaaaa gagacggagg
    97741 taagaatgat ggggagagta acaaattata gtaaagaata tttgctgttc aaaagtatgg
    97801 tatacgtgga agaatatgga atgaagtcaa ttactgcaag agagttagca gagttctgcg
    97861 gttgttctac atacccgatt tatacacatt tcaaatcaat cagcgggtta aaagagaaga
    97921 tattagaaga aatcactgtt tattttgaaa actacttagc tgaatgcagt tccgatgatg
    97981 ttttaagcat tgtctactta ttgaaagatt ttttttctat ccatgaaagt attcgtgaaa
    98041 tcattgcaaa atctgattta gacatggatt cgctatttaa gcggccattt ttctcatatg
    98101 tcaaaggtca cacgaagatc aaagaagaaa agtcgcttga attggtatgg cttaatgcat
    98161 tgggaagttt gcgctcagat gattcttctc aagattttct tgaaatgatg aacgctgttt
    98221 gggataaaaa cgaggtgacg gatgaatact tggaaaatat cttaaaggaa cagtcacctt
    98281 aggcagcaac atgaaaaagt agatcagcca cctttatttt tcgtaaaaaa gattgtaaaa
    98341 tgtctaacga aacattggaa tgaaggagga agcgacaacg ttaccacagc aatttatcaa
    98401 aaaatatcgt cttcttttag gcgaagaagc atccgatttt ttttctgcgc ttgaacaagg
    98461 aagcgtgaaa aaaggatttc ggtggaatcc actaaaaccg gcaggattgg acatggtcca
    98521 aacttaccat agcgaagaat tacaacccgc tccctacagc aatgagggat ttcttggcac
    98581 tgtcaatgga aagtctttcc tccatcaagc tgggtatgaa tatagccaag aaccaagtgc
    98641 aatgatcgtt ggaacagctg ctgcagcaaa acccggtgaa aaagttttgg atttgtgtgc
    98701 ggctcccggt ggtaaatcaa cccaattagc tgctcaaatg aaggggaaag ggttattagt
    98761 gacgaatgag atctttccga aacgtgcgaa gattttatca gaaaatatag aacgatgggg
    98821 agtttcgaac gcaatagtga caaatcatgc acccgcagaa cttgtccctc atttttcggg
    98881 cttttttgat cggatcgtgg ttgatgctcc ttgttcagga gaaggaatgt tccgaaaaga
    98941 tccaaatgca ataaaagagt ggacagaaga atctccgcta tactgtcaaa aacgtcagca
    99001 agagattttg tcttcagcaa taaaaatgct aaaaaataaa ggacaactga tttattcgac
    99061 ttgtacgttt gcaccagaag aaaatgaaga gatcattagc tggcttgtag aaaattatcc
    99121 agtaacgatt gaggagattc ctttgactca atccgttagt tcaggacgtt ctgaatgggg
    99181 aagcgtagct ggtttggaaa aaacaatacg tatatggcct cataaagatc agggtgaagg
    99241 acattttgtt gcaaagctga cttttcatgg acaaaatcag atgcataaag aaaagaagac
    99301 acgaaaaaaa agtaaagtgc aaatgacaaa agagcaggaa aaactctgga cggagttttc
    99361 aaatgatttt cattatgaag ctactggaag acttttagtg ttcaacgacc atctttggga
    99421 agttcctgag ttagcccctt ctctcgatgg tttaaaagtc gtacgtacag gtttgcattt
    99481 aggagatttc aaaaagaatc gatttgaacc tagctatgca ttagcgcttg ctacaaaaaa
    99541 gatagagaat ataccttgct tgccgatcac tcaaaaggaa tggcaatctt acacagcagg
    99601 agaaacattt caacgtgatg ggaatcaagg atgggttttg ctagtattag ataagatacc
    99661 tgtcggattt gggaaacaag taaaaggaac agtaaagaac tttttcccta aaggattgag
    99721 atttcactga gtggattagt tcgtttattt ttttgtctat gctatgatgg agatagataa
    99781 aaaggagctg atacttatga aaacatcaac aaaagtaaca atcggattaa gcgtagcagc
    99841 cgctgccagt gtagcgacag cagtcgttgt atcgggaaaa gtaatggaaa agatccatca
    99901 tatgactact cggacgaaag taaaaaaatt cgtctatgac aaatttgatg gaaatgaaaa
    99961 attactagaa atcgtagatg gtctttcaga tagtgacttg gattctttga tgggaatgtt
   100021 agcaaaaatc aaatcaggaa aaaagaaaat ctctgtttat ggtgattcaa tcaaagattc
   100081 aaccgaagat gtaaaagacc ggctaatgca ttttgttgaa aaaatgatgt aagagaaact
   100141 agcttttgaa cactattcat tcgaaataag gggttgtgac aaaattattg tcacaacccc
   100201 tttaatctat ctttaattat gttcatgaag caataaaaga tagcaaaaca gtaaatcgtt
   100261 ggcttttttt agattgaaac cagactgttc ttgaaatttt tcgattcgat attttagagt
   100321 attacgatga agaaacagtg tttttgcagc agagctgaca ttgcctaatt cattccataa
   100381 ttcttgaatg atcacttcca tttcattttg tttgatcagt tctatgtaac ttttgatcaa
   100441 cttactatct tttacagtat cttttgtata gtaatgtaaa gccacatctt gcatagaaaa
   100501 agtacggctg tgagtataaa gattgttttg ctctgttaaa aaaatttttc tttcttcagc
   100561 aaacaaaggg acgaggtcgg tgccaggtga atggaaagaa ccaacgaata cagacgttgt
   100621 cgtatcaaaa tcagcatcta aagatagaaa aataccgttg atttcagtag catcaagata
   100681 atcacggttt atttgttcga ctaagagcgc atctgtgtct gtataaaaaa agaaatcagc
   100741 agaatagcga aataattcca aaatagtatc ttgccattct ttttttaaga attctccttt
   100801 tgattcgacg tgaagctgga tcaaacgaaa gcttttttct tgaacacaag aagcatcttt
   100861 aaaaagatag tgataccatg ggtgtttttt ttgatcgttg attacaggga ataacgcttt
   100921 caaaaggctg gtttcttgtt gagataatga atcttgtttg atccagataa aagcatcatc
   100981 aattgcaaaa gaaaggatat ccgcttctga tgctggagag ttttttttct gtgcttgtgg
   101041 gtaaagagca agtaatttat ccattttcat cttgttcacc tcttgtattt attttaccat
   101101 agaaaaaaaa gttagttaca gcctttttat catatgctaa agtaaaacaa gaaaaaacaa
   101161 aggcagggaa gggtaattgg taaatacaaa tcttgatgca gtagaaaaag aaaaatggat
   101221 gcgccttgca ttggcagaag caaagaaagc agaaatgctt catgaagttc cgattggagc
   101281 agtggttgta ttggatggaa aagtgattgg aagaggatat aaccttagag aaaccacgca
   101341 agatgctact acacatgcag aaatgcttgc aatcaaggaa gcctgtgaaa aagtgggaag
   101401 ctggcgcttg gaagatgctg cactttttgt taccttagag ccttgtccta tgtgcagcgg
   101461 cgcgatgatt ttgtctcgtg tagcagaagt ttatttcggc gcgtatgatc caaaaggcgg
   101521 aacagccggt accttgatga atcttttgga ggacgagcgg tttaaccacc aagcatatgt
   101581 agaaggtggc attttagaag acgaatgtgg gatgattttg actgactttt tccgaaagct
   101641 ccgccagcga aaaaagaaat taaaaaaaga ctggtcaacg aatgaaaaat aaggtatact
   101701 attctttgcc gaaaggctag gacaatggtg ggcttgtgaa gcgtgtcagg tctggaagga
   101761 agcagcacta agcaggttcc gccatgtgtc tgattataat gaaacgacaa cagactttcg
   101821 ggtctgtttt ttttattttt atagtactgt aaaaatgaat gttcctgatt ttttagccag
   101881 actgatttat cgaatattgt acttatacaa tttgcttcaa ggcaggaaaa actctgaaat
   101941 agagcttgtt tcaatggaag aaaaagctgc ctatggtatg ataaagataa agagaggcga
   102001 gagggtacat ggaaaaaata gtgattttac atacgaatga tctgcattct catttagaaa
   102061 attggccaag gatcagaagg tttttggatc aacgtaaacg agaaaacgaa aagaaagaaa
   102121 aaacgacaac gattgcagta gatctaggtg attttgtgga tcgttggcat ccattgtcag
   102181 aagcaacgaa tggacaggaa aatatcttgc tgatgaatga agttggttat gatgcagcga
   102241 cgataggaaa caatgaaggc gtaggaaatt ccaaagaaga gttgaatcat ttatacgatc
   102301 atgctgagtt tgatatcatc ctggataact tattcgataa aaatacgctc cagccaccgg
   102361 catggacgaa accatataaa atcattacaa cgaaacacca gacgaaaatc ggactaattg
   102421 catttactgc tccatttccg cttacttata atccgaatgg ctgggacata cggaatcctt
   102481 atgatatttt gccagaatta gtcgaagatt tacgttcaca agtggatgtt ttagttttga
   102541 tgagtcatct cgggattcag gatgatttcc aaattgcaaa agaaatacca gcaattgatg
   102601 ttattttagg atcgcacacc catcatttat tcagagaagg tcacgtaatc aatgatgtcc
   102661 aaatagcagc cgctggaaag tacgggcagt atgtcggtga agtccattta accatcgatg
   102721 aagagaaaaa aatccttaag cattcagcca aagccatccc taccgaaaca atgacagctt
   102781 ttacagaaga tgaacaagaa ataaatagtt atctagaacg tgggcatgaa ttattaaaag
   102841 aaaaagaagt agcagatttg ccattttctc tgagtctaga tatcttcaat gagcattcgt
   102901 ttatccaagt agcctttgag gcggtgaaag aacgaggaaa gacggaagca gcaatattaa
   102961 acagtggtct gtttttaact gaaattccaa aagggcgggt caatcaggat cagcttcaca
   103021 ctgcgttgcc gcatccgatg cacttgttaa atgtcacatt gggtggaaat gatctgatcc
   103081 gcttagtttt agaaatagaa aaaaatcgta actttttacg taactatcct atgaagggaa
   103141 tgggatttcg cggtaagatt tttgggcaga tggtctataa tggaatcaca tatgattcta
   103201 ttaaccatca agtcttttgg aagaacaagc caatcgatct gaataaaaat tatactttta
   103261 ctaccgtaga tcatttgatg tttgttccat tttttccaac gattgagatt gctggaaaaa
   103321 atgaattttt gttccctgaa tttatccgaa gtgtggtagg agattacttg aaagctcact
   103381 acccaatcaa ataaaaacaa ggtataataa aaaagatagg tggtgaacgc atgtctgcaa
   103441 aacaaaatga acagcagaac gttgagcata aaacagaaat tgctaagaaa aaatcatcag
   103501 ctgaacagga aacaacagtc accgaagaac tgacagctgc tttggaagaa atcgttgagg
   103561 agcctaaagc agaaaaagtc aaaggcgagc tagtgacact gttagatgac agtaattttt
   103621 tgataggtga aagacattat cggcttgtgt ccgattatcg tgaaggattt aatgcagaaa
   103681 agcttggaga acgttacagt gatgtactag cccgatatga ttatatcgta ggagattggg
   103741 gttatgaaca actacgccta aaaggatttt tccaagcgga taatcgacgg gcgcatccag
   103801 atcagcgaat cgattccttg gaagactatc tttacgaata ttgcaatttt ggttgtgcgt
   103861 attttgtcat cgagagaatc ggcggtaaaa aagaaaagac aactcagcgc cgaaaaaaga
   103921 aaaaaaacca taatcgtgcg tatatcgatg agaaaaaagg accagtcgca tctaatcgca
   103981 aaaaaccggt tattaaaaat cgaaaaacag agtcagcaaa aacctctgaa aaagtaaaaa
   104041 aacaagaaca acctaaacaa gtagaaaaaa caaaaacagc atttacgatc agaaaaaggg
   104101 aagagtagtg gatgaatgga ctataaagga tatttaattg atttagacgg aacgatttat
   104161 cgtgggacac aacccatacc ggccggtaaa cgatttgtgg aagaattgca aaaaagaaaa
   104221 ttacctttct tgtttgttac caataacacg actaagtcac cagaaacagt agctaatcgt
   104281 ctagcagatg agtttgacat tcatgtagct ccagagacag tctacacagc tactttggca
   104341 acaatcgatt ttatgaaagc agatggaaaa gggaaaaaag tctatgttat cggagaagca
   104401 ggattgattg acttgatttt agctgccgga tttacatggg aagaagaggc tcctgactat
   104461 gtagtggtag gcttagataa ttatctgacc tatgaaaaag tagttaaagc aacacttgct
   104521 attcaaaaag gtgctacttt cattggaacg aacccagata agaatatacc tactgaacgc
   104581 ggccttcttc ctggagcagg gtcagtcatc tcttttgtag agacagcaac ccaaacgccg
   104641 ccgatctaca tcggaaaacc agaagccatc attatggata aagccgttga agtattaggg
   104701 ctgcaaaaag aagaagtaat catggttgga gataactatg aaacagatat ccaagctggg
   104761 atacgcaata atatagatac tttgctcgtt ttatcaggtt ttacaaaaga agaagatgta
   104821 cctgggttgc ctatcccagc tacctatgtg aaacaatcac tggatgaatg gagcttctaa
   104881 tatgaaaaat tcgagatggc agtggatgga atatgctgga ttgttcagcc tatttctgac
   104941 actgatcagt ctggcagttg gtgtgacgat caactttcga ccactatacg tatttgatat
   105001 cggacatttg caaattttgg attatacttc tttagatcaa gagacgttac tgaaaaattt
   105061 tgatcaccta atgaattatc tcaataatcc cttcaaaacc atcctcagct tgccagattt
   105121 cccagtttct gctagcggag cccatcactt ttatgaagtg aaaattttgt ttttagtgga
   105181 ttatgctgtg tttttcatca ctttgatccc gagtattttg tttatcaaat atttgcaaaa
   105241 gaatgatcgg ctttggcggt tgattcgtcc gtttcaaatc ggcatgttac tgccagttgt
   105301 tttcggtttt ttcatgatga taggatttga tcgctttttt atcctttttc atgaaacgtt
   105361 tttcaacaac gatgactggt tattcgatcc cgttactgat ccaatcatca atgtacttcc
   105421 agaagaattt ttcatgcata gctttatctt attttttgta ttattagaat tattttttgc
   105481 tgtttttctt ttcttaggaa aaaatagctt gaaacaaaca aaaaagaaag aactcgtcta
   105541 aatagacgtt ttctttcttt ttttgttgaa ttattgagta aggcgacttc ttttttctgg
   105601 ttctttgtgt gctaatcgac tggcagcagc agcggcgatc gctccgacga tatcatctaa
   105661 gaaggtatgg acatgaacgc catcgtggct gtttagttct tttaaaatac caggtttcac
   105721 cttgtcgata taaccataat tcgtaaagcc gatcgtaccg taaacattca cgattgacaa
   105781 ggctaggatc tcatcgatac cgtaaaggcc ttcgtcatct tcgataatat gttgcaacgg
   105841 actcatcaat tttttctttt ctgctaatat atctaattgg attccagtga taatggcgtt
   105901 atgtacttca cgctttgtta gcacgctgtt gacactttca gtacaatccg ccaaagtcaa
   105961 atcagaaata tagtcttttt gtaaaaacat gacaagttgt gcgatatctt ctacagttac
   106021 gccacgttcc ttcaatagtt ctcttgcctt ttcttctaaa gtctcagttt tgacgaccat
   106081 attattgctc cccctttatt ttttctttct ctatttcatg ttaacggaac atgaaaaaaa
   106141 tgcaagaaac tgctttcggg tttaacttga aatgcaaaga gatataaaaa atcaactagg
   106201 acgaagattt ttatcgtata agcttgtgct gtgaccaggc tgagttcgtt cctttggatt
   106261 aatatagtgt aaagcgttgt tcactgcagt aggtgcttca ccgagcccag tagcaatcag
   106321 tttcactttt ccttcatagg tacagatgtc accagctgca taaacgcctg gaatagaagt
   106381 agacatatct gattttacag taatggcatt tctggtacta tcaagtcccc aagaagaaag
   106441 atgttctaaa ttagaagaga atccataatt gacgatcaga gaatcaatca tcaaatcaat
   106501 cgtctcgtca cttttcactt tttttaaccg gatatctgtc agttccccat tattgcctga
   106561 taatccatcg atgagatagg gagtaagcaa gttgacagat gaagatttca agcgtgatac
   106621 actatgttcg tgcgcacgaa attccgggcg acgatgaatc aagtaaactt cgcttgcaat
   106681 aggctctaac atcaacgtcc aatcgatagc agaatcacca cctccagcaa tagcgacttt
   106741 ttttccagca tacttcatca aatcattcac gaaataatcc aatccgtggt tttcaaatga
   106801 ttcagcatta tctaaattca attttcttgg ctggaatgaa ccatttccta aagctaaaat
   106861 gactgctttg gaataatgga tgcctttatt tgtagtaatc tcgataactt cgtcttcacg
   106921 agtaagcgag agaacttctt cttttaaatg gaatgtatgg ttaaaagtag ttaattgttt
   106981 ttctaattga tcgattaatt cacttgcttt tattgctgga tacccaggaa tatcgtaaat
   107041 atatttttcg ggatacaaag ttgctaattg accaccaagt tgaggtagac tgtcaatgat
   107101 ttttgtttta gcttggcgca ttcctgcgta aaaagcggca aacatcccta caggacctgc
   107161 accgatgatt gtaatgtcat agatttccat aaaaattcct cccttttcac actatatcag
   107221 aatttaattg agaatgcttc tcaaaaatgt ttgaattcga aatcgaaacg gtaagttata
   107281 gaatgtatct agtgatgaaa aataaaagaa aacaaatcta gtatttttac gagaggttag
   107341 gtattatgtt attattatta tgaagtatgc aaat
//
LOCUS       DAFENC010000005       100707 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.005, whole genome shotgun sequence.
ACCESSION   DAFENC010000005
VERSION     DAFENC010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 100707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 100707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..100707
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.005"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(552..2165)
                     /locus_tag="LP493_000455"
     CDS             complement(552..2165)
                     /locus_tag="LP493_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL2132630.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(2306..3214)
                     /locus_tag="LP493_000456"
     CDS             complement(2306..3214)
                     /locus_tag="LP493_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2132631.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            3397..4521
                     /locus_tag="LP493_000457"
     CDS             3397..4521
                     /locus_tag="LP493_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBL2132632.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            4748..5665
                     /locus_tag="LP493_000458"
     CDS             4748..5665
                     /locus_tag="LP493_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2132633.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            5658..6491
                     /locus_tag="LP493_000459"
     CDS             5658..6491
                     /locus_tag="LP493_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL2132634.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            6574..7692
                     /locus_tag="LP493_000460"
     CDS             6574..7692
                     /locus_tag="LP493_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBL2132635.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            7686..9584
                     /locus_tag="LP493_000461"
     CDS             7686..9584
                     /locus_tag="LP493_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HBL2132636.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            9578..10801
                     /locus_tag="LP493_000462"
     CDS             9578..10801
                     /locus_tag="LP493_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBL2132637.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(10887..12821)
                     /locus_tag="LP493_000463"
     CDS             complement(10887..12821)
                     /locus_tag="LP493_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBL2132638.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            13047..13703
                     /locus_tag="LP493_000464"
     CDS             13047..13703
                     /locus_tag="LP493_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBL2132639.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            complement(13777..14130)
                     /locus_tag="LP493_000465"
     CDS             complement(13777..14130)
                     /locus_tag="LP493_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBL2132640.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            14322..15251
                     /locus_tag="LP493_000466"
     CDS             14322..15251
                     /locus_tag="LP493_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBL2132641.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            15262..16098
                     /locus_tag="LP493_000467"
     CDS             15262..16098
                     /locus_tag="LP493_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HBL2132642.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            16346..17122
                     /locus_tag="LP493_000468"
     CDS             16346..17122
                     /locus_tag="LP493_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2132643.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            17298..18041
                     /locus_tag="LP493_000469"
     CDS             17298..18041
                     /locus_tag="LP493_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2132644.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            18034..19614
                     /locus_tag="LP493_000470"
     CDS             18034..19614
                     /locus_tag="LP493_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HBL2132645.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(19865..20344)
                     /locus_tag="LP493_000471"
     CDS             complement(19865..20344)
                     /locus_tag="LP493_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBL2132646.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(20360..21112)
                     /locus_tag="LP493_000472"
     CDS             complement(20360..21112)
                     /locus_tag="LP493_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBL2132647.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            21229..21299
                     /locus_tag="LP493_000473"
     tRNA            21229..21299
                     /locus_tag="LP493_000473"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21261..21263,aa:Gly,seq:ccc)
     gene            21660..22385
                     /locus_tag="LP493_000474"
     CDS             21660..22385
                     /locus_tag="LP493_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HBL2132648.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            22640..22906
                     /locus_tag="LP493_000475"
     CDS             22640..22906
                     /locus_tag="LP493_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HBL2132649.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPSYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            22903..23334
                     /gene="ruvX"
                     /locus_tag="LP493_000476"
     CDS             22903..23334
                     /gene="ruvX"
                     /locus_tag="LP493_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HBL2132650.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            23359..23664
                     /locus_tag="LP493_000477"
     CDS             23359..23664
                     /locus_tag="LP493_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HBL2132651.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(23745..24890)
                     /locus_tag="LP493_000478"
     CDS             complement(23745..24890)
                     /locus_tag="LP493_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL2132652.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(24951..25598)
                     /locus_tag="LP493_000479"
     CDS             complement(24951..25598)
                     /locus_tag="LP493_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2132653.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            25792..26085
                     /locus_tag="LP493_000480"
     CDS             25792..26085
                     /locus_tag="LP493_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132654.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            26129..26440
                     /locus_tag="LP493_000481"
     CDS             26129..26440
                     /locus_tag="LP493_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132655.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            26437..27061
                     /locus_tag="LP493_000482"
                     /pseudo
     CDS             26437..27061
                     /locus_tag="LP493_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            27202..27360
                     /locus_tag="LP493_000483"
     CDS             27202..27360
                     /locus_tag="LP493_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132656.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            27361..27723
                     /locus_tag="LP493_000484"
     CDS             27361..27723
                     /locus_tag="LP493_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132657.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            27760..28608
                     /locus_tag="LP493_000485"
     CDS             27760..28608
                     /locus_tag="LP493_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HBL2132658.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            28598..30073
                     /locus_tag="LP493_000486"
     CDS             28598..30073
                     /locus_tag="LP493_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HBL2132659.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            30339..30746
                     /locus_tag="LP493_000487"
     CDS             30339..30746
                     /locus_tag="LP493_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HBL2132660.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            30749..30964
                     /locus_tag="LP493_000488"
     CDS             30749..30964
                     /locus_tag="LP493_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132661.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            30968..31348
                     /locus_tag="LP493_000489"
     CDS             30968..31348
                     /locus_tag="LP493_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBL2132662.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            31482..31637
                     /locus_tag="LP493_000490"
     CDS             31482..31637
                     /locus_tag="LP493_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HBL2132663.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            31706..32179
                     /locus_tag="LP493_000491"
     CDS             31706..32179
                     /locus_tag="LP493_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HBL2132664.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            32176..33870
                     /locus_tag="LP493_000492"
     CDS             32176..33870
                     /locus_tag="LP493_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBL2132665.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            33836..34021
                     /locus_tag="LP493_000493"
     CDS             33836..34021
                     /locus_tag="LP493_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132666.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            34025..35200
                     /locus_tag="LP493_000494"
     CDS             34025..35200
                     /locus_tag="LP493_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBL2132667.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            35193..36716
                     /locus_tag="LP493_000495"
     CDS             35193..36716
                     /locus_tag="LP493_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBL2132668.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            36772..37056
                     /locus_tag="LP493_000496"
     CDS             36772..37056
                     /locus_tag="LP493_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBL2132669.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            37043..37378
                     /locus_tag="LP493_000497"
     CDS             37043..37378
                     /locus_tag="LP493_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBL2132670.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            37673..38299
                     /locus_tag="LP493_000498"
     CDS             37673..38299
                     /locus_tag="LP493_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132671.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            39041..39877
                     /locus_tag="LP493_000499"
     CDS             39041..39877
                     /locus_tag="LP493_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBL2132672.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLVNCYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            39941..40372
                     /locus_tag="LP493_000500"
     CDS             39941..40372
                     /locus_tag="LP493_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2132673.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(40434..41756)
                     /locus_tag="LP493_000501"
     CDS             complement(40434..41756)
                     /locus_tag="LP493_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HBL2132674.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(41910..43550)
                     /locus_tag="LP493_000502"
     CDS             complement(41910..43550)
                     /locus_tag="LP493_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HBL2132675.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            43883..44353
                     /locus_tag="LP493_000503"
     CDS             43883..44353
                     /locus_tag="LP493_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HBL2132676.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            44575..45678
                     /locus_tag="LP493_000504"
     CDS             44575..45678
                     /locus_tag="LP493_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBL2132677.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLKDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            45962..46642
                     /locus_tag="LP493_000505"
     CDS             45962..46642
                     /locus_tag="LP493_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBL2132678.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            46732..47766
                     /locus_tag="LP493_000506"
     CDS             46732..47766
                     /locus_tag="LP493_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBL2132679.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            47780..48115
                     /locus_tag="LP493_000507"
     CDS             47780..48115
                     /locus_tag="LP493_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132680.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            48099..50579
                     /locus_tag="LP493_000508"
     CDS             48099..50579
                     /locus_tag="LP493_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132681.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWKLTAGPTS"
     gene            50635..52194
                     /locus_tag="LP493_000509"
     CDS             50635..52194
                     /locus_tag="LP493_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2132682.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            52191..53555
                     /locus_tag="LP493_000510"
     CDS             52191..53555
                     /locus_tag="LP493_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBL2132683.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            53726..54796
                     /locus_tag="LP493_000511"
     CDS             53726..54796
                     /locus_tag="LP493_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2132684.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            54811..55479
                     /locus_tag="LP493_000512"
     CDS             54811..55479
                     /locus_tag="LP493_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2132685.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            55499..56077
                     /locus_tag="LP493_000513"
     CDS             55499..56077
                     /locus_tag="LP493_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL2132686.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            56478..57389
                     /locus_tag="LP493_000514"
     CDS             56478..57389
                     /locus_tag="LP493_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBL2132687.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(57477..58394)
                     /locus_tag="LP493_000515"
     CDS             complement(57477..58394)
                     /locus_tag="LP493_000515"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HBL2132688.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            58596..59033
                     /gene="zapA"
                     /locus_tag="LP493_000516"
     CDS             58596..59033
                     /gene="zapA"
                     /locus_tag="LP493_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBL2132689.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            59092..59640
                     /locus_tag="LP493_000517"
     CDS             59092..59640
                     /locus_tag="LP493_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HBL2132690.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            59755..62115
                     /locus_tag="LP493_000518"
     CDS             59755..62115
                     /locus_tag="LP493_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBL2132691.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEEQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLYDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            62202..62516
                     /gene="trxA"
                     /locus_tag="LP493_000519"
     CDS             62202..62516
                     /gene="trxA"
                     /locus_tag="LP493_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBL2132692.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            62698..64476
                     /gene="uvrC"
                     /locus_tag="LP493_000520"
     CDS             62698..64476
                     /gene="uvrC"
                     /locus_tag="LP493_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HBL2132693.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            64621..65520
                     /locus_tag="LP493_000521"
     CDS             64621..65520
                     /locus_tag="LP493_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2132694.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            65513..66775
                     /locus_tag="LP493_000522"
     CDS             65513..66775
                     /locus_tag="LP493_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2132695.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            66936..68834
                     /locus_tag="LP493_000523"
     CDS             66936..68834
                     /locus_tag="LP493_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HBL2132696.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(69164..69883)
                     /locus_tag="LP493_000524"
     CDS             complement(69164..69883)
                     /locus_tag="LP493_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBL2132697.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     gene            70220..70552
                     /locus_tag="LP493_000525"
     CDS             70220..70552
                     /locus_tag="LP493_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132698.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            70539..72542
                     /locus_tag="LP493_000526"
     CDS             70539..72542
                     /locus_tag="LP493_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HBL2132699.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            72561..73031
                     /locus_tag="LP493_000527"
     CDS             72561..73031
                     /locus_tag="LP493_000527"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HBL2132700.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            73052..73636
                     /locus_tag="LP493_000528"
     CDS             73052..73636
                     /locus_tag="LP493_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HBL2132701.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            73651..74637
                     /locus_tag="LP493_000529"
     CDS             73651..74637
                     /locus_tag="LP493_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HBL2132702.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            74627..74938
                     /locus_tag="LP493_000530"
     CDS             74627..74938
                     /locus_tag="LP493_000530"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HBL2132703.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            74960..76741
                     /locus_tag="LP493_000531"
     CDS             74960..76741
                     /locus_tag="LP493_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HBL2132704.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            76734..78110
                     /locus_tag="LP493_000532"
     CDS             76734..78110
                     /locus_tag="LP493_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HBL2132705.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            78117..78752
                     /locus_tag="LP493_000533"
     CDS             78117..78752
                     /locus_tag="LP493_000533"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HBL2132706.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            78782..80137
                     /locus_tag="LP493_000534"
     CDS             78782..80137
                     /locus_tag="LP493_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HBL2132707.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(80329..81723)
                     /locus_tag="LP493_000535"
     CDS             complement(80329..81723)
                     /locus_tag="LP493_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBL2132708.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRTQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            81815..82786
                     /locus_tag="LP493_000536"
     CDS             81815..82786
                     /locus_tag="LP493_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HBL2132709.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            82783..83565
                     /locus_tag="LP493_000537"
     CDS             82783..83565
                     /locus_tag="LP493_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBL2132710.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(83734..84105)
                     /locus_tag="LP493_000538"
     CDS             complement(83734..84105)
                     /locus_tag="LP493_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL2132711.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            84239..84682
                     /locus_tag="LP493_000539"
     CDS             84239..84682
                     /locus_tag="LP493_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HBL2132712.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(84725..85534)
                     /gene="yidA"
                     /locus_tag="LP493_000540"
     CDS             complement(84725..85534)
                     /gene="yidA"
                     /locus_tag="LP493_000540"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HBL2132713.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(85553..86920)
                     /locus_tag="LP493_000541"
     CDS             complement(85553..86920)
                     /locus_tag="LP493_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBL2132714.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(86904..87734)
                     /locus_tag="LP493_000542"
     CDS             complement(86904..87734)
                     /locus_tag="LP493_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HBL2132715.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            87897..88334
                     /locus_tag="LP493_000543"
     CDS             87897..88334
                     /locus_tag="LP493_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HBL2132716.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            88410..89030
                     /locus_tag="LP493_000544"
     CDS             88410..89030
                     /locus_tag="LP493_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HBL2132717.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            89219..89725
                     /locus_tag="LP493_000545"
     CDS             89219..89725
                     /locus_tag="LP493_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HBL2132718.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            89742..90641
                     /locus_tag="LP493_000546"
     CDS             89742..90641
                     /locus_tag="LP493_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBL2132719.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            90728..91612
                     /locus_tag="LP493_000547"
     CDS             90728..91612
                     /locus_tag="LP493_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBL2132720.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(91804..91875)
                     /locus_tag="LP493_000548"
     tRNA            complement(91804..91875)
                     /locus_tag="LP493_000548"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(91840..91842),aa:Arg,seq:ccg)
     gene            91935..93269
                     /gene="rpoN"
                     /locus_tag="LP493_000549"
     CDS             91935..93269
                     /gene="rpoN"
                     /locus_tag="LP493_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HBL2132721.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            93418..94509
                     /locus_tag="LP493_000550"
     CDS             93418..94509
                     /locus_tag="LP493_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HBL2132722.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            94550..95551
                     /gene="gap"
                     /locus_tag="LP493_000551"
     CDS             94550..95551
                     /gene="gap"
                     /locus_tag="LP493_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBL2132723.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            95661..96851
                     /locus_tag="LP493_000552"
     CDS             95661..96851
                     /locus_tag="LP493_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HBL2132724.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            96955..97710
                     /locus_tag="LP493_000553"
     CDS             96955..97710
                     /locus_tag="LP493_000553"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBL2132725.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            97826..99124
                     /gene="eno"
                     /locus_tag="LP493_000554"
     CDS             97826..99124
                     /gene="eno"
                     /locus_tag="LP493_000554"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HBL2132726.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            99523..100662
                     /locus_tag="LP493_000555"
     CDS             99523..100662
                     /locus_tag="LP493_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HBL2132727.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT        33405 a        17204 c        20782 g        29316 t
ORIGIN      
        1 ttaaataaat aggaacaaaa aaattaaatt atttaataca cacattaggg atcattcatt
       61 gaaggattag aagacaacga ggatggcgaa aaatatgatt acaatagaaa agtcgttcta
      121 aaccaatcag ttcctagtat cacacaacgc aagccagtcg atttggtgag attagaggag
      181 tgaaagcaaa ctttattata taagaaaaaa tattcgaaag ggatgctagt ttaggtacta
      241 gtgctgatag attaatatga tgcctcgtaa tattaggcgt agttactcta gagacatcac
      301 tatggactat gatttgtctc agagtcacaa catgtttttt tatgaaaaga aacagctaaa
      361 ataattaaat tgcgcaatgt ttaaactttc ttaaactata acctaataaa tgtgaagaaa
      421 taatgcacaa tttcttcaca tttatcttct attctatata cataccaacc aacaacccta
      481 tatacttttt catttttact cctcaagtaa aaataactcc tagaccgcgg ctacccaccg
      541 cggtcgtttt tttattcttc aatcaaaatc gctttgatac ccaaacctgc caagattcgg
      601 gcagaagtat aagtattcaa tcctcttctg aaagtaatgt aaactttttt atcttttggg
      661 atttcattga ttcgatctcg taactcattc attggaatat tttttgttgc cgagatactg
      721 ccagaaggtg ctttattagg ttcacgtata tctaaaaaga acgcttcttt caaatcgttt
      781 tcgggtatat cacttgcttt gatcgtttct acgatattcg tcatttgatt gattgcgaca
      841 taaccagcta tattcaacgg gtcacgggta gtagaatacg gtggagagta aggcaactcc
      901 aaatcaggca aatcaaagac tgtcaagttt ccggtgattg ctacagaaag ttctcccatc
      961 cgtttatcga cacctttttc tccaaatgct tgtccaccta aaatacgacc gctatctgca
     1021 tcaaaaatca gctttagatt taatcttgta gcttctggat agaaataggc atggtcaaag
     1081 ggagtgataa aaacagtttt ataatttgtt atgcctgatg cttttaattc atgttctgtc
     1141 attcccgcat aacttgctgt atgatcaaag atttttgcga cacctgcacc aatatatccg
     1201 cgatagcgca taggcgtacc atttaaaata tctgccagca tatgtccttg acgattggcc
     1261 gcactggaaa gcatactttg gatcggctga ccagtcacta cactagtcgt ttcgataata
     1321 tcgccaatcg catagatgtc cggcagattg gtttgtaact ggtcatcaac aatgatctga
     1381 cctgtatctg ataattgtat gccggttgct ttcaccactt cattcttcgg agaaacacca
     1441 acagcaaaaa ttagcatatc agcagaaagg acggagccat ctgataatac tatttctcga
     1501 cctttatcac ggatctcagt aactcttgtt tctaaatgaa cggctaatcc ttctttcagc
     1561 aatttgtcat aaactaaatt agcaatttct ggatcataag ggaaagcgac ttgtggcaat
     1621 tgatcgatta aagtcacgtc taagccgcga tgcttgaaat tctcagctaa ttccagaccc
     1681 ataacacctg caccaagaat gacgacatgt tgtggatttt tttcttcaag gaacgatttg
     1741 attcgatccg catccgtcac actacggagg acaaagccgt tttctgcttc aaaaactccg
     1801 ggaatatccg gataatctgg tctagcacca gaagagatga tcaacttatc gtaatctgtt
     1861 tttatttctt catttgtgga taggtcttta actgttaatc gcttagtaga aggatcgatt
     1921 gctgttactt cgtgtttagt aaagacatcg atgttgtttt ttgttttcaa tatttctggt
     1981 gtacgttcga tcagcgagtc acggtcagtg atcacacctc ctaaataata aggcaaagca
     2041 caacttgcat aagaaatatt ttctccgcgt tcatagataa tgatttcgtg cgcttcattc
     2101 aatcgacgga aacgagtggc aaatgaagga ccgccagcta caccgccaat gacaacaact
     2161 ttcataaaaa catctccttt tctacgttga tcgtactatg ttatggtaaa aaacagcaaa
     2221 taattgtgcc ggaaaattat tgtttatttt gaatagacag aaaatataga gaaataattt
     2281 gtggataaaa cctaaaaatt tttttctatt ttaaggatag ataatacttt gaaggggata
     2341 accctgtata ttttttaaaa gctgaagaaa aatgatggat cgaatgaaat cctaatatat
     2401 ctgcaatttc tgtataggtt aattcatttt ctagcacgag acgttttgct ttttccattt
     2461 ttagttcttt aaaatagcta ataacacttt ttccattcac ttttctaaaa tgttttttta
     2521 agctggctgg actgataaaa aaaatttggg ctaattgttc aagcaaaaaa ttttctgaaa
     2581 gatgttcttc taaatatcgt atgattggat caactaattc atctgaataa agaatatgct
     2641 tttttttagg aatgactttc tcatttgaag gtattgtcaa taaagcaagt tcctgttgat
     2701 aatgccttgg taaggaagac aattgaattt tttgcagaca ataagtaact aataaggaaa
     2761 gcaaatgaat gctcatctgt tggcatagta tgaaaaaaga attgatttcc tgatcatagg
     2821 aaatagctgg cttactatgt tttagataat caattttgaa ctgttcattt ttcagaaaag
     2881 taatgataga tgttatttct tgatctatag aaaaagattg tcccgtaata tgtgctaata
     2941 attgctcatc aaaataaaac tggataatga taaaagtttg tgtttccttt tgagtagaaa
     3001 agatttggac ttcttgctgt ttatcaatga ataaaaggga aggattatct agttctatag
     3061 atttatgtgc aaattcagca tataaattag cgctttcatt tattagtagt cgaaaatagg
     3121 gagcagcaga taaatgaaga tgggtatcta tggaataggt tagtgttttt ttgacaagat
     3181 tggaggattg gttgtttgtt aacaaaagaa ccactttcct ttctcttttt atataaaaag
     3241 ctttctattt ataattaatg actattataa caaaaatgaa aagccaaaac gacaagtaaa
     3301 atattttttt atataaatat ttgtgttact aattccgtta atatacataa gtgaaagcgt
     3361 tttatataag aacttgaaaa gaaagaaggg atagacatga aaaaaagata caaattggtg
     3421 atagctttgc taaacattac cctattattc agcttaagtg catgtggaaa aactaacgaa
     3481 gaagtaacag caaacatcgc agatccaatg ataaaaaaag ccactacatt agaagtatat
     3541 gtcgcaaacg gcaaactgac aaactatgtt gaaaatgctg caaaaatcta taaccgcaaa
     3601 actggagcaa atattgactt aaaaattgtg aatgtagctt cgggaacagc aacagtacaa
     3661 atgatcaccc caaaattggt aacacacgaa gatatgccgg atattatctc catggcagac
     3721 acttcagcag caggtgtgct ggaaaaattt caagatgctt tttatagtgc tgatgaatat
     3781 ggattttatg acaaatatgg cgatcagttt tatgatcaaa aattgaatat tttgcgtcaa
     3841 caaacgagta atgaaacgat tattccttgg gctagtgatt ttaccccagc actttgttat
     3901 tatcaaccaa aaaaatttgc tgaaataggt gtagattttg aagaaatcag ttcttgggaa
     3961 gaatatatcc aggtggcaaa agcattaaaa gaaaaaactg gtagttttgg aattgccttg
     4021 ccagaatctg gggaccaaga attgtttatc aacatgctag cccagcagaa tcaatctttg
     4081 cttgatgaag aaggaaatat ccgtctgaat actaaagaag cgaaacatgc tgcaaagtta
     4141 atcaaagaaa tgatcgactc agatattgta catttctacg gtgcacaaga tgctgagaaa
     4201 gcatttcaag aatctgcaat gtttgttgct ggcggctggt atgctacgaa tatgtctttg
     4261 aattttcctg atgcatctga caaatggcgc atggctccac tgattccttt ttcaaaagaa
     4321 aatccaggaa aaggtgcagt atcaggagga tcaagttttt atgtccctaa agatgcaaaa
     4381 aatccacaag tggcacaaca atttcttaca tttatgctga cagatgaaga atgcttagcc
     4441 aacgcactgg agctgggcgt ggctacatct aactcattgg cctatcaaac agaagcagct
     4501 gagaaaaagt ttgactacta aggaggacaa aaatactatg aactattgaa taaaatcaat
     4561 gaaaatacat caaatactgt tttaccagcc acttattcag atgctacgtc ttatttgact
     4621 accgctgcat ataactattg gcaaacaggt gattttgaaa attcatatct aaaagaagca
     4681 gaaaattttg ctcataagta cggcgtaaaa ttaactggtg attaaaaaat attaggagga
     4741 cttaacgatg atgcaatctt cgttaccaag caagacaata aagaacagca agaaaaaagc
     4801 aacagatacg tctcataaaa aaagtgctta tggattggtc acaccttttg ttattttctt
     4861 tattgtgacg attttgattc ccatcattat ctcgtttgct tttagtttta tgaaaattgg
     4921 ctactcattt gaatttgttg gatttgacaa ttatctagct atcttccgag atccattgtt
     4981 tattaaatct tacacgaatg ttttgattat catggcagga tcaattccaa taacgatgct
     5041 attagctatt tactttgctg ttttattgaa ttcagcacag ttaaaaggaa aaggattttt
     5101 tagaactgtc tattatattc caaccattac atcaacggtg gctgtagctt ccgtattcat
     5161 gacttttttc aatccgactg ggttattcaa tggatttttg aatgcgctag gaattaacgg
     5221 tgtacagtgg ttaacaaatc ctttttggat acgaatatca atgatcatca cgatgatttg
     5281 gcttagtgta ggatataaca ctattttatt tttagctggt cttcaaggga tttctaaaga
     5341 gatatacgaa agtgctgaaa tagatggagc atcgaaattt cggcaattct ttttattaac
     5401 gatccccatg ctaaagccaa tcattttaat ggccacagtt ttagccacta tcaatggctt
     5461 gggtaatttc aatatcccaa atatattctt tgggacttcc aatggaccag aaaattcagc
     5521 tttggtcgta ggagtcaatt tatataaaac aagttttgaa atggttgatt ttggaaaagc
     5581 ctctgctatt gcctggacga tggtgtttgt atctgttata ttatcggcta ttcaatttaa
     5641 attcggaggt gataaaaatg actaaacaaa agatacaaag cagaattttt acgtacgtca
     5701 ttattgtgtt tggtgcctta atatttttga tgccatattt atatatgatt gtagcttcaa
     5761 cgcaaagtaa tcaagaaatt ttaagtggcg gaatcaattt caagtttggg gatatgctat
     5821 taaaaaactg gcaagccatc atggcgagat ataattatcc cttgattatt tggaattcga
     5881 ttgttattgc tgtaatcagt acagttttag ctacagccag ttctacaatg gcgggttatg
     5941 cattagcaaa gtatcgtttt atggggaata aactgttgtt caatacagtt atgctatcta
     6001 ggatggtgcc tttttttacc acattgattc ctttatttta cattatgagt cgtttaggat
     6061 tatcgaatac ttatgcaggt gtgatcatcc cttcgattgc cagtacaact tcagtgttta
     6121 tgatgcgaca atatagcagt caatttccta cagcactgat ggaggctgcc agaatcgatg
     6181 gtgccaatga gtgggtgatt tttacgaaaa tcgctgtacc gattttatca cctacgatta
     6241 ttactagtgg tttacttatc tttatgggaa gttggaatca atatctattt ccattagtca
     6301 tgctttcaga taaagataaa tatacggttc ccttaattat caaaaatatg acggtttcta
     6361 gtacaggtga gccaattaat tatggcgcaa ttatgctaat tttagcaact tcagtgatcc
     6421 caatggtctt gatttatgtg tgggcgcagt ctaaatttaa ggagaatgac attggagctg
     6481 caaataagta aaaaaaataa cgaatgttaa ccatctagtt cgttctagga gcaactccac
     6541 attcataaaa attaaaagaa tggcgggata tccatgaatg aacagacgaa ggaatggtca
     6601 agaaaaattt tgaatgtagc ttctgaaaag atagatgcgg aattagacag aatggggaat
     6661 aaaattccat atatttctta caacggaaaa tatacagacg taataaagga cagaggaatc
     6721 gactggtgga ccaatggttt ttggagtggt attttatggc agctctttca caagacaaaa
     6781 cgagaaaagt tcaaagaggc agcaatacaa caagaacaat tattagaatc tgccctgtac
     6841 catttttcag acgttcatca tgatgtaggt tttttattct taccatcggc tattgcacat
     6901 tatcaacagt ctcaaaacaa acatagtcga caactagggt tacatgcagc tacggtactt
     6961 gctggacgct ataatatttc agggaactat ttagtagcat ggaatgacca taaacctggt
     7021 tggatgatta ttgatagtat gatgaattta ccattactgt attgggcttc gagggaaact
     7081 ggtgatccga ggttctctaa aattgctcgg cagcatgcag atacaacagc taagtatcta
     7141 gtgaggaaag atggatcaac cgggcatatc gcagaatttg atgcagaatc agggaaatat
     7201 attcggttac ttggcgggca aggatacaat gagaattctt gttggagcag aggaaatgca
     7261 tgggctttat atggattcgc gttaagttat cgttacacaa aaaatccgta ctatctagct
     7321 atagcagaaa agatagcagt aaattttatt cagaaaatcg aaaaaactgg ttatattcct
     7381 ctcattgatt ttgctgtaaa agattcgaat attgatacca gtgctggagt atgcgctgca
     7441 tgcggtcttc tggaattagc aggatatgtt tcctctgtac gatcaaaaat gtatcatgaa
     7501 gctgctatca atatactcca aaagacagaa aagcactatg caaattggaa tatggatgaa
     7561 gatgggatca ttggaggcgg agcagaagca taccatagag aactgactta taatgtgcca
     7621 ctgatctatt ctgattattt ttttattgaa ggcttacttc gattagaaca gtcggaatta
     7681 gctatttggt agtaaaaaga ggagaaaata caatgaaaca tccagtacca ctattaagga
     7741 ccagacagga ttactttgac ttatttaaaa agataaatca accactccag ccgttttatc
     7801 gagcaagtgg cgcacaaatt gattatatac atcaaggggt aggatatgga aataaaattg
     7861 caggaatgga aggattctct cgggttttat ggggagcggg gcccgcaatt gaccaattag
     7921 atgaacgatg gttgaaatta attctatcag gaataaaagc tggaacagat ccttcccatc
     7981 ccgattattg gggagaaata catgaaagag accagcgtat ggtagaaatg cccgcaatgt
     8041 tattagcgtt atatcatcat gaacaattat tatggaaaaa attagataca ggagaaaaaa
     8101 gccagattat tcattggttc tcgcaaattt ttgaatatga atgtgcagat ggtaattggc
     8161 aattttttaa gataattgtc ggaacaatta tccaaaaatt tggttatcca gttaaagaat
     8221 cagcactgaa agaagcattt gataatatag aaaattgtta tcttcaaaat ggctggtatc
     8281 gagacagttc aagaggtcgc caagattatt ataatccttt tgcatttcat tattatggtt
     8341 tgatttatag cgtactagaa ccagaaaagc ccattagcca gatatataag aaccgagcta
     8401 ttgatttttc tagagactat attcattttt ttgcggaaga tggtgcaaat gtgccttttg
     8461 gtcgaagcat gatttatcgt tttgcagttt caagcttttg gtcagctatg ttgtgggccg
     8521 atcttttgcc ttttaaatta ggtgaaatca aggggttagt caatcggaat ataagatggt
     8581 ggatgcaaaa agaaatattt gatgaaaaag gtatcctgaa tattggttat acctaccctc
     8641 aattgacatt gactgaaccc tataatagta cgttatctcc attatggctg aataagattt
     8701 ttttattgtt ggcgctacct gaagaccatg agtattggac ggctaaagaa atgcctatgc
     8761 ctattcgtga aggaactaaa cttctttcag aagccaattt gctcatacaa catgataatg
     8821 gacatacatt ttttttgaat gcgggacaat tagggccaaa tttccataca ttgaccaatg
     8881 aaaaatattt aaaatttgct tattctagtc aatttggttt ttcgataccg cgagcgaatc
     8941 aattgaaagc agaaatggca atggattcaa tgctagggat tcagcgagcg gacacatata
     9001 tcacgaccag ttttaagaat gagagcatca aaacctatgg acagttcatc gttcgaaata
     9061 atgtacgaga cattgtatgt aagaaagagg tacttgcctc tacatgggaa cctactttac
     9121 aggcaaaaat cagaacttgg cttattcctt ttgaaggctg gcagattcgc gtacacaaag
     9181 tagaattaga tacagaatat gttctatatg agacagggtt tgctattgaa tgttctcctg
     9241 agaaagaagg aataatcata gaagaagaca aggaaaacta tagggtgagt gaagctggct
     9301 tttcaggtat tatctgttta agtgacgata ctattaaacg aaaatccaca gctattatgg
     9361 gtttgcccaa tacaaacttg atgacatggg aaaacacttt tattcctgga ttagagggta
     9421 catttggaaa aggaacccat tggctcggaa caggagtggt tgctcatcaa gatcgggatt
     9481 atagtttaga agtatggaac aatcgtccca aaattgattt tgatgggaca accgggctaa
     9541 ctatccaaaa taaaaacaat aaaaaaagac taaaattatg ctaaaggctg gtggggaaat
     9601 gcttgataaa gtgatgtttg aagagataat acatccagaa aaatggataa atgaatgtta
     9661 taaagaatta atggaaaaag aatggaataa tgagatcgag cgttgtcgca gacacacgga
     9721 gaggttaatc aaacgtatca gtaacagtca gtatcaattc ccaagcgagt gtcctataaa
     9781 aggacgttat ccattaagag acaatattgg ttggacagaa ggattttgga caggaattaa
     9841 ttggttgtta tttgagaaga cgggtgatcc tttatttcaa caaacagctg aaaaagcaga
     9901 tatagatttt atccacagga ttgactgtca aattatcact aatcatcacg atcttggttt
     9961 tttgtattct ttatcaaccg tagcagatta taaaataacg ggaaatcgaa aaatgaagga
    10021 agcttcaatt gatgctgcag aaacattact tcagcgtttt tgggagaagg caggagttat
    10081 acaagcttgg ggagatccta gtgatccttc acaacaaggt agaatgatca tggattgttg
    10141 catgaatctt ccattattgt attgggcgag tgaagaaact ggaaatcaaa aatataaaaa
    10201 agctgctcag gctcatattc aaaatgcagc agattattta gtaagagaag atggttcaac
    10261 ttatcataca ttttatatgg atgtcaaaga tggaaaacca agatatggaa gtacgcatca
    10321 aggttatagt gataattcct gttgggctag aggccaagca tgggggattt acggttttgc
    10381 attaagttat cgttatttga aagaacaaaa atattttgat ttaagcaaaa tattagccaa
    10441 ttattttatg aatcggttgc cagaagatac catttgttat tgggatttga tctttgatga
    10501 ttctagcaga gaagaaaaag atacatctag tatggtgatc atggtttgtg gattattaga
    10561 attaatagaa tcaggtctat tagacaaaac agaaaagaac ttataccagt ctgctgtttg
    10621 gaaaattatg cgacaattga aagaaagata tgctacaacg gaagaagaag atggcttttt
    10681 aacacagtct gtttataata agcccaaaaa taatggggta aatacacctt gtatttgggg
    10741 tgattactat tatttagaag ctttagtgag aatgactagt aattggtctt cttattggtg
    10801 aaaaaggtaa atatggaatt tttgtttgat aaaataaaaa aagaaaaacc aaaacagcat
    10861 gaatggtttc tgttttggtt ttttcgttaa ttttcatatt cttctaattc caagcttagt
    10921 tcttcccatt ccgtcaattt tgtttcttga tcttgtctag cagcttctaa atcttggttc
    10981 agctcattga gttttacgtg atcttccagg ttttctggcg cgaccatttc ttgttccaac
    11041 tgatcgatcc attcatcgat ccgcgccatt tcttcttcaa cctgagtaat ttttcgttga
    11101 aggctacgga taagcttttg ctgttctttg ctttggtaat aatcagattt gttcgtggga
    11161 gcaggagcag attctggctc atcttgtgcc aacaattcgg cgatttcttc ttcttcctgc
    11221 tttttctcta aataataatc atagtctcct agatagactt tgctgccatt ttcagagagt
    11281 tcgacgactt ttgtcgcgat ccgattgatg aaatatcggt catgggaaac aaaaagcagt
    11341 gtgccgtcat aatcgatcaa tgcattttct aatacttctt tgttgtcaat atctaaatgg
    11401 tttgttggtt catccaaaat caaaaaattt tctttgttca tcgctaactt ggctaaagca
    11461 acccgtgctt tttcaccgcc acttagcaga gggattggtt tttctacatc ttcgccagaa
    11521 aataagaaag cacctaaagc acttcggatc tctttttctg gagtggtagg atgctcatcc
    11581 cacaattctg ctaggatcgt cttgtttgta tgcagatcag cttgaccttg atcgtaatag
    11641 ccgatggtga catttgtccc tagcgtttct tttccacgga taaaagggat ctggtgaatg
    11701 attgatttca gcaacgtcga tttcccgata ccattcggac ctactagagc aatcgcttct
    11761 tgacgacgga tatctagatt gattggttca gataaggtga cattatcata tccgatagcg
    11821 gcatcttcga tttgcaagac tacatttcca gaaggctttt ctatactgaa tagaaagttt
    11881 gcttgttttt catccccttg aggacgatcc agccggtcca ttttttctaa tgtctttctg
    11941 cggctttgcg ctcgttttgt ggtagaggcg cgaacaaggt tccgagcaac gaagtcttct
    12001 aatttatgga tttctgtttg ctgcttttca taagccttcc attcacttgc taactgttct
    12061 gctttcaaat ctagatattt cgaatagtta cctttgtaat ggcgcatttt tcttctgctt
    12121 aattcataga cttcattgac tactttatct aaaaaataac ggtcatggga aacaatcaat
    12181 aatgcaccag tatagctttg cagataattc tcaagccagg aaagtgtctc gatatctaaa
    12241 tggttcgttg gttcatctag aatcaaaatg tcagggtgtt gcaaaagcat gcgagctaaa
    12301 gctaaacgtg tgcgctgtcc gcctgataaa gtatcgattt tctgatcata aaatgaagaa
    12361 tcgaatttaa acccatgcaa tacggaacga atttcatttt cataaccata gccgtttcga
    12421 tctgaaaaat cgtgttgcag ccggtcgtat tcttttaaat aagaactata agcaggtgtg
    12481 tctggcgtac cttcgctaat gaaaatctct agctcgcgca tccgctcttc catttgtcta
    12541 acttgttcaa aagctttcag catctcgttc caaactgttt cattggaatc aagtcctgtg
    12601 tcctgagcga ggtatccgag agtcgctgtt ttatttttag cgatctttcc ttcatcaggt
    12661 gcttcaattc cagcaatgat ctttaataaa gtcgattttc cagcgccatt tctgccaact
    12721 aaagcgacac gagcgcctgt actgatttct aaatgtatgt tttcaaataa gacttctgca
    12781 ccaaaatggc gagcaatctg attggcttgt aataatatca tggaatcctc ttttctactt
    12841 tgtgaattct cctcaaataa aaaactattt ttcaattagt agtctaccat aaattccatt
    12901 atactgcgag atttgcagaa atgataaata aatgaataaa gaataaaatt tcacaatatc
    12961 tgagcaatgg aattgatttt ttcctataaa tactgctatg atggagaaat caaagatgta
    13021 attagacaat acgtggaggt catttcgtga aagatcatat tattccaaag gcgacagcta
    13081 aaagactgcc tttgtattat cgctatttaa ggattttaaa taatgctgga aagaaaaaag
    13141 tgtcttcaac tgaattaagt gaagccgttc aagtagatag tgcaacgatc cgtcgagatt
    13201 tttcttattt tggcgaatta ggaaaacgtg ggtatggtta tgatgtagaa gatcttatgc
    13261 acttttttgc aaagacatta aacgacgatc aattgacaaa tgttgcgctg atcggtgtag
    13321 ggaacttggg aagtgcttta ctaaaataca aattccatca aagtaatagc atacgtatca
    13381 gttgtgcttt tgatgtgaat gaggaaatcg ttgggcgcat cgtagacggt atccccgttt
    13441 atccaatgga agatatgtca gaacaaatca agatccaaca aatcgaagta gcaattttaa
    13501 cgatacccgc tgaaagagca caagaagtag tcaatcagtt aacggaagca ggaatcaaag
    13561 gaatcttgaa ctttaccgct gctcgattga atgctccgtc agatgtattg atccaaaatg
    13621 ttgatttgac gaatgaattg caaaccttga tctatttctt gcattctgac gcaaatgcgc
    13681 attccgaaaa tacagcagaa taaaaataaa aagcgattga acaaatgaag gcaaaacttt
    13741 cacttgttca atcgcttttt tctgtttgga caacgattat tttgttcgga agatttcttc
    13801 ataagaaagg gaatcatctt ctgctgtcag ttcatctagt agataacgga tttttttaaa
    13861 gtcgatgaac cgtgcttgcc gaaagacttc ttttccttga tgaaaaatca ggacaactgg
    13921 cgcagtcagc acttcaaatt tactagctac ttctggtgtt tcaaatgcat ccaaatgaag
    13981 tgccggaata tcataatgtg tgagaagttc ctctagtcgt ggacgaacag cgtgacaaac
    14041 actgcaatta ggcatcgaaa gataaatgac ggcaacggat gactgttgca gtatgtcttg
    14101 aacttcagtc aagttagtgg tttgtttcat ttttattctc ccttttatga tagaagtgat
    14161 atgtatgaga ccttaattta atgggaataa cagaaaaagt caattgaagt gctttggtaa
    14221 aaaataagag ttgtgtaaaa atttacagag caacttgttt tttttgaata aaagcgtata
    14281 tttgcaaagc gaatgaacta gaaataaaaa ggaggaaact catgttttct tttattccaa
    14341 attcggtttt gcagatgagt acgattttct tatcgatcgt tattgaagca ttacctttcg
    14401 tattattagg ctgtcttatc tcaggcgcct tacaagtatt tttgacccca gaacgtgtga
    14461 agagatggct tcctgaaaat cgtatcttct ctatttttac tggttcgatc ttaggatttt
    14521 tctttccttc atgtgaatgc ggcatcgtac cgatcgttca tcaatttgtt aaaaaaggcg
    14581 taccagttca cacagcgttt gcttttatgc tgactgctcc gatcatcaat ccaatcgtga
    14641 ttttttccac ttttatcgca tttggcaatt cttggcagat ggcaagctgg cgggtgatag
    14701 gcagcttttt tgttgccctt gtgattggtg tctggcttgc ctattttcaa aaagacgctg
    14761 tattgaaaga aaaaatcacg tctaaagtag cagaaaatca ccatcatcat gtccatgaag
    14821 aagaacaaag tgagaagaat gaaccaaaaa atcagctgat ccatcaaact gggcatgtgt
    14881 tgacacattc aatcgacgaa ttttttgata caggtcgtta tttgatcatt ggcggattaa
    14941 tcgcagctgc gatgcagact tatttaccaa ctagaattat gctaacgctc ggctcaacaa
    15001 agattttagc cattatcatc atgctgttat tggcctttac gatgtctctt tgctcagaag
    15061 cagatgcgtt tataggatct tctttgttaa gtctgttcgg cacagcacct gtagctgcct
    15121 ttttggtctt tggcccaatg gtcgatatca aaaatctact gatgatgaaa cgatatttta
    15181 caggacgctt tattttatcg ctgatcggac tgattgccct tagcgttatt ggattcacat
    15241 tatttattta ggagggaaaa tatgctgcgg tttttgattt tatctgggta tttcgaattg
    15301 atgatgtact tgcaagtttc tggcaaactc gatcaatata tcaatgtcca ttatcgctac
    15361 ttagctattc tttcaatgat tttatctgct cttttggctt tagttcagct gtatttgtgg
    15421 gtcaaaaacg gaaaagcaga agaaaaggca cacgagcacg atcatgacca tgggttgtca
    15481 aaaccttatc aacgtggaat cgcttatgta ctgctagctt tgccagtaat cgtggggacg
    15541 ttgtttccaa cagttagtct cgacactacg atcgtagaag ccaaaggatt taatttccca
    15601 gtaagtaaag aatcagtagg ggatccggag atgcagacac aatacttaaa gccggatacc
    15661 agtatttatt tcaacaaatc agactactta gaccaaatga atgagttgaa agaaaagtat
    15721 ggggataagc aaactatcaa gatcacagat gaaaactatt tagaagttat ggagctaatt
    15781 tataattacc ctagcgaatt cattggcaaa aaaatcagct atgaaggatt tgtttaccaa
    15841 acaccgaacg atagcaatac agatatcttc ttgttccgat tcggcattat ccattgtgtg
    15901 gcagattcag gagtctttgg tttgttgacg catatgccgg aaggagtaac ggttaaaaat
    15961 gatgaatggt ataaaataga aggaaccatc caatcagact attatcaacc attcaagcgt
    16021 gaaatcccat ctgtagttgt tacaaacgct gagaaagtct ctgctccgaa aaatcagtat
    16081 gtgtatcgtt ctttttaaaa gaacaaaata aataaacata gctcagacag ctgacacgca
    16141 aggacgtcgg ttgtctggct ttttttgcat gatgtattca tttgtttgat atttatttta
    16201 gaagcagcat cctgaaagta tttgatatcg gtttcaaagg tgttggaaaa gattgtgaag
    16261 agaattacaa tttattccta acatgtatgt tgaaaagttg tatgaaatga ttttgatagt
    16321 aaaatatcga gtggaggtac tttttatggt aacgcgtata tttattttgg atgatagttt
    16381 ggtttttgaa aaaatgctag tagaaatttt ggaagaatcc agaattttat taagtccttg
    16441 gaaatttgag atcgttcagg gattgaacgt tatacaattt gttgaattca ttaaaaataa
    16501 tgaaatctat tcctcagata tttttttcct agacatcgat ttgaacgcct attatagcgg
    16561 tatcgaacta ggcgaaatgc ttagagaaaa gaatgaaaag tgtaaaattg tttatctaac
    16621 gtctcatccg aataaagcaa taactgttat taatcgaaag attacgccta gtggttattt
    16681 gataaaagaa ttcacttatg aaaaaaataa aaaaagcatc caaagttact tattgaaaga
    16741 aaaagaaaac tatcctgttc aacatgctac gaaaaaaagg tggacaactg tccgttatgg
    16801 taatagcgat cactatatcc attacgatga aatcctttat ctaatgagca tgccaggtta
    16861 taaaaataaa ataggcctag tattgaaaga tgaagagatt ctcgtaaacg gcacaattaa
    16921 aaaatataaa aaatcactcg aatatgagta tttatgtaaa gatttaaaag cttatatcat
    16981 taatactgaa aacattacat ctattagcag agtaaacgaa atagtaacat ttgcaaatgg
    17041 agaacaacta gagatgggaa agagaagtat tgataaacta aagaatttta tgcaagaaaa
    17101 gatagaaaat gaatcatttt aaagaaaaca aagactcata tcttacctgt tagaagagtg
    17161 ttttcctgta gaagagaaca acccaagtag cagcctagtc gtttctatcc ttttttgtta
    17221 tgcactcttt ttgacattta ctccaccaat aacgaagggt acaataaaaa gtaataacaa
    17281 acaaaaggag tacagaaatg attgaattca tcaatgtaag taaaagttac gggaaaaaac
    17341 aagcattaaa agacttgtct ctctcgataa gacaagggga aatttttgga tttttaggac
    17401 ataatggtgc cggaaaatca actacgatta aaagtttagt tagtattatt gaaccatcat
    17461 cgggaacgat tttagtagat ggaatgaaat tgacggaaaa tcgattgagt atcaaacaaa
    17521 aaatcggtta tgtgcctgat tccccagata tttttttaca attgacggct ggagaatatt
    17581 gggacttgat ttcagctgcc tatgaattag acacacaaaa aaaagaaaag cgtttagcag
    17641 aattgacagc gctttttgat atgtatagtc atcaaaatga aacaatcgca agtttttcac
    17701 atggaatgcg tcaaaaaacg attttgatcg gcacgttgct gccagatcca gatatttggg
    17761 tattggatga acctttgcaa ggacttgatc ctcaagcagc atttgatttg aaagaaatga
    17821 tgaaggctca tgccgcaaaa ggaaaaacag tcattttttc tacacatgta ttggataccg
    17881 cacaacagtt atgcgataaa ctggctattt tgaagaaagg tgaattgatt tatcaggggg
    17941 cagttagtga attattgaat ggctcacctg atgaaacgct agaaaagatt tatttgaaaa
    18001 tggctggaag gcaagcgaca ggagatggac cgtatgtata agcgacaatt attagaatta
    18061 attcgagtta atcttttata tgttaatcca cagctcacga ataaagcaag agagaaagga
    18121 aaaaagggaa agcgattaac tatctatctt ttgtctcaaa atcttttttc agggctgatt
    18181 tttttactga tttacggatt tgctatgttt gctatgaact ttgttaaatt gccaggtttc
    18241 tttacttatt acgtggcact ttttggtatg ttaggtttaa ctcaaagtat atcagtcatt
    18301 tataatatct tttttgaagg aaatgacctg caagtatttt tgcctctgcc ttttggacaa
    18361 gaacaggttt tttcagcaaa gattttggta gttgctttga ccatcattcc ttttgttttt
    18421 ccgcttctag tcatgtttat tttaaccgga tggcgagctg atctagggat tttgcttact
    18481 atcattatct caatcctttt gttttctcta tttttgatta ttcttttttg tctggctagt
    18541 ttgattgttt ttggtttggc tcgaacagca gtgtttaaaa aacatagaaa aacagtttct
    18601 agtatcttgc ttggcagctc gatgctgatc gcatttgctg gaatcatgtg gatgaatcat
    18661 caaacgggga ctattgaaaa tgagttaaca gatcggcatc cgatttcgat attattgcca
    18721 ttctatgatg ctgccagtca gccactttct caacaaggtt tattgggttg gggaatacta
    18781 gctatcacgg ctctgggatt tttccttgct gtaaaacagc tgatagtacc aaagcttaca
    18841 gagcaactga ctgattcaaa cagtgagttc aaaataaaaa gaacccataa aaagaaccaa
    18901 aatgtgcatc agcttttatt tagttacaat gctcaattag taaaagaacc taatttgatt
    18961 atgcaagttc tttcttcttc cttgttaact ccaatcattt ttattcttgc ttttgcccta
    19021 ggaggcgaaa taaaattaac tgatttagat aataagttaa tcggtgttgt tttcctggta
    19081 gggatcgcat tggctttctt aacagttaat cagacttctt ttatcagcaa tcttatttct
    19141 ttggatcaag aaaattttct gtttatccgt tctttgccaa tctctatgaa ccaatattta
    19201 aaagaaaagt tcagattcgg atggatattg cagagttttt taactggtgg gatcgcatta
    19261 ttaagcggac tgtcttttca gctgcctttg ttttttatcc ctagcttgct atttggttct
    19321 ttattcggct gctacttatt gtcactacgt tatttcgcta gagattatcg gttgctgctg
    19381 ctgaactgga ccaatattaa ccaattattt aacagaggtt caggaagttt gggtttagtc
    19441 gcaactatga tgggttcatt gatcatcagt attattctta tcgtcttata cggaatgttg
    19501 gctttgtttt atccattttg gttagtgaat attcctgtga tcggtttagt tctaatactt
    19561 tccgctctat ggatcgttta ttatcaacga acgttttgga aaaaatttga ataaagaaga
    19621 ggggccgtga caaaaatcat gtcgcagccc cttttttaca gatagagggt gttcaaaagt
    19681 cagtttctca gtattaagtc aattttatgt aaaaatgtga gaagctattt ttacaaaact
    19741 ttttttaata ctcataatta cttcttattg ctcctgcggt tacttgtcgc aatgtttgtg
    19801 agatattttg tcatcgctca aggctgaacg tctctttcac aaccttttct ttgttacact
    19861 tcgtttattt aaaaagccgt ttttttcgtt tcatcatgat tgcgtcacgc tttactttga
    19921 aattacggat gttatggtta aagacttctg ataatacaag acctaaagcg attgctccag
    19981 caatcataat tgcttggacc gcataatgag ccgcttctcg ataggattca gtaacgagat
    20041 ttcgaaccgc ttgataagct aaaccaccag ggactagagg aaccatcccg ggaatattga
    20101 aaatcgttac gggcattttc aaacgtttag agaaaagatc gctgatgaat gctactccta
    20161 aagaaccaag caatgaacca aaagcagcag atccgcctat ttgaacacag atccagtaga
    20221 tcatccagcc aaaagcacca gaaagaccac aacaaatcaa tgaacgccta ggtacatttg
    20281 taataacggc aaatgccgca gtcgctaaaa aactaaaaga aaactgaata aatatcgtcc
    20341 ccatacttgt gttcctttcc taataaaaaa gctggaaaat aaaagcaatc gcaaaaccga
    20401 tcatcgtagc agtcatcatc gcttctgttc cgcgagaaac tcctgagaca taatgtccag
    20461 ctagcaaatc acggatagcg ttcgtaattt gaactccagg aactaaaggc atcacacatc
    20521 cgataatgat tagatcctga ttgcttccta agccaaaacg tacgctgtag atagcggcta
    20581 tgccaatcaa taaagaagat aaaaattccg ataaaaattt gattctaaaa aatttcaaac
    20641 tatatagata agctgcgtat cccaatcctc caatgactaa agtcacaggt aaatcggtca
    20701 tctttccgcc aaataacacc ataattgttc cactgatcac tgccgcgcta acgatttgca
    20761 accagacagg aaagaaagaa cggtctcggt cgattgcttg cagttcgcag taaagttctt
    20821 ctaatgttag ctctgaagca acatatttac gtgaaagatc atttactttt actacttttt
    20881 ctaaattaat cgaacggttg gtaatttgtt ccattcggat ggtcgaggta cgatcaagac
    20941 caataaagag accggtttga gtgacatagc tgaccaaacg gaaatttcca gaagctaaag
    21001 caattcgact catcgtatct tctacccgat acatctccgc attgctttcc atcatgattt
    21061 tcccagcgag taaacaagtg tccagcaaca gatctaattc ttttcccgtc atagcatctt
    21121 ctccaataat tgattgatta gttttatttt actacaaaac ataccagaag cgtaaagaat
    21181 aaaaaaactt gaggaaggaa taaaagaggc gtatactgtt tttgtattgc gggtgtagtt
    21241 tagtggtaaa atcccagctt cccaagctga tgtcgcgggt tcgattcccg tcacccgctt
    21301 aaaataggtt gtgaaaaagc tgctctgcaa caagtaataa gaacagccaa gcaaaaacaa
    21361 cttcttatgt ttttaacttg gatggactta ttaccgcaga tgcaagcttt tgcgcaccgt
    21421 ttaccaagcg gttgtgaaat cagtgtattg tcttgagtat gaagaaaatt tttgaataat
    21481 aataaatacc ttacagatag agtggtgact gattagagac gaggaatccg tctctttttt
    21541 gtatttttaa gccatcttaa aacaggtttt attttttgct gtttctattt ctttctagta
    21601 tttatttata ggggaacata tgttaagatt tagggagctg ttagtaaagg agtaaagaaa
    21661 tgagcaaaaa aacaaccaag gcgatcgtgg ggatcgtcgc tgctgtgatt gcaggggcat
    21721 tcggtgtttc caccacacaa aaagattcag atatctttca gcagattaca actatttttg
    21781 attccacacc acaagcttct caagtagcgg atgtgccaga atatgatgga aaacatcaag
    21841 aaatagaaat caatgggaat cagccggaat ttacaaaaga ggatcttagc ctttccaaag
    21901 gaacatggga aagctattca aatattgata aattgaacag agtaggacaa gccaatgcta
    21961 tgcttggaaa agatttgttc cctactgaaa agagagagcc tttgtatatt gacccgacag
    22021 gttggaaaca aaagaaatta agtgacgggc aatggttata taatcgcagc catttaattg
    22081 gtttccagct gactggtcaa aataacaaca ttaaaaactt gatgacaggg acacgttcgt
    22141 tgaatgctcc atacatgctt gctcacgaaa atgatattgc ggcatatatc aaagaaacaa
    22201 atcatcatgt acgctaccgt gtcactcctc attttgaggg gaatgaactg gtagccaggg
    22261 gagtgcaatt ggaagcagaa agcattgaag acaaaaaaat tgaattcaat gtctttatct
    22321 acaatgttca agatggctac acgatcaatt atgagacagg acaagcaaca aaaacaaaaa
    22381 attagtagca gctattcgaa ttttttatga atattatgaa aaaattgtgt aaaaacatac
    22441 attcaaagaa atatagcgta tactttatga aaagagtact tttgataaag ctacagaaaa
    22501 aaggaaaaaa acatacaaat agtgtttctt aatttattcg gaagtttgga atatttgttt
    22561 gtagttttcc ctttcttcga gtaaaataag gttgtagaag gtaagctgga attaccttgc
    22621 gggaaagagg tgtagaatca tgggttttac agatgaaacc gtacgttttg gttttgacga
    22681 tagtcgcaaa aaagaagtga gcgaaacatt agcgattgtt tatcgggctt tggaagaaaa
    22741 aggctacaat ccaatcaatc agattgtcgg ctacttgctt tctggagacc cgtcctacat
    22801 tcctcgttat cgtgatgctc gaaatttgat tcgccgtcac gaacgcgatg agatcatgga
    22861 agtaattgtc aaggactacc tctcaaatca tggagtgaat ttatgagagt aatgggcttg
    22921 gatgtcggtt ctaagacagt aggtgttgct atcagtgacc cctttggctg gacagctcaa
    22981 ggagtagaga tcattcggat caatgaagca gaagaagagt ttggctttga tcggttgaag
    23041 gaattagtag cacaatatga agtagaccgg tttgtagttg gattacctaa aaatatgaac
    23101 aattccatcg gaccaagggc agaagcttcc atgtcatacg gagaaaagat caaagaacta
    23161 ttctccttgc cagttgatta tcaagatgaa cgattaacca ctgttcaggc agaacgtatg
    23221 ctagtagagc aggcaaatac ttcaagagcc aaacgaaaaa aagtcatcga taaattagca
    23281 gctgtgatga tcttacaaaa ttatttagac ggctcaggta agcaattatt ttaataataa
    23341 aagaaaagag gtaatcttat gacagaacat aaccattccc acgaccatga aggacacgaa
    23401 cacatcacat tggtggatga ccaaggaaat gaaacattat atgaaatcct actaacagtt
    23461 gacggacaag aagaatttgg acgtaactat gttcttttat atcctgctgg tgtttcagaa
    23521 gatgaagatg tagaattaca agcttatgca tacatcgaaa acgaagatgg aacagaaggc
    23581 gagttagaac aaatcgaaac agacgcagaa tgggacatga ttgaagaagt attcaataca
    23641 ttcatggcgg aagaagaaga atagactata aagctaggag aaaccttgat atgatagggt
    23701 ttctcctttt tttatttttt actgtatgcc atattgtatg ccatctagtc aatatttaag
    23761 tgttgtacta atttttcaac agtcttttct ttcgtttctt ttgccaagtg accgtaacaa
    23821 tcgatcgtct gactaatttt tgtatgccgt aatctagttt gaacttctac catagtagct
    23881 ccagcgtcca agagcattga agcatgagtg tgtcttgcta catgcacacc gagaaatgga
    23941 accatagctt tttcacaaat agtaatcaat cttgcataaa tagcgtggtg tgtgattagt
    24001 tctttataga taccacaaaa aatcatagtc ggatcagtta caccaagtgt cagcatatat
    24061 ttccgctgat taatctgcca tttttttaat atagaaattg ttctttcatc tagtggaaga
    24121 accccagcac tacaatcagt tttaggatca ctgattttat agccattttt ggattggctt
    24181 agtgttttat tgatggtgac cgtattttct tgaaaatcaa tgtctgacca attcaatgca
    24241 agggcttcac tgatcctaac cccgctataa aagagaaagc gtagtaacgt tttatcaaag
    24301 tcgtttcgat aagtttcagg tttgctgttt aggtaatcaa acaaggtgat cagttgttct
    24361 ttactgtaaa ctttgacctt ttctttatgc ttagtggtgg ttcttttagg cattaatacg
    24421 ttgtctagtg gattagtctc aataatccca agattgatag cgtagctaaa aatacgctta
    24481 gaagttgaat gaagtacctt gtattggtca gtagtttcag cccagctatt tacaatttgt
    24541 tgggcttttt ttaccgtgac ttcattcaca cgaagatttc catattttgg aagaatccac
    24601 tttctaaact tgatttcagt tttcatgaag gtggcttctc ggacagtggt tttatatgtt
    24661 tctagccaca agtcataaac ttctttaaac gtttcgttgt tcgctttttt aataccgttt
    24721 ttatcgtagt ccacttgcaa gcgtgacaag gcaagctggg cttctttttt tgttttgtaa
    24781 cctcgtctac gaaccttatc aggtttgcca gtcattttgt tcattccaag ataggcttca
    24841 tagagccaaa atttaccttt tttagtttca tattgcttga atgttgccat aatagttttc
    24901 cctccatagt gtagcaagcc gtgggggcgg ttggaggagg cagtttatta ttattttgaa
    24961 tagtgtttat ttagctcagt aacaagagct gtgaactctt ttagaagatc attttcataa
    25021 aattcttgat actctttttt ctcatctgta tttttttctg aatcattaat taatgagtca
    25081 tatcgtaaaa gcgtatttag aagagctgcg agataagcaa ttggggtact cccgtcagga
    25141 aattcaattc gagatcctgt tttaagatat tttattgcgt ttgttaaata aatcttctgt
    25201 gagacagtca ggttatcttc ttcgatgtta ttgatagcat tagaaagatt agaatcaatt
    25261 atagagttat ttttttcaat agtttttttc aattgctttt caagcacatt tcgcttaatt
    25321 tcgggcatca tatgcatatc tcttaatgta taagatccgt ttaatagata ggtagtggat
    25381 acatctaata cctttgaaag ttgtttaagc ctggtgttat tgggaagatt atagccattt
    25441 tcccaattac taacggcacc tttactggcc ggtggggata atttacctcc aagttgttcc
    25501 attgagagtc ccttttcaat tctagccagt ctaattcttt gtcctgtctc cactgcttcg
    25561 gggtattttt ttctagccac attttcacca ccattcatat attttctcta ctatatcacg
    25621 atttaaatat gtgtgaaaca taaaagttca aaaaagtatg ttaaaattct tgcaaatgaa
    25681 aaggtatgat ggtatattga gtttataaga ggtatagaaa tgtattcaag agcctcttgc
    25741 atttttttaa aatctttgta tagaaatgta tgctaacgag gggggataaa tatggaatta
    25801 aaaattgaca aactcacgct tgatgatcca gcttttaaaa ttattgacga tcgagttgtt
    25861 caacaagtag agcaaactca aggaacgtta ctttcattat tagaaaaaaa gtaccagttt
    25921 ccaaaatata tgaacaaggc acaagctgct aagtatatga acgtttcata caatactatg
    25981 atgcagaaat atgttcctaa cggtttaaag ttgattatag ttgatggagt cgtaagaatt
    26041 tcacaagatg aatgtgatcg ctttatggaa gaataccaaa aataaacgca agccgtgggg
    26101 gcaaagggat taataggagg aaataataat ggaatcgaca caaaataaag caatcgaaaa
    26161 agtattatca acaattctta cagaagacac agcggcagaa ttagcaaact tggaaggcaa
    26221 agcgctagaa gaaacgtttg aatgtttgta cgaacaaatg gactatcaaa aattgctacc
    26281 acaagaacca acggtaagcg gagtattgcg tggcttgaac gatttagtac aagcagagtt
    26341 taaagaacga ctttctattg aagagtatca agaaattttg tatcagcaag ttgagttgtt
    26401 agcgagcttg ctagggcttg aactggagga cgttgaatga aaactgaaat ttggaacgga
    26461 cacattataa gatttgtcga tattaatgat gaatggtggg cagtggcgaa agatgttgcg
    26521 gaagcgttag gtcttaaaca ggttactaga gccattcact ctttgcctaa agatggggtt
    26581 actactagta aggtcatcga ttcattgggc agaacacaag atgtaaacat catcaacgaa
    26641 aaaaaatatt taccgcatgg cattcaaaag ccgtaaaaaa gaagccgagg catttcaaga
    26701 ctggattttc gacatcatca aagaactacg ccagtccaca ggacttgaag gctttcaagt
    26761 attccgcatg ctagacaaag aacaccaaaa agaagcaatg actaaattaa gccacgctat
    26821 tactgaacca aaaccagtag actacattaa agcgaatgtg atagccaata aagctgtatc
    26881 aactatttat ggtcattcca aaatggtaaa aaagaaagat atgactcctg aaatgttggt
    26941 tgatcgtgaa cctattttag atgagacagt agaattaatg actgttaaag aaaaatatgg
    27001 gttgcagttt tcagtgagtg agaaaattta taatcgttct gctgaattgc agacaactta
    27061 ggagcattaa catgatcgag aacaaagaaa aagccttatc cataacagtc ttggcggaca
    27121 ggataaaggc aacttaattg ggataaaacc cgatattctt tgttccgatt ataccatatt
    27181 aaaaaatcgg agggaaccat tatgaaacga aacttaatta taggaagcat tttaatcggc
    27241 ggaattttcg gcttattacc attaattgca aaaatagcta tctttgcagg attagcgtta
    27301 tatctcttca ctgcttatga cgagtacgac tatcaattaa gaactggagg gcataagtag
    27361 atgtacaaaa caaaactatt aaaccaactc gatagccttg aattagagga aattaatcaa
    27421 gggatcgctg aactagaaaa taatatcggg aaaacctact ttggaaattc attcaatgaa
    27481 aaactaacag ttttgtatgt actcaaaaaa catgcagaac acaaaataat ttgtcgagaa
    27541 atcaacgagc taaaaaatca gattttaacc gcatggttaa acattactga tatgcaagaa
    27601 gcaagggtga aaacatttaa tacatgggta aagtatcaga atcaattaaa aggtgctgaa
    27661 tttgttcggg atgggttgaa atacgaactt gagcagttga agctcatgga ggtgtctgaa
    27721 tgatttatac cagtattttg aaaaaggagg agaggtttat tggcaaataa ttatcaagca
    27781 gcaacggaat tacaaaagtc gggatggtca atttatccct tatctcctgg aactaaaatt
    27841 ccaataaaag gctctagtgg ttggaatgat gcaactaacg attctaatca aattaatgaa
    27901 tggtggacgg aagatgcaac tagaaatatt gggttaatgc ttgaagatca tcaaatggtg
    27961 gtagttgacc tagatcaaca ttctgaaaca cgaaacggcg ttgagaatta taaaaaactt
    28021 gcttcaatgt atgatccatt tccttctact tatacggaaa tcacaccagg taaaggaatc
    28081 catttcttct ttaaaattcc tgatggtgta attatccaac aagaaacagg tgcatttgct
    28141 gatatcttcg ggcgtgatga taaaggtaaa agtttaagcg ggattgatat tatcactaaa
    28201 ggagttccaa tagcgccaac tatgattatt tcaagaagtg ttgggagagc atatgaacct
    28261 attgaaaacg tatctctaaa taatattgca ccagctcccg attggctagt gaacctactg
    28321 ctaaaaaaac cgcaagaaat aaagactcaa taccgacccg tagcaaaaac agggacagca
    28381 aaaaaattag atatgattgt tcaaggcgct ggcgaaggta gtagaaacga tcatttaact
    28441 aagttatgcg gttggttact atggcacggt gtagataatc aaactttagc agaattgatt
    28501 tatacagcaa atgcgtacaa tgaaccaccg ctaaaagata aagaagtgaa tcaaattatt
    28561 cgatcgatga ttaaaaaaga tttgaggggg aaagctcatg gctcataagc ataaattaga
    28621 tagtatttta gactttcccg aagccagcga gcgtgaagac aatatcattg aattgaaaac
    28681 ctggatgtca cgattaagat gcaataaaga cgatcagatt aaaagtaaca gtgttgtgaa
    28741 tgcagaattg attttaacca atgatagcaa tttagctgga acaattgctt ataacgaatt
    28801 tagcggatac attcacctat taaaagattc tccttggatc aatcgtaccg ctggagaatg
    28861 ggaagacagt tttgaggatg ccttaacggc atatattgaa gaaaactaca atgtagtttt
    28921 tgatgacaac aaaatacaca aagcagtagt aaatgtggct agaaagaatg ttttcaaccc
    28981 agtaaaagaa cgtatcgaaa aagttaaatg ggatcaacag cctagactgg aaacactgtt
    29041 tattgacctt ttaggggtag acgacaacct ttacacacga gaagtaacaa aacgttggat
    29101 agtcggatca gtcgcacgta tctataaacc aggaataaag tttgagatcg ttccagtttt
    29161 ggatggaccg caagggattg gtaagagtac cgttccagca ttactttaca cggatgattt
    29221 tttcaccgat tcattagatt cgctaggtga aaagaaagat gattatatgc agcttcaagg
    29281 caatgtaatt attgaacttg gagaattatc ttcaatgaac aaaactaaaa ttgaacagat
    29341 aaaaaacttc atcagtgcca agatcgataa aattagacct ccttatggtc ggaatgtcat
    29401 agcttgggca aggcaatgtg tatttattgg aacgtcgaat gatgggcagt atttgaaaga
    29461 tgatacagga aaccgccgtt tttatccttt gccttgtaag aataagccaa agatgaatcc
    29521 gtttaaaaca aaggatgaat attttcttca agtgttagct gaagcaaagg tgctttttga
    29581 taaaggacaa cgaatctatt ttagtcccga tgaagataaa gaagtcttag aaattgcaaa
    29641 agactatcaa gaggatgcca agatggagaa tccaattaaa gaagcaatca ctaaatattt
    29701 ggaaatggaa atcccgtata aatgggaaga agctccagcg tgggcgagac gttcttatta
    29761 tcagaactat cctgacagta aatgtaatga gaaaaattta cagcatttct ataatggagc
    29821 tactatgcaa caagagtttt atttagttga tagcgtactc accgctgata ttttggaagc
    29881 tgtttttgat aaacaagcaa aggatttatt gaatggtcga tcagatgcag aaactaaaaa
    29941 gattgccttg attattagca gtattcctgg ttgggaacgg aagcaactgc caaaaagaaa
    30001 taaacgacga ggattttaca ataagtcaaa tgcctatgaa aataaaaatc gagctggaaa
    30061 gtacaaaaag taacgggtag taacgggtca gtaacaccta gcccgttact agtttaccct
    30121 tactgcccca agggatacag caatttggta acggggtaac accttatttc cttaaaactt
    30181 ttgaaatagt tagctaatat gctggggaat aatgttactg gattttaccc gttacctgtt
    30241 accaaaacgc tagaaccctt gtccccgttg ggattgagtg gtaacgggta cctgttacgt
    30301 aggtgttacc acgtgttacg aatcaaggag gaaagtaaat gctcaatatt atttcaacaa
    30361 acaaagcacc gaactttcaa tatacagatg aaatggatcg gtttctaatg aacacgctgg
    30421 catttagtgt gggattggta acagaagatt attccacatt tgatccagaa gtattaaaga
    30481 taatggaaga agaacctgat tggctgcagg agtcagtagc gtggtgtcaa tcgctagtag
    30541 tgggatcatt ggtagatagt ggcaactatg atgatacagg tgagctaatg gatgaattta
    30601 attgtctgct taacctatat gatcgagcga gacaacgaga gcttacatcg aatgaggata
    30661 atttgttttt aaacatccat gataagttct tggctttgct actaacagat gatgaattga
    30721 taactaattt attggaggta gaataattat gcatatggaa agtattagat acttcgatgg
    30781 tgagaaacac attgagtatt caaacactca agaagatgta gactttatta gttttgagga
    30841 agataaaatc actaaagtta attttaaaga cggaacgtgc ttgaagatag tttcgcctta
    30901 tattgaatac aaatcaaaat gggaacaaga tgattctgac gaacgagatc gctttggttg
    30961 gtaatctatg gcagttaaaa aacaatgtaa tcatgctgga tgtaaaacat tgattgatta
    31021 taggcagaag tattgtggga agcataaagc aaagcaaacg gcaattaagc gtgaagaaag
    31081 aaagcaaagc gaaggtaaat attttcaatt ctatcaaagt agaacatggc gaaaggcttc
    31141 atacttgtat cggttaaatc atccagtatg tgaggattgc ctagaagaag gcttgataag
    31201 gaaagctgat gttgtagatc acaaaattga actaaaagat gattggaata gacggttaga
    31261 tgaaactaat tttcgttctt tatgccatgc acaccataat tccaagacag ccaatgaaag
    31321 acaaagacga gaaaagagta ccctttgagt taagggggca tagtgtgaaa cttactgaca
    31381 atcgatgcct actcattttg gtacaaataa ccgttgtgaa aaggcataag ggtaattaca
    31441 aataacgatt acacttgtaa tcacaagtga aaaagtatat aatgaaagta ggagatttat
    31501 tgaaaaatac aattgttatt actgataaaa cagggaaaca gcgcaccatt gagttacctc
    31561 attttggtca agtgaccatt caaatgcaga acggaaaaat catttatata gataaattag
    31621 ataaagaaaa attctgatcg aaaaacgaag gaatgtgagc ttaattgctt acgttccttt
    31681 ttcttttgtc tgaaaggagg acaacatggg acaccctaaa atattacacg atacaaaagg
    31741 caatatatca agtgaagaaa aagcaatccg tgtggacgct agagaagaat tgttcaagca
    31801 gcaaccatta ataaatatca cgccccctga ctggatggca gcgagcgcta gaagtgaatg
    31861 gaatcgtatc gtaccaacat taaaaaaaga ttatccattg agtgaagcag attatggttc
    31921 attggtagcc tattgtttag cctttgctcg aatgaaaaca gccgaagccg agataagaaa
    31981 atcaggtacg tttatcacat gcgaaaacgg agtaaagaaa gccaatccag cggttcgggt
    32041 tcaatcacaa gctatgagtg atttgaaaaa acaagccacc tcactaggta tgaccttaga
    32101 atcacgatca aaactagctt tgaacaaggt taaaaatgat gaacccgaag acccgttcaa
    32161 agagttgatg aattcatgaa tgattacatt gagaaagtcc tatcaggtaa gctgattgca
    32221 cccaagaaaa ttatccaagc gtgtgagcgt catataagcg atttggagcg ttctaagtca
    32281 gatagcttcc cttatgtgtt cgatgaagaa caagccacca aagcgattaa attcattgag
    32341 ttgctaccat ctacggacgg taaagcaatc aagatgttag gatttcaaaa attcattcta
    32401 ggcagtcttt atggctggcg tactaaagaa gggaattaca ggcgattcaa tcgagcgttt
    32461 accagtatga gccgtaagaa tgggaaaacg tatatcgcaa gtggcatggc tgccaatgcg
    32521 ttgattatgg aacaagaacc agcagaagca aggcaagtat tgtttgtaag taacgctttg
    32581 aaacaagcta aattgggcta tgatatgctg tctaattcac ttagaaacgt ggtcaagtct
    32641 agtaagtttt taagaccaca actgaaaatt atgaactcta agattcagca cttgccctct
    32701 aattcgttcg ctatggcact ggctagtgaa accagcacgc tagatgggtt tgcaccaaca
    32761 accgcaattc ttgacgagtg gcacgaagca aaaactcgta aaacgtacaa cgtcattaag
    32821 tcaggaatga cccaacaaaa gaacggctta ttgtgtgtta ttagtaccgc tgggcttgat
    32881 ttaaacgttc ctatgtacga ggaatactta ttgttagatc gtgtgctaaa aggcgaagaa
    32941 caagccgaca ggtactttat agcgatatgg gaattggacg atcccgaaga aattcacgat
    33001 caagagaaat ggatcaaagc caatccgatt tttgaaagtg aagaaatcaa aaaagtaatg
    33061 attccaacca ttcaagatga tgtgaacctt gctttgaaac aaaataacct taattctgta
    33121 ttggtgaaaa acttcaattt atggagacaa gcgagtgagg acagctatat gattgctgaa
    33181 gactggcagg caaccgaagt agaaccacaa gatattacag gcaagcccgt ttatatcgga
    33241 gtggatttat ctaaaacaga tgatttaact agcgtttcat ggatcgtacc gctagataac
    33301 ggcgaacttt attgtgattc acatagcttt gtagccacca aatatgggct tcaagacaaa
    33361 gaaaagcgcg acggtttgcc ttatcgagaa ctagaaaaag ctggtgagtg ttccattact
    33421 caattagaaa gtggaatcgt ggactatgac caagtatttc agtttattca agatttgatt
    33481 caagaaaatg atttggaatg tatggggatt tgttatgacc cgtataacgc taattcgctt
    33541 atcagtaaag ctgaaaaagc caactaccca atgttagaag taagacaagg aacgattact
    33601 ctaaacgttc cgacccgaac ttttagagaa caagtttatg aaggcaacgt tattcacaat
    33661 aaaaatacga ttctcaccca tgcagtgaac aacgctattt taaaaacgga taacaacggc
    33721 attcagatta ataaatcaaa gaacagtaac aaaattgatc caatagctgc attaatcaat
    33781 gcctatgtgt ttgcaatgga ttacttcacc acaacggaag gagcgaaagc agacaatgaa
    33841 ttttatacaa gtgaagaatt ttctttctaa ttacattcat accgttcttt tacttcttgg
    33901 attggtgtgt gtgttggttg ctatcacctt actaacaaat gtctactatg gcttgttagc
    33961 gctgggcata gtgcttattg gggtagcggt catgctaaat acagaacaga agggaggtta
    34021 aaagatggca ttttttaaag cgagacaaaa tacaacggga gatcctttcc tacaacatgt
    34081 ggtatcaatc caatcggatg attacaccac cagctttaca agcgttcgtg cattaagaaa
    34141 tagtgatgtg tttgcagccg ttcgaattat tgctagtgat attgcttcaa gtccgattca
    34201 attggtcaaa aacaatatgc cacaagctga taatgaactg gtgaagttac taaacgagaa
    34261 acctaattca gaaatggatg gttggcattt aaagtttgct ttggcggtca atatgttgct
    34321 aaacggtaat agctttgcag agattaaacg caacggtgaa aaggtagaag aaattcactt
    34381 attacctaac tcaagtgtaa cggttactca attagataat ggtacgttgt cttatcagat
    34441 tggtgataaa aaaagacgtg tgaagtctag cgatattttg cacttcaaat atttcaccca
    34501 agatggttta acaggattac caccacttta tgcgttacgt gatgaactga aaattcaaca
    34561 agctggcaac cgcacattgc acaatttctt tactcgtggt gtcagtgggt caggtatttt
    34621 gaaggttcat aagtcagatt tagacggatc agcaaagaac gcaattcgtg aaaagtttga
    34681 agaagccaac ggttcaagta gtggagataa tgctcttaga acgatcattc ttgatgaaac
    34741 aatggactac aaaacattag aaataaacac cgatgttttg aagcttatca attccaatga
    34801 ttggaacaca aaacaaattg ccaaggcgtt tggtgtaccg attgagcgtt taggcgttga
    34861 aaatgaacat tctagcaccg ttcaaagtaa tctccagtat atccaaagta cgctgattca
    34921 ttactttaat gtgtttgtga gtgaattaga tacgaaactt gaaaccaata tccgctttaa
    34981 ttccgatcag ttactagaga ctgatcctga aacaaaagta aaaaatgtat tggatcaggt
    35041 caaagggtca cttctcacga ttaatgaggg gcggtcgaaa atggggctac cccccatgga
    35101 tggtggcgat cgtttactag caagtttgaa ctttacgtat ttagatacgt tggagaaata
    35161 tcaattaaaa gaacaggaag gagttacacc agttgaataa tgaagaagaa aaggaaaaac
    35221 ggctgacaga agaagctgag ctaacagccg attctcccaa agtagagaaa gaaaatgaaa
    35281 aacaaccaac agacggcaaa actatttcag gctatgcgtt gaaattcggg caaccgtcaa
    35341 aagatttagg cggctttgta gaagtgatta cacccgaagc attaaaagag gtggatttat
    35401 caaatgtgtt cttattatat ggacacgatt attcaaagcc actagctagt gtcaaagcag
    35461 gtacgttgaa attgaatgtc gatgatacag gattacattt tgaagcagag ctaaccgaca
    35521 cgacctattc aaatgatgtg tatgagaata tctcaaaagg ggttgttgat tctatgtcct
    35581 ttgggttcgt gcttggatta gattcattcg acaaaaaaga agatggcaca attgaacgat
    35641 caatagataa aatcaaagca cttaatgaaa ttagtgtcgt gaccgttccc gcttatgatt
    35701 catcaaatgt ccaagtaaat aagcgttctt acgaatcgtt tatgagtaac aaccaagcaa
    35761 aacaaacaaa caatagctta gaatccactt ctaaagcaca aaaggagagt aataacatgg
    35821 aaaaaacttt aatcgataac gaaaaaacag aattgcgtgg gtatgaagaa tatatccgtt
    35881 cacaaggcga agtgcgtgat ggagtcacta ctgtaaatgc agcggcagtt gttcccgaag
    35941 aagtaatcgg tgaagtcttt gatttgaaac gttcaaatta taacttagct caatatgcaa
    36001 cagtaaaaac agtatcaaat ggacaaggta aatatccagt agcaactaac caacaagcag
    36061 tgttagcaac aaaagctgaa cttgctgaaa ttggtgatat tgacgctgaa atgtttactt
    36121 cagttgatta taaagtagaa actcgtgctg gtaagattgc cttatcaaat gaggttgtgg
    36181 aagattcagc agtgaatatt gtacaagagg tcaaagatca gttagcgaaa ttggtagaaa
    36241 acactgacaa taagcatatc atggatttat taaaaacatt cactaagaaa acggctgcta
    36301 cgttggacga tttgaaacaa ctatacaatg tggcattaga cccagcatta aataaaatgg
    36361 taattctaaa ccaaagcgga tattaccacc tagatacatt gaaagattca gatggacgtt
    36421 acattttaca acccgatgtg acagcaccta gtggtaaatc attattcggt atgccagtag
    36481 tattgattgc agatacattg tttgccaatc ctaaagctgg aacattccct atgattatgg
    36541 gggatattgc acaatctatc tttgttgctc gtagaaatca agtaacgact caatgggaaa
    36601 aattcgatta ctactcacaa ggacttgcag tgatcgttcg caacgattat aagaaaattg
    36661 atcaaaatgc ttcagtgtat attgagttta cgccagttgt aacaccaaaa gtatagaaaa
    36721 atattgggcg gcggtttatc ccactgcctt tttttcatta ggagagataa aatggtaatt
    36781 ttggatagca taaaaaaaag tatgcggatc gatcacacta ttgatgatga ctttattcaa
    36841 caattgattg atacagcagg cgaatatata aaaagtgcta ttgatagtag cgcaacggat
    36901 aaagatatgg ataattatca gcaatttgat ttggcggtgt cattacttac tcaacattgg
    36961 tatttgaacc gtcaagaagc cagcagcgaa cggataccag taacggtaca agcattagta
    37021 caacaaatga gaggtgctta ttatgccaat cattaagaat gtaaatgaat tgactgagag
    37081 agtcaagttt aaaaagacaa aacgggtaaa agatgaagat gggcagatgg tggatagtga
    37141 agaaactgta tttgaatgtt gggctaatgt gcgttcacaa atgctaaaag acgtgcttgc
    37201 tagtgtaggt accattcttg aaggaacgtt gacgtttatt attcgatacg atcaagatta
    37261 tgaactaaca aacgatatga aagtagcttg gaaaaacaag agttataaaa ttatttcaat
    37321 caatgaagga acggcgttta aagattatac aacgatcata gctaaacaga tttcttagaa
    37381 tgattacact tgtaaacgtt gtgggtattt agtataatta aggtagtaaa tgaagggtta
    37441 gctgcctgaa ttttgcaaga cttagctagt cgaaatctat tgttggactg aaaattgtag
    37501 gtgtggttgc aaacatgctg gactaagaaa gatgatagat gatgaacgtt caattttaat
    37561 acaggcatgc taggactgat tggatggttt tggcaagctg attgtgtaga aatcaaagaa
    37621 cacgtctgtt gtggacgtgt tttttttgtt ataattcaaa agaggtgatt taatggacaa
    37681 agcagagttt acaaattttt attggaagta ttatctacat ttagaaaatg agtttattaa
    37741 taccacagat tttgtgatgc tcgatgagaa taatttcaaa acattctcta ttgaatatca
    37801 aaaactacta ctagcgattg gttcggagtg tgagattatt ttcaaagaac tttgcggatt
    37861 tgatagcagt agcaataaaa gcataactga ttttaaagct gttattaaat ctagcgaatt
    37921 aatgtgtttg gataatggtg ttagggttat gaattcttta acattgactt cactaaaacc
    37981 ttttggagat gggtggcctg aagatacacc agattggtgg aaaatatata acagagtaaa
    38041 acatggtcgt tcttcaaatt ataaggaagc aaatttggaa aatgtgttgt atgctttagc
    38101 aagtctatat ttattagagg aatatttgca taagaaagta atactagaag gtgaagtaga
    38161 ctttataagt ccagagtcaa atctatttac gttatcttgg gaaagaaaac attcgtcgat
    38221 gcaaaaagtg acgtttgaaa aagtggattc aaattatgta gctccactca ttgattttaa
    38281 agaacaagaa gaaatttaaa aacccccacg gcttattgaa gtttttgtat gccatattgt
    38341 atgccatttg gtttaaatcg cttgaaaaat agtgatagat aactctaatt catttagtca
    38401 taaacgctgt tttgataacc tttatagttc tttgatatgg gtttctcatt catggcggaa
    38461 gaagaagaat agaacaaaag aatgaattaa taagatataa aaaaagggat tgtgacaaac
    38521 gtcttgtcac aatccctttt tccaaataaa cgatgttcaa tcagctgccc ctcggcattc
    38581 gctcgaaaaa cggcgaaata tgaagaacta ttttgccatt tgtttctcta ataatcaggt
    38641 caaaacgttg acttcacagt ctcttcctta aacggtgttc tcctgccaac tcctcggtca
    38701 caagtcacaa tattcaacaa acatgagaag ctgttttttg aaattgttcc ttgtgactcg
    38761 gagctgaacg gcaggctcac gacctctttc ttaaacggtg ttcaaaagct tgcatctgcg
    38821 gtaataagtt caaccaaacg aaaattatga ggagctattt ttgtttggct gttcttatta
    38881 cttgatgcag gacagctttt tcacaacctc ttttcgttta gcactaaatt tccttaaaaa
    38941 gtagaaaagc tttcgaagcc tcgtttgttt cttttactgt ataataaaag aaaagagtaa
    39001 caatcgctaa aagatataaa caagagaaag gaaatacaag atgattggtc tgatttattt
    39061 tgtggtgatc gttctggcga acacagttgg cgctatttcc gggatgggtg gaggcgtgtt
    39121 gatcaaaccg attcttgatc ttatcggcgc ccattctgtt gcagggattt ctttttactc
    39181 aacagttgcg gtattcacga tgtccattgt ttcgactgtg cgacaagtat caagcgggaa
    39241 atcactgaat tggcagattg tcggttgggt atctagtgga gctgttgttg gaggagtagt
    39301 cggcaacatt gtattcgaag tttttttaca gttatttgaa aacgagaagc atgtgcagct
    39361 gatccaaatt tttttgacgg tattgacctt ggtttttgcg ttcttctaca ccaagcatca
    39421 tcagccaaaa tttcatttga cgtcatggac ttggtacctt atatgtgggg gggttctggg
    39481 ctttttagct agttttttag gtattggtgg tggaccagtc aatgtttctt tgttgatgct
    39541 gatgtttgca ttgccaataa aagaagcaac actatattct ctatctacga ttttcttttc
    39601 tcaactggca aaattggtaa cgattgcttt aacaagtagc tttatgcgct ttgatttatc
    39661 tatgttgttt tatgttatcc ccgctgctgt tattggaggt ttgtggggag caagatttag
    39721 cagggttttg tctccaaaaa aagtgacctt tatttttcaa gtaattgtcc tcgtggttct
    39781 tttggtcaat tgttacaatg cctttgtcat cttacaaaca ttaggagaat ctagactaac
    39841 gcaagtcaaa atcactgaaa catattgttc taaatgaaaa aaggagtata ctgtgataaa
    39901 aaaattcatt taaaaaaata aaaattggct ggtgatttgg atgttgcggg aaatgcgttt
    39961 aggagatgca gaagcactac gagaaatcaa tgcggaacaa ttaggatatg atgtaccatt
    40021 aaccgttacg gtgagacaaa tgaagaaact gttgaaggag ccagaaaaaa attttttctt
    40081 ggtctatgaa gatcctactt ctaaaaaagc agctggctat gtacaagcgg agtcctatga
    40141 atcgattttc agcgatccga tgttcaatat tatggcactt gctgtgtcta aacatgctga
    40201 aaaaagagga atcggaaagg ccttgatgac tggcgtagaa gaagcgaaaa gacgaggaat
    40261 atcagcaata agacttaatt ctgcagaata cagagtagaa gcacaccgat tttatgaacg
    40321 catcggttat cattccgata aaatgcaaaa aagatttttg aaaatcctgt aaatttttat
    40381 caaaaaatac ctggtcatca agccgatact tgatgatcag gtattttttt tgactaagaa
    40441 agtaattgca tcaagaaacc tgagatgatc aaaacgatgg caccaccaag ccgattgccc
    40501 atttgagcaa aagcaataag ttccatccga ttagctgcag ataagacagc tacatttcct
    40561 gtaccaccca tcgagttgtt gcataagcca gcagtaatag ttgattcgat tggatataaa
    40621 ccaaacaaac gaccgacaaa tcctgaaact actgaaatcg cgataacact tgtcaaacat
    40681 aagacaacaa attgccatgt caaagcagaa gccaatacat ttagattcaa taacgcaata
    40741 ccgataccgg caagaacagc tgctgtcaag tttttgacaa tcaagttgtt gaacatgata
    40801 gctgcatctt cgtaatattc tggtaatagg tttgcgattt tacagataac aacgataatg
    40861 atcatgaatg cgtaagcatg gactttagga acaaaatagt tacagatttg tcctaagatg
    40921 aagaaagtca atgataccat caaaccgaca cctaattgtg gaatggaagg ttttacattt
    40981 ctaggttttc catcgccaag gtcgcctttt tccattaatt taccattacc gttgaatttt
    41041 ggcattgatt gtcccgcacg agcaactaac gctgcaccaa tgatagctag gacatttgtc
    41101 attgctgtcg caggaatcag gcgggaaatg atagaagaag cgtccgtacc taaaacattt
    41161 gcataaatcg ttgataaagg tacagctccg gctccaacac caccagccat tgcgggcaat
    41221 gagatatata aaacggaatt tgcaaaacca tttccgataa gcatacctac gagtcctacg
    41281 gcaaaaaagg agacgaccat tgaaataagt gcaacgggaa taaaacgaac agaagctttc
    41341 atcaatagat tacggttcat accaaggatg ctaccagtaa tcaaggcagc aatataaaag
    41401 tctaaaaagc ccatattgct gacaaagttt tctgtggatt ttactacata ctcaggtaag
    41461 atcccaaatg tagcaatcgc ggcagaggca aagatcgcaa aaacggagcc accacctaaa
    41521 taacttttga cgatagggat ttttgttccg ataaaatgaa ataaattacc gaaaatgacc
    41581 aaaacagcga ttgggccaat catattcgtc ggtaattttc ctaaagccat tgcaatgatc
    41641 aggacaagga ccatgatcaa ataaaggggc aaacttacgc cggtaatttt tgttgaccaa
    41701 aacccttctt ttttcttttc ctcaactgca gttgcggttg ttgttttttg tgccattttt
    41761 acagatcctt tcttattctg tatcgtatga aaaaagccaa agagaagcgg caaaagagca
    41821 gtagttggct ggctgctgtt ttgccgcagt cgcttttttc tttttagacg tcatacaaag
    41881 tttctgtatg ttcttttact ataacaatct taatcttcta aagatttata ttcaggaacc
    41941 catttagcag attcaacagc ttctttgata tccgtgattt cttcacgatt caatttttgt
    42001 gcaacaactg attttgcgac agtttcagca atcgtttgag agaattcagt gatttttgct
    42061 actggaggca agatagctgc tcctggtttt gttacatcaa cgattccgcc taatgctcga
    42121 ctagcttgag aaatgatttc agcatttact cgtgtagctg ttgaagcaat caaaccaagc
    42181 cctaaacctg ggtacatcaa cgcattattt gcttgaccga tttggtaagt tacaccgtta
    42241 tattccacat cagcagcagg gatacctgtt ccaactaaag cttttccgtc cgtccattca
    42301 atcaaatctt ttgcttttgc ttctgccaat tttgttggat tagacaaagg catgatgatt
    42361 ggacgtgggg tatgagccgc catttctttc acgatttctt cagtgaatgc tccaggttgg
    42421 gtagaagtac cgatcatgat cgttggatgg attgctttta caactgcttc taagtttgtc
    42481 aattcatcag cattagtgaa ttctgagcgt ttacgagcga atgggatttg accaggagtc
    42541 aatccttttg tatcttcaaa caataaaccc tgtttatcta cttgatagaa atgttggcgt
    42601 gcttcttctt caggtacacc ttgacggatc atttcatcta aaaggatgtt tgcgatacct
    42661 acaccagcag taccagcacc aaatgtcaag atcgtttgat ctttcaattg ctcacctgat
    42721 atattcaatc cacctaatac accagctagt acaacgattc ctgtgccttg gatatcatca
    42781 ttgaaagtag tgattttatc ttcgtatttt tctaagatcg ttgcagcatt tcctcgtcca
    42841 aaatcttccc aatgtaataa caattctggg aataattcag tagctgattg aacgaattga
    42901 tcaatgaatt cgtagtaagt ttcgccttct acacgagcat gacgattccc taagtataat
    42961 ggattattca ataattcttc gttattagta ccagcgtcga ttgatacagg caagacttgt
    43021 gcaggattga taccagccgc agcagtgtag accatcaatt taccgatagc gatgtcaaca
    43081 ccgttcacac cccagtcacc catacctaag attccttctg catctgtcac aacgatcaaa
    43141 cgaatgtcgc gtccatctgc tgcgtttttc aaacttgctt tgatattttc tggttcgtcg
    43201 attgaaagaa atgcagcatc ttgtggtttc aagaaaattt cgttgtattg ttcgattgaa
    43261 tccgcaacga caggatcata aacgacaggc atgaattcaa ctaaatgttc gcccatcaat
    43321 ttataaaaca atgtccggtt cgtattgaat agattcatta agaagatacg tttttccaaa
    43381 tcggtctgtt tgcttaagta ttgaccgtaa gcttggacag attgttgttc caatgtttgg
    43441 acagtacttg gaagcatacc agtgattccg tattttgccc gttcttcttt tgtaaaagct
    43501 gttcctttat ttagaaaagg attatttaat aagtttagcc ctgtaagcat gaatgattcc
    43561 tcctaagttt taatacaaac gaagtatagg agtcagatga ggatatagtc aaaaagagca
    43621 ggtataataa attttattta tatgagtaat agagtcaaaa gaaatcaaaa tagcggtatt
    43681 tgttcttttt atatcaacaa tccttgcttg attactatgc gtatctctta tatgctaaag
    43741 aaagaaaagt agaagaataa aggatatgtt agatagataa atagaatctc tgaagaataa
    43801 atcacgtgat cgtgacgata aaatacactt acgtcaggtg ataaaaaata cataagtaga
    43861 aaactaagag gaggaacaga aaatgaaaga agttcaattg atcagaaaaa gcgaactatc
    43921 agaaggtggt tgcaatgcat gcggcgtagt agaagcaaca agctatacat taaagcttgg
    43981 tgccaacaaa gcgataatct ctgagttgac agtaggcggt cttgtggaca gtctggcgct
    44041 tgctgaaggt tttattggag aagatattta tgagatgttt tcagaaatcc gtcagttaaa
    44101 aaaaggggaa aactgcatag aggttcatca tgagagcccg aatgtgagat tcaaacgtgg
    44161 tgataatgag atgatcttca ataatcatgt gtccgatcac accgagctat atggaatcgt
    44221 gaatcaaata ctaactgagc tttttggatt gggaccttat gcgttcaagg aagaaaacgg
    44281 taatccaaaa ttaaacgaag aatggcaaga aacgattgaa atacaaagaa acaacccgca
    44341 cttatttcaa taggcatcca cagtatttcg taaaagggac tttgacacga cttttgtcaa
    44401 agtcccatcg ttttttatct atttgtgttc taaacatttc tttcagagta gtaacaactg
    44461 gaatgactga aatgtaaaca gattatttgc ctgtatcaat acggaagagt aatataaagt
    44521 gtgtaaacgc tatcatatta ttcattcaat tttttataga gggaaggcat tgaaatggaa
    44581 aaaacgtatc aagcaggtac aaatgaagga atagtggatt ttatcaatat ggaagattta
    44641 gaaatagccg cttcacaagt gattccagct ggtggttatg gttacatcag cagtggtgct
    44701 ggcgacttat ttacttatca agaaaatgaa cgggcattca atcatcagct gattattcct
    44761 catgtattaa aagatgtaga attacccgat acaactacac attttgacaa agaaacgctg
    44821 actgcaccaa tcatcatggc accagttgct gctcatggct tagctcatgt gaaggcggag
    44881 aaagcttctg caaaaggtgt agcagatttt gggacgatct atacagcaag ttcttacgct
    44941 tcttgtacat tagaagagat aagagaagca ggcggggaga aagcaccgca atggtttcaa
    45001 ttttatatga gcaaagatga tgggatcaat ttggatattc ttgaagtggc caagcgtaat
    45061 ggagcaaaag caatcgtatt gacagcggat gcaacagttg gcggaaaccg tgaaacagac
    45121 cgcagaaatg ggtttacctt cccactgcca atgccgatcg ttcaggctta tcaatcagga
    45181 gtaggccaaa cgatggatgc tgtgtacaaa tcttccaaac agaagcttag tccaaaagat
    45241 gtagaattta ttgctgctca ttctgatttg ccagtctatg tgaaaggtgt ccagtcagaa
    45301 gaagatgtct atcgttcatt agaatctggt gctggcggaa tctgggtatc taatcatggt
    45361 ggccgtcaac tagatggtgg tccagcagcg tttgattcgt tgcaatatgt ggcagaagca
    45421 gtagataaac gtgtaccaat cgtgtttgac agcggtgtac gacgcggaca gcatgttttc
    45481 aaagcaatcg catcaggtgc agatcttgtt gctattggca gacccgttat ttatggattg
    45541 tctttaggag gaagtacagg agtccatcaa gtgtttgatt tctttaaaac agaattggaa
    45601 atggtcatgc aattagctgg aacacaaaca gtagaagata tcaaaaaaat aaaattgcgt
    45661 gagaatcgtt ttatttaaga aacaaatgac gaaaaaaata ggagtgcggc agatgatgcc
    45721 gtactcctat ttttatagtt caaggatgtc actaatagaa taatttgaaa cgaaaaaata
    45781 aaattgaaat attttttcat acttaataaa aaaggaagaa tattcatgta aacgatttta
    45841 ttgttttttt ctcttttata caaaaagggt cataatttca agtaagcgga tgaattcatg
    45901 aggatttttt gcatactgtc tctactatac ttaggtcact aagaaaaagg agtgatttat
    45961 tatgaaaaag aacatgattg ggacattatt actttcaaca cttcttctag gcggcttggc
    46021 aacaccagct tttgctgagg gtcaagcgac ttcaaaagga gatattacct ttactgaacc
    46081 aacaaatacc gtggagcctc ttaaccctac tgatccttca aaaccagtag agccagcaga
    46141 tccggaaaat ccagcaactg gccagacagg tcctttaaca ctggatgtag ttcccgaatt
    46201 gccatttggt acacacgaga ttgaaagcgg aacaaaaacg tatcaagtag acgcttcaaa
    46261 aaacgataca ccttatctcc aagtatcaga tcgtcgaggt gtaggtgcag atggccaagc
    46321 acaagggtgg aacgtgacag tttcggtttc agattttgta aacggttcac aagttttgca
    46381 aggcgctgaa ttagattttg gaacatccac tgttaaaagt acgtcagata acgaatccac
    46441 tggaccaact agtcaaactg taactgggtt gagtaaagca agtgcagcga caccaatatt
    46501 tacagcagca aaagatcaag gtctgggaac atggctttct gtttatgatc cagcaaatat
    46561 cacactgaaa gtgccgaaag cagcagctgg aacattcacg gctgatttga cttggaacct
    46621 cgtggctggc ccagtagcat agagtatgaa ataaattcaa caaactgcgg tgaaaatact
    46681 ataggtgaag gattttttac cgcagttttt gttgaaagga tgtggtggac aatgaatcaa
    46741 agtaaacgac tgtttgtttc gtttttttct attttaagtc tatttttcat ttttccgtca
    46801 atcagccaag caaaggattc agcaggagac tttggaatca aaccggtatt tccagagaac
    46861 caaatagata aagcaatcgg ttattttgat ttattagtgg caccggaaca aaatcagaca
    46921 ctagaagtaa ttatcagcaa ttcttcagat gaagaacgaa catttgaggt ctctgtcaat
    46981 ccggcggtaa cgagtgatgg tggaacgatc gattatagtc aaaaaaaccc aacgttagat
    47041 gagacattgc cgtttgatgt ccgtgacgtt ttgctcattg cgaaaaagga aatcaatgta
    47101 tcagcacatg cagaaacaac tgtacctata gaagtgaaaa tcccagcaaa aagctttaag
    47161 ggacgtgtat tagcgggtat tcatgtttca cctaaagaag aagctgaaac agaaaatgct
    47221 acagaaggag cacaaatcaa aaatcgtatt gcttataatc tcgcagtcgt tttacaagaa
    47281 agtcaagaga cgatagaacc ggatctgaaa cttttatcag gagatttgga cgaggtcaac
    47341 gcaaagccaa ctgttcagct tcgtttccaa aatcctcagc ctaggattat cagcaatttg
    47401 atatttacga gcaagatctt ttatgaaaat cagctttata ttgaaaatac gtctaatgca
    47461 tttttagttg caccaaattc gaattttcac ttgaatcttg atttagctgg tgataaagca
    47521 aaagccggcg attaccgcgc agaaatcata gcaaaatcag gcgacagtaa tgaatggcga
    47581 tttacacaaa actttacgat caaaaaagaa aaagcacaaa aagtaaatga aaattccgtt
    47641 tttgcagtac aagaacaatc tttcccatgg ctttatgcag gattggttgc tgcagttcta
    47701 gtgttatggt tgattttgct gtttttgtgg gtccacaaga aaaagaaaaa aggagaaaca
    47761 acatgatgag gtgatttcgt tgaaaacatc gatcttattg ggagggatta ttgcaagttt
    47821 gctgttcttc agctggcaag agccagtcca agcagatacc aaaagttcag gtacgattac
    47881 attttatgat ctaagtccaa ttccgcatcc aagtggttca gtcaatggcg catcaaaaca
    47941 gcagacacag ctaccgattt ataaagaatc taatcaacat ggcgtattcc cggagacgaa
    48001 tgaacaaaag atccgttttc tttatttgat cattggtata gaattatggc ttcttgcgtg
    48061 gttgttgtta tggagaagaa aggaaaagga ggatgaacat gttgctacaa aataaatttt
    48121 cattttttcg ctccttcttt tttacttcgc tttttgtttt aagtatattt atcttttcac
    48181 cttcggcaga agctgttgga gcaacgcctc ctgccatttc ttatgatcca tacacgtatg
    48241 aaaatatcgt acctccaaat ggtggacgta gtgcagtcaa tggcgggaag cttgtccaac
    48301 taactggggc taaccaattg cctaaattga ctgctactta tttgaacgat ggttcaaatg
    48361 atccttggaa aggtggcacg gtccgttttc attgggaaag ccatgtgaaa ctaacaaatg
    48421 tacttgattt ggtgaatatc actgcacaag gatttgcatt tgtggcgatc atcaatttgc
    48481 cggaacatgt atcaagcagt gatgtattaa aagcaattga ctggaacaac gcctacttgt
    48541 atattgccgg tgcccccatc aaggttacta gcggaagttt attatcagca ggaagccata
    48601 ccttgcgttt tgggatgggg tcgtgggata caaatactct attgacagat attattgcta
    48661 ttattacgcg aggcgaattc aacgtggacg atatcccgct tcaatttgat gttacagcta
    48721 atgtcgcgaa gatgacagaa aacggagata aatatgatac gagtccaaac aaaattttga
    48781 ccaagggtaa attacaacct tctatgtcta aaaaggccgt tttttctgtt gatttttatg
    48841 attcgaataa tattatccaa gatcgtatgt tcaattcgat tttagctcca gctgcaggta
    48901 gattttatcc taaattaact ggcggaaact tgaatccagg agcatatgca ttttctgcaa
    48961 gtgcagagat aaatacgtgg aatagttaca tctcaccaag tgattcaaca ggaaaatata
    49021 atacatttgc tgataccaca gaatacgtgg atggaaataa ccagaacctt ccaggctcta
    49081 ccaatagtcg gacattgacg atggggctga ctgaaggacg ttttgatcag ttgccattta
    49141 gtcgctttga tcgcgtagtc aactatttta caggaaaaaa cgttacacaa ggagcaatac
    49201 tgactcatac tccagcaagc acaagtggat tgaatcagac agccaatatc gtgtacagtg
    49261 ggaaagatgc gcaaggcgga ttgctttctc ctgttgcttt aaaggtattg gagcagtaca
    49321 agctagacgg aacggtttta ccaacaaact taacagccga tagtcagtgg ggaaagctcc
    49381 tttcttctgc atcgtaccaa gtcacggcca attggtcagc aactgaacta aaaaagggtt
    49441 cgatccatta caggctttat tcgaaaggaa cccaaaaatt agcgacagga tggacagatc
    49501 aacttttcca aacgatccaa tcaaataacg ggggtgtaaa tacagctact tctacactac
    49561 ctgcattggc ttcagggcaa tattattttg attatcgctt ggtggacgat gtacttacta
    49621 acatgtatcc gtcttttgcg tacaaatggc agtctgaaca agctggaatc accactcttc
    49681 ctcaaataac agtggctaat tttccatctg tgagtgcaga tagtcagcta aaaaacctta
    49741 gcagacaacc tgagacagga gatcccctgt ctgctctatc aggagatacg attcaagaaa
    49801 atgtgacatt cacgttaaca aaatctgggg atgcgataac cgacaaaaaa atcacgatct
    49861 cacttcctga aaatactact tatatcaatg gttccttaaa attaaatggt acaactatcg
    49921 cagataccgg cattcaacaa ggagtttctg tcccagcaga tctattgagc aaaataggag
    49981 ataccattca tcttacttac aactatcaat taaatactgt agatacttct ttacaatccg
    50041 tcagcatact gacaaaggca gctgtacttt ccagcaatat tacattagca gatggtgcta
    50101 agcttcctaa cccagttgtc caaacatctg ctaaaacaat tcttgtcccc aaacaagaat
    50161 taacattagt taatgtacca gatgatttta catttggtaa cgatctcccc aaaccgttga
    50221 agacaagtta ttatgaatca aaaggcgatt tttcttttga tgtgcgggat actcggcttc
    50281 caagcacgtc tccttggcaa ctgacaggta cattgacttc tttatttaag aatgatcaag
    50341 gtcaagaatt aagcggaaca aaattatact tcaatcattc tggatcaaag caattgattc
    50401 agcaaggtca aaacacgttg atttatgaga gtgatggaac agctaaagga gaggttctcg
    50461 ttgactttcc cgataccgat ggtttactct tagaggtaaa tagcagtacg aatgctcaac
    50521 ctggcgcaac gtatcaaggc atggtcacat ggaaactgac agctgggcca accagctaag
    50581 tgattagaat ttgtatggat ctgtgataac tgtcacagat cctctttttc aaggatgaga
    50641 aggaaacttc tgctgttaaa atcagaaatg cttgaaggag tggacttgga acttttcagt
    50701 ttgcttgaaa aaaatgaaca acggcaaatc aaacttttcc aacttttatt agaggaaaaa
    50761 ggagaggttt ccgttaataa cgtacttacc cgcttatcag ttgatcgggc taccttgaaa
    50821 gaagatctgt tttatttaca agctaacttg gaaaatatca aacaattgga aattgttatc
    50881 caagaaggga atattttatt aatcagacat ggaaatatag cagcagtcga tgtttattat
    50941 cattgttact tgcgctattc tacaaaatat cagatacttc tttatctgtt ggaaaatggc
    51001 tcatttgatc ggcagaaact tgtcatggaa cttaatatca gttcggctac tttgtctcgc
    51061 agagtgaagg aattaaatga ttctttaaat gagtttcatc tgaaaataaa aagcgggcgg
    51121 ctgaccggtc cagaaagtca aattcgttat ttttatttcc aattattttg gtttggacgt
    51181 ccctatcttg aaaacaaaaa agaatacagt gatttatcag gaaacacttt tttagatctg
    51241 ctgcaaaaag agtttagttt tgctattaca gaagaaggac gattgaaatt tgaaatatgg
    51301 ctttccatta tgaagaagcg aatgcgctgt acgaaaaaat ccaaaccaga ttatagcaat
    51361 cttcctgttg gattgtttca aacgacacaa tttttattgg acctccatac atttttgacc
    51421 cgttacttct ttcaatatgc ctttccttgg aatcaaaatg aaacgttggt tttttatctt
    51481 ttcatgatca gtaactttac attagataca cataactcgc atgtccagga gtttttgata
    51541 agcgaaaaat acaaagacga cgtagtagct caattgaatc gaacgtttaa acaatcgata
    51601 gaagaatatt tctcttttta tgtttttcca gaagagattt cgcaaaagat tgcgttgaca
    51661 gtgatgcaaa atcacgctca ttttgcctat tttagaggat ggatgaatat ttttggccaa
    51721 gaaggattaa aacagcggtt aactgaagta gaagataaac aattcctggt tttatgtgaa
    51781 agattggtca gacaaacatt tgctattgtt gattttactg aagtagacga ggaaaatgcc
    51841 cgctttgaat tatttgctcg ctatgcatct attttacgga cgctgatcaa gcagttagaa
    51901 ttacgtctgc aaattgctta tgatcttcct tatgaaaggc taatggcgga tatcgtgaaa
    51961 gaaatcatcc aggaacaatt gctgaatacg atcaaatatg atttagtcga atacgagaaa
    52021 gaaaagcagt atgatatcat tttgactagc caattgaaag agtacccgtc acagaagtcc
    52081 gctaaagttt ttgtattcac tagcaacgaa tataattatg atttccccta tttgaaccaa
    52141 tttttaaaag aatgttattt agaaaaattg aatttaagga tgaataaaac atgaaaatcg
    52201 tgatcattgg tgcttcccat gcaggcatca cagctgccct aaatctaaga aaacttcaac
    52261 cgaaagcaga agttttactg atcgatgaag atcataaaga tggactaggc tatgtttcaa
    52321 atggaatcaa cctttattta aaaggaaaga tacgtagttt agctgaagtt gcccataaca
    52381 tgcggactct tcaagaaagt ggggcaaaac tgatcaccga atggagagta actgaacttg
    52441 atccagacaa acatcagctc atcctcgcat ccaaagaagg aaaaaacgag accataacct
    52501 atgataaatt aatcgtagcg acaggttcct ctcctgtcac cttgtataaa caaattgaag
    52561 ctgaaaatgt ctacacctat aaaaatctag tgcaatctaa gcaagtactt gccgctttaa
    52621 aagaagcaaa agaagtagtg atcttcggtg ctggttacat tggattggaa ttagcagatg
    52681 ctttgagaaa taaaggatac attattcatc tagttgatta tatgccgaat gttttatcaa
    52741 gatatttcga taaggatatg atcaacagtt ttcaaaatca gctgcaaact aagcaaataa
    52801 atttttatcc aaatgaattc ttgatcgatt ggaaaaaatc agaagagaaa gtagtatccg
    52861 tacaacttct gtctcaaaca ataaaggcag atatggtcat tttttctgcc caaactcgtc
    52921 ctaatacgac attgttaaaa gaaaaagtgg ctttgtatga ggatgagact gtgatagtca
    52981 atgaatatct gcagacaagt gatccggaca tctatgcgat tggagatatc gtcccagtca
    53041 gttttgacaa aaataaacgg catctctttt tacctttagt tactcgagct gtacatatgg
    53101 caagagcagt agcgctaact ttgagtggtc agccaaccgc ttacgacctc agacaaaaga
    53161 taacagcagc agtcattata gactactttt taggaactgt agggctgaca gaagatgaag
    53221 cgccattctt ggaacaaaat accggttcgt gttcaggaga atttgatcta tttccacaat
    53281 acgacgaaga aaacaaaaca gtaaatgcaa agctgatcta ccatccggat acattagaaa
    53341 taattggcgg acagctgata agccaagaat tcttattatc agatttgaac ctgcttgcgg
    53401 atatcgtgaa acacaaaact acgattccac agctagcagt tgaggatttt ggatttctgt
    53461 ctgaatacac ctctcgtttt cactacctca atgagttagc ttttaaagta ctagctaaga
    53521 gagcaaatag caatagagta gataaaagac tgtgagaaat atcacggtct tttattgtgt
    53581 ggggatataa taaatattaa tcaatcgaga ataaaaaatt catataatga aatagcggaa
    53641 gaattttttg agcataatat tcgccaaaaa tttatcaagt gataaaattg ttgtataaaa
    53701 tgattatttc aggaggagga gttaaatgtt tttagcatta aatgaaatta tgcattcaaa
    53761 gttacgttat gcgttagttg caggggtgat gtttttgatc gcctacctgg tatttttttt
    53821 gactgggtta gcttatggct tagctcaaga taatcgaaca gcagtcgaca agtgggaggc
    53881 agattcgatt gtgctttcga aagatgcaaa ttcaaatcta gggatgtcca tgattactaa
    53941 gaagatagca gaagaagtcg aaggtgggaa agtggcgtat cttgcccaaa cacctggagt
    54001 cgtgactagt aaagacagta cagaagaagg aaaaatcaat gttagcttct tcggtatcga
    54061 taaaaatcaa ttcatcatgc ccaatcttgt tgaaggaaaa gcttttgata acgatgatga
    54121 ggcagtaggc gatattagtt tgaaagaaga atatggtcta gccataggag atacagttaa
    54181 gttatctggt agtgacaaga cgtttaaact aactggcttt acggatcatg ccaaattcaa
    54241 tgtctcacca gttctctata caaccatcaa tgcttaccaa gaaatccgct tcgaaaaaga
    54301 agatacaagt gaaaatgcac ggattaacgc aatagttgtc agaggtaaaa tcagtaattt
    54361 acctgaagat ttagaacaga tcaaaatttc taaattcatc aatgaattac ctggatataa
    54421 tgcgcaagta ttgacttttg gatttatgat cggatttttg atcgttattg cggctattgt
    54481 gatcgggatt ttcatttatg tactgacgat gcaaaagatt aatatctttg gtgtaatgaa
    54541 agcacaaggg atcacaggag gatttattgc gcgttctgta gtggcacaaa cattcatttt
    54601 atcatttgtt ggtattcttc ttggtctatt aggaacagtg ggaacatccc ttgttctacc
    54661 tgatgcggtt ccattccaaa gcaattggct gttttttggc gtcattagct tgttgatgtt
    54721 agtagtagct gtgttaggcg cactattttc tgttcggaca atcgtaaaaa tcgatccgtt
    54781 gaaggcaatt ggataagaag gaggaagaac atgaaagcaa tagaatttaa agaagtagaa
    54841 aaaagtttcc aagatggcga ccaagtagtt aaagcattga aagaaacaac catgagtatc
    54901 gataaagggg aatttgttgc aatcatcggt ccttctggtt caggtaaaag tacttttttg
    54961 actttggcag gcggattgca gacgcctagc agtggctctg tatttatcaa tgatcaagaa
    55021 ttcagtaatc aaaaagaaag cgaacgcgtt aaactacgtt ttaaagaaat tggctttatt
    55081 ttgcaagctt ccaatctggt tccttttctg acagtaaaaa agcagttatt attagtagat
    55141 aagattaaac atgaacatcg tcaaaaagaa gcaaacgaat tatttgagca gcttggcgtg
    55201 gataagttga tcaacaagta tccagaagaa ctatctggtg gagaacggca aagggtcgca
    55261 atcgctcgtg cattgtacaa tgatccgtcc attattctag cagatgaacc aactgctagt
    55321 ttggattcag aaaaggcacg agaagtagtc gatatcttgg caaaagaatc aaaagacaaa
    55381 aataaagcaa cgatcatggt tactcacgat acacggctga ttgacaaatg cgatagaata
    55441 tttatgatgg aagatggtgt attgaaagaa aaagaataac caaaaagcag gtggaaaaat
    55501 ggtccatcga tacaacaaag atacacagca aaaaattttg aaagaagcga ctgacttgtt
    55561 tatgtccaag ggatatctcg gcacttcaac aagagaaatc gcacaaaaag ttgggatcac
    55621 ccagcccaat ctctatcatt atttcggtga taaagaaaaa ctatatacgg cagttttaga
    55681 aaaccactta aaagatgttg gaaaagcttt gagagaaatc gttcaaacaa gcgaaacggg
    55741 atttcaagta accttgacaa aaatggcgca gtttttgatt gagacacatc tggtcgattt
    55801 gtttctgatg cttcacgatc ttgaaagcaa tctttcaaag gaaacaagag atcatctttt
    55861 ctttctatgg aagaaaaatt atcgtgaacc ttttgaagaa atcttttcag caaaccaatc
    55921 tgtgctaaga aatgggattt caaaagaaat cgcagcaagg cattttttct tagtgttagc
    55981 accttacatc actcggtcga aaagacctgt ggaagaaccg ctaaatgtgg cgcaattgat
    56041 cgatttatat ttgaatggtg tattaggaga agcgtaaagc tgttatatag ggagaaaata
    56101 gttaggtgaa gaagcaagat atgacgaaga tcgttatatc ttgcttcttt atataggtag
    56161 tttttcataa agacaaattt gttattctct catgattatc agggtatatt tttatttatt
    56221 atgtcggtgt tccaggaagt gttttaattt aataacgaag aaattaattg tttgtagaat
    56281 gaaggaaact atttattggg tagatgaatc accacgaata gtcaaaagga gatttcagga
    56341 tatgccaaaa atgaaaaaaa tcattttagc agtaatgtta ttttctacgg ttatatcttt
    56401 tacagcccct tttttgctta cttaagctga ttttaagttt tggcccttag tctggatcta
    56461 cgaggtgaga gtcaagaatg aaaaaaataa ttggagcttt tgtatttgca atcattatca
    56521 ttattatctg ttttcaaata gatgtttttg gtcaaaaaaa gatagttgga caaacggtca
    56581 gcagtacgaa cagtacggtt acaaagacaa aggaatcatt tgatgataca gaacaagaga
    56641 cattaatcaa aatcggaaaa aatgaccgta cactatatac agatgactcg ctaactaccc
    56701 cacttgcaac tataaacggc ggagagctgg cggagtttct ttctgaaaca aaaaatgctt
    56761 atcagatcaa gacaaatgat ggctatactg gatatttagc cctcgaagat ggaaccaaag
    56821 tcacaaagaa tatacaaaca aaaccggaag agctatctga tgcagtgatt gtattagatc
    56881 ctgggcatgg cggaaatgat actggggcat taagcaatga tgaacaaaca gaagaaaaag
    56941 atataacatt aagtacagcc ataaaagtaa aaaaggcgct agaggatgct ggagcaacgg
    57001 tttatttgac ccatactaca gatgaattag tacagcttgg agatatatgc gactacagtg
    57061 aagaaaaaaa ggcagatgtc tttatcagtt tacacgcaga ctctacggaa tatgcgaatg
    57121 aagcaactgg aatcacgaca tattattact atggacaaga ggaaacatta gcacagacaa
    57181 ttgctgactc cttcactgat ctgcctctgg attcaagagg aatctccact gggaactatc
    57241 aagttcttcg agaaaatctt caaccttcta ttttaatcga gatgggttat atgaataatg
    57301 atagtgattt aaaggaatta gtaacagaca gttatcagca gcagattgct gcaagtttga
    57361 cacaagcatt gaccacttat tttcagtaat aaataagccc agccaaacaa aaatagctcc
    57421 tcatattttt cgtttggccg ggcttattat cgcagatgca agcttttgaa caccgtttat
    57481 ttttttagta gcttcaaagc tttttctgta tttgcaaagt gaagtttggc atatttttca
    57541 agcataggca tgccgccttt ctccaatagt tttgccgcta cttggtcaga tttcgttcca
    57601 gctcctgatg gaagggtgat tccagcttca gctgatgctt tgtgtaactc ttccaaaaag
    57661 ctggcacgac tgatgataga agcagcagca acagctaaat gatattgttc tcctttagta
    57721 acgaagtaca gtttttcttg taattgattt ttttctaaac gcgcatattt tttaaaattt
    57781 gcttccggcg taaactgatc gatcaaaatc gcttctggtt tttctggctc gatttttttt
    57841 agcagcaaat ggatcgcttg attgtgcaaa gcgactttca tccgaacggc attgtatttt
    57901 ggttggatct cattgtattt ttctggagat aagacaagca gtttataggg gatggttttt
    57961 tttaagatgt cagcaagctg gatgatttgg ctatctttta actcttttga atctctaaca
    58021 ccaagtttac gtaattctgc aagctgatca cgtttcacat aagcagcaca tactgttagc
    58081 ggaccgaaat agctgccatt tccgacctca tcactaccta aaacggataa ttgactgata
    58141 ttttttggca aagaagaggc tgtttttgct ggcttggctt gtttatcctg tgcctccccc
    58201 catttatcag cttctattgc tgcattcgta ccttgaaaca tcacttttcc ggatgtataa
    58261 gcggtaatgg tcgtcccgtc tttttttgca gcaaagctag tataaggaat ctgtttattt
    58321 aacaaataag agcgatagta tgctttcatt tgactaagtt ggtcgtttgt tgctttgata
    58381 atgacgttgc tcataaaatt ctcctcgttt ttatacataa aactataccg caactcacga
    58441 cttttcgttt tctaagagat tgcgagacat agcatttttt taaagtttat catataatag
    58501 ttaagtatgt gaaaaatatt tgtggagaac ggtgaaagaa ccaacttcat ggtacactaa
    58561 ataaaacttt catcaaatag gaggaaatga ttcgtatggc gcacgaaaaa acacgctaca
    58621 aagcggtgat tgccaaccaa acatatacta ttatcggacg ggaaaccaag catcatatgg
    58681 atatcgtaac gaagctgatc aatgaacagt tagcagaatt gaaacaatta tcaccacaaa
    58741 tggataatga acaagcagca atcttgatgg ctgtcaatgc gctttcggat caattgaaga
    58801 aacaagaaag aatcttggag ctggaagaag aaacagcaga attaaagaaa aaaatgatca
    58861 aatttacaga gcttgaaaat cgtgtgaaac gcattgaagc aatcgagaac gaagctcggg
    58921 aagtattgaa agaaaatggt caagcagatc ataccattaa aaatcatgtg gaagcacaac
    58981 agattttaaa cgagaaacga aaaggacaaa ttaaacaaaa atcttctaat taagatcctt
    59041 ttatcaaaat aagaaaaatt taaaaaaagt tagaagagaa aggaacgtag catgctgagt
    59101 ttgctgattt tatttttatt gctaattgcg tttttttctg gagcacgtcg cgggtttgct
    59161 ttgcaaatca tattcgcgat tggatatgta ttgtcattta ttgctgccca gcatttttac
    59221 aaaccattag caagtcattt ggaattatac attccatacc cagctgtcac gccaacatca
    59281 aagttagcat tttttgatca ggtatttgcc tttcacctag atgaagcttt ttatgcagga
    59341 actgcttttc tgattatttt gctaattggc tggctgctta cccgatttgt gggggttttt
    59401 gtccatggat tgacgtatgt gccgatcttg agacaggtag actggattgc aggaggcatc
    59461 ctgtcactaa tcatggctta cgttactata tttttgattt tgcagttact tgcctttgtt
    59521 ccattagatg tggtccaaaa tcaattcggc gagcatagtt tcgctcgctt tatcgttgag
    59581 agaacgccat ttcttaccaa caagatgtat gagctttggg taacgaatat tttgaattaa
    59641 ggaaaatagt gctggaaaat atttcgtttt ttgtacagag tagattattt aagaaggctg
    59701 cgtagcgtat gtccggcaca gctctttttt catagtgaaa gataaggtga taaaatgaat
    59761 aaccgaatcc ttgaaacatt ggaatttgaa aaagtcaaac agatggtcag acaatttgta
    59821 gtgactgcac aaggaaaaga agaactggca gaattggtac cagtgagcga ggaacaaacg
    59881 atcacaaact ggcttcaaga aactgaggat ggattgaaag tgcaacgtct gcgaggcggg
    59941 atccctatac ctaaacttga aaatatccgt ccccatatga aacggattga gatcggagca
    60001 gacttgaatg gagtggagct tgcacaagtt tccagagtat tgtctacgac aagcgaattg
    60061 aatcgtttca ttgatgatct ttatgacagt gaaatcgaat ttgcacgttt gtatatgtgg
    60121 gcagatcagt tagtcacgat ccctgttttg agccgccgtt taaaggaagc aatcgatgaa
    60181 gacggacgcg tgactgatga cgcttctcct gagttaaaga gcataagaca gaacattcgg
    60241 cgaagtgaac aagctgttcg tgaacagtta gatgggatcg tccgtgggaa aaatgcaaag
    60301 tatttaagtg atgcgatcat caccatgcga aatgaccgct acgttatccc agtcaaacaa
    60361 gaataccgcg gtgtatttgg cggtgtagtc cacgatcaaa gtgcttcagg acagacttta
    60421 tttattgaac caaaacaagt ggtggatttg aataatcgtt tgcgtcaata ccaaatcgct
    60481 gaacgaaatg agattcaacg tattttaagt gaactttctg ctgaacttgt tccccatcgt
    60541 caagaaatca tccacaatgc ttatgtgatt ggtaaaatgg atctgatgaa tgcaaaagca
    60601 cgatttggta aagaagtaaa agctatcgtg ccgggaatca gtgaagacaa tcatgtcgtc
    60661 ttgaaacaag caagacatcc actgatcgat caggaaaaag tagtttctaa tgacatcaca
    60721 atcggaaaag actatcaagc catcgtcatt acaggaccta acacaggtgg gaaaacgatc
    60781 acgttgaaga ctttaggtct gttacaactg atggggcaag caggattacc gattcctgca
    60841 ggtgaagaaa gtcaaatcgg tatttttgag gaagtatttg cggatatagg agacgaacag
    60901 tcgattgagc aaagtctatc gaccttttct tctcatatga cgaacactgt agatatttta
    60961 tcaaaagtca atgaaaaaag tctggtatta tttgacgagc tcggtgcagg aacagatccg
    61021 caagaaggtg ctgctctagc aatcgcaatc ttagatgatc ttggtaaaaa gtctgcttat
    61081 gtgatggcaa caacgcatta tcctgaattg aaagtttatg gatataatcg ggcaaatacg
    61141 attaatgcca gcatggagtt tgatgtggat acattaagtc caacgtatcg tttgctgatt
    61201 ggcgttcctg gacgaagcaa tgcgtttgaa atctctagcc gattaggtct tgatacagaa
    61261 gttattgatg aagcgaagca gttgatgaat gatgagagcc aagatttaaa cgaaatgatc
    61321 acagatttag agaatcgccg gaaaatggca gagaccgaat atctggaaat gcgtcatttt
    61381 gtttctgagg cacaagaact tcacgatgat ttgaaagaag cttacagcta tttctttgaa
    61441 gaacgtgaaa aagaaatgga aaaagcaaag aaaaaagcaa atgaagtcgt gtcagaggcg
    61501 gaagaaaaag cagaaaaaat cattgctgat attcgtaaaa tgcaacagca gattgggcaa
    61561 ggaaatgtga aagagcatca gttgatcgat gcaaagaccc aattagcaaa tctacatcaa
    61621 gaagaaactt tgaagaaaaa taaagtattg aagaaggcga aagaacaaaa aacgttgaaa
    61681 ccgggagacg aagtgttggt tacgacttac ggccaaagag ggacgctttt acgtaaaaac
    61741 gggaatcagt ggcaagtaga aatcggtata ttaaaaatga atgtgtccga agacgagctg
    61801 acgcctgttg ctcctcaaaa agagccgaca caacgagtta tccatgctgt acgatctgaa
    61861 tctagtagtc acgtgccgaa tcaattggac cttcgaggaa aacgatacga agaagcgcta
    61921 agtgaggtag atcaatattt ggattctgcc attctagctg gttatcctca agtgactatt
    61981 gtccacggaa aaggaacagg cgcacttcgc aagggaatta ctgattatct taaaaaccat
    62041 cggagcgtca aaagctttga gtttgcaccg gcaaaccaag gcggaaatgg tgcgacaatt
    62101 gttaaattta agtaaagctt actaaaggta agcagatggt tcgctatcca agtatagaaa
    62161 tgctatacta gtcatagatt ttaaaaatgg aggtctttga tatgtcacaa gtaattacag
    62221 ataagacatt taatgaagaa acagataaag gacttgtatt gattgatttt tgggcaactt
    62281 ggtgtggtcc atgtcgtatg caagcaccga ttttggatca gttggaacaa gaatatgatg
    62341 aagaagaatt cagaattgct aaaatggatg tggatgaaaa tccagaaact cctcaacaat
    62401 tcggtatcat gagcattcca acattaatgt tgaaaaaaga tggtcaagta gtagaaaaag
    62461 ctgttggtgt tcattcaaaa gaacaactac gtcaaatgat cgatcaatat ttataaaaac
    62521 ttacagcaaa aataagctga gggtgggact gaatccagtt ccgtcctcgg tttttttgcg
    62581 gttgagttaa ggttattcaa attaatattt tttgagtata attacgttgt caggctggat
    62641 tgtttttttg acagacatgc tataataact ttaattgaat atgaagggga gtaccagatg
    62701 aacgaacgaa tcaaaaacaa attagcttta cttcctgatc agcccggctg ttacttgatg
    62761 aaagataaaa atggaacgat catttatgtc ggcaaagcca aaatattaaa aaatcgtgtc
    62821 cgctcatatt ttactggtag ccataatacg aaaacggaac ggcttgttag tgaaatcgaa
    62881 gactttgaat acatcgttac agaatcgaat atcgaagcat tgctcttaga gatcaatctg
    62941 ataaagaaaa atgatcctaa atacaacatt atgttaaagg atgataaaac ctatcctttc
    63001 cttaagataa cgaatgaaaa atatccccgt ttggtgatta ctcgtaaggt actaaaagac
    63061 aaagcactgt attttggacc atatcccgat gtcggtgcgg cgaatgagac aaagaagatc
    63121 ctcgatcgat tatttcctct gagaaaatgc aaacctagtc agacgaagga gccttgtctt
    63181 tactatcatt tgggacaatg tctgtgtcct tattatttcg acgtagatcc gaaagtctat
    63241 acgaaaatcg ttgatgaagt gaaaaacttt ttaaacggag gacacgaaaa aatcgagtca
    63301 gagatccatc agaaaatgga aaaagctgct gaaaacatgg agtttgaaaa agctgcagaa
    63361 taccgagacc agatccgtgc cattgagaca atcatgactc gccaaaaaat gacaaatact
    63421 gatttactgg atcgagatgt atttggttat gcgattgata aaggatggat gtgtgtccaa
    63481 gtgtttttcg taagacaagg aaagctaatt gaacgagatg tttcaatgtt tcctttctat
    63541 aacgaagcag aagaagattt cttgacttac ctcggtcagt tttatcagga aaatgagcat
    63601 ttcattccta aagaagtctt gattcctgat acgatcgaca agcccagtgt agaagctttg
    63661 ttagctacga aagtgctgca accaaaacga ggagaaaaga aaaaattagt tgaattggcg
    63721 agtaagaatg cctcagttgc tttgaatgaa cggtttgatc tgattgccag aaaacaggaa
    63781 cggacgatcg gagcagttga acgtttagga aacgcgatga atatcccgac cccaatacgt
    63841 atcgagtctt ttgataactc taatatcatg gggacgaatc ctgtggctgc gatggtcgta
    63901 ttcattgatg gaaaaccggc aagaaaagaa tatcggaaat ataaaataaa aacagtcaac
    63961 ggaccggatg attatgcatc aatgagagaa gtcatctatc gcagatattc gcgagtgatt
    64021 cgcgaagggt tgcctttacc tgatttgatc ttgatcgatg gaggaaaagg acaagtagat
    64081 gtggcaaaag atgtcttaga aaatcaatta ggaatcgata ttcctattgc tggcatggca
    64141 aaaaacgata aacataaaac aaatgagttg ctattcggta cagatttggc tgtagtaccg
    64201 cttgagcgaa attcaccaga gtttttctta ctccagcgaa tccaagatga agtccatcga
    64261 ttcgcaatca ctttccatcg gcagctacgc agtaaaaaca gttttgcttc ccgattagat
    64321 gaaattgaag ggttaggacc aaaacgaaaa aaaatgctgc ttaaagagtt caaatcgttg
    64381 aaaaatatca cagcagccac gacagaagaa ttacaagaaa tcggactgcc gaaaaatgtc
    64441 gcacaaaacg tatttgataa attacatcag gaatgaggaa agggcacttt acaaagaaag
    64501 taaagtgtcc tatcatttta tgtacaacaa aaagagcgtt tacgttttgt tggtaaataa
    64561 taaatcgctt acgtctggtg tctaaggata tatgtgattt cttgaagaag gagtgaagaa
    64621 atgttagaag tcaaggatct tgttaaaact tttgggaact acacagctgt cgatcatgtc
    64681 tctttccaaa tccccgatgg aaaaatcatg gggctaattg gccaaaacgg ggctgggaag
    64741 acaacgactt ttcgtttgat cttggatttt ttgacacaag accaaggaga agtgttatgg
    64801 aatggccatc atcttgggga gaaagattat gatgtcatcg gttatcttcc ggaggaacgg
    64861 ggactttatc cgaaagtaac gattcaagac caactgcttt attttgcaga acttagaggg
    64921 aaatcaagaa aagagattga accaaaaatc gacttttgga tggaaaaatt tcaggtaaaa
    64981 gggaaaaaga cggataaagt aaaatctttg tctaaaggaa atcagcaaaa agtccagctg
    65041 atcgccacgt taatccatga acctaaattg atcattttgg atgagccatt cagcgggtta
    65101 gatccggtaa atgctgaatt gctaaaagat ggaatattgg aattgaaaaa acatggttca
    65161 tgtgtcattt tttctagcca caatatggat aatgtagaaa aaatctgcga tcatttgatc
    65221 atgttgcgaa acggaaaaat ggttttgaat ggaaaagtac atgagattcg tgaatcattt
    65281 ggccgtacga agttattctt ggaatctggt ttaagccaac aggaagtaga agaaatcgaa
    65341 ggcgtgaaaa aagtgatcct tcatgaagac aatacgttag agattacctt agaagatcct
    65401 gaagctggga aagaaatctt tactcgtgcg actcagttcg gctacattcc tatgtttaac
    65461 cagcaaccgc caactttgga agagattttc aaattgaaag caggtgaaat cgatgcgtaa
    65521 gttttggatt attaccaaag atgtctattt aaaaaatgtt aagtcgattt ctttcttgat
    65581 catgatatta gtccctttta tcatgctggg tatcatttat gtagcaggaa actttgctca
    65641 acaaaatagt gatgtcaata aaatcggcgt attggctgat aatgagcaaa tcagtcagca
    65701 aatgagccaa gtcaaaacag atgattttga gttcaaagca gttgattctg aagaaaaagc
    65761 acaaaaagag ctttcggaag aaaaaatcga tgcgtattta gtagtctcaa ctgagaatga
    65821 taagataaat gggatgcttt atagcgaaaa ttcattagga caaagtacac aactactgat
    65881 acaacaacaa ctgactggct tgcaatcgat gcttcgagcg agtcaattag gcatttcacc
    65941 agaagaagta gctagcttga gccaacaagc aagtttgact cgacaaaaag tcaattttga
    66001 ttcaaaagga aaaatgacag tcggagaaga taactcgaca gtccaatacg tcgtaagtta
    66061 tgtagcaacg attgtcttgt tcattattat tttgacgtat gcgcagatca ttgcacaaga
    66121 gatcgcttct gaaaaaggca cgcggatcat ggaagtgatc ctgtccagta cgactgcaca
    66181 aaagcatttt tacggaaaat taacaggtgt tttacttgtt gcattaacgc aaatggcatt
    66241 atacggtatt atttttggta taggatacag tcaattcaaa gatatggaaa tggtcaaaaa
    66301 tatattagac ggtatctcat tggataactt gattggacca ttcttgtggt attctcttct
    66361 attcatgatc tttggcattt tgattttttc tgttttagca gctttatgtg gctctttggt
    66421 caacaaagca gaagatacag caaaagcaat tttgccagtg acttatctat ctctaggcgg
    66481 atacatgctt ggattgatac taggagcttc agatccaaac aatatcgtta ttcggatcac
    66541 ttcgtatatt ccattcttat cttcatatat tatgccggtt cgcttagcaa atgagacagt
    66601 cggtatgggt ggagcattga tttccttgtt ggtacttgta gccgtaacat tcttattgat
    66661 gatcttgtct gcaaacatgt acaaatcgaa tgtactcgtt tatagcgaag gcggattatg
    66721 gagttcattg aaacaatcga tttcaattat gaggaatgaa cgaaaaaaag cataaaacaa
    66781 tcctaaaata cagaaggaag ctggacatct attgttccca gcttcttttt gtatagacct
    66841 attttattta ttttactata ttggatatat attcattgaa aatagtgtat aacaacttta
    66901 taatattgag tataccaatt tttggaggcg ttttaatgga ccgttattta gatttacttt
    66961 cagaaaaatt cccctcaacg gaggatgtca tcacggaaat catcaatctc gaagcaattt
    67021 tgcagcttcc aaaaggaaca gagttatttt tgagtgatat acatggcgaa tttcctgctt
    67081 ttgatcatat tctgcgtatc ggttcaggaa atcttaaaga aaagatcaaa gacctttttt
    67141 ctgaacaaat gacggaaacg gatatcagcc aattcactat ttttacggct tatccagaat
    67201 atgcattaac gactgattgg tacaaagaac aagataaatc gcagctgatc catcatttga
    67261 tcgatctttt acggtttacg acagtcaaat atacccggtc aaaagttcga aaaggattgc
    67321 cgaaagaata tagctatatc attgaggaac tcttgtatat cgatgaccgt atcaatggaa
    67381 aaaaagacta tgtaaaaaaa atcattgaac aacttgtttt gatgaaggaa gaagaaaaat
    67441 ttttaacgaa acttgcacag acgatccaaa aatctgtcat cgatcatttg catatcgttg
    67501 gagatatttt tgaccgagga actcaagcag ccaaagtgat ggatcgaatc atggattttt
    67561 cttctgtaga tatccaatgg ggaaatcatg atattttgtg gattggtgcg tattgcggct
    67621 ctgaggcatg tttactgaca cttttacgga ttgcagcacg ctataattat ttatttgaat
    67681 tagagaaaga atatgggttg aatttacgtc cattgttttc ttttgctcat caaacttatc
    67741 agaagaatcc agtatttgcg cctaaaaaca gtaaaaatct atccgaaaga gagcaagaag
    67801 aattagaaaa aatccatcag gcactttcta tccttcaatt caaatcagaa catcagttat
    67861 tggatcgtcg acctgaattt aaaatggacg atcgtaaatt gctggaaaaa atcgactatg
    67921 aagcatcaac gattgattta gaaggtcagc tctatgagtt gaaaggaact tgttttcaaa
    67981 cgatccagcc agatgatcca aaaaaattct tggaagagga acaaaaagtg attgatagtt
    68041 tgatgtattc attccagcac tctttgagaa tgcaaaaaca tatgacgttt ttgatcgaaa
    68101 aagggggaat gtatctcacg aacaatcagc atgtgctgtt tcatggctgt atacctgtag
    68161 acgagaaggg acagctctta gcatttgaat tagaccaatc ttatcgcgga aaagaactgc
    68221 tgggcttttt tgaaaaacag ataactgaaa gcgcaaaaga tctgactgca aaagaagatt
    68281 tagcaaccga tttgatttgg tatgcgtgga gtgggccatt ttcgccttta ttcggcaaga
    68341 gtaaaatggc gacttttgaa cgttattttc tcacagagcc tcatacgcac gtcgagaaaa
    68401 gcaatcctta ttatcacttg cgagatgaag agtggttcag tgaaaaaatt ttagcagaat
    68461 tcgacacaaa agaagaaggg tcagcaatca ttaatgggca cacgccagta aaagtaaaaa
    68521 aaggggagtc accgatcaaa gcaaatggaa aagtatttgt cattgacgga ggtttatcca
    68581 aagcttatca aaaaacgaca ggaattgccg gttattcact attatgcaat tcttatggtt
    68641 tccaaatcgt gacacattat ccgtttttgc ctattgaaca acaatttgca aaaaaatccg
    68701 accaaacaaa tgtgaaaaaa gtaatcgaac agcaactacc acgcaaactc aatcgtgata
    68761 caacaaaagg tatggaactg cagcagcaga ttacccagct caaaaggctg ttggactatc
    68821 gaaaggacga ttgagaagaa ttccagtgaa cattgttcca tagactggag actgagacaa
    68881 aagtcgtgtc gcagtctctt tttccggata aacggtgttc ttctgccaac tcctcggtca
    68941 caagtcacac tattcaacaa acatgaaaag ctgttttttg aaattgctcc ttgtgactca
    69001 gagttgaacg gcaggctcac gacctcttgg tataaacggt gttcaaaagc cagtttctcg
    69061 gtattaagcc aaatttatgc aaaaatgtga aaagccattt tcacaaaatt tttcttaata
    69121 ctcgaaacta aacagctttt tcacaacccc ctcagaaagt ctattaaaat tcattcacaa
    69181 agaaatcgaa taagcgctgt tcagatggat gtacacggtg ggtaagttcc ggatgccatt
    69241 gaacaccgag gattttatgc atatcatctt tgctttgaac cgcttcaatg agtccatcgt
    69301 tagaaaaagc gatggctttt aataaaggtg aaagatcttt gactgcctga tgatggtaag
    69361 aattcacaaa atatggatcg gggagaaggt tgcttaacaa actgtctgaa acaatcttga
    69421 cttcgtgagt cgtaaattgc ggggcagtgg gctgttgttc atgttttact gaccactttg
    69481 gatataatga aagatcttga taaagtgtac cttccaaaac gacattcaat agttggagtc
    69541 cccggcagac tgcaaaaatt ggttttcttt gtttcaatgc ttccaagatc agtgcctgtt
    69601 caaattggtc tcgttgaata tttgtttccg ttagctttgg atgaggatct tccatgtaaa
    69661 gttgtggact gacatcttga ccacctgcaa gaataagttt gtcgatttgt ccaatcagtt
    69721 gaggagctga atctggagac atgactggca gaataagagg caatccttga gcatctaaaa
    69781 ctgcatccac gaatccttgc ggtgtatagc tcacttgatt tccttggaaa gtatctgttg
    69841 ctcgaatcag ttgatttccg gcaatgccga tgattggttt catttgtatt ccccctaaag
    69901 tagacttatt gtaacaagga tttaaaaaaa attaaactat gtaagacttg cccctatact
    69961 tatctgttct tgctgtgtta ctatctgtaa agagaaattt cgtgtgaaat tcatgacgat
    70021 agttgaaaat attgcttaat ttgttataat aaaaagtaag cagaaataaa aaggttgggc
    70081 gtaagcttca aggatctagt tcttcaaggg gtgagaagga cattttattg aaggggcctg
    70141 cctatactaa gttatcttta gaggtacata ctttcaatga aaaaagaaag catgtacctc
    70201 ttttttaaat cgaaaggaag tgaagcaagt gttagaagct ttggaacaaa tccgaaaagc
    70261 agaagaagaa aatgaaaagc gtgctcaaac actgcggcag cagctgaaga tctatgcaac
    70321 agaaaaagag caggaattgg aaacgatcca aacaaactat cgacaacaac taaaacagtt
    70381 ggtggaagaa aaagaacaat ttgaaataca agaattagaa aaagaaaaaa tgaaattgaa
    70441 agcagaagca gacaaggtgc aagcaacttt gaaagatcaa tatcaaaagc atcagagtca
    70501 agcgatcggt gcgatcattg aaagggtgaa agaaacttat ggccgtcact aagatggaaa
    70561 aagtgaccct catttcagat aaaagaaatc aggagaggat tttacaagca gtacaaggaa
    70621 tccaaaacgt tgaaatccgg gatctgtatc aaaatagaac aaacaaccag tgggtggaga
    70681 agtattttcc agataccacg attattgata aagaagcaaa attaagcgct ttaggtaatc
    70741 ggttgaaaga catccaagaa gctatccaat tcatacaaca ccacggcgat agccgtcaaa
    70801 agaaactcca tttgaaacgt caagaacttt ccttacaaga tttggaagcc aattattccg
    70861 aagaaaattt cataaataaa ttgaaagaag tccttgattt aaaagaaaag tgggaacaac
    70921 taactgaaga acgtgatcgt ttagaagaag aggaagaatg gcttcttcat tggcaacagc
    70981 tggatattgc tccaagtatg tatgcaagta agacgaccat ttttgagatg gggactgtga
    71041 gtgcagcaaa ttttgaaagt ttcaaggaag aactgagtaa gcttgatgac gtttatatgg
    71101 aagaaataga ttatacgcca aaacaagttt atctttcgta tgttgcttta aaaaaatcag
    71161 ttgctgttat agaagaaatt gctgggaaat acgggttcaa taaagaaacg tatccttatg
    71221 aacaaaatcc taaagaaaaa ctgcaagaga ccaagcagca attatccatt gttcacgagc
    71281 agcaaaagaa gataacgaca gcgttaggtc agtgcagtgg ctatatccaa gaatttgaat
    71341 gggtagaaga agtcacactt gccgttgcag aacgagaaaa aataaaagaa cggtttatcc
    71401 atgcgactta tctgatcgtt ttgcaaggtt gggtagatgc agaagaaaaa cagaatttgc
    71461 tgcatgtgtt aaacgaaacc gtatcagaag aagatatata cgtcagtttc gaaacaccaa
    71521 actcagaaga gattcagcag gaagtcccta ctaaattgaa aaaccatccg cttgtcgaac
    71581 cttttgaatt gctgactgaa atgtacagtc tgccaaaata tgaagaagta gatccaacac
    71641 cttggatgac accattttat cttgtcttct tcgggatgat ggtcgcagat gttggttatg
    71701 gtttgctgat gctcattggg acaatactag ctcaaaaact acttgttcta ccacgcggga
    71761 tgaaacgttt cgtaaaattc tttgagattc tctcgatacc atcgatcatc tggggattga
    71821 tctacagttc atttttcgga cagtcattac caaaagaact gtttggcatc cgcttgcctt
    71881 tcccaatcct atctacgacg gatgacgtca atacgatttt gattttatcc gtgattttcg
    71941 gtctgataca gattttggtt ggattatttg tggcagcaaa ggaaaatatc aggagaaaag
    72001 attacttgag tgctgtcagt gatggatttg cctggcaagg gatcctaatt gggatcgtta
    72061 ttgcgttggt tggtgccatg ttgataaaaa atacagcatt tgtttacctt ggcgctgggc
    72121 tatcgatcat tgctgcctta tgtatcttga tcgttccgat tatccaaacg ccgtctaaag
    72181 tcaaaggtgc tgccaaaggt gcgtataatc tttacggact gaccggctat atcggtgatt
    72241 tagtcagtta tacacgtttg atggcattgg gtatttcagg cggaagtatt ggagcggcat
    72301 tcaatatgct agttgctttc atgccgccag ctgctcgatt cagtgtaggg atccttttga
    72361 tcatcgcttt acacgcactg aatatgtttt tgacactgct aagtgcctat gtccatggcg
    72421 cacgattgca gtatgtcgaa ttttttggga agttttatac aggaggcgga cgtgcctttg
    72481 atccgctgaa aacggcggaa aaatacgtca acatcaatca caagaaaaaa aacaataaat
    72541 aattggagga tttttatata atgatggatt acttaattag tcaaaatggt ggaatggtat
    72601 ttgcggtatt agcgatggca acagcgacga ttttttcagg gatcggttca gctaaaggtg
    72661 ttggaatgac aggtgaggca gcagcagcat tgacaacaag tcaacccgaa aaattcgggc
    72721 aggctctgat tctgcaattg cttccaggta cgcaaggttt gtatggattc gttattgcct
    72781 ttttgatttt tatcaactta ggaaatgaca tgtcagttgt acaaggactg aactttctag
    72841 gtgcttctct gccgattgct tttacaggct tgttttcagg tattgcccaa ggaaaagtcg
    72901 cagcggcagg tattcaaatt ttagcgaaaa aacctgaaca tgctacaaaa ggaatcattt
    72961 ttgctgcgat ggttgaaaca tacgcgattt taggtttcgt tatttccttc ctattagtgt
    73021 tgaatgccta agcataaagg aggaaaagca gatgaacgcc attgaaaaaa tcatctctca
    73081 gatgaacgaa gcagcagagc aggaaagagc ggcgttagaa caagaagagc gaatgaagat
    73141 cgatcaaaac tttgaacaaa aacgtacgca agttgaaaca gaacatcaaa aacaaaaaga
    73201 aaaacaaatc gaattactcg aaaaaaaata ccgtcagcta aggaatcgcc agcaagtaga
    73261 agtacgacaa gaaaatttga atgcgaagca ggaattttta agacgattgt ttgcagatgc
    73321 ggtaactgaa atggaaaatt gggatgaatc tgaacaaatc cagtttatca aaaatgcatt
    73381 gtattcatta cctttgacag gaaaagtagc attcattgct ggagaaaaat cagcagccta
    73441 tctttctcag acgttgttgg atgaatggaa caatgaactt ccctttatga tggttttaag
    73501 tgatgaaact gttgctgatc aagcgggttt tctgataaac gatcaaggag ttcagtataa
    73561 ttttcttttc agcagccttg tacaagatat ccaaggaacg atgagttttg agattgccaa
    73621 tcaattattc gaataaggag ggatcagtgt atggaatacc acgaactaaa tcccttgatt
    73681 cgcggaagag agcttgaact tttgtccaat gagacatttg aacggatgat tcaaacaaat
    73741 tctgtcgaag cacttggtga aatattgaaa tccacgattt acagtccata tatttatgac
    73801 ggatatgaat atgacttcga acagaatctt ttaaaggagc agagccgtct atttcgctgg
    73861 ttaaaggaat cagcaccgga gcctgaaatc gtttggatct atacgatgcg ttatactttc
    73921 cataatctga aggttttgac aaaagctgag atgacaaatc aaaatctgga ccatttgtat
    73981 atcgacgatg gattttattc attagaaacc ttgaaggatg ccattcatac gcaagtttca
    74041 aatgaacttc ctgaaagcat tatggacagt atacgagaag tacgtgatta ttttgaagag
    74101 tctaccattc ttcagggaat tgacgtgatt tatgatcgac agtttttgac agagcagcga
    74161 cggcttgccg ataagctagg atatcaagaa ttgctgacag aagtcattgc ttttattgac
    74221 ttgaccaata tcacaacgat ggctcgagga atattgcaga aaagaacata tgggttcatg
    74281 acgacggtac tttccagctc gggaagtatc gaaaaagaag tatttttgaa ctttgtagat
    74341 aaagatatgg aagattacac gaattttcta ttagagacag attatgctga ttttctgcgc
    74401 cctgtcatcc gtgagggaaa tattgatctc gtaaagcttg aacagttgaa agatgattat
    74461 ctaagttcat tgtatcaaga agcacaaacc caggctttcg gaccactgcc actactagcc
    74521 tttttgaacg caaaagaggt agaaagcaaa aaccttcgtt tactggttat cggcaaaaga
    74581 agccatttcg aatcagaaac aatcagaaag cgggtgagac aagtctatga cgcataagat
    74641 cggtgtagtt ggcgacaaag attctgtttt gccattcaaa ttgtttggct ttgatgttcg
    74701 ttatggtaca accaagcaaa ccgttcgtca ggcaattgaa gaaatggcaa agaatgagta
    74761 tggcgtgatt tatgtcacag agcaatgtgc agcattgagc ccagaaacga tcgaacgtta
    74821 caaggaacaa atgatacctg ctatcgtatt gattcccaat catcaaggat cattagggat
    74881 agggctggaa gaaattcaaa aaaacgtaga aaaagcagta ggtcaaaata tcttatagta
    74941 tgaaaaggag atagaaattt tgcaaattgg aaaaatcata aaagtctccg gacctcttgt
    75001 aatggctgag aacatgtctg atgccagtat ccaagacatg tgtctagtgg gagatctagg
    75061 agttatcgga gaaattatcg agatgcgtgg cgatgtggcg tctattcaag tatatgaaga
    75121 gacttctgga attggtccag gcgaaccggt tcgctctact ggtgaagctt tatctgttga
    75181 attaggacca gggatcattt cacaaatgtt tgacggaatc caacggccat tagatacctt
    75241 tatggaaatc acacaaagta atttcttagg gcgcggagtt caattgcccg cattggacca
    75301 tgagaaaaaa tggtggttcg aaccaacagt agaagccgga gaaacggtga gtgctggaga
    75361 tgttatcggg atcgtagaag aaacaaaagt tataaaacat aaaatcatgg tgccaaatgg
    75421 gataaaagga acgatcaaaa caatcgaaaa aggttcattc actattgatg aaacagtatg
    75481 tgtcattgaa accgaaaatg gtgacaaaaa tttgacgatg cttcaaaaat ggccagtaag
    75541 acgtagtcgg ccaatcaaag aaaaattaaa cccggatgca cccatgatca ctggacagcg
    75601 agtgattgat acattcttcc cagtgacaaa aggaggagca gcagctgtac ctggtccttt
    75661 tggtgcaggg aaaacagtcg ttcagcatca aattgcaaaa tgggccgatg tggacatggt
    75721 tgtctatgtg ggatgtggcg agcgtggaaa tgagatgacg gatgttttaa atgaattccc
    75781 tgaattgatt gaccctaata caggagaatc gttgatggaa cgtacggtat tgattgctaa
    75841 tacatcaaac atgccagtag cagctcgaga agcttctatc tatacgggaa tcacaattgc
    75901 ggaatatttc cgtgacatgg gttatgacgt tgctatcatg gcagactcca cttcacgatg
    75961 ggcagaagca cttcgtgaga tgagcggacg tttggaagaa atgcctggtg atgaaggtta
    76021 tccagcttat cttggttcac ggcttgcgga atactatgaa cgatctggaa gagtcattgc
    76081 attaggatca gaaggtcgcg aaggaagtat aaccgcaatc agtgctgtat ccccgtctgg
    76141 aggggatatt tcggaaccag tcacacaaaa tacattgcgg gtcgtaaaag tattctgggg
    76201 tcttgattcc agtttagccc aaaaaagaca ttttccttcg atcgattgga tacaaagcta
    76261 ttctctttat tcaacagaag tagggaagta tatggatcat atccttcaag ctgactgggc
    76321 atccatggtc accgagggca tgcgtatttt gcaggaagaa cagcagctga atgaaatcgt
    76381 gcgtttggta gggattgatt ccctttcaga taatgaccgt ctgacattag aagtggcaaa
    76441 atccattcgt gaagattatt tgcagcaaaa tgcttttgat gatgtcgata cattcacttc
    76501 aagagagaaa caattcaaaa tgttgaagat gatcttgacc tttggtgaag aaggacgccg
    76561 tgcgttgtcg ttaggtgctt atttaagtga gatcatggac ggtaccgtat cgattcgtga
    76621 aaggatcgga cgaagcaaat atatcccgga aacagaatta gaaaaactag atcaaattat
    76681 tggtgaaatc aagcaaacga tgcaaacgat cgtttcagaa ggaggcatga gcaatgatta
    76741 aagaatatcg tacgatcggt gaagtcgtcg gtccattgat ggcggttgaa aaagttgctg
    76801 gtgtcaaata tgaagaatta atcgaagtcc gtatgcaaaa tggcgagatt cgtcgtggac
    76861 aagtattgga agtccaagaa gataaagcaa tggtccaaat attcgaagga acaagtggta
    76921 tcaatttacg tgactcttct gtacgatttt taggccatcc tttagaacta ggtgtatcgg
    76981 aagacatgat cggtcgagta ttcgatggtt tgggacgacc gaaagataac ggaccagaga
    77041 tcctgcctga aaagcatttg gatattaacg gagaagtaat caatccagta gctcgggatt
    77101 atccagatga gtttatccaa acaggtatct ctgcaatcga tcatttgaat acattagttc
    77161 gtgggcaaaa attaccagta ttttctggct ctggtcttcc tcataaagaa ttagctgctc
    77221 agatcgcgcg acaagcaacg gtactcgatt catcagatga tttcgccgta gtctttgctg
    77281 ctattggaat cacttttgaa gaagctgaat ttttcatgga agattttcgt caaacgggcg
    77341 caatcgaccg ttctgtcatg tttatgaatt tagcaaacga ccctgcaatc gaacgtatcg
    77401 ctactcctcg tatggctttg actgctgcag aatatcttgc ttatgaaaag ggaatgcatg
    77461 ttttggttat catgacagac atgaccaact atgcagaggc attgcgagag atttctgcag
    77521 cacggcgaga agttccagga agaagaggat atcctgggta tctttacacg aacttagcta
    77581 ctttattcga acgagcagga agaatccgcg gactaaaagg atcggttact caaattccga
    77641 ttctaacaat gccagaagac gataaaactc atccaatccc tgacttgact ggttatatta
    77701 cagaaggaca gatcatcttg actagagagc tttacaagag tgggattcag ccaccaattg
    77761 atgtactccc gtctctttcg cggttaaaag ataagggaac tggacccgga aagacaagag
    77821 aagaccatgc agctacgatg aatcagcttt ttgcagccta tgcacaagga aaacaggcaa
    77881 aagaattagc cgtagtttta ggtgaatctg ctttatctga tgtagacaag atctatgcga
    77941 agtttgctga gcggtttgaa aaagaatatg tcaatcaagg attctacacg aaccgttcga
    78001 ttactgaaac acttgatcta gggtgggaac tgctatcgat gttgccaaga accgaattaa
    78061 aacgaatcaa agacgacatg ctggacaaat atctgccaga agggaagtga gttctgatgg
    78121 cacgattgaa tgtgaatccg acccgcatgg aattgactcg attgaaaaaa cagttgacaa
    78181 ctgccacaag agggcataaa ttattaaaag ataagcaaga tgaactgatg cgtcaattca
    78241 tcctgttgat tcgaaagaac aaccagctgc gtcaagaaat ggaagagtct atgacagaag
    78301 caatgtctga ttttgtattg gcaaatgctt cgatcacgga acctttcatc gaagaattat
    78361 ttgttttgcc ggcggaaaac gttgatttgt ctatcgtaga caaaaatatc atgagtgtaa
    78421 aagtacctgt gatgaatttt gaatatgatg aacagctgac agacacacct ttggaatacg
    78481 ggtatttgaa ttccagtgcc gaactggatc ggtcaatcga tcggtttact accctgcttc
    78541 caaaactttt ggaactgaca gaaatcgaaa aaacttgtca actgatggcg agtgaaatcg
    78601 aaaagacacg tcggcgagtc aatgcattag aatatatgac gatccctcaa ttagaagaaa
    78661 cgatctatta tattcgtatg aagctggaag aaaacgagcg cgcagaagta acaaggttga
    78721 tcaaagtaaa aaatatgggt accactgact aagtggtatc tttttttaaa agaggaaaac
    78781 gatgattaaa caaagcaaac aaataaagaa acgtttgccg gctgttcagc ttctcgcatt
    78841 aggatttttt ctcctgattt tagttggcgg cggcctactt accctaccat tttttagtaa
    78901 tagtgggcat gggacaaatt ttatcgatgc gcttttcact gcaacttctg ctgtctgtgt
    78961 aacgggattg acaacattga atacagcaga gcattggaac agtgctggtc aatttttgat
    79021 catgcttttg attgagatcg gcggtcttgg ttttatgatg gttccgattc tatgctttgc
    79081 attgataaag aagaaagtca gtctcagcac acgtattata ttaaaagaag cgctgaatct
    79141 agaagaagta tcaggtgtga tgaagctcat gctttacatc ctaaaattgg cctttgtgat
    79201 ccaattgatt ggtacggttg ctttatcttt tgtatttgtg cctgaatttg gctggttgaa
    79261 aggtatctgg tacagtttgt tccatgcaat ctctagtttt tgtaatgcag ggtttgattt
    79321 gttaggagac agtttagcca atcaccagca aaatgtttat ttgatcatgg tggtatctgc
    79381 tttgatcatt tctggtgggt taggcttcat cgtatggcgt gatttactgg aatatcatca
    79441 gaaaaagaag atgacgattc attcaaaaat cgcattaacc gttacaggta cccttttatt
    79501 aggcggattc gttgtgttct ttttcacaga gcgcaatggg gcaacgctag tggaagggaa
    79561 tatgtttcaa cgattggcaa acaccttttt tatgagtgtg acacctagaa cggctggata
    79621 ttattcagtt gattacctcc atatgagcca tgcaggtctg attttaacga tgtttttgat
    79681 gtacatcggc ggaacatctg ggtcgacggc cggcggattg aaaacaacta cgttaggtgt
    79741 gttgctgatc cagatgcgtt cgatgttgaa aggacgtacg agagcggaag catttggccg
    79801 taccatccga caaggcgcag tgttgcgggc acttacttta ttttttgtta cgttgacgtt
    79861 gtgtgtagtc gccatcatga ttttatcggt gactgaaacg atacctaaaa cttctggcat
    79921 cgaatatatt gcttttgagg tcttctctgc gtttggtaca gtaggtctta cgatgggatt
    79981 gacgccagac ttgactgcaa tagggaaatt gatcattata gcgcttatgt acattggacg
    80041 agttggtgta ttgactgtgg tcttctctct gatgacaaaa gcacaaagaa cacaatcaaa
    80101 atacaaatat ccagaagaaa gtgtcatgat tggataattt catcttctga cagaaaccta
    80161 gtgatttagt aaaataagaa aataaaataa tttttcttgc ttcttggata ctttaagtgc
    80221 aaaatgttcg tttatttttt gaggcactac ccgttgttga acctcgggta gtgcctcttt
    80281 tttattgaaa ggaatcaata agatttgatt cctttattta tcaataggtt ataattcata
    80341 tttttttatt ttttctttta cgatacttag tccagaagct aaaatttcaa ggttattaga
    80401 ggatagggaa attcgaacga atgcatctgg ttgcgtacgt gtagtaaagc gtctggaatg
    80461 ataaagtcgg ataccgttag caagaaagtc attctcaatt atcttagggt caatctcagg
    80521 atcaactgga agaattcgat agtaagggac acgattcgtt ggtttttcta ctttgaaaag
    80581 agaatcaaaa agctgattgg ctctttttgt aagacttaat ttagtttcta agatcctatt
    80641 tgcttcattt gaatggagga tttgagtgat gacttccaca tctaatccag aagttttcac
    80701 atttatatta aaaattgctt gttctatctt gctttggaca tgtactggaa ctacaagata
    80761 agcaactcgc aatccagaac aaataaattt tgtcattcca gctaagtaga ttgtttggtt
    80821 aggtaataaa ttttggaaag gaggaatgat cgtatgttga tagtaagttg ttaaaaatga
    80881 atggatatca tcttcaataa cccatagacc ttctttttca atcacttcgg ctaattgctc
    80941 tcgtcttttg tgagagattt gaaaccctat aggattatta caagaaggca taagaaagac
    81001 accatgaatc ttcttttttc tacattcctg aatcaatata tcaggtcgca ttccttgctc
    81061 gtcaaaatca attggaacga tctctaaatg atataactga gccaattcaa tgaaattagc
    81121 gtatgtatat cggtctgttg ctattctatc acctggagag aaaagtgcag aaagtgtgat
    81181 agccaatcca ttttgaacac cggaaacaat agatagagat tctaaggacg gaatgactcc
    81241 ttgagttttt aaccaatttg ctgcagtagt caattgaaaa tttgtgcctt tgggatcttg
    81301 gtaattaagc aaaccaacaa gatttgggtt attactagtt gattgaataa acgggacaac
    81361 gaatttatta cattcttcaa aagaactaac cagaccaaaa tcaatgatat gttcggttac
    81421 ttcattggta gagatggtga tggactcaaa gacattggga gaaataaatg tgccacttcc
    81481 aatattcgta tacagcaaac ctttctcaat tccatattta taagccttgc caacggtagt
    81541 aaaatttaaa tctaaataat cagctagctc tctttgggag ggtaactgag tgtttttctg
    81601 taatttattc tttaaaatat cttgttctaa ttgttgaatc aacgatcgat aataaggacg
    81661 cttcaatttt tgtttgtctg gtcgccaagt taacgggtaa ttgtcataag aattaatagg
    81721 cattttctcc actccttaaa attgtatacc atacaatttt accattgatt gtattgattt
    81781 tagaagttaa tcttttgtga ggagggaatt gtctatgaaa attattaatt ttgaggaagt
    81841 agtagcttct tttagttttg aagaagcgat tcaagtaatg aaaaaatgtt tttttgatta
    81901 tgaaagtggt aaaatcagcc aaaatcctcg attggtggaa attttacctg acggaaaagg
    81961 caaaaatatg tttgcgatga tgcctgctta tttgggggag aacagatatt ttggcacaaa
    82021 agtcattacc gcttttccgg ataatcatca gtatcattta ccttctcatt taggagagat
    82081 tttcttgttt gatgctcaaa acggactacc caaagcattg ataaacgcaa atgcagtcac
    82141 ctggattcga acagctgctg tatctgcgct ggcaacagat tacttagcaa atccgcatgc
    82201 agaaacactt gctttaattg gagctggtca acaagcattg tcgcatttga ctgcgatttc
    82261 taccattcgt cccatcacta cagtgtttgt ttacgatatt ttagaagaaa gacgaaatac
    82321 ttttatcgct aaagctaaaa aacagtatcc taaaataacg tttataaatg caatatcagt
    82381 agaagatgca gtacgtccag cggaaatcat ttgtacgttg acctctagta aagaggcatt
    82441 tcttcaaaaa gagtgggtaa gggaagacgc acatatcaat gctgtgggca catttactcc
    82501 tgatacaaga gagataagta catcgttgat ggaaacttct caaatctatg tagatgatta
    82561 ctcagctgcc ttaacagaaa gcggggacct gcttatagcc atggcagaag gagatttaga
    82621 ggaatcttgt attgttggta cattaggcga attagtttct gagaaaaaaa cattttataa
    82681 aggagaatcg aggccgacga ttttcgacgc agttggtcta gctattgaag atctttgttg
    82741 tgcagaatat atttataaca aattagagaa aggggcttta aaatgaactt agattattac
    82801 gtagttgatg catttgcaga tgaggtgttc aaaggaaatc cagcagcggt ttatgtgcta
    82861 gaagaatggc tgccagaagg tacgatgcaa aaaattgcca ttgaaaacaa tttatctgaa
    82921 acagcattta cagtgaagaa aaaccaagaa tttgagctta gatggtttac gccagatcga
    82981 gaaatcgatc tttgtggtca cgcgacatta gcaacagcat ttgttttatt taactattac
    83041 aaaatacctg atgaaacgat taaattttct actcaaagcg gtaatctatt tgtgacaaga
    83101 attaaagatt attattacat ggattttcct agtattatgc cgaaaaaagt gccgatattg
    83161 tctgaatatg aagaagcgat tggggctaag attaaagaag cctacttagc acgtgattta
    83221 tttttcgtat tagaagatga aaaaacggtg gctaaattgc agccagattt tacagctatc
    83281 aaaaattttg aattaggaat aggagtcatc gtgacagcag aaagtgtgca aaaagacttt
    83341 gtttctagaa ccttctttcc aaaattaaca atcaatgaag atccagtatg tggatcagca
    83401 cattctaatc ttattcctta ttgggcagaa agaatgaata aaacaaaatt gtcagcttat
    83461 caaatgtcat caaggggcgg ggatctagaa tgtgaattaa aagaagatcg tgtgataata
    83521 ggaggaaaag cagttttgtt ttctaaaggt acctcgttta tttgatttct ttcaaatgaa
    83581 ttaaaaataa attggtggag agtggcaacc ttatagctac aatggttgtt aaaaaaagac
    83641 gcaaactttt tcaatttaat gaaaagtttg cgtctcattt taattattgg tgtttgtttt
    83701 ttattcaatc aagagtaaaa tgccccatac taactatcct cggatgactt cgattttata
    83761 accatcaggg tcaatgacaa agtagtaaga aggcgcagtg ccaggtaatc cttttaagtc
    83821 agtaatctca agaccagcag ctttatgttg ctcgtgtaat ttttctagat catcagctgc
    83881 tatagcgata tgaccatagc cgtctcctag atcatacgca ccatgatcat agttgtaagt
    83941 caactctaat tcatagtcat ccccaggaag tgtcaaataa acaagtgtaa atttgttttc
    84001 tggaaaatca cggcggcggc tttcttcaaa accaaatgcc ttttgataaa attcgattga
    84061 tgcttcaaga tctttcactc gaacacatgt gtgagccatt ttcatagatt catctctcct
    84121 tttcctttta ctcaatcata acaaaaagaa gtaaggaaat agttgatttg tgcttgttca
    84181 tgagaaattt ctcatgtaaa atggatagaa aataaaactg ttaaggtgga aactattcat
    84241 ggataaacca atttttggtg aaaaaaagca atttgctgat tatcaaaccc gttatgcagc
    84301 atatattgtc atagaaagag atcagcagat tgcagtaatc gaggctccaa atggtgcttt
    84361 ttttcttcct ggcggggaaa ttgaaggaga agagacgaaa gaagaagcga ttgtccgtga
    84421 gctgatagaa gaaatgggaa ttgtggcaga aatttcttct tatctgggag aagctgatga
    84481 gtatttttac tcgaattatc gtgcaactta ttattataat ccaggatatt tctttgttgc
    84541 tgattcttgg aagcgtatag gagaaccaac tgaaaagacc aataaaattt ggtgggtgag
    84601 ccctcaagaa gcgcttgtga aattgaaacg tggtagccac cgatgggcag tcgagagatg
    84661 gatcgaaaaa aataaaaact gaaagaaagc gagtagatca gctttctctc agttttttta
    84721 tttattacag tacatatttt ttgattgctt cagctacacc gtgctcgtcg tttgatgaag
    84781 tgatgacatt tgctgcttct ttgacaagag aaacggcatt tcccattgct actcctagac
    84841 cagcatattc aatcatggat aagtcgttct cgttatctcc gatagccatg atttcatctt
    84901 gatcaatacc aaggtgctgt gcgagattcg caactgccgc acctttactt gcttctttat
    84961 ttagtacttc gaagtaatag ggcgcacttt tgaccgttgt gtatttatca cggaaagttt
    85021 gcggtaaacg cgcaattgct gcatctaaaa tttctggttc gtcgatcatc atcattttga
    85081 cgatgttcat gtctggtgtc atttcttcag gtgttcgata ttttagcggc atcttgacta
    85141 aacttgcttc gtggatcgta taagcgctga tatctcgatt aggcgtgtag atcgctttgt
    85201 catcgatcga atggagatga ctgccgacac ggcgtgccat cacttcgatc tctaggaaat
    85261 cttcatgtgt cagtccgtga cgggcgatga ttttacctga tttcgtttgt tgtacgagtg
    85321 ccccgttata agtaataacg taatcattat cttgaaaaag gttcaactcg tttaactgtt
    85381 cctggacacc tggtaaggga cggccagtgc ataaaacgat cgaaacacct tttgcaacag
    85441 cagcggcaat cgcttctttt acttcttttg ttacttctct tttctcattt aataaagtac
    85501 catcgatgtc gatagcgact agtttgatag acataatttc ctccaatata ttttaattta
    85561 tttcaatcaa tgcgccatta cggatatggc tggcaaattc ttgataagtt tcgtcaaata
    85621 aatcataatg atcacgcaag gacggatcaa ccatttcttt tggaaagaaa aatcgctcat
    85681 ctccttgttc ttgtcccgct aatgcagcaa caagctgact aacctgtgat aattctatca
    85741 aagttccgtc atttcgcaaa atctcgattt gtgtgcgatg tctgccttgt tctgggcgat
    85801 aaaaatcata aggtagatcg tagctagaat tcacagcagt gtaataaaca ggattatatc
    85861 cgaccttttc tactaacaaa gtgagttctt ggactaattt tgaatcccgg ttgccagaaa
    85921 aagtagcaga tttcagtggt ttacgattca aaaaacgttt agctaaatca tttaaaatag
    85981 gatcagcaga ttcagaccat tgagtaaagt aagtgcccaa gaccccatca tcaagtttga
    86041 ggtattcttc taaagtaaag cttccgtcaa gaaatggcag aagtaattga gaatggagtt
    86101 caaaactgct ggcatcttct tgatacaact cgtgtgcgcg atgaagcaga tgctccaaaa
    86161 ttacttccat accacgggaa acaggatgga agtacacttg cacatacatt tgatatcggc
    86221 taacgatata atcttccact gcatgcatgc cactcatgga aaaagcgatc ccgccttcat
    86281 aaggacgaat cacacgtaat attcgggtaa gatcaaatgt tccatattct gttccagtga
    86341 aataagcatc ccgaagcaaa tagtccattc gatctgcatc gatctgacta gaaatcattt
    86401 ggacaacttg tgggttgggg taagtttttt ggatcacact agctaccttt tcaggaaaac
    86461 cttcttctac tcggttaaga atctgataca cttctgtttc tggagaagtg atgatctcta
    86521 cagtgatggc ttcatgattc gtatggaaga tatgttcaaa tgtatgagag taaggaccat
    86581 gaccgacatc atgcaacagt gccgcacata aagtcaccag ccgttcctga tcatcccagc
    86641 ctccgttgcc tattttttct tttgaaaaat ttcgagaaaa gatatcgcag attcgtcttg
    86701 aaatctcata aacgcctaat gaatgagtaa aacggctatg ttctgctccg tgaaaagtga
    86761 aagaagaagt gcctaattgt ttaatgcgtc gtagacgttg gacttctttc gaattgatca
    86821 aatctaagat tacttgatgc tggacatgga tatagttatg gactggatca cgaaaaactt
    86881 tttccatagg cagcatttga tatttataag gggttgtcat aatgtagctc ctttatgtta
    86941 ttacgttgtt ccattctctg gatttggttg ttccattgct ccagctggat ttcttttttt
    87001 agccagtcgg tagaatcctg taaatcactt gcagaataca gcttttcaaa agcttttgca
    87061 aatgcttctt tgacttcttt tacaaaaagg ggttggtcaa gcagttcttc aagtgttgcc
    87121 attgtagcag gatccactgc aggatagcca tttgtaccaa agtcttcttt taaagcagat
    87181 tgataaaatc gcttcatgac ttgcccgcgt ttttcctgat taccgttgac acttaagtac
    87241 atcataacag aaatcccatt tttgatccga cgctgagcga taccggcaaa ttttttgcca
    87301 tggatgctta aatcataagt tccaggacaa taagaatggg tgatttcgaa tgcttgtatc
    87361 ggtgcctttg gaaaagcgta tttagtcaat aggagcattt gctcgtaagc gtcatctatg
    87421 gttatttttt ttgtgtcact ttgggggaaa atcaaagaaa tattcaaaat tccttcatct
    87481 gatacgatcc ctaatccacc tgaatttctg atcactggag cgtaacctgc atctttcagt
    87541 gtttggatcc cgtcacttag aaaaggagtt cgaacatcct tcatacctaa gatgactgtg
    87601 cagtcatatt gccagaaatg taaaaagatt tgctggtgtt ctttagaata ttccgttaat
    87661 atatctgtta atgcaaaagg ggaaaagtcg tttttttgat aaatgtgctg atctagtcga
    87721 atcgcagggt tcattcaacc ggctcctttg tataaattca tattttctac aatattatac
    87781 tctaaaatca aagagttgtt ttggaaaaaa ggttttctgt aaaaatggac aagttggttg
    87841 acaaaacaaa agaaactagg aacaatgtag ctatgagaag taaaggagaa tgaataatgg
    87901 aattatcaca aggaacaccg atttcaatca aattgcgtac aaaagtaaaa cagcaagggg
    87961 aagtgcaaga tttttatttt gatttgaaag ggcaaatggt gacaattggc gatacgctgt
    88021 acatacgtta taaagagatt caggaggaga cgggcgatga gattcctgta acgatcaaat
    88081 tagttccaga tggtcatgta cagctgatcc gtgcaggaga aatgcggatg cgtttgaaat
    88141 ttggctataa agaacggtta gaaacatcct atcgaacacc atacggtatg atccagattg
    88201 ctacttttac gaaagaactg catgttagtt tgaaagaccg tcccacagca gggaaggttc
    88261 gaatcgatta tgatctgttc atgggaccgg aaaaaatcgg cgaatattat ttgaccttgg
    88321 attttacagc gtaaatataa aagaaaagtt tgattttttg tgtctgattt tgtatgataa
    88381 ggagtagact gtgaaaggac gtgtcctgat tggaaattag tgtatttgaa ggtgcaaaca
    88441 aaagcgaatt atcaatgatc gaagtagcac acgcgatctt agaacaacgt ggcgatgtca
    88501 tggatttttc tgatttagct aaccagatcc aaaactatct tgggaaatca gacagtgaaa
    88561 ttcgtgattc actcgcacaa ttttatactg acttgaatat tgacggcagc tttatctcat
    88621 taggggataa tcgttggggc ttgcgttcat ggtatgctat cgattcgatc gatgaagaag
    88681 taaaccatgg aatggacgaa gaggatgaag atactccacg tcgccgtaaa cgcaagaaag
    88741 tcaacgcctt tatcaatgat gatgaagacg cgatcgatta caatgacgat gacccagaag
    88801 atacagatct gacagaagaa gatgacgatg atctgtttga tgacgatgat gatgaagatg
    88861 aagaaatcgc tgcttataat tctgacttgc aagaaatcgg agcagatgac ccgacagatg
    88921 atgaagaaga cttgccagga aatatcgaag aagatttaag tatcatagac gaagacgatg
    88981 atgatgaaga ttatgaagag gaagaatttt ctgactctga aaaagaataa acattatttt
    89041 cttacgagag gttgtgacag agacgatcag cctatcagaa taaggaggtg tgacacgatt
    89101 tttgtcacac cttctttttt gtatataaaa atcccaagta aatacataaa aaataaaaaa
    89161 attgaaactt ttagcgcacc ttgtacgtca tattaagtga ggcagaaagg agtggagaat
    89221 gatttttact ggatataaga aaaaacggca gatcgaaaaa taccgtcacc tgctgaatgg
    89281 actcatcgaa actgattatc aaaaaatgtt ccgtatcacg atgaattacg tacatgataa
    89341 agaagaggcc ttagatgtga tgcaagatag ttttcataaa gccctgaact attttgaaaa
    89401 agaaaaagag atcgagcatt ttagtgcatg gttttatcgg atattgatcc gcacggcatt
    89461 agatagttgg cgcagacaaa aaaggacgcc tgtggactta tttgaaattc aagatatccc
    89521 ccaacagtta cctttagaaa cttccgttgc agagctccat atgattttag ataaaataga
    89581 cagtccggaa aaagagattc tgatcctcta cttttttgaa ggatttcgtt tgaaagaaat
    89641 tgcgactatc ttggatatga atgaaaacac agttaaaacg aaaatgtacc gctcattgaa
    89701 tgctttacgt caaatcctag aatgaaggag agaagagtgc catgtattcc caaaaagaaa
    89761 atttaaaaaa actaaagaaa acttataaag aacaagcaat tcccaaaggg cttaaagagg
    89821 agatccgcca gcgttttatt atcgaagagc aatcatttat aaaagcaaag cggagaaaga
    89881 gacgtctcca agggttcgga gtatctttgg ctatcgtaat gattacaaca agtagccttc
    89941 tttttaatag tcaagttcga agctttgcag aagatttacc catcttagga tcagtcattg
    90001 aattgatctt aggcgaacgc tttactgatc gatctgaaaa aatcgatatt caggtaccga
    90061 agatcaatac acaaaatgag aaagaaaata aaacaattca tggattaaat caaaaatact
    90121 ttcgcgaagg acaagcagat tttgaaaaag ctgaaaaaga atatggaaat tttgaaacgg
    90181 atcattacca agttttggga gattatcaga aaatcgtaga cgataaccgg tttctcgtga
    90241 ttgaaaggca gatcacccaa acagcagcag atagccatgt tgaaaaaaga tacgacacaa
    90301 tcgacaagaa aaacagtgtc cagctctcac ttccactttt attcaaagat gacacctatc
    90361 tatctgtttt gacaaaagaa gtcaaacggc agatggccga acaagtcaag gaagatccat
    90421 ctaagtacta ttggactgag caagatattc aagaagggac gatagaaaaa ccaacacttg
    90481 ttacgcctac acgaagtttt tatttgaaca aagagcatca attagttttg actttttctc
    90541 aatacgaaat tgctcctggt tatatgggta caccagaatt tgtcattcct aagtccgtga
    90601 caaaaacgat tttggcatcg gaagattatt tggatcatta gacgagaagt agttgcgact
    90661 agcagtttca attttcaagt aagtacaagt aaataataag aagagaaaaa gagaaagaag
    90721 agatatagtg aaaagaaatt atttagttat cagtattatt gctttatccg tgcttttgtt
    90781 tttcgaaatt acttcggtgg cctccttgat caccgaagta aaaggacaaa cacactcttc
    90841 ggagcattcg tcacaatctt tcaaacaatc agaacaatca accattaaaa gccaatcaac
    90901 tgaaacagct aacgtcaaag aagccattca agaatcagcg gaaaaggtac aaagtcagtc
    90961 atcacaatca acacaagaca gtacaaaaac gagccgagat ccggctgtca aaagcgtcgc
    91021 aatcagcttt gatgatggac caggagcgac cacaacaccg cagcttctgc gaatcttaaa
    91081 agaaaaaaac gtgcatgcca cttttttcgt cttaggagaa aatacggcgc agcatcctga
    91141 aatcgtgaag cagacagctg aagcagggca cgagattggc aatcacacat acgatcatca
    91201 gaatctggcc actctttctg cccagtcgat gacggaggaa gtgacgaaag cagacactga
    91261 gatcaaaaaa gtcactggca aaacccccac ttttgttcgt ccgccctatg gttctgtcac
    91321 gaatgtagga gcaacgatca tccagcgacc gatcatcgaa tggtctgttg attcagaaga
    91381 ttggaagaca agaaatcctg atttgatttt gcagaagatc caagcaacag tatacgatgg
    91441 ggcaattatt ttattccatg atatctatcc tgaaacgatt cgtgccgttc ctcaagtgat
    91501 cgattatctg aaagagcaag ggtatcgcat cacgacagtt ggggatttat tagggcatcc
    91561 aacggctgtc gagaactatt atggcagaaa cgatcatcgg ccagttcagt aagtgagaca
    91621 agtatcttta ataaataaca cattttaata agtagttgaa cacataacta ccttacttgc
    91681 aaaggcttaa caatatctat acaggtacaa caaaaaactg tccaccaatt ttctttggcg
    91741 gacagttttc acttaaaaat aaagaagcaa ctattcgtaa attatgctaa aatagcagta
    91801 gaacgcgtcc tgagggaatc gaacccccgt ctcaagaacc ggaatcttac gtgatatcca
    91861 ctacactaag gacgcaagca ctgggataat tgtaactaaa cagataaaaa attacaaggg
    91921 gattggacaa aaaaatgaaa tttgagcaaa atttttcaca aaaacagcag cagacacaga
    91981 aactagccat gacgcaacag ttgcaacagt ccatccaagt tttacaatat aacagtgagg
    92041 agctgttggc attcgttgag aatcaagcaa tggaaaatcc attggtggaa gttgttgagc
    92101 cggaatggca gccagattac ataaaagctt cttcatcttc ttatgaagga gaagagacaa
    92161 attacctaaa tcagattcct gatacaaaag ggtctttatt tgattcattg atcgaacaag
    92221 tccatttgaa ttaccgagat acttttttga ggaaaatcgt tctttatctt gtagaataca
    92281 tcgatttgaa cggatttttg acgattagtt tagaagaagc cggaaaagag attggagcta
    92341 cgcctatcca aatgctcgat gcgttgactc tgattcagca attagaacca gctggagtag
    92401 gtgcacgtag tttgcaagaa tgtctcatgc ttcaaacaga acgagatgat tatgcgccgg
    92461 aattagctta tatcgtgttg gaagaatgtt ttgaggaact ggtggagcga aaatggaaag
    92521 aaatcgcaca acgtttttct gttgatctac atgctgttca gcagatattc gactatttac
    92581 aaacgttgag tccaagccct ggccggattt tcgaccgtag cagcgaattg tacattattc
    92641 ctgatgtccg ggtattagtg gacgacgata aaaatgtaca agttatctca aaccgaaaaa
    92701 atcagccaaa tatacgcttt caagagagtt acttcaaaca aatgtcacaa caagcagata
    92761 aagaaactga aaattattta aaagaacgga aacaggaatt cgaatggttg aagaaaacga
    92821 tcctacaacg tggggataca attttgcggg ttgctcaagt cattgtttcc cggcaaaaag
    92881 ctttctttat cgacaaggaa cgtccaatca agcctcttac gttaaaggaa gttgcaactg
    92941 agatagatgt gcatgaatcc acggtcagtc gtgcagtcaa cgggaaatat ttggaaacag
    93001 acttcggtgt atttgaatta aaaaaatttt tcactacacg aattcctacg aatagtacag
    93061 aacagacaga agacctttca gcagatacag cgaagaaaaa gctgcaggaa ttagtcgatc
    93121 aagaagacaa aaacaagccg ttgtctgacc agaaattggt tgaattgctg aaaaaagatg
    93181 agatagcgat ctcaagacga acagtagcaa aatatcgtga tttattagga atcccgagtt
    93241 catcaaaaag aaaacgttat gataactaat cagtcaaaag actagaaaaa gtatttcact
    93301 ttttctagtc tttttagttg aaaaacgaga gcaaaactgt tagacttaca gtcgtgaggt
    93361 tgagatttcc ctttattgat gtgaaattcg aatagttaat ttcttttttt atcgtatatg
    93421 ggtcgtttta agtctacatt ggacgtaaag tgtccaacta aggagatcgc tatgctggat
    93481 gaaataaaaa tgattgaatc tgttgcacca gatattatcg aagtgttgca agaacgctat
    93541 aaaattttac gaaatatcta ttggatgcag ccgattggac gtcgaagttt atcggaaagt
    93601 atggggatca cagaacgagt attgcgaaca gaaacagatc ttttgaaaaa tctgaatttg
    93661 atcgacacct caaaaagcgg tatgacgctg acaactaagg gcgaagaagt ttatcaaagc
    93721 cttgaaaact tcatggatca gcttttaggt acgcatcaaa ccgaacaaca gttggcagaa
    93781 tattttggta accaacgctg tatcgttgtt tcaggaaaca gcgaagagca gaccaaagtg
    93841 gctgatgcat tcggcgaagc gctgagcgaa gccctagacc gactacttcc agaaggcgag
    93901 aatatcatcg ctgtgatggg aggaactact atggctgtgg tagccgaaca attgtctaat
    93961 ctggaaaata agaaacggca taacctgttt gtccctgcaa gaggcgggat tggtgaagcg
    94021 ataactgtac aggcaaattc tgtcagtgca agaatggctg ctaaagcaaa cggtaaccac
    94081 cgtgcacttt atgttccgga acaattaagt ctggcaactt acaattcttt actcaatgag
    94141 ccatctatcc aagaagtctt aaacttgatt agtgaagcga attgtgttat tcatagtatt
    94201 gggcgtgcat tacacatggc agcacgtcgt aagatgactg aaaaagaatt agtcatgctg
    94261 aaacaagcaa atgctgttgc ggaatctttt ggctactttt tcaatgaaaa aggtgaagtc
    94321 gtttataagg tccctagaat cggcatagaa ttgcaagatt tggaaaaagt cccgatcatc
    94381 atggcaatcg cgggcggaaa atcaaaagct aaagcaattc gagcttatat gaaaaatgca
    94441 ccaaaacaaa cgtggctcat cactgatgaa gctgctgcaa atgagatttt aaaaggggta
    94501 accctttaaa ataaatattt ttttgatttt cataaggagg aaatcttaaa tgacagttaa
    94561 agtaggtatt aatggttttg gacgtattgg acgtctagca ttccgtcgta tccaagatgt
    94621 agatggaatc gaagtagtag caatcaacga cttgacagat gctaaaatgt tggcacactt
    94681 gttaaaatac gacacaactc aaggacgttt caacggaaca gttgaagttc atgaaggttc
    94741 attcaacgta aacggaaaag aagttaaagt attagctaac cgcaacccag aagaattacc
    94801 atggggcgaa ctaggcgtag atatcgttct agaatgtact ggtttcttca cttctaaatc
    94861 agcagctgaa aaacatttaa cagctggtgc taaacgcgtt gttatctctg ctcctggcgg
    94921 aaacgatgtt ccaacaatcg tttataacac aaaccacgaa acattaactg gtaaagaaac
    94981 agttatctca ggtgcttcat gtactactaa ctgtttagct cctatggcta aaacattgaa
    95041 cgacaaattt ggtgttgttg aaggattaat gacaactatc cacgcttaca caggtgacca
    95101 aatgactcta gacggacctc atcctaaagg tgacttccgc cgtgcacgcg ctgctgctgc
    95161 aaacatcgtt cctaactcaa caggtgctgc taaagctatc ggtttagtaa ttcctgaatt
    95221 gaacggtaaa ttagacggag ctgctcaacg tgttcctgta ccaacaggtt cattaacaga
    95281 attagtaaca gttcttgaaa aagaagtaac tgttgacgaa atcaatgcag caatgaaaga
    95341 agcttcaaac gaatcttacg gatacaacac agacgaaatc gtttcttcag atatcgttgg
    95401 tatgacttac ggttcattat ttgatgctac acaaactaaa gtaatgacag ttggcgacaa
    95461 acaattagtt aaaactgttg cttggtacga caacgaaatg tcatacactg cacaattagt
    95521 acgtacttta gaatacttcg ctaacttata agatagacaa acgtacaagt gtaaattata
    95581 gacatgtaca tttaaaagcg gggaagcaat cgcgcttctt ccgctttttt tgataataag
    95641 tttattcagg aggaaataaa atggctaaga aaacagtgaa agatatcgat ttaaaagaca
    95701 aaaaagttct tgtccgtgtt gacttcaacg ttcctttgaa agacggcgtg atcactgacg
    95761 acactcgtat caaagcagca ttgccaacaa tcaactacgt tctagaacaa ggcggaaaag
    95821 caatcctttt ctctcacctt ggacgtgtaa aaacagaaga agataaagaa ggaaaatctt
    95881 tagctccagt tgcaaaacgt ctaggcgaat tattaggtaa agaagtaaca ttcgtacctg
    95941 aaactcgcgg agaacaatta gaagaagcaa tccgcaacat gaatgacggc gacgttgtcg
    96001 tattcgaaaa tacacgattt gaagatattg acggtaaaaa agaaagcaaa aatgatacag
    96061 aactaggtaa atactgggct tcattaggcg atgtatttgt taacgatgct ttcggtacag
    96121 ctcaccgtgc acatgcttct aacgtaggta tcgcttcaac tggtatccca acagttgctg
    96181 gattcttgat ggaaaaagaa atcaagttca tcggtgaagc agtagaagaa ccaaaacgac
    96241 caatgattgc aatccttggt ggcgcaaaag tttctgataa aatcggcgta atcgaaaact
    96301 tgattcctaa agcagataaa atcttgatcg gtggcggaat gacttacaca ttctacgaag
    96361 caaaaggaat caagatcggt aactctctag tagaagctga taaagtggaa ctagcaaaag
    96421 aattaatcga aaaagcaggc gacaaacttg tcttgccaat cgacaatgtc tgtgcaccag
    96481 aattttcaaa tgatgttgaa acacaagtaa tcgaaggaga cattcctgat ggtttgatgg
    96541 ctttagacat cggcccagca tcagtaaaat tatttgctga tacattacaa ggtgcaaaaa
    96601 cagttgtttg gaacggacct atgggtgtat ttgaaatgag taactttgct aaaggtacaa
    96661 tcggtgtttg tgaagcaatc gctaacttag aaggcgcaac aacaatcatc ggtggcggag
    96721 actcagccgc agcagcagaa caattaggat ttgctgacaa attcacacac atctcaacag
    96781 gtggcggcgc aagcttggaa ttgcttgaag gtaaagaatt accaggacta gcagcaatca
    96841 acgataaata aacgaccaag tttgctcaat tctgacgagt aatcgaacaa aaggtgaagg
    96901 gagttttcat gactccctag ccatttttca ataaattaag gagtgtgttc ctcaatgcgt
    96961 aaacctatta tcgcaggtaa ctggaaaatg aacaaaactg catcagaagc aaaagaattt
    97021 gctgaagcag taaaaaacaa aatcccttca aatgacaaag ttgattcagt catcggatct
    97081 cctgcattat tcttacaaga attaatgaca tcagctgaag gtacagaact aaaaatctca
    97141 gcacaaaact gctactggga aaactcaggt gcgttcactg gtgaaacttc accagcagct
    97201 cttgctgatc taggtgttca ttatgtgatc atcggacatt cagaacgtcg tgaatatttc
    97261 catgaaacag acgaagacat caataaaaaa gcgaaagcta tctttgcaaa tggtatgaca
    97321 ccaatcctat gctgtggcga atctttagaa acctatgaag caggcaaaac tgctgaatgg
    97381 atcgaaggac aaattacagc tggtttagct gatctttcag ctgaacaggt gtcaaacatg
    97441 gttattgctt atgaaccaat ctgggcaatc ggtactggta aatcagctga cgcacaaatc
    97501 gctgacgaaa tttgtggagt tgtacgtcaa acagttgaaa aactttatgg aaaagaagta
    97561 tcagaagcag ttcgtatcca atacggcggt tctgtaaaac cagaaaatat tgctgaatac
    97621 atggcaaaag aaaatgttga cggtgcttta gtcggtggcg caagcttgca agcagattca
    97681 ttcttgtcat tgttagacgc tgtaaaataa ttgttgaaaa tttgcgaaaa atgcaagaaa
    97741 tgtttgcact aatgagcaaa attaactaaa atcgtatatg agggaaatcc cttaggaaaa
    97801 aacaaactca aaggagagac aaaacatgtc aattattact gatgtttacg ctcgcgagat
    97861 cttagactca cgtggtaacc caacaatcga agtagaagta tacacagaaa gcggagcttt
    97921 tggccgcgga atggttcctt caggtgcttc aactggtgaa tacgaagcag ttgaattacg
    97981 tgacggagac aaagctcgtt atggcggtaa aggtgtaact aaagctgtcg acaacgtaaa
    98041 caacatcatt gctgaagcaa tcattggcta cgatgttcgt gaccaaatgg ctatcgacaa
    98101 agctatgatc gctttagacg gaactcctaa caaaggtaaa ttaggtgcga acgctatttt
    98161 aggtgtttct atcgctgttg cacgtgcagc tgctgactac ctagaagtac ctttatacca
    98221 ctacctaggc ggattcaaca caaaagtatt gccaacacca atgatgaaca tcatcaacgg
    98281 cggatcacat gctgataact caatcgactt ccaagaattc atgatcatgc ctgttggcgc
    98341 tccaacattc aaagaagctc tacgtatggg tgctgaagta ttccacgcat tagcttcaat
    98401 cttgaaagct cgcggattag caacttctgt tggtgacgaa ggtggatttg ctccaaacct
    98461 tggttcaaac gaagaaggtt ttgaagtaat catcgaagca atcgaaaaag ctggctatgt
    98521 acctggtaaa gacgttgttc ttgctatgga tgctgcttct tcagaattct acgacaaaga
    98581 aaaaggtgtt tacgtactag ctgattcagg cgaaggcgaa aaaacaactg acgaaatgat
    98641 caaattctac gaagaattag tttctaaata tccaatcatc tcaatcgaag acggattaga
    98701 cgaaaacgac tgggacggat tcaagaaatt aactgacgta ttaggcgaca aagttcaatt
    98761 agttggtgac gacttgttcg taacaaacac tcaaaaatta tctgaaggta tcgaaaaagg
    98821 aattgctaac tcaatcctta tcaaagtgaa ccaaatcggt acattaacag aaactttcga
    98881 agctatcgaa atggctaaag aagctggcta cacagcagtt gtatctcacc gttctggtga
    98941 aacagaagat tcaacaatct ctgatatcgc tgttgcaaca aacgctggcc aaatcaaaac
    99001 tggttctcta tcacgtactg accgtattgc taaatacaac caattactac gtatcgaaga
    99061 ccaacttggt gaagttgcag aatacaaagg tttgaaatct ttctacaact taaaaaacaa
    99121 ataattcttt tctaatgaag atacatgatc gactattgaa agatagtcga gtatgatcac
    99181 ttagttaagt aatcgaactc tctacttgct gaaatatcag caggtagaga gtttttttgc
    99241 aactagcttc tgtatatgat gtttacaaag aatggtacaa gaaaagatca tccttgaaaa
    99301 aggaaagcta acaataacta gcatcatata agagctttta aggatagaac agtagaatag
    99361 gaatctatga gcaagtcctc tcgtataaat aaaataggag ggaagtagca gcatattttt
    99421 cataaagtgg ctctctttct tcatttttac tttggttgct cctatttgaa aattcgagca
    99481 cactcaaata caataaaaag aaatggcaag ggagaggatt agatgaaaaa agaagaaaaa
    99541 atcgcgattt tacaagagat catccgaatt aaatcagtga atggaaacga aggtgaagta
    99601 gcagcctatt tgaataagct tttggcaaag catgacataa caggagagat tgtttcttac
    99661 agagatggta gagataattt gattgctcgt taccaaaagg gccaatcagg aaaagtgtta
    99721 ggcctatctg ggcatatgga tgtcgtggcg gctggtgatg aatcgtcttg gacctatgca
    99781 ccctttgcag cagaaatcca tgggaaccgt ttgtacggac gtggtgctac agatatgaag
    99841 agtggcttgg cagcaatggt gattgccatg atcgaactga aagagtcagg aaaaccattt
    99901 aacggaacag tcaaattatt agccactgtc ggagaagaag tgggtgaact aggtggggaa
    99961 cagctcacga aagcaggcta tgtagatgac ttagatgcct tgatcatcgg agagccaacc
   100021 aattacagtt tgatgtatac gcacatggga tcaatcaact atacagtcac ctcgcacgga
   100081 aaagaagcgc atagctctat gccagaccaa ggttataatg caatcaatca cctaaatgaa
   100141 ttcattacga aagcaaatgc tgaaatgaat cacctcgctg aaacaatcga gaatcctgtc
   100201 ctaggaaaaa caatccataa tgttacattg atcagtggcg ggaatcaagt caacagcatc
   100261 ccaagccatg cgcagctcca agggaacatt cgatcgattc cagaataccc aaatgataaa
   100321 atcattgcat tgctgcaatc aatcgtcaat gaattgaatc aagagacaga ctatcatttg
   100381 gaattgatga tcgattacaa caaaatacct gtcaaagctg atccagattc tcctttgatt
   100441 cattgcattc agcaacaatt cagccagcca ttacctttag ttggagcggc agcaacaacg
   100501 gatgcagccg aatttacgaa agctaaccat tccttcgact ttgtcgtctt tgggcctggt
   100561 gtcgttactt tgcctcatca agtagatgag tatgttgaaa tcgataatta tttggatatg
   100621 atcgaaaaat atcaaggaat tattttatcc tacttagcgt aagatttttt taataaatga
   100681 aaaaacagag ccagattagc attattt
//
LOCUS       DAFENC010000006        96492 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.006, whole genome shotgun sequence.
ACCESSION   DAFENC010000006
VERSION     DAFENC010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 96492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 96492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..96492
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.006"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            154..1212
                     /locus_tag="LP493_000556"
     CDS             154..1212
                     /locus_tag="LP493_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBL2132728.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            1216..2250
                     /locus_tag="LP493_000557"
     CDS             1216..2250
                     /locus_tag="LP493_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HBL2132729.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYYIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(2352..3068)
                     /locus_tag="LP493_000558"
     CDS             complement(2352..3068)
                     /locus_tag="LP493_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBL2132730.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(3037..3822)
                     /locus_tag="LP493_000559"
     CDS             complement(3037..3822)
                     /locus_tag="LP493_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HBL2132731.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(3813..4562)
                     /locus_tag="LP493_000560"
     CDS             complement(3813..4562)
                     /locus_tag="LP493_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBL2132732.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            4860..5384
                     /locus_tag="LP493_000561"
     CDS             4860..5384
                     /locus_tag="LP493_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HBL2132733.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            5400..6899
                     /locus_tag="LP493_000562"
     CDS             5400..6899
                     /locus_tag="LP493_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HBL2132734.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(6987..7589)
                     /locus_tag="LP493_000563"
     CDS             complement(6987..7589)
                     /locus_tag="LP493_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBL2132735.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            7693..8649
                     /locus_tag="LP493_000564"
     CDS             7693..8649
                     /locus_tag="LP493_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HBL2132736.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(8954..9910)
                     /locus_tag="LP493_000565"
     CDS             complement(8954..9910)
                     /locus_tag="LP493_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL2132737.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            10084..10644
                     /locus_tag="LP493_000566"
     CDS             10084..10644
                     /locus_tag="LP493_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132738.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            10637..11461
                     /locus_tag="LP493_000567"
     CDS             10637..11461
                     /locus_tag="LP493_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBL2132739.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            11471..12088
                     /locus_tag="LP493_000568"
     CDS             11471..12088
                     /locus_tag="LP493_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBL2132740.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            12106..12789
                     /locus_tag="LP493_000569"
     CDS             12106..12789
                     /locus_tag="LP493_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBL2132741.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            13472..14755
                     /locus_tag="LP493_000570"
     CDS             13472..14755
                     /locus_tag="LP493_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL2132742.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            14771..15658
                     /locus_tag="LP493_000571"
     CDS             14771..15658
                     /locus_tag="LP493_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2132743.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            15675..16511
                     /locus_tag="LP493_000572"
     CDS             15675..16511
                     /locus_tag="LP493_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL2132744.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            16514..17137
                     /locus_tag="LP493_000573"
     CDS             16514..17137
                     /locus_tag="LP493_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132745.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            17134..18426
                     /locus_tag="LP493_000574"
     CDS             17134..18426
                     /locus_tag="LP493_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL2132746.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      18785..18882
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            18998..19579
                     /locus_tag="LP493_000575"
     CDS             18998..19579
                     /locus_tag="LP493_000575"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBL2132747.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            19582..20889
                     /locus_tag="LP493_000576"
     CDS             19582..20889
                     /locus_tag="LP493_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBL2132748.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            21305..21793
                     /gene="purE"
                     /locus_tag="LP493_000577"
     CDS             21305..21793
                     /gene="purE"
                     /locus_tag="LP493_000577"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HBL2132749.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            21786..22910
                     /gene="purK"
                     /locus_tag="LP493_000578"
     CDS             21786..22910
                     /gene="purK"
                     /locus_tag="LP493_000578"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HBL2132750.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            22923..24218
                     /gene="purB"
                     /locus_tag="LP493_000579"
     CDS             22923..24218
                     /gene="purB"
                     /locus_tag="LP493_000579"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HBL2132751.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(24340..25728)
                     /gene="ltrA"
                     /locus_tag="LP493_000580"
     CDS             complement(24340..25728)
                     /gene="ltrA"
                     /locus_tag="LP493_000580"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBL2132752.1"
                     /translation="MRRPQKTRKLGYHQRASVEHEGYDEVRSTSCGEQRKQDGVENLF
                     GRILDRNNLNQAYLQVVRNKGAAGADGMTVDQLLPYLKEHREELLSNLRQGNYKPQPV
                     LRVEIPKPNGGVRKLGIPTVIDRMLQQAINQVLQPLFEPEFSDNSYGFRPNRSAHDAV
                     KKAKSYYEQGYRYVVDIDMKAYFDTVNHDKLMYFIERKVKDKQVLKLIRQYLMSGVME
                     NGLITTTEEGTPQGGNLSPLLSNIYLNEFDQVLENLGHKFVRYADDCNIYVRSKRAGQ
                     RVMKKSIQFLEEQLKLTVNREKSAVGSPLKRKFLGFCILPTKKGIKIRPHAKAKQRVK
                     SKLKQLTKRNRGRSIQLILKEIKQLMTGWINYYGIGEMKEFMRELNGWLKRRIRQYIW
                     KQWKNPRTKRKNLIRLGIDKAKAYEWSNTRKGIWSVSKSHILHRSLTDKELARQGYED
                     ISLKYQFVHSTY"
     gene            complement(26297..26674)
                     /locus_tag="LP493_000581"
     CDS             complement(26297..26674)
                     /locus_tag="LP493_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132753.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            26930..27658
                     /locus_tag="LP493_000582"
     CDS             26930..27658
                     /locus_tag="LP493_000582"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBL2132754.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            27658..27912
                     /gene="purS"
                     /locus_tag="LP493_000583"
     CDS             27658..27912
                     /gene="purS"
                     /locus_tag="LP493_000583"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HBL2132755.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            27914..28585
                     /gene="purQ"
                     /locus_tag="LP493_000584"
     CDS             27914..28585
                     /gene="purQ"
                     /locus_tag="LP493_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HBL2132756.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            28586..30808
                     /gene="purL"
                     /locus_tag="LP493_000585"
     CDS             28586..30808
                     /gene="purL"
                     /locus_tag="LP493_000585"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HBL2132757.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            30793..32232
                     /locus_tag="LP493_000586"
     CDS             30793..32232
                     /locus_tag="LP493_000586"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HBL2132758.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            32255..33307
                     /locus_tag="LP493_000587"
     CDS             32255..33307
                     /locus_tag="LP493_000587"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBL2132759.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVQESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            33304..33882
                     /gene="purN"
                     /locus_tag="LP493_000588"
     CDS             33304..33882
                     /gene="purN"
                     /locus_tag="LP493_000588"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HBL2132760.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            33879..35414
                     /gene="purH"
                     /locus_tag="LP493_000589"
     CDS             33879..35414
                     /gene="purH"
                     /locus_tag="LP493_000589"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HBL2132761.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            35430..36704
                     /gene="purD"
                     /locus_tag="LP493_000590"
     CDS             35430..36704
                     /gene="purD"
                     /locus_tag="LP493_000590"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HBL2132762.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            36826..37740
                     /locus_tag="LP493_000591"
     CDS             36826..37740
                     /locus_tag="LP493_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBL2132763.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(37873..39438)
                     /locus_tag="LP493_000592"
     CDS             complement(37873..39438)
                     /locus_tag="LP493_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBL2132764.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(39431..40882)
                     /locus_tag="LP493_000593"
     CDS             complement(39431..40882)
                     /locus_tag="LP493_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBL2132765.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(40896..41912)
                     /locus_tag="LP493_000594"
     CDS             complement(40896..41912)
                     /locus_tag="LP493_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL2132766.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            42132..43220
                     /locus_tag="LP493_000595"
     CDS             42132..43220
                     /locus_tag="LP493_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HBL2132767.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            43274..44800
                     /locus_tag="LP493_000596"
     CDS             43274..44800
                     /locus_tag="LP493_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBL2132768.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            44802..46007
                     /locus_tag="LP493_000597"
     CDS             44802..46007
                     /locus_tag="LP493_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2132769.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            46264..47241
                     /gene="guaC"
                     /locus_tag="LP493_000598"
     CDS             46264..47241
                     /gene="guaC"
                     /locus_tag="LP493_000598"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HBL2132770.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            47505..48929
                     /locus_tag="LP493_000599"
     CDS             47505..48929
                     /locus_tag="LP493_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBL2132771.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            49390..50499
                     /gene="pdhA"
                     /locus_tag="LP493_000600"
     CDS             49390..50499
                     /gene="pdhA"
                     /locus_tag="LP493_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HBL2132772.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            50502..51479
                     /locus_tag="LP493_000601"
     CDS             50502..51479
                     /locus_tag="LP493_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HBL2132773.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            51504..53147
                     /locus_tag="LP493_000602"
     CDS             51504..53147
                     /locus_tag="LP493_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HBL2132774.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            53155..54561
                     /gene="lpdA"
                     /locus_tag="LP493_000603"
     CDS             53155..54561
                     /gene="lpdA"
                     /locus_tag="LP493_000603"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBL2132775.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            54723..54998
                     /locus_tag="LP493_000604"
     CDS             54723..54998
                     /locus_tag="LP493_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HBL2132776.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            55004..55771
                     /locus_tag="LP493_000605"
     CDS             55004..55771
                     /locus_tag="LP493_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HBL2132777.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            55939..57768
                     /gene="typA"
                     /locus_tag="LP493_000606"
     CDS             55939..57768
                     /gene="typA"
                     /locus_tag="LP493_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HBL2132778.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            58029..59801
                     /gene="recQ"
                     /locus_tag="LP493_000607"
     CDS             58029..59801
                     /gene="recQ"
                     /locus_tag="LP493_000607"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HBL2132779.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            59915..60217
                     /locus_tag="LP493_000608"
     CDS             59915..60217
                     /locus_tag="LP493_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HBL2132780.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            60220..61383
                     /locus_tag="LP493_000609"
     CDS             60220..61383
                     /locus_tag="LP493_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBL2132781.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            61409..64837
                     /locus_tag="LP493_000610"
     CDS             61409..64837
                     /locus_tag="LP493_000610"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HBL2132782.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            64858..65982
                     /locus_tag="LP493_000611"
     CDS             64858..65982
                     /locus_tag="LP493_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132783.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            65972..66409
                     /locus_tag="LP493_000612"
     CDS             65972..66409
                     /locus_tag="LP493_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBL2132784.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            66393..66731
                     /locus_tag="LP493_000613"
     CDS             66393..66731
                     /locus_tag="LP493_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HBL2132785.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            66850..67410
                     /gene="rsmD"
                     /locus_tag="LP493_000614"
     CDS             66850..67410
                     /gene="rsmD"
                     /locus_tag="LP493_000614"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HBL2132786.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            67407..67898
                     /gene="coaD"
                     /locus_tag="LP493_000615"
     CDS             67407..67898
                     /gene="coaD"
                     /locus_tag="LP493_000615"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HBL2132787.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            67888..68931
                     /locus_tag="LP493_000616"
     CDS             67888..68931
                     /locus_tag="LP493_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HBL2132788.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            69090..69818
                     /locus_tag="LP493_000617"
     CDS             69090..69818
                     /locus_tag="LP493_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HBL2132789.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            69934..70179
                     /locus_tag="LP493_000618"
     CDS             69934..70179
                     /locus_tag="LP493_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBL2132790.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            70176..70394
                     /locus_tag="LP493_000619"
     CDS             70176..70394
                     /locus_tag="LP493_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HBL2132791.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            70530..71069
                     /locus_tag="LP493_000620"
     CDS             70530..71069
                     /locus_tag="LP493_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HBL2132792.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            71062..73335
                     /locus_tag="LP493_000621"
     CDS             71062..73335
                     /locus_tag="LP493_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HBL2132793.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            73373..74419
                     /gene="holA"
                     /locus_tag="LP493_000622"
     CDS             73373..74419
                     /gene="holA"
                     /locus_tag="LP493_000622"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HBL2132794.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(74508..74762)
                     /locus_tag="LP493_000623"
     CDS             complement(74508..74762)
                     /locus_tag="LP493_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HBL2132795.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(75162..75431)
                     /locus_tag="LP493_000624"
     CDS             complement(75162..75431)
                     /locus_tag="LP493_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132796.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(75901..76356)
                     /locus_tag="LP493_000625"
     CDS             complement(75901..76356)
                     /locus_tag="LP493_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HBL2132797.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(76494..78422)
                     /locus_tag="LP493_000626"
     CDS             complement(76494..78422)
                     /locus_tag="LP493_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBL2132798.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(78619..79452)
                     /locus_tag="LP493_000627"
     CDS             complement(78619..79452)
                     /locus_tag="LP493_000627"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBL2132799.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(79644..80348)
                     /locus_tag="LP493_000628"
     CDS             complement(79644..80348)
                     /locus_tag="LP493_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBL2132800.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(80371..80997)
                     /locus_tag="LP493_000629"
     CDS             complement(80371..80997)
                     /locus_tag="LP493_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBL2132801.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            81323..83698
                     /locus_tag="LP493_000630"
     CDS             81323..83698
                     /locus_tag="LP493_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HBL2132802.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(83722..84213)
                     /locus_tag="LP493_000631"
     CDS             complement(83722..84213)
                     /locus_tag="LP493_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HBL2132803.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            84400..85320
                     /locus_tag="LP493_000632"
     CDS             84400..85320
                     /locus_tag="LP493_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL2132804.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            85474..85818
                     /locus_tag="LP493_000633"
     CDS             85474..85818
                     /locus_tag="LP493_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HBL2132805.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(86008..86508)
                     /locus_tag="LP493_000634"
     CDS             complement(86008..86508)
                     /locus_tag="LP493_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2132806.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            87036..87119
                     /locus_tag="LP493_000635"
     tRNA            87036..87119
                     /locus_tag="LP493_000635"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:87070..87072,aa:Leu,seq:cag)
     gene            complement(87443..88081)
                     /locus_tag="LP493_000636"
     CDS             complement(87443..88081)
                     /locus_tag="LP493_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL2132807.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPV
                     QAEQPVVQETVQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTAT
                     NGRYIGRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            88416..88850
                     /locus_tag="LP493_000637"
     CDS             88416..88850
                     /locus_tag="LP493_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBL2132808.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            88873..89193
                     /locus_tag="LP493_000638"
     CDS             88873..89193
                     /locus_tag="LP493_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132809.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            89334..89525
                     /locus_tag="LP493_000639"
     CDS             89334..89525
                     /locus_tag="LP493_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132810.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(89596..89853)
                     /locus_tag="LP493_000640"
     CDS             complement(89596..89853)
                     /locus_tag="LP493_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HBL2132811.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            90011..90274
                     /locus_tag="LP493_000641"
     CDS             90011..90274
                     /locus_tag="LP493_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132812.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            90298..90486
                     /locus_tag="LP493_000642"
     CDS             90298..90486
                     /locus_tag="LP493_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132813.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(90569..90754)
                     /locus_tag="LP493_000643"
     CDS             complement(90569..90754)
                     /locus_tag="LP493_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132814.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            90969..91340
                     /locus_tag="LP493_000644"
     CDS             90969..91340
                     /locus_tag="LP493_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBL2132815.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(91490..91562)
                     /locus_tag="LP493_000645"
     tRNA            complement(91490..91562)
                     /locus_tag="LP493_000645"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(91527..91529),aa:Gln,seq:ctg)
     gene            complement(91608..92036)
                     /locus_tag="LP493_000646"
     CDS             complement(91608..92036)
                     /locus_tag="LP493_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132816.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(92096..92854)
                     /locus_tag="LP493_000647"
     CDS             complement(92096..92854)
                     /locus_tag="LP493_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HBL2132817.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            93149..93346
                     /locus_tag="LP493_000648"
     CDS             93149..93346
                     /locus_tag="LP493_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132818.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            93452..93934
                     /locus_tag="LP493_000649"
     CDS             93452..93934
                     /locus_tag="LP493_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132819.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(93992..94588)
                     /locus_tag="LP493_000650"
     CDS             complement(93992..94588)
                     /locus_tag="LP493_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBL2132820.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAEEKEYMNDADRFRVFG"
     gene            94975..96441
                     /locus_tag="LP493_000651"
     CDS             94975..96441
                     /locus_tag="LP493_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBL2132821.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT        31119 a        16707 c        20493 g        28173 t
ORIGIN      
        1 taaaaatcac tttacataag tttcaaaagt ttctttaatt tcctattgtt caataagtaa
       61 caatgtaaag ataaaattaa aaatgttaat acgtattagc aaaataaaag ctttttttat
      121 tgtgaataaa tgaacataat taggaggaga aagatgaact tatttgacat ttttcgatcg
      181 actttgacag atatgtcgat tgtcagtgca atcacttcaa cagtttttat tatattatta
      241 gggtttgttt gtagaaaaaa ggggattttt tctgaatctg ttggaaaaat tctatcgaaa
      301 gtcgtcttaa cagtggcttt gccagcactg gcatttcgag ctttcatgca agatatcaat
      361 acagaattac tgatgcaagg aatcaatgtc ttgatttggg gattagttat ttatattatt
      421 cttattctag tttcaaaacc ttttttctta agctataaag gggataagca aacaacgttg
      481 cgtgtcctga cgatctttgg ttctacgacc tttttcggaa cgcctatcgt cagtgcgatt
      541 tatggtcctg tcggcgtgat gtattcctca attttcaata ttggctaccg aatctttttg
      601 tattcttatg gatacataaa aatgagtggc ttgaagatgg aagctaaaaa tatcaaagcg
      661 atgttcgtca atccaatcat tatcgctact tttgccggcc ttttcatttg gctgttccaa
      721 gggtatctgc cacaagtgtc agttacaggt gcagaaggag agataagcca agtagcgttt
      781 ttgcgaattg accagactgc accgtggcta tttcagccga tggattattt agctggttta
      841 agttcaccat tggcgtggct agcaatcggc gcaacattag gtgaagtaag cttcaaaaaa
      901 gctgcatctg aaaaaacttc atggtattac agtctagtca aagtggtatt tgtacctgca
      961 ttgaatatcg tgattctagc agttttgacg gcaacgaata ttctaccagt caattttgaa
     1021 gcactggcaa caatcgttat catgatggct acaccagctg caacagtggc agcagcctat
     1081 gctatcagtt ttgataggga ggcactttta gcctccaatg catccttact gtcaactatt
     1141 tttgctgtgg tactgacacc tgtatggatc gttgtattac aaatgattca tggcataggt
     1201 ttattttcat aagaaatgga ggaagaaagt atgagaatcg catgttacgg tgttcgtccg
     1261 aacgagatag atttttttga aaaattgaat atttaccatt atgatctcag tctttatgaa
     1321 gaactgttga cacatgacaa tatcgtgtca gcaaaggacc atgatgctgt attgttgagg
     1381 ggaaattgta tagcagatga gaccaatctt gcaaaaatgc aggaatatgg gattcgttat
     1441 gtttttacac ggactgtggg agtcaatcat atcgatctac aagcggcagc tgattttggt
     1501 atgacagtag cccgtgtacc atcgtattcg ccaaatgcga tagcagagtt atctttgact
     1561 tttgccatga tgcttttgag aaatactgcg tatacgacga tccgaacatc tttcaaagat
     1621 tttcgagtgg atgagcaaat gtttagtcgt gaaatcagaa attgcacagt agggatcata
     1681 ggaacaggca ggatagggtt gacggaagct gttttgttta agggactagg agccaaagtg
     1741 atcggctact atattcatca gacagaagct gctaaaaaag tattgacgtt ccactcgctt
     1801 gaagagttat tagccaaaag cgatattgtc agtattcatg tacctcatat cccaggtgaa
     1861 aacgatcaaa tgatcaatga aggattttta gctcaaatga aaaaaggtag catcttgatt
     1921 aatacagccc gtggagagct tcaagataat gaagctattt taagagcttt gaaaagcaat
     1981 catttagctg gttttgcaac cgatgttttt gcaaatgaaa cagaggtttt tttccgatcc
     2041 ttcaagccat gggagacgat tccagaccct gctatccagc aattagtaga aatgtaccct
     2101 agagttcttg taaccccgca tgtaggttca aatacagatg aggcattatc aaatatgatt
     2161 tcgacaagtt tcgagaactt tcgtgaaata atagaaactg gaaaaacgaa aaatgaggta
     2221 tctcttccta aagcccgtca attaagataa gaaaacatgg atattcgtca ataaaatgtt
     2281 taaaaatagt ccaagtaaac agttgttact tctgtatact tggactattt tgtatgggat
     2341 aattcgatga ctcaacagta atctgtgagc tttttccgcc cattctttgt caattcataa
     2401 caggttagcg gccggccgat ttccaaatat ttgattcttt cgttcaatat atcttgttct
     2461 actaaaaaat tcaaatattt cttgacggat atacgtgaca gtgagctttt ttgagccagt
     2521 tcttttgttg aaaaaatagt atcttctttt agaataaatg cacttatttt ttttaaagtc
     2581 agttttgaca gacctttagg caaatcgatg aatgatggta tttcgtgaat gggagtggtg
     2641 tggttgaata cttgatcgat caatttctga tcggcttttt cagtcgtttg gattgtctga
     2701 gagaaagcaa gatacttttc gatcgccagc tgaaaacgtt gcaaagtgaa cggtttgatc
     2761 aaataatcta aggcaccgta gcggatcaca ttctttatgg tttcgatatc atctgcagca
     2821 gtgatcaaaa tcactgggat atcatttcct tgctgtctaa gccaagataa aaaatggata
     2881 ccactttcgc caggcatgta tacatcaagc agcagcagat ctgcgttttt ttgtctgaaa
     2941 tatttttttc cttcttctac atttctgaaa ctttcgatta cgttcatatt agggatgctt
     3001 tccacaaaag tacgattcaa ttctgcaacc attggatcat cttcgattat caggacattt
     3061 gtcatcattt tgatcttcct tttttggtaa ttctagatag acgattgtac cgccatttgt
     3121 ttgtttggaa aattctaaaa atccaccgtg gcgtttgacg attgaatgga tgagattcaa
     3181 tccaaaccca cgattgattc ccttcgtcga aaaacctagc gtaaatattt tttctgagat
     3241 ttcttctgat atcccgacac cgtcatcgca gacggtcacg atgaatactt cagcttctgt
     3301 gtcatagttt aaatgaatcc ggacctgtcc gtttctttca tgtttttgta gcacggcttc
     3361 ttttgcatta tcaagtaagt tccctaacac ttgcaaaagt gaatggatgg agtcatccat
     3421 ctccatttta gggataaaag aatcgctttc taacagcatt tcaacagatt gttctttggc
     3481 ttcgtttatt ttgcctaata aaaaaccggc aattgcaggt actttgatca gacttgagac
     3541 ttggccaatc tcttttttat aattttgatt tagctgctgg ataaaatggg tgacttcttc
     3601 atacttcttc aaatcaatca aaccagaaat gacatgaagt ttattcatga attcatgggt
     3661 ttgagctctc atggagttta tatattgttt cgtcccccca agctcctcca ttaatttcat
     3721 tacttctgat cgatttcgta aagttgcgac tgctcctaaa aaacggtcat tgctaaaaag
     3781 aggtgtaacg ctagaaatag tttctatccc atttaaatac atggattgag tccgaacggt
     3841 cgtttgatgc tcaatcgtct ctttaaacaa aacgtcatat agattatcac tgattttttt
     3901 cctacttcga aatccaatag ctgctctgtt tggtagaaaa tgttttttgc aggtgtattg
     3961 atcaagagga tagttttatc agaagagatg gctaagattc cttcatctac ttcattttcg
     4021 ataatcgttt tttcacttaa ctgttctgct atttcttgtg gttcaagtcc aagcagtact
     4081 tttttcattt tttgggcaag aaaaacggcg cctatgatgc ctacgctaag tccaataatc
     4141 aatgaaaaaa caatcatttt ttgtccatct ttgacttgat tgtcaatcgt gttgtttgtt
     4201 aagccaacac aaactgcacc aataatctct tgatcataat aaatagggac gaaatagcgg
     4261 aagccgaacc ctaacattcc ttctttttca gagaaaaatt cttgtcctcc aatcactttt
     4321 ttcacatctt catgacttga gaaaggaaga ccgatgtaac ttgggtctgc gtgagaatat
     4381 cgaatgcctt cagggtccat gacaacgata aaatctaaat tcgatgcaat catgatttca
     4441 tttgttattc cttgaatcgc atgtgtcggg tcaccagtct gcagcttttt ttggatgagt
     4501 ttatcattgg caacgatttt agcaatgcta gagattttat ctgacacact agatcggttc
     4561 atcgaaagaa taaaattcct gatcaatatg gcagaaacaa tcaaagaaac gaatgtggag
     4621 aaacaaacga caaggatgat cgtgttctgg agctttaatg gttttttctt aaaaaaagga
     4681 aacataggct acctcgaaag aatttattgt gaaaatttta acatgaaaac aaaaatttaa
     4741 caaattgtca acgataaaca caaccttcct ataaaaaaca ccactgagtc ggtaaaagaa
     4801 gctatacaga attttcaaac attggtatga tagacgtaga aatggaagga ggcgtgtata
     4861 tgataggggg aatcgcactt gagacgattt attggtatac attgctgatt tgtgcaggat
     4921 tggcagtcct attgattatt tttggagatg tattcgattt tgatggcccg cttgatccga
     4981 tgcttattat cccttggtta actttcacaa gcttatttgg ttttctaggt gagcgtttaa
     5041 cagatcaatc atctttattt ttatttattg ctagtggagg catatcgata gtgttggtat
     5101 ttttgcttaa tttctatata ttgatgccga tgaaacatgc cgaatcaacg atgtcgtctt
     5161 ctgaaaaaac tctggaagga caagtagctg ttgtgatcac accgatccct gtacgaggta
     5221 tgggagaaat tcagttgaaa agtgttaccg gttccattag tcgtccagct tgtttttaca
     5281 gcccccaaga acagacagct gagcggggaa cgaaagtatt gatcattgag atcaaggaaa
     5341 gaatctgtta tgtcatgcct tatgaaagca tgataaaagc ttaaaggagc gtgtgttaaa
     5401 tggaaatacc agttgttttt atcgcgatcg caatcgcagc tttgatttta ctgatgttgc
     5461 tgatcgtctt tgtagcgaag taccagacag caaaaccgga tgaagcgttg atcatcagtg
     5521 gaagttattt aggaagcaaa aatgtgcaca ttgatgaaag caataacaaa atcaaaattg
     5581 tgcgtggagg tggcgcattc gtcttgccag tttttcaacg ttcgaatcgg atcagtctat
     5641 tatcgagtaa attggacgtc tccacccctg aagtgtatac ggaacaaggc gtaccggtga
     5701 tgtgtgatgg tacttcgatc atcaaaatcg gttcatctgt agaagagatt gctacagcag
     5761 cagaacagtt tttaggcaag acaagagaag aactggaaaa tgaagcaaga gaagtattag
     5821 aaggacactt gcgctcgatt cttggttcta tgactgtaga agaaatctat caaaatcgcg
     5881 ataagttcag tcaaagcgta caagaagtcg cttctgtaga ccttgcaaaa atggggttga
     5941 tcatcgtttc tttcactatc aaagaggtca gagacaaaaa cggttatctt gactctttag
     6001 ggaaaccaag aatcgcccaa gtcaaaagag atgcagatat agcagaagcg gaagctctaa
     6061 aagaaacgcg tatcaaaaaa gctcaagcag aaaaagaatc acaagcagct gaattacagc
     6121 gacaaacaga gatcgcagaa tcattaaaag aaaaagaact gaaattagca acctacaaac
     6181 aagaacaaga tgttgctaaa gcaaaagcag accaagccta caatttagaa agtgcccgag
     6241 cacaacaaca agtaatcgaa caggaaatgc agattaaaat cgtagaacgt caaaaacaaa
     6301 tcgaactgga agaaaaagaa atcacacgtc gtgaaaagca atatgattcg gaagtgaaga
     6361 aaaaagcaga tgccgatcgg tacgctaaag aacaagaagc acaagctcaa aaagtcaaag
     6421 aagtgactga agccgaagca gaacgattcc gtgtggaagc actggcagaa gcggaagcca
     6481 ataagacacg tttagctgga caagcagaag ccgaagcagc actagcaaaa ggaaaagcag
     6541 aagccgaagc aaaacaaaag atcgccaatg ccttcaagga atatggcgaa gcagctgtct
     6601 tgagtatggt tatcgatatg ctaccgcaat tgatgcgcga agcagcacag ccgctaggaa
     6661 atatcgaaaa aatctctgtt gtcgatacag gaagcagttc aggagaaacc agtggagcga
     6721 accgagtgac aaattatgcc acaaatttgc tttcttctac tcaagaaaca ctaaaagcga
     6781 caacaggact tgacttgaag gaaatcgtag agaatttgtc gacacgtggg actactagcc
     6841 aagtaaatat gtatgaagcg ccaaaagagg cagaacaaaa ctcgatgaag gaagaataaa
     6901 gtagtacact tcaccgttca atcaaaaatg gaggaagact ttttaaagtt cttctctcca
     6961 tttttttatt ttattgcaaa agaaaattag tcctcgctat ttttcttttg tttttggatc
     7021 ttagcttcta tctcttgtaa atttgttctt agcaatcgtt ctttcttttg gagttcgacc
     7081 aaatcttctg atagttcttc cttcttttct gtttcaggag gacgaagaaa gaaattgata
     7141 ccgattgcaa tgaatgtccc tataaaagta tctagtacac gttggatagc atacaaagcg
     7201 gattcgcctt gagggatgct caacgcaatc agcaacaacg tagctattgc ggaaatgata
     7261 ccggaattat tgttaatacc atctgacacg acgatcacaa taataactag aataggaagc
     7321 aagatcaatt ctaccaaaaa atcattgtga aaatagcttt tgacaaaaaa ataaatgata
     7381 gctaatgtac cacctaatgt attgccgatg atcctagact ttccaaaaga aacggttgta
     7441 gtcaagtcct gacgcaaaga aaaaacagca gataatgcag caatcatcgg gattcctcgt
     7501 tgagtcaaat gaaaaaacaa gatacataaa aaaacagcta aggcactttt gatcgtacgc
     7561 atacctagtc gaaaacggcc aaattgcata gagattctcc tttttggtct ttttactatc
     7621 atacctaaac ttttgtctga tagctagttt ttcattattc aagtataatt aaaataaaaa
     7681 agggggaagt aaatgcgtat aggaatgcga acagtcaaaa cagtgatcag tgtcttcttt
     7741 tcgatggtca cagcgggtag cttatcgctg ttgtattggc cagctgcagg gatcattgca
     7801 ttattaagtg taggaaatac caagcgctct acattgcgta cgggcatgaa tcgaatcgca
     7861 gcctttatat tagctacggc aacagcactg ttcagttttt ttgctgttgg gtatactatt
     7921 tttggcttca gtcttttttt attcctgttc atcccgcttg cctctcgctt caaattaacc
     7981 gaagggatag tagtaaattc ggttttggtc actcattatt tagtggagga aaacatgtct
     8041 tggcagctga tcggcaatga agcgggatta atggcgattg gattagtatt tgctttgctt
     8101 gcaaatgttt acatgccaga tcgtacgaag cagctgaagg aaaaccaaat acagatcgaa
     8161 aaagaatttc gaaatatttt gagacaaatg gcagaatttc ttttatcaga aaataaagaa
     8221 gatgtgcaga tcaaatgcga acatttactg acattcattc gcgaaagcca agaagatgcc
     8281 agagaacatc aagaaaacta ctggctcaga cagccgctat actacgaaac ttacttctct
     8341 atgagaagag cacaggccaa tgtgattaaa gacatgctgg aaaatctaga gagaatccag
     8401 caaccagctt attatggaaa acatatctat ggtttattga tttatactgc agaaacattt
     8461 tcagagtcaa atgatggcag acaaatttta acacgtattg aagaagttta tgtattgtat
     8521 cggcaaatgc ctctgccgac tagtcgccct gaattcgagg atcgagcaga attgttccag
     8581 tttttgcagt cttttaaaag ttttattgaa atcaaggcag aattctccca acaaaaaatc
     8641 caaaaataga ggttgtgaat tcagctaata ttcaggtcaa aaagctgatt tcacaacctc
     8701 ttctttaaac ggtgttctcc tgtcaactcc tcggtcacaa gtcacaatat tcaacaaaca
     8761 tgagaagctg ttttttgaaa ttgctccttg tgactcggag ctgaacggta ggctcacaac
     8821 ctctttctta aacggtgttc aaaagctttc ctctgcggta ataagtccag ccaaacgaaa
     8881 aataggagga gctatttttg tttggctgtt cttattactt gatgcagaac agctttttca
     8941 caacctttta aaattacata tttttccata gaacttgcat ttgatccaag atttcgatga
     9001 catcttttgt caagaagaga gagcgattgg gcaagtcacc ttcaatcatg tgtaccatat
     9061 tctttatttc gtaattcatt gcttcagatg tattcccgct ttcgatgaat tcctttgtac
     9121 catctgtaaa taagatctcc gcacgatcag cacgcgggta atcagcaatc gtcacataac
     9181 cgttctcaaa ggcaacgata ccgacttttg gcatttttgc ctgaaaagtc aagctgacag
     9241 cagcaagttc attttctttg ttacgcaaga tagtgacgga ttgttcgtcc acgcctgttt
     9301 caaaaggaac cattgtagag gcaactactt caggttgaga gctcaaaaag aaacgagcga
     9361 aagatacagc atacgtaccg atatccaaca gagctcctcc agctaattct ggattgaaga
     9421 accggttttt agggtctggt tctttgtaac tgccgaaagg tgcttggatc atttttaaag
     9481 cccccagttt tcctgtatcc attattgagc gtaactgctg ataaagtggc atgttgaaga
     9541 ttgtcatcgc ttctgctaag atcaaattct tttcttctgc taagcgcata gcgtcagcca
     9601 gttctttttt attcatcgtg atggcttttt cacatagaac gtgtttgcct gcttccaatg
     9661 ctgccaagat atggtcgata tgctgtctat ttggtacagc aatgtacacg atgtcgattt
     9721 cagcatcgtc taacatttct tgatagcttc cgtaagcttt tggaatattg taacggtgag
     9781 cgaagttttc cgctttttct gaagttctgg aagcaactgc tgttagttcg ctcgtctctt
     9841 gattgaagct ttcggcaaac tcatgtgcga tggtaccaag accaacgatt ccccattgat
     9901 attttttcat ctgaaaacgc tccttcatag ttggattgag tttcttgtct gtctattatt
     9961 ataacaaaaa tcacgaagaa taaagaggag aggacttgaa acattaaaaa aaatgaaagc
    10021 agcgatttaa gaggtgcttt ttgatcaaaa cttaagtaga atagttaaaa ggaggggata
    10081 aacgtgcatc aagtatatat tgatcttatt atgagtgtat tattagaaca gtttgaaact
    10141 gaaaaaaatt ttttagatga atacttgctg atcagtccag aacaatggca aaaatggaaa
    10201 gatggcgaga aaaatctgcc atctgaagcg atgcagaaag taaaaaatct tttcactgat
    10261 tatgaatgga tgctaacgca aaagattttg cgtcaaacga ttatttttcc cgaaaaacga
    10321 aacgttgccg ttgcagagta caagcaaatc aaaacacgca tcgcgcaaaa atggcttagc
    10381 agcaaagcag caaaagtcga gctgatccct ttgaaaaata atcagcaggc tggtagatac
    10441 cttgacttga aagtaagtat tcaatatgat gaatggggct atgatgatat tttgaatttt
    10501 cgtctgccag cagatgttca aaaacagatc gaaggagaaa aaatcgaact tctcgattgg
    10561 gtgaatgaaa atctggaaga aacttacgtt catgaggcga atggggaacg tgaagaacaa
    10621 cgaaaggatt tttcaagtga ataaattttt aggatttgga gcagttgtga ttatgatcgc
    10681 agcaatgggc tatgttattt ttagcgatga tgattcgcat gttcaagccg gcaatcaagc
    10741 agtcgaacga acaagcacca aaacaactgc tagtaaagaa aagaacagtc aaacaaccag
    10801 cagcaaggta aaggacaaag aaacaaaaga tcgtacgtcc aaacaattgc cagatgttaa
    10861 aacagacgat tggaagctag ttttggttgg tccagatcac aaattagaaa aagaaattga
    10921 tgagtctact caattggcat cattaagtaa cggatacttg atcgacaaac gcattgctcc
    10981 agaatatgaa gcatttgcca aggctgctga agcagctgga tttccattag tgatggtctc
    11041 agcttaccgg tctgtatcat cccaacaaca agttttcgaa caaaatgtcc aagatgtgat
    11101 gagtcgtcaa ggtgtatcag aagaggaggc gacaaagatt actaaagaaa cgattacgga
    11161 gccaggatac agcgaacacc acacaggtct ggcagtcgat gtcgtcgatc aaaactggta
    11221 caacagttat ccttctactg tattggatgc aagttacgga gatcagcctg gagctaaatg
    11281 gatcgcagat aatgctgcgc agtatggatt tatcgttcgt tatccaaaag gacacgaaga
    11341 tataactaag atcacatatg aaccttggca cttacgttat gtcggtaaag aaaacgctga
    11401 gtatatcacc aaacaccaat tgacgctaga agaatatctg aatgaattaa atgaaaagta
    11461 ggaattgatc atggcgaaaa aaaagtggaa aaagcaaaag cgcaagaata tccgttggcc
    11521 agcagtggtt gccggtgtag cagtgatact cttagccttt gttttttcct tgaagaatct
    11581 gtcttctcct tttactgata atcagcaaga aaatgaagcg caatcccatc agcaatttat
    11641 tgaacggctt gttccgcatg cccaagaact acaagatggt tatggagtgc ttcctagtat
    11701 cattttagga caagctatat tagaatcaaa ttggggaaaa agtaccttgg ctagcaaata
    11761 caataatctt ttcgggatca aggcttatgg ggatcagaag aaagtaagcc tggaaacaaa
    11821 ggaatttgtt aacgaagaat ggataactat ccaaggagac ttcaaagtgt atgattcatg
    11881 ggaacagtcc atggatgacc atacacaact gttcgtccaa ggagtagatt ggaatcctgc
    11941 gctgtatgaa aaagtgatta cggccaccaa ctatcaggaa gccgcacaag cattgcaaga
    12001 tgcaggttat gcgacagacc ccggttatgc gcaaaaaatc atccaggtca tcgagacgta
    12061 tcaattgaat cagtatgacc ggagatagca aaggagaagt ggctgatggc agaacaattt
    12121 acgccagaaa tcatgacgga attgagaaaa gatatcgtaa gagtaccgga aatcatttta
    12181 gaagcaagcg ggatcaagat atttggaaaa ttgatccgtt cgatcatctt tactacggat
    12241 attgcgatca tacgtaatac aaatgcgaat gcagtaattg ctgtgtatcc ttttacacct
    12301 catccagcga ttactaaaag cattattgag gcagctgaca ttccagtttt ctccggtgta
    12361 ggtggtggtt tgacacaagg tgctcgttct tcctacatga gcatgttcgc agaagcgcaa
    12421 ggttcgttag gggtcgtttt gaacggtcct acgcctttag agacagtaaa agaagtttgt
    12481 cgagtagttg atattccagt tatcagtacg gtaacgtcga aatatacaga aatagatgaa
    12541 aagttagcag ctggtatttc gattatcaat atcagtgcag gtaaagaaac tgcagaagca
    12601 gtacgccatt ttcgtaaaaa atatcctgaa cttcctatca ttgcgacagg tggtccaacg
    12661 gaagaaagta ttgctgagac cattcaagca ggagcaaatg ccatcacata tacgccacca
    12721 agtagcggag agctttttag tcgtaaaatg gaaaaatatc gggaaactga gaaaaagaat
    12781 catgaataac aggtgagaat caaaagacga ggaagagcag atagtggctc ttcctcgtct
    12841 tttgtactcc agtactattt gttcagaatt caaaaaaaag agaaattttt ttgttttttt
    12901 acctgtaatg tacataagaa gagttaaaac cttttgttat tattagcatt ctaacaaaaa
    12961 aatgtcttga tttattgaag cgctttctat agaatgaaaa acgaataaaa actaaaaaag
    13021 gcacccgaca atttagtagc agctaaattg tcggggcttg aaaagtcagc gggaactgac
    13081 caatcaagtt gccatagtca atgcttgtgc atcgacgtgt atattgtacc taatttcata
    13141 cagaattact agttattttt ctgtttttta gggaagagcg cacacgaaga agcatgctta
    13201 tttagctatg tcaaggatat tgggcagttg tctgatatcc ttttttcttt gcgtaattat
    13261 cctcccatca ttgaagcaag aagtgttttt agcgatgaaa gaagaatcag cactatctaa
    13321 tttttcttga aagtattgag ttgttcatcc taggcagaac gataaggcaa gtcttggttt
    13381 ttattcccct tgaaaaagat cgtttaataa atatgttctg tataaaaata cagtatattg
    13441 aaaaataaca atggaagtag aggtgcagag aatgaagaaa agaatgagaa tcatcttagc
    13501 tttaagtgtt atgttattct tcttgacggc ttgtgggcaa gaagatgaca aaaaaatcac
    13561 gctgaacatg gcttggtggg gttcgcaagt ccgacacgat gcaacagtaa aagtaatcga
    13621 gctttatgaa gaaaaaaatc cccatgtgac gatcgattat gaattttatg attatgaagg
    13681 atattacaca aaattaggta cactagcagc atcagatgat atctgggaca ttttccaact
    13741 gaacaatcaa tttcctcaat acatcaatca gattgaacca ttagatgaat atgtggagca
    13801 agggataatt gatatttcta atgcagatga atcctattta gcaacgacga cttacgacgg
    13861 gcaattagtt ggactgtcta acggggtgaa ttcgtttgcg attgcttaca ataaaaatat
    13921 atttgaacaa ttaaatatcc ctgaaccagc ttcaaattgg acatgggatg aatttgaaca
    13981 aatcagctat caaatcactg aagaattagg aatctatgct atttcaagat tcgaagattt
    14041 tatagctggc tgtattattc aaataccaca agttgagaaa ggattgaatt tttataatcg
    14101 ggaagatcta tctaacagct tgggatttga aaatccagac tatctaacag attttttcca
    14161 gctgcgtaaa aatctggtag acaaaggggc ccatccagaa ccaggtggtg gagctgcaag
    14221 tacgacggat ctgtcttttc aggcggttag ggatagagaa gcggcaatgg tgtttctatc
    14281 aagtaaccag ttgacagaaa tattgtcagg ggctcctgaa gatatggaga ttcagttgat
    14341 taatccacct cgcagaaaag cagatggaga atctggtatc cctttacgtt cttcgcaaat
    14401 gctgagtatg gcaaaaagct cagcccataa agaagaagct gctaagttta ttgatttctt
    14461 tcaaaacagt gaagaagcca atgaaatttt aaaaggagaa cgtggtgtac caatcatgtc
    14521 gaatattcga gaacagctcg ctcgtgcaga tgatgcaact ttgcaagcga catttgatta
    14581 tttagaaatg atttccgata tggacaacgg cgaagtgaat gtctttgata gtgctttgaa
    14641 tccggaaatt caagaccaat acaatctttt agttgaaaaa gtcatttatg aagaagtaac
    14701 agcagaagaa gcagcagaga gtctttatga gtttgcgtca aacattctag gatagcagca
    14761 ggaggaaggc atgaaaaaag aaaaactaaa acggttcttg gatcaagaca atgtggtcgg
    14821 ttacgtattt gcttctccat tcatcctagg atttctattg ataacagtga taccgatgat
    14881 cttgtcactt tattattcgt tcaccgatta tcgtttggga aatccagtct catggatcgg
    14941 cttggataat tatataaaga tgctgagtga tgcccgtttt ttgaactcca tccgagtcac
    15001 ttttctctat gtatttgcat ctgtacctgt gaaactgatc tttggtctat tgattgctta
    15061 tcttttaacg aggaatatca aaggaacgac tttctttcgt tctttgtatt atgtgcctag
    15121 tttgatcggt ggcagtattt ctatcgctct agtttggcgg gagttgtttt ctaaaaacgg
    15181 gttagtgaat attttcctgg aacgattagg cgcacctgcg ctttcctggt ttagcgatca
    15241 aaaactggtc atgatccctc ttgttttgat gtctgcttgg caattcggtt cggcaatgat
    15301 catctttgct gcaggtatca aagagatccc aggctcgtat tatgaagcgg cagagatcga
    15361 tggagcgaac aaatggcaga cgttttacaa gatcacgtta cctcttcttt cgccgatcat
    15421 tttgtataac ttggttatgc agacaatcgc ggcgtttatg acttttacgc aggcatttat
    15481 cattacccaa ggtggtccga atgatgccac gaacttttat gctctttatg tgtataacca
    15541 agctttttct tttaattcta tggggtatgc tagtgctatt tcgtggatca tgctgttgat
    15601 tatgggagct gtcacctttc tgattttcaa atcatcaaaa aaatgggtcg ttgtgtgaat
    15661 gagaggagga agaaatgaat aatacagtaa cgaaatggtt tcaatacggt tttattttgc
    15721 tattaggtct agtcatgatt tatccggtct tatggatgat cgcaggttct tttaaaacgg
    15781 atcaagagat tatgagtggt tcgctgaatt tgattccaga gacttttcaa tgggaaaatt
    15841 acgcaaaagg atgggcgggg tttgctggaa tttcattttt tactttcttt aggaattcgt
    15901 ttgtcatctc tgcagtttcg acgataggga cagttctgag ctcgacttgt attgcttacg
    15961 cattatcgag aatcgatttc aaaggaaaaa gattctggtt cgtcgtcatg ttagtaacga
    16021 tgatgattcc tgcacaagtg attttgattc cgcagtttat tatttacaat cggctgaatt
    16081 tggttgggac gtatgtgccg ctgattttac cacatttttt tggacaagca tttttcattt
    16141 accagatcat gcaattcatg gtcagcatcc ccaaagagtt agatgaatca gcgattattg
    16201 acggatgcag caagtatagt gtctttacca aaattatttt tcctttgctg aaaccttcga
    16261 tcatcacgac gatcatcatc cagttttatt ggaaatggga cgacttcatg ggaccattga
    16321 tttatttaaa caagccgaga tcttacacgg tatcgattgc catcaaatta tttgcagacg
    16381 ctggatctag tacgacttac gcgagtatgt ttgcgatgtc tacgttgtcg ctgctaccgg
    16441 tttttctgat tttcttattc ttcaataaat atcttgtcca ggggatcagt acaagcggtc
    16501 tgaagggctg aatatgaaaa agccaataga agagatgttt ctttacaagc tcaactacta
    16561 tgtctgtcgg atttttttaa ccagtcttat cagtaatgct cttttcgctt tagttctagg
    16621 atgtttgttc actttaggat tagtgctgtc tgctcgtgtt gtctatctga tttatttttt
    16681 gatgatgtat ccttcttatt atctatctgt ccattacttg gcagaaaaaa aggtatgttg
    16741 gaggaaagga aaaatcaaac ggatgtgttt catcattacg ttgtttcagc tgtttgtcat
    16801 tatttttgca gttgattggt atttattagt gggaaagatt ggagcttggt atctgattcc
    16861 ttttctattg tgtctgttgc tttttgtatc ccatagtttt tttagtacgc taattgatat
    16921 ctgcaaagaa gataaagcag atagtcttgt ttatttgatc aaaaggaata tctggctgtt
    16981 gtcaaaaaac gtcaaggggt ttctgtggta tttatgcctt ttgtatggac tgttctggtg
    17041 tatacagcat gattttttac tcactgcatt actgtatcca gggctgccat ttgtcacagt
    17101 attttgctta aaagaaaagg agaatgactt taaatgaaga aaaaatatgt acaagtcgga
    17161 cttggtggga gagcgcgttt tttttatgag gcaattgcct ctacgtatca tcaaacttgt
    17221 gaactagtcg gtttttgtga tgtatctcaa acaaggatgg attatgcaaa tcggatactt
    17281 gtgaacaagt atggacagaa aaaagtaaag acatgtatgc catcacaatt tgagcaacta
    17341 ctggatgacg tacggccggc tgaagtcatt attacgtcag tagatcgaac gcatcatgat
    17401 tatatcattc gtgcaatgaa aaaaggatat gatgttattt gcgaaaaacc tctgactatc
    17461 gatgaggaaa aagctcaaga aataataacg gtccaaaaac agacgggaag aagcctgcga
    17521 gtcactttta attatcgtta tgcaccgtat cacacgaaga taaaggaact gatagaaagt
    17581 gatgtgattg gtgatgtgtt ttctatccac ttcgaatggc tgttaaatac gcaacacggg
    17641 gcagattatt tcagaagatg gcatcgaaat aagcacaata gcggcgggct tcttgttcat
    17701 aaatctaccc atcattttga tctagtgaat ttttggttga acagccgtcc ccaaaaggta
    17761 tttgcattcg gtggattaaa cttttatggg atgcataatg cggagaaacg cggagtagaa
    17821 atattttaca gtcgatgcta tggaagcgaa ctagctaaag ctgatccatt tgctatagac
    17881 ctgtcagcca atgaggaatt gcgagaaatg tatttagaag cagaaaaaga cagtggatat
    17941 attcgtgacc gcagtgtatt ttccgatgat atctctattg aagatacact aggcgtaacg
    18001 gtcaaatatg aaactggtgc gattttgacg tattcgctaa acgcgtatat gccgtgggaa
    18061 ggattcaatg tttctttcaa tggcagcaaa ggacggatcg aaatgaaagt gatcgaaaag
    18121 tcttacatca atgcaggtgg agataaaaag gatgaaggag cagccgttct tcagtccatc
    18181 catgtctatc cgatgttcgg tgagccatat gaggtaatcg tcgaacaaga agcgggcgga
    18241 catggcggag gagatccgcg tttattagat gatctatttg gtgaagaaaa agaagaagat
    18301 ccgtggaatc gggcagcaac tcacgtagat ggtattttgt cgattttgac aggaatcgca
    18361 gcaaatcatt ctattgcttc aggaaaagca gtagtgattg acgagcttgt cagcttaaaa
    18421 gaataagaat agatttacgg aaattacttc ccgtagttta taaaatcttg ccttattgcc
    18481 gataggctgt cttttgaaca ctatttattc ggaaaaaggg gctatgacat gctttttgtc
    18541 atgccttctt tttatgtggg ctgctttttt agataggaga aaataaaaat aactatttaa
    18601 acccgaacaa aaaggaataa tgcattaaaa atcattagat tttacaaaaa aataagtaaa
    18661 ccacgttgtc agtttcagaa agtagtgtta gactgttttc aatatttgaa acaacatttt
    18721 ttattcaaat atggcaaact gccttcacgt gcaaaacagt tgcaagaaaa tgaatttaca
    18781 ctattattag ttttacatac ctacttatat atcgtcataa tatggatgac agtttctagc
    18841 cagtaccgta aatgctggac tataagtaaa agattggcta tttcaccctt cttttcttat
    18901 gataaagtgg agggtgtttt tctttaacag aaacatagta ggtttttgca caaaagcggt
    18961 tatttcggta ttaataaatg ataaaggagc aaataaagtg aaagaattag ttgaacgtat
    19021 tcaaaaagac ggacgtatat taggcgaggg cgtattaaaa gtcgacagct tcgtcactca
    19081 ccaagtagac cctgtattga tggaacaaat gggaaaacgg tttgcagaag tatttaaaga
    19141 acaaggaatc acgaaagttg tgaccattga agcttctggg atcgcaccag ctttatttgc
    19201 tgcaagagaa ttagatgttc caatgatctt cgctagaaaa gcaaaaagtt tgacgatgga
    19261 tgaagaatta ttgacagctt ctgtttattc ttttacgaaa caagtgacaa gtacgatttc
    19321 tatttctcgt aaatttttat cttcagaaga caaagtattg attatcgacg atttcttggc
    19381 aaacggacaa gcggcaaaag gattgatcga attatgccag caagctggag cgcaagtaga
    19441 aggaatcggg atcgtcatcg aaaagtcttt ccaagatgga cgtcagttac ttgaagaaat
    19501 gggattgaga gtcgtttctc ttgcgcgtat tgcttccttg acgaatggac aagttgagtt
    19561 tcttgaggag gacgcataat cgtggaaaaa gaaacacaaa atggaaaagc tgcggtttta
    19621 gggctgcagc atctgctagc gatgtatgca ggagcagtag cggtgcctct tttgatcggt
    19681 acaggactag gctttaatca agaacagatg acttatttga tttcaattga tatctttatg
    19741 tgtggattag cgacattatt gcaattgaca gttaaccgat ttttcggaat tggcttgcct
    19801 gtcgttttag gatgtgcgat ccaagcagta gctccactga tcttgatcgg aaccaatgaa
    19861 ggagtaggag ctatctacgg atctattatc gcttctggga tctttgttgt gttagtttct
    19921 ggtgtctttt ctaaaattaa aaaactattc cctcctatag taacaggaac ggttatcacc
    19981 gttattggtt tgactttgat tcctgtagca atcgagaaaa tgggtggagg taatgcaaca
    20041 gcagctgatt ttggtgacaa aacaaatctg ctacttgcat ttgtgacgat tctcctaatt
    20101 gtaggcgtgc aaatgctggc aaaagggttc attcgttcaa tcgcggtatt gattggttta
    20161 gtcggaggaa gcatcttagc tgctttcatg ggaatgattg atctgagcgc gattggagat
    20221 gcgccgttgt tccatgttcc acaacccttt tattttggta aaccaacttt cgacgtatgg
    20281 tcgattttac taatgatcat catttccatg gtcagcatgg tagaatcaac aggtgtatat
    20341 tttgcacttg gtgacattac tgggaaaaat gttggagaag aagaattgaa aaagggatat
    20401 cgtgcagaag gacttgccgt tatcttaggc ggtattttca atacattccc ttatactggc
    20461 ttttctcaaa atgtcggatt ggttcaactt tcgggaatca aaacaagaaa acccatctat
    20521 ttctctgcat tcttcttgat tgttttagga ttattcccta aaatcggtgc gttagcacaa
    20581 atcatccctg agccggtact tggtggagga atgttagtca tgttcgggat ggtggcagtc
    20641 caaggaatcc gtatgctgtt ggaagttgat ttcagcaatg ataaaaatct attgattgtt
    20701 gctgtttctg ttggatttgg gctgggtttc aatgttacgc cgacattatt cagtcaaatg
    20761 ccgcaaacat tgcaaatgtt cactggaaat ggcatcgtaa tgagtagcat tacggctatc
    20821 atattgaatt tgatctttaa tggattgaaa aaagatgaag aaatattgga agaagccttc
    20881 aagaagtaat agagcaaaag aaaggttgtg aaatcagcgt tttgacctga ttgttagaga
    20941 aacaaacgga aaaatagttc ctcgtatttt gccgtttgtt tgagctaata ccgagggtca
    21001 gctgattgaa caccgttgaa ggaagaggtc gtgagcctgc cgttcatctc cgagtcacaa
    21061 ggaacaattt caaaaaaaag cttctcatgt ttgttgaata ttgttccttg tgaccgagga
    21121 gttggcagga gaacaccgtt tatccataaa aaggaatgtg acctaacttt tgtcacattc
    21181 ctttttttta tctttaataa acacgaacaa taaaatgttt ttctttgtta acattcgaaa
    21241 tttctttgac atcaaaaaaa gtgattgtta aaatatgaat gtagaaaaac tgggaggaaa
    21301 aacaatgaca gcaaaaatct ctgtgattat ggggagtact tcagattggg aaacaatgaa
    21361 agaagcatgt caaatattgg atgaattcgg tgtgtcttat gaaaaaaagg tcgtttctgc
    21421 tcatcgaacc ccagatttga tgtttgaata tgcacaaaac gctcgaaaaa aaggaatcaa
    21481 aatcattatt gcaggagcag ggggagccgc gcatctgccg ggtatggtcg catcaaaaac
    21541 aactttgccg gttatcggtg taccggtcca atcacgaaca ttaaatggtt tggattcgct
    21601 tctttcgatt gtccaaatgc ctggaggagt acctgtagct actacagcaa tcggaaaagc
    21661 gggagcaatt aatgctggac tacttgcgat acagatgctt tccatgtatg atttagaatt
    21721 ggaggctaaa ttggctgaaa gacgttcaat gttggctaaa actgttatag aaagtagtga
    21781 tcaacttggt taaacctttg ttgcctggtt caacgatcgg gatcgtcggt ggcggtcaat
    21841 taggtcgtat gatggcgatt agtgcaaaag aaatgggctt taaagtaggt gtgctggatc
    21901 ctgtgagcga ttgtccagcc gcacaagttg cagattggca cattgaaagt gtctatgatg
    21961 acacctttgc gctgaaagag cttgccagaa gaacagatgt cattacctat gaattcgaaa
    22021 acgtcagtgt agaggcgtta aatgcgattt tacccatgtc atttattcct caagggacag
    22081 acttgcttgc gattacgcaa gaccgcctgt tagaaaaatc ttttttggaa acgaataaca
    22141 tcgtgattgc tccttatgca acgatcgtca gtccgacgga tatccaagat gcgattgacg
    22201 ggatcggcta tccttgtgtt ttgaaaacca ctcgaggcgg ctatgatggc aaggggcagt
    22261 atgttttgaa aagtcgggcg gatctagctc ctgccatgga ccttttaaga gaaggaacct
    22321 gtgttttaga agcatggatc ccgtttgaaa aagagatttc gatcatggtg gcaggaaatg
    22381 gtcaaggaga tttcacgact tttccggtcg tggaaaacat ccaccacaac aatattcttc
    22441 atgaaacgat tgctccagcc gcgattgatc aggatgtgat cgaggaggct gagcgtattg
    22501 cccgtgtgat tgcagaagca gtgagccttt caggtgtttt aggggtagaa atgtttttaa
    22561 caaaaacagg cgggctatat gtgaatgaat tagctcctcg tcctcacaat tctggacatt
    22621 attctattga agcttgttct atgagtcagt tcgatgccca tattcgaggt atttgtggtt
    22681 ggccattagg agaaaaagta cgtttgataa gcaatgcagt aatggtcaat gttttgggag
    22741 aacaactgct ggaaagctat cgcttgattg agaataagcc agactggcaa ttccatttct
    22801 atggaaaaaa acaagcaaaa aaaggtcgca agatgggaca tatcactatc ttgacagaag
    22861 acatccagca aacgctggaa gaaatcaaac aaacgaatat ttgggattag aggagaaaaa
    22921 acatgttaga acgttataca cgccctgaaa tggggaatat ctggacggaa gagaacaaat
    22981 accgtgcgtg gctcgaagtc gagattttag cagatgaagc ttgggcagaa cttggtgaaa
    23041 tcccgcaaga agatgtgaaa aaaattcgtg agcatgcatc atttgatatc gatcggatct
    23101 tggaaatcga aaaattaaca cgccatgatg tcgttgcgtt tacacgagcg gtttctgaaa
    23161 cattgggaga agaaagaaaa tgggtccatt atggtctaac aagtacggat gtcgtagata
    23221 ctgcttatgg ctatctcatc aagcaagcaa atgatatttt acgggaagac ttgaaacgtt
    23281 ttacggaaat cattggcgaa aaagcaaaag aacacaaata tacagtgatg atgggtcgga
    23341 cacacggtgt ccatgctgaa ccaactactt ttggattgaa acttgccaca tggtattcag
    23401 aaatgaaacg gaacatcgaa cgatttgaac atgcggcaaa aggagtagaa gcaggaaaaa
    23461 tctcaggagc agtgggaacg ttcgcaaata tcccgccatt tattgaagag tatgtatgta
    23521 aacaattggg gatccgtcca caagaaatct ctactcaagt tctccctcgg gatctacatg
    23581 ctgaatattt ctcagcgatg gcgcttattg ctacaagtat tgaacgtttt gcaacagaga
    23641 tacgcggatt gcaaaaatcc gaaacacgtg aagtagaaga attttttgcg aaaggtcaaa
    23701 aaggttcttc tgctatgccg cacaaaagga atccgatcgg ttcagaaaat atggctggtc
    23761 tagccagagt ggtgcgcgga cacatggtca ctgcctatga aaatgtcaca ttatggcatg
    23821 aaagagatat ttctcattct tcagcagaac gaatcatctt gcctgatacc acgattttat
    23881 tgaattacat gttaaatcgt tttggcaata tcgttaaaaa tctaacggtc tttcctgaaa
    23941 acatgaagcg gaatatgtct gcaacatttg gtttgattta tagccagcgc gttatgctga
    24001 aattgatcga taagggaatg acaagagaag aagcttatga tcttgttcag ccaaaaactg
    24061 cgtacgcttg ggacaaccaa gtgcagttcc gcccgctgtt agaagaagat ccaaccatca
    24121 catcggtatt atctaaagaa gaaatagacg atgcctttga ttatcatcat catttgaaaa
    24181 acgttgacgt gatattcaaa cgagtaggtt tggaataaag aagagtgagt tgcaaaattc
    24241 aattaaaata gaatagcaaa aataatcgag tagaggggaa agccaactga ccttccgccc
    24301 ctctcacacc accgtacgta cggacccgta tacggcggtt caataagttg agtgtacgaa
    24361 ctggtacttc aaggagatgt cctcatatcc ttggcgggcc agttctttgt ctgttaatga
    24421 tcgatgaaga atatgacttt tggagactga ccaaatacct tttcttgtat ttgaccattc
    24481 atacgctttc gctttatcga tccctaaacg aatcagattt tttcttttgg ttcttggatt
    24541 cttccattgt ttccaaatat attgtctgat tcttcgcttc aaccaaccgt ttaactccct
    24601 catgaattct ttcatctcac caattccata gtagttgatc caaccagtca ttagttgctt
    24661 gatttctttt aaaataagtt ggatacttct tccacggttt cttttagtga gttgtttgag
    24721 cttgcttttc acacgctgtt ttgcttttgc gtgagggcga attttaatac ctttctttgt
    24781 tggcagaatg cagaatccaa gaaactttcg tttcaatgga cttcctaccg cactcttttc
    24841 tcgatttacc gtcaacttta gttgttcttc gagaaattga atggatttct tcatcacacg
    24901 ctgtcctgct cgtttgcttc taacatagat attgcagtca tcggcgtatc gaacaaattt
    24961 atgtcctaga ttttctagca cttgatcaaa ttcgttcagg tagatgttac ttaacagggg
    25021 agagagattg cctccttggg gcgttccttc ttcagttgtt gtgatgagtc cattttccat
    25081 tacaccactc attaagtatt gacggatcag ttttaggact tgtttgtcct ttactttccg
    25141 ctcaatgaaa tacatcagct tatcgtgatt tacggtgtca aagtaggctt tcatatcaat
    25201 gtccaccaca tatcggtaac cttgttcata ataagatttt gctttcttca ctgcgtcatg
    25261 tgcgctgcga tttgggcgaa acccataact attatctgag aattctggtt caaatagcgg
    25321 ttgtaacact tgattgattg cctgttgaag catacgatca ataaccgtgg gaattcctag
    25381 ttttcttaca ccgccgtttg gtttcggtat ttctactcgc aaaacaggct gaggtttata
    25441 gttcccttgg cgtaaattgg atagtaattc ctcgcggtgc tctttcaagt aaggaagcag
    25501 ttgatcgacg gtcatcccat ctgcaccagc cgccccttta tttctgacta cttgaagata
    25561 cgcttgattg agattattcc gatctagaat tctcccaaac agattttcta caccatcttg
    25621 tttcctctgt tcaccgcaag aagtgctgcg cacttcatca tacccttcgt gttccacact
    25681 agctctttga tgatagccaa gttttcttgt tttctgcggt cgtcgcatct tctcacacct
    25741 cctaaattat tcaagattct tattgttcag tccttcgtaa cggtcagtgt cgttactact
    25801 atgacctcgg ctgacttctc atgattcacc atcatgtcgc catgatcgtt gtgctggttt
    25861 gttttcattc aacgcccaca acaccctcat gagatctccc ccggtaagag tgaaaacttt
    25921 cctcccatgt aactgctaga tttactgtat aggtttcggg cagtattgga ctttgtcttg
    25981 tgatgaagac ttatccgacc taattcagcc ttgtatctag tttctgttcg tcagttcagg
    26041 agtttgcgtc cgacttcctt cagccacaac ctcacgattg ccgccttgtc tttcgctaac
    26101 agttcctact gccaagcctg tagtggactt tcaccaccaa gttttcaccc atgcagggcg
    26161 cacaccaaaa aagaagcaga tccgttagcg gttctgcttc ttttagttta ttatattttc
    26221 ttatcaataa taggaacctg attttaaaag cggctacctc tttaccgtgc ctctttacat
    26281 acaaaaaata gaggaattaa gcgtaaatgg cttggctatt ataactaaaa tgctggttat
    26341 ggagatgttg cagcaagttt tcgagaaaag cgtattccat ctcttgtcca ttgaataaga
    26401 tctggatacg ataatgattt ttgaaacgct tctgttcatg aatctgactg attgaaagtt
    26461 cgcctttgtg ttctgtctga taaagaaaag tccttttacg gcattcagca cagcgcttgg
    26521 ttgctcggcg gatttttcgg aatgtataaa aactagtatc tttattgcat aaataaacgt
    26581 ctttgatcga cagcaaatca ttatatagac aggaacgttc ttcagctgtt aattctgata
    26641 aaaaaagctg accttgtttt attgcatctt ccatcggcaa gtgcctcctc gaacccatta
    26701 tccaaatttt tagttaattc taatatacca tcattaagta taaatgtaaa cgcttgttga
    26761 tggtataaga ttttcgtttc tgataaaaca cgaacattaa aagaatctaa tgccttaaat
    26821 gtacatattt ttgttgattt ataaaaagat gattgctaaa atttaaagtg aaaaaacgaa
    26881 caaaaaacga tgtatttgct tttaatgtaa ataaaaagga gagacgtaca tggagaagaa
    26941 agaacttttg tatgaaggaa aagccaaaaa aatatatctt acttctgatg agaacttgat
    27001 ttggatagaa tatttagatc aagcaactgc gttgaatggc gcgaggaaag accagataag
    27061 tggaaaagga gaattgaata atcaaatcac aagtgcaatt ttccgttatc tgactcaaag
    27121 aggaataaaa aatcatttta ttgaacaatt gtctaaaacc gaacaattag caaaaaaagt
    27181 acaaattatc cctctggaag tggttatccg aaatattgca gcaggaagtt tctcaaaacg
    27241 tctaggtgtt cccgaaggta aagaattcat caaaccaatc attgaattct actataagga
    27301 tgaccagttg gatgatccat ttatcaatga agagcatatc tatttcttac aacttgcaaa
    27361 gccggaagaa atcagtgagc tgaaagccca agcgttggct attaatgaaa ttttgaccga
    27421 attatttgct aaggtcggtt tggttttagt agatttcaag ctagaatttg gccggtcgaa
    27481 tggacaaatt ttgcttgcgg atgaagtaac accggatact tgccgattat gggatgaacg
    27541 tacgaatgaa catatggaca aagacgttta ccgcagagat ctaggtgatt tgatcccagt
    27601 ctatcaagaa gtatataacc gtctatcgga actaactgaa gaaaaggagc gagtatgatg
    27661 tatttcgtaa aagtatatgt aacctataaa gattcagtgt tagatcctca aggggaggca
    27721 gtaaaaaaag cagtccatcg tatgggatat gaaacaatcg aagatatccg aataggaaaa
    27781 tactttgaga tacaacttgc tgatgcagaa gaaccaatcg atacagtgat tgaaacgatt
    27841 tgtgacaagc tgcttgcaaa tgtaaatatg gaaacatacc gatatgaaat caaaaaaatg
    27901 gaggaagtat aacatgaaat ttgcggtcat cgtttttcca ggttcaaatt gtgacgcaga
    27961 tatgttatgg gcagttcgcg agatcatggg cgctgatgcc gaatttgtac ggcatgatga
    28021 gtcctcttta gaaggatttg atggggtttt actgccggga ggattctcct atggtgacta
    28081 tttgagatgc ggtgcgattg ctcggttttc tacaatcatg gaagaagtga ttcgttttgc
    28141 tgaagaaggg aaaccagtat tcggtacatg caatggattc cagatattga cagaagcagg
    28201 acttttgcca ggtgtactga gacgaaatga gtctttgcat tttatttgca aaactgtacc
    28261 attgaaagtc aaccccaaga cggcctttac ttcagagtat gaagccgacg aaataatcta
    28321 tcttccagtt gctcatgggg aaggaaatta tttctgtgac gaagaaacac ttcaagaact
    28381 aaaaaaaaat aatcagattg cctttactta taatgacaac atcaacggca gcgtggaaaa
    28441 cattgcaggg attacgaaca aagcagggaa tgtgttagga atgatgcctc atccagaacg
    28501 tgcagtagaa gacttgctag gatcagaaga tgggaaacgg ttctttgctt ccattttaaa
    28561 aaacttcgga aaggtgaccg tatagatgaa aacattgaaa gaaccgacag ctgaagagat
    28621 caagaaaaaa agaatctatg ccgaatgggg attgactgat gaagaatatc gaatgatcga
    28681 agaagatatc ttaggaagaa tgcctaatta tacggaaact ggactgtttt ctgttatgtg
    28741 gagcgaacat tgttcctata aaaattctaa accggttcta cgcaaatttc ctactagtgg
    28801 acctcatgtg ttgcaaggcc ctggagaagg cgcaggcatc gtcgacatcg gtgatggact
    28861 agcagttgtc ttcaaagcag aaagtcacaa tcatccttca gccgtggagc cttatgaagg
    28921 agctgcgaca ggagttggcg gaatcatcag agatattttc agcatggggg ctcgtccaat
    28981 tgcgttgcta gattcattga ggttcggcga attagataat ccaagaacga aatatttact
    29041 agaagaagta gttgcaggta tcggcggata cggcaattgt atcggcatac cgactgtagg
    29101 cggcgaaatt gcatttgatc cttgttatga aggaaaccca ttagtcaatg caatgtgcgt
    29161 aggtttgatt gaacacaaac atatccagaa agggcaagcc gctggcgtcg gtaattcgat
    29221 catgtatgta ggtgcaaaaa caggtcgcga cggtatccac ggagcaactt ttgcctcaga
    29281 agaatttaat caagaagaag aacagcaacg ttctgctgta caagtaggcg atccttttat
    29341 ggaaaagctg ctgcttgaag cgtgtttgga attaatcttg catcattcgg attctctaat
    29401 aggtatacag gatatgggag cagcaggact tgtttcatct agtgcggaaa tggcttcaaa
    29461 agctggctca ggacttatat tgacattaga tgaagtccca caaagagaaa ctgggatgac
    29521 accttatgaa atgatgttat cggaatcaca agaacggatg ttgatttgtg ttaaatcagg
    29581 agaggaagaa aaaatccaag aactatttca gaagtatgat ctagatgcag tcactatcgg
    29641 taaagtaaca gacgacgggc aatatcggct atatcatcaa ggagaagaag tagcaaatct
    29701 gccagtcgat gcattagctg aagatgcacc agtttatcat aaagaaatga aagaaccagc
    29761 tcgaatcgta gaatttcagc agttagctcc ttatcagcca gttatcgaag aacctggaca
    29821 agtattgctt gatctgctgc agcaaccgac gattgcttca aaacgttcaa tctacgaaac
    29881 ttatgattca caagtacaaa ccaatacagt tgtccgtcca ggaagcgatg ctgctgtgat
    29941 gagggttaga gggacgaata aagcgttagc tatgaccaca gactgcaacg cgcgctatct
    30001 gtatttggat ccaaaaatcg gaggacaaat agcagtggca gaagctgcta gaaatattat
    30061 tgctagcggt ggtaagccct tggcgatcac cgactgcctg aactatggtt ctcctgataa
    30121 accagaagtt ttttgggaat tatcgacttc agctgacgga attgctgctg cgtgtgaaac
    30181 gttaggaact cctgttattt caggaaatgt ctctttatat aatgaaacgg atggtcaagc
    30241 aatctatcca acaccaatga ttggtatggt cggattgatt gaggatcata aacatatcac
    30301 tactcaggaa ttcaaaaaat caggggatct aatctatata ttaggtaaga cgtttgcaga
    30361 ttttgatggc agtgaattac aaaagatgca gcttggaaga atcgaaggtg tgatccgaaa
    30421 ctttgatcta tccattgaaa agagaaacca agagttagta ttgacagcca tccaaaacgg
    30481 attgattgaa agtgctcatg actgttcaga aggtggcttg gcaattgcac tggcagaatc
    30541 agctttcaaa catcagctag ggatatctgt acagtttgaa ttgtcctctg ctcaattatt
    30601 tgcagaaact caatcaagat ttgtgttgac agtcgcaccg gaaaataaga cacgattcga
    30661 agaaatgatg ggagatgctg ctgttttagc aggtaaggtg acggatgaag cgataatcga
    30721 aatttcagca actgacggtc agatcaaaat agaaactgca gtagcaagaa agtgctggga
    30781 ggatgcaatc gtatgtctta tgaagtgaag agtttaaatg aagaatgcgg gatcttcggt
    30841 gtttggggtc atccagacgc cgctagtgtg gcatacttcg ggctccatag tcttcagcat
    30901 cgaggacaag aaggtgcagg tatcgtgtcc aatgatcgag gaaagcttaa ggggcatcga
    30961 gatttggggc tgctttctga ggtattcaaa gatcaaagaa aattgcagca gttaacagga
    31021 gaagctgcaa tcggacatgt acgttatgca acagcaggca atggaagtgt ggacaatatt
    31081 cagccttttc tattcaaatt tcatgatcag tcgatcggct tagcgcataa tggtaacttg
    31141 atcaatgctc gttcccttag aaaagagtta gaggaaaatg gggcgatctt ccattctaac
    31201 tccgatacgg agatattgat gcatttgatc cgacgaagtg aagaaacaga ttttttaaat
    31261 aaattaaaaa gtgctttgaa tgaagtcaaa ggtggctttg cctatttatt aatgacagaa
    31321 acggcaatga ttgccgcttt ggacccaaat ggttttcgtc cattagcaat cggacaaatg
    31381 aaaaacggag catacgtgat tgcctcggaa acttgtgcat tagaagttat tggggcacgt
    31441 tttataagag atgtccagcc tggtgagata gtgatcatca atgacgaagg aatccagatt
    31501 gattgcttta cgaaggacac gcagctttct atttgttcga tggaatatat ctattttgcc
    31561 agaccagatt caaacatcgc agggatcaat gtgcatactg cacggaaaaa tatgggacgg
    31621 aatttagcga aagaatcgcc agtaaaagca gatatggtcg ttggcgtacc taattcttct
    31681 ttgtcagccg caagcggtta tgcggaagct agtggaatcc cttatgaaat cggattagta
    31741 aaaaatcaat acattgcccg aacatttatc cagccaacgc ctgagctaag agagcaaggt
    31801 gttcgaatga aattatctgc tgtacgagga gtagtggaag gtaaaaaggt gattatggtc
    31861 gatgattcaa ttgttcgggg tacgacaagc agacggatcg tccatctttt gaaagaagca
    31921 ggggcaaaag aagtccatgt gaggattgct tctcctcctt tgaaatatcc atgtttttac
    31981 gggattgata ttcaaacgcg taaagaactc attgcggcaa atcacacgat tgatgaaatc
    32041 aaagaatgta tcggtgcaga ttctttaggt tttttaagtg aagagggtct gatcgaatcg
    32101 atcggtctgg aaaaagatgc tccgtattca ggattgtgta tggcttattt caacggagat
    32161 tatccgacgc cgttatatga ctatgaagaa aaatatcagg aatcactaaa agaaaaagta
    32221 tcgttctttt aaaagcagac caagaaggga gtatatgaat tcaatggcaa atgcatacgc
    32281 aaaagctggc gtagatgtcg aagctggata tgaagtagta gaacggatca agaagcatgt
    32341 caaaaaaacg gaacgtttag gtatgatggg cgctatagga ggattcggcg gttgttttga
    32401 tttatcggtc tttcaattaa aagagccagt ccttgtctcg gggaccgatg gcgtggggac
    32461 gaaattagca gtggcaatcg aagcagacaa acacgataca atcgggatcg actgcgtagc
    32521 gatgtgtgtc aatgatatct tagcacaagg cgcagagccg ttatatttct tagactactt
    32581 agcaacgggg aaaaatgatc cgttacgttt ggaaaatgta gtaaaaggtg tagcagatgg
    32641 atgtgttcaa ggaaatatgg cgctgattgg cggagaaaca gctgaaatgc ctggtatgta
    32701 ctcaggtaat gattatgatc tagccggatt tgctgtaggg atagctgaaa aatctcaatt
    32761 attgacagga gaaacgatca acccaggaga tgtgttgctt ggaatagcat ctagcgggat
    32821 tcattcaaat gggtactctc ttgttcgcaa aattttcttt gagcagcagc agttttcttt
    32881 atcatcaaaa ctgccagaat tgaaaaaaac acttggcgaa gaattgcttg agccaacgaa
    32941 aatctatgtt tcttccttgc ttccgctgat caaagaaaag aaaataaaag gagctgcaca
    33001 tatcactggt ggagggtttg tagaaaatat cccgcgaatg ttaccagaat ctatggctgc
    33061 acaaatcaaa cttggctcat ggccgattct tccaatattc ggctgtttac aaaaatatgg
    33121 tgaaattcct gagatggaga tgtatgaaat cttcaatatg ggcatcggta tggtcctggc
    33181 agtccaagaa tcgaaagtaa aagaaatagt acacgaaatt gagcaagctg gcgaaaaagt
    33241 ttatgaaatc gggaaagtga tcgccaaaga aaaacatcgt gtggtgttta taggagaaga
    33301 acgatgagaa tcgctgtttt tgcttctgga aacggaagca actttcaagc gctagccgat
    33361 tatctatcga aaaaaggatt ggaatcttcg attgactggt tgttttgtga tcagcctgaa
    33421 gcatatgttt tgaaacgtgc aactgcgttg agtgtaccgg cagattgttt ttcacctaaa
    33481 gaatttgatt caaaaaaaga gtatgaagaa gcaattttgc ataaattgaa agaaaaaaag
    33541 atcgatttga tcgtattagc tggatatatg cgaatcattg gaccggtatt gctgaaaaat
    33601 tatgataaaa gaatcatcaa tatccatccg tctcttttac ctgccttccc tggtttgcat
    33661 ggcatacgtg atgcctttga agctggagta aaagaaacgg gtgtcacaat tcattatatc
    33721 gaccaaggtg tagatactgg accaatcatc cggcaggaaa aagtgagaat tgaacaggag
    33781 gacacgttcg attctttaga agaaaaaatc catagagtag agcatcgaat ctatccagaa
    33841 gtgattagtg aaattattga aaatggaggc tatctgaaat gacaagagca ttgatcagtg
    33901 tatcagataa aactgggatt gtagcattcg cccaaggttt gattgaacaa ggagtagaaa
    33961 tcatttcaac aggaggaaca aagcatgcgt tggataaagc tgggatcaaa acgctttcga
    34021 tcgaagaagt gacagggttt cctgaaatga tggatggccg tgtcaaaaca cttcatccta
    34081 aaatccatgg tggtctttta ggaagacgcg atctccctag ccatatggag gcaatggaaa
    34141 cggaaaatat ccaaccaatc gactttgttt gtgtcaattt atatcctttc aaagaaacga
    34201 ttatgaaacc agatgtcgaa atagcagaag ctattgaaaa cattgatatc ggtggtccta
    34261 gtatgctccg tagtgcagca aaaaaccatg aatttgtcac ctctgttgtt gatccatctg
    34321 actatgaaga agtactttca gaattacgtc agtatgggca tacttcactt tctttcagac
    34381 aaaaactagc ggcaaaagtc tttcgtcata ctgcggcata tgatgcactg atcgctcaat
    34441 acttaacgga ttgggtggaa gaaaaagaac cggaaaaatt gacacttacg tatgaacgaa
    34501 aacaaacgct tcgttacggt gaaaatagcc atcaagccgc tgccttttat cagtccgctc
    34561 ttctggaaaa atattcgatc gcagcagcaa aacaactcca tgggaaagaa ctttcttata
    34621 ataatatccg agatgcagat gctgcgctac ggatcatgaa ggaatatgac gagccaacgg
    34681 tagtcgcctt gaaacacatg aatccttgtg gtattgggac agcatctacg attttagaag
    34741 cgtgggaagc agcgtatgaa gcagatcctg tttcaatctt tggtgggatc atcgttttga
    34801 atcgagaagt agatctgcca acagcagaac agatgcataa gctgtttcta gaaatcatca
    34861 ttgccccttc ttatacacaa gaagctttgg aattactgca aaaaaagaaa aacatccgat
    34921 tactgacagt agactttgcg caggaagaaa atcaaaatcg agaagaaacg gtctcagtct
    34981 taggtggact tcttgtacaa gatcaagatc tggcaataga aaatgaagaa gagtggaaag
    35041 tcgtgacaaa acgtaagccg actccagcag aagcaaaagc attagcgttt gcttggagag
    35101 ctgtcaaaca tgtgaaatct aatgcgatcg tactggcaaa cgaacgtcag acagtaggaa
    35161 tcggagccgg gcagatgaat cgagtcggtt cagtaaaaat tgcgattgaa caagcgcaag
    35221 agaaaatgga aggtgcagtt ttagctagcg atgcttattt tccaatggat gattcggttg
    35281 aatatgcagc caaacatggt ataaaagcaa tcattcagcc aggaggaagc atcaaagacc
    35341 aagattctat tgatatggcg aataaatacg atctagcaat ggtctttact gatgttcggc
    35401 attttagaca ttagagagga gtcggataaa tgaacatttt ggtgatcggt gcaggtggtc
    35461 gtgaacatgc aataagtaaa aaacttttag ccagtccgaa ggtggatacg gtgtattgtg
    35521 cgccaggaaa tccggggatg acaaaagatg gtatcaattg tgtcgctatc agtgagcgag
    35581 atcattcagc gttaatccat tttgttaaga aagaggctat tgattggagt atcgttggtc
    35641 ctgaagttcc tttgttaaat gggatcgtcg atgattttat ggcggaagga ttgaaaatct
    35701 tcggtccgac aaaagcagca gctctgatcg aaggttcgaa aagttttgct aaacaattaa
    35761 tggatactta tcaaatcccg acagctaaat ccagaagttt tgaatgttac gaaaaagcag
    35821 cagcgtatat caaagaaaat ggtgcgccaa tcgtagtgaa agcggacggc ttagcagctg
    35881 ggaaaggtgt agtcgtggct accacagtga aggaagcgct ggatgcggca gaacaaatgt
    35941 tgaaccagca tcgatttggg gatagtagca aaaaaatcgt cgtagaagag tttttggcag
    36001 gagaagaatt ctcccttttg gcgtttgtcc gtaataccaa ggtgtatccg atggtcattt
    36061 cgcaagatca taagcgggca tttgataacg ataaagggcc aaatacaggc ggaatgggtg
    36121 cttattcacc agtaccgcaa atttcaaaaa agatgattga aaaagctgtg gaagaagttt
    36181 taaaaccagc ggctttggga atgaaagaac taggacgctc tttcacgggt gttttatatg
    36241 cgggtttgat tgctacgaag gaaggaccaa aagtgatcga attcaatgcg cgtttcggtg
    36301 atcctgaaac gcaagtcgtt ctttctcggt tgaagagtga ctttgcgcaa gtaatcgatg
    36361 atttattaga gaatcgtaca gtagagttaa agtggcagca agaaggatac aatgtaggcg
    36421 ttgtggttgc agctgccggt taccccgaag aatatgagac aggaatggtt ctaccagatt
    36481 ttctggaaga agagctttct gtttactatg ctggagtttc ctcaaataac ggcaaactag
    36541 ttggagcagg aggacgtctt tatttagtag aagcatacgg tgagacgatc aaagaagcac
    36601 agaaaaaaat ttacaccgcg ttaatggata aaacgacaga tggaacattt tatcgtacag
    36661 atattggaga aaaagctgcc aatagcgaac tgatcgtgaa gtaaatcagc tgcttccatt
    36721 tataaaaaat acaacaaaca taatcggaag cgccgatttt agtgaagcct tttcataaag
    36781 agtgtggtac acttttgttg tgtatataaa taaggaggag ttcagatgaa aaaaattcaa
    36841 ttaggtactt ctgatcagaa agcagctgca gtgatcttag gctgtatgcg tatcaacaat
    36901 gcggaagatc cagtaaaagt gattgagaca gcttatgaaa acggcattga tttttttgac
    36961 catgcagata tttatggaaa cggtgaatgt gaagaaatct ttgcagatgc tctagcaaaa
    37021 acatcaatca aacgagaaga tctttttatt caaacaaaat gtggaatcgt tccaggtgtg
    37081 atgtttgatt tttctaaaaa acatatcatt gaatctgtag aaaaaagttt gacccgtctg
    37141 aaaatggatt atgtggatgc tttacttctt catcgtccag atacattggt agaaccagag
    37201 gaagtagctg aagcgtttga tgaattggaa cggtcaggaa aagttcgtta ttttggcgtc
    37261 agcaatcaaa aaccaatgca aatcgaattg ctgaaaaaat atgttcgtca accattagta
    37321 gctaatcagc tgcaatttgg cttgaaacat actggaatga tcgatcaagg gattcatgtc
    37381 aatatgacag atgaagcaag tatcgatcat gacggtagtg tacttgatta ttcccgattg
    37441 catgatatga cgatccaagc atggtcacca taccagtatg gattttttga aggtgtattt
    37501 atcgggaacg aaaaattccc tgaattaaac caaacattag aagaactagc agctaaatat
    37561 caaacgacac caactggctt ggcttctgct tggattttac gccatccagc caatatgcaa
    37621 gtgatcgccg gtacgatgaa cgtagggcga atcaaggaaa tcgctcaagc ttcagaaatt
    37681 aatatgtctc gggaagattg gtacgaattg taccgtgctg ctggaaacat tttaccttaa
    37741 agattgtcat aagcaggtca aaagggctat aaattaaaaa gacagaataa cttgaaagct
    37801 gttttcagct tcgagatatt ctgtcttttt ttattgcaaa tggaaagagt atcattgtac
    37861 ggatttcgtt tattagttat ttttgttttt aaggaaaagc tgtgtccgat attcttttgg
    37921 agaaatccct tgttttttct taaataaata actgaaatag ttagggtcat tataaccaat
    37981 ttcaaaagca atatctgaaa tacgatagtc tgattgctgc aataattttt ttgctaattc
    38041 gattctttgt tctgtcagat aatcgatgaa tgtttggtta aacgattgag aaaaaatcgt
    38101 actgaaatga gagggactta atgcaacttg ttgagcgacc caagttaagg acatatctgg
    38161 atcggtaaaa ttttctttga taaaatccaa tgcatggttc aaaattggct gatatttgtt
    38221 ccttgaaggc tgtgagggca gagcagttaa gaaagaaatg aacatataaa ctgtcgaacg
    38281 gtaaagcgag tcgtcggcgc tgattgctaa gcgttgactg gtggatgtgc aatgaaccat
    38341 ttcttgcggg attttctttt ctttcaggca gacatgctgg agtagcttag tcaagacaaa
    38401 taaacgatat aatcgtgttc gagttggtgt gccttgtggt ttcgtcaagt gttcgatgta
    38461 cttagatact tcgtttttcg ataatgaaga caaatcaagt gagaggtcaa agtaaaagac
    38521 agaatcaact ggaagtttcg cttcttgaat caaatcctca tagctgataa tttgttcttt
    38581 aagggaactg gcggtttcaa gtatcatctg cgtgatctca aaagatgcag gtaattcgct
    38641 gattctttct gcgacaggac caatggcgac agaaaaatta tttttttgtc ccttttctaa
    38701 ttcatggacc aacgtttggg ctacctgata actggtctcg atcacatttt cttcaagaga
    38761 atcaactatt aaaaatttga tgaatcgaga ggaaacagca gagaagatca cttgttgatt
    38821 ctccctaaat aaaaacttca aataatcact gagatgagcg taatcttcaa agtctgtact
    38881 gacttggttt gctgctaata atacggtcat ttttttccct gctaaagagc gattgaaaga
    38941 ttcagcaagt ttcaatgttt cactgatcgt aagtgagcct ttgaacaaac cgttcaagaa
    39001 atgatttttt ttcaattcga aaacaagatc agaagaagtg tgcgtttctt tttgctgcaa
    39061 atctaaagca gttactgctt tttctattgc ttgtttcaat tcgctacttt taatcggttt
    39121 aagcagataa tcatctgcct gtacctggat tgctcctttc atataatcga aatcgtcgaa
    39181 tccactaata aatatgagac gagtccaagg aagtagtttc cttgcttctt ttgaaaaagt
    39241 caacccgtcc atgaaaggca tttggatatc agtcagaatg atgtcgggct gtaagtcgat
    39301 aattgaagac agtgccatct caccatctcc agcttcgccg acataagtga ttggataata
    39361 agaaccaagg acagttattt gttcccgcaa gttattgcga atgaggtatt cgtcttcgat
    39421 gataaaaact ttatacatgt ttgtttcctc caattgtttt gggagataga gggatcatca
    39481 gtgtgacagt tgttccttct cggtatttgc tgtcaatcgt gataggtttt tgatcatttc
    39541 cgtaataaag aaggagacgc ttgtttacgt tgtaaagtcc gtagccgata ctgaaatctg
    39601 aatcgatccc tttggctaac tctttacgta tttctgccag tttttctgca gggatgccaa
    39661 tcccgttgtc tataactttg aattggatca tctcatcaat tttgcatgtg gtaatacgaa
    39721 taaatccttt gtgacggacg tacttcgttc catggtatac agcattttca atcaatggct
    39781 gcaagatcat ttttaaaata gaaacaggaa aaagtgtttc tggtatatcg atcttatagt
    39841 caagcatatg gccgtatctt atttttaaga tgactagata atcattgata tggctaattt
    39901 ctttttcaag aggaatccag tcttgtcctt tgcttaaaga cgtacgaaaa aagccggaaa
    39961 gtgcatgggt catagtcaga gcttcttcaa agcagtcttg ttcgatcaaa gaaataatgg
    40021 catccaaact gttataaata aaatggggag taatctgagc ttgcaataca cgaacttcac
    40081 tttgtgctaa atggtattgt ttcaaagcgt tctcccgtaa agactggttt agatcttccg
    40141 ccattttatt catgctagcg gtaagtgttt gtaattccag tgtttccggc agggttaaac
    40201 gaaagccaag gttccctgaa gaaagttgtt ctgacatctc gatcagctga ttgatcggtt
    40261 cttggacctt tctctctaaa aagcgacgat tctttttcgc atagaaaaaa atggtactaa
    40321 gaactccaag ttccactatt gttaatagaa tgagcgagcg gacaagtgtc gtattttttt
    40381 tgcttgctaa gtcgatctcc acacgaacaa aatcttgtaa gatatctgac agcagttgag
    40441 tgacagaatc tacctgattg atgatctctt cattggtatc cataaaatct tttgccaaga
    40501 tattattgat cagctcgttt tgataatctt ccagtgtatc gatcgtacgt agcgatacat
    40561 ctaacgtact aatttcttta agtgtatttg tattattttt gatctctcga atatcattcc
    40621 taagttcttc taggatattt tcctcattga actcatctac ggttacttgg ccagaaatca
    40681 agtcccacat actttccaaa actttttgat caaccttcaa agcaattgca tctgcttttt
    40741 ggatatttgc gatcgtctgt tgataaatca aaagctgttg cgaatataac agtatgctca
    40801 gtagcaaagg gataacagca aatagaagca tggctttgtt tgcttgggca aaaatctgtt
    40861 ttatgcttaa attttttgtc atgatacttc tccagtcaat aatttctggt tgggatgtta
    40921 gctatattct gctgggaaaa gacagtctcg gaaataaaaa tatctttagg taatgttttt
    40981 cctgtttgaa tatttccaaa ataacgagta acggtattgg ctacatacca gccgacatca
    41041 ggtttacact cgactacaca attgacgatt cctgagcgta gcttctcgat catatcttct
    41101 tgtccatcaa tagttacaat gatcaaatct tctccaggtt tgattgatgt ttcttttatc
    41161 gcagctaaag caccgtgagt catttcatca ctatggctgt ataatacatc gatttcggat
    41221 aaatcatttg tttctaaata tcgtttcatc tggtcttttc ctttcatccg aataaaatca
    41281 ccgacaattc ggtgaacaat agtcatcgga ggtttatggt cgatggttcc atcttttttt
    41341 agggttggtt tacgattgat tgattccaaa aatccttcgg agcgtagctt ggtcggtgtg
    41401 gagttctctg aaccagcaag ttctaggatt ctgatttcct gtttctttga atttgtgaag
    41461 tgattgctga caaataaacc cgcccgattt ccttctgctt tgaaactggg gccaatgtgg
    41521 gtgacgaaaa gctcgggatc attcgtttga atatgtctgt cgacaagtat gacagggatc
    41581 cctgctcgct ttgcttcttt taatacagag tcccacccgg attcttgcaa aggagtaaaa
    41641 atgatcatat ccactttata ggcaatgaac gtccgtatat cttggatttg ccgttcctga
    41701 ttcatgtagc catttcggta gagaacttgg taatcttctt tttcaagcgc agtgataatt
    41761 gattcagtat gctttttccg ccagctactc tccgttcctg attgcgaaaa accaacgact
    41821 agtgggtcag gtgcttcctt tgtattaggt gtacacccca tcatttggta agcgattaca
    41881 acaagggcta aaaaaaataa aacacgtttc actttaaatc actccatctg gatttgttag
    41941 tactatctta tcagataaaa gggaaaatca aagtcaaaag gaatcaatcg aaaaaaatcc
    42001 aagaaactta aaaaaatcca agacaaaaaa agtacaccta aaaaatttaa agtaaatccc
    42061 ataaaaaaat caatgttaac gctttcttta ttagctatac tcggtgtatc aattgaaatg
    42121 ggggataaaa aatgaaaaac aaatttagaa agattgttgg gactatcgct attttgaccg
    42181 caagcattct attaagtgcg tgtggcaatt caggatctgc agatgatagt acggggtatg
    42241 taggaatcgc tatgccgacc aaatcagcag aaagatggat cgctgatggg aacaacatgg
    42301 tctcggaatt agaaaaactg ggttataaaa cagatcttca atatggagaa gataaagtag
    42361 aaaatcaagt agcacaaata gaaaatatga ttacaaaagg ggtagataca cttgtgattg
    42421 cttctatcga tggttcggct ttaactgatg tgttagctaa agcaaaagaa gcagatatca
    42481 aggtgatcgc ctatgatcgt ttactgatga attcagaaaa tgtcgattat tacgcgactt
    42541 ttgataattt tggagtaggt gtatcgcaag cagcttatat tgaagagcac ttaggattga
    42601 aagaaggaaa aggaccattc acgattgaat tatttggtgg ctcgcctgac gacaacaacg
    42661 cactaatcaa ttacaacgga gtgatgtctg ttttacaacc atatatggac aacggtcagt
    42721 tggtcgtgcc atctggacag acgagtttca gtcaaatcgc tacgcttcgc tgggatggtt
    42781 ctacggcgca agcaaggatg gataatctgt taagcgcaaa ttatactgac caaacattgg
    42841 atgctgtttt gtcgccatat gatccaataa gtttaggaat catttcgtca ttaaaaggcg
    42901 tggggtatgg gagtgaaagt aaacctttac ctgtgattac tggacaagat gcgacagttg
    42961 ctggcgttaa atcgatcatt gccggggaac aaacacaaac gatctttaaa gacacacgta
    43021 tcttagcaaa aaatacgatt gaaatgatca aagcaatcag tgatggagaa gaggttccgg
    43081 tcaatgatac tgaaacttat gataatgggg tgaaaactgt ccctacgtat ttagcaaata
    43141 cagtatctgt cgataaagat aattatcaag cagagctgat cgacaccgat tattataaag
    43201 aatccgatct gaaaaattaa gaggaaccaa acaaggaact aaagagatct aagtcagaga
    43261 gaggataaga attatggcgg attgtatttt aaaaatggca gatatcacca aaaaattttc
    43321 tggaatccga gcgttagatt gcgtgaatct gatgattgaa cgtggggaaa tccatgcatt
    43381 gtgcggagaa aacggagcgg gaaaatcaac attgatgaat gtcttgagcg gcttgtatcc
    43441 atatggctcc tatgacgggg aaatctttta tgatggaaag ctgtgtcaat ttaaagattt
    43501 gaaagatagt gaagaaaaag gcatcgtcat cattcatcaa gaattagcac taagtcctta
    43561 tctttcaata aaagagaata tttttctcgg aaatgaacaa gcagaaagag gcgtgattga
    43621 ttgggaactg acagaaaaga aaacatatga actgctgaat aaagtcggtt tgtctatcga
    43681 cccgaatctt ctagtatccc agattggcgt agggcaacag caactagttg aaatagctaa
    43741 agcattatca aaatccgtcc gtctgttgat tttggatgag cctaccgctg cattgaatga
    43801 agaagaaagc gcgaatttgc tgagattgat ccgagagttg aaagagcaag gtgtaacctc
    43861 catcattatt tcacataagc tgaatgaaat cgtggatatc gcagatcgaa tcaccatttt
    43921 acgggatgga cagacgattg agacactaga aaatgaaatg atcagcgaag agcatattat
    43981 tcgcggaatg gtgggcagag atttagttga tcgttatcct gaaagaaaac cggatattgg
    44041 agaagtttat tttaaagtag aagactggac ggtctatcac cctcttgatc acgagcgaat
    44101 cataaacgac cacatcaact tgcatttgaa aaaaggagag attgtaggaa tagctggact
    44161 gatgggagcg ggcagaactg aattcgctat gagtctattt ggacattctt atggaagcaa
    44221 gatatccgga cgtatattaa aggaaggggc agagatatca gttaagaccg ttccttcagc
    44281 cattgcaaac ggactcgctt atgtctcgga ggaccgaaaa tctttaggac tgaatctgct
    44341 gatggatatt cgggaaaacg tgacgctgag cagtttggat aaaataagtc aaaaaggagt
    44401 attagataaa gaaaaagaag taactgaggc agaaaatttc cggaaaaaga tgcgtataaa
    44461 aacaaactcc atccatcaaa ttgtcagtag tcttagtggt gggaatcaac aaaaagtcgt
    44521 tttatccaag tggctgatga cacaacccga tattcttttt ttggatgagc caacccgtgg
    44581 gatagatgtt ggggcaaaat atgagatcta cacgattatc gaagaaatgg cagcaaatgg
    44641 caaagctgtc tgtcttatct cttctgaact tcctgaaata ttagggatgt gtgatcgaat
    44701 ctatacgatg aacgaaggac gtattacagg agaagtctcg cgagaagatg cagatcagga
    44761 agtcttgatg aaattaatga cgaaagaaga ggtgggttaa gttggaacag gcaaaaaatc
    44821 ttacggataa aaaagagaaa aaactaaatt tgaaaagtag agcagctgat ctttttggtc
    44881 gctacagcat ggtgatcatt ttagcgggac tacttattgc gtttcaattg atgacggatg
    44941 gtattttctg gcgtccattg aatataacta accttgttct gcaaaatagc catatattag
    45001 tactagctgc agggatgtta ttagttgtgc tcttaggtca tgtggatttg tcggtagggt
    45061 cagtgatggc gtttgttggt gcaattgcgg gcatgatgat ggtcaatcgc caaatgaacc
    45121 cgtggatgac agttatcgca tgtcttgcag taggcgggct gatcggcgca tggcaaggtt
    45181 tttgggtagc ttatgcaggg ataccggcgt ttatcgtgac tttagcagga ttgctgatgt
    45241 ttcgtggact gacacaagtt gttctaggag gccaatctct agcacctttt ccagctgttt
    45301 tccaaaaaat gtctacgggt tatttaccag acttaagcga aggaagcagc cttcacttct
    45361 tgacattgat tttaggaatg atcatcacga tcgtgttagt tgttggtcaa tggcgaacaa
    45421 gaaatcgtcg gaaaaatcat ttatttgaag tggaatctcc aacagctttc ttggtaaagg
    45481 cggtatttac agcagtcgtt gtactaggaa taacttatat ctttgcctct tatcaagggt
    45541 atccgattat tttgatcatt cttggtttga tcgttgcagc atatgggttt ttgacaaata
    45601 aaacagtagc aggtcgacag atttatgcga cgggcggaaa tcgaaaagcg gctgaactat
    45661 cagggatcaa aacaaagcga atcacgttct gggtattcgt caacatggga gtcatggcag
    45721 ctttagctgg attagtttta gctgctcgat tgaatgcggc aacacctcaa gcaggtacat
    45781 cgatggaact ggatgcaatg gcggcagtat attttggtgg tgcttcgact tccggcggca
    45841 ttggaacaat catgggtgcg attgtcggtg gcttggtcat gggtgtattg aacaatggca
    45901 tgtcgatttt aggcgtcggg gtagactggc agcaggcaat caaaggattg atcttgcttt
    45961 tagccgttgt gctagacttg tataataaga aaaaacgaac aacgtaggag aacgccggtt
    46021 attcagaaaa aagactgtga caagacattt gtcacagtct ttttttcgct aaaagcgaac
    46081 attcattgtt tcgtttgtat agactaaaaa taatatatgt ttttttacca ttcgtataaa
    46141 ttctcttttt gctcttgatt tttttgctta attgagttaa attacatagg gcgctaaaaa
    46201 aagccttgat taaattaata atgttcgtgt tttgctggat gtgaacatca ggaggataat
    46261 gtaatgaaag tatttgatta cgaagatatt caattaattc ctaataaatg tatcgtaaat
    46321 agccgttctg aatgtgatac aacggtcaca ttaggtaaac atacattcaa aatgccagta
    46381 gtgcctgcca acatgcagac gattattgat gaaacaatcg cagaattctt agcggaaaat
    46441 ggttatttct atatcatgca tcggtttgat gaagcagctc gaattccgtt tatcaaaaaa
    46501 atgaaaaagc gtggattgat tacctcgatc agtgttggcg tcaagaaaga ggaatattcc
    46561 tttatagaga agttggcaga agaatcgcta aatcctgatt atatcactat cgacatcgcg
    46621 catggacatg ctaactcagt tattgatatg attcagcata ttaaaaaata tttgcctgaa
    46681 acttttgtga ttgccggtaa tgttggtaca ccggaagccg tccgtgaatt ggaaaatgcg
    46741 ggcgcagatg caacaaaagt cgggattggt ccaggaaaag tatgtattac aaaaatcaag
    46801 acaggctttg ggactggagg ctggcaactg gcagctctta gatggtgtgc gaaagcagct
    46861 cgcaagccga tcatcgctga cggtgggatc agaacacatg gcgatattgc aaaatctgtc
    46921 cgttttggtg cgacaatggt catgattggt tcattgtttg ccggtcacga ggaatctcct
    46981 ggcgaaacaa aagtcgaaaa tggaatcgtg tataaagaat actttggttc tgcttcagaa
    47041 ttccaaaaag gcgaaaaacg aaatgttgaa ggaaagaaaa tctggatcca acacaaagga
    47101 tctttgaaag atacactagt ggaaatgcaa caagaccttc aatcatctat ttcttatgct
    47161 ggaggaagag atctggaagc cattcgaaaa gttgactatg tcatcgtgaa aaattcgatt
    47221 tttaatggag acacaatcta aaaaataaat aaaatattag gatgttgtga aaaagttgtc
    47281 ctgcattaag taataagaac agccaaacaa aaatagttct ttatatgttt tgtttggctg
    47341 gaattattat cgcagataca agcttttgaa catcattatt cagaataagg gactgtgata
    47401 agatttttgt cacagtccct tatgttttgc aaaaaaagtt tttctttttt ctcgtaaatt
    47461 cggtaaaatc aaaagaaaaa atagacaata gaaaagagaa gcttatgtgg gaaaaagtag
    47521 agaaaaaaca aggaccgatt tatcgtcaaa ttatggaaca gattatgaga gaaatcgaaa
    47581 acggaaggat caatcctgga agtcaacttg aatcagaacg aaaactaggg caactttttg
    47641 gtgtgaatcg ttccaccgtt gtccatgcat tggaagagct tagggagctt ggggtactaa
    47701 cgagcaaacg tggcagcgga tggtttgtta atcagactga atgggggaaa ttcgctgttc
    47761 caagaatcga ttggcggcaa atgatctctc ctcgttatga gcagacggac tggtatgagc
    47821 aaaaaataag agaagcaaag cagatccaaa aaacatcgtt tcttgattta tacgctagcg
    47881 agatgccaga tgagcttttg ccgaattttg agtttccttc ttattctctt gaagaaatct
    47941 tagcggaaga aaaagaaatg gatcttttag gctatactcc gttacgtaac aaaatcaaac
    48001 ggtatttgga aagtaaattt gaattggcat tttcccccaa ccagcttctt gtgactggtg
    48061 gcggtcagca agcaatcttt ttgattttac aaacgattct ttcagctgga gaggggatag
    48121 ctgtagagtc accttctttt ttttaccgat tacctctttt caaagcttca ggaacgcgtt
    48181 tatttgggat accgatggat gaagaaggga tcgacttaga aaaactgaaa gaatcgatcc
    48241 ataaaaataa attgaaagca gtgcttatca acccgaattt tcaaaaccct acaggaaaag
    48301 tgatgagtca aaaacgacga gaaaagctag tagaattgtg tcgacagtat cggcttccaa
    48361 ttattgaaga cgatgtattt acggatcttt catttctaaa ccaagaagaa gtccttccta
    48421 tacgaacgat tgatccggat aatgtgttat acgtcggttc gttatctagg gttttaggaa
    48481 aaacaacgaa aatcggttgg gtgataggac ctgagacttt tatctcgcaa ctagctcaag
    48541 cgcaagaaat gatggagttt tcgatgaata tccttacaca aatcacagtg gctaatgtat
    48601 ttaatgaagc aattgatttg aaaatgcaag atgtaagaaa aaagttgaaa gaaaaaagcc
    48661 gactgataag cgcttgggga gattcacaat cgtttttcaa gcttcattca attttaggtg
    48721 gttactatgc ctggattact tgggatggga aaaaactaga ccccgaacta gcagaaaaag
    48781 tagtagatat gggtcttgga attgcaccaa gtctactttt tgggcaagat ataaatggaa
    48841 tcagaatcaa ttacagtagg ctggatgaaa accaaatacc gttgttttat tcaaagatga
    48901 aaattctaga aaagtggtta acagaataat ttcacaaagt aaatagatta aagaatataa
    48961 cagcttggat ttaaatttca agctgtttct tttttttcgg aaaaagaata cgatataaag
    49021 aaactaagaa aaaaccatta tttgtacgtc cgttcacgat gtgtaaataa aataaatgtt
    49081 tgcaacaaaa ctgtataaca ccaacgtttt taaatagaaa cagatggttg taagtttgat
    49141 tagaaaatag aaaaaatgca gatgaaatat aaaacgcttt ccttattgtg attttattca
    49201 ctaatgctgt taatatgcgg attggcataa tttcctttca tcgtgaaaat ttgtgctttt
    49261 agcttgtatt tctcataaat ccatgataat ttattaatga agacggttaa atagtgatac
    49321 agttttattc actgtttcaa tcgcagaatg aagagatttt cttatagatg agagaggaat
    49381 gtgtgacaaa tggcaaacaa aaaagcaccg atcgacttcc aagcactgct agatgaagtc
    49441 aatgcagatt tcccagtata tcaagcactt gatcaagatg gaaacgtagt taacaaagat
    49501 ttagtacctg atttatccga tgatgaactc gttgaattaa tgactcatat ggtatggtct
    49561 cgtgtattag accaacgttc aacagcgctg aaccgccaag gacgcctagg cttttttgca
    49621 ccaactgctg gacaagaggc aagtcagctg gctagtgctt acgcatttga taaagaagat
    49681 gttcttcttc caggttatcg ggatgtacct caactagtaa aacatggttt acctttatct
    49741 caagcttttt tatggtctcg aggacatgct gcaggtaatt cttatccgga agaattgaaa
    49801 gctctaccac cacaaattat catcggtgca caatatgtac aagcagccgg tgttgcatta
    49861 ggtttgaaga aacgaaacaa gaaaaatgtc gtcttcactt atactggtga tggcggttca
    49921 tcacaaggtg atttttacga agcaatcaat ttcgctggcg cttaccatgc aaatgccgta
    49981 ttttatatcc aaaacaacgg gtatgcgatc tctacacctc gtgaaaaaca aactgcagca
    50041 aaaacacttg cacaaaaagc tgtcgcagct gggattcctg gtattcaagt cgatggaatg
    50101 gatccgcttg cagtatatac tgtatctaaa atggcacggg aatgggcgat cagtggaaat
    50161 ggaccagtcc taatcgaaac actgacttat cgttatggac cacatacact atctggtgac
    50221 gatccaaccc gctaccgtac aaaagacaca gatgacgatt ggcagaaaaa agatccattg
    50281 atccgcttcc gtaaatattt gacggaaaaa ggactttggt ctgaagaaaa agaagaacaa
    50341 gtcatcgaag caactaaaga agaaatcaaa gcagctattg ctgaagccga caaagtacca
    50401 aaacaaaagg tttcagattt cttgaaaaac atgttcgaag tatctccaca atcaatcaaa
    50461 gaacaaattg caatttatga agcgaaggag tcgaaataat catggcacaa aaaacaatga
    50521 tccaagcaat cacagatgcc ttagcacttg aactagaaaa tgacgagaat gtcgttgttt
    50581 ttggtgaaga tgttgggaaa aacggaggag ttttccgggc aactgaagga ttgcaggaaa
    50641 agttcggaga agaccgagta ttcgatactc ctttagctga atctggaatc gcaggattga
    50701 gtttcggtct tgcgttagaa ggatttcgtc cagttcctga aatccaattc tttggtttta
    50761 ttttcgaagc aatggacgaa gtagtagctc aaatggctcg tacaagatat cgaatgagcg
    50821 gcactagaaa tctacccatc acaattcgtt cgccatttgg tggcggtgtt catacaccag
    50881 aattgcattc ggataattta gaaggtttga tcgctcagtc tcctggtatt cgagtagtga
    50941 ttccttccaa cccttatgat gcaaaaggac tattgatttc ttctattaga agtaacgatc
    51001 cggttgtttt cctagaacac atgaaactat atcgctcatt ccgagaagaa gtgccggatg
    51061 aagcttacga agttcctttg gataaagcag cagttactcg tgagggaaca gatgtatcta
    51121 ttatcacata cggagcaatg gtgcgtgaag caatcaaagc agcagacaat cttgcaaaag
    51181 aaaatatatc tgttgaaatc attgatcttc gtacagttgc gccattagat gtagaaacga
    51241 tcattcaatc cgtggaaaaa actggtcgcg tagttgttgt ccaagaagca caacgacaag
    51301 cgggcgttgc cgcgcaagta gtttctgaga tctcagaacg cgctatcctt tcattagaag
    51361 ccccaatcgg acgagtttct gcacctgata cagtcttccc atttggacaa gcagaaaatg
    51421 tctggttgcc aaatgcaaaa gatatcgaag acaaagtaaa agaaatcgcg gaattttaag
    51481 aaaagaaggg acgaaacaaa gtcatggctt atcaatttaa attgccggat atcggtgaag
    51541 gaatcgcaga aggtgaaatc gtcaaatggt tcgtcaaacc aggagatacg atcaatgaag
    51601 atgatacatt actagaagtt caaaatgaca aatcagtaga agaaatcccg tcacctgtta
    51661 caggaacggt taaaaatgtg attgttccag aaggtaccgt agcaaatgtt ggggatgtat
    51721 tagtagaaat cgatgcacca ggacacgaag acaatgaagg ggacagtggt gtagccgcag
    51781 aatcccaaac tccagctaaa ccggctgctg aacccactgt tgatacagaa tcagctggat
    51841 cgtcaagcga aggagtcttc caatttaagt taccggatat cggtgaagga atcgcagaag
    51901 gtgaaatcgt caaatggttc gtcaaaccag gagatacgat caatgaagat gatacattac
    51961 tagaagttca aaatgacaaa tcagtagaag aaattccgtc acctgtcaca gggacagtta
    52021 aaaacgtgat tgttccagaa ggcactgtag caaatgttgg ggatgtatta gtagaaatcg
    52081 atgctcctgg acacaatagt gcaccgtcaa ctagtgcgcc atcagctgaa gcaccaaaag
    52141 aaaaagtgga aacatcaggt tcagcaagtg tcgttgaagc tgccgatcca aataaacgtg
    52201 tattggctat gccatctgtt cgtcaatttg cccgtgaaaa agatgtagat atctcacaag
    52261 taactgcaac tggaaaaggt ggcagagtaa caaaagagga catcgaaaac ttcttggcag
    52321 gtggtccaag cagtgcacca gcgaaatcag aagcgccaga agcggcagca ccgaaagaag
    52381 cagctcctgc agcagaaagc aaaccagctg caccagcaaa accattcaag tccaacttag
    52441 gagacttgga agaacgtgta gcaatgacgc caacacgtaa agctatcgct aaagcaatgg
    52501 tcaacagtaa gcatacagct ccacacgtga cattgcatga tgaagtagaa gtgtctaaac
    52561 tatgggataa tcggaaacga tttaaagaag ttgctgctgc aaatggtacg aaacttactt
    52621 tcttgccata tgtcgtgaaa gctttaacag cgactgttaa gaaataccca gtattgaatg
    52681 catctatcga cgatgcaaac caagaaatcg tttataaaca ttactacaat atcggtattg
    52741 caactgatac ggatcacgga ctatatgtac caaatgtgaa agatgcagac cgcaaaggaa
    52801 tgtttgctat tgcagacgaa atcaatgaga aagcaaaatt agctcatgac ggcaaactat
    52861 ctgcagaaga tatgcgcaat ggaacaatta cgatcagcaa tatcggatct gtaggtggcg
    52921 gttggtttac accagtcatc aactatccag aagtagctat tttaggtgta ggaacgattg
    52981 cacaacaacc aatcgtaaat gctgaaggcg aaatcgttgt cggtcgtgtg atgaaactgt
    53041 cattaagttt cgatcaccgt atcgtagatg gagcaactgc gcaacaagca atgaataata
    53101 tcaaacgtct tttagctgat ccagagctat taatgatgga aggatgataa acaaatggta
    53161 gttggagatt ttgctgtaga attagataca gttgtaattg gtgcgggacc tggtggctat
    53221 gtagctgcca tccgcgctgc tgaaatggga caaaaagtag caatcattga aagagagtat
    53281 attggcggtg tttgtttgaa tgtcggctgt attccttcaa aagcactgat agctgcagga
    53341 caccattatc aagagtcact agattctgaa atgtttggag taactagtga aaacgtcaaa
    53401 ctagattttg caaaaacaca agaatggaaa gaaaacaaag ttgtccatac gttgacttct
    53461 ggtgttggtt tcctattaaa aaaacataag gttgaaacaa tcgaaggaga agcgttcttc
    53521 gtagatgatc acacactacg cgtcattcat ccagattcag ctcaaactta ttcgttcaat
    53581 aacgcaatca tcgcaacagg ttcccgtcca atcgagattc caggatttaa attcggagga
    53641 cgtgtgttag attctactgg cggattagca ttgaaagaag tacctaagaa atttgtgatc
    53701 atcggtggcg gtgtgattgg tgccgaattg ggcggagcgt acgcaaactt aggagcagaa
    53761 gtaacgattc ttgaaggctc accacaaatt ttaccaactt acgaaaaaga tctagtaaaa
    53821 ttagtagaag atgatttcaa gaaaaaaggc gtaacagtcg taacgaatgc aatggcgaaa
    53881 gaagcagtcg ataacggtga cagcgtgaca gtgaaatatg cagtggacgg gaaagaagaa
    53941 tccgttactg ctgattatgt gatggtcact gtaggtcgtc gtccgaatac agatgatatg
    54001 ggcttagaac aagcgggtgt cgaagtagga gaacgaggat tgatcacggt ggataaacaa
    54061 ggacgtacga acgtacctaa catctatgcc atcggtgata tcgttccagg ggcggcatta
    54121 gcacacaaag ccagttatga agcaaaaatc gctgctgaag caatctctgg caaaaaagta
    54181 gctgtagatt ataaagcaat gccggcagta gccttcactg atcctgaatt ggcttctgta
    54241 ggtatgacga tcaaagaagc aaaagatgct ggtatcgaag caaaagcata taaattccca
    54301 ttttcaggga acggtcgggc attatcgctt ggtaaaacag aaggattcat ccgtctagtt
    54361 acgacgatcg aagataacgt gcttattggc gcgcaaatcg gtggagtcgg cgcaagtgat
    54421 atggtctctg aattagcttt agcaatcgaa tcaggaatga atgctgaaga tatcgccttg
    54481 acgattcatc ctcatccatc tcttggcgaa atcgtcatgg atgcttcgga attagcatta
    54541 ggtttaccaa tccatatttg atttgaataa tacaggcgaa acgcaactga aaaatcagtt
    54601 gcgttttgtt ttttagaatt atcaataata ttattatgta aacttaaaaa tatgacaact
    54661 tcttggttta ttaccacttc ctatgctaca ctgaagagga atatgaaata ggagagttga
    54721 agatgcaaga atatcagtat ccacttgatt tagattggac aacagacgaa atggtcattg
    54781 taatgaagat gtgggaagat ctggaacgtg cgaatgaaaa agggataaac aatgaagctt
    54841 ttttgaagac ttatcagcag tttaaaactg ttgtcaaatc cattggtgag gaaaaacgat
    54901 tgggacggga atttgaaaaa gcttccggtt attctttata tcgtacagtg cagcaagcaa
    54961 aaaaaaatcc aaacaaaact ttgagaatga acgggtgaga taaatggaac agatgattga
    55021 tcatatcaag tcctggcttg aagaagctgg tgagaaaatc aaatcttctc aacaaacatt
    55081 aacaatctcg caaaaatcaa atcgaacgga tctagtaaca aatgtcgatc gaaacatcca
    55141 gaattttcta atcgaaaaaa tccattcctt tgatccagag gcgaaaatat tggcagaaga
    55201 agaagggtgt aatcaattat cggatctcga tggaagagtc tttatcatcg atcctattga
    55261 tggcaccttg aattttgtga ttgaagggga aaatttttgt attatgctcg ctgtttatga
    55321 atccggcgtt ggaaagcttg gtttcattta tgacgtgatg agaaatgaac ttttttgggg
    55381 tggaaaagga ataggcgtgt ataaaaatga tgagccattg cctagaccag caaataaatc
    55441 cttatcggaa ggcttacttg gtgtgaatag ttatcttttc ggtcataata aatatggaat
    55501 ccgagaaatt gcggaaagca gcatggggac acgtatgtac ggatgcgctg gtcttgaact
    55561 agtggcaatc ttgaaaggaa accacattgc ttatatttca aaccttagcc cttgggatta
    55621 tgcagcggga aatgtcttat tggaagagtt tggtatggta acaagcggtc tttttggtac
    55681 tcctttgaca tttgaaaaaa gggaatacta tttagcaggg acttcttgtg catatgcaga
    55741 aatcgcagac cttttgaaaa aagaaggctg aaaaaaaggt agaaatcatt cacaaaaatg
    55801 ataaaaacga gcaaaagatt aattttctcg aaaaaatgaa aacattttac tatatttcat
    55861 gaaaaaagtc tgctataatt agcagtcgag taaaatttgc cctgtcataa agaaccaata
    55921 aaaaaggagt tagttacatt gaattataga aacgatatcc gtaacgtcgc aattattgcc
    55981 cacgttgacc acggaaaaac aacattagtt gatgaactat taaaacaatc agatacatta
    56041 gacgcacata cgcaattgca agaacgtgcg atggactcaa atgcgctaga aaaagaacgt
    56101 ggtatcacga ttttagccaa aaacacagct gtagactata aaggtattcg cgtaaacatc
    56161 atggatactc caggacacgc ggacttcggt ggcgaagtag aacggatcat gaaaatggtt
    56221 gacggcgttg tgttggtcgt agatgcgtat gaaggaacaa tgcctcaaac acgttttgta
    56281 ttgaaaaaag cactggaaca acatatcaca ccaatcgttg tcgtaaacaa gattgacaaa
    56341 ccttctgctc gtcctgagca tgtcgtagat gaagttcttg aactattcat cgaattagga
    56401 gcagatgatg atcagttaga ctttcctgtg atttatgcat ctgcactaaa tggtacgtca
    56461 agcttgtcag atgatccagc agatcaagaa ccaaccatgg cacctatttt tgatacaatt
    56521 attgaaaaaa tccctgctcc tgtcgataac agcgacgaac cattacaatt ccaagtttca
    56581 ttacttgact acaacgatta tgtaggtcgt atcggaatcg gacgtgtatt tagaggaaca
    56641 atcaaagtag gagaccaagt agcattaatt aaattagacg gaacagttaa gaaattccgt
    56701 gtaacgaaat tatttggttt ctttggacta aaacgtctag agattcaaga agcaaaagct
    56761 ggagacttga ttgctgtctc aggtatggaa gatatctttg tcggtgaaac agttactcct
    56821 gtggatcatc aagatgcgtt acctatcctt cacattgacg aaccaacatt gcaaatgact
    56881 ttcttagtta ataattcacc atttgccggt cgagaaggta aattcgtaac cgctcgtaag
    56941 attgaagaac gtttgatggc agaacttcaa acagatgtat ccttacgagt tgaaccaaca
    57001 aactctccag atgcatggac agtttctggt cgtggagaat tgcatttgtc tatcttgatt
    57061 gaaaacatgc gccgtgaggg atacgaattg caagtatctc gtccagaagt tattgaaaaa
    57121 gaaatcgacg gtgtaaaatg cgaaccgttt gaacgcgtgc aaatcgatac accagaagaa
    57181 tatatgggta gtgttatcga gtccttgagc ttacgtaaag gtgaaatgca agatatggtc
    57241 catacaggaa acggacaaat ccgtttgaca ttcttaacac ctgcccgcgg tttgattggt
    57301 tattcaactg aattcctttc aatgacacgt ggttacggaa tcatgaacca tacttttgac
    57361 caatatctgc caatgcttcc tggtcaaatt ggcggacgtc accaaggggc gcttgtttcg
    57421 atcgatacag gaaaagcaac gacttattct atcatgagta tcgaagaacg cggtacagtc
    57481 ttcgtagaac caggtacaga agtatatgaa ggaatgatta tcggggaaaa cagccgtgat
    57541 aatgatttga ctgtcaacat cacgaaagca aaacaaatga caaacgtacg gtctgctact
    57601 aaagaccaaa catctgtcat caaaaaacca aaacaattga cgttggaaga atctttggaa
    57661 ttcttgaatg atgatgaata ttgcgaagta acaccagaaa gcattcgctt gagaaaacaa
    57721 attttagaga aaaatgctcg tgaaaaagca tctaaaaaga aaaaataatc tgtaaaagga
    57781 tgaagagaga aaccagcttg ttataaaaaa tagctggttt ctttttttgt ccaactcttt
    57841 tctgtggaga agtcatcttt gtcaatggac ataaattcag aaaatacgcc gaaagacgtt
    57901 taaaagactt ttaaaaaact tatttctaga gagtttttgt ttcataataa gataatgttt
    57961 cacgaaagga gatcaacttg tccttcgaag aaaatcgaag taaaatggca agagaaagga
    58021 gcgggaagat gaacgactta ttaaaacaat actttggcta tgatgagttt agacctggtc
    58081 aaaaagaaat tatccagaaa gtcattgatc aggaaaatgt attaggaatc atgcctaccg
    58141 gaagtgggaa atcaatctgt taccagcttc cagctttact attagatggg cttactgtgg
    58201 ttgtgtcccc tttaatctct ttgatgaagg atcaggtgga cgcggcgaat caattaggta
    58261 tacccgccac ttttatcaat agctcgttag atggttacga aacagctaga cgcttccaag
    58321 aaatcgatag acagcagtac cgtttacttt atatcgctcc tgaacgtttt atcatgccgg
    58381 attttatcca agcaatgaag cgatggaacg tccgtatgat cgctattgac gaggcacatt
    58441 gtatctctca gtgggggcat gatttccgcc caagttattt acagatggcg aaccagctag
    58501 atcaactgcc aaatcgtcct gtaattgttg ctttgacagc tacagcgact gtgcaagtag
    58561 ctgctgacat aaaaagactt ttaaaaattc cagaaaacaa ccatattcag actggttttg
    58621 aacgagaaaa tctacgattt caagtaatta aagatcaaaa aaaagaacaa tatctaatcg
    58681 aatatttaaa gatcaacaaa aatcaatctg gtatcattta tgcagcaacg agaaaagaag
    58741 tagaccgtct ctatcatttg cttaaaaaat tcgatttttc cgtgggtaga tatcatggtg
    58801 gtctaaatga gaatgagcga acagaaatgc aagaagcctt tttatacgat cgcttgcagc
    58861 tgattgtagc gacaaatgca tttggtatgg gtataaataa aagcaatgtc cgttttgtta
    58921 tccattatca aattcctggc tctctagaag catactatca ggaagctggt cgggcgggaa
    58981 gagatggtct ttccagtgaa gccatcctgc ttttctctcc tcaagatatc caagtccaaa
    59041 agttttttat ccagcagtcc caaagagaag aagggcaaaa gcaaaaagaa tatgaaaaat
    59101 taaaagcgat gacagaatac gtgtatattg agtcctgtct tcagcaatac atcctaaact
    59161 attttggcga gacaagcagt ccgtgcaacc gttgtggtaa ctgtttagat gacagagaaa
    59221 tagtagaagt aacgacagaa gcacagatgg ttctttcttg cttaaaacgt atgggtgaga
    59281 actatggtaa acaaatgctg atgaaagtct tagcaggatc gaaagaacaa aagctgcaag
    59341 ctttaggttt tggacattta tctacctatg gactgatgaa aaaccaatcg caaaaagaaa
    59401 cgatgcagtt aattgaatat ttgatatcga atggctatct tctgaccatc aatggtgagt
    59461 atcctgtttt gaaagtaaca gaaagaggga tacaagtatt gaaaggacaa gaatctgttt
    59521 atcgaaagga acccaagaaa gtccagcagc tatcggatga agaaaccgat acactatttg
    59581 aagtgctgcg ggaactgcga acggatctag catcagaagc aggcgttccc ccgtatgtcg
    59641 tattttcaga ttccacattg aaagaaatga gccgaatacg tccatcaagc agattggaga
    59701 tgcttcagat aaaaggagtt ggccaaagca agcttgataa atatggcgaa gcctttttat
    59761 ctcggataaa aaatgcggac tctaacgttc tggataagta gaaagaacga atacgtaaaa
    59821 atgaataaaa acaactggtt aaatctgttt tttttgctcc ttatgaaaat caaatatgtt
    59881 ataattaagg aattagaatg ggaggtaagc acagatggat tctttgtcga aaaaacttgc
    59941 gatccaagta ttaaatgatg aagcagaacg gatcaaacga ttaatccgaa atcaaaacaa
    60001 cagtctctgt atctcacaat gcaaagcctt cgaagaagtg gtagatacac agatgtacgg
    60061 cttttcccgg caagtcggtt ttgctgtccg tataggagta atcggaaaga acgagggcca
    60121 gctgatgtta agtgagctag aacgagaatt gaatcagtta tatagtgagg tttaccaaga
    60181 aatttatgat aaaaaagaag ttggcaagga ggaatagact tgcctaagaa agtgaaaaaa
    60241 aggcatctat tagactatag catcttgatt ccctatttaa ttttatgtgt attgggattg
    60301 atcatggtat atagttctac gtcgtatcta ttattagaaa acggacaaaa tccgtccgca
    60361 tcagtcatta accagagtat tttttgggtg cttagcttga ttgctatcgc actactttat
    60421 aaaatgaaaa cagatgtttt gaaaaaccag cgtttgatca tggcagccat cgcagttttg
    60481 acgattttgc tgctgattgt tgtgtttttt ggtaaggaga tcaatggggc gaaaggttgg
    60541 ctgcaaattg caggattctc gatccaacct gccgaatacc taaaaatcat ttctatctgg
    60601 tacctgtctc tgactttatc taaaagacaa aacagtgtac aaaaagattt tcttgggact
    60661 gtgaaacgtc cacttgcaat ggttatcgga cttactgcat tagtcgctat tcttcccgat
    60721 tttggtaatg cggcagttat ctttttgatt attttggttc tgcttttagc cagcggagtc
    60781 aattatgtgt atactttgat tgtaggagta ggaggctttt gtctaagtac ttttacgatc
    60841 tggctgatca atatcacaaa cggaaagatc ttacccggac gtttacagta tatctataat
    60901 cgatttgcta tttaccaaaa tcctttctca gacgaattaa ataaagggca tcaactagtc
    60961 aacggctact atgccatgtt caacggagga ctatttggca ggggattagg taacagtatc
    61021 cagaaaaaag gatttttaca agaagcacaa accgatttta tttatgcaat cgtagtggaa
    61081 gaactgggag tgattatggg gattttgata ttagcgttgc tattctttat gattgtgcgc
    61141 attgtccttg taggtatccg ttcaaaagat ccgttcaatt cgcttttgtg cattgggatc
    61201 ggcgcaatgt ttttgatcca agtatttgtc aatcttggag gaattactgg cgttattcct
    61261 ttgacaggga tcacgttccc atttttaagt caaggaggct ccagtttgct gatgctttcg
    61321 atttgtgtcg gctttgtcct caacatcagt gcggatgaaa aacgcaagag cttaggttta
    61381 taataaaaaa agatgtagga gtggttcgat gaaaaaagtt ttagttgcta acaggggtga
    61441 aatcgctgta cgtgtatttc gtgcttgtac agaattagga attaaaactg ttggaatcta
    61501 tgcagaagaa gatgaatatt ccgtacaccg tttcaaagcg gatgaagcat atttagtagg
    61561 acaaggaaaa aaaccgattg atgcgtatct agatattgaa gggatcattt ctatcgcgaa
    61621 agaatgcgga gctgacgcta ttcatccggg ttacggtctt ttgtcggaaa acttgaattt
    61681 tgcgcaacgg tgcgaagaag aaggcatcat ttttgttgga cccaaactgc atcatttaga
    61741 tatttttgga gataaaatca aagcaaaagc tgcagctatc gaagcgggga ttgcttcgat
    61801 tccaggcaca gatggaccaa tcgcttctat agacgatgcc ttggagtttg cgaaacaata
    61861 cggttatccg attatgatca aggcagctct aggcggcggc ggacgcggca tgcgtgtagc
    61921 tcacgatgaa aagagtgcaa gagagggcta cgaacgtgcg aaaagcgaag caaaagcagc
    61981 ctttggtagt gatgaagtgt atgttgaaaa atacatcgct aatcctaagc atatcgaagt
    62041 acagattctc ggggatacgc atggaaacgt catccatctt tttgaaagag attgttctgt
    62101 tcagcgccgt caccaaaaag tagtagaagt agcgccttgt gtctctatga atgaacagca
    62161 acgtcaaaaa atctgccagg cagctgtcca attgatgaaa tatgtcgggt atgtcaacgc
    62221 aggtacagta gaatttcttg ttgaaggaga tgatttttac tttatcgaag tcaaccctcg
    62281 cgtccaagtg gaacatacga tcacagaaat gattacagat attgatatcg taacaacgca
    62341 actgttgatt gctcaaggtt tggatctgca taaagaaatc ggattgcctc agcaagaagg
    62401 aattaaatta aatggttcag ccattcaatg ccgaatcact acagaagacc cgttgaataa
    62461 ctttttacca gacacaggga aaatcgatac gtatcgttca cctggtggtt ttggcgtacg
    62521 tctggatgtc ggaaatgctt acgcgggcta tgtagtgaca ccgtattttg attcattgct
    62581 agtaaaagta tgtacgcatg gtgctacctt tgaaacagcc attcagaaaa tggaacgttg
    62641 cttgaaagaa tttagaatcc gtggagtgaa aacaaacatt ccatttatgc tcaatgtcat
    62701 cacacatcct gaattccaat caggaaatgc aaaaacaacc ttcattgata gtacagcaac
    62761 attatttgaa tttcctcgac tacgagaccg cggaaacaaa acgatgaaat atatcggtga
    62821 aattactgtg aatggttttc caggtatcga aagtggcgaa aaaccatttt atgaagaacc
    62881 acgtatgcct aaagatctaa tcacaagaac tgattacgta acggctaaga atgtattaga
    62941 tgcgaagggt gccgatgctt tggtcgaatg gatcaaagga caggaaaatt tgttgttgac
    63001 ggatacgaca tttagagacg cccatcaaag tctgctagca actcgtgttc ggacaaagga
    63061 tttcaagcag attgcacgtt tgactggaga aggtcttcct gaactctttt caagtgagat
    63121 gtggggggga gcaacatttg atgtggctta ccgctttttg aatgaagatc cttggcaacg
    63181 gttgagaaaa attcgttctt taatgcctaa tacgttgctg caaatgcttt tcagaggttc
    63241 aaatgccgtt gggtattcta attatcctga caatgtattg gtggaatttg tcaaagaagc
    63301 agcagcgcaa ggaatcgatg tatttcgaat ctttgatagt ttgaactgga ctccacaaat
    63361 ggaaaaaagt atccaagctg tacgggatac tggtaaaatc gcagaggcag ctatttgcta
    63421 tactggcgat atcaacgatc caagtcgggc aaaatacaat gttcagtatt ataaagacat
    63481 ggcaaaggaa ctagaacaac tgggtgcgca tatcattgca atcaaagata tggctgggct
    63541 gcttaaaccg caggcagctt atcgtttgat tagtgaattg aaagaaacga cagatctgcc
    63601 aatccatctg catactcatg ataccagcgg gaatggaatc atcacttatt ctgctgcttc
    63661 aaaagcagga gtagacatcg ttgacgtggc aatgagtgca atgagtggga atactagtca
    63721 gcctagcatg agcagcttgt attatgcact ggtcaatggt ccacggctgc cagaaatcac
    63781 gattgaaaat gcacagaaat taaaccatta ttgggaagat gtgcgcatgt attacaaacc
    63841 gtttgaaaac ggcttgaatg ctcctgaaac agaagtatat atgcatgaaa tgccaggagg
    63901 acagtattcg aatctacagc aacaggcaaa agctgtcgga ttaggtcatc gctgggatga
    63961 aatcaaacaa atgtatcata ctgtcaactt gatgtttggc gatatcgtta aagtaactcc
    64021 atcatctaaa gtagttggag atatggcact atttatggtc caaaatgatc ttacagaaga
    64081 agatatttat gaaaaaggcg aaacactaag tttccctgaa tctgttgtga ctttcttcca
    64141 aggagaacta gggcaacccg ttggcggatt tcctaaaaaa ttgcaaaaga ttattcttaa
    64201 aggcagacct gcattgaatg aacgtccagg tcttttggct gaatcagtcg acttcaacga
    64261 agtaaaaaaa gaattggcag aaaaaattgg ctatgaacca aaacaagacg aagtattaag
    64321 ctatttgatg tatccgcaag tctttttgga ctatcaaaaa gcatataatc aatttggcga
    64381 tgttacatta ctggacacac caacattttt ccaaggtata cgtttgggtg aaacaatcaa
    64441 tgtacaaatc gaacgcggaa aaacgcttat cattcgttta gatgaaatcg gagaacccga
    64501 tatcgaaggg aatcgcgtac tgttcttcaa tttgaatgga caaagacgtg aaatcactat
    64561 caaagataat tcgatcatca gtacggtcca aacccgattg aaagctgaac cgacaaaccg
    64621 agaacaaatt ggagcaacga tgtctggttc tgttttggat gtattagtga aaaaaggcga
    64681 taacgttaaa aaaggtgata cgttgatgat tactgaagcg atgaaaatgg aaacggccat
    64741 cgaagcacgt tttgacggag aagtcgcaca tgtatatgtg tcttcaggag acactatttc
    64801 gtctggtgac cttttgattg aagtgactga gaaataataa gcgaaaggtg gggaaacatg
    64861 aaaagactgg gtttgttttg gctgattctg ctattagtta ttgtggcatt ctacatggaa
    64921 ccagtcttgt ttccgccaaa acttgaagtg aaggaaaact ctgatcaaca aatatcaaac
    64981 caaatgacaa cgtggaaata ccaggagctt aaagcaactg gtttttctac ttatatcgga
    65041 aaaccgatcg atcagctgga aaaggatttt ggccaagcct atgatcgatt aactagcgga
    65101 tttggttttg aaacaagata ttatgaaaat aaagctagtc atctcacatt tgaagcgaac
    65161 atccaagaca gcagagtcac aactgttaaa gtactgcaaa cagggcctgc tgatatcgcg
    65221 ccgttttatt tagggatgac gatgcaagat cttacgaaaa tcactactat ctatactaat
    65281 ttcacttttg agtaccatga tacagaagtt ggaatcgaac taatggaaga ggatatgaat
    65341 tatcgtccgc taattgcttt tgataacgac acttttgcta ttttattttt tgatcaaaca
    65401 acaaacggcc tattttcagt tgtgtattta gataaagata gtcttttgaa actattgcca
    65461 tatcaagtgt ttggtgaagg ccttccacat tatcaagcag ataaatcggc tgattgggaa
    65521 tcaatcaatc gcgttaaaga acgaaaaagt acgactttat taaatatgct tagaagagaa
    65581 gacgaacttc ccatatacaa tcaaacactt gcctttcaaa accacagtca gctgctacta
    65641 catgattttt tgacaaggcc tgaggaaata ttgtcagagg aacgtatggc tgattggcaa
    65701 aaatcgctag gcagtgctca aacgacagtg aaattctcac tgacgaatga tgaattggag
    65761 aagttaatca gtaaacaaaa attagaaaat actagtgggc tatttattca tccggcgatt
    65821 gacgctactt tttcgttttt atattggtac agcgatcctt acaaccatga ccgtttcatg
    65881 gacccgggaa cggattctgt aggcattgct ttttctaaag aaaatatgtt agtcttattg
    65941 caagaagaaa acggagaaag tagtgatagc agtgatcgtt aacgaagagc tgtttcaact
    66001 ggaggatcaa tgcctccaag tcgctgaaat gataaaaaag agtaaaacga tggcttctta
    66061 tcttgaacat aaacagtcaa tggaagaatc tgcaaaagtt tgccagttga aagaagcgtt
    66121 cttgtctaag aaagaagcat ttgaaaatgt agcggcatat ggtgagtatg cacctgatta
    66181 tcgtgaaaaa aaacgagctg ttcgaaaagc aaaaagacag cttgatatgg atgagcatgt
    66241 tgcagctttc cgatatagtg aaacacagct gcaaagtctg ttggatcaaa ttgtccaagt
    66301 acttgccgaa gaagtttcta atgaaatcaa agtagatgca ggtagcccgt tttttgaaac
    66361 gaaaaaacac tttggatgcg gaggtaattg tcatgcaatt agacaatagt gaatttgaaa
    66421 taacaaaacg acgcgggctg atcgtatggg tctacagctt aaaacaatta aagaatctga
    66481 aaaagttcgg cttgttgcat tatgtctcaa gaagaatgaa atatgtcgtg ctttacttaa
    66541 atgaagagac attggaagaa acagaagaac gaatccgtaa attacatttt gttcgaaacg
    66601 tagaacgttc ttaccgaccg gatatcgaaa tgaattttgc cgaaaaaata ggaaacaaaa
    66661 cagtattaaa agacgaaggt ttcgaaattg aagagctaaa tacagaaatc cgattagctg
    66721 aacatcttta aaaatctctt atgagcagtt tttaaataaa aaataacttg gataacgatc
    66781 gatttttgat cattgtccaa gtattttttt ggtatactag taccagtacc atttctaagg
    66841 agtgagtaga tgcggataat atcaggaaat tatggcgggc gccgtttaaa aagtttagca
    66901 ggggcgaaca ccagaccaac tacagataaa gtaaaagaat ccatattcaa tatgattgga
    66961 ccatattttg atggagagac agtattggat ctgtttgcag gaagcggtgg tttagctatc
    67021 gaagcagtat ctagaggctg cagtcatgcg gtatgcgtag acaaaaatta ccaagcgcta
    67081 aaaatcatca aagaaaacat cgaaattacg aaagaaccag agaaatttac cacaataaaa
    67141 cttgatgcgg acaaagcaat cgaacggcta gcagcggaga aacaacaatt cgactacttg
    67201 tttcttgatc cgccatatgc aaaacaaaaa ataatcgatc aaatccataa aatggaagaa
    67261 ctgggacttt tttctaaaac cgcagttatc gtatgcgaaa cggataaaac agtcgaattg
    67321 ccagaaactg tggctggatt ccatcaaata agaaaacaga tttatggcat aacggccgta
    67381 actatctata gaaaagaggg aaatcaatga aacgtgcatt attcccagga agttttgatc
    67441 cttttacaaa aggtcactta gatacggtgg aacgtgcggc taaattattc gatgaggtag
    67501 taattggtgt ttttatcaat acttcaaaga aaagtttgtt tcccccagaa gaaagaatga
    67561 cattgatcac aaaagctgtt tctcatcttc ctaatgtaaa agtcatgcat caagaaaatc
    67621 aattgacggt agaaacagca aaagagattg gtgcagatgc gttgatcaga ggcatacgaa
    67681 gtatcaaaga ctttgaatat gaacgagaga ttgctcagat gaatcatcat ctatatgatg
    67741 aattggaaac tgtcttctta ttagcaaaac cagaatatag tcacgtgagt tccagtattt
    67801 taaaagaagt actgcacttt ggcggagatg tgagcagcta cttaccgcca gtgatcaacg
    67861 aagctttagc tggaaagcgt gaatcaaatg aaagctaaac aatggttgaa aacagtactg
    67921 attatcatat ttggaatgtt gatcattgga tttgtagtag ttcccttgcc gtattatgta
    67981 gaatcaccgg gagccacgat cgatctgaaa gaactaatta cggtcaatga taaggaagat
    68041 aaaggttctg ggtctttctc tcttacctct gttggtatca ggcaagctac aggtttctta
    68101 gctttaaaag ctaaaatgac cccttttgaa gaattgatca gtgaagaaga attgactggt
    68161 ggggcgacaa atgaagaata taatcaaatg caacagtatt atatggattc ttcccaaaat
    68221 gcagcaatcg aacaagcgtt aaaacttgca gacaagcctt ataaaatgga attcaaaggc
    68281 gtatatgtca tgagtgtaga gaaaacatcg aatttctttg gcaagctttc agttggagat
    68341 acagtaacaa aagtagacgg gaaaagcttt caaagtacag aagcatttat ggattatgta
    68401 aaaagccaaa aagttggaca aacaatcgaa atcagttatt tgcataatgg tgaagaaaaa
    68461 acagcttctg gtgatctgat cgagttacca acagataaaa aggcaggaat aggtatcacg
    68521 cttactgacc ataccgagat cgaatcagat acagatgttc gtattaattc tggctctatc
    68581 ggtgggccat cagcgggatt gatgttcact ttagaaatct atgaacaagt cactggtaaa
    68641 aacttgcgac atggtaagca aattgcagga actggaacga tcaacagtga aggagaagtt
    68701 ggccgaatcg gaggaatcga taaaaaagtg gcaagtgcgg ataaagctgg cgtagagatt
    68761 ttctttgcac cagatgatac gatttcagac gatgttaaga aagaatatcc tgaaataaaa
    68821 accaactacg aagaagcaaa agctgccgct aaaaaattga attcctcaat gaaaatcgta
    68881 ccagtaaaaa cagtacaaga agcgcttgac tatctagaga aaatgaaatg aaactaaata
    68941 attaaagagg ggttgtgaca cgagttctgt cacaacccct ctttttcgtc aaaaatcttc
    69001 acgataaaaa taaaaacaaa agaaaaaatt gacgtaatta gatgttgaag ggacgatttt
    69061 gccagagctc actgtttctt caattttaaa tgaaaggagt aatgaatgat ttttactggt
    69121 cattctttga aaaaagaaca atgatagaaa aaatcagcaa gaaaatacta gcttcaccca
    69181 aattgatcat ttggatgtct atgatagttc ttatcttttg tatcgcaagt ggttttttat
    69241 tatcaaattt gctattttat agagaaacag aagagactgc tgcaaaagaa atactttctt
    69301 cgtttagttc cagtggagaa gatccatcag ctgaaggaaa cgatgtagaa gaggatgctc
    69361 gtccaaaggt catgtacacc gatatcaaag gaagtgtgaa ggagcctggt atctattcct
    69421 tttcttcaga agaacgggtc tatgatgtac taaagcgtgc aggtggatta ttagaagaag
    69481 cggatagcga tcgaatcaac ttttctgcga agatagaaga tcagcaagtc ctatatatcc
    69541 ctgctgtagg tgaagagctg ccagaacatc ttgatcagtt ggcatcctcg gaaggaaaac
    69601 agcctacagc agattccgag cctcccaaaa taaatatcaa tacagccact ccatcagaac
    69661 ttcagcagat tcctgggatc ggatcagtca aagcgcaaga aatcattcga tttagagaag
    69721 aaaacggatc cttccagaaa gtggaagacc tgcaggagat ttctggtatc ggtgaaaaga
    69781 cagttgaaaa actaaaaaac ttcgttacaa ttaaatagaa tgattcaaaa tcgactggca
    69841 cgagcaataa atggacgcta atggatacta agaataatcc aattctaaga gcttggcagg
    69901 acgaggaggt agtatttttg gataggaaat agcttgattg ttcgcaaaga aacattaaaa
    69961 aaaccaatgc tgaatgtcta tctccaaaat aaaatatctg ggattcatat tatgaatacg
    70021 gctgtcagcg gcaataacag tcaagctcta cgagaacgct ttgccaaaga tgtacttagc
    70081 tatacagcag ataaagtatt tattctcatt gggacgaatg atctagcaga gcataaacaa
    70141 ctttctaaag aaacgtacca aaaaatctgc agtggatgat agttcagctg aaaaaagact
    70201 atagttctga tcatgctttc tttatcacgc caccagcagt cgatgagaca aaacaaaaat
    70261 atcggaataa caagttgatc aaagaatata tctctgttct cacagaagta gcaaaacgcc
    70321 atgattgtga agtatcgatt tttatacgga atttcttgaa caaatggatt cgaagaattt
    70381 ttataatggg ctaatggatg acggacttca tttcggcagt gaagggtagg atcttttgtc
    70441 agacaggatg attcgttata tttaaagaat attttgttta agcaatgagt actttttaat
    70501 caacttgaaa aaacggagga atataaaaca tgttagaaaa atcttcaaaa gcatgcgata
    70561 cgaataaaga aaaagttact gataagtcac ataatgaacg cattccttgg gaccagtact
    70621 ttatggctca ggcagtactg ttatctttac gtagtacgtg tacacgttta gaagtaggag
    70681 cgacactcgt tcgagaaaaa aggatcattg ctggcggcta taatggagca gtcagtggag
    70741 atgtccactg catagatgaa gggtgttacg tcgtggatgg acactgcttg cgaacgatcc
    70801 atgcagagat gaatgcactc ctacagtgtg caaaacttgg tatcccgacg gaaggttcag
    70861 aaatctatgt cacacatttt ccatgtttgg cctgtacaaa ggctttgttg caagctggtg
    70921 tgaaagggat caattatctc catgactatc gaaatgatcc ttatgcccaa gcgttgatcg
    70981 aacaattagg tgtatctgta caccaagttg ctttagactc acagcatttt tcaaaacttc
    71041 aaaatgaatt aacaggaaaa catgtctagc gttttagaaa ggcatgttcg aaatcggttg
    71101 atttttccgg caattacgtc gatgattatc tgtttgttgt attacactga caattggggt
    71161 tatcgtttgc ttcttgccgg aattttttta tggttttcgc taaaagaagg acgttttatc
    71221 gcgtacttgt gtattttgtg tagcataacg gtatccattt cttataggct acaagagtat
    71281 tcatttttag aggaaaaaac aacatctgcg caaattactg tatttacaga tacgattcgt
    71341 gcaaatggta attttttgac aatggaagga aggttatcag agaataaaca aaagctccag
    71401 ctttcttatc aagtaaacac agaagcagaa ttgaaaacat ggcttaactt ccgaggaaag
    71461 ggaatagaat tgactgctga aggcgagttc atctctccag caaaaaagcg gaatctttat
    71521 aattttgacc aagaagctta cttcaggaac catagaattt ctggacggtt ccaaattcaa
    71581 aagattgaac agatcaccat gcaaaatcac tggcgaaact ggcttcagag aaaaagagga
    71641 tcttttatct cctttgtcca atctgaattt ccgcaaaaaa caagtgtata tattaattct
    71701 ttattatggg gctataaaga tgcaggattc agagaaccag aagaaatttt tagggagagt
    71761 ggtttgctgc atctgttcag tctatcgggt ctacacatcc aattttattt agggtggctg
    71821 tattatttgt ttcgacgtat cggatggcca ctacacgtca gtattattcc gttgagtcta
    71881 ctaactatct gttatgtttc tattgcagga agttctattt ctgttttgcg tgctagtttg
    71941 ctgtttttat tgcgattgct agtcaaattg ctgaataagc attattccac catggactta
    72001 tttgcagttg tcttttggct tcttttacta tttgatcctc gatttctttt tcatgcgggt
    72061 ggacagctta gttttttcat gagttttttg tttatcctga tttcttttga tggagattgg
    72121 ttgaaaaaaa cggcctctca cgtcctgttt actatgatca cgatgccgtt gattgtatgg
    72181 catttttatg agtggcctat tttaggtagt ctttttacat tactgattgc accggtattc
    72241 aagtttcttt ttcttcctgg tgtgttattt ctcacactct tcaatcgctg gctgccggaa
    72301 actttacttt tgctgataga agagggatta atcttatttg agcgaataat cgatttttct
    72361 tcagggtcgt ctctcattat aggacgtttg ccccttgtgc tatctgggat gtatattttc
    72421 ggattactga tttgtatgga taggttgaaa gaacaacctg tgaaacactt gttttatgtt
    72481 ggtctttttt cttttatttt tttgactttg ccatttttac gcttttcttc aacgatcgct
    72541 tttatcgatg tcggtcaagg agacagtatc tttttgcaaa gtccttttcg aaaagaaacg
    72601 attttgatcg atactggagg tcagttacac tttgaaagag aaaagtgggc gcaaggtatg
    72661 atacgtcctc ctgctgaaag aaatatcgtt ccatatctaa aaggtcaggg gataagtgta
    72721 atcgataaac tcatcttgac acacgacgat acggatcatg tgggagaatt acccacgtta
    72781 tctcagcatt ttactatcaa aaaaatttat atcggttggg gcgctggacg aaatgagcca
    72841 ttacaaaggc atttatctga agctcaaaaa aatggtactg agatcattga aatcaaacat
    72901 ggggacagga tcagcggtta ttatgatctt tatgtattga ctccttttga aaagggagag
    72961 ggaagaaatg aagattcgat tggtctatgg atggaatata acaataggcg ctttttattt
    73021 ttaggagatt tgaatcaagc aatggaaaaa caattgcttt tgatttatcc taatctgaaa
    73081 gccgatgtag tcaaattagg tcatcacggt agccgtacgt caagtaacac agattttctt
    73141 tcccatattg aagcaaaaca tgggattata tcctgcggcg taaataatcg ttatggtcac
    73201 ccgcacagcg aagtattgga gacactagaa gaaaatcaga taaaaacatg gcgaacggat
    73261 caacaaggaa tgatcaccta tcgctggcat ccagtttttc atcctcatgg gctagtggaa
    73321 acaatgatag actagtaatt ctcatctgct catggtagga taatttttga aagtggtgag
    73381 taatttgagt atacaagcag agttacaaaa aatacgtaaa gaaaaacttg catcttgtta
    73441 cttgatttta ggaacagaaa agtttctcca agatcaagtt cggacagaaa ttgtcaaaaa
    73501 aatccaatta gagggcgaag atgacttaaa ttttttaagt tttgacatgg aaaatgcaag
    73561 tttagatgag gtagtagctg aagcagagac gttgccgttt ttcggagatc aacggttagt
    73621 attcgtagag aatccttatt ttttaacagg tgaaaaagta aacaatggaa tcgaacaaaa
    73681 tactgattta ttgacggctt atttgaaaga accattagaa tcgactgtat tagtattctt
    73741 tgcgccatat gaaaagttgg atgaacggaa aaaagtaacg aaacaattga aaaaaacagc
    73801 aattatcatc aatgtccaac agttgaatga aaaagaagta cgtcaatatc tgatgaatac
    73861 cttagagaat tcctcaatca aaatggaacg aagtgcaatt gatttattct tgaggttgac
    73921 cgacttagat ttatccaaaa tgatgagaga gttacagaaa ttggtccttt atggacaaaa
    73981 tcaacagcaa atcacggtaa gagaagtaga agaattagtt cctaaaacgt tagaacataa
    74041 tatttttgac atgacccaat atattttaaa agggaagacg gaacaagctt tgcgtttata
    74101 cgaagattta gttatgcaag gggaagaaac aatcaaaatt aatgcgattt tgctttctca
    74161 attacgttta tttttacaga caaaatttct tgtaaagatt ggttatcagc aggcaaatat
    74221 tgctgaaaca ttgaaaatcc atccatatcg tgtaaaactt gccatgcagg aagtaaaaaa
    74281 attcgatgaa catttgctgg tacagttgtt tgatcaatta gttgagatgg attatcaaat
    74341 caaaacggga caaatcgaaa aagaattaag ttttcaacta ttcgttttgc gcacagggca
    74401 gttgttaaga aatcgataag aagaaagacg agggcaaagc atgcgggaag gtcgtttgtt
    74461 tttgtccttt ttttgacaaa taaaaaaatc ggccgaagcc gattctttta tttagcgatt
    74521 tttttgctta aacgagattt gtcgcggtta gctttgtttt tgtggattag accttttgat
    74581 tcagccatat caatagcttt aacagcttct ttatataacg catctacgtt gtcagcacct
    74641 gaagctacag catcttcaaa ttttttgatt gcagtacgca tagcgcttgt ttgagatgaa
    74701 tttttcacat tagcgttttc gcttgtacga acacgtttga ttgcagattc aatgtttggc
    74761 attagtttca cctccgataa cttaagttct tacgcgtgtt accgcataat tcaacattca
    74821 ttattatacc taaaggcagc gtgctttgca atatgaacat gacaagtttt tttccttaac
    74881 agtcttttat taggattttt tttcagtaaa aacggatagt acaagctgaa aaaaatcaaa
    74941 aagacgctat tgtgggaggc aatagcgtca aaccaaacta gatttttatt tatctattta
    75001 aacaaagttt gaatgggaat gtttggtact aagttattat ataacaaaga gaaccgtttg
    75061 caaagttttt tttgaaaagg gatacgattc cctgttgttc tttgtttttc tattaagaaa
    75121 ctgcagttat tttataacca gtatcctttg atcagtaaag gctattctgg tgtaccgatt
    75181 attttaatgt attcatcgat attttttatc aacatttttt ttatgaccaa ctggttccga
    75241 cggttccatt tgccacttac ttccagcaca tatttattta ggggcaaacg taagatatat
    75301 tttgccaaat agcgatcttt aagcaggcca ttgatcacac ggtcctcaag ctgcaagttg
    75361 atcccagtca gcatcattgg ctgttcttgt aaaacgtacg tatcaattaa aagaccttca
    75421 aaagtttcca caagcgtctt cctttctttt caaagtaacc tgaaaacagg cactaattct
    75481 tccattttga tattcgttga agtggatgcg atcattcttt cttttgtcca ctgtaatcta
    75541 gtataacaaa aaagagcaga agagccaaaa agaaaaaaga gcatcgaatt ctataggaag
    75601 tctcattggc acggcctaaa ttattacaaa acattgatta aaaaaagccc ctgcatcgca
    75661 ggagcatccc ctatatcgtt ttaataggtc aatcaaaaag cagtatcaaa cacattttgt
    75721 atcaaatcag gaaataatag ataagctaag cccagaatca aaagtaccgc tagaagaaac
    75781 cagccgattg ttcctatgaa atactttaat ttttcgaaca ttgtatcacc tcgttgtcag
    75841 tatatcacgg atcagtaaat tgggggtgtt aagaatctcc taaaatagac aaaatttgtt
    75901 ctattttcct aaagcaaata cttgtaagat acagtaagtg ataccagaag caatgaccgg
    75961 tccggcggcg attcctctta agaagacaac acctaaaatc gtgccgaaaa caagtgcaac
    76021 agtgatttgt ggatcagaag caatcaatcc tacacccttg gaagataaga cagccactag
    76081 cccaccgcaa aaaacagcta cccagccaat aggggattta aaggcttcta atagatcacg
    76141 tagaccgatt tctcctgttg cgatagggat tagaatagcc gctgtgatga tcgtcacccc
    76201 aatattgatt cctttgcctt gaagccaagg gaaaaaggaa cgggaggctg gtatgagctt
    76261 cataatcaaa acaaaagctg ccgctatcat cagactttga tttttagcta aaattgctac
    76321 aagtaaaata attcctaaaa aaagccaact ttccatgaaa tatattcctc actttcttcg
    76381 aaacaatcat aacatgtttt tagaaagtta caaaagtagg aattcatcct tcaagaccta
    76441 ttcataagct gtttttttca taaaataaac aaaatcataa aaaaacactt tgcttatttg
    76501 acagaagaca gccgcgcttt gtatagtgga caagacttac atttttttga agaatcagaa
    76561 agatcaggta aaggtcttag taaacgcaag ccattcagaa taaccaatat tgtgcttcct
    76621 tcgtgtccta caactccaag aggtagattt aaaaattgca ggaagttaga agcaatcaac
    76681 aagagaataa caagaatcga aaaaataata ttttgtttga tgatccgccg catttttaaa
    76741 gatagccgat gactgtagac aaatttattt aagtcgcttt tcattaagac gatgtctgcg
    76801 atatccatag cggcatctgt cccttgcccc atagcgacac ctaaagaagc ggctgctaaa
    76861 gcaggcgcat cattgactcc atcaccaacc atcgcattta cttggtaaag ttcattctct
    76921 tttttgacta gttgtgtttt ttcttccgga gtacagcttg catagtaatg ttcaatccct
    76981 acttgttcag caatggcctt tgctgtgcca gaatggtcgc cggttatcat acttgtatgg
    77041 atgttttggg atttaaagta ggaaattact tgttgggtat ttgcttttgg aatatctagc
    77101 agacctaaaa cagcaattaa ctgctgatct ttagaaagat aaatcacggt tttgccttga
    77161 ttttccaaac gttcgatcat ttccgcaatc tctttgctga ttatcatcgt ctcaggatca
    77221 tatgcgtgct tgccaacttt ccattgcgca cctaaatagg tagtttgtaa tccaaaacca
    77281 gtaatttctt ctattggtaa gtattggatt tcttcaggta ttgtgcaatc gaaatattgc
    77341 aaaatcgcat gagcaagtgg atgcgtcgtt ttttgttcca tagcaacaag aagttgttgt
    77401 gccaaatcct tttcatcaaa gaaaaagctg tcagttacaa ctggttttcc tttagtgagc
    77461 gttcctgttt tatcaaaggc aatcgctttt aattcagaaa gcttttctaa atggataccg
    77521 cctttgatta aaatcccatt ttttgcagaa tttgaaagag cagctagaga agctggtgta
    77581 gcagatgcga caagcgcaca aggagaagcc acaactaata ataccattcc tcgataaaag
    77641 ctttcatccc aactccaacc taggaaaaag tgggggagaa ggatcattag aggaacagca
    77701 agcaaaatca attttacata attattttcg attcgttcga taaatgaagc tgtttgagtt
    77761 ggcgtattct gcgcttcttc tactaattgg ataatcttag caaagacagt ttcggaactc
    77821 gtttttgtta ctcgaatcgt gatgggattt ccttgattca gcgttcctgc atacatctca
    77881 tcgcctaaat atttttctac aggcacagat tcaccgctta atgcagactc atcgatcgtt
    77941 gcctgtgtgc tttctaaaaa gccatctatc ggaacagctg ctcctttagc gacaaatacc
    78001 aagttatcca cctttagttg agaaacatct acttcttgca tttgtccatt ttcttttaat
    78061 aattgggctt tttgtggttg aagattcatc aaagcagtaa tttctttttg acttttatta
    78121 gttgtgtatt cctctaatgc accgcttaaa caaaagatga atgtcaacat tgctccttca
    78181 aagtaattac cgatcaaaca ggcaccaata gcagctaaag ccatcaataa atccacattc
    78241 agtgtccgat cattccacaa ttctttcaag ccttccgatg tttgtttata tccaccgatg
    78301 ataatggcac tgatataaaa aagtggggtg atggtaagag agaatcggtc gaagataaaa
    78361 ccgaagatca taaataaaag gcagccgatt gttgctgcaa aagctttttt ctgattagtc
    78421 atcgttatta gacctccttg tcaaaacaag gatagcataa taaaaatgta attgataata
    78481 ataacagcta aatgagaacg ataatggtta tcatttggtg attaagcttg atgttgtttt
    78541 tattatttat aatgattatt attaaagaaa ataaaaaacc agaacatttc tcaaataaga
    78601 gaagtgttct ggttttttct acattgcaat aaaccaataa ccaatcaaaa tgataccaag
    78661 gataatacga taccagccaa aagcggtaaa gtcgtttttc ttcaaatagc ttagtaagaa
    78721 tttgatagct aagacggaaa ccacaaaaga tacgaatgtt cctacaagaa gaacaacagt
    78781 ttcttccatt ttgaatgaat tcccttcagc taaatatttg acgatcttca agccgcttgc
    78841 gccaaacatg acaggaatcc ctaagaaaaa tgaaaactct gtagcgacaa aacgcgaagc
    78901 accaatcaag atagatccta ggatcgttgc gccagaacgg gatgttccgg gaacaagtgc
    78961 caagacttgg aataacccaa caagaagagc tgcttggtac gtaaagtcat tcagagaagt
    79021 ccaacgaggt gttttgtttt tgttgcgttt ttcgacaata ataaaggcaa taccgtaaac
    79081 gatcaaaaca atggcaactg gtaagaactt gtggaaattt gcttctaacc aatcatccaa
    79141 aggcaaacca atgatgatgg ctggtatgca agcaacgatc actttaaacc aaagtgtcca
    79201 cgtatctttt ttttctaccg ttgatttact tggagaaaat gggtttaact tgtgaaaata
    79261 aagaacgacg acagccaaga tcgcccctaa ttggataacg acattgaaca tcgacataaa
    79321 ttgtgaactg gcatccagtt tgatgaattc atctgctagg atcaaatgac cagtactact
    79381 gatgggcagc cattccgtta ttccttcaat aataccgaga atcactgctt tgataatatt
    79441 tgcaaaaaac ataaattcct tccttcccaa ttaagataca tcttatagta taccgttatt
    79501 ttttgagaaa cccaatctgt tttttaatat taagaaaaac ttgagaaata aagcagataa
    79561 gtacacgaag agaaaaaaga agacaaagcc ctcgttcaga ctttgccttt tatgattctc
    79621 tggtaaaaat taaaatatcc ccattataga aacgagtcgc gactatgtgt tttcccgtta
    79681 tcgatataag acgtatcatt gatgccgtgg atagaaaatc gaccgtttgc ataagtgacc
    79741 tttgttacgc tgccatttaa aagcccagca cgaacaggct gtttaggatc gatcagatta
    79801 agcaaaaagg cgatcgtcaa accatgagat acgactaaaa catttccacc accatttttt
    79861 tcgcagtgat gggcgatatc ttcaaatcct gtccatacac ggtctcgcaa tgtttcataa
    79921 gtttccgccc acccagcggt atctaagttg tatacagcat tagcaatttg ttcaaaagaa
    79981 acttctgtgg taaacatttc atcatatgtt ttaaaattca atacacgagg gatcacaccc
    80041 cacatttcca tgtcatatcc accttcaaga gacccgaaac accattctct aatccttttt
    80101 tcaataaaat aaggaatttc ttttccctta gaatgttctc ctagaataat acgggcagtt
    80161 tcgattgcac gaccactgtc actagaataa gcaaatgaaa agtcgacatt ttttaacccg
    80221 cgacctaaat aatgaatgcc ttcttgtcct tgctttgtga ggggtgtatc acaccagcct
    80281 tgtactcgtt caattgtatt gaacatcgtt tttccgtgtc gtacgatata aagtgtagtt
    80341 tctgtcattt tattctcctc ctaagtcgtt ttaacgattg aaaaaaggat ttgtcctttt
    80401 ttcctgttca atcgtcgttg catcgccatg tcctggatag actgcaaatt catcaggtaa
    80461 tacaaacagc tgggtccgaa tactatgaag taattgttct aaattccctg tatacagatc
    80521 ggttctaccg atacttcctc taaacagggc gtcgccagaa acgacaaaat catcaaaaat
    80581 aaagctgacg cttcctatag aatgccctgg ggtagggacg acgcgaaaag acatgtttcc
    80641 taaagtataa gttttcattt caaattcata ttctgcaggc gagacaataa catcagcaat
    80701 atcatcatgt ctaccgagtc cagaaagatt caaaatcgga tcacctagcc atttttgctc
    80761 tagtgggctg acataaactg ggatttgata atacgcgcgt aaaggttcca ctgcaccgat
    80821 atgatcgtag tgagtatggg taagcaaaat cgctaccggc tgttggtttg tttttttgat
    80881 ttcttgtttg attcgttccg catcttctcc agggtcaatg atcaaaagtg cttcttcgtt
    80941 gtagaccaaa taacagtttt cttcaatcat tcctgttttt aatctttcga tatgcatgtg
    81001 cattcctcct tgatagccaa aacttctttc atccattagt ataacgcatt cattgctagg
    81061 aaacaaaaac aggtacttat ttctctttac ttatctgaat tatcagacta tatgaaaagt
    81121 atttggatat tctaaagaga aggaaagtaa gttttcatag cattttaata tgtccttgtt
    81181 acattagatt catccaaaaa tccaaattct atatcctata tccctgccta atcagcaggg
    81241 tgttttttta tgtttggaaa gagagctctt tttgctaaac taggtttttt caggtaatct
    81301 tagagagaaa gaggtggtgg aaatgatcaa acagtcaaaa atatctgtgc ggcacttagt
    81361 agaatttatt ttgcgacgtg gaagtatcga caatcgtaaa aaaagtaacc atactgcatt
    81421 agaaggagcg agaatccacc gcaagctcca aaaagatgcg ggagaaaact atgaaaaaga
    81481 agtcttttta aaaacaacag ttcaattaga tgaatattac ctgatcgttg aaggccgtgc
    81541 agacggtatt ttcaaaagag acggtattta ttatatagat gaaatcaaaa cctccgaacc
    81601 acgatttgaa gatttagaac cagaacaagt ggaacttttc tttcatcaag caagggtgta
    81661 tgcctatatc tatagtcaag aacatgattt acaagaaata aatctgcaat tgacttactt
    81721 ccagacggca gaagaagtga tcacgagaaa ggttgaacat cagacaagag agcagttaga
    81781 aacttttttt aaaaagctga ctgaagatta taaagaatgg cttgtttttc aagaaaactg
    81841 gcgcactgta cgcaatgcct ctttgatggc tttgaaattc ccccatgatg agtataggaa
    81901 aggtcagcgt gaactagcgg tagctgctta taaaacgatc cgtacgaaac agaaattgtt
    81961 tgtagaagca cctaccggaa caggaaaaac aatctctacg ttattccccg ctttgaaagc
    82021 tgtaggggaa gaagagggag aaaagatctt ttatctaacg gctaaaacaa taactagaca
    82081 agtagctgaa gatgctatga cagcattaaa agatacagga gctgaagtaa aaagtgtcac
    82141 tttgacggcg aaagacaaga tctgcttttt agatgagacg acctgtaatc cagatcagtg
    82201 cccatatgcc aatggttatt acaatcggat taatgaaggt ttatgggatc ttttgaatca
    82261 tgagaatcag atcactcgtg aagtcatcga aacttatgca agaaagcata cactttgtcc
    82321 tttcgaacta tcattagatg tcagtatctg gtgtgacgta atcattgggg attacaatta
    82381 tttatttgat ccaactgttt atttaagacg tttttttgaa gatgaaaaaa acgaggacta
    82441 tctgtttttg attgacgaag cacataattt ggtgaatcgt tcccgagaga tgtattcggc
    82501 agaactatct tatgaaaaaa cgaaacgaag taaggaagct ataccaaagg aattcaaaaa
    82561 acttcatcgc cgtttcaaca aactattaaa agaatttgat tcgatccgag aaatagcaaa
    82621 agaagatcat tgggattatc atcatcaaaa agcaccggct gaatctttag taaaggcagg
    82681 ttatcaatta agcgaaaaaa ttaaagaatg gctggcagaa tttcctgagc acccatcaca
    82741 agaacaattg cttccttatt attttgattt gcttcatttt ttgaaggtca gtgaatttta
    82801 tgatgatcac tacgaaacaa cagtcgaaaa aacgtatcgc gatctgatag taaaagagtt
    82861 ttgtattgat ccaagcttgt ttcttgagca gtcgttggat aaaggaaaaa gcagtattct
    82921 tttttctgct agtttttcac cactctctta ttatcaggaa acactggggg gacaaaaaag
    82981 tctggcttac aaactgccga gtcctttccc agaaggaaac cagcaagttt tcatcgcaaa
    83041 ttacctagag acgacttatc gaaaaaggga acacagtctg gcaaaattag tagagacgat
    83101 tcatgctttt gctgatggaa aggtcgggaa ttatttcgtt ttctttcctt cttatcaata
    83161 tttagatctt gcggtggaag cattcagaca gcaatatccc gacagcaatg tgctaatcca
    83221 agaaacggac atgaatgagg aagaacgcga acgattttta acaaaatttc aaacaaatcc
    83281 cgctgaaaca ttgattggat tttgcgtact tggcgggatt ttttcagaag gaatcgattt
    83341 gagaggggac cgattgatcg gcagtatgat cgtaggtgta ggtttgccgc agatgaatca
    83401 tgagcaggaa ctgatcaaat catattatga tgagaaggaa caccttggat ttgcttacgc
    83461 ttatcagctt cctggaatga acaaagtctt gcaagctggt ggtcgagtga ttcgtggcat
    83521 ggcggatcaa ggaatcgttg tattggcaga tcaacgattt tctagttttt cttatcgacg
    83581 tttattccca caacattggc aaacagcaag agaagtacga agtgttgggg aattggaaga
    83641 aggaatacag cgtttttggt tatcaaaaga agcagtaaat caaaaaaacg aggaatgaca
    83701 gacgtcagcc tcgttttttg attaacgata gttagtgaat tgcaactcga ttggtaagtc
    83761 aagtttacgt aataaagcaa tcacagcttg tagatcatca cggttcttac ctgtcactct
    83821 aatctgatct tcttggattt gtgcttttac tttcagtttt tcatttttga tagctgtagt
    83881 gattttcttc gcgttttcac gatcgattcc gttgaccaaa tcggcagttt gtcgagcttt
    83941 gccacctaga gcgtgttctg attcggaaaa atggatattt ttgattggca catttctttt
    84001 gatcagctta ccaaataata catctttgat ctgttcgatt ttgaaatcat catcgctcaa
    84061 tacaactaga ttgctgttct ctaatttgat ttctactgta gaatccttga agtcaaagcg
    84121 attggacaat tcttttgttg tttgctgaat cgcatttttt acttcttctg tattgacttc
    84181 tgatacaatg tcgaagctag catcttttgc cataggaacc ctcctgatat acatataaat
    84241 atttaccata catctatctt atcataggat tagggcagat tcttacctgt ttgctaaaat
    84301 tcttctcatt tgagttcgaa gtattttatt ttaatagata aactgttatt cttacatttg
    84361 gaataccaaa gtaggggaga ggtgcttgtg agtaaaatta tgactgcgta tcataaaaat
    84421 gaaagattaa agaaaatagt ggttattttg ataaccggat tgaccgctgc ggtcgcttta
    84481 aattattttt tgattccagc caatgtcttt tctgcaggga tgaatgggat cgctcaaatc
    84541 atttcctcgc ttttatatga atggtttcat atcaagatag acacaggaac atttattttt
    84601 cttttgaata tccctgtgtt tgtattaggg tttctcaaag taggaaaacg agcaacgatc
    84661 cttagttttg tgaatgttgt atgtgtatcg gtgatgacga tgctgcttcc agtcggacag
    84721 atcactgata atattttgat gaatgcccta gtaggcggtg ttttattagg tcttggcgta
    84781 ggattatctt taaaaatggg ctttacaact ggtgggatgg atatcatctc tcttgtactt
    84841 tcacaaacaa ctggaaaaac agtcggaaac tacatgctga ttctaaatgg tatcattgta
    84901 gtcatcgcag gcttcttctt taactgggaa agtgccttgt atacgattat ttccatttat
    84961 gcaatgactc aagtaattga tgccatccac acgagtcatc aaaaagtaac agcaatgatc
    85021 gttaccgtca agccagaaga ggtaacagaa gaactagcaa aacggatggt acgtggaatg
    85081 acattactgc cgtctgtcgg tggctattca aaaaaacaag ggaacatgat catgatggtc
    85141 atcacccgct acgaaatgta tgatcttgat cagatcgttc atgaaatcga cgacgatgca
    85201 tttatcaata ttttaccaac tcattcagta tttggccggt ttgcaaatga aaacgaacaa
    85261 aaaatgtatc gaacaactgg cgtattgcca gaaataaaaa atcgttcaca aaaaaaatga
    85321 ggaatcaggt ttattttaga ataaatttaa tctattacat ctaataagaa catttttata
    85381 aatttaaacg agaatcttac ttctaaattc tcatttacaa gcagctaaaa aaagagtatg
    85441 ataaataaaa atcgtgttaa ggagtgtcgt acgatgagcg aagcaaacca agaacggtct
    85501 ggacaagaaa tagaactaat caaagaacgt attcttgctg ccttggaaat ggtgattgat
    85561 cctgaattag gaatcgacat cgtcaattta ggcttgattt atgatataga attcaatcct
    85621 gaaaatggag aaacagtcat taagatgact ctaacaacta tgggctgtcc attagcagat
    85681 attttaacag aatctatcca tgacgcatta aaagaagtgc cagaagtaac gaaagcagaa
    85741 gtcaaactag tctggtatcc agcatggacg acagataaga tgagccgtta tgcacggatt
    85801 gcgttgggga tacgatagaa atcttggctg actagctatg agaagcaaat aggaaaaaca
    85861 aaaaagcctt ttatcctttc tagaagaaaa gagataaaag gtttctttgt ttataaaatt
    85921 ttgtctgcta tattataagt taattaaata aatgtgttct attgataaag gacattcaaa
    85981 tccctttcct tttggaatcc ttctttttta catcagtttg attttcgtat agtattcttt
    86041 ctcatcttca cgataaatcg cagccccatt tttttgttgt gctttaagac tgccaagatt
    86101 ttttttattt acagacaaaa gtgcctcatc aatgccgatt ttttttgcct cttgtagtac
    86161 taatgctaat ccttgtgtgg catatccttt tttacgataa ttaggggaga tgccgtaacc
    86221 aatatggcca gcgccgtttc ttaatgtttc gttcagttta tggcgcaaat taaaaattcc
    86281 tacatactca tgttcatcac tttctaaaat aaagacggtt gcgggaacgt aactctcagg
    86341 aagatcgatt cctaaagacg ttttttcgca tttttttaca taatctaaaa attcagcaaa
    86401 tgtatagcca taagcattgt tgataaatcc actctcattt ggtccaaagc tagtttgtag
    86461 ctgataagct ttctttaaat ctgcttccca tagtttgatc agtttcatcg tattcacctc
    86521 tttaagtaac cttattcatt tgttttctac tatagcacta ttgttgtaaa tagccatgcc
    86581 tatttttatt tattgtgtca tatcgtatta agaatcatcg aacaatacaa atatgaatta
    86641 caataaaaaa attatttgaa gttcgttcat tcgttactta tgatctctag aagaaagaaa
    86701 acgtgaatta cttcagcgtc tagaattcca gaaggatagt aatcaacaga agaaataatc
    86761 aatatccaaa tgaaagaaga tagctgaatc gagaaaaaga ggaaaaaaga aatgaagaaa
    86821 aaaataaaat agttactaat cccagagtcg ttcgtttaac attgaaatcg atcatatgga
    86881 taaaacagat tttttcacca accctcaata gatgatggag ttgctcggat gaattatttg
    86941 tgtagatggc ataagggagg gcgtacagaa atgaaaaaga acaaaaatat gttcttgaca
    87001 aaaaacacat gtaatcctaa actaaaagat gtgatgcggc tatggcggaa ttggcagacg
    87061 cgctagcttc aggcgctagt gagggtgacc tcgtggaagt tcgagtcttc ttagccgcat
    87121 aatttgtttt tttataaaga gaaggtacac ctggagcgat gagaaagaaa ataacatatt
    87181 atctaaaaga atataggaaa aattttaaac aacggaacca gattcaaata aatcaaaaaa
    87241 aatttgtgtg aaggtgggac agtttaaaac ctaatagatt gattcaaata gtagatttat
    87301 agattctgat acaagaaata ctggcaaacg atagttaagg aataaagact aaacttaaac
    87361 tcaaaaagag gtcatgcgaa agaataaatc gcatgacctc ttactatatt ttgaatgtgt
    87421 ttaaacgttc aaataatgaa tcttagtacc aaccgtttgc ttcccagaat gctttcgccg
    87481 cttcccaaga accataacgt gaagtaacat attgttctgc tactctttct tggtttgcag
    87541 cagagtagtc accatttaag taagaagaat ctaattggta acggccgatg taacgtccgt
    87601 tcgttgctgt gtaagaaccg cttgattctt tttgtgcgat ccattctttt gcagagcttg
    87661 tacttgctgg agtagcagca gtttctgtta cagcaggagc aggttgtgtt tcagcaacag
    87721 gcgctgcttg tgtttccgtt tgaaccgttt cttgtacaac aggttgttca gcttgaacag
    87781 gttcagcttg gactggtgct tcttgaacgg ctgcttgagg ttcagcagct gcttgtgcag
    87841 agccttctgt tgggattgtt aattgttgtc ctgagtagat caggttaata tcagaaattg
    87901 aatttgattc tgcaatggca ttgatcaagg agttatcacc aacgtatttt tgagaaatcg
    87961 ttgatagagt atcacctgat tgaacggtat aagcttcgtc cgcatgagca gtcgttccca
    88021 tgaagaatgc agcgccggca gccaaagttg ttccaaaaag taaagtttta agtgatgtca
    88081 tgaaaaatct cctttattcg ttaaaaagtt ttatttgttg tgttcaacga ggaatacttt
    88141 aacacgtgaa aatatttcat aggtaaaaga agcatgacaa tttatgacaa atccacgttt
    88201 tttgtaacag aatgatgttc gctcgatgtg aaaaatgatg aggaatttca cataatgcag
    88261 aaataatggg attagaacag gtgttctgat gagaaaagaa atgtataaat aacttgaaag
    88321 aaattgcttt tgttcatcat tttatttaca tattgcgtat attttttgta tttttgcttg
    88381 agatgttaca ataaaagaaa aaggaggcgg ttccaatgag taaaagatac cagaacatca
    88441 tggtagcagt tgacggatca agacaatcga tcaaagcgtt cgctgaagcc cttgacttag
    88501 caaaggacaa tgaagcccac ttatttatcg tgtcaatcat caacaaagtt gagctgaccc
    88561 atagtgccta tgccttttca aaaatctatg cagatgaaaa acaaagaaca gaagtagcca
    88621 tgctgaaaaa aatcaatgat gccaaagagt acggcattgc tgagatccac gcaatagttg
    88681 aaactggaga tccaagaaat ttgattgcca atgtcatccc tggacaagaa aatattgatt
    88741 tgatcgttat gggagcgaca ggaaaaggtg ctatacaaca agcattagtt ggatcgaccg
    88801 cttcttatgt cgtatcacat gccccttgca gtgtgttggt cgtgaagtaa tgagataagg
    88861 gaggaataga aaatggttcg tcctcaagaa gtccgtgcgc caaaagaaaa aatagaaatt
    88921 ttagcaatta ttgaagacgg cacacaaaca aagaagggat actcgatcgc tttagtaaag
    88981 tggaaaggaa aaaaaggtgt tgctctgaga tgggatggag ataaccaaca agataaagga
    89041 ttccctgtca cagctaacgg ttatcatcca gcgtggtttg ttctgcctga taaatttatg
    89101 gaattataca gctatgatta tgcaagagcc gcagcatcaa tcaaagcatt agataaatta
    89161 acagaagagc agaatgaaat ggaggaaaaa taaaaaagac gaaccaatca gcctttagaa
    89221 aactgattag ttcgaggagt aaaaatgaaa aaaggttatt tgggatgaaa ctagaataat
    89281 gcgtataact taaataaaac ttaaagcaat aaaatggcaa gagggtgagg caaatggaag
    89341 caggaaaagt attacaggaa gtaaaagcac tatgtgcaga taaaaaatat gaagaagcga
    89401 aaagcctgat cgaaaagaac aaagaaaatt tggaagaaaa gtacccgatc gcacaagaat
    89461 ttatagaatt aaaacaagga acgatccttc accgattcaa acattttttt ggtataacag
    89521 aatagaaaaa acgattaaag atcggcagaa atttgctgca tctttaatcg ttttcttttt
    89581 aaacatgcga gggattcaat tctgattctt atataaaaaa tagatccaaa taataagaaa
    89641 aattactgaa agcgtcaatt cgatgatgtg tgttattaat acagacgttg tttcccaatg
    89701 cctaaaagaa aaaatttgat aagtaaaata tacagcaggt aaagaggcca gtaaaactga
    89761 aaacttcttt tttgtccatt ttatgtaata gaaaagaatg cttatcataa taaaaaaagg
    89821 aatataaaaa acaaattgac cgatcgcgat catactattg cctccgataa ataaagtcca
    89881 tgatacaaaa taacactttg tgcgaaatgg cgcaagcagt tttgtggatt tatccggtaa
    89941 aatctgtatc gattttgaaa ttagaggaga aacttgctat aatcaaagtg aaagaaggag
    90001 tgggattttc atggatcatg tagtgttaga aatcgatttg catttgatca ataatattcg
    90061 ggtgatttac tatgttgtaa gtaacagtgt cgaacaacgt gtactgacga ataaaataaa
    90121 tggtatttta gcaaagaaag acgttcaccg attcaataat ggtgaaggaa gttattatag
    90181 tatcccagta gaaaaaatta tttatacgac agtcaaagtc agagaagatc tagataccaa
    90241 aaaagcatat gaacctattt ttacaactta ttgattgaca gcagatggag gaaaaaaatg
    90301 aatccatatg aacaacttat tcaagatttg atcgatggaa aaatcgaaaa gattgatgta
    90361 aaaagagaag aattaatggc ttttcgagaa gcgtggctga agttggagaa tcgtaaatat
    90421 gtggtgggaa aagcctcact gaacggcaat gtgacttatc attacgatcc gacacgttta
    90481 ttttagtatg aagtattcag aaaagaacca aaggaggacg atgcagcagc attgtcctcc
    90541 tttgatttta caaaagtgaa agttttactt atttgaatag atttttaaat ttgtttttga
    90601 cactgtcgat atttacatct tttaaaagat tttgggcttt ctctttataa ggtcctaatt
    90661 gttctttatg ttcttcgata aatcgttttg cgccatcgaa attgccgttc ttaatcattt
    90721 ccttgacttt ttgaaataat tcttcttgat tcattttgaa cacatccttt gctatcaaca
    90781 tgatttttta catggacaaa acgagaaaaa ctgatttatc cacacgtcaa taatatcaaa
    90841 taacgatcat ttttactaaa aaaacactcg attctcgctt ctaaagtagg agaaaaatct
    90901 ccaacttggg acggatggaa tttctttaac tgacccatat actgaatata taacaaggag
    90961 gtagaaagat gaaagtgatt aaatatttga ttggactggc ggcgattagt ggtattttgc
    91021 tatttggact gaaatattat actgaaggaa gttatggaga aatccctggt atacttgatc
    91081 agctaaatcc attagttgaa aaaggagagg tctatgtaaa gacacaaaaa ccagaggaag
    91141 taaatgaata tggtacagca aggtatgtgc agaaagctgc tgatgccaat gggaaagaac
    91201 gaacggttga atttaatggt ctttctgtgt taaaagaaaa tcattatttg aaaattagca
    91261 ataaaggagc acacatagaa acgtatgagg aagttcctag agaaaaagtt ccggagaaag
    91321 cattagcaat tattgggtaa atcagttttt gtattaagaa tacgcccgat tttattattc
    91381 ataatttaat tatgtaaact aaatacaagt agtaaaaata atacaataat ccccctgcaa
    91441 aaagattgtt cttttacagg gggttcattt tttcagcaag cacatcaaat tgggatggca
    91501 gggttcgaac ctacaattgc ttgattcaga gtcaagtgcc ttaccagttt ggctacatcc
    91561 catttattca acaaaataat catagcactt tcctaaaaaa acgcaagtta tttttcttga
    91621 tcggatagtt gttgctttac tcgtaaaagg cggcgtacta gtttcttttc taatccagca
    91681 ggaagggcaa tcagttctgc tactgacaag acggtgtcca ataactgata ttctttgaca
    91741 ggttcattca taatatgata gatgtttgct aaacgttcaa tatattcaaa gcgagtatac
    91801 tctgttcgag caattagaaa tttcaataaa tcggtggctt tctcgtactc ttgatctgcg
    91861 taataaacaa gagattgacg atacaatttg atttccagtt cattgagggt agcaggtctg
    91921 cgacgctcgt tccactcatt aatagagact ttaccttgaa catttccctt gcagtcacgg
    91981 acaaaaataa tcggaatttc atttggatcc atttttttat gtgtgaattt ttccattatc
    92041 tacgctccct tcaaaggttt ggtatcttga gtataaggga tttttgtttg aattactagc
    92101 ttttctccaa agttagcatc tgtccaccca ttgcagtgaa aatcgccgaa aaatcgttga
    92161 tcggtactgc tcgatttttt acaccatagg gatcgttgac ataaatattt tctttgtcat
    92221 atccagtgac tacacaagca tgaacaagag gagtgactct tacttctcca ttatttgtgg
    92281 tccaagtcat aaaatcagtt tcatctggga cttcaaaatt gatagtcaca gaagtccaga
    92341 caggatttcc tttagatagt gcttttttga tatcatcgag ttgagcatcg gtttttggaa
    92401 aagtgtgata atccgtttgg acgatttgct gagcaaggga ggcaactggg ggaacataga
    92461 cgaccatagc ccagtctccg ccactgatat caccaacaaa tccttcatta ggatcgccat
    92521 gagtcccatc tgcattgaaa acagggacgt aatccaattg ctcagctaac tggtttttag
    92581 ttgtttcata accataaaaa gataaaagca tagaaagcga agtgacttca cagccatttt
    92641 ctaaagaagg agaatcaaac tggctctcta atggaacatc tagtaaaact tctgctttct
    92701 cttttgtctt tttcgttttt tgtgttgaac ttttttgtgc agtgttcatt gtatgttctg
    92761 gagaatggat atgtaggtaa taacttgtac cgcttaataa aagagcagct gtgcccccta
    92821 gaaacaatag ttttttgaac gtttttttct tcatttgaaa tctccctttt cagctgttta
    92881 tctttcctat tataaatgta tttttattgg aaatggaagt attatatttt aatatgtagg
    92941 aaataattag tttttaagga atatgtttta attttttgaa aaaaattctt ctaaatacaa
    93001 cagctgtttt aattgtgaaa acgaaaacag tacgctataa tgcctgtaag gttgattttt
    93061 aactgtaaat aaaaatcaat gagttaaatc tccaaagaaa tagcagtggt aatgtggaga
    93121 aaagttccag cagtttagga ggattttgat gacggaagaa atgattaatt taggagaaca
    93181 atatgcatgc aaaccaattg gttttacaaa aacggtcatt ggtgaagttg tatcaaaaat
    93241 gacaaactgc gccgtggtca aagttgccca atgtgctgca gaggaccaag aattattaga
    93301 tgaaaaagca agcatggttg ttgcaaaata tgatacattt gaataaagaa aacaattgga
    93361 cgtgcggcgt gctgcaagtc caatttcttt gagaaggtaa atcagtattc ttttcctatt
    93421 ttctggagaa gaaaaagcga ggcgagttgt catggtaaca ttctttacgg ttctattgtt
    93481 tttattcgtt gttgtgatgt ttttatttct ttggctggtt cgaaaagaaa ttatttatcg
    93541 gactgtgcga aatcgatggg tctacttggt gatacccttc ttagtgtcac tagtcatttg
    93601 gtatacactc atcagtcatc ctacagcaga tgaattggca aaagggatct tgtcagcaat
    93661 gatttttatt agttttttgt tggacagtag aggaatcaca gaagaaggac ttgttttgaa
    93721 tagctttgac aaaaaaggtg ttcctttttc tgagatcaat aaaattgtat tatatcagcc
    93781 aaaaggttct aaaatcgtaa aaatgaattt tttccgaaac ggatggcgag gaccgatgct
    93841 gaaattttct gcatcattag aagaattagt tccatttttg tcccaacgct taaacgatga
    93901 ggcagagatt gatattatga ttgatccaga ataaaaacag aggttgcgac aagatgtttg
    93961 tcacaacctc tgttttttat ttcaaataaa attatccaaa tacgcggaag cgatcggcat
    94021 cgttcatgta ttctttttcc tcagccggtg tttctggtga accgaatact aattgcgaac
    94081 gtagtttcca gtttgaaggg atattccatt cttttgcaac tgcttcgtca ataactgggt
    94141 tgtaatgttg caagtttgcg cccaatcctt tatcaactaa tgctacccaa gtattagctg
    94201 ttgcgattcc gtttgattgt tctgaccaat ctgggaagtt gtctgcatat aattcaaatt
    94261 gttcttgtag accttttacc acgtcagtat ctttgaagaa taatactgta ccataaccat
    94321 ttttgaaacc agctaatttg ttttgtgtat ttgggaaagc ttctgctgga gtcaatgggc
    94381 gaagtgcttc ttcagtgatt tcccaaagtt tttcatgtgc atctccgaaa aggataactg
    94441 cgcgtgttga ttgagcattg aaagcagttg ggctttcttt aattgcttct ttgatcaaag
    94501 ttgttaattc ttcattagaa agtgaaacat tacgtcctag atgatagatt gaacggcggt
    94561 ttttcaaagt gtcagtaaaa gttgtcataa taaaatttct cctttgattt gcgttttgca
    94621 tttttttaat tgattacgaa atgaagtata gcaccttaca aaaagtaagt aaacagatat
    94681 gctcacaaaa aataagcgaa gttcaaaaaa caattttaat aagaaaaatc gttatgtaag
    94741 gattttctta gttatcgctt tcattgttgt gttttaggaa tttttgctta tttgaaaaaa
    94801 acagctgata tataattatt aaatctctat cttctttttt ttatgatatt gccattaaaa
    94861 attacttgct tttatagaaa attagtttat atttcttaaa taagtttttt agttaaattt
    94921 ttcggtaaag atgtataata ttttctgaaa atttaaagaa ttggggtata gattatggaa
    94981 aaacagcaag acaagggctt cttcgggcag ccgaagggat tgtcaacttt gttcttcact
    95041 gagatgtggg aacgatttag ttattacggt atgcgtgcat tacttatcta ttatatgtac
    95101 gatacagttg ccaacggggg acttggatta ccacgagcaa cagcattagc tatcatgtcg
    95161 atctacggat ctttgatcta catgtctagt atcgtcggcg gatgggtatc tgaccgagtg
    95221 ttaggagcaa aacgcactgt attcttcggt ggagttttca ttatgcttgg ccacatcgtc
    95281 ttggctttac catttggtgt aagtacattg tttgtttcga tggcattgat tattatcgga
    95341 accgcctttt tgaaaccaaa tgtttctggc atggtcggac atctttattc aaagactgac
    95401 ttgcgaagag atgcaggatt ttcgattttt tacatgggtg tcaacttagg ggcattatta
    95461 gcaccactaa tcgttggtac aatcggtcaa gaatataact atcatttagg gttctcttta
    95521 gctgctattg ggatgttctt tggattatta caatacatca tccaaggacg caagacatta
    95581 gacggagtgg gtacaacacc gccgaatcct ttgacaactg aagaacgtaa aggattcatc
    95641 cgtaacttga tcatcgcact tgttgttatc gctgcagtat tcggcggggc acaactaact
    95701 ggtcatctga caattgactt ttttgtcaat acaatcagtg tattggggat tatcttaccg
    95761 ttgtattact ttatcaaaat gctgacttca aaagatgtaa ctgctgaaga aaaaccaaga
    95821 gtatgggctt atatcccatt attccttgca gcaatcattt tctggtcatt acaagaacaa
    95881 ggttcatcta tcttagcttt atttgctagt gaacgtacac aatctacgct atttggtgta
    95941 acgatccaag caagctggta tcaatcattg aatccaattt tcatctttat tctgacacca
    96001 gtattcgtaa cgatgtggac gaaacttggt gaacgtcaac catctacagt agtgaaattc
    96061 tctcttggac ttttatttgc aggattatcg tacttgctat tgatgttgcc gggtatgctt
    96121 tatggtacaa gtggaaaagt aagtccattg tggttgttgg gaagtttctt catcgtggtt
    96181 attgctgaat tgtgtctttc accagttggt ttgtctgtga caacaaaatt agcaccacga
    96241 gcatttgaat cacaaacaat cgctatttgg ttcttagctg atgcttcttc acaagcaatc
    96301 aatgcacaaa ttgcacgctt ctacacaccg ggaacagaat ctgcttactt cggtattatc
    96361 ggtgcagtag caatcgtcgg tggtatcttg ctatttactg tgaaagaacc aatcaaaaaa
    96421 ctaatgggct ctattcatta atcaatgaac ataaaaacag gaattgctta tttgcagcag
    96481 ttcctgtttt tt
//
LOCUS       DAFENC010000007        92128 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.007, whole genome shotgun sequence.
ACCESSION   DAFENC010000007
VERSION     DAFENC010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 92128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 92128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..92128
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.007"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(228..1115)
                     /locus_tag="LP493_000652"
     CDS             complement(228..1115)
                     /locus_tag="LP493_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL2132822.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(1112..1981)
                     /locus_tag="LP493_000653"
     CDS             complement(1112..1981)
                     /locus_tag="LP493_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2132823.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(2118..3404)
                     /locus_tag="LP493_000654"
     CDS             complement(2118..3404)
                     /locus_tag="LP493_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL2132824.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            3677..4255
                     /locus_tag="LP493_000655"
     CDS             3677..4255
                     /locus_tag="LP493_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBL2132825.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            4255..5184
                     /locus_tag="LP493_000656"
     CDS             4255..5184
                     /locus_tag="LP493_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2132826.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            5181..6917
                     /locus_tag="LP493_000657"
     CDS             5181..6917
                     /locus_tag="LP493_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBL2132827.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(6980..7816)
                     /gene="pheA"
                     /locus_tag="LP493_000658"
     CDS             complement(6980..7816)
                     /gene="pheA"
                     /locus_tag="LP493_000658"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HBL2132828.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(7813..8322)
                     /locus_tag="LP493_000659"
     CDS             complement(7813..8322)
                     /locus_tag="LP493_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HBL2132829.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(8315..9610)
                     /gene="aroA"
                     /locus_tag="LP493_000660"
     CDS             complement(8315..9610)
                     /gene="aroA"
                     /locus_tag="LP493_000660"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBL2132830.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(9623..10714)
                     /locus_tag="LP493_000661"
     CDS             complement(9623..10714)
                     /locus_tag="LP493_000661"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HBL2132831.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(10731..11897)
                     /gene="aroC"
                     /locus_tag="LP493_000662"
     CDS             complement(10731..11897)
                     /gene="aroC"
                     /locus_tag="LP493_000662"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HBL2132832.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(11899..12963)
                     /gene="aroB"
                     /locus_tag="LP493_000663"
     CDS             complement(11899..12963)
                     /gene="aroB"
                     /locus_tag="LP493_000663"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HBL2132833.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(12996..14018)
                     /gene="aroF"
                     /locus_tag="LP493_000664"
     CDS             complement(12996..14018)
                     /gene="aroF"
                     /locus_tag="LP493_000664"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBL2132834.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(14677..15651)
                     /locus_tag="LP493_000665"
     CDS             complement(14677..15651)
                     /locus_tag="LP493_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HBL2132835.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(15632..17515)
                     /locus_tag="LP493_000666"
     CDS             complement(15632..17515)
                     /locus_tag="LP493_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HBL2132836.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(17533..19758)
                     /locus_tag="LP493_000667"
     CDS             complement(17533..19758)
                     /locus_tag="LP493_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBL2132837.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            19873..20907
                     /locus_tag="LP493_000668"
     CDS             19873..20907
                     /locus_tag="LP493_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2132838.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(20974..21987)
                     /locus_tag="LP493_000669"
     CDS             complement(20974..21987)
                     /locus_tag="LP493_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL2132839.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(22065..22253)
                     /locus_tag="LP493_000670"
     CDS             complement(22065..22253)
                     /locus_tag="LP493_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HBL2132840.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(22677..22805)
                     /locus_tag="LP493_000671"
     CDS             complement(22677..22805)
                     /locus_tag="LP493_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBL2132841.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(22808..24181)
                     /gene="rlmD"
                     /locus_tag="LP493_000672"
     CDS             complement(22808..24181)
                     /gene="rlmD"
                     /locus_tag="LP493_000672"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBL2132842.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(24292..25347)
                     /locus_tag="LP493_000673"
     CDS             complement(24292..25347)
                     /locus_tag="LP493_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBL2132843.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(25357..26787)
                     /gene="gatB"
                     /locus_tag="LP493_000674"
     CDS             complement(25357..26787)
                     /gene="gatB"
                     /locus_tag="LP493_000674"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HBL2132844.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(26784..28256)
                     /gene="gatA"
                     /locus_tag="LP493_000675"
     CDS             complement(26784..28256)
                     /gene="gatA"
                     /locus_tag="LP493_000675"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HBL2132845.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKATFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(28256..28561)
                     /gene="gatC"
                     /locus_tag="LP493_000676"
     CDS             complement(28256..28561)
                     /gene="gatC"
                     /locus_tag="LP493_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HBL2132846.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(28667..30703)
                     /gene="ligA"
                     /locus_tag="LP493_000677"
     CDS             complement(28667..30703)
                     /gene="ligA"
                     /locus_tag="LP493_000677"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HBL2132847.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTVKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(30720..32954)
                     /gene="pcrA"
                     /locus_tag="LP493_000678"
     CDS             complement(30720..32954)
                     /gene="pcrA"
                     /locus_tag="LP493_000678"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HBL2132848.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLANPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            33109..34668
                     /locus_tag="LP493_000679"
     CDS             33109..34668
                     /locus_tag="LP493_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HBL2132849.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQKVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(34779..36710)
                     /locus_tag="LP493_000680"
     CDS             complement(34779..36710)
                     /locus_tag="LP493_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL2132850.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAAAEA"
     gene            complement(36728..37642)
                     /gene="pfkB"
                     /locus_tag="LP493_000681"
     CDS             complement(36728..37642)
                     /gene="pfkB"
                     /locus_tag="LP493_000681"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBL2132851.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(37639..38391)
                     /locus_tag="LP493_000682"
     CDS             complement(37639..38391)
                     /locus_tag="LP493_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL2132852.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLFNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(38550..38759)
                     /locus_tag="LP493_000683"
     CDS             complement(38550..38759)
                     /locus_tag="LP493_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132853.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(38770..40098)
                     /locus_tag="LP493_000684"
     CDS             complement(38770..40098)
                     /locus_tag="LP493_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132854.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     NQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            40234..40389
                     /locus_tag="LP493_000685"
     CDS             40234..40389
                     /locus_tag="LP493_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132855.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(40463..41050)
                     /locus_tag="LP493_000686"
     CDS             complement(40463..41050)
                     /locus_tag="LP493_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HBL2132856.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(41133..42383)
                     /gene="clpX"
                     /locus_tag="LP493_000687"
     CDS             complement(41133..42383)
                     /gene="clpX"
                     /locus_tag="LP493_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HBL2132857.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVERAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(42630..43919)
                     /locus_tag="LP493_000688"
     CDS             complement(42630..43919)
                     /locus_tag="LP493_000688"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HBL2132858.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(44073..45005)
                     /locus_tag="LP493_000689"
     CDS             complement(44073..45005)
                     /locus_tag="LP493_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132859.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLNEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(45162..45821)
                     /locus_tag="LP493_000690"
     CDS             complement(45162..45821)
                     /locus_tag="LP493_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBL2132860.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSIYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAIFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(45824..46849)
                     /gene="sppA"
                     /locus_tag="LP493_000691"
     CDS             complement(45824..46849)
                     /gene="sppA"
                     /locus_tag="LP493_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HBL2132861.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELASNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAMR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(46862..47152)
                     /locus_tag="LP493_000692"
     CDS             complement(46862..47152)
                     /locus_tag="LP493_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132862.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAEAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            47562..49367
                     /gene="glmS"
                     /locus_tag="LP493_000693"
     CDS             47562..49367
                     /gene="glmS"
                     /locus_tag="LP493_000693"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HBL2132863.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDSSDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(49439..50794)
                     /locus_tag="LP493_000694"
     CDS             complement(49439..50794)
                     /locus_tag="LP493_000694"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HBL2132864.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(50818..51987)
                     /locus_tag="LP493_000695"
     CDS             complement(50818..51987)
                     /locus_tag="LP493_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132865.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(51984..52871)
                     /locus_tag="LP493_000696"
     CDS             complement(51984..52871)
                     /locus_tag="LP493_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HBL2132866.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(53060..56740)
                     /gene="nifJ"
                     /locus_tag="LP493_000697"
     CDS             complement(53060..56740)
                     /gene="nifJ"
                     /locus_tag="LP493_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HBL2132867.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIVPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPAMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLENANPN
                     LAKALFEKTIQDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARAERRKKMEQATKEKKEK"
     gene            56938..57459
                     /locus_tag="LP493_000698"
     CDS             56938..57459
                     /locus_tag="LP493_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBL2132868.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLSCPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(58158..58723)
                     /locus_tag="LP493_000699"
                     /pseudo
     CDS             complement(58158..58723)
                     /locus_tag="LP493_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(58902..59558)
                     /locus_tag="LP493_000700"
     CDS             complement(58902..59558)
                     /locus_tag="LP493_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132869.1"
                     /translation="MRFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLRAGLITFIS
                     IVGFFLFTVIVFIWRTPAPPLPEITYGEFPFRLEYELNEELHVIEDTLIVEFDGFGMN
                     EGIGRYRRWTSRLASGEDLVLLLEVSDNKQIFYFPGPANYYMGDRLNGYNHTFPSASF
                     IERERGITRRDILHDKELLEQFGPLDQNTINEEELLNQYNIRLVNWEISEPIVNNFGD
                     "
     gene            complement(60126..61061)
                     /gene="whiA"
                     /locus_tag="LP493_000701"
     CDS             complement(60126..61061)
                     /gene="whiA"
                     /locus_tag="LP493_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HBL2132870.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(61095..62093)
                     /locus_tag="LP493_000702"
     CDS             complement(61095..62093)
                     /locus_tag="LP493_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HBL2132871.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAIDR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(62090..62974)
                     /gene="rapZ"
                     /locus_tag="LP493_000703"
     CDS             complement(62090..62974)
                     /gene="rapZ"
                     /locus_tag="LP493_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HBL2132872.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(63109..63840)
                     /locus_tag="LP493_000704"
     CDS             complement(63109..63840)
                     /locus_tag="LP493_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HBL2132873.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLQPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTVLQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSKALDTASEK"
     gene            complement(63844..65109)
                     /locus_tag="LP493_000705"
     CDS             complement(63844..65109)
                     /locus_tag="LP493_000705"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HBL2132874.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(65372..68188)
                     /gene="uvrA"
                     /locus_tag="LP493_000706"
     CDS             complement(65372..68188)
                     /gene="uvrA"
                     /locus_tag="LP493_000706"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBL2132875.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(68198..70192)
                     /gene="uvrB"
                     /locus_tag="LP493_000707"
     CDS             complement(68198..70192)
                     /gene="uvrB"
                     /locus_tag="LP493_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HBL2132876.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQVRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKNAAKALDFETAANVRDMILELKASK"
     gene            70451..71953
                     /locus_tag="LP493_000708"
     CDS             70451..71953
                     /locus_tag="LP493_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HBL2132877.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            71955..72692
                     /locus_tag="LP493_000709"
     CDS             71955..72692
                     /locus_tag="LP493_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBL2132878.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(73060..74226)
                     /gene="dnaJ"
                     /locus_tag="LP493_000710"
     CDS             complement(73060..74226)
                     /gene="dnaJ"
                     /locus_tag="LP493_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HBL2132879.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(74377..76206)
                     /gene="dnaK"
                     /locus_tag="LP493_000711"
     CDS             complement(74377..76206)
                     /gene="dnaK"
                     /locus_tag="LP493_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HBL2132880.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            complement(76257..76820)
                     /gene="grpE"
                     /locus_tag="LP493_000712"
     CDS             complement(76257..76820)
                     /gene="grpE"
                     /locus_tag="LP493_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HBL2132881.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            complement(76914..77957)
                     /gene="hrcA"
                     /locus_tag="LP493_000713"
     CDS             complement(76914..77957)
                     /gene="hrcA"
                     /locus_tag="LP493_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HBL2132882.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            complement(78191..79357)
                     /locus_tag="LP493_000714"
     CDS             complement(78191..79357)
                     /locus_tag="LP493_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HBL2132883.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNAHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            complement(79373..79600)
                     /locus_tag="LP493_000715"
     CDS             complement(79373..79600)
                     /locus_tag="LP493_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HBL2132884.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            80084..80674
                     /locus_tag="LP493_000716"
     CDS             80084..80674
                     /locus_tag="LP493_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HBL2132885.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            80864..81577
                     /locus_tag="LP493_000717"
     CDS             80864..81577
                     /locus_tag="LP493_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132886.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(81692..82702)
                     /locus_tag="LP493_000718"
     CDS             complement(81692..82702)
                     /locus_tag="LP493_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HBL2132887.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(82739..83221)
                     /locus_tag="LP493_000719"
     CDS             complement(82739..83221)
                     /locus_tag="LP493_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HBL2132888.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            83371..83739
                     /locus_tag="LP493_000720"
     CDS             83371..83739
                     /locus_tag="LP493_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HBL2132889.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            84204..84656
                     /locus_tag="LP493_000721"
     CDS             84204..84656
                     /locus_tag="LP493_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2132890.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(84780..85631)
                     /locus_tag="LP493_000722"
     CDS             complement(84780..85631)
                     /locus_tag="LP493_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HBL2132891.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(85644..86429)
                     /locus_tag="LP493_000723"
     CDS             complement(85644..86429)
                     /locus_tag="LP493_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL2132892.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            complement(86781..87722)
                     /gene="ribF"
                     /locus_tag="LP493_000724"
     CDS             complement(86781..87722)
                     /gene="ribF"
                     /locus_tag="LP493_000724"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HBL2132893.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            complement(87726..88649)
                     /gene="truB"
                     /locus_tag="LP493_000725"
     CDS             complement(87726..88649)
                     /gene="truB"
                     /locus_tag="LP493_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HBL2132894.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            complement(89017..91379)
                     /locus_tag="LP493_000726"
                     /pseudo
     CDS             complement(89017..91379)
                     /locus_tag="LP493_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
     gene            91827..92000
                     /locus_tag="LP493_000727"
     CDS             91827..92000
                     /locus_tag="LP493_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2132895.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
BASE COUNT        25732 a        19819 c        16197 g        30380 t
ORIGIN      
        1 tgacaatcag gacagtcatc ggcaatatag cagcaatcac ttctttaaaa ttttttagca
       61 tgtatcctcc tcctttactc tttaagttta ccttaaaatg aaagagtttt cgagcacaaa
      121 cttaaaacgt tatcatttaa tttttctcaa cataaaataa cacacgtccc aaaagtatct
      181 ttttacttgg aaaaatgact ttgaaggaac gcgcttattg tgttttttta ttttacagag
      241 ccgatcattc cttgaacgaa ttgcttttgc aaaacaaaaa atacgatggc agttggtaaa
      301 gtagcgatga ctaatccagc catgatcatt ccatagtctg gtgtatagga agcacccata
      361 gcagataaaa caagcggaac cgtccgttta tcaggagatt gcaaagctac taagggccat
      421 aaataattgt tccagctact catgaatgtg atgattgcag ccgcggcata ggtattttta
      481 gccgtcggca tatacactct aaaaaaaata cttagttctt ttagaccgtc taatcgagcg
      541 gcttctacta gatcttttgg aaaagattta acattttgtc gaaagaagaa gatcaaaaaa
      601 gcagtgctaa cagatggcag gatgacaacc aagaaactgt tgattcccaa aaccgttccg
      661 ttcaattgtg aaaacattcg atataaaggg atcatcaatg ccgcaaaagg aaccatcatc
      721 gatagcagta gaatattgaa aattaggtct tttcgtttac tttgataaat ctcaaatcca
      781 tatcctgcca ttgacgaaat cagcaatgca aacacagtgg tcaccaaagc gatcatcgct
      841 gaattccaaa gggaacgagt aaaattcagc tcattggaaa acaaattttg aaaattgatg
      901 atcaagttac tgccaatctt tatttttccc gatgtgatat ccacgggtgt attcgtcatt
      961 cccaaaacca tccagacaaa agggaaaatg gaaataaatg ataggatgct taatgctgta
     1021 tactttaata ctgacccaat tgtcgaacga agttctaatg cttgtttttt gacgttgggg
     1081 cgttcgattg tttctttttc taccatattt ttcatcgact ttctcctcct actttcgttt
     1141 ggattatcga caatatcaca ataaaggaaa caataacaaa ggaaactgct gccgcatatc
     1201 caaaattagg cgtgaattta taactcaaat tatagatgta ttgagatagg gtggtcgttg
     1261 catttgctgg tcccccgcca gtaatatttt gtacttcatc aaaaagctgc aatgtcccga
     1321 tcgtcgaagt aatggaagta aacaaaatga ttggttttaa atttgggatc gtcactttga
     1381 taaactgctg ccatttagaa gcaccgtcaa tagatgctgc ttcataaatc tccgaatcaa
     1441 tattttgcat gcctgaaagg aaaaaaatca tattgtatcc agtccaacgc caagtgatcg
     1501 aaagaatgat cagaactctc gcccaaattg gatgagtcaa ccagccaatc ggtgtgtcaa
     1561 tcataccaat gcccaacaac aagttgttta caaggccaga ttgagaaaat agacttttca
     1621 tgatcagaga ataactgacc atcgaagtga tacatggaag aaagatagcg gttcgaaaca
     1681 accctttata tttcaacttt ttatcattta aaaggttgga aataaaaagt gctagaaaca
     1741 acatgatcgg tacttgtaca agtaaataca ggaatgtatt aaaaaaagct tttttaaaag
     1801 ttgcatctgt caacatccgc tgataattac ctaacccgtt aaatgtcata ttgacagggg
     1861 gaccactttg aaaagacgtg atcaaagcca aaaccatcgg aataaaaacc atgattgata
     1921 tcaaaatgac tggcaagatt aaaaaagcat gcccgttttt gaataaatct ttctgcttca
     1981 ttcttttccc tccaattcta tcattgatta tctacatgaa aagacaagaa agacaatatc
     2041 tgtaaggcag acgtgatctt ttttgtcttt tcgtttgtct gatgaaaaag cgaagaaatt
     2101 cactttttta ccaccgatca attagccaat tgtgcttcta cttgtttttg tgtatctgct
     2161 agtaccttgt ctgtctcttc tccattgatg attcgatgaa gagcttcagc tacgactgct
     2221 tcaattgcat aggtctcatg tccgtaattc acttctggta tttcagatgt ccatgttgaa
     2281 aaatcgtcaa agatcttttg accactgtaa aattcagaag cttcttgata agcttcttgt
     2341 tcattcgcgc taagcatcgt agatactagt ccgatttctt tcgcaagagt gcccatcagt
     2401 tcttcattcg aagcaaacgt tgcttctagg aaatctttcg ctgaatcttc tccagctact
     2461 cctttgatca cataccagcc agcgccgcca aggttagaag cttgcgcttt ttgcagattt
     2521 tctggaagtg caggtattgg tgcaatcttc cattttccag attggttttc tgctccttgg
     2581 atcgttgaag aataccaagc gccagttggg ctagaagcta ctgctcctga ttgtatcgca
     2641 gttactccag cattccagtc agaggtttgt tcgactagat cttctttcaa aagagtggca
     2701 aacaattcaa gaccatactt taaagatgca ttgtcttgga tcgtgactgt ctccccatct
     2761 tcagatgtat accattctcc tgcctgttgc ataatcatcc ttactcgacc aaggtcagaa
     2821 ggattgactt cagcgatttt ctttcccgtc ttttctttga catctcgcgc tacttgaata
     2881 tactcgtccc acttcagatt ctccatatcc tcttctgtat aacctgcttc tgccatcaga
     2941 tccgtacgat agaagtttgc tgttacgccc gaatcgaaag gaacaccgta tattttatct
     3001 cctactttgt ttaccgcaaa tttatacggt gcaaaatgat cttcctttac aatagcagac
     3061 aaattagcga atgcatctgg ataagaagtc aaatagcctt gtatcctata atcttcaatc
     3121 aagacgatat tgggcaatcc ttctgtattc ccgctcgcta aagcggtgtt cagtttctga
     3181 acgatatcat cctgagacat cgtaacaact tctatctctg tttcttcgtt ctcataaact
     3241 ttttttgctt cattcactgc tttgatattg aatgtctcat cccacgccca gacagtgact
     3301 ttttcttctt tgtctgctgt actactagca cttccgcatc ctgttaagaa acctgatgct
     3361 gccgctaaac aaacgactcc agcaattaac tttctgatgt tcatttttat ccgctccttt
     3421 tccatccatt agttgtttac gtttgctaca ttcatcatac caaaatttga aaacggtttc
     3481 tttattattc agatacttca aaaatttctc ctaaaataat aaaaaaatac aaatcaacta
     3541 tgacaaaagg aataatctta gcatctagac caaagatcga aatggtgagg tttctttaaa
     3601 ataaaaatat ccttgcattt tctcctagaa ataagtattt ttaaattaca agactattct
     3661 taaggcgggt aaaaaaatgc caatacgcgt aattcttatc gatgatgaac agacgatttt
     3721 agatggaatg aaacagttga tcaattggtc tgagcacggg tttcaattaa tagggacttt
     3781 ttccagtccg ctgaaagcgc ttgatttttc tttggtacat gcaatcgata tcgtggtcac
     3841 agatgtaatg atgcctgaat taaatggaat cgaattatcg cggctattaa aacagcaaca
     3901 acctgaaaca cagatcctta tcctctctag ctatgatgaa tttgatatgg ttaaagattc
     3961 ttttaaagaa ggcgtcgctg attatctttt aaagcctcga ttgagtcctg atttttttct
     4021 aaattcctta actgccgttt cacaaaaaat caaaaaaaag cccaacaaaa gcccaatcac
     4081 caatcgttat gagcagatct gcgagaatct ttcacagcag attgctggac aaactcgtcc
     4141 attgcttgac cctcttcttt ttgaacacac cttgtttttc tgttatatac cgaaaaacgg
     4201 ccattcagtt caaaacaagg ctctaaacaa aaacagtcga tcacccattc attgatggat
     4261 agcgacgatt cgtttactat ttatcctgtt tctacctttt cggaagaatc cggctatgta
     4321 atcaatactg attccaaaga tacacttagg aagtttgttc aaaagtttcg tcaagaagtt
     4381 tttccaggtg atttttttgt tgtttctgat tcttttgcaa tccaagatat caatgaaata
     4441 ttccaagaga tcagaaattg caccaaagga caacgtttct atcataaggg aaagaacctt
     4501 gcttatcagc atgaacttct tccgttatta accaaccacg agcagcaagc aagtagttat
     4561 ttaacaaaaa tcgttcataa agactacgct ttagctgtca aagaacttga gaatttcttc
     4621 acgacgatat tggaacagcc tattgatcca gcttatttga aacatgaggc aatcaatcgt
     4681 ttctatgcat tactcaacgc tttggctgac gagcatgttg ggaatgaaga actttctttg
     4741 ctcaagatcg cccttccttc tttattagcc gatgctgagt atttcgaaga tttttctatt
     4801 cttgtcaaag aaacacttga gaaactcacc cacttttctg caaatgcaaa aaaagacaat
     4861 ttcgatatct tgactttgat ctacgagttc gtccaggaaa attatgagaa agaaatcaat
     4921 ttacaacttt tatccgaaaa atatcatttt tcatatagct atctctcagc catctttact
     4981 gaaaaatttg gtatcaactt ttcaaaatat ctaaaaaaag tccgtatcag taaagccaag
     5041 ctctttttga cggaaacacg gcttactttg acggaaatct gtgagaaagt cggctatacc
     5101 gaactgggtt atttctccag agtttttaaa gaagagacag gaatgacacc ttctcaatac
     5161 cgtaaaggaa cttttgtaaa atgagaaaaa aaatcaaaga gcatgaactc tttgccaaac
     5221 ttctgttcat tttgttcatc ggtctttttc tgcaagccat cgtcatttct ttgtttattt
     5281 atcatcgatc aagggatgcc tatatccagc tgttcaatca atcgaatgat gtggtactaa
     5341 aaaagattca atctgaattt gaaagtttga atgatacaat cgagaataca ttagccgctt
     5401 ttgattctaa tccagctgtc aaaagctatt tttccaatga tccagcccaa catatggaac
     5461 agcttcagca actaagaaca atccaaaaaa tgaatgactc tctttcaaaa atccatccaa
     5521 tgatcgatta cgatgtattg atctttggag aaaatggaag aacttttgtc ggaaacgaca
     5581 tgctcactgc cgtatctgcc gattcttttt ttcaatctgc gattgctcag agagtgaatg
     5641 aacgtgctgc tgatacacaa atgctttttg cacaccacgg attgactctt cgcgataaga
     5701 aagcacccag cgtcttcttt gtcaaaaaac tgaaaaatac attgaatcac gtttacggat
     5761 atgctgtttt atcgatctca tccaagcaac tagcgaatct ttttcaatct gtagtaaatc
     5821 ctgagatatc gaagatctcc ttcatgaacg aagaacagac gatcatcgca tcaaatgaag
     5881 aaaatacaat tgggagccga tcaatgattt tcaaaaaact aacagtaggt gaaacaacga
     5941 tttcaaatgg acagcagttg acccgtcttc ctctgtaccg ccaggattgt acattactca
     6001 gtcaagtcga tcttcattct ttatctaacc aaatgggcgt gatttttccg attattttgt
     6061 ataatatcgt gacacttgct tttgctggct cattggtatt tatgtatttg gatcgacaca
     6121 caaaatcgat ctaccgcttg attgattcgc taaaacggct agaggaagat ggcttaaaag
     6181 ctactgttcc tgtacaagga agccatgaag tccaattgct agggaatacg atcaatcaat
     6241 tgctaagtaa tgctcagcat cattatgaac agacgatcca agacgaaaag aagaaacgtt
     6301 cgcttgaaat ccaaactatg caagcacaga tacagcccca ttttatttat aatacgctga
     6361 ctagcttgaa atttttgatt tggcagaaaa aaacagatga agcagttcaa ggaatcgaca
     6421 gtttcattac tttactaaga agtacgattg ggaaaaaaga agaagtgatt ccagtcaagg
     6481 aagaaatcaa aagcgtacaa agttacatcg atcttttgag tatgcgatat ggcgaaagaa
     6541 tctcggctaa aataatgatt cctgatgaac tgcagtcatt atctatgccg aatatgatcc
     6601 ttcaaccaat tatcgaaaac gcctatcttc atgcttttca caataaaacg caaggattca
     6661 tcacggtgta cggcaaaaca aaaaatcagc ttcttttatt cgaagtgatt gataacggcg
     6721 atggcttcga tactgaaaat accaaacaaa aaaatgatca tttttcagga atcggcatca
     6781 gccatgtaga tgagcggata cgcctaatgt atggcgatgc atatggctta acgatccaat
     6841 cagtgattgg gacaggaacg actgtaacga tttgtctacc gcttcttcct aaaaatcaat
     6901 cagaatatca aaaataaaga atagccaagc gctgattttt ttattttaag ttaaataaat
     6961 caatcagtat tcttgacttt catctacgcg tctcttctac tgtcagcact ggataacagc
     7021 ccaatatttg actttctcct ccgagcatct tgatttcttg gagcgcattc tctactaatg
     7081 tcattggacg gtccaacaac aaatcgatca cgaaaaaata ttctcccaag ctagttttca
     7141 atggtcggga ttcaatctta cttaagttga tttcccgcca gccaaaagct gccagcattt
     7201 tatgaagcat ccctggccga ttagcaggta gtgtcaagat gacactcatt tttactggag
     7261 ctgactgctg gctggtcatc tttcggtcac cgacgatcca aaaacgtgtc tggttcaact
     7321 cattatcttg gatattctca gctaagatct ccaatccaac atgctgtgct gtttctaatg
     7381 aagcaatcgc tgctgcgtct tctttcggat gttctgctac atacattgct gcagcagttg
     7441 ttgattctgt tgctactaaa ggaacattag gataatgcgt ttctaaaaac tgttgtgatt
     7501 gtgctagtgc ttgtggatgt gaaaggattt ttgtaatctt tgttgctgga ttgcctaaaa
     7561 gctgctgctt gataggaaga acgatttcac ttttaacttc gacttctgga tgtttggaaa
     7621 gaagatcgat tgtgtgatga acagctcctt ccaatgaatt ctctacagga acgacagcca
     7681 gatcgacttg tttgcgaaac aaagcgcgca aacaaacagg gatggaagca tacgcagtca
     7741 attgttctgt aggaaatagc tgacaagccg cctgataagt gaatgaactt tctggcccta
     7801 gatagctgac gttcatatgc ttttgatcct ttctataatg gtatcgatga tcttttctgg
     7861 tgtttgattg gtcgtgttga ttcgatgtgt cgcactttct tcataccaag aaagtcgttg
     7921 tgccaataat gcttttattt cttctcttgt ttttccaaga gctaaaggtc gaatagacgt
     7981 ttcatcttgt tggatacgat caactagaca gtccgcttct gcctctaagt aaagaacaat
     8041 cggctgtgtt tttaaaaaac gccgattttc tgcactttgg acaatccctc caccagtcgc
     8101 gataattttg tcttcatttg acagctttct taaaatatct gactccactt ttcgaaagct
     8161 tttttcaccg taatagtgaa aatattcggc aatcgacaat tggatatgtt cctcaatctt
     8221 tgtatctaaa tctacatact ctttttgtaa acattgagct aaccctttac cgattgttgt
     8281 ttttccagcg cccatgaaac caatcagcaa aatgctagcc atgagcttct cctcctgaca
     8341 caagttctgc taaatcgtca aaaaatgccg gataagagat tgaaacagct tcagctcctt
     8401 ctagttcgca aggtccatca gctatcaaag cagctacttg cagcatcata ccgattcgat
     8461 gatcgcctct gctggacact tttgcgccat gcagaggtgt cggcccatgg atgatcagac
     8521 cgtctgctgt cgcttttatc tttgctccca ttttctgtaa ttcttctgcc accgcatcaa
     8581 ttctgttggt ttcttttact tttaattctt ctgcgtcttt gatgatcgtg attccttctg
     8641 cttgagtagc cactaaagct agaatgggca attcatcaat cagacgcgga atgatttctc
     8701 caccaatcgt tgctttcttc aaatgactcg tcttgacact taaatcagcc gattggttct
     8761 gttcattgtg attcgtctgg gtaatcgctg cgcccatctc ctccaacaca tctaagatac
     8821 cagttcttgt tggattgacc ccgacatttt ttaacaacag ttggctttcc ggaacaagaa
     8881 gtcctgctgc tagaaagaaa gcagctgatg aaatatcacc tggaacagtt atctgttgac
     8941 cagttaattt ttgcggtccg gtcactatga tcgttttatc ttccactgtg atccttccgc
     9001 caaattgacg aatcatttct tccgtatggt tacgggaacg ttctttttca acgattacgg
     9061 atgtgccttc tgcttgtaat gccgcaaaca gcaaagcaga tttgacttgc gcactggcta
     9121 caggcatatt gtatcggata ggtgataaag agcgggttcc tgtcacagtg attggtagat
     9181 actggtcatt ttcttctcct tgcaagtcag cgcccatctc gcgtaaaggt tccatcactc
     9241 gccccattgg acgtttagac aacgaagcat ccccgaacag agtagtcgta aaaggctgtc
     9301 cagccaaaat acccatcaat aaacgtatgg tcgtaccgga gtttcccatg tcaattgatt
     9361 cggttggttg gacaaatgag tggctaccgc gaccatgaat cttgatcacc tcttcctctt
     9421 cttcgatctc gacacctaat tgttggaagg catgtaaagt actcagacaa tcttctgcgc
     9481 gcaaaaaatt ttgtatagtc gtcgttcctt cagcaattgc tccaaacatg atgctgcgat
     9541 gggaaattga tttatctgct ggtatcctaa cagtccctct taatccatgt atttgttgta
     9601 ataattgcat ttatccagcc tcctatttga tccagcaatg ataactggta ttagacataa
     9661 tgattctttt tgcttgtaac aaatcctgtt ggtttttaaa actgatttgc agtattccta
     9721 aaatatcttc cctggtctct tggatcttca aattaatcaa agaaactccc gcttttccga
     9781 tcagtccagt tacttctgca ataacgccag gttcatctgg cacatcgata aataaatcaa
     9841 aaaaggcagg aatcgcgcct tgcttatgga caggcaactg gtctcgactt tcttttgccc
     9901 gattgaaaaa agaaaagatt tccgattggt tctcagtcat gatccattct gctatttgtg
     9961 tcatttcttg ttgccaatct gccaatcgtt ccaataatat ctgcttattg ctcaacaaaa
    10021 tatctgtcca catgacagga tctgaggaag cgatcctagt gatatctcga aagcctcctg
    10081 ctgccagttg tttggctcgc ggatactctt gattgaattg ttctgcctga ttgactaagc
    10141 cagctgccag aatatgtgga aaatgactta gcattcctgt tatacggtca tgttctcttg
    10201 ctgtaagagt tacatatttt gctttggttc cgcaaaatag ttcttgcagt ttttcaacat
    10261 cttttttcgt cttttccaaa ggtgtaaaga tgtaataggc attttcaaat agtttagcat
    10321 ctgctgcctg tatacctgat ttatgagaac cagccattgg atgtccaccg acaaaccgaa
    10381 gatttttctg ctcagcggat gtcacgactt gctgcttcgt actgctgaca tccgtaatga
    10441 tgacgtgatc agacaagttg attctttcaa ggacatcaag ataagctaag gttgtacgga
    10501 cgggaacggc taataagata acgtctgctt gttctgcacc tgtttcaaaa tcacttgcaa
    10561 cgtaatcaac gatctgctgt tctactgctt gctcacgggt ttttgactga ctatcccaac
    10621 caactactat cagttctgga ttggtctgac gaatacaaag tgccatagaa gcaccaatca
    10681 gtccaagccc cacgataaaa acatgttgtg ccatcttatt tgcccccttt ttagtaatgt
    10741 ttcaagtagt cacggtactc cttcactgca gctttcaact caacaagcga atcacttggg
    10801 aattttgaca atagctctgt cgctaccaca gtggctacaa cattttccgc aacgacgcta
    10861 gctgcaggaa ctgctgtact atccgaacgt tctacacttg ctttgtaagg ttcttttgta
    10921 tcgatatcaa cactttgaag tggcttgtac aatgtaggaa tgggtttcat gaccccgcga
    10981 atgacaagtg gttcgccatt ggtcattccg ccttcgaagc cgcctagatt attggtacgt
    11041 cggaaatagc ctctttcttc ttcccatagg atctcatcca tcacttctga gcctggtaat
    11101 gaaccagaag tgaatccgac cccaaattct acgcctttaa aggcattgat actaaccaca
    11161 gcttgtgcga ttttggcatc tagcttcgtg tcccattgta cgtagcttcc taatccagct
    11221 ggaacgcctc caacgagcac ttctacaatt cctccgatcg tatctccatt tttctttgtc
    11281 tgatcgatca aatcttttat tctttgctca actgctggat caacaactcg tacttctgac
    11341 gcttcagaaa tttctttgat ttcttgaatc gagatatttc caggtatttc tgcttggatt
    11401 ccaccaagac aaatcacgtg tcctgctacg atgatgtcaa gttcttccag aattttcttg
    11461 gcaattgcgc cgattgctac acgcatggtc gtctctcttg cagaggaccg ttcaagcaca
    11521 ttccgaagat ctcgatgatg gtatttcata ccgcctacca aatccgcgtg tcctggacgc
    11581 ggacgtgcaa ctcgccgcag tgattggtct ttttcaggca cttctgctac agacatgaca
    11641 gttgtccaat ttttccaatc tttattttct accactaaag tgacaggtga accaattgtt
    11701 ttgccgtgac ggatgccaga cgtgatccga acacgatctt tttcgatctt catccttcct
    11761 cctctgccgt aaccagcttg tctgcgagcg agttcgtgat tgatttcttc ttctgacaga
    11821 ggtaatcctg ctggtagtcc ttcaataatg gctgttaatt ctggtccatg ggattctccc
    11881 gcagtcatat aacgcatctt acagtcctcc taagtaatct ttgaatgtct ctgtgggaac
    11941 aggaacgatt tttgcttgcc caatcttttc tagcaagatg atattcaatt ggcttcctct
    12001 tgctttctta tcatgggtta tcgcgtggaa taattcatct ggatgactta gatcgtacgt
    12061 aatcggcaga tggaattttt gaagtatcct ttctaaagca gctgtcgatc cagttggaga
    12121 caagccgatt ttttctgcat gagaagtgat ggctaccatt ccaatagcta ctccttctcc
    12181 atgactgact accccatatc ctgctgtatt ttcaattgca tggccaattg tatgaccaaa
    12241 atttaaaata agtcgatttc cttggtcaaa gacatcttct tccactactt ttcgtttgat
    12301 ttccaacgta gcagtaatga ttggaacagc atgttccaga agatcttttt cgtctttcag
    12361 ctcgttcagc tgtttccaaa gcgttgcatc tgctatagct gctgatttga tgatttcagc
    12421 gattccttct cgtaaacgac gtaccggcaa agtttttaga acctcaggat caatcaatac
    12481 accagctggc tggctaaatg ttccgacaag gtttttcgct ttgtttgtat tgactgctgt
    12541 cttcccgcca atactagaat ctacttgtgc aagtagcgta gtcggaattt gaacgaaatg
    12601 gatcccacgc atgaacgtcg aggccacgaa tgctgctaga tcacccacca ttcctccacc
    12661 aagtgcaagt atcccatcgc tgcgggtaaa atcattatct gctaaaaaat cgtataactc
    12721 agctgcttgt tctaaagatt tactggtctc acccgccggt acgattgaaa ggactggttc
    12781 aaaattagct tgtctcaatt ggaacatgat tttttctgca tatagtggag caacgtttgt
    12841 atcagtgatc acagctactt tttgaggtct ccaaatcgtt tgaagccatg atccagcctg
    12901 ttctagtgcg cctttttcaa tatgaatatc gtatttttgg ttatcaacat gtacagtaag
    12961 cattcgtttc acttctttct tttaaaaagc tggaattaat cgagtgtctg aatcttttcc
    13021 attgcttctt tcatgatcgc aacttctttc atcatgcgtg agtaagtctt ttcattcaac
    13081 gattggggac cgtctgacca agcatttgca ggatcaggat ggatctctac gatcatgcca
    13141 tctgctccgc ttgccacacc cgcacgagcc attggtggta caagttccca aattcctgta
    13201 ccatgacttg gatcaacaat cacagggaaa tgagttaatt ttttcatcaa tgggacagca
    13261 cttaaatcaa acgtattacg tgtcgctgtt tcgtaagtcc gaatcccacg ttcgataaaa
    13321 atgacaggag atttgtcttc gactgcaatg tattctgcag cattaagcca ttcattgatc
    13381 gtaccggaaa ttccacgttt caatccaaca ggtttacctg ttttaccgac agcagatagc
    13441 agtttaaaat tttgcatatt acgtgcgcca atctgtagga tatcgctgta ctcagccacc
    13501 atatcgatat gcccttcatc catcacttca gtaatcactt tcattccaaa ttcatcagcc
    13561 gcttgacgga tgtatttcaa tccttcttct tctaaacctt ggaaagcata tggagaagta
    13621 cgtggtttga aggcaccacc tcgcagaatt tttgcgcccc cggctttggc cattcgcgca
    13681 cattctctga tttggtctaa tccttcgata gaacaaggac cagccatcgt cacgaaactg
    13741 ccgtcaccaa tttttactcc gtctacatcc acgactgtat tgccaggatg gaattctcga
    13801 gaagtcaatt tgtatgtgtt taaaatacgc acagcatttt ctactccttc atagcgtgta
    13861 aatgctcctt cttgtaaact tcgcgtatca ccttttagtc caatcactac tcgttctgtt
    13921 ccttgatcga ttgagacttt gaatccttct ttttcgatat gatcgacgac tttttttatt
    13981 tgttcttccg ttgcttcttt tttcataatt actatcattg tttttcccgc tttcttttgt
    14041 ttacttatct atcttggctg attttctcta ctttttcaag gtggttttac attaattcct
    14101 actaaatgac cgtgtcctgt tgttctcatt ttcgctcctt ctttcctact tatgacccag
    14161 ataatcaaca aaaaaagatg tccctgtagg aaattgcctc tacagtgaac atcttcaacg
    14221 agccttaaaa agcgctgcaa aaatataaaa tagccactat agatgaattt ctctacgtgg
    14281 ctgtaagtcg tgtttaaaaa tctttagcca tcatagatac aaacctggtt tgtttgtacc
    14341 cacgaagtca tgaatacaaa cctatctaaa atagctaaag taatacgtat tcagttttgt
    14401 aagttttcta gatttcataa aaaatcgctc caaactgatg taagaattgt acctagtata
    14461 gacataaaaa aatcgactgt caatcatttt tatgaaactt tttttaattt tctgatagtt
    14521 aactttgttt ttcagaaaaa taacaattgg ttttattgaa gaaaatagtc atgaacaaaa
    14581 gtatctgaga acttttttac tctcttgttc atgacatata gaataaagca gctttgtctt
    14641 gtaaactccg tttttcaaat aataatctaa agattgctac tgaataataa agccgatttc
    14701 atggtcctct tcgctgctga ttcggtaagg tgactcaaca tccgctcccc agctattgat
    14761 acccccgact cctcttactt ttgcaaaaat cgtaagaacc gttcgtcttt ctggcggtag
    14821 ttcttctata tgtgttgcct gttccagttc ttctgctttg aatggtaaag cggaaaaagc
    14881 aaatggcgta tcctgctgtt caaatcgcaa cgaaaaatct tcttgatctt tatccgtatt
    14941 atccaacgtt tgatttcttg ttagttctac ccatttcgtt tccatatgca tgccgcattc
    15001 ttggggaaca aggtatgggg aaacggggag tcctgccact ttataaatac cttcgacacc
    15061 accagccatc cgatccggat atgtttcccc tgataggcct tcatactcaa aaaattttgc
    15121 tttcgttggc ataatgaacc ttaaacccaa tgcgggtaat tccggtaatc ctttttgtcc
    15181 ataataatgc atattgacaa gcattttacc ctctccagcg atttggtagg aaattgtcac
    15241 ttgggttttt ggtactgtgt tgatttccag tgtaaaaatg atttcaaccg tttcagcgta
    15301 ttcattactt gaatattgat tatttactgg agcaatcggc aaatcgatct ttttattgtc
    15361 caccagtact tctatttctt tgacttttgg atacaatccg gctcctaacc acataccgga
    15421 tttaaatcca aatccgctac ctctgtcatt atcggtcgtt gctcgccaaa aaactggaag
    15481 tgtttcccgg tatagccatt cttttccgtt tttattgagc gattccagtc cgcctcttgt
    15541 ataagaaaaa atataatgcg tattccccga tttgacacct aatgtacagt cgccgaagac
    15601 gattgcaact ttttccgtat ccatatgact tttatttact gtatttttca taataatatc
    15661 ttacctcctg catggcgggt ttttcttgtc catctgcaaa aacgatccca ttccctgaga
    15721 attcatagtc acttggttta tcgtcaaagt caccgccata gcgcatcact tctctgcctg
    15781 tgattggatc agtcacttgg atcgcctgat ctttaaaatc ccatatatag cctccttggt
    15841 acatttcata acgatcaagc aacgtcatgt aagaatccat tccacctaac gaattcccca
    15901 tgtcatgcat atattcacat aagatgaacg gtttttccgc tttattttca aggtagtcaa
    15961 tgatctcttc tggtggcgca tacatgcagc tttttacatc tgaaatcgaa tcttcgaatg
    16021 ctggatttgg aaaattccct tcataatgga caagtcgatc ggggtctact tttttgaagt
    16081 aatcgttcat ttgtcgaatg ttttcttccg cataagattc atttccaaga gaccaaaaaa
    16141 gaatacttgg atggtttttt aatgtttcga aattcgtttt tgctcgatca agaacagccg
    16201 cctgccactg aggtactgca cctggtacgt tgtaagaagg ctcaaatgcg cccatttttt
    16261 gccatgagcc atgggattcg aggttcgttt ccgccatcac atggattcct gcttggtcgc
    16321 ataaataata ccaagtgatc tggttggggt aatgagatgt ccgtacgccg ttgatctttg
    16381 cattttttat gatagccaaa tctttttcca tatcttctat agtgatggcg cgtccttttt
    16441 tcggatgcca ctcatgtcga tttaccccgt tgataatcat ccgttttcca ttgaagtaga
    16501 tgattttatc tttgatttcg attttacgaa aaccgaagga atagtcaata tactccgtta
    16561 ctcttttttc ttcgtctatc gtctccaatt caagcttata taaattgggc tgaaaatgcc
    16621 cccacagtgc cacattttca aatccatcga tgcgaatcgt catttgctct tttaacggat
    16681 attgctgttg atagatttcc ttcccatcag gatctagtat cgctacattc agctgactgt
    16741 ttttggctac ttgctcaaaa gacaaatcta cttcaagttt gccattttga catttgtcat
    16801 ctaagcgagg tttgatccaa agatcttcta aatggttttg tcctcgagca actaagaaga
    16861 catctctgaa gatcccaaaa aatcggaaaa agtcctgatc ttccaagaat gcagctgtac
    16921 ttcttttgta aacctccaca gctagaatat tttcttcttc caaataaggt gttaaatcaa
    16981 attcagacgg agtgaacgaa tcttcggcat acccgataaa atgaccattc aaccaaataa
    17041 acattgcttg ttctacacca gcaaaatgaa tcgagatttg ttttcccttt agaccttctt
    17101 ctaatcgaaa agtcgtcaaa tacgaaccaa ccggattgtc tttagcagct gaaaagatcc
    17161 cttccgcctc tttctcaggg cttgtcgtga aagggggacg gcgaaataca tgtccctccc
    17221 acggatacat cgtattgatg taatggatct tgtcataatt tgctaattca atatgactag
    17281 gaacagtgat ttcatcaaaa gaacaggcat caaaatcttt tttataaaat gtttttggtc
    17341 gtaccgaagg atttggcgaa taacaaaaac gccatgatcc atttaaagac tgtttaaggg
    17401 aggatgtggt ttctacttct tcccttgttg cataacaaac atgatcgcta tgtgcatttg
    17461 attggttcac tctaaaaact tgtggatcat ctaaccattt tatatttgct ttcatacttt
    17521 tttccttctc tctcataact ttttgaaatg aagcagttct gtttggaaat caccttgaaa
    17581 atcggggaag taaagtccaa ctgtcatcaa ttcggccccc gaaaatatcc gcttcgaggt
    17641 ctgttcctga taaagtgcct catcatctaa ccccatcaga tatacttcat ggaacgctgg
    17701 ttgagctgaa gctagtatcc tccctaaaaa cacaatagct tcatcttgtt taggagacac
    17761 aaacatccat gcggcaatat tttcttcaaa aggactcgcc aaacgataat aatggccata
    17821 ctggatcacc ggacgaatcg tttgatagga tataatttgg tcttttactt gctttttttc
    17881 ttcaggagac agctttgtca aatccagttc ataaccaaaa acagcgctca tagctgtttc
    17941 tcctcttgtt ttcaacgaag tagatctgtc ggtctgatga tttggtacag ctgatacatg
    18001 agctgtgatg gacgaaatcg gataagcaag gcttgttcca tattggattt tcatacgctc
    18061 cactgcatcc gtgttatcac ttgtccatga ctgcggcata taataaataa acccggcatc
    18121 aaaccgtcca cctccaccag aacagccttc ccataagatt tccggataat cagttgtcaa
    18181 atgttcaagt agttcataaa gcccgagcat ataacgatgc gctacttctc cttgtctctg
    18241 tgggtcaagg gtaatcgaat agacatctga aagcgaacgg ttcatatccc atttgatgta
    18301 gtcaagagga atcgtatcta aaatctttct catttgtttc tcaatcgtct gccgaacatc
    18361 taaccttgta aaatccagta catgttgtga tctggaagca gaaggcattc tacctggctc
    18421 ctgcataaga aaatcaggat gtgttcgata cagttcagaa tcaaccgaga tcatttcagg
    18481 ttcaaaccat aaaccaaatt tcaatccttt gctatgagca taatctgcta tttcacgtaa
    18541 tccatttgtc aacttgcctt catactcgaa ccagtctcct aatgaagaat tgtccgcatc
    18601 tctttttcca aaccagccat catctaatac gaacatttcg atgcctagct cctttgcttc
    18661 atcaatgatc gccttgattt tttcactatt gaagtcaaag taagtggctt cccagttatt
    18721 gaccagaatc ggccgttcag caaattgatg acgacctctt gcgattcttt cacgtagcaa
    18781 ctcatggtgg atctgactca ttttgttcaa tccctgactt gagtaagaaa ggatcatttc
    18841 aggtgtttga aaagactggc ctgcattcaa ttcccacgaa aaacgatggc tgttgatccc
    18901 accgacgact ctcaattgat tgatctgatc tttttcaagt tcgaaagaat ggttgccgga
    18961 ataaacaaat tgaagtccga tcgcttctcc agtattttct gtcgtatgat gatgaactaa
    19021 agcaataaag ttattcatat ggtgactgct cgttcctcga cggctttcaa atacttttgt
    19081 tccagataaa acagattgcc gtgaaatctg tctttcattg acatgtgctc ctggcaaagc
    19141 aatgacttca tcaaatcgcc tagtatgggc aaagtctagc tggaaactag ccgctttttc
    19201 tagtttgatt gtttctccgg tttcatttct tatctttaca gatcgtgtga tcactgctct
    19261 atcagtaaat atggtataga acaaatcgaa ataaatcgct gtttctctat ccttaagtga
    19321 aatcaccaac gtttgtgcct ctgacttgtc catcacataa gtttgaggca agccttcgat
    19381 ctctggcttc ccatctgtaa tataatggct gtcatatctc agatccagta agtctgatcc
    19441 attcttgcgc tgaatgatcg atgcgggcgt tcgaaagtcc atgctgccat gagaagagta
    19501 ttcttgcggt agtgtatctt tcgacagaga ccggtcagga tttaagggaa catttcctga
    19561 aaatccacga tctcttcggg gataattttt attgtctttg tactgcttga ctggtttgcc
    19621 aaaataaata tgcgccaata cattgctttc ttctatcttt atcagataag aaagaaatgt
    19681 atttcgtaaa tggaagactc ggctcttttc atcaaataag atgaaatttt tatctgtttt
    19741 tctatgcgta atatccatca tttcactccc aacaaaacgg aaaccgttta ctttttttta
    19801 taattcctgt atactgttta ctaaacaatt ttgtcaataa aaatttttta tttttttgag
    19861 gagtgtgtaa aaatggttgg aattagagat gtcgcacgaa aggcaaatgt ctctcctgct
    19921 acagtttccc gtgtgttgaa taacgatcag acgatccatg tggctcagac tactcggcaa
    19981 cggatagtag aggcagctgc tgcgttggat tatgacatca gtactcgtaa atatatcaaa
    20041 aagagaatgc cttcgattgg tgtgatctct acgatcggca aagcgagcga agaacaggat
    20101 atctattaca aacatttgcg agtagggatg gaagaagaag ctcgacgtct gcatttaggg
    20161 atgaatcgaa tctataatct atctgataat cctaaacaat gggaagatct agatcagtta
    20221 ggtgcggtga tcgttgttgg gactgttacg aaagaatcga ttaccgcctt gttaaaacaa
    20281 aacatgcaaa tagtcgtcgt ggataaccct gacatccagc aagaggtcga tatggtgtat
    20341 gcagatcttg aacggatgac taaaaccgta ctggaattgt tcttagaaaa tggtcataaa
    20401 agaatagcct atatcggggg atataaagtc gatatggatg aattcggtgg gaagcagatt
    20461 tctataaatg aaaagaggat gcgtgcctat cagcatttta tgatcgatca tcacttagaa
    20521 aaatatatgt cttatcatct aggtggctgg acagaaaaac aaggtgaggt acttgcgact
    20581 aatctattag aaaatgaatc ccctcttcct actgccattc ttgtcgggag cgatccaatg
    20641 gcaattggtg tctatcgggc attgaaacaa aaaaatatcc aaattggaga agagattgtt
    20701 gtagcaagct ttgataatat cgagacaatc gcaaacctct cccctggctt gaccagtgtt
    20761 caaatcaatg cgaaatcaat tgggcaagca gctgttcgaa tggcattgga gcgaattgac
    20821 ggtatacggg acgaaccaat cattttgact tatcctgcac gattgattgt tagggaaagt
    20881 tttatcccaa gaacaaaaag gtattgaaag agaggttgtg aaaagccgct tcgtttcttc
    20941 atactcaaaa cgaaacggct ttttcacaac ctcttactta tacttattca caaaatccaa
    21001 tgtctgctgg taacaatttt gcgattcttt tagcgtgtaa tcaaattggt attcatgggt
    21061 aatctctttt tttgtatctg tataaaacaa ggattgcacg ggtaccttta attctgtcaa
    21121 ccgattttct aatgcttgac cttgctcctg gaatgagtat gcatttccgt cagttatata
    21181 cgttggcgga aattccttag aaacatggtc agccacacta gcttctttca attgctcact
    21241 cgttttccaa tcttttgttc caatcaacga ccacgcaacg gttttgacga aaaacttcat
    21301 aaatcgatca tccgaatgct gctgtgctgt tagcttcaaa tcaacaggtc cgcaataaga
    21361 aatggttcct ttcagactat cttttggaag tagctgtttg attttcattt gtttagcata
    21421 cgcatcattc gtttgtatag ctgcatattg caatgcgatt tgtgaacctg cactatctcc
    21481 accaaaaaat aattgttcca tgtctagcaa tttgtcgtct ttttcttcag ctaataaatc
    21541 tttgatcagt tcattcactt gaagaacttg attagggtat tctgaatcag gcgctaattc
    21601 ataattcatc gcaaccactg cgatgttggc gtctgaaact aattttgtcg caaattcttt
    21661 gacacccgat ttatctccgc cgacgaatcc tccaccatgt acccaaaata gaacaggaac
    21721 aggccccttg ctgttttttg gatagtagat gtcataagta ttctctttat acttggactc
    21781 atacgtcaaa tctgtttttt tcgccacgtt tttttctgct tgatcgaacg tttttttatc
    21841 agtgatttga acagtatttg aaaacatatg gttgatcaag aatgctccag gtctggggga
    21901 aagctggaag gcaagaaaga ttgcaaacgc gatcccaaga atgattccga agaaccatcc
    21961 gataaattta agaattttct ttttcataag gctccctcag tagttagtat taagcattct
    22021 gattatacca tagtgttatt tcctatcaag ctctcctaga tgatttaatg attttcccca
    22081 aacttcttct gcaatgcttt tgacaaaaga aattttttcc attgttcttc aaacaaaaca
    22141 ttttcttctt ctgttgaagc aaatccacat tgaggactta agcacaaacg atccaaaggc
    22201 agatatcgtg tcgcttcgta gatccggtca atcacttgct ggtgctcttc catttcgcca
    22261 tttttcgtta cagtcaaaat ctaagacaac taatttatct tcagagactt tctctaaaag
    22321 aacaaaactc ccagcacgtt cactatcgta ttctaaataa taggcacgga cattttcttg
    22381 agtaaaataa tgggtctgct acgtcgtcat cccccctgat gccgccaaaa tcgaataata
    22441 atttccgcgt caaacatgta tatttagtgt tgaatcattt gagaatatga aaataaaaat
    22501 ctttttgatc aatcagttaa tcaaattgaa ataacgaaaa atctgagaca gaatgacgtt
    22561 cattctgacc cagatttgat tttgtacaac ccatcagtcc ttattgacaa agagccacta
    22621 aaaagactaa gaaacaataa caaaagttaa cacttcttag tctttcttta gcacgtctat
    22681 ttattaaaga ttttagggcc ttttctcatg tttttacgat cattcttagg tgtttccatt
    22741 tgtttggatc ggcctccacc ttgtttcttt ttgatcaatt ctttcatttt ttctttttgg
    22801 tccattttta ttctccttta acgaatgaag cgactaattc gatatgatgg gtttgcggga
    22861 aaagatctac aggctgaact ttcttcacgg cataacctgc ttctgcaaat aacttagcat
    22921 ctcttgcaaa agttgccgga ttacatgaga tatagacgat tcgttctggt gacatttcga
    22981 ttgctgattc aataaaatga tgatctaatc cttttcgtgg agggtcaact acgatcacag
    23041 atggtttgat ccctttttct tgccattttt tcataacttt ttctgctttt ccgacttcat
    23101 aatgaacatt ttcgatttta ttatttaaag cattgaactg tgcatcttca attgcttctg
    23161 gaataacttc catcccatac accttatcca ctctgtctgc taaagacaag ccaatcgtac
    23221 ctattcctga ataagcgtcg atcacaatgt cttttttatc taactcggca aactcgatgg
    23281 ctgtttggta cagatactct gcttgttgag tatttacttg ataaaatgac tttgctgaga
    23341 ttcgataggt ttttcctaat agctgatctt cgatatagtc tctgccatat aaaacttttt
    23401 ctttgtctcc taaaatcaca tttgtttttt cttcattgat attttggatg accgaaacca
    23461 cttctggcaa ttcttcatga atagcttcag caatttcctt ggatttaaag aatttttctt
    23521 tacgagtaac taaaacgacc atcatttcat gggaataatg accacgacgg ataatgatgt
    23581 gacgaagctg tccttcattt ttttcttcat tatatcctcg tacttggaac cgttgcaaga
    23641 tatctctgac tactttgatt gcttgatcga tgacaggatc ttggatataa aaatcttcga
    23701 tagggactag atcatggcta ttctttttgt aaaaaccggt ggctaactgt ccatcgatac
    23761 ggcgaacagg gatctgtgct ttattacggt agccgaatgg ttctgccatt ccgaccgttg
    23821 gaagtacagg aacttctggc atcttagcaa tcttcgccat tacatgctct acttgttttt
    23881 gtttgaagac aagctgttgt tcatacttca aatgggctaa aggtgcgata cctatgcgaa
    23941 gtaatgcatt gttttctaca ggctgacgat caggtgattg tgtaataaat gtttcgactt
    24001 ttccatatcc aaacttattg cctgctttta ctactagtat ttctacttct tctccaggga
    24061 gtgcattttc gataaataat ggataaccat cgatttttgc tacccccatt ccttcataac
    24121 tcaagtcgac gatttcgact gtatatcgtt cgtttttctt tactatttgc tgttctgtca
    24181 tattttgctc ctttaagcct atttttcaat cctactgaac tctactataa atcagctaat
    24241 tacacaacta aaaccggcac tgaccttact acgttcagca ccggcttttg attaattctt
    24301 ttgattaggt gtttcgtctg ctatttttcc gtcaccgtcg atatcttcat ccgttaaacg
    24361 ttcgacttct tttacgaatt ctttgctgac aacctctaat tcttcttcat ctgtacctgt
    24421 gattgcttca tcaggaatct gatcggtatt ggcaaagaac tcaatgtgtt gatgaagatt
    24481 ttggaaatgc atcggtgctt ccccgccgta ttcaccatct aagttgatca ttactggtcg
    24541 attgatatca tcttctgttt caacgaacaa actgcttgtt ttggtataga ttattcttgg
    24601 atcatcgaca tgtcgaccgc cattcagcat gagtgctgca atatgcaaga tctcaaagat
    24661 atttgctgtc ttcacaatga ttaaagaaaa cttcccatca tccaatttgg catctggcgc
    24721 gatctgttcg aatcctccaa cagagttcgt cagccctagg aaaaacatcg aagcatttcc
    24781 gatatattcc ccttcatcat acttcaagcg cattttgatt ggctttactc gagggagcat
    24841 ctctgctcct ttcgcaagat aagcaagata accaaaaata ctctttagtt ctgatggaac
    24901 ttcataagtc aattctgtca aatagccacc tgcagcgata ttgatgaagt aactgttatc
    24961 agaaaggccg atgtccattt ttacggtttg gtgttttttt atcacttctg ctgctgcttt
    25021 aatattatct ctaggaattt ttaatgctcg agcatagtcg ttcgttgtac cagctgggat
    25081 gatggccatt ttaggacggt gttcaagcgg agcgattcca ttaaccactt cgttgattgt
    25141 gccatcgcca ccagctgcca ctactagatc aaaacctagt tctgcgactc tacatgcttc
    25201 attcttggct gaatctggtt ctggtgtagt tgcataggcg ctggcttcaa atcctgcttc
    25261 ttctaatgcc tgtaggatat ccgccaaatt ttttttcaat aattcttttc ccgaggtggg
    25321 gttataaatt acgcgtgctt ttttcatttt cagcctctat cgtttcgcta attcatcttt
    25381 aagtagctta ttcacgacac caggatttgc ttgtccttta gttgctttca tgatttgacc
    25441 gactaggaag ccaaccgcac gatcttttcc atttttgaaa tcatcgacag attgttggtt
    25501 gttatccaaa atttcattaa tgattggcag tagtttgttc ggatcagata attgcaccca
    25561 accatttttt tcaactactt cttgggcttc tccgccattt gtgatcaatt cacggaagac
    25621 ttttttggcg atttttgagc tgatcgttcc atcggcgatc aaacgaatca ttcctgctaa
    25681 gttctcaggt gtcaattttg tctcagctaa ttccagtttc tcactgttca agtaagcaga
    25741 aacttcaccc atcaaccagt tagatgcttg cttggcatct gcaccatttt ccaaaacagc
    25801 ttcaaaaaaa tcagacattt cttttgtaag tgtcaatacc attgcgtcat actctggaag
    25861 tccaaactca cggatatagc gttcgcgacg agaagctggc atctcaggca aactagcttt
    25921 tactttttga atccattcgt catcgatcac gaatttcggg atatcaggct ctgggaagta
    25981 acgataatca ctagaccctt ctttgacacg catcaaaact gttttattcg ttgtttcgtc
    26041 aaaacggcgt gtttcttgtt ggatttctcc tcctgaaaga agaacttttg cttgacgttt
    26101 ttcttcaaaa gctaaacctt ttttcacgaa agataaagag ttcaagtttt tcaattctgc
    26161 tttcgtaccg aactcttctt gtccataagg gcgaagagaa atattggcat cacagcgcat
    26221 agagccttct tccattttca catcgctgac ttctgtaaat tggataattg atcgcaatgc
    26281 ttctagataa gcgtatgctt cttctggtga acgcatatca gcttcagaaa cgatttcgat
    26341 caaaggcgtg ccttgtcggt tcaaatcaac gtaagaataa ccgccaatac catgcatgtt
    26401 ttttccagca tcttcttcta aatggacacg ttcgatccgg atttttttct ttttaccttc
    26461 tacttcgatt tcgatccatc cgtcatgacc gattggttga tcaaattggg aaatttgata
    26521 tgcttttgga ttatctgggt aaaagtaatt tttccggtca aaatgagtat ctttagagat
    26581 ttcacagttt aatgccaaag ctgctttcat cccgaattcc agcgcagctt tattcattac
    26641 tggcagcacg cctggataac cccagtcgat cacgtttgta ttgctgtttg gttctgcacc
    26701 aaaatgagct ggcgctggag agaaaatttt tgagttggtt tttaactcga cgtggacttc
    26761 tagtccaatg actgtttcaa aattcattcg tctttccctc ctaaaatagc tggttgttgt
    26821 ttatggaatt ctgttgcttg ttcaaacgca tatgccgctt gatacatcgt tttttcatca
    26881 aaataattac cgatgatctg caatccaact ggtaatcctt ctgataaacc tgccggtaca
    26941 gacatacctg gaagtccagc caagttgaca gggatcgtta agatgtcact catgtacatt
    27001 gtgattggat cgttaatgtt ctcaccgatt ccgaatgcaa ctgttggtga agatggcccg
    27061 atgatcaagt cataatctgc aaagactttt tcaaaatctc gtttgatcaa tgtacggact
    27121 tgtcccgctt ttttgaagta agcgtcataa taaccagcac ttaaggagaa tgtacctaac
    27181 atgatacggc gttttacttc ttcaccgaat ccttctgaac gtgagttgac atatacatca
    27241 tctaatgatt tcacattttc tgagcgataa ccgtagcgga taccatcgaa tcgttgcaag
    27301 ttggaacttg cttctgatga ggcaatgata taataaacag ccacaccgta ttttgaatga
    27361 ggcaagctga cttcttccac aacagcacct aatgaacgga atgtttctgc tgctttcaat
    27421 acagcttctt ttacgccagg ggccacacct tcgcctaagt attctttagg taaagcaatc
    27481 ttcattcctt tgatgtcgcc tgtcagtccc tctgcaaaat caggaactga aacgcctgaa
    27541 gaagtaccgt ctttttcgtc ataaccgctg atagctgtca atgctaatgc attatctttc
    27601 accgtacggg tcattggtcc gatttggtca agagatgaag caaaggcaat caaaccaaaa
    27661 cgtgagacac ggccataagt aggtttcatc cctacgatgc cgttaaaagc tgctggttgg
    27721 cggatacttc ccccagtatc actacctaaa gaaactggaa tttgtccagc tgcaactgct
    27781 gctgcagaac caccagaaga gccaccaggt acttttgttg ggtcccaagc attttttgtt
    27841 ttcttgaaat aagaagtttc tgtacttcca cccatagcaa attcatccat gtttagctta
    27901 ccaacaggga tcatatctgc ttgatagatt ttatccatga ccgttgcatc ataaattggt
    27961 tcaaaattgt aaaggatctt agatgcagcg gttgtcaaga tatcttttgt tacgatatta
    28021 tccttgatac caattggaat accagcaagg acgttgcttt catcaatccc tttttcatct
    28081 aaagcttttg cctgttccaa tgctttttct tcgttcaatg taatgaatgc ttcgacctca
    28141 ggctctgttt ctttgattcg ttcaaatgtt gcttttgtca aatcttgtac agtgatttct
    28201 ttcgatacaa gcatatgatg cagttcttct agagaacgat tgtgtaattc tgtcattatg
    28261 cgccagcctc cccattatcg atgattgcgg gtactttgat aaagccgtct tctgtttccg
    28321 gcacattttt caataattca tcgcggttcc atccagcttg cgcccgatct tgtcgcatca
    28381 cgtttactgt ttcaaccaca ttcgacgtaa atggaacacc ttctgtatct acttcttcca
    28441 gcatttcaac catatcgatg attttaccta attggtcggt aaaacttgca agttcttcat
    28501 ctgcgaacgc aagttttgct aatttggcaa cgtgtttcac ttgttcttca ctaatcgcca
    28561 tactacccct tctttctaaa cgagttaaaa actttgctct ctattttaac acaagagtgc
    28621 cgtgtctgaa attgtttatt gaaatttgtc tgaaaaaact catttttcat tcttctactg
    28681 agcgactttt agccaatgca tctgccattt gatcttctgt ccaaacttcg attcctaatt
    28741 cttgtgcttt ggtcagcttg ctgccagcat cttctcctgc taccacgata tccgtttttt
    28801 tcgatacgct accagtcact ttcccgccaa gattttcgat cgtctctttt gcttcttcac
    28861 gagtaaatcg tgttagttta ccagtaagga ctactgtttt ttctttaaaa ggagactcga
    28921 cttcttgcaa ttgggcattt cgaagccctt tgtattcgaa attgacgcct gcttgtttta
    28981 attcattcat caattcatgg acttcttcgt tactgaaata agtgactaca ctgtcggcaa
    29041 tgatatcacc gatcgtatca agcgcaataa tcgactcata gtcactttta ctcaatgttt
    29101 ctagatcacc gaaatgttct gctaaaattt ttgctgcttt cgctccgaca tgtcggattc
    29161 ctaacccgaa aatcaaccgc tcgaccgaat tatctttgct gttgtcgatt gctgtcaaaa
    29221 tattatttgc tgatttttct tttattttgt ccaacgtcaa taactcttct tctgtcaatt
    29281 tgtaaagatc agcaacatct gctactagtt ttttatcata catctgttct agtacgcgcg
    29341 gccccaaccc atcgatattc atcgcatttc ttgaaacaaa gtggttcaaa ccttctttca
    29401 tttgagcagg gcatttagga ttgatgcacc gtaaggctac ttcttcatcc aaatggacaa
    29461 gttcacttcc acaaactgga caatgtgtag gcaattggta ttcttcgctg tctttaggtc
    29521 gtttatctaa cacgacttgc gaaacttctg ggatgatgtc tcccgcttta taaatcagaa
    29581 ctgtatcttt caagcggata tccttcaact taatataatc accgttatgc aggctggcac
    29641 ggcttactgt cgttcctgct actcggactg gtgtcatgat agctgttggc gttactaccc
    29701 ctgttcgacc gactgtccat tcgatgtttt cgattagcgt ttcaacttct tctggcggaa
    29761 acttgtaagc tgctgcccat ctcggtgctt tgacagtaaa accaagttga tcttgtagcg
    29821 agaattcatt cactttgatg acgattccat cgatttcata gggcaaatcc acacgtttgt
    29881 catgatattc ttcaatgtat gaccacactt catcaatcga atgacataga cgtttttccc
    29941 gattcgtgtg gaatccaatt ttttctagct cttctagcgc atcatactgg gtttttgctt
    30001 gcataggacc gaaatcagct actgtgtata aaaaagtgtc cagatttctt ttcgctgtga
    30061 ttttagaatc taactgacgc aaagaaccag ctgcggcgtt ccgaggattc gcaaagatat
    30121 cttttccctc tgcttctctg tcttggttca attggacaaa tgaccgtttt ggcatgaaac
    30181 attcgcctct tacttcgatg ttcattggtt cttttaattt gattgggacc gaccggacag
    30241 tttttaggtt ttcagtgatg ttttctccta cagttccatc cccgcgagtc gcacctctca
    30301 cgaaatttcc atcttcataa cgcaaagaaa cggaaagtcc atctattttt agttcacagc
    30361 aatagtcaac tacacgtccc actgcttttt gtacacgttg atcaaaagct atcagctctt
    30421 ctttgctgaa aacgtcgttc aaactgtaaa gcggaatatc atgagtgact ttttcaaaac
    30481 cttctaatac ttttccgcct actcgttgag tgggagaatc agacgtgatc aaatcaggat
    30541 attgttcctc aattgctact aattctgcgt attctttatc ataaacatag tcttccactg
    30601 ttggtttatc ttctacgtag tattcgcgag accattggtt cagtcttgta cgaagttctt
    30661 ctgctcgttt agcagcttcg tcaatcgtca tttcatgttc catcatttac cctccactac
    30721 taagcttttt caattggcgc aaaggcagcc aaaagacgtt ttactccttg acttgggaaa
    30781 gccacatcta gttctagatc cttcgacgtc ccgcttactc ggacgactgt tcctagaccc
    30841 cattttttgt gtttgacttt atctccaggt ttccagctgt tattttcccc tccagtagca
    30901 cttttagagg gaacaaccgc tgtctctggc tgtttatagc tatatgctgt ttttttagcg
    30961 aatacaggtg tttttttagg cgtaggacgc atgccttcga tttccagtaa ctcctgatcg
    31021 atttcttcta caaaacgaga aggtcggtta tattgcgtcc gtccatataa tgttctggag
    31081 aaagcatttg ttaaatacaa cgcttcttct gctcgcgtga tccccacata tgcgagacgg
    31141 cgttcttctt ccagttcgct ttcttccatc aatgctcgag ataaaggaaa aaccccctct
    31201 tctagaccaa tcaggaatac aactgggaat tctaatcctt tggctgcatg caaagtcatc
    31261 aatgtcactt gggaagcatc ttcttctaaa ttgtcaatat cggaaacaag tgccagatca
    31321 tttaagaaga ccgttagttt ttcttctggt gcatcagcgt cttcttcatt ttgctgttcg
    31381 aattgtttgt cgaattcttg tgtgaccgtt aaaaattcct ccaagttttc gatgcgtgct
    31441 tgtgcttcta atgtattttg gatttttaag tcttctagat atccgctacg atccaaaacc
    31501 tctttcgtca attctgtcac tgtcaagtat gggatcatct gagtgacttc ttggatcatc
    31561 tctccaaatg cacctaattg ctgtcctgct tttccaccga tatttgccag atccacattt
    31621 tgcgctgctt caagcagtgg ccattcatga agagaagcaa aactgcgtag tttttcgata
    31681 gatcctggtc cgatgcctcg tttgggcgaa ttaacgatac gctcaaaact gattgaatct
    31741 tgaggatttg ccagcacatt caaatacgct aaaatatctt tgatttcttt acgatcgtag
    31801 aacttgtgcc ctccaaccat tttataagga atatttgctt tcaacagagt ttcttccatt
    31861 acacgagatt gtgcgttcgt ccggtacaag atggcaaagt cgccgtaatt ccgatgattg
    31921 cttcgaatct cttcttgcat ccgatctacg ataaaacggg tttcgtctcg ttcattatct
    31981 gcacggtagt aagtgatctt gtttccttct ttgttttctg tccacaagtt ttttggtttt
    32041 cgattgctat tgttttcaat gacttggttt gctgcgctaa ggatgttttt cgtggagcga
    32101 tagttttgtt ctagcaaaat tactgcagca tctggataat ctttttcaaa atccaagatg
    32161 ttctgcatat ctgcaccgcg ccagccgtaa atactttgat ctgcatctcc cacgacgcac
    32221 aggttcctaa atctacctgc caataaattg actagcgtat actgtgcgtg atttgtatct
    32281 tggtactcat ctacatgaat ataatggaat ttgttttgat aatatgtgag tgaatcagga
    32341 tgttcttcaa ataatcgaat cgtattcatg atcaggtcgt caaagtccat acattgatta
    32401 tattgaagct ctttttggta agcagcataa cattttgccg caatctcttc gtaataactg
    32461 ccttgcattt ttgcaaaatc ctgaggggtc tgcaggctgt tttttgcttg agagattgtt
    32521 cctaatatac ttcgaggatc atattttttc ggatcaatgt tcagttcttt tagtatccgt
    32581 ttcatcaagg tcagctgttc agaagaatcg atgattgtaa agttccggtt atacccgata
    32641 aaatcaacat ctcttcttaa aatacgcaca cacatcgagt gaaaagtcga tacccagaca
    32701 tcttcgcctc cagatgcgag aatcgcattg acacgttctt tcatttcttt tgcagcctta
    32761 ttggtaaaag taatcgctag gatgttccaa ggattgactt ctttttcctc aatcaaatag
    32821 gcaatgcggt gtgtcagcac tctcgtcttt ccacttcctg cacctgccat tagcagtaat
    32881 ggtccgtcag tgtgaagaac agcttctttc tgacgggggt tcatcccgtt taataattca
    32941 gctttggatg acattaacaa catcctttct tttatcaatc ttgttaatta tagcattttc
    33001 ttggctttca ttaaactagc tagttcaaaa tcatttgttt ctttttatgg atttttcctt
    33061 gtcaattcgt tgatttcgcg ctaaattaaa agaaagcgag gcgtttgaat ggaaaaaaaa
    33121 ggaaaaatca agaaattaga taagactcag atatatttta ttctaaaagg aatatttgtt
    33181 ggactgctga caggaatcgt cgttagcctg tttcgattat ctatcgaaaa gctaagcgat
    33241 ttagttcgaa gtatctatga aatgagtcgg gaacagccga tttacttaat tggcctagct
    33301 atttgctgca tccttgcagc atttttcgtg ggttatctgg tcaaaaatga accggatatc
    33361 aagggaagcg ggattccaca agtagaggga cagcttcgcg gggaattatc aatgaactgg
    33421 ttctctgttt tatggaaaaa gttcattggc ggtgtacttt cagttggtgc gggccttttt
    33481 ctaggtagag aaggaccttc tatacagctt ggcgcatcca ttggacaagg agctggacaa
    33541 ttgtttcgga gtccatcttc agaagaaaag attttaattt ctagcggtgc aagtagcgga
    33601 cttgcagcag cattcaatgc tcctatcgca ggattactct ttgttttaga agaaatccat
    33661 cactcctttt ctccacttgt ttggctgaca tcatttgctt cagcaatcac tgctaacttc
    33721 gtctctcttt actttttcgg cttgagacct gttttatatc taggtgacct tccttctttg
    33781 ccgttgaaat attatggttc cttagtgatc ttaggagtac ttctaggcat cttaggtttt
    33841 atttatcaga aggtcttgct ggctttgcca aaattttaca accgattgcc tttaccagct
    33901 tattttcacg ggttcgttcc tttcttgctg attttgccaa ttggttattt atggcctagt
    33961 actctaggcg gaggcaatca aatcgtttta gcttttggac atgcttcctt gccaatcatt
    34021 atgattatcg gtttgtttgt tcttcgattc gttttttcca tgatttctta cggtggtggt
    34081 cttccagggg ggattttcct tccgatattg acattggggg ctttaatcgg tagcttttat
    34141 ggaaacatta tggttgattt cgggatggat ccaatctaca tcaaggattt tgtcgttatt
    34201 gccatggctg gttatttcac agcgattgga aaagcaccgc tgacagcaat tattttagtg
    34261 acagaaatgg ttggctctct taatcatctg atgcctttag gattggctgc tcttgttgct
    34321 tatatcgtca atgaccttct cggcggtaat ccaatttacg aatcattatt ggaacgtcta
    34381 cttggaaata ctcagaccgc ctcactaaaa ggtgcaagga caacttttga ttttccagta
    34441 acggcagaga gttctttaga cggattaatg gtacgagact tcaattggcc taaaaatatg
    34501 ctgctaatct ctatacgcag aggaaatcag gaaatcttga ctcacggtga tacgatcatg
    34561 aatgtaggag atattttggt tatcttgact gatgaagcaa acttgccaag aatcaagcag
    34621 gaaatcgagg ctaaatcttc tatcacaaat ttgaagcaat cattttaacg aacatggaaa
    34681 aactatttta caacaactat tcatctacac tacttgattc tatatgattc tataaaaaaa
    34741 gaagagactg ggaaaaacca gcctcttctt ttttatttct atgcttctgc tgctgcagga
    34801 gcttttctca ataaaccata aatcacacca gatacgactg ctccgatagc aataaacacc
    34861 aaatacatga ccgggtgact cagtaagaat acaacgaaaa tcccgccatg aggagccagt
    34921 aatttgatcc cgaaagctcc gactaatccg ccagttaaag cagaaccaat aataaaactt
    34981 ggaatggcac gaatcgggtc agctgctgca aatggaatcg atccttccgt gacaaacgat
    35041 agtcccatca cgatgttcgt caaaccagca tcttgatctg ttttgctgaa tttattctta
    35101 aacaaacgtg tagcaacgaa aattgccaat ggaggtacca ttcctccagc cataacagaa
    35161 gccatcacga cacttccgcc agttgcaaca gtcgtagcta aagttgctgt accaaacaca
    35221 taagcggctt tgttgattgg accgcctaaa tctgccgcca tcattccagc taataatgca
    35281 ccaagtaaag cagcattcga accactcata cttgtcaaga aaccgttcaa tgcatcattg
    35341 attgctttca tagggacatt gaccagcaac atcaagaaac cagtaatcag taagccaaac
    35401 actggataaa agaggatcgt tttaattcca tccaatgatt ttggtaagtt cttgaataat
    35461 ttacgtaaaa atacgatgac ataaccagct aagaatccac caatcagtgc acctaagaat
    35521 cctgcaccgc ctgtattagc taatgcacca gcagcaaatc caacgatcaa accagggcgg
    35581 tcaccgatac ttgaagcaat aaatcctgct aataccggca gcatgaaacc aaatgcagct
    35641 tgtccgattt ggttgaacca gctagcagct tgattgtaat tccctagatt tgataattga
    35701 tcatgtggca cgccaataaa ttggtcgatc atgaaagaaa gcgcaatagc gattcctcca
    35761 ccaataacga aaggtaacat gtgtgatacg ccgttcatca aatctttgta aattctttgt
    35821 ccgatagtac catccgcatt tccttcttct gaactgcttt cttttccatc accatggaat
    35881 actggtgcag taccactaag ggctagattg atcagctctt ctggtttacg gataccatca
    35941 ctgacaggac gattgatcag ttcttttccg tcaaagcgat tcatctctac ttttttgtct
    36001 gctgcaacga ttacaccttc tgcacgggcg atgtcttcag cagtcaatcg gtttttgatt
    36061 ccttctgaac cgttcgtttc gactttgatc tccacaccca tttctttcgc ttttttcttc
    36121 agagcatctt ctgccatgta agtgtgagcg atccctgttg gacaagctgt aacggcaaca
    36181 acgaattttc tttctggatg agcagaagct tctgcagctt gtgtttcttg ttctgctttt
    36241 tcttctgctt ctttttgctc ttcagctgtt tggaacaagt cttggacttc ttctggtgta
    36301 tttgcttctt ttaattttcc tacgaaatct gcatcaatca gcaatcgaga tagtgctgct
    36361 aatgcttgca aatgtgtgtc gtttgcgcct tctggagctg cgatcatgaa aaacagataa
    36421 gttggctgtc cgtctaaggc ttcataatct actccttttt ggctttttgc gaataaaact
    36481 gttgcttctt taactgcact gtttttcgcg tgaggcatgg cgattccatc accaagacct
    36541 gtagaagttt gtgcttcgcg ggctagaatt ccttctttat atgtttcgat atcggaaatc
    36601 cggccggcat caaacatttt ttggaccatt tcatcgattg cgcctttttt atcagtcgct
    36661 tgcaaatcca tgatcatcgc ttctttgacc attaaatcct tgatattcat gattatcctc
    36721 cttgaaacta atcaattttt gtgatttcaa cttctggcag caactcatca atcaattcgc
    36781 gagctgccaa gtcatcagaa aaagctgttg cgcttccgca agcaactccc catttaaagg
    36841 cttcgattgg atctttcgta cggctgtaag ccccaataaa gccggcaatc attgaatccc
    36901 ctgcacctac tgaatttttc aatgggcgaa ctaatacatt cgttttataa gttccttgtt
    36961 ccgtgaagag caaagcaccg tctccagcca ttgagatcag cacattctgt gccccttcag
    37021 ctagcaattt tttaccatac ggaatgattt cttctacaga ttggaaggtt gtattgtaaa
    37081 gctcagctaa ttcgtgattg tttggtttga tcaacaatgg tttcttaaca agtgcatttt
    37141 ttaggtcatc acctgttgta tcaatcacga aatctgcacc tttttctcga atgatatcaa
    37201 tcagttcttg ataaaatcct tttcgcaggc tagccggcgc gcttcctgac aatacgacga
    37261 tatctccttg tcctactgtt cctaatgctt gcttcaactc atcgatttct tcatctgaaa
    37321 tagatgggcc caaaccgtta atttcagttt cagtatctga ttttagtttg atattgattc
    37381 ttgtatcttc ttttacggtt gtgaacaaag actggatttg ttctttttca agccacttcg
    37441 aaataaattc gccagtgaac cctcctaaaa accctagtgc tgtagattga gaatcgatcc
    37501 gtttcaaaat acgggaaaca ttgatccctt ttcctccagg taacttgaag tcttccttca
    37561 ttcggttcaa atcgcctagt tttaacccat ctacgcgtac gatataatca attgatggat
    37621 taagtgttac tgtgtaaatc attgtattgc ctccttaatt gttgtctttt cacggaattc
    37681 attaacgaat tctaatggac aacgctcggt tatgatcgtg gctgcttcca aaggtgcaac
    37741 agaggtgaag gacaactggt tgaatttggt atgatcaatc aatacaaatg tctcttcgga
    37801 atttttcatg gctaaacgtt taacagctgc ctcttctggg tccggagtcg tgaatccttg
    37861 ttcaagatgg gcaccgttca ttcccataaa tgctttatta aaatgaaaat tttttagttg
    37921 ttctatcgca ttagatccta aaacagcatt agttgccagc tttatcgttc cacctaaaat
    37981 aatggtagca agctccaaat caactaaatt tgccgcatgt tgaacggaat ttgtcactac
    38041 tgtgatctgt tttccttgca gaaaaggaat catttctaac gtagtagagc cagcgtctaa
    38101 ataaatgaca tcttcgtcat taatggtttc agctgccgat ttggcgattt gctgtttttc
    38161 gtgaacgttt ttgagtgatt tttcactcat attctgctca aaattcaata attgctcttt
    38221 cttagctccg ccatgaactc tttctagaaa cccactattc tccagctctt gtaaatcacg
    38281 tcttatcgtt gattcagaag cattaaaaag gtttacaaga tcttgtgatt tcacgatttt
    38341 ctgctgttca agcaagtcta ggattttttg tctacgttcc tctgtaagca ttttcacgat
    38401 cacctcaata caaataatag catatttttt ttctactcgc aatataaatc agtcaaaaac
    38461 gttcataaaa attataaatc agtcaaaaaa aaataaaaaa ccagtcaaaa agactggttt
    38521 tttatttttt tgtctatcat caagccgttt tatcgttttt tattttcgct tcttgttttt
    38581 ttcatataaa cagaagcagg ttttctttcc ttatgaagaa gataataata aagtcccatc
    38641 ccgccaaaca tgaccaaaaa accgatgact gatcgaatag gaaaattagg aacaaaaaag
    38701 agacagacgg ataataatga tgccggaacc attattcgat aatagagttg tttatccatt
    38761 ttcttcacct catatttttt gtaaagtaat caattgttct aattctcggt aatctaaaaa
    38821 ttgcacacgc agatgctgct cacctttctt gacatcgaat tggatacttc gccgcttttt
    38881 ctttattcgt ttgaaggtaa catcagagag tctatgtttg atttccttta acggtaattc
    38941 tgacagggat tctgaaggaa catagattct taaggataaa agatactctt gatatttttc
    39001 atctgttacc tctacttcta gatattccct aatataataa caataagctt cgattccatt
    39061 atccaaagca acagtcggat cgataacttt atagcacatc atgcgcgagc gattctcgtc
    39121 aacccaagga aaatacgcct gagcatttag tgttccgcga acacgccttt ctttataatc
    39181 tccttgttga atatcataac tttttgttac aaaaaatgaa gcattctttt taggaacagg
    39241 ttgcatttgt gcattctgat actggacaga ttggatcgta tggtcagtgt aaatgtattc
    39301 aacgaatggc ggtttcaata aaccgacacc attgtcccaa gcaagatgat caaacccaag
    39361 ctggtcccta aaataggatt gaaacatttg attgtttggc ttttgccagt taaaggggtc
    39421 tcgataaagc tggatacata tgacttcgtt ttctaattcc ttcacttttt ctacttgttg
    39481 gatgtcgaga aaaatcggtt tagggatgat ttgatgataa tagcgactat aatacatttc
    39541 ccaacacgaa gtgaaacata aaccttggta aaaaagatcg tatcctggaa attggttgca
    39601 atcgactact acttccccgt tttgttgttt cattttaggt aaatgttcga tttcatcctt
    39661 tttctcaaac aatagccgtt gagagatctg ttttgtattg tgatagataa actcgctata
    39721 agctcgcata taggcgaaca ccccatgagc aatcattttt ttctgaatga agtctcgaat
    39781 caaaaattga ttttctttga aaacagagat agacaataca ttttttatca ataattgatt
    39841 atcttccaag cgaaaactac attcgttctc gtcatttcct acaactaacc aactttcgtc
    39901 tcttaccgat gctagcatta ttttttcttg aagctttcga agatcatacg gatccgcttg
    39961 ttgtgtgaaa gagcggataa atgttggctg gatcaacaga cgtgtcaaaa tagcccaatc
    40021 gcttatttcc tgtttttttt cttcttcatt taagtctgtg agctggatag tcatcaataa
    40081 tttatcttcg ccaatcattt tctcacctct ttaaaatctt tttataattt aattataacc
    40141 aacgataaag aaaaactaaa actttatgtc ttagaaacca atttggacga ttacatgata
    40201 gactaagtaa aaagaaacaa agaggtgttt acaatggggt tgaaatttga acgtacagat
    40261 aatttagata aacttttcga atcatttgct gtcgatccgg aaaaaacagt tgcaccaaaa
    40321 gaagagatcg atcgatttct aaaaccacag ccacaaaatg aaaagaaaaa agacaagaaa
    40381 caaaagtaag ttaagctcaa aaaaagactt accagccaaa cttttatgaa agagtttgac
    40441 tggtaagtct tttttattct ttttatgatt caattgcttg ttcgattgct gcccacgctt
    40501 cttcttttcc ctgttttgta acggaagaaa agagaataaa cgtgtcattg cgatcaaaat
    40561 ccaacgcttt tttgatttcg ctctcatgct tgttccattt accacgaggg atcttatctg
    40621 ccttagtggc aacaacaatt acagggatat cataatactt caaaaattga tacatctgga
    40681 tatcttcttg agaaggctta tgacgcaaat ctactaaaga aacgaccgca cgtagctggt
    40741 ctctagtcgt taaatatgtc tcgatcatct ttccccattt tgctcgctca gttttggata
    40801 cttttgcata cccatatccc ggaacatcga caaaatgtaa tgcgttctcg atcaaataaa
    40861 aattcaatgt ctgggtcttt cctggcttac cggaagtacg ggctaaattc tttcgatcaa
    40921 tcaatgtgtt gataaaagaa gatttcccta catttgatcg tcctgccaga gctatttctg
    40981 gcaattgtgt atctggatat tgttttggtg ccactgcact tatgataatt tcagcttgat
    41041 ggactttcat ggtctctctc cttaacaagg tgatgaataa agcaagcggc tgtcgcaaaa
    41101 gccaaaatga cttttacggc agcctctttt catcaacccg cttttttctc tgaatcttta
    41161 tagattactg ttggctcacc agacaattca gctgcttctt ttgtgataat cactttttcg
    41221 atgttttcat ttgaagggat atcaaacatc acatccatca tgatttcttc aatgatggaa
    41281 cgaagtcctc gagcaccggt attgcgttcg attgcttttt tcgcaatggc tctcaacgct
    41341 tcaggttcga attcaagttc ggtattatct agagaaagaa gtttttgata ttgtttgact
    41401 agcgcatttt tcggctcagt caagatccgt accagatcat ctgttgtcaa tttctctaaa
    41461 gctgccataa caggtaatcg tccgataaac tcagggatca atccgaattt tagtaaatct
    41521 tcaggaatga tatgctgcat gacactttcg tcttcagaaa gtttttggtt ttgtgtacca
    41581 aatccaatcg tcttttcgcc catacgattc ttcacaatcg tttcgatgcc atcaaatgca
    41641 ccacctacga tgaacaatat gttcgtcgta tcaatctgaa taaattcttg atgtggatgt
    41701 ttacgtcctc cctgaggtgg cacgcttgca acagttcctt ctagaatttt cagcaaggct
    41761 tgttggacac cttcgccgga aacgtcacga gtaatagata cattttcgct tttacgcgca
    41821 attttatcga tctcatcaat atagatgatc cctttttctg cacgttccac attgtaatca
    41881 gcagattgaa gcaatttaag caaaatgttt tctacatctt cccccacata accagcttct
    41941 gtcaaacttg tcgcatctgc gattgcaaaa ggtacattca atgtttttgc taatgtttgt
    42001 gctaaaaatg ttttaccaga ccctgtaggt ccgatcaagc agatattgct tttttgcagt
    42061 tcaacatcat ctgtgttttc ttgtgcttgc tgattgacac gtttatagtg attgtatacg
    42121 gcaacagcta acgagcgttt tgcgcgatct tgtccaatca cgtagttatt caatacttca
    42181 agaatttcta gtggtttagg gacttcagtg aattcgcgta cagcttcttc ataaaattct
    42241 tcatcaatga tttctttaca taggtcgata cattcattac agatgtagac ccctggacca
    42301 gctacgatct ttttcacttc ttcttgggtt ttcccgcaaa aagaacagcg tacggtctca
    42361 ttgctacttg gattgtcata catggtcttc accccttaac ttgcaaaaag tatgcaagaa
    42421 actatcaaag actttacagt cttttactat cataacatag tttagtaaaa agaaaaagtg
    42481 tttaacaaag gatcaactga cctatacctt tgcatttttt actcttaaca aaaaataagg
    42541 aactgtgaca aaatcgtgtc acagtccctt atttcgaata aacaattttc tagaagtagc
    42601 ttcttcagaa atgatttatt acttgatttc tattctttcg cttctgtcgc tgtacctgtg
    42661 atcaattcga ttgctttttt cattgtcaca tcatgttcca gcatatcttc tgtcaacacg
    42721 cgtttgattt gttcgattgg catgttgtat gtttctgata attcttggat ttctgcattg
    42781 atttcttctt ctgttgcttg aagattttca gcagctgcaa ttgcttcgat cacaagattt
    42841 gttcttgtgc gcatttctgc ttcaccttcg aattgtttat gcaagtcttc ttctgtagaa
    42901 ccagttaatt gatagtacat ttcaggagag ataccttgac gttgcatgtt gttcaagaat
    42961 tcgtccattg aacgatgtac ttcatcatga accatcacgt gtggcaattc aacgatttct
    43021 gcgttttcaa cagccatacg gatcgctgct tcatcttttg catcgtccgc tgctttttct
    43081 tttgtttcta ctaattcttt gcgatatttt tctttcaatt cgtctaatgt tgatacttcg
    43141 tcatcaacat cttttgcgaa ttcgtcatct aattcaggca cttcttttgc ttttacttca
    43201 tggattgtca ctttgaagac tgcttctttt ccagcaagat cttctgcttg ataatcttct
    43261 gggaaagtta catttacatc tagactttca cctgatttat gaccaactaa ttgatcttca
    43321 aaacctggaa tgaatgagcc tgaacctaat tcaagtgagt aattttcgcc ttttccgcca
    43381 tcaaacgctt cgccatctac aaagccttcg aagtcgatta ctactgtatc gccattttca
    43441 gctgcagcat cttctttgat aactaattca gcttgtgctt cttgttcacg tttgatacgt
    43501 gcatccacgt cagcatctgt tacttcacgg tcttgttttt caacaactag atctttatat
    43561 tgtcctaatt ttacttctgg tttcactgtt acttcagcag tgattaccca gtcttgacct
    43621 ttttccatgc tttcaacatc gatttttggt tgagaaacag gatcgatgcc agcttctttg
    43681 acagcagctt cataagcttc tggtaataca gcattcaatg catcttcata taaagcttct
    43741 tcaccgtaca tacggttgaa tacttgacga gaaactttcc ctttacggaa tccaggtacg
    43801 ttcaagcttt ttttcacttt attaaacgca gttgttaatc ctttttggat ttcgtcttgc
    43861 gcaatcgtaa attttaaaac accatcattc gtgccttttt tttcaaatgt tgcagtcatt
    43921 taattccctc cgagtttaga aattcatttt atacatcaaa aacgtttcat gcataccttt
    43981 aaatagtaca ctaacccttt caaattgtaa acatattgaa tggatagaat ccttgttttt
    44041 cataacattt ttatcttttt cactgataaa atctaatgga agaagatcat ttgctgcaaa
    44101 attttttctc ttttttttaa aaaatcttgt ttttcatctt ctgtaccttc atacatcgtt
    44161 tttcctgtac acgcctctac agtcagttga aaccagcgct tcgggtcttc gatgtatgta
    44221 tcatagacag gataaacaat tgcagattgc aacgtgaatt cttcatttaa cacggaacta
    44281 agcagcgcat cttcattacc gtaacgatct gaaaatacac ataattgctg gtaacttgcc
    44341 tgctgctgcg gctttggcag atcttttggt atgactttga ctaacttttc ttcaatcgtc
    44401 aaatagaaaa caggatggca ttcgttcaat tgcctaagtg tctccagtaa ttttgccctt
    44461 gctaaaatat ggacctctgg cgatacaata agtttactcg ctgtttggat aaactcatga
    44521 taaggaagct gttcgatctc atcaatagac gcaagctgac gtgcaggttc caacgaagga
    44581 agttcctccg atttattgtg gagtgccttg atcttctgcc tctccatttg tccggataat
    44641 tcttctgcaa attggatttt ttcaatgacc cgctgctcga aagcttcata aaaatctgta
    44701 cttgctatca attttctagc atataaaaaa tcttgtgtac tgattaacaa gtcaaaataa
    44761 aattcagcaa actcctcatt ttgaagatac tgtttttcat gcaagagtgc ttgcttcaat
    44821 gcttcttttt tctcgtccaa ctcgtaaaga caaaaaacaa gcaggctatt agcctcaaag
    44881 ctttctttca actcgtaagc tcgttgaaat aattcttttg cctgctgata ttgctggttt
    44941 gctagtgctt gttgtgctac tcgcattaaa ttctcatatt tttctggaaa atcaatcggc
    45001 ttcacgcagt gtcctcctct tgctcatgtt cagctcatgt tcaatagtag caaaacaaaa
    45061 aaagcatgac aattaaaaat aactgaagca ccctctaaaa gctagatttt agatctgact
    45121 tttagaaggt gctttcaact gttactgctt tttattgctc atcagctgtt gacttcctgg
    45181 ttgaatgctt tgatcagatt gatcgtaaca acacttgtat tagtgaaaaa atcgcctaga
    45241 tgttgctttt tctgattaaa gattgctgga agatacccta acatcagcaa aggaaatttt
    45301 agaatgaacc ggcaagcacc ttctctaact aaaacggttg accagctaag ttcttcttca
    45361 tcaaagctga tgactcgaat accaaagatc attttcccaa tcgtttgacc atgattgaat
    45421 ttcgtcaata aaataaaata cgctagataa ataagtaagg ctgtgaatcc gtagatactc
    45481 agataagaat ctgaaaaatt aagccaacct agatttttgg caataccaag tgttaaacgc
    45541 gtaatagctc cgatacacaa aagatcgacc aagaaagcaa acattcggat aaaaaaacct
    45601 gcatagaaat acttaggaaa atcatttgct tttggcggtt catttcttgt gtccgtatac
    45661 tttttccatt tacgttgttt ctttttgatt tcttcgggcg tcaaaggctc tctttcaaaa
    45721 gagctcagta ccttttggga aaagttggag tcaggtccta cagcaggctg ctgttgctta
    45781 tctttttctt gttccttatt ttcatttgaa agctctgaca tgcttactca cctccgtaat
    45841 aatacattgc ttttggtgat tccgctgtcc ctagattctc aagaacggat aagatctgac
    45901 tagtctcaga aggcttcaat ccctggaatt ctgctagttt acttcctaac catgtactag
    45961 caaacccaga tggcgtggaa gaatattcta ctagttccgc atcttcaagc tgttgttcct
    46021 ttcgcatagc ttttaaagca tcttcaggaa atcccaattc atcgactaaa cctacttctt
    46081 ttgcttggac accatcataa atccttccat cagcaatttt tttgacttct tcttcagatt
    46141 tattccgtcc ctcgctgacg attgctacaa aacgactata tgcgctgtcg atatatgctt
    46201 gaagcaccgc ttcttcttct tttgtctctg gtcgcgttcc tgaacccata tctttcaacg
    46261 ctccgctttt aactgttgta tcttccacac ccagtttttc tagaagtcct gaataattca
    46321 atcctgacat gatcacacca attgagccgg tcactgtttc ttctgttgca aagattttat
    46381 ctgcttgagc agaaatatag tagccaccgc tagctgccat gtttttcatg ctgacataca
    46441 ttgggatatc atgttcttta cgaatcgtat ccaatttctt agcgatttcc gcactttcgt
    46501 agacaccgcc accaggagaa tttacttcta aaaagatacc tttgactgtt ggatcttctt
    46561 caatcgcctt cagttgttcc ataaaatttt tatgattgta accttcagaa gcaaataaac
    46621 ctgaagaccc tcccgcagca atcgttccat ctactgataa ttttacgatt ttttgcgtac
    46681 tgtctccctc ttccaacaca tttgaagcta gttcttcatc cccatataac caactgttca
    46741 atccctcaat ttgatcgttt tcctgaggct tagtcaaact agctgaaact aacgaaacca
    46801 caaataatcc tgcagcaatc agaactgctg cccaacgtct cttattcatt ctttctcctt
    46861 tctaatacaa gttttttatg acgatcacag tttctgactg ctcagaagtg tcgaaccgct
    46921 ctgctttttc ttcccgcgca tacccggaaa acgactcttt tgtcaattca tcttctaccg
    46981 taaactcacg agcttcagca acttccaagg catcaggtgc gatttcttgg atgctatccc
    47041 agccagtatc taaaaatatt ttcgtatcat ctgatacacc agctgatgct tcgaatttgg
    47101 acaattgttt ttttaacatt cccagtgtca tgatctcaat ttttgaatcc atttttactc
    47161 ctcctctatc cgattacttt ctattgtacc gaactcctga aaaagatgat agataaaaac
    47221 ccattatttt ttgacataaa aagagcattt gacaaagcat ttgatatata ccaatttatt
    47281 ttttattctt tttttgttga caagaacatt cgcaaaaggt tatgatttta aatgtttcca
    47341 gataaaaaac aaaagaggag gatagttata ccttttagga tagcgccagg tctgtgtaaa
    47401 cagatgacga ggagagggtt tatcgaaaga ttcggcggat ggccctaggg actgcactct
    47461 acagaaaatc cacaaaaaat atctgcaaag ataaaacaaa aggattttcc tgcagctgga
    47521 agcattcata cgaattcatt atagaaagta ggatgttttt tatgtgcgga attgttggaa
    47581 tgattggatt aaaaaatgta acaccaggat tgattgacgg tctagaaaaa ttagaatacc
    47641 gtggttatga ttcagctggt atctttgtct cagatggcac aactgattat ctggtcaaag
    47701 cacaaggcag aattcaaaat ttgaaaaaca aaataaatat tgatactaca ggaaatatag
    47761 gtattggtca tacacgctgg gcaactcacg ggcaaccttc tgaagaaaac gcccatccac
    47821 atacttccca aagtggacgc ttcgtgctcg ttcacaatgg cgtaatcgaa aactttgaag
    47881 aacttaaaat tgcttattta gcaaatgacc actttattgg tgagaccgat actgagatta
    47941 tcgctcatct aattgaaact ttcgcgaagg atactacaac gcaagaggcg tttttaaaag
    48001 ctttgcgggt catcaaaggt tcttacgctt tcgctttgat tgatcggaca gcacctgatg
    48061 ttatttacgt cgctaaaaat aaaagtccac tattaatcgg actcggcgat ggattcaatg
    48121 tgattgccag cgatgcaatg gctatgcttg ctcatacgaa ggaattcgtt gagattgaag
    48181 atgaagagat ggttaccgtc acatcagaaa aagttattat tcaaaatttt gcaggtgaca
    48241 tcgtagaacg ttcttcattc gaagcacaag tagattcttc agatatcgag aaaggtacct
    48301 atccttttta tatgctgaaa gaaatcgacg aacagcctat tatcatgcgt cgtatcgctc
    48361 aaaaatacgt aacagaagac aatcgtgtct ctcttgatca aaagctggtc gatacattgt
    48421 ctgatagcga tcgaatctat atcgttgctt gcggaactag ttaccatgcg gggttagcag
    48481 gtaaacagac tctggaaaaa ttgacacaga tccctgttga ggttcattta gccagtgaat
    48541 ttggctataa cacacctctt ctttcaaaaa aaccattctt tattttcttg agtcaaagtg
    48601 gcgaaacagc agatagccgc caagttctgg taaaaatcaa ccgtctcggc tacccttcac
    48661 ttacgattac aaatgttgct ggttctactc tttcgcggga agcatccttt acactgctat
    48721 tgcatgctgg acccgaaatc gcagtagcat caacgaaagc ttatactgca caaatagctg
    48781 tactaacttt attagccaaa gctatcggtg ataaaaaaga atttgaaact tctcttgtat
    48841 tcgatatcac tcatgaattg agtttagttg ctaatgcgat ggaatcggtc atcgcccaaa
    48901 aagattattt agaagagttg gcagaagtat atctcagcga tacaagaaat gccttttaca
    48961 ttggacgtgg cgctgactac aacgtttctc ttgaagctgc tttgaaattg aaagaaatca
    49021 gttatatcca ggcagaaggt tttgccgctg gcgaattgaa acatggaacg attgctttga
    49081 tcgaagaagg aacaccagtg attggaatca tcagtgaaga agtgactggt gcgcatactc
    49141 gaggaaacct gaaagaagtc gaaagccgtg gcgctaaaac actagttatt gtctcagagg
    49201 gattagaaaa ggaaagtgac cagctggtgc taccaactgt ccacccttat ctaactactc
    49261 taaccacagt cgtaccgact caattacttg catattacgc aacgctatta cggggattcg
    49321 acgttgacaa accacgtaat ttagcgaaat cagtgacagt agaataataa aagaacaagg
    49381 accagtgtca gacatctgac actggtcctt gttcttttat tttttatgaa aatatctctt
    49441 aatccagtcc gatttcttct ttgactactg ccgcgatttt atcgacatag taattaactt
    49501 tctcatcagt aggcgcttct gccatcactc gaagtaatgg ttctgtaccg gaaggacgaa
    49561 ctaggattct tccttctgat cccatttcag cttctgcctc ttcaatcact tttttgattg
    49621 ccggaacatc catcgcaccg tttttatcac ttactcggat attcactaat ttttgcggat
    49681 agattgttac ctctgctgca agctctgata atttcttacc tgtctgtttc atgatattca
    49741 gtaactgaat tcctgaaagc atcccatctc cagttgtgtt aaaatctaag aaaatcatgt
    49801 gcccagactg ctcgccgcca aagttataat cgtttttgcg catttcttct acaacgtaac
    49861 gatcaccaac ttgtgtaacg acatctttca aaccgattcc ttccaccgct ttgtggaatc
    49921 ctaagttact catgacagtc gtaacgatcg tatctttttt caatcgattt ttttctgcca
    49981 agtatttagc acagataaac atgattttat caccgtcgac aatgtttcca agttcatcca
    50041 ccgcaataat acgatcgcca tcgccatcga aagctagtcc agcatctgct cctttttcaa
    50101 cgaccatctc agctaaacgt tctggatggg tagagcctac gccatcattg atatttaacc
    50161 cgtctggatt tgtgcccatg gtataaaaat ctgtttcaag atcggcaaac aaacgattaa
    50221 cacttgttga agttgctccg tttgctgcat cgacacaaat ggtcaaaccg gaaaggtcac
    50281 cgttgatcgt ttgtacaagg aattgagaat atttcaataa gccttctgga aattcttcta
    50341 cagttcccaa tccttcagct gatggacgag gcaattcatc cacttcagca tctaataatg
    50401 cttcaatttc tagctcttgg tcatctacta gtttaaaacc atctgcaccg aaaaatttga
    50461 ttccattatc ttgtgctgga ttatgagaag cagaaatcat gacccctgcg cttgcttttt
    50521 gcaaacgtgt cagataagca acacctggtg tagagatcac acctagctgg aacacttcga
    50581 tacccaccga taaaagtcct gaaatcagcg cttcttctaa catttgacct gagattcttg
    50641 tatcccgccc tactaacacg cgtgggcgtt ttccttcttc ttcatgctgg cttaggacat
    50701 aacctccgca ccgtcccagc ttaaatgcaa gttctggcgt aagttccttg ttggcttcac
    50761 cgcgtacgcc gtctgttcca aaatatttac ccatagttgt aaaattactc ctttaactta
    50821 attttctgag gaatttgttc tgctcatttg tgttgattcg cttgtttctg atgtttcttc
    50881 tgtacttgtg gtcgagctgc ttgtcccaga ttccgaactg gaagaaatgg ttgttgtcga
    50941 tggttccgtt cctgaatcag cagatgaaat acttctactc gtacttgtat tttcttgtgt
    51001 ccgactgctc gtcgaagcag agctactgct tgacgtttgc aacacgggtg taatctccac
    51061 actaactgat tcgggcttga tacttaaccc ctcttctact ggtatttcaa ttttacgagt
    51121 tgttcgatga ttgatacctg agacattgat cggtacagca atactgtcac cgatcgatgc
    51181 aagcaaatcg ctagagccgc ttacttctgc ttccagtttt gaaaaactga aatcatagct
    51241 ttctaccccg gcagctggtg ttccttgctg tatcccataa agtcgtaccg acttgcttgg
    51301 cttgatcgaa tcagctctca ctgttacttg cactggatca gagacgatac ttaatacttc
    51361 ccctgctgca ttcagcgcct gtattgggac ctcactatta atcccatcat ctgtgaccat
    51421 cgaagcgtcc acatcagcta ctactcgttt gatttctgcc aatgttttgt cacctgtagt
    51481 gatagagact tttttaggac taacggaagt atcatcaagt tcatatccag atggtgtgaa
    51541 cgttgaagga atcaacgttt ccacatcgaa atcttttatt acctttttct caaccgttac
    51601 tgtaatagtc gatggttcga tctttgctgt gacagcactg ctcaaatttt gaatttttag
    51661 cggaacctca tgtgttcctt cgcccagctt agtgatatct gctgtgacgc ggaacatccg
    51721 tgtatcttcg tttgcctctg cattcaactg aactcggttt gcactggaaa gtttgacagt
    51781 cactgcattt tcatatccat ggatatagta gcgctttgaa tcataagaaa tcttgattgg
    51841 caccccagta actgtttgat tatacgcttc atttccagaa agcgtatttg gaacggactg
    51901 gccatttgca ttgaagtaca gcgcaatact gaacagcaat gcaataaaac tgtaaagaat
    51961 gcttgtccgt ttctcttttg agatcatttg cgatcccctc ccttagtcat accgtctagg
    52021 aaagattgaa tcacgttttt cttgtttttt gttttctctt cagcaatcag ttctctacgc
    52081 aaaattgcca aatattcttg ctgggataag ccagccatca gttcattatc taatgtaatg
    52141 ctgacatccc cagtttcttc agagacaacg atggtaatcg cgtcgctgac ttcgcttata
    52201 ccgacagctg cccggtgtcg agtcccgaat tcttttggaa tcaacatact ttctgataga
    52261 ggaagatagg cgcttgctac tgcgatcttt ccttctttta caataactgc accgtcatgc
    52321 agcggtgtat taggaataaa gatattgatc agcagctctc cagtgatatc tgcatctaat
    52381 gcaattcctg tctcaatata ctcatctaat ccagtatgcc gttcgatagt aattagcgca
    52441 ccgatttttc gcttggacat atattggatg gctttgtcaa aagacaagat catcttctca
    52501 tcttcctgct gttcgctttt tgattgtttg aaaagcgaac tgcgtccaag atgttccagt
    52561 cctctccgga tttccggctg aaaaatcacg atagcagcta tcaccccgta cgtaatgact
    52621 tggttcatca gccaagacaa ggtgtgcaga ccaatgattt ccgctacgat tcggataaca
    52681 ataaaaatag ctacaccttt cagaagctga atcgcttttg tgcctcgcag cagttggatc
    52741 agtttgtata caagatacca gacaaccaga atatcaagta tgttcaccaa aaaattcaga
    52801 gagaacaagt caccggaaaa catttgctgc caatagtcca aattaaaaag ttccccgatt
    52861 tgaaatgaca taaaaagcct ctcttctctt ttgagatttc ctctctagta tatcatatgt
    52921 tttaatttta gaggctgatc tgctcgtatt tttcttgaga aaaacgcata attttcagga
    52981 aaattgcaag tatgcgtttt atttttctct gcaataaata tttttaaact tcagagaatt
    53041 attcattata ttttttctgt tatttttcct ttttttcttt tgtagcttgt tccatttttt
    53101 tacgtcgttc tgctctggca gctcttcttt cttctgcttc aaggtccgtc gttttttctt
    53161 ttctagtctt aacgggtaca tcgatagatt cctctggttc aagtcgtttc ttgatttttt
    53221 ctaattctcc cgtcagtgca gcatagttgt aaaaacgtgt tttagcgtct tggatagtct
    53281 tttcaaataa agcttttgca agatttggat ttgcgttctc tagcgaggaa aagcgaactt
    53341 gtttcctcat gaaatcaggc atagcagaga aatcaggttt tttgtagtcc aaagtcattg
    53401 ggttcttgtt tttttcgacc attgcagggt tatatcgata taatgaccaa tagccagaag
    53461 aaacagcttc ttttgcttct ttaagcgatt ctttcattcc accaagcaaa ccatgtgtga
    53521 tacaaggcgt ataggcaatg attaaagaag gtccaggata cttttctgct tcttcaaaag
    53581 cctttatcgt ctgcatttga ttggcacctg aagcaatttg cgccacataa acatttccat
    53641 atgtcatcgc catcattcct agatctttct ttgaagcata ctttccacta gccgaaaatt
    53701 tagcgattgc cgaagctggt gttgcttttg aggtttgacc gccagtattg gaatagactt
    53761 cgttatccaa aacaagaata ttcacgtctg ctccgctggc aagtacatga tcgatcccgc
    53821 caaaaccaat gtcgtaagcc catccgtctc caccaatcat ccattggctg ttttttacga
    53881 atagatcctt tctcttgtat atatcctcca gttcagggac aattgatcgt tcgctttcga
    53941 tcgcagcttg cagttttgct gctctttgct gcgttccttc gctctcaaac atgtgtacca
    54001 accagtcttc catcaattct cgtagttctt ctgatacttt tggcaatact tctttgattg
    54061 aacttgccaa agcctcgcga cgagtctgtg ccgctagaag cataccataa ccaaattcag
    54121 cattatcttc caataaagaa tttgaccatg caggcccttg accacattca ttggtcgtat
    54181 aaggagaagc aggagaagca ccgccccaaa tagaagaaca gcctgtcgca ttcgcgatca
    54241 tcattcgatc accgaacatt tgtgtcaata attttacata aggtgtttcg ccacagcctg
    54301 agcaagcgcc cgagaattca agaagcggtt gattgaattg tgtagacaag acagtattct
    54361 ttcctttgac tggatttgct ttttgtctta atgtcattgc aaaagcccaa ttcacagctt
    54421 gttctttctg ttcttcataa ggcttcatca ctaaagcttt ttcttttgcg ggacaagcct
    54481 ctacacacag accacaacct gtacagtctt ccactgaaac ttggatacgg tattttacgc
    54541 cgtctgcgcc tcgcatttct ctcacgataa atccttctgg cgcttcttcc atttcctctt
    54601 catctgctaa aaatggacgg atggcagcat gaggacaaac aaaggcacat tcattacaca
    54661 tcgtacagcg atcactaatc cactcaggta cttctaaagc gacgccccgc ttttccatag
    54721 aagccgttcc taaaggcatt tcgccagttg tcattccatt tgctacaagt gtaccaacag
    54781 agagttgatt tccttcctgt gcattcactg gttcaagtat ttcttgtata taaccagtgt
    54841 tccttttatt gattttttca ggcatctcca acgttctcca atggtctggg atcgcgactt
    54901 gatgaagcag ttcggtcgtc cgatcgattg cttgtatgtt tttttctacg atagccattg
    54961 atttatgtcc atagcttttc agggcttctt cttttagcag cggaagcacc tcatcaaaag
    55021 gaatgatgtc agctaattta aaaaaagccg tttccattgc cgtattgatc cggcgtccca
    55081 aaccgacttc ttgggccaat ctcatggcat tgatcgtata gaatctaatg ttattttcag
    55141 ccaagtaacg ttttaatttt aagggcagat gcgtttctaa ttgttcgtcg ctccaaagag
    55201 tattcaataa aaaaatgcca cctggcttca atcctttgac caagtcatag ctatgcaggt
    55261 aagctggtgt gtgacaggca acaaggtccg catgctcgac aagatacgct gaacgtatcg
    55321 gcgtatctcc aaaacgaaga tgagagacag tcagaccgcc agattttttc gaatcataat
    55381 aaaaatagcc ttgcgcatat ttatcggtgt gatctccaat aatcttgata gctgatttat
    55441 ttgctccaac tgttccgtca gatccaaatc cccaaaactt ggcctggaat gtttgcggtt
    55501 ctgtcaaatc cagactttcc tttggttcca aagattgata agtcacatca tccacgatcc
    55561 ctatggtaaa ccgttttttg cgtatgcttg ggtctttttt caattcatca aaaactgctg
    55621 agatttggtc gggagtcaca tctttagacc ccaatccgta gcgaccacca ataacagccg
    55681 ggcgaagttc agaatcatat aacgcacttt gaacgtctaa taagagaggt tctccacctg
    55741 cccctggttc tttacttcga tcaagaacag caattgtttt tactgtatga ggcaactttt
    55801 gcacgaatgt ttccactgga aaaggacgat aaagatggat attcaaaaaa cctgttttcc
    55861 gtccgtttgc attcaagtaa tcaatcgttt gttcaatcgt ctgtgcaact gatcccatag
    55921 aaacaatgac ttcttccgca tcgtctgctc cgtaataagt caccaagtca taagaagttc
    55981 ctcgtaatcg gttgatctct ttcatatatt tttgaacgat ttcaggtaat ttatcataat
    56041 aggggttgat cgtttcccgt tgttgaaaat ggatgtctgg attctggttc gtaccactaa
    56101 cagtcggatg attgggattc atccctcgtt tacgaaatga agctaatttc tcctgattga
    56161 tcagaggagc taattcttca tattccaaaa cttcgatttt ttgaatctcg tgactcgtac
    56221 ggaatccatc aaagaaattc aaaaaaggta cttctccttc aatagaagca agatgggcaa
    56281 caggtgctaa atccatcact tcttgtacac tgctttcagc taacatagca aatcctgttt
    56341 gtcttgcagc catcacgtct ccgtgatctc cgaaaatatt caacgcattt gtcgtcactg
    56401 cccgactagc aacatggaaa acacttggca gtagttcccc agcaatcttg tacatattcg
    56461 gtatcatcaa aagcagccct tgagaagcgg tatatgtagt tgtcagtgca ccagttttca
    56521 atgatccatg gaccacacca gctgctcctg cttcggattg catttctact acttttactg
    56581 gttgaccgaa tacattttct tttcctgctg ctgaccattg atctactaat tcagccatgg
    56641 tcgaactggg tgttattgga tatattgcag caatctcggt aaatgcataa gaaatatatg
    56701 cggctgccgt attgccatcc attgttttca tttttcgcat gattcatcat ccttgttcat
    56761 attctctctt attatctgtt ccattataac gtaaaacatt ccattttttc ttttatttat
    56821 aaaaatattt cacatatgtc tatttgaatt ggtcatctaa tttttagaca aacagtctaa
    56881 atcgttgcct ttttttgtca gacatgtata aactataagc gaaagaggtg ttttaacatg
    56941 gatatatcag tgattgatgc aacgaaaaca aatacacaaa aaggaatcct ttatggttca
    57001 tcgaatgctc ctaaaaaaat ggtcgaattc atcaacctat cttgtccgta ttgccgacaa
    57061 tggtttgaag aatcttatga gctattagaa gaagcagtcc aaagcgggca attgcagcga
    57121 gtgatcaaat tgttcgataa agaaaaagaa agcttgcagc gaggaaacgt gatgcaccgg
    57181 tatctcacaa tcagcgatgg tcaaaaagcg atcaaagaga tcaaacaaat attcgatact
    57241 caagacgagt ggaaacatct ttctctccaa gaagtagcgg attttgcagt agataaacta
    57301 aagctgacag aacaaaaaga cgaacagctg agccaagctg tcatcaacga agctgagcaa
    57361 gcacatattc gatttgttcc gactgtcatc ttgggtaaag aaatctttga tgaatctatt
    57421 tcaatagagg aattaaaaga attgatccaa acaaaataaa aaaataagga gcgtaggaca
    57481 aaagtaaaga acacttttgt ctcacgctct aaacacctat aaacggcgga agcagaagca
    57541 actccttctt atttcttgga gttaaacgct tctgtcccag cctccttatt ccgaataaat
    57601 ggtgtccaaa agcttgcatc tgccagatta tctcatttct tatgacaagc tgagcaaatt
    57661 atctccacca aataatttat tcatattttt gacttgcgca tactaactaa ttcttaaatt
    57721 ttcatacaaa atttctcaaa ttcccttaac gagtaatatt tatgtacggt gattcacact
    57781 agtatcccaa tcacttttta agttatcccg atttcaattc tacttcaaaa atagttgctt
    57841 ttatgtatgc tgttagttga ttagatggtc gtttgttgag ctaggtcgtt tattttaaac
    57901 aagttgtttc tttagcttat acctatctcg tctaccaaac gcaagatggc aaacacaaat
    57961 gcatacgcat ctgtatttgc cactttgatt cgtataaagc taacaactcc taactcctct
    58021 catttaatag ttgctctctt ttttattcag atacattttt gctgatcaca gcctagtatt
    58081 tcaatggttt tgaacactaa accaaattgt tccattacaa cattcactgg ctgatgaaat
    58141 ggattaatag atttcgatta ttcaaagcga ttttctattg gtggattgtg ttcccaacta
    58201 acaagacgga ttccaaagtc attatataac tcttcaagag ttaacccttt cctgttccca
    58261 atagatgtat ctctcccacg ctcgatataa aatatggagt ttcgaatgcc aagacctggc
    58321 aaatctttcc ttgttacagt tacactgcta ctaacttccc catataaaat ccagctcctc
    58381 caaaatgata atatattttt cgaccatcat ctaactcatg taacaataat tgttgtgccc
    58441 tcttgtcact cgccaaatgc aaacgccacg tgcgatacca tgccatgcta cctgcatctg
    58501 cagaaaatcc atcaaataat gcaacaattg tatcttctat cacaatcctt tccccatcta
    58561 cttcatattc taatctaaaa tcaaactccc ctcgggtaat cgcaggtctt ggtggcttag
    58621 gacccaatat tattctactt aaaaccgcat tcgttcccag atgaaacaca gctataacaa
    58681 caataatgat taatattttg tttctatttg ataaatttct cattattcgc aaatcacctc
    58741 tacattctca catactagtt cgtaatactc ctttaatatc aaaatatcta ctgatcgtaa
    58801 taatattcgc tatgaattcc tactactcgt ataagaaagg ccaaatcatc agcttttact
    58861 tgctgatgat ttggcttgtt tctatttatc gtaattgttt tctaatcacc aaaattgtta
    58921 acaatcggtt cagatatttc ccaattcact agccttatat tatattgatt taacaattct
    58981 tcttcattta ttgtattttg atcaagcgga ccaaattgtt ctaataattc tttgtcatgt
    59041 aaaatatccc ttctagtaat gcctctttcc ctttcaatga aagaagcact aggaaaagta
    59101 tgattataac cattcaacct atctcccatg taataattag caggtcctgg aaaataaaat
    59161 atttgcttat tatcactaac ttctaacagc aacactaaat cttctccgct ggctaaacga
    59221 cttgtccatc tacgatatct ccctatgcct tcgttcattc caaatccatc aaattcaact
    59281 attaacgtgt cttctatcac atgtaattct tcattcaatt catactcaag tctaaaagga
    59341 aattctccat atgtaatctc tggcaatggt ggtgctggag ttctccaaat aaatacaata
    59401 actgtgaata gaaaaaatcc aacgatcgat ataaatgtta tgagacctgc tcgaagtaaa
    59461 acccgatata ataaaaatgc tgtatttcgc tttgctatat ctagaaaaat aaaaagtact
    59521 gcaatcataa tgatagtaaa agttgtaaaa aaacgcattt ttgccctccc tttataaaca
    59581 tcgattctca aattctaaac caaatcttgg tagttcaagt tcaggtataa cgtattccaa
    59641 ccatacatct caattactat ttatgaactt atgattatca ctgaataaat cactccatcc
    59701 ccttgttaaa acttctacat taattacacc tggttgtttt cgactagcta atccaatgaa
    59761 cttatcaacc atccttatcc accaaccacg agaatcttga ccagaagtaa gaagagcagt
    59821 tctcaaggat gatcgagcag ttccttccag ttttttaatt aatcaggcca gttatagata
    59881 aatacttgat cttatctata tcaggacttc tatattaagc aaaaatttat gtacaaaact
    59941 aaaatcttca ttcagttgtc tccccgcttt ttatacgatt gtattaaaaa caatagaagc
    60001 ctttccaaat tatgttactc cagtaaagat ggaattatag tttgacggaa gaaaagcaag
    60061 tataactttt aaaaaaaact gatacattcg catctcctgc ttcatgtatc agttttttct
    60121 ttggattaaa ctgcttcttc acgcagtttt tccgcaaatt catttatttt gcgaattcgg
    60181 tgattaattc ccgattttga tatcgcacct gagggaatca tttcccctaa ttctttcaag
    60241 ctgacctctg gatgttgaag ccgaagttct gcgatttcct gaagtttttc aggaagggca
    60301 tgtagaccga cctttgcttc gatcaattcg atgttttcga tttgtttaga agccgcatca
    60361 atcgtcttgt tcagatttgc tgtctcacaa ttgactagac gattgaccga atttctcata
    60421 tcccgtacga ttcgaacatc ttcaaatcgg agcattgagt tggttgcacc aatcaatgtt
    60481 aagaaatcag caattttttc tgctcctttt aaataagaaa tatagccatt gcgccgttca
    60541 agcgttcgag catgtagacc gtaataattt aacatatcgc aaatgtcttg gttatgctgt
    60601 tcataaatag aaaatatttc caaatgataa cggctcgttt ccggattatt gactgaacct
    60661 gaggccataa aagcaccacg taagtaagaa cgcatttttt gcgaatttcc cataatctcg
    60721 tccgaaacgt gtccattgaa catcatacca tccatgatat caagatccat caacacatct
    60781 tttgtgcctt gcttcaaccg gacgatatag acattgttct tttttaattt cattttttta
    60841 cgaacgagta gctcacttcg tacctgataa tgatctttca aaagagaata gatacgtctg
    60901 gcaattgcag cattttctgt ttggacgttc aaaataaact gctggttcac aatacctaaa
    60961 gagccgttca ttcgcagcaa agcagctaat tccgctttcg catgttctcg atgaacttcc
    61021 aaaccagtta gttctttctt cacatctgca gcaaatgaca tcctattctc ctcctttctc
    61081 caacaataaa ttgcttaata ttttgaaccg aaaactaaac ggaacaattc ttctactact
    61141 ttgtctccat cgtggaagac accaccatct ttcaattcca aaaagtcggt ggaaatcact
    61201 cgacatcctt catttctcaa tccgttgaag tcgtgtgcga cttgtactag atactcatca
    61261 tagatctctg ggtccatata atcttcaggc actttttccg tattgaccaa tactgtatcg
    61321 ataaaaggct gattcaaatg cttgtgtaaa acacgtatat gatcggcatc tgtgaaatgt
    61381 tccgtttccc ctttttgggt catgatatta cagatataga cggtttcagc agttgtcttg
    61441 agcattgctt cgccgatttc tggtatcact aaatttggaa ggatactggt gaataaactt
    61501 ccgggtccca aaacgaccat gtcggcgtcc ataattgctg aaacgacttt tcgagccgct
    61561 ttggcttcac ttttatcatt tgtgttgcag acatacacac ggtcaatggt tttacggtcg
    61621 atcgcgattt tagattctcc tactgcagtc gttccgtctt taaagacagc atgcaaggtc
    61681 aaaggagttt ctgaagaagg ataaacatgt ccatctacat gcatcatttt tgctaataat
    61741 tgaatcgcct cataagtgct tccccgcatc tcggaaactg cggcaatgat cagattaccg
    61801 atcgtatgat tggctaaaaa ctgatcttcc tttttgaaac ggtattggaa aatatcttca
    61861 tagaattgtg gcatatccga taacgccact aagacatttc tcaagtcacc aggaggagcc
    61921 atagcgatcg attctctgat tgcaccgctg cttcccccat catctgcaac agtcactact
    61981 gctgtgatat ctgctccttg atttcgcaaa cttttcagga taactggcag accagtgcca
    62041 ccgccgacca ctacgatctt tggttttctt atccggtagg ttttcatttt cacgaccggt
    62101 tcaccgtctc tttcctttta tccttgtccc gatgtgtcac attgacttta tagtttttcc
    62161 ctaaagcatt tgccaaacgt tcagtcaatg ccacagaacg gtgttgaccg cctgtacagc
    62221 cgattgcaac tgtcaagctg ctttttcctt ctttaatgta tccaggcaat acagtttcca
    62281 gaagatccaa aaatttatgg tagaatgatt gcgtttcatc aaaggacatc acataatcat
    62341 agactggctg atcttttccg gtcaatggtc ttagttccgg gatataatga gggttgggca
    62401 aaaaacgcac atccatcaca atatccgaat cgatcggcaa cccgtattta aaaccaaatg
    62461 atacaaattc gatccgaaat ccttggtctc cctttgattt gaatgactca ttgatttttt
    62521 cacgtaattg tcgtggtgtc aatgtcgtcg tatcaatgat cacggaagct tgggctttca
    62581 agtcgtctag tatcgcccgt tctttacgta tcccttcagt gatcaaaccg tccatcgcca
    62641 ttggatgtgc tcgtcttgtt tctttgtagc gagccactag ttcttcgtct gaagcatcta
    62701 aaaataagat agaagtgtcg atgaagttcg tattttcgat ttcgatcagc atgttttgga
    62761 tttcttcaaa gaaggaacga gaacgtaaat ccactcctaa agccattttt gtgactttgc
    62821 ctgattcttt gattaattcc cagaattttg gaatcaatcg aggcggcata ttatcgatac
    62881 aaaaatagcc catatcttca aaactttgga tagctactgt tttccctgca ccgctcatac
    62941 ctgttatgat gactaattgc aaattatctg tcataattac gaactcctct cacattgtgc
    63001 atagtaaaat tatatcattc cgggcgtatc attaccagtt ttctttttct tttacaaaaa
    63061 gatttggacc aaatatcttt taggatattt gccccaaatc caattttttt acttttccga
    63121 tgctgtatcc aatgccttgc ttctttcagc tagcgctcgt tcaatcgtcc gatctgctaa
    63181 aatagattgg gcatcgatca ctggataatg gttatcttca gcaaattcat gcatcaatga
    63241 caattctgtg caacctaaga taactttttc acagtttagg cgctctaccg cttcttctaa
    63301 gatttcgtaa tatagctctt gattcaaata atccgattcc ttgatctcat gatagatcag
    63361 ataattgatt ttttcttgaa gaacagtatc aggaatcact gtttcgaatc caagattttt
    63421 gacttcgcgt tcatagattc cagctttcat acttccttct gttcctagaa tcgctactct
    63481 ccctgtcgta tgctgacgga caagttcatt tgctgcttct cttggcatat gaaggatagg
    63541 aatatccgtt gccgcttgta attcttcaaa aaagtagtgt gcggtgttac aagtcaacac
    63601 aatgaagttc ggctgcaata aattttgttt ctcaatatca tccagcagaa acggcattgg
    63661 attttcttct gatcgatcta aaatataagc tgtacgatca ggaactgttg catgattgaa
    63721 taagacataa ttcaaatatt cttgatcttt tgtagctttc gttcggtggt tgatcaagcg
    63781 aacaaaactt tctgtcgcca tcgtgcccat tccgcctaaa atactgaaaa aattctccat
    63841 gaactagcct tctttcacat gaaaatactt tttgaatctt ggaatatagt tatggaacat
    63901 atatttcatc aacaaccagc gcttgattga ccggtctttt tcataaaaca cagtagtacc
    63961 gtaacgattt tctttgatca tttgctcagc tagttttttg tcttcatttt cccgagcata
    64021 ttctaaaaag atttttttgg gcacacccat ccataatctt gctttatctg attgattcgt
    64081 tccataggtc gtttcaacaa agggtttgtt aaacactcga tcttctgtga cgaaacgagc
    64141 cagattcaag ccgttcaatg tcacaaagaa actgctacga ccttgtctca aattgatttc
    64201 aaataattta tattctccat ctctaggatc atacttcata tcgaaattgg caaagcctgt
    64261 atattcgatt ttttccaaaa atgccttaat ggtttgatag attttttcgt tataatctgg
    64321 catgatcaca acgtaattac caatcgatgc tggtgtagga tcttctaaca gtggatgacc
    64381 aagacacatc atccgaactt gatgatcttc atctacatac gcatttagca cacgcatatt
    64441 actatcatca cccgggataa aatcttgtac aatcatttca cttttataac cggcttcgta
    64501 tatccggcct aaaattaaat cgaactcttc tctagtctct aaaataaaag ctttttttct
    64561 tccttcaaat tggacagaaa gatactccac actgtttgca ggtttcaaag caactgggaa
    64621 ttcaaaaggc aattcctgtt ccaaatgtcc atttactaac atttcttctc tgacgatcaa
    64681 tgttttagga tacggaagat catattcttc acaaacttca taaaagctta ctttattgat
    64741 cagtctttca aataaagaat aatcaatata tggacagata aaatattctg acagctcttg
    64801 tttatgttgg gagatcaatt ctgcatatcc atcaccacaa gcaatcaaaa gatatttttt
    64861 actcttatca gaatatcttt cttttgccaa acgaagcatc gtctcgataa acacagggtc
    64921 tttatcaaat cctggaataa cttctacatt gacaatttta ctgtagcggg taggggctaa
    64981 ctgatccgaa gcatatgctt ggcagatttt gccgtatgct tcattaaaag aacgtgccat
    65041 accataaacg ttcatgtcgc ttcctaataa tatagggata aattcttcat tttcaatact
    65101 gttcatcatt atctctcact tactcataat ctcttgtttt tcttttccaa ctacacaagg
    65161 aatatcatac cataaagaaa aaagcaatca aaggaaactc ctccgattgc tcaattcttt
    65221 tttgaacgga ttgaacttat aggaagtttt tgtctatacc aatcagtgta gaaagaacta
    65281 ccatgtaatg attctagaac actgatatta ataaaacaag caaaaattca tttttttatg
    65341 tttttttaac tatctcagct atctatcctc tttataccat tatttttttc aaatagtgac
    65401 ctgtataact ttcttttacg ttaatgattt cttctggtgt tccagtcgca aggatcgttc
    65461 ctccaccttc tccaccttct ggtcctaaat caatgatata atctgctgtt ttgattacat
    65521 ctagattgtg ttcaatcact aaaactgtgt taccagcatc tactaatctt tgtaatacat
    65581 gcaacaagcg ggcgatgtca tcgctatgaa gtcctgtcgt tggttcatct agtatataga
    65641 aattctttcc attagagatt ttgtgcaatt cactggcaag tttcatccgt tgtgcctcac
    65701 caccggacaa tgtcgttgct ggttgcccca tcgtcacata acctaagcca acatcaacaa
    65761 tcgtttgcag tttgcgatga atctttggaa tgtgcttgaa gaattctaca gcatcttcta
    65821 ctgtcatttc caaaatatca gcaatgcttt ttcctttgta atgcacttct aatgtttcag
    65881 agttatatcg tttgccatga catacttcac aaggaacata gacatcaggc aaaaagtgca
    65941 tttcgatctt aataattcca tccccgcgac aagcttcaca acgaccgcct tttacgttga
    66001 aactaaaacg ccctttctta taaccccgca tttttgcctc gttcgtttga gcaaataacc
    66061 cacggatatc atcaaataca cttgtataag tcgctggatt acttctcggc gtccggccga
    66121 ttgggctttg atcgatatcg atgatctttt cgatactttc gtagccggaa attgtcttga
    66181 atttacctgg cttagcagaa ttcttattta atttttgcgc taacgatttc tttaagatac
    66241 tattgaccaa tgtactcttt ccagaaccag acacacctgt gactgctaca aattctccta
    66301 atggaaattc aacactaata tttttcagat tgttttctga agcaccagtg atcttgattg
    66361 ctttcccatt acctttacgg cgttcttttg gtacagggat tgattttttc cctgaaagat
    66421 atttccctgt caaagaattt tcatcattag ctacttcttc aggagtgcct gcagccacga
    66481 tttgtccgcc ttgttctccg gccccaggtc cgacgtcaat cagataatct gctgcccaca
    66541 tcgtatcttc atcatgttcg actacaacga gggtgttgcc aagatcacgc attttcttta
    66601 atgagccaat cagtcgatcg ttgtcgcgtt gatgcaatcc gatcgatggt tcatctaaaa
    66661 tatacaaaac tccagaaaga ttcgatccaa tttgtgtagc caatctgatt cgctgcgctt
    66721 ctcccccaga taatgttccg gaagcgcgac tcaaagttag atagtctagt cccacatttt
    66781 ccaagaatga aagtctgtca tttacttctt ttaaaatcgg tttggcaatt actttctctt
    66841 gttcagataa cgttaagttt gagaagaaat ctactgcttt ttgaatagac aactcatttg
    66901 tttgcccgat attcgttcca ttgatttgaa cagatagagc ttggggattc aatcgataac
    66961 ctttacatgt ctgacaagtt aattctgtca tataaagacg catttgctca cgcgtgaaat
    67021 cactgttcgt atcatgataa cgacgctcga tattcttcaa taccccttcg aaagtcgttt
    67081 ctacatcgcg aacgccacca aaatcatttt cataatggaa atggaaaaga tcatctgtcc
    67141 cattcaagat gatatcctga tgctcttccg gtaattcttc gaatggtgta tctaaatcga
    67201 taccgaaact ttcacaagcc tgcgctaaca tttgaggata atactgagag ctgattggat
    67261 tccatggaac gatagcacct tgactaagtg tcttcgttct atctggaatc actaaatctt
    67321 gatcgacttc taatttgaca cctaaaccat cacagtctgg acaagctcca aaaggcgcat
    67381 tgaatgagaa cagtcttggt tctagttcgc caacagtaaa tccgcaataa ggacaggcat
    67441 agtgttcgct aaacaacatt tcttcttcac cgatcacgtc aaccagagca tagccgtctg
    67501 ccaatcgcag agccgcctct aaagaatcaa atagacgaga acgaatccct tctttcacaa
    67561 tgatccggtc gatgacgatc gcgatatcat gttttttgtt tttctccagc tcaggcactt
    67621 cacttaaatc atagatctca ccatcgactc gaacgcggac gtatccctct ttttggattc
    67681 gttcgaatat ttttttatgt tgtccttttt tctttaccac gatcggtgcc aacacttgga
    67741 tctttgtgcg ctcaggcaaa gccattactt gatctgccat ttgatctact gattgactgg
    67801 taatctcgat atgatcgttg ggacaaatcg gatgtcctac acgtgcaaac aacaagcgta
    67861 aatagtcatt gatttccgtc acagtaccta ctgtcgaccg aggattttta cttgttgttt
    67921 tctgatcaat agaaatcgcc ggactcaatc cgtcgatgct atctacgtcc ggcttatcca
    67981 tttgtcctaa aaactgacga gcataagcag aaaggctctc tacgtatctc cgctgccctt
    68041 cagcgtacag cgtatcaaat gctagggaac tttttccaga accggacaaa cctgtaacga
    68101 ccacgaattt atctcgtgga atcgttacat ctatattttt caagttatgg gcacgtgcac
    68161 cgtgaatcgt aattttatcg ttagccatgt tgtcctccta ctttgaagct tttaattcta
    68221 aaatcatatc tcgcacatta gcggctgttt caaaatccaa tgctttcgcc gcatttttca
    68281 tttctttttc taatttcatc aataacgtat ctttttcttc tttcgtcatt tcttcatacg
    68341 agacttgtac cgcttctttt gtatcatctt ccgattcttt cgtaatagaa atcaaatctc
    68401 ggatttcttt aatgatcgtt tttggaacga tcccatgttc ttcattgtac ttctgctgaa
    68461 tcgtacggcg tcttgatgtt tcatccatcg ctagacgcat agaatctgtt actttgtctg
    68521 cgtacatgat tactttacct tcttcattcc gagcagctcg tccaatcgtt tggactaagg
    68581 aacgttcact acgtaaaaag ccttctttat ccgcatccaa gatagcaaca agggaaactt
    68641 caggtacgtc taatccttca cgaagcaaat tgattccaac taacacatca aattcaccta
    68701 atcgaagatc tcgaatgatt tctgttcgtt ccagcgtttt gatatcacta tgcaaatatt
    68761 tgactttgat ccctaattct ttgaaataat ctgtgaggtc ttctgccatt tttttcgtca
    68821 atgtcgttac aaacacccgc tggtcttttt cgactcgttc atttatttcg cctactagat
    68881 catcgatttg tcccatgatt ggacgaactt cgatcactgg gtcaagcagc cctgtcggac
    68941 ggatgatttg ttggataacg gtatctgttt gttcatgttc atatggtcct ggcgtcgcag
    69001 agacataaat gatctgattg acatgttttt caaactcttc taaccgaagt ggccgattgt
    69061 ctaaagcaga tggcaaacgg aaaccgtaat ctactagcat ctgttttctc gctcggtcac
    69121 cattatacat tcctctgact tgaggcatgg ttacgtgcga ttcgtccgcc acgatcaaaa
    69181 aatcttcagg aaagaaatcc aatagcgtat aaggcggttc accttcttta cgtccgtcca
    69241 tatgccgaga ataattttca attcccgacg tgtagcccat ttctaacatc atttcaatat
    69301 cgtaattggt tcgctgttct aaacgttgag cttccagaag tttgttttca tttcgcaaga
    69361 cagttaaacg ctgttctaat tccgctttga tattcgctac ggcatgctcc atatgttcat
    69421 cattcgtcac aaagtgagtc gccgggaaga ttgccacgtg ttccgtttct cctaaaactt
    69481 cacctgtcag tgcattgact tctcggatac gttcgacctc atctccaaaa aactccacac
    69541 gtaaggcacg ttcatctctt gaagccggaa aaatctccac gacatcaccg cgcactcgaa
    69601 aacgaccgcg ctgaaaatct atatcatttc tttcgaattg gatactgact aagtcacgaa
    69661 tcaactgatt gcgatctagt tctgctccct gtcgaatcga aactacttgt ttttggtact
    69721 caaaaggcga acctaatcca aaaatacatg aaacggatgc aatgacgatc acatcatttc
    69781 tttctaataa tgaactagta gccgaatgtc gtaatttgtc gatctcatca tttacacttg
    69841 aatctttttc gatatacgta tcgcttgaag gcacataagc ttcaggctga taataatcat
    69901 aataagaaac aaaatattca acagcattgt tagggaaaaa ttccttgaat tccccgtaca
    69961 gctgaccagc caatgttttg ttatgggcaa taattagtgt tggtttattc actttctcaa
    70021 taagattgga aatcgtatat gttttccctg ttccagtcgc acctaataag atttgtgctt
    70081 ttttcccgcc gactacgcca tccactaatt ggttaatcgc ttcaggctga tcaccagccg
    70141 gttggtattt cgagacaagc tcaaagtgtc gggaggtatc tctctcaatc attcttcgtc
    70201 ctccttttca ttcattcctt ttcattttac gaccaataaa aagaaaagga aagcaaaggc
    70261 attccttact aaaaaattat accacaccga acatactttc gccacttttt tatcttatta
    70321 tgcatgttac gttttataac ataaaatgtt agaaactcgc atttttttca ttttttcgag
    70381 cttacagtct tgtctgattc agcacttttc gcctataata ataaaatatt ggaaatttag
    70441 gaggttgatt atgaaaagaa agcatttatt tcactcattt gttttcttaa tgacaggact
    70501 tgtgacactt gcgtttggac atgttgcaca agctgacaac actacaacgg cagagtcaag
    70561 cacaagcgag acaatgcaaa aaatagagcc caaaaaagac gtatacgtaa ttgccagtga
    70621 ctctgctttt gctccatttg aatttcaaaa cgcaaagggc gagtacgaag gcatcgatgt
    70681 aaaattgatg gaaaacatcg ccaaactgca aggatttaac atccgaatgg actaccgtgg
    70741 tttctctgct gctttgcaag ctttggaatc aggacaagca gacggaatga ttgccggaat
    70801 gactgtaaca gatgaacgaa agaaaagcta tgatttttct gattcttact ttgatagcgg
    70861 gatccaatta gctgtcaaaa aaggagatac ttcgatcaag tcttatgaag atttgaaagg
    70921 aaaaacagtc ggagcaaaag ttggtaccga aagtgctgaa tttttaagcg accatgaatc
    70981 tgaatatggc tattctatca aatattttga tgctgctgat caattgtacg acgggttaaa
    71041 agttggcgca atcgatgcaa tgatggatga ttatccggta atcggttatg cgatcaaaca
    71101 aggacaagaa ttggaaacac cgatcaaaaa agaatctggc ggaaaatatg catttgccgt
    71161 taaaaaagga caaaatcctg agcttcttaa tatgttcaat gaaggattga aagaattaaa
    71221 aagaacaggc gaatacgata agattattaa agaatatgta gcggatggtt cagaaacttc
    71281 cagtgagtct tccactgctg atgaatcaac atttcttgga cttatccaaa acaactatca
    71341 agcattgttg aaaggacttt ggagaacaat tctcctaact ttgatctcct ttgctttggc
    71401 tatagtaatc ggtgtgattt ttggattatt cagtgtagca ccaatacgcg ctcttcgcac
    71461 aattgctagt atttatgtcg atatcatccg aggaattcca atgatggttc ttgcgttctt
    71521 tattttcttt gggttgcctg gtatcgttgg atttacgatt cctgacttcc ttgctggtgt
    71581 tatcaccttg actcttaacg caagtgctta tatcgcagag attgttcgag gcgggatcaa
    71641 cgccgttcct gtcggacaaa tggaagcttc cagaagttta ggtctttctt ataatcggac
    71701 aatgcaaaaa atcattttgc cgcaagcgat acgcatcatg atcccatcat tcgtcaatca
    71761 gttcgttatc tcattaaaag acacaacgat catttccgca atcggtgtag tcgaattgct
    71821 gcaaactggt aagatcattg ttgcacgtac aacacaaagt acgtatgttt acttgatcat
    71881 tgcgatcatg tacttgattt tgatcacagc attgacaaaa ttagcaaaag ttttagaaaa
    71941 gaaggtgaag taagatggca gaaaaaatct tagttgagca tttagtcaaa aaatacggcg
    72001 ataacacagt attaaacgac atcaatgtgt ccatcaacga aggagatgtc gtctgtatca
    72061 ttggcccttc aggttcagga aaaagtacat ttttgcgttg cttgaatcgt ttagaagaac
    72121 cttctgacgg tgaaattatt attgacggcg cccacttgat ggataaaagc acagatatca
    72181 acttggtgag acaacatatc ggaatggtat tccagcactt taacctattc cctcatcttt
    72241 ctattttgga aaacatcatt ttagcaccga tggacctgaa gaaagaatct agagaagaag
    72301 cagagaaaaa agcaatcaaa ttgctgcaga cagttggtct agaagataaa aaagatatgt
    72361 atcctgaaat gctttccggt ggacaaaagc agcgtgtggc tattgctcgt gctctagcga
    72421 tgaaccctga catcatgctt tttgatgagc ctacatctgc actcgacccc gaaatggtcg
    72481 gtgatgtctt gaacgtcatg aaaaagttag cagaacaagg tatgacgatg gttatcgtta
    72541 cgcacgaaat gggcttcgct aaagaagtgg ccaatcgtgt catgttcatt gacgacggaa
    72601 actttttaga agacggaacg cctcaacaaa tctttgaaaa tccgcaaaat gaacggacaa
    72661 aagatttctt gaataaagta ttaaatattt aataaaaacc aaaaatgccc ggtcgcttca
    72721 tgacgaccgg gcatttttag tttcttgttt tttcacttaa ctgtaccagc cgcatcgctt
    72781 gttctcctgc acaaacaagc aatcgctcta cctgttccat cgcataagaa agtaccatcg
    72841 gttcattgac gatatcaagt acatagtcga taccaccttc agaaactatg atgattatct
    72901 tattctaaag ctggcttttt tgttggtaca aacatgacaa ctacaaaaaa accaggcgaa
    72961 cgtatgattg ttcgtctggt ttttaattat taatgactta gcgtttttac tagaaataga
    73021 aaatttgggc aagtctactt tatattttta ctagaaaaac tacttccgct ttttcccgcc
    73081 aaaagcatct ttaaacttat cgaagaaacc gtcttcttgc tgttcttcaa ctttgatgcc
    73141 gccagcttca gcgaatgcac gtaatgcttc tctttgttgt tcatttagat ttttcggtgt
    73201 gatcagtttt actttgacat gttggtcgcc tgttgcacca ccacgtaact tcggagcgcc
    73261 ttttccacgt aaacggaagt tcgtacctgt ctgtgttcca gcagggatct tcaatttcac
    73321 atctccatgg acagttggta cttggacttc atcccccaaa gctgcttgta caaaacttaa
    73381 aggcaattca tagtaaattt cagaaccttc acgatcaaag atatcacttt cttctacacg
    73441 aaaaaccaca tacaaatcac caaatggtcc gccgttttct ccagcttctc cttgaccagc
    73501 taaacgcatt tgttgtcctt cttctacacc agctggtaca ttcactttaa ctgaatgtgc
    73561 tttcttctca tgtcctgagc catgacaggt tggacaaggt tctttgattt ctttccctgt
    73621 gccatgacaa acatcacaag tttgacggct catcactcgt ccaagtggcg tttggcgttc
    73681 tacattgatc gtacctgcac catgacattt atgacaagta gttggttgtg tgcctggttt
    73741 tgcaccgttt ccaccacaag tatgacagat ttcttcccga ttatacttga tttctttttc
    73801 tacaccaaaa atcgcttctt caaaagacaa gtcgaccgta tattgcaaat cagcaccttg
    73861 acgaggcgca tttggatcga ctgaccgacc gcctcctcca aagaaagagt cgaagatatc
    73921 ttcaaaacca ccgaagccgc caccagagaa gccgccgaat ccaccaaatc cgccaccagc
    73981 tccaccagca ccgtaatttg gatctgtgcc tgcatgcccg tattggtcgt atgcagcgcg
    74041 tttttgcggg tcacttaaaa tctcatatgc ttctgatact tctttgaatt tttcttccgc
    74101 atcaggttct ttattgatgt caggatggta ttttttcgaa agcttacgat aagctttctt
    74161 tatttcatct tctgatgctc cttttgagag ccctaagact tcataataat cacgttttgt
    74221 tgccataggc tttcctccta ttggttctca tcattttcac gtcgcttgtt atcatatcat
    74281 attttgtttg aaacaaaaac cgatacttca aactattttt caaaagaaaa agccaaagta
    74341 gcaactttgg ccttctctcg aaattcagtg aactgattat ttatcgtcgc catcgacttc
    74401 ttcaaaatca gcatcaacga catcatctgc tccgccttga gctgcttctg gattttcttg
    74461 agcttgttgt tgtgcagctt gttcgtatag tttaacagtc aagttttgaa cgatttcgtt
    74521 caatgcatcg cgtttagttt tcatttcctc gatgttgttt gcttcaacag cggcttttaa
    74581 ttcgtcacga gctgtttctg cttttttcac ttcttcttcg tccactttgc cttctaattc
    74641 tttcaatgtt ttgtccacag agaatagcaa tgcgtctaca tcattacgta ggtcaacttc
    74701 ctctttacga gctttatctg cttcagcgtt tgcttctgca tctttcacca tacgttcgat
    74761 ttcttcgtct gttagacctg aagaagattt gatcgtgatt ttttgttctt tttgtgtacc
    74821 tagatctttc gcagatacat ttacaatccc gtttttatca atatcgaatg ttacttcgat
    74881 ttgtggaata ccacgaggag ctgctggaat atctgtcaat tggaatcttc ctagagtttt
    74941 gttgtcagca gccattgggc gttcaccttg taatacatgg atgtctactg ctggttgatt
    75001 atctgccgca gttgagaata cttgtgattt acttgttgga atcgttgtat tgcggtcaat
    75061 caatttagtg aacactccac ccattgtttc gatacctaat gacaatggtg taacgtcaag
    75121 taaaacaaca tctttcacat caccagtgat cacgccacct tggatagcag cacccatagc
    75181 aactacttca tcagggttaa ctgatttgtt tggttctttt cctgtttctt tacgtactgc
    75241 ttctacaact gcagggatac gagtagatcc accgactaaa ataacttcgt cgatttctga
    75301 ttgtgacaga cctgcatctt ttaacgcttg acgtactggt acttttgtac gttctactaa
    75361 gtcagctgtt aattcatcaa attttgcacg tgtcaatgtc atttccaaat gcaatggtcc
    75421 agattctcct gctgtgataa atggcaagct gatttgtgtg cttgatacgc cagataaatc
    75481 ttttttcgct ttttcagcag cgtctttcaa gcgttgtaaa gccattttgt cttgagacaa
    75541 gtcaatgctg ttttcttttt tgaattctgc taccatgtag tcgatgattt tgttatcaaa
    75601 gtcgtcccca cctagatggt tgtcgccagc tgttgacaat acatcaaaga caccgtctcc
    75661 tagttcaagg atagatacgt caaaagtacc gccaccaagg tcgaatacta agattttttc
    75721 gtcgcgatct gttttatcta aaccataggc aagagcagct gcagttggtt cattgacgat
    75781 acgttctact tctagaccag cgatcttacc agcatctttt gttgcttgac gttgtgcatc
    75841 attaaagtaa gctggcacag tgataactgc tttttcgact ttttcaccta aatagtcttc
    75901 tgcgaatcct ttgatatatt gaaggatcat tgctgagatt tcttgtggtg tatatgattt
    75961 accttctaca tctactttgt aacctgcttc accgatatgg cgtttgattg atgaaatcgt
    76021 atttgggttt gtcacagctt gacgttttgc aacttcccct acttggattt ctccattttt
    76081 gaatgataca acagaaggtg ttgtacggtt tccttctggg ttagcgatga tttttgcttc
    76141 gtttccttcc aatactgcta ctgcagagtt agtcgtacct aagtcaatac cgataatttt
    76201 actcataatt aacgtctcct tctttaattg aaagtgtaag ttttatatcc gcacaattat
    76261 tgtgcaacaa tgaccatggt tggtcttaac acgcgatcat gtaatttgta gccttcttgt
    76321 agtacttcta caatcgtatc ggctggtgta tcttcagtcg ctggaacagt ttgtactgct
    76381 tgatgaagat taggatcaaa ggcttctcct ttagcaggga ttttttcaat tccttcttct
    76441 tccagtgcgt tacgcaaact ttccaagacc atttccacgc cttttttcaa acctgcccct
    76501 tgatcatctg acacttctgt ggctaatgca cgttccaggt tgtcaattga tggaagtaat
    76561 tttttggcta aatcttgtga acggtatttt tgtaattgct cacgctcatt ttttcctcga
    76621 tttgccatat ttgcgatttc agcacgagcc cgcaagtatt tatcttccat ttcttctaac
    76681 tcagctttta atttcgctgt ttcgaattct tccgcttcag cttctgaaat acccgaatct
    76741 tctgcagctt cgacatcgat ttccggttct ggctgagcat ctgtcatttc tttatctagt
    76801 tcttcttgat tttctttcac gatacagtct tcctttcatt attcagtcag ctgtttgatt
    76861 gctcttacta agaaagagag aacgatcagc tgcaaatagc ttcgttattc acattacgag
    76921 tttgacaagt caagcgaacg gtagtaatca gcaagtttag ctgctagttc tcttcgataa
    76981 acatcgacta gaccgaacat ccgagaataa ggcatactag taggccctaa caaggctatt
    77041 gtacctcttc catgaccatc tatctcgtaa cttgcttgaa tcatactcat attctgcaat
    77101 aaatcattgc ctaattcagc accaatcttg atatgaatat tgctatccat cggagtgatc
    77161 atttgtgtaa gtccgtctga gtctttcata aaagaaaaca tcgatttgaa ctgatcaaga
    77221 tcttgacggg gctcataatc caagagattc atttgtccac tgacataaac cttatcttca
    77281 aaaacatgac caagaacggt gtcaaataac tgagacatcc cttctgtcgt ttggaaatat
    77341 ttatgaagaa tcatcggaat ctccgtacga agtttatggt acaccgtcat cagaggatct
    77401 ccgactagac ggtcgtttac aatctgtacc attttttcta gttcctgact tcccatatat
    77461 tcgggaagag tgaacacttg gctttctaca ttccccatat ctgttacgac gatagcaata
    77521 atctgtcgat tattcaaggg tacgatacga aagccagtca gtcggcggtc ttttatttca
    77581 ggtcccaatg aaaaagtcgt atagcttgtc agctcagata atatctcagc agattgctta
    77641 ataatctcat tgatttcatg aaattctctg cctagagact gacgaatcag cagcaaatca
    77701 tcttctgcta cgcgagcagg ttttaacaaa tgatccacgt aataacgata gcctaaagca
    77761 gatggaatcc gcccagaaga agagtgagtc ttcaacagca atccttcatc ttctaatgct
    77821 ttcatatcat tgcgaatcgt tgctgagctg gccttgactc cctcagacat caatgttttg
    77881 gaaccaacgg gcacgccact actcgtatag tgttggatga tcagacgtaa aatgtcgttt
    77941 tgtcgctttg ttaacatctt cctcacctct cattagcact catatattct aagtgctaat
    78001 ccacttataa atatagcaag aagcccttct cctgtcaaga gaaagactcc attttttagc
    78061 actctaaaca caagagtgct aattctaaat aattgatgta aatccagtta tatcaacgtt
    78121 tcaatagtcc tttattgtat ttttgaactt tttttattta aattcagata aaaaacaaat
    78181 attctttaaa ctatttttca aacaaaaagc gctcaaacac attgttcccc aaaaaggtcc
    78241 ctcttggtgt caaataaaca cggtcttctt cattaacaag taacccttct tgctctaatt
    78301 cccttagcac atcaccgtac accgattcaa ttgttttttg atagcgatca tagaaatgtt
    78361 ttttagtaat ccctgttttt tttcttagtc ctaagaacat ttcttcttct atttgatttt
    78421 ttcgtgtcaa tttttcttct tccaataccg ggcgttcatt tgctcgtaat gggcgtaaat
    78481 agtgttggat tggtcctttg ttgcggtaac gaatatctcc aagataaccg ctagcaccag
    78541 ctccaaaccc aaaatagtgg gcattgttcc agtacatgag gttatgttga gattcatgtc
    78601 cggagagccc aaagttactt atttcatatt ggtgacgtcc atgcttttcc attgcttcaa
    78661 tcgtctcttc aaacattctg gtttccgttt cctgatcagg cagttcgagt cttccttgtc
    78721 gtacccagtt catgaacatt gttttgtttt cgaggatcaa tgagtacaaa gaatagtgag
    78781 gcagatccaa agccaaagct ttttccaaag tatccagata tccttctagt gtttgtcccg
    78841 gtaatgcata aatcaaatcg atgcttacat tggtaaaatt ttctgcttct aaaaattgca
    78901 tagtttgata cacatcttct gcggtgtgtt tacgtccaat ttttttcaat aagcgattat
    78961 caaatgtctg cactcccatg gataaacgat tgacgccata gtttttcatt acttgaagtt
    79021 tttcacgggt caaatcacct ggattcgctt ctacagtaaa ctcattacca ttttgaaaag
    79081 gcaggatctc tctagcacct gataacagtc gatcaagttg tttagcagat aaagaagttg
    79141 gtgtcccgcc ccctacgtaa agtgtttcta aattcgctgt cggatgactt tctagcatta
    79201 ttttcatttc attcagcagc atttccacat actcatctac tggctgccct tctaaaaaaa
    79261 ctttattaaa atcacagtaa tagcagatat gctcgcaaaa tgggatatga atgtacgcag
    79321 aaaccttgtt ttctgcggga tttattgttt ctatcattga aattctttct ccttacgtcg
    79381 aaaagtcgtg cctgttttcg accttcttaa aatcgcgttc aagcaccaac tcattgaaat
    79441 aagccgcata tttagaatca aggaaaccta gctctaaaaa tgcttgctta ttgtcatcgg
    79501 agctacacgg tgcttttaca gcctctcgat aaacggtaat cgcaaagctg accttcggca
    79561 ttaagtcaaa atctgcaaaa atatgaaaag ctattttcac agattcctcc ttaagtgctc
    79621 agaccacaac gctttgctta caacctctca tatacgcata ctaaacgtat ttggcgaaca
    79681 aatccactaa aaaatccaag aatcgacttc ttggatgatt ttttctttca ttaaactggt
    79741 tacctagtta tatatctcta gggttgtttt catgtctgag tgcccgatat gatttatttt
    79801 tcgtttctat aattactttt tgccttccag tttcttttaa tattgtactc aagcaagtgg
    79861 gaattggttc ttttgtcatc catgtatgca aaatgttata atgctggtaa acaaaaatga
    79921 ttacctgtca tttttattta gttcgtattt aattaagttg actatctgta tactctgtct
    79981 aaaacttaag aattgttgtt ttcgctgtcg ctacccaatt ttaatgaatg tctgtaggtt
    80041 aaaactgttg tccttgttat agatagtaaa ggagagcttg aaaatgaaaa ctgcgattac
    80101 gtttctatta gaggaatatg ccgattggga aggtgcttat attactagca cactaaacca
    80161 aaatgagaaa tggcaaaaca aaactgcttc tatccaatca gaggtcactt ccattggagg
    80221 attaaaaaca aaaatcgatt acttaatcga acaaatacct gaaaaagttg acctttttat
    80281 tatgatcggt ggcaattcat gggacataaa aaatcatcat ttatatcaaa taatcgataa
    80341 attgttaaaa acagacgtac cagtagctgc tatttgtggg gcagttgatt atttagctca
    80401 gagcggatta ttgcaaggtt acaaacacac cggaaatgcg caatttcctt ggttagaatc
    80461 ggaaaattat cagaataaag aagattttat agaacaacaa gctgtgaaag atcgtaattt
    80521 gattactgcg aatggaacag ctcctataga attcacagac ttgattcttc aagcagtcca
    80581 ttttgaaaca gaagaaataa gagaaaaaac gattcgtcta tacaaacttg gattctatga
    80641 ttactataaa aagtacggag atcctttctc ctaatcattc tcttcaatta aatactcctt
    80701 atcaatagtg tgacaagtaa ttttactgat gattatttgt cacacttttt ctgacattta
    80761 tcaaagaaga tacactctat ttatattcat agacaaggtt ttacggattc aaaaattcag
    80821 gattatgcta tactggtatt aaaaaaataa tgaggtattt tatatgaaaa agttaggttt
    80881 tattttattg ttggtctctt tattccttgt aggatgtacg tctcctagta aagaaaatag
    80941 tgatccatct gcgaccacag acaaaagttc aatcagacaa accagttcag ctgaaaaatc
    81001 aagtactcag aaatcagctt ctactgaaac gaatacatct tcaacaagca gtaaagtctc
    81061 agagcccaat acttcttcta catctagtag tacagttgag acaaatattt cttcttcaac
    81121 aatagacaca acctcctcac agtcttctca gtcaatagat ccgttagcag gatattctga
    81181 tctacaaatt gagtacgcac gtgtttggct agctattaga ggtaatactt ttagagatac
    81241 atcgggtgat ttcgaattac atgttattca ttatcctgca ggaacaccta tcgcccctta
    81301 tgatgcaggg agtgcagtct atccgaaaga tgtggttatg ctcactggga aatacagtta
    81361 ccagggagtt ttagtgtatt caagtaacca tgacgggaca atcactagtt atccagttcc
    81421 ttcacattgg caaatgcctg cagatcaaac atcttatcca gcgttcatta gagaaacaac
    81481 tcaagaaatc attgataatg catctgtagt agctattcct acaggaaatc ccaatgacgt
    81541 gaaacagtta atcgatgtga cagttataga taattagact ttctaatatg ttatacaaaa
    81601 agaagctgac agcattttgt cagcttcttt cactttcttt tctatttaga tttattggtc
    81661 tttgatagac tccaaggcag gaaaaaattt tttaaataaa cgtttgcaaa acagtcgctt
    81721 ttctatcttc taccgctact tctgcatagg caccattaat caatgtcagt tgtggcggta
    81781 catgaccaca atcaatatca tacaagatcg gtagttttaa ttcctttgac agatcttcgt
    81841 atacatcctt cattttataa tctaacaaat cctctgccgc acttctaccg aacatgatcc
    81901 ccgagctgcc atcaaaccag cctgccagtt tcatctgaac aagtgatctt cttaaatcaa
    81961 ctgacgatag ctcacagttt tctagaaacc acaagatcgg ctttccatca ttatactttc
    82021 ttttaaaaga ttggacatct ccataaggag taccgattaa atgcctgatc gtatcaatac
    82081 aaccacctaa taatcgtccc ttcatcctta ctgcatctcc gctgactgat tgccaatttg
    82141 ttggttcagt gagatggaaa acagaagatg atgaatgctc atggggccac actttttgat
    82201 acttttcaga agattgctgt agaatcgatt ctccttctct tgttttcagt acactttccc
    82261 acattgctgt cgtttcatcc aagtactctc ctcttaaatc aataaggtta gttccatgtg
    82321 cagtggctat ccctgttttt aatgtgacag caagtagcaa cgtactaata tctgaataac
    82381 ctactatcca ttttggttgt agagcatcaa aatcgacaaa atcgagaatc tcaatcaata
    82441 attctcctcc ccaagtcgga aagatcattt ggatattttc atcttgcatc atttgattga
    82501 attcatctgc tcgttttctt gctggacctg atttttcctt atcttgcgtc caaagcgtct
    82561 ttccagtaac tacttggaaa gatttttctt ccattctctt taaagctgat tcgagtaacg
    82621 aatggtgttc ctctgatacg cctgaggatg gtgcagtaac cccaatcgtt gcatttcttt
    82681 ctaataatgg ataacttatc atgttgcttc acctccaagt atgcactatt ttacttggtt
    82741 aattgttttt ttcgtttgcc ggcatcaaaa atatcggcat ctcaagtagc tggatgattt
    82801 tgtttaagtc aaccgtttgg atgaccatcg tttgatctgg tctacctggt gcaaaaacaa
    82861 gtttttcatt tgataagagc tcttcatcaa taataatcgg aatctgtttt tcataaccaa
    82921 acggagaaac agcgccctgc ttttgtcccg tttgttcttc catgcgttct gatgaaacaa
    82981 tagaaagcct tttaccgacg atcttcccta atgctttgaa atccgtttgt ttcgtagtaa
    83041 aagtcagata tacgtagtta ttatcttttt tatcttttaa gaataagctt ttggtctctg
    83101 tacctgtaaa tccttgttct ttctttatta ccaaagcatc ttcatttgta taaatggctc
    83161 gatgatgata caactcaaaa tatatatttt cgtgtaagaa tttctttgcc aagtcaatca
    83221 tttttatgtc tcttttctat tttattattt gagacatctt atcatataaa tatagcggtt
    83281 acaacattac ttgtgttttg ttcgtttttt atacataact attgtttttc tggtaaaata
    83341 aatcaaacca cttaatggag gcgttttaga atggaaaaat ttcagccgat catcaatcaa
    83401 atcaaagaaa aagaacatca acaaaagatc aaagaccttt ttgctaagat aacagaaacg
    83461 tatccccagc tagacacaac tgtaaaatgg aaccaaccta tgtttactga ccatggtacc
    83521 tttattattg catttagttt tgctaaaaat catttttcta tcgcaccgga aaaagcagcg
    83581 attcgtgccc ttgaaaaaaa tatccaagaa gcaggctacg tatatacgga taacgtcatc
    83641 aaagttcctt ggaaaagtgt aatcaactgg gaattgattg aacaattgat ttcatttaat
    83701 attgaagata aaaaaggtca tgataaattt tggcgataaa gctttatacg aataaacctt
    83761 ttactggcga ggaaactatt catcacctta tacaggtttt gttcaatcct atccttttta
    83821 tcatccctgg ttaaacactt aattgacaaa gtatctgcta tttttataag gagtctttct
    83881 tgtgctgaaa aaaatcactg attgaatggc tttgaatttt ctacttagta aaattatttt
    83941 ttcagcaatt ttcctgcaaa acttttgaat aaggaaaaaa tacgagaaaa tatcagtgat
    84001 ctttcataat actgcccatt attttcaggt atatttaaat ataatatcac tttaggagag
    84061 aacgaatttc tttagagaaa taaaagttag aattttctga cttgattttt acaatgacct
    84121 taattaaaat cgttctttct acatttcgtg attaagcaaa tatcaactaa gtcagtagaa
    84181 ccattcacat aggagggtga acattgaaag atttttactc agtaaatgaa ttagccgaac
    84241 aattaggtgt tactacacgt tctatcagaa attatcttca tgaaggaaaa ctaaaaggaa
    84301 caaaggttgg cgggcaatgg aaattttctg aacgtaatct ttttgagttc ctatacggag
    84361 atcaagcaga ggaagcagca aaagaaatgc agcgattcat gctaaatgca ccaatcacga
    84421 tgcgtttcaa ccttcaatat cgtgatttta cagcaatcaa tcaattccga gaacaattag
    84481 tccagtacca taacgatgtt tacgcaaata aaaaagaccg tcttttacaa tacgatcttt
    84541 ataaagacaa tcatgcggag atactaatcg gtggtaactt caattatgtc gtaaacttta
    84601 gtcaatggat caatgaaaaa ttattgatcc agacagatat ttcccttgta tcttaaacaa
    84661 ttaaaaagcg ctagaaattc cagagatgtt ggaaattcta gcgctatttt tttataagta
    84721 cttactgttt ggttcaaaca aatatttttt taataaatga aattttacca tctttatcct
    84781 caaataaaga ccgtgaccat gcttcctact acgatcagca ataatccgat aatcgttaat
    84841 tttttttctt ttggtgtctt attttcatgc aggatgtaca taccgcctaa tgtagagata
    84901 actacgttta gctgtgtaat gatatatgca gtagcaaccc cattttcatt tgctgaaaaa
    84961 atataagcca atgctgacac actaaagatg gctccaacga tcgttgcttt ccaactcttg
    85021 tcttcagaaa atgcggttgg tttacggaaa atcacataaa tcactgcccc taaaaagaca
    85081 ccgatcattt gcggaaagaa aatggaaagt ccgcttgcat caactagttt aggcaatgca
    85141 ctgtataccc aataaccaat acttgttgat gctaatagac taattccttt tgtgataccg
    85201 cctttttttc caggatcatc actgattgcc gttaaagcag aaccaaatac aagaagaatg
    85261 attgctgctg ctccaatgat tttccccata cttccagacc attctccaaa agcgaagaca
    85321 ccaatcaacg aggttccgac taactgtaat gcagtcgaaa ttggcatcgt tttagaaaca
    85381 ccaatcaagt tgaaagatgt atactgtcct gtttgtccaa taacccaaaa tgcaccagaa
    85441 agtaaactaa tcaaaaatgt agtcactgaa ataccagctg gagaagcgaa taattgaacg
    85501 agtaagccga caagcaccgc tccaatacca gttcctaata tctcatttgt tggtctgcca
    85561 ccaatctttt tcaaaatcag tggctggatc ccccagccaa ctgccgggat caatgcaatc
    85621 aataaaccca tttttattca cccttatcct tttccacctt ggaaagaagg atataaagtc
    85681 atcccaccat ctgcaaatag tgtaatacct gtaacataac tggattcgtc tgaagccaac
    85741 catgcagctg tcgccgctat ttcttttggt tcacctacgc gtcctagtgg gatcatactt
    85801 tccaagagtt ctttttgttc aggatcatca aattttgccg cattaatagg tgtacggata
    85861 gcaccagggc ctatactatt gattctgatt cccttcggtg catactccat tgctaccgtt
    85921 tcggtaaata attttacccc gccttttgaa gcagcgtaat gagcaaacgt tggccatggg
    85981 atctgttcat gaacagaaga catattgatg atatttcctt ttttattatt ctctgtaaag
    86041 taatttaaag ccgctttcgt tccgataaaa acgccagtca aattgacttt taacactctt
    86101 tcccaatctt caaggctaag ttcatgggtt ggatgctgat tttccatccc agcattatta
    86161 acccaaacgt ccagtgtccc aaaattttct aaagccgtat caagtaaacg ctgtattcct
    86221 tcttcagaac tgacatctgc ttgtacagag actgcttttc cgcctgcctc ttcgattgct
    86281 ttgactgctt tttctgctcc ttctttatcc gagttatagt tgacaactac attcattttt
    86341 tctttcccga atcgttgagc aatcgctgtt ccaatcccct ttgagccacc agttactact
    86401 gcgactttgt tttctaattc cttgtacata gtacccactc ctttttcata cctaaacctg
    86461 ttattacgga taacttttat ttccgcctta aagtgagtgt acaccaagat atatagtcta
    86521 aagcaaatga tacgctctag caatcgtttt catgaattgc tagtgtcctt ttatttctat
    86581 aaagaaagag gttgtgacag aagtggtcag cttcaagaaa tttcggctta tttccgaaga
    86641 agctacttct gaaaaaccat ttatttggaa aaaaaggctg tgacaagact tttgtcacag
    86701 cccctttcct gggcttattt atcacccatt ttattgtaat tgctagttat acataaacaa
    86761 gagattttat gcataatgtt ttattgctga gaaaaatatt cagctgttgc ttgttcatcc
    86821 tccttgagtt gttcaatcaa ttcctctaca ctagaaaatt tcacttgatc tcttaaaaat
    86881 tgattccagc gtaccgcgac atgttcacca tagatatctt gattaaagtc caaaatatac
    86941 aactctacag tcagctcccg tccttcaccg aatgtatcat tatgtccaat tgaacccatg
    87001 gctggatacc atgtttcccc aatttttatt tccgacacat aaacaccttc tttaggcaaa
    87061 tgaaccgtgc tctttacttt gacatttgct gtagggaatc ctagtagtct gcctcgtgca
    87121 tcgccatgga caactacccc ttctacctca tatgtgcaac ctaatagttt tgctgcttct
    87181 tttacttgtc cgctgtctag taatccacga atacgggtag agctgatttt ttcaccttgt
    87241 tcttcttctt tagaaactgt gacgattttg aatcttcctt tggcatattc aggaaaatga
    87301 gcgacatctg caatgtcttt tggtccatac gtataatcaa aaccggaaac agcatatttt
    87361 gcatgtaacc ctacgatgta ttgatcaaca aattcctgcg gtgctaaatg agcaaaagaa
    87421 gaagtaaaat caacttcata taaataatct atacccaaag cggccatttt ttcttctttt
    87481 tgcttaaggc tagtcaaata tttcacgctg ctaggatcga tctttttaaa gacaatagat
    87541 ggatgctgat tgaaagtcat caatgctaat ttcaatcctt ctttttgtgc aatttccata
    87601 cctgtcttta tgactttctg gtgtccgata tgcacgccgt cgaaaaatcc cagcactaaa
    87661 acgacatcgt cttctggaat ttgttctgat tggtaaggat gtctgatctt gatgatattc
    87721 attcgttatt cctcatttct caatacttta ctaggtttta atttgttttt ttctttcggg
    87781 tttggctgat aaatactgac aacttttcct ttataaaaca aagcaatttc ttctgacggc
    87841 atttctggga gcgcaaatac agtataatca agtctcatac cgttttttac tttctgccat
    87901 acttcatcag taatatctac tcgtttgaac cgttccactc ctttttctat tggcagcaaa
    87961 caatcatcga ttgtcccatt tttcacagct tgagctactt cttctaatgt cagagcatcc
    88021 ttctgggaca taccggcact tgctgttcgg gtcagatcag acatgtgcgc agggtaacca
    88081 agtttcttgc ctgtatctac agctaatgtg cggacatagg ttcctttccc gcattctact
    88141 tcgaagcgcc aagaaatggt tcctgtcact tcgtctcttg tcaattcact tgtccggata
    88201 aaacggtaaa tctgagcctt tctaacagga cgctccactg tttcattatt gcgggcatat
    88261 tcatataacc gcttaccgtt gacttttacc gctgagtaca ttggtggtat ctgggtgatc
    88321 tcaccaataa atgaagccat cacttcatct attttttttt cagataaaga catatctact
    88381 ggttttgttt ctacccgttc tccggatcga tcttccgtcg ttgtactgaa acctagagtt
    88441 atctcgccta catagatttt cccagaatct gtcaaatatt cgataacttt tgtggctttt
    88501 ccaatacaaa tgggcaacac accgtctacg tctgggtcaa gcgtaccccc atgtccgatt
    88561 tttttcgtat gtaagatttt tcttaatttg aatacgcaat catgacttgt cattccgcgt
    88621 tctttccata aaggtaataa cccgtccatg tcttttctcc atttcatttt tgatttaact
    88681 gaattattat aacacattgc atcaattact gacgaatttg acatcataat gaacggtttt
    88741 tatttttcgg caataaaaac gtaacaaaat tcatgctcac gtaaatagaa atcatgttat
    88801 gcttttttaa aggagggaat agaatggaag attttttctt tgcaccattt gattggattt
    88861 atgggtggct tacaggtaaa tagtttggtt ttcacttccc aaaaacgaaa aaaaagactg
    88921 gccattcttc cagtcttttt tccgtttttt ttatttattt tttcagtttc ttaatcaatg
    88981 taaaaaattc tattttgcgg gatcgatttt atcattttat tggtcaagat ttttccattt
    89041 ccaatccaat acttctggca gatcaatacc attttcacga atatagtttt gatgttcttg
    89101 taatttctga tccatttttt tcgcaaaatc ttctgcttga cttcctttga tttttaaagc
    89161 tgcgtctttt gccaaatgat aacgatcaag ttcatttact acacgcatgt caaatggtgt
    89221 cgtgatatct ccattttctt tgtagccatg aatcattaaa tgatggttat gacgatcaaa
    89281 gaaaatcgtg cggaccaatg tttcataacc gtggaaagca aataagatcg gtttgtcttt
    89341 tgtaaaatat tgatcaaatt cttcatcgct caacccacgc ggatcttgac ttggatgacg
    89401 taatttcaat aaatctacga cattgatgaa ccgaattttt agttttggga attcttccag
    89461 cagcaaagtt acagctgcta atgcttctaa gttagattcc gttcctgcag cagcaatgac
    89521 caattcaggt tcctcctctt ttgctgtcga agcccaatca atgattttca agccttcatt
    89581 cactaagacg gctgcttctt ctgctgagta aaattgagca cgcggatgtt tggaagagat
    89641 gatcaaattg attttttctg acgagcggaa tgctttatcc atgactgcga gcaatgtatt
    89701 tgcatccgca ggcagatatt cacggatgaa ctccgccttc ttttctgcca aatgtgtcaa
    89761 tattcctgga tcttggtggc tatatccatt gtgatcttgc tggaagactg ttgagcttgc
    89821 aatgagattt agcgaaggat aatcatttcg ccaagaaagg tcatgtgatt tccgcatcca
    89881 tttgaagtgc tgagtcaaca tagagtcaac cactcgcaag aatgattcgt aacttgcaaa
    89941 aaaccatgcc gtccagtcag aacgtaccct tctaagaacc cttcatcttg gtgttccgat
    90001 aattgactgt cgatgacgcg accagatggc gaaagccatt catcattttc tggttcgatt
    90061 ttttccatcc attggcgatt tgtcgttttg aaaacttgat tcaatcggtt tgattttgtt
    90121 tcatctggtc caaatatacg gaaattttct ggatttttct caatgatctc gcgaacgaat
    90181 ttaccaagtt cggtcatatc ttctgcttta acggagcctg gtttttcaaa ttgcaaagta
    90241 tattttttcc aatctggcat aataagcggt cttggatcga ttccaccatt ggtgatagga
    90301 ttttttgcca ttctttggtc accagtaggc gcgatttctc tgatttcttc taaaatacgt
    90361 ccttgtgcat caaataattt ttctggttca taggatttca gccaacggag taaagcatct
    90421 gcatgatcca tatgttcttg atctacagga atcggtactt ggtgtgctcg gaaggttcct
    90481 tcaattggtt ccccgtccca ttcttttgga ccggtccatc cttttggtgt gcgtacgatc
    90541 aatactggcc attttggcat cacgacatct gttgctgtct tcaggcgagc ttctttttgg
    90601 atggatttaa ttttctcgat tgcttgatcc attttttcag ccataacagg atttaatttt
    90661 tctgaatcat ttccttcaat aaagaaaggt tcccagccaa gtccgttaaa gtaatttgct
    90721 aattctccat ctgatttacg tgccaagatc gttgggttgg ctatttttgc accatttaaa
    90781 tgaaggatcg gtaaaacagc tccatctatc actggattga taaagacatt tgagaaccag
    90841 cttccagcta aaggaccggt ttctgcttca ccatcaccaa tcacgacagc agagattact
    90901 tcaggattgt ctaatacagc tccgactgca tgtgaaagag agtatccaag ctctccgcct
    90961 tcatggatag aacctggtgt ttctggtgct gcatgagaag caatgcctcc aggaaatgaa
    91021 aatcgtttga ataatttttg cattcctgtc tcatcttccg ttacttctgg atagatctct
    91081 gtgtaacttc catctaaata agcattcgat accatgactt gtccgccgtg tcctggccct
    91141 tcaatataaa acatgttcaa atcatattta ttgatgactc ggttcaaatg gacataaata
    91201 aaattttggc caggaatcgt tccccaatga ccgattggat gttttttgac atcttcgggt
    91261 ttcagtgtac gtctcagtaa ggggttatct ttaagataaa gttgcccaac agaaagataa
    91321 ttagcagcac gccaccaagc cgtcatttta tcaaagtatt ctttactaga ataatccata
    91381 cataacactc cttttcatta ttactcttat tctagcgcag atactcccaa ttgaaaccta
    91441 ataagcactt ctgttcattt gtttggattt tatatctagc caaatgaaca ggtataaaaa
    91501 accacgaaat ttttcctttc gctgacgttt tttacattga tccaaaaaac ttgtcgttat
    91561 cacaatggct gttccgcagt tcatttcgct cctcatcatg cataatttgc tgaatgacgc
    91621 tgggccagtt aacacattgc tggaaaactg gggctggatc gagcaattcc tttcctgatt
    91681 gatccgtttt atgtaaaagt ctctgttatc tttgtcaata tgtgaattgg tatcccagct
    91741 actatgctaa tttctacagg gattatccaa aatttggatc gtgaccaaat cgaagcggcg
    91801 taatcggaaa tatcaataac ttcaacgtga tttttctttt aactgtcaac ggaccgacaa
    91861 actcaaactt ttatggtgca ggttccactg atcttctagt tacttggcta tacctgactg
    91921 tcactaaaat agattacaat ctagcttccg ttatcggtat cttgatcttt atctatatgc
    91981 aaaaatttat atactactag aaaaaagaaa gtcgaatttt ttacttttct ttttctcttt
    92041 tttggttagc tgacacgccg caagactaaa gtcatggaac tcttaggtaa tacgtcttaa
    92101 tgaaaacaaa aaaatcccgc aacccctg
//
LOCUS       DAFENC010000008        80048 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.008, whole genome shotgun sequence.
ACCESSION   DAFENC010000008
VERSION     DAFENC010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 80048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80048
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.008"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            125..1168
                     /locus_tag="LP493_000728"
     CDS             125..1168
                     /locus_tag="LP493_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HBL2132896.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(1230..1694)
                     /locus_tag="LP493_000729"
     CDS             complement(1230..1694)
                     /locus_tag="LP493_000729"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBL2132897.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            1940..2887
                     /locus_tag="LP493_000730"
     CDS             1940..2887
                     /locus_tag="LP493_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL2132898.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(3098..5170)
                     /locus_tag="LP493_000731"
     CDS             complement(3098..5170)
                     /locus_tag="LP493_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBL2132899.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(5103..5480)
                     /locus_tag="LP493_000732"
     CDS             complement(5103..5480)
                     /locus_tag="LP493_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HBL2132900.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(5609..6187)
                     /locus_tag="LP493_000733"
     CDS             complement(5609..6187)
                     /locus_tag="LP493_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL2132901.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINNFIATLP"
     gene            6319..7611
                     /locus_tag="LP493_000734"
     CDS             6319..7611
                     /locus_tag="LP493_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBL2132902.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(7671..8789)
                     /locus_tag="LP493_000735"
     CDS             complement(7671..8789)
                     /locus_tag="LP493_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HBL2132903.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(8803..10224)
                     /gene="arcD"
                     /locus_tag="LP493_000736"
     CDS             complement(8803..10224)
                     /gene="arcD"
                     /locus_tag="LP493_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HBL2132904.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLITDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(10470..11591)
                     /gene="mnmA"
                     /locus_tag="LP493_000737"
     CDS             complement(10470..11591)
                     /gene="mnmA"
                     /locus_tag="LP493_000737"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HBL2132905.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            11995..12594
                     /locus_tag="LP493_000738"
     CDS             11995..12594
                     /locus_tag="LP493_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HBL2132906.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(12732..14018)
                     /gene="efmA"
                     /locus_tag="LP493_000739"
     CDS             complement(12732..14018)
                     /gene="efmA"
                     /locus_tag="LP493_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HBL2132907.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(14289..14633)
                     /locus_tag="LP493_000740"
     CDS             complement(14289..14633)
                     /locus_tag="LP493_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HBL2132908.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(14770..15915)
                     /locus_tag="LP493_000741"
     CDS             complement(14770..15915)
                     /locus_tag="LP493_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBL2132909.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(16095..17069)
                     /locus_tag="LP493_000742"
     CDS             complement(16095..17069)
                     /locus_tag="LP493_000742"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBL2132910.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(17149..18024)
                     /locus_tag="LP493_000743"
     CDS             complement(17149..18024)
                     /locus_tag="LP493_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HBL2132911.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            18154..20061
                     /locus_tag="LP493_000744"
     CDS             18154..20061
                     /locus_tag="LP493_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HBL2132912.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(20602..23880)
                     /locus_tag="LP493_000745"
     CDS             complement(20602..23880)
                     /locus_tag="LP493_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HBL2132913.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(24151..24696)
                     /locus_tag="LP493_000746"
     CDS             complement(24151..24696)
                     /locus_tag="LP493_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBL2132914.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(24708..25400)
                     /locus_tag="LP493_000747"
     CDS             complement(24708..25400)
                     /locus_tag="LP493_000747"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HBL2132915.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(25419..25703)
                     /locus_tag="LP493_000748"
     CDS             complement(25419..25703)
                     /locus_tag="LP493_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132916.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(25716..26279)
                     /locus_tag="LP493_000749"
     CDS             complement(25716..26279)
                     /locus_tag="LP493_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBL2132917.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            26507..27169
                     /locus_tag="LP493_000750"
     CDS             26507..27169
                     /locus_tag="LP493_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HBL2132918.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            27293..28489
                     /locus_tag="LP493_000751"
     CDS             27293..28489
                     /locus_tag="LP493_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBL2132919.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(28590..29966)
                     /locus_tag="LP493_000752"
     CDS             complement(28590..29966)
                     /locus_tag="LP493_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2132920.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(30003..30869)
                     /locus_tag="LP493_000753"
     CDS             complement(30003..30869)
                     /locus_tag="LP493_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HBL2132921.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(30958..31983)
                     /locus_tag="LP493_000754"
     CDS             complement(30958..31983)
                     /locus_tag="LP493_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBL2132922.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(32001..32675)
                     /locus_tag="LP493_000755"
     CDS             complement(32001..32675)
                     /locus_tag="LP493_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2132923.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(32859..33752)
                     /locus_tag="LP493_000756"
     CDS             complement(32859..33752)
                     /locus_tag="LP493_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL2132924.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(33826..35523)
                     /locus_tag="LP493_000757"
     CDS             complement(33826..35523)
                     /locus_tag="LP493_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBL2132925.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(35516..36829)
                     /locus_tag="LP493_000758"
     CDS             complement(35516..36829)
                     /locus_tag="LP493_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBL2132926.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(36829..40866)
                     /locus_tag="LP493_000759"
     CDS             complement(36829..40866)
                     /locus_tag="LP493_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBL2132927.1"
                     /translation="MVVDERIDNQELQENETDTEDSAEIQRSEENEMEKLDEPIVPSG
                     QALQRIQRQLFNGILERLGPTATQDPYEYIYPSGEVENEQHRYPKFTTNDYTKVLGNW
                     TQSNERYQGDKGSPYDGENLIDDSDYTNGGANWRNYDYATNNGSTAGEEDRNVPAQTV
                     QLWGNERNFENSYLDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEKK
                     EISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMVN
                     FYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETLY
                     KDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDVL
                     FRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGSS
                     NNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAIG
                     RNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVSP
                     FGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYKF
                     SPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSSS
                     IRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFETK
                     MPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEYT
                     SGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNIN
                     KLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDGK
                     YVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRLY
                     DNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTLD
                     GAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQPL
                     HLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIIDG
                     VLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPNDS
                     SLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTLK
                     VEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYILL
                     AAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(40879..41337)
                     /locus_tag="LP493_000760"
     CDS             complement(40879..41337)
                     /locus_tag="LP493_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL2132928.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(41635..42153)
                     /locus_tag="LP493_000761"
     CDS             complement(41635..42153)
                     /locus_tag="LP493_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBL2132929.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(42155..42771)
                     /locus_tag="LP493_000762"
                     /pseudo
     CDS             complement(42155..42771)
                     /locus_tag="LP493_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
     gene            complement(42768..43631)
                     /locus_tag="LP493_000763"
     CDS             complement(42768..43631)
                     /locus_tag="LP493_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL2132930.1"
                     /translation="MTANDGLFQKDQCESANKKILSYVLMTVIGIILIIPLLWMVFTS
                     LKPMEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFI
                     AYGFAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGN
                     AFNIFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWN
                     DFLGPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFI
                     EGMDLTGGSKG"
     gene            complement(43618..44529)
                     /locus_tag="LP493_000764"
     CDS             complement(43618..44529)
                     /locus_tag="LP493_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2132931.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(44570..45904)
                     /locus_tag="LP493_000765"
     CDS             complement(44570..45904)
                     /locus_tag="LP493_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL2132932.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKIFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            46112..46942
                     /locus_tag="LP493_000766"
     CDS             46112..46942
                     /locus_tag="LP493_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBL2132933.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(47186..47504)
                     /locus_tag="LP493_000767"
                     /pseudo
     CDS             complement(47186..47504)
                     /locus_tag="LP493_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028215.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(47626..47820)
                     /locus_tag="LP493_000768"
     CDS             complement(47626..47820)
                     /locus_tag="LP493_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132934.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(48325..48510)
                     /locus_tag="LP493_000769"
     CDS             complement(48325..48510)
                     /locus_tag="LP493_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132935.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(49360..49701)
                     /locus_tag="LP493_000770"
     CDS             complement(49360..49701)
                     /locus_tag="LP493_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBL2132936.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(49701..49931)
                     /locus_tag="LP493_000771"
     CDS             complement(49701..49931)
                     /locus_tag="LP493_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL2132937.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            50218..50556
                     /locus_tag="LP493_000772"
     CDS             50218..50556
                     /locus_tag="LP493_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132938.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(50761..51000)
                     /locus_tag="LP493_000773"
     CDS             complement(50761..51000)
                     /locus_tag="LP493_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBL2132939.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(50976..51323)
                     /locus_tag="LP493_000774"
     CDS             complement(50976..51323)
                     /locus_tag="LP493_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBL2132940.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(52055..52636)
                     /locus_tag="LP493_000775"
     CDS             complement(52055..52636)
                     /locus_tag="LP493_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL2132941.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(52819..53445)
                     /locus_tag="LP493_000776"
     CDS             complement(52819..53445)
                     /locus_tag="LP493_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBL2132942.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(53467..54798)
                     /locus_tag="LP493_000777"
     CDS             complement(53467..54798)
                     /locus_tag="LP493_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HBL2132943.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(54953..55354)
                     /locus_tag="LP493_000778"
     CDS             complement(54953..55354)
                     /locus_tag="LP493_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBL2132944.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(55440..55646)
                     /locus_tag="LP493_000779"
     CDS             complement(55440..55646)
                     /locus_tag="LP493_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132945.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(55741..57243)
                     /locus_tag="LP493_000780"
     CDS             complement(55741..57243)
                     /locus_tag="LP493_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HBL2132946.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(57261..57716)
                     /gene="argR"
                     /locus_tag="LP493_000781"
     CDS             complement(57261..57716)
                     /gene="argR"
                     /locus_tag="LP493_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBL2132947.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(57814..58431)
                     /locus_tag="LP493_000782"
     CDS             complement(57814..58431)
                     /locus_tag="LP493_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBL2132948.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            58652..60025
                     /locus_tag="LP493_000783"
     CDS             58652..60025
                     /locus_tag="LP493_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2132949.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            60100..61212
                     /locus_tag="LP493_000784"
     CDS             60100..61212
                     /locus_tag="LP493_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBL2132950.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(61284..62921)
                     /locus_tag="LP493_000785"
     CDS             complement(61284..62921)
                     /locus_tag="LP493_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HBL2132951.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(63089..63697)
                     /locus_tag="LP493_000786"
     CDS             complement(63089..63697)
                     /locus_tag="LP493_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL2132952.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(64081..65232)
                     /gene="queG"
                     /locus_tag="LP493_000787"
     CDS             complement(64081..65232)
                     /gene="queG"
                     /locus_tag="LP493_000787"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HBL2132953.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(65251..66003)
                     /locus_tag="LP493_000788"
     CDS             complement(65251..66003)
                     /locus_tag="LP493_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132954.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(66144..67094)
                     /locus_tag="LP493_000789"
     CDS             complement(66144..67094)
                     /locus_tag="LP493_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBL2132955.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(67095..67934)
                     /locus_tag="LP493_000790"
     CDS             complement(67095..67934)
                     /locus_tag="LP493_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBL2132956.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(67931..68677)
                     /locus_tag="LP493_000791"
     CDS             complement(67931..68677)
                     /locus_tag="LP493_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBL2132957.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            68915..70285
                     /locus_tag="LP493_000792"
     CDS             68915..70285
                     /locus_tag="LP493_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2132958.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(70340..71236)
                     /locus_tag="LP493_000793"
     CDS             complement(70340..71236)
                     /locus_tag="LP493_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL2132959.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(71350..71520)
                     /locus_tag="LP493_000794"
     CDS             complement(71350..71520)
                     /locus_tag="LP493_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132960.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(71517..72194)
                     /locus_tag="LP493_000795"
     CDS             complement(71517..72194)
                     /locus_tag="LP493_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBL2132961.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(72285..73190)
                     /locus_tag="LP493_000796"
     CDS             complement(72285..73190)
                     /locus_tag="LP493_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBL2132962.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            73365..74819
                     /locus_tag="LP493_000797"
     CDS             73365..74819
                     /locus_tag="LP493_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2132963.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVDPSH"
     gene            74835..75866
                     /locus_tag="LP493_000798"
     CDS             74835..75866
                     /locus_tag="LP493_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBL2132964.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            75873..77060
                     /locus_tag="LP493_000799"
     CDS             75873..77060
                     /locus_tag="LP493_000799"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HBL2132965.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            77216..78598
                     /locus_tag="LP493_000800"
     CDS             77216..78598
                     /locus_tag="LP493_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBL2132966.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            78725..78955
                     /locus_tag="LP493_000801"
     CDS             78725..78955
                     /locus_tag="LP493_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132967.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(79155..79823)
                     /locus_tag="LP493_000802"
     CDS             complement(79155..79823)
                     /locus_tag="LP493_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HBL2132968.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
BASE COUNT        22895 a        16756 c        14325 g        26072 t
ORIGIN      
        1 tattcgaaac aagaggtcgt acaagacttt tgtcacgacc tcttgttctt ttgtcaaaat
       61 actggtttag tgctactatg ttcgagtatg cttttagtat ttattgacga aaggaaccga
      121 tcaaatgaaa tcattgtcac atccaataaa atctgtaaag gattcagcgg tccgcgaaat
      181 cttacccggt ttactgcttt cttttgccat cgctgccttc agcaggcttc ttgctattta
      241 tctgccacag ttaggtggag cgactattgc tattttattg ggtattttat taggaaatac
      301 tttttttaaa cagcctgttc tagcaatcgg cacaaaattt gctgaaagca aactattaga
      361 attctctgtt tttttactag gtgcaactgt cacagctcaa acgattgctc aaattggtgt
      421 aaaaggaatt gtttttgtgt tactgcaaat gtcagtcact atcatcggtg cttacttgat
      481 tggtaaaaaa ctgcaattca gcgatacttc ttctttgatg atggctggag gaaacgctgt
      541 ttgtggttct tctgctattg cttcaatcgc cccttccatc catgcgaaag aggaagaaaa
      601 aggacagatc atcacactag tcaatctact gggtactgtg atgatgttga ctctcccttt
      661 tcttggatta cagttgtttg gtggaaatct cattgaaaaa agtgcacttt tgggtggtac
      721 actccaatct gttggtcaag tagtcgctgg ggcaagctta cttgacaatt ctgttgtcga
      781 attcgccatg ctatttaaga ttctacgtat tatgatgctc gttgttgttg tctatctgtt
      841 tgaaaaattc atgcacaaga aacaaccagc tctgtttgaa acgccaactg atacgcagaa
      901 aaaacgaaaa ttaccgcttc cttggtatgt attagggttt gtgatctttt gtttggtcaa
      961 cagcttgttt tctttacctg tagttattga ccaatcggca cattttatca gcagctggtt
     1021 tgagatcact gctttagcgg caattggtct gcgtttagac tttgcaaaat tcatgaaaga
     1081 aggtacacgc ttcttatctt atggattagc tgtcgggctt ctccaaacag tgatggcttt
     1141 actatttatt tggctgatca aagtttagaa tgaacatgaa aaaacagttg tgattctcgc
     1201 atggaacaat gtccgaatca caactgtttt taattttgca gatatccttc taacaacaac
     1261 aattggcgtt tgatttcaac cccatctatt gcgtttccca tatatcctgt cagttttcca
     1321 ttttgcccga tcactcgatg acaaggaata acgattggca atggattggt tcgatttgcc
     1381 tgcccaatcg ctcgcacagc tttcggacta tcaacagcaa cggctacttc tttatacgtt
     1441 cggatttctc cataaggaat ggtcgacaaa gctttccaga cattttgctg aaaaggcgta
     1501 cctctcttta tagataaagg aacatcaaat tcttttcttt ttcccgcaaa atattcttca
     1561 aactgttctt gtgtgcgcgt taaaattcgc tgattcgctg attcgctttc tgaaattggc
     1621 tgaaaagata cagcagtcaa tccggattca tctgcatcta accataaaaa gccgataggt
     1681 gtgtgtattt tcattttgtt tgctcctagt caatagactg gaacttcctc ctttttctct
     1741 atccaaaact acttgccaac taataaaaat tgttcttaaa agtttgataa accgaggaaa
     1801 catggtaaac taaatacgtt agtttacaaa aagaatacct gttcttttac gtaaaatcaa
     1861 attttaaagg tgttatttaa ggtttattaa attttgaatg taaaccatat ataaacatac
     1921 gattgaaagg atagaaacga tgaaagtatc aattgttgtc ccatgtttta atgaagaaaa
     1981 aactgttcct cttttttttg atgaggttga aaaattcaaa ggtgcccatg agttcgaata
     2041 tttgtttatt gacgacggat caaaagacgg tacgttagca gcaatcaaga agctagcctc
     2101 agcttatcct tatgtccgct ttgtctcatt ttccagaaat tttgggaaag aagcggctct
     2161 gtacgctgga ttgcaagctt ctacaggaga tttagtgacc gtgatggatg ttgatctgca
     2221 agatccgccc gaactgcttc ctgagatgat caaccggatc actacttctg atatcgattg
     2281 tgtcggcacc cggcgttcga ctcgtgaagg cgagcctgcg atacgcagtt tctttgcgaa
     2341 aaaattctac cagttgatca ataaaatcag cgatacagaa atggtcgatg gcgctcgtga
     2401 tttccgcttg atgactcgtc aaatggtgga tgccgtccta gaattaacag aatacaaccg
     2461 attttcaaaa ggattattta gctgggtcgg atttaaaaca gaatatattt cttatgaaaa
     2521 ccgcgaacgt gtggctggcg aaacatcttg gtccttctgg aaattattca actactcgat
     2581 tgatggtatc gtgaacttct cggatgcacc gttaacgatt gcttcattta tcggcgcttt
     2641 gtcttgtgtc ggttctggta ttgcaatttt gttcattatt ttgcgggcat tgttgtttgg
     2701 tgatcctaca tcaggatggc cttccatggt ctcgatcttc ctgttcattg gtggaatcca
     2761 attgttatgt cttggaatca tcgggaaata tattgggaaa atcttcttag aaacgaaaca
     2821 gcgtcctgtt tatatcataa gagaaacaga aaaagtgaag ccaaatgaat tgaagcctca
     2881 ccaataatat acgtcaaatg aagtaaacat ttttttaaat gaaaaaggac tgtgacaaaa
     2941 gtcttgtcac agtccttttt tccgaataaa tggtgttcca gaagtagctt cttcggaaat
     3001 aagccgaaat ttcacaaaaa tttgagaagc aattttcgta aattccttct tatttcttga
     3061 agctgaccac ttctatcaca acctctttca tatcttatta cttcttcatt gctgctttta
     3121 gtgctgctgc taatgggctt tcttctggtt cttctgcttg tgcatatttt ttcagcaagc
     3181 gtcgttcttc atgtttggtc attttcttct tctgctcttt tttatcaagc aatttttctg
     3241 tcgttccatc gtatttacaa cggaaataag caccgttttt accttcgatg atttccattt
     3301 tccggtgaca ttgcgggcat cgatgattag agacttttgg atcttttctt ctgcggtagt
     3361 tgcaatctga attggtgcag acatagattt tgccgtcacg tgtgtttttc tcgcgcagat
     3421 tggccccaca ttctgggcat ttcttttggg taatcgagaa atcttgatat tcttgtttgc
     3481 ttgatttgat ctcattcacc aagcgttttg tttctttttc gattccattc aagaaggttc
     3541 ctgcttgttt ctttcctgca gcaatagctt caaggtcttt ttcccagctt tctgtcaaat
     3601 ctggtgttac taaagaggga tttaccaata ctaataattg cttaccttta ggagatactt
     3661 gcagtccttg aggggtacgt tccatcagtt cagatttgat tagtttctcg ataatctctg
     3721 cacgcgtagc tggggttccc agactgtatt tttccatttg accaagcaag cttgcttctg
     3781 acaatggttt aggcggtgca gatagttctt ttttgatggc gaaatcggga ttgattctca
     3841 ttcctttttc ccatttgact gtttccgtct cagtttcagt ttcgcctttc catcctgctt
     3901 ggacgacacg attttgccga aaaatgaatc gttctttacc aaattcaacc gtaacttttg
     3961 tttggctgac tttatggggt tgagcaaaca gtcctaaaaa acgagagaca atcatttgat
     4021 agatttttcg ctcttcatta cttaattttt cataacgtgc tctgttttca gttggcaaaa
     4081 gtgcatggtg atcggtcact ttactgtctt ggaatacttt tgtctgttgg acgatggctc
     4141 cgtttttcaa atactgcttg acctcaggag caaagtcgct gactgcttgc aatcgttctt
     4201 tcatcgtact tttcatgtca tttgtcagat atttgctgtc tgtacgcgga taagtaacga
     4261 tcttatgggt ctcatacaaa ctttgtacaa gacttaatgt tttctttgca gaatagccat
     4321 agcgttgatt ggcttctctt tggatctctg ttaaatcata aggcaatggc gcagattccg
     4381 tttttaattt ttcttggact tctgtgacag ttcctttgct tgtactgatc aattgaacaa
     4441 gtttttgtgc ttcttcttgt gtttttaaag caaattgatt tttttgaagc attttggctt
     4501 gttcttttcc agcttgcaac gtgatcgtga aatacgtttg tggacggaac tgctcgattt
     4561 tcttttcttg gtctctcact aatgctagtg tcggtgtctg cacacggcct gctgataaat
     4621 tatccgcgta cttcacagtt aaggctctgg tcacattcaa tcctaccagc cagtccgctt
     4681 ttgcccgggc aagagcagat tcatacaatg catcatattc tttcgcaggt cttagttgct
     4741 tgaatccagt tttgattgct ttatctgttt gagaagagat ccataaccgc ttcactggtt
     4801 tattgaaatg cacatactct aagatccagc gagcaacaag ttccccttct cttccggcat
     4861 ctgtcgcaat gactgcttct gagacatctt ttcgctgagc cagctgcttg attgctttta
     4921 attgatgtcc tgttttagga agtggtttga ttcctagttt tttagggatc attggcaacg
     4981 tgtccatttg ccagctctgc cattccttat tcagatcttc cggcattttc aatcctaata
     5041 aatgaccaag ggcccaagta acgatcacct tgggtccttc ataataattt ttgtgctttt
     5101 gattagcacc aagcaccttg cttaggtctt tcgcaacgct tggtttttcc gctagaatta
     5161 gttgtttcat aaaattcctt tctgctttct actgtgatgg gctgatgatt tttcaacaac
     5221 gcaagtccct tgtattgctg taaatcatcg tcacactctt cacaccagcg ctcatctccg
     5281 tcattccaaa aggcgctgag aaagttactt tttgcattga tatattcata attttgatgg
     5341 atttcgttcc attgtttttc gtacgcttgt cgtgcttctt cgaaagactc gaatgtttct
     5401 tcttcttcaa tatcttcttc ccagtcttca aaaaaccacc aaggctcatt gtccccgaac
     5461 atggtaatta cttgatacat actcgtgctc cttctttcag cttttctaga ctcatcttag
     5521 tcacttttca agaaagttgc aagaattttc tcttataaaa gggtcattta atgaacatct
     5581 taaaattgtt acaaatgaat ctgattgttt aaggcaaagt agcgataaag ttattgatca
     5641 tccaaaaata gctgtcttct ggatcgattg ttggttcttt tgtaaagtat cctaaaaaac
     5701 gtaaggaaag ataaccgtgg atcatactac gaagttccct gcttcgatga actttttctt
     5761 ctttcgttaa ttgaaaagcc tcaaatatct gcaaaatgat ctgattcgtt tcatggattc
     5821 catctaataa aacagcttca ttggtatgcg gtacactgat cagtaactca tacactgctt
     5881 gatttgaaaa agcaaaggat cgataagttt ctgcatagat ctgcagtgct tcctgaccac
     5941 tttttcccac aagagcccgt cgcagctggt cattaagttc ctgcagaagt ttcgctgtta
     6001 gcgctgtttt gacatcacga atatttttga aatggttata cagcgaggga gccttgatat
     6061 ccaagcgttt ggctaaatgc tgaaaggtta tttgctgaac atccatctct tctgctagtt
     6121 ctcgaaagca gtcgatgatt ttctcttgag acagatttct ttttttcatt tccatgtttc
     6181 ctctcataaa ataaatcctt cactctttca gtttaccacg aaaaagaaag agaaaaaaga
     6241 gactttcatt gataaactac atattgtagt ttataataaa gagctgtaga tgaaaatttt
     6301 cagaaagaag gagtctaatt ggctgcaaga ataaaggaaa aattatttag gaaaagagaa
     6361 acttgggaac aaaacttgtt tgtcttatgg tttggaacat ttatggctgg tatcggattt
     6421 agtttagtca tgccttttat gtcactttac atagatacgt taggtaatta tagtacgtca
     6481 caattgaact tttggagcgg attgactttt tcatctactt tcttggtgac tacgcttatc
     6541 tctccttggt ggggaaaatt agccgaccaa aaaggaagaa aattgatgct gttgcgtgct
     6601 tcattaggaa tggcaatcgt catttctttg atgggttgcg tgactagtgt gtatcaatta
     6661 gtcgcattgc gtctgcttca agggattttt tctggttata tcagtaatgc cactgccctt
     6721 gtcgcaactg ggacgccaaa agaaaaaagt ggtcaagttc ttggaacctt agcaactggt
     6781 tctgttacag gaacattact tggaccgctt cttggcggga tctctgcttc agcgtttggc
     6841 tatcgcccta cctttttcat tacagggatc atcttatttt tcgtcttctt gttgagtctg
     6901 tttttcgtcc atgaaaaatt tgtcccagtg aaaaaagaaa acatggtttc tgccaaacag
     6961 attttcaaag acttgaaata tccacacgtc gtcatcggta tgttcgtcac aacgatgatc
     7021 atccaagcat ccaacaattc cattagtcca atcatcagtc tgtacattcg ccaattgctg
     7081 catggacatg ggaatgttac gttgatcagc ggaatcattg cttcgatacc tgggattgcc
     7141 actttgatag ccgctccaag atttggtcgc ttaggtgaca agattgggag tgaaagaata
     7201 cttgcgattg gtttgggttt tgcgattctg gtttatatcc caatggcatt cgtcacgaat
     7261 gtttggcaat tagctgcctt acgttttttg attggtatct ctgatgcttg tctgctccct
     7321 gctgtccaag cattgatcac aaaatattcg cctcatcaag ctgctggacg gatcttcagt
     7381 tataaccaat ctttccaagc aactggtaac gtagtagggc ctatgatcgg ctccagtgtt
     7441 tccagtgcat ttggttatcg cggcgtcttt ctttcgactt ctcttcttgt tttggtcaac
     7501 ttcttgcttg tacgacacaa tacacaagag atccatcagc aagaaactgc agaagaaaaa
     7561 gcttcaggag tctccatagc ttcagggcac tctccttctc atagacaata agcgtaaatg
     7621 aaaaacactg cttgaacagt tgtcacagac tgtccttgca gtgtttttgt ttaggcctgt
     7681 tttttcaaga actcagataa gaggaataat cccttttcca aggtttcttt tttacaacag
     7741 taacctagtc gggcatgctt cggtaaatca aaggcacttc ctggtactaa tagtactcct
     7801 gtttcttcta ataaattgat acaaaatgtc tggtcatctt cttcgatggc taatttaatg
     7861 aaagaagtag agacgtaatt gggagcgaca agttcaactt tcggttcatt ggctacccat
     7921 tgttttaaaa tcacaaggtt ctctgtaatg atctttttgt ttcgcgccaa tattttttct
     7981 ttattcttca atgcatgtac agcaagatca tctgacagga ctccgccgca aatcatcgtg
     8041 tagtctcgat actttcgaaa aacttctgcc aactcaggtc cagtagctgt ccagccaata
     8101 cgaatacctg gaatggagta ggttttggat agggaattgg ttgctatacc tttttcatag
     8161 acatctacga tcgacaagaa ttcaccttta tccgttaaag gcgcatatac ttcatctatc
     8221 aatacatatg catctactgt acgagcaatt tctgcgattt tttctaaagt tttccgatct
     8281 agcaatgtgc ctgtaggatt gtttgcacta ttcaaacaga tgatttttgt ttcaggtttg
     8341 actaaggctt ctagctgttc taaatcaaac tgccaatctt cttcttcctt caaatgaaca
     8401 aagtcaacag cggcacctaa agatttgggg atgtcatata attgctgata agtaggaagc
     8461 atcgaaacaa catggtctcc tgcttccact aacgcgtata gagctaaaag attagcacca
     8521 gtcgctccat tcgtttgtaa gatgttttcc ggatcgacgg tttgataaag agaagcgact
     8581 tcttgtttga aaacatctga tccttcgatc cagccatagt ccaatggttc gtttttgcgt
     8641 ttttcgaaaa atttacttac gctagtccca tctaagccaa cgagttcgtc taatgtcaat
     8701 gcttcgatcg agctttgtgc aatatcatat accgctttct tttcccattt atttagccat
     8761 tcttctacac cgaaatttgc gattttcatg tttctttccc ccttatatct tgatccagcc
     8821 tacagcaagc aacccgattg aaagcagtgc ggccacacaa atcagcccaa tcattacttt
     8881 ttcttttccc gtaatttgat gtttggtttc acgacaagcg atccagtaga agcaaaaacc
     8941 aggaagatag gcaatactac ataaaaggac ataagaaaat cctgctaaaa tgatgcccat
     9001 caattcaaaa actacagcaa tcccaccgat cactacttgt tttttgattc cttcttttaa
     9061 agaaaactgg acttgataga tcccgacaag tagataacaa atcaaaattg ccgctgtaca
     9121 taaagaatag gcaaattgat aggcataatc agtaattaag aaagtcaata agaatagatt
     9181 agtcaagatt gcagtaacaa ctaacgaata agttggggca ttttttttat tcgtttttcc
     9241 ccaacctttc ggcaacagac cgtctcgagc catcaacatc gttgtttctg ctgggagcat
     9301 cgtccaagac aaccaagaac caatgatcga aataatcaag ccgatattga tcagcgctgc
     9361 tccccaattt cccacgattc cttttaaaat atttgccata gcaggttgtg aaatagttgc
     9421 taactcttct tgagataaga cgccgtatgg caagatcgaa gcaaggatat agataaacaa
     9481 taaacaaagc agaccaatga tcgatgcttg ctgggcttct gaacgtttct tcgcgcggtt
     9541 ggctaaaaca cttgcgcctt cgatccctac aaagacccac atcataacca tcaaacaacc
     9601 tttaatctgc aaccagatcg ttccttgctg ccctgttcca ttcactagat tatcagatac
     9661 gttaccccaa aaatcagcag tgaatatatt cactttaaat gcgataaata caaatattaa
     9721 aaataggaat aatggcacta atttacagat cgtcacgatt gtattgatga cgctcgctcc
     9781 ttcaactcca ttgtttacta ataaagtcag accccaaata aaaatacttg caaataaaat
     9841 agaaggaaca ttttgtccac ctttgaatat cgggaaaaat tctcccatgg cgctcatcag
     9901 catcgttgca aaagcaacat ttcccagcca cgcagacaac cagtaacccc aaccactgat
     9961 gaagccacct aatttaccaa atgaagcttc cgcgtaaccg aaaataccac catctagatc
    10021 tggacgcttt tctcctaaat gattcagcga taataccaaa gctaaaatac caatcccaac
    10081 gattatccat gaaaggatcg ctggccctgg agctgcagaa ctagccagat cacttgtgat
    10141 cccaaacaca ccgcttccga ttgacgaact gacaaccaga gcaaccagtc cccatttgct
    10201 aatacccgtc gatttctttt ccatttccat caccctcact tataaaattg aacaaatcac
    10261 ttgcaaaaga ttcccttcta ttttgcaact gctcttgctt aacaaaaagc aactttattc
    10321 atattattgg atattatgaa ctttttacac aagtatttca agtataaaat gaataaaaat
    10381 taattttatt gcaaaaaaac agctatgcta tccaaaagaa aaggtgtttc ttttgttagc
    10441 catagctgtt ttgattcatt taatatcgct taaacgtatt gtaaaacttt tgtttcttga
    10501 tatgcgtggt cgatcaaacc accacccaga cattccattc catcataaaa tacaactgct
    10561 tgtccaggag tgattgcacg tacaggttcg tcgaatacga cttctgcacg attatcatcc
    10621 aataagcgaa ctgtcacagg aacgtcttgc tgacgataac ggaatttcgc tgtacacttg
    10681 aattcttttg gcattggttc attcgtcgta aagtggattt cacttgcatc caagcttgtg
    10741 gcatacaatg caggatgatg gaacccttgc cccacatata atgtgtttgt cgctagatct
    10801 tttcctacaa caaaccaggg ttcttgcgaa tctcctccgc caccgatccc tagtccttga
    10861 cgttgaccaa tcgtataata catcaagcca gcatgttgtc ctttgacttc accatcaaga
    10921 gtgaccatat ttcctttttt tgctggcaga tagttgctca aaaattgttt gaagttcttt
    10981 tcaccaataa agcagattcc cgttgaatct tttttcttag cagtcgcaag gcctgcgcgt
    11041 tcagcaattg cccgtacttc tgatttttcc atgccgccta gagggaacat cgtttttgaa
    11101 agctgttctt gtgataattg gctaaggaag taagtttgat ctttattatt gtctactcca
    11161 cgaagcatgt ggaccacgcc gttttcatcg cgagtgactt gcgcataatg tccagtagct
    11221 acataatcgg cgccaagatc cattgcataa tccaagaatg ctttgaattt gatttctttg
    11281 ttgcacatca cgtctgggtt aggtgtacgt cctgcgcggt attcggctag gaaatattca
    11341 aatacacgat cccaatattc tttttcaaaa ttcacagagt aataaggaat cccgatttga
    11401 gcagctactt tcgctacatc cttataatct tccgtggccg tgcatacacc gttttcgtcc
    11461 gtgtcatccc aatttttcat gaatattccg atcacgtcgt atccttgttc ctttaacaaa
    11521 agtgctgtta cagatgagtc gacaccgccg ctcatcccta cgacaacgcg tgttttgctg
    11581 ttgtctgtca tgatatcacc atcatttcaa ttagattctg aaacatctac gagttgaagg
    11641 tcgcaacttt tcagtatttt acattatacg tcatatttct gaaaatttca tcccttaatt
    11701 atcaagtcgt aaaaatactg ttctactgga cctattcagt acacaaacat gatagtcaac
    11761 caaaaaatca ctcatctttt gagcattcga tataaaaaat tggcatactc ataaaaaggg
    11821 ccagcctttc ggcaataagg aataatttta taaattgtga aaaactattt ttcaaaattg
    11881 cttcttatcg cttaaagctg cacgtctcat ttacaacctt ttctttttag atgttatgag
    11941 ttgctcagat aagtgatttt gtttactcta agaaaaaagg gaggcaaaag atacatgaat
    12001 tactttatca gtgatatgca ctttttccat gaacgcttat taggaaaaaa cgactttgct
    12061 ccgcggctct ttgcaaatgt ggatgaaatg aaccaacagt tgatcactag ctggaatgca
    12121 gtaataaaag aaaccgacca tgtttatcat ctaggcgacc ttgctatgca tccgcaatat
    12181 gaaaaagcaa atgcagaaat tttggaactg gtcactcaac tgcaaggaac aatccacttg
    12241 atcaaaggga accatgacag tcgcgctttt ttccgttatt tagaaaaaaa tgatcctagg
    12301 cttactgacg gaagtcccaa attttatttt tatgatgtag gtgccatcgt taaattcgac
    12361 catcaacaat attacttgac tcattatccg atgttgctcg ggcctaacga cactatccgc
    12421 aatcttcatg gacatatcca tcattacagc gtacctatcg agaacgatgt caatgtaggc
    12481 gtagacgcac cggaaagaga actcttaaag gaaaaactac catttggcac tccgttatct
    12541 gagcaacaaa tcaaagaaat ctatgaagca aagaggaagt acgataggtc gtgaaaaaac
    12601 tgccctatat caagtattaa acaaataaag ataattactc atatttttca tttgagtagg
    12661 cttattgcca caggaacatt aggatcagaa atggagttgt aacaagactt ctgtcacaac
    12721 tccattccat actattcgtc tttttgctca tggtgttctt ttaccagttt tttctgtaat
    12781 tctttatcat aatttcgggc agctgacgtt aaaaataaaa cgattccgca taataaaatc
    12841 ccgattccgg aaaacaagaa cattttttct acccctaaac gatcagctaa tggtcctgca
    12901 aataataatc caattggacc tgccaggttc atcaaagagt tgaagttccc taagacacga
    12961 cctaaaacat tcgattcata actctgctgg atcattgcca tcagcagtgt attgaaatat
    13021 ggcgttgcac aacctgctcc tgcattcaag ataagaaagt acaagaaccc ttgactatcg
    13081 tttggaacca atccgcttgc accgatcgtc aggcccataa tgatgtaggc tataataata
    13141 ggtttcattc ggtctttcca tgttcctata aaactgatca gtgcaccgcc taagagcatt
    13201 ccgactgcgt agactacttc cactgctccc gcctgtccaa cggaaccacc aaagtaatct
    13261 agcgtcatca atggatacag actgattgct ggcatgaaca acagcatcac aaatgcacca
    13321 ttgatcgtta tgtaccataa ccctttatta tccatcaatt gctgcagccc aaattttgca
    13381 tctttaaaaa tagtaagcgg aacttccaat atttcaggag aaacttttgg gatcttcaca
    13441 aaaatcaata agccgacacc aaaaactgcc cccaatacat ctaataaaat aaggtaattg
    13501 acaggaacga ctgaaaacaa agccgcacct agagctggcg caatgatgaa attcgctgat
    13561 tggaccattc ctaactgtcc attcgtcctt gttatgtgag aagatggaac gattgtcggc
    13621 ataatcgact ggatcgttgg catttggaat gtttgtgcga ccgaacgcat aaacaaagac
    13681 acaaaaacta gccaaatcgg gaaggattct gaaatcgttc cgactactgc taaaataagc
    13741 gcgaaaatcg ctacaataat atccgtgaca atcaaaagag cttttttatc ccagcgatcc
    13801 actagcggtc ctacaaatgg gcttagtaaa accatgggaa tcattcctag taaagtagca
    13861 aaactcaaaa ttgtcgccga accggtttct cttgtcaaat accagatgat cgcatattgg
    13921 acgaccatac tagtgattcc tgacaaaaac tgtcccgata aaaagaacaa ataatttctc
    13981 ttccaattcg ttaaaacgac cgactgttca ttttccataa acatccctct tttctttttc
    14041 attttgtata gcgtttgcac aacaatcatt atacgggatt cttttttcaa aaaatacctt
    14101 tttccctaaa taacaatcgt ttcaatttaa atttctttac ttagaaacaa taaatcagca
    14161 aaatattaaa aataacaaca tgtgttaaat ttaaaaataa aaaagacaac taatttgcgt
    14221 cgtccttaca aagttagtca tctaacaata ggccgtttca aaactagttg tctttttata
    14281 tccacagatc attcgacttt ttcgaataac ccacggctaa tcatcccatc catcagaaaa
    14341 taaaatttat cttggctcat tttctgtttt ggatctttga aaatattgac tgctttcaat
    14401 ccatttgctg tagtgatcga cattttcaat gtttgaatat cttttgatac agtgattttt
    14461 aatttgaatc cttctttgct ttgcggcgtg gcatctaatg gtcggatcaa ttgataattg
    14521 cctccgtttg tttctgtaaa tccattatcg cgcaatgtat atctttttgc atcaggatgc
    14581 aaacgatagc taattggtgc gcccagtacc gttgctgttg tttcaaatgc catgattttc
    14641 acctcgataa aattagtttc tctttattat aaaagtttat cctgattttt actaggtttt
    14701 tcagttaagt tccctaaaaa atgaaggcgt tctctcagac atctgttcat ataagaatga
    14761 cttcactagt tattttttga cagcacgaac taattgatca aggaaatact ggatgtcgtc
    14821 ttcggtattt cccaaaccaa agctgatacg gatggattct tttagtatcg gtgtatcttc
    14881 tccatacatt gcttctaata cgtgtgaagg ctcgatattt cctgctgtac aagctgaacc
    14941 agtagaaata gcgaccccat taagatcaag cttcatcagt agcaaatcat ttgcttcgcc
    15001 aattaagcga agattcaaca catgagggag tttattcgtt aaatcaccat ttacttgata
    15061 agggatttcg tttgcttcta atgtatcaag aatcaattgc tggaatcctt tatatttgtt
    15121 gttacgtgct tcacgttctt caggtgacag cagttcaact gcttttgcca taccccagat
    15181 ccctgctaaa ttttctgtac ctgcacgccg cttttcttcc tgctccccgc ctaaaagcaa
    15241 tgcagggata tttactccgt ctcgtttata taagaaaccg acgccttttg gcccattgat
    15301 tttatgagca gagatactta ataaatcgat tcctaattct tctggatgga tcgtttggtt
    15361 tccgtacgct tgtaccgcat ctgtatggaa ataagctgga tgatccgcta aaagttcacc
    15421 gatttctttg attggcatca aatttccgat ttcattgttc ccgtacatca cagagaccaa
    15481 gatcgtatct tctcgtaacg cttttttgac ctcttcgatc gacagattcc ctttttcatc
    15541 tacaggcaga tatgtaacgt caaacccctt tgtctctaaa tatttcatgg tattaagaac
    15601 agcaggatgt tcgatagctg tagtgattag atgtctgcct tctttttgac gcgaaaacgc
    15661 tgtttctaag atagctgtat tatccccttc tgttccccca ctgttaaaga tgatctcgtg
    15721 aggttttgct tgcagactgt ctgcaatgat ttgtcttgct gtttccaatt tttcatgcgc
    15781 gtggcgacca aatccatgta tgcttgaagg atttccaaac gtgtcttgca tgattgccgt
    15841 catcgcttca attacttgtg gatgcatggg ggtagttgcc gcatgatcca gataaatagt
    15901 tttcacttca ttcatccctt ccaaattatt gctaggcaca ttctagcata aaatagcgaa
    15961 caaaccaaag aagagctcat ttttgtctag aggacgtttc atgggcatag aaaaaaggag
    16021 ctgtgacaaa agtcttgtcg cagctccttg aagctgctca cttctgtcac aacttctttc
    16081 cctctttttt ttgtttattc gaattctttt tcttccagac ggaataacgg actcatcggt
    16141 gtattttcat ggatgcgttt gaccgcttca cccattaatt ctgaacatgt aacgattgtt
    16201 aagttttctg gatgacgatt ttcttctgtg aaaacagaat cagtgataca aatatctttg
    16261 attggtgcat tgtctaaaat acttttcgca tgatcggaca ataatccatg tgacgcacag
    16321 gcatatactt cttttgcgcc gttttctttt aatacatttg ctgctcgtgc aagcgttgct
    16381 cctgtgttca agatatcatc taccatgata catgtctttc cttgaacatc accgatcaca
    16441 taaccaccct cagttgaagc atcatctgca tgatctacga tggctaatgt gctgttcaaa
    16501 tattctgaaa gactacgtgc acgctgaaca ccgctgtttt ttggcgaaac aactacgatg
    16561 tcatctcccg tcagacctaa ttgacggtaa taatgagcaa acaacggcat cgtaaataaa
    16621 ttatctacag gaatatcaaa gaatccttgt acttgaaccg tgtgcagatc taaagtcagt
    16681 actcgagttg cccctgcttc ttcgatcaag ttagcgatca atttcgcagt gatcggttca
    16741 tgaggtttcg ccgtgcggtc ttgcctagca tacccatagt aaggcaatac gacattgatc
    16801 gttttcgcac ttgctcgctt cattgcatcg atcatgatca gtagttccat atagtaatca
    16861 ttgacaggtg cattcgttga ttgaacgata tacacatgat cccctcgaat actttcttcg
    16921 atattgatgg aaatctcgcc atcactaaat tgcttcacga cgcttttacc taattctgtt
    16981 ccgaacactt tcgcgatttt ttcagctaat ggacggttgc cattcaaact aaaaatcttc
    17041 aacgtgtcat cctgatactt attactcatg tagtcctccc caaaacttct ctattcttcg
    17101 atagtttaac atatttttcc aagattttct gttaatttca gcaaattctt aaggaagtga
    17161 aactgttccg ttactccaac tggcaggaat gactttatga taatcgcccc agttgtcgtg
    17221 tactttgtaa taacgttctc ctgtttcagt ttcaaaataa gcgtacgctg tcacccaatg
    17281 attgccatat gtactgccaa gtactttcaa aataccaatc atcacaggtt tgccttcacg
    17341 tatacgtttt gtagctcgct gccatgaacc tagaagagtt gctcgtgcac gctcatgatt
    17401 gccattcttc tttaaaaaac tagaaatccc tgtactaacc tgaaaaggaa tcgtaggaag
    17461 tcctagtggt tggatctggc tacgcaatgc cttcgtcaaa accaacgaat cagccgtatt
    17521 tttcttgcga atctcatttg gaagcatcca ccccttacga tagtcttgat aataggcaag
    17581 gagaactgct gccgcgtaag taccacaaag atagcctgag ggggtagccc atttcttata
    17641 cctcaaaaaa cgttcttctg gcaatcccac ccagcaattt gcgagttcct ttcctgacct
    17701 tttttcttcg atcaaaacgg gaatatcttc ttttctgttg atccatctag ataactcgat
    17761 tggctcttca ttgatcagct tccatttttt acaagaaaga ccctcttgat aagtatattt
    17821 tgctggagaa tattctaccg gatgtcctga ttgatcgata atcacataac tttgatcttc
    17881 aaaaaccaga gctaaaaaaa gcaatttact ttttcttgac tgcagctgct gagtgctggc
    17941 taatttttta atttttttat ctactttgaa atataaaggt ttatccacta cttgattcag
    18001 ttgggatcgc ctcctttttt tcattataag tgaaggattg aaaaaaacaa atcagtttga
    18061 ttgttcgaat tttcaatttt ttatgttcta tttgttaatt ccttcatttt gtaagataat
    18121 gggcacacga aacaaaaaag gagcgatcga tgaatgaaca aagaacgatt gaaacaagat
    18181 ttctatgaag cagtcaatga agaatggcaa aaaacagcaa aaatccctgc agataaacca
    18241 gctacaggcg gtttccaaga tttagttgac gggatcgacc aacttttgat gggagaaaca
    18301 gacgatctgc ttgcccatcc agaaaaagtg tcttcagaaa aaatgaaaca tttccttgca
    18361 tattatcaac tggcaaacga ttatgaccga agaaatgagt tgcatgctca accgcttcaa
    18421 cctataatcg aaaaagttga atcattgcag tctttcgacg aattgaataa gcaatttcca
    18481 gaatggctgt tggatacatt accattgcca tttaatctgg atgtagatgc agatatgaag
    18541 aatgcgcaaa cgaacgcctt ctttgcttat ccgccttctt tattccttcc agataagacg
    18601 tattatgcat cagaccatcc caacggtgca caactaatag gcgttttctt tgatatggct
    18661 gttcagttat tagagcttgc cggcaaagaa aaaagtcagg cagaagcaat cacggaacaa
    18721 gcagtgcaat ttgataaatt gattgctcct catgtaaaaa gtgcagaaga aaacgcagat
    18781 tacagcaaaa tgtataatcc gcaatctttt gatacattta ttaaatacac agataaactg
    18841 gacttgaaaa aacttgtcac gggtttgatt gggacaactc cagataaagt gatcgtaact
    18901 gatccagtgt acttcgatca tttgaatgac atcctgacag aagctcattt tccgttattc
    18961 aaaagctgga tgatcattaa aacagtacgt tctcttagtg gttatctatc agaagaattc
    19021 cgccaagtca gcggaatcta ttctcgcgta ttgtctggaa cagacgaagc aatgcctcag
    19081 aaaaaagcag cgtattacct tgcctctgga caattcgatc aagtagttgg cgattactac
    19141 ggaaaaaaat attttggcga agctgctaaa aaagacgtag aacaaatggt gaaaaaaatg
    19201 atcgccgttt ataaaaaacg tctagaagaa aatgactggc ttggggatgc aacaaaagaa
    19261 aaagccgtca taaaattaaa taacttaggt atccaagtag gctaccccga taagatccca
    19321 gcattattcg accagttcaa aacagtacct gcagatcagg gtggtacttt gctttcaaat
    19381 actcttgttt tcagcaaact cacattaaaa gatcgtttca gcaaatggaa caaaccagtg
    19441 gatcgttcag aatgggaaat gagtgctgac acggtcaatg cttattatca tccatttcgg
    19501 aatgtgatcg tctttccggc agcgatcctt caagcaccat tttacagtct agaacaatca
    19561 agctctgcta attatggtgg aatcggagct gttatcgctc atgagatttc ccatgcattt
    19621 gataataacg gcgctttatt tgacgaatat ggcaacttga acaactggtg gacagaagaa
    19681 gatcttacac aatttcaaaa caaagcacaa gcaatgatcg aagaattcga tggtctgcct
    19741 tttgctgacg gaaaagtaaa cggaaaatta accgtttcgg aaaatattgc tgatgcaggc
    19801 ggtctaagct gtgcattgga agcagcaaaa acggaatcag atctttctat cgaggaattc
    19861 tttgtcaatt gggcaacgat ttggcgtaca aaagcaaaaa aagaatacca acaactttta
    19921 ctgcaaatcg atgtccatgc ccctgctaaa ctccgagcaa acgtgcaacc aaaaaacctt
    19981 gacgaattct atgaaacatt tggtatcacg gaacaagacg ctatgtatct agcgccagaa
    20041 aaaagagtgc gaatctggta agaggttgtg ccagaagtgg tcagcttcaa gaaataagaa
    20101 ggaatttggg aaaatcgctt ctcaaatttt tgtgacattt cggcttattt ttcgaagaag
    20161 ttacttctgg aataccatgt attagaggtt gtgaaaaagc tgcttagttt caagtagtaa
    20221 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttgactta ctaccgagaa
    20281 actggctttt gaacaccgtt tatcgagagg ttgtgaaatc agcgtcctga cctgagtatt
    20341 agagaaaaaa acggaaaaat agttcctcat attttgccgt ttgttgagct aataccgagg
    20401 gtcagctgat tgaacaccgt ttagtggaga gattgtgaaa aagctgtcct gcatcaagta
    20461 ataagaacag ccaatcaaaa gcagcaagga gaacctcatc tataaaaaga tagaaggaag
    20521 tgagacatct attggtctca tttccttcta tttttacttt cctcagtcaa ttgttttaca
    20581 tcataaaagg agaaattcca cttatttttt tcgctgtttc atgacataaa caactacacc
    20641 gattaacaaa attcctccag ctaatgctag caacgggtta ttaaattctc ccgtttttgg
    20701 gagtccttga gtgccatttt tttcactttc ttttgctgtc ctatccggat gagaaggttt
    20761 tccatttggt tttccatttg gtgattcatt tcctggattt tctctttctg gtttgtcatt
    20821 tcccgggggc acatcggcag tttctcgcac agtgatcgct ttttgctggg taacagattc
    20881 tgtatgagca gaccattttt ccccatcaaa tatttccgaa cgataagtga cttctagcgt
    20941 atattctcct tttgaaggtg ctgaaaaaat agcggtatga ttagaaaatt gagcacttga
    21001 ctgtgtttca acgatttgga tcttttctgg gaaataacgc atatcttcaa agacaggcgt
    21061 tccttgattt ggtgtgaaag ttgacacaaa aactgtaaaa ggcttcagtt caatgatatt
    21121 tccttctgca ttctccgcca caccatttgc ttcttgtata ataatcggat tattttgttc
    21181 atttggtttt gtctgatttg gttcttgtac gattgcatac tctggatatt ccgaagacgg
    21241 tgaggtttct ccgtcaaaaa tagcacctac agataatgga agaccatcca ctctttcctt
    21301 ttctgtttga cgattccccg gtttaatctg catcagtcca tgaacatgga tacttccatt
    21361 ttcatagcgc gtaacaggct gctgaccttc tttcgaacat gtatttagag actcgatcca
    21421 atcttttgat atggtatgtc caagagtatt ttctgattgt ttctctcgtt cattccaata
    21481 gtagttcaac gagtggtaga tttgatcttc gttttgattc aatgggcgga tctgctctct
    21541 catctcaaga ttctctgttc ggaaagataa gataccagaa gcatggtagt ctgtgtttcc
    21601 tgctgaagag gtataaagag ccacattata tgaaccgtta ttaaaacttg tactgctatt
    21661 gacgataata tctgttccgc tattggaatc gattcctttc gcaagatttt cgaaagacaa
    21721 actattgatc aattcatgag ggcccgttaa agaagaaccg cccattttga atccattacc
    21781 gttaccttct ccctcaattc ctggtaccca gccgtttcga taagcaactg agtttttgat
    21841 gattactttt ccgatcgaac ctgtttcatt tttagcaaaa aggtcccaac cgtcatctgc
    21901 attatgatac gcgatacaac cgtcaaatac atttccttct cctattgtca gtttggccgc
    21961 aaatccatcg gcatcttcaa atcctggatc ggcattttca aaagatgtac agttcttgac
    22021 taagttatgc gcgggccatg cttcgaaagg atcatttgag ctaccgctga tttggattcc
    22081 tgtatttcca ttccgataag catgaatctc ttcgatcaaa ttatgatttc cagaaatctg
    22141 taatcctttt tgcatagctg cactatttgt aatgtcaaac cctcgtaaac cccagtagtg
    22201 actgaacagt gtcatcccat ttccagttcc tttaaaatca agtacaggac gcttgttttc
    22261 tggatttttc tctgcaatca actgaatcgg gttttctctt gtcccgttaa cgccttttgg
    22321 aatcgtcaat cctctttcga aggaataagt tccaggcgcc atgacgattg tctgcccagc
    22381 atatgcgtat ctcaatgctt gtgtcagaga taatggattt tgtctgcttc cgtttcctgc
    22441 atctgaccct tctggtgtta cataaactgt cgaatattta ggtttacggt agtccactgt
    22501 atgaagaatc tcttttgttt cataactagt catctctacg tattcttctg gcggatagtt
    22561 tttatctggc gtaaaactga aagtaaattc gttcgttcct tccatcagtt ttgtctgata
    22621 atcaaattcc cgattcgcag tgatagccaa gttttttgcg ttcttaagca cctctcctgt
    22681 tgctttattt ttaattgtca ataatccgtc agcatttgct ctaaaggaca tagtatgatc
    22741 ttggtttcct gaatgattac tagaggtcac agtgtaaatc ggatcaatca agcgagtagg
    22801 tctttcttgc ccaggaggat ctgtcgcagg atctgagtaa gcaacttcga ttccttctac
    22861 cttgatcgtc atattccttg ctgcagcaaa tcctgcataa ataaccgatt catctgaagc
    22921 gtataatttt tcccagtcat acatgatgtc agaagccatt tcttctcctg tttcaggatc
    22981 gtaataatat gcctctaaac cagtattcgt ttttttcatc tctacgtcca gtttagtaat
    23041 cgagttcgtg gccggaaaca gattcccatg accgtttccg aatatattat aagaacctgt
    23101 ttctttttcc aagaaccctg ctgaagtctc taaaggtgtt gtttccactg agacactccc
    23161 aggagctggc gcagcttgcg gatcttcaga tgatattcct gtgattgccc gtgtccccaa
    23221 tccaagtcgc atcgtatatt tgctgccgct cgtgttgacc acttcttgtc tatccgagtc
    23281 ccagacatat tcgatccgac tgcctagtat ggcaaatgaa tttgaataaa atgcctgccc
    23341 aaacaaatga ttttttggta ctgcgtctct taccattaaa gcaaatcctt cttgggcatt
    23401 cgtataggtc caagattcta tttcgatcgt cgcccgcatc ctaaagttga tgtctttggg
    23461 gattgcttga taataatagg tcattccatc tgatccgctt gactggaatt ttccgccgtt
    23521 attcgtggaa gagagccgca cgccgtcttc taatggttca atggcatacc tactagcact
    23581 tgtgctttct ccgaaaacaa cccctttcca ctcttcattt gcttcttcag attgcttttt
    23641 tgtcttttca ttttctgatt ctttcatcat aggatcattt ccttcttccg tatccatatc
    23701 ttcactagtt cttggtattt cctccattgt tgacatccct tcaatgttca cgtgtgcatt
    23761 ttcttcgttc acagactgtt gttcgttagc agcaacttca acgacagaaa ttaaaaccgg
    23821 ggtactgagc ataaggagat tcatcattag cgcactgtat tttatacgtt tttttaacaa
    23881 gtgtattcct cccgtaacaa attagaaagc gtttacttaa agtattacct aatttatttt
    23941 tactgtcaat aaaaaacaaa attataataa gtgtatttta taaaaagaaa aaatataact
    24001 taagttgttg ataataaaga gatttattaa cggaaaaaga ataagttttt ttaaaataac
    24061 gtataaaaaa gagcataaaa caaagtcgtt tgttttatgc tcttctttta ttattttgtg
    24121 ctttttattt tatcaaatca ctttgttttt ttataaaatt tctgcgccta gtgtggactc
    24181 aaaatgtctc aatgcccatt catgtccaac gggatcgaaa cttgccacgg aatctttgaa
    24241 aatatggagt ttgtatccta gattatacgc atcgactgct gtatgcaaca cacagatatc
    24301 tgtacatacg ccggtcaaat aaatatctgt gatctggcgt tctcgcaaac ggatgtctag
    24361 atctgttcca ctaaaagcgg aataatgccg tttgtctatc caataaacat tttcctcttg
    24421 ctcatagtct tggtataaac tttttaaaga gccgtacaat tcccgtccac ccgttcctat
    24481 cacattatgc ggaggaaata agcggttctc cggatgaaag gaatcttttg gatcatgcgc
    24541 atcaatggca aaaacgacaa aatccttttg atcaataaac ttctttgtat gagcagtcag
    24601 ctttttttca attacttgtc ctgctgtccc agtagtcagc tttccatcct ctgcaacaaa
    24661 atcatatgtg tagtcaatcg agatcaatgc gttcatctta gtcctcctta tacgagatgt
    24721 ttgacaaatt cgatcaccat ttctgctgat cgtttgcctg cgtcttcgat aaattcgtca
    24781 aagctttgtg tcgccgagtg atctgctgtg tcgctcattg cacgtacgat caaaaatggg
    24841 atattgaact gacgagctgt ttgtccaaca gcggctcctt ccatttcgca agctaatgct
    24901 tcagggaaat tcgttaagat ttctttgatt ttatctggcg agtcgacaaa tgtatcacct
    24961 gtaacgatca atccttcttt tgcgttcaaa ttcgttgctt ttgctgcttt aaccatttca
    25021 ctgcgcaaat atgtgcttgc ttcataatat agaggcattc ctggtaattg tcctgggttg
    25081 tagccaaatc ctgttgcatc tgcatcaaaa taagctactt tgtctgatat aacgatgtca
    25141 cctacttgta agccttcacc gattccgcca gctgaacctg tattgatcac catgttcacg
    25201 ccgtattgtt ggatcaacag acttgtggta atagatgcta agacttttcc tataccggaa
    25261 cgtacgacga tcacttcgtg gttacctaat gaacctgaaa taaataaagc gcctgcgcgt
    25321 tcccatgata atggttcgct taggttctct ctcaaaattt ttacttcttc ttccattgcg
    25381 ccgataatac cgattttcat ctttttaatt ccttctttct atataaatgc gattgctaaa
    25441 aaaaccacac ataacattag gataacaata ataagagatt tcatcaaaaa agagttccat
    25501 ttggtcgtct tttcccgttc gctgatcctt gttttcgtga ttggtttatt ctttttgctt
    25561 tctttacgat aaaagctggc aatctttttt tcttcttgct gataagctgt ttctgctttt
    25621 cgctgttttt ttaatgactc gcttgcttgt gcttgttgtc gcttgcgaag ttcgcttcgc
    25681 gtaataagcg gtcctttggc cataagccga tccctctact ttcctttggt caatagttcc
    25741 cagtattgaa tcgcataaat cgtctttgca tcacaaatca actgatcttt catcgcttgt
    25801 tgcgcctctt caagagttag atgatacaac tccagtactt cgtcttcatc ttgtgctaaa
    25861 ggattctcga ccttctctac cccttgtgca tgataaatat gaaggacttc atttgcaaaa
    25921 cctggtgaaa gatacatcga agtaagatgg ctcagcgact tcgcacgata gccagtttct
    25981 tcttctaatt ctctagctgc tgtcatttcg ggattttgtc cttctcctgg atcgattttt
    26041 ccagctggaa tctccaaaat cactttttct aaaggttttc gaaattgttt gacaagaagc
    26101 agacgatctt gttcgtcaaa agcaatgatc ccgacaccgc caggatgaaa taccagttct
    26161 ctcttcgaag ttcctccatc tggcaaacga acttcgtcta cagcaacatc aataattttt
    26221 ccgctataga tttctttgcg actgattgtt ttttcttcaa attgctcatt gttcagcata
    26281 tcttctcctg ctttctttgt aatcataact gctttttttt catttttcaa tttttctcaa
    26341 aaactcctta ttagtttacc atagataaac cttagatttt ctctaaatat agaaaatcct
    26401 tctttagtcc gatactcttt ctagtagtcc gtatgctaaa ataagtatgt aatcgaataa
    26461 cgaaaagaat tcaatactca acgataaatg acatggaggg tttattatga taaaacgaaa
    26521 ttggccgtgg cttctagcat tggtcttgct atttctcttt gtccgaaaca atagtttttc
    26581 ttttgttcta ggacttttat tgataggtgt agttttagtt ttgtggggac tctttggttc
    26641 gcgcaggaaa aagggaaaac aagaagaaat tcctgcactg actgacgaac ttgaaactca
    26701 ctatgaaaaa agcggtatga cagcgaatga aatttcattt tttcgacaaa caatgaatca
    26761 aacaaaaaat gagatcaatc aattgcaaat gaatatgcag cagacagcca aacttaaagc
    26821 aatcgatctc cgccatgatc cagtcaaagc agcgaaagct ttattcaaag aattggtgaa
    26881 agaaccaaac cgactgcatg aagcaagtca gtttctttat acgcatctgc cgaatctagt
    26941 tgatttgaca aataagtata atgagatcaa tgaccatgag atcaaaaaca aacagaccta
    27001 tgaaaaacta gaagaaagcg cgcagatcat cgaccagctg tcagctttaa tcgcacaaga
    27061 ttatcaaaaa ttcgttgctg aggatctaga tgatatcgac gtagagatat ctgttgcgaa
    27121 acagagctta aagcgtgata ataaatatga accagaacaa aaggattaac tcttttgttc
    27181 ataaaagaag actcggaaca ttcagatgat gtctggctgt ttcgagtact ttttctaaag
    27241 tagagacatt catgtaagaa tcgagaacag attcaacaag gaggaatttt ttatggatca
    27301 taaaccgact gaaacaaaag atgttacacc agttaacgat acacttgaag atttattgaa
    27361 caacccgttt tcaactccaa cagatacgct gaccacttca caacaagcgg agattgatca
    27421 gctccaagag caacagacag ctgctcgttt aattgacaaa ctaccggcgg aacgccaaga
    27481 acaagctaaa cagctagcag caaaaatcga tgctaatgat gcacagtctg tcatcagcta
    27541 cggatcggct gcccaagcaa aattaagtga attctcacaa tcgatgttga atcatgtgca
    27601 agcacaagat attggtcctg taggagattc cttaactgaa ctgatgtatc gtctccaaga
    27661 agccaatcct gacgaactgc gtgccggaga agggaacatc ttccagcgtg tcttcgggaa
    27721 ggtcaaacaa tcgatctatg aagtgacagc aaaatatcaa aagattggtg cacaaattga
    27781 caagatttca gtgaaattag ataaagaaaa agacggtctg ctaaaagata atctgatgtt
    27841 agaacagctt taccagaaaa acaaagacta ctttgatgca ctgaatattt atatcgctgc
    27901 tggagaattg aaaatggaag aacttcaaac aacgatcatt ccagaagcga tgaaaagagc
    27961 agaagaaact ggcgatcaga tggatgttca gattgccaat gattacacgc aattcctaga
    28021 tcgtctggat aaacgtacgc atgatcttcg cttagctaga cagatcacga tccagcaagc
    28081 accacaaatc cgtttgatcc aaaacacaaa tcaggccttg gctgaaaaga tccaagcatc
    28141 tatcgctaca gccattccgc tgtggaaaaa ccaagtcgtg atcgcattga ccttgcttcg
    28201 tcaaaaagat gcagtaactg ctcaacgcca agtctctgaa acaacaaacg acttattgaa
    28261 gaaaaattca gaaatgctga aaatctcagc catcgaaaca gcgaaagaaa atgaacgtgg
    28321 aatcgtggat atcgagaccc ttcaaaccac tcaaaatgat ttgatcgaaa caatccaaga
    28381 gacattgcgt atccaaaaag aaggaaaaga aaaacgtcgt catgcagaag tagagcttgg
    28441 acacatggaa gaagatctga aacaaaaact gttggattta acccaataga tcacctttcg
    28501 cttgttacta aaacaaacgc ccaacaacag tttattacaa ctgttgatgg gcgtttttct
    28561 tatctttctt ctaacttctc cattggagtc tatttctcat tcatcttgct gtgtccatag
    28621 ccatagccaa aataaatgat cagtccaata accattacga taccgaacac gatccatgtc
    28681 acagtttgca gacgaagcat caatacaata caagtcaaga tggagacgat tggcaatagc
    28741 ggaacgaatg gcactttgaa ttctccagct tttggtttgc caaacatttt tctcaacttc
    28801 agtaagccta gactaacaag catcaaatag gcgagcgcca tgatattcgt tagttccgct
    28861 aatacattca atgggaaaaa tccggcaaag aatacagctg ccacaccagc ggcataagtc
    28921 gcttttttcg gtgtacgatg cttttgatcg atttctgtca taaacttagg aagtaagcca
    28981 tccttgctga cagcaaacag taaacgagca agtgaataca tcatcgagat cgttaccgtc
    29041 agtagcgtta aaattgcccc tacagcgatc accgcgccca ctgttccatg tcctacatac
    29101 ctcattgcaa aagccactgg gtcattgact cctagttcag tatacggaac gattcctgtc
    29161 aagatcagcg tcacgatgat gtaaaggaca gtagcaatca gtatcgaacc aatgattcct
    29221 cttggcacat ctttttgcgg gtttttgact tcctcggctg ccattgcaac ggcatcaaat
    29281 cccaagaaag caaaaaacac aagagctgca ccatctagca caccggaaaa accaaaaggc
    29341 atgaatggct gccagttatc aggtttaacg aaaaatattc ctacaatgat aaacaacgcg
    29401 atgataccaa atttgacata taccatggca ttattcaaac gtaatgcttt cttggcttca
    29461 agcgacacga tgtaagtgac gaatatcact acgagcaccg caatcaagtc aatgtatgta
    29521 ccattttccg gattgtaccc gccagttaat gcttgtggaa gttcggcccc taaacttttc
    29581 aaaaaacctt gcatatagcc agaccatccg gaagcaacag aggaaaccgc tagtaaaaat
    29641 tccccgatca acaaccaccc tgtcagccag gcagcaaatt caccaaatac aacatacaga
    29701 taggcatatg gcccaccaat cactggcact cgcgaagcaa attctgcgaa acttagtcca
    29761 gacaaaatga caacgattgc agctaagaca aatgaaagtg acagtgctgg accagcattt
    29821 tgattggccg caacccctgt caccacaaat attcccgtac cgatgatcgc accaattcca
    29881 agcatgatca aatcagacgt ttttagttct tttttcatct cactcgtatg attgagattg
    29941 atctctttct tacgaaacaa atccattgaa gttcctcccc attttaggtt ggaaaacagc
    30001 gattaaactg ttttcatata ccctaaaagg ataccaccta aaatgactaa aaggcaacca
    30061 acaataacat aaatgagctc ttttttcgtt tttctttcgc caaggatgaa aatcccacct
    30121 aaagtagaga taatgatccc catttgtgaa agtgagaagc caacagctaa accaagtgat
    30181 ttgactgtta gaagcatgca gatgtttcct aagccccata ataatccaca gatcatgttt
    30241 ttccacacaa actgatcgac tttaacttta cggaaagcaa agaagcttgc gcctaagatc
    30301 attccgatac tttgaggtaa gataattgac atcgcatcca aattcgccca gttgacgatg
    30361 atggtatata caccataacc aatcgtagag aagatcaatg ctctaaaacc cttaccaaaa
    30421 tcaagcattt tattatctgt atctattttt ccttcgtcat cttgtcgggc agtcaaatac
    30481 gcaccgctta caagaagagc taaagcaata ataccgtata cataatcttt cgtttgtgtc
    30541 cattcatgga agaaaacggc tcccgcaatc gtattcaaaa ttaattgaaa accagtagac
    30601 aatggtagcc ctacagaaac acccatgtac ttcattccat ggaactgtcc attttgtcca
    30661 acactccaag ctaagccgga taaaaatccg atcaagaaaa tccaaggggt gattacagga
    30721 ctaacaacga aaaagacaac taaagaaaac agaaatgcac cgatcgtcat tcctagtgtt
    30781 tgttgattgg catcgccacc aattttacca cttactaaac caatactacc ccatgccaac
    30841 atagggacta atgctattaa aatttccata accaatctcc ttttatttca catgataaga
    30901 aacttatcag cgaaaacgtt aacaacacaa gcactttttt tcgtttctaa cgattttcta
    30961 acgtttttca ttataaaaat ttaagattgg gaaaaataaa gtcattgttg tcccttttcc
    31021 ttcagttgat tcagccgtca aatggatacc taatttttcg gccagatttt ttgctaaata
    31081 aagtcctaat cctgttgaat gtgttttgct aagtcgacca tttctcccag taaatccctt
    31141 atcaaagatc cgtttcaagt cttccgctgg gataccgatc cctgaatctt taactgaaag
    31201 gctgactcct tgcgcttcct tttctatgct cacaatgatg tttccgtgat ccggcgtata
    31261 tttgatggca ttactaagca attggttgaa gataaaagcg atccatttag catcggtcaa
    31321 aacagtatga tcctcaccaa cgatctcgta gcgaatattt ttttggataa aataatttgc
    31381 ctgactgcgt atcacaggct gaatgattcc ttttagtcca tattcttgga tgaggtagtc
    31441 ccgcgagaaa ctgtcgagtc ttgcataata caaaacttgt tctacgtatt catcgatttt
    31501 tgataattca ttttctagta atgtatactt ttgatcgtca atatcgaact cgatcgaacg
    31561 aactagcaat ttagaagcgg aaagtggcac tttgatttca tggacccatg agtcaatata
    31621 atctttttgg tcttgttgat tactgattgc tgattgcatt acttcttggt gttcacggat
    31681 cagctgattg atatattctt ctaccagttt ttcttcttct gtcctcccac cactcaaata
    31741 attttgcaaa ggggaagttt tttgtatgtc ggctaatttt ccccaccatc ttctcttgct
    31801 caagtaacca cccagcagat aaaaaatcag aaagacgccc tcaatcaaag ctaaataagc
    31861 aattgtgctc aaatcaactt tgatgtttgg cgccagccac atcacaaaga tcgtcaatgc
    31921 aataaaaaac agccatccca agatcaatgt ccactgatct ttcaaatatt taaaaaaatt
    31981 catcttaacc gctcatcctt tcagggaacg atatatccct gtcctacttt tgtttcgata
    32041 tatccttgga tacctgcctg ttcgattttt cggcgtaacc gattgatgtt gactgtcaat
    32101 gtattgtcat ctacaaatcg ttcgtcatcc cacagtgctc gcagcaattt ttcccgactt
    32161 aagatctttc cattgtgctt catcaaaata aataatagac gatattcatt tttgctcaaa
    32221 tcaatgatct ctccgttgat ttccatactt ccgttgtcaa cattcaacgt aatgccattg
    32281 tggctcatca tttcactaga taattctgtg tagttgtaag aacggcgaag taatgcattg
    32341 atttttgcaa tcagtacatc gatttggaaa tgttttgtca caaaatcatc tgcccccatg
    32401 ttcatagcca tgatcatatc catattcgta ttcctgctgg agataaaaat gatcggtact
    32461 ttcgatactt cacgtatttt ttgacaccaa taatagccat ccaaaacggg aagattaata
    32521 tctagtaata caagctgtgg ttcttctctt tcaaagtctg agaacacttg attgaaatcg
    32581 gtcgttccaa aggtttcaaa ttgccatttc tcaagttcct ccatgatcaa ttgtcgaatg
    32641 atctcttcgt cttcgactac catgattttt gccataaaaa atccctccat ctttcttctt
    32701 gctactacaa tatcaaagaa gcccttgtga aacaagttgg catacctgga aaatgtcatt
    32761 ttagcaaacg ttaaaaaaaa ctggaaatat gcgatttaat cgcgtttgtc tcttccaagc
    32821 agcttaaatt tattatgtta ttcttaataa ttggtctatt atctgttatt tttctttcgt
    32881 tgtttttgtc ttttaaattt tcgataacac caataaccga aaagcgttag cactagcaat
    32941 atacctagaa ggagtataag taatcgataa agatggtatt tttttgtctg ttctatcttt
    33001 gaagagactt cttctgtaaa gggaactcgt cttcctgtca ctagtaatcg gtgagtgttc
    33061 acggtgtaag gtgtacaagt gataagtgtg actagatcct gcttttctct aattgctaat
    33121 gtatttgttt ttgttggaag gacaacaatt ttctcaacga cttcataagc gagcatccga
    33181 ccatacactt caagatagaa tcggtcatct tgctccattt cttcaagatc cgtaaagagt
    33241 tttttctcag caataccgct atgggcggta atcacggaat gtgtactctc tcctccagtt
    33301 ggaaaagagg tgccttgcag gactgtcgct cctctatcta acaaaagatc attcgtttca
    33361 tcaaataaag gcaagctaac attgattttc ggaatataga tggctccgat catatgttgt
    33421 tcgtaatatt cttttcctgg attttggaca tttctaaccg cttgctcaaa aggatctttg
    33481 acttgtccca ttcctgggat tactgatgta tgagcaagcg tctgattttt cttttcatgc
    33541 actgctaatt gttgctcatg tttttcttct ttatcgcgtt caagctgctt ttgataattc
    33601 tcgatccttc tttgatccaa ataattgctg agagcatctg ctaaaaatgg atatgtaaaa
    33661 actgcagctc cggcaagaaa catcactgcc ataaataatt gtaataaaag actgatttgg
    33721 gtttgaggtc tattacctat tttctttttc attttcttca ccttcttatt taaaaaaact
    33781 gcagcaacct ttataaaacc gattgctgca gcttattttt gttgcttata cttcagactt
    33841 cattttagat ttacggtacc agctgtacgc tccaatcatc aaacttattc cgattagtaa
    33901 gaatgccaag agcccgttcc caccagtagc aggaagtgac ccgcgtttca tattcggtac
    33961 tctttctggc cctggatttt ctactcctac gatctgaatt tcttcattat agcttccata
    34021 agagatgata aattcagtaa aggctgcctc acctgttgga agtacataac cttctggcgc
    34081 catggtctct ttcatttgat aggttccata atctaaccct tgaacctcaa agtatccatt
    34141 tccatctgcg acaaattctg ttgcttgtcc gcttgttgcc cactcaattc tatctgctcc
    34201 tgattcataa acagctaaag gcgactcccc tttataaaat attgcgtatt cagaacggtc
    34261 ttcattccac aattcgaatc ttgcatcttt aagcaattca ctgcttgatg catcatattt
    34321 ttcaaacttt cttccacctg ttgtgacttt ctctggcggc tctactcctt cttcataatc
    34381 aaattcatca tttcgtccga tttcaataac cgctgtgttg ttatggaaat catccgcttc
    34441 tagttctgtg gaaaccttca aattatacgt gatcgttaaa tctcctccac gtgcatctgc
    34501 taatctacct aaagtatcta ctttggctac tccattttct tctgtcaaaa tcgtcacgac
    34561 aaacccgttg cttactactt ctactatata atcttgtcct tttgttaaaa tcgtctcgcc
    34621 ggctcgcact tctatttcct gatcataata agttagacca actgtaggcg tatctgtgat
    34681 tttgtaattt ttgataacag cgcttccgtt ttcaaggaca gaatcgatga aataaggaat
    34741 aggtgctgtg atcgtgtaag aagccgtttt tcctctttct agatcaatat aagaaatcgt
    34801 ttcttgttct ccagcttcat taataatcgt tacttgtcta aggtcgcttt cctctacatt
    34861 catctgttta tctgcttctc tgatttcgtt tttcggatac aaatgcacat ctgtattgta
    34921 tgtgtctttc catgtagaac catcccacac gccatccacc atatcaggca tcatcactgg
    34981 catcataaca accattggag acgcgattct ggaaatatga gctggcgaat aagtttctaa
    35041 gaaaagatag actttatctc tagaagaagg tgcttcttcc gtcacttgga cggtagagaa
    35101 taccgcttct ccagcttcat tcgttgtttg tttgtcaata cttgtcagtc gatattttaa
    35161 aaaccaactt tctgtgtgcc gtttttgaat ccattcaatc gcttcggcag aattaagacc
    35221 gtcttctcgt tccggtgtta aaggattatc tcgaatcaaa tcgtaatata cttccgttac
    35281 gtcaaacaaa tcaaaatcga ctcctggaat attttcttca ccaaaatccg tagaaaccaa
    35341 tccgctattc ggtcgttctt ccggaacaga tgagaaacct tttttgtgta atgtaatcgt
    35401 cacttcactt ggtttttgtg cgacttcttc ggctttgact agttttccgt tcccgaaaat
    35461 ccctattccc gcagtaacga gtaacagtac actcattccc gtgacaatca tttttttatt
    35521 catttttttc tccccgttct ttttttatta ataaaacagc acctaacaat aaaagaattc
    35581 ctagtaaaga aatcaacgtt cttgcttcat tcgtttgcgg gaatacggac cattttcctg
    35641 attgacctgg attgcttgga ccactcggct ctttcggttt gtccgttgtt tcttttacgg
    35701 tctcgttata aacacgtggt gttgcggatt cataggcaga gactggaact ttcccggatt
    35761 ctaattcagc catctcctgt ccgttaacta ctacatattg tggttggcct tttgcatcca
    35821 cccaaaattc agggatgatg acctcgattc tcttacttgc ttcatccatc tcgtaacctt
    35881 ccacaccttt taattcttca aaataatagg tgccagaagg caagaaacgt tgtcctgtcg
    35941 taacaaggcc ctctttatcc gaaatgaatt tgcttacatt tttgtcattc aaaggatcat
    36001 tgtctgctgg tttgatccat tgatttttca agtcattagc aggagccata tctaaataat
    36061 atttcccccc ttctatcatc tgatatagag caaaaacagc accttctaat ggttttcctt
    36121 tttcagttgt tcctctttga cgtccatact tgaagaagta tggatctctt agataaccga
    36181 catttttagg atagatatga atctcttgca gttcctcggt tgattctgtc gggtgataaa
    36241 ttggcaaaat agcagcaatt gggatagctg tctgatcgat atcaacatcc aatccaactt
    36301 ctggatcaat cgattcttcg aaaatcaaat aaactgcatc ccgatcttgg tttttcttag
    36361 gtgctttgat acgtgcaatc ccgtctccta atccgccaac cgtatctttc ccagttgtta
    36421 ccgaagtccc tatttggaca agcctttctt ctgtgattag ctgacggata ttgtttctgt
    36481 tcgtttcagc gatttgctgg acgaattctt taggagtcat gttttcagca gctttttttt
    36541 catgataata atcggtcatg tcgtaaatgg caaatgtcgc tccatttagt ggcaccgtct
    36601 gtgaaatgat atctgctgtt tcccctgctt cctcagagat agccaagcca tcattttcat
    36661 ggtattcaaa ttgatcgtta taatcgatat ctcgaatcat ccgtttatgc aacacgaatt
    36721 ccacgacatc ttcccctgat tcttctgccg acatcgcatg tggaagaagg actgctgcaa
    36781 gcggtagtaa aacaagtaat tgaagcatca aacacaacag ctttttcatt accttgctcc
    36841 ctccttttta gattgtctga caaacaaacc ataggctgct cctgcaagcg ccatgaagaa
    36901 tgcagcaagc aggatataga ataatcgtcc ggatcctcct gtagcaggca acggattttc
    36961 aggatcgttc ccgacactaa gctgtaatct gattcgattt gtctccaaaa gttcatattc
    37021 taactcttgc tgtagatcag gcgtctctgc ttcttcgttt ggataatacg aaatctcaac
    37081 ttttagtgta cccgcttctt ttcctggaac tacccgatca ttttctatgt caggttcttc
    37141 tcgataacta atttctaaaa taaagtaacc tggaagtttt ctatagctgt caggtgactt
    37201 cacttccttg atccgataga ccccttccaa caagtctgaa gcattgaata gggaagaatc
    37261 gtttggatct ggtgccaagc ctccctcgat gatttcatac tctcctgcac tattttgttt
    37321 ctcaattgaa aattctgcgc cttcaagacg tcggctattc atactgtcaa ttttcaaaag
    37381 ttccaaatcg attggcgcta gttcatcttc taaggttact tgtagtacac catcgatgat
    37441 ttcatagcct tccggcaagg gagcagtttc gtcttcgatg accgtatctt caatgataaa
    37501 cttaccttct tcattcagtg caaactggaa cacttgatca gatagccgat acccatttgg
    37561 tgcgacagat tccgagacct catattcacc aatagacaga tgcagaggtt ggtcgtaatt
    37621 taaatcgaca tacttttcta ctcctacggc acgagaatag aagtatccga tcccaggcaa
    37681 acgtttcgat tcttctggtt ctaacggatt accagtgtat gctcgataca gcgggaagga
    37741 agaatccccc actttcctga tatcgaaacc tgcaccatct aatgtatggc cttcatggtc
    37801 taattttcta actcggatct cccgataatc aaacgtattg taagcagtga atgctaccca
    37861 taaacgatcc tcttcatctg ttgtatacgt gagatattgc caattttctt cacctgtttg
    37921 cttgagttgg atagtcccta tagcattatc gtaaagtcgc aagatccatg tgtcattttc
    37981 atcaggttct ttgaaacctt ctgggttctg gctctcaatg attttgtatt ctgcatagtt
    38041 ggtagtttct tcactatcct tataaacaaa tgaatctggc tctccgattg gatgaataac
    38101 tttctcacca tccacgatta catatttccc gtcttcatct actgaataga acgtgagtct
    38161 ccctttctct tcctctactt cgttcacacc agaaagccct ttcgctactg gatatccgat
    38221 ttccagtccg ttaccatctg tttcataaag ttcaaactct gcgccattga ttggcatatt
    38281 actgccttca attagtttat tgatattcat gtggattggc ttgaattcat ttcgcatttc
    38341 cagtttgaca tacaactcat catactctgt gccttctatg ttaggctctt gtacaacaga
    38401 aagcttgtga tattctcctt cataatagga attcggatct ttaccttccg gtccgccgac
    38461 tctcgaacca gatgtatatt catctacaag ctcgtagtga cctaacatct catcttcgtt
    38521 ggctgcatat tttttgattt ggaattgata cgtctcatct actaactgat aacgtggtgg
    38581 tccagcgatc tctctgatcc aaaatatgtc gctgactgct ccagtttcat ctcctaaaat
    38641 cggcatcttc gtttcaaaga tcgctattcc gtccgtggta gttttacttg tttcgattgg
    38701 ttcggcttcc ccactctctg gattttggtc atataatgca aattcgactc cagccaacgg
    38761 ctcgccattt tgacccttct tgctgacttg gaaattacgg cctttatgtt cgtaacgaat
    38821 ggaagaagat gggaaataca tccgtccagt agtgatatca ttctcataat cctccaggtt
    38881 ctgaatatag gccatattgt tcactgtgca aaaatttccg tcttgagctc ccgcatcaag
    38941 ttttacttgg tacttgatcc tgaccatttc cccttcacct aaagaaatcg gagaaaattt
    39001 ataagcttgg ttttcccgtc cgacatacgt tgtcggagtc gccactactt ctggtggggc
    39061 ttgtccatga cgttcttcat cccatatttc tggctcttgg tacttcatgc cgttttctcc
    39121 tggatctaga tggtaaaact gaatatctgc cgatctgcca gctccaaatg gtgagacatt
    39181 aaaaccagtt tcatcataaa gtgtggcttg ctggatcgtt ctcttgaagg tagaagagat
    39241 atcctccaag gctgtaacaa tgtcattctt gttgttcgca ttgtaatatc gcggtgttac
    39301 gccatcttct tctaaatcag caatattttt caatacattt cgtccaatag catctagtcg
    39361 ttgtctcccg ctaacgtttc catcgattcc taaaccaatg gagaagatac ttggcgggtt
    39421 ctcttgatac ttgtttttca gccaatgatg ataagcaact gtgttgatcg cagatgactt
    39481 ttcttgcgaa gtaggactgc cattcgtatt gttattagaa gaaccatcac caacccagtg
    39541 agtcgcttta ttatctcctt cttttacctc tccataacga tagtgtacat ttacttcatc
    39601 ttctggacgg ttaaagtcag atgcataggt aactggatga gtaaaccctg cattagaagt
    39661 attcccagaa aactcctcaa aatttctgaa caaaacgtca ttatcttcag caatcttatc
    39721 ttccatcaca gtccagttgc tccaagctcc attagtgctc gtacgataac ttgactgaat
    39781 cggtgcataa ctgaaggtcg gtgtcccatc tcccacaacg attaggattt tttctggatt
    39841 tctattttct ccgccattgt ctttatacaa tgtttcatag ccatttttaa gccctagtgt
    39901 aagcggagtt cctccgattg gtgtacgatt taatgctgta ttctcacttc ccgtcaaacg
    39961 attgatatca tttgtcaatg gaaagatgtc cgaactgatt tgctcatggt tattgatagc
    40021 tgtactatta tggtaaaaat tcaccatacc gattcgaata tccagactcg ggtcagagag
    40081 cagatcttta ctcatttcgt ttactgcctc aatcaacgca gcatttttag tttgactatt
    40141 ggtcccagcg gttaattcac tcatactcgc tgacttatct agaacaaaaa cgatatcgat
    40201 tggactgatt tcctttttct cgcccccgat gacatctaga tagacattgt aaagggttgt
    40261 tgcatcttca ggatgtagat cagatgctgt gctgcttggc agaacaggtt ctacccattt
    40321 tttgatgtac gccccgttat aatccaagta actgttttca aaattccgtt catttcccca
    40381 aagctgaacg gtttgagctg gaacgtttct atcttcttcg cctgcagttg atccattatt
    40441 agtagcatag tcgtaatttc gccagttcgc tcccccgttt gtataatcac tatcatcgat
    40501 caagttctct ccgtcatatg gcgagccttt gtctccttga tagcgttcat tgctttgtgt
    40561 ccaatttcct aacacttttg tatagtcatt cgttgtaaac ttcgggtagc gatgctgttc
    40621 gttttcaact tctccgctag gatagatata ttcatagggg tcttgcgtag ctgttggccc
    40681 aagacgctcc aaaataccgt tgaataactg gcgttgaatg cgctggagtg cttgaccgct
    40741 gggtacgatt ggttcgtcca gcttttccat ctcattttct tcgctacgtt gaatttcagc
    40801 ggaatcttct gtatcagttt cattttcttg taattcttgg ttatctattc tttcatcaac
    40861 caccacttga agaggtagtt acccttcgtt cacatcgggg atcttttctg tttcaaaaat
    40921 caatgtgccg gtttctgctt cttttgaata aacttttccg acataccatt cttgaccatc
    40981 gatcgtctcg acttttaggt cttctccatc ttcatcatag gaggatagac ctgttccacg
    41041 aacgtttttt acggtaccaa tcccggcggc tgccgcatcg attgctaaac gtattctacc
    41101 ttcattggca ctttcctttt tttcaaaagc cagatgccat tcaagggttt cttctttttc
    41161 aatatacttc ccttcaattt ttgcatagtc ctcatctaag aatacctcat cctcctttgt
    41221 ttctgttgac tcagcagcta catccagggt cgtcatatga tagactgact ggaaatatgg
    41281 tccaaatagc aaactgacag ttactaactg caaaagcttc aattttaacc ctttcacatc
    41341 cttatactcc tttcaaaaat atttgtcttc tttcacaaca atcaacaaaa caatgcccat
    41401 ctaattataa tttaatttaa ttttaatttt aaatcaaatg atatcctttt tagttaaaaa
    41461 acaccaatta tacaacattt attattaaaa ttaaattata aaattttata acgttctcat
    41521 ttaacaaaac ttaagttatt aagacaaatg aataaacaac tacgctttcc tcgaaacaaa
    41581 aaaataaagc acaaatgcgc atttacgcac tcatgcttta ttcgtacaat taattcagat
    41641 aacggcagcg cataggatgc caataacact tcctaaaata gctcctccta aaatgtcagt
    41701 aggataatgt aaaagtaaaa aaatcctcga ataagcgatc aaacaagcaa ataaaaaggc
    41761 taatattcct gcaactggac ttaattcgaa caacgcagct actgataaaa aggctagcgc
    41821 tgtatgtcct gaaggaaaag aagaagtctt cggtttactt gtgtaaagga caagccgacg
    41881 atttttttca taaggtcttt tccgtcttgt cgtttttttg ataaaaagca aaccaacaaa
    41941 aaaatagatc aaactgccga taagaatggc tagaccatat tctctagtat caggtatcaa
    42001 gactaaaaca gcagcaagga gcaaccaaat aaaaccacca ttagagatat tactgataaa
    42061 tttcaaaaaa ttgatttttc gactatccgt tttccgttgc ttggcgaact tgttgataat
    42121 actatcatcg attttagcaa tcaaacgcaa catgttattc ctccttttta agaacctttt
    42181 cttgcgtacg atggataaaa agcaggactt gaaaataaaa caagaaactg aaacctaata
    42241 aagcaaaata gattggtcct gcaaaccaga atgcgacaag aaggatcaac gtgcctgcca
    42301 aatagaaaag cgcgcttttg aaatcattaa aaaacaagaa aaatgcagta atccaagaag
    42361 cttctttttg ttccagttga agcaagattt tgtaactaaa gagaagcgcg cttaatagaa
    42421 gcaaaaacaa cgtagtatac atcaatgtat agccaattcc cccaccccaa tagcggaaaa
    42481 tctgataatc gatcaataga agaagaaaat aaacacttgc taaactatct tgctttccat
    42541 aaagagagaa gttctcacga aactttttcc agaatagtga accgagcttt ttctcttcat
    42601 ttttttgtaa tgataaatca tatacagaac tgttcgactt gcagttccta atgtgaaaac
    42661 aggcaagacg cacaggaacc atagtagctg taaatggata agacgtggaa tccattcaat
    42721 gatttctaag aaataatcat tggctttttt accaatcgat cgattcatca tccttttgaa
    42781 cctcctgtca aatccatccc ttcaatgaaa taacgttgtg caaaaaagaa cagcaaaatc
    42841 gtcgggatca agacaagtgt tgctcctgcc atcagataat tccattgtgt cgttgcttgg
    42901 ttctgaaaaa cttgcaagcc aatctgtaac gtgtattttt cttgatcttg gatatataac
    42961 agaggaccta agaaatcatt ccaagctgcg ttgaaggaat tgatcgcaat ggtaatcaag
    43021 gcaggtttcg tcaatggaag catcaaatga ctccaaatat acaaatgatt cgctccgtcg
    43081 atttcagcag cttcgatcaa ttcattattg atcgataagt aaaattgacg catcagaaat
    43141 atattgaacg cattgccgaa gaacgatgga acgatcaggg gcaaataagt acctacccag
    43201 ccgatcttgg agaataatac atattgaggg atcatcgtta caaaccccgg gatcatcatc
    43261 gtagaaagaa ccaaagcaaa catcagcttt ttcccaggaa aatcaagctt cgcaaatcca
    43321 taagcaataa aagaatttga aaggacatta ccgatcacta ctagcacagt gatgaataat
    43381 gtatttcttg catagcgcca aaaaggaaag gcggcaatcg tatccagata gttttcccat
    43441 acgatttttt ctgggaaaaa ggtcggagga taacgaacga tttcttccat tggtttcaat
    43501 gaagtaaaca ccatccaaag caatggaatg atcaaaatga ttcctattac tgtcatgagg
    43561 acataactta gtattttttt gtttgccgat tcacactggt ctttttgaaa taatccatca
    43621 tttgccgtca cctccagaat aatagaccca cttaggtgca agcttcaaat tgacaaacgt
    43681 cagaaccaac acgatcagaa acaggatcat tgacatagcc atcgcataac ccatatcaaa
    43741 agctacgaac gccttgttcc acatatgcag attataaaaa agcaaagaat ttgcaggtcc
    43801 gcctgttcca tttttcgtca tgacataagc ttcttgaaaa atttggaaag aaccgatcgt
    43861 agaggtgatc acatcgtaaa aaataatagg agtgattaat ggcaaagtaa tacttttgaa
    43921 ctttccccaa acgcctgctc catcgatttc tgctgattca tataaagatc taggaacatt
    43981 ttgtaatgta gctaagtaaa gtagcattgc tcctccagaa ctccatattt tcatcaaaat
    44041 caacgcaggt ttcgtccatt gtggatcaaa cagccaagct ggtccaggga tatggaacca
    44101 gcccagaaat gtgttgatca atcctgcaga tggagaaagc agctgcatcc ataagatgta
    44161 gactgctact cctgataaga ctgccggtaa atagaaagct gtacggaata cactgattcc
    44221 tttgattttt tgattgagta ctgtggctaa aaacacactg aaaatcgtcg tcagcggtac
    44281 attgaagatg acgaaataaa cggtgttgta taacgatttc caaaataaat catcgtgaac
    44341 gaacattctt ttgaaatttg ctagaccaat gaaattcatc ttggatgtca aattataatc
    44401 ggtgaaacta ccaataactg aaaaaagcat aggccctagc ataaatacca agaacccgat
    44461 aataaaaggc gagataaata aataggccca tcttgcttct tttttctttc ggatagataa
    44521 acgcttcaaa ttttcttgcc tcctctgtac ctagacagtc aaaaatggat tattgatttt
    44581 gcttgactaa gttttctact gctttttgtg catctgccaa tccttctttt ggtgattttg
    44641 ttcctaaaag aatctggtca atctgttcat tcactaatgt cgtgtaatcc ggagcatcta
    44701 aaggaactgg tgtgatcacc gtatttttaa agttttcgtc cgccatttga tagatcattt
    44761 ttcctttatc cgttaggttg tcattattca ctaaattctc attggctgtc ttgctcgcca
    44821 tgatatcaaa acttttttcg ccgaattttt cttgtacttc tggagaagaa agatatttga
    44881 tgaattcata agaggcctca ggatcttttg ctccgtatgg tacttccaag acgaatccgc
    44941 caccccacga ccaatggcct gaaccttctt ctttttctgg gagctgcatc acgccaaaat
    45001 caaaatcatc cggtgcattt tccatcaaac tagagtaata attgatattt tgggcacgca
    45061 tggctactaa tccggaaata aatggatcag atacaccaga cccaaattcg gcttctaatt
    45121 tattgatcgt atttttccca taataatctt gccagtcttg gatccactcc aaggcttcca
    45181 ctttattttt agtatcaatc ttgacttttt catctttgtc aaaccaacta gtcccgttat
    45241 ctgcgtttag cgcccataca tcagccccta aattccataa tggataaaaa ccgatgcgtg
    45301 taaattcttt tccttctttt ttatctagtt tacgtgctgt ttcttctaat tcatcccaag
    45361 ttgtcggtag atcttgttca ctgattccag cttctttaaa tatcttttta ttataaaaaa
    45421 tgacttgtgt atctgtattg aatgggatcg cataaggatc accttcatat tctactgtat
    45481 cccaaagctg cggataaaaa tccttagaag tgtctttttc tacatatttg gagagattag
    45541 ttgcttgctg tgcttctgct ctttgggcaa cggaatttat gtcctgtaca ataacatcgg
    45601 gtgcatttcc agctgttatt gcagataaag atttagtcca gatgtcaccc catggctgat
    45661 acttataatt tacatggatc tcgttttgtg attgattgaa atcctcaatg atttcttcga
    45721 tagcttcttt tcgtgcaccg gatccccaaa aggaccagaa atcaatattt tttcttccat
    45781 cacttgtttt ttcagaagaa tttgctgcac ttgaactggc atcgcttgca ttacttgatc
    45841 cgcatcctcc taataaaaac aatgctgaac ttgccagcaa ccctgtaaac aataattttt
    45901 tcatatttta cctccaaatt ttaatgtaac cgatgccggt tttaatataa cgatatcatt
    45961 ttgttctgaa aataacaatt tataaggtat gattctaaaa aaattattaa tgataccaat
    46021 actttatata attcgcgagc gctttctttg aattttttaa tctttcgtag cagaatgaga
    46081 atgtattaaa aatagattag gaggaatttt gatgtttaga caccagaaag aattgcagtt
    46141 tgaagcaaaa ccagatcgtc cgaatccatt aatcgcgaaa tatctgcagg agctgatcgg
    46201 cggccaatat ggcgagatga gtgtagctat gcagtacctg ttccaaggct ggagctgccg
    46261 aggagaagaa aaatataaag atatgctgat ggacattgca acagaagaaa tcggccacgt
    46321 ggaaatgttg gcgacaatgg ttgctcgttt attagagggt gcgcctgttg aagatcaaga
    46381 agcagcgatg caaaaagatc caacaatcgg tgccattatc tctggaatga atccacagca
    46441 cgcgatcgta gctggcttag gacctcgtcc tgctgacagc gtgggcaatc catggagcgg
    46501 tgcctatatc attgcgagtg gcaacttgtt agcagacttt agagctaatt taaatgccga
    46561 atcacaagga agacttcaag tagcacgtat ttacgaaatg atcgatgatc gtggcgtaaa
    46621 agatatgctg tctgttctcc ttgcaagaga tagctatcat caaaatctat gggaatgtgc
    46681 agtgaaagaa ttagaagaaa aagaaggttc aatcttagtc ccaagtactt tcccgcgtga
    46741 caaagaacga aaagacattg cttatgactt ctataacttc tcagagggag accaaagtag
    46801 tgaaggttct tgggctagtg gcaaagcact ggatggcgaa ggcgaatatc aatggttgaa
    46861 agaacctaag atcgaaggcg ctgcaccaaa attagaacca gtaacaccaa aaatgtatgg
    46921 gacacctcca ttcaagaaat aaatatctac ccgtagaaac acccgttttt tgttccacac
    46981 gctttgtgag caaaactgac taaagtcatt aatcataacc acccttcaaa agggtggttt
    47041 tctctagagc tataagctca aatcaccggc cagcgcctaa agacgctggc tttcatattt
    47101 tatgttcaag ccatattgcc tttgccagtt ttgcccacct cttaaaaggt ttatgtacta
    47161 ctccttagcc cttaaaagga tcgtcttact ctcgtacact cagcttatct aacgcactat
    47221 catgtttttc ttgttcttga atgtactttt tgatggtcgc ttcattttgt cctacttttg
    47281 tcacatagta tccttccacc caaaagtgtc gatacccaaa tttatatttt agatttgcac
    47341 aatctcttga tgatctcctg aatattggct cgatattgat tataaattat ttttcttcta
    47401 tactttggtg tgaatacaat gtggtattta cacatctact ttgtacgggc taaactattt
    47461 ccctttattg ctccacccgc atagcaagtg gttttgtatt tcaatcgctc ggcgcgctca
    47521 attaggtcta aagacaataa atctaaaaac ccgctgcttc actgacagaa acaacgggtt
    47581 ttcagaaaaa aatgaaatga aaaagatctc ttacggcaat ctattttatt tttttgattt
    47641 tttataaatg gaaaatgctt caagaagtcc aagaaataaa gccgtataaa aacaagaacc
    47701 tatgaaatct ttatttatta gatattcaac agaaatcccg ataacactag ccaacaatat
    47761 atttatcaga agtgtaaaat aaggatgctt tttatagaat agaactagtg ttgttttcat
    47821 agactctcct ttcttcatat ttccaattaa tcacaaattc acggcattac tagaaaaatt
    47881 aaaggggcgc agaagtggaa aaatactctt cgactttccc tacaaaccag gccatcttgt
    47941 gtttaataac tataccaaat ctaaggtacc tctaaatcta aattccattt gtggcggtga
    48001 cctccaattt ttaactcttc tatctcccat ccagtataca taaccttgat acttcgacca
    48061 cttatatatc gaacacacaa atacctatcc attgcaggag tactacctaa cttagttgct
    48121 acttgcatct aaataacagc tgaaaagata ggacttactc ttagtaaagt atctgaacta
    48181 ttaattttta aactatcatt tttatcctca actacatgca catctgttgc aacttcactt
    48241 tctgtctcat ccagataaat gattaaggaa tcgggaattg caatatcttc agctgacgct
    48301 ggaatagttg agctaaatta gtcatcatat ctttattata aaataaccaa cagcaaaaaa
    48361 tacaatgaaa aacaaacttg gaactaatgt atcattaata aatgttgaaa aattcagcaa
    48421 ctcattactg tatgatttta gcagcccaac caacatatac cctataaaag ctaataagat
    48481 ggttaggaat cctttagaat ttttactcat tcatagacac ttccttaaat aacttttatt
    48541 atagaaggta ttgtaaataa taatattgac aaaaagtgac tcaaaataaa aaaaacctta
    48601 cattatactg gaatgaactg tattgatagt gtacctaaaa gctctactga cataagatcg
    48661 tgtaatcggt aaagtaattt tattaattat acgggatgta atcaattaga gaataaacta
    48721 atcataaaag gtacttttac attcataatt gtcgctttga gattctactt tggttcacta
    48781 tctgacccaa ttgcacattt tcgatcatta caagtattgg tgtcgttaga acaactaaat
    48841 aaaaactagc ggtagatttt tcagaatcta tgctaatttc tgtatggatg ttccagtgat
    48901 ggcaaatttc tcttttcatt gtttttcttg tcgcatgata tgcctttttg tgttattcag
    48961 ttaaactata gaaattcttt cctagacaga tcttgatccc aaattttacg tttttgagca
    49021 tcgatatagt ttaaaatgac attactcata tctaaagagt ttagattttt taggactaaa
    49081 actgtcagtt gttctttttc ttctttctgt taaagtattg tcgcgacttt tcgtatacgt
    49141 taagatatgt cgtgaaaaaa caagttttgt gacacaaaaa aacgaatgac ttgaggaaat
    49201 cacctcaatc attcgtttaa aatgctatat attctttagt ttaagatacg gaaattaatg
    49261 ccatcgacca cactagtaga atgaacgaca tttacttggc ctttttttaa tttcgttatg
    49321 tttagcatat aaaaatatta tagagtttac ttacaatgct taaaacatat actgtataat
    49381 ctgatcaatt ttagccatgt cttgcaatgg taagttttct atttttttga gttttcgttc
    49441 cttaaaatca agagatttta attgtgtaat aattacttgt ccttttatat ctagctcttc
    49501 aggtaatgag taacgtgtcg gtaaattctt tatagtggaa gtaattggac atatgaccga
    49561 aaacattgtt ttacggttaa attcataacg agagacgact agtcctggtc gtcttttttg
    49621 aatttctttt cctacggagg gatcaaaatc aatccataca atatcacctt ttttaggaat
    49681 ataaattctt tcttctgaca ctataaaatt tctctccctt caggagttaa atcttcccat
    49741 tcgtctttct cataatactc ggcctcttcc ccaccactaa atggatcttc aatttttgga
    49801 actaacgtaa ttgttccatc atcagaatac acaacgatat attcttggtt ttctgaaggt
    49861 ttctttccgt tatcagaagg taaagttacc actacagaac ttccttgtaa tctagatttt
    49921 gtaacaagca ttatcatcac tcccttaata aaagtatact atataacact aagtaacgca
    49981 aaattcccct ttgtaaacta tctagaaaat tgttttgttt aaagtatatc ttattggata
    50041 taaatagaaa taaattgtag ccagttcatt ttttctttaa ctaaaaaaat aatccaagaa
    50101 acattgaacc tatggatcca aaagctaccc aaatactata gctaaccccc cgctaccttc
    50161 aattttgcag ataaaacgct ttgggagaaa atttcaaaga caacaggcca tcctatcatg
    50221 cccgattata aacaaaaagc tggctattcc ttttgctctg acaaatttca attgggaaag
    50281 ttcacgaaac tagcaggtga agaagtttca actgttcgga tcaaagaatg cccgcttcaa
    50341 atagaaacat tggttcaacg aatttcaact agacaagact ttgctattgt agaacgtgag
    50401 atcgtagcta tttttgtaga agaagggatt ttacatgatc caactcatat caatgtggat
    50461 aaatggcaac ctcttatcta taaattcaga gaatatacaa ctgccaacca gtcgttaact
    50521 ttgaatttta gattccaaga attcaaagag tcataatgat aaacatcgtt aggtataaat
    50581 aaaaaagact cgcagcacga gtaaaaaaca aatagaagct atacattaga aaggtcgact
    50641 gtgaccctat agatgcagta tatgcagctt atgagcattt cttctgttct ctttgttttt
    50701 gggatctgtg ctgaagtctt tttcgttttt tgccgctctt tctttgaaaa atcgattatg
    50761 ttataccttc tccattacta attcaggcat ctgctgagta atgatttttc gcgcaaaaga
    50821 aatatctgtt acccaaggtt cgatttgttc ttcagtcaag acaagcggca ttcggtcatg
    50881 gattggtgcg actgtgcggt taggttcagt agtcattatg attgattctg ccattttttc
    50941 atcctgatgg ctacgataaa aaccgccaat atacactatt ttttccttat ttgaaaacat
    51001 aaatttgtct ttttcttcat tccactcatt gggaaaacac aacgattttg caaaaatggt
    51061 tgatgaaagg tctttttttc ttctactgtc tctgcacggg cattaatcat caattgtcct
    51121 tttttaaatc cggtaaatcc ccacttcatg atttccggag tgaggatgtt ttcttcctct
    51181 tttcttaacg tcacaacaag atttgacgga aaaacttctc cagctgctaa ttctgctgcc
    51241 tgcttcggtt gtttcgtctg ggcttctcga taataattct gaaggagctc tgactctaga
    51301 tcaaaaaaat aacgaccaca catcctaatc cctcccaatc tttttttcta tcatacactg
    51361 caacaagaag ttcgcaccaa caaaacgctt tcaatttttg tagaactaaa aaagttgtga
    51421 caagtgacaa actctccagt gaatggtatt ctcctgccaa ctcctcggtc acaagtcaca
    51481 atattcaaca aacatgagaa gctgcttttt gaaattgttc cttgtgactc ggagtgaaac
    51541 ggcaggctta cgacctctgg gtaaacggtg ttcaaaagcc agtttctcgg tattaagcca
    51601 aatttatgca aaaatgtaga aagctatttt cacaaaattt ttcttaatac tcgaaactaa
    51661 gcgacttttt cacaacctct tccttaaacg gtgttcaaaa gcttgcatct gcggtaataa
    51721 gcccaaccaa acgaaaaata tgagcagcta tttttatttg gctgttctta ttacttgatg
    51781 cagggcagct ttttcacaac ctctccacta aacggtgttc aatcagctaa ccttcggtat
    51841 tagctcaaaa aacggcaaaa tatgaggaac tattttgccg tttgtttctc taatactcag
    51901 gtcaaagcgc tgatttcaca acctctaata cacggtgttc cagaagtagc ttcttcgaaa
    51961 aataagccga aatttcacaa aaatttgaga agcaattttc gtaaattcct tcttatttct
    52021 tgaagctgac cacttctgtc acaacctcta attattaaag aaccttttgc gaagttaaca
    52081 atctttcttt gatcaattga aaattctgcc taagtagtga tagatcctgt gtgactttca
    52141 acaataagat acttccctgg atttcagcaa tcaacgcttt ggcttgacgg tctgcttctt
    52201 catcggacag tttttcttca gaaagtgcca ggatattttg tttcgtatac ttgacccatt
    52261 gattgactaa ttctagtagc aacagacggt attcttcatc cactgtactc aactcaataa
    52321 tcaaattacc tacaggacaa ccatgataag tgatctgtgt ctcatgatca gcgaaaatcc
    52381 agtccaacat ttcttctaat gcttcttctg gctgttttcc agcatttaag atgtcttcga
    52441 acaattctgt ctgccatacg tccatatgcg catggatcac cgctagacaa acttcttttt
    52501 ttgaagaaaa gtaataataa aattgacctt ttcctgtatc agaagctgct agaatatctc
    52561 ggattgacgt ttcatgatag ccttttttat aaataagatc tttggtcgct tccaagatct
    52621 tttcctttgt tttcaatgat attctccttt ttcatttctc atagtcctat attatacagt
    52681 aaattcatca ttttttcttc ttaatcgttt aaaaaagact gtgccaaatt atctgacaca
    52741 gccctcacta taaaactgtt ctcatatagc tagatgttca ttgattcaag aactgcgagg
    52801 acaaaagcaa ttcctatctt atgatagttg ctctaatact tcctctgttg tcatcacttg
    52861 atctgcaata aagccaaagt tcgtcaacgc tgcatccatt gcttcttggc caggagcacc
    52921 aattgcatct gtcgctacca caacattgaa tccactctct accaattcac gcatatggga
    52981 atcgctacac aagtttccgt tcattccacc aagaattact gtgtcgattc cattttttct
    53041 caattggagc gccaaatcat tgctttctgg tccaaagatt ttatgaggag agctgatgat
    53101 cgtattttca tccaaataag gtttcaattc ttcgataaaa tcggctcctg aaccttcttc
    53161 cactgattca tattgacttt ttctagcaaa catctgctgc tcaagcatca tatgttctcc
    53221 tgcaccgcca aattgccatt tatggtcatg tgggtaaaaa taatgaggag aaataaagag
    53281 tttgtatcct ttttcttttg cttgttttac catttcaatc atattttcga tcgtattgta
    53341 tttttctaag atatcttttg tcaaaccaaa gccaccgcct gctggtttca agaactcgac
    53401 ttgcgggtca gtgagaacta ctgctgtatt tttattattg aacatggtgg attctccatt
    53461 cgttatttat tttaatacat catttagagc ttcactcatt gtcggatgag aatagatttg
    53521 atctctcaat aacgtataag gaagttttcc attcatagct agcgaaatca agttgatgac
    53581 ttcatgagaa tcttccgcat agatacttgc ccctagaatc aagtcagttt cagggtcgac
    53641 taaaactttg aatacacctt taggatcttc taatacttgt gctttaggga caccgcttgt
    53701 catatacttg aataatttgt aattgacgcc ttgtgctttg gcttgttttt ctgttaaacc
    53761 tacattggat aaagtcggag tgataaatac actgtaaggc acagctttcc ggttattcgt
    53821 tgttcgttta ttctcgccct tcaactgatc cataatgatt cgataatcat ctagagagat
    53881 ataagtgaac tgcaatccgc ctttgacgtc tccaatcgcc caaatgttgt ctgcatctgt
    53941 acgaaggtat tcatccacag cgattgctcc gcgatctgtt agtttaacat ctgtattttc
    54001 taatccaagt gatgctgtac ttggttttct tccagttgca gccaaaactt ttgacgcttg
    54061 gattgttact tcttggccat cttctgtaaa ggtgacggca gctgttgatt cttggtctgc
    54121 tacttgatct acagatacac ctagatggaa ttcgattccc gcatttgtca tgtcttctaa
    54181 aatcatttgc gcgatatctt catcttcacg tggaagaaat tcagaatggg catcaagaac
    54241 gacaacttta gatccgtatt cattgaacat tgatgcaaat tccaagccaa tatatccagc
    54301 cccgatgatc actaattttt ccggtaattg ttcctgatcc atcgcttgcg tagaatcaat
    54361 caagtagcga cttgtattca atcctttgat tggtaaaatg attggttcag aaccagtatt
    54421 gatgaaaatc cgttcgcctt caacaatcac tttttcacca ttattcgtca cttcgatttg
    54481 atggttagaa agaaaacgtg ctgtaccgtc catcactgtc ccagttgcct catcgctgat
    54541 catatgataa tttttggcgc gaagcatgcc cgtcaatttt tctttccgag caacagcctc
    54601 tgtaaagtcg attcctcttt ctccattgaa aatcaatgat ttagaaggaa tacagccgat
    54661 gttgatacat gttccgccat acatacgtgt tgacttttca acgactaaaa ccgattcacc
    54721 ttttgaagct aacgccttcg ctaaagtctt accgcccttt ccaaaaccga tcacaatatt
    54781 ttgatatttt tccatcattt ttccctcgct tcttttttac ctaccgattg gtacaaaaat
    54841 atgataaccg ataattgtct attctccaaa tcatctgctt tatttgtcaa aaaaaaccag
    54901 acaaaaagcg gtcctttcac gtttttagtc tggttcgatt tcctttattc ttctaaacaa
    54961 tcgttacttc tacatcgata tttcctctag ttgctttgga gtaagggcag aattcatgcg
    55021 catcttctgc aattttttgg gcttcttctt cgctgatgcc atcgatatgc acttctaata
    55081 ctacaccgat ctgatagccg ccatcatcta aattataaag agagacacgt gcttttactg
    55141 tggactctgc tgtcattcct gcttctttga tcatatgttg taccgcccca ttgaaacaag
    55201 aagcataacc tgctgcaaat aattgttctg gatttgttcc ttctgcatgg attcctggag
    55261 gagtgatttt catatgcatc gagccatttg gtgcctcgac ttctccattg cgcccgccat
    55321 ggttgatcat tgctgtttcg tatgcttttt tcattgtact gctcctttcg attgaccatt
    55381 tgctacttgg ctataattat agtgtatgac aagtaaggcg ctttctacaa aaattctgct
    55441 tattcgaata ccagaatgcc gtcttctact atttttccaa aaaacaaaaa aatactactc
    55501 gtgaacaaca gcgtcatatt tgttccaaaa taaatagcaa tcttttctac ataatctttt
    55561 atatgattga ttttaagata catatatacc agaaagttga ccccataaac caatactgtt
    55621 aaaaaaataa ccatattcgt taccattttt tcctcctttt gctggtctcc ctaccagcac
    55681 tcgatttaac cataccactt tttttgccgt ccaagcaact agcctttcaa aaagactggt
    55741 ttattctgct gttaatgatt caagatcaga aaaatgtccg aataattttg ctaattttac
    55801 taacgccaac ttgttctttc cgaattcatc attttctatc tgtaatacta gtaacggctc
    55861 atgtaagctt aaacggatca aaaaccagcc gtttccgtat ggctcttcta gatcatatcg
    55921 aataccttct tcattttccg ggtcgaagtt catccctttt tcttcttcca acagtcgctt
    55981 catttcttct aatatcttgt ttccttgttc gcgtggttca tcgctgaaca attttaatcg
    56041 gatttcttgt acttctacgg gctgtttcaa ctctttgatt tgttcatcta atgtgatacc
    56101 ttttcttttt aattctggca aaagcatcag gatctttgcg atgacatatg caccatcatc
    56161 cagaaaatag ttttccttga atgcagcgtg tccgcttgtt tcgatggcta gctgtgtatc
    56221 tttcccaaga cggttaagtt ctaatgcttt attgattaca tttcgatagc cggaaatata
    56281 acgaacttgg atgcctcctt tttcttcaat gaatctttgt agatgagaag aagtagggga
    56341 attcgtcacg attcttgttc ctggatgctc ttttaatacg attgtactta atactgcgat
    56401 caaattattt cgattgatca ctgttccaga agcactgaca actgcagaac gatccacatc
    56461 tgtatcgaaa atgatcccaa gatctgcttc atttgctaaa acagcctgct tgatactttc
    56521 catcgcttct ttattatcag gatttgggat atgattagga aatcggccat ctggttccaa
    56581 aaattgggaa cctgttgaat ccgcacctaa gctattcaat actttttcag caaagaatcc
    56641 accagcacca tttccggcat caacaatgat tttccaacca tttagtggtt tgctttctag
    56701 tgttccaatc ccctttttaa tttttgtgac taaatcttgc gcataaggtg tcaaaaggtc
    56761 tgctttttct acgcttccag tttgttcgct ttttattttt tgctgctgtg ataggataaa
    56821 agcaatatct tctttttctg ctcctccttc tgaggtaaag aattttattc cattataata
    56881 atagggaaga tggctagcag tcagcataac cgcagcatcg cacgagaact gttcaaattg
    56941 agtggacata aacatagcag gcgtagtagc taattcgaaa tcgatgacat gtatcccttg
    57001 ttctttcaga ctttggatca acgcctcttt cagtgctggt ccgcttatcc tactgtcatg
    57061 accaatccca atcgtccatt ttttatttgg atcggttgat ttcttctttt tctttatcca
    57121 gtttgctagt ccccagccga tcttttttac catgtctgtc gtcaagttta cttcatatcc
    57181 ttcaactggt aatgcgattc ctcgaatatc cgatccattt tgcagcgctt tcatatcttt
    57241 catataaaag tcctcctcat ttattccctc attttttcca gcttttctgc aaatcgctgt
    57301 gcttcttctt ctgagcggca aataataatg aatgtatcta caccggccat cgttccgaca
    57361 acttcagggt aagccacttc atctagccaa ttcgttacca catcggcacc atttcgttca
    57421 gtcaatacga taaccatgaa ctgaacagac tggatacgca aaacctcgcg tctaattgct
    57481 gtacgcaaac gttcttcatt taaagaaaca gatggctggt taaataatgt atagcgtact
    57541 attttgtttt cattttgact ttttactaac ttcatttctc gaatgtctcg agaaatcgtt
    57601 gcttgagtca catcggcgcc tgcttcatgc agccgcgcaa gcagctcttc ctgtgtccca
    57661 ataggttgtt ctgtaatgat ctggcggatc agtgcttgtc gctgtttctt tttcatatta
    57721 gacacctctc aatgttgatt atagcaaaag ataagtaata tttcttcata ttttggtatt
    57781 ttttactttt attttttgtt ttcattcagg ttgctaacct ttttctattt taacacgcaa
    57841 aatcgtcttc attttttcag gtgctgattt tcttggatcg ctgatgtaaa tctctttgtg
    57901 ttctttagaa gctctttcat agccttcttt tgcgatgaat gcttctaatt tctcaaacgt
    57961 tgctggttct tcggcatagg gcccgacgtg taagatttgg gcacaaagac cttcttccat
    58021 ctttttgaat actacttgtt ctttcaagtc ttccggaagt ttgctagaac gctgaatggc
    58081 ttcttgtgct atcgcttctg taacaaagtc aggctgtcgg atcatcaatt gataagaaaa
    58141 atgttctttt ttcatcactg gttcatgcaa atacttttct tgcagtcccc attgtccttc
    58201 cagtggatag acagtataca tctgataatc aggaatcagc caattttttt taggcgacat
    58261 gcgtattgca tagctgactg catatagaca ggctactctt cgtttaaagt cttcctgatt
    58321 cgggtcgccg atccctctga tgctaaagaa tgatttttta ggaacctcta gtatttgcgg
    58381 gctttttttc atactatagc tcttgtcttt acgccattca attttttcca tttttcttcc
    58441 tccgcgaaat tccatttagt tatttattat catacctctt tttgagtgac ttggctaatc
    58501 gtgttgacac tatttttcag tttgtgctag aataagtgaa gtaaataaat cgtacagata
    58561 acacgtttcg gcgtgtcgag agagaggcgg tttctatttt tataatagaa atcactctct
    58621 ttttttacga aattttttag aggtgatgta aatgacaaaa caaaaacagc tgcttttagt
    58681 acctgcagta attgcaacag ggatgatgtc ttttgcgggc gtattgatcg agacggccat
    58741 gaatgtaact ttcccaactc ttatcagaca gtttgattta acgactgcac aagtccaatg
    58801 ggtaacaacg atttatcttt tgatgatttc gatcattgtt ccgctgtcta cttatttgaa
    58861 tcgcaatttt agtctcaaaa aactcttttt agcttcaaat ctgcttttct tggcaggtat
    58921 aatgatcgat ttcttctctc ctaccttcat ggtcctattg tttggtcgat tgctccaagg
    58981 tgcagcgaca ggtatcgctc ttccgttgat gttccatatt atcttgacat ttgcccccct
    59041 caatcgacga ggcgcgatga tgggtgtcgg tactttgaca acggccattg ctccagcaat
    59101 tggccccact tatggaggca ttatgacttc acattttaca tggaatcata tcttcctgtt
    59161 tcttgtgccc gttttgtttc tttctttgat tatcggctgg tttgctattc ccgagatggc
    59221 agtacaaaaa agtggttatt tggattggat aagcgtttta ggaatttgtc ttttgtttag
    59281 tggaagtcta acatttttga gtacgttggg aacagtttcc agctggattg ctttaatcat
    59341 cggcggtatt ggctggttcc ttttttacta tcgaagtaaa aaagtggagc atccactgat
    59401 ccgactgtct attctttcaa ataaaacatt ccgcttgttt ttgattggct tcttagttta
    59461 tcagttttta ttacttggtg tatcttttgt cttgccgaat ttccttcaga tcgttcaagg
    59521 aagtagtcct tttgtcgctg gattagcgat gcttcccggc gcagcggttg gtgctttgct
    59581 ttctcctttt tccgggaaaa tgctggatca atatggtccg aagaagccaa tttttgctgg
    59641 gctgattctt tctttgattg gttggctagc attattccta ctcataggac acgcttcagt
    59701 gggtgtattg attgcttgtc atgtgtttta tatgatcggt atcggattat cttacagcaa
    59761 tatgatgacc accggaatga atgcactgaa tgaagaacta caaggagacg ggaacgcaat
    59821 gttcaatacc ttgcagcagt tttctggcgc tgtggctact tcattagtag cggtcattat
    59881 caattacgtc cagcatcata cttcccataa ctatgaagtg tctactacat taggatcaaa
    59941 agcagcatta ggcgtcttgt tgctgttgct tctcgtaagc tttgctcgat tcgcctatta
    60001 tctgttcttt gctaaaaaag cgtagattcc atatacggca ggtgttgcat ctgccgtttt
    60061 tttgtgtgaa aatggttgtt tgtaaaagga ggctttttta tggaaaaaat tgccattatc
    60121 ggtggcggga tcattggtat gaccctagcc agttacttag atacatcaaa attcaatgtt
    60181 gctttatttg atgaagggac aggacaggca actaaagcta gcgctgggat tatctcccct
    60241 tggttgtcga aacgcagaaa caaacaatgg tatcgtctgg ctaaagacgg cgctgctttt
    60301 ttccctaaac ttataaaaga tttccaactt gatcaaacga tttacgcaca atcagggaca
    60361 cttttgcttc gacctgaaaa agatttagct gaattggctg ttcttgccga gaaacgaaaa
    60421 gaagaagcgc cagaaattgg aaacatcgaa tggctttcac ctgaacagac atctcaagca
    60481 cttccgttat tgaaaccagc agtttcactg cgtatcagtg gtggtggtcg tctggatgga
    60541 aaagcatatt tagaacatct tggtcagcgt ttagcacaaa aacaaatgga gcagatccag
    60601 gcaaaagtca ctttgcataa gaagagcgat tcttggctca tcaagggacc gtttggagaa
    60661 tacacagctg atcgtgtaat tttgacacct ggcccggcac ttaagccttt attacaagaa
    60721 ttaggctatg ctgcagatat acgtccgcaa aaagggcagc tcttagcatt tcagacatct
    60781 tataagatga gtcaagactg gcctgttgct atgcttgacg gagaagctga tttcattcct
    60841 ttcatggatg gaaagatcct tttaggtgct acccatgaaa acgatcaagg ctgggatttg
    60901 gctcctacta gcgaagctta taagggattg actaagagta cagaacagtt cttgactgat
    60961 ccagatcaga taaaaaactg gccatacgag ttccgtgtag gtacccgtgc ttatacgtca
    61021 gatttttccc catttttcgg cgtactgcca gatgatccaa gcttactggc tgctagcggt
    61081 ctaggctctt ctggcttgac cacaggtcct tatatcggct atctattagc caacttctta
    61141 aatactggtc attggcctac ggaagattat caaaaggaca tctccaccta tattacgaaa
    61201 aatccatcat agaaaaacag ctttttcaag taaggatccc gagcgatatt gcgcatggat
    61261 tacttcttga aaaagctgtt attttagttc aatttctgaa tcaaattctc caaactttct
    61321 tttgcttcat ctggcaagag atcttttcct atctgagctt caatgaatcg taaacgaata
    61381 tcaagtcgtt gtttcaccag atttttatag gacgtatcct caaaagaaac aggaaaatct
    61441 ggtataggta aatagtggat gtcttcaaat ggaccaaacg acttgaattc tgccgtttgt
    61501 tgcacgattc tttcaacgat tgacaatgtc gtttcaggtt tgattttttt atcatcgaaa
    61561 tatccagtat tcaggacata gcaggctgtt tgctgtttca aaaacaactc tcgaaaagct
    61621 tgatagtctt ccctaagagg atagacacgg aaaggattag caaatggttc aatgactagc
    61681 tcatctagct gtctttttgt agtgatattt tccgcgtctg atcgttttgt tgctaatgtt
    61741 gcaccaaaag acgctgctaa aactgggtca ttgatcttga taattggcgg aagcgaatca
    61801 tctttcatga tccaaaaaac agcatcgatc ttttcgctaa gatgatcgac tcggtcgggt
    61861 gtcgcataac gtgatttgac tgtccgccca tttccgtttc gtatatctcc tgttactagg
    61921 actttttctc ctttacttgt acatgtcacg cccacattct gacaagtaag gaaagaagaa
    61981 atggccggat catcagacgg atagtcttgt gttttatcaa agtaagaagg ttccaaggca
    62041 gtagcaaaac cattttttcg agaaataacg aaagcatcgt catgcaagat cgaaacagag
    62101 tgaccttccg tatgttttgc taaggtaatc gttgattttc cagaaccgga caacccaaat
    62161 acagccatcg tataggtctg gtcattacta gcatattgtt tcatcccacc gtggcaggca
    62221 ataaagccat tgcgatttcc caatgcccaa gcaagcgtca aagtcgcttt ttttaattct
    62281 ccaaagtaac gtaatcctag cacagccgct gtattatgga gagcatcaaa caaaatgagt
    62341 ccatttggaa atgtttcatg tgtccattcg ggatcacaaa agatataaag atctccctca
    62401 tcaaaggaaa cagacttttg ataagtctct aagatcttcg aattcgctgg ctgaaaattc
    62461 agcaaataag aatacaaatt gttctcaaat ccttctggaa tcagcaaatg actttgcaca
    62521 gaaaattctt cagataggcc aacgattact tttgtatggt aaaactggcg cttgcgactt
    62581 tgatacacag cttctcttaa aattttctcg tatttgcttt gttccttgtc taagtcctca
    62641 aagatccgcc gagcacttgc tgttcttccc acaatgcttc catcattgaa tactagtgtc
    62701 ctaacatcag ctggtaaatc tagttcttca gcatgtgaga ttgttaaatc tgtgatgatc
    62761 gttcctggac tcccttttgc tagttgataa gctgtcttcc tatcaaaaac ttcatgaaca
    62821 ttattaccgt aaaatgtcgt ttctacaatc gatcgaatac tggataacag tggatttcca
    62881 cttgtgattt cgtttaattc gagactctct tttgtactca tggctcctcc tcattcccta
    62941 aacaaaaaaa cgttttcttt attatacatt attcgagttt ttatttgtac tgctgcgctg
    63001 tgggaagcaa acgagttatt tttcacacaa aaaaaccgag aacttgaata aacaagtttc
    63061 tcggtttcat cattttcctt ttatcggctt agtaccagcc gtttgctaac cagaatgttt
    63121 tagcagcatc ccatgaacca taacgagatg ttacatattg ttctgctaca cgttcttgat
    63181 tggcagctga atagtcgccg tttaagtatg aagcatctaa ttgataacgg ccgatgtaac
    63241 gtccgttagt agctgtgtat gaaccgcctg attctttttg tgcgatccat tcttttgcag
    63301 agcttgaagt tggcgctgtt gcagcagctg gggcagcagg agctacttca actgtttcaa
    63361 caggtgcaac gtatgtatgt tcttgcgttg ctgtttcagt tgtagatgct gtattttctg
    63421 ttgttttgtt ttctgttgtt gctgaagaat catttgaagt tgggattgtt aattgttcac
    63481 caacataaat gcggttgatg tttgcgatcg aatttttttc agcaattgca tcgatcattg
    63541 agttgtctcc tgcaaatttt tgtgagatct tagataatga atcacctgat tttactgtat
    63601 aaacttcatc agcgtgagca tttgtagttc ctacaaacat tgcagtagca ccagcagcaa
    63661 aagttgtacc taaaacaatt ttcttaaatg aattcatatt aaactccttt ttttctccgt
    63721 tttttattct ttcgacgcta ttaactttat catttagaaa tatttcatag gtaaaagaaa
    63781 catgacattt aatgacaaaa taacgaatta tttaatattt gtaacattta aacaaatatt
    63841 tttttgatac aaaaccataa aagccttgtt gtataagcaa agtaatcgtt tttctatgtt
    63901 tttttatttt tgaatgaaaa acgcagattc tgtaacattc actgcaataa tccataaaaa
    63961 aaagcaaaaa aatttttgat ttttatcaaa ttctcttaaa aaaatgtaaa aaatacaaaa
    64021 aaaccagtaa ttgttacaac aattactgga caaaaacttt gaataatgtt aactattttt
    64081 ttattttaac tttctccgca ataatttctg ggcatgttcc aattcgttta taacgacttc
    64141 ttctgtttct ttagctaata tttcatctaa tacatcaagc catttttccg gttcttttgt
    64201 tcctagacgt ccaatagccc aagctgctgt tcctctgatg acagggcgga catctgttaa
    64261 acattctgaa atctcaggca atgccgttcg atcacctaga ttagctaaag caatcaatgc
    64321 gtttctctgc aaaggtttct tcccacgcca tgaaccagct aaatgcccaa attgctgttt
    64381 gaagtcttta ttagacatcg aaagcattgg ctttaatttt ggatatattt cgtctacttt
    64441 tggttccatc tcttcatgaa aatgaaaatc ttttccttga ttgtaagggc agactaactg
    64501 gcagatatca catccataaa tgacatttcg cattttttta cgatattctt ccggcatcat
    64561 cccttttgtc tgagtttgat aagacaaaca tcgctgggca ttcattcttc cgtcaccaag
    64621 caatgctttt gtcggacaag cagtcacgca gcgcatacag tcaccgcaac caaattctcc
    64681 tggtttatca ggctcaaata caatattagt aacgatctca ccaagataga caaatgaacc
    64741 gaactcttca gtgatcaaca atccgtttcg tccaataaat cctaaaccag ctcgctgtgc
    64801 tacagcgaca tcgatcagtt ctccagtatc tacttgcgga gctagacgcc attcctcttc
    64861 tttttgccat ttttctgctc ttgtttggat gaattcgatc aatcggttca aacggtctct
    64921 gagtatatca tggtaatcga tcccccaaga agcacgagca aactgcccgc gtttttcatc
    64981 cctaggcact tcttcatgga tcctagtagg atacgcaagt gcaatggaaa tgatcgattt
    65041 cggctgatca aatgtcattt ctggataaag acgctcatcg atatttggat gttcaaagcc
    65101 agaagtatgg ccagctgctt tttgttcttc caacgattct tttaatgaat caaaaggttc
    65161 cgccgtggtg aacccgattt tgtcaattcc taatcgtttg ctttcttgta tgatttcttc
    65221 ttttaatgtc atggtcttcc tcgcttgctg ttaacggctg tataacccat aatatagttt
    65281 ttcttttttc agctggacaa actggatctg ctgatcggca atcttctttt cttccatcca
    65341 tttttttctt gcagcaaata cttcccaata atttgttgaa attaattttc ttttgttatc
    65401 taatgcatta aaaaaattca atgaaactgg ttttgtactt aacagttcat ggagccttac
    65461 ctcttcccat ggcgaaaact cagacagatc gcgggaatac aatacttctt catagagatt
    65521 tttttgctgt gtgtacgtga atgtttgcgg gattttccca ggcctagcaa tttctactag
    65581 acgattataa aacatattca ttaatttgct gttggcaata aattgacttt tataataggc
    65641 cgactggatc tttttgatta ctccttctgc tttgatgact gaaaataatg caggccatgc
    65701 tttgacggtt atttcgtcgt tttgtttaac taatacgcca ggtgtgaagc cgactggaga
    65761 aaggaacaca aaataaccga taccggtatt ttcatctaaa ggctgaaatt catcaaacaa
    65821 ccatttgcct atgtacagct cttcatctgg ttctgttgtc tcattttgat ttgctatgaa
    65881 taatttagct aattctgctt caagaaattg aaggtcttga tccttgtcgg tattttcctg
    65941 ctggctgatc aatcgaaaga cttcttcttt aatcgtatat ttatctttac gtgtaaaatt
    66001 catagccaca ccttccttcc ttactctaac tataacggaa tttcttcaaa aaaggtatct
    66061 gtacgacgaa aaacagcata attttttttc atatctctta taaaaaatgc aaggtctgct
    66121 cctcaagcta gaccttgcac ttttcagctt tcttttgttt gtgacaaacc ttcatggatc
    66181 gtttcaatat tccatttcat catctgatag taagaatctc cttgttctcc ttcttttgct
    66241 atggaatcag tgaacagttt atcatagatt ttcaaacccg tttcttttgc tacccgttcc
    66301 atgcttcttg agtctacact ggtttccacg aataaaaccg gtacttcttt tgctcttatc
    66361 tgatcaatga tcgctttcat ttgatcaggc gtaccttgac tttctgtatt gatctcccat
    66421 atataagctg ctggcaaatc atatgctcgt gaaaaatact tgaatgcccc ttcacttgtt
    66481 actaataatt ttttgttctc ttcgatagaa gcaaaacttt ccttcgcttg tgtatctaat
    66541 tcttttagtt tttccacata tgcttctgca ttttttttat agagtgtcgc attttctgca
    66601 tctttttcag agaatatacg tgcgatttcc tccacatatt ttattccgtt agataggtct
    66661 agccaagcat ggggatctgc ttttgtatgt tcttcaccgc tagttaaata aagaggttct
    66721 acatttttgc taactgcaaa ataatctttt ccttcttctt ttttagccgt ttccatcaag
    66781 ttatcgaacc agctgttacc tgtttcaaga ttcaaaccgt tgtataaaat aacatctgca
    66841 tcgcttgcct ttttgatgtc ttctggtagt acttcatatt catgcggatc tgttccgact
    66901 ggtacgatac tgtggatatc tatttgatct gttccgacct cttttgccat gtccgccaag
    66961 atcgaattgg tagccacgac tgacaacttt tctttacttc cttcatccgc ttggtcagaa
    67021 gcctgctttc cgcaaccggc taataccaag aaactaactg ccaagattaa aaagagtgat
    67081 ttttttgttt tcatctatct gcttcctttc tgaaataaaa ttccttttgt tggagaaaat
    67141 aaaaaagcaa ggataaaaaa tgcggtacat gctaacacga tcgtagctcc tgatggccaa
    67201 ttgtaactat aactgaaaaa cacaccgaca actgcactta gcataccgat tcctgcagct
    67261 gtaatgatca ttttcagtaa atggttcgtt agcaagtaag ccgtggcggc tggtgtgatc
    67321 aacatggcaa tcaccaagat tgttcctact gtctgtaaac tgactacagc cactaatgtc
    67381 aaaaagaaca tcaaaagata atggatcagc gatgtgttca gcccataagc ttttgccatt
    67441 gtcggatcga atgatgtgat cttcaattct ttataaaaga aaaagacaaa tatcaagacg
    67501 attccactaa cgagtgctgt cagcaacaaa tcgctttccc taacagctaa gacattccca
    67561 aataaaatat gatacaaatc tgtcgcactc tgggcatatg aaatcaagat aatccctaat
    67621 gcaaaaaagg agctaaagac aattccaatc gctgtatcat ttttcaatcg gctccgctga
    67681 gtcacgaaac caatcactgc tgctgttagc atcccaaaag cagtggctcc aaagatgtaa
    67741 ctaaaaccaa acatataaga aatggctaca cctggaagaa ctgcgtgaga gatagcgtct
    67801 cccatcaaag acatccctcg taaaataata aaagaaccga tgactccaga agcaagtcct
    67861 acaagcatgg aagtgaccaa agcgtattgc aggaattgat aattcattaa tccatcaata
    67921 aaggattgga tcattttttc tctcctcctt ttactaaatg tctgatgatc tcaccatagg
    67981 ccaattgaag gttcttcgat gtaaagactt cttgtactgg accggaagcg atcagctgtt
    68041 tatttaaaag aataacctca tcgaaatatt cttctacttt atgaagatca tgatggacga
    68101 tcaaaatcgt ttttcctgaa ttcttcaatt cctgcaagat gtcaaagatc tttcgttcac
    68161 ttaacgcatc aatccctacg aatggttcat ctaaaaagat ccattctgct ccttgggcta
    68221 gagctcttgc aataaaaact ctctgaagct gtccacccga tagttcgctg atctgtcttt
    68281 tggcatattc ttccatccct acttttttca aagcttgtct tgcacgttct ttttcttttt
    68341 tcccaggtct ttgtccaatt cgtaaagatg gatatgttcc taaaagtaca acgcctaata
    68401 catcaattgg aaaggaaaga tccaattcac ttcgctgttc cacgtaggct atttttttac
    68461 ggactgagtt taccgactgt ccagaaaagg tgactttacc agtagtagct ggtatcaact
    68521 ctagcaaaga tttcataaat gttgattttc ctgcaccgtt tggtccgata ataccggtaa
    68581 ttttttgtgg atttatcgtc aagttgatag ttttcaaaac agttttccct tgataagcgg
    68641 ctgaaaggtc ttgaattaca atggccgtac gttccaaatc ttacactcct ttttaggttt
    68701 acctaacttt ttatttaaat atagtttaac taaaatggaa agcattttca agtagaatga
    68761 tgaaaaagtt tttttcgaat tttcctcgca ttttatgaaa attttctgta gaatcacatc
    68821 aagagttcaa taaggctaac ctaataatga aaaacatgtg ttgaaacgtt tgattatttt
    68881 ttcttgttga ctcaacaacg aaaggagttt ttgtatggaa gaagaaaagt taactcgaag
    68941 tcttagtgcc cgtcatatcc aaatgatcgc actaggtgga acgatcggtg tcggtctgtt
    69001 tatgggtgcc tcctcaacca tacgttggac agggccctca gtgatgggag cctatgcgat
    69061 tgcaggattc tttttgtatt tgattatgcg tgctttaggc gaaatgcttt acgttgatcc
    69121 ttcgactggt tcttttgcaa attacgcgag cgagtacatc catcctgtgg ctggctactt
    69181 gaccgcttgg agtaatattt ttcaatatat tgtcgtagga ataagtgaag tgattgctgt
    69241 aggatcttat atgaattatt ggtggcctga tttgccggca attattcccg gaatcattgt
    69301 cgtcttgttt cttatgctgg caaatcttat ttctgtcaag gcgtttggcg aattagaatt
    69361 ttggttttcg atcatcaaag tcataacgat cattttgatg atcattgcag gtcttggggt
    69421 aatcttattt ggatttggta atcatggtca ggcagtaggg atttcaaatc tttggaaaaa
    69481 tggtggattc ttcactggag gcgtcaaagg atttttcttt gcattatcga tcgttgttgc
    69541 ttcctatcaa ggaatcgaac tgatcggaat gactgctggt gaagcagaga atcctaaaaa
    69601 gacgatcatt gaagctgtcc agtccactat cggtcgaatc ttgatttttt atattggtgc
    69661 tatttttatc attgtgagta tctatccgtg gaatcaattg agtgagattg gttcaccttt
    69721 tgtacaaact ttttctaaag tcggcattac atttgctgca ggactgatta attttgtcgt
    69781 gattacagcg gcattatcag gttgcaattc agggattttc agcgcaagtc gtatggtcta
    69841 tacacttgcc ataaatggaa agatgtctaa aaaatttctg aaactatctc gtcacggtgc
    69901 gcctttttat cctgtcgtag caatctcagg tggaatctta attggtctga tcttaaatta
    69961 tcttctacca atgttcatca accagtcaga aaatattttc gttttcgtat acagctcaag
    70021 tattttgcct ggtatggttc cttgggtagt gattttgatc agcgagattc gcttcaaaaa
    70081 gaagcacgca gataaaatgc atgatcatcc ttttaaaatg ccactatctc cttatacgaa
    70141 ttatgtgaca cttgcttttt tagctatcgt attgattttc atgtttatca atcctgaaac
    70201 gagaatctca ttgattattg gactcgtttt cttgctttac atgacgatcc attactttgt
    70261 acgcgaaaaa agaaccggaa aataaaaaaa gaacgaagct tcaccttagt ggaagcttcg
    70321 ttctttttta ttgcttttat caattcaatt ttagcgtctc accgggagtc aggaaataat
    70381 tctccatgct catcccattc agcgacaaga tcgtttctac tggtacgcca gttcgttcgg
    70441 ctatttgatt tggaccttct ccttccaaaa ctacggttgt cgcagcctgt gaagtcgcgc
    70501 tgttggtatt agtttcagag gaatctgttg tgtcttgtgt tgttcgagct tgcatttcag
    70561 aagcttctac cgactctgct gtctcagaat cagaagatgt tgtgtcttgt gtgcttgttg
    70621 actctgcttg aagagaggcg ctagtctgca aataaatatc ggaaatctta gcgacatgat
    70681 tcgtataatt agccgataat tgattgatca aagtatctaa gtctacaccg tctttatttt
    70741 ctgctgcctg atacgctgca cgtaattttc tgatcccttc gtcggagatt gcttgaagct
    70801 cacgtgcttt ttggttagca actgctgata aaccagctat tccctcttga tttccctgaa
    70861 tttctgtctg gtattcttca atcaatgcag gcgtcttttc ttcgatcttt ttcgaataat
    70921 catttacgat tgcttgaagt tgctctggca aaccatttgc tgttttttct tcagaagttt
    70981 gtgtctcttt tgttttagtt gatgactcac ttgtttgttt cgtctctgtt ttctttgtcg
    71041 ttgtttccgt tatggtcgta cttttcgctt ctgacgaatt ttttccatga aaatatagac
    71101 ccgcaactcc tcctgctatg atcaaaaaca cggcaactgc tgccccaatc atgatcatcc
    71161 gcttacgagc tgcctgtttt tgctgtcttc ttcgggtcat ccgaacattt tctccccact
    71221 cattttcatc atacattttt ttcaccacca atttttatgt ataatagcgt tatcaaacgc
    71281 ttcatattct tattgtagca aataattgtc gctgtgcaca tttttatctt tgttatttat
    71341 aagaaaattt caccagttga gatgattcca agattgtccg tcgatttctc cttgcagctg
    71401 cattgttcgt tcgtctatct cagccatcag tttctttatt tcatataaga gcgcacggtc
    71461 ttgatattct gatttttcgc ttaattcatc taattgttgg atcagccaat catttgtcat
    71521 aatgaagttc ctttcatttc ttgcagtgta aaggtcaagt cttcgatctg ctcttttgcc
    71581 tcagtcagtg cttctacgat atatgcttgt ttttcagatt cttcttcctg cattttctga
    71641 ttttcctgta ctctttgaat aaaccagtca atccgctgag tcagcgatgg tttgccttcc
    71701 aatgagagat actgctgata agcaattagc ttctcccaac gtttttcctg ggataaatac
    71761 ataaattgtg ctaaaacgaa tggcggaaga taggtcatat ggaatttatt tgcgattcgc
    71821 tgatacggcc tcaaaaattc ggaaatcgta tattcttctt ttcctccagc ttggtattct
    71881 ttttccgcca cacctgttgt caatacgatt cctagttctt tcccttttaa tacatgtgct
    71941 gctcgttcca agacattatc ttgccaaatt tttaaatgag caggagaact ataccagtaa
    72001 aacggaaact ggaaaatgat ccgatcatgc tgggccaaga gctgtagttc agtctctata
    72061 tctatttttc cgtctggata acttgattcc aaatgatgcc aagtagctgg taaaccagca
    72121 gaagcttctt tgaaaaattg ctgatttaaa gattcttcga tcgttggatg gctaatgatg
    72181 ataagtgtac gcatcccttt tcctcctttt tagtcttcgc tttacagtgt agcataaccg
    72241 ccacaagttt cttttgccga tgcttgtcat tttaaccaga ctaatcaggt tgtccaagaa
    72301 actgcggttt gtttttccaa ctgttttttc aaggtatcca aagcaatatt cttaaaattt
    72361 tcgtttttca tacgtttacg atagttcgta gccgtttctc cggtactctt tttgaacatt
    72421 cggctaaata cgactagact attgaaccct acttgatagg caatactttc cacggattca
    72481 tccgtcagag aaagaagaaa cgcccctcga ttgatccgta ccccgatcaa atattccttg
    72541 atactggtac ccatatgatt tttgaatact cgcgacaaat ggctccgatt gaccgctaaa
    72601 tgctgggcga tttcctcaac agacaatttt tcagcataat gtgcctcgat gtatttgact
    72661 gtttcaacag ctaaagagga atgaaccttt tgtacaccac cgctgacctt tccgccatct
    72721 tttaaaagga ctgataaaaa acggtaggtt aatgctgtta actgtaattc attttccaag
    72781 gtttcttccg tatctttcat gcattctaaa ataatgtcga tatatttttg tatgtcagaa
    72841 gagaccatcg tgtattggtc ttctctgaaa agcgactgcc gaatgatttc ttctgcagca
    72901 ctcccaccaa atgaaagcca gcaatacatc cacggatctt ctccatctga taagtaaaac
    72961 gtcgagtctc ctggacgaat caagaacaga tcaccttttt tcaattggaa ttgttgattt
    73021 ttcacatgat aagatccttt gccttccatc acgacatgca ggatgtaatc attgcgaata
    73081 gcaggaccaa aagaatgaaa cggcatcgtt ttagagaaac cacaaaaatc aaaatacaat
    73141 tctttttcta cttgttgatg ttcctttttt aaaaaaatcg attgctccac gtctatccct
    73201 ccttactcct ttagtataat gcaacaaaaa gttaaataaa agtcacagaa atatattaaa
    73261 aaggaagcga tttcttgtta agtttaagtc attaaaagat ctttgttatt cgttgtaacc
    73321 ggtttactta gtattatata ttgaacagga gaggaataca gattatgaaa agcaaaatga
    73381 tccaacgtgt gtcctacgct ttaggcgctt ttggacacga cacattctat gttacattaa
    73441 gcacttattt tatggtattc gtgacaagcc agatgttcgc aggaacagat aaggcaacga
    73501 atgcaaaaat gattgctaca gttacaagct tagttgtagg tatccgctta gttgaaatta
    73561 tttttgatcc tttgattggt ggcatcatcg ataatactcg tacaaaatac ggtaaattca
    73621 aaccatggtt agttatcggc ggcgttgtta gttccgtact cttggtagca atctttacca
    73681 atttctttgg cttagctact cataatacga ctttatttat catattattt gcaatcgttt
    73741 tcatcttatt ggatagtttt tattcattta aggatatcgc tttttggtca atgattccag
    73801 ctttgagtac ggaaacaaag gaacgtgaaa aatttgctac gtttgctcgt ttcggctctt
    73861 ctctaggtgc aaatggtact actctagtcg ttgtccctat cgttactttc tttacctatc
    73921 ttgttactca taaacatatt gaaggcgctt caggctggtt ctggttcggt gtgattgctg
    73981 ctgttatttc aggcggtact gcgattatca ctgccttggg cacaaaagaa gtcgatactg
    74041 cgatccgtca gcaaaatgaa aaagctggga tcaaagatgt gttcaaagca gttgctcaaa
    74101 atgatcagtt gatgtggctt gcccttgctt atatcgctta tgcgattgcc aatgcagcaa
    74161 caactgccgt attattctac ttcttcaaat atgtacttgg ccaaccaact gaattttgga
    74221 tcgttggtct agttgctgcc ttacttggtt tagtagctgt tccactattc ccaatgctta
    74281 cacgcgtcat ctctcgtcgc tacgtttacc ttggagggat cgcaatgatg atttcttctt
    74341 actttttctt tacgatcgca ggttcaagtt tgccaatcgt tatcatcggg ctagtattgt
    74401 tctacttccc tcaacaattg attttcttat ccgctttgat gacgatcaca gactctgttg
    74461 aatatggtca atggaaaaat ggtatccgta acgaagctgt tactctatca attcgccctt
    74521 tactagataa aatcgctggt gctttgtcta acgggatcgt agggtttgtc gctatcgctt
    74581 ctgggatgac tggtaatgct actgctgctg atatcactgc tcatggcgta acgactttca
    74641 aagcttatgc attctatgct cctgctgctt tgatgatttt ctccgctatt atttttgctt
    74701 ggaagattac attgacagag aaaaaacatg cacaaatcgt tgagaaattg gaaaacaaat
    74761 tggctccagc tgatacaatg gaagatgaac ttcacgatgc agtagatcct tcccattaag
    74821 aaaggatctt gaaaatgaag attacagaaa aagattttgg ccaaggttat cacttgataa
    74881 ccttggagaa caaaaacaag ctagcacttt ctatctctga tttaggtgct agaatcgtca
    74941 gtttaaaatc aaatgatcga gaattagttt tgggatttga caccgctgaa gaatatatcg
    75001 aaaaagatcc gtatatcggt gcttctatcg gtcgcaccgc agggagaatc gaaaatggcc
    75061 gcttttctct caatggaaaa acttaccaat tagccacaga tccaaaaact ggacataatc
    75121 tgcatggtgg tgctcctgga tttgaattaa aaaaatggtc ttatgtcatt ttgaatggcg
    75181 aaaatgaagc ttctgtcatt tttactacta caagtcccga cggagaacat ggttttccag
    75241 gtacaatgga tgtggaaatc cgctatactt tgacaaaaga taatatctgg cgagtgacct
    75301 ctcgcggcac cagtgaccaa gatactttat tcaatccgac aaatcatgtt tacttcaact
    75361 tgacgggaga tgcttctcag tcaatcgatc aacatgagct ttggctcaat agcgaagctt
    75421 atgctccttt gcgaacagat agtattccta taggggtaaa agaaaatgct gcaggaagtg
    75481 ctttcgattt tcaaatacct aaaaaattag cgtccgtttt tgctagtgat ttggatcaaa
    75541 aaaatcttgt tgacggaatc gatcatccat ttttcttaaa agaaaccggc ttgggtaaag
    75601 aagccgctcg cttgactagc cccgataaaa gaatccaagt agatattgct acagatgctt
    75661 ctagtgtggt tattttcact gcaaatttcg gcacagaaac accagaaatg cgcaaccgaa
    75721 aactggcaca tcacggtggc atcacatttg agactcaaac agctccaggt gcagagcgct
    75781 tctcagcatt tggttcgatt catttaaaag ccggatcagt atttgaaaca gtaacagaat
    75841 tcaaaatcaa aacaagaaag gaataactca tcatggaaat caaaagaagc ttaaacacaa
    75901 aatttgccga aacattcgga cctaaaaaaa ctacacaata cttctcacca ggacgcatca
    75961 atttgattgg tgaacacaca gattacaatg gaggccatgt cttccccgct tccatcactt
    76021 atggaacgca aggtgtagca gcacctcgag acgataataa aatattagtt tattccacaa
    76081 actttgacga tatcggtgtc attagtttta ctttagatga gctagaatat gataaaaaag
    76141 caaactgggc aaattacgta aaaggaatgg tccttaaatt aaaagaagct ggacactcaa
    76201 tcgatcatgg gtttgagtta ttagtggaag gaacaatccc taatggtgca ggactttcca
    76261 gtagcgcttc attagaatta ttagtaggtg ttgtattaga agatctgttt gatttaaaaa
    76321 cagatcgctt ggaactagtc caaacaggta aaaaagtaga aaatgaattc atcggtgtca
    76381 attcaggtat catggatcag tttgccatcg gcttcggtga gctagatcat gcaatcttat
    76441 tagatacaaa tacgctgaaa tacgaaatgg ttccagtgaa actagatggt tatgcaatcg
    76501 tcatcatgaa tacgaataag cggcgggaat tggcagattc aaaatacaat gaacgccgta
    76561 gcgaatgcga agaagccttg gcacgtttgc aaaaaacttt gcctatctct tctttaggag
    76621 acttagatga agaagaattt gaatcaacta ttgaccaaat cggcgatgat acattgatac
    76681 gcagagctcg ccatgccgtt tctgaaaatc agcggacttt gaaggcaaaa gctgaattag
    76741 aagctgggaa cttagaagca tttggtcaac tgttaaatga ttctcaccac tctcttcgct
    76801 atgattatga agtaactggg atcgaattag atacactagt agatgctgct caaaaacaag
    76861 aaggtgtctt aggtgcacga atgacaggag ctggatttgg tggctgtgcg attgctcttg
    76921 tcaaagaaga aaatatacct gccttcaaaa acaatgtcta tgatgaatac atgaaagttg
    76981 tcggctatgc tccggaattt tatgttgcac acattggaaa tgggacaaca aagatcgatc
    77041 cagaagctgt tcatgtttga taaaaaaatc aacgatctca gctaaaaaca aatagataaa
    77101 aataacctct cagcaatttc caaatgtgag ccttttgctc gtatttgaaa attgctgttt
    77161 tttattgaca cggaaagaga acgtgtgttc taattgtgtt gaagaggtga ttgttatgtg
    77221 ggcgaatcaa aatccggtat ttgtttatga aaaagaacct tcaagagata ttttatgtat
    77281 tgactgcaaa tctttttacg cctccgtaga gtgcgttgaa aaggatcttg atccccttac
    77341 aactaaatta gtagtcatgt cctatccgtc cgattcgaca gaaacacggg gtagcggatt
    77401 aatcttggct tccagtcctg cagcaaaaaa agcttacggc atcaccaata tcagccgtgc
    77461 cagagatctt cccttcccct atccaagtga tttatatatt gttgccccaa ggatggccta
    77521 ttatatggaa aagaacagag aaatcaattc tatctataaa aaatatgcag acgaagcgaa
    77581 ccatcatgtc tattccgtcg atgaaagctt ccttgatgta acaaatagca tggcactctt
    77641 tggtaaaaca aatgcgtacg acatggctaa actgatccat aaagatgtgt ttgagcagac
    77701 cggaatctac acgactatag gaattggcga taacccgcta cttgctaaac tagccttaga
    77761 caatggctca aaagacggaa agcaaatgtt tgctgaatgg cgttatgaag atgtaccaga
    77821 aaagttatgg aaaatctcag atatcactga cttttgggga atcggcaaac gaacagcaaa
    77881 acgtctgaaa caaatgggta tacattctgt ttatgattta gctcacgcgg attattatca
    77941 cttgaaaagc aagctagggg tcatcggtac tcagctttat gcccatgctt ggggcatcga
    78001 tcgaagtttt ttgggacaag aatatacacc aaaatcaaaa agtatcggaa atagtcaaat
    78061 cctagataga gattatacaa gacgagaaga aatcgagatc gttatcaaag aaatggccga
    78121 ccaagtcggc actcgcttga gacgatctgc agcaaaaaca caagtagtca gcttatgggt
    78181 aggatactct ttaggctatc ttgatccaaa tggcaagacc gggtttcacc agcaaatgaa
    78241 aatcgaagcg acaaatgcta gcagagatct agcagatgct ttattgacca ttttccacca
    78301 gcattaccac taccaggata ttcggcgtgt aggcgtgaac tgttccgacc tcgtatacgc
    78361 gacaggttta cagcttaacc tttttgaaga tcctgaaaag cagataaatg aagcgaaagt
    78421 tgattttgtt gtcgatacga ttagaaaaaa atacggcttt caatcaatca tccatgcgca
    78481 tagtctcttg caaggaggac gcgccatcgc acgtagttct ctcgttggcg ggcatgcagg
    78541 tggtatgagt ggattagaag gtggaaaaga tgagacggac agcaaaaaaa ttcattgact
    78601 ataacgagta tcgagatcgg ccatttggat taaaatgggg gactgctttt gcgatggaag
    78661 aactagtcaa cggtatcaaa aaaatgaaga agaagcacgc aaacagcctc ttcctaaaca
    78721 acaaatgaca ttgcaagaaa tcgatagtat actgacagaa gcctttttat ctcgtaaagc
    78781 agtaatcatt cagctcaatt taaaagatga atttggaaga ctcttggatg aggtcgaagg
    78841 gcacttcatt ggtgaagcct atgaagatta ctttatgatt gaccatcagc cgatattgtg
    78901 ggaagacgta cggtatattg agttaaagga aacaaaaaaa tggtttgtga catgagaggt
    78961 tgtgacagaa gtgatcaact tcaaaaaata agaaaggatt tttcgaaaat tgcttcttaa
    79021 atttttgtgg aattttggct tatttttcga agaagcaact tctggaacaa cgtatattag
    79081 atatcagagg ttgtgaaaaa gtcgcttagt tttgagtaac aagccaaggc gctgatttca
    79141 caacctctgt ctatctatcc atctattcgg taagattcat gcatgacgtc ttctttattt
    79201 agtatgtaga gccctttttc ttctgaccat tcaacataaa tcagctgttt tacatctgca
    79261 tagccttctt tcttcaagtt ctccataagc catgcttcag tcaattgatt ggactgaagc
    79321 actttatgct gaatttgccc ttcatctaca agcaggatcg ataaagcttt gtcttcatct
    79381 gattttttca atacactcat ttgaccggca ttctctagga taacatgttt ggcattttca
    79441 agaaaaaagc attcttgctg tcttaagatt gctcgcaact gctccatctc gatatggtta
    79501 tttgtcaact ctgtcatgtt gatgacgccg tctttgatta gaacagatgg ctcgcctttg
    79561 acccaacgat tgaccttttc atttttttgg acgatacgtt cgataccata aatcattact
    79621 gcccaaagcg caatggcaaa taggacatgc cctacatgga cattgtcatc ataggttgat
    79681 tcttctaaga tcccacctaa aacaagcgta tagactaaat caaacggtgt gatttctgac
    79741 atggatttct tcccaagcaa acgtaccact aataataaac cgatcaaccc gaacaccagt
    79801 ttcattgtaa ttgaaaaaat cattttttct ccccctaact atctgttaat taaattatat
    79861 atgctttctc acgaacacgc atggaatata caaggaagaa atgtatcctt ttactaaaaa
    79921 aaggactgtg acactgtagt gacccccaaa agttagactt ttttggagtg gagaaatcca
    79981 ctcctttttt ttatgctcta aaatgatatt tttacacaac cgttacggtt gttttacgaa
    80041 attggacg
//
LOCUS       DAFENC010000009        78712 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.009, whole genome shotgun sequence.
ACCESSION   DAFENC010000009
VERSION     DAFENC010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 78712)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 78712)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..78712
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.009"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(1015..1305)
                     /locus_tag="LP493_000803"
     CDS             complement(1015..1305)
                     /locus_tag="LP493_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132969.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            1707..1943
                     /locus_tag="LP493_000804"
     CDS             1707..1943
                     /locus_tag="LP493_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132970.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            1950..3902
                     /locus_tag="LP493_000805"
     CDS             1950..3902
                     /locus_tag="LP493_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HBL2132971.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3974..4471)
                     /gene="dfrG"
                     /locus_tag="LP493_000806"
     CDS             complement(3974..4471)
                     /gene="dfrG"
                     /locus_tag="LP493_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HBL2132972.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(4798..5490)
                     /locus_tag="LP493_000807"
     CDS             complement(4798..5490)
                     /locus_tag="LP493_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBL2132973.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
     gene            5885..6508
                     /locus_tag="LP493_000808"
     CDS             5885..6508
                     /locus_tag="LP493_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL2132974.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQP
                     VVQETVQTEKQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYI
                     GRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(6592..7314)
                     /locus_tag="LP493_000809"
     CDS             complement(6592..7314)
                     /locus_tag="LP493_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBL2132975.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(7304..8041)
                     /locus_tag="LP493_000810"
     CDS             complement(7304..8041)
                     /locus_tag="LP493_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2132976.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            complement(8053..9045)
                     /locus_tag="LP493_000811"
     CDS             complement(8053..9045)
                     /locus_tag="LP493_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL2132977.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            complement(9060..9803)
                     /locus_tag="LP493_000812"
     CDS             complement(9060..9803)
                     /locus_tag="LP493_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2132978.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     regulatory      complement(9877..9981)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(10044..11366)
                     /locus_tag="LP493_000813"
     CDS             complement(10044..11366)
                     /locus_tag="LP493_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBL2132979.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     gene            complement(11353..12318)
                     /locus_tag="LP493_000814"
     CDS             complement(11353..12318)
                     /locus_tag="LP493_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2132980.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            complement(12315..13853)
                     /locus_tag="LP493_000815"
     CDS             complement(12315..13853)
                     /locus_tag="LP493_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HBL2132981.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            complement(14269..14556)
                     /locus_tag="LP493_000816"
     CDS             complement(14269..14556)
                     /locus_tag="LP493_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132982.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            14690..15358
                     /locus_tag="LP493_000817"
     CDS             14690..15358
                     /locus_tag="LP493_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL2132983.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            complement(15649..16389)
                     /locus_tag="LP493_000818"
     CDS             complement(15649..16389)
                     /locus_tag="LP493_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132984.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(16519..17466)
                     /locus_tag="LP493_000819"
     CDS             complement(16519..17466)
                     /locus_tag="LP493_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2132985.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            complement(17595..18359)
                     /locus_tag="LP493_000820"
     CDS             complement(17595..18359)
                     /locus_tag="LP493_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBL2132986.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            complement(18363..18752)
                     /locus_tag="LP493_000821"
     CDS             complement(18363..18752)
                     /locus_tag="LP493_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132987.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            18887..19429
                     /locus_tag="LP493_000822"
     CDS             18887..19429
                     /locus_tag="LP493_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HBL2132988.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            19577..20209
                     /locus_tag="LP493_000823"
     CDS             19577..20209
                     /locus_tag="LP493_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2132989.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(20343..20468)
                     /locus_tag="LP493_000824"
     CDS             complement(20343..20468)
                     /locus_tag="LP493_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2132990.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(20602..21495)
                     /locus_tag="LP493_000825"
     CDS             complement(20602..21495)
                     /locus_tag="LP493_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HBL2132991.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(21677..22603)
                     /locus_tag="LP493_000826"
     CDS             complement(21677..22603)
                     /locus_tag="LP493_000826"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HBL2132992.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(22688..23449)
                     /gene="pflA"
                     /locus_tag="LP493_000827"
     CDS             complement(22688..23449)
                     /gene="pflA"
                     /locus_tag="LP493_000827"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HBL2132993.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(23693..25924)
                     /gene="pflB"
                     /locus_tag="LP493_000828"
     CDS             complement(23693..25924)
                     /gene="pflB"
                     /locus_tag="LP493_000828"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBL2132994.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(26201..28651)
                     /gene="parC"
                     /locus_tag="LP493_000829"
     CDS             complement(26201..28651)
                     /gene="parC"
                     /locus_tag="LP493_000829"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HBL2132995.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(28663..30708)
                     /gene="parE"
                     /locus_tag="LP493_000830"
     CDS             complement(28663..30708)
                     /gene="parE"
                     /locus_tag="LP493_000830"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HBL2132996.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(30874..31308)
                     /locus_tag="LP493_000831"
     CDS             complement(30874..31308)
                     /locus_tag="LP493_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HBL2132997.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            31435..32073
                     /gene="plsY"
                     /locus_tag="LP493_000832"
     CDS             31435..32073
                     /gene="plsY"
                     /locus_tag="LP493_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HBL2132998.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(32205..33080)
                     /locus_tag="LP493_000833"
     CDS             complement(32205..33080)
                     /locus_tag="LP493_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBL2132999.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(33162..33953)
                     /gene="codY"
                     /locus_tag="LP493_000834"
     CDS             complement(33162..33953)
                     /gene="codY"
                     /locus_tag="LP493_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HBL2133000.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(33971..35371)
                     /gene="hslU"
                     /locus_tag="LP493_000835"
     CDS             complement(33971..35371)
                     /gene="hslU"
                     /locus_tag="LP493_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HBL2133001.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(35385..35933)
                     /gene="hslV"
                     /locus_tag="LP493_000836"
     CDS             complement(35385..35933)
                     /gene="hslV"
                     /locus_tag="LP493_000836"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HBL2133002.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(35970..36875)
                     /gene="xerC"
                     /locus_tag="LP493_000837"
     CDS             complement(35970..36875)
                     /gene="xerC"
                     /locus_tag="LP493_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HBL2133003.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(37073..38449)
                     /gene="trmFO"
                     /locus_tag="LP493_000838"
     CDS             complement(37073..38449)
                     /gene="trmFO"
                     /locus_tag="LP493_000838"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HBL2133004.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(38418..40496)
                     /gene="topA"
                     /locus_tag="LP493_000839"
     CDS             complement(38418..40496)
                     /gene="topA"
                     /locus_tag="LP493_000839"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HBL2133005.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(40618..41475)
                     /gene="dprA"
                     /locus_tag="LP493_000840"
     CDS             complement(40618..41475)
                     /gene="dprA"
                     /locus_tag="LP493_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBL2133006.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(41531..42298)
                     /locus_tag="LP493_000841"
     CDS             complement(41531..42298)
                     /locus_tag="LP493_000841"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HBL2133007.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(42291..43151)
                     /gene="ylqF"
                     /locus_tag="LP493_000842"
     CDS             complement(42291..43151)
                     /gene="ylqF"
                     /locus_tag="LP493_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HBL2133008.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            43411..43809
                     /locus_tag="LP493_000843"
     CDS             43411..43809
                     /locus_tag="LP493_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL2133009.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            44088..44588
                     /locus_tag="LP493_000844"
     CDS             44088..44588
                     /locus_tag="LP493_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBL2133010.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(44671..45222)
                     /gene="lepB"
                     /locus_tag="LP493_000845"
     CDS             complement(44671..45222)
                     /gene="lepB"
                     /locus_tag="LP493_000845"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBL2133011.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(45374..45601)
                     /locus_tag="LP493_000846"
     CDS             complement(45374..45601)
                     /locus_tag="LP493_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HBL2133012.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(45598..46116)
                     /gene="msrA"
                     /locus_tag="LP493_000847"
     CDS             complement(45598..46116)
                     /gene="msrA"
                     /locus_tag="LP493_000847"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBL2133013.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(46136..46849)
                     /locus_tag="LP493_000848"
     CDS             complement(46136..46849)
                     /locus_tag="LP493_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HBL2133014.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(46852..47748)
                     /locus_tag="LP493_000849"
     CDS             complement(46852..47748)
                     /locus_tag="LP493_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBL2133015.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(47906..48748)
                     /locus_tag="LP493_000850"
     CDS             complement(47906..48748)
                     /locus_tag="LP493_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBL2133016.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            48880..49533
                     /locus_tag="LP493_000851"
     CDS             48880..49533
                     /locus_tag="LP493_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBL2133017.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(49596..50123)
                     /locus_tag="LP493_000852"
     CDS             complement(49596..50123)
                     /locus_tag="LP493_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBL2133018.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(50143..51090)
                     /locus_tag="LP493_000853"
     CDS             complement(50143..51090)
                     /locus_tag="LP493_000853"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HBL2133019.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(51102..52988)
                     /locus_tag="LP493_000854"
     CDS             complement(51102..52988)
                     /locus_tag="LP493_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBL2133020.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            complement(53148..55226)
                     /locus_tag="LP493_000855"
     CDS             complement(53148..55226)
                     /locus_tag="LP493_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBL2133021.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            complement(55239..55514)
                     /locus_tag="LP493_000856"
     CDS             complement(55239..55514)
                     /locus_tag="LP493_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133022.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(55876..56331)
                     /locus_tag="LP493_000857"
     CDS             complement(55876..56331)
                     /locus_tag="LP493_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133023.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(56485..57693)
                     /locus_tag="LP493_000858"
     CDS             complement(56485..57693)
                     /locus_tag="LP493_000858"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HBL2133024.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(57805..58137)
                     /locus_tag="LP493_000859"
     CDS             complement(57805..58137)
                     /locus_tag="LP493_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBL2133025.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            58285..59160
                     /locus_tag="LP493_000860"
     CDS             58285..59160
                     /locus_tag="LP493_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL2133026.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(59242..59823)
                     /locus_tag="LP493_000861"
     CDS             complement(59242..59823)
                     /locus_tag="LP493_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HBL2133027.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(59829..61088)
                     /locus_tag="LP493_000862"
     CDS             complement(59829..61088)
                     /locus_tag="LP493_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBL2133028.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(61090..62136)
                     /locus_tag="LP493_000863"
     CDS             complement(61090..62136)
                     /locus_tag="LP493_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133029.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(62371..62646)
                     /locus_tag="LP493_000864"
     CDS             complement(62371..62646)
                     /locus_tag="LP493_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBL2133030.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(62889..64199)
                     /gene="der"
                     /locus_tag="LP493_000865"
     CDS             complement(62889..64199)
                     /gene="der"
                     /locus_tag="LP493_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBL2133031.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(64381..65610)
                     /gene="rpsA"
                     /locus_tag="LP493_000866"
     CDS             complement(64381..65610)
                     /gene="rpsA"
                     /locus_tag="LP493_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HBL2133032.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(65745..66425)
                     /locus_tag="LP493_000867"
     CDS             complement(65745..66425)
                     /locus_tag="LP493_000867"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBL2133033.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(66474..67109)
                     /locus_tag="LP493_000868"
     CDS             complement(66474..67109)
                     /locus_tag="LP493_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL2133034.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(67175..68578)
                     /locus_tag="LP493_000869"
     CDS             complement(67175..68578)
                     /locus_tag="LP493_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HBL2133035.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWGTILLNLFKKNMEH"
     gene            complement(68565..69596)
                     /locus_tag="LP493_000870"
     CDS             complement(68565..69596)
                     /locus_tag="LP493_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2133036.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            69627..69848
                     /locus_tag="LP493_000871"
     CDS             69627..69848
                     /locus_tag="LP493_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBL2133037.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(70013..70750)
                     /locus_tag="LP493_000872"
     CDS             complement(70013..70750)
                     /locus_tag="LP493_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HBL2133038.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(70903..72243)
                     /locus_tag="LP493_000873"
     CDS             complement(70903..72243)
                     /locus_tag="LP493_000873"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HBL2133039.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(72480..74003)
                     /locus_tag="LP493_000874"
     CDS             complement(72480..74003)
                     /locus_tag="LP493_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HBL2133040.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(74381..74992)
                     /locus_tag="LP493_000875"
     CDS             complement(74381..74992)
                     /locus_tag="LP493_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBL2133041.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(75115..75240)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(75322..76038)
                     /locus_tag="LP493_000876"
     CDS             complement(75322..76038)
                     /locus_tag="LP493_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBL2133042.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(76044..76613)
                     /gene="scpB"
                     /locus_tag="LP493_000877"
     CDS             complement(76044..76613)
                     /gene="scpB"
                     /locus_tag="LP493_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HBL2133043.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(76597..77394)
                     /locus_tag="LP493_000878"
     CDS             complement(76597..77394)
                     /locus_tag="LP493_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HBL2133044.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(77364..77735)
                     /locus_tag="LP493_000879"
     CDS             complement(77364..77735)
                     /locus_tag="LP493_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBL2133045.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(77754..78641)
                     /gene="xerD"
                     /locus_tag="LP493_000880"
     CDS             complement(77754..78641)
                     /gene="xerD"
                     /locus_tag="LP493_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HBL2133046.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
BASE COUNT        22044 a        16376 c        13359 g        26933 t
ORIGIN      
        1 catacttgca aagtaatact acaattccta acataatcgt agaatttaat aatttccata
       61 gcataaagtg tttagaaaag aacattaaga atagttctat aataattctt gaactccatg
      121 tcttataatg ttctatcgaa gcacccaaat agccaagttc atctaatcta cttgcataaa
      181 ctacgtcatc cgctctcata gtcggcatat acatattaaa gagtaaaaag ataccccaaa
      241 tccctattag taacaagatc agttctttgt tattcgttat ttttctatta tgtttgttca
      301 tttttatact ccttcttata tttcctaata gagtataaca tagctttaag cattacttaa
      361 agataactta aaagttatct tttaaatact taattgttaa ataccttatt tgatgcaaaa
      421 gaaatctacg atagtcaaca aaaaaatttt cattatatcc agaaaaattt ttcttagtta
      481 aggacctatg gattgcagta atgcagaatt cgtcgaataa actgccaaag acatacaatc
      541 atattgcttt taaaattgac gaacaagata tagattcgtt tgtctcaaaa atccaaatgt
      601 taggtttaac tgtcgaacca ggacgttctc gtgtgaaagg cgaggcttct tcaatttact
      661 tttacgacta tgataatcac ctcttcgagt tacataccgg tactctccag gaacgtttaa
      721 aatcctacaa ttccactacc tgagactagt aatgactagt ctctttttat ggcctctgat
      781 ccccccattg agcgaatact aatagggctt cgaattgatc tgttcaatct ttaagcaata
      841 tccctcaaat gagtttggaa agtttagtga ttcatcacaa atacttaaat acatgtagtt
      901 atatatagat tgaggttctt gtgagcgtat gctcgtgtgg gttcaaatcc catcgtctgc
      961 atccatcttt ccaaaacaag cggctaggac atttttgtct cagccgcttg ttttctagtt
     1021 tattctttca tcttgtcgga ccttttttct tgggtataga cttttctcat attctaccac
     1081 aattttgggt ttccctaaca catgatagga tctcacaaca aattgctttc tattattata
     1141 ataacctgta acgactaact tcatcccttc gtctacttca gctaggaagt tcaaactatg
     1201 ggaagcaatc aaacaattga ccccatttaa actgaaacgg atcaacggtc tggcactaac
     1261 ttgcaaagta cggatcttat ctactgttcc atattttttc tccataacct tcacctcaat
     1321 accattatac gaacatacat tccctttgta aagaagaaac tctgttttat ctttttgact
     1381 ttttgtctat tacctttctt aaaatcatat tggcacttcc tgcgaagatg aaggacatgt
     1441 actaaaaaaa agaggcagca gtatagattt aagtagttca gttttggagt acaaaaagtg
     1501 aaaatgtaaa cctaaatgag tatcaaattg caactgaatt tgatactcgt tttttattgt
     1561 taaatcaacg tttgttgtta atttacacca caaaatgtaa gttaaaatgt atataaaaat
     1621 gcgaacgtga aataattatt gtaggaatgc aaattggtgt gttaaaatgg ttacaattta
     1681 ctaagcaaaa aggggtgcat tttcctatgc aatttcttga gccaaaaaat aagaacgcta
     1741 agtctgtgga ttgggaaata tcagagcaag taagggtgat agttaagcaa tacgctgaat
     1801 atgcagagcg tactgaaagc gaagcagtgg atgaattctt attgaacatt ttagacgata
     1861 agaagtttat tgaatggatt gccaacaagc gaagtaataa gcggattgtt gaaaaaatgg
     1921 gtatcaaaga tagagtgggt tgatagacaa tgaccaagct taaaagatta gccacgaagg
     1981 aagatgaaat tgtagatgtt aaaattccga tttcaaacga agaattaaaa gatagggcta
     2041 aacaatatga tttattaact ccaaaacgat ttgcaacaag gtataacaaa atgttgttct
     2101 tgccaacgtc ttttaaatgg aacggttctg aatatcccat tcaatataat tactgcatca
     2161 atccgttttg ttgtaatttt gggaaagaac agcacaaatt caaagatgta aaagggaaac
     2221 caagtcgata taaaatgact ggtagttcca aagataaagg tcataaaggt atgtactgca
     2281 atgacaatcc tattggcaga ggtgtatcgc aaaactgtac agtaacccct ttatctaatt
     2341 ggtctgttgt tgaagaaatt aaacgcctta tagaaatcaa tagcatccaa gatgttgagc
     2401 cagattatca atttcataaa gaaggctgct cggaagaaga atcaacccca ttcaatgagc
     2461 cgaagcaatt ttacaaaagg gggaaaagta ggggcaaatc tcaacgctat caatgtaagg
     2521 cgtgtaagaa gttcactaat gttctaccaa aaagagaaga aaccactact tatcaccaac
     2581 aaaagaacac cattcttcca atgttcgcta agatggttgt tggaagggtt tcagtcagtc
     2641 gtacttgtga tattttagga attggagttg gaacctacta tcataagctg gagtggctgt
     2701 ataggcgttg tttggagttt ttagaacgat atgagacaca accccttcaa acaaagaaat
     2761 ttaacgagat gtggcttaat acggacaaga tgcactacta cctaaataac gtccgtaaga
     2821 aaggacaagg ttcaaagaaa tatacggggt ttgaagacct taatatgcaa acgtatatag
     2881 ttgtatctgc tgaggtctta tcaagatatg tgttccgttc tgatgttgcc tatgattgga
     2941 atatttcaat ggatgaatta aatgaagata caagaaaatt caaagaagac catctcaata
     3001 cttttagtcg taaaaatgat aggttagatt ggtcttatta tccacaagaa ccatccgcta
     3061 acgatagcga aaataggaat gcttatcttc acgaattagg gaaaattact aataggagta
     3121 gatttgtcga tggtttaaat gttgatgctc cttatactac aactgctcac tattggttaa
     3181 ttaaacaaat ggttaatgcc gacgaatggc gaatgattag tgatgatgac ttctctatta
     3241 gaaacgcctt ttatagagta ttcacgaaag aattaaggtt gagcgatgca catcatttta
     3301 tttgccaagt taacaagacg aaaagcagaa aacaatgctt aaaagaattc ggacaagcaa
     3361 aagcagaact gctcgattgg ggagatatca gaggattcaa aacaaagttt ctacggactt
     3421 tggcatctca ttatctaact gaattactaa caagtcatca attccacgaa gaggctatta
     3481 gtaaagatgg agaaagatat cgcaaatatg ccgataaccc tatcaaacat ccattagcca
     3541 ctaaggataa aggattttat tcagttgatt gtagaacgga tttatctgct ctggaaccaa
     3601 acgaaatcgc aaagatgcta ttaaatgtta atgaccattc gaccaatagc tttattcaac
     3661 agataagacg ttatatatca tctcttgaaa gaccattaac aacagctcgt ggtgataaga
     3721 agagctatat ttacgctaac ttcaatccga agtatgctca atttgcgatt acaattctaa
     3781 gaacttacta caacttttgt cgccctttta aatcagcgga taaaaaggtt ttgacacctg
     3841 ctcaaagatt agggattaca gataaacaat ttgattggaa agatataatt tatttcaaat
     3901 gacaaaaaga gcttggagta atcccaagct cttgtgcttt atctttactg ttcttcttca
     3961 attaacgcac ccgttaactc aataagtttt ttctttcata tacatgaaaa tagtagttat
     4021 acggattttt atcattcttt atcccttttt gggcaaatac ctcattccat tcctcataat
     4081 tcacttctgg aaaaaaagta tctccttcga attcatgatg tatttttgtg atgtacattt
     4141 tctcaacata agggaaaaac aaattataaa tctgttctcc tccgaaaata aaaatttctt
     4201 cttcgttttt acataactca aaaacatctt ctattgaatg aacaatttca caaccattaa
     4261 aggtaaaccc cttatctctc gtcagaataa tatttcttct gtcaggtaag gctcttccga
     4321 ttgattcaag gttcttccta cctaatatta tcggatgtcc ctttgtagta tttttaacat
     4381 attcccagtc cttgggaatc ctccaaggaa tgtcattctc tttgccaatc actctattct
     4441 tatccatcgc agcaatcaaa gaaactttca tttataacac agccttttta actaatttac
     4501 catctaattt cttatttcta tcaaaaaacc ttttctcatt atcctgcccg ttagttgaat
     4561 aagcaatttt ttctataagt tatattatca taataccaca aaatcacaaa ttttcattca
     4621 attatcattt tcaattgcat tttataaatc attttgtatg taatttggta tgtaagttaa
     4681 aatgaaaaaa gtagtccatt ttgaagtaca ttttgtcatt ttgtactcca aaactgaact
     4741 acttagtata gattactgtt gcttctttac taatttaggt ttacttgtta agaaagatta
     4801 tttacgcaaa tgttcttcaa caatttgctg agatttatca gctgtatctt ccacttcatc
     4861 ttttgctttt tctaactttt gaatatattg tttcaagctt gagttttcag cagttgcttc
     4921 gtctaatttc ttttgtgtat ctgttaactg agtttctaca tttgtttttt cttgtgtcag
     4981 tgttgcgatt tgttgattca aaccatttac agtattttgt aattctgaaa gttttgcttg
     5041 tgcttcttgt agtcttgctg tccaatctgc attcagatga ttgatttcat catttttttg
     5101 gttgatctca tctagtttga cattgatttc attttgtttg ctttgtagtt gtgcatcctt
     5161 gctgactaat tgactttcta agttttgttt ttctgctgcc gattgatttt tttggttttc
     5221 taattcattt acttttgttt ggtattcttg gacatctgcc tttgaatctt gcaatgtctg
     5281 ttctttttgt gctagtcgag cggtaagatc tgtaatcgct tgctctttat ctgtcaatgt
     5341 atgatcaagc tgtgtcagat tctcattgat tgtatcaata tctgtctctc caccccacaa
     5401 aataatttca tttgcgtacc gcgtgcctgt gtagccaatt agacatagaa atgcaacgac
     5461 aatcccacca gtaataaatt tctttttcat ttgcatagct ccttaatcca atacttttac
     5521 atgctaaaag taagtgatct caaacacaat gtcaagcgtt tttaaattac atatgtaatt
     5581 ttaatataaa tactatcaaa tactcattta atcctccttt tttatctatt taaaaaatct
     5641 tttttataga gaaaaatgca ggttaatact ttcttaaata aatatttatg gtgaacaaaa
     5701 acaaaaaagc aagttttatt aaacgtaacc cttttcattt catagattac tgtatttatt
     5761 acaaaaaacg cggatttgtc ataaattgtc atgcttcttt tacctatgaa atattttcac
     5821 gtgttaaagt attcctcgtt gaacacaaca aataaaactt tttaacgaat aaaggagatt
     5881 tttcatgaca tcacttaaaa ctttactttt tggaacaact ttggctgccg gcgctgcatt
     5941 cttcatggga acgactgctc atgcggacga agcttatacc gttcaatcag gtgatactct
     6001 atcaacgatt tctcaaaaat acgttggtga taactccttg atcaatgcca ttgcagaatc
     6061 aaattcaatt tctgatatta acctgattta ctcaggacaa caattaacaa tcccaacaga
     6121 aggctctgca caagcagctg ctgaacctca agcagccgtt caagaagcac cagtccaagc
     6181 tgaacaacct gttgtacaag aaacggttca aacggaaaaa caagcagcgc ctgttgctga
     6241 aacacaacct gctcctgctg taacagaaac tgctgctact ccagcaagca caagctctgc
     6301 aaaagaatgg atcgcacaaa aagaatcaag cggttcttac acagcaacga acggacgtta
     6361 catcggacgt taccaattag attcttctta cttaaatggt gactactctg ctgcaaacca
     6421 agaaagagta gcagaacaat atgttacttc acgttatggt tcttgggaag cggcgaaagc
     6481 attctgggaa gcaaacggtt ggtactaaga ttcatttatt aatcaaacag tttactttta
     6541 tacaaagaaa gccaaaaaga ggtgcgacac tagttgtgtc acatctcttt tttatttacc
     6601 taatctaatg aaacgttcca agttttgata agtatttttt ttaacttctt caactgatag
     6661 ctctttgatc tcagcgattg tctttaactg ttcttcaagc agtgagacat aatctttttc
     6721 tgaaaaaatc ccccctaaag cccactctgc tgcatgtagt ccatccgttt caataagtaa
     6781 gtggtcgatt gggactgctt tagctagttg ccagactgct ggattctttt tcaaatcaag
     6841 accaatgctg aaataacagc ctaaatcaat atagtcttgt tgatagtcca aagaagaata
     6901 ccaatggatc aaatagtgat tagggtaagc ttggatataa tttaagatct ctttttcgca
     6961 tccttttgtg tgcagtacaa caggtttctc atttatggct gcaaaagcaa gctgtcgctc
     7021 aaatactttt ttttgtgtag tcatcggtac attcgtccaa atattatcta accctatttc
     7081 accgatgatc cttgcttttt tcaaaaaagg ctcaacttgt tcaaacgtat agctatctgc
     7141 tttccaagga tggataccgt aacttaaggc ttgagtctta cttgctgcaa gctgtctgtt
     7201 ttccttccat tcttctggcg aatcacaatt gatgatcgtc aaaatcgtgt gttcctgctg
     7261 aaggagtgct aaactctgac tcccatctaa atgacaatga gcatcactta acatctaatt
     7321 cacctgccaa taactgataa atcgtttgct tcaactctga ttgctgcagt agccattcac
     7381 gtgaccgtcg tttttcaggc acttgaatct cagcaatcac atgtgccgga cgggcggaaa
     7441 gcacaagaat cctgtctgat aaataaattg cttcttcgat atcatgcgtc acaagtaaag
     7501 tagtccgctt tgctttttta ggcagcttca acatccagtc ttgcatctgc cctctggtca
     7561 tagcatctaa cgctccaaat ggttcatcaa gaagcaagta agaagaagga ttcatgattg
     7621 ttcgtaacaa ggccgttcgc tgcttcatcc cgccagataa ttgttccggc aaaaaatgtt
     7681 catagccgtt taacccaaag atatccagat aatcccttac ttgttcttca ttgattgtta
     7741 gatgattgat tttttgatat aacgtaacgt tttgatagac gctcagccaa ggaagtaaca
     7801 tatcttcttg cggcatataa ctaaatgctg tatggagacc agttactttt tgatcgtcta
     7861 ctttgatcgt tccagaagtc ataggctgga ctcctgttaa agttttcagc aatgttgact
     7921 taccggctcc gcttggcgcg acaatcgatg taaaggtatc tttagggata gtgaaatgga
     7981 tgtcttctaa tattttcagg ttttcaatga ctacattcaa gtggctgatt tggattgaca
     8041 tatctatcac tcctatttta taaactgatt agtgaatagt tcttgcgaag gtacatcttg
     8101 cttgatcaat ccgttttcct gcataaaagc tgtataattg cgccaaactt tttcttccat
     8161 caatccccaa ttctcaggat catccgtata attttttgac aagaatgctt gtgattcttc
     8221 taaaaacgtc cgatcatttt cttttgcata tttttgcaac agtttagcac tgtcatttgg
     8281 atccttaata gcttcctgat agcctttttt cgtggcatcc ataaaagact gtaccaattc
     8341 tggatcactt ttgatcagtt gatcattcgt aataattacc ggagtatagt aatctaaccg
     8401 ttcatctaat tctttcaatg ggatatagtt tagttcaata cccgcttctt ttgctttgat
     8461 catatcccaa ccttcaaagt accattggat atctgaggat tttcctaagc tttctggccc
     8521 ttctccattg cttcctacca ttgtcagttt tgaaaagtcc ccgccgtctt tttccatcac
     8581 agcttttaag acagcttctt cacttggact ttgccaacct gcatatgttt ttccttcaaa
     8641 atcttttggt gaatggatgt tactgtctga tagggtggcg aatccagaag tattatgttt
     8701 gatcactgta gcaattgctt tgactggtat attctgtcca tctgcgtgag cataagtgac
     8761 atcttcttga taacttacac caaattgtgc tttgtccgca cctactagac caatacttgt
     8821 cgaattatct cctggttcga tgatttggac atttaaacca gcctctttat aatagccttt
     8881 ttcttttgct aggtagatgc cagtatgatt agtattcggt acataatcca aaacaagtgt
     8941 cacttttttc aaatccttta tttcttgttt gctacttgtt tcttttgcag tgccacaagc
     9001 ggataaaagc aacagtagcg gtaataaaag ccataatttt ttcatttgat ccccttctct
     9061 taaaaaatat aaagcatacg ataataccct tttttcaata atgaacaagc gccattcagc
     9121 aataaactca atagaatgac acaaatgatc gcagcaaaaa ctttatcgat ctggtagctg
     9181 ttttttacgc gtatcatgta ataccctaag cctgcttgag cgcttagcca ttctccaacg
     9241 actgctccgc tgacacaata agtagcagcc acttttaaac cggaaaagaa gccggataaa
     9301 cccgctggta ttttatatat tcgataaatc ttccctgtat ctgcccccat cgttttcaaa
     9361 aagatgattt gctcttttga tactttcctc aatgtatccg aaaaagaaac tacgatcgga
     9421 aaatagctta tcaagacaac aaggatcact tttggaagca taccgaaacc aaaccatagg
     9481 gtaagtaatg gccctaacac catgattggc aacatttgtg aaatcactag taacggataa
     9541 aaagacattt ctaaaaactt ccaataatcc attgccaagg cagtaataaa agaaagaacg
     9601 ctagctatta ccaaaccaag cactgcttca tttaatgtcg tgacagaatg ggaaagtaat
     9661 acttgtgcat ctgccgctaa tgcagaaaat acagcagcag gtccgggtaa aataaaggca
     9721 ggtattttcc aaactatgac aacaatctgc caaataatta aaatgaatgc catactgact
     9781 gctggataaa gatttttctt cattttgtta cctcctttct tctaatatga ataacaaaaa
     9841 acgcttgaaa tgggcacgac atagtaaccc gcttcaagcg tctgctatgt ttctcccttc
     9901 accagtatta actgacaggt tcaatgggtc taagttcaca acttactctc atgtcgtcta
     9961 cgacatcccc agaaacaggt attcattttt taaagtgtag cacaagaagg aaaaagcaac
    10021 aagcgcttta gttatcatgc tgattatttc aataaatagg agagatcact tgccaatgtc
    10081 ggatacccca tgatatagct atccaactct tttttagtca atttttgatt gatgacgagt
    10141 gtcaaatcat cgatcaattc gtctgcttgc tcgctaatca ctgcagcacc aatcaaataa
    10201 ttttgctggt caaaggtcaa ttcagcctta gcaactggtt cattgacacg atgataggtg
    10261 aaccaactgg taagatccat ctctaccact tgatctgacg aagaggcgtg actttttgta
    10321 actcctactt cagcaagttt aggactggcg tagacgatcg taggtataat cggatatttg
    10381 ataggttcgc ttgttgcatc cgttatccgc ttagctacat aatttccttc aaaagtggcg
    10441 actggtgtca attttggggt tttccttgaa acaatatctc cacacgcaaa aatttttgga
    10501 ttgctcgttt gcagataatc attgactgca attccgtgtt tatcaaagac gatattcgct
    10561 tgctcaagtg ctaaagattc tgtattcggc tgtctcccag tcgcacaaaa aatcatatct
    10621 gctactaatt ccgtctcttt tccgactaaa cgatagcgag taccttctga aatgatcttt
    10681 tgggtttcaa caccaaaagc aaactgaatg ccagatgctt ccatttgatg gacggcttcc
    10741 tctaccaaag acgcctcaaa ttcttttaat ggccgttgat tatgatggac aatggttact
    10801 ttgctccctg cagcattggc aatcgtagct agctcaaaag caatataacc accaccgata
    10861 aaaatgattt ctttaggcag tacaggcaat gataaaaagt ctgcactagt tttcaagtat
    10921 tcctttccct ccactggtaa gatcgtaggt ctttgcccgg ttgccaaaac taagtaatcc
    10981 gcatggaaga cttcttcgtt gacttcaata gatgaatcat ccaaaaaacg agcggttcct
    11041 gaaagatgat cgatttcagc ttctgctaat tgtttttttc ggctttctgg gactggatcc
    11101 gtaaatgttc gtttgaattt ttgaagttct tcccagttgg cagttgggat ctcgttaaaa
    11161 ccttttccac tcaattgttt tacccgatta cgtgcctcta ctgcacttaa caagactttt
    11221 ttaggatcac atccacggtt aggacaagtc ccgccccata gatcttcttc gaccactagt
    11281 actgttttac ctgcttcttt caatccataa gcagcactta agccgctcac acctgaaccg
    11341 atgatgattg catcatatgt tttcatttcc ttcctcctct cgacttaaaa aagcaaagat
    11401 ttctttactt gtcagcgacc caatacttct ttgcttttct actatcacaa tgcttggata
    11461 caccgaaaga agcgaatata cttctttcat aggcgtatca aagcaaactt gttgacgagc
    11521 attttctggt atttcattta agaaatatcc attgacgact aaatcttcta ctcgccactc
    11581 tttcgtctgt ttcggttcat caaagaaatg ccgaacgtag tcgtttttag gattcatcaa
    11641 taactgctct ggtgtgtcac attggataat ttctccatcc ttcataaatg caatacgatc
    11701 acctagcttg attgcttctt ccatattgtg cgtaacgaaa acgatggtcg tgcccaattc
    11761 ttcgtgtaag gacaaaacca attcttgtaa tgagtttctt gaaatcggat ctaatgcgct
    11821 aaatggctcg tccatcaaaa tcacatctgg gcttgcagca atagctcgga tgatcccgat
    11881 ccgttgctgt tctcctccag acaactctct aggcatacga tctcgataaa tatcaggaga
    11941 taagccaact ttttgaagaa gttcatctac acggtctgct cttttctgct tttcccaacc
    12001 taacatttca gggatgactt caatattttg cttgactgtc atggtcggga acaaagcgat
    12061 ttgctgcagc acatatccca tattccaccg cattttctgc agattatatt catttaacga
    12121 ttttcctttg aagtagatgt ctcctgctga tggtttagat aatccattga tcattttcaa
    12181 agtagttgtt tttccactac cggaaggacc aaccaaaaca aagatttctc cttttttgat
    12241 tgccagattt aggtcatcga tgacatactt tccatcatac tttttttgca catgtttgaa
    12301 ctcgattaat ttagtcactg atcttcctcc tttactaatc cttcattttt caggaagatt
    12361 cgtgctactt ctgtcggctt tttcttttcg acattgactt ggtaattcat atcaatcatt
    12421 tgatcctctg ttatttttcc gcttaattta ttcagtgctt taacgatttc aggatgttct
    12481 ttagcaaaat cttttttcat cagcggtgcg ccttgataag ctgggaataa ccctcgatca
    12541 tcttctagag tcactagatc gtactccttg agctggctat ctgtggaata ggcatccaca
    12601 atattgacat ctccattatt gattgcttgg taacgcaaac ttggctccat gctttgtaca
    12661 cttgaaaaat tcaagccata tgcttcttgg attcctttat atccatctga acgatcaata
    12721 aattccagtg tgaatcccgc tttgatctga tcagagatag ctgccaaatc ggaaatcttt
    12781 ttaagttgat gttcgttcgc aaaagatctc ttgactgcca aggcatacgt attttggtaa
    12841 gccattggtt ttaataatgt catatcgaat tgcttattca ataattcttc tgcttcgtca
    12901 tatgtttttt cttttgtcaa atcagcactt ttcattgctt caggtacctt caccaagctt
    12961 tctaggacag tacctgtgaa ctcaggatag atatcgattt gaccttgatc cagtgcattg
    13021 aacaaaaaac tcgtcttgcc aaaattcggt tttaattcaa cttctgtttt tgtgttgtct
    13081 tcaatcaatt ctttatacat ttggatcagg atttcaggtt ccgctcctaa ttttccagca
    13141 atcgtgatgg tttcattttt aaacaaggca gactgatata aagaaacgcc gccaaataaa
    13201 cacaccactg ctgctaaagt aatgatggaa tatcgaggtt tcttatgctg caaccagcga
    13261 atcagtccgc tgaatataat tgcaagcaag gcagaactga tcgcaccaat caatgtcaaa
    13321 acaggtgtat ttcggtcaat acctaacaaa ataaatgtcc ctaatccacc tgctccgatc
    13381 aatgctgcca aagtagccgt accgatgatt aaaactaagg cagttcggat acctgagata
    13441 atgacaggta atgcgatggg aagctctact ttcagcaagc gtctcattct ggacatacca
    13501 aatgctaccg ctgcttcttc aatagacggg tcaatttcag ctagaccaat atacgtgttt
    13561 tggaaaatcg gaagcaaagc gtaaataaca agtgcaatca atgctggaac agttccgatc
    13621 cctacaaatg ggataagtaa acctaataag gcaagtgaag gaatcgtttg gagcacaccc
    13681 gtgatctgca ataagacttc tgccattttt ttatgattgg ctgcccaaat cgctaaagga
    13741 atagcaatca gtgctgcaat cagcaaagaa atgagagaaa tggacagatg ttgaaatgca
    13801 gcttccagca actcgccttt tctttcactt aatgtttgta taaaattatt catgcgacct
    13861 tcctttctgt tattctttaa gtataaacat ttctttcctt tttcccaact aacttgtctt
    13921 gccttaacct tacagcacga acaaaaaaaa gaaaaaaata cctctaaata tgctgacaaa
    13981 aaaagaatcc aagcaacaaa gtcggatcaa ctttttggtt ctcgtttttt cactacgaat
    14041 accataaaaa tctatacgaa attgtcactt ggaatcagct atatcttttt tacacacaca
    14101 acttttattt taataaaaag aaacagccaa taaagtagaa atctcgtggg ggagaacacc
    14161 tttattggcc tgttcaacga atattatact gtatcatgac acttttttgc caaaaatgta
    14221 aaaaatggtt gttttgacat cataaacgtc ttgttttctt atttttactt atatcaccac
    14281 tttattttct atctctttca ctccataaag aggaatgagt tcttcttttg actgataata
    14341 aacagctttc tcacggttct tcatcaaaaa aagaaagatg tctttcatag caagtggtgc
    14401 tttgccgtgt tcaaataaaa agataaattg atttgcttta tttatctgga ccattgtcac
    14461 aggcaccagt ttttgttctt gagccaaaaa aactccttga tactctgttt ttttgggtga
    14521 ttttgtaaga attgtcaata agtctgctgc tcgcattttt ccactcctta tttgataaat
    14581 aaaaagaaac agccaaaaat aatttttttt cattttcctc ttgaagtaag agtataagtc
    14641 agtataataa agaagttgct gaaaattttc aaaagaaaag aggctagaaa tgaaaaaatt
    14701 aaatttattt acagaattgt gcggaatcat tttaggcgca ggaatctacg gattagctgt
    14761 gacaggaatc aatattccat ctaagctggc agatggtggg gttactggta ttgctttgct
    14821 tttgcataat ctttttggat tcgctccttc tgtcacttca ctgcttttta atttaccttt
    14881 attgcttatc tcattgtttc tttttggaaa acacgctttt ctccggacga tcgtcggaac
    14941 atttgcgcta gttttctttt tacatttatg ggagagcctt catatacatt ttgctgtaga
    15001 tagtctactg atcaatagtt tgatgacagg tattctttct ggcattggtt gcggtctcgt
    15061 ctttcgattc ggcggaagca caggcggaac agatatcatt tatcaagcca ttgaaaaata
    15121 ttttcatatt aagattggca aaagtctttt cttgattact tttggtattt tagttgtctc
    15181 cttgctttat ttggatctca cacattttct gtatacatta cttagctgtt ctattctatc
    15241 ttatacattg aataaagtga agtatctgga aattggatct gttttgcccc aattggaagc
    15301 aaaacagact acagaaacat ttgaaccact tgatcctctt gaacagttag agcactgatt
    15361 cttatttttc actactttat ttaatttaca gaaatatcat tatgtaaact aaaatgatat
    15421 tattcagtaa aatcttcttt ataaaaaaat aaactatttt tgcaaacgat ctgcgaaaat
    15481 agtttgtttt tttattttgc cattattttc ttacttattg ggagaaaaaa ttcgcttaaa
    15541 ctcaaaaaaa tttgaggata cgatataaac tttcggatag agtataaaat aaggaaacgc
    15601 cgcagcgttt cctttccaac tgtagccgaa tataaatttg tatatcactt atttaaaata
    15661 gctattttct cccaaagagt ttccttgatc atcgatcaat ccttgtaatg agcgttctaa
    15721 gataccatgg ctttttttcg attttttttc ttctgactgc tttgtttcct ctaacgtttt
    15781 tgttcgattg aatgttcgta cagacggctc accatttctt ttttcttgat acggcgtcgg
    15841 ttctgtatcg aacaacagat aagagtcatc cgtttttttc atcgattcga ttaaatgatc
    15901 ctcagaaatt ttgctttctc tagggtctgg gataatcgat gcgggtacat atttaggaac
    15961 aaaataagaa cgctcccgca ccttcgtgtc aacagatgcg tttcgtgtag tatgcttgga
    16021 ctctgtcctt gtttcacttt gtctgacaga acgagaggaa tcaccaaaaa gtttttttcg
    16081 tcctgtcgat gtgatttctg attggtaatg gccggtataa tccggtaatt ttcctttatg
    16141 cttttccaaa ttttccttac gcggagctga cttcaatcca tttgttgcac gacgcttgcg
    16201 acggattttc tcggtgttcg tgttcgtgaa atgaaattct ttcatctgtt caaacgggga
    16261 ctgattctgt tcagtcaaaa gatcttcttg tccgtcaaat aatactcgct tcttgtcgtt
    16321 ggttaatttt acgcctaact catcatcgta cgcaggaaaa cggaaatgtt ttcgtctgat
    16381 ttctttcatt caaaccatcc ttctcaaaaa tggaactttt ctcaataata gcacagattc
    16441 attgttttca gtagcaatgc gctgattatt ttaagaaaat agcgatgaat ttcataaata
    16501 tatatatagt aataagactt aattcgttgt ctctctgata actagttcag gaaaaaaacg
    16561 acgataacct tgactcgccc ctttttcttc tatttttttt aacaacattt ctccacatac
    16621 ttcacccata cgtataatat cttgcttgat cgttgtcaat ttaggtgaac tgatttggtc
    16681 taaaaatacc ccatcaaatc caatcacacc aaattcttcg ggcaagtgtc ctccagcatt
    16741 tataatccct cttactgctc ctagtgctag ccgatctgaa ctacatacaa aacaagtttt
    16801 atctgtaaaa tctgcccagt tttctgtcat atatctttct acttctgtcg aatgatttgg
    16861 aaaccgcaag attttactag gaagatcaac ttccttcatc acagataaat aaccagtttc
    16921 ccttgaaatt tcaaaaggct cgtccacttc gataccgata taaataatcg tttgataatc
    16981 tctttctaag gcatattgcg ttgcttttgc tgtaccatat tcattatcgc tgtctacata
    17041 atcatatcct tcagaatttt ccccaaacaa gacaactggt ttttccaaac ggtcgatcca
    17101 atcgaagtct ttttttctga cacctgtgat gatgtatcca tcacaagaac cgacgtcgaa
    17161 ggcatcattt gtaactaatt ggagagaata atgcgcttta ccgatccgtt tagcgattcc
    17221 catcagcaaa ttcatgtaat agggctcagt tgtgtcgatt tcttccagta taaataattt
    17281 gatgatctgc gaccgattcg tgacaagtgc ttttgcagca atatttggac ggtaatccag
    17341 ttcagccatt gctgagaaaa ctaactcttt caattcgtca gtcacctgtt ccggatgatt
    17401 gatgactcga gagaccgtca tttttgaaac attggcacgt tttgcaacat ctgctaaagt
    17461 gggcatgctc tcttcctttc taacatgttg tcattcttac tatcaattat accaaatttt
    17521 cctaacagag tttattatag cccaaaataa aaaacggaaa atcctctatc gtcatgagtg
    17581 attttccgtt tcaattattt atactttttt atcaaatttt ttgctaaaaa agtggaagct
    17641 tcttccatta gtggtatttg taccatatgt cgctgtgttt ttgaggaacg aaaaacaatt
    17701 tcttttccgt aagacttatg ccgatttttt tctacaaatc gttccgtttg tatataaggg
    17761 attttttcgt cagcttgtcc atgccaaaag aacagaggac gtccagctaa cttttccggc
    17821 tgcaatgaca aatcatagct cttaacccat gaaatcaaat caaaatagtc ttttggtacg
    17881 acataattat attccgatgc gcgccttacg atttcttttc catattccaa aggtgcaggg
    17941 gaacccatca aacacacgcc cgctactata tgaggatgtt tagccaacaa ggcgcatgtt
    18001 gtcattcccc ccatcgaaac cccgccaact gcaagctgat catgtagaag acctcttttt
    18061 tctaaatgct tgataagtgt gtcaaattca aacagatttc cgtagatact atcccaaaat
    18121 gtataggatg gaatagaaga aaccggctgt ttgcgctccc catgattcat cgcatctggc
    18181 aggatcacac gaatgccctg ctgcgcaatt tttcttcctt gcgtcaaaac taactcctta
    18241 cttgtctgcc atccgtgata atagatgaca acgggaatac gttcctctct taattctttc
    18301 agaacaactt ctaacactgg aatatgatgg acagaacgtt tcaatataat tggattcaat
    18361 tgttactcac ctattttcat taaatttcct gatcgccata gcaaccatgc tccaacagtt
    18421 gtctggaaca ggttcagtgt accaaataat ataaatgcag gactgaatgg ctcgggaaat
    18481 aagcacagag aacaaagtcc caccactcct aatgctagcg aaaggagtgg ataaatagaa
    18541 aaattcaaaa aactggcaac gctaccgaaa atattaccaa taaacagtat caaaaagaaa
    18601 aaaacgctta aaattaaacc atctgtcagc gacatctgaa aaacaatgtt ctctacctca
    18661 attggctgtt gaatcgaata gacacctaag tatatactga gaaggagact tagcacgtgg
    18721 ctggcacaaa acacacgatt gaccgttttc attttaatca cctaacctat ctttataatt
    18781 ctattataat cattttatca tttttttgta tgtataaagt ttcaattttt cttcacttac
    18841 gatttttttt gatattgttg ttatataaat gaaaggagtt ttacaaatga ttgatccaaa
    18901 aatgttgggg atgatcttcc tcattaattt tgcttatatc actctgaaca cgttacgttt
    18961 catgttgaca atgaaaggct atcgactgat tgctccactt gtcagtatgg tcgagatcac
    19021 gatttatatc gtcggcttat cccttgtttt agatcgttta gataatccac tgaatttatt
    19081 tgtctatgcg ttaggttacg cagtaggtat cagtgtcgga attttgattg aagacaaatt
    19141 ggcattagga tacatcatgg tcacaacgat tttgccagca aatagcgcag aagataaaag
    19201 tttgccgggt atactgagag aacacggtta tggtgtgaca cagacttctg caatggggct
    19261 ggaaggtgag cggctagttc tcgaaatact ttctcctaga aaaagcgaac gtgaactgta
    19321 tcgcctgatc aaagaaatcg aagagcgtgc ttttatcatt tcttatgagc caaaatatat
    19381 ttcaggtggt ttctggacta aaaaagtgag aaaacgacaa ggaaaataac tcacaaactt
    19441 aaaaactgtc taatatctaa attaaatttt aaatgttaga cagtttttat ttattatttt
    19501 gattaaaaaa catcgacata tactcatcaa tttgttatta tactttatat acttatcaat
    19561 ttaatttgga gatattatgg aaattcaacg tagaaccact aattttttac atttaggctc
    19621 tttttttgca actttgacga tcttattttt tctatgttat tcatacctta agacctcaca
    19681 tgcgccttct agtgcattag gctggttgct tttggatcat tctgatatca cagaagccga
    19741 agaaaatccg ttttttttga ttttgtcttc tctttgcggc ttactgtttt ctgtttattt
    19801 cggtgcctat ttttttcatc gacatcctgg tacgttaaac gaagcttcaa gcgtattgat
    19861 tgcatttaaa acgttttctt ttttagcaat tcttttttat tcgtttaatc acaatacgct
    19921 tttcttcttt atcatgaatg gtttagtcgt gattttatcc atttttactt attttatttt
    19981 ttcactcatt tttagccaat tgaaatgtcc gctcttcttt cgattagttc ctgtcacctg
    20041 ttttatttac agcttgtttt ccttttttgt ccttgcttta atgccactga ccaacccttc
    20101 gacgatccaa gtcgcaggaa atctgttgga tatgctcttc atcgtcagtc taggtgtatt
    20161 tatgtggcaa agaaaaaaca aacaaaataa aaagcatttt gaagcctgac tattacgact
    20221 tcataaatgc ttttttagtt ttaaacactt caatctaaaa gaataaccca agattggata
    20281 aattattaat gactcgccat tcgtttctta gtgattctgg attatcaaat ggacttccta
    20341 atctaatcag ctagttcttc ccataaaatg ccatacttga ctgaatcata atattgatta
    20401 tttaaaaatc taacttttct tatcactact tcctttgtca ttccacattt ctcaccattt
    20461 ttttgcattc ctttgtttcc agaccatgta gtgaatctaa taggtggtag ataggcaaaa
    20521 tactcaaata attcttttaa ccataaagga agagaaaggc tcctcctgca agagtcagta
    20581 taatttttgc ttactgctct cttaggtttt actcactaaa actgttccat attctttgat
    20641 ataagaaaat gcatgcggta taaatttctt gctcagctca gaaaagattt gtcgtttaag
    20701 aaaggccatt tcctccattg tcaatgaagg atccaatgtt ggtaattcaa tctcaaaatt
    20761 gtttttttcg acaataggta attctaatgt gaatgattct tcttccttta tagtattcgt
    20821 cacaagtaga gactgatgga aaatactagg ccggcgattt ttatatttat tcttacgtat
    20881 cctgtcaacg ataacttcta tttgatcaaa aaagtacgat tcatttacgt ctccaataag
    20941 ttcggctaat tctttgaatg ccttcgttac aggaagctga ttcttctgta caaaaaagta
    21001 attagccaaa gtaagcggga agtgttctat agaggaaagt gtgataaaac ggtacttctc
    21061 atttcctgca gttgtcctca gcaattctgt ctctcggctg tttcttactc cataaaaata
    21121 cgcttctttc cgttcatctt cgaaacaata cgcccaaata acttctccca tcgctaattt
    21181 ttgttcatca acagagagtc tcttcaattg ttcagctatg gtttcagcag ccgaagtggc
    21241 ttgttgcaag taatctttag gatcaaatat tggaaagttc aaatgatatc ttcgttcttc
    21301 cctcttgatt aatcctgcat cgatcaataa atcaagaaaa tgggaaaatt tattttgcga
    21361 aaattctttt ttcaattctc ttagaatcgt ttcttgttct cgatgttcat atagataatc
    21421 ggtcaatgaa gaaaaaagcg gatcatcggt cagtttttga taaaagtttt ccttattttt
    21481 tgaataatag ttcatatatg ttctcttttc tatccgtttt attttactta aaaggctttt
    21541 acgtaaaaag gaggaagaac aagagtcata attgactgtt attctcctcc atttcttcgg
    21601 cctttagtat gttctatgtt tctttttata tcaatcgctt atccattcat tttgaatgct
    21661 tcatactacc atttgattag ctaaatacag ccgtcaattg aggtacgact tgttttttac
    21721 gtgaaacgac acctttaagc aaagcacggt tgttggtcaa agttgtttgg aaagcttctt
    21781 ctactttttc ttttccttta ccagcaacaa gtaattctga atcactgtct aagatgtttg
    21841 tgacaactaa tacgaacaga tcgtagccat ttgctttcat ttcatcttcc attgctgctt
    21901 ctagctctgc ttgtcgatcc atcacttcat taaggtccac tgtattgact tgagcgatac
    21961 gaacgttgga actgcccatt gggaaacttt ttgcatccaa atcaagaaga accgcagctg
    22021 atttatcact tagatttgtt cctgctttca acatttcaag tccataagtg tttagatcga
    22081 cttcagcgat tgctgcaagt tcttttgcag ctgcttcatc ttcaggcgta catgttggtg
    22141 atttgaacaa caatgtatct gaaatgatag ctgagagcat gattcctgcg atttctttag
    22201 gaattgttac ttggttttct ttatatagtt ttaaaataat cgtacttgta catccaactg
    22261 gttctgcacg atagtacaat ggattagctg tttcaaagtt tgcaatacga tggtggtcta
    22321 ctacagctaa aatatttact tcgctgatat ctgaaatact ttgttggaat tcattatgat
    22381 ccacaagcat gacatctgca ttttctgctt tagctgactc tactactcgt ggtgcagata
    22441 gctgaaagtg gtctaatgcg tattgtgttt cttcattagg tgtacctaga gcaactgctt
    22501 ctgtttcttt acctaattca ttttgcaagt gtgaaaacgc aatggctgcc ccgattgcat
    22561 ctgtatctgg attttggtga ccaaaaacta aaatttttga catgtcattc gctcctttgt
    22621 gatttctcct atttaataat agcaaaaaaa cggaaagaag caatacttat cttctttccg
    22681 atgcgaccta tcgcgttaaa tattttgtat actcttctgt atgaagcaat cgtttagcat
    22741 tttcgacacg ttcttttgta ggtggttcga tcccttctaa tggatatttc aaaccaagtg
    22801 tttcccactt gtattttccc atcgtatgat aaggaagaat ctctactctg tctacatttg
    22861 acaaggtttg aataaagttg tctagtcgga tcaaatattc atcataatca cttcgctcag
    22921 gaactagtac atggcgaatc caaaccggtt tgttgatttt tgacaaatat tgagccattt
    22981 ctaaaatatt ttcattgtcc caatgcgtta gttttttatg ctcttcatta tcgatgtgtt
    23041 tgatgtcaaa taacagtaaa tctgtatact tcatcaattc ttgaaaacgt gaaaagaaag
    23101 gttcttcata cgtaaaaggt tttccgcatg tatccaatgt agtatgcatc ttccgctctt
    23161 ttgctttttt aaatagttcg atcaaaaaat cgatctgcaa tagaggttct ccaccactaa
    23221 cagtaatacc acctttatct ccccagtaag gtctgaagcg ttctgcttta tctaaaagtt
    23281 catctgctgt gtattctttc cctccgccaa tattccaagt atctggattg tgacaaaatt
    23341 ggcaacgcat gcggcatcct tgcataaaca cgacaaagcg cagtccaggt ccgtctactg
    23401 aaccgaaagt ttcgatagaa tgaacatagc cgattgtttt ttcttccatt taagttcaca
    23461 tcttttcttt gatttcattt taagtacaag ttagctgtcg aagcgaagct ttctgaacaa
    23521 aatttttcgc aattgccgct tcgttatgtg taaaatttac agggacggaa catacaagtc
    23581 ctgcccctgt aaatcgtttc tttcaaataa gcatactgat tattcgattt tgatgcgatg
    23641 gctattcaac gtcctttcga cgctaagtcg aaaaactttt ttcacgaact ttttacattc
    23701 tgtcgtgtga agttctcatc aagacatcta attgttgttc tcttgtcaag tcacggaatt
    23761 taactgcata accagatacc cggatcgtca agttcggata tttcattgga ttttccattg
    23821 catcacgcaa taaatcatta ctgaatacat tgacattcaa atgataagct ccttttgaga
    23881 agtatccatc taagacatta cgcaagtttt cgattcttgt atcttgttct tttccaagac
    23941 ctgaaggatt gattgtttgg gtatttgaaa ttccatccaa tgcacagccg taattcattt
    24001 tagctgttga gttcaggcta gctaataacc cactttgttc cgcattgtaa cttggatttg
    24061 ctcctggcgc aagtggtttt ccagcttcac ggccatcagg agtatttcct gtatttttac
    24121 cgtaaacaac atttgaagta atcgtcaata atgaagttgt tggttttgag ttgcggtaag
    24181 ttttatgacg tttgatttgt cccatgaagt attccaagat ccatgaaact aattcatctg
    24241 cacggtcatc atcatttccg tatttaggga agtcgccatc cacttcaaaa tcaactgcta
    24301 ttcctttttc attacggatt gcttttactt ttgcatattt gatcgctgac aagctgtctg
    24361 ccgcatgaga gatcccagca atacctgtag caaatgtgcg ttgcaagtca gaatccatca
    24421 aagccagctg agctgcttca taagaatatt tatcatgcat ataatgaatg atgttcaacg
    24481 tattgacata tagttctgct aaccaatcca tcatattcat gaagttatgt ttcacttctt
    24541 caaagtctag tatttctgat gtgattggac gatattctgg tccaacttgg gcgccagtca
    24601 cttcatcgac tccgccattg atggcatata atagtgtttt agccaagtta gcacgagcgc
    24661 caaagaattg catgtctttt ccgacaactg ttcctgatac acagcaagca atcgcacaat
    24721 catcagaacc ccattgttca cgaagctgat tatcattttc gaattgaatc gaagaacttt
    24781 cgatagcgat tctgctagca tatgttctga atccttctgg aaggtgttca gaatacaaaa
    24841 cagtcaagtt tggttctggt gaaggtccca tatttgttaa tgtatgaagc agacggaaat
    24901 cattctttgt aactaatgaa cgaccatcta atcccatacc tgcaatggat aaagtagccc
    24961 agatagggaa tcctgagaat aattggttat attcaggtgt acgcgcgaat ttgaccatac
    25021 gtaatttcat tactaagtgg tcgatcaatt cttgtgcttc tttttctgtg attactccat
    25081 tatccaaatc acgttggata tagatatcaa ggaatgctga gatacgtccg attgacatcg
    25141 cagcaccatt ttgtgatttg attgctgcta aatatccgaa gtatagccat tggacagctt
    25201 cttttgcatt tgcagctggt ttagaaatat catagccata tttcgcagcc atttctttca
    25261 tttgcgctaa tgcacgatat tgttcagtga tttcttcacg taaacgaatc acttcttcac
    25321 tcattgtatg ataaccagtc atatcatgat cttttttctt ttgttccatc aaatagtcga
    25381 ttccatacaa tgccacacga cgatagtcac cgatgatacg tccgcgaccg taagcgtctg
    25441 gaagccctgt aatgattttg tttttacgag cagcacgcat ttcagcagta taagcgtcaa
    25501 atacaccttg attatgtgtt ttgcgccagt cagtgaaaat atgtgtcaat tcatcgtttg
    25561 gtgtatagcc attgcttttt agcgcattgt tagccatatt gattccgccg aacggcatga
    25621 atgcttgttt caaaggtttg tctgtctgta gaccgacgat tttttccaaa tctttatcca
    25681 aatagcctgc atcgtgtgaa gtaatagttg atacgatttc tgtgtccata tcatagacac
    25741 cgttacgctc gaattggata tcatttaact tttgcaattc atcccataat ttttctgttg
    25801 cttctgttgg gccttccaaa aagctgtcat caccgcgata ttcagtgtag ttattttgaa
    25861 taaagtctct agtgtctacg ccttctttcc atttggtacc tttaaatcca ttccattgct
    25921 ccattgtatg gacctcctaa atttctgttt tatgtaacag tttttacgtg attagtataa
    25981 cacagcaccc tatctttgca agggttttct tgttttttat ttaacaattt ttatgtttta
    26041 tttacatata tttaaatcaa cgttgacata ccaacattta agcattgtga acactttcat
    26101 ctttttttgc aaacgtataa ggatttatta aaaatgaatg aaaaagagac gccacctgta
    26161 ttaatacaga tggcgtctct tcattaaaat actacaacag ttacgactcg atgaaaatct
    26221 caggagcatc gataacttcg atgacttctc cacctttttt ctcatccatc gcaaatgatc
    26281 cattcgatgt tcgatcacct atagggaaat cagttgggtc aatcgttaac tgctgccctt
    26341 tttgattcat caaggttatt tcttttgatc ttccttccga catatagata atacggtgcg
    26401 gatttttttt cagctcacgc atgaccgtca ctccccgctt cgcacgtgaa gtttggctga
    26461 tttcttgagc aagcatgcgt ttaacagctc ctcgctgagt aacgattacg atcggcgtat
    26521 caccttctgc taacacaagc agcccgttga taatcctatc tccatctttc aaattcatag
    26581 acttcactcc agctgccttt gctccaacaa cgggaacatc tgttaaagga tagcgcaaac
    26641 ccattccttg atgcgttact aagaaaacat ctaagcctgg ctgatcttct ttcagataca
    26701 cagcaatcag ttcatcttct tccgccttta gcttcataca gctgagcgga cggctcttat
    26761 aggtgcgcca tggttcgaac tctgtcattc gtgtttgctt gatcaatcca ttcttgctga
    26821 tgaatacaaa tgttttctct gcttgaattt tttgatatgg gaaaacagct aaaatcgatt
    26881 cgtctacaga cagattggag attgtttgag aaatgtgctc accagcatct ttccatttca
    26941 aatcgggtag ttcatggaca gggcggtaga tcacatttgc tttatttgtg atcagaagaa
    27001 catggtccaa tgtactcaat tcacctgagt atagcaagta gtcgccttct cgcatcccga
    27061 tttcttctgg tttggaagca ctataagaac gaaggcttgt tcgcttcaca tagccttctc
    27121 gcgtcacact gacaattacg tcttcttgtg ccactaagac ttgcgtatca attttgattt
    27181 cttcgatttc gtcttcgatt gtcgttagac gagcggaaga ataatttttt ttcacttctc
    27241 gcaattcttt tttcataaca gagaaaagct ctttgtcatt tgaaaggatt ttattcaact
    27301 ctgtgatttg cgcaatcaag ctttcggatt ccttttgaag ctctgtgata tccgtgttcg
    27361 tcaaacggta taattgcaat gtgacaattg cttctgcttg ttcttctgta aattgaaaga
    27421 cgtcgactaa attctttttg gcgtcttttt tgtctttact ttcacgaatc gttgcgatta
    27481 cttcatccag aatcgataaa gctttcatca atccttctac gatatgctgt cttttttgag
    27541 ctttggctaa atcgaattga ctacgttttg ttatgacttg ctttcgatgc tcgatataac
    27601 ttcttaaaat gtctttcagt ccaacttgat gcggagtcat atggtcgata gcgaccatat
    27661 tgaaattgta attgatctgt agctcagtgt ttttgaacaa ataattcaaa attccttgag
    27721 cattggcgtc ttttttcaat tcgacgacaa tttgcagacc tgttctatca ctttcatctc
    27781 gtacttcagc tattccatcg attttcttat tcaaacggat ctcatccatt tttttcacca
    27841 aggtcgcttt atttacttca tatgggattt ctgtgatcac gatttgctgt ttattaccct
    27901 tcattgcctc tatctttgtt ttcgaacgaa gaataacttt tcctcgtcct gtttcataag
    27961 cttttttgat ttcatctttt ccttgcaaga tccctcctgt tggaaagtca ggtccaggaa
    28021 tatattccat caatttttca aggctcgctt gtggatgatc gatcatatag attgtgccat
    28081 cgatcacttc agctaagtta tgagtcggga tttctgttgc atatccagca gatatacctg
    28141 tcgatccatt gacgagaagg tttgggtatc gagctggaag gactgttggt tctttttctg
    28201 tatcatcaaa attccacacg agatcgactg tttctttctc gatatctgct agcatctctc
    28261 cacttaactt ggataatctg gcttcagtat aacgcatcgc agcaggtgga tcaccgtcca
    28321 tactcccgtt attcccgtgc atttcgatca gtacttcccg caacttccag tcttggctca
    28381 tgcggaccat cgcttcataa atactgatgt caccatgagg atgataattc cccatgatat
    28441 ttccgacaga ttttgctgat ttacggaatc ctttgtcata cgtattgcca tctttgttca
    28501 tggcaaataa tatccggcgt tgcactggct tcaatccatc acggatatca ggcagtgcac
    28561 gttcttggat aatatatttg gaataacgtc cgaagcggtc acccatcact tcttctaaag
    28621 ttaattcttg tacttcttgt cgattttcca tcaggtgacc tcctattcta cttcaaataa
    28681 ctgattgttt tcatttttat ctgctcgttc ttcatctaat aaatcattag aaactgaagg
    28741 agagatttca gtatcctctt ttttatctaa gatactgcca tcttcttcga gcgtaaattg
    28801 cacgtgattt tcgatccatt ttcttcgagg ttctactttg tcacccatca gtgtggttac
    28861 tcgacgttca gcttgcgcag catcatcgat acggacgcgg atcaacgtac gggaagtcgg
    28921 atccatcgtt gtttcccaca attgttccgc attcatctct ccaagtcctt tatatcgctg
    28981 cagcatatat cctttgccga cttttttaat cattgctgcc aattcgtcat ctgtccacgc
    29041 atattcaatg acttgcttct ttccttgtcc tttggatact ttatataaag gcggtaacgc
    29101 gatatatact ttcccagctt caatcagcgg tttcatataa cgataaaaga aagtaagcag
    29161 taatacttga atatgggcgc cgtctgtatc cgcatcggtc atgatgatta ctttgtcgta
    29221 attacagtct tcgatagaaa actcaggacc gactcctgca ccaatcgtat agatcatcgt
    29281 attgatttct tcatttttca agatatcttg cattttagct ttttcggtat tgatgacttt
    29341 tcctcgtaaa ggtagaattg cttggaactt tctgtctctt ccttgtttag cagatccgcc
    29401 agcagaatcc ccttcgacta aatacaattc atttttctta gggtttcggg attgtgcggg
    29461 tgtcaatttt cctgaaagaa gagattcgcc ttttttacgc ttcttcccat ttcggctttc
    29521 ttctctggct ttacgtgctg cttctctcgc ttctctggct ttgattgctt tacggaccaa
    29581 catctggctc atttcgctat tttcctgcaa ataaaagccc atttgttcac tgatgacgtt
    29641 atctactacg gtacgagcaa ctggcgtacc aagtttttct tttgtttgcc cttcaaattg
    29701 cagaagattt tcaggtacac ggatagaaag tacagcagct aacccttctc tgaaatcact
    29761 accttccaga ttcttgtccc gttctttcag caaaccaact tttctcgcat attcattata
    29821 agatttcgtc atcgccgctt tcataccagc ttcatgggtt cccccatctt ttgtccgaac
    29881 gttattgaca aaagataaaa cattttctga ataaccgtca ttgtattgat aagcgacctc
    29941 tacttcgata ccttcttttt ctcctgaaaa ataaacaact ggtgtcaatg tatctttttc
    30001 ttcattcaga taatcaacaa attctttgat tccttcttcg taatgaaaaa tttccttgac
    30061 tggttcttct ccacgaagat cagaaagaga gattttaacg ccttttagaa gaaaggcaga
    30121 ttctcttaac cgttcggcta aaatttcata tgaaaatttc gttgtactga atattgtatc
    30181 atctggtaaa aaatggacag tcgtcccgtt tgcttttttt gtttttccta tctttttcaa
    30241 agtaccgtca ggtttaccgc cgtttttaaa tttctgctga tactctacgc catctctaac
    30301 gatcgttaca attagccatt tcgataaggc atttaccaca ctggctccta caccgtgcag
    30361 tccaccagaa gttttgtacc ctccttgacc aaactttccg ccagcatgca gcacagtaaa
    30421 aatcacttca actgttggta ttccggaagc atgcattcct acaggcatcc cacgtccgct
    30481 atctgcaaca gttatactat tgtcttcatg gatggtcaca tcaatctcac tgccataacc
    30541 tgataatgct tcgtcaactg cattatcgac gatttcatag actaaatgat gcaagcctcg
    30601 gctgtcagtg gatccaatgt acatccctgg tctttttcta actgcctcta atccttccaa
    30661 tacttggatg gacgagtcat tgtattcgtt gtttactttt tttgccaagg caaacgctcc
    30721 ttcaataata ctttgcggca aaaccgcacc acgattatca tactagaaaa ggtcgtgaaa
    30781 aaaaagaggg tagacgagaa atcaatttta attatctcct aaccgctttt tcgacattcc
    30841 cctctatcga tcatctcttc tttgtggtca tttttatttt tggttttctt tcaacttacc
    30901 aagttcaatc ttaatacaac gatccattac gatatctgta cgtcctgctt ttcttagcat
    30961 ctcagctgct tctttgtttt caatccctaa ttgtgcccag aacactttag catcagtttt
    31021 caaaaaatca cctgctattt caggtaaaaa ttcactccgt ctaaatacat ctacgatatc
    31081 gattggatca tcgatttctg tcaaattcgc atagactttc tcgcctagaa tttcttcacc
    31141 agccaataat ggatttactg gtatgatttt atatccattg tcttgcaata cctgtgcaac
    31201 catgtaactt gttcgttctg gtttattgct caagcctacg acggcaatat tttttgcttc
    31261 ttccaaatag ttgaaaatcg tttcttgtgt tggatttttt acagacattt ctgccacccc
    31321 ttgcttttct ttttattcca tctattatac ttgtatcttt cattttttca attgttcctg
    31381 ttacctattc atgctaaaat aaaggatagt tttcaacttg aaagagggta aaaaatgaaa
    31441 ttgatcttat tacttatttt agcatatctt ttaggttcta ttccttccgg tgtctggatt
    31501 ggcaaattgt ttttcaaaaa agatatccga caacacggga gcggtaatac tggaacgacc
    31561 aatacatttc gtgtattagg caaaacagcc gggattgttg tcctgcttat ggatatttta
    31621 aaaggtacat tggctacttg tttgccgatg atcttccacc tttctgggat taaccctctt
    31681 tggtttgggg tatgcgccat tcttggccat acatttccga tttttgctgg gttcaaagga
    31741 ggaaaagctg ttgcgacaag tgcaggaatg cttttaggat ttaatcctgt attttttgtt
    31801 tattcttgta tcatctttat cgttagttta ttttgtacaa gtatggtgag tttgagcagt
    31861 atgatcagtg cagtattgat cactttatct acgatcgtcc ttccttatgt agctcctgtg
    31921 attttggcta agcccaattg gttactgacg atcattgcct ttttagtttc ttcctttatc
    31981 ttttatcggc ataaagacaa tatcaagcgt atcagaaacc atactgaaag tcgaatcccg
    32041 tttggtttga atagcagcaa gaaaaaatcc tgatactttt tcattccaaa gagataaaac
    32101 gggagtgtga caaatcgatg tcacactccc ttattactta caggatagct tttttacaca
    32161 ccttggtaaa cggtgttccc tgctaacttc tcggtcacaa cctcttactt cactgtgatg
    32221 gaatattttg tcttgaagat ttcatgggca cctagttgat tgatccctac tttttccatc
    32281 aagtttccac tactgttcac cgtgtcagcg attccgcacc acggttcgat acaaacgaaa
    32341 ggcgcttctt ttggataagg agaccagatc cctacataag gcatatcttt atagcttaaa
    32401 gttacgctat gggaagattt ttcacttcga atggcgtacg catttagacc ccttgtttca
    32461 aaaaccaagg catcttgctc aaaaagttca cgattcaaag ccagattcgt atttgtctga
    32521 cctaacgtct tttgatccat atcgatgaat gggcctttca atggtaggcg taatcttgat
    32581 ttcaatggag aaaatgccag atagaaatct tcaaatgaca atccttcttc aagaggtaca
    32641 ttgaaagcag gatgtccacc gatagaaaag aacatttctt tttcaccggt atttgccact
    32701 tgataatgaa ccgtgatgcc gtctcctcct aattcatagc tgatcactaa ttcaaaatca
    32761 aatggatact tttctaatgt ctccggcgta ctccttaaga tgaaactagc catttcttgt
    32821 ccatgttcaa tgacttcaaa atccatatcc cgagcaaatc cgtgttgccc catttgatat
    32881 gttttccctt gataaacata ctgatcatct tttaaacgtc caacaaaagg gaataaaacc
    32941 ggtgcatgtc tgccccaata cgctggatca ccttgccaga tatactctaa accatgttct
    33001 tttgatttca gactgatcaa ttccgcaccg tgttcagcga tttcggcgat cagctggtca
    33061 ttttgaataa taacagtcat tgccattcct ccaacttcga cttacttttt aaaatgggaa
    33121 ggctggaaca aacatttcta tctgccccag tccccttact tctaataact gtgttttgct
    33181 aactcgtctt taaaacggga attcaatact tttaaataag ttcccttcat gcctaacgaa
    33241 cgagattcaa tgattccagc tgattccaat tttcgtaaag cattgacgat cacagaacga
    33301 gtgatgccga tactatcggc aatattagaa gcagtcagac gaccttcatc tccatccaat
    33361 gcttcaaaga tagcttgtac agccttcaat tcgctataag ataatgtgtt gattgccatt
    33421 tggacagccg ttgcactccg tacatctgct tcgatgcttc gagacttctg ataaaggatc
    33481 tgcataccga caaccgtagc tccatattct gctaagacta gatcgtcatc tgcaaacgat
    33541 tgttccatac gagataagat aatcgtaccc aaacgttcgc cagctccaaa gatcggaacg
    33601 acagtcgtca gaccaaatgg atatttctct cttgactcta ccggaaatgc agtaatatca
    33661 ctagtaattg ggatattagc ttcagttttc atcaactgtg ccactgtatc agtataagat
    33721 tcaggaaatt gtttctcaac aaacattgtt ttgattcgtt cattgttcac atcgtgacgt
    33781 tcattataac ctagtaatac tccgtcactt cctatgatat aggtgttgct gtcaagaata
    33841 ccacctagtg tgacagccat tttatcgtaa ggcaaatctg cttgcatgtc aaaagtattc
    33901 ttttgctgca aaagtgtgtt tatcttgcgg gttttcgtta gcaagtctgt cattgtcgtc
    33961 ctccgatttt ttataaaata tagcgactta aatcttcatt tgccgcaatt gagccaagtt
    34021 tgtcatccac atatgcttct gtgatcgtta tttctcccat ttgcatatct ggtgcttcaa
    34081 ataatagatc ttctagtagt ttttccaaaa tggtatgcag tctgcgtgcg ccgatattat
    34141 ctgtgtcacg gttgacatcg aaagcgattt gagcgatccg ttcaattgct tcttttgtaa
    34201 acgtaactga cacattttct gtaccgatca acgcgacgta ttgttttact aaagcattat
    34261 ttggttcggt cagaatcttc acaaaatctt cagctgtcaa atcatctaat tctacccgta
    34321 tcgggaagcg tccttgaagt tctggaatta gatcacttgg tttagacaaa tggaaagctc
    34381 ctgaagcaat gaataggacg tgatctgttt ggatgatccc gtattttgtg tttacttgtg
    34441 aaccttcgac aattggcaat atgtctcttt ggacgccttc tctggatact tctccagatt
    34501 gctgtgattt agaagtgatc ttatcgattt catcgataaa aataattcca ctttcttccg
    34561 ctaatttgat tgcctcacta tggatatcag catccttgac taattttgct gattcttcct
    34621 tgatcaataa ctctaaagct tctttgactg ttaccgtccg ttccactttt ttcttcggtg
    34681 tcaaagcacc tagagtttca tttaggtcga tccccatttg ctccaatcca ttgttcatca
    34741 ttggtgcagg tttcttttgg tcttcaactt caatggttac ttcacgacta tccagtaaac
    34801 ccttttgtag ttgttccaag actgtacggc gattgattcg aatatcttct gtcacttctt
    34861 cttgcggttc agcggtattt tgctgactag cattaaaaag attcatcatt tgttcaaatt
    34921 gattagtgga ttgtttctgt tcttttttga taccaggtac caagattttt accaaacgtt
    34981 tttctgcatt ttttttagca cttgtgtata cacggctgta ctgctctttt tctacgattt
    35041 ggatcgcatt ttctactaaa tcccgaacca ttgattctac atctcttccg acataaccga
    35101 cttcagtaaa ttttgttgct tcgactttga caaatggtgc attgacgatt tttgccaaac
    35161 gtcgtgcgat ttctgtttta ccgacccctg taggtccgat catcagcata ttttttggtg
    35221 taatatcttg ttgcattttt tcatctaact gcaaacggcg atagcggtta cgcaaagcaa
    35281 cggcaacaga tttttttgct gcgtgctgtc ctacgatata ttcatctaat tcacttacga
    35341 tttgtcttgg tgtttgtttt aattcataca tatctactca cctcttacag ttcttctacg
    35401 ataatattat gattagtaaa gatacagata tctgcggcaa tatttaacgc attttctgca
    35461 atttctttcg cactcatgtc gttttgagca tagtttttca ttgctcgggc tgcagccaac
    35521 gcaaaattcc ctcctgatcc gatagctaag ataccatcat ctggtgtgat aacttctcct
    35581 gtacctgaaa caagaagcat ttctttatca ttcattacga tcagcatcgc ttcaagtttt
    35641 tgcatagatt gctgtgtccg ccattcttga gctaattcga cagctgcgcg ttgtagattc
    35701 ccgttatatt cgtttagttt gccttcaaat ttttcttcta aagtaaacgc atctgcaaca
    35761 cttccggcga aacctacaac aacttctcca ttgtagatac gtcgtacttt ctttgcagtg
    35821 cctttcatga caacagattc acccattgtt acttggccat ctccagccat agcaaatttc
    35881 ccgtcttttt cgacggcaca gatagtggtt gaatgaaatg gtgattcgac catgtttgtt
    35941 tcctcctaaa tttgttcttt tccttatttt tacgctcttg gatggaaaga acgatagttt
    36001 ttttgtaaac tttcttttgt tacatgggca tagatctggg tagtcgataa attggcatgt
    36061 cctagcaatt cttggactgt ccgcaaatct gccccattat ttaataaatg agtagcaaat
    36121 gtatggcgca gcatgtgagg atggatatca ctatccaaac tgcttttttt gatcatttga
    36181 ttcaagacat attcaattcc agtaggcgtg attggttttc catgatgatt cacaaaaacg
    36241 atatcatgct cttcgtgata ttttgtcatc aatacctggc ggccttccct gaaatattct
    36301 tgcagagcat cttgagcaaa agaacctaga ggagcatatc tctctttgtt ccctttacca
    36361 tggatcaaca tgacctctga atcaaaatca atgtctgata ccgacaaact gctacactca
    36421 cttaaacgga tgcctgaccc gtaaaggact tccagtaaag cgcggttcct caaatccaaa
    36481 ggactatctc ctgctacgct gtcaaaaagt gcttgcattt cattttcata aaaaaaacgt
    36541 ggcagtctca aatttttctt tttgagatga acgtaagaaa atggattttc ttttatcact
    36601 tcttctttga gaagatactg ataaaacgaa cgtaggctgg ctatcttgcg actgatagaa
    36661 tttctgctat agctaggacg atgatcagct aatgcactca aatagacacg aaccgtaaaa
    36721 tattccgcct tcagcagatc agcgtctcca gattcctcca aaaaatgttt gaaatggaga
    36781 atgtcttctt catatgcttc tttcgttttt tctgaatatc ctctttcgac aatcaaataa
    36841 cgcaaaaatt tttgttccca cgtggcttct gtcattttct caccttcctt ttgtcccaga
    36901 gaataattta gcacagcgtt tataaaaaga caaataaatt gtcagaattt aaccaatatt
    36961 tctaagtttg ttcacaattg gcgcaattcc tcacattttg tttgagaaat tcttaagaaa
    37021 aacgcaagaa aaagagcgag actatccgtc tcaccctctt catggagttt ccttactcat
    37081 ttgggattgc agttttttct aattctgttt ttattgcctc attagctttt aaagctcgtt
    37141 gtgcaattgc ttcatatctt gcttttttgt ctcgaatgcg ctctggcagt tcaggaaaca
    37201 gaccatagtt ggcattcatc ggttggaaat gttttccttc cgcatgagta atgtagtaag
    37261 ccatacttcc aatagctgtt tcttgtggaa actcgactgg ttccatttct tttgctaagc
    37321 gtgcggcgtt gattccagca agtagtccgc tcgctgcact ttcaacatag ccttctacac
    37381 cagtcatctg acctgcaaag aacagatctt cgcgtttcgt tgattggtaa gtcggtttca
    37441 gcaattctgg cgaattcata aagctgtttc ggtgcatcac accatagcga acgaattcag
    37501 cattttctaa cccaggaatc atccggaaaa cacgtttttg ctcgccccat ttcaagtgag
    37561 tctgaaagcc cacgatgttg tataaagaag ctgcagcatt gtcttgacgc agctggataa
    37621 cagcataagg acgtttgcca gttttaggat cttccaatcc aactggtttc ataggtccga
    37681 aaagcatcgt tttgaatcct cgctgtgcca ttacttcaat tggcatacat ccttcaaaat
    37741 atttttcttt ctcaaaagat ttaagttctg ccacttcggc attgattagt gcctcatgga
    37801 aagctttgaa ttcctcttct gtcatcggac agttcaagta agctgcttct cctttgtcat
    37861 agcgggactt caaatatact ttatccatat cgatcgtagc tttgtctacg attggtgcag
    37921 ctgcatcata gaaataaaaa ccatctgaac cattgaatgc tttgatgctt tctgctaatg
    37981 gatgagaagt caaaggtcct gttgctacta cggtgattcc ttccggtatt tcagtaattt
    38041 cttcgtttat cactgttact aatggatgct ctttgacttt tcgggtaatt gtttcagaaa
    38101 aagaatcgcg gtcaacagct aaggcaccac cagctggcac tgctgtttca tctgccgaag
    38161 tgattactac cgaattcaat cggcgcattt cttctttcaa taaccctact gcattagcca
    38221 aactgtttcc tcttaatgaa ttggaacata ctagttcagc aaaattactt gtgtgatgcg
    38281 cctcagtcga tttgactgga cgcatttcat ataaacggac agggactcct gcttgtgcga
    38341 tctgccaagc agcttcactt ccggcaagcc ctgctccaac aacatttacc attttcaatg
    38401 aaagaacctc ttttctatta tttttggatg tcttcttcgt aatctccatt tacacagact
    38461 acttgtttac cgcctttgac tttcttctcg accagatatc cgtcacattt tggacaattt
    38521 ctgcccactg gtttatccca agaagtgaat tcacattctg ggaaacggga acaaccatag
    38581 aatagtctgt ttttcttaga ttttcgttca atgacttgtc cttcatgaca tactgggcaa
    38641 gtcacaccga tttcttttac gattggtttc gtattccgac aatcaggaaa attactgcaa
    38701 gcataaaact tcccatattt ccctaatttt atcaccatcg gatgtccaca gacatcacaa
    38761 tcgaatcctg ctggttcatc tttgatttga attttttcga ttttttcttc cgcattcgtc
    38821 agttcttttt caaacggttt atagaaacga tcaaccactt tgacccacgc ttccgtgcct
    38881 tcttcaattt tatccaaatc tccttccatt tctgctgtga aatggatatc gacgatttga
    38941 gggaagaatt cacagattaa tgaattgaca atttctccta gttcagtcgg ctcaaatctt
    39001 ttttgtgtca attttacata gtagcgtctt tggatcgtat caagtgttgg tgcataagtg
    39061 gaaggtcgcc ctaccccgtt ttcttctagt gcacgaatca acgtagcctc actaaaacgt
    39121 gctggtggtt gagtaaaatg ttgttttggt tcaatatcaa cagattggac tacatcgcct
    39181 tcttcaagtt ctggaagaat attttctttc tcttctttgc cgtcatctct accttccaca
    39241 tacacttgca tgaatccttt gaatttgatt tttgaaccgt tcgcaatgaa gatgacacca
    39301 ttttgttcta atgtcacttt cattgtatct aaaatagctg gtgtcatctg actagccaca
    39361 aaacgtgacc agatcaatgt ataaagtttc aattgatctt tatctaaata ttgtttgagt
    39421 tcatctggtg tacgaagcac actcgttgga cgcacagctt catgggcatc ttgtgcgcct
    39481 tgagcatttt tgatctttcg gtgatcatgt ctagaaaatt cttttccata cgtatcttca
    39541 ataaatgctg cggcctctgc ttttgctgta tcggcaatcc gggtagaatc agtacgcatg
    39601 tatgtaatca agccgactgt tccttgttta cccaaagtga ttccttcata taattgctgt
    39661 gctaccatca tggtttttct tgttcgaaag tttaacttac gggcagcttc ttgttgcagg
    39721 ctacttgtag tgaaaggatt cgcagggttt cttttgcgct ctttcttttc tactttttta
    39781 acttcgaagt ctgttccatc aattctagca gtgacttctt ttacactttg tgcatctggt
    39841 aatttctttt tcttaccgtc gattccccag aaatttgctt tgaatttctt gcgagctttt
    39901 ttaaaattac cgtcgatgct ccaatattct tctggaacaa attctcggat ctctttttca
    39961 cggtcaataa taatttttaa agcgacagat tggacacgtc ctgcacttaa ccctttcttg
    40021 accttacgcc agagaatagg actgatcgaa taaccaacga ttctgtctaa ggtacgacga
    40081 gcttgctgtg catctactaa atctacatcg atcgttcttg gttccttaaa agctgctttg
    40141 actgcgtctt ttgtgatttc attgaagacc acccgatttt tttctttcag atccaaccca
    40201 agtaggtacg ctaaatgcca agcaatcgct tctccttctc tatccgggtc acttgccaag
    40261 taaacttttt gagctttttt tgctgcggct ttcaggcttt tgatgacatc gccttttccg
    40321 cgtatagaaa tataatgggg ttcataattg ttttcaaaat cgatacccat tttacttttc
    40381 ggtaaatctc ttatatggcc aacactggcc attactttat agtttcgtcc aagatatttc
    40441 tcaattgtct tggcttttgc aggtgattct acaatcacta aatatttata cgccattact
    40501 gaatggactc ctttccattg tcgtgttcct actattaaaa gaggattcat acaaatcgta
    40561 gctaatcata tccattcaga aaacgtttgt caagaaaagc aaatgaaaag tatggtgtta
    40621 ttctttaaat tctgccaaga tatcttcacc cgaaaccgtg caaactgcac cgtcttggat
    40681 caaatgatga catccggtag aatgttctgt taaaatattt cctggaacag aaaaaactgt
    40741 tcttccaaga tccaatgctt gctgtgctgt tatcagagag ccgctttttt tcttggcttc
    40801 aaagacacat gttcctttag acaaagctgc gataatccga tttctcattg gaaaacaatg
    40861 ctttttcggg ccggattgag gaggatattc actcaaaaga agatgatcat ttgcaatcac
    40921 ctcttgcaag tcacgatttt cagcaggata gacttgctct atccctgttc caatgactgc
    40981 gattgtccgt ccaccatgag agattgctgc ttggtgaccg tatgtatcta tccctttcgc
    41041 gcagccactg acgatcacat atccagcttc tatcactggt tttagtaaat aataaactgt
    41101 ttttttggct aaagcagaag tgtgtcttcc accaacaacg cttaacatgt tacaagaaag
    41161 taaagataga tcaccattat aaaacagtac aattggcgga taggtcaagt gaagcagctg
    41221 agggggatat ttgggatcaa agcaagtgat aaacgactgt ttcgattgga ttttgcccca
    41281 gttagcgtga atttcctgcc aacttttgcg aaacagctcc cggtgtttgg ttattttacc
    41341 tatcttaatg atgtcttcaa atccgatttc tttataagga tactgcatca tccagttagc
    41401 aagtgcccat tttccttgac tactgattcc ttttgtataa gcaagtttca ataaattttc
    41461 ttctatttga tacatcataa aaccgccttt cgtctctctt tctaataaga tacgtaaaag
    41521 cggctgtttt ttattgtaaa tattttttta caggtgcaaa acttttacga tggattggcg
    41581 taattccttg tcgttcaagt ccttctaagt gttcctttgt tccataacct gcattatgcg
    41641 agaaaccata tccaggataa agcacgtcat attctttcat caattggtct cgatatactt
    41701 tagcaatgat acttgcagca gcaatcgaca cagatcgtgc atcccctttg attatttttt
    41761 cctgctgaat aggcaaatcc aaggtcatcg catcgatcaa caaatagctt ggtacaatgg
    41821 acaatttttc tactgcttgg atcatcgcta atttacttgc ttcataaata ttcacatcat
    41881 cgattgtctg ctgatcaacg atcccgatcc cgattgccag ggctttttct tgaacttgtt
    41941 gataaagaag ttctcgcttt ttctctgata attgtttgga gtcattcagc cctaatatga
    42001 tctcattttt cggcaagata actgcagctg ccacgacagg tccagctaat ggtcctcttc
    42061 ctacttcatc aatgccggca atccattggt gaccttgtgc gtacccttgc ttttcaaagc
    42121 aaaacatttc ttcatatttt tccttaatta atgcttcctt tttcaatcgt cgttcaaaag
    42181 aagccagtgc ttgctgcacg cctttgcgtg gatcatttct taatgattct agtgtaggat
    42241 catctattct ctgtatgctt ttcaatcgtt ctttgatact ttggatggat tcagtcatca
    42301 cttttttgct ccatttcttc gcaacgatcc agtgtgtatc gtccaagttt tccttgacga
    42361 atatcatgca cgactaattc gctgccacga tcatagtctt ctttataccc acgttttgct
    42421 gtaatatcca tcagtaattc cggtgccaat ttttcttctt gctcgattga taaaccataa
    42481 cgatcgctga ttcttcctga ataatatcgg gcaaaaaagt ctaatccgta aatcgctaaa
    42541 tcatctaaat ggacaagctg gtctttgatc gcgcctgtca gcgctagttt tttgccgatt
    42601 tcttcatctt caaatttggg ccataaaatc cctggtgtgt ctaacaattc caactcatta
    42661 cctaaacgaa gccactgctg accttttgtt acgccaggct tatttcctgt ctgtgcaatt
    42721 ttcttgccta ctagtcgatt catcaacgta gatttcccaa catttggaat acctaagacc
    42781 attgcccgaa tagcgcgagg cttgatcccc cgagcagcat ctcttgcccg tttttctttc
    42841 aatgcttctt tagccgcagg tactagacct ttaattcctt tactttcttg tgccgtgata
    42901 gctaatgcaa gatggccttg tttacgaaaa tattcttgcc acagctttgt ctgttgtgga
    42961 tctgccagat ccgctttatt caataaaaca aggcgaggtt tttgctgaat gatctgatct
    43021 agcattggat tacgagaaga taaaggtaat cgtgcgtcta ccaattcaaa tacgatgtcc
    43081 acatatttca ttttttcaga aacttctcgt cgggcttttg ccatatgtcc cggaaaccat
    43141 tggatggtca ttgttctctc cattcctttc ataccggaat attccccggc tttacttgtt
    43201 tttttctttt tcaatataaa ttcacttttt tattataaag aaattccatc tattagttaa
    43261 gtgaaagtga accagtcctc attctatcac atcttcactt ttttgatgat gcaaattttt
    43321 attttggttt ctatatatga atctaaattt ttgacagcgt ttcctaaata agagatgata
    43381 gacgaacaaa acagaaagga gacgaaacaa atgaatagta tggtttttgt taattttcct
    43441 gttgctgatg tcaatcgttc cgttgctttt tatgaaaagc tgggttttaa aaaaaatgaa
    43501 gaattttcta ctgaagaagc tggttcaatg gtatgggatg acactttttg gataatgctt
    43561 ctctctcatg atttttataa aaaatttata aaagataaag aaatagctga taataaaaaa
    43621 acaagtggtg ctttgatttc gtttagtgtt gaaaatgcgg atgaagtaaa aaaatttgct
    43681 caaattgcaa aagaaaatgg tggtactttc cacgaagtag atatgggaat gcctgaagaa
    43741 gaaatgtttt cattagaagt ccaagatcta gacggaaata cattagaacc cgtatggatg
    43801 aagatgtaag cagataacta atctgacgtt ttttataaca aaaaaacaaa ggcggatgat
    43861 acgataagta ttctccgcct ctattttttt tattcgtaca atctcttttt tacagtttat
    43921 aaaagcagtc ttctcaccct ttttttaatt gttagatgcc agtgtatgta aatcaccaat
    43981 gtgtcatgac acattggtga ttttatggta tccttttatt attaactgac aaaggagaga
    44041 atattttgaa cactttgatt gcaaaagacg tttttagatt gcccgaaatg aatgcaagat
    44101 tgttgtcgac ctctgctctt ttattagccc ttgatgtcat cttatacaag atagcgattg
    44161 gtcctgctta ttttcaaatc acattcggat ttttaagtat ggcgcttatg ggttatctat
    44221 atggaccgat ctgggctggt ttgcttgaaa tgttgtcgaa cactttaaat ttcacgatat
    44281 ttggttcagg aacgtttcaa gctgcttttc ttatcacggc tttccttggt ggatttatta
    44341 atggcttatt tttatatcat aaaaagataa acctgccttc cgtcatcgct gcccaattat
    44401 tgattatgat cccagtcagc ctttttatca attcttggct gatgtctgtt ttgtttggtg
    44461 cagatttcaa agtaattttt ctaggtagat tcatcaggaa tatgatccaa atccctattc
    44521 aaataatggt tgtttattca tttatcaaaa ctttagaggc tagaaaagtg tttaaacgag
    44581 ctgtttgatt ttacgtacta aggtagtaaa ctgattttgg attaaacaat aaagcgtgca
    44641 gtctcaacag actgcacgct ttattgtttc tcactggatc cattttattt catcaagtgg
    44701 ataatagaca aatcttgctt tacctagaat atcagtttta ttgatcgtgc caaacgaacg
    44761 actatctttt gaaactcttc gattatctcc aagtacaaaa taattatctt ccggaagctt
    44821 ggattgtccc gttagctctt gtagtgtaaa gtccgtcgta taggatgcat ttgcatgatc
    44881 tgatttcagg tttttagtta gataaggttc cttaactact ttcccattga tcttcaattg
    44941 atcattttgg tagctgacat tttctcctgg aagaccgatt actcgtttga tataaatcgt
    45001 gccatctgct aattgaaaaa caacaatatc aaatcgtctg atctccgaaa atttttccat
    45061 cacaaccata tcaccttgct tcaacacgtt ttccattgaa ttgccttcca ctggtaccgg
    45121 gatgaataaa aatccccgca acatgaacgc aaggaataca gaaacaagta agtatttgaa
    45181 tacaagccag aagcgattaa tatagcgttg tttttttgtc aatctctatc aatccatccc
    45241 tctttttttc attctttctt tattataaga aaaatatcaa aaaaatgcga ctagatagct
    45301 gaaataaaaa taattctttc aattaggcta ttggacaaaa aacttttttg atcataaagt
    45361 acaaaactat ctcttatatg tcatgattat tttctaaata tttttcccat gcttcgtcaa
    45421 agatatccat ggacggcaaa tagtcgacat tcagttccag ataattagaa atttcttcgt
    45481 agctagagct gtgcttagga aattggatgt ctttaccggc ttctgtagcg aaaacagata
    45541 aagcatcatg tgtgccaccg cctcgcagtg tcattaaata atgaaaaaag cttcgattca
    45601 cccttcgttc ctccaatttt cttcgataaa ggcagcccgg cgtgcatggt ttcttttaaa
    45661 attttcagga tgctttttat aatactcttg atggtcttct tctgctagat aaaatggttg
    45721 ggctggttcg atttttgtaa cgattggctg ttcgaaacgt ccactttcag ctaactgttt
    45781 cttacttttt tcagcaatga tccgctgttc ttctgtcaaa taaaagatca ccgggcgata
    45841 attgtcaccg cgatcctcga attgtccgaa agcgtcagtt ggatcagttt gctgccagta
    45901 aagttctact aattgttcat atgaaatcaa tgttggatca tagataatct ccactgcttc
    45961 tgtatgtcca gtcgtttggc tttttacttg ttcataagtc ggatctggta catgccctcc
    46021 agtatatcct gacatcactg tatggatacc aggaagcgtg tcgaaaggct ggatcataca
    46081 ccagaagcag cctcctgcaa atattgctcg ttccattatg attccccctc taatactact
    46141 catccgatga ttttttattt tcttttgtct tgctttcagt actgctggtg ctagttttgt
    46201 tggtatttga gttgtttgaa gcatcagagg tatcttttgg caaatataga ctaaaccgaa
    46261 tgtcatcatt tactaagtcg attttatctg ctttaatata catcccgttt tgcattcgga
    46321 attgatccaa cctaagcatg atagtcagat catctgtatt gacttcgatc caatctggta
    46381 atttatagtt tctcttgatc atattcatca catctttgat tggcaaactc aatgttccga
    46441 tagaaagact tctagctttt agttggacat ttccgttttc catcacatac ggatcaaaat
    46501 ataaatagaa atcgatagga aaacctagta cttcgaaagt accattgagt agtgcttcat
    46561 tttccaaata aaatttatat tcaatatcac tatctttttg atactcacta aggaaaaagc
    46621 tgatgatttg attgactttt tctttatttg aattgatcgt taagacagga tctccttgtc
    46681 tttccgtaag agctggtatt tctgggagtt ctggttcccg attagcaaaa atacggctgc
    46741 ctaaaaatac ggtcgaacca agtactaccc caagaaggat aaggaaggcg aatttccagt
    46801 aatttgtttt ctttgttttg tttgaagata cgtcagatct tgttttcatg tttattgatc
    46861 atcctccttc tctaaccatt ggttttgtgt ctcgatcagc tgatctctca ctgcatttgc
    46921 catcaattga taacctaaat tatttggatg gaaatgatct tcttcataga gcacattatt
    46981 tttgatgcca tttagatttt ctgtcgtgct agttgtttga tctgttcctt cttctgtgac
    47041 acctacttcc tgattcaatc cttgataaag caaatcattg attgggataa agtagcagtt
    47101 cggcattttt tttgtcaccg tttctgttcc tttgttccaa ttgttaacaa ttgtctgcat
    47161 gtcagtgatc tcaggaaagt tcaaataaaa tggattgtag atgcctaaaa tgtaaatagg
    47221 tgcggtttta ttgagggatc gaaattcttc caatagttct gtgacatttt cctgatagtt
    47281 tttcagtggc tttttaaagg aattgaccgt taacccgaat aaattatttt ggataacttt
    47341 catcaaatca ttaccgccaa cagtcagtgt gataaaatca gctgttttga tattgtttcg
    47401 aatttcttct tttgttttta ctcgctttaa gatctggtca cttcgttcac catttacacc
    47461 atagttttct gtttcaaccg cggtcaaatt ataacggtct tttagatcat ttgcgacaag
    47521 gggaacgaat cctccttgct tggtttgatc tcctactcct tcagtcagcg aatctccgat
    47581 agctatgtag tgaagttttt cttttttatt tggatcttct ctcacagtag ttactggttt
    47641 cattagtggg ccagctttcg gtatagaagc agctaaacct gcatagatga tgatcgcaat
    47701 taataatggg aacaaaacga ggatcaaatg tcgtttcgtt aatttcattt tttcacctct
    47761 tgtattcgat tggttctaat gttatcaaaa attttatcaa aaaggtagtc tttatgaaaa
    47821 aagaaaacaa ttattttcct aattttataa agaaaaagag aataagctgc aagcctttca
    47881 ggctgagggc ttatcctctt ttcgactaat ctacataata catgattgca aacgcgtctt
    47941 taccagtatg cgtagcgata accggattcg tatgcagtac agggatatgc atgtccggga
    48001 ataattcttg caaaccctct ttgaattctt gcgccaattc ttttgcatcc gcatgtgaaa
    48061 taccgatttg tcgcacattt ggcaattctt tcagttcatt tttcaaatta ttaaaccatt
    48121 tatcgaacgt tttctttcct cgccccttag ttacagggat taattcagaa tgggcgaaat
    48181 tcatcaccac gcgtatgttc aaaacactag acagcaaacc agttgttcgg ctgattcttc
    48241 caccttttac caagttatct agtgtggata ttccgatgta taattttgta ttgtcttgta
    48301 cttttttgac ttcttcaagg attttctcta ctgttttacc ttcttttgct aattcagctg
    48361 ctcgaattac ctgaaaagat aatccttggt cagtggtatc actgtcgata accgttactt
    48421 tcgtttttgt tagattactg gcttgtcttg ctgcttctac tgttccactc aagccttttg
    48481 tcatatggat cgaaatcact tcactgccgt cttctcctag ctcatcatac atcgagatga
    48541 attctccaat tggtggttgg cttgttttgg gcagattttt tgctttcgcc atcatttcca
    48601 taaatctttc gccgtctagt tggtcatcat cgggatatac tgttccgtcg atcatgatgg
    48661 atagcggcat gacacgaatg cctaaagcat cgcgtacatt tttttccatc gtacatgaag
    48721 aatctgttac gatttttaca tttgtcatta ttttctctct ctctttcttt aacaagatgc
    48781 cttattcatg ttaaactaca tgtaagacaa tttctatttt tagtataaca gacaaataat
    48841 gatttttcat taattacacc tagtaaagga gccgttttca tggaaaaaac gaaatttaat
    48901 cgaacgtatg aaatattaaa tgaagtgttt aatgcagtca cccatggaat tgggactgga
    48961 ttgagtatcg cgggactagt ggttctttta gtaaaaggtg cccacttgca ttcctccctc
    49021 catattgtct cttatgctat ctatggatcg atgatgattc ttttattttt aacgtctact
    49081 ttgtttcatt cattgatttt tacaaaagca aaaaaggtgt tccaagtatt cgatcatagt
    49141 tcgatttttc ttttgattgc aggaagttat actccttttt gtttgctgag tatccgagga
    49201 tggctaggtt ggactttatt tgtattaatc tggttgtttg cgattcttgg cattatatat
    49261 aaagcgttga cgttgcataa acgggagaga gtatcaaaag tatctacgat catctatatt
    49321 tttatggggt ggctctgtgt cgtggctgct gttcctcttt atcactctct tggaatgact
    49381 ggtgttattt tgatggtagc aggcgggctt tcttacacga taggcgcatt cttttatagc
    49441 ttgaattcta tccgctatat gcatgttgtt tggcatttgt ttgttatgtt aggtgcaggt
    49501 tttatgtact tctctgtttt attctttact taataaaaaa aataaagcta tggatgggac
    49561 agctctaaat aacagctagt ctatccatag cttttttata tcgtcaattc gcctgtcccg
    49621 ctttttacag gattctcatt acgctgatac gtttcaaatt gatgcggata acgatttttt
    49681 tcatccattt ctccttgact agtattgatc agtgaccaat cagaccagtc aacaggtgga
    49741 aaataagcat ctccatcgaa tacatgatgg atgactgtac ggtataatat cgtacaaaat
    49801 ggcagaaatt cttgataaac agctgaccct ccagcgatga aaaagatacc gtctgtttct
    49861 ttttccagag caagcacgtc ttccacacta tgcatgacat gcacgccttc tgctttatag
    49921 gaagaatctc tcgtcaaaac aatcgtctga cgattcggca acggacggct acccatccct
    49981 tcgaatgttt ttcgtcccat cactagtgta tttgcttctg tcatttgttt gaagaatttc
    50041 agatcatttg gcaaacgcca aggaagacgg tcttcttttc caatcaatcc gttttcatcc
    50101 tgtgcccaaa ttgcagctaa cattttctca tcctttctga ttctaaacag cgataggagc
    50161 tttgatcgcc ggatgtgggt catatccttc taattggata tcttccatct caaaatcaaa
    50221 tactgactgc ttttcctgat tcaaaactaa agtcggaaat gcgcgtattt ctcggctcaa
    50281 ttgttctttc atttgttcga tatgattgat ataaagatga gcatctccta atgtgtgaac
    50341 aaattcgcca accgctaaac ctgtttcatg tgcaattagg tgagtcagca acgcataact
    50401 tgcaatgttg aacggaacgc ctagaaacac atccccactg cgttgataca attggcagct
    50461 tagccgtccc tcttgaacat aaaattgaaa catcgtatga caaggaggca aagccatgct
    50521 aggaacatct tccggattcc atgcagaaac gatcaatctt ctagaatcag gagtcttttt
    50581 gattgcttcg atcacttgtt tgatttgatc gataaagcca ccgtcttttg tttcccagtg
    50641 acgccattga tagccgtaga tgtgtccaag atcgccgtat gtttcagcaa aggaatcatc
    50701 ggttaggatc ttctcgcaaa aaagcttgct ctgcttttta tattcttcat tgaattcagg
    50761 atctgtcaaa catctatggc caaaatcagt catatctggt ccattatagt ctggactttt
    50821 gatgtagcgt tcaaatgccc attcatccca aatatggttt ttattttgta atagatagcg
    50881 gatattcgta tctcctttta aaaaccaaag caattcgctt ttgatcaatc caaaaggtac
    50941 tcgtttcgtt gttaacaaag gaaacccttt ttgcagatca aaccgcattt ggtatccgaa
    51001 taagcttaat gtgcctgtgc ctgttctgtc ttctttacga tgcccttctt ccaacaattt
    51061 tcttcctaag tcaagatacg cttgttccat cctttttcct cctaatcttc tacccattca
    51121 ctcaagtatt cccaccgtgc cattttttct tcaagttgtg cttctgtttc agatacgtcg
    51181 ttttgcaatt cttgtaatcg agtgaaatta tctccttgat gattcatctc ttcttggagc
    51241 aatgagattt tttcttcaag ttctgcaatc tcatcttcaa tcgtttccca ttctttttgt
    51301 tccatgtaag ataatttctt cttttcagca ggttccttgc tctgtatttt tggtttcgct
    51361 ttttcagcag gctgctgggt ctctttttgc ttcagtaaat aactggacat gtttccgtaa
    51421 taaagttctt gttttccgtt tccttggaat actaataact tatctgctac cttgtccaag
    51481 aaataacggt catgggaaac agtgatcaca gcacctggaa aacttctaaa ataatcttcc
    51541 aaaatcgtca atgttgctat gtccaaatca ttggtcggtt catccaataa taaaacatta
    51601 ggttgctgaa tcagcagttt caacaaaaat aaccggcgtt tttctccgcc tgaaagtttg
    51661 cctatcagtg tcccatgcat aaatcttgga aataaaaatc gttcaagtaa ttctgctact
    51721 ccgatttgac tgccatctgc tgtttttgct tcttcagcag cttcttgtaa gtaagcaatc
    51781 atccgtttat ctggtgccat ttcttcattt tcttgtgtat aatacgcaag atgaaccgtt
    51841 tcaccgatag acattgtacc gctatccagg ggaattctgc cagctagaat attaagcaat
    51901 gtcgattttc ccgcaccatt tttaccagta atacctagtc tttcccgaga ttgaatcaat
    51961 aaatctaaat gttctagcag tgtttggtca tttatacggt aactgccatc tttgatttcc
    52021 agtacttttt tccctaaacg ttgtgtcgct aggttcagct ctaaatcatc ttcttggttt
    52081 acttggtaca agttctcctt tagatcttcg aaacggttga tccgtgcttg ctgcttggtg
    52141 ccacgtgcct gtacgccagc cctcatccaa gctaattcct gtttataaag ccgcttgcgc
    52201 ttttcttctt gttctacttc tacacgatca cgttctgctt tttctaagac gtaagcttca
    52261 taatttcctt tatactcgta taattttcca aatgaaagtt cgaagattcg gtttgctact
    52321 ctatctagaa aataacgatc gtgggtaacc atcaatagtg cgccacggta ttgtttcaaa
    52381 tagttttcca accactcgat cgcttcataa tctaaatggt ttgttggttc gtctagtaat
    52441 agtaaatcgg gttcatcaat caacacttgc gccagactaa ctcgtttttt ctgaccacct
    52501 gataaagtac tgattttttt atctaattca ctgattccta atttttgcaa aataatcttt
    52561 gcgttggtat ctgtagtcca agcatcttct ttattcattt gttcttctgc tttagcataa
    52621 cgtttttgca catcagggtc ttctccgttt tcccctagtt cgatcaatgc ttcctcatat
    52681 gctcgaacag tttggatcaa ggggctgttt ccttgaaaga ctgcttggag aacagttaat
    52741 tcatcggaaa attcagctgc ttgagaaaga taaccaatac ggtaatcagt tggataaaac
    52801 actgtttgcc gatcaccgtc gctgctatcg ataccggcaa taatatttaa gagacttgtt
    52861 ttacccgtcc cgttcgtccc aatcaacccg atacggtctt tttcgtggac caaaaaagaa
    52921 atctggtcaa acaaatcttt ttcaccataa gtttttttga ggtcagttac ttttaattct
    52981 ttcaacatgt tccctcctta tcttggatat tgtatcataa aaatagtgaa cttcaggaaa
    53041 atttttttgg tatttgttct ttttgtgttc tcaaaaaaag aacaggaccg attcgatcct
    53101 gttctgatat gttttgtttt ttataaaact tgaaaatttt taccttttta ttttattgga
    53161 ctcgtttttt ttgactttgc tcgaaacgca aatcggaaag aaaagttatc agatggtttg
    53221 ttcatcgtat aagattctaa caaattgata ttcctgcgat agctgttcgc agaaaacgtc
    53281 gtgatttttt cagcaacttc gtattcatca atgatttttc tttcaagata ataacctctt
    53341 agcatttttt tcgtaaacag actatcttgc tggatcatcc acgaagaaat caaattcccc
    53401 gagttcattt ttattccttc aagtttgcgt tgctggataa aaaattgaac catcgtttca
    53461 tcataaatat cagtcaagtt atctaaactt tcaataatca actgagtatt tttttgatat
    53521 gtctctctga tttcttggat atcttcatca ctaataaatg tctgacgatc agcatatctt
    53581 ctttgccaaa acattttcgg atggagaacg attcgcatta acctacggac aacaatgaac
    53641 caaaagccga taaaagacaa aatctggctt gtgatagaat gttcgaatcg agaaagaaaa
    53701 cgggagtaaa aacgataacc attagaagaa agcttgcccg aacgataact ttcatccaat
    53761 ccatcccgtt cgatcgacaa aatcagtgct tgtatttctt gtacttcttg cttttcatca
    53821 tcggttaaat cttccaagta cagatcacgt atccgttctt gataattttc tatcactgct
    53881 tcagtggcta aaaattcttt tgtattacga tcaatttcct ttatttcttt tcgcaaaact
    53941 tcaacgacct cttctaaaat catcaaagca ttcaaatccg tgcttttcgc ttcctctgtt
    54001 tccgtcagca taggcaagac aatgatccct atgaccaaag tcactaagat gacacccgcc
    54061 gtcagaaaca aaagcaaaga ccgctggtaa aacatcatat tattgattga aaatggcaaa
    54121 ataaaaatcg tagccaaact gactgttccc tttacaccgc caaatgttaa gatcaagatc
    54181 tcgttcaact gttttttgaa ctttttactg ccatctttga atacataaaa aagactgata
    54241 gaaatgaatc tgatcacaaa aagcatgaca gagattaata cgataatcgc taataaaaga
    54301 ccgtttggat ataaaccgtc tccccatact ggcgagaaca cttgcgtcaa ttcgattcct
    54361 aaaaatataa atactaatgc attcagtgta aaagcaatag ttgtccatgt actgtgggac
    54421 aagctcgaca attctgcatc aaacacagag attttcctaa aaccagaagc ttggagaata
    54481 cctgctgcca ctgcagcaat gattccagat acatcaaatg cctctgccaa tacataggct
    54541 agaaaaggaa gcaaaagttc gatcagcaga taccctgtga catcttgtgc tgatgctttt
    54601 tcgatcaaat gaattatttt ttgtttgaac cagacaagca aaaagccgat caaagctccc
    54661 ccaatactag aaactactag actcatcccc gcgtttactg ctgaaaaaga tccggtgatc
    54721 agcgcaccaa gagcaaactg gaaggcagta acaccagatg catcattcaa aagaccttct
    54781 ccttccaaaa tatgcatcgc ctttttaggg atattcactc gtccagaaag agaactgact
    54841 gctaccgcat ctgtcggacc taacgctgct ccaaaagcaa agcaggcagc aagtgggaca
    54901 cttggcaaca ggaatgataa cgtcgcacct accccgacaa gggtcaaaat gactcctcca
    54961 aatgccaaga acaaaattgt cccgaaattt ttgagaatcg aagaaatatc tgctttttct
    55021 ccttctctaa ataacaatgg tgcaataatc ataactaaga acaattcagg ttcaaaatcg
    55081 attgattgtc cccactctgt cagacctaat accactccaa ggaaaatttg gatcagtgga
    55141 gctggaatca ttggcaaaat gcggctagct atgttcgata aggtgatcgt tactgcaaat
    55201 acaataacta actcagcaaa ttccatcgtc catccccttt attttttatt ttgtgtaagc
    55261 atttttaaaa attgttcttt tttctttaaa attttggttt cgactacttc aacctgtgtt
    55321 tggttcccct ctaattcaca ctgtacacgt tttgactcca aacgaagcag atcatgtttc
    55381 agacgttcca actgacgata catcaatata tttcttttac gcaacttaca aagtatttga
    55441 cggcggtcat ccatcgaaag ggcgccatag cgatcatgca acagtttttt ttgttgttca
    55501 aaactctctc tcattttcca gatctcctat acacaaactt ccatcattat agcaaagttc
    55561 tttttggatg aaaaatattt cattgtttca tcgtttattg ctagttagaa atttccataa
    55621 atttttcaac gcctcattct attccaaata gtatcagata tcaagtaaaa cttaagaaag
    55681 ataaaagttt ctgacaaaag gatgtttact ttcccattcc tgcctttctt gttcttttat
    55741 cacaacaaaa aaatggggct gcgacaaaaa tcttgtcaca gtcccttatt ctgaataaac
    55801 ggtgtggaag agacagccta tcagtagtaa taagacacat ctctttcaca gcctcatttt
    55861 tgcgtaaaaa tcgatttatt cgaaaaattc cccgtataca tcttctacac gttgatctgg
    55921 attgatcacg atatacaagt tacctgtttt ttcgctgatt tttgttgatt gatattgatt
    55981 gtctaatcct tctgttcctt tatctagata tgggaagtac acaagatcag gtgtgccatt
    56041 tcggtaaagg atttccattc gctcgatatc ttcgtatttc aatgcgcgat taaacatgcc
    56101 catttccagt ccgcctaggt tgatatcatg tgtcgcaact gcgtcccctt catggaagat
    56161 ttcgatttta aatccagcac acggatggat ttcaacaaat tcactgccat tgattcgtcc
    56221 aaaacttgtt gtgatttgtt tgatccaaag atcgccgata tgacggcggt tgatcgtcca
    56281 ggtttctcca tttctaaaat aaaattttag cgctgtcatt tctttactca ttaaaaagac
    56341 tcctttatga tgtaatttat tcttgtacta cctcagttta gcacaaattt atgtaagtgg
    56401 tcacatctta tgttttttct tctaatgacg tatctgccca ctttaagtag ccaacaaagc
    56461 tgagcagata cagtctagtg ttttttaaat caatttttct ttcgataaaa aatccaaaac
    56521 ctgtttttta tcatttttta ttctttgttc tacgacggct ttttcagcta attgcaaagc
    56581 ttcactaacc cacttaccag gtttttttcc agtttcttct agcaagattt taccatctac
    56641 tgctaattcg cttaatgact tgataggtaa acgatcatag gattctccta cggcatccat
    56701 ctgaggtgtt tcgtcaaaat agatcatcaa ttcttctact tgcagtgcat gttttttgcc
    56761 taagaagtac aattcgaatg gttccaaagc tccagtttct cgttgtcgta gtccttggac
    56821 aagtgcttga acgtctttaa tcatttggtt agaacacttc cacgatttca aaaaggaacg
    56881 aatctcattt tcttttagat ccagttggct gatcaataat gcccatgctt ggctctcttc
    56941 tttcaatggg acggatggta attcagcaaa acgtaaaagt gcttcgcctt cttctttcaa
    57001 accgggacag caaatgtagc actctgtttc aataaatgca tggattcccg cggcccgttc
    57061 atttcccaag agcatcttga tgaattccac atttatacgt tctacagata ttttacctaa
    57121 tagctcgtgg ttttctttga tggcgtagaa ggtttcttcc tctaatttga accctagttg
    57181 actgacaaaa cgcaacccgc gcatcattcg taaggcatct tcatggaacc gctcatgagg
    57241 attgcctaca gctcgcaaga tctgttcttc tagatcttgc agaccatcga acaaatcgat
    57301 gatttctcca tcttctttca aagcaaacgc attgatcgta aaatctcttc ttttcaaatc
    57361 ttctgccaac gaacgaacga attcgacatg atctggtcta cggtagtcct gataagttga
    57421 ttccgtccga aatgtggtga tctcatattg ttcatcattt tctaatacca acacagttcc
    57481 atgttcgatc ccaatatcta tcgtttttgg aaaaagctgt ttgatttctt ctggaaatgc
    57541 gcttgttgcg atatccacat catggattgg ctggttcagc aagatatcac gaacacttcc
    57601 acctacaaaa taagcttcat atcctgcatt ctctaatttt ttcagaactg gaattgcctt
    57661 ttggtattcc agaggtaatt gttttaattt catttttcca acctttcctg cgtgtttctt
    57721 gtcctgagat aaagactcag ttgcatggtg actgtttgac aagtccgttt cagagtcttc
    57781 aaggccagga ccacttcatc ttgtttactc gtccttacgc tcaaagcgat tatggtctct
    57841 ttgattgaat ttttccatgt ttttttcaaa aacttcagtt aagtcgatat tcaatgaatt
    57901 agccatgatc atcgtaacga ataaaacatc accaagttct tctgctaccg agttaactgg
    57961 ttcagaagcc tttttgcttt tttctccata agtgtggttg acttctcttg ccaattcacc
    58021 tacttcttca gttaatcgag ccatctgagc taatggagag aaatacccca ccttgaattg
    58081 ctggatatat tcatccactt cctgctgcat actgtataaa gaacgctttt tatccatctt
    58141 tttccctcca aaactatctt accaaaactt taacgcaaat cctagataag agcaattgag
    58201 aaaatcgaat ttccatgcta catttaggaa ggaatttcta aatggaaatt ctgtgaaaat
    58261 acataattga aagctggaat tcatatggtc aaacgaaaaa cagtaaaaga agttcttttt
    58321 atcattatag gaacaagtat ttatgcattt ggtcttgttt acttgaacat cgctaatcat
    58381 ttagcagaag ggggagtctc agggatcacc ttgatcttaa gagctttatt tggtattgat
    58441 ccagcttata cgactttatt aatcaacatc ccattgattt tactaggagg aaagatcctc
    58501 ggtaaacgtt ccttggccta tactgttcta ggtacacttt ctttgtcatt ctttttatgg
    58561 atctggcaaa gggttccact agaaatcaat ttacagcatg atctactgat cgtttctcta
    58621 cttgcgggtt tagttgcagg tgtaggaagc gggatcgtct accgcatggg tggaacaaca
    58681 ggcggcagtg atattatcgc tcggatttta gaacaaaatt acggcatcac tatggggcgt
    58741 tccctattgg catttgatat catcgtctta cttgcttcat taacctatat cgacttgaaa
    58801 cgtatgatgt atacgttgat tgtttcgtat gttttcagtc gtgtgattga ttcgatctta
    58861 gatggcggat attctgcaaa aggtctactt gtcgtctcca acaaaagcga agagattgca
    58921 ccactactga tgaccggtct gcaaagaggt gtgactttcc tttctggaga aggcgcattc
    58981 tctggtaatt caaaaaaaat catctatatg gtcgttagct ctagtgaatt aactgaagct
    59041 aagaggatcg tccacgagat tgacgaaaaa gctttccttt caatcatcaa tgtgcatgaa
    59101 gtggaagggc aaggctttac ttatttgaag ccacagacaa gattactgaa aaaactataa
    59161 gaaaaaagac aaagataggc tatgaggaaa gattccacat ccagctgacc tttgtctttt
    59221 ttagtactat actattttta actaattgtt atgttcactt acccggttac ttttcttttg
    59281 tgtctgcaaa aggatctttc ggttaacttc atcagataat ttcaaaaaag catccctatc
    59341 tccatcttct agtgcttgat cgatttgagc ataaagcatt tttagttttg cctcttcttc
    59401 tttttcttga aaatatcgtt caattaattc agtatcttct tcactgactg aagaatccca
    59461 agaagaaaat ggattgtctt ctaagataga tagatattct cttgtctgcc aagcattttc
    59521 gaatatacat tccacatata aaggcttttt ccaattcaaa cggatttcat gaaaaatctg
    59581 gtctgtgtcc gtaaattctt ttccctgcaa aaacaatttc atgggttccc cttcaacaga
    59641 tagatcactg atctgcagtc ctcgatccgc aaaattcgcc ccttcaacaa agtggacatt
    59701 gcttaaaatc gcttcatgat tggcaagata attcaagatc caaaaaactt ctcttcggct
    59761 aaaagataca tgattgacca tccacgttaa aaaattcttc ttttcccgta catcaattag
    59821 catttttctc acctctctgt taggtcatct aataatgaca gtgcctccat atctcctggt
    59881 tcaagtgtta aataataagt caataattct tgcgctcttt tcagctgccc ttcttctctt
    59941 aagaaaaagg catactcttt caagaaatct ggttcatgtg atagttcatg ataagcctgt
    60001 tcatagtgta cagctgcaac ggtaaagtct tctaattcat tataagcatg ggctaggttc
    60061 cattctgcat aaggattagc agtttcttcc atctgattga tcacttgtat cacatcttca
    60121 tatctttcat catccaagta aagattactt aaagtaagta atgtttcatc ttgtttgtct
    60181 cctacttcta aagctttcag taaaagttct tctgctcgct gtctatcatg cagacggaaa
    60241 gcattttccg aggccaggtg ataaagttcg acttggtaag gattttcttt gattccttct
    60301 tctaacactg tttgtgcttc ttcaatcatt tcttcttctt gaagagcttg tcctagatat
    60361 agatataacg attgataatg cggattaact tctcgaagtt cttccagata gttgattgcc
    60421 tgctgatttt ctttcaattg aagattcgta aaagctagct ggaacagtcg atcatctgtc
    60481 ctttcttctt tcagtgcttc ttctaaaggt acgatagctg cttcgaattc tccttgcata
    60541 cttaaggatt gtcctaaacg ttcctgcatc gagattcctg aaatttcatt tatcccgctt
    60601 gccaacaatg tttcataaac cactgctgcc tctttgaaac gatcaactga aaaatacaat
    60661 tcagctagcg caaactggat caatggttca tcaggaagca acccagctgc ttctttcaat
    60721 tttgcttcac tcacttcagg gattccgata acttggtaca aatcagctat cgccaataag
    60781 ctttgcggat agtaatcact ttgcttatcc actttttcca ggtattcaaa agctaagtcg
    60841 atctcattat cttcgattgc aatttctgct aacgggatgt tcagtccgtc attttctggg
    60901 tattggttga tcagttgttc aaaaatctgt tttgcttcga tcaaaaagcc aatagccagc
    60961 aattcttcgc ctagttcagc taatatatct gctgggtctt cttttaatgc tttttctaaa
    61021 aagatttgtg cttgtgacaa gtcttcatct gataaagctt gcaacatttt ttcgctattt
    61081 gtattcattt caattccctc ttatctcact gacgatttgt tgaaataccg tcattgttct
    61141 caataattct ttttcgtttg gatgttggta tccgtctatt atacctattt tttctaaaac
    61201 aagtattttt ttgctttttt ctgccaaaaa aagaactttt tccaaatact ccatctttga
    61261 aatctgttcc agccagtgga ttggatagcc aagcaagtcc agccacacaa aaaagttttt
    61321 tagttggaaa tcaaaaggat atgcttggag attccacacg aaatgaaaca tcattcctaa
    61381 aaattttttc atactagcag aaagtagatg gccattttcg gtcagataaa aagcttgttc
    61441 aaacagttta ccataatttg acaggttttc tgcctctaat tgataaaaat agatcatttc
    61501 ttcgatcatc ccggcaaacg gccgagtcgt taattgcttt ttatttggat agtttttata
    61561 cagattttgc aaaaaacgat gatcacaaat cattccgcaa cagataaaag tcaaaaagtc
    61621 aatctgcttt ccgtccacct gccgctcgct gattgtttga tcataaacga tgcgttctgg
    61681 cagattgatg gtttgcagca ctacacgatt tggtagctgc aaaatcgtcc gctgcggtgt
    61741 taatgctcgg cttagagaac ggatcgatac agggatcatc catagtgatg aatcaagggt
    61801 tgtatgtttt tgaaaaaaac ctgccagatc catgatccct tcatttccaa atccgatgat
    61861 aaacatggat tgattttcgg gatagcgttt gacgaaatca agcaggttct ttaattctgt
    61921 taaatgattg cattgagtgt tggcacaaat ataccagtca ttgtttgctt gatttgcaaa
    61981 taacgggttg atcttatctg caaacaaatc ataatagcgc tgattcgtta aaaataagat
    62041 tggctgatca atggaaagtt ctcttagctg actgactagc gtttctccgt aaaacacttt
    62101 cgtcaacgca tcttctactt gataatcaag ttccatacgc atccctcctc ttcttatttt
    62161 tattttacca ttagtaagca aattctagaa aagataagag caaagctcac ctcataactt
    62221 gcaaataaat aaaaattaaa taaaatacat gtgttttcta tgtatgacat acggattcgg
    62281 aatctctgtc tcttatttat tccttttctg ctaggaaata aaaagaaaag cacttgtagc
    62341 cctagagcca caagcgcttt ttcaactgtc ttatttaaca gcgtctttta atgctttacc
    62401 tggtttgaat gcaggtactt tgctagctgg aatttcgatt tcttcaccag tttgtgggtt
    62461 acgacctttg cgagctgcgc gttcgcgaac ttcaaagtta ccaaaaccga ttaattgaac
    62521 tttttcgccg ttagctaaag catcttgaat agttgaaaat acagcatcta ctgctgcagt
    62581 tgcatctttt ttagttaaat cagtagctga agcaactttt tcgattaatt ctgctttgtt
    62641 tgccatggat agattcacct cctccacaag agatatgata gaaatatcat ttagttaaaa
    62701 ctttctgagt ggtccagaag tttaaaaaga aatattgatt aacttcaata ttctgttatc
    62761 acgatatcat atgaaccgct taatagcaag gtttttacca attttcacat gcttttttta
    62821 gtcatagaaa cgtaacaaac gaaactgtct ttttcttttg aaaaaaaaac gtcgatatgg
    62881 taaaatgcct attttctcct acgagggata attcggatgg acgtcccttc aaaagtaaat
    62941 gcttttctga tttgattttc taagaaacgt tcataagaaa aatgcatcaa ttcctcttca
    63001 ttgacaaaaa cgacaaatgt aggtggtttg acagcgactt gtgtagcata aaaaatcttc
    63061 aggcgttttc ctttatctgt tggtgttgga ttgattgcta cagcatccat aatgatatca
    63121 ttcaacacag ccgaagagat acgaagattc tggttcatac ttacttgttc gatcatttca
    63181 ggcagacgtt ccaaccgttg tttagtcact gcagaaacaa aaacgattgg agcgtaatca
    63241 agataccgga attcatcacg aatctcttgt tcgaaatcac gcattgtatt ggtttctttc
    63301 tttacaagat cccatttatt cacgacgata ataattccac gaccagcttc atgggcgtaa
    63361 cccgctactc gcttgtcttg ttcccgaatc ccttcttcag cattcagtac catcaaaacg
    63421 atatcagaac ggtcaatggc acgcattgca cgcatcacgc tgtatttttc agtattttcg
    63481 tatacttttc cgcgtttacg cataccagct gtatctatca ttaagaattt ctgaccactt
    63541 tcagaaacga agtgggtgtc gattgcgtct cgggtcgttc cttcaatatc cgaaacaatt
    63601 acacgttctt ctcctaaaat cgcattgatc aaagaggatt taccaacatt tgggcgacca
    63661 atcaaactaa acttaatcgt gtcgtcgtcc tcttcttcag tctcttcaga gaaatacttc
    63721 actgcttcat ctaaaatatc accaatccct agtccatggc ttcctgaaac aggataagga
    63781 tcgcctagcc ctaaggaata aaattcatag atatcgtttc tcatttctgg attatctact
    63841 ttattgactg ctaaaatcac tggtttatta cttctgtata aaattttcgc aaccatctca
    63901 tctgcgtctg tcacgccttc gcgtccgctg actacacaaa tgattacatc tgcttcttca
    63961 atcgcgattt ctgcttgatg cttgatctga tccataaaag gttcatcgcc aagatcaatt
    64021 ccgcctgtgt cgatcacgct gaattctcga cctaaccatt caccttttgc ataaatacga
    64081 tcacgagtta ctccaggagt atcttcgaca atcgagatac gctcaccagc gatgcggtta
    64141 aaaatcgtag acttaccgac gttcgggcgg ccaacgattg caattgttgg atttgccata
    64201 ttatttcctc ctcacaagtt tccaatctca cttagtttaa cgaatgcatt gccaactttc
    64261 aagcatagat tgtcaattaa acgaagtatt tttattcctt attgaaatac taatcgcttt
    64321 tcaaaagaaa aactgagaca aaagcagctg ctttcatctc agtcacagat acaaaatcaa
    64381 ttatttttca gaatcatcgg ttgctttttc ttctacttct tctttcaacg catcacctaa
    64441 aatgtctccc atagtaaatc cagtattttc ttctggtaat tcataagact caacattttt
    64501 tggttcttct tctgaagctg gtttttcttc taaagctttg atactcaatg caatacgatg
    64561 ttcttctgga tggatctcta atactttcac tttcacttcg tcaccttcat gaagcacttc
    64621 atgtggtgtc gcaatatgtt tatgtgaaat ttgagagata tggactagcc cttctactcc
    64681 agggaacact tcaacaaagg caccgaagct tgtcaaacgt ttaactgttc cgtctaatac
    64741 tgtgccaact ggagcttttg tatcgatttc tgaccaaggt ccaggctgtg tgtctttgat
    64801 tgacaaggaa acacgttctt gttcaggatt gatagacaac actttgacat ttacatcatc
    64861 attgacagcc aatacatcac ttggttttgc tacatgacta tgtgaaatct ctgagacatg
    64921 gactagaccg tcaattccgc ctaggtcgac aaatgcgcca aaatcagtaa gacgtgcaac
    64981 acgtccactg agaacatctc cctcatggat agttgaaaga atttcttttt tcttttcttc
    65041 tctttcgttt tccactaccg ctttatgcga taagatcaaa cgattttctg atggttcgat
    65101 ttcgatgatt ttaaagctca atgttttgcc tttatagtct gaaaagtctg caacaaaatg
    65161 atcttccacc attgatgcag ggacaaaacc acgtacaccg acgtcaacga ctaaaccgcc
    65221 tttgacaaca tttgtaacag gtgcttcgat gaccttgccc tcttggaaat ctctttcgat
    65281 atcttcccaa acttttttag catctaaacg gcgttttgaa agtagatagc tgccgttttc
    65341 tttatctttg ccgatcgtac tgataacgac taaatctaat acatcaccga cttttactac
    65401 ttcgctgata tcttctaccg gcaaagttga taattctttt gccggaacga ctccttcaac
    65461 tccagcccct tcgattccga caatcacttg tttgtcttca atgactaaaa cttcgccctt
    65521 aacaacatcg ccaactttta cttcttgtac gcttttcatt gcgtcttcca ttgactggtt
    65581 gttctcttga ttttgatcaa attctgtcat aacacttgtc ctcctaacca acattctgcc
    65641 gtaagtacgg tactgttttt agtttaattg attattcaaa aaaaataaag cgatttcgtt
    65701 cgttttcctt gaaaaaacaa ttgtttttca ttttttttct taatttaaaa aagaagataa
    65761 ccttttttca aaacaacagc ttttattgct gcaacgactt ctggaatcga tttgccagtc
    65821 gtatcgatac gaacagcatc ctctgcttgc ttcagcggag agacgtccct tgttgaatca
    65881 taatggtctc tttcctgtat ctctttcgtc agtgtttcaa gatcagtcgg aattcctttt
    65941 tcttggttct ctttgaaacg tctttctgca cgctcactta cgcttgctac taaaaagatt
    66001 ttcacttctg cattcggtaa tacagctgtc ccgatgtctc ttccgtccat gacaacgcca
    66061 ccgcgttccc ctatttttcg ttggacagca actaattctt ctctgacttt tccatgtgca
    66121 gagacttcag aaacagcttt tgtgacatct ggttgacgga tttctaaagt cacatctttt
    66181 gatgctatga atacatgctg tccatcttct tgttgcgaaa aagagatagg atactttttg
    66241 atcagcgaaa ctagcccttc ttcatctgaa aaagatacat tgttcgtaat agctaaataa
    66301 gttactgcgc gatacatggc accggtatct gtataaatat aattcaattc ttttgctaat
    66361 atcttggcaa cggtactttt cccagatgaa gcaggcccgt cgattgcaat actgatttgt
    66421 gtcatgatat aactcctttt tctcagaaaa aaagccgcaa agcgcggcta ttattattta
    66481 attcttaatt cttgaccagg gtaaagcata aagttgtttg gatctaagcc attcaattca
    66541 aacaattgat cagtggtgat ccctgcacgc tcagccactt gttttggacc ttcgcctgct
    66601 tgaacagtcg ttgttgaacc ggctgcagct gatgaagaag gtgttgtttc tgctgcattg
    66661 ctgcttgaat cccctgcttg ataagttgcc tcacttgagg aagtcggtgt tgtctctgct
    66721 gcaatactgc tttctgacgt tacacctgta tcttgagaca cagtagattc ttccgcgatt
    66781 gtactagatt ctactgttga agtctcagtt gactcctctt ttgttgtact tgtagaactt
    66841 tctactactg atgtcgaagt ttcagaagaa gttgctgctg ttgcattgtt gcttgatcca
    66901 tttctgatcc agaaataagc acctgctgga atagcgatac ataagaccag taaaatcaaa
    66961 aatagcgaaa gaaataatgt atttcctttc ttttgttgtc tctgagaact tcttgatgaa
    67021 acttcatcat ctgtatcgta gattggttgt tcccatggtt cttgtgtttc gttattttct
    67081 gtagattgat gtctatcttt tctgctcact gttttacctc ctaaactcta tcgtgtgtat
    67141 tataccatag gaaaaagtgt cttgtcctaa aaaatcaatg ttccatgttt tttttaaata
    67201 aatttagtaa aatcgttccc caatgaagtt gttcagtctt agaaaaaagc ttcctctttg
    67261 gcagaagttc tgcttttgct ccatcaatat cacaacaatt ctgcggcttt tcggagagtt
    67321 tttcgccaaa ataagctaag atgaattttc tgcggcagtt ttcttcatta atatagcgaa
    67381 gcatctgctg caggcggaat tctttttctt tttcctgacg tttgagccgt tccacccaat
    67441 tttctggttt ttcagactgc tggatcagct ccatccattt tttttgcagc tcatcaaagg
    67501 gagcttgctc tgtggcatat tccaaataaa gctcaaaact ttgtcgctgt tctctagaaa
    67561 gttgattaaa gaaataatgg atacgttcat ccccactttg ataaaaaaga attgctgcac
    67621 tttcttcctg atctctgcct gctcgaccga tttcttgtac atagttttct agactgtctg
    67681 gcaaatcata atggaccaca taacggatat cagatttatc gatccccata ccaaatgcat
    67741 tcgtagcaat gagaaactgc agctgatttt ttacaaactg ctgttgaagt tgtcttcttt
    67801 gagctgcatc aagaccaccg tgatagtatc caactgtaaa acgttccctg aataaatgat
    67861 acaatcgttc gacttctttt tttgttgcac aataaatgat tgccgctcct tgtgctcttt
    67921 ccatgaagtg ttcaagttct tgttcttttt gctgcgtttt ccgaacaaaa agcgagatat
    67981 tttgccgatt gactgattgt ctgatctctt ttggtggtcg atcaaatagt acatgacgta
    68041 tatctcttgc tactaaatct gttgctgtcg ccgttagtgc cagtgtgacc gggtttccta
    68101 aaagctttcg gatttttcct aactgttgat attctggacg gaaatcaact ccccattgag
    68161 acacgcaatg agcctcatct actacatata acgcaatatt ttgttttttc agatgctcta
    68221 aaagagaagg attagtcaac atttcgggac tcaaaaacaa aaatttatat tgcgatagat
    68281 gacggaggac gtatcttctt tcagattgcg aaagtaaact attgaaagca gctactcgtt
    68341 tctcccctcg tttttgtaat tgcgtcactt gatcttccat tagagaaagc agcggtgaca
    68401 cgatgatgac cagaccttcc attaaatacc ccgtcaattg atagcaaagg ctttttcccg
    68461 ttcctgtagg caaaatagcg agagtatctt ctccatcaag caacgcctga ataatttctt
    68521 cttggccggg acgaaatgaa tcaaatccaa aatatttttt taattcattt attaacattc
    68581 tgtatcgctt cctttctcaa tagatagatt tgatacaaac gaaattctcc ataatctaat
    68641 tgtccatcta cattccattc gctaaagcgc cactctcgca cggaatcctt atttggttcc
    68701 aaacgttcga ttgtttctgc agagagaatc cactcgtatg gaaaatcatc aaaaaacaag
    68761 gcccactcaa taagatgatc tgttactgtt cctcttttta aatgacggat tgccatgatc
    68821 tggtcaattg tctgaccatt cataaacatc tgcttggtga tcatcatgct ttgattgaaa
    68881 ttttgctgta ataatgaatc gatcaaagcg tgccaaagcg aatctggccg tttttcgatt
    68941 tgtgctaaca aaaggtggat acatctgctt tgttgcagat aaaccgctga ctcatcattg
    69001 ttttttgcca gctgataagg aagcagccct gttcgctcat ttccagataa ttggttagct
    69061 aaaaaatctg ctgcttcttc tggtatctcc gaaaacagct gcaccaaact ctcatacgca
    69121 gtatcaatca aaatttcacg tggcaattgg ctttcactaa gccatttttt tagttggaaa
    69181 gtataaaaag gacttgtctc tgctggaaga tagtcttgaa tacccgttgc cagattagaa
    69241 attacttgaa cagcaaattt aatgagccgc caactagttt cccctgttct gccatagcgg
    69301 tcaaaacgca aaccagtatg ttctatttga tgttcggaca acatatcagc ccctgcaggc
    69361 gttagctttg cttcattttc atttatttcg atccaacctt gctgcgcaat tttttgcaaa
    69421 atttgataaa acttatcctg cttcaattct ggaaaactgt tatggataaa caaaagttcg
    69481 tgggtaaatc cataaataag tactgaagtc gttcgttttc ccacaaggag ttggtaaaga
    69541 gaactaatcc gcagcttgtg tcctgatgaa aatagcgata aaataaaaac aatcatatta
    69601 ttctccttaa gttaggatgg ttagaaatgt cactactatg taaacttgta cctgaacgct
    69661 gtattgcatg cggtctttgt caaatcgaag cgccagatat tttcgattat gatgaagaag
    69721 gaatcgtttt atttgcccaa gaaccagagg ctcatcaaca gttcgtgatg ccggaagaag
    69781 aaacatatgt aaaaaaagcg tatcaaaaat gtccagttcg agcgatttta ttagaaaata
    69841 aaatataaat ataaacgaaa ctttaaaaac gtacactaag ttctctaaac ttgaaaataa
    69901 gccgggatct gtttctcttg ttccgtgaaa tcccgactta ttttgaaaga ttcatttgct
    69961 atctatagtt aattgactag ttttttcacg gaccctatag gacccattta tattatttca
    70021 actttttcag ccagttttcc aatgtattga cgatcacagt ttgctggtct gcgttagaaa
    70081 tttctgcctc tccatctcct ttttgctcac catagctgcc aaaacctcca tgatttccgc
    70141 cattgattga tacatactct gttctttccg gtaaatactg cttagcttct tgataagctt
    70201 cctgattcaa tactttatct tttgtcgccg tgatcgataa aacaggaaca gctgattctg
    70261 tcaatgttcc ttttttgtcg ggataacttg ccatgaagaa tacccctttt aaatgtttgt
    70321 ctgaatgatt cttattgaca taacgacttg ccattacgcc acctaatgaa tggccaccga
    70381 tcacataatc ggaatttgga aaatcttctt tgaccttatc cgctttgttt ccgcccatca
    70441 ctgctagatc aagtggcatt ttgacaatag cgactgaaaa gccgtttttt gctaaatctt
    70501 gcgcccaaat actataactt tctggctcta cgagagcacc aggataaaaa ataagtaatg
    70561 gagactttcc atgattcttt ttctctcctt caaaaaataa gtaatcttct ttgttttttc
    70621 cttcttttac caacacttgc gcttctgacg atggttcgta cgtattttgc tgtatatagt
    70681 aataaccggc tccaccgagt aatcctaaaa tgatgactaa gccaattagt attcgtctaa
    70741 atattttcac tttctcccac cttttctatc tgagtgaccc ctttttctta atcaagtatg
    70801 attatacctt aaaaaaataa gagagaaatg caaactttcc agcatcaaat aaaaaaagac
    70861 ggaatatcca tttgaatatc cgcccttttt gtatgtttat ttttatttag cacataaacg
    70921 atacacagct tctgcataaa tttccattgc tttatacata ctacttaatt cccatcgttc
    70981 attcgcctgg tgcataaagt caggagtatc agggaacatc gcaccgaatg ccacacactg
    71041 gttcatcgta cgagcaaaag tagcgccgcc tgatacaaac ggttcagtca tgtctccagt
    71101 aatatcgcga tatgtcccca atagattttt cactaactca ctgtctagtg gcacgtataa
    71161 tgaatcaagg aagtcaaatt cttcataagt caacccatat ttttctgctg ttttagttaa
    71221 tttagctact aaatcatctt tcttgaatgt aacagggatt ctcatatcta caccgatttt
    71281 tgtttgttct ggtgtgattt ccaaacttgc aaagttcatc gttagctcgc cggattgttc
    71341 atcttctgtt ttgcccacga cagcttcacc agttgcattt tcttgaacta attttcctaa
    71401 gaaattgatt gggccaaaat caaatacttc tgaaagagca attgccagac gagaaatagc
    71461 attcactcct tgtgctgcat ctttcgcgtg gatactttta ccaagaacga cgatgccttc
    71521 accttgttct tcgaaatcga attcgtgttt tttcaatgct tcttttactt cagaaagctt
    71581 ttctccagag taaggagctg catcaggaac aacattcaac gctcctccag cttttacaga
    71641 aaactcgttc gttcctggtc ctgtcaagta agcttgcaat aagccttttt ctgcataaat
    71701 taaaggaaat tcagcatctg gcgcaaatcc ttgcgtaatt ccttcttctt tttcgttata
    71761 tttttctaaa caacgccata aattttcttc atctgtacca aagataaaac gaatacgtgt
    71821 cttgaattcc acgccagcat caatcaaagc tttgacggca tacattgccg caatagaagg
    71881 acctttgtca tcttgggatc cgcgaccaac taaccagccg tcttttatag ttggatcgaa
    71941 tggttttgtt tcccaattat tttcgtcccc tgctggaaca acgtccatat gacacaagat
    72001 accgaataat tcatctccag agccaatctc tgaataaccg taatagcctt ctggatcttt
    72061 aaatgttcta aatcctagct tttcactgat ttccaatact ttatccaaag cttcaatcac
    72121 ttttttaccg aagggatgtc cttgtcctga atctgcttca tctagtacgg aaggaattcg
    72181 gatcaattcg ctcaatgatt ctaatgcttg ttcatgatgt tgttctgtca caaatttttt
    72241 catgatatta tcctcctaat atgttaaaaa gggtcatgtc aaattcctcc gacacaacct
    72301 cttcttctca aataatgacg ttttaagcct gctccatcag caagcagaat gttcttaaca
    72361 aatgatgaaa gaaaaaacac tcactgaatg gagctattga cttatccacg tgcttatcga
    72421 tagccgttta tcggtttctt cattcttatg atagaccttg tacctgtatt tgtctaggtt
    72481 tagaacattg ctgctacacc taggatcaca cagatggcta caaataatat cgcaattaat
    72541 ttaccggtaa atttccacca cactgaaaca tcgaaacgag caattgctac agcacccatt
    72601 acgatagcag atgttggtgt aattaagttt actaaaccag atgcagattg ataagcagtg
    72661 attactaaat ccttaccgac gccggcaaat tcacccatag gtcccatgat tcccattgtt
    72721 gcagcagcta agccggaagt tgaaggaatc aagaatgaca tagggatata gaaaataaat
    72781 gtaataatga tgaatacact tgaagataat gaacttaatc cttgttcgcc ccaatgtaag
    72841 atggtgtctg tgattaatcc attgttcata accacttgga taccacgagc aacagctact
    72901 acgattgcta caccgatcaa atcagaagca ccagctaaaa attcagagac aaattcagac
    72961 tctttcatgc cataagtgat tgctactacg atggacatta ctaagaataa catagtaatt
    73021 tctgggaagt accagtcacc taatggaagc atgcttttac ctagaaccgt acctagtacc
    73081 ggaaggtttg ttaaccagtt tgtcaatgat tcaaaaatcg tgaaattcgc attcaaggtt
    73141 gtccaaggaa tcaaactgat gatcatgata ccaaaagtaa taaagaacaa tacattaaca
    73201 tgtttttgtt ttttcgtgat tacttcttga cgaccgattg cttcaatatc gaaatgcttc
    73261 atatcttctt tacgttggtt gtatactaat gattttgttg gatctttttc gatctttgat
    73321 gcataacgat acacatatac aatagaaata gctaacaaaa taacgaacat caagaatcga
    73381 agaccaatac cttcacccat cgaaatccca acagcttgtg aagctacgcc tgttgcaaaa
    73441 ggatttaccg ttgaagctag acagcctact tgagacccta ctaatacgat tgctacagct
    73501 actactgtat caaagcctac agccatcatg actgggatca gtaaagcata gaatggaatc
    73561 gtttcttctg ccattccgta agtagagccg cctaatgcaa ataacagcat caatactgga
    73621 ataagcattt tttcttttcc tttgaatttc ttcacaactg aagcaatccc ggcatctagt
    73681 gcccctgttt tgttgataat acctaaaaat ccaccaacaa ccaaaatgaa gaaagagatt
    73741 gggattgcag caggtgtttc tttagttagc tcccccgctg gtacacctag catcccattg
    73801 attggcgcca tgaaaatatc ccacagccct tgaggatttt gttgtactcg ttcatatgat
    73861 ccagcgacga tgttgcctgc atcgtctaca ctatagtgcc cagctggtat aaaccaagta
    73921 agtacagcga ttactgcaat aataataaat aagaccgtat acgctgaagg catttgaaat
    73981 tttttctttt ttgtttgttc catcttcttc ttcctttctt ttccgttaga gacaacaatt
    74041 ttggctctaa tgttatttta tcaaaaagag tatcagaaca aaaataataa cacgcatttt
    74101 gtaaaacttt tgttcaaaaa gttcgttttt ccctattccc tcctcttttt tcaggttttt
    74161 aaagctttct tctttttcat tgtagcgttt cctttttttt ataaacaaac attttcgtct
    74221 tttaaaagga gaagaatttc acatttgcaa agaattgatt gatttttatg cataaatcaa
    74281 aaaaatactc aaaacaaaca aataaaacgt ttacattatt gcatgtcttg tatttttttc
    74341 caaaaaaaaa gaccaagaaa tttcttgatc tttttgatat ttatttgact gctgtatgac
    74401 gttgttcgaa ctgatgttgt tttcgactta accatggaag aagttgcgca tgcagcacta
    74461 aaaagacagc actcacgatg aatcctttga tcaagttgaa aggaacgatc ccaatcagta
    74521 catagtttgc taaagacatg cccagcatct gtgttgcgtt cagccctaaa aacattaagt
    74581 aaagaggcgt aataacgaaa taatttgcga tactcataaa aatagttaga gcgatggttc
    74641 ctgtaatgac acctaaaaat ttgtttcttc ctttatgctg tttctttaca ctaaagaaat
    74701 aataaatcgg gaatgtaaag atcgttgttg ataagaaact agcagtgtct cctaccaaat
    74761 tatccggaga aaaacctgta gtcagcagat gtaatactga acgcaagaac gctgttgcaa
    74821 ctccggccgc tggaccgaat aagaacatgc tgatcaatac cgagatatca ctaaaatcga
    74881 tcttcaaaaa actaaaagcc ggcatgatcg gaaaagcaaa atactgtaaa actaatgcga
    74941 tcgcagcaaa catcgctact gcaaccattt tctgtacacg ggtgttcttc atttgaaatc
    75001 ctcctgttag gactcctctt cagcgaactt tttgacgttt ctctccaaat gaaaaaactc
    75061 tattttccag ggaaaataga gttagagtta tttgatcaag cgtcgtcaaa taagctctat
    75121 cttctttatc cagactatac tgtcggtatc ggaatttcac cgattcagct atttttttgc
    75181 aaaataggtc gtggactata accaccggtc gggaatttca ccctgcccct gaagacgaac
    75241 cttatataat ttttgtttac atattcatta tacatatcta ttcaaaaaac gcaacatcta
    75301 acacttataa aaagtaagtg ttcattttga gtggttcagc aaactgctga cttctttttt
    75361 gttcagttca cggtaatccc caggacgtag gccttgtaaa gtcagatctc cgtatttttc
    75421 acgttttagt ttttgcacag gaagaccaac tgcttgaagc atatttttca cttgatgatt
    75481 acgtccttcg tggatcgtca attccacgat actgtggttt gtcttaggat ccactgataa
    75541 aatttggaat ttagctggag atgtttttcg tccttcgatc tttattcctt ttgtcaaagg
    75601 tgcaagcatc gattttgtag cgatcccttt tacctttgca acgtaaactt tatccacttc
    75661 atgttttgga tgtgtcaggc gctgagcaaa atctccatca tttgtcagta gcaagatccc
    75721 cgaagtatcg taatccagtc gacctacagg atagatacgt tcttttacca tcggcaaaag
    75781 atccgtaaca acttttcttc ctttgtcatc tgcaacagca gaaataactc ctttaggttt
    75841 gtacaataaa tagtaaccgt attcttcttg ataaattggg acttcatcca cttccacagt
    75901 gtcatgtttc ccaactttta tccctaattc ccttacaact tgtccgttta cttttacacg
    75961 tcctgcaagg atgaattctt ctgcttttcg acgagaagtg atgccagcgt gggcaattac
    76021 tttctgcaat ctctccatta caattattct cctttattca ttccatcaaa gaatagatct
    76081 ggtgacacgt cttcttcaag tgaaatttcc atttcttgtg tatcaggcag ttcttctaat
    76141 gatttcaaac caaaataatc taagaagtag ccagttgttc catataatat cggccgacct
    76201 ggtccttcta ctctaccttt ttcttcaatc agtttatggg cagctagacg ctgtaccgct
    76261 cctgaaacct gaactcctcg aatctgctcg atttcagctc ttgtgattgg ctgtttataa
    76321 gcgatgattg ctaaggtttc gacggcggct tgagataatg tgtttgatgt cccttgcgca
    76381 tatcgcttaa gtaagggagc cagctctttt ttagtcgtta atacataatg gctttccgtt
    76441 tcaaaaatat gcaaagctga gtgcgagttt tgagtgtaag attcttttaa ttctttcact
    76501 aaacttgtga cttctgcttc gctgagattt aacagtccgc ttaattcttc attactgatc
    76561 ccttcctcgc caacaataaa aagaagggct tcaagttcac ttaatttcgt catgttcggt
    76621 atctcctact gctggataaa gcataattga ttcatagttt tctttttgtt gcgcaatgat
    76681 ctgccctttt ttcatcaatt ctagcaaagc cataaaagta gtgacaactt cacttttaga
    76741 aggtgactca aaaaaagaat cgaaagtaca gccatgcgca tttcttttta tacgctcttc
    76801 gataaatacc attcgttctt cgatcgttgt gtcatcgggc gtgatcgttt tttccacttt
    76861 ttgagaaaat ttcttacgtt ctaagatttt ctgcatggca cggatcaaat cgattttttt
    76921 gacttgtcct cgcttcaacg gcttttcagc atccgctaac ccatcgatgt tcataggttc
    76981 ttttgtgtaa taaagacttc gttcctctgc tttttctgtc agtctttcag ctgcatattt
    77041 atatttacgg tattctaaaa gctgagtgac caattcttct cgaggatctt cttcccataa
    77101 ttcttcatcg tctgtgacga attcttggac aggaagcaat gtcttgcttt tgattgccat
    77161 caatgtagca gccatcacta agtattctcc tgcaacagct agctcgagtg ttttcattgt
    77221 atggatataa ttcatatatt gctccgtgat cgtagcgatc ggtatatcat atatatcgat
    77281 ttccatttgc tgaatcagat gaagcagcag atcgagagga ccctcgaata catctaattt
    77341 aatattgatc tccgtcaact cattcactct ttcttctttt tctttgctag ccattttcca
    77401 atgtaaggct ctgtgatttc agttgcacgg atggagacat ccgggtactt ttcctgtaat
    77461 tcatctaaca tttgaaagcc catattctca ccgcgataag acggattcaa agaaatgtca
    77521 tggatgatca gctgatcgtt cgttgcccag taaataccaa taatcccttg aatgttggtt
    77581 gaaccttctg gcgtaaagaa aaaaagttca taatcgtctt cagattcgta cgtatcaatc
    77641 tccttcaaca aagaagtttt acctgtcagt ttcttatgga aactcaatag tcccatagca
    77701 attttacggt tttctttccg gtaatgtgtt aacatcttct caccttccta tgactaagcc
    77761 cttggaaaat gctgcttata aacatccgtc attcttttct tcgtgatatg tgtataaatc
    77821 tgagtcgtag agatatccgc gtgacctaac aattcctgta ctgtccgcaa atcagctcca
    77881 ttttctagca gatgtgtggc aaagctatgc cgcagcgtat gtggtgttac ttctttgtaa
    77941 atcccagcct ctcgtactaa ctgcttcaga tttttccaga ttccttgccg agaaagacct
    78001 ttcccatgat tattgacaaa tacatgcatt tcagatgcgt cctttacaag taatggacgt
    78061 gcttcgtcta agtagcgttc cagccattgg atcgcataat cacctaaagg aatgatccgc
    78121 tctttatctc cttttccaac tgtctgtacc agtccaagag aaagatgaag atctcccaat
    78181 ttcaatccaa tcaattcact gacgcgcatc ccagtagcat acatgacttc caagattgca
    78241 cgatctctta tccctaacgt ttttgtcgta tcaggtgctt caatcagctt ttctacttct
    78301 gtcagagtca atgtacttgg taatttctgt gctttcttcg gcgtatcgat atgttgcatc
    78361 ggatcatgat cagtgatacg ctcttgccgt aaaaactgat ggaatcttct gagacttgag
    78421 atcatccgag taacagttgc tgtcgctttt ttttcttcat gcaacttctc cagaaaacgg
    78481 atgactaaaa agcgatcgac atcctgccat gaagcaattt tctgctcctg tagaaaatgc
    78541 aagtactgtt ccaaatcacg ttcatagctt tgtcgtgtat tggcggacaa tccccgttca
    78601 atattcaagt agtggagata atcgttgatt tgctctttca taataatccc cctcatgcct
    78661 ctctatcata tcagataccg cttcattctg atagtctttt tccataatct ga
//
LOCUS       DAFENC010000010        68212 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.010, whole genome shotgun sequence.
ACCESSION   DAFENC010000010
VERSION     DAFENC010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 68212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68212
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.010"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..2387)
                     /gene="esp"
                     /locus_tag="LP493_000881"
     CDS             complement(<1..2387)
                     /gene="esp"
                     /locus_tag="LP493_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HBL2133047.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAGEGTSIESGTTVFAVKDGVS"
     gene            complement(3005..3439)
                     /locus_tag="LP493_000882"
     CDS             complement(3005..3439)
                     /locus_tag="LP493_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133048.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(3456..4661)
                     /locus_tag="LP493_000883"
     CDS             complement(3456..4661)
                     /locus_tag="LP493_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HBL2133049.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            5355..5741
                     /locus_tag="LP493_000884"
     CDS             5355..5741
                     /locus_tag="LP493_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBL2133050.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            5835..6025
                     /locus_tag="LP493_000885"
                     /pseudo
     CDS             5835..6025
                     /locus_tag="LP493_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            6539..6871
                     /locus_tag="LP493_000886"
     CDS             6539..6871
                     /locus_tag="LP493_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL2133051.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            7167..7322
                     /locus_tag="LP493_000887"
     CDS             7167..7322
                     /locus_tag="LP493_000887"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HBL2133052.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            7598..8938
                     /locus_tag="LP493_000888"
                     /pseudo
     CDS             7598..8938
                     /locus_tag="LP493_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(9179..10795)
                     /locus_tag="LP493_000889"
     CDS             complement(9179..10795)
                     /locus_tag="LP493_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBL2133053.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            10913..11131
                     /locus_tag="LP493_000890"
     CDS             10913..11131
                     /locus_tag="LP493_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2133054.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            11326..11787
                     /locus_tag="LP493_000891"
     CDS             11326..11787
                     /locus_tag="LP493_000891"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL2133055.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(11980..12219)
                     /locus_tag="LP493_000892"
     CDS             complement(11980..12219)
                     /locus_tag="LP493_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2133056.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(12243..13766)
                     /locus_tag="LP493_000893"
     CDS             complement(12243..13766)
                     /locus_tag="LP493_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HBL2133057.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            complement(13784..13906)
                     /locus_tag="LP493_000894"
     CDS             complement(13784..13906)
                     /locus_tag="LP493_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBL2133058.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            complement(13936..14919)
                     /locus_tag="LP493_000895"
     CDS             complement(13936..14919)
                     /locus_tag="LP493_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HBL2133059.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(14943..15092)
                     /gene="rpmG"
                     /locus_tag="LP493_000896"
     CDS             complement(14943..15092)
                     /gene="rpmG"
                     /locus_tag="LP493_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBL2133060.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(15113..15490)
                     /locus_tag="LP493_000897"
     CDS             complement(15113..15490)
                     /locus_tag="LP493_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133061.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(15522..15701)
                     /gene="rpmF"
                     /locus_tag="LP493_000898"
     CDS             complement(15522..15701)
                     /gene="rpmF"
                     /locus_tag="LP493_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBL2133062.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(15716..15985)
                     /gene="rpsN"
                     /locus_tag="LP493_000899"
     CDS             complement(15716..15985)
                     /gene="rpsN"
                     /locus_tag="LP493_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBL2133063.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(16508..18274)
                     /locus_tag="LP493_000900"
     CDS             complement(16508..18274)
                     /locus_tag="LP493_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2133064.1"
                     /translation="MQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(18234..19988)
                     /locus_tag="LP493_000901"
     CDS             complement(18234..19988)
                     /locus_tag="LP493_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2133065.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLIKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(20098..20667)
                     /locus_tag="LP493_000902"
     CDS             complement(20098..20667)
                     /locus_tag="LP493_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HBL2133066.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(20685..22100)
                     /locus_tag="LP493_000903"
     CDS             complement(20685..22100)
                     /locus_tag="LP493_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBL2133067.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            complement(22111..22779)
                     /locus_tag="LP493_000904"
     CDS             complement(22111..22779)
                     /locus_tag="LP493_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBL2133068.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFATSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(22909..23493)
                     /locus_tag="LP493_000905"
     CDS             complement(22909..23493)
                     /locus_tag="LP493_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL2133069.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLI
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(23824..24057)
                     /locus_tag="LP493_000906"
     CDS             complement(23824..24057)
                     /locus_tag="LP493_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HBL2133070.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(24072..25022)
                     /locus_tag="LP493_000907"
     CDS             complement(24072..25022)
                     /locus_tag="LP493_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBL2133071.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(25019..25861)
                     /locus_tag="LP493_000908"
     CDS             complement(25019..25861)
                     /locus_tag="LP493_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBL2133072.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERSL"
     gene            complement(25863..26582)
                     /locus_tag="LP493_000909"
     CDS             complement(25863..26582)
                     /locus_tag="LP493_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBL2133073.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKKLKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGE"
     gene            27274..27432
                     /locus_tag="LP493_000910"
     CDS             27274..27432
                     /locus_tag="LP493_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2133074.1"
                     /translation="MNKKQTCAFLGIDNNTLDKWIRIYNFPVIRVGGVVRFDVEDIKD
                     FMNTFKIT"
     gene            27504..28730
                     /locus_tag="LP493_000911"
     CDS             27504..28730
                     /locus_tag="LP493_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL2133075.1"
                     /translation="MPTKLSNGKYKTNLRYPKRFKEITGIASEKYQKTFPNRQLAIKA
                     ENDMKKKIEKVLREENANSLELKGKITFKKFYESKWLPRYELGQTIRSNRPPSDITIS
                     NTKDIFRLHILPMFGEYAMNYLNINTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQSITAPKKNALEEKRIQEGKQALSSKELTNWIEAVNDDFNNHLL
                     TFHDYTLFMITLYLGDRKSETYALQWKYIDFEKQTVRLKHTLDKYQRKKFTKGRKDTV
                     IQVPEVVMTLLSEWKSVQADQLLKLKIKQTLDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPDLVHLSPHKLRHTYATIARQGGADMNQISNALTHSDISTTKIYVNTPDIV
                     DKAVFEAFQRGLNKCD"
     gene            complement(28818..29210)
                     /gene="rpsI"
                     /locus_tag="LP493_000912"
     CDS             complement(28818..29210)
                     /gene="rpsI"
                     /locus_tag="LP493_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBL2133076.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(29226..29669)
                     /gene="rplM"
                     /locus_tag="LP493_000913"
     CDS             complement(29226..29669)
                     /gene="rplM"
                     /locus_tag="LP493_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HBL2133077.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(30188..30655)
                     /locus_tag="LP493_000914"
     CDS             complement(30188..30655)
                     /locus_tag="LP493_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HBL2133078.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(30775..32313)
                     /locus_tag="LP493_000915"
     CDS             complement(30775..32313)
                     /locus_tag="LP493_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HBL2133079.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            32393..33079
                     /locus_tag="LP493_000916"
     CDS             32393..33079
                     /locus_tag="LP493_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBL2133080.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(33280..33807)
                     /gene="msrA"
                     /locus_tag="LP493_000917"
     CDS             complement(33280..33807)
                     /gene="msrA"
                     /locus_tag="LP493_000917"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBL2133081.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(33891..34568)
                     /gene="pgmB"
                     /locus_tag="LP493_000918"
     CDS             complement(33891..34568)
                     /gene="pgmB"
                     /locus_tag="LP493_000918"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBL2133082.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(34565..35695)
                     /locus_tag="LP493_000919"
     CDS             complement(34565..35695)
                     /locus_tag="LP493_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBL2133083.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(35695..37878)
                     /locus_tag="LP493_000920"
     CDS             complement(35695..37878)
                     /locus_tag="LP493_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBL2133084.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(37875..38900)
                     /locus_tag="LP493_000921"
     CDS             complement(37875..38900)
                     /locus_tag="LP493_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL2133085.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(38945..39772)
                     /locus_tag="LP493_000922"
     CDS             complement(38945..39772)
                     /locus_tag="LP493_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBL2133086.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(39769..40836)
                     /locus_tag="LP493_000923"
     CDS             complement(39769..40836)
                     /locus_tag="LP493_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HBL2133087.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(40862..41698)
                     /locus_tag="LP493_000924"
     CDS             complement(40862..41698)
                     /locus_tag="LP493_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL2133088.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(41695..42564)
                     /locus_tag="LP493_000925"
     CDS             complement(41695..42564)
                     /locus_tag="LP493_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2133089.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(42634..43917)
                     /locus_tag="LP493_000926"
     CDS             complement(42634..43917)
                     /locus_tag="LP493_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBL2133090.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(43931..45616)
                     /locus_tag="LP493_000927"
     CDS             complement(43931..45616)
                     /locus_tag="LP493_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HBL2133091.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            45891..46916
                     /locus_tag="LP493_000928"
     CDS             45891..46916
                     /locus_tag="LP493_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2133092.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(47511..51185)
                     /gene="rpoC"
                     /locus_tag="LP493_000929"
     CDS             complement(47511..51185)
                     /gene="rpoC"
                     /locus_tag="LP493_000929"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HBL2133093.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVKETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(51243..54860)
                     /gene="rpoB"
                     /locus_tag="LP493_000930"
     CDS             complement(51243..54860)
                     /gene="rpoB"
                     /locus_tag="LP493_000930"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBL2133094.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLFALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            55588..56556
                     /locus_tag="LP493_000931"
     CDS             55588..56556
                     /locus_tag="LP493_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL2133095.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            56574..57479
                     /locus_tag="LP493_000932"
     CDS             56574..57479
                     /locus_tag="LP493_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2133096.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGSAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            57476..58282
                     /locus_tag="LP493_000933"
     CDS             57476..58282
                     /locus_tag="LP493_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2133097.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            58418..59407
                     /locus_tag="LP493_000934"
     CDS             58418..59407
                     /locus_tag="LP493_000934"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HBL2133098.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMMTSESTMKDAK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(59724..60248)
                     /locus_tag="LP493_000935"
     CDS             complement(59724..60248)
                     /locus_tag="LP493_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HBL2133099.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            60535..62289
                     /gene="scm"
                     /locus_tag="LP493_000936"
     CDS             60535..62289
                     /gene="scm"
                     /locus_tag="LP493_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HBL2133100.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDT
                     SASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTS
                     ASSDSTDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSS
                     TTSDTRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVI
                     LLVIGLRITFMSYKKSKR"
     gene            complement(62444..63430)
                     /locus_tag="LP493_000937"
     CDS             complement(62444..63430)
                     /locus_tag="LP493_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBL2133101.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(63453..64019)
                     /locus_tag="LP493_000938"
     CDS             complement(63453..64019)
                     /locus_tag="LP493_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HBL2133102.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(64033..64449)
                     /locus_tag="LP493_000939"
     CDS             complement(64033..64449)
                     /locus_tag="LP493_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBL2133103.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(64906..66840)
                     /locus_tag="LP493_000940"
     CDS             complement(64906..66840)
                     /locus_tag="LP493_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBL2133104.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGKSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            67121..68077
                     /locus_tag="LP493_000941"
     CDS             67121..68077
                     /locus_tag="LP493_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HBL2133105.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
BASE COUNT        20751 a        13785 c        11533 g        22143 t
ORIGIN      
        1 aagcttacgc cgtctttcac tgcaaagact gttgttccac tttcaatact tgttccttcc
       61 cctgcggtga aggttacttt gtggtagcct gcaggaatgt tttctcctgg attttcataa
      121 atatctttac ttacagttac tgctaaatcg gtcgtgccta cagaaccatc ttggtaaaca
      181 attttaatag gaattgttcc agtaatcggc tccgattctc ctacaccttt agctggagtg
      241 aatgtaacaa taccagtgtt tgcatcaaca cttgcattac cgaagtactt attatagaca
      301 tctgaaattg aaaaggcatc tttagctaaa ggaacatctg gtttatcaaa tgtaggtttt
      361 ccactttgaa ctgtcgtttc tggagttgtt gttataggta cgtatgttgc atcattttcc
      421 atagcttgag aagcttttac agcaaactct acatccacgt cgaaagttcg atttccgatc
      481 ttaacagtta caataccttt cgtactatca gtaacgttag aagtatcagg ctctgttttc
      541 catgaatact ctgcatcttc aggtaagttt ttattattcc gaattgattc tttagcatct
      601 ggtttaaatc caactaccac ggtttgttta tcaaccgctt ttggtgattc cttaataacg
      661 gttgaacctt cttctggttt atcaaaacct ggagaaacga tttggatttt taattcatct
      721 ttcgcgatta atttacttga atctacaccc gtaaattcaa attctacagt atctgaaatt
      781 ggagccccat ctttttcatt tggagcgata gttttttctg ctaatacagt accttcttta
      841 tcaacaagtt gggctttgtg acctgttccc gctaactcgt ggatgaatac tttcccctta
      901 actgttgtgt caacatcata tacttcttct aattcaggtt tcccgatata tggattcgtg
      961 tctccgctct cttctttatc gtcagggttt ccatcaccat caatatcttg caaataataa
     1021 taacctgttc cataagtgtt ctggattaat tttttattcg tatccgacaa ccaagaatca
     1081 aagatgaaat cttcaccaaa tggtttattt tcttcaactt gtgctgttgc tttcatatct
     1141 tctaagattt catctaatgg cttagtcaat tgtaaaacat atcgaataac gactggacgt
     1201 ggacttgcat tagcaaaatc gataagttta gttaaatcat tattagttat tgaacctatg
     1261 ccataatttt catgaccttc ccgtcgctcg attgctaaat cagctacttt tgttccggat
     1321 tcaaacgaaa catcatatgt tactttgtca gcctgaacca tgtgcatctg tatacccgct
     1381 acatatggaa ctaatcgttc atcaattttg taattagcat accaaggcgt gccctttgcg
     1441 gaagatgaat atgagaaatt ataatttttc gttaacttat gatctaagat tatagctcca
     1501 ttagcacctg tggatcctga accatctttt gtttgagtat taggtttctc atattttgca
     1561 cttactgatc catgtttaaa ctggtcagga ttattttcag atacatctaa gctattatag
     1621 aaatcatctg aatctgttaa aaagtagccc gtactatcaa tacccggtac aattttatca
     1681 tcgtcttgat gacttaccaa gtagattcga tacattaaac gatcggtctt gagattgtct
     1741 atgcctatct ctttaaaaat ttcatctagg ctcttttcaa acgtaattac cccattagga
     1801 gcggtttgcg tatcggttgt ttctgcccca gcaaataatc catcacttgc acgaatataa
     1861 ttgaccttcc aaatatttgt aggtctaccc agcgaatcat taattcttac aaaggtccgt
     1921 ctagaagatc caattccttt ctttggatcg acctgaattt tttctacata tttagctaat
     1981 cgttcatcta attgaagacg gatttcccag tttttagttg atgctgcaat attatgtttt
     2041 ccgtaaactt caaatccaat tgtattgcct tttagtgtgt ctccagttag ttcttgagga
     2101 ctaaattgta aatccgaaaa gttataattt ttcgtataac caggattctc ctgaaaagta
     2161 ttccccgaag ctactttgtc acctacttgt acggagctta tcgctgtttc aagtgggctg
     2221 cttggagaaa tttcatcttg tgctttaact agttcagttg ttcccaagac aagaccaaca
     2281 ccaatcaaaa cagatgcaac cccaacactt aattttttga tactgtactt caatactcgt
     2341 ttctttgttt tttctagaaa tactctctta ttattcttgc taaccattat tcaaatcaac
     2401 tcccttaata attactttcc tagtaagaat aaaagataaa tctgatacgt attattcaca
     2461 gaataggaat cttactaacc ttatgttaac taatttactt agagaatttc atgaacatta
     2521 caacaaaaaa aagtacattt cttcatgttt ttttcggata tttgtgcttt ttaaccattc
     2581 agcagctgaa aacatataaa aagatatgta tgtattcttt ctgaaattaa gttcatttct
     2641 atgcgatgaa gcatgttttc aaaatattac cctttcttag attaaacttc agagtattca
     2701 aataacggaa taaggagcct tatcccgcat tactgaatga gactgtgaca taagtaaaaa
     2761 ggtgacttca aattccttct tcggaatttg aaatcacctt ctttataatt ataaagtatc
     2821 ggtttcacag catttctgaa tgattcctag aatcttaaac gaatgattgg agttatcaac
     2881 attttttcac tcgtttttag cgaaacaaaa aatgacattt gtcacagcct cattaaatta
     2941 ttgattcttt ttctttataa ttgaattgtc catatttaaa gtgtctagta ctctacatga
     3001 ataattaatt gctttcactc aaatacttat aatctattaa cttgtagttg tttaactttt
     3061 ctgaaaaagt tagacccacg taataatctt cccagctttc tctttcaatt aactgatcca
     3121 atttttgata atccataaat tcatcatgta tcaaaaagaa taaataactt gatattttag
     3181 catctagctt aatcagatta aataatgttt gtttaaaatt gctaccatta atatgactga
     3241 tagattctct agcttcttca cataaacttt ttactttatt aattactact ttgtcatatt
     3301 catttaacac actattatta ccattactta gacgctcaga ttctacgaaa caactcaaat
     3361 cagaaatttc ccaaaaaaat tttttgttaa aatccaattt cctcaactcc tccaaactac
     3421 gtaaatgata tagtctcata ataaaataaa acctctcagc taatgttgtt gaaattgtcc
     3481 actaaaccta attgatattg cttaggagat acacctgcgt actttttgaa tactctcgaa
     3541 aagtgtgaag aatctgaaaa tcctaaacct aaagaaactt cactgatagt atggtttgat
     3601 ttcaacatta ttttagccgt agaaattttt cgcttagaga tataattata aatcgtaata
     3661 tgcatttcat tcttaaagct ttctcttaat ttagtttcac ttacagaaaa ataattagct
     3721 atttccttta cagtaattct tttatagata tttaagccga tgaattgaac gacagaagaa
     3781 attaagggag aaagatgctc tatcttagtt tttccgattt ccttagtata ataaacaatc
     3841 ccagaatccc tcacttttaa gacctcaggt aacgatacag ctaattcgtt ttcttgtatc
     3901 aaagcatctc tactttgata cgcttctatt atatccattc ctaatgttat agacgtttgt
     3961 gctaactttt caaaaacaat gatagaataa tttttttcag accgaatcgt atctccacta
     4021 acacttggaa ttattccatt actcagatta aaaaccatgt tttctaaatt tcgaatatct
     4081 ccatttttaa catattccag tattttattt tcataaagaa acagatatat ttctggatcg
     4141 taattttgtg ataacagatt atctattttg atttgctcga tagttttact tagattttct
     4201 gtatattcaa ttaacggttc atggaataga tcttctattt ttccagtaaa aaaataatga
     4261 actaaaatca gaatatctcg aatgtctcct aaagaataca aagtcaaatt ttgcaatgaa
     4321 ttatagagtc gttctctatc agccattgca acattcaaat tgttcatttt tagtttaaaa
     4381 aaaactttat caatattatt tgctctaaat ggaccaaata agtaatatct ggttttaaac
     4441 atgtatagaa gaaacatctc attaaaatca ccagtaaaga aatggaaatc tttagttttt
     4501 ttaatattat cagttagtaa ctttttataa tcataaaaaa aataagtagt tctatctgag
     4561 cgatactctt ttataatact gaattcggaa ttaaaaacca cgataggtaa ctttaaacaa
     4621 acatgaagag actttaataa gacttcttta tctgaaaaca cttttgtttc tctctttcct
     4681 ttctacatca ttaaatagta ttttatacgt tatctaaaat actattcctc tgtcaaaata
     4741 agctaactta cttcattata aaatatccac ttatcgcttt catgtatatt ccaccgtaaa
     4801 aagtacattt tatcaccgag aactcatcat ttttcatcat gatgaatact atttacatat
     4861 atctagttca aagacaataa ttattatgat ccgttattat ctaagcacta tacagataat
     4921 aggaattttt cgtttctaaa tattccaatt tgggaatcca ataaaaattt tcgttcaaat
     4981 acgtgtctat tcgaactctt ttctagttgt taattatgaa gggggaagaa ataaaaaata
     5041 caatctatac acgaataaga atattatcca aaaggaggtt ttagaaaaga tttattatac
     5101 gtaaaaagct caagacattt tcttagccat aaggacatgt ttgatattta agaagatata
     5161 tgaattttct tttctaagta taaagataac tatccattat caactaaaaa aacatttttg
     5221 aaaataaaca tcagcagtcc tatcaatgca tgtgagctta tagaagttat tcgcagcgca
     5281 gcataattgc attagcttct tttcgtgttt tttgcctctt ttccctttaa atcttaatgg
     5341 aggaggtgtg caatatgtca gataacgacg aacgcgtaaa tgcccagttg attcgattct
     5401 ttgaaaaggt cattttgaac accgctaata cttattataa aaaacaagaa gaaattcaaa
     5461 aacatgaaca acttgatcaa ctcccaccat atttgtttac taaagatact ataaaattta
     5521 aacaaccgat taatgtttta aatgtgactc tccttgttga agatataaaa ttagcaaaaa
     5581 tccttccttt gttgaaagaa cctgaacaaa tttttcttat cgaaaaattt atctttgata
     5641 aaactgataa agaaattgga aaggttctgg ggattacaag acagggtgcg acaaatttaa
     5701 aacatcgact ttacaaaaaa attcaaaaaa tgctggttta atatctgcat aataactaat
     5761 tttgtatgct tctttgctcg ttctcctcct tcccaaagaa atagattata agtccatggg
     5821 aagaaggtag atttatgaat tctttaaaag aagatttcat tttagcaaag gctggaaatg
     5881 aagaagctgt tgaggcaatt ctcaaaagat ttagctcttt gattcataag caatcctgag
     5941 aactggaaaa tatgatcaag attgttatca agaatgtatg cttgcaatat atctagctat
     6001 ctcgaaattc gaaattaaag aataactcaa ctaagggagt ctgtgacata agtaaaaaga
     6061 tagtttcaaa tttcgaacaa taaatttgaa actatcttct ttataattat aaagtatcga
     6121 ttttacagcg ttctataatg attcatagaa tctaaaacga atgattttaa ttatcaacgt
     6181 tttttaattc gtttttagct taaaaataac ttttgtcaca gtctcactcc taaaattact
     6241 ttatttacgt atgaagtggg caggaggtcg aatccagaac tgggctatgg tacttcaacg
     6301 aggacttctc ctctagaatt gaaaagcatg cgatttacct tccgtaacga cggtagattt
     6361 attcaactat gtgtccaatc aaaatttgtc tgatttcaaa aatagtcaag agaattttgg
     6421 ttgttaaaaa ctcttatcta tcaacttcca cagtttagtt gacaaaccct gatactaagt
     6481 tgggctatga tacacttttc ttgactatca gttacgttac cggaaggaat gaactctatt
     6541 gagaaaaaca tatgatcgta aatttaaact aaagatttca caggatatcc ttgagaaaaa
     6601 agtaactacc aagaaaattg ctgaagaata caatatctct cgtccaacaa tttcccgatg
     6661 ggtttcagaa tatcgtcgat acgggaaaaa tgcttttgct ggacaaggaa aaagattacc
     6721 tgataaagca gatttctaca ttcttgaaca ggaaaataaa cgactaaaag aggaagacga
     6781 gtgttctacg aacacaaaga tcgatacgga tctccaggga tcactcaaaa actttacgat
     6841 gaaggaatcg aaatcaataa acgtgttgta gctgttctta tgcgtgaaat gaatttatgc
     6901 acaagaggat ttcatcgacg caaatcttct catggtagag aaaaaacaat caaagaaatg
     6961 gtaaaaaaat gttgaatcga taatttgaac agaaccaaat tgatgctgtt tgggtgatgg
     7021 atattactta cattccatgt aatgacggtc gcctctattt gtccacctat attgacttag
     7081 caactcgtat tctacgttac tatatggtag attcacacat gaaaaaagag attgtcgtcc
     7141 gtccattaca aatttattaa ggagaattgc ctacggtaat tcattccgat agaggtagcc
     7201 agcatcggtc ttttatttat caagagctgt tgaacgacca ccacatcaca cattcagtga
     7261 gccaaactgg gactcctgtt gacaatgcag taattgaagc gtttcatcga tcaatcaaat
     7321 gagaattaat cgactccaac aaatataaaa gtaaaataga gatgaaggtg ttaatccaag
     7381 attatttaga agactactac ccaaacaaaa gaatccatac aaaatttatg atgactcctt
     7441 gacaatttga agcgaagaaa ataagggatc tataatatct agtgttggtg acgccttctg
     7501 ttgccaatac tttttctttt ttctaataaa cgcaaacaga caccttaaaa tcctttagaa
     7561 taaagtcgac gaaaaccatt caaaggagtg tttcaagatg tcctattcag agtttaccaa
     7621 agagttacta gatattctag acctaaatct tatctttcat gaagatgcct ttcgcaaaga
     7681 gcgaatcaat gacgaaacat gttttgtttt tgatggcaca ttgacctatc aaccggagga
     7741 atgctttcat cgccactatc aaaatgaaca aacgatcatt aaatagggct ggaaaaaagt
     7801 atccatctta ttgaatgatg tcagtaacta caagaccatt ctgcggatta acaaacagcg
     7861 cttcaaatgt aaacactgtg gaaagacttt tttagcagaa gattcagtta gtgatcgtcg
     7921 ctgctccatt gctcgcagag tcaaacaagc cattcttgag ctattaagcg aacctctttc
     7981 tatgtctttg atcgcacgta tgaagcacat ttctccgacc actgtcattc gaatacttcg
     8041 cagccttcgg cctaaaacca tttctttgag ccagctgtta ccagaagtgg tgtgtttcga
     8101 tgaattcaaa tcagtgaaaa atgtctcggg agccatgagc tttgtcatga tggacggcaa
     8161 gacccatcaa ctgattgata ttgtggaaaa tcggcaactc aatcctttac gcgactattt
     8221 cttgcgctac cctataaaag tccgtgaaca agtgcgtcta gtggtttcag atttctatac
     8281 accctatcgc acattggtga aagagtgttt tccgaatgcc cgaatcgtcg ccgatcgctt
     8341 tcatattagc caacacattg gtcgggcttt taccaaccac cgaattcaag taatgaagac
     8401 ctttaaaaaa ggggatcgtc ggtcgaagca cttaaagaaa tactggaaac tacttcaaaa
     8461 gaatgcgtgg gaattgaaag gtcagcatcg ctactggcgt ccgtcatttc gagatcatct
     8521 gacagaagca gagatagtcg atcggctatt atcttatgat gattccttaa agcgaggcta
     8581 cgaagtctac caggattttc tttccgttat cagaagacaa gatgttcctg aattcgtcgc
     8641 gctcctaaaa gaagactaca aggagttgcc agagcactac caaccagtgt tcacgacctt
     8701 caagaaatac caaacagaaa tcaaacgagc gttgcgcgtt ccctattcca acggccctat
     8761 agaatgtttg aataaccata tcaaagtact aaaacgaatt gcctatggct atagaaactt
     8821 tcaaaactac cgagaacgaa tctttttata tcgaggaaaa tattttaaga aaactaagaa
     8881 tactacccaa ctgactaaag ccagaacaac aacacggcta gacaagatag ctgtctagcc
     8941 gtgtgagtat ctcgattatt ctattgaatt tcttcaccaa cactcattga cgaagagcca
     9001 aaataagtaa tctaaccgac tgttaactaa accattgcag gtcccgttaa agatacttgt
     9061 gcctgttgtc accgcttctt tttcttgtcc acaagcgctt aacacactta ataaagcccc
     9121 tgctattatt aataataata tctttttctt attaaaaacc tcctcatcta tttccagatt
     9181 agtaaatgta gtaatctgtg ctttcttttt tctcaatact aataactaac ttatggggta
     9241 aacaaatact cgtttgaccg ggttttgaga tccatccagt tctaaccgcg atttgatcag
     9301 gactattatc ttctttaact cgaattcttc catctttaat ctcaacaata ttatattgtc
     9361 ccttcgcagg atgataattc acgagtttat gattgatctt atccaaatcg aagcgatcca
     9421 tttccttgcc atcaattcga acgatggcat atttgatagc atcttcagtt gtttcattct
     9481 ccttttctat agagaataca aataagggaa taaaagaggt aataatcaaa atgccaataa
     9541 ttatgacatc gcctatcttg acaccagctt ttcttaaaaa tttcattaac gatatctggc
     9601 taaacatatt agactttttc catggaaatg gtgaaatttt tcggaaatta tctgcattaa
     9661 gagaatcagt taaacaaccc tcaagttgtt ccttaataca ttgttgatcc atcttcatac
     9721 caataaaaac tagtttatta atgcgttcac caaacaacgg atgccaggct tccttcaatt
     9781 cgggattttt ttgtataatc atttgacact caattttagg taaactagct acccaataat
     9841 ttaatgattc aatactttta tagctacccg atgtttcaaa gatcgtcgaa aaatcactat
     9901 gttgggcaaa ccaaagaaac ccttttgctc ttgtaatatt gccaggaaaa tttttatccg
     9961 taagatgggc aaatttttgt gcgtcaagga gtaaccgatt tcgatagata aaacttgaga
    10021 taccatattc ttctgtttca ggaatatgat tttgatagcc aagctctaac tctttgaacc
    10081 agcccactga ataggaagtc tcatctatat taaaaagatt tgtatttaga attttcgata
    10141 agtctacttc acctttaatt gtcctaatta ttttggcatt ggactgtaac ttagcaatta
    10201 gaccgttaat tttgtaaatc gtcttggttg acactaagtc actattattt aaaagtaata
    10261 tgttacaaca ctcgaattga tcaattaaca agccacgaat atcctgttct tcttcaacta
    10321 cattaccttc agcttttctt tcctgaatct tttcacccgt ttcgaaatta tcccaaaaac
    10381 gttttacatc cactactata ataatggcac caatctctaa tcgttgggtc aaatcaatgt
    10441 ctaaagggtt tttagctaat ataattgctt gaataattgg aattggtttg ctgattcctg
    10501 aagcttcaat aacaatttga ttcaagtcag aaaattgcac taattgatct agttcaacaa
    10561 tcaaatcttc gcgtaatgta caacaaatgc atccattcgg catcgaaaca agtttttctc
    10621 cagttctttt aaaacctttc ttgtcgacta ataccccatc aacatttact tcccctatgt
    10681 catttacaat gacagcaatt tcctttccgt gatcaccgta cagaatatga tttagaagta
    10741 tcgtttttcc tgaaccaaga tagccagtta agattgtaat aggtattttt ttcataggga
    10801 acctctttct ataccttgaa tttacacttt aagtgcaaca cataaaaatg agtcataatc
    10861 gatatccaac tagtataagt ttgtcgagaa cactcctaga aggaaaataa ttatgagcca
    10921 gtatcgtcat cttactatac tcgaacgaga aagaatcttt ctgcttcacg aagaaggatt
    10981 ttctattagt ataattggca acgacattca gcatagcccg tttactattt tacatgaact
    11041 gagaagaaac aagaaaaaaa ctattcacct tccaaagcgg aaaaaaatta tgcttatcga
    11101 agaaaaaaat gcggacgtta tcacattcta aatgatccgt gagtttggtc aattgttcgt
    11161 catttatttg tcgattttca gtggtcgcca gaggaaatct cgaatcgttt gaagcatgaa
    11221 catatggact tttcaattag ttttatcacg atctaacgtg caatttgcaa tgatcttttc
    11281 gatacagaac ccctctcaca cggcaataaa ggcctgatcc gttcattgca ccatcgagga
    11341 aaaacaagac atacaaaaaa tcatgtcgag tctcgtggaa agatttgcct tactcattcg
    11401 atccatggcc gtccaaaatc cgcagatgat agaagtgatt ttggtcattg gaaagccgat
    11461 attgtagctg gcaaaactgg tggtacttgt ttagtgactt tgacagacag aaaatcatgc
    11521 ttccttttag caggaaagaa ggtccccaga aagaaagccg cttatgtgag cgagaaaatg
    11581 attgaacttt taagcagtat tccaaatgag gcggtcaaaa cgatcactcc agatagagga
    11641 aaagaattct ccaatcattt cgcagttaca gaagcattga ataatatgcc cttttatttt
    11701 ccagatcctc atgcccttgg caacaatgaa caaattaaaa tacgaataga ctcattcgag
    11761 aatacttgcc aaaatcgaaa gagatagcta cggtagataa ctcaacgata aatcagatga
    11821 ttgaaaaact gaataacaga cctagaaagt gtttagattg gagaacacct tatgaagtct
    11881 tctttgataa agtgttgcgc ttgatttgac aattcaagac ataataaaaa gcagatcaaa
    11941 tccaaataag ggaaaaatga tctactctgg tattatcaat taattggcca agctattatg
    12001 ccgttttgct aaacgtctac ttcttccagt attgaccttg ataaaacaac aatcaggatc
    12061 ccgttttaat actctatgaa ctgtgtcaat actaacatgt aaagttgcag caatatcagc
    12121 taatgtactc ccatttaatc tcatttgctt tgcaaatcga taacgccgat aagcatcaat
    12181 attcttggaa tccatagaca ataatacttt tcttaccatg tatttcctcc aaaaattgaa
    12241 ttttaatgag ccatcatttc ttgagcaatt tcatgtttag acaatgaagc tggatagaaa
    12301 gtaggccaat tatgcaattc attatagagt ttttcttgac tttctccacc aaagaaaata
    12361 tggaaatgct ctgccttact tggtgcaatt ccatgatcac taaattgaat atatttaaaa
    12421 cgaccagcac ctgcatcatc agtttcaaaa ttaaaacgaa caccacggtt tcctttttca
    12481 taattcaaaa ttttgtatcc aacatatttg tatgtgtatt gatgatgttc accgttgact
    12541 acaaaatcaa tggtgttgtc tttaatgttg atagtatcaa tatctgtctt atagccagta
    12601 gtataataat ctttgtactc ggcagctgtc atgtctttat tgatttttgc tttgtaatcg
    12661 aaaacttcat ccaaaattcc atcttttaac aacggataaa cagattgcca ttcgcctgta
    12721 taatcactca attcgcgatc cttcacatcg gcatctttaa agtacccatt agcaactgtc
    12781 ttttcatcct tcgcttcttt ttctggaact acctcttcac cagcaaccat agttgttttt
    12841 tctaacgctt ttagattgtc ttccattact gaaacataat cttcaccatt atccatttgt
    12901 tcttttgtaa gactttcaag aggattcagt acttccaatt ttatcccagc ttcgttggcc
    12961 aaagtttttg caattttatc attagcattc ttttcaaagt aaatataatt gatcttattt
    13021 tttttaacat actcttttaa ttcagctaat cgaccagaag atggctcttc ttcaggactt
    13081 agtccagcaa taggaacttg tttcaatcca taatccaaag ctaaatatcc aaaggctgcg
    13141 tgttgcgtca caaaactttt ttgtttcgct tctttaagac tagtggtata gtcagcatcc
    13201 aaccgtttca gtttagtcaa atacttttca gcatttgtct caaatacttt tgcttttttc
    13261 ggatacaatt taactaactg atccttgata tttgaaactt ccttaattgc cattttgggt
    13321 gaaacccacg tatgaggatc tagttcatga tggtgatctt cttctccgtg atcatgatct
    13381 tcttcttcac tacctggcaa taaaatcatg tcttttgttc cttctactac attaggccca
    13441 gctttcttcc aactttcttt agcttttggt acccatgatt ccatgttttc gttatgatat
    13501 acaaaaacat cagcatcatg agcttttgcc atatccttag ctgagggctc atagtcatga
    13561 ggttctgatc ccgctggaac cattaaatcc acgttcgctt catcgccgac gatgtttttg
    13621 gtgaaatcat acattggata gaatgttgtt acaatttcta attttccatc tttatcattc
    13681 gatacttttg catcattagt gctggagcaa gctcccaata atcctagagc tgctatccca
    13741 ataagtccta cactgatttt cttcattctt tttccttcct taattatgct aatttcttca
    13801 ttttatttcg tttatgttct ttgataattt ttaatgccct ttttctagtt ttaatattcg
    13861 ggcttttaag tcgtcgatat gcactagata tatccgtttt ctccattaga aattaccccc
    13921 aatcactact tatcattatt tgctttccgc cagtaattta tcaaaactct gtttgatcct
    13981 ttcttcatcc aacatttttc cgattagaat aatagtggtt tggtcttttt gtcgagtggt
    14041 gtattgaaaa ttaacctgtt cgtttacctc ttgcatggca actataaaat cctgctcttg
    14101 taaagcaatc aatcctttaa aacgatacag gctcccttgg ttggttaaaa tcagccagtc
    14161 aatccattgg agtaaaaaat ctttttttat gtcttgatct gaagttaaga gaattgattt
    14221 aaactcatgt acttgatggt gttgatgata gtatttgcca ttatagtgat tttctgatga
    14281 atcactttca aaaactaagg gatgattaaa ttttttcaaa ttataaaaat cctttttttg
    14341 aatcgtttca ctatgtgtga acattcgaat atcggataaa gggttaatac ttttgatttc
    14401 tctctgtaat ttttttagtg cagataaatt caagttttgt tttctagaca caaaaatgcg
    14461 atctgccatg acaagttgct taagggcttg tggttctctt tcaataagtt caaaactgtc
    14521 actatcaata acagtcaata aactatcgat atatactctt cctcttagtt gaggcgctgt
    14581 taaaagtgtt tgaatgattg gttggggatc tgctatacct gtagtttcaa tgatgatttg
    14641 tgaaattggt tgttgatgtt cttctattgt ttccagtaaa gaaatcaata ttgctaataa
    14701 atcactgcga agactgcaac acatacatcc attatttagt tgtaacaccc gttcctcgct
    14761 atgaactaat aatttgtgat caatcccaac ttcaccaaac tcattttcaa ttataataat
    14821 ttcttccctg gggtagggtg agacttgcaa ggcttgattg attagcgttg tttttccagc
    14881 ccctaaaaac ccagaaacga ttgtaactgg tatgcccatt ttgtcacctt tttaccactt
    14941 agctatttca cttctttaaa aattgcccgt ctgcgcaatt ttggcgaata cttttttaat
    15001 tctaaccgtt cagggttatt ccgtttattt ttgctggtga gatacagacg ttctccagtt
    15061 tcgacacatt ccaaaataat attttgacgc ataaatcttc ctccttcaat acttatcgat
    15121 cttcaagata tgcttgaatt tgttgtgcat cttcaaaagt taactcgcca gattccaatt
    15181 gtgaaactaa attttctttc atatcaacag gtatctccca ataaccatcg atacattgaa
    15241 ataactcctc gtcatactct tcaaaaattg gatagattct taaaaaatca tcaaatgata
    15301 agccttggtc ctcatagtaa tctttgacta atccattttc aattgcctgt tgggtcggta
    15361 aacccgtttc agtaataatt cctctctcta ccatcgaacg ataaaaagtg catttatcta
    15421 gcgattgctg ggtcgtttca agataatact ttaatccttc ttcaactaaa ggtgggtaaa
    15481 taatttccat tttgattccc tcctaaaagt tatatattaa actattttga agctccttta
    15541 attactttct ttccattata gtaccctttt aaagatacat gatggctacg tctataatca
    15601 ccattcgctt cgtcaaatga aatttctggt tttactacag tttgatgagt tcttcttaac
    15661 cgtttcttcg ccttagatgt ttttcttgct ggtactgcca tgatatttcc tccttttacc
    15721 aacttgcttt ttttactcca ggaatcaacc cttgatgggc aagttctcta aacttaatac
    15781 gggacatacc gaactttcgc atataccctc ttggacgacc atccgtctga tcacgaagcc
    15841 tcagacgatt cggatttgaa tctcttggca atttagcgag agcggtgcga tctcctgcgg
    15901 cttttaattc ctgacgttta tctgcatact tttcaatcat cgccatttgt ttctttgctt
    15961 tagcaatttt cgactttttt gccatatacc tttatactcc ttttattttg atttagacac
    16021 ctcaaatcgt aatcgttacg ttttgacact gatactttac caacaagagt tgctcttgtc
    16081 aacaataaat aacatgaaat aaaactcata tgaatagata actatttgaa aacgaattta
    16141 tcggtacata gagataatca aatcatttaa aagaatatgc agtttaggct ctgaaaaata
    16201 agaattcact tttattagtc caatcaaaca caaataccgt tttaagtagc ttttcctcta
    16261 cttaaaacgg caatatgaaa gaaactataa ctttttattc aatcttttat gtttaactgg
    16321 tttatcgcca attttttaaa actttgatta ttccttatat tataagaata gacattaagt
    16381 gaactaattc aatcatactg attctttcgt gtattcaaaa ttagatgctg tttaataaaa
    16441 ttattctttt tgaaaaagaa ttataactat atcccaaaaa ttgtaggtta atttaaagcc
    16501 tatttcatca tcgtgattga gcttcttttt catagacgaa tttctcagat agtttagttt
    16561 tctttatgag atttttgtat atttctgacc ttcgatacaa ctcattatga gtaccttgat
    16621 caactagttt tccttgatcc atcactacaa ttttatttac cttttcaata gacttcaagc
    16681 gatgcgatat aattagtact gtcttatctt gtattaaacg atttaaactt tcctgaatac
    16741 gtttttcatt ttccgcatct aaactggcag taatttcatc taaaattaaa attggcgcat
    16801 ttttcaaaaa agcccgtgct atggataggc gttgtcgctc tcctccagaa agtgaacttc
    16861 cgttttctcc gaccaatgta tgataaccgt caggtagttt ttcaataaag tcttcgcagt
    16921 tagctaaacg agctgctttt ttcacttcct catctgacgc ttgactattt ccaatacgta
    16981 tattttccaa aatacttgta ttaaacaaag ttacctcttg aaaaacaata gcgattttgc
    17041 taaacaaaga agctggagat acacgtttaa tatcataccc atcaattaaa atacagcctt
    17101 catcataatc atacagtcta gacactaatt tcaagatact agttttcccg gaaccactag
    17161 cacctactaa cgcagtcact tctccttgtt tagccgtaaa agagatatga tctaaaattg
    17221 gggtattgtt atcatatgag aaagagacat ctcgcaactc aatgtcaaaa gatttcagag
    17281 gactatctga tccctcttgg atactggttt ccttcatagc tctaattcgc tgtattttag
    17341 gagctaaata aaatatttca agcactgctt ctttcataga atcgaaggaa tcctttattt
    17401 ttattgcggc tagtaagtaa ccaacgacgt agagtatagt cacttcaccc gttaacagta
    17461 agtgaacacc tactagaatg actactgcta aactaacata tgagaaaata gaggataagg
    17521 ccatgactga aaaagtactt aattctacct ttaaatgaat cctttcactc tcttccattt
    17581 ttttgaaaag tctgtcttga acttttttag atagattaaa gctattaatc tcttgctgca
    17641 attctatagt ttcttgaaat tcttccgagt tttctctcaa agtatcgtaa tatttagtat
    17701 tggctttcgt ttgggatttc tttgataaca agattaagac aaaactaaat aacgttggca
    17761 aaataacagc taatcccatt ttgacattac caaccaaaag catcactgaa ataaaaggga
    17821 aaaacagagc cataccgccg gctttaggta ttgcatgact catcgcatgc tcaatacctt
    17881 caacgtcaga catgatagtt tgagataaat ctgataaatt atgttttgaa aaataggata
    17941 atggtaaatt tgacaaatcg tctgcaattt gcactcttaa atgcgcactt tctttataag
    18001 tactattata taagttttca tactccctat ctaacaacca atacatgaaa agcaaagtaa
    18061 caaacgatac ggcaaaataa agccaacggg gctttgtatt ttctaaaact aattcgtcta
    18121 tcagcatcat tataatgaat gctggtacca tattaatgca gtatacaaaa aaactagaaa
    18181 tagaagcttt agttaaagct tctgcgccct gatcacttaa agcaaatttg tttttataaa
    18241 aacttttcat tgtcaagcct ccaatcattt gcattctcat aattagtgac caattgttta
    18301 tacacttgat gtttagccat taattcatta tgatttccac gttctactat tttcccttct
    18361 gacaagacaa gaatttcatc tacagattta atgctggata atcgatgagc tatcataata
    18421 actgtttttt cttttatcag atgttgaaaa gccttttgta gttcatactc attatctgga
    18481 tcaatagatg cactggcttc atccataata acaatctttg catcttttaa aattgctctg
    18541 gcaatagcta tacgttgttt ttctcctcct gacagataaa ctcctttact accaattaag
    18601 gtatgctctc tttcgggaaa tttttctaaa atcgattcgc aaccggctaa tcttagcgcg
    18661 tcaaatactt tacttgctgg cgcttgagga tttgctatag aaacgttatc gtaaatactc
    18721 tgattgaata gtttcgtatc ttgaaagaca aaagcaattg tgttaataat tgtgtctttt
    18781 gaatagtgat ttaaaggctt accaccaatt ttaatctgtc ccttatccac attgtagaaa
    18841 cctgaaatta gtttagctat cgtactcttt ccgcttcctg attttcctac taatgcataa
    18901 attctttttt gttctaaaac taagttgaaa ttttctaaaa cacactcttc tttgtatgaa
    18961 aagctgacat tttcaaatgc aatgtcacaa tttttaatct gtgtctcgtt cccatatttt
    19021 agttggtctt gcttcatttc taaataaagg gagtctagtg tttcgactgc atatcttgct
    19081 tcaaacaagt gcatacttac atacattatt ctcatgaaag aaacaaaaat aattccactt
    19141 aaaaaaaaca acatcaacaa gtcaacagct aatatcttgg gagtggtaag agaagttata
    19201 aaaaaggtta taggaactat caaaatgcaa actatgccaa aaaatagcca ttgaaaaaga
    19261 acaaaaggtg ttttcccact caaagaatac ttatatgcaa acttagcata atcgttaatt
    19321 gctttattca aggctttaaa tgatgttact ttagcaccaa atatctttat aacttgaatt
    19381 ccgcggatat attctaccgt ttcagagctt aacacatcta acgattcttg atatttttga
    19441 ataaaatttg tattctctgt cattttcttt aacaagaata caccaattac taacatggcg
    19501 attagaacca atccaatttt aaagttaatg aaaaagccta aggcaactga taaaacaggt
    19561 gttactatgg cttgagcact atctggaatc aagtgagcaa ttgccatatg tgttttagcc
    19621 gcgttgtcat caattgtctt tcgaatatat cccgaagaat ttaaatcaaa aaaacgaaaa
    19681 cttgcttctg ttaaaccgct aattcccttt tttctcaaat tagtctctaa gcgaaaccca
    19741 aggatatgag aaaataagcc agaaaaaata taaaataaag ctcctaaagt taaccaagca
    19801 acagtttgaa ccgcataact cttagctaaa tattcatctc ctacaataat tagagactga
    19861 agaaatttgt aaatactgta atatccatag actgttaata cgacagaaaa atcagaaaat
    19921 aaagtggcta accatccgta gtatttcatt ttagggacat aactaaataa ttttttgtat
    19981 actttcattt tttcctcccc cgcattcaat ttcttctctt attcgtttac aactgttaat
    20041 gctttccgta atagcgtaaa ttagagatgt acaaacagat aaaaggtaaa ctacgttcta
    20101 ttttttgtat ttttttaaga cttttcttcc aatcaataca ccaatcatag ataaacttgc
    20161 tacaactaac actgaaatga ttccccatat acctaccgca tagtggatca ttgcatccat
    20221 tgttgcagca gattgtcctt tatctatcca atcttgacga aaacgatctg taaagaacca
    20281 tataggaatc cactgtccgg cagcactgcc taattgcatt agagcccaag acgcaacttg
    20341 aggaattgct cgatcatatc caaatacaga tagaataata tcagctaaga tcgccatact
    20401 aatcgaactg ataaaccaag gtaagtacgc cccgcccatt aacgtaaaaa ataacaataa
    20461 aacaattgtg taaatagtaa aaattccttt tctagggtag ttatagctaa tataaacaaa
    20521 tatgattcca gataataatc caaaaatccc gggggatatg ctgtgaccaa acgccccacc
    20581 aatactacta accattattg aaaaaaagta aattactagg gaaataactg tagctaaacc
    20641 aataaaaata taatcttttg ttttcatata tattctcctc aattctattt cgttatgtca
    20701 ttaaaaatct gttctatcaa agttgaatct tctactctaa gttttatatc tttttttatt
    20761 ccaccatttt ttaaataaat aattctattg catgttttat aaagaaattc cggatcatga
    20821 gtagctataa ctactgcacc cttttctttt aagtctttaa taaggtcagc aatcctttcc
    20881 atattaatat aatccaaccc acttgtaggt tcatcaaata gaaataaatt agtttttgac
    20941 aatgaagcta tagaaaccaa taatctttgt ttttctccac cggataaatc aaacggtaat
    21001 tgatctttca ttttataaag ttccattttt tttaaaattt tttcttgctg atctttacta
    21061 actatttcat tccccagggc taactcgctc ctcactgatt ctgtgaaaaa ttggtaatcc
    21121 atttcttgca ttactaaaaa cggcgatgac aaattttttt tattttcgat tatctttcct
    21181 ttggtagggc gaataatctt catgagtatt cttagtaagg ttgttttccc cacaccgttt
    21241 ttccctacca aaccaataac atctccaact ttgacatcaa aatttatgtc ttttagaata
    21301 ttttcataag taatttcttc aacttttaat acatctgcac ttaccttttc gatataggga
    21361 acttcaatcg aactattaaa aatgtcaaat ttccttaatg cgttattgtt ttcagttttt
    21421 aacaactgaa tagttgtagt ttttacagtt ctatttttaa caaatagaac ttgatcaatt
    21481 aattctttca aatagtaaaa acgatgttca gctataacaa tagtaaatcc tttatttttt
    21541 aaatcacaaa gtaagtcagc aagtttctta gtcgctttga agtccaaatt tgaagacggt
    21601 tcatccaata taattaattt agagtttagc gataaactac atccaataga aattttctgc
    21661 cgttcaccac ttgatagcga aaaaatgttt ttatctaata tatttgaaag atctaataat
    21721 tcagctaatt cattgattct tttatccata tgctcttttg taaatccaaa gttttccatc
    21781 gaaaatacta actcactcgt tgtatttgtt gtaaagaatt gtcctctagg atcttgactt
    21841 acgtagccaa tattttttga tatactttct tgtgttaagg attgtagcga gttattttca
    21901 aataaaattt ccccaaccaa ttttccgtca taaagtcttg gaataagtcc attcattaac
    21961 tttaatagtg tggatttccc actcccagaa gaaccagtaa tcaatgtaag actgcctttt
    22021 tttattgaaa aattaaggtc aacaagcgct tgttccttaa catccttata tgaaaaagaa
    22081 acattgttaa attcaaacaa ttctttcacc tcaaatcaaa atacttaaga aaaaaatagt
    22141 aacggaaaac aggatgatat agtctaataa gctcatgttt gttttatagt aagaacttct
    22201 tttcacagga gattctatcc cctttgttat tgcattagcg gtcatttctt cagcaatcat
    22261 agttgcacgt ataagaacgg gaactaacag aaattccaaa tattgcagag gctgaaaaaa
    22321 agacaagcga atgtttctca tttttaaaga ttctttaatc attcttattt cagaacgata
    22381 agtcggaaag aatctgatca ctactgtaat acttaacatt atttttttcg gtaaatgtat
    22441 tttttctaaa gaggataata attcattgct agtatagaca ctaaccaaca accatgagat
    22501 cattacgacc ggcaacattc gaaatacaat atataaggat gtcgcaaaaa atatagtaaa
    22561 aaactctatc ttgatagcat caataatttt cattactaaa aacagaactg aataaatcaa
    22621 gatgaaataa atacatgtct ttattttacg aaacatcaat actaaaactg tagcaataat
    22681 gaaacacccc acttgaaata tatttccctt tcctaaaaaa ataatgaccg gaaaaaaaat
    22741 atttaaagta atcaaggtta acggattgat ttttgacact ctttcacctc caaaaaataa
    22801 gatcgcactg ttatcttaag ctgataaaaa tgcaccgtta ttcagataac agtgcgatct
    22861 tatcaaaaag cataactgag aacaattctc aatgcaagct ttttttaatt aactcagtaa
    22921 ttcaatccac ccaggaacag aaaattgata caatcttctg gttaatagca tagtcttttc
    22981 ttttgaatag ctatgcttca atatatcata gaatgtagcg tagaatgagt aaatgtagaa
    23041 gtggatttct tcttcattaa agactaaatt ttgattgatc attccgatag tctttaactt
    23101 atctagacaa cagactgtct ttttcgtcac aaatgatgta attttttcaa caatatcttg
    23161 atatttggtt ccagctgatt ggaataaaat caaatcgaat atacgtttat tctcaaaaat
    23221 ataattaata aatggatcta attcattgaa gttctctctc caacttttct ctatatctat
    23281 attttctaag tttaagaggt atttggtaaa ctcttcatta tacatattaa taagcgcatt
    23341 aatatgcggc tgaataattt cttcaaataa cgcttcctta gaagtaaaat gtttataaaa
    23401 agcacccgta gttacgcctg cggtcaggca cagttgcctt atcttagttt gctgaaatcc
    23461 ttctttttca aaatggctta gtccactttc tattaacttt tggtgagtta taatataatc
    23521 tctggtttct atgggtactt cctcctaata agatgaatta actttattat cttacacagg
    23581 acttgaagtt tcaatcgtta acgtttatta ctgaactcat tccttagagc taaactaatg
    23641 agaaagagca gaataactga tacaaaaagc aatcctacaa gaattaatag actcatctaa
    23701 atcattcacc ttttctaaaa taatccgaga aagatttaaa aaaattatat ccagctatta
    23761 ggataagtcc tatcataatc actccaatag ccattttctt atcctcccta aaaataaagt
    23821 cttttactta aaaccttttt tgtaatcgtc aataaatttt ttccctttat cagttaattg
    23881 aaatcctata tctaaatagt cctcatatct aagtttagcc agcatctcac ttacagatgc
    23941 tggactaaca cttagaactt ttgctaaatc attatttttt aatttctttt ttctttttga
    24001 taattcctga attgctagta aataaattag tatagtagtc gttttaattt gtaccatacc
    24061 taccctccaa attatttcga aaggccttca gcaattttat ccaggttcca tttcatcatc
    24121 gcatagtaac tatcaccatc ttgtcctttt tctgcaattg aatcagtaaa aatcgttgaa
    24181 tagataggaa tattggtatc ttttgatact gttttcattg gtctatcatc cacactgctt
    24241 tctacgaata aggagggaac ttttgttgtg cgtaattttt caactaagtg ttttatttga
    24301 tctggtgttc cttcttcttc agtgttgatt tcccaaatgt aagcagaagg cacattatac
    24361 gctttcgaga aatatttaaa gcatccttca cttgtaacaa tcattttttt atcattcgga
    24421 attgaagcaa atttagattt agcttctttg tctagagaat ccaatttttc aatatactta
    24481 tctagatttt ctttatagaa ttttttatta tcaggatctt tttccgctaa ctgtttttca
    24541 atatttttag cgtaaataat accgttttct aaatttaacc aagcatgagg atcttccttc
    24601 cctttctcac tctgaccctc taagtaaata acatctatgc catcacttgc tgcaaaatag
    24661 tctttgtttt cctctttgtt cgcattttta actaattttg taaaccaagc atttcctcca
    24721 gtttccaagt taacaccgtt ataaaaaatc aaatctgctt ttgaagtttt ttgaacatct
    24781 tcaggcaaag gttcatattc gtggggatct ttcccaatag gtacgatact gtgtaaatca
    24841 attttatctt ttgctatatt ttcggtaata tctgctaaaa tcgaattagt aactactact
    24901 tttaattttt cgttcgaagc cactttatct ttgtctttac tatttattga acatgccccg
    24961 aatataaaaa gagcaatcaa aatccccaga cttcccagta ctgctttcca ttttctcatc
    25021 ataacgatct ctccttcttt cttaaaaatt tttgttttgg tgagattaga aaactaatta
    25081 caaataagaa tgccgctgtt aaaacaatac ttgatcctgc tgctatgtta aaactataac
    25141 caataaacaa tccaagcaat gatgaacttg ctccgactgt tgcagaaata aatatcatag
    25201 ttttcaagct atttgcatat aaatatgctg tagctgctgg tgtaattaac attgcaacaa
    25261 ttaatatagt tcccacactt tgcatagctg ttactgctac taaagttaat agaaccatca
    25321 atagataatg ataaaaactg acattcatcc ctattgcttt tgccattaat ggatcaaaag
    25381 aagtgattaa taattcttta aaaaatagaa ctactataac caacactaaa accgaaacgc
    25441 caattgtaat ccacttatca atatcttgta cagctaaaat atttccaaat aaaatatgaa
    25501 ataaatccgt tgagctattt gcaactccta taaggataac tcctagtgct aaaaaagaac
    25561 tgaaagtaat accaattgct gtatctcctt ttattacact attgcttttt ataaaagtaa
    25621 taatgataga agctaataga ccaaatacaa tcgcaccaat aaaaaaatta atacctaaaa
    25681 tataagaaat tgctactcct ggcaaaacag catgagaaat agcatcaccc ataagagaca
    25741 ttcctcttaa aataataaaa caacctactg ttccagaaac aatccctata actacagatg
    25801 taattagagc attctgtaaa aagtgaaagt catacagacc attaataaaa ttttgaagca
    25861 tattattccc cctctccaat aaatatagta tctccatagg ctttttttaa attttcttca
    25921 ttaaatacag attctacact tccgtgagca attagatttc gattcaaaag aataatatta
    25981 tcaaaatact tctttacctt gcttaaatca tgatgcacaa ttagcactgt ttttccctga
    26041 tgtttcaatt tttttaacgt atccataatt attcgttcac taactaagtc tatccctaca
    26101 aatggttcat ctaaaaatat gaaatccgca ttttgagcaa gacatcttgc taaaagtaca
    26161 cgttgaaatt gtcctccaga taattctcct atttgatgat tagaatattt tcccatatcg
    26221 accttttcca aagcctttga aactctttgc cattctgcat ttttaattct ttgaaaaact
    26281 ttcattccgg catatgttcc catagataca cattctttta cttttattgg aaaagtaaaa
    26341 tcaatatcag ctttttgctc tacatatgca atcttcacca gttttttatt gatatcttca
    26401 ttattaatgg agacctctcc ctgatgaggg ataatattta acattgcttt aagcaatgtg
    26461 gattttccag caccatttgg accaataata cctgttaaag caccttcttg tatttttaaa
    26521 gaaatctcgt tcaatgctaa aaaatcgtta taacaaacat taagcttttt cacttctaac
    26581 ataactttct ccttctaaat gataatgatt atcacgatca tatggtatac aaaaattata
    26641 ttttagtcaa ccctaaattt tatagtttag atttttttct gttgctgaag attagaatga
    26701 caaaactatt tgaaactacg cgtatagtaa gtagctttca aaatatataa aaaaggagcg
    26761 ttctcaaatg agaacatgct cctaaaacta ctttattggc gtatggaaaa attatacttg
    26821 aagtggatag cgggttgaat aagttgataa gcatcaaaac atttataaaa attattcaag
    26881 actatgtctg ttccatatac aaatatgaaa atcagtaaac tccatttaac ttttttcgta
    26941 gtgtgtcttt ttatacatgt ttatcgttat taatagtgaa taggaaaaaa actatttttg
    27001 atcattgaca attaaataca atttttgaat aacgatccct gctattcgag ctagaaactc
    27061 aagtacgcca tgacctgatt agcgacaaat acttagagat ttctttttgt tctgggaaaa
    27121 caaaatgcca tgacaatagc agcaaataat gatacttccg taaggctcgc cgtaaactgg
    27181 ggagaggtga aattcctatg tgcttaccca aagcaattca aaaatttcat aactactatt
    27241 ttaggagatg attttataga atccagagtc tacctgaata aaaaacaaac ctgtgcattt
    27301 ctaggaatcg ataataatac tctagataag tggattcgta tatataattt cccagtaata
    27361 agagttggtg gtgtagttcg ctttgacgta gaagatatta aagactttat gaatacattt
    27421 aaaataactt gaaattttct tctcgccgca tatactaaaa ttagtgaaat atactgcctt
    27481 acttttttta aggagtgagg attttgccta caaagctttc aaatgggaaa tataaaacta
    27541 atctgagata tccaaaaagg tttaaagaaa taacaggaat tgcatcagaa aagtatcaaa
    27601 aaacatttcc aaataggcaa ttggcgatta aagccgaaaa tgatatgaag aagaaaatag
    27661 aaaaagtttt gagagaggag aatgcaaact cattagaatt aaaaggaaaa ataacgttta
    27721 aaaaatttta cgaatctaaa tggcttccta gatatgaatt aggtcaaaca attagatcaa
    27781 acaggcctcc tagtgatata accattagta atacaaaaga tatatttcgg ttgcatattt
    27841 tacctatgtt tggtgaatac gcaatgaatt atctaaatat caatactgag ataatatcag
    27901 atgaattaac caaaaaatcg aaagaatatg caaatataaa aatcataaaa ggatatgttc
    27961 gttccatgtt cgatattgca gaaatactaa attatatcga atttaatcga actactaaaa
    28021 ttattcaaag tatcactgca cctaaaaaaa atgctttaga agaaaaaaga atacaagaag
    28081 gtaagcaagc actatcatca aaagaactta ctaattggat agaagcagta aatgatgatt
    28141 ttaataatca tttacttact tttcatgatt acacactttt tatgattacc ctgtatcttg
    28201 gtgatagaaa aagtgagact tacgctttgc aatggaaata tattgatttt gaaaaacaaa
    28261 cggtccgtct taaacatact ttagataaat atcaaagaaa aaagtttaca aaaggtcgaa
    28321 aagataccgt cattcaagta ccagaagttg taatgacatt gctaagtgaa tggaaatcgg
    28381 tacaagctga tcaattgttg aaattaaaaa ttaagcaaac gttagatcag tatctcttta
    28441 cttatactaa accatctgga gaagtaaatt gtcctgttca tgccgattac ctaaactatc
    28501 gaatcaattc aattaaaaga aggcatcctg acttagttca tttatctcca cacaaactcc
    28561 gtcatactta tgcaactata gctagacaag gtggagcaga tatgaatcaa atttcaaatg
    28621 ctttaacaca ctcagatatt tctacaacaa agatatatgt gaacacacca gatatagttg
    28681 ataaggctgt ttttgaagct tttcagagag gattgaataa gtgtgattga tatgtgttct
    28741 taaatgtgtt cttaaaaaca aaagaagcac tttccaaata attgaaaagt gccagaaacg
    28801 ttgatatata aaggatatta acgttttgag aattgtgaag ctttacgtgc tttcttaaga
    28861 cctggttttt tacgttcgac catacgtgcg tcacgagtaa gtaagccagc acgtttaaga
    28921 gctaaacgga agtcaggatc aacttctagc aatgcacgag cgataccatg acggatagct
    28981 cctgattgtc cagcgtatcc tccgccgttt acgttaacaa atacgtcata tgcgcctttt
    29041 gtttcagtaa cagcgaaagg ttgattgatt acttcacgca agtcagcatg tggaatgtat
    29101 tcttcaacat cttttttatt tacagtaatt ttgccagttc ctggtactag acgtacgcga
    29161 gcaactgcgt ttttacgacg gcctgtgccg atatattgaa cttgtgccaa tgaaattccc
    29221 tcctattaga ttaagtttgt gatgtctaaa acttctggtt gttgtgctgc atgtggatgt
    29281 tctgctccac cgtatacgtt caattttgta aattgtttgc ggcctaaagt gtttttagga
    29341 agcatacctt ttacagaagt ttcgatcaaa cgacgagaat ttttagcacg caattcgcca
    29401 gcagtgattg atttcaatcc tcctgggtag ttgctgtgac ggtaataaat tttgtcagtc
    29461 gcttttttac ctgttaattt cactttgtct gcattgatga cgatgacgaa atcgccagta
    29521 tccaaatgag gtgtgaaagt tggtttattt ttaccacgta gtacagatgc aacaactgtt
    29581 gaaagacgtc ccaatggaac atcagttgcg tctactacat accatttacg ttctacttcg
    29641 cctggtttgg ccatatatgt tgtacgcacg ttattttcct ccaatttaag ttctgatgtt
    29701 tgacatacac ttcgagtttc cggggctctt tgtggggcaa acaataccat ttaacatatt
    29761 acccgctaat ctagtcaatg tcaacgtttt tctgcttgat tgaaaaattt atatgaaact
    29821 ttacttcttt tctttctttt atataaaagg gtcgtttcct gtcaaaatga aaaacaaaaa
    29881 gaggctgtga caaaagtctt gtcacaaccc cttattttga ataaacggtg ttctcctgcc
    29941 aactcctcgg tcacaagtca caatatccat aaaacataag aagctgtttt ttaaaattgt
    30001 ttcttgtgac tcggagctga acggcaggct tacaacctct tggtaaacgg tgttcaatca
    30061 gctgaccctc ggtattagct caaaaaacgg caaaatatga ggaactattt tgacgtttgt
    30121 ttctctaata ctcaggtcaa aacgctgatt tcacaacctc tttttcggtc aagttcaaca
    30181 acagttttta cgcgtcgatc tctggcgctt tgcccaaatg agcttggatc atccagatac
    30241 gtttttctgt ggctgttttg aattcgataa agatatcttg tgttggatcg tcgccttctt
    30301 ctccagaaac ttcgattcct ttttggtaaa gatctgctag ataacgatag cctgcaacaa
    30361 gtgtttccaa acgttctgga atagtacgat cccagcggcc aatttcatca gggatttttg
    30421 tgttatctgc aaattcacgc aatgtagaat aaggtgaacc gtctaatgtg atcaagcgtt
    30481 cggatacttc atctaactga gcgttcaaat catccatgaa ctcatccatc attgggtgca
    30541 atgtaaggaa acctggtcct ctcatgtacc aatgtgtttg gtgaacaaca acagacattt
    30601 ggcttagatc tgcaactaat tgatttaata cttctttggt ttgttggaat ttcatctttc
    30661 ttgcctccta acattttctt acacttaaaa taatagtaga ctttcaatga aaagtacaac
    30721 aaaatcattt acctgagaac gattttcagt tcgctttttt atccgtaaag ccaatcattt
    30781 ttcagaatca gctaattctt ctcgcagttg agcaaattgc tgataagtct gtgctaaatg
    30841 cttttgtgtc gaaacaaata atggatagat tttctgatat tttttatgat cagtttcttg
    30901 tactccaact tgctctttca attctatcaa ttcctgtgct tcactgatac tttggatctt
    30961 tccgatgctt ctccagccta aaatcacagc tcctaatgcg gatgcttctg tgacagtagg
    31021 gaaaacaagc gggtaaccca gtacatcagc catcatctga cgaaaaatcg gagattgagc
    31081 aaacccgcct gtagcacgga tctctgtgag ctgattttcc tggcaaactc cttttaaaat
    31141 ccgataaagg ttgagacaga tcccttctag aatcgccttc atcatttctt tttctgtatg
    31201 ttgccgctgt aaaccgataa aactgccaaa cgcatctgcg tcccaaagcg gtgctcgctc
    31261 accaagtaaa tagggatgaa aaatcagacc attggcaccc gctggcacaa aagcgatagc
    31321 cgaaagcagt gcatcatatg gattttctcc tttttcttta gcagattgaa cgacttcctg
    31381 taaaaatgta tgccctgccc aatcaaagat gccagcacca ttgctagtcg ctcctcccac
    31441 tacccaatgt ttctgatcca gaacataaca aaacgtctcc atttctggat ggaactgagg
    31501 ctgagtagta ataaaacgaa gtgctccgct cgttcctacg gtcaaagcgg cgatcgtatc
    31561 accaaaagca cctaacccta gattagaaag cggcccgtct gcccctccca aaacaaatga
    31621 tatatcattt ggcaaaccta gttctgctgc tgtttttgat ggtagacctg ttacttgata
    31681 ggtggaagga aagacttgcg gcaattgctc tattcgaatg ttcaagtagt caagcacttc
    31741 ttctgcccat tggaattcat ggatatcaaa atatccagtt cctgaagctg ttccgtagtc
    31801 gctgatcagt tcgccaaaca atctataaaa gatatagtct ttgataccga caaaataagc
    31861 agtttttttg aataattcag gttggctgtt ttgcagccac ttgattttgt tcaatggtgt
    31921 cattggatga atcggcgtcc cagtctgccg ataaaattct ttgccaagca cggtatattt
    31981 cagtttttct gcttcgtccg ctgctcggtt atctgcccaa gtgatcattc gagataacgg
    32041 tgttttctct tcatccaaca atatcaggcc atgcatcgca gaggagaagg agacaaattg
    32101 aatgattgtg tctgaaggca actgtttaat tacttctttt ataacggtgc agacaccttg
    32161 aaagatcaat tcctgatctt gttctgccat cccttgtgtt tcttggatca aagggtagcg
    32221 aaaataagcg gatgctgctt cttgggcttc atctgtgaaa gcaactgctt tggtttgtgt
    32281 ggttccgata tctaatccga ttgaaacgtt cattttttca cctcaaattt tatgtatgta
    32341 caaaaattta gtttaagctt gcgtatcttg gttttgaaaa gggggagatg gcgtgttact
    32401 ttattttatc attggttgct gtatcggatc atttttatgt ttaaccgccc agcggattcc
    32461 gttaggtcac tctattattt atcctagatc tcattgtgtc aaatgctgtc gttcgctttc
    32521 ttggtatgaa ttgattccga ttctctcgat catcgtccaa cgatttcgct gccgctattg
    32581 caggtgtcgg ttgcccttct actatttgtt ggcagaagcc ttatgtggtg gtctttttgc
    32641 ctggttcttt actttttctt ccgcaagaaa tttttcgacg ttcatatgga tgctttcggc
    32701 tttgctattt tcgttgatgg atttatttta cttcatggtc cattctcaca cgctattctg
    32761 ttcttgggca attttatgga ttttttggtt gcaggccggc gtcttccaat ggcaaagtgt
    32821 gctgttaacg tttatcgtag gcggtgtgtg ccttcgctat ggtcaatcct atctcggagc
    32881 tggcgatact ctgttgatgc tttcttggag tggtggcttg tctctagaag agttgcttca
    32941 gatcttgttt cttgctagtc tgtttggaat atccgttttt tctgtttact ttatctgtca
    33001 taaaaaaaag ttggaaaagc tgcctttcat tccttttttg agcagtgcgt tgctgattgt
    33061 ccttcatctt aggtattgaa aaaaggttgt gacaaacgac ttgtcacaac ctctgatata
    33121 tagtgttctc ttaccaaatc cttgtgactt ggagctaggc gacaggttca caacctctcc
    33181 actaaatggt gttcaatcag ctgaccctca gtattagctc aaaatgctgg ttttacaacc
    33241 tctgatatac ggtgttccat aagtagcttt ttcggcttct tatttcttga cgccccaatg
    33301 tcgacgaagg aaacctgcac gtccagaacc ttctcgataa agattgtaat ggagcttgtt
    33361 tttcttgtaa taatcctgat ggtaatcttc tgcaggataa aattcgcttc ttggttcgat
    33421 ttttgtcacg attggcttat cgaatcgccc gctgtcttgc aatgcttgtt ttgaacgctc
    33481 tgcaatattt cgttcttctt catcattata gtagatcact ggacgataag aatcaccgcg
    33541 atcagcgaac tgtcctaatg cgtcagtcgg atcggtttgc tgccaataga tttccaccaa
    33601 ctgatcataa gaaataactt ctggatcata ttcgatctct actgcttctg tatgccctgt
    33661 tgtgcctgtt gttacttgtt cataagttgg atttggtaca tgcccgccag tataaccgga
    33721 tgtcacagaa atgatccctg gctgctcttc aaatggtttg accatacacc aaaagcatcc
    33781 gcctgcgaaa actgcttttt ttgtcatata aaatccccct tttttctcat cataccttga
    33841 tttccaaaag gaggataacg ttttgcttgt gacagaaaaa acggaaacta ttatatacgt
    33901 gatacggctt ctgataaatg ccaaaacgaa cgtacttgat caaaaacggt taaatcagga
    33961 atcacatatt cagcagaagg aagatttatg ttttcaccta ttcccaatac atgcatgtta
    34021 ccagccaaag ctgcttgaca accagcttct gaatcttcaa tgaccaagca tgcatttggc
    34081 ggtacattca attgctgtgc tcctttgaga aaaacttctg gatcaggttt tgcttttgat
    34141 acttgcgtgc cgtcaataag gacatcaaaa taacttgtca aattcgtttt ttctaaaatg
    34201 aggcgtgcat ttttgcttgc tgatcccaat ccgatcttga tgtttgtttt tttcaagtac
    34261 tcaagaacag ctattgcacc aggcaaaacg gatgtttcat ccattttttg aatcgcttga
    34321 agatatagat tgtttttttg ctcagcaaag gctgatttct ctttttctga gaatttctgt
    34381 tccatttttc caaatgacag caatcgctct agtgactcgg ttctggatat tcctttcagt
    34441 tgctcgtttt ctttctcagt gaatggaatg gacagctggt tagctaaaac cagccacgct
    34501 tcgtaatgat aacgagctgt gtctacaaga acgccatcta aatcgaatag tgctgctttg
    34561 attttcatcg attacctcct tgaaaatgaa cgacttgaag taaagatgcg atgtttttag
    34621 ctgtgcgatg aagattatca gtggcttgct gtaaagcttc ttgtaaaggc acagctgcag
    34681 gaaggatcgg aaaaacggcc gaaatgccaa catctgctgc tttttcgctt cctttaccaa
    34741 cacttccgca aatagctatc acaggaacgc cctctggtac tcttctagca atcccaactg
    34801 gcgcttttcc ttttagactt tgtccatcta gacgtccttc gcctacgatt acgaggtctg
    34861 cttgctgtac ccgtttatcg aactccagta aatccaatac gtagtcgatg ccagagacta
    34921 ttttccctga agcaaatgct aacagtcctg cacccattcc accaccagca ctactgcccg
    34981 atgcctcgat tacttgaggg gcaaatctca tataaaaatc atgcatggct tggtcagcca
    35041 ctgctaattc attttctttc aagccttttt gtggtccgaa aacaaaagaa gcgccttctt
    35101 ttccgcataa aagattagta acatcagtaa tgacagtgat tttggcttta atcagctcaa
    35161 taggcacgtt cgttttatca actgtagcaa ttttacctag attttctccc agtgcttcta
    35221 ctttttgatt atcttgatcg taaaaagcat aacctagacc ttctgccatg ccgatgccgc
    35281 catcgttggt actacttccg ccaacgccga tgatgatgtg tcgaacacct tgttgcaaca
    35341 attgtcgtat cagttctcct actcctcgcg tggataacct aagtggctgt tgttggttta
    35401 gtgggacatc tttcaatccg acgatttctg ccatttcaaa aatcgcagtt tgaccgtctg
    35461 aagcgtactg gatttctttg tttttgccaa atgcattagt aacgactgct gtttgccgct
    35521 tcaaccttaa actgtctgct aatgatgaaa ccgttccttc tcctccatcg cctataggta
    35581 gcagatcata ttcagcctga acaaaaactt cttgaaaacc tgattgaatg gcttgtgctg
    35641 cctctaaggc tgtcagactt tctttgaaag aatctggcgc aatcagaata cgcattattt
    35701 tcccctccgt tccaagatca gttctttttc cagctggtat tggtctccat tgacaaaaat
    35761 aggtaatgtt tctttcgtct ctttttttat tactatttgt ttttttgtca aaacaaatag
    35821 caacctgtga tttttccaaa taaaaggaaa agaaattttt tcccatgctg aaggaagtct
    35881 tggagaaata gaaagagttc cattcgttac tgtaatacct gaaaaaccaa atataactgc
    35941 tagccatagt gctcctaatg aagcagcatg aattccgtca tctgatgaat gcggatctgg
    36001 tcctaaatca atcaggcacg cttcttggaa taaatgatac gcccattcca tttcttggat
    36061 acggcaagcc tctatggcgt gaatcgcttt actcaacgat gagtcgtgga ttgttttgtt
    36121 ttcatagtaa tgcaaattct tagaaacgat tggttgagaa aaatactcag gtaataagta
    36181 taacagcatg acaagatctg cttgcttgct gacttggagt tcatttactt cgctacgggc
    36241 ataatcaagt aaaatagact ggctgccagg acgttctttg taagtggtca aatcaataac
    36301 tggcttactg agatacgtgt catcttgcgg aatcagctgt tctttgttag gcactggcaa
    36361 atataactta tctaaaaaat tttgacattc tttcaaaaaa agcggatcgc cagcttgata
    36421 tttaacagct aaggccacat tataatgcgc cagatagttc gtatatgcat tattgtcgat
    36481 atattctgtg tattcatctg gaccaatgac tctgtgtatc tctaaatgat catcgacttt
    36541 tacagctctg ctcagccaaa aagctgctgt ttcatgaatg agcgtttttc cctttgtttc
    36601 taaaaacgat tgatcctctg ttgcttggac atactcttga acggcataag caaggtctgc
    36661 actgatatga tgttctgcgg cagctgaagc aacttcttgt cttgttccgg ttttgatatt
    36721 caatgcagca aatttgggtg tctcttcctg accagtgtgt gcgctttccc atgggaaaag
    36781 tgcaccttga tagtgataat ctcttgcttt ttgccgtgcg ccttctaatc gatcataacg
    36841 gtacagcagc aaattctttg ctacttcagg aaactgatat aaaaagaaag gcaggataaa
    36901 aatttccgta tcccagaaaa catgcccttt ataaccttcg ccagttagtc ccttcgcccc
    36961 tacactaaca cttggatcat tgcggggagt cataatctgt aaatggtaag cagcgaagtc
    37021 catcgctaac tgatcgaaag aagaatcgcc ttggatcgtt atccgatgct gatgccaaaa
    37081 atctgtccaa taagacatcg actgctctaa aatttctgta taactaacgc ttttctgggc
    37141 ttgggcaata cttttcttaa acgggtctgt ttgctgaaga gaggtagaga gcacgatgat
    37201 cttctccagc gtaaaggacg tattttttct gatcttttct gaaaaggaag cggtgatccg
    37261 gcgatttttt gcttggaata cacctgcttt attgaattta gctgcaatcc caatatcaat
    37321 tttactttct gttgtctggt aggatgcact gatcaaatcg tcaccaaata ctcgcagttc
    37381 tttttcaacc aactgctgtg taccaaaatt ggtttgctgt ccatcgatac ccgttttcac
    37441 atctacttgg cagtcttcgg tcaacggctt gatgaccact ttcagggctg cctgatggag
    37501 attattttga tcagcaacac gacaagtaat gacttccact ttttttcctt gagcagtttc
    37561 aatgagcgca tagcgtttaa gctctcccat ttctaaatct agtgcccgct cgtatgcaag
    37621 aactttcatc gtctcaagag aaaaatgttc accgtcgatt tttatttccc atctgatgac
    37681 atctgggaga ttcactaact cggctgattc tgctcctaaa ggtcggttat atacaccagc
    37741 tgcaaacatt ccccttactt gattccgata gtcttcctcc tggcttcctc tgataccaaa
    37801 aaatccattt ccaatggtca tctgactcgc atacttattg atatactcta aatcaaactg
    37861 tttttcttct actttcataa ggtaataact tctcctgttt ctgccgaacg atataaattt
    37921 tccaccagat tctggatgac atatccttgc cagccatctg caatcatctg agtctggtca
    37981 ccgagcgccc gattcacaaa atgagccata cttagttcat gtgggtcatt aactggcgtg
    38041 gtcttttgta aggaaaccag ctttccatct acatcttcga atagttcgcc tggatacaga
    38101 ttagcacctg cctgatcgcc acaaaaagcc acattcagtt tgtcttctct gatattcaaa
    38161 gcaaacgaag tattcagttg gatgatcttg ccgttttcta attccagtgt gccaaaaatt
    38221 gcatcttcta ctgtgaattt gcttggatcc catttcccga atttccctga attttttttc
    38281 gtaccaattt tttggaagct gtacgcccga acgcttttta ctttaggaaa tccagtaata
    38341 tacatcgctg tatcaagcat gtgaatgcca taatcgatca aaggcccgcc tccttgaagt
    38401 tctttgtcga taaacgttcc ccagcctgga acaccagacc gacgaagcgc attcgcttct
    38461 acgtaataaa tatccccgag aacatcaaga tgattcttga tcattgttgc ttcgtcagaa
    38521 aaacgatgct ggaatccata agccaaaatc tgcccgtttt tatcggctgt ctctgccatc
    38581 tttcttgctt gatcagctgt catagctggt ggtttctcgc acatcactga agcattagct
    38641 tcgagggcag ccaatacatg ttcgaagtga aagcgattgg gtgtacagac actcacgata
    38701 tcgggagaaa tctcattcag catttgtgta actgatgtat acgcatgaga aaatcctgta
    38761 cgtcggcaaa agtcttctgc tcgctggctg actggatcaa ccacagcggc caattctaag
    38821 acatctgatc ttttttgata ataagcagca tgtacttttt ctgctacttg tccagcgcct
    38881 atgattgcta ctttcttcat ttatttctcc ctcctttgct tatttactta ttgttattct
    38941 ttctctattc tttctctaaa tcatttaaat gacgcgctgt ttccagacag tttttcaagt
    39001 attgcaatga ttcctgataa attttcactt cattttctcc tcgcaaacga cattcatata
    39061 ccatataacc ttcatactca ttttgaagta gcgtttgaaa atggcgagta aaatcaattg
    39121 cgccagatcc tggttggtag cgatgattat ctgctaaatg gatatgaccc acatactctt
    39181 tttgcgtagt caatgctttt gaaatatcat cttcttcaat attcatatga taaaaatcag
    39241 cgatgatctg cacatgtttc aattgattag agtcaatgta atgacgcgca tccgctaaca
    39301 aattgatcat atggtcttgg tatcggttca aaggctccaa ataaataacc gtacctgttt
    39361 cttcggctac tttatctaaa taacgaagtg attcgctgac tgctttatag tctccttctt
    39421 tgcttcgggg tgaaaccatc ggcggtaatc gataagtgaa cattccccaa gctgctggga
    39481 taacgattcc tttgcctcca acctcgctta gtgcacgcaa aatctcagca atttgacgta
    39541 caccattaag acgccgttct tcgataaagt caccgatcca cccatcgtag ccgttacaag
    39601 ctgtcactac tgggatccct gtttctttga ttgcctgttt gactgtgtcg atattttcta
    39661 ttaacaactt accgtcgatt tcgtattctt caaatccaca gtctttgata aatctaaatt
    39721 tttctaaaat gtctcttggg aaaaatgctt gatcttgcgt accgaatttc attgttctcc
    39781 tcctcggact tgaacgccca ttttgatact ttcttctggg tgctggtcta cataacgcat
    39841 gtaagcttct gcgctttctg caaatggcac aactggatca atgatttctt cacaatccaa
    39901 gtaaccgttc atcaataatt cccaacatgt gtcctcgatt cgtttacggt tccatcttgg
    39961 gtaatctggg tttggttcac tagatgctcg agcaaagacg atttttgcat tattgaaatg
    40021 tgcttcgcga ccaagattaa acccagctgg aaaaggttta gcaaaggcaa cataagaaat
    40081 gatcccgcca tagccgatcc ctcttaaaga agcttgtaat gcggcagcac tgccactcgt
    40141 ttcaataact gaatctactc cacgtttatc tgtcaattcc tttagacgaa aaccgacatc
    40201 tgctttcata ggatctagcg tgtaatcggc accgtatttt tctgctaatt ctctacgctg
    40261 cgctatggga tcgatcccaa cgatggtagt agcacctgct tttttagcta attgaatcgc
    40321 aatttgcccg atagcgccta aaccgaagat tgctacagca tcacctgctc gaacatgtgc
    40381 ttcccggata ccacctaaag cgaattgagc aggatcgtaa catactgcat ttttccattg
    40441 atccaaccga tcaagtttac gtagtttata attatcaaca ccgtttgtaa tcagcgtttc
    40501 acgaatgggt ccataagtgc agactaactc tcctttttga tactctgtca ccaaactgcc
    40561 cgtttcttcg atcgtaccga caatcatatt tcctaattga aattcgccaa ataccacacc
    40621 gcgttggctt ccttcttctc ttggcaagaa taggcgccat tcttctgaaa attcttcatc
    40681 gataaatgga cttaatcctc taaagtcgac aatttctgtt cctggttttg gagtagcgaa
    40741 aattactcgg atacgtactt cgttcttttc gatctcacgg tcttcgtaat ctttgaatcc
    40801 ggctattctt ggttctaatg caactaattt tttcatcttt tctttcctct ttcttttctt
    40861 tttatccttt tacgccgcct tcgactaaat cacctttaat aaatcgttca gataacgcat
    40921 acataatgat gactggtaaa gcggtcacca atgaagcggc catcattcgt ccccaaatgt
    40981 agtctggtgt actgaataat gtgttcaaac cgattggtaa agtaaatttt tcggaggtcg
    41041 acaggaaaat cgaagcaaat aaataatcat tccacgaaac cataaagcaa taaacgaaga
    41101 cagaaatgat tccagaaata gccaatggta taatgatccg aataatgatc tggatccggc
    41161 taagaccatc gatcattgct gcttcttcaa tatcagtcgg aatcgtgtca aaataacttt
    41221 ttagcatgaa tatcgcagta ggaagtgttt gaacgaccat cgtgataatc agtgctgtat
    41281 tggtatcata caaacctaga ccggaaatga ttttaaataa tggaacaacg atcaaaatac
    41341 cggaaaacat ataaacggtg taaaagctag cattgatttt cgagcgagct ttgaagcgta
    41401 gttttgacaa agcgtatgcc ccgctgatcc caatcactac tgcagttacg gaggctatca
    41461 aggagatcac taaactattt ttgaaataca tgatgaatgg aaaaatctca gcattgaaaa
    41521 tatcctgata atgttcaaaa gtccattctt tcggaaaaat agtttgtgtc gttgcaattg
    41581 cttcttgtga atccttgaat gatgtcatca gcatgatcaa aaatggaaac aaattgacag
    41641 ctaatagcaa caaaatcgtc gcgtaaaata agattttcct gctcttttta tttttcattt
    41701 caagtccacc ttctttcgtg agagcaagac gaccgctgca ataatgatga acaatagaat
    41761 cgatatagct gctgcttttc caagatcatt gaacgcaaag gctgtctgat acaaataaac
    41821 gcctaagata ttgactttat tcgtcagtag atagacatct gtaaacatat agaacatcca
    41881 gatagatcgt aaaacaatca cagttgctag tactggtttg attgccggca gtgtcacgat
    41941 cttgaacttc tgccaagcat ttgcaccgtc catttcagct gcttcataaa gcgttttgtc
    42001 gactgtttgc aaaatagcca aaaatgaaat aaacgcatac ggatagtatc tccagatagc
    42061 aaacaaaacg accataaaga agctagcaac tggctggtcg aaccacagcg gtgcttcgtt
    42121 gaaaagctgc aacctatcta ctaacagatc attgacgatt ccataactat tattgaacat
    42181 atatttccaa gcaaaaatca aagaaataga tggcgtaaca taacttaata aaatcagtga
    42241 acgcaccgtt ttcctaaatc tgaacttgcg gttaagcaaa atagctacgg ctaatcctaa
    42301 agctgtactg cctgctacaa ctaagaatgt gtaagcaact gttaaaccta aagaacgata
    42361 aaattcacta tcacttaaaa tttcaagata attgcttaat ccgataaaaa cggcgtctga
    42421 gttaggattc agcggcatat cgaaaaaact gatctgaata ttggaaagca ttggaatcag
    42481 cactaaaaca gctaataaaa gcatgcttgg tgctaaaagt cccatggcta attttaagtc
    42541 agaatgtttc cttggacgat tcattgaaac ctccccctga taatctgcca atagctatct
    42601 acttttttcg aacaccattg gcagaacttc ttgttatttc gtattttttt gtgcgtcagc
    42661 taaagcttga tcgacatctt cgtttccgac agttacttgg ttcactgctt ttccgatcac
    42721 acctgagctt gtgatatctc ccattttcgt gaaattcttt tccccgacta gtccaaagac
    42781 ttgtacttca tcaaaagcac tagcaatctc agatggcagc tcgccaaaag acttgatgac
    42841 ttcattttct ttgtaaccat ccagttcgac tacttgttta ttcactggtt gagcaccacc
    42901 aggagacatc aagacccact tttccatgtt tttcggttga gataagaaag ctgtgaatgc
    42961 ttcagcagcc tctttttgtt tctcgtctag accagaagaa atcgtcaatc cagatactgt
    43021 gccatagaca gcttgatctt tttgtgttgg gatagcaaaa ccgatatttt ctgagttccc
    43081 cgcttcataa acagaaggca aaatgtaagt tgaatagatt gccattggtg ctgttccatt
    43141 catgaaagca tctttgattt ctgtcacatc attagagcct ggcatcgtgt attgggataa
    43201 gttttgataa aacgacaatg cttctctcat cttttccgta tcgatcgtta cctcgccttc
    43261 atcatccaaa acatttgctc catttgacaa agcaaattga gagaacgctt gctcactcat
    43321 tgttccttca gcagtaggca tagcaattcc atattgttta ttctctttat ctgtgaaatg
    43381 ttgagcaatt tttaaaatat catcccaatt ttctggttct gaaaaaccag cttctgataa
    43441 tttttctttg tcataccaaa taccttgaac ccagccgcta attggtgcag caatatagct
    43501 ttttccatct tctgaacgaa caaggttttt ggctccgtca taataattat cttctccagc
    43561 ttcctcgata acgttttgga ctgccgtctg atcaatcagt tcatctttat ccatcacttt
    43621 agcaaaatcc tgactgactt ccattacttc tggtaattta ccggaacgag ctaacgtaac
    43681 gatttttgta ttgaacgctg attcttctac cggcacttgc ttgattttga tgtctggatt
    43741 ttctttttca aaatcagcaa ccagttcatt gatcacactt aatcgttcct gttcgacaga
    43801 agagtgcatg aattgaatcg ttgtctgttg tgattcgtta gagctttgac tttcaccaca
    43861 agcagtaaga agaaatccag tagctagcag acaggtagta acaataattt ttttcatttt
    43921 tttccacctc ttattttatt attttcagcc acatatattc atacggctgg aatatcaact
    43981 ttcgttcttg actgcaatgg ataatttgtc cagaaaacag gtctaggtaa tctccttttg
    44041 gtaaaagata acctgctgat tgattggaaa aattatggat aactaagact ttctcttcct
    44101 tcgcttcgcg aataaaactg ataaaagaat ctgctgagtc cagtaagtaa atcaaactat
    44161 tcggatggaa ggctttttct ttttttcgaa tagatagcat ctgggtcaat tcaccatata
    44221 ctgctgttct taatggatct gtctgcaact ctttctcaat atctgctaac aaaaattttt
    44281 gccgattgat ttttcgattc tctcctgttt tttctacgcc tttgtaatca tttcgacttc
    44341 ccagcacact ttgaatataa attgccggca cgcctggtaa cgttaccaaa aatgaatgag
    44401 cagctaaaaa gcgtttgctt ctccattccg tcgtatctgt tggagaactt aacgcatcta
    44461 gatacgtagc gtttatctca tatggactgg tcgttccatc tgggtttttc ttgtagttta
    44521 ctcgggcacc ctctttcttc agctgttcca ctaattcaag gatcgttttt tccggcagaa
    44581 tacctcgtac cggattcaat ccgataccgt catgggaggc taaaaaatta aaaaaagttg
    44641 tttttttcga tgcgaaatcg atggttttta accattcttt caacttactt gtattacccg
    44701 aacgaatcgc ttgaagggtc aaaggtggta gcgaaaactg atagaccatc tgtgcttcat
    44761 tctcgccatt cccaaaataa ctgatattat ctttgtgtgg cacatttgtc tcagtgatca
    44821 ataccgttcc tggagctgct tcatcagcga ttgcacggaa taattggatg attttatgcg
    44881 tttctggcag gtgtatacaa gaagttccta gttctttcca taaaaatccc acagcgtcca
    44941 agcgaataaa tgaagcgcct ttttctaagt aaaacaaaag aatatcgatc attttcaata
    45001 aaacttctgg atttttaaaa ttcaagtcta cttgatcttc gctaaaagtc gtccatacgt
    45061 gtttttcttt cccgtttttg tcaatgaacg ttgtaagtaa cgggctggtc cttggtctag
    45121 tcacgctgct tgtatctgta tccagtggca aatcaataaa aaaatctttg tacgtatcat
    45181 tcaagtttaa atattcctga aaccaagtac tttcggcaga catatgattg cagacaaagt
    45241 cgaacattaa ccgtgtttcg cttctcattt cttctatatc ttcccatgtg cccaaacggt
    45301 cgttgattgc ctgataattt acaacggaga aaccatcatc agatgtatat gggaaaaatg
    45361 gcaagaaatg tacaactcta aatgtatctg ccaaatactt ttgataaaat ttcttaaatg
    45421 tacgcaaagt tggttgctgc tcttcaaaaa attgatcccc ataagtaatc aagaaaatat
    45481 cttcttcgtc ccaatgcagt ttgcctgcct ggcctttctt ctgctgataa acactgactt
    45541 tttgttcaat catagaggcg gttttctcag acaaatctga gtcgcgataa atcgcttgta
    45601 aaagttttgt atacatcgga ttcccctttc ttttttggga gcgttcccaa cgatttgatc
    45661 atattatgga aaacgcttac tgtcaatagc atttttttaa ataattttga tatacacaaa
    45721 aatacaaata agaaagctta tgtatcaata attaatagct tcttaaaaaa atatggtctc
    45781 tcatgatcat gcaagctatt cctaaatttt caaaatcata gacaaaaaag aatgtctatt
    45841 gtactatgga attattctaa aacgctccca aaaaggaggt gcatataaaa ttgaaaccta
    45901 ctatttatga cattgcgaaa aaagctaatg tctcaaaatc aactgtctcc agagtattaa
    45961 ataaccagcc aaatatctct gataaagcaa aagcaagtgt acttcaagca atcaaagaat
    46021 tgaattatga accgagcaaa attgcaagag gactgtcagg aaatggtttt gacgcgattc
    46081 tagcattatc tcatcgtact tctcatacga cctatggcaa tccttttttt tcagatgtta
    46141 ttcaatccat ttctgccgtt tctgaacaaa ataacttcga cttgattcta caaacggcaa
    46201 aaacaccaga agaagagcta gaaaaatgcg cgaaaaagat ccaagaaaaa atgatccgag
    46261 gaattattat tttaagctct acgatggatg aaacacttct ttttgaattg gatcaataca
    46321 atattcctat tgtggtaatc ggaaaagtcg gaaacgacta cacgaacatc tactcagtgg
    46381 acacggataa tttccaggat agttacgatt tggtggaaac actgatcaag aatggacacc
    46441 gtcatatcgg ctgtctccat gctccgacag aagtttatgt atccaatgat cgtctcaatg
    46501 gttaccgtca atgcttattt gatcaccacc tagatatccg taatgaatgg attatagacg
    46561 gcggctttcg cttagaagat agcatggcag caatgaatga tttaatgaag ctacgagaaa
    46621 gaccaactgc gattttttct accgatgcat taaaatcatt gagtatttac aaagtggcag
    46681 aacaatctgg aaagcagata cctgatgatc tttcgatcgc aggattcagt gatcccttat
    46741 tgtcctccct attttcgcca cagttgactc ggatagacat tccgacaaat cagttaggaa
    46801 tcaaagccac agaactttta ttccaactaa tccaccacca ataccctgaa gaaaaaagaa
    46861 tcattctttc aaccgagatt actctcacag attcgatcca acaacaagaa atgtagaaca
    46921 gaattataaa agaacagaaa cactgaggat aagtcagtta ctctgttctt ttttcaatca
    46981 ctcatccctc gttaccccct cccggtattt tagcgaattt ttcttatttt ccatctgttt
    47041 tagatagctg tggataacta taatgtttgt gttaaactat tttttccaca gggaagaaaa
    47101 aactattttt aaccacgttg tgtataagtt tttatagttc gtttttttaa acacatttac
    47161 ccttatttca atccatgtta tttggggata cttatctcta aaacataaat agaataacag
    47221 acatgtctac tggttttgtt ttattcgagg aattattcaa taatagctag caaaatatta
    47281 aaaataaccg ctctatcttc ccatcaattt attttgcatt caaaaaatga tctatcttta
    47341 cttttgttga ttgacttctc ttggaagatg atcgttccga taccttaatt ggatacgaac
    47401 cgatgttgtt aagatccttt cccacttttc ttctagttag acaaattatt ttagacaaac
    47461 caaaaaagag gttgtgacaa taatttgtca caacctcttt tttaaaatat ctattttgtt
    47521 tgattgttca ttgcgtcttc tgcagccatt tgcgcttcaa tatctgaaat actgtagaca
    47581 ttttcgcttg ctacaccgac ttcttttggt tccatgtcac gataacgttg cataccagta
    47641 ccagctggga tgatcttacc tataataaca ttttctttca aaccaagaag aggatctttc
    47701 ttaccgcgga tcgcagcatc cgtcaagaca cgagttgttt cttggaatga tgcagcagat
    47761 aagaaactat ttgtttctaa tgatgctttt gtgataccta gtaagacagg tcgagaagtt
    47821 gcaggaacgc ctcctgagac tagcgtattg tagttttgat ctttaaagtc tgcgatgtct
    47881 aataatgtac ctggtaagat atctgtatca cctggatcca ttacacgaac tttacgcagc
    47941 atttgacgaa ccattacttc gatatgcttg tcgccgattt ctaccccttg catacggtaa
    48001 acacgttgta cttcacgaag caagtagttt tcaacagata atacatcgcg aacttgcaac
    48061 aattgttttg gatcgattga tccttctgtc aatggtgcac cacggtggat catatcgcct
    48121 tctgctactt tcatacgtgc tgtataagga acagtatacg tacgtgtatc tgtttttcct
    48181 ttgattgtta cttctttggt acgtgttgca ggatcttctg agatatcgat gacatcccct
    48241 gttacttctg tgatcactgc ttgccctttc ggattacgtg cttcaaagat ttcttggaca
    48301 cgaggaagac cttgagtgat atcgtctccg gcaaccccac ctgtatggaa tgtacgcatc
    48361 gtcaactgag taccaggttc accgattgat tgagcggcga tcgtaccaac tgcttctccg
    48421 acttcaacgt cagagccagt tgcaaggttg cgtccgtaac aatgtttgca gacaccatgt
    48481 tttgtattac atgtgaagac agaacggatt gtcactgttt cgacacctgc atcaacgatt
    48541 tgttttgcga tgtcttcgga aatcaattgg tttcctgcaa tgatcaattc atttgtttca
    48601 ggatgacgta cttctttacg ggtgtaacgt cccactaaac gatcttctaa tgattcgatg
    48661 atttcatttc cctcgcggat ggcttggatt tcaagacctc ggtcagtacc gcaatcttct
    48721 tcacggatga ttacatcttg ggccacgtca accagacgac gagtcaagta acctgaatcg
    48781 gcagtcttca aggctgtatc ggtcatccct ttacgagccc cgtgagttga gataaacatt
    48841 tccaagacgg atagtccttc acggaagttc gaaatgattg gcaattccat gattcgacca
    48901 ttaggagcgg ccatcaaacc acgcattccg gcaagctgtg taaagttgga aatgttacca
    48961 cgagctccag aatcagacat catgaagatt ggatttttcg cttccaaacc ttccatcagt
    49021 ttttgttgga tgctgtcttt tgcagcattc caaacagcaa tgacacgttc ataacgttcg
    49081 tcatctgtga tcagaccacg acggaattgt tttgtaatag tttcaacttg tttatgggca
    49141 ttttcaatga tttcttgttt ttcattcagt acactgatgt cagcgatccc tactgtgata
    49201 ccggcatgtg tcgaatgttt gtaccctaag tctttcatac ggtcaagcat cttagaagtt
    49261 tcttttactt tgaatcgttt gaagacttct gcgatgatgt ttcctaagtt tttcttcttg
    49321 aacggtaata ctaattcttg ctctttgata tgtgcaggaa tatcagtacc agcttcaaca
    49381 aagtatttgt ccggtgtttg gacggtcaag ttgaagtctg ttggttcatt cagataaggg
    49441 aattcaggag gcatgatctc gttgaagatg atcttaccaa ctgttgtgat catcgtacgt
    49501 tctttttgcc attcagtaaa tggtttttca cctaatgagt tagggttcac accgatacgt
    49561 gaatgtaaat gaacatatcc gttgcgccat gcgataacgg cttcgttttg atctctgaag
    49621 accattcctt cgccttcgcg tccttcttct tccattgtca agtagtagtt acctagaacc
    49681 atatcttgag aaggagtaac aactggttta ccatctttag ggttcaagat gttttgagca
    49741 gctaacatca acatacgtgc ttctgcttgt gcttcttcat tcaatggaac gtggacagcc
    49801 atttggtctc catcgaaatc ggcattataa gcttcacata caagtggatg caaacggatt
    49861 gcgcgtcctt gtactaaaac tggttcgaat gcttggatac caagtcggtg aagcgtaggt
    49921 gcccggttca gcaatactgg gtgttccttg attacgtctt ctaaaacatc ccatacttcg
    49981 tcttcttgac gttcgatttt acgtttcgca tttttgatgt ttgaagctag ttcgcgttga
    50041 acaagctcac gcatcacgaa tggtttgaat aattcaatgg ccatttcttt tggaagtcca
    50101 cattggtaca tcttcaagaa aggtccaaca acgataacgg aacgacctga gtagtcgaca
    50161 cgtttaccta gcaagttttg acggaaacga ccttgtttcc ctttcaacat atgagaaaga
    50221 gatttcaatg ggcggttacc tggtccagta actggacgtc cgcgacgacc gttatcgatc
    50281 aatgcatcta ctgcttcttg cagcatacgt ttttcatttt gaacgatgat tccaggtgca
    50341 ttcaagtcta acaaacgttt caaacggtta ttacggttga ttacacgacg gtaaagatca
    50401 ttcaagtcac ttgttgcaaa acgtccacct tctaattgaa ccattgggcg taaatctggt
    50461 ggaataacag ggataacgtc cataaccatc cagcttggtt gatttcctga agcgcggaat
    50521 gcttctaaaa tatccaaacg gcggattgca cgtgtacgtt tttgtccttg tgcagatttc
    50581 aattcttctt tcaattcggc tgcttctgca tctagatcaa cattatcaag taattgttta
    50641 atcgcttctg cacccatagc agcttggaat tcttgtccat attgttcacg tttttcgcga
    50701 tattcgcgtt ctgtcaacaa ttgttttttc tctaaattcg tatttcctgg ttcgatgact
    50761 acatatgaag caaaataaat gatttcttcc aaagcgcgtg ggctcatgtc taatacaaga
    50821 cccatacgtg aaggaatccc tttaaagtac cagatatgtg aaacaggagc tgctaattca
    50881 atatgtccca tgcgttcacg gcgaactttc gaacgagtaa cttccactcc gcatcgatca
    50941 caaacgattc ctttataacg gatacgtttg tattttccgc aggcacattc ccagtctttt
    51001 gtaggaccaa aaatccgctc acagaacaac ccttcgcgtt caggttttaa ggtacgatag
    51061 ttaatcgtct caggtttttt tacttcaccg taagaccagc ttctgatttt ttcgggagaa
    51121 gccaaaccta tttgcatact ttcgaattta tttacatcga tcaaaagggg ttccctccat
    51181 ttcatttaat ggcaaaccgc aagacggctg atcttcgacc gccttgcagc tcatagaccg
    51241 gattagtcta aattatcttc tgcggtttca aagttttgga tgacatcgtc tttttcatct
    51301 tccacttgtt cagcagcttt cttttctaat tctttggcag tttgctgttc ggcaaatttt
    51361 gtcaaagcat caacagtgat caaatcgtcg tcttcatcgt ccatgtcgcg aagttcgatc
    51421 tctgtttctt cgatatccaa gacacgcatg tccagaccta gtgattgcaa ttctttcacc
    51481 aatacgcgga atgattccgg tacacctggt tttggaattg gttcaccctt gacgattgct
    51541 tcgtatgttt tcacacgtcc gactacgtca tctgatttgt atgtcaagat ttcttgtaaa
    51601 gtataagccg caccgtaagc ttccagtgcc catacttcca tttcaccaaa acgttgtcca
    51661 ccaaattgag ctttacctcc caatggttgt tgtgtaacca atgagtaagg tccgattgaa
    51721 cgtgcatgca atttgtcatc gaccatgtga gcaagtttga tcatgtacat cacaccgaca
    51781 gacacacgtc catcaaatgg ttcacctgta cgtccgtcgt acagaacagt tttcgcatcg
    51841 ctggccatac cggcttcacg aactgtttcc catacgtctt catcacttgc accatcaaat
    51901 actggcgttg ctacgtggat acctaactga cgtgcagcca tacccaagtg taattccaat
    51961 acttgcccga tgttcatacg tgaaggcacc cctaaaggat tcagcatgat atcgattggt
    52021 gttccatcag gtaggaatgg catatcttct tccggcataa tacgggatac aaccccttta
    52081 tttccgtgac gaccggccat tttatcccct tcatggattt tacgtttttg aacgatataa
    52141 acacgaacta acatgtttac gcctggtgac aattcatctc cagcttcacg agtaaagatt
    52201 ttcacatcgt gaacgatacc gccgccgcca tgtggtacac gtaatgatgt atcgcggact
    52261 tcacgagctt tttcgccaaa gatcgcatgc aatagacgtt cttctgcaga taattctgtt
    52321 accccttttg gcgtgacttt ccctacaagc aaatcgccat cttggacttc tgcaccaata
    52381 cggatgatac ccatttcgtc taaatctttt aatgcgtctt ccccgacatt agggatttcg
    52441 cgtgtgattt cttcaggtcc taattttgta tcgcgggctt ctgattcata ttcttcaata
    52501 tggatagaag tgtatacgtc atcttttacc aaacgacggc tcatgatgat cgcatcttca
    52561 tagttgtacc cttcccaagt catgaaacca actaaaacgt tttggcctag agccatttcg
    52621 ccttgttcca tagatggtcc gtctgccaga gtatcccctt tttcgacttt ctcacccaaa
    52681 tgaacgattg gacgttggtt gtagcttgtt ccggagtttg aacgacggaa ttttgttaca
    52741 tcgtatttat ctaatgcacc gttgtcgcgg cgtacgcgga tttcagaagc atcaacgtat
    52801 tcaacgacac catcatgttt acataacaaa gcagctcctg agtcatgcgc tgatttgtat
    52861 tccataccag taccaaccca tggtgcttga ggattgatca acggcactgc ttgacgctgc
    52921 atgttggcac ccatcaaggc acggttggag tcatcgtttt ccaagaaagg aatacatgct
    52981 gtcgcaacgg caactacttg tttaggtgat acgtccatgt agtctacttt atcaatagat
    53041 acttctaagt tttcactttg agcacgagcc ataacaacgt cttgagcaaa tgttccatct
    53101 tcattcaatg ggctgtttgc ttgggctacg atgtaatggt cttcgatatc agctgtcaag
    53161 tagtcgattt ggtcagtaac acgacctgtt tcacggtcta cacgacgata aggtgtttcg
    53221 ataaatccga atttatttac tttcgcataa ctggacaaac tattgatcaa cccgatgttt
    53281 gggccttcag gagtttcgat cggacacata cggccatagt gggagtagtg aacgtcacga
    53341 acttcataac cggcgcggtc acgagtcaat ccgccaggtc ctaaggcgaa aagacgacgt
    53401 ttgtgtgtca attcgccaag agggtttgtt tgatccatga actgtgacaa ctgagaagaa
    53461 ccaaagaatt ctttgatact tgccacaact ggacggatat tgatcaattg ttgaggtgtc
    53521 aatgtttcag tatcttggat cgacattctt tcacgaacca cacgttccat acgtgctagc
    53581 ccgatacgga attggttttg taaaagttca ccgactgaac ggatacgacg atttcctaag
    53641 tggtcgatat catcgacatt gccgatacct tccatcaagt tcaagaaata gctcattgaa
    53701 gcaatgatgt cggctggacg aaccgttttt acagctgctt ctggatagcc gtttccgatc
    53761 acgtttactt cacgttcagg gtctcttggt gaaaatactt tgatgacttg gacagtcatt
    53821 ggatctgtga ccacaccgtc ttctgatgga tagtaagtca ctgaatttag gccattatca
    53881 atgaaaggag ctagtgtttc catgacttgg tgagtcagaa ctgttccttt ttcaacgatg
    53941 atctcgcctg tttctggatc aactaatgtt tcagctaatg tcagattcaa tagacgtgtt
    54001 ttcaaatcta attttttgtt tactttgtaa cgaccaacgt ttgctaagtc gtaacgtttt
    54061 ggatcgaaga aacgagcatt cagcaagtta cgtgagctgt ctgctgtttt tggttcgcct
    54121 ggacgcaaac gttcgtaaac gtctttcaaa ccttcttctg ttcttgagtc gcttgcgttt
    54181 ttatgcaagt ctttttcgac tgtattgcgt aatgtttcgc tgtcgccgaa gatttcaaag
    54241 atcgtatcat cggaaccaaa tcctaacgca cgaactaata cggttaaagg aatcttacgt
    54301 gtacggtcga tacgtacata agagatgtct tttgcatcag tttccatttc tagccaagct
    54361 ccacggttag ggataacagt agaaccgaat ccttcttttc cgtttttgtc gacttttcca
    54421 tggaaataga cacctggtga acggactaac tgagaaacga ttactcgctc tgccccgttg
    54481 atgatgaatg ttccttgttc tgtcattaat gggaaatcac cgaagaatac ttcttgtgct
    54541 ttgatttcgc cagtctcgcg gtttgtcaaa cgcaatgtta catgtaatgg tgcagagtag
    54601 tttgcatcat gcgcacgagc ttctgctact gtatactttg gttctttcaa ttcataatct
    54661 acaaattcca aagatagatt gccattgaag tcatcgattg gcaaaatgtc ttcaaacatt
    54721 tctctaagtc cctcatctaa gaaccattgg taagagtctg tttgaatttc gatcaaattt
    54781 ggtaattcca acacttcact gattcttgcg aaacttctac gttcgcgatg ttttccgtat
    54841 tttactacgt gtccagccaa gctcttcacc cctctaaaat gtcattcaaa aagactaccc
    54901 gatcaattgt tacaataata tttcaaatat tatttttagg taacaacaga cattttttgc
    54961 ggcttttagg caaaaaaaaa ccaaaaatag aacattctct tgaaacctta cttcgtgagc
    55021 ttctactttt gtttccttat attaaagccg aaacggacaa tatttcgttt ctgccttttc
    55081 ttcatcagat agtttttgca acttcatata ctacacttat tttctataaa agtcaacact
    55141 tcctggcgtt tcttctgctt tttcgcaaca ttttcttaat gttttcaatt ttatgttttc
    55201 aattatctga caattcttaa ttgacagacc tttttatctc ggttatactt tagaaaattc
    55261 attttgtgga ggaacttcta tgcgaaccaa catcaaccaa atcgcaccaa cacaactgaa
    55321 taacttttac tttagctact ttagataggt ttgtattcat catgatggat acaaacgtta
    55381 aacgacagtt tgtatctatg atggctaaag aactttgtat tgcagcaaaa agccacgtag
    55441 acaaaatgct aagtggctga gcagtgaaaa tacaaagtaa aagtatcaag cattctactt
    55501 tttcaattta ttttccgact tttcaatcca tttggacatt ttgtctgaat ggattttttg
    55561 tttcccaaaa ttaaggagga aaaagaaatg aaaaaaaata taatcatcgg attaggcgct
    55621 gccctgctac tagctttagg aggttgcgca caaaaagaca attccgcaga ggcatcagat
    55681 ggacaaaaaa caattggcgt attgcaactt gtacaacata actcgttaga tgctgcctat
    55741 aaaggattca aagaaggatt agcagaagaa gggtataaag aaggcgataa tctaacaatc
    55801 gattatcaaa atgcccaaaa caatcaagac aacctgaaaa gtatgagtga gaaactcgtc
    55861 aaagaagatc ctgatttgct acttggaatc gccactccag cagcacaatc tttattaaat
    55921 gaaacaacca ctatcccgat gactgtcaca gcggtcacag acttggaaca agcccattta
    55981 gtcacatcca atgaaaaacc tggcggcaat gtgactggca cgacagatat ggtgccaatc
    56041 gaaaaacaaa tcggcttact gttaaatatc gtgccagacg ccaaaacaat cggcatcatg
    56101 tataacaacg gtgaagcaaa ctctaagatc caagctgatt tggcagaaaa agaattgaaa
    56161 aaagcgggcg tcaaagtcaa agtactgaca gcaaattcca caaatgatgt ccaacaagtg
    56221 acgaaaagtc tagctaaaga tgtagatgga atctatattc ctactgataa cacgttcgca
    56281 agtgcggcaa gtgttgtcgg tgaagtcgca aaagaaacaa aaacacctgt cgttgctggc
    56341 gcagttgatc aagtcaaaga cggcggtcta gcaacagtag gaatcgacta cgaaagcttg
    56401 ggcaaacaaa cagggatcat ggcagcaaaa atcttagacg gcaagaatcc aagtgaactt
    56461 cctgtcgaaa cagcgaatga tttggaactg tatgtcaata aagacatggc caaagcatta
    56521 ggcatcaatc cagacagcat caaagaagct gaataaaaca caggaggatt ctcatgacaa
    56581 atttgctctc tcttttctta tcatctgcat cgcaaggggt cttatgggcc ctacttgcga
    56641 ttggtgtata cgtcactttc cgtatcttgg acattgccga cttgactgct gaaggaagct
    56701 ttcctttagg tgcagggatc gcggcagtaa gtattacaaa tggctatcat ccattgacag
    56761 cttgtcttct aggcttttta gggagtgcgg cagcagggct tgtttccgga ctgcttcaca
    56821 caaaattgaa aattcccgcc cttcttgcag ggatcatcac catgactggt ttatattctg
    56881 tcacatcccg tgtgatgggt gcgccgaaca tctctttatt gggtcagcca acgatctttc
    56941 attgggtcga gtcattcggc ataacaaaag acaacgctgt actgatcgtc ggtctgcttt
    57001 ttgctttgat cgttgtatgt ttacttgttt tgttcttacg tacagaaaca ggacttgcta
    57061 ttcgtgcaac tggcgataat ctggcaatga gcgaagcaaa cgggatcaac acagataata
    57121 tgaagatcat cggttatatg atttctaatg gatgcattgc tctttctggc tccttgcttg
    57181 cgcaaaacaa cggctttgct gatttaaatt ctggtattgg aacgatcgta attggacttg
    57241 cttctattat catcgcagaa gttttgttac gtaaccagcc actatttctc cgtctcttga
    57301 ctgtcgtttt aggtgcggtc atttatcgtt ttattttagc gttagtcttc gaactgaatg
    57361 ttgaaccaag tgattcgaaa cttgcttctg ctttcgtgct agtgatctgt ctttctttcc
    57421 cgcagatcca gcaaaaattc catttacctc aaaaaaagaa aggcggtagt gtcaaatgaa
    57481 tgacgtctta acattggaaa atctccatca tacctttgaa aaaggaacga tcaacgaaaa
    57541 tcatgtcctg aaaggcatta atctttcctt agatcccggc gacttcgtga cgatcatcgg
    57601 tggaaatggg gctggtaaat ctactttgct gaacagcatc gccggtacat tttctgtcga
    57661 tcagggtcaa attttattga atggaaaaaa tatcacgaaa aaatctgttg tcgaacgttc
    57721 gaaatccatc agtcgcgtat tccaagatcc taaactaggg acagccgttc gtttaacggt
    57781 agaagaaaat cttgctcttg ctatgaaacg aggaaaaaaa cgcggcttct tccgtggtgt
    57841 caaaccacaa gaccgaacat ttttcaaaga ccagctggtt cggctaaatt tggggttgga
    57901 aaatcgttta tcctcagaaa tcggtttgct gtctggagga caacgtcaag ctattacgtt
    57961 attgatggcc acattacagc gtccagaact gatcttatta gatgaacaca ctgcagcgct
    58021 tgaccctgct acttccaaaa cggtgatgga attgacagaa aagctgatca ctgagcagaa
    58081 tctcactgct tttatggtca ctcatgacat ggaagacgcg atccgctatg ggagtcgact
    58141 gatcatgctg catcaaggaa ggatcgtcgt agatatccag caagaggaaa aacagcagct
    58201 cacagtgccc caattattag cgttgttcaa acaaaacagc ggcacggcat taaaagacga
    58261 tcaagtactt ttatcttcat aatcagaaag aggatgggac aaaaaatgaa cgcccaccct
    58321 cttctttttt ctctttcctt ctttcgtttt tgctttatgt atcaaccgtt gtttcttcga
    58381 aaactatttt gttctctcct tcttcctgat agaatggatg ggaaaggagc ttgatgccat
    58441 gacaacgaaa gacaaggtac ttcaattatt gaaaaagaca ccagattttc tttccggaga
    58501 aaagttggca cagcaactgg aagtttcccg gacaagtatt tggaaagcca tcaaagaatt
    58561 ggaaaaggca ggctatcgtt ttgagcacgg gcctacaggg tatcgttacc tgccctctga
    58621 cgtactagat gcaaaagaaa tccagcaaga gctacggtcg tttattcctg atttgaaagt
    58681 acaaacgatg atgacttctg aatctacgat gaaagatgcc aaactggcag cagctcaagg
    58741 agattctgtt tcgaagttat ttgttgctga tacacaagaa caagctcgtg gacgttttgg
    58801 acggcctttt ttcgctgaac ctggacgagg aatctacatg agtctcttgc tccatccaga
    58861 caaacggttt gatgaattgc ctcaatatac gatcatcgca gccagtgcct gtgtgaaagc
    58921 cattgaatct gtaaccggtc gttctgcttc gatcaaatgg gtcaatgata tctacatgga
    58981 tggaaaaaaa gtctgtggga ttttatctga agcagtcagt gatatggaaa gcggcaggat
    59041 cagtcatatc atcattggga tcgggcttaa tttttctgtt cctcaaaatc attttccagc
    59101 tgatctccaa gaaaaagcca tctctgtctt tcccgacgga caagctagtg tcacaaggaa
    59161 tcagctaatc agcaaaatct ggcaagaatt gttcacttat ctttctcacc cagaaaaagc
    59221 gttggacttc tataaagaaa aatcattcgt attgggaaaa accgtgtcgt tcaatcaaaa
    59281 aggaacgact tatgtcggtc ttgcaaaaga aatcggtgat catggcgaac tgatcgtcca
    59341 aacaaatgaa cagaagatga gtttgtcttc tggcgaaatc agtctcacat ctatccgtac
    59401 gcaataatta tcagatttca caaaaggaca cctgatctca tacagtgtcc ttttttctga
    59461 attctcttca aaagactctc cttattctat cagctgacag tttctctatc ctctagaaaa
    59521 aggtattcta aaaatatcta taaagcatgg tacactttct ttaaatgaat caatgcaaaa
    59581 aacaagagag tcatcagttt acacgatcaa aagagatagc aggccgcttc ctttttcaat
    59641 cttatagata gaccatgggt aacgataaaa acaaaaaaga acttgcgact tattttgccg
    59701 taagttcttt tttagctagt gccttaatct cttaatccca acaaacgtct cgcatagatc
    59761 acctgaccag agtgcatagc agcatcatca ataatagaaa cgagacgcat tcctcgtgtg
    59821 actggtggtg tccagttctc gtcaattact tcatctagct cggaaggttc cagccttctt
    59881 aagtaagaaa tagcaaaatc agcagctcct cgcaagtatc ctagcagatc ttctatttga
    59941 ttagcttgga tctgctttgc ttgttccaga ctatgcttcc aatcttgttc gttatctgct
    60001 atcgtcatcg gaaaccggct ttcccagtct tgactatgcc aaattggaga agttcctgct
    60061 aaatcagcaa tctggaaatc taattctcga gcggtatgcc aagccagcca agtcattgat
    60121 ttgatctgcg gggctctatc ttccactgga aaacgattgg cctcctcaat agagacgcct
    60181 tcaaacaaac gttcaaaccg atcgtatgcc cgatccacac tctcgcatag catatctaaa
    60241 taatccattt attttcctcc tttttattta tcctacttac tttttcctaa ttctaggata
    60301 cctacttata tgttactaca cacccttatt ttttacactt taacagtcac catcatcaat
    60361 agtttggaga ttgaaagaaa aagatagtgt cgaactatca attgaacaag aagcaacaat
    60421 atgaacgttt cattaatatt ctttaaataa acaatgattt ttcaaacgaa cagtttaaga
    60481 ctaggagaaa aagagtataa taggaaaatg tttgaaagga aaggaagggg aaaaatgaaa
    60541 aaaagggcaa gtttactagt cctagttgct ttgttgttca atatcttttc gtatggtgtg
    60601 gccgtttcag cggaaacata cattcctaaa gaccctggga atatttataa tgatctaact
    60661 ggtaactatg gcttgttagg aattgctagt caattccacg tatttgctaa aaataagaca
    60721 actgtgaatg cacatacaga cggaaatata gcaacacatg aacttgatgc aaaaaataat
    60781 tttggtacag agcttcatga aggtttattg aaccaagaaa taaattatat acaaaaaact
    60841 gattctttcg ctaattcttc aggcatacct acaggtagca caagaatgaa taaatttgtc
    60901 gttggcagta acgtggatgt agcacttcaa gatggtcatc ctacagtcaa tggatccagg
    60961 cttgatcact taactccaga tgatttttat aaagatcgtg ctgggcatga atatattgat
    61021 ttcgagcagg aatttgctaa attgaatgta gcagcaaatg atcttgcaac gatcactcca
    61081 gctaaaacat atactgctgc agattttcca gacatgaaca atcggacaat cgatttaact
    61141 gatttatcag ataccgggtt tttattggta aatatcgatg cagaagtgtt aacgatgaat
    61201 acgccacttc aaatcattaa tccaaatgat caagtagttg tatttaatgt catcaacagt
    61261 tcttctgcat tgaacgtaca gtcaccaatc aaatacaatg atcgttcaaa tcatgaaaca
    61321 gaagattttt cggatgcgaa tatctcttgg aattttggaa atgagatgac tgatttgaca
    61381 atcagtgctc cttttcaagg aacaatcctt gcgcctaatg ctactatccg cattactcaa
    61441 aaccaagacg gaacgattat aggaacaaat gtgattttag atgcagctac caatcgttgg
    61501 gatcctaacg aaatatttat cagcgacaat ggtacagata cgacagacac aagcgacagt
    61561 acagatacat ctaccacaag tgatagctca gattcatcaa cttcaagcga cagtacagat
    61621 actacctcta ccacaagtga tagcacggat acatcagctt caagcgacag tacagatact
    61681 acctctacca caagtgatag cacggacaca tcagcttcaa gtgacagtac agatactacc
    61741 tctaccacaa gtgacagcac ggacacgtca gcttcaagcg acagtacaga tactacctct
    61801 accacaagtg atagcacgga cacatcagct tcaagtgaca gtacagatac tacctctacc
    61861 acaagtgata gcacggacac gtcagcttca agtgacagta cagatactac ctctaccaca
    61921 agtgatagct cagattcatc taccactaca agtgatagca cggacacgtc agcttcaagt
    61981 gacagtacag atacatcctc taccacaagt gatagctcag attcatcaac ttcaagcgat
    62041 agtacagaca cgtcgtctac cacaagcgat acacgtcatg caagtgtctc cttctcaaaa
    62101 acaagttcgg ataacaggac gaactttaac ttaactaata aaacaagcaa tgacaatgga
    62161 aacaaatcaa aaagagcact tcctaaaact ggaagtcaat cgaataattg gataacactc
    62221 gcaggcgtta tattacttgt aatcggttta agaatcactt ttatgagtta taagaaatcg
    62281 aaaaggtaaa aaaatattca agataaaaaa gagcaacgtc gctaacggac gttgctcttt
    62341 atttttgctt tttatcataa atacaagaac tacaattcaa tttgtcaaaa aacacgtaga
    62401 tttccttctg agaaatttat ttacgtatcg aacctttccc tattcagtct ttgcgatcca
    62461 aaatcagttg ggtaagggaa aagagattct cttttgttcg aagagaggtg gcaggtaatt
    62521 tctttatttc cttcaaagcc ttttctgtgt aagaggccgc taacttccta gcttcttcca
    62581 cgcctcctgt atgttcaacg attttgcgta cggcgtcgac atcttcttct gtcattgccg
    62641 ctttcttctc taaataaggt agtagctttg gtttgttttt ttgcaaagag tagatcaacg
    62701 gtaaagaata gaccccttga cgcatgtctt ctagtacagg tttgccgatt tcctggctct
    62761 cttttgtata atctaaaata tcatcgataa tctgaaaggc catcccgata gaaagtccga
    62821 tatctcctgc tttttttgcg aagcgctcgc ttgttccact ttcaaaagcg ccaacagaac
    62881 aacttaattg gaacagttca gctgtcttac ctgaaatatt ttccaaatat tcttttacag
    62941 aaagttcata attatagcga tcatccatct gccctaattc gccattcaat actttttcca
    63001 tactgcgaga attcaattgg agacttttca aggaagtgga gtaatcagac aatagtttaa
    63061 aacagcagac aaataaatag tctcctgcat agacagaaac gacattacca aactgactac
    63121 ggatattagg ctgaccacgt cgcagatccg cttcatcaac gatatcatca tggatcagtg
    63181 tggccgtatg gagcatttcg atagaagctg ccaaagcgat ggctttgtct cgatcttgct
    63241 ctggtccaaa ttgtgagaac aatagctgat aggcaggacg caacagcttt ccgccggcat
    63301 ggatcgtttc tttgattgct tgttcgacag gtttgttttt caggcggaca gtttcttcca
    63361 tccgttttag tgtttctgtc aattctttac ttaaagcagg atagttttcc cacattggat
    63421 gtagcttcat aaaaaaactc cttgtgtgac gattattttt tggtaaacat tgggctccat
    63481 ttttgtttgg ttccctgctc ataatctttt tggaatcgtt gaagtgtctg cacatgtcgt
    63541 aaaagataat tcgctgcgat cccgattgca atccctgata aaatccctaa aactgaaagg
    63601 actggcaagt acaacatgac tgtccatgat tgtgcaatga aagaagccat caaaagctgt
    63661 ccgacattat gcatgaaacc gccggccgca ctaattccga tgatactgac acgttttggt
    63721 cctaattgct tgaccaataa cattccaaaa taactaagca aagcaccact catactataa
    63781 aggaatgtgg aaatcgttcc gcctagcaaa gtagtcagga atagtcgtag ccaaagtagt
    63841 aagaagctgt cttgtttttt catggtaaaa atggcaacga tcgtgattag attggctaag
    63901 cctagttttg caccaggcgc aaaagaaaaa ggataaggga tcatattttc caataaacca
    63961 atgatcactc cttgtgcaac aagtagcgaa atataaatca ttttttgtaa tttactcatg
    64021 gtgtgtaaag gtctaataaa tcagactgtc ttcgtcacct ccatctgttg aacggacttc
    64081 gatcactaat ttatgtggca aacagacgat ggtttcgcca tttttcgttg cccagcctcg
    64141 acgtacgcag atctggtcat cgcaatctgc ttcttttatc cgtactcgat cgccatctat
    64201 ctcgatcaag ttataatctc cgtgttcatc tttgtaagta tatgtgttgc tctcttctcc
    64261 agccatcaaa gggaatgttt tgatttctgt gccatccaca cgcagtaccg cttctttttc
    64321 tgctgttgcg gtgttttgct gaagaccaaa aatcatgact ggtaaaaaag aaagaacagt
    64381 caaaagcaaa ataataaaaa catcccaagg tttgagcaga cttttttcag caaattcttt
    64441 aaggctcatt tttgttctcc tttttccaga ttaactcacc caattttagc ataaaaacaa
    64501 gaggttgtga cacctgtgtc ttgctttgag taataagaac gaagaataga aaacagcttt
    64561 ccatgttttc taattctttg ggcttattac cgagaagcag caggtggaac accgtttata
    64621 acaagaggtt gtgacagaag tgggcaactt caagaaataa gaaggaattt acgaaaatta
    64681 cttttcaagt ttttgtgaaa tttcggctta tttttcgaag aagctacttc tggaacaccg
    64741 tttataacaa gaggttgtaa cagaggttgt gacacctgtg tcttgctcat ggaggcttat
    64801 ctcgggcatc ttattccttt aattttacat aaaaaggagg ctgtgacggt ttgtctcagc
    64861 ccctttctat tgaaatcttg cattcaaata acgttcttta tctatttatt tcttgccgta
    64921 ctgggaactt ggtctaccgt accaccaatt acctagtgta cgttgtagcc atggaattac
    64981 ccagcgatcc aacccaatcg cacgtccgga accgttcatc aatgcgaaag caacaaaaat
    65041 gaaccaaatg tttacccagt aaaacatgcc tgataagcag aacgtgatca ccaatacaat
    65101 cgttgtcgca ctgcatagcc atgtgaataa tccagcaatc aatgctaatg ccaaggcaat
    65161 ttcaaagaat accatgaatt tttggaagaa cattgctaca tcattgtttg gcatgatcac
    65221 ttgcatgatc tttgtgaacc agtctggtga cttctcaatc acagccattg gttcttcacc
    65281 gtatgcataa ctcaaaccaa aatgtgcagc ttgagtcgct gcttctccgg cacttgcccc
    65341 tgctccgctg gcagctgtgg ttgcatcacc agcagcagaa gcaccactgg caacatctgt
    65401 tacattgtat tcccatgtcc aagggaacac actttttcca gtgaaccatg atccttcacc
    65461 aaaccaagta cttggtttga acacttcacc attcccaatg atttttttgg aagcttcaac
    65521 gaaccaaact aaaccataga aaatacgaag tggcacactc cataagacat tgccgtaacg
    65581 agaagaatgt cctcgagtca cgttgcgatc atctttgata tggaaaaact catgcattaa
    65641 atattggaac atataataac cagaacgaat atcaaagaag tatttcaaat tcacgatatg
    65701 tttcattacg atagctaaaa atccgcttaa atggatctta tcaaataggt tagctacccc
    65761 ccatttggca ccaatagaaa ccataaatcc ttgatagttt cctttaaatt tatgcttttc
    65821 tccgcctttg atcgaagcca cgatattcgc tgcggctgtg tgtcctgttt gttcagcagc
    65881 ttgaacgatc tgcggtgtcg gtgttcctgg gaattcttca taaaagacta aatcaccaat
    65941 gatatagatg tttttatctt cgtagccttt tgcctgcata tattcattgg cgatcaaccg
    66001 ctgtccgcgt gctgattcta atccaaagtc agcagcgtca gaagttcctt tgacaccagc
    66061 tgtccaaatc agtgtgtgag tcggaatgtt gcgtccgtct ttcaatttga tatgatcagc
    66121 agccacttct acgattggtg cattcaataa taattccacg ttgtgcttac gcaaatagcg
    66181 ttcagctttt gcagcatcat ttcgatccaa catattcaag atcgtcggca ttgcctctac
    66241 gaccatcagt gtgatttcgt ttggatctaa tttataatct ttggctaggc gatttttcca
    66301 gtcgatcagt tccccaatca tttcaatacc ggtaaatcca gaaccacaga caacgaaagt
    66361 cagcatggct ttacgcagtt catcatctgg ttccaatgca gcttttgcta ctgtcttctc
    66421 aatatgttcc cgaatcctta cagaatcttc aaatgaccaa agggtgaatc cgtgtgcttt
    66481 gacaccaggt gtaccaaagt cattcggctc tccgcccatt ccaaggatca gctgatcaaa
    66541 aggataggaa cctaatttgg tcttgacgat ttttcgttct ttatcgatac cgattacagt
    66601 gtctgtgaca agttgtacat tcttttgacg agcaaacaaa tgctgcagat cgtattggat
    66661 tgcttctggt tctacacgtc cgccagctac ttcatgcaac tcggtcatca tagtatggta
    66721 cgaatgacga tcgatcagag taattgctac atcttctttt ttcagtttct ttgccaagta
    66781 ttttgtagct gaaacaccgg catatcctgc tcctacaacg acaatatttt gctttgccat
    66841 tgatcatccg ctccttatag actatctata taatgaatat atgataattc ttttagtttg
    66901 atacttatta cacaatctcc atatattata tagatgttct gttcttttgt ctaactcctt
    66961 ttggattttt ttcaaatttt aaaataaagc gttttttcac gaaatttgct gaaagaaaac
    67021 gtttgaaata ttacatgggt tatttatcaa aaatagttga cttataggct aaaaagatta
    67081 gaatgtataa tgaatcacaa agaaaaattg tggactagaa atggaatggt ggggtattaa
    67141 aatgaagaaa aaacgttttg taactggatt tgccgtatta gcattttcag ctctagtgtt
    67201 aggcgcttgc ggcgcagatg acaacggaag ctcaaactct tcttctgaat catctacagc
    67261 acaatcttcg actgcaaaaa gcacaacaga atcatctgca aaagttgtag ctggcggaga
    67321 tttgcaagac ggcacatata aattagaaga aaaaaattat tcaaatggtt accgtgcagt
    67381 ctttgaaatg gttgtaaaag acggcaaaat cactgaatca aaatatgata acgtcaatga
    67441 aaacggcgaa tcaaaaacaa aagatgcaga atacaacaaa aacatggaag caaaatctgg
    67501 cacaaaccca gaaaaataca ttcctgagtt gaatgaccaa ttcttaaaag cacaaagcgc
    67561 aagcggtgtg gaagtcgtaa ctggagctac tcactcatct gaaagcttcc aaaactacgc
    67621 acaacaattg atccaagctg ctcaagctgg taacacagat acaatcgaaa tcgacaatgg
    67681 tgctgatttg aaagacggca cttacaagct tgaagaaaag aactactcta acggctaccg
    67741 tgtgcaattc gaaatgacag ttgctggcgg caaagtaact gaatcaaact ttgattatat
    67801 cgacaaagac ggtaaatcaa aacaagatga tacagaatat aatgaaaata tgaaagcaaa
    67861 aagcggtaca gaaccaaaaa cttacatccc tactctgaac gacgaattcg tcaaagcaat
    67921 gggcgaagaa gatggctcac ctgctaatgt agaagttgtt acaggtgcta cacacagctc
    67981 acattcattc atcatgtacg cacaacaatt agtgaatgca gctgaaaaag gcgacactca
    68041 aacaatcgaa gtagataata tcgtaacaga aaaataatca cataatcata ctaataaaag
    68101 ttggagggtg ggacgatagc cagattaggc agtcgtctca cctttcaaaa tgaagagagg
    68161 aaaaagatgc ggaaaaaact actattttcc ttaatcacac tgggcatctc tt
//
LOCUS       DAFENC010000011        65448 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.011, whole genome shotgun sequence.
ACCESSION   DAFENC010000011
VERSION     DAFENC010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 65448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65448
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.011"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            130..993
                     /locus_tag="LP493_000942"
     CDS             130..993
                     /locus_tag="LP493_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBL2133106.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1122..2744)
                     /locus_tag="LP493_000943"
     CDS             complement(1122..2744)
                     /locus_tag="LP493_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2133107.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            2993..3514
                     /locus_tag="LP493_000944"
     CDS             2993..3514
                     /locus_tag="LP493_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBL2133108.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(3700..5430)
                     /gene="spxB"
                     /locus_tag="LP493_000945"
     CDS             complement(3700..5430)
                     /gene="spxB"
                     /locus_tag="LP493_000945"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HBL2133109.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5595..6413
                     /locus_tag="LP493_000946"
     CDS             5595..6413
                     /locus_tag="LP493_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HBL2133110.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKHHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6516..6713)
                     /locus_tag="LP493_000947"
     CDS             complement(6516..6713)
                     /locus_tag="LP493_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133111.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            6882..7460
                     /locus_tag="LP493_000948"
     CDS             6882..7460
                     /locus_tag="LP493_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBL2133112.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            7555..7692
                     /locus_tag="LP493_000949"
     CDS             7555..7692
                     /locus_tag="LP493_000949"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133113.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(8505..9008)
                     /locus_tag="LP493_000950"
     CDS             complement(8505..9008)
                     /locus_tag="LP493_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBL2133114.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            9367..10392
                     /locus_tag="LP493_000951"
     CDS             9367..10392
                     /locus_tag="LP493_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBL2133115.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            10715..11593
                     /locus_tag="LP493_000952"
     CDS             10715..11593
                     /locus_tag="LP493_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
                     /protein_id="HBL2133116.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            12069..12185
                     /locus_tag="LP493_000953"
     CDS             12069..12185
                     /locus_tag="LP493_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBL2133117.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            13113..13451
                     /locus_tag="LP493_000954"
     CDS             13113..13451
                     /locus_tag="LP493_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133118.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            13545..13775
                     /locus_tag="LP493_000955"
     CDS             13545..13775
                     /locus_tag="LP493_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133119.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            14175..14546
                     /locus_tag="LP493_000956"
     CDS             14175..14546
                     /locus_tag="LP493_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HBL2133120.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(14820..15512)
                     /locus_tag="LP493_000957"
     CDS             complement(14820..15512)
                     /locus_tag="LP493_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBL2133121.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(15515..16300)
                     /locus_tag="LP493_000958"
     CDS             complement(15515..16300)
                     /locus_tag="LP493_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL2133122.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            16537..17937
                     /gene="lacG"
                     /locus_tag="LP493_000959"
     CDS             16537..17937
                     /gene="lacG"
                     /locus_tag="LP493_000959"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HBL2133123.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            17962..18279
                     /locus_tag="LP493_000960"
     CDS             17962..18279
                     /locus_tag="LP493_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBL2133124.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            18292..19965
                     /locus_tag="LP493_000961"
     CDS             18292..19965
                     /locus_tag="LP493_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HBL2133125.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            19979..21610
                     /locus_tag="LP493_000962"
     CDS             19979..21610
                     /locus_tag="LP493_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HBL2133126.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(22101..23666)
                     /gene="guaA"
                     /locus_tag="LP493_000963"
     CDS             complement(22101..23666)
                     /gene="guaA"
                     /locus_tag="LP493_000963"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBL2133127.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(23725..24648)
                     /locus_tag="LP493_000964"
     CDS             complement(23725..24648)
                     /locus_tag="LP493_000964"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HBL2133128.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            24844..25449
                     /locus_tag="LP493_000965"
     CDS             24844..25449
                     /locus_tag="LP493_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL2133129.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            25757..26773
                     /locus_tag="LP493_000966"
     CDS             25757..26773
                     /locus_tag="LP493_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBL2133130.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            26914..28215
                     /locus_tag="LP493_000967"
     CDS             26914..28215
                     /locus_tag="LP493_000967"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HBL2133131.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            28261..28923
                     /gene="deoC"
                     /locus_tag="LP493_000968"
     CDS             28261..28923
                     /gene="deoC"
                     /locus_tag="LP493_000968"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBL2133132.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            28944..29342
                     /locus_tag="LP493_000969"
     CDS             28944..29342
                     /locus_tag="LP493_000969"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBL2133133.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            29408..30490
                     /locus_tag="LP493_000970"
     CDS             29408..30490
                     /locus_tag="LP493_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL2133134.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            30702..32264
                     /locus_tag="LP493_000971"
     CDS             30702..32264
                     /locus_tag="LP493_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2133135.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            32257..33390
                     /locus_tag="LP493_000972"
     CDS             32257..33390
                     /locus_tag="LP493_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2133136.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            33390..34346
                     /locus_tag="LP493_000973"
     CDS             33390..34346
                     /locus_tag="LP493_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2133137.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            34445..35611
                     /gene="deoB"
                     /locus_tag="LP493_000974"
     CDS             34445..35611
                     /gene="deoB"
                     /locus_tag="LP493_000974"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBL2133138.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            35635..36453
                     /locus_tag="LP493_000975"
     CDS             35635..36453
                     /locus_tag="LP493_000975"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBL2133139.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            36470..37177
                     /gene="deoD"
                     /locus_tag="LP493_000976"
     CDS             36470..37177
                     /gene="deoD"
                     /locus_tag="LP493_000976"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBL2133140.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(37475..38161)
                     /gene="gpmA"
                     /locus_tag="LP493_000977"
     CDS             complement(37475..38161)
                     /gene="gpmA"
                     /locus_tag="LP493_000977"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBL2133141.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(38333..38914)
                     /locus_tag="LP493_000978"
     CDS             complement(38333..38914)
                     /locus_tag="LP493_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2133142.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(39047..39730)
                     /gene="rpiA"
                     /locus_tag="LP493_000979"
     CDS             complement(39047..39730)
                     /gene="rpiA"
                     /locus_tag="LP493_000979"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HBL2133143.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            40049..40462
                     /gene="rpsL"
                     /locus_tag="LP493_000980"
     CDS             40049..40462
                     /gene="rpsL"
                     /locus_tag="LP493_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HBL2133144.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            40546..41016
                     /gene="rpsG"
                     /locus_tag="LP493_000981"
     CDS             40546..41016
                     /gene="rpsG"
                     /locus_tag="LP493_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HBL2133145.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            41110..43197
                     /gene="fusA"
                     /locus_tag="LP493_000982"
     CDS             41110..43197
                     /gene="fusA"
                     /locus_tag="LP493_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBL2133146.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            43369..44556
                     /gene="tuf"
                     /locus_tag="LP493_000983"
     CDS             43369..44556
                     /gene="tuf"
                     /locus_tag="LP493_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBL2133147.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            44963..45271
                     /gene="rpsJ"
                     /locus_tag="LP493_000984"
     CDS             44963..45271
                     /gene="rpsJ"
                     /locus_tag="LP493_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HBL2133148.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            45302..45931
                     /gene="rplC"
                     /locus_tag="LP493_000985"
     CDS             45302..45931
                     /gene="rplC"
                     /locus_tag="LP493_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HBL2133149.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            45959..46582
                     /gene="rplD"
                     /locus_tag="LP493_000986"
     CDS             45959..46582
                     /gene="rplD"
                     /locus_tag="LP493_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HBL2133150.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            46582..46872
                     /gene="rplW"
                     /locus_tag="LP493_000987"
     CDS             46582..46872
                     /gene="rplW"
                     /locus_tag="LP493_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HBL2133151.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            46911..47744
                     /gene="rplB"
                     /locus_tag="LP493_000988"
     CDS             46911..47744
                     /gene="rplB"
                     /locus_tag="LP493_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HBL2133152.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            47787..48065
                     /gene="rpsS"
                     /locus_tag="LP493_000989"
     CDS             47787..48065
                     /gene="rpsS"
                     /locus_tag="LP493_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HBL2133153.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            48088..48435
                     /gene="rplV"
                     /locus_tag="LP493_000990"
     CDS             48088..48435
                     /gene="rplV"
                     /locus_tag="LP493_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HBL2133154.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            48449..49105
                     /gene="rpsC"
                     /locus_tag="LP493_000991"
     CDS             48449..49105
                     /gene="rpsC"
                     /locus_tag="LP493_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HBL2133155.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            49108..49542
                     /gene="rplP"
                     /locus_tag="LP493_000992"
     CDS             49108..49542
                     /gene="rplP"
                     /locus_tag="LP493_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HBL2133156.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            49532..49720
                     /gene="rpmC"
                     /locus_tag="LP493_000993"
     CDS             49532..49720
                     /gene="rpmC"
                     /locus_tag="LP493_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HBL2133157.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            49745..50011
                     /gene="rpsQ"
                     /locus_tag="LP493_000994"
     CDS             49745..50011
                     /gene="rpsQ"
                     /locus_tag="LP493_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HBL2133158.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            50069..50437
                     /gene="rplN"
                     /locus_tag="LP493_000995"
     CDS             50069..50437
                     /gene="rplN"
                     /locus_tag="LP493_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HBL2133159.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            50474..50782
                     /gene="rplX"
                     /locus_tag="LP493_000996"
     CDS             50474..50782
                     /gene="rplX"
                     /locus_tag="LP493_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HBL2133160.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            50810..51349
                     /gene="rplE"
                     /locus_tag="LP493_000997"
     CDS             50810..51349
                     /gene="rplE"
                     /locus_tag="LP493_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HBL2133161.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            51368..51553
                     /locus_tag="LP493_000998"
     CDS             51368..51553
                     /locus_tag="LP493_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HBL2133162.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            51589..51987
                     /gene="rpsH"
                     /locus_tag="LP493_000999"
     CDS             51589..51987
                     /gene="rpsH"
                     /locus_tag="LP493_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HBL2133163.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            52019..52555
                     /gene="rplF"
                     /locus_tag="LP493_001000"
     CDS             52019..52555
                     /gene="rplF"
                     /locus_tag="LP493_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HBL2133164.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            52716..53072
                     /gene="rplR"
                     /locus_tag="LP493_001001"
     CDS             52716..53072
                     /gene="rplR"
                     /locus_tag="LP493_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HBL2133165.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            53093..53593
                     /gene="rpsE"
                     /locus_tag="LP493_001002"
     CDS             53093..53593
                     /gene="rpsE"
                     /locus_tag="LP493_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HBL2133166.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            53608..53787
                     /gene="rpmD"
                     /locus_tag="LP493_001003"
     CDS             53608..53787
                     /gene="rpmD"
                     /locus_tag="LP493_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HBL2133167.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            53831..54271
                     /gene="rplO"
                     /locus_tag="LP493_001004"
     CDS             53831..54271
                     /gene="rplO"
                     /locus_tag="LP493_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HBL2133168.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            54271..55566
                     /gene="secY"
                     /locus_tag="LP493_001005"
     CDS             54271..55566
                     /gene="secY"
                     /locus_tag="LP493_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HBL2133169.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            55628..56275
                     /locus_tag="LP493_001006"
     CDS             55628..56275
                     /locus_tag="LP493_001006"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HBL2133170.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            56466..56684
                     /gene="infA"
                     /locus_tag="LP493_001007"
     CDS             56466..56684
                     /gene="infA"
                     /locus_tag="LP493_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HBL2133171.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            56717..56833
                     /gene="rpmJ"
                     /locus_tag="LP493_001008"
     CDS             56717..56833
                     /gene="rpmJ"
                     /locus_tag="LP493_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HBL2133172.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            56851..57216
                     /gene="rpsM"
                     /locus_tag="LP493_001009"
     CDS             56851..57216
                     /gene="rpsM"
                     /locus_tag="LP493_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HBL2133173.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            57244..57633
                     /gene="rpsK"
                     /locus_tag="LP493_001010"
     CDS             57244..57633
                     /gene="rpsK"
                     /locus_tag="LP493_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HBL2133174.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            57713..58651
                     /locus_tag="LP493_001011"
     CDS             57713..58651
                     /locus_tag="LP493_001011"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HBL2133175.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            58679..59059
                     /gene="rplQ"
                     /locus_tag="LP493_001012"
     CDS             58679..59059
                     /gene="rplQ"
                     /locus_tag="LP493_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HBL2133176.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            59331..60170
                     /locus_tag="LP493_001013"
     CDS             59331..60170
                     /locus_tag="LP493_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBL2133177.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            60146..61015
                     /locus_tag="LP493_001014"
     CDS             60146..61015
                     /locus_tag="LP493_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBL2133178.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            61005..61802
                     /locus_tag="LP493_001015"
     CDS             61005..61802
                     /locus_tag="LP493_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBL2133179.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            62005..62751
                     /gene="truA"
                     /locus_tag="LP493_001016"
     CDS             62005..62751
                     /gene="truA"
                     /locus_tag="LP493_001016"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBL2133180.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKVRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            63416..63653
                     /locus_tag="LP493_001017"
                     /pseudo
     CDS             63416..63653
                     /locus_tag="LP493_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299509.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(63797..64573)
                     /locus_tag="LP493_001018"
     CDS             complement(63797..64573)
                     /locus_tag="LP493_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBL2133181.1"
                     /translation="MNIHHIRNATAILDYGGKKFLIDPMLAEKGTLPPFISKGPFPSP
                     RKDQMNPLVDLPMPVEDIINGIDAVIVTHLHLDHWDDIAKEVLPKEIKLFVQDENDAN
                     EIRLYGFKNVEVLREDTVFESIQLVKTKGKHGRGEILNYVGNVCGIVFKHSTEKTLYF
                     TGDTVWYEAVKQTIDQYNPEIIVANAGDNHFLVGESLIMGKDDLYELHKAIPDSTIIA
                     VHMEAVNHWGLSREELKSFNKEKGISEKVLVPEDGDNIFI"
     gene            64696..65103
                     /locus_tag="LP493_001019"
     CDS             64696..65103
                     /locus_tag="LP493_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HBL2133182.1"
                     /translation="MLDQTDINIIEELSKNSRITMKELGEKVHLTGPAVSARVTKLEE
                     SGVIENYTVKLNMEKLGFSIHAFLIIITQNLNHKPYLSFIKNHEKFLIRNYKISGGGC
                     YLLECRFTSKKSMNSFLEQLNEYANYKLSIVID"
BASE COUNT        20822 a        11647 c        13797 g        19182 t
ORIGIN      
        1 accacttctg tcacaacctc ttattttgat tagaacttgc gaaaataaac cggttaaagt
       61 gtgtctagcg caagagattt gctataatag acgataaggg taaaatgtaa cgagaagggg
      121 ttgaaaaatg tgtatcaaat tgtaacagat tcttgttgtg atctgccata ccatgtatta
      181 gcaaaagaaa aagttgattt tttatcaatg aatctccaat tgaatgatca agagttagta
      241 gatgacctcg gaaagacatt caattatgac cgctacatga atcagctgaa aaatggtgcg
      301 atgcctacga catcacaaat caatgttggc cgatatttag aatttttccg ttcttatgcg
      361 gaaaaacaga ttcctgtttt atatgtggct ttttccagtg gattaagcgg ctcttacagt
      421 agtgcgcttc aagcggttga attgctgaag gaagaatatg aagaccctga gatctatgtt
      481 tttgatacaa aagctgcaag tattggggaa gggcttttag tattggaagc tgtaagattg
      541 aaaaaagaag gtaaaagcat cgaagaaacc ctagagtggc tggaaagtaa ttatttgaaa
      601 gtccattcat gggtaacagt agacgatctg aaatatctag aacgaggcgg taggatttcc
      661 aaagcaagtg ctactcttgg cagtctattg agtgtaaagc ctattattac ggtggataaa
      721 gaaggaaggc tgacgaatgt tgacaaagtt cgaggaagaa acaagtcgat ccagacaatc
      781 gtcaatgaga cggtaaaaac aatcgttgca ccacttgatc aaatcgttta tgtggcttac
      841 gctggggatc tagagagcgc ggagaaggca aaacggcttt tggaagagca gataaagatg
      901 aaagatgtga agctttatcc cttaggacca acgatcgcca gtcacacagg ctatggctgt
      961 atcgcgattt tttcgatggg aatcagtcga taaaagcagt aactcattct gtaaaaaagc
     1021 ccagaaattg attgtaacaa aaacagcgac tcttaaaaga tagatgagca tcctatctct
     1081 tagaggtcgc tgttttttta ttttttaagc taaataggcc attatgccca taactcgttc
     1141 aattgttttt gaatatctgc attttccaaa aattcatcat atgtcgtatc agctcgatcg
     1201 atcacacctt tatccgaaac ggcaatgatg cggtttgcca atgtttggat aaattgatgg
     1261 tcatgtgacg caaataagat tgagccagta aatgccatca agccgtcatt caatgctgtg
     1321 attgattcta agtctaaatg gttcgttgga tcatctaata caagtacgtt agctttcgaa
     1381 agcatcattt ttgaaagcat gcaacggact ttctctccac cagataaaac attcactggt
     1441 ttcaatactt cttcaccaga aaacaacatt cttcctaaga agcttcttaa gaaggtgtta
     1501 tcatcttctt ctttacttgc atattgacgc aaccagtcta aaatcgttag atcagtatcg
     1561 aattctttcg ttgtatcctt tggtaaataa gaattacttg ttgtcacacc ccaacgtact
     1621 gttccagtat ctggcgtaat ttcacccatg ataactttga atagcgttgt tgttgttata
     1681 tcattttctg cgacgaaagc gaccttgtct tctttgctca aattaaaaga tatatcatct
     1741 aaaattttct ttccatcaat cgttacactt acattttcta cctgcaataa gtcgtttcca
     1801 atctcacgtt caggtttgaa tccaacgaat ggataacgtc tagaagaagg ttggatatcg
     1861 tctaaagtaa ttttttcaag cattttttta cgtgaagttg cttgttttga ttttgatgca
     1921 ttcgcactaa agcgggcaat aaattcttgg agttctttga tttgttcttc ttttttggca
     1981 tttgcgtttg cttgaagttt agccgctagt tgactagatt ccaaccaaaa atcataattt
     2041 cctacataaa gtttgatttt accaaaatct agatccgcca tatgtgtaca tactttgttc
     2101 aaaaagtgac ggtcatggga tacaacgatc acagtatttt caaaattgat caaaaattct
     2161 tccagccaat tgatcgattg gatatccaga ccgtttgttg gttcgtctag caaaagaaca
     2221 tcaggtttac caaatagtgt ttgtgctaat aacactttta ccttttgtcc accagttaat
     2281 tcactcattt gctgatggtg caattcttca gggatgttca gaccttgcag taaaacagct
     2341 gcttctggtt cagcttccca tccattaagc tcagcaaatt ctccttctaa ttcagctgct
     2401 cgaataccat cttcgtcagt gaaatcctct ttcatgtaaa tcgcatcttt ttctttcagc
     2461 acttcataca gacgcttgtg tcccatgatg actgtttcaa gtacagtata gtcttcatag
     2521 tcgtaatggt tctgtttcaa tacggccatc cgttcatctg gtcccatagt aacggaacct
     2581 gtggaaggct gcagatcccc tgataacact ttaaggaacg ttgatttacc tgcaccattt
     2641 gcaccaatca agccatagca gtttccgggg gtaaatttaa tattcacatc atcaaatagt
     2701 ttgcggtctg aaaagtgcaa actcacatca tttacagtaa tcaatttttt tcctcacttt
     2761 tatcattatt agttttgaca agtcttatag aattatatag gggaaaggta aaagattcaa
     2821 ggcaatcgaa cattctttgt gtttcacgtg aaacagaatg aaaaaaataa aaataaaagc
     2881 ggagcgaaaa tagctactat aggatttatt agtttgcaac agcataattt ttgacgttat
     2941 ttataagagg gagtactata aaactgtaaa agaaatgaaa gaaggattga aaatggatga
     3001 aaaaagaacc atcgactggg gctcattgat tttgggaatt ttatttgtac ttgtctcatt
     3061 gttatcattt caagaccctg tcggaaattt agttgcaatt gtagtagtct ttgcgatttt
     3121 tgcctttatt aaagggatat ttgaactgtt tgtacggaac agattaaaag agctaacagg
     3181 atataaagga aagatgccct taataatcgg gatcatcgat attctagttg gcgtcttttt
     3241 cttattcaat attggtgcag gagtcgcagc attgcctttt gtttttgcag tatggtttat
     3301 tgctgattca gttttagcgt tatttactgc tgacttggca agaggagtaa gtgaaggata
     3361 ttattggttt acgatcatcg tcaatatttt aggaatttta ttaggaattt tcttattgtt
     3421 taatccaatt tcttctgcgt tgacattaag ctttttagtt ggattctatt ttatgttatt
     3481 tggtatcaca catatcgtct atgcatttag ataagtaaaa tcaaacaaat aaaaaagccg
     3541 gcttccgatt acagttttac tgttgtaatt ggaagccggc ttttttatca tggacaaata
     3601 tgcacgaggt gatttttagg tgtcgagaca aatttatgca aaaatgtgag aagctatata
     3661 cacaaatttt atcttaatac tcgaagcata gcgcagttgt cacaacctct tttcatataa
     3721 ttcattcaat actggcaaat catggacttc atatttttct ttgaatgctt ggatttcttc
     3781 ttcagaatat tttcttggat ctaaatgcag atcttctact ggcaatgggc gcttgttatt
     3841 gatcttcaca tcgattacta caggacgatc tgattttgca gctgcatcaa aggcaaatcg
     3901 aagttgcgag tattctgtga ctgtaaagct atttgccccg agcgcttctc caactttacc
     3961 gaaatctgca tcttctaaaa atacaccaaa tttcttttgt tccgtatctt cttgttctgc
     4021 ttcgatgaaa ccaaaagaat cattcgaaaa gacaacatta ataattggaa gctgatattt
     4081 gacttgtgta atgatatctt gcatgaccat agcaaacccg ccatcaccac ttaaggtaaa
     4141 tacttgtttt tctgggtagc ttagttgtgc ggcaattcct cctggcacac cattacccat
     4201 agttgcgaac catccagatg tcgtatgttt ttgtttaccg ttcatattca ataaacgaat
     4261 agaatggata gtcgtgttac cgacatctgt gacgaaaatc gcatcgtctt cagcaatacg
     4321 attgatttct ttatagacag cctctggacg aatcggttct tcctctcgat cttcaaaaga
     4381 tttcaaccaa tttacccatt tttctttatt ttcttgattt gctaggtacc agctatcagc
     4441 agggcgagca tcccctaact cgacaagtct ttgcaaagct gtgtttgcat caccgaggat
     4501 cgacaaagat gtttcatggc gtcgtccaaa ttttgacgca tcgatatcga tttggataaa
     4561 ttcagcagtt ggattaaaaa atgcacgtcc aaatgggaag tcgctaccga caaataagat
     4621 cagatcggct tctgccaatg cttcatttcc gggtttagta gcgacacgtc cagcaaaacc
     4681 aagaaagttt tcataatcat caggaataat tccttttgct agaacggaag cgacaacagg
     4741 aactgaaaaa tgttctgaga attctttgat ttgcggaaat ccgtttcgcg ttccttgacc
     4801 aacataaaga actggttttt ttgctttttc aagataaggc aaagcagcta gcaaatcttt
     4861 ttcttctggt aatatcacac ttgttttgtg agtgtgagcg gtggagaaag gttgttcgtc
     4921 aatttcttca aaaccaagat caacagggat agtcacgata gccacgcctt tatgctcata
     4981 ggcggcttta atggcttcat ctactacatg cggaagactt tgtggtgtca tgactgtacg
     5041 attgtatacg ctaacatctg cgaaaatagg attttcattt agttcctgga aagagttata
     5101 gttcatggat gtagaagcaa cttgtcctaa gaacgctact agaggcacat ggtccatctg
     5161 tgcatcatac aaaccattga tcaaatgtgt cgcaccaggt cctgcagagc cgaagacagc
     5221 gccgactttc cccgttaatt ttgcatctgc agcggctgcg agtgcgccga cttcttcatg
     5281 acgaacttga atgtagttga tttcggtttt ttcttgatat agcgcatcca taattgaatt
     5341 gaaagatcct ccgggaatgc cgtaaatatg gtcgataccc cagctttcaa gaacttttac
     5401 cattgcgatt cctgcattga tttttgacat ggtgtttcac tcctttagca atgatgatac
     5461 ataaattttt tgtatctaga gtatagaact ttttatcgaa aatcccaact aattcgtctt
     5521 ttcacaaaaa tgtagtcatg tttttgggaa tatgctagag tagtacatag atagattcaa
     5581 gagaggggaa tggcatggtt gaatggctat tgagacttga accttggcag caagcacttg
     5641 ctgggacagc ttttacttat tttatgacag ctcttggtgc cgggttggtt tttttcttta
     5701 aagaaatcaa aaaagaagtg ctaaacttga tgttaggatt tgcttctggt gtcatgattg
     5761 ctgcaagttt ttggtctttg ttagatccgg ctattacaaa agcagaagaa aatggagata
     5821 ttgcttggct agttgtaagt attgggtttg gtttaggcgg tgtgttttta tatatggcag
     5881 ataaaacact gccccatatg cattttggac cacaacatga agcagaagga ttgcctaccc
     5941 atttaaaacg gacgatcttg cttgtttttt ctattacatt gcataacatt cctgaaggtt
     6001 tagccgtggg ggtagcattc ggtgcagcag caactgcgga taatccgaca gccgctatat
     6061 tagccgctgt ttcggtggcg ctaggtattg gtatccaaaa cttcccagaa ggagcagctg
     6121 tatcaatccc gttgcgacaa gaaggtctga gtcgtaaaaa ggcctttgtt tacggacaag
     6181 cttctggaat cgttgaacca attgctggag tgattggagc gctactagta acgaaagtgg
     6241 agctgctgct tccttatgca cttgcttttg ccgcaggagc aatgatttat gtcgtggtgg
     6301 aagaattgat ccctgaagca cagcagacat tgtccagcaa acatcatttt gcagtttttg
     6361 gcgtcatgag tggatttatc attatgatga ttttggatgt ggcattagga taaataaaaa
     6421 aaatatatat gatatatcaa atagggccgc gaacttatat cgcgacccta tttttttagt
     6481 aagttatatc ataatgaagt gaatggtatc atacattaat aatagttttt tctatgtgta
     6541 tttcctttga tccagcgaac aagccagatg ataagtgcga ttgggattag aactttgacc
     6601 gcaaaccata aaagcccgct taggacactg acaaaaagac tgatgacgaa gctagctgca
     6661 attagcacta aaagaaccat gaagatattt aagaacatat ttttttgacg catacaaaac
     6721 cctcctcttg ttcattcttt actatagaaa aagtataaca gggattgttt aaaaacacct
     6781 ccaactgaag actgattttt acttcatcta cttaaatgat caaacaattg ctttttctct
     6841 ggtttatcat ctaaaataga gcggaaaagg aggagaatat catgcctaaa aatcgtcttg
     6901 aagcatttac agatgctgta atcgcgatta tcatgactat tttagtttta gaacttcatg
     6961 aacctaacgg agacacgtgg gaggcgctcg ctgcattagg ttaccgattt tttatctata
     7021 ttgtcagttt tatcatttta gcgatttatt ggaacaatca tcatcattta tttcaagttg
     7081 tacataagat aaatggacgg gtcttatggg cgaacagttt ctttgttttt gcgctttcgc
     7141 tttttccgtt tgcaacttca tggatcagtg agtacatcaa tagcctggct ccagaaatga
     7201 cttatggttt tgttaccttg accgctaata ttgcgtatta tatcttggca aaagaacttg
     7261 tcaaagcaaa taaaggccac gagaaagcat tgaaggcgat gttgaataat tacaagaaat
     7321 cgtatctatc gattggtttg aatgtgttag gaattgtctt agggtattta gtagcgccag
     7381 tagccgtgct gatcgcaaac atcgtgattc tagctgcttg gatcatccca agtcgtacca
     7441 tcgaatcaca atatcggtaa aatgatccgt gtttaaaatt taagagaaaa atatagaaaa
     7501 aataaataaa cgatcaaata tccgagtgat actagtattc aaagagggat gcagatggat
     7561 caaaaaagaa ttcatgtagg actgattact agttttgtca cgatgcttat ttatttggat
     7621 caaggtcatt tgacttggac agtagttggt gtcgtaggat ttttgacatt attcacagca
     7681 ataaaaaaat aaacatcttt atgtaatctg atgttctatc tatttaagaa aagcatgttt
     7741 acagcagtat gattctgttg taaacgtgtt tttatttgtg gaaaatttaa tttttagaaa
     7801 agtgtatcga aaaatagata gttagttttt ccacagtgga taacttcgta agagataaaa
     7861 ataaaaaatt agtcaaagaa gggcgtatag atttcttttg ataggagata tacaacagaa
     7921 atgaataaat attaacgtgt tttcaaacag tataaaacgg tgtggttttt ggaataaaaa
     7981 aataacatat ctcattttac acttttgtta ttttatactt aaaaaataac gacacagaaa
     8041 ataccgtgtc tcagatttct ctactacttc taaaaactac tgtttttttc ctttgaaatg
     8101 ccttcaaaaa gtaggatcag gcagaatata ctggcagaat caaggagaag ggagcctaaa
     8161 taaggagaaa aaccatagaa aatataaagt aattacttat aaaacaagct ttttatagaa
     8221 aaataatata cctgagtagg gtataaatta agacggaatt cctttctaga ttgagatatt
     8281 gactaggaag aatgttaaga ttttaagcct ttaagctaaa aaaaaaccct ttttgttaaa
     8341 taaggggaat atagcctgtc agtttcaaac tgcaagtcgt cctgctgcaa taatatagta
     8401 gattagagat gaaaatagat ttttttaaac caatgactga ataaaaagac cgtcatagat
     8461 acacattgga atgtgtctat tacggtcttt ttttacgaac gattttattg aagacggaca
     8521 gttcgggtca aaaataaaaa agctacgatc agaaataaga ataaaatgta tcccaaaata
     8581 atggctagac ggtctaactt atttgtcgat agatgtttgt ttagaagttg ataggcccat
     8641 aaacctatca gtcctcctgt tgtattagtt atcaaatcag tgatgtccgc tacgccaata
     8701 ccgaatagga attgaatcaa ttctgccaag aagcttacaa ggaaaataat ccctaatttt
     8761 ttagaaaaag aaagtctctt gaaattgaca ttcaaaagca ccccaaaagg aaaaaagaca
     8821 atcaagttat aagtggtctc acgtaatacc gtcgtatttt caaaagaaaa agtagaaaaa
     8881 gggacgagat tgacattgct gtaagaataa gtgagaaatt gtggaagatt aaatgatagc
     8941 ttgaataaaa tcaaccataa tagaaagaat aaataaatcc ctaataaaaa ttttgataca
     9001 taccgcatag acatctcctc catttaaaaa gtataccatc gaaaaccgct gaaaaatcat
     9061 aaaaaagtat gaagtttaag gaccaacgta gttatcgtac gaaaattaga agcttttttt
     9121 tgttgggaat ccggtttctt taacaaagct aagatagcga gttgcttgga aaagttgcta
     9181 tcttttttct gtcaaaacga ctcggaatgt tcgttttttg ttctaatttc tccaagttgt
     9241 ttactttttg atactaagtt tatgaaaaat caagaaatag ttgttatact aggtaatgct
     9301 gacaaacggg attggcattt catcttggtt cagctttttt tccaattact aggaaggagg
     9361 gatagattgt tcaagactta ttttcgtttc aataaaatac aagataatcc ttttcgtatc
     9421 atgaatctga tgctacttat ctttattgta ttatggttag gttacataaa tcatgatttt
     9481 ttgatttcaa gtttttcatc attagggatc tttacttttt tctattatca aaacataccg
     9541 atgaaatatt tgctgaaacg tatgtttctg atcggttgcg gactgttggt tgctttcgtt
     9601 ttggggatct tatcgactta tgttttatgg cttgaaccat ttgccgtagc tttggttgct
     9661 ttttccagca gattcgtgtt gcgattattc catatttcta aaccaggtgg cttgtttttt
     9721 gcgatgcttt ctgccatggg aacgagcatg cagctgccaa tcgctcaatt accgatcgtc
     9781 tcactttatt tttttatggg tgtcgttttt gccctgattg cggcagtgat tacaaaatta
     9841 ctggattcac ggcctgagca gacaattgaa aaagcaactt taaaagaaag atttcacgaa
     9901 gagcctttag tgatcattga ttctgttttc tacagcgctg ccttatttct ttccgtttat
     9961 gtcagtcacg gcttgaatct gcataatcct tattggttga ccttgtcatg tgcatcgatt
    10021 ttgctagcag aaaacttgga tgcgatgaag catcgacaag tccaatatct gattggatcg
    10081 atgggtgggt tatgtgtgtc ggcattcttg tcatttgtgc cgtttacgca gttgcagacc
    10141 atttttctga tcacttttct atatggaatc gcacaatttc tagttgctag aaattatgca
    10201 gttgctaata tttttcttaa tccgatggcg ttgatgctat ctacacttat tcgtggagca
    10261 tacttgattt ctttgatcga atatcgtttt ttagggatcg tcataggaag tttcatcggt
    10321 ttaggtgttg cgtgggtaat gacggttggt ttgcaacatt atttaacggt tgttcgtcaa
    10381 aaattagaat agaaggacaa atatatgtgc caaaagaggt tatgacaaga tttttgtcac
    10441 aacctctaat tcaaggtgtt caaaagccag attctcagca ttaagtcaaa ttcacacaaa
    10501 aatgtggaaa ggaactttca aaaaaatttt atatttattc tatcaaaaaa ttttgtttat
    10561 gatggtaact gaataaactt tcctgagatg gtcaatgctt tccttgaaag tcttacagat
    10621 attctttctt catagaaagt ttaagtttta tagttagtgt acaataaaag tatgtttata
    10681 ccatatggtg tccggataat cagtcattta aacaatgagg ttcaaagata tgaaaagggg
    10741 aaatttgatg aagaaaataa gcaatgaaat ccaaattctg gcagaaactt taactcttcc
    10801 caaagtcgtt atagagcaaa tgattgtaca agcaaaaaac atccttgatg aggtgtttga
    10861 gcaatatagt catgaactaa tggatcctaa taaagcaaag gcgactgcaa agaaaataga
    10921 caaagtctat gaagaggaac cttttgcagc attagctatt tatctatatg cagcttctca
    10981 aagttggaaa aaaatttatc aaccattgaa gattccaaga actatctatt tggcaacaat
    11041 gaatgctttt actagattta ttcatgaaca tttccaagta acaggaagct atcgctttga
    11101 ccgtggtttt tggatttggc attacactag tggcttgatc tttcggattg gtgaattgga
    11161 gtacgaaatg acatattttc cgaaagggta cacggatcta agattagaag gaaagcagtg
    11221 cctttctctt catattcctt ccgatgcaga tttatctcag aataagataa gagatagtta
    11281 cgaaagtgcc attcgttttt ttgaacttta ttttcctgat taccattacc aagtgatgta
    11341 cacagatact tggttactat cacccaatct tactaaatgg ttgaaaaaag agtcaaaaat
    11401 ctgtcttttt gcagccgatt atcgattatt atcagttgat gaacaggacg atagtggagt
    11461 cccttggatc tttggacgag tagatgccca aatacatgat tatccagaaa gtacgagttt
    11521 acagcgacaa gcaaaagagc aattgcttgc aggcgagcac attggctctg gcttaggtat
    11581 tcttacttca taagtttagt acttcgaaat agtttaaaag agcgtgagac aaaagtaaag
    11641 aacacttttg tctcacgctc taaacacgta taaacggcgg aagcagaagc aactccttcg
    11701 gaaataagct gaaattcaca aaaatttgaa aagcaatttt cgtgaatttc ttcttatttc
    11761 ttggagttaa acgcttctgt cccagcctct tttttagtgt tctatcgaac acacagtacg
    11821 ttcaataggt aaactagcta taacaataga tattaaagtt aacggacaag agggcctttt
    11881 ttaggtagct aaaacgtaat aatgaaaatt tatttccaga gataggagtc aatcagctag
    11941 tctgatcgac tgttttaaca agttgacttt cattttaact tttgatacca tttaaaacac
    12001 aaatcgtaat tgtttcgatt tgtgtttttt agcatgacta caatcaaaga agaaagtggg
    12061 tcgtccatat ggaaaaaaca gatatctcaa gtgcataccg ccgcttgaaa agcccaaata
    12121 tcaaaacacg aaaacgtgcg ctgaagatca tcaaagatgt gaaacggaat agtgggaaaa
    12181 ggtaagaaga aggaaactta attaaaaaaa tagccgaaaa acgtttttcg gctattttca
    12241 ataatcggtt tttgtgtaag gtttccgaaa gaactgctgt tgattttcca tttttaacat
    12301 atgataaatt ggtagaatct ttcttttcaa attgatacca ttccctaatt ccagttatat
    12361 agttaactac agaaccacaa agcacgtacg tttataaaag tattatctgt agttattttt
    12421 caattccctt tcaacctctt attttgacca gtagtattga tcactttacc ttttaacacc
    12481 tttgttcgtt tttgaaacat ttttagtcaa gaatggaaac gtaactacat aatcaaaggt
    12541 tttgcgaaat atttcatgaa atatttcatg tagaagcgag caatacggtt gcaaataacc
    12601 attatcgttt aataagcagt tacgaaagct cccaatatct ctaacgttca gctcactcca
    12661 tttcttttct tcaaaaaaat cagtgattcg tatctctttc tatttgtcga aaaagttaac
    12721 tttaaaaagt aacgccgaaa aaatatgcaa aaaaataaaa aagcagttac tattgctaga
    12781 ataacatcaa ggaataataa gttttggttt tcagataata gtcgataagt tgtgtattgg
    12841 aattttagat acagtaataa agtatttttc atgaaatttt gtgagaatca ctattacaag
    12901 tatctttaat aaaattaatg gttaaggagg aacttaaagt agaatgtaaa tgaatagttg
    12961 tagtcagtcg attgtgatac tagactcaaa gttgcaggaa taagtttttc aatttgtgat
    13021 tggaagataa aaaatgaaaa agaagggctt ttttttatac tttgttgatt gtagtgttta
    13081 ttttccctct gtttagccaa gtaacatttt ctatgactca accagtttca agtgaggaac
    13141 atgataacct ttttcgtgct acagaagagt ttaagaaata tcaggaaaat attgttccgg
    13201 agactccatt agctagtgag ccaattactg atattgatgg aaaccaaata ggatggtata
    13261 tacagtacga agttatggtg gtaaataatg actcaatagt aaaaaataca gtaggcttag
    13321 agctaacacc gattgaaaag gtgagttcat tgttaacgta tatttatact gatgaaagtg
    13381 acgagactga gatcatttta acggattact caaaaattgc tactgataaa aagtatatat
    13441 tgtggatgta gacactagtg aaatacttta tgatatagaa attgatgaaa atttactaga
    13501 tgtagcacaa gaaatcgatc atcaaaagca ggaagctatt cgatatgctg gtagaaaagg
    13561 gaaaagaaaa tatttattac gtgaatgtag caaaagttag agaagatgaa aatgagtgga
    13621 aagaattcaa gagtcgctac tcaattaact cgactccgac atttacagtt tacagagaag
    13681 gatcgataga aaaaactgtt ttttggacta aagaaagtgg aatgtcttta gctgaagtag
    13741 aagagttttt ggattatgtt agtatgcaac agtaagggag ttcttattat gaaaaatttt
    13801 gacacatatt atgttattgt tttttcgata tctttgctgt taatattact aactttaatg
    13861 cagtataaag agtatccaga gtattttatt ttaacttttg tatatttagt aagtagctac
    13921 acacttctat ataaattcag aagttcttct agagtttcta aagtttgttt cttaattagc
    13981 ttattgattc tataatattt ttgatttata taggaaatta aaaatattat agaatcaaca
    14041 ctcagagaac gggttggttt ttaatagatt taataagtac tgataatgaa atttctcctg
    14101 gttgggaaaa cgaagttggt taccctgtag aagaattttt tcaagattac tttgcggagt
    14161 atgccgatag gataatgaga gattacgtaa cagataaaac tcaagaagtc atcaatcaat
    14221 cccagtcatt aaatgaatta tctgataagg cgaaagaaga agcagttgcc attatttctt
    14281 cagggattag tgactatatt gatatgagtg gtgaaatcaa ttatggcgat aaagacaaaa
    14341 ttgtacgcat gataaaagct tttatcaaaa cttttgatgt gaaggcagat cttaagttta
    14401 atgatactta cctagtagga aaattaatta atatccttgg gacagagaaa gatacggaaa
    14461 cgtttatttc ctctttgtct atgttgttta cagataagca tttttcaact cagcttggtg
    14521 gagaggaact agtggaaatc ttttaaccat tacgcccagc attaataaaa gtatatcaaa
    14581 aaagtactcc tgatgatttt taagattggt ttgagaaata atgtgaaaac actattttta
    14641 atgttaatta tagatagaga tgaacgcgtc atatggttaa aagaatgaaa aagtcaaaga
    14701 tacactgcta tatttcacta aggatatagc agtgtatctt tcatgtcgtt tcactggcag
    14761 ttttttataa aaggaggtgt gcatttcagt tgcttttctt tggtagttag ttgaatcgtt
    14821 taagaattaa cggatgtggc agacaggtgc tctgtccaaa aaccagtaaa atctttgatg
    14881 gttccatctt tatttagctg tgcctgttca aatactgttt tgtttttacc gaatggatca
    14941 attgcaataa ttgttccgat ccccgcacgt ttggcagcaa gtaatcctga gtaagcatct
    15001 tcgataacaa gacaatcagc cggagctaag ctcagtttgt ctgccgcttt aagaaaaata
    15061 tccggttgcg gtttcccagg gaaagagccg tcgtcataga caatcttgtc ccagtcaaac
    15121 cagcgggcta aatcgaaaat atcaaaataa aaagcaacat tctctttgac agtagccgtg
    15181 gcaatcgtta atggaatctg ttggtcagtc agctggtcaa gagtcgcttc aagccctttt
    15241 gtcaactgaa gctcgttttc attttgcaag caaagcatac gataatagct ttctttttct
    15301 tctgacaata cggcgatctc agaggcggtc aaatgctctg aaatgaaatg tttcaaaatc
    15361 tccgtattcg tccgaccatg aatatttttt aaaatatcct cgtctgataa accatctttt
    15421 gtatgatcat gtatcatatg cagccaagca gcttcatgca gatgagagtc caaaaacatt
    15481 gttccgttga aatcaaatat aatccctttc atagttacgc tcctatagtg gtattttcgg
    15541 ttgaatcagc aatttgcaga tcgacatatt gtgcatagtg ctcttgaacc tcccgcgaga
    15601 tctggcgatc cgtaatgagc agatcgaaat catgcaaatt ataaaacaca taaaaatcat
    15661 ctcgattgaa ttttttatta tcaacgagta gatatttctt acgggaatta tttagagcga
    15721 tctgctgtgc ttctccttct tcggtactgt aagtagagat cgcttcgttg tgaacgccat
    15781 ttgaactgat aaatgctttt gtaaacttta gtcttcttaa attgtcgttg gtgatcggtc
    15841 cgacaaatgc gccggtattt ttccggaaat caccgccaat cagtagaatt tctggtccat
    15901 ctgcttgagc aagaatatca aaaactggat aattatttgt aatgatccga attttcttgt
    15961 tcagtaaatg cgtcgccaat agttcgattg ttgtacctgg tcctaagaaa atcgtttctc
    16021 cctcgtgaat caaggaggct gctgtggcag caatttcttt tttttcttga atctgcagag
    16081 tggctttttc agtgtgagaa agttcttgat ctaaagtgta ggaaagactt tgagcccctc
    16141 catggacacg cagcagcttg cccgattttt ctaattcatc taaatctctg cgaacggtca
    16201 tatcagaaac atctaattga ttgatgattt cattaacggt aaggattcct tttttattga
    16261 ccatttctac gatagtaagc aatctttctt ttttcaacat tgtcttcacc tctaatttaa
    16321 ggataatcta tcatataaac ggacaacagt caatctaatt cgaacaaaag taaacattta
    16381 gggtggtttt tatgtttgtt acaatagatt ttattgctgt tttctggttt ttatgattat
    16441 ttgtgtttgt ttttgttgac aaatgttttg gatgcgttta caatgcaatc agttagaaag
    16501 agcgaaaact gattatagat ttgaggagag atgtacatgc ttaaattacc agaagatttt
    16561 atttttggcg gagccacagc agcctatcag gttgaaggag ccactaagga aggtggcaaa
    16621 ggcgctgttg cttgggatga ctttttagag gaacaagggc gattcagtcc cgatccggca
    16681 agtgattttt atcatcaata tgcaaaggac attgaattgt gtgaacgttt tggtgtaaat
    16741 ggtctaagat tatccattgc ttggagccgc atttttcctg atggagctgg gaaaccaaat
    16801 ccagaaggaa tcgcttttta tcatcgtgtg ttcgaagaat gtaagaaaag aaacgtaacg
    16861 ccgtttgtga cgttgcatca ttttgatacc cctaaacgtt tgtttgacca tggagatttt
    16921 ttgaatcgag aaacaataga agcatttgtt tcctatgcca ttttttgttt tcatgaattc
    16981 aaagaagtca aggtgtggag tacctttaat gaaatctatc cagttgcaac caatcaatat
    17041 ttgttaggtg ttttcccacc aggaatcaaa tatgatttta caaagatcgt cgcctgtctt
    17101 cataatatga tggttgctca tgcccgtgta gtgaactatt tcaaagaaaa cgaacttccg
    17161 ggtgaaattg gtgtagttca ctcattagag acgaaatatg cggcaacaga cgcgccggaa
    17221 gataagcatg ctgccttttt agacgatgca ttgtcgatcc gtttcttatt agatgctacc
    17281 tatttaggct attattcaac tgaaaccttg actgctcttg atgagatatg tgaagcaaat
    17341 caggccagct atcattttcc tgaagaagat ttcgttgaat tgaaaaaagc atccacgcgt
    17401 aatgactact tagggatcaa tcactaccaa tgccattttg tcaaagctta cgatggagaa
    17461 aatgcaatcc atcataacgg tacgggtgaa aaagggacct ctgtttataa agtgaaggga
    17521 atcggagaac gtatttataa agaaggaatt cctcgaactg attgggactg gctgatttat
    17581 ccagaaggtc tatatgactt gttgctgcga attaaaagcg attacccaca ttacaacaaa
    17641 atctatatca ctgagaacgg gatggggtat aaagatcagt ttgaagatgg cattattatg
    17701 gatcagccga gaatcgacta tttgagagtc tatttggaat ccttaagcaa ggcgataaca
    17761 gccggggtaa atgtgaaggg gtattttttg tggtcgctta tggatctttt ctcatggaca
    17821 aatgggtata acaaaaggta tggcttgttt tatgttgatt ttgaaaccca gaagcgttac
    17881 ccaaaagaat cagcttactg gtacaagttg gtcagtgaaa ccaaaacgat tatttaataa
    17941 gtgataatgg aggaagaaaa gatgaataaa gaggaattac aaatgcttgg ttttgagatc
    18001 gttgcatatt caggcgacgc tcgcagtaca ttattgaaat tattgaaaga agtaagacaa
    18061 ggaaactttg aacatgttga ttcggcgttg aaagaagccg acgaaaattt aacccttgca
    18121 cataattcgc aaacaaaaat tttagcggaa gaagcatctg ggaaagagat ggagatggga
    18181 ttcattttta tccatgggca ggatcattta atgaccactt tattgctgag agatctgatt
    18241 caagacttta ttgtactgta cagacagaat caaggatagg agaagaacgc tatggatgga
    18301 atcattaaac aaatcgaaaa agggaaacca ttttttgaaa aaatctcacg taatagttat
    18361 ttaggagccg ttcgtgacgg atttttaaca gcgatgccag ctattttatt ttcaagcatt
    18421 ttcattttga ttgctgcggt tcctgagatt tttggttacc aatggcctga atctgtctcc
    18481 acatggctat ggaaagtcta taattattcg atgggtgttg tagggttact cgtttcagca
    18541 accactgctc gctgcttggc tgattcgatg aatcgtcgct taccgaaaaa caaagtaatc
    18601 aacaccacct ctgtgatgct ggcctctgtg gtaagtttcc tgttgttaag cgtctctccg
    18661 attgaaggtg gattttcaac ggaatatatg gggacaaagg gactactggc ttcctttgtc
    18721 gctgcatttt taacagttaa tttatataag ttttgtgtgc tgaaagatat taccattaaa
    18781 atgcctaaag aagttcctgg aacgatttcg caaaccttcc gagatatttt tcctttctct
    18841 ttttcagtat ttgcggccgt tttaattgat ttaggcattc gacaaatctt ccaaatctca
    18901 tttgcagaag caatcattac ggtgctgcag ccgctattta cagcagctga cgggtactta
    18961 ggaatcgcta ttatctgggg agcgatggcg ctgttttggt ttgtcggtgt tcatggaccg
    19021 tcgatcgtgg agccggcaat tgcggcaatt atctatgcca atgtggaaac caatctgcaa
    19081 ttgttcaatt ccggtgaaca agcttctaaa gtactgacgg tgggtttagg gaattttgta
    19141 ggaactatgg gaggaactgg ggcaacattg gttgttcctt ttatcttcct actctttgct
    19201 aagtctaagc agttgaaggc agttgggaaa gcttccttta ttccagtaag tttcgctgtc
    19261 aacgaaccat tgctatttgc ggcacccatg attttgaacc cttatttttt tattccattt
    19321 ttgttaacac ctgttgtaaa cgtttgcctg ttcaagtttt ttgtcgatgt attgggcatg
    19381 aacagcttta tgtacgtttt gccttgggca actccagcac cgatcggttt ggttctagga
    19441 acgggcatgg gtatcttagc ttttgttcta gcagcggttc taatcgtcgt tgacttcctg
    19501 atctatctac cattttgcaa agcatacgat gctgtcttag tagagaaaga agcacaaaaa
    19561 gcagaggtga tcgcaaccga ggaaggtgct tctgccgatg tacgtgagga agtacctgtg
    19621 gcagcgagtc aagttatcag cgatgcaaat aaagaaatca atgtgttggt actttgtgct
    19681 ggcgcaggga caagtgcgat gttagctaat gctttaaaaa aaggtgcatc tgaatcgaaa
    19741 gcaccgatca gtgcaatggc gggtgcttat ggttctcatt acgaaatgct gcaggatttt
    19801 gatatggtgg tcttagcacc gcaagtcaat tcttactatg atgatatcaa agaagacacc
    19861 gatcgcttag gaatcaagct ggttgcgaca aaaggagcag aatatatcgg attaacgaga
    19921 gatcctgaaa aagctgttca gtttattctg aaccaatttc aataaaggag gagccataat
    19981 gaaaatggga atttggttgc gtaaagctgt tttatttgca gctgtgttag gggctttggg
    20041 ggctgtttca aaaactgttg aagcatctgc cagcgaattt attcgcggag cagatatttc
    20101 gatcctgtca gatatggaaa aatctggtgc aaaatattat gaagacgata tttcaaaaga
    20161 tgccttagag attttaaaaa ataatggtgt caactatgtt cgactgcgtt tgtggcagga
    20221 tccttataat agtaatggag aaagttatgg agcagggaca aatgatctgg aaacgacgat
    20281 tgaccttgca aaacgagcaa aaaatctggg acttaaggtg ctgctggatt ttcactacag
    20341 tgatttttgg gttgatcctg ggaaacagaa tcttcctaaa gcatggcaag gtctgacctt
    20401 tgaagaaatg aatacggcat tgtacgacta tacaaagaac gttctgtcgg aaatgaagca
    20461 gctggacgtt tatcctgata tggttcagat cggcaatgaa ctgaatagcg gaatgctctg
    20521 gccttatggc aagtcttggg gagaaggcgg gggagaattt gatcgattgg ctgctttttt
    20581 gaagtctggt atccaagctg ttcgagacac tcaacctaaa acaactccag taatgctcca
    20641 cttagctgat ggtggcgata caggagcatt tacttggtgg tttgatgaaa tcacgagtcg
    20701 aggtgtgtca tttgatttaa ttggagtgtc gtattatccg tattggcacg gttcaatgaa
    20761 tgaacttcaa accaatatga atgcgatcag ccaacggtat ggtaaagaag tgatcgtagt
    20821 tgaaacagct tatgggcata caacagcgaa tgccgatact atgccaaatg cttttggtga
    20881 agccgaagca gctgcggggg gatatgaacc aacaccgaca ggacaagcag agtatttgct
    20941 ggatcttgcc gatcggattc aggcagtacc gaataatcgc ggggcgggct tcttctattg
    21001 ggaacctctt tggtacaacg gaaatgtgag ttgggcaaca caagcaggta tgaattatct
    21061 cagtgttcaa tccactatgg gaaacgaatg ggacaaccaa gcgatgtttg attttgctgg
    21121 aaacgccttg ccaagcttgc gtgcgtttaa acaagcaggg gcgcaaataa atctagttaa
    21181 aaatgcaagt ttcgaaagcg atggaccaac gaccagtcct tccaattggc aaacctggtt
    21241 tcaacaagga accgctaagg gtacgatcaa aacggaagcg ggcacttttt ttggggacta
    21301 caaactaact ttttggcagg atcaagcata cgaggcatca gcttatcaaa atgttagtgg
    21361 cataagcaaa ggaacttaca cattgagtgc ctatgtaatg tctgggggag agtttgatac
    21421 taatcagtta tatatcaaaa attatggtgg agcggaacta aatactgcgg ttgttaaaac
    21481 aagtgaatgg acaaaaatta caatcaaaga cattccaatt acaacaggtg tttgtgaaat
    21541 tggggtttat agcaaggctt caggaaatgc ttggacgaac gttgattttg tttcattggt
    21601 gaaacaatag actgcggatc gtttcgattc aagatcggag gttcccttca gccacatcgt
    21661 tagcgtagaa ggcaggaatc gaacctgcac ctcgcctttg ccaaaaataa ccagaaacga
    21721 tttccagtca tttttaccaa aacgagtaaa gcaccagact tcatctacac tttgtattat
    21781 gctaaagaga gttcaacgat ttcgtaagaa gcaatgaaaa aattgcaaaa agttgtgcag
    21841 ataacataaa gtttgtttaa gaaagggtaa ccttagaatt ccgtcgtgaa tatgatttga
    21901 gcacttagat ggatagaaaa aagttctcgg aaaacagttc gtttttcgag aacttctttt
    21961 tatgataaga atgaaacaaa ttaacttata ttatagtctc ttttggtagg gaaccatctt
    22021 atttttaatg aaaatcaagc attttagcta ttgaagaatg ttgatttata gggattcccc
    22081 ctccatatta tgttggctct ttattcccac tccactgttg ctggtggttt agaagtgatg
    22141 tcatacacga tacggttgac gtgggctact tcgtttacga tacgtacaga gattttttgc
    22201 aagacttccc atgggatacg ggcaaagtca gcggtcattc cgtcgattga agttacagca
    22261 cggataccga ctgtgtagtc gtaagtacgt ccgtcaccca taacaccgac agagcggatc
    22321 cctggaagaa cagtgaaata ttgccagata tcacggtcaa gtccagcagc tgcgatttct
    22381 tcacgcaaga tagcatcaga ttcgcgtacg atttctagct tgtcttcagt gatttcgcca
    22441 agaacacgaa taccaagacc aggaccaggg aatggctgac gccaaacgat tgaatcaggc
    22501 atgcctaact gagtccctaa ttcacggact tcgtctttga ataatgtgtt taatggttcg
    22561 atcaattcaa attgcatatc ttctggcagt ccacctacat tatggtgaga tttgatcgtc
    22621 tgtgctgttt ctgtaccaga ttcgataacg tcagtataca acgttccttg tgctaggaaa
    22681 gagacgcctt cttcaccagc aagttttgtt gcttcgtcat caaaaacata tacgaattca
    22741 ttcccaatga ttttacgttt ttgttctggg tcagatacac ctttcaactt gtctaagaag
    22801 cgatctcttg cattgacttt gatgatgttc aagccgaatt ttccgcctag actttccatt
    22861 acttgttccg cttcgccttt gcgtagcaga ccgtggtcaa caaagataga tgtcaattgg
    22921 tcaccgatcg ctttttgtaa aagaacccca acgacactag aatcaacgcc acctgaaaga
    22981 ccaagcaaga cttttttgtc accaacttgt tcacggattt tttctacttg catatcgata
    23041 aagttatcca ttgtccagtt accttcacag tgacaaacat caaaggcaaa gtggcgcagc
    23101 aattcgattc cgtattcgga atgacgtact tctgcatgga attggatacc ataaaaatta
    23161 cgtgttgtgt cttggataga agcaatcgga caatctttgc ttgttccgac tgtttcaaag
    23221 ccttcaggaa ctttagttac caagtcacca tggctcatcc atactgtttg ttgttttggt
    23281 gtttctttaa acaagacagc ttgatcgctt gttacttcta acaaggcttt cccatattcg
    23341 cggtttttag caggctctac ggaaccgcca agtttgtacg tgatcaattg cataccatag
    23401 caaatcccta atacaggaat acctaaattg aagatctcag gatcgatccc aaatgcattc
    23461 tcatcatata cactgtttgg tccgccagaa agaatgattc cctttggatt catcgctttt
    23521 acttcttctg cagtaatgcg gtggctcaat aattcggaaa agactccaag atcacgaata
    23581 cgtcttgtga tcaattggtt atactgacta ccgtagtcta atacgataat cttttcaacg
    23641 ttcgtcatat cggcaacgtt tgtcaaattt attaccccta tccctttaaa ttttatctca
    23701 aaatagtcaa actattttaa aatgctaata ttttcgcatg aaaatcgaat cgatgatatg
    23761 attttcagtt ttatggagaa ttatatcggc tcttcctcgt gtaggcaaga tatattcctg
    23821 taaatttttc aaattcacat ttttccatac atcttttgcc attttaaagg cttcttcacg
    23881 atctccgata gcaaaacgat aataataatt ctctggattt tggaaagccg tatccagtaa
    23941 cgcaccaaaa cgatccaaat accatttttc gatcagcacg ggatcggcat cgacatagac
    24001 agaaaaatca aaaaagtcgc tgacgtagat ttgctgattc gcaggtaatt gaagcgtatt
    24061 gatcccctca acgatcaaga tatcaggctg ctggatcaat tcgtacttgt ctggaatgat
    24121 atcatacaca tcatgtgagt aaacaggtac ttttatctct tcctgaccag attttacacg
    24181 gttcaagaaa tcgatcagca tctccatatc ataactttca ggaaatcctt tacggtccat
    24241 gattccacgc tcttttaata tacgatttgg ataaagaaat ccgtcagtcg tgatcagctg
    24301 aacgtttctt cgtttgaagg tacgagacaa aatcgtctgc agcagtctgg ctgttgtact
    24361 ttttccaacg gctacacttc cggcgatccc gataataaaa ggcggtactt ctacgtattt
    24421 atgaagaaat aaacctttac tcaagaacaa agattcaaat tctttcatat aaagataaat
    24481 cagatgagca agaggtacat agatatctcg aacatcctgc atggaaatgc ggtcattcaa
    24541 acttttgata ttatctagtt catcttgtgt caaaggtgct tgcccattac gataaaattc
    24601 tcgccattct tctcttgcca cacggtagta gttcattgga tcattcatat tagcctcctg
    24661 cgttctccca tcaatggaac tattttaaca caaaataaac gcaaacccca ccacttaaga
    24721 gagattgccg atctttttgt ataatcttta taatagaaag aaacggagtc ttattcttga
    24781 cttgcgcacg gatacataaa aggatagact gttgtcatga aagaaatgag aaggatggaa
    24841 gacatgacaa atcattacta ttctgaacgc ccagatacgg cgcacgattt tgaacaatgg
    24901 gcttttgagt taaaaggcag aacctttcaa tttgtaacag attctggtgt attttcacgt
    24961 gaaacagtgg attatggttc acgtgtcctg attgatgctt tcgattggga agagttacct
    25021 gatgaaggaa agatcttaga tgtgggatgc gggtatggac cgattgggtt agctttggca
    25081 tttgcgacac agcggtttgt tgaaatggtc gacattaatg aacgagcggt aagtctagcg
    25141 caaggaaacg caaagcgtaa ccaaatcgaa catgttgata tccatcaatc gaatatctat
    25201 gaagcagttc atgaagaaac ctatgcagct atcgtaagca atccgccgat ccgtgctgga
    25261 aaaaaagttg tacatgaaat tttgacaggc gcatatcctc ggttgaagaa gggcggtaca
    25321 ctgacaattg tgatccagaa gaaacaagga gcgccgagtg cgcaaaagaa aatggaagaa
    25381 acatttggta atgcagaaat cgtcacaaaa gataaaggat attatatcat caaaagtgtg
    25441 aaagaataac tagctgaaaa atagtggagc gacgaaagag tggaactggg cgtgcatgta
    25501 cgggtacgta tcagttcttt ttttgttgag aagtttttaa aaacaaagaa ctattttttc
    25561 ttcaaaaaga aatagtagga acagagtcgt tgttttttac gataaaataa ataagataca
    25621 gaacttgtat agaaggctgc caagtcggta gataaaggag gtttttatca aaaaacatac
    25681 tttccttttt tctctattct tttcttgggg gttttggtac actgataggg aatttagata
    25741 gaagggagcc aataggatga agctgaccat cagagatatc gcagaaatgg caggcgtatc
    25801 agtaacaact gtctcacaga ttttgaataa caaaggaagc agatttagtg ataagacaag
    25861 aaaaaaagtg ttgtcgatcg tgaatgaaca tcattataag cccgattatt tcgcttcaaa
    25921 tgtgatcaat cgacattcaa agaccatcgg aatgatcgtc cctgatgtca ctgatttctt
    25981 cttctccaaa ctgatcgaag gtgtagagag ctatttgaat cctttgggct atgtgatcat
    26041 gttatgcaat tctcgtcata gccaagaaaa tgagatcaag tatttacaag agctttccca
    26101 ccgctcagtg gacggaatct tgctggccac accaaatatt ttacctgaga aatatgcatt
    26161 agacagcggt ttttatcaaa aaatgccaat cattttaatc gatcgcggat tgaatcgtcg
    26221 ggataacgga cggcttatcg taaaggaata tgagggcgcc tatcaagctg tttcgctgtt
    26281 tattgaaaat ggccatacga agatcggcat gctgaaggaa accactggat actatcaatt
    26341 agaagaacgt ttcaacggat atcgtcatgc gctgaaagat catggcctgc cttttaatgg
    26401 gaaatttgtt gaacatggag agttgactgt ccaaggtgga tatactgcat caaaaaaatt
    26461 actcaaacat aaagatatca cggctatttt ttgcgggaat gatgccatgg cgatcggatg
    26521 ctatcaggcg atcgatgaat tgggcaaaaa aatcccagaa gatatctcag tcataggatt
    26581 cgatggatta aagctgtcag aatacatgat tccgcaattg acgacagtgc agcagccaag
    26641 ttttgatatt ggattttatg ctgcacgttt cctgatcgat acgatcgaat ttcctcaaag
    26701 aaaagttccg aacaaagtgt tcgaaacaaa attaattatt cgtgagagcg taaaagtatt
    26761 gacaaagggc taactcggcg gtatattgct tatgtaagca tttacaaagg ctagttagtg
    26821 ctttttttat ttttagtaaa ccagtttact aaagtggttt acctttccta aaaataatgt
    26881 ataataccga atgaagacaa ggaggatcag gcaatgcgaa tggtggatct gattgaaaaa
    26941 aagagggatg gaaacgagct gtcgaaagag gaaatcgagt acatcgtcac gaactatacg
    27001 aatggaaaga ttccagatta tcaagtcagt gcattattga tggcaatttt ttatcaagac
    27061 atgacaaatg aagaaatcac gaacttaaca ttggcgattg ctaattctgg tgatgtcatc
    27121 gatttgagtt ctcttgaagg aataaaggta gataagcatt cgacaggtgg cgttggtgac
    27181 acgaccacat tgattttagc ccccctagta gctagtgtcg gagtgacagt ggctaaaatg
    27241 tctggacgcg gtctaggtta cacaggtggt acactagaca agctagaagc aattcccgga
    27301 tttcagatcg agctttcgga tgaagaattt gtacgcattg ttaatgaaag taaagtagcg
    27361 gtaattggtc aatcaggaaa cttggcaccg gcggacaaaa aattgtatgc cttgcgtgac
    27421 gtcacagcga ccgttgattc tcttccgctg attgccagtt cgattatgag taaaaaaatc
    27481 gcggcaggag cagatgcaat cgttttggat gtgaccactg gagacggtgc tttcatgaag
    27541 aacatcgaag atgcaagacg tctggcaaag accatgacga gcattgggaa actggctaac
    27601 cgagaaacag tggcggttat ctcagatatg tcagaacctc ttggcgaagc tatcggaaat
    27661 agtctagaag ttgtcgaggc aatcgaaaca ttacaaggaa atggtccaga agatctagta
    27721 gaaatgtgct acgccttagg aagccaaatg gttgttcttg ctggcaaagc taagacaacc
    27781 gatgaagcaa gaacgttgct tcaagaagct ctggaatcag gtaaagcgtt agcaaaattc
    27841 aaagaaatga tccaaaatca agggggagac ccagcgatcg tggaacatcc agaacgaatt
    27901 ttgactgcac gctacacaat ggagcttcct gctaaacaaa gcggagttgt gtcaaaaatc
    27961 gtggcaaatg aattaggaat tgctgcaatg atgctaggtg ctgggcgtaa aaccaaagaa
    28021 gaagatattg atcacgctgt tggattgaaa ctgcataaaa aaattggtga cactgtgaca
    28081 aaaggtgagt cactattgac gatctatagt aacgacgaag aaatcacttc tgtcattgaa
    28141 ttattatata aaaatattga aattggtgaa tcggcaatga agccaacgtt gattcatgac
    28201 atcatcacag aataaaggaa aaaagcggac tttaccgttt taaagaaaag gggaaaagaa
    28261 atggaactaa accgaatgat cgaccatact attttgaaag cagacgcatc taaagaagct
    28321 gtgatgcaaa ttatcgaaga agcaaaaaaa taccattttt attctgtctg catcaatcca
    28381 gcatgggttg cgctagcgaa agaacaatta caaggtgagc cagtagccgt atgtacagta
    28441 atcgggtttc ctctaggagc aaacacaccc gagacaaaag catttgaaac aacagatgcc
    28501 atcaataacg gtgcagatga agtcgatatg gtcatcaata tcggtgcttt gaaatcaaag
    28561 gatgatcaac aagtccaaaa agatatcgaa gcagttgttg aagcagcaaa agatcgtgcg
    28621 cttgtcaaag ttattattga aacatcgtta ttagatagag aagaaatcat ccgagcttgc
    28681 gaaatagcaa aagctgcagg cgctgatttt gtcaaaacat caactggttt ctcaacaggc
    28741 ggagcaaagg tagaggatgt ccgtttgatg cgtgaaactg taggaccaga aatgggtgtc
    28801 aaagcttccg gcggtatcca taacgaagaa gaagcaatgg caatgatcga agctggtgct
    28861 acaagaatcg gaacaagcgc aggagtagca atcgtatctg gttcaactgg tgaaggctat
    28921 taattttttc aaaggagaag ctcatggcag aactcaaaca agaatggatc aacacagcta
    28981 ttgaagcgtt agataaagcc tatgttcctt attcccattt tccggtaggc gcttgtctcg
    29041 taacggaatc aggcaagatt tatcaaggca tcaacattga gaatgcatca tttggattaa
    29101 cgaattgtgc cgagcgcaca gcttttttca aagcagtatc tgaaggagaa aaaacattta
    29161 cgcatctagt cgtagcgggg cacacccccg atcctatctc tccttgtggt gcatgtcgac
    29221 aagtaatggc agaattctgt tcccctgata tgccggttac gctagtagga gacaatggtg
    29281 tgacgaaggc aacgaccgtt cgtgcactgc tgccttatgc atttactgaa aaagatctat
    29341 aactcatgtt cattcagtca gctgactgtt gaaaaataaa acaattattt taggaggctt
    29401 tacagaaatg aaaaaagcaa aattatttgg tttaggtgct gtcgcactag cagcagggtt
    29461 atttttaggt gcatgcggca acaacggctc tactgattca tccggtggca aaagctcatc
    29521 agacacaaca actgcagcat tgatcacaga cacaggtggt gtagacgacc gttcattcaa
    29581 ccagtcagct tgggaaggac tagaaaaatg ggggaaagat caaggacttt cacgaggaaa
    29641 tgatggcttc caatatttcc aatcttcaaa tgaatcagat tacatcccaa atattgacca
    29701 agcattgaat gctggattca aaacgatttt tggtattggt tataaactaa aaccagcgat
    29761 ccaagaacaa gcaacaaaca atacaggtac gaactttgtt attatcgatg atgtcatcga
    29821 tggattagat aacgttgtat ctgcaacttt caaagacaac gaagcttctt atcttgcagg
    29881 tgttgcagca gcttatacga ctgaaacaaa cgtagtcggc tttatcggcg gtgtaaaagg
    29941 tgaagtaatc gatcgttttg atgctggatt caaagccggt gttgatgcag gtgcgaaaga
    30001 attaggaaaa gaaatcaaag tattgaatca atatgctggt gacttctctg ctccagataa
    30061 aggacgttca attgctcaag gtatgtatgc acaaaacgca gatatcatct tccatgcttc
    30121 aggcggtaca ggtaacggtg tattccaaga agcaaaatca ttgaacgaat caggcgacaa
    30181 aaaagtttgg gttatcggtg ttgaccgcga ccaatcagac gaaggcgaat acacattaaa
    30241 cggcgaaaag aaaaacttca cattgacatc tacactgaaa gcagttggaa cagtagtaga
    30301 agatttggca caaaaatcag cggacggtaa attccctggc ggcgaacaca ctgtttatgg
    30361 attgaaagaa gacggtgttg gtctaacaga aggacaactt tctgacgaag cgaaaaaagc
    30421 agttgatgaa gcaaaagaaa aaatcatttc aggtgacgta aaagttccag aaactcctga
    30481 agaaaactaa aaccatttct atagccttgt tagacacatg tttgacaagg ctatggtttg
    30541 attagaacaa gaattgttca tttatccaag ctgccttgtg acagtttgga taagggaaca
    30601 actccctgaa gtaatgtttg tttcaaaaga agaacgctca ctaagcgtga atcttagtca
    30661 atcgttgccc tagatagaaa tcgttaggat gtgaaaaaaa ggtggttcaa gaaaatattg
    30721 tcatagaaat gcagaatatt accaaagaat ttggaacatt caaggcaaat gacaacatca
    30781 atttacaagt aaaggcagga gaaattcatg cgttgcttgg agaaaacggt gctggcaaat
    30841 ctacattgat gaacgtgctt tccggattat tagagccgac atcagggaaa attttgatgc
    30901 gtgggaaaga agtaaagatc acaagtccga ccaaagccaa ccaattaggg attgggatgg
    30961 tccatcagca ctttatgctt gttgatgcct ttactgtaac agaaaacatc gtgttgggaa
    31021 gcgagcctag tcgcgcaggg atgcttgacc ataaaaaagc acgaaaagag atccaaaaag
    31081 tttctgaaca gtatggattg tcagtcaacc cagatgctta cgttcgtgat atttcagttg
    31141 gaatggaaca acgggtagaa attttaaaaa cactttaccg aggagcagat gtactgattt
    31201 ttgatgagcc gacagctgta ttgacccctc aagaaattga tgaattaatc gtgatcatga
    31261 aggaattagt caaagaaggc aagtcgatca ttttgattac gcataagtta gatgaaatca
    31321 aagcagtagc tgaccgctgt acagttatcc gccgtggaaa aggaatcggt acagtcaacg
    31381 ttaaagacgt aacctcacaa caattagccg atatgatggt tggaagaacg gtttcattca
    31441 aaacgatgaa aaaagaagcg aagcctcaag aagtcgtttt gtctattgaa aatctagtgg
    31501 tgaaagaaaa tcgtggatta gaagccgtga aaaacttgaa cttagaggtt cgtgctggcg
    31561 aagtacttgg tatcgctgga atcgatggaa acgggcagtc ggagttgatc caagctttga
    31621 ctggtttgcg aaaggcagaa agcggacata tcaagctaaa aggggaagac atcactaata
    31681 aaaaaccccg aaaaatcact gaacatggtg taggacacgt gccagaagac cgtcataaat
    31741 acgggttagt cctagatatg acattatctg aaaatatcgc actacaaacc tatcatcaaa
    31801 aaccttacag taaaaacggc atgctgaatt attcagtaat gaatgaacat gccagagaat
    31861 tgatcgaaga atatgatgtt cgaacaacga atgaacttgt tcccgcaaaa gctttatcag
    31921 gcggaaatca gcaaaaagca attatcgctc gtgaagtcga ccgagatcct gatctgttga
    31981 ttgttgcaaa tccaactcgt ggactggatg taggtgcgat cgaatttatt cataaacgtc
    32041 tgatcgaaca aagggacaaa tacaaagcag tgttactgat cagtttcgaa ttagaagaaa
    32101 ttttaaatgt ttcggatcgt attgctgtta tccatgaagg agaaattgtc ggtatcgttg
    32161 atccgaaaga aacatctgaa aatgaattag gtctattgat ggcgggctat accttagaag
    32221 aagcacgaaa agagttagaa aagggggctg gcgcacatga atgatcgcag cgaaaaattc
    32281 cgtaatttat tagtgcctgt actttcagtt gttttaggat tgatcttagg cgcgatattg
    32341 atggctgctt ttggttttca gcccatccaa ggttattctt ctatgctaga tgcagccctt
    32401 ggttcgcaaa gagggatagg tgaaacgtta aggcaagcaa cgccgttgat ttttacagca
    32461 ttaggttttt ctgtagctaa ctcagctggg tttttcaata ttgggctttc tggacaagca
    32521 ctttgcgggt ggatcgtcag tgtctgggtg gcacttgcgt ttccagatct gccaaaagtt
    32581 gttttgcttc cgttatgcgt gatcttaggt gccttagctg gtgcgatggc agcggctgtt
    32641 ccaggtttac ttcgagcatt ttttggaaca agtgaagtga tcgtaacaat catgatgaac
    32701 tatatcttat tatacgtaag cacatttgct ttacatgaag tgatgcctga aagctatcgc
    32761 tcaagtttgg actcttccaa tatgatcagt caaaatgcct cactgcggtt accatggtta
    32821 acacaagctt ttggcggctc tcgcgtaaac tcaggattat ttttagcaat catcgcgctt
    32881 attttcgttt ggctgctgat gaagaaaacg actttaggat ttgaaatccg ttctgttgga
    32941 ttgaatcctt ttgcttctga gtatgcagga atgagtagta aacgtacgat cgttttgtcg
    33001 atggtcattt ctggcgcttt ggcagggctt ggcggtgtgg ttgaaggatt aggaacgtat
    33061 caaaacttct ttgttcaaac gacttcgcta tctattggat ttgacggaat ggctgtttcc
    33121 ttgcttggtt ctggatcagc aatcggtatt cttttatcag cgatcttgtt cagtattttg
    33181 aagatcggtg gacttggcat gcagacagga gcaggtgttc cgtttgagat cgtcaatgta
    33241 tcgattgctt tgattatctt ctttgtcggg atcaacttcc tgattcgttt cgtcatggct
    33301 aaagtcttcc aagggaaaaa acaagaagag atcgttgcga caatagaatc gaaaccaacg
    33361 aatcaaaacc atgaaggggg cgaactataa tgtcgactat cgaattaatt gccttgatcc
    33421 ttacttctac actggtttat tcaacaccgc taattctaac gtcactaggc ggaacttttt
    33481 ctgaacgaag cgggatcgta aacgtagggc tagagggaat catggtcatg ggtgctttta
    33541 gttccatcgt tttcaacttg acgatgagtc catcacttgg ttctatgaca ccatggatcg
    33601 ctattttagt gggtggcgtc gtaggtatcc tattttctct gattcacgca gtagcaacag
    33661 tcagtttgcg tgctgaccat attatcagcg ggacagtaat taatctgatg gcacctgctt
    33721 taggtgtttt cttgatcaaa gcatggtatg gtaaaggtca aactgataac atcacgcaga
    33781 atctggggta tttttctttc ccaggattag cagatattcc ggtcattgga ccaattttct
    33841 ttaaaaatac attcttacct gcttattgtg ctattttgat tgctgtccta gcttgggtga
    33901 tcatcttcaa gacgaaattc ggcttgcgcc tccgttcagt tggtgaaaat cctcaagctg
    33961 ccgacacatt aggtatcaat gtatatgcta tgcgttattc aggcgtactg atttctggct
    34021 tgttaggcgg tatgggcggt gctgtttttg ctcagtcgat ttccggtaac ttttcagctg
    34081 gtacgatcgt tggacaaggg ttcatctcca tggctgctat gatctttggt aagtggaatc
    34141 ctttaggggc aatgggtgcc tcattgttct ttggttttgc tcaaagcttg agtatcattg
    34201 gcgcacaatt accagttatt tcttcgattc cgccagtatt gctgcaaatt gctccatatt
    34261 tgctgacaat cattgtgctg gttgttttct tagggaaagc ttctggtcca aaagcaaacg
    34321 ggaagaacta tatcaaatca aaataatctt ttagcgaata aaaagggtgg gttacgggaa
    34381 gtgtttttcg tctcgccctt tttgttttaa aggcaataaa aataaaaaga aagaaggaat
    34441 aatcatgttt aaacgcgtac atctgatcgt catggattca gtaggaattg gagaagcacc
    34501 agatgccgat aagttcggtg atgttggttc tgatacatta ggacacattg cgaaagaagc
    34561 aggattgaac gttccacatt tagagcagct tggtttagga acgatccgtc ctcttgaagg
    34621 tgtggaatca gtgaaagatc atcaaggcta tgcgacgaaa ttagaagaag tttctgtagg
    34681 gaaagatacg atgacaggcc actgggaaat catgggattg aatatcaaaa ctccatttcg
    34741 tgtgtttcct aatggattcc ctgatgatct gatcaaacaa atcgaagaat tttctggccg
    34801 taaagtcgta tgtaacaaac cttatagcgg aacagctgtt attgacgatt acggtgaaca
    34861 ccaaatgaaa acaggcgatt taattgtata tacttctgcc gatcctgtcc ttcagatcgc
    34921 ggcacatgaa gaaatcattc ctttagaaga attatatcgg atttgccaat tcgttcgtga
    34981 tataacaaaa gatgatccgt atatgattgg ccgaatcatt gcacgtccgt acgtgggtga
    35041 accaggagac ttcacacgaa caagcaatcg ccatgattat gcgttgaatc cattcggaca
    35101 cacagtcctt gattctttga aagaagcagg aaaggacgtg attgctgttg gaaagatcaa
    35161 cgatattttc aacggacaag gaatcactga atctgtccgc acgaaaagca atatggatgg
    35221 cgttgaccag ctgctgaaag ttatgaaaaa cgatttttca ggaatcagct ttaccaattt
    35281 agtagatttt gatgcattat acggtcatcg tcgggatgta gtcggctatg cgcatgcgat
    35341 tgaagaattt gacttacgaa ttccagaatt gcttgaagcg atggaagaag acgacttgct
    35401 aatgattaca gccgatcacg gaaacgatcc gacgtttact ggtaccgatc atacgcgaga
    35461 atatgtaccg ttattggttt acagtaaaaa aatgaaagaa caaggggcat tgcctcaagg
    35521 atattattca gatatttcag caacgattgc tgagaacttt agtgtttctt cgactgaaaa
    35581 tggcgaaagc ttcttgaaat tattaaaata atctttttaa ataggagaaa gcaaatgacc
    35641 aagttaagcg agatgttaca agaaacgacc cagtttatcc ttgataaagg agtaaaagaa
    35701 attgattttg gtttgattct aggttcagga ttaggtgaat tagcagatga aatcgaagat
    35761 gctgtaatga tttcttatga tgagatcccg ttctttcctg tttcgacagt agttgggcat
    35821 gcaggaaagc tagtttatgg gtctctggca ggcaagaaag tgttagccat gcaagggaga
    35881 ttccactact atgaaggtca ttccatgcaa acagtgacct atccagtacg tgtgatggcc
    35941 ggactagggg cccattcagt cattgtgact aatgcatgtg gtggtgtcaa cgaatcattt
    36001 gtaccaggag atttgatgct gattaccgat catatcaatt ttactggtga aaatcctttg
    36061 atcggtccga atgaagatgc aatgggccct agatttccag atatgagtca agcttatacg
    36121 cctgactatc aagcaacagc aaaagcagca gcagaaaaac taggtttgga tcttaaagaa
    36181 ggcgtatata tgggctattc tggaccaact tatgaaacgc ctgcggagat ccgaatgtct
    36241 cggacaatag gagccgatgc agtagggatg tcgactgttc cagaagtcat cgtagcagct
    36301 cacagcggat taaaagtgtt aggaatctct tgtattacca acttagcagc aggtatgcaa
    36361 gcgaatctga gccatgaaga agttgtagaa acaactcaga gagtcaaaca atcttttaaa
    36421 gcattggtta aagaaacatt gacattattg taataggagg aacaataaaa tgagtgtgca
    36481 tattgaagcg aaagaaggcg agatcgccga taagatttta cttccgggag atcctttgcg
    36541 agctaaatat attgcggaga cttttttgga agatccagtt tgttacaatc aggtacgcgg
    36601 tatgttaggc tttaccggca aatataaagg agaacgtatt tctgttcaag gaacaggaat
    36661 gggaatgcca tcagccacca tctatgccca tgaattgatc cagtcgtatg gtgtaaagaa
    36721 attgattcga gtaggtacat gcggtgcatt gtcaaaagac gtccatgttc gtgatttagt
    36781 actagcacaa ggtgcagcga ccagttcttc gatgatcgaa aaaaatttcc aagcctttca
    36841 ttttcctcca atcagtgatt tcaatctatt actgaaagca tatgagatag ctaaagaaaa
    36901 gggctatacg gttcatgtag gaaatgttct ttcggaagat tctttctaca aagatgattt
    36961 gacagagacg ttccaattag ctgaacttgg cgttttagga gtggaaatgg aagcagcggc
    37021 tctttattac ttaggcgcga aataccatgt gcagacatta agtttgatga ccgttagcga
    37081 ccatttgatc accggtgaag aaacaacagc tgcagaacgt caatctacgt tcaatgaaat
    37141 gatcgaagta ggattggaaa cagcgatagc agaataagaa ggaaatgaaa aagctgccct
    37201 gcattaagta ataagaacat ccaagcaaaa atagctcctc atgtttttga cttggctgga
    37261 cttattattg caaatgtaag cttttgaaca ccgtttacca agaggttgtg aatctgccgt
    37321 ttaactctga gtcacaagga acaatttcaa aaaacagctt ttcatgtttg atgaatattg
    37381 tgacttgtga ccgagaagtt ggcaggagaa aaccgtttat acgaaaaaag ggactgtgac
    37441 aaatcgtgtc acagtccctt ttttatagtg ttttttatag gtagtatttt ttagcaactg
    37501 ttaagtcatc atttaattca taaacaagtg gttgacctgt tggaatttca agatccatga
    37561 tgtcttcgtc agagatacct tcgatatgtt tagctagggc gcgtaatgag ttaccatgtg
    37621 cagctactaa aacagttttg ttgtctagta atgctggagc aatttcatct tgccagaatg
    37681 gcaaagcgcg ttctaatgtc actttcaagt tttctccacc aggaatatcg cgtttgtcta
    37741 acattgcgta acgacggtca tttgctgcag aaccttcgtc agtttcttcc attaatggag
    37801 gaagagtatc gtaagaacga cgccagatgt gcacttgttc gtcgccgtat ttttcagctg
    37861 tttctttttt gttcaaacct tgtaatttac catagtgacg ttcgtttaag cgccatgatt
    37921 tgatttgtgg tacccaaagt tgatctgaat attctaagat caagttacat gttttgattg
    37981 cacgagttaa aacagaagtg taagcaacat caaattcgat tccagcttct ttgattttgc
    38041 gtccgccttc ttttgcttct tcgattcctt ctggtgctag atttacatca gcccaaccag
    38101 taaattggtt caatgcattc cattcactaa gaccgtgacg agaaaaaact aattttggca
    38161 tgtttagctc tccttttaag ataggtttat atttctgaaa ttttcagttc tgttttattg
    38221 tacaattttt tggaagagat ttccatcgaa aaattagata agattctatg agaaaacaag
    38281 tagagaatat aaaaaaacga acagtgccca cgcaactgtt cgtttttagg tattagatgc
    38341 ataattgctc gatttctttt tcaggtaaat tgatatattt ataacatgtt ccaactgaaa
    38401 caccgcattt tgaagaaata aattggatcg tttctttttt ttcataatag agacgtcgga
    38461 tttttttgat cgtttttgca tcgatttttg gtcttccgcc gatttttcct tttttacgag
    38521 cttcatctaa tccaactaat gtacgttctt tgatcaatgc gcactccatg tttgctaggt
    38581 tttccattaa ttggaaatag atttttccca tttcgcgcgt atcgattcct tcatcaagac
    38641 taatcaagtg cagcccgcga tctttgaata attgcgtgag ttctgttaat tgccgcgtag
    38701 atttgcctaa tcgatgaagt tggcaaatga ctagtgcatc gccttgttgc atgtcagcga
    38761 tcactgactc caaatgaaca gcagtagaat cattttgttc cacttcatat gtctcatgga
    38821 aaatttcttg acaaccaaag tcagataatt gatcaacctg agttgttaaa tcaacgtcat
    38881 ttatggttgt gcgtgcataa ccaataattt tcatggtgat tcctttctag cagtgatttt
    38941 ctaactggat ataacagtaa aaatgtagca taaagtacgt caaaaagata gttttttcgc
    39001 aaattttccg ctgtcttttt ttattggatg atcaagcagt ttttctttat ttacgacgga
    39061 ttgcgtcaag aatctcaacg cctttttctg agccgacaac tactttagaa accatgttta
    39121 ggaaaagccc atgttctact accccaacaa gttcatctaa ataggtagct aagctttctg
    39181 gctgttcgat gacttctaga tgcagatcaa tgatgtaatg accaccatct gtggttaaga
    39241 cttctccgtt ttcgtctgta cgcaagacgg gttggaatct tttttcttca aaaatatgaa
    39301 gtagctgttg ggagccataa gggatcactt caactgggag tgggaacttc ccaagtttat
    39361 cgactaattt agaagaatca acgatccaaa tcgtttcttt tgagtacgta gcgactattt
    39421 tctcgaaaag caaagcagcg ccgccgcctt tgatcccttg aaaatcagca ctgatttcat
    39481 cagcaccgtc tattgtcaaa tcgactacgg ggacttcatc aatactcttt aacggtattc
    39541 ctaatttttc cgcttgttct tttgtcgcat ttgaagtagt aactcctgtg atacgtaaac
    39601 cttcttcacg catacggcga ccaatctctt ctaccatata ataggcggtt gaaccggtcc
    39661 cgagacctac gatcatcccg tcctttacga atttcgcggc ttcaatgcca gctaattgtt
    39721 ttaaattcat ctttgcgtcc accttttttt agtttgagca tcgtgctttc ctcactattt
    39781 tagcgtgatt tacggtaaaa agataccatt cttttttatt ccaataaagc tttttcaaaa
    39841 aaaattgcat ctcttgttga catgtttttt cattcgtgat attctaacaa aggtgcttta
    39901 tctacaggtt tctgtgaaga aacgtgctga ctgtttatca aagcatattt gataaggatg
    39961 cagacattgc atttattttt tatcacaaaa aaagaaccac ctggatgtgt ggaactagac
    40021 gcaaatcgtg ggaaggagga aacaaggaat gcctacaatt aaccaattag tacgtaaacc
    40081 tcgtaaatca aaggtggaaa aatctaattc acctgctttg aacaaaggat ataacagctt
    40141 taagaaaact caaactaacg taaactcacc tcaaaaacgt ggggtagcaa ctcgtgtggg
    40201 tacaatgaca cctaaaaaac cgaactcagc tttacgtaaa tatgcacgtg ttcgtttgtc
    40261 aaacttaatt gaagttactg cttatatccc agggattggt cataacttac aagaacacag
    40321 tgttgtatta ttacgcggtg gtcgtgtaaa agacttacca ggggtacgtt accatatcgt
    40381 tcgcggtgct ttagatactg ctggtgttaa cgaccgtaaa caaagccgtt ctaaatacgg
    40441 aactaaaaaa cctaaagctt aattttaatt attaaacaaa tgaaacttgc ttctactata
    40501 tagaagtaat tactatgaac aatatttcgg aaggaggagt tacggatgcc acgtaaaggt
    40561 cctgttgcaa aacgtgatgt tttaccagat cctatttata actcaaaatt agtaactcgc
    40621 ttgatcaacc gtgtaatggt tgacggaaaa cgcgggattg cagctaacat tatctataat
    40681 gcctttgact tgatcaaaga atctacaggt aacgatccat tagaagtgtt tgaacaagca
    40741 atgaaaaacg ttcaacctgt tcttgaagtt aaagcacgtc gtgttggggg ttcaaactac
    40801 caagtaccag ttgaagttcg ccctgaacgc cgcgttactc taggtcttcg ttgggtagta
    40861 aactacgctc gcttgcgcgg tgaacacaca atggaagaac gcttagcaaa agaaatcatg
    40921 gatgctgcaa acaacacagg tgcttctgtt aaaaaacgtg aagacactca taaaatggct
    40981 gatgccaacc gtgcgtttgc tcactatcgc tggtaagatt ctctctgttt ggtcggcttt
    41041 tataagtcga cctcagatag tgtccttatt tttagcaact agatagtaaa gagaggagaa
    41101 acaaggagaa tgaccagaga attttcttta caaaacactc gtaatatcgg tatcatggcc
    41161 cacatcgatg ctggtaaaac gactgctact gaacgtatct tgtactatac tggtaaaatc
    41221 cataaaattg gtgaaactca tgaaggagct tcacaaatgg actggatgga acaagaacaa
    41281 gaacgtggta ttacgatcac ttctgctgct actacagcac aatggaaggg tcaccgaatc
    41341 aacatcatcg acacaccagg acacgtagac ttcacagttg aagttgaacg ttcattgcgt
    41401 gtacttgatg gtgctgtaac tgttcttgat gcacaatcag gtgttgaacc tcaaactgaa
    41461 acagtttggc gtcaagcaac aacttatggt gtacctcgta tcgtatttgc aaacaaaatg
    41521 gacaagatcg gtgctgactt cttatattca gtatcaactt tacatgaccg tttgcaagca
    41581 aacgctcacc caatccaatt accaattggt gcggaagacg acttcacagg aattatcgac
    41641 cttgtaacaa tgaaggctga aatgtataca aacgatcttg gaacagagat cgaagaaaca
    41701 gaaattcctg aagaataccg cgaattagct gaagaatggc gcgaaaaatt ggttgaagct
    41761 gtagctgaaa ctgatgaaga acttactttg aaatacttag aaggtgaaga aatcactgaa
    41821 gctgagttaa aagaaggtat ccgccgcgca acagttaacg tagaattcta cccagtacta
    41881 tgtggttcag catttaagaa caaaggggtt caattactat tggacgctgt tcttgattac
    41941 ttgccatcac cgttagatat cccagctatc aaagggattg accctaaaac tgatgaagaa
    42001 gtagaacgtc ctgcagacga cagcgctcct ttctcagctt tagcatttaa agttatgact
    42061 gacccattcg taggtcgttt aactttcttc cgtgtgtact ctggtgtttt acaatcaggt
    42121 tcatacgtac aaaacgcaac aaaaggcaaa cgtgaacgtg ttggtcgtat cctacagatg
    42181 catgccaact ctcgttcaga aatctctgaa gtttacgctg gagatatcgc tgctgctgtt
    42241 ggtttgaaag acacaactac tggggacaca ctatgtgatg aaaagagtct agttattctt
    42301 gaatccatgg aattcccaga accagttatc caagtcgcta ttgaacctaa atcaaaagct
    42361 gaccaagata aaatgggtgt ggctttacaa aaactatctg aagaagatcc tactttccgt
    42421 gctgaaacaa acgtggaaac aggcgaaaca atcatcgctg gtatgggtga acttcactta
    42481 gatatcatcg ttgaccgtat gcgtcgtgaa ttcaaagttg aagctaacgt aggtgcgcct
    42541 caagtatctt accgtgaaac tttccgtgct ggcactcaag ccgaaggtaa gtttgtacgt
    42601 cagtctggtg gtaaaggtca atacggtcac gtatggattg aatttacacc aaatgaagaa
    42661 ggtgctggtt tcgaatttga aaatgcgatc gtcggtgggg ttgttcctcg tgaatacatt
    42721 ccagctgttg aaactggttt gaaagatgct atggaaaatg gtgtcttagc tggctatcca
    42781 ttagtagata tcaaagctaa actttacgat ggttcatacc atgatgtcga ttcaaatgaa
    42841 actgccttcc gtgttgctgc ttctatggca ttacgtgcag cagctaagaa agctaatcca
    42901 gtaatccttg aaccaatcat ggctgtagaa gttgttatcc ctgaagatta tttaggtgat
    42961 gttatgggtc acgtaactgc tcgtcgtgga cgtgttgaag gtatggaagc tcgcgctggc
    43021 ggccaacaag ttgttcgtgc gatggttcca cttgctgaaa tgtttggtta tgctacaact
    43081 cttcgttctg ctactcaagg tcgtggtaca tttacaatga catttgacca ctacgaagat
    43141 gtaccaaaat cagtacaaga agaaatcatt aagaaaaacg gcggaaaagc tgaataattt
    43201 cttaaaaccg gatagtcctg caaagagatt atccaaagag actatatttt taatatagtt
    43261 tcgtgtaaaa taattatcga tgatatgggc atgtggtgta ccttgtgtac atcatatacc
    43321 tatcagacaa ataaaaaata tattgtattt ttaggaggac attttaaaat ggcaaaagaa
    43381 aaatttgacc gttctaaacc acacgttaac attggtacta tcggacacgt tgaccatggt
    43441 aaaactacat taacagctgc aatcacaact gtactatcta agaaaaacgg cggccaagct
    43501 atggcttacg atcaaatcga tggtgctcca gaagaacgcg aacgcggaat cacaatctca
    43561 acagctcacg ttgagtatga aacagataca cgccactacg ctcacgttga ctgcccagga
    43621 cacgcggatt acgttaaaaa catgatcact ggtgctgctc aaatggacgg agctatcttg
    43681 gtagtttctg ctgctgacgg cccaatgcct caaactcgtg aacacatcct attgtctcgt
    43741 caagttggtg ttccttacat cgttgtattc ttgaacaaag tagacatggt tgatgacgaa
    43801 gaattactag aattagttga aatggaagtt cgtgacctat taacagaata cgaattccct
    43861 ggtgacgatg ttcctgtagt tgctggatca gctttgaaag ctctagaagg cgacgcttca
    43921 tacgaagaaa aaattcttga attaatggct gcagttgacg aatacatccc aactccagaa
    43981 cgtgacaacg acaaaccatt catgatgcca gttgaagacg tgttctcaat tactggacgt
    44041 ggtactgttg ctacaggtcg tgttgaacgt ggacaagttc gcgttggtga cgaagttgaa
    44101 gttgttggta ttgctgaaga aacttcaaaa acaacagtta ctggtgttga aatgttccgt
    44161 aaattgttag actacgctga agctggagac aacattggtg ctttactacg tggtgttgca
    44221 cgtgaagaca tccaacgtgg acaagtttta gctaaaccag gtacaatcac acctcataca
    44281 aaattctctg cagaagtata cgtgttgaca aaagaagaag gtggacgtca tactccattc
    44341 ttcactaact accgtccaca attctacttc cgtacaactg acgtaacagg tgttgttgaa
    44401 ttaccagaag gaactgaaat ggttatgcct ggcgacaacg taacaatgga agttgaatta
    44461 atccacccaa tcgctatcga aaacggtact aaattctcaa tccgtgaagg cggacgtaca
    44521 gttggtgccg gtgtcgttac agaaatcaaa gcttaattca cttaagtttt aaagtaaagc
    44581 aacatttatt cggacgtaat cgctcggaac gaaggtctta ggatctttgt tccgagcttt
    44641 tttatttatt gcaggatcag gaaaaaagac aggagtatta taaatagaag aaacacgaaa
    44701 taaaagagtc agtattttct aaatgaaact ttatgaaaac aaaatgtttt ttacaagaaa
    44761 aagccttgct ttgtgagttt atatatatta taatgacaaa ggtgcgttta ctttagtgaa
    44821 ttgcacagac gtaatcagaa tgatttcgtc ggctaagaaa cgagaggttg cgacacgccc
    44881 ggacgctttg ccacgaacga gcgtgacgga aattttcgtg gagctatgtc tacttttcaa
    44941 aataggcgaa ggagggaaca agatggcaaa acaaaaaatt cgtatccgtt taaaagcgta
    45001 tgaacaccgt attttagatc aatcagcgga taaaatcgtg gaaactgcaa aaagaactgg
    45061 agctagcgtg tctggtccaa ttccattacc aactgaacgc agtctttaca caatcatccg
    45121 tgcgactcat aaatacaaag attcacgcga acaattcgaa atgcgtacac acaaacgtct
    45181 tatcgacatt gtgaacccaa caccaaaaac tgttgatgct ttgatgaagc tagacttacc
    45241 atctggtgta aacatcgaaa tcaaattata aaactaaaac aaaaataatg gaggtgtact
    45301 catgaccaaa ggaatcttag ggaaaaaagt gggaatgaca caaatcttca ctgaatctgg
    45361 tgaattaatt ccagtaactg ttgtagaagc tactccaaac gtagtactac aagtgaaaac
    45421 aatggaaacg gatggctacg aagctattca agttggttac caagatatgc gtgaagtttt
    45481 atcaaacaaa cctgcgaaag gtcatgttgc aaaagcaaac acggctccta agcgcttcat
    45541 tcgtgaattc aaaaatgttg agctaggaga atatgaagta ggaaaagaaa ttacagtaga
    45601 tgttttccaa gcaggagaca ttattgatgt aacaggtact acgaaaggta aaggattcca
    45661 aggggttatc aaacgccacg gacaaagccg cggaccaatg gctcacggtt ctcgttacca
    45721 tcgtcgtcct gggtcaatgg gtccagttgc acctaaccgt gtatttaaaa acaaacgtct
    45781 tgctggccgt atgggtggca accgcgtaac tatccaaaac ttggaagttg tacgtgtcga
    45841 tgcagaaaga aatgttatct tgatcaaagg taatgttcct ggagctaaaa aatctttaat
    45901 tactatcaaa tcagctgtga aagctaaata attgtaggaa gaaaggagga actaaggaat
    45961 gccgaatgta gcattattca aacaagatgg aagccaaaac ggtgaaatca cacttaacga
    46021 agaaatcttc ggaattgaac ctaatgaaag tgttgtttac gatgcaatcg taatgcaacg
    46081 tgcgtcatta agacaaggaa cacacgcggt taaaaaccgt agcgctgttc gcggcggcgg
    46141 acgtaaacca tggcgtcaaa aaggaacagg tcgtgcacgt caaggatcta tccgctcacc
    46201 acaatggcgt ggaggtggcg tagtctttgg accaacacca cgttcttaca gctacaaact
    46261 tcctaaaaaa gttcgtcgtt tagcaatgaa atctgtattg tcagaaaaag ttgctgaaaa
    46321 caacttggta gcaatcgaag gcttgaactt cgacgcacca aaaacaaaag aattcaaaca
    46381 agttcttgct aacttatcta tcgactctaa agtattggtt gttctagaaa aaggtaacga
    46441 ctttgctgct ttatcagcac gtaacttacc aaacgtttct gtagtaactt ctgataatgt
    46501 gagtgtgcta gacgttgtat caaatacaaa agtgttagca acacaaactg ctcttactca
    46561 aattgaggag gtgcttgcat aatgaactta ctagacgtaa tcaaacgccc agtgatcact
    46621 gaaaaatcaa tgcttgccat ggatgacaag aaatacactt ttgaagtgga cactcgcgca
    46681 aacaaaactt tagtaaaaca agcggtagaa gctgcttttg acgttaaagt caaaaacgtg
    46741 aacatcgtga acgtacgtgc gaaattcaaa cgtatgggca aatatgcagg atatacaaaa
    46801 aaacgtcgca aagcgatcgt tacattgact gaagattcaa aagaaatcca attattcgaa
    46861 gctgctgaat aagcactaat agataactca ttaaattagg agggaaaaac gtggcgatta
    46921 aaaagtacaa acctacctca aatggtcgtc gtaacatgac aggttctgat tttgctgaaa
    46981 tcacaacatc aacacctgaa aaatcattgt tacaaccatt gaaaaaccat gctggacgta
    47041 acaacaacgg ccgcatcact gtacgtcatc aaggtggcgg acacaaacgc caatatcgcg
    47101 tgatcgactt caaacgtaac aaagataacg ttgttgcaac tgttcaaacg atcgaatatg
    47161 atccaaaccg ttcagctaac atcgcgttag tacactatga agatggagtg aaagcttaca
    47221 tcttagcacc taaaggacta gaagtgggta tgaaacttgt ttcaggtcca gaagcagata
    47281 tcaaagtcgg aaatgctctt ccattagaaa acattccagt tggtactgtt atccacaaca
    47341 ttgaaatgaa acctggtaaa ggtggacaat tgatccgttc tgctggtaca agtgctcaag
    47401 tacttggtaa agaaggcaaa tacgtattga tccgcttgaa ctctggtgaa gttcgtatga
    47461 tcttagctgc atgccgtgct acaatcggtt ctgtaggtaa cgaacaacac gaattaatca
    47521 acatcggtaa agctggacgc tctcgttgga tgcgtaaacg cccaactgta cgtggtagcg
    47581 taatgaaccc taatgatcac ccacacggtg gtggtgaagg taaagctcct atcggacgta
    47641 aagcaccagt ttctccttgg ggtcaaccag ctcttggtta caaaactcgt aacaaaaaag
    47701 ctaaatcaga caaacttatt gttcgtcgtc gcaaaaataa ataattactt tgaccatgtg
    47761 tcgcacattt tgagaggagg ttcaccatgg gtcgtagttt aaagaaagga ccttttgtcg
    47821 atgagcattt aatgaaaaaa gttgaagctc aagcaggggt tgaaaagaaa aaagttatca
    47881 aaacttggtc acgccgttca acagttttcc caagttttgt tggatatacc atcgcagttt
    47941 atgatggacg taaacatgta ccagtttaca tccaagaaga catggtagga cacaaattag
    48001 gtgaatttgc acctacaaga acttatcgtg gacatgctgc tgacgataag aaaacgaaac
    48061 gctaatttga ggggaggata aatccaaatg gcagaacaaa tcacatcagc taaagcaact
    48121 gcaaaaacag ttcgcacttc acctcgaaaa gcccgtttag taattgacct tatcagaggt
    48181 aaaagtgtcg cagatgcaat ttcaatcttg aaattcacac caaacaaatc tgctggaatc
    48241 attgaaaaag tattgatgtc agcagttgcg aatgcagaaa ataactttga cttagatgtt
    48301 gaaaacttgg tagtaagcga agcttttgtt aacgaaggac ctacaatgaa acgtttccgt
    48361 cctcgtgcaa aaggatcagc ttctccaatc aacaaacgta caagtcatat cacggtagtc
    48421 gtatcagaaa aataaggagg gataatcagt gggtcaaaaa gtacatccaa ttggaatgcg
    48481 tgtaggcatc atccgcgact gggatgctaa atggtatgct gaaaaagagt atgctgagtt
    48541 cttacacgaa gatttaagaa tccgtaaatt tatttcaact aaacttgctg atgctgctgt
    48601 atcaacagtt gaaatcgaac gcgcaacagg tcgcgtaaac atttcaattc acacagctaa
    48661 accaggtatg gttattggta aaggcggttc tgaagtcgaa agcctaagaa aagaattaaa
    48721 caaattaact ggtaaaagaa tccatatcaa tatcgtggaa atcaaaaaac cagatctaga
    48781 tgcaaaatta gtaggtgaag gaatcgcacg tcaattagaa aaccgtgttg ctttccgtcg
    48841 cgctcaaaaa caagccatcc aacgctcaat gcgtgctggc gctcaaggga tcaaaactca
    48901 agtatctggt cgtctaaacg gagcagatat cgctcgttca gaaggatact cagaaggaac
    48961 tgttcctctt catactttac gtgcggacat tgattacgca tgggaagaag cagatacaac
    49021 atacggaaaa ctaggagtta aagtgtggat ctatcgtgga gaaattcttc caactaaaaa
    49081 aaacactgag aaaggaggga aataatcatg ttagtaccta aacgtgtaaa acaccgtcgt
    49141 gaattccgcg gaaaaatgcg cggggaagct aaaggcggaa aagaagtagc attcggtgaa
    49201 tacggtttgc aagctgttga ttcacattgg atcacaaacc gccaaatcga agctgctcgt
    49261 atcgcaatga ctcgttacat gaaacgtggt gggaaagtat ggattaaaat tttccctcac
    49321 aaatcttata ctgccaaagc aattggggta cgtatgggtt ctggtaaagg ggcacctgaa
    49381 ggatgggttg caccagtaaa acgtggtaaa atcatgtttg aaatcgcagg cgttcctgaa
    49441 gaagtagctc gtgaagcgtt acgtctagct tctcacaaat taccaatgaa aactaagatc
    49501 gtaaaacgtg aggaaatggg tggtgaatcg aatgaaggtt aaagaaatca gagaattaac
    49561 cactgccgaa atgcttgatc aagaaaaaca attaaaagaa gaattgttta atcttagatt
    49621 ccaattagca acaggtcaat tagaaaacac tgcacgtatt aaagaagtac gtaaatcgat
    49681 tgcacgcatc aaaactgtgt tgcgtgaaca agctaagtaa ttatggaagg aggccattaa
    49741 gcgtatgact gaaggaagaa atcaacgcaa agtttatcaa ggtcgcgtgg tttcagacaa
    49801 aatggataaa acaattaccg ttgctgtcga aacaaagaaa aaccacccta tctatggcaa
    49861 acgcatgaac tattctaaga aatacaaagt gcatgatgaa aacaacacag caaaagttgg
    49921 cgacatcgtg agaattatgg aaactcgtcc attatcagct acaaaacgtt tccgtttgtt
    49981 ggaagtagtc gaagaagcag ttattatcta ataacacgag attttcctat atagattgaa
    50041 tgcaaaatct gaaaggagga tacacaacgt gatccaagca gaaagtcgtt taaaagtcgc
    50101 tgataactca ggcgcacgtg aaattttgac gatcaaagtc cttggtggat ctggtcgtaa
    50161 aactgctaac atcggtgatg tgatcgttgc tacggttaaa caagcaacgc caggtggggt
    50221 tgtcaaaaaa ggtgacgtcg ttaaagccgt tatcgttcga acaaaatcag gagctcgtcg
    50281 tacagacggt tcatatatta aatttgatga aaatgctgca gtgattattc gtgatgataa
    50341 aagccctcgt ggaacacgta tctttgggcc agttgcacgt gaactacgtg aaaacaactt
    50401 catgaagatc gtttcactag caccagaagt tttataatct tgagacactt atcaaaggag
    50461 gtgcgaaaca gttatgtttg ttaaaaaagg cgataaagtt aaagttatca ctggaaaaga
    50521 caaaaacaaa gaaggcgttg tactagcagc gttcccgaaa aaagataaag ttattgtcga
    50581 aggtgtaaat gtcgttaaaa aacaccaaaa accttctcaa gctgctcctc aaggtggaat
    50641 tgttgagatg gaagcgccaa ttcatgtttc taacgtgatg gtggttgact ctactggtgt
    50701 agctggccga gttggctaca aagaagtaga cggcaaaaaa gtccgtgttt ctaaaaaaac
    50761 cggtgaagtt ttagataaat aaaagtttaa ggaaggaggg tcttactgaa tgaaccgcct
    50821 aaaagaaaaa tatcttaaag aagtaactcc atcattgatg gaaaaattta actatagctc
    50881 tgttatgcaa acacctaaag ttgaaaaaat cgtcatcaac atgggtgttg gtgatgcggt
    50941 atcaaacgct aaaaacttag ataaagcagt tgaagaatta actttgatca ctggtcaaaa
    51001 accaatgatt acaaaagcta aaaaatcaat cgctggattc cgtttacgtg aaggaatgcc
    51061 aattggtgca aaagttacat tgcgcggaga aagaatgtac gaattcttag acaaattggt
    51121 ttctgtttca ctaccacgtg tacgtgactt ccatggtgta agtaaaaaag cctttgacgg
    51181 tcgtggaaac tatactttag gtattaaaga acaattgatc ttcccagaag tagattatga
    51241 tttagtagat aaagtacgtg gtatggacat cgttattgta acaacagcaa actctgatga
    51301 agaatctcgt gagttgttga cacaattagg catgccattc caaaaataat taaaggaggc
    51361 gaactacgtg gctaaaaaat caatgattgc taaaaacaaa cgtcctgcaa aattttcaac
    51421 acaagcttat actcgttgcg aacgttgcgg acgtccacat tcagtttatc gtaagttcca
    51481 tctttgccgt atttgcttcc gcgaacttgc ctataaaggt caaattcccg gcgtgaagaa
    51541 agctagctgg taaaaagtaa attcgcataa gaaggaggta aaagatcaat ggtcatgaca
    51601 gatccaattg cagattttct aactcgtatc cgtaacgcaa acatggttaa acatgagtct
    51661 ttagaagtac ctgcatcaaa aattaaacgt gacatcgctg aaatcttgaa acgtgaaggt
    51721 ttcgttcgtg atgttgaata catcgaagat gacaaacaag gcgtgatccg tgttttccta
    51781 aaatttggta aaaacggcga acgtgttatc acaaacttaa aacgtatctc taaaccaggt
    51841 ttgcgtgctt atgtcaaagc tgacgaagta ccaaaagtat tgaacggttt aggtatcgca
    51901 atcatttcga cttctgaagg tgttgtcact gataaagaag ctcgtgaaaa aaatatcggc
    51961 ggcgaagtta tcgcttacgt atggtaatca agtagaatct acaaggaggt gtctttaagt
    52021 gagccgtatc ggaaataaag tcgttgttat ccctgaagga gtaacagtta ctcaagacgg
    52081 aaacaacgtt acagttaaag gaccaaaagg tgaattgact cgtacttttt cagcagatat
    52141 caaaatgaat atcgaaggaa acgaagtaac tttcactcgt ccaaacgaca gtaaagaaat
    52201 gaaaacaatt catggaacaa ctcgtgcgaa cttcaacaac atggttgtag gtgtcagcga
    52261 aggtttccaa aaagcgttag aactaatcgg ggttgggtac cgtgcacaat tacaaggatc
    52321 aaaacttgta ttgaacgttg gttactcaca tccagtagaa atcacaccac cagctggagt
    52381 aactgttgaa gtaccagcta acacacaagt aattgttaaa ggtgcgaaca aagaagaagt
    52441 tggcgaatta gctgcaaaca ttcgtggaac tcgtcctcca gaaccttata aaggtaaagg
    52501 tattcgttat gttggcgaat atgtacgccg taaagaaggt aaaactggta aataatcgtt
    52561 tagaaaaatt gcatagaagc cagcagcagg aaaaaggcat ttggctgaag tttaccttca
    52621 aaaaaataca tttttacttg tgccgcagct tctatttttc gaaacgtatt tactgcttga
    52681 aatagtagta caataaaaat aaagaggtga caattgtgat tacaaaacca gataagaaca
    52741 aaacacgtca aaagagacat cgtcgtgtac gtaacaatat ctctggtact gctgagcgcc
    52801 cacgcttgaa cgtttttcgt tctaacaaaa acatctacgc tcaaattatt gatgacgtag
    52861 cgggtgtaac gctagcaagt gcctctacct tggataaaga aatttcaggt ggaacaaaaa
    52921 cagaagcagc acaagctgtc ggtaaactag ttgctgaacg tgcagctgaa aaaggcatta
    52981 aagtagtagt ctttgaccgt ggtggatacc tttaccatgg ccgtgtgcaa gctttagctg
    53041 aagctgctcg cgaaaatgga ctagaatttt agaagaagga ggaataccat tcatggttta
    53101 tatcgatcca aaacatttgg aattagaaga ccgcgttgtt gcaattaacc gtgtaacaaa
    53161 agttgttaaa ggtggacgtc gtctacgttt tgctgcttta gttgttgtcg gtgacaaaaa
    53221 cggacacgta gggtttggta caggtaaagc tcaagaagtt cctgaagcaa tccgtaaagc
    53281 aattgaagat gcgaagaaaa acttagttga agtacctatg gttggttcaa caatcccaca
    53341 cgaagtaatc ggtgctttta gtggtggtag aatcctaatg aaacctgctg tagaaggttc
    53401 tggggttgct gctggtggac cagttcgtgc cgtattagaa ttagctgggg tagcagatat
    53461 cacttctaaa tctttaggct caaatacacc aatcaacgtt gttcgcgcaa cagttgaagg
    53521 tttgaaacaa ttgaaacgtg cagaagaagt tgcagaactt cgcggcaaat cagttgaaga
    53581 attaatcgga taaggaggac aacaataatg gctgaattaa aagttacttt aaaacgcagt
    53641 attatcggac gtcctcaaaa ccaacgcgat acagttaaag cgttaggtct tacaaagatt
    53701 aacagttcag tggttaagcc ttctaatgaa gcaattaaag gcatgatcaa tactgtttct
    53761 cacctagtgg acgttgaaga aatttaattt agaaaaatca taactagaac attaaggagg
    53821 tgccaaacct atgaaacttc atgaattaaa acctgctgaa ggttcacgcc aagtacgtaa
    53881 ccgtgttggt cgtggtactt catctggtaa cggaaaaact gccggacgcg gacaaaaagg
    53941 acaaaaagct cgttcaggcg gcggtgtgcg tttaggattt gaagggggac aaacaccatt
    54001 gttccgtcgt ttaccaaaac gaggattcac aaacgtgaac cgtaaagact atgcagtcat
    54061 taatcttgat gtattgaacc gctttgaaga cggagctgaa gtaactcctg ttgctttagt
    54121 tgaagctgga atcgtgaaaa acgaaaaagc tggaatcaaa gtattagcta atggggaact
    54181 aaacaagaaa ttaactgtga aagcagcaaa attctctaaa gcagctcaag aagcaattga
    54241 agcggctggt ggatcaatcg aggtgatcta atgtttagac tattaaaaga tgcttttaaa
    54301 gtaaaagaca ttagatcgaa aatcctattt actgtatttg tgttgtttgt atttcgccta
    54361 ggtgcacata ttactgtacc aggcgtaaat gctgcttcat tgcaaaacct ttcttctttg
    54421 ccatttttca acatgttgaa cttggtaagt ggtagtgcga tgcaaaactt ttccattttc
    54481 tcaatggggg tttcaccata cattactgct tctatcgtca ttcagcttct tcaaatggac
    54541 atcgtgcctc gatttgttga atggtcgaaa caaggggaag ttggtcgtaa aaaactgaat
    54601 caagcgactc gatatctgac attagtattg gcatttatcc aatctgtcgg tatcactgct
    54661 ggattcaatc aatacgctca attaggtttc gtgaataatc ctaacgtagc aacttacgta
    54721 acgatcggtt tgattctaac agccggtacg atgtttgtta cttggctagg agaacagatc
    54781 acagaaaaag gtatcggaaa tggcgtatca atgatcattt ttgcaggtat catttctaga
    54841 ttgcctgaaa gtatcagaga aatttatgaa gattacttta taaatattga tccttcagac
    54901 atatggaaat ctgctatttt tgtggccatt ttactagtag cggtcttgtt gatcgtgaca
    54961 ttcgtaacat ttttccaaca agctgaacgc aagatcccga tccaatatac gaaacgcgta
    55021 gctggcgcgc ctacaagcag ctatctgccg ttgaaagtaa atgcagctgg agttattcca
    55081 gttatctttg ctagttcgtt tattgctacg ccaaatgctg ttttacaagc attgagcggt
    55141 agattcggtt ctgaaaactg gtacaaagtg atgatggaga tctttaacta taatacagca
    55201 cctggtgcta cgatttatac gattctgatc gttgccttca ctttcttcta cgcctttgtt
    55261 caagtaaacc ctgagaaatt agcggaaaac ttgcaaaagc aaggaagtta tataccaagc
    55321 gtacgccctg gtaaggggac tgaagagtat gtctcaagat tactgatgcg tttaagtaca
    55381 gttggtgcag tcttccttgg tttagtggca ttgcttccaa tcattgctca aatggtttgg
    55441 gatcttccac aatcaatcgg attaggcggt acaagcttac tgatcgttat cggtgtagct
    55501 ttagaaactg cgaaacagtt agaaggctta atgctgaaac gtaaatatgt tggattcatt
    55561 gagtaagaaa gcgtgttgag gtttcccctc aacacacgtt ctcacacatt tattaggagg
    55621 gaaaacaatg aacctcattt taatggggct gccaggcgca ggtaaaggaa cacaagctga
    55681 aaaaatcatt gatgcttatg gtattccgca catctcaaca ggagatatgt tccgcgcagc
    55741 gatgcaaaac gaaacagctc ttggcctgga agcaaagtct tatatggata aaggtgcatt
    55801 agttcctgat gaagtaacaa atggaatcgt gaaagagcga ctagctgaac cagatacaga
    55861 gaaaggcttc ttattagatg gctttccacg tacgctagat caagcaaaag ctctggacgc
    55921 aatgctaaaa gatttgaata aaaaaattga tgctgtcatc gatatccatg ttggtgaaga
    55981 aatcttggtc gaacgtctag ccggccgatt tatctgcagc aattgtggag caacttacca
    56041 taaaattttc aaccctacaa aagttgaaga cacatgtgat cgttgcggtg ggcatgaatt
    56101 ctatcaaaga gaagatgata aacctgagac ggttaaaaat cgtctggcta tcaacatcaa
    56161 aaatagtgaa ccaatcttgg cttattataa agaacaaggt ttgctaaaca ctattgatgg
    56221 tgctcgtgaa atcgatgctg tatttgcaga tgtacaaaaa atcattgaaa aatagcacga
    56281 ttgcccgtag ccgacttgca ttatgcagtt actcttgtca agttcaataa attatgatag
    56341 aatatgtcag tccgacttct agagaatcct ctagatgatc cattttgaga attttgaggt
    56401 gggaactgca gtttccgcca ttttatcgtg tgaaaatgcg aaacaagtac aaggaggtac
    56461 tgtgcgtggc aaaagaagat atgattgaag tcgaaggtac agtcgtcgaa actttgccga
    56521 atgcaatgtt taaagttgaa ctagaaaacg gacaccaagt tcttgctact gtttcaggta
    56581 aaattcgtat gcattacatc cgtatcttac ctggtgacaa agtaacggtt gaattgtctc
    56641 catacgatct taaccgtggc cgtattactt atcgctttaa ataattgtac tccgtaaaac
    56701 tacaggaggt attatcatga aagtaagacc atcagtaaaa ccaatgtgcg aacattgtaa
    56761 agtaattcgt cgtaaaggac gcgttatggt gatttgccca gcaaatccaa aacataaaca
    56821 acgtcaagga taattggagg tgctataaat atggctcgta ttgcaggagt agatattcct
    56881 cgtgataaac gtgtagtagt ttcacttact tatatctatg gtattggtaa cactactgct
    56941 aaaaagatct tagctgatgc tggtgtatct gaagatgttc gcgttcgtga attaacgaat
    57001 gaacaaacag atgctatccg tgcagaagta gataaattaa aagttgaagg ggatcttcgt
    57061 cgtgaagtga acttgaacat caaacgtttg atggaaatcg gttcttaccg tggaatccgt
    57121 catcgccgtg gattgcctgt tcgtggacaa aacacgaaaa acaatgcacg tactcgtaaa
    57181 ggcccagctc gcgctatcgc tggcaagaaa aaataattct taagtgaagg aggttaaaac
    57241 ttcatggcag caaaaaaagt gaatcgtaaa cgccgtgtga agaagaatat agaagcaggt
    57301 attgcacata tccattctac attcaataac actatcatca tgatcactga tactcacgga
    57361 aatgcattag cgtggtcatc agctggttca ttaggtttca aaggaagcaa aaaatcaact
    57421 ccttttgccg ctcaaatggc agcagaaact gctacaaaag cagcaatgga acacggatta
    57481 aagactgttg aagtaacagt taaaggacct ggttctggac gtgaagcagc aattcgttca
    57541 ttacaagcta caggtttaga agtgactgca attcgtgacg tgactccagt tcctcataat
    57601 ggtgcccgcc ctccaaaacg ccgtcgtgtt taatgagtgc cgctcatttt gagttttatc
    57661 agtaacgtca ttgaacaaga cacttttcgt tttgaaaggg gtaaagataa gaatgattga
    57721 gttcgaaaaa ccaagaatcg caaaaattga tgaagaaaaa gattatggca agttcatcgt
    57781 tgaacctctt gaaagagggt atgggactac tttagggaat tccctacgtc gtattttatt
    57841 atcttctttg ccaggtgctg ccatcactaa tattcaaatc gatggtgtac tgcatgaatt
    57901 ctctaccatc aaaggtgtta gagaagacgt cactcaaatc atcttgaaca ttaaaggctt
    57961 agcgctgaaa atgtatggcc aagaagaaaa aacccttgaa atcgatatta ccggacctgc
    58021 tacagtaact gctggcgata ttatcgttga tagtgatgta gaaattctta acaaagatat
    58081 gtacatctgt agtgtctctg aaggagctac gttccatgct cgcttaacag tgaaacctgg
    58141 acgtggttat gttcaagcag atgaaaataa aaaagaagat atgccaattg gcgttcttcc
    58201 agtcgattca atctacacac ctgttcgtcg tgtgaactat caagttgaga acacacgtgt
    58261 tggacaccgt gaagattttg ataaattgac gatggagatt tggacagatg gttcaattga
    58321 accgttggaa gcaatgagtt tgtctgcgaa aatcatgact gaacatttgg atatttttgt
    58381 gaacttaact gatgaagcaa aaaatgctga aatcatggtc gaaaaagaag aaacacaaaa
    58441 agaaaaaatg ttggaaatga cgatcgaaga gttagacttg tctgttcgct cttacaattg
    58501 tttgaaacgt gcaggaatca atactgtaca agaacttaca aataaatctg agcctgaaat
    58561 gatcaaagtc cgtaacttag gacgtaaatc attagaagaa gttaaagcaa aattgcacga
    58621 cttaggttta ggtttacgta aagaagatta aaacctttta cgaaggaggg aaaccaacgt
    58681 gagttatcgt aaactaggac gcacatctag ccaacgtaaa gcgatgttgc gtgatttaac
    58741 aactgattta ttaatcaacg aacgtattgt gactactgaa gctcgtgcga aagaagttcg
    58801 ctcaactgca gaaaaaatga tcactttagg taaacgcgga gatttgcatg cacgtcgtca
    58861 agctgcggct ttcgtacgta atgaagttgc cagcgtgcgt gaagaaaatg aggacatcgt
    58921 cattgaatca gctttacaaa aactgttcaa cgatattgca cctcgttacg cagaacgtca
    58981 aggcggatac acacgcattt tgaagacaga accaagacgc ggtgatggtg caccaatggt
    59041 tgtcttagaa cttgtctaaa atcacactaa taacatcact ttatagatga ttcttttaga
    59101 gtgttatgat gttggaagat atttttccga gtctagctca gcgctgctcc tcaagcgaat
    59161 atcgcttggg gagtaagcac tcatcataaa gtgttttttt ataccttcaa ttacctgtca
    59221 tgacagatat gtttgaaggc ataaaaaaac attttaagcg agaaataatt gaaaattttg
    59281 tctttttttg atagtgttag taggaacttt aggatgaaga aggagtaatc atggagccaa
    59341 ttattgaatt agaaaagata aattataaat accagccaga tgatcttcgc cccgcattga
    59401 aagatgtctc ctttacaatt gataaaggtg agtggatcgc tattattgga cacaatggtt
    59461 caggaaaatc gacacttgcc aaaacgatca atggattgct tctgccagaa tcagggatcg
    59521 tgaaagtggg aaatcaaata ttggatgaag aaaatatttg gacgatccga cagatggttg
    59581 gaatggtttt tcaaaatcca gacaatcagt ttgttggttc gacagtagaa gatgacgttg
    59641 cttttggtct tgaaaatcaa gggattccca gagaagaaat gctagtgcgt gtgaaagatg
    59701 cacttgagaa agttagaatg gctgagtttg cttcacgcga gcctgctcgt ttatcaggag
    59761 ggcaaaaaca acgtgttgcc attgccggcg tggttgcctt acgacctgat atcattattt
    59821 tagatgaagc aaccagtatg ctagatccag aaggtcgtga agaagtgatc tctacgatca
    59881 agaagatcaa agaagaaagt caattgaccg ttatatctat cactcatgat attgatgaag
    59941 cagctaatgc caatcggata ctagtgatga gacaaggcga acttgtccgt gaaggtacac
    60001 caaaagaaat tttttctgct ggtcctgaac tgatcgactt aggtctagat ctaccatttc
    60061 ctgaaaaact gaagagcgca ctgaaagaac gtggggttga tgtgcccagt gaatatatga
    60121 cagaagaaag gatggtggat tggttatgga catccgtttt gaacaagtag acttcactta
    60181 tcagccgaat acaccatttg aacaaagagc cttatttgac atcaatatga cgatcaaaga
    60241 aaacagttat actgcattag tagggcatac cggaagcggg aaatcaacct tacttcagca
    60301 tttgaatgcg cttgttaagc caacaagcgg tacagtccat attggagaac gagatattca
    60361 gccggatacg gataataaga atttaaagcc catccgaaaa aaagttggca tcgtctttca
    60421 gtttccagaa gcacagctat tcgaagaaac ggtagcaaaa gacattgctt tcggtcctaa
    60481 aaactttggt gtcagcgaag aagaagcact agtcctagca aaagaaacat tagaacaagt
    60541 tgggctggat gaaagctatt tggaacgttc gccatttgaa ctttcaggag ggcaaatgcg
    60601 tagagtagca atcgctggtg tgcttgccat gaggccggaa gtacttgtat tggatgaacc
    60661 aacggcagga cttgatcccc agggtagaaa agaaatgatg gagatgtttt ggcgtcttca
    60721 taaggaacag cagatcacta ttgtattagt tacgcattta atggatgatg tagccaattt
    60781 tgcagattat gtctatgtgt tggaaaaggg acgaatcgtt aatagcgggg agccgcaaga
    60841 ggtctttcaa aacattgaat ggctaaaaga aaaacaacta ggcgtaccta ctgccaccga
    60901 gtttgcagaa gaattaatgg ctaaagggat gaactttgct accttgcctt tgacagctga
    60961 agaattagca gacgctatcg tccattatgc tggaggaaat gcccatgatg aataaattga
    61021 tatttggtcg ttatatgcct ggagattcct tgatccatcg attggatccc cgagctaaat
    61081 tattagccag tttttatttt atcggaatca tttttttagc aaataattgg gaaacgtacc
    61141 ttttgttggc atttttcaca ttactttctg tcttcttgtc aaaagtagat ttgaaatttt
    61201 ttatccgagg cattcgccca ttgatctggc taatcctctt cactgtagct ttgcaggtct
    61261 tgtttacaag tggcggagaa acttattgga gttggggtgt tttccatatc actgaatttg
    61321 gtgtgatgaa cggcctcttt attttctgtc gattcgtgtt gatcattttt atgtcgactc
    61381 tactcacgct tactacaccg cctttggaat tatcggatgc gattgagtac ttgcttcgtc
    61441 cattgaaagc cgtacggttc ccagtccacg aaatttcatt gatgctgtcg attgctcttc
    61501 gttttgtgcc tacattgatg gacgaaacag aaaagatcat gaacgctcag cgcgctcgcg
    61561 gtgttgattt tggtgaagga aacctagttc agaaaatgaa agcagtcatt cctttgctga
    61621 ttcctttatt tgtcagcagc ttcaaccgtg cggaagatct tgcgactgct atggaagcaa
    61681 gaggctacaa aggtggggaa ggaagaacga aatatcgtgt attgcattgg cataatagag
    61741 acacgatggt tatcattgct tttgtattat taactgtgct actgatcttt ttgagaggat
    61801 aaacgttcag tgggccgcta tctattcttt tcttgctgat ctgtttgcaa gaaaggatgc
    61861 gagcagtgta tgacaagaaa tattagggtc tgtggcagac taaggtcaca ggcctctttc
    61921 ttttatctga aaagaaagaa cgaaaaaatt ttataaaaaa atcattattc cagataacct
    61981 tttaggaaca aaggagagaa aaacatggta cgttacaaag caatcattgc atacgacgga
    62041 acaaatttta atggattcca aaaacagcca aatgggcgta ctgttcaaga agaagtagaa
    62101 aaaacattac aaaaaatggc aaatggaaaa gaaatcacgg tctttggttc gggaaggaca
    62161 gatgccggag tacatgcgat tgggcaagta atccattttg attatccaga ggagcgtccg
    62221 ttagaacgaa tgcgtttcgc gctagatacc cagtcaccag aggatattgc tgtaagacaa
    62281 gtagaaattg tttcagaaga cttccacgca agatatttgg tcaaagaaaa gacgtatcaa
    62341 tttcgagtgg atatagggaa accacgcagt ccttttcgac gccattatgc aagttatttt
    62401 ccttaccctc ttgatttgga aaaaattcag cgggcgcttc ctgatttatt agggactcac
    62461 gatttcacct ctttttgtgc atcaggaagc tcgatagagg ataaagtacg tacgatctac
    62521 gaggctaaga tggaggtaaa tgaaacaaaa gacgaattgt tgtttacatt taggggaaat
    62581 ggcttcttgt ataagatgat acggatctta gtaggaacgc ttttgaaaat tggcaatggc
    62641 cgattgcctg aagatagtat cccagatatt attgcgaaaa aagatcgtaa tgcagcagga
    62701 cctacagcac atcctgaagg actttatttg tatgaagtga aatatgaata agaggttgtg
    62761 acagaagtgg tcagcttcaa gaaataagaa ggaatttacg aaaattactt ctcaaaattt
    62821 tgcaaaattt cggcttattt tcgaaggagc tacttctgga acaccgtgaa tcagaggttg
    62881 tgaaaaagct gccctgcatc aagtaataag aacaaccaaa caaaaatagc tcgtcatatt
    62941 tttcgtttgg ttgggcttat taccgcagat gcaagctttt gaacaccgtt taaggaagag
    63001 gttgtgaaat cagcgttttg acctgagtat tagagaaaca aacggaaaaa tagttcctca
    63061 tattttgccg tttgttgagc taataccgaa ggtcagctga ttgaacaccg tttaagaaag
    63121 aggtcgtgag cctgtcattt aactctgagt cacaagtaac aatttcaaaa aacagcttct
    63181 catctttgat gaatatcgtg acttgtggac gaggcgttga taagtgaatc atctttttgt
    63241 tacctatttt ttctgtaacc aaaaaacgat ggaacgttgt tttgattgcc cttaatgagg
    63301 acagtcggaa caggtttgtc atttttatat ttaaatggca caaatttttc taattatttg
    63361 tcatttagcg ctgaaaattt ttgctattta tctaaaaaag tgataactac ttaagatgaa
    63421 gcagaatatt tacgccatac ggcatacaac cgcgaaaaat ataaaaaaaa gaaaacgatt
    63481 gaacgcgttt ttgcagtcgc aaaggaaaag catggaatgc gctacatcaa gtatcgagac
    63541 ttggaaaaca atcaggtgta tacgctgatt gtttttgctg caatgaatct gaaaaagttg
    63601 tccacttggc agttggaaca tatgtcttca tatcttttat tatacaaaaa tagcaaaagc
    63661 accagtctac actcttagta aagaggaaac tgatcctttt gtctacattc ttaaagtact
    63721 taaactaagt actttatttt actctttagg attgatacag tagcatctat ccctttatta
    63781 ataatctttt atttttttaa ataaagatgt tgtctccatc ttcaggcact aaaacttttt
    63841 cggaaattcc tttttcttta ttgaaagact ttaattcttc tcttgacagt ccccaatggt
    63901 ttacagcttc catatgaacg gcaataattg tggaatctgg tattgcttta tgcaattcat
    63961 ataaatcgtc tttccccata ataagagatt ctccaactaa aaaatgatta tctccagcat
    64021 ttgctactat gatttctgga ttatactgat caatagtttg tttaacagct tcataccaaa
    64081 ctgtatctcc tgtaaagtat agtgtcttct cagtcgaatg tttgaaaaca ataccgcaaa
    64141 cattacctac ataattcaag atttctcctc tgccatgttt gccttttgtt ttaaccaatt
    64201 gtatagattc aaaaactgtg tcttctcgta gtacctccac atttttaaaa ccatatagtc
    64261 gaatttcatt cgcatcattt tcatcttgca caaataattt tatttcttta ggtaggacct
    64321 ctttcgctat atcgtcccaa tgatctagat gtaaatgtgt tacaataaca gcatcaatac
    64381 cgttgataat atcttcgact ggcattggca aatcaactag aggattcatt tgatcttttc
    64441 ttggtgatgg aaaaggacct ttcgaaataa atggtggaag tgttcctttt tccgctaaca
    64501 ttggatcaat taaaaatttt ttacctccat agtctaagat agctgttgca ttacgaatgt
    64561 gatgtatatt cataaacgtt gtctcctttt tgttgatatg aaatattttt agtataattc
    64621 aattccatac aataaataaa ccgaacaaaa aaagtctttt actattttta cttaatttat
    64681 gaaaggttgt ttaccatgtt agaccaaaca gatataaata tcattgagga actatcaaaa
    64741 aatagtcgaa tcacaatgaa agaacttgga gaaaaagtac atttgactgg acccgctgtc
    64801 tcggcgagag tgacaaaact agaggaaagt ggagttattg aaaattatac agtaaaatta
    64861 aatatggaaa agctagggtt ttcgattcac gcttttttaa ttataattac gcaaaattta
    64921 aatcataaac cctatttatc atttattaaa aatcatgaaa aattcttgat tagaaattat
    64981 aagattagtg gagggggctg ttatcttttg gaatgtagat ttacttcaaa aaaatcaatg
    65041 aacagctttt tggaacagct taatgaatat gcgaattata aattatctat tgttatagat
    65101 taataataaa actagcagat ggtaaaaata ctaatatgcg agacacacat tcaaccataa
    65161 ctatataact tatcaattta aaactaaact gatggaaaca agtaaggcaa aaacatttat
    65221 attttgccct acttattttt ttaattaaat tcattgatga ttcatattta gaaaattcta
    65281 tgaaggccaa atgagtatcc tgtcactttt ttagataaat agcaaaaatt ttcagcgtta
    65341 aatgacaaat aattagaaat atttgtgcca tttaaatata aaaatgacac caagtatatc
    65401 atgaacgcac aaaaagacca acagggtata ccctgttggt ctaaataa
//
LOCUS       DAFENC010000012        59443 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.012, whole genome shotgun sequence.
ACCESSION   DAFENC010000012
VERSION     DAFENC010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59443
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.012"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            212..604
                     /locus_tag="LP493_001020"
     CDS             212..604
                     /locus_tag="LP493_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBL2133183.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="LP493_001021"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="LP493_001021"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HBL2133184.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3155..4765
                     /locus_tag="LP493_001022"
     CDS             3155..4765
                     /locus_tag="LP493_001022"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HBL2133185.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5057..5926
                     /locus_tag="LP493_001023"
     CDS             5057..5926
                     /locus_tag="LP493_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HBL2133186.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6091..7362
                     /locus_tag="LP493_001024"
     CDS             6091..7362
                     /locus_tag="LP493_001024"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBL2133187.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7359..8654
                     /gene="rho"
                     /locus_tag="LP493_001025"
     CDS             7359..8654
                     /gene="rho"
                     /locus_tag="LP493_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HBL2133188.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8753..9016
                     /locus_tag="LP493_001026"
     CDS             8753..9016
                     /locus_tag="LP493_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HBL2133189.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9461..9910
                     /locus_tag="LP493_001027"
     CDS             9461..9910
                     /locus_tag="LP493_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL2133190.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9967..11385
                     /locus_tag="LP493_001028"
     CDS             9967..11385
                     /locus_tag="LP493_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL2133191.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11385..12245
                     /locus_tag="LP493_001029"
     CDS             11385..12245
                     /locus_tag="LP493_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBL2133192.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12419..13192
                     /locus_tag="LP493_001030"
     CDS             12419..13192
                     /locus_tag="LP493_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL2133193.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13339..13704
                     /locus_tag="LP493_001031"
     CDS             13339..13704
                     /locus_tag="LP493_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HBL2133194.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13852..15060)
                     /locus_tag="LP493_001032"
     CDS             complement(13852..15060)
                     /locus_tag="LP493_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2133195.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15079..15357)
                     /locus_tag="LP493_001033"
     CDS             complement(15079..15357)
                     /locus_tag="LP493_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133196.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15511..16206
                     /locus_tag="LP493_001034"
     CDS             15511..16206
                     /locus_tag="LP493_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBL2133197.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(16648..17445)
                     /locus_tag="LP493_001035"
     CDS             complement(16648..17445)
                     /locus_tag="LP493_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HBL2133198.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17442..18626)
                     /locus_tag="LP493_001036"
     CDS             complement(17442..18626)
                     /locus_tag="LP493_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBL2133199.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18651..19898)
                     /locus_tag="LP493_001037"
     CDS             complement(18651..19898)
                     /locus_tag="LP493_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBL2133200.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20113..21858
                     /gene="dnaX"
                     /locus_tag="LP493_001038"
     CDS             20113..21858
                     /gene="dnaX"
                     /locus_tag="LP493_001038"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HBL2133201.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21878..22192
                     /locus_tag="LP493_001039"
     CDS             21878..22192
                     /locus_tag="LP493_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HBL2133202.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22217..22813
                     /gene="recR"
                     /locus_tag="LP493_001040"
     CDS             22217..22813
                     /gene="recR"
                     /locus_tag="LP493_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HBL2133203.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22877..23521
                     /locus_tag="LP493_001041"
     CDS             22877..23521
                     /locus_tag="LP493_001041"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HBL2133204.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23536..23865
                     /locus_tag="LP493_001042"
     CDS             23536..23865
                     /locus_tag="LP493_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HBL2133205.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23879..24817
                     /gene="holB"
                     /locus_tag="LP493_001043"
     CDS             23879..24817
                     /gene="holB"
                     /locus_tag="LP493_001043"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HBL2133206.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24853..25677
                     /locus_tag="LP493_001044"
     CDS             24853..25677
                     /locus_tag="LP493_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HBL2133207.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25670..26017
                     /locus_tag="LP493_001045"
     CDS             25670..26017
                     /locus_tag="LP493_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HBL2133208.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26086..26958
                     /gene="rsmI"
                     /locus_tag="LP493_001046"
     CDS             26086..26958
                     /gene="rsmI"
                     /locus_tag="LP493_001046"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HBL2133209.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27067..28188
                     /gene="dinB"
                     /locus_tag="LP493_001047"
     CDS             27067..28188
                     /gene="dinB"
                     /locus_tag="LP493_001047"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HBL2133210.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28242..28844)
                     /gene="nrdG"
                     /locus_tag="LP493_001048"
     CDS             complement(28242..28844)
                     /gene="nrdG"
                     /locus_tag="LP493_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HBL2133211.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29159..31348)
                     /gene="nrdD"
                     /locus_tag="LP493_001049"
     CDS             complement(29159..31348)
                     /gene="nrdD"
                     /locus_tag="LP493_001049"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HBL2133212.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31647..32441
                     /locus_tag="LP493_001050"
     CDS             31647..32441
                     /locus_tag="LP493_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2133213.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32431..34473
                     /locus_tag="LP493_001051"
     CDS             32431..34473
                     /locus_tag="LP493_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2133214.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34754..34903
                     /locus_tag="LP493_001052"
     CDS             34754..34903
                     /locus_tag="LP493_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HBL2133215.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34914..36428
                     /gene="dltA"
                     /locus_tag="LP493_001053"
     CDS             34914..36428
                     /gene="dltA"
                     /locus_tag="LP493_001053"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HBL2133216.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36425..37630
                     /gene="dltB"
                     /locus_tag="LP493_001054"
     CDS             36425..37630
                     /gene="dltB"
                     /locus_tag="LP493_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HBL2133217.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37675..37908
                     /gene="dltC"
                     /locus_tag="LP493_001055"
     CDS             37675..37908
                     /gene="dltC"
                     /locus_tag="LP493_001055"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HBL2133218.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWCTPNKIIQQATALKG"
     gene            37911..39179
                     /gene="dltD"
                     /locus_tag="LP493_001056"
     CDS             37911..39179
                     /gene="dltD"
                     /locus_tag="LP493_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HBL2133219.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39320..40402
                     /locus_tag="LP493_001057"
     CDS             39320..40402
                     /locus_tag="LP493_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HBL2133220.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40402..41205
                     /locus_tag="LP493_001058"
     CDS             40402..41205
                     /locus_tag="LP493_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBL2133221.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41275..42015
                     /locus_tag="LP493_001059"
     CDS             41275..42015
                     /locus_tag="LP493_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBL2133222.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42026..43030
                     /locus_tag="LP493_001060"
     CDS             42026..43030
                     /locus_tag="LP493_001060"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBL2133223.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43075..44919)
                     /locus_tag="LP493_001061"
     CDS             complement(43075..44919)
                     /locus_tag="LP493_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133224.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
     gene            45131..45649
                     /locus_tag="LP493_001062"
     CDS             45131..45649
                     /locus_tag="LP493_001062"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBL2133225.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            45777..46460
                     /locus_tag="LP493_001063"
     CDS             45777..46460
                     /locus_tag="LP493_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HBL2133226.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            46769..46842
                     /locus_tag="LP493_001064"
     tRNA            46769..46842
                     /locus_tag="LP493_001064"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:46803..46805,aa:Arg,seq:tct)
     gene            47001..47360
                     /locus_tag="LP493_001065"
     CDS             47001..47360
                     /locus_tag="LP493_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HBL2133227.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            47483..49114
                     /locus_tag="LP493_001066"
     CDS             47483..49114
                     /locus_tag="LP493_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HBL2133228.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(49176..49817)
                     /locus_tag="LP493_001067"
     CDS             complement(49176..49817)
                     /locus_tag="LP493_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBL2133229.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    50003..50079
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            50099..50407
                     /gene="rplU"
                     /locus_tag="LP493_001068"
     CDS             50099..50407
                     /gene="rplU"
                     /locus_tag="LP493_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HBL2133230.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            50434..50778
                     /locus_tag="LP493_001069"
     CDS             50434..50778
                     /locus_tag="LP493_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HBL2133231.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            50791..51084
                     /gene="rpmA"
                     /locus_tag="LP493_001070"
     CDS             50791..51084
                     /gene="rpmA"
                     /locus_tag="LP493_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HBL2133232.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            complement(51177..52325)
                     /locus_tag="LP493_001071"
     CDS             complement(51177..52325)
                     /locus_tag="LP493_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL2133233.1"
                     /translation="MAMIKQYKKKNGEKAWYFKTYLGIDPLTGKKKYTTKRGFRTQKE
                     AKTALSRLELELQKTGMPTSTNTTFKEAAELWLESYKKTVKESSYSRTKIIFNKHIYP
                     KFGNIKLSKINTAYCQKVVNDWSEKGTSKQYPLFINYMNKVFKYAINIGLTSDNPTLN
                     LLIPKPQIKTEKKLKLYTKEQLELFLNEVSQEQNPYFKNRDYTLFRLLAFSGCRIGEI
                     LALTWDNINFKTNEMAIKKTVARSDKYYISETPKTKKSNRIIYLDEKTIKQLKFWKLE
                     QRKYLFQLGFTKANYLFTNDENNFTINQSVAERYNIYRERAGLPYIGLHGFRHTHASM
                     LYEAGADHKEVQERMGHANIKTTMDTYTHITNSKKEETTQKLTNYINF"
     gene            complement(52337..52648)
                     /locus_tag="LP493_001072"
     CDS             complement(52337..52648)
                     /locus_tag="LP493_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133234.1"
                     /translation="MIYTEFKEWLEKSTTGYETFIIKATNYQIEKNKNRPQKKRWDDK
                     KIDKAVLEMWKQVVTNLYQTIRKEKGVPLINGKEIWLEFIEEQGLIEFFNDSMAELEF
                     E"
     gene            complement(52701..53096)
                     /locus_tag="LP493_001073"
     CDS             complement(52701..53096)
                     /locus_tag="LP493_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBL2133235.1"
                     /translation="MIINELGVKVEERENLDADGHYVACMNTIVIKANLSKYRRQRTL
                     LHELGHASKHHDNYFLYNLAFSLHSKMEYEADRFMIEKLLDRYIAKSELEPHNINYMK
                     FIEDNNLSVRFEPLVKELLKARIYCYAAL"
     gene            complement(53132..53476)
                     /locus_tag="LP493_001074"
     CDS             complement(53132..53476)
                     /locus_tag="LP493_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2133236.1"
                     /translation="MLFERVKELCKKRGISISELENRIGFGKNSIYKWKTQSPKIETL
                     QKVADYFHVSTDYLLGRTDDPNAGVAPEERKLTVEEALASVMSSDGKPLTDNDREILS
                     AMIEAYLEKKDN"
     gene            53777..53998
                     /locus_tag="LP493_001075"
     CDS             53777..53998
                     /locus_tag="LP493_001075"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133237.1"
                     /translation="MKQNKKTPSAKGALITLNFKDQKFSAVVDEIHPQEHQKNSFATD
                     EKKTQKRSEKVLRIIQFLLEKIRHFGSLF"
     gene            54125..54901
                     /locus_tag="LP493_001076"
     CDS             54125..54901
                     /locus_tag="LP493_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HBL2133238.1"
                     /translation="MNTPQIFNFEQHEVRTVTIHDEPFFVGKDVAKVLGYQNGSRDIN
                     RHVDVEDRQNYQNGTFESPRGLTIINESGLYSLILGSKQPNAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATKLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMRQGYTKSHTTEIPK
                     SDGGTKVVMNTKWTQKGRLFIYESLKKEGYIPEIDLLEEE"
     gene            54904..55092
                     /locus_tag="LP493_001077"
     CDS             54904..55092
                     /locus_tag="LP493_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2133239.1"
                     /translation="MSQEFILKVRIQLAKYGKSQNWLADTIGISRPYMSDIMNGRRKP
                     DKQIKPIEAALAELEKEK"
     gene            55094..55378
                     /locus_tag="LP493_001078"
     CDS             55094..55378
                     /locus_tag="LP493_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133240.1"
                     /translation="MQITIPDNLVVSELTTQITNAVLNSLDERLHLMNKSVELPPYPN
                     KSEVKKVLGIGDDKLTHWISLGLKTQQWSKLDIRIERSELQRFLKENFEF"
     gene            55399..55587
                     /locus_tag="LP493_001079"
     CDS             55399..55587
                     /locus_tag="LP493_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133241.1"
                     /translation="MSYTLQQEHQILGLIKQRRKQLQDDRAALRKSDELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            55913..56152
                     /locus_tag="LP493_001080"
     CDS             55913..56152
                     /locus_tag="LP493_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133242.1"
                     /translation="MENELSTLDQYLADPDWGKSNLQLVANKYEKSIDEAIVALTDAA
                     SITADDSKWTKRDLGILKRGVNWLEDQYREETKEK"
     gene            56158..56844
                     /locus_tag="LP493_001081"
     CDS             56158..56844
                     /locus_tag="LP493_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133243.1"
                     /translation="MFKPLIDSYSAVLKKFKGNDIGATINEEVNIERLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGREISLK
                     DESNTTVSDANILANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            56847..57677
                     /locus_tag="LP493_001082"
     CDS             56847..57677
                     /locus_tag="LP493_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HBL2133244.1"
                     /translation="MAEISWIKLKTTMFDDEKIRLIQAVPESDAIIVIWIRLLVLAGK
                     TNDDGLIYIQRNMPYTEEMLATLFGKNVNTVRLALTTLANFNMIDLSSDGLIAISNWE
                     KHQNIEGMDKVRLKNAERNRKYRERKRQERLKLENDVSVTSRDGTDKDIEEDKDIDKE
                     EKKGKYSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADTIRLMEERDKASIEAIEYV
                     INWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKKNHKKQSQKLQYSNPSEYDDLPI
                     "
     gene            57694..58545
                     /locus_tag="LP493_001083"
     CDS             57694..58545
                     /locus_tag="LP493_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL2133245.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALEKAKSYTNEVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNTELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            58542..58901
                     /locus_tag="LP493_001084"
     CDS             58542..58901
                     /locus_tag="LP493_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HBL2133246.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQA
                     PLILAKKYRNTFKEERF"
     gene            58916..59077
                     /locus_tag="LP493_001085"
     CDS             58916..59077
                     /locus_tag="LP493_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBL2133247.1"
                     /translation="MTTEEVIQMRIRNIQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            59074..59379
                     /locus_tag="LP493_001086"
     CDS             59074..59379
                     /locus_tag="LP493_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133248.1"
                     /translation="MSVDKKATMKRIAELTKSESWQEDKEIVAEVQKLGKSMWTEKPK
                     RKTPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEER"
BASE COUNT        19334 a        10180 c        12217 g        17712 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacgag aaactaacgg aaaaatagtt
     2041 cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa caccgtttag
     2101 tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa gcaaaaacag
     2161 cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt tgaacaccgt
     2221 ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat tttgtgaaaa
     2281 tggctttcta catttttgca taaatttggc ttaataccga gaaactggct tttgaatacc
     2341 gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat aatttcaaaa
     2401 acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc aggagaacac
     2461 cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt ttacttatgt
     2521 gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag gtcatctttg
     2581 aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat atgccaaaaa
     2641 tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg aaagaaaaag
     2701 attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt agttctttgt
     2761 taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta tttcacttaa
     2821 aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg tttatatcaa
     2881 gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa taatttctca
     2941 aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta cttgactttc
     3001 ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga agtttacaga
     3061 aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc tgagactttt
     3121 cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt ttgtgaccgg
     3181 cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac gcttattgaa
     3241 aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg tggatccggg
     3301 gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg ctgaaacaga
     3361 tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat actccaacgt
     3421 gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg aatacttggg
     3481 agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa tcatgcgagc
     3541 agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag taggggatat
     3601 agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg gtacagataa
     3661 tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag aaatgaaaac
     3721 taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac cgaatatttt
     3781 ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg cacaattttg
     3841 tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt actccatccc
     3901 attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa aactagatac
     3961 accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga acttgaagaa
     4021 aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat atatctcagt
     4081 agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga tcgattggat
     4141 caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg cagatggaat
     4201 cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag cgattcgtta
     4261 tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga tggcttgtgt
     4321 cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa cgaatccaga
     4381 tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga atttgggtgg
     4441 aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga cggctgaagc
     4501 atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt tcaataacaa
     4561 atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac cagataaccg
     4621 tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc aattccaccc
     4681 agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg tcggagcatc
     4741 attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa agtagcaaga
     4801 gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta ttatttgtag
     4861 gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat attttatttt
     4921 ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa ctaccgaaat
     4981 gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt ttacaaaact
     5041 taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag ctgctcgtaa
     5101 aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc aagcaatcct
     5161 tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg gtgcagctaa
     5221 atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg aagcaatgaa
     5281 catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg ctttggaatg
     5341 tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat ttgaagaaaa
     5401 cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct cagttgaatg
     5461 tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg aattagctga
     5521 tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt gcggtatcgg
     5581 taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc acttacaagc
     5641 aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat caggtattcc
     5701 tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg ttaacactga
     5761 attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta aagataaaga
     5821 aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa tcgttgaaga
     5881 tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat ccacataaca
     5941 gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct tttttactta
     6001 aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag catatccatg
     6061 aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa aggaaaccga
     6121 cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc attgattcca
     6181 gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat acaagatgtt
     6241 cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc caacaacata
     6301 ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa aatcaatagt
     6361 ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga agcggtagta
     6421 ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt caaaggattt
     6481 gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg gacagaaaat
     6541 aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc aacgatcaat
     6601 gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc tgcacgagaa
     6661 ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt tcgaggagcg
     6721 ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg gcatttcatg
     6781 attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt aggaaatggt
     6841 atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa attgcaggaa
     6901 attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc gaaagaatta
     6961 aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct gcagcagcca
     7021 cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac gatctatgcg
     7081 aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac cgtggaagga
     7141 aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt ggcttctgat
     7201 cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac aacgacgatt
     7261 tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact aacagcctta
     7321 ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat ttgacaatgg
     7381 cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa tttaaaattc
     7441 cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt gcacaagcag
     7501 agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa gatggttacg
     7561 gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt tctgcctcac
     7621 aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc cgtccaccta
     7681 aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga aaagatccgg
     7741 aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg caaagacagc
     7801 ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc ttttctccaa
     7861 tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa acttctgtat
     7921 taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta atcgttctac
     7981 tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa ggcgacgtgg
     8041 tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa ttagtattgg
     8101 aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg gatagtatta
     8161 ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca ttgagtggcg
     8221 ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca agaaacatcg
     8281 aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga agccgtatgg
     8341 atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa ctttcacgtg
     8401 aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt acccgaaaag
     8461 aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga aaaaatatga
     8521 ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa acaaaaaaca
     8581 atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat ccgaccagaa
     8641 atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg ttgtaaatcg
     8701 acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa tcatgaaaga
     8761 aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg gtttcaaatt
     8821 cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg gtaatacata
     8881 cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg gacgtcaaaa
     8941 attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc tcaaagacgc
     9001 aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta tctgataggg
     9061 atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct gaaaaagtcg
     9121 taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta tccacttgat
     9181 aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa accatttacc
     9241 taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta tagacttgcg
     9301 attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga tgggtctttt
     9361 tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg acctcagttc
     9421 caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg atcaattgat
     9481 cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat tatttgagcg
     9541 aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag tcgttaaggc
     9601 actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg ggattcccca
     9661 tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag ccaaattaac
     9721 ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg tagttcctga
     9781 aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat tgatgaatgc
     9841 agattttaga aagggaataa aagaagccac tacgccagca gatatcatca gacagattag
     9901 tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa aaggaggaaa
     9961 ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca tacttatatg
    10021 tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa attcgaaaca
    10081 caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc agatgcaatc
    10141 attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa agtaaagcgt
    10201 gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc attgagagat
    10261 attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa aaagccgaca
    10321 atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat cgcaggcgga
    10381 atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa ctcagcagac
    10441 tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt tgccatgatg
    10501 gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg ttttgcccca
    10561 ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg cggaatgatt
    10621 ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag cgtaaaaaaa
    10681 gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt aattattggg
    10741 cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc tttgacaaat
    10801 tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat cgggatcatg
    10861 atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc gatcggtttg
    10921 atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat gacacctccc
    10981 ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga agaacggact
    11041 tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc tataccgttt
    11101 gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc agtcgctgca
    11161 gggatttcca tggcagtagg agttacttca atggcacctc atggagggat ttgggtgatg
    11221 ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc atcaggtaca
    11281 gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa aaaacaagac
    11341 aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta tatacaatga
    11401 aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc aatatttgca
    11461 gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca ccagtaatct
    11521 tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg gcagtaagag
    11581 cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc ggtacgatag
    11641 aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat gcgtctttga
    11701 aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct catgcggtaa
    11761 atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct gaaggaggtg
    11821 ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa gaaacaggaa
    11881 tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa aacagaactc
    11941 caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt ccatttgttt
    12001 tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa tacggagttg
    12061 ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg agagaaatat
    12121 tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct aataaaaagg
    12181 tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag gctagtttat
    12241 actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat accctcttaa
    12301 ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc tcgaagccaa
    12361 tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg gtgattttat
    12421 gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa acaaccaatt
    12481 tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga ttaaacgtga
    12541 ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg ccatgcttat
    12601 tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag aagaagaaac
    12661 agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata tggtcttatt
    12721 cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat ttgatggttt
    12781 gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata caacggcaaa
    12841 agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg gttcaaaagc
    12901 ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc gcgggctaga
    12961 tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa aagcttttag
    13021 aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac ataaattcat
    13081 gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag aactgacaaa
    13141 agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat aaattattac
    13201 gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc tcgcttctct
    13261 cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt ttttatccag
    13321 gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc aatcatgatc
    13381 tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat ggattcaacg
    13441 attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt gatcttacgt
    13501 aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt tatcttgtgg
    13561 ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt gattcctgct
    13621 ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca aggcatcgta
    13681 ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga taaatgaaag
    13741 ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta ctcaaaaaac
    13801 cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag atcaaatttc
    13861 atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc ggccattaac
    13921 aagatagagt gctgtacata tcaatggaat gactccggca atcacataca atcctctaaa
    13981 tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc ctaggtctaa
    14041 accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga tttttaaaca
    14101 aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg ctccagagat
    14161 aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg ttaagaataa
    14221 atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc cagtcaatgg
    14281 acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag cagcaactaa
    14341 gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag aaagacccat
    14401 caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat tgatattcca
    14461 tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag gaaagacaag
    14521 gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga aacgaaaatc
    14581 agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta aactagtact
    14641 taatccataa taattgatgc cttccccttt tttagatgca gggatatatg cagtaacgat
    14701 agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc gaactaaata
    14761 caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat agaagatcgc
    14821 gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca tgaataagcg
    14881 tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc tcaagctggc
    14941 gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat aaatcaggta
    15001 gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt tcttttccat
    15061 gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt gaacttctac
    15121 atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat ctcttgtaga
    15181 cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca ctgctttgat
    15241 caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt tcatatcaaa
    15301 tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt aattcatgtt
    15361 ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa aaaaggaaaa
    15421 aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta gtaaaatacc
    15481 tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag tttggatggg
    15541 ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga ttttccgatt
    15601 atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc ccatacgtat
    15661 atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag agaatttaac
    15721 cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata ttcacaattc
    15781 atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta tcgaatcaat
    15841 cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta tgtaaaagag
    15901 tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct attaaacgga
    15961 aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg tgtgcggaca
    16021 gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa attttgtggc
    16081 atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga tggtattatc
    16141 accgttaaag accatcatat cgttattttg aatatggact tgttagaaga caatattatc
    16201 ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag agaaacaaac
    16261 ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt cagctgattg
    16321 aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca aggaacaatt
    16381 tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg agttggtagg
    16441 agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa taagaagagc
    16501 caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt agatgtaagc
    16561 ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt cacagccctt
    16621 tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc caaaagtccc
    16681 gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg ggcttttggg
    16741 gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag ttaatttgat
    16801 actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat aacgcgaaac
    16861 agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa tgatgatttc
    16921 tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta cacgataatg
    16981 tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag cttttgcagc
    17041 attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg aatcgattct
    17101 gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt cacgctgtcc
    17161 catatctaat agcaatactg agccattttg atcatttccg actgcgtctc ttaagtaatt
    17221 atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca agactcgtcc
    17281 tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt gatctgttgt
    17341 gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca ccggccagcc
    17401 aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa gtaacctccg
    17461 atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc caattttttc
    17521 tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc gtagtagtag
    17581 acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag taatacgtaa
    17641 ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt tgtatatcca
    17701 tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg aatctgtgat
    17761 ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa atactggctt
    17821 ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat cttttgttgc
    17881 gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc tgctcttgaa
    17941 acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat gcggataact
    18001 gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata agggaaatac
    18061 acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac aaaccatttt
    18121 ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc aaaaggaagt
    18181 actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg attatggcag
    18241 tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc acagttggga
    18301 caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt atctgaaaaa
    18361 ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag ctgttcttgg
    18421 gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc gccagccata
    18481 cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata gatattcagg
    18541 cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc gccgcaatta
    18601 ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa ttaattaacg
    18661 gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc gttggaaaga
    18721 tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac gttttctaca
    18781 ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc gcaaactgga
    18841 catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc tgcttgttgt
    18901 ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt tgcattcatt
    18961 cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc ggctgcttcc
    19021 ataccacgtg caatggaacc ttgcacgtat ccttcacgta cgctaggatc acctagcatc
    19081 gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga aatgctggct
    19141 acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc caatgcagta
    19201 tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg ttgaccatct
    19261 gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa atactgctca
    19321 ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt ataaaataaa
    19381 atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa ttctgcgtta
    19441 tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc ctttatttct
    19501 tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa tttgaatcgg
    19561 tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg agctgcgtca
    19621 tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc accatcgacc
    19681 aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa aacatcttct
    19741 gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc ttttgtcatg
    19801 accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc tgccagaccg
    19861 ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc ctctgattca
    19921 gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga aacttctcgg
    19981 actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa aaagccgaga
    20041 aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat tttttaaaaa
    20101 agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca gcgtttcgaa
    20161 gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt ttcccacaaa
    20221 acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag tgcagcaaag
    20281 attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg caacgaatgc
    20341 gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat cgatgctgcc
    20401 agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta tgcgcctaca
    20461 aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac aggagctttc
    20521 aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat cttagcaacg
    20581 accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt tgattttaaa
    20641 cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga atcgactatc
    20701 agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg gatgcgggat
    20761 gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac tttagatgat
    20821 gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt gagtgcttgc
    20881 gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc agccggcaaa
    20941 gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct gatgtatcag
    21001 caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt tacagaattg
    21061 gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag cgatactcaa
    21121 aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac agtcaaactt
    21181 gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga tgatcagata
    21241 gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga actacgcagt
    21301 aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca taaaaaacag
    21361 acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga agcgacaaga
    21421 cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct atctgtcact
    21481 cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg actagtgatt
    21541 gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt gcagctttcg
    21601 gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt ttatattaca
    21661 agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga agagggaaca
    21721 gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc tcaagaacaa
    21781 gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc cgaagctgtt
    21841 acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa tgggcaatat
    21901 gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag cacaagagct
    21961 gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag cggtttttac
    22021 aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc ctgatgatat
    22081 cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac aaattgatgt
    22141 ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt agttttaaac
    22201 tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg acagctacat
    22261 gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata cgatcgatat
    22321 gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac gcgatttgca
    22381 tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat gtagaaatcc
    22441 ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa tggcaatgga
    22501 aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat caccgatgga
    22561 agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc atgatgcaga
    22621 tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa cagctatgta
    22681 tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac atggtctgtc
    22741 tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg tcgaaggaag
    22801 acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa gcagcacaag
    22861 agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg atggtgcagg
    22921 aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa aaacagaaat
    22981 cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag cagtgatcct
    23041 tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg cagcagcaag
    23101 aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa tcgttttatg
    23161 cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca tcggcgttac
    23221 cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt ttacccttta
    23281 tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac aaaatcaaat
    23341 cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg cttacttaaa
    23401 gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa gctttgaaga
    23461 agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt ttgaaaacta
    23521 ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga cagcaaccgt
    23581 ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc gacaggcggc
    23641 ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg tgtagaagaa
    23701 gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc tacacctgtt
    23761 acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga agtaggcggt
    23821 gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga gctgagctat
    23881 gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc ttcaacggag
    23941 ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag gaacaggaaa
    24001 acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga aagacaatct
    24061 gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc cagatgtttt
    24121 ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt tgcagacgga
    24181 attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag aagctgaaaa
    24241 aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc ctggagattt
    24301 tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc aatctcgttg
    24361 tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat tgcaagaaga
    24421 gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt taggaaaagc
    24481 agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt atcaatggtt
    24541 cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa aattggtaaa
    24601 atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt tttattatca
    24661 ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac agataaacca
    24721 gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca gttttcaggc
    24781 tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg atgatgatca
    24841 aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg tcatatctat
    24901 tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt cgaatctcag
    24961 caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc caatgacctt
    25021 cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga aaaagacaaa
    25081 aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt gcagttgcgt
    25141 gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa attgattttt
    25201 tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct ggccgctgta
    25261 tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa gataataggc
    25321 ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga tttcgtgcct
    25381 gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa aatttccggt
    25441 ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga gacagcgaaa
    25501 aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg gaaagtcgta
    25561 gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga aaatcctgtc
    25621 gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa tggataagag
    25681 atcattatac gacggattga atcaattaga atcagagttg agaaatacat taacagaact
    25741 tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt tggagatgga
    25801 aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag ctccagctga
    25861 aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt atgaagaagg
    25921 attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc cttgtgcgtt
    25981 ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag gagactggag
    26041 cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta taatcaaaaa
    26101 agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc aattggaaat
    26161 ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct tatcgcaagt
    26221 gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac accccaaaaa
    26281 agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt gttaaaagaa
    26341 ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga tcctggacat
    26401 gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc aggacctaca
    26461 gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt attttatggc
    26521 ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa agaacagaca
    26581 gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac gaatttctta
    26641 gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt ccatgaagaa
    26701 taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc agtaaagggt
    26761 gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga agttgatgaa
    26821 gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga aaaaccaaat
    26881 gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt ctaccgtcag
    26941 taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa tgaggaaatc
    27001 agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa tgaataagag
    27061 gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa aatcattcat
    27121 attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga gtttcgcgga
    27181 catccattag taattgccag acaccccagt gacactggtg ggcgtggagt agtgactaca
    27241 gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca aaaagcgtat
    27301 gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag cgatatttcc
    27361 aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt tagtatcgat
    27421 gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat caaaatcgcc
    27481 cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc gggagtaagt
    27541 tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg aatcacggta
    27601 gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa atttcatggg
    27661 gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg aaaagaccta
    27721 tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta ttctctttat
    27781 cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg aaaatctgtg
    27841 ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct gactcagttg
    27901 cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca tgggaaaaca
    27961 gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt gacattgcca
    28021 gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg ggaggaaatc
    28081 ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct ggacccgatg
    28141 acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa acagctttga
    28201 gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa gtcttgcttt
    28261 ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac aacttgattg
    28321 gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg aaattgtagt
    28381 tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat ttgcgaaagg
    28441 agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc tgtccatgac
    28501 cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg cagacaaaca
    28561 tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta atcgttgcgc
    28621 aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata tcggaaattt
    28681 tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac gtaaagactg
    28741 ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat atagttttgg
    28801 ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa acttctttca
    28861 tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat aaataagaac
    28921 aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga gggcgttcaa
    28981 agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct cttattctga
    29041 ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg aaaaatatga
    29101 ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt tcacaacctc
    29161 atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc atcggacgag
    29221 cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt tttggatcat
    29281 gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca ccttcgaaac
    29341 cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt ttgtcatatg
    29401 caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg tattcacagt
    29461 agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc aatttttcaa
    29521 atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat tctttatctg
    29581 tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg tcagttagac
    29641 tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc catgcatctg
    29701 cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct gggtttgttt
    29761 cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag cctaacgata
    29821 cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa agacgtttcc
    29881 cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct ttacaacgtt
    29941 ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt aactgccaga
    30001 atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat gtaacaacac
    30061 ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac ccttgcaaga
    30121 atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt ttatcgtaat
    30181 tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt ttgatgtcgt
    30241 aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc agtttaggga
    30301 agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa attgcttttt
    30361 gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg aaaggagttt
    30421 gtccatttga agtaaataag gtattgattt catattccaa actttgcata gcatcgaaga
    30481 tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa tcgatccatt
    30541 cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca agcaattcat
    30601 ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca ataatctgtg
    30661 agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca ttgccgattt
    30721 tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc atcggtgtat
    30781 aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca tttgctatat
    30841 gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc agatctcgct
    30901 gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt tggtccttgt
    30961 tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca aaatctcgtt
    31021 tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct agtaatatat
    31081 gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg cttttgattt
    31141 cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt gataatgagc
    31201 cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca tcgaaatcaa
    31261 catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc tgagtaacga
    31321 cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt gttcttgtct
    31381 atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag tattcaatgt
    31441 gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa aaaaggtgaa
    31501 aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa aataattgaa
    31561 taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa ttattcgtag
    31621 atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa gaattggaaa
    31681 agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct cccgtcaaag
    31741 ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt atgggcccaa
    31801 gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg cctacgatgg
    31861 gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag ctcagtgact
    31921 ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat accctaaatg
    31981 caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag gaaatggaaa
    32041 agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa cggtatcccg
    32101 atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt gttgttcagc
    32161 cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg gctacagaat
    32221 tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg ttagtcaccc
    32281 atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat ggtgtgattt
    32341 tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta atagacatgc
    32401 aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt taaaagtttt
    32461 tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc cgtaatgatc
    32521 tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc aagtcaagat
    32581 acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt tttgcttttt
    32641 ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat aggcatctat
    32701 cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga aatcatgata
    32761 attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc caaactcttt
    32821 tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt tatctccatt
    32881 ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt atctgtatat
    32941 tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa agaacaagca
    33001 gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat cgggttacta
    33061 cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc atggatgatc
    33121 agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt tttcgtttgt
    33181 gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat catattgagt
    33241 aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac gcaagttcat
    33301 ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat ttctttaatg
    33361 acaattggcg gcacggctag tatctctact attttatcct accaggagaa agtttcctcc
    33421 ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat tctagcagag
    33481 gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg gagtatctat
    33541 agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga aacacaatat
    33601 caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc acctggtcat
    33661 actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata tggatctagt
    33721 attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag tgtattaggt
    33781 gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt ttttgaaaaa
    33841 gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa taatgaaaaa
    33901 atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt ttattattct
    33961 tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact tccggatgac
    34021 caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc ttccagctat
    34081 tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac actatttgtc
    34141 gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt agcagaagca
    34201 gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca aagaaggatc
    34261 agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat attagggatc
    34321 actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc cgattactgg
    34381 ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta tgtcattacg
    34441 agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa gataataaat
    34501 agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga tttttgtcac
    34561 aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa aaagcagtga
    34621 tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa aacggtttct
    34681 gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg aggttatatg
    34741 aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt ggggaaaatt
    34801 catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc tgtatcacta
    34861 taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag agtatggaaa
    34921 tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat cgagttgctt
    34981 atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac gcacttgctt
    35041 attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc aatttggagt
    35101 ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat ttgccgattg
    35161 aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa ccatctatgg
    35221 tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata acaaaaaaag
    35281 aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc gtaaaaggta
    35341 cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa ggcgtacaaa
    35401 tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt gggatcaagc
    35461 ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta ttttctattt
    35521 atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt gttcaagact
    35581 ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt tctactccat
    35641 catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg ccggaattgg
    35701 acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt ctacttgatc
    35761 gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact gtagctattt
    35821 caagtattca gattgaccag catgtactag atagttatga ccgactaccg attggctacg
    35881 taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca aaaggagaaa
    35941 cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac aatcccgaaa
    36001 agacagctgc tgcgttcttt tgtcaaaatg acttagcaag ttaccataca ggggatgcag
    36061 gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag caggtcaaat
    36121 tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa gacaaccgaa
    36181 tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag ctggttgctt
    36241 ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa tctatcaaag
    36301 aacaattact agaagttgta atggattata tgattcctca gaagttccat tatgtcgatc
    36361 tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct gaggtgaatc
    36421 ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt ttcttttagc
    36481 cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat taccagttta
    36541 tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt attggcaaca
    36601 gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg gctattttgt
    36661 ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt tagcgataat
    36721 tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat cgttacttgg
    36781 ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg aaataagaga
    36841 tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt tctttccaac
    36901 aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc tccatccgcc
    36961 tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt ttgtcggttt
    37021 tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg tagtgggacg
    37081 cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt acgtgtacag
    37141 tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta caagctacat
    37201 gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga atatcaaaga
    37261 attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg tatatatgcg
    37321 attgatgttc ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa tgtcaaatat
    37381 cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt ggtactacat
    37441 cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga tccgatttaa
    37501 gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag ccgtattttt
    37561 gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag ataaactttt
    37621 ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag gaaaatggaa
    37681 gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag aaaaaatcgt
    37741 gatattgatc tatttgatga agggttgctt gattctttag catctgttca attattagtc
    37801 gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg agaggattgg
    37861 tgcacaccga ataaaatcat tcaacaagca actgcattga agggttgagt atgaaaaaga
    37921 aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt gtgtttttta
    37981 cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc tcttcttcca
    38041 tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct gaaaaacaat
    38101 atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat ccgtctgttc
    38161 tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc gggacacaat
    38221 cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac aagaaagtcg
    38281 tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat tactttaata
    38341 cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa gtaacgcctg
    38401 ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag aatgatacgt
    38461 tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa tctttgaatc
    38521 agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc aatattgggt
    38581 tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa caataccaag
    38641 aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg aataatccat
    38701 tcgggttgaa aaacgatttt tatacgcatc gtatccgagc ccacgagcca gagctcaaac
    38761 agtcacaaaa aaattgggat tatcgttttt cgccagaatt ttctgatttt cagctggtct
    38821 tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg gttaacgaga
    38881 aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc aaaaagatca
    38941 aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat caagcgggta
    39001 ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg gctgcagatc
    39061 aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat catcttgacg
    39121 atgctttttt tagcaaatct tggcaacatc aaataccaga taaactacaa ttaaaataaa
    39181 gaaaacaggc gagtgttgct cgcttgtttt ctttattttt gaatattctg aataaaagat
    39241 aaaaatacca agtttgcctg aacaaaaatc ataagcaatg gtataatcac aatatgaata
    39301 tagaaatggg ggaaaacatt tggatacaaa agaagaacag ctacttattg atttaacttc
    39361 tgcaaaagga gtacctggaa atgaagaaga ggtaagagaa gtattcagag aatatgccaa
    39421 accattcgct gatgatattt tttatgacgg tttaggcagt gtgattgcca aacatggtgc
    39481 tggcggaggc cccaaggtct ttatttctgg acatatggac gaagttggtt ttatggtaac
    39541 aaaaataacc gaaaaaggat tcttggaatt ccaaactctt ggaggttggt gggggcaagt
    39601 catgcttgct cagcaagttg aaatcaaaac acgtgaaggg aaaatcgtcc acggtgtgat
    39661 tggttccaaa ccaccacatg ttttaacacc tcaagtaaga aataaacctt atgaaataaa
    39721 ggatatgttc attgatattg gcgcatcaag ccaagaagaa gccaaagagt ggggcatacg
    39781 tcctggagat atggtcactc catatattga atacaaacga atgaatggca gtaaatattt
    39841 actggcaaaa gcatgggata atcgtatcgg gacagctgtt tctctgcgag tattagagaa
    39901 tctatctaaa gaagcacacc caaatgtttt attcgcagga agcgatgtgc aagaagaagt
    39961 aggcttgcga ggtgctcgaa caagtacaca ccttgtaaat cccgatattg cttttgcttt
    40021 agatactggt acagcaggag acactccagg aatgacacca aaagaagcag attcgatttt
    40081 aggaaaaggc ccacagattt tgatttttga tgcatctatg atcccgcata aaaaattatt
    40141 gaattttgtt attgatgtag cagaggaaat ggatattcca ttccaatata cagtgatttc
    40201 tggcggagga actgatgcag gacaaatgca tttgacaaga gatggtgttc cgtctgtagc
    40261 cattaccgtt cctgttcgtt atctgcattc ccatacatca gtgattcatg aagatgatta
    40321 tttgaataca gtgaaactag tcacagaatt agtgaaacgg cttgatagtg aaacagttga
    40381 aaaaattcgg agttatgaat aatgaataat agaataccta tttctgaata tcggaaaaaa
    40441 gcacgagttt ctttggaaaa tcaatgggga atcaatactt ggcttgtttt cttatctata
    40501 atatttacga gcgtcatcca gaactttttt gacggtttca gtccttttcc ggaagaaagc
    40561 atgcagcagc acttattgag ttttctagtc gataatttac ttttattcgc attcaactat
    40621 gcattgtttt acattgcgct agtagttgta cggggtggca gaccaaaaag taacctttta
    40681 ttttcagttt tccaaagaaa gtattttggt tcgatacttg gcatcaattt gatcaattca
    40741 gtcatcaact ggctactcaa cagtttaatc tttctgccca tgtttttaat cagcggagtg
    40801 agtacttata tgcagctgct tttcagttca aatgcggtac ctacgggtgt catgccagaa
    40861 gattttcttg atatcagctt tgttttatcg atgataggga tgatttttgt ttcagcactc
    40921 atcatgagta ttgttggcgg tttattccaa tttgctgcat ggacaaagtt cgactatcct
    40981 gatttgtcgg ttattcaatg tttgaaatat ggctggtttt tattgaaaga tagaattggt
    41041 acgtatattt tgttgcagct gtcttttatc ggctggtatt tgctaggagc aatcgctttg
    41101 ttcatcggtc ttttgtgggt cattgtttat gtgaatgtgt cagttgcaga attttatgaa
    41161 caagcacgga ttgaaaaagg aggtccagac gcctatttta cttagcatgt aagcagttta
    41221 ttcatcaaaa aaataacttt tgtggtagga taaatctttg agggggaatg tacgatgaaa
    41281 ttaactgttt taggatgctt aggagcgtat ccttataaaa atcaagggac aacaggttat
    41341 ttgcttcaat ctgacgggtt caatttgttg atcgatgcag gtagtgctac gctgatcaaa
    41401 ttacaagaac accttgatcc acttgatcta gatgctgtga tccttagcca ttatcatcat
    41461 gatcatattg ctgaccttgg tgtattacag tattactggc aacttcatcc taagagaaat
    41521 ccggagacat tgctttcaat ttatggacac acaaaagatt ccattcactt tgaagaattg
    41581 acgttggaaa atgtctcaaa aggacatcct tattttgaag ctgaagaatt aaaaattggt
    41641 ccttttctga ttacttttat ggaaacaatc catccagtag tatgttacgc catgcgtatc
    41701 gtagaagaaa caacggggaa agtattcgta tttacaggtg attcaggtta tttggaaagt
    41761 ttcgctgatt ttgcgaaaga tgctgatttg tttctagcag atacctatct ttttgaagga
    41821 aatgaacatc atcatgccca tttcacttca aaagaagctg gagaacttgc gaaatcagct
    41881 aacgtaaaga aacttgtact tacacaccta cctcagtttg gtgatttaga acaattgaaa
    41941 aatgaagcgc aaaaggcagc aggcaaaggg attgatatag aacttgctgc agttgacaaa
    42001 gtgtttaaca tttaggagga agaacatgat ttttgtacca aatgaaaacc acgacccaag
    42061 aatcaattta gcaattgaac aatatttgct gcaagaaatg cctttagatg aacctatttt
    42121 gctcttttat atcaatgaac cttcaatcat catcggcaga aaccaaaata cgcttgaaga
    42181 aatcaatcga gattatgtgg aagaaaatgg cattcatgtt gtccgtcgct taagtggagg
    42241 cggagctgtc taccatgatt ttggaaacct gaactttagt tttatcatgc ctgatgatgg
    42301 ggattcattc cgtgactttg cgaaagtaac acagccaatc atccaagcac ttcatgaatt
    42361 gggtgttgct ggggcggaat tgaaaggccg aaatgatcta gtcattgatg gcatgaaatt
    42421 ttctggcaac gcgatgtatg ctaccaacgg tcggatgttt gctcatggaa caattatgtt
    42481 cgactctgat atcaatgaag tagtcaatgc attaaaagta aaaaaagaca aaatcgaatc
    42541 aaaaggaatc aaatcgatcc gttctcgtgt aacgaatatc aaaccatttc ttccagaaga
    42601 aaagcaaaaa atgacaacag aagaatttcg tcaagaaatc ttgttgaaaa ttttcggcgt
    42661 agagtcagta gaagaagtaa aaacgtacga attgactgat gaagattgga aaaaaatcaa
    42721 tcgaatctct gaggaatatt atcgaaattg ggattggaat tacgggaagt ctccagattt
    42781 caatttctct cgccaaaaac gtttttctat cggttcgatt gaagtccatt tgaatgtctc
    42841 agaaggaatg atcaaagaag caaaaatctt tggcgatttc ttcggactag gagatatctc
    42901 tgacgtggaa aaaaaattgg ttggacagaa atatgataaa gcatctctat caaaaatagt
    42961 cagccaaatt gatgtgaaga aatattttgg tgcgatagaa ccagaagaat tgcttacctt
    43021 actttattga aaataaaaaa tagcggaatc cacatatatg gattccgcta ttttttatac
    43081 aggattcggg taatttcgag agagttgaac agtgatccga tcaatgaaag tatctttttc
    43141 ctgcgttagt gttcctgtgt aacgatccgc tacgtctttc atcatcatta agtcaaaacg
    43201 ttcctgatca tctaattctt ctgtgatgcc tcgactaaat aggtttgtat cgtaatgtgc
    43261 actatgttcg caacaaatga cgaaatgttc ctcttgttcg tgtatcgaca aataaatttt
    43321 tcgatacagt ggattttcga tggcatgagt ttctctaaag gaatgctcta aagcgtggat
    43381 caaaagttga gccagatcgt catcgttgat aggaagttct tcgggaagat ctgcttggaa
    43441 ggttatctga atattccgtt tggcagctaa cttctggtaa cgcgctaaga taagatttgt
    43501 cacctggtgg ttgcaaaaag aacacagcat ttcgaaattt tttgcttctt ctaatatctt
    43561 ttccacatag tttttagctt ttgtttggtc cgtatgcatt aaatcttgca gattctccat
    43621 ctcttggaca aattccaggc gaagtgtatt tacttcttgg atatgctgtc gaagctgctc
    43681 ataatgttgc tccaacaaat catttttgat ttttaagaaa tctacttgtc tccgatcttt
    43741 gtcggtattt aagatgtgat cgattagatt gtagctgata ataacgatta gaatgataat
    43801 atataaaatc gtagaccaat tgatcgttgt ttgatagata cctaatgccg tttggatgta
    43861 aatcaagcaa tggataatgg ctaccaagac gatccaaggt gtacaagcta cataaaaacg
    43921 gttattctta tatgcttcgc caatgcatgc aagtgaagtg actaaagtgc ttataacact
    43981 agcaatatta gcaatcggca ttaattcagg aagttctgca ggagtaaaag ttgcataaag
    44041 cagaacgccg ataaaaatca aaagttggaa cgtacaaaaa attccgtacc attttttata
    44101 gtaaaacatt cggctccaat agtagcagat gatgaaagct gacgttaaga taataaataa
    44161 atgagataaa aaagaatgaa cgaatggttc aaaaagaata ccacttaaaa tatcttctga
    44221 tacagcttca aatcctaatg ccaaagcaaa gcaacttaag agaataagtg agtattcaag
    44281 acgtttttgt ttatacatca agtagatcgt atagaaaaag gtccctatag cgataaaaac
    44341 agcgattatc atcgtcaata cttgcggcac tgattgtgaa taaataaaac taatcaatgg
    44401 tccagttgtt cctagataaa ctttcggtgg cagtccagca tagttctgat aaggagatga
    44461 gactgtaagg gtcaattttt ttccgatata atttgctggt aaatctatca cagccaatga
    44521 gagtccggga ttgctttctt cctgataatc tttccgttgg tataaaatct tttcgcctag
    44581 atatacagta atccattgat ggtttccttt gattagtaaa tttgcttcgt ccaacggttt
    44641 ttcaagtgtc gtttccataa tgaatgtttc gtctttatcc acggtaggaa tcgtacgagt
    44701 gtacttgctg tcaaacttaa aatcaggatc atcttttgta tagaaaaccc acgaatcttt
    44761 tatttctttc atttgattgc tgtccgcagg agaaaaaata aaataaaaga aataagcaat
    44821 tcctgttaaa aataacaatg ataatataat gattatgctc cactttatac gtaaataaaa
    44881 agattctttt ttattatata tgttattaaa aaaagacata aaggtattcc tttctaaaac
    44941 ttgtaatgtt agggtaaacg ttttttaaac taacgtcaat tatttataat aaaaaatgag
    45001 ataaagatga ggaaatagaa ttagaaacat ataattatta aagggaaaca tttttacagc
    45061 tataatttga aaaaaattta tcgttattat atgattaaga aggattgaat aaagaaagaa
    45121 gttgaaaacg atacctgatt acaaaaaaat aacttttata agttctataa cgttgattat
    45181 atttttaatt cttattcttc tcgtcgtctt ggttccccga atttttggtt tgactcctta
    45241 tattattgag gacaaagaaa tgagtccata ttatgcacaa ggaaatctga tatatgtacg
    45301 accgaaaaat acaaatgaga ttttagtcgg agatattatt acatattatg aaaattcagg
    45361 aaaaaaaatc tcgacgcgtc gcgtaatagc cgttgaaaac aaccacgaag atttttatac
    45421 aaaagctgat acaaagactt atattgagcc tggagtagta aaaaagagaa atattatcgg
    45481 tagtcccatc tttcagattc catatattgg actagtcctt tcaaaaacgg catttgcatg
    45541 gattcagggg ttattcttta cgattgcttt ttgcctaaca ggaatcacag catggaatac
    45601 ctttgtagag ttgaaaaaga agcggagacg aacacagaaa tttttgtaag aatgttaaaa
    45661 acataaatgt attccagaga tccaacgact cttctgaaca tgaaacacga gaaaacactc
    45721 atgcagcttg tagatttagt cagttgttcg tataatgtgt gaagaggagg agtagtatgc
    45781 gcaatgaaat gatgcatcgt cctgtagtca aagaagaact attggatttt atgcgtaccc
    45841 agcaaaaaaa attaccgggt gagctaggca aactggaaga agaagctcat gtagcagaag
    45901 taccagttat tccccatgaa acagttgtat ttttgaaatt tttacttgga cagcttcagc
    45961 ctgaacgaat cttggagatc ggagcagcta tcggtttttc atcaagtgtc atggccacga
    46021 caatcggaga aaacgctcat gttacgacaa ttgatcgttt cgatgtcatg atcgagaaag
    46081 ctaaaaaaaa ctatgaacgt ctaggactga cagataaagt gactttgctt gaaggtcaag
    46141 cagcagatat cttgccggag ttgtctggtc cgtatgactt tatttttatg gatagtgcaa
    46201 aatcaaaata tattgaattt ttacctgaat gcttacgttt gttaagaaaa ggtggcgttt
    46261 tgatggtaga tgacatcttc caaggaggaa cgatcttgct cccagatgaa gagattcccc
    46321 gtggcaaacg agctatccat cgtaaattaa atgaatttct tcgtgttgtg atggatcatc
    46381 ccgatttgac atcgacaatc ttgccattag gtgatggtgt gatcttaatg acaaaggaat
    46441 cagaaacaat cgagttgtga tacatgatta tggcagcctg tagataatcg attgaatcga
    46501 gggctcaatt cgaacttgat gtaaaagttt ctatatttgt aagtcaatta aaggatacag
    46561 gaaatctaaa taaacaggag tagcatgaag tcaatgtagc tcctgttttc aattgataac
    46621 cttagaacag ctgaaggaga atgtctcgtt ttaaaagatt gatttagtag ttgggccaaa
    46681 ataattcatt atttgctaat taaataacta tttcgtattg acagaagcaa tttaattatc
    46741 tataattatt gatgttccgc tgattcttgt catagtagct cagctggata gagcatccgc
    46801 cttctaagcg gacggtcggg ggttcgaatc cctcctgtga cgctaaaaaa ccgttagaaa
    46861 ctgaggtttc taacggtttt tctttgtttt ttgtgccaat attgtttgtt ttcaaaggca
    46921 aataaaataa aaaaacatcc ttatcgagta caattataag gagcaaaaaa ataaaactca
    46981 tcagaaaaga ggaagaagat atgacgatac tatctagaat tttagtgact ctagttgcaa
    47041 ttgaattttt ttatatcatg tatatcgaaa cggtgagaac tgattctgac acgacaagta
    47101 gggtttttaa aatgagtaaa gaagagttaa gcagaaaatc tgttcaaaca ttgtttaaga
    47161 accaaggagt gtacaatgga ctattaggag tgggactact ttatggagct tatctttctt
    47221 ccgcatctaa agaaatcaca agtatgctat taatatctat tttttttgtt gcattatatg
    47281 gcagtttgac tagcgatcgt tggattttac tcaaacaagg tgggctagct ctgttggcat
    47341 tgctttctat tttcttataa atatagaaaa aataagaatt tatctaacag gaaactttgt
    47401 gaaaaatatt actttatctc atgaaatatg atattctaat gaatggtatt ttagaaaatt
    47461 tcatgaaaaa ggagttagat aggtgttcaa aaattatgtt tcctcactaa aaaaagaatt
    47521 ttcaggttat gatctttcaa gatttcagaa agatcttttg gctgggatca cagtagctgc
    47581 tgtagcattg cctttagcct tggcttttgg ggtatcaagc ggagctgatg cggccgcagg
    47641 tttgattacg gctatcattg ccggtatcgt tattggcggt ttatcaggcg gtttttatca
    47701 aatatcaggt ccgacaggtg cgatggcagc tatcttgatg tctattgcgg caacaaaggg
    47761 aatgcaaggt gtattgcttg ctactttttt agcgggtcta tttttacttg cagcaggact
    47821 tttccgatta ggaacactga cttcttttat cccagcaccc gtaattacgg ggtttacttc
    47881 aggtattgct atcattattg cattaggtca gatcgataat ttatttggtg ttcactcgga
    47941 aggtacaaac gttattgaaa aactaagtag ttatcaaacg ataggatttc cgataaacac
    48001 agcctctttg atcatgggag ggctagtcat tttagggatg tttatctatc caaaaaaatg
    48061 ggcgaaacga atgcctagtt cgctgctggc tatcattttg gcaacagcag ttatgctatt
    48121 gttccattta ccagtagcaa ctgtgggtaa gattccacaa acattgatca gtagtaatcg
    48181 tttgaatatg ggagatttta gcttttctgc cttgcaacaa gtggcagttc cagctattag
    48241 cattgcttta ttaggaatga ttgaaagctt gctatgtggt gcttcggctg gccgaatggc
    48301 aaataagccc ttagatagca atcaagaatt aatggcgcaa ggaattggaa atctgttgct
    48361 tcctttcttt ggcgggattc ctgctactgc ggccatcgcc cgtacaagcg tggccatcaa
    48421 atctggtgca caaactagat tagctggtat gatacatgca gttgtcttac tgctctccat
    48481 gcttgttttt gcgccagtga tgtcacagat tccaatgcca gcacttgcag gtgttttgat
    48541 tgtgacggct tggcgtatga atgaatggga aacgatcaag gagctattta ctaataaata
    48601 ttggtcagca gttctattgt ttatccttac gatgatttgt acagttatct ttgatttaag
    48661 tattgctatc gtgatcgggg tgatcggcgg ctgtgtattt tttgttgtca aaagcgctgc
    48721 tatcacgatt tcattagaaa cgatcgattg gcaaagaatg gggctgccag aaacggaaaa
    48781 gctgaataac tggacagtag tgtatattag tggtccactg ttttttatgt cttcagaaaa
    48841 actcaaaaat aaattggaag aactaaatca tcacgatggt gtcattttct ccatgcgagg
    48901 cgtaccaagt attgatttga cggcacgtgc agtttttgat gaatttcaag aaaaagcaga
    48961 gcaaagagga caaacgatta tctatacttc cttgcagcca gaagtagaaa aacaactttc
    49021 tcacttgtgg gaacatacat tcacgcatca acatcaaaca gttgctcatg cgttgacagc
    49081 tttacatgcg aaatatactg caattagcca ttaaaacaat gaaaaagaac agacaagact
    49141 gtaaactgaa gattttatgg tcttgtctgt tctttttaat attgctgtaa aagtgaagct
    49201 agtacttgcc agtcttgatg gataacaggt acaagggagc gattgtagaa aatagctgct
    49261 ggatgaaaaa gtggaagaat tcgatagttt ttttctgacc attcgtaggc atccttttgt
    49321 tctgttaatt gtaagacagg ccctgtatag agttgaccat gatttttggt aaccgtatat
    49381 tctttgccaa gtaaacgttg aagaccaatg tttccaagtg tcgcaattaa ttttggctgg
    49441 accttcatca gttcgtaatc caatattggt gcatgcgcaa atacttcgga acgagtaggt
    49501 gtccgatttg gataaacagt ttctgactgt tgtgtccgtt tattgatccg atgagtcacg
    49561 cgatacgggc ggctccttac agcactggtg atatacacct cttctcgtgt taagccagtt
    49621 gaagaaagtg cctgcatcaa ttcttttcca gcttgaccgc taaaaggaac atgcgtatca
    49681 atctctgttt tccctggggc ttctcccacg agcatcagtt taggatgaag aggtccttgc
    49741 ccagcgataa atccttctac aggacggccg ttcattctta aagaagcttc ttgtatcagt
    49801 tcttttgggt attccattta tgctcctcct ttttctttta ttataagaat aaaagaaaca
    49861 caatgcgact attttatttg gtagaactgt gaggatagaa aagcagaagt attgcttgaa
    49921 tttttgtttt actttttgat tttaaattta gttgactaac ggttgctgtt ctggtaagct
    49981 agtactgttg taattgtgga ctccacagct acaaccgctc agaacaagta ataagcacag
    50041 catatgctgt cacttcggat ggcgagtcta agtatatcag aaggaggtgc tttatagcat
    50101 gtacgcaatt attaaaactg gtggtaaaca agtaaaagtt gaagtgggac aagcaatcta
    50161 tgttgaaaaa cttgacgttg aagcaggaga aaaagttgtt tttgacgaag ttatcttagt
    50221 aggcggagaa tctacaaaag taggcgctcc aactgttgca ggtgcaactg ttgaaggtac
    50281 tgttgaaaaa cacggcaaac aaaagaaagt cgttactttc aaatacaaac ctaaaaaaca
    50341 ttcacaccgt aaacaaggtc atcgtcaacc atatacaaaa gtggttatcg acgcgatcaa
    50401 cgcttaatag cgtttgagaa agaaggccta tatatgatca aaggaacatt taagcgaaat
    50461 gacgcaggtc agatcgtttc attcactttg accgggcatg ctgatgctgg tccttatgga
    50521 agtgatatcg tttgtgcggg tgtttctgcg ttagcgatca gcactgtcaa cgggattgcc
    50581 tcattagccg gttttgagcc gattgttgaa atgaatgaag aagaaggcgg ttatctttat
    50641 accgaagtca cttcaggaat gacacaagaa caaaacaata ttgctgagat tctattagaa
    50701 aatcttttat taggattaca atcgatagaa gctgaaaact cagaatatat ccaaattaaa
    50761 acaattaatg ataaatagga ggtgcagacc atgttgttat ctatgaatct acaattattt
    50821 gcccacaaaa aaggtggcgg ttctacatct aacggccgtg actcagaatc aaaacgtcta
    50881 ggtgctaaac gtgctgatgg acaaacagtt acaggtggat caattcttta ccgtcaacgc
    50941 ggtacaaaaa tctatccagg tgtaaacgtg ggtatcggtg gagacgacac tttatttgca
    51001 aaagttgatg gcgtagtacg tttcgaacgt aaaggccgta acaaaaaaca agtgtctgtt
    51061 tatccagtag ctcaagaagc ttaataaata aactgctcta tctcttgtgt agcaagggat
    51121 ggagcttttt tgtaaattat gggatttttt ttgaccatac ttttgaccat actttcttag
    51181 aagttaatat aatttgttag tttttgtgtt gtttcttctt ttttgctgtt agtaatgtgt
    51241 gtatatgtgt ccatagtagt ttttatattt gcgtggccca ttctttcttg gacttctttg
    51301 tgatctgcgc ctgcctcata tagcattgat gcatgtgtat gtctaaaacc atgcagaccg
    51361 atataaggta agccggcacg ctcacgatat atattgtatc tttctgccac tgactgatta
    51421 attgtgaaat tattttcgtc attggtaaac aaataattag ctttagtaaa tcctaattga
    51481 aataagtact ttctttgttc gagcttccaa aattttagtt gctttatagt tttttcatct
    51541 aaataaatta ttcgatttga ttttttggtt ttaggagttt cagatatata atatttatct
    51601 gaacgagcta cagttttttt aatggccatt tcatttgttt taaaattaat attgtcccaa
    51661 gtgagtgcta atatttcgcc gattctacat ccgctgaatg ctaatagtct aaagagcgta
    51721 tagtctctgt ttttaaaata tggattctgt tcttgagata cttcatttag aaataattcc
    51781 aactgttctt ttgtatataa ttttaatttc ttttctgttt taatttgtgg ctttggaata
    51841 agtaaattta atgttggatt atcagatgtt aaaccaatat ttatagcata cttaaaaact
    51901 ttattcatat agtttatgaa aagagggtac tgctttgaag ttcctttttc actccaatca
    51961 tttactacct tttgacaata tgccgtatta attttagaaa gcttaatatt tccaaatttg
    52021 ggatatatat gtttattaaa gattatttta gtccttgaat atgaactttc ttttacagtt
    52081 tttttgtagc tttctagcca taattctgct gcttctttga aagtagtatt tgtacttgtg
    52141 ggcattcctg ttttttgtaa ttctagttct aacctagaaa gtgctgtttt tgcttctttt
    52201 tgtgttctaa atcctcgttt agtagtatat tttttctttc cagttagcgg atcaataccg
    52261 agataagttt taaagtacca tgctttttcg ccatttttct ttttatattg ttttatcatt
    52321 gccatcaata ttacccctat tcaaattcta attctgccat gctatcattg aaaaattcga
    52381 tcagtccttg ttcctctata aattcaagcc atatttcctt cccgttaatt aatggaactc
    52441 ctttttcttt acgaattgtt tgatacaagt tagtcacgac ttgtttccac atttctaata
    52501 cagctttatc tattttctta tcatcccagc gttttttttg gggtctattt ttgttttttt
    52561 caatttgata attagtagct ttgatgataa atgtttcgta tccggttgtg cttttttcta
    52621 accattcttt gaattctgta tatatcattt ttgttcacct ttctattttt gaacgtatgt
    52681 tcttttttgc ttaaaaaatt ttagagagct gcataacaat agatgcgagc ttttaataat
    52741 tctttcacaa gtggttcgaa gcgaacgctt aaattgttat cttctataaa tttcatgtaa
    52801 ttgatattgt gtggttctaa ttcagacttt gcaatatatc tatctaataa tttttcaatc
    52861 atgaagcgat cagcctcata ttccattttt gaatggagag agaatgctaa gttatataaa
    52921 aaataattat catgatgttt agaagcgtgt cctaattcat gtaataaggt tctttgtctt
    52981 ctatacttag ataaattagc ttttattact atggtattca tacaagcaac ataatggcca
    53041 tcggcatcaa ggttttcacg ctcttctacc ttaacgccga gttcattaat tatcatttca
    53101 atttgactgt ccaaatgact cacctactta tttagttatc ttttttctct aaatatgctt
    53161 caatcatagc tgatagtatt tccctatcat tatcggtgag cggttttccg tcgctactca
    53221 taacagatgc taaagcttct tccacggtta gttttctttc ctctggtgca actcccgcgt
    53281 taggatcatc tgtgcgtcct agcaaataat ctgttgatac atggaagtag tcagcaactt
    53341 tttgcaaagt ttctatttta ggactttgtg tcttccattt ataaatagag ttttttccaa
    53401 atcctattct attttctaat tcagaaatag aaatacctct ttttttacag agctctttaa
    53461 ccctttcgaa aagcatgtca aatcaacctt cctagagcgt acgataataa tttatacaaa
    53521 aagatagaaa ggtagttgac aaatctatcc aattgtctta tatttaactc gtaagctaat
    53581 ttaataagct aacaagcaac aagaaataca cctaataaaa taaacgaatt cgaggtcggc
    53641 aaactaagaa tgttaatttt tagggttttt ctaggcttat ttaactgtat ataaatataa
    53701 gacagttgga tagaaatgtc aataaaaatt agctaatttt attagcttac atatttaaag
    53761 aaaaggagga aacatcatga aacaaaataa aaaaactcct tccgcaaaag gagctttaat
    53821 aactttaaat tttaaagacc aaaagtttag tgctgttgtt gatgaaattc atccacaaga
    53881 gcatcaaaaa aattcttttg caactgacga gaaaaagact cagaaacgct ctgagaaagt
    53941 tcttcgaata attcaatttc tgttggaaaa gattcgtcat tttggaagtc tattttgaat
    54001 tctttattaa cagtcttgaa tacggtttgt ttgaataagg cgtcgacatc catattaaat
    54061 tcttccatac tattttcacc tcgctttcta ttcaaaatta tatcaaagaa aggaatgagc
    54121 aaaaatgaac acaccgcaaa tttttaactt tgaacaacat gaagtaagaa cagtaacaat
    54181 acatgatgaa ccattttttg ttggaaaaga tgtggctaaa gttctagggt accaaaatgg
    54241 tagtagagat attaacagac acgtcgatgt agaagatcgg caaaactacc aaaacggtac
    54301 ttttgaatcg cctagagggt taactattat taacgaatca ggtttgtact ccttaatttt
    54361 aggaagcaaa caaccaaatg ctaagaaatt taaacgttgg gtgactagcg aagtgttgcc
    54421 agcaattaga aaacatggag gttatctaac tccagaaaaa gtagaagaag ctttgcttaa
    54481 tccagataca atcatccaat tagcaactaa gttgaaagaa gaacgtactg gaagactaat
    54541 cgcagaacaa aaaattgcag aatacgaacc caaaatttcg tatttggata gtatcttatc
    54601 ttctacagat tcagtaacta ttagtcaaat cgcggctgat tatgggatgt ctccacaaca
    54661 gatgaacaaa ctacttcata agctaggtat tcagaaaaaa gtaggcaacc aatggttatt
    54721 atgcaaaaaa cacatgagac agggttacac aaaatctcat acaactgaga ttccgaaatc
    54781 tgatggcgga acaaaagttg tgatgaatac aaaatggact caaaaagggc gtctgttcat
    54841 ttatgagtcg ctgaaaaaag aaggatatat tccagaaatc gatttattag aggaggaatg
    54901 acgatgtcac aagaatttat tttgaaagtc agaattcaat tagcaaaata cggaaagtct
    54961 cagaactggt tagctgatac tatcggaatt tctagaccat atatgtcgga cattatgaat
    55021 gggcgtagaa aaccagataa acaaatcaag ccaattgagg cagcactagc agagttagag
    55081 aaggagaaat aacatgcaaa taacaattcc agataattta gtagtttccg aattaactac
    55141 acagattacg aatgctgttc ttaattcatt ggacgaacga ttacacctta tgaacaaatc
    55201 agtagagctt cctccatatc caaacaaatc agaggtaaaa aaagttttag gcattggtga
    55261 tgacaaatta acacattgga taagcctagg cttaaaaaca cagcagtgga gcaagttaga
    55321 catcagaatt gaacgatcgg aactccaaag atttttgaaa gaaaactttg agttctaaag
    55381 gcaaaggaga atgattttat gtcctacaca ttgcaacaag aacatcaaat tctaggtctg
    55441 attaaacagc gtagaaaaca attacaagat gatcgtgcag cgcttagaaa atccgatgag
    55501 ctatcagata gacaagctga actaattgct tctgaacttg aggatttgag aatgctagaa
    55561 ataaaaaata gggagattag attatgaaga agacagacac actttttata ggattcattt
    55621 tggggttatt agtgattgta gcgcaccaaa gtattatcgg aggaagcttg ttcgcagcat
    55681 tgatggtttt aatcaatctg cttgactcaa aagaaaggag caactatggc acgagaagaa
    55741 gcgctaaaaa tcggtaaagt gattgctgat aattggtggg caaatagccg ttctattatt
    55801 ttaagcaagc aacatatcga aaagaaaaaa gcatggcaac aaataaaaaa gtgactccgc
    55861 cgaccaaagc aatgagtcac tcaaaaaatc ataactaagg agattttaac atatggaaaa
    55921 tgaactttcc actctagatc aatatttggc cgatcctgat tggggcaaat cgaatttaca
    55981 actggttgct aacaagtacg aaaaatcaat tgatgaagca attgttgcat tgactgatgc
    56041 agcttccata accgctgatg acagtaaatg gaccaagaga gacttgggca ttctaaaacg
    56101 aggcgttaat tggcttgaag atcagtacag agaagaaaca aaagagaagt gatatgagtg
    56161 tttaaaccac taatagattc atactcggcg gtactaaaga aatttaaagg taacgacatt
    56221 ggtgcaacaa tcaacgaaga agtaaatatc gaacggctga aaacgatgta tgacggatat
    56281 gatggcgatc gagtcattga aattcgcttt attgatccac gacggttcac agtacagcaa
    56341 agaaacttca tctatgcgct cataggcgat attttcatcg atacaggcat gccaacggac
    56401 ttctggaagg aattcttcta cttccgtttt gaaggtgtca cagggcgcga aataagcctc
    56461 aaagacgaat cgaatacaac cgtgagtgat gccaatatct tagcgaatat catcctagat
    56521 ttcatctttg aacatcatat tcctttcaaa gaaggatatg agattttacc agcgaatcaa
    56581 gagtattact tctacaaatg cattacaaaa agagtctgct gcatctgtgg caaaacagga
    56641 gctgatatcg atcactttga caaagcgctg ggaagacgaa agcgcaaaga agttgatcat
    56701 tcagagtaca catttgcagc actctgcaga atccatcaca cagagaaaca caaaataggt
    56761 gtgatcaatt tcaaaaataa atatcaaatc aaagggatca agttaaacca ggaaacaatt
    56821 aaaaagttaa ggataggagg ataaatttgg ctgagataag ttggatcaaa cttaaaacta
    56881 ctatgtttga cgatgaaaaa atacgattaa tccaagctgt tcctgagtcg gatgccatca
    56941 tcgttatatg gattcgatta ctagttttag caggaaagac taacgacgat ggtctgatat
    57001 atatccagag gaacatgcct tataccgaag aaatgcttgc tacattgttt ggcaaaaacg
    57061 taaatacggt tcgcttagcg ctaactacat tggcaaattt caacatgatt gatctaagca
    57121 gtgatggact aattgccatc agtaattggg aaaaacatca aaatatcgag ggtatggata
    57181 aagtaaggct aaaaaatgct gaaagaaacc gtaaatacag ggaaagaaag agacaggaac
    57241 gtctcaaatt ggaaaatgac gttagcgtga cgtcacgtga cggtacagat aaagatatag
    57301 aagaagataa agatatagat aaagaagaaa agaaaggtaa gtattctgac gaacacttac
    57361 gccttgctaa aaagttgcaa agtaatttaa ctgaagattt tccaaaagaa atgaacaaag
    57421 tagatatcga aaaatgggca gacacaatca ggttgatgga agaaagagat aaagcatcta
    57481 tagaagcgat tgagtatgtg atcaattggc tacctacaaa tgaattttgg tttggaaata
    57541 ttagaagtgc taagaaattg agagaaaaat ttgagaagct caaattcgaa atcaaagcag
    57601 acaagaagaa tcataaaaag caaagtcaaa aactacagta cagcaatcct agtgaatatg
    57661 acgacttgcc aatttaaaaa ggagatgcat cacatggaaa gcctagcaaa tgctatggag
    57721 aaactaataa gaagagtatt agtgcaaagc ggaaaatgtc cagaatgtag cgaacctttg
    57781 tatagttggc gagctaaaaa taaggatggt tcagaacgtt gtaaaccaac atgcatgagt
    57841 tgtggttata aagcgttacg tgtgaaagag gatatacaga ccgaacggat atataacgat
    57901 agcttaaaag cacgagcgtt gagttttttt caaaatggtt cggtattaac agataaaact
    57961 ttgtttaaat gcaaaatgga aaattatcac gtagtggatc aagaaacaaa aatcgcttta
    58021 gaaaaagcaa aaagctatac gaatgaggtt ctgctgaacc atcctgcaca tttcattcta
    58081 tcagggaaat caggaagcgg aaaaagccac ttatcaatgg ccacagcttg ggaaatactt
    58141 gagcgctcaa attatgacaa gaaaatactt tttataagct atcaagaatt attagagcaa
    58201 ataaagtttt cttataacaa tactgaactg agaaaagaaa ttgaaggatc gcttatagcc
    58261 gatattaaaa caactgattt ggtggttttt gacgatattg gagctgaatt aggtagtggg
    58321 gtatcaaata gtaggcagtt tacaaacaac acgttaaaca cgctcttaga agccagacag
    58381 aacaaggcaa cgatcatcac aacaaactta tctggtcctg aactaagaga agcctacggt
    58441 gaaagaattg tttctaggat atttaagaat tcagaaggtt atgcgctgaa attccaacaa
    58501 acagcagaca agcgcataaa accagtgaaa ggtagtatcg catgaataaa taccgtaata
    58561 aaaaaactgt tcatcgaggt atcaagtttg attctatcgc agaagcagag tattacgatc
    58621 tagccttgtg gcaagctgaa gcaaatggct ggaaagtaaa acttcaggaa agatttgagc
    58681 tgatgccgaa atttgaacta gacggaaaga agtatcgcaa gatcgagtat attcccgact
    58741 tcacatttta taaaaacggc aaacttgtca aagtcgtaga tgtcaaagga atgcagacaa
    58801 aagactttaa gatcaaggca aagttgttct gtcatcaata tcaagcgccg ttgatattag
    58861 ctaaaaaata tcggaatacg ttcaaggaag agcgttttta acgaggtggt ccatcatgac
    58921 aacagaagaa gtgattcaaa tgcgtattcg aaacattcag cgtgaaattg acgatctaga
    58981 acgaacaaag gcagtgatgg tcaatgaaac ggcgagaaag gcaatcgatt tgcacataga
    59041 gaacttaaga agggaaattc gtagattgga ggaatgagcg tggataagaa agcgacaatg
    59101 aaacgaattg ctgaattaac caagtcagaa tcttggcagg aagacaaaga aatagttgca
    59161 gaagtccaaa agctcggtaa atcaatgtgg actgaaaagc ctaaacggaa aacgccgaga
    59221 aaaattgcaa tctggcatgg tgatcgaatt ctagtaacag gtacagctga acagttatct
    59281 gaaattactg gattaagcaa aaacattatc tgggatagag ctaggagctt atggattgat
    59341 tcaaaaggac gacagtttag gtatgtggag gagagataat ggatctcatt acacaataca
    59401 gtgacatcat cctcaagaaa atcatgatga agattcagaa aga
//
LOCUS       DAFENC010000013        59056 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.013, whole genome shotgun sequence.
ACCESSION   DAFENC010000013
VERSION     DAFENC010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59056
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.013"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(441..1751)
                     /locus_tag="LP493_001087"
     CDS             complement(441..1751)
                     /locus_tag="LP493_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBL2133249.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1763..3181)
                     /locus_tag="LP493_001088"
     CDS             complement(1763..3181)
                     /locus_tag="LP493_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2133250.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3421..4989)
                     /locus_tag="LP493_001089"
     CDS             complement(3421..4989)
                     /locus_tag="LP493_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBL2133251.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4993..5403)
                     /locus_tag="LP493_001090"
     CDS             complement(4993..5403)
                     /locus_tag="LP493_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HBL2133252.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5400..6323)
                     /locus_tag="LP493_001091"
     CDS             complement(5400..6323)
                     /locus_tag="LP493_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HBL2133253.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6320..7198)
                     /locus_tag="LP493_001092"
     CDS             complement(6320..7198)
                     /locus_tag="LP493_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HBL2133254.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7185..8522)
                     /locus_tag="LP493_001093"
     CDS             complement(7185..8522)
                     /locus_tag="LP493_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBL2133255.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8525..9628)
                     /locus_tag="LP493_001094"
     CDS             complement(8525..9628)
                     /locus_tag="LP493_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBL2133256.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9702..11210)
                     /locus_tag="LP493_001095"
     CDS             complement(9702..11210)
                     /locus_tag="LP493_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBL2133257.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11176..11868)
                     /locus_tag="LP493_001096"
     CDS             complement(11176..11868)
                     /locus_tag="LP493_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBL2133258.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11890..12864)
                     /locus_tag="LP493_001097"
     CDS             complement(11890..12864)
                     /locus_tag="LP493_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2133259.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13164..14036
                     /locus_tag="LP493_001098"
     CDS             13164..14036
                     /locus_tag="LP493_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL2133260.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14494..16692)
                     /locus_tag="LP493_001099"
     CDS             complement(14494..16692)
                     /locus_tag="LP493_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2133261.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16924..17916
                     /locus_tag="LP493_001100"
     CDS             16924..17916
                     /locus_tag="LP493_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2133262.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17976..19397
                     /locus_tag="LP493_001101"
     CDS             17976..19397
                     /locus_tag="LP493_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HBL2133263.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19390..20889
                     /locus_tag="LP493_001102"
     CDS             19390..20889
                     /locus_tag="LP493_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HBL2133264.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20928..22322
                     /gene="uxaC"
                     /locus_tag="LP493_001103"
     CDS             20928..22322
                     /gene="uxaC"
                     /locus_tag="LP493_001103"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBL2133265.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22481..23164
                     /locus_tag="LP493_001104"
     CDS             22481..23164
                     /locus_tag="LP493_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HBL2133266.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            23166..24002
                     /locus_tag="LP493_001105"
     CDS             23166..24002
                     /locus_tag="LP493_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBL2133267.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            24013..25767
                     /locus_tag="LP493_001106"
     CDS             24013..25767
                     /locus_tag="LP493_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2133268.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(26043..26384)
                     /locus_tag="LP493_001107"
     CDS             complement(26043..26384)
                     /locus_tag="LP493_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBL2133269.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26452..28623)
                     /locus_tag="LP493_001108"
     CDS             complement(26452..28623)
                     /locus_tag="LP493_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBL2133270.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28792..29691
                     /locus_tag="LP493_001109"
     CDS             28792..29691
                     /locus_tag="LP493_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBL2133271.1"
                     /translation="MVQLVCDCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            complement(29762..30619)
                     /locus_tag="LP493_001110"
     CDS             complement(29762..30619)
                     /locus_tag="LP493_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL2133272.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30604..33306)
                     /locus_tag="LP493_001111"
     CDS             complement(30604..33306)
                     /locus_tag="LP493_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBL2133273.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33319..34608)
                     /locus_tag="LP493_001112"
     CDS             complement(33319..34608)
                     /locus_tag="LP493_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HBL2133274.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            34758..35804
                     /locus_tag="LP493_001113"
     CDS             34758..35804
                     /locus_tag="LP493_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2133275.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            35806..37959
                     /locus_tag="LP493_001114"
     CDS             35806..37959
                     /locus_tag="LP493_001114"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HBL2133276.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(38432..39883)
                     /locus_tag="LP493_001115"
     CDS             complement(38432..39883)
                     /locus_tag="LP493_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2133277.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(39880..41604)
                     /locus_tag="LP493_001116"
     CDS             complement(39880..41604)
                     /locus_tag="LP493_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBL2133278.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            complement(41597..42211)
                     /locus_tag="LP493_001117"
     CDS             complement(41597..42211)
                     /locus_tag="LP493_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBL2133279.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            complement(42556..44013)
                     /locus_tag="LP493_001118"
     CDS             complement(42556..44013)
                     /locus_tag="LP493_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL2133280.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            complement(44054..44974)
                     /locus_tag="LP493_001119"
     CDS             complement(44054..44974)
                     /locus_tag="LP493_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL2133281.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            complement(44986..45933)
                     /locus_tag="LP493_001120"
     CDS             complement(44986..45933)
                     /locus_tag="LP493_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2133282.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            complement(46412..47131)
                     /locus_tag="LP493_001121"
     CDS             complement(46412..47131)
                     /locus_tag="LP493_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBL2133283.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            complement(47180..48826)
                     /locus_tag="LP493_001122"
     CDS             complement(47180..48826)
                     /locus_tag="LP493_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBL2133284.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            49005..49595
                     /locus_tag="LP493_001123"
     CDS             49005..49595
                     /locus_tag="LP493_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL2133285.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            49687..51192
                     /locus_tag="LP493_001124"
     CDS             49687..51192
                     /locus_tag="LP493_001124"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HBL2133286.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(51276..52628)
                     /gene="celB"
                     /locus_tag="LP493_001125"
     CDS             complement(51276..52628)
                     /gene="celB"
                     /locus_tag="LP493_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBL2133287.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(52628..53146)
                     /locus_tag="LP493_001126"
     CDS             complement(52628..53146)
                     /locus_tag="LP493_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133288.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(53162..53488)
                     /locus_tag="LP493_001127"
     CDS             complement(53162..53488)
                     /locus_tag="LP493_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HBL2133289.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(53501..55480)
                     /locus_tag="LP493_001128"
     CDS             complement(53501..55480)
                     /locus_tag="LP493_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBL2133290.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(55501..55815)
                     /locus_tag="LP493_001129"
     CDS             complement(55501..55815)
                     /locus_tag="LP493_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HBL2133291.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            55983..56276
                     /locus_tag="LP493_001130"
     CDS             55983..56276
                     /locus_tag="LP493_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBL2133292.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(56354..57466)
                     /locus_tag="LP493_001131"
     CDS             complement(56354..57466)
                     /locus_tag="LP493_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBL2133293.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            57853..58032
                     /locus_tag="LP493_001132"
     CDS             57853..58032
                     /locus_tag="LP493_001132"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133294.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            58226..58396
                     /locus_tag="LP493_001133"
     CDS             58226..58396
                     /locus_tag="LP493_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL2133295.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(58820..>59056)
                     /locus_tag="LP493_001134"
     CDS             complement(58820..>59056)
                     /locus_tag="LP493_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBL2133296.1"
                     /translation="DATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKH
                     LPKTGETIISQFILSILGVLLVFISIKFRKKRNI"
BASE COUNT        17713 a        12018 c        10312 g        19013 t
ORIGIN      
        1 ttgaatcaag acgccctaca catttggttt gtcttacttt gttcagtttt caaaggtcta
       61 cttcatcgag agtgtttccc gattcatttt tggctgccgt agcaactttt atatcatatc
      121 agagagacaa acgattgtca actctttttt aaaagttttt ttcgatttcg tttttcgaaa
      181 tctttcagca actcatttat cataacttat cgtttgttat ttgtcaagaa cttttttgaa
      241 gtttttttcg atagaatcaa gcttcgcaag tggttctttt taacgactta gttatcttat
      301 cacgtctaaa aacatgtgtc aactcttttt tggaattttc ataaaatgtt tcaatgaagc
      361 gcgacaacgt tgtttaatat atcattaaaa aaaataaagg tcaagctaaa atattattta
      421 agcttgacct tattataatt tcaacgattg tcaaaagtat tgtttgcagc tgtgttgcca
      481 gtttctatag ataaatcaca gcttttgaaa cataagtttt gtactgcttc gattcgcccg
      541 aattcttttg cagttatttg gcaatgagaa aagcagacat cttctatagg cttttcagga
      601 aatgctacta aatcaaaagc tcgggaagga agtgagtaac ctggagaaag gcatgcctgt
      661 acgtttttga tgtgtatgtc tttgactttc gtcatttgct ttgattcagg tatttcttca
      721 gccactgctt gccaactttc tggcatttga gcaaggtcat tgctattttt tctattgtat
      781 tcattatgcc agtccattat ccaagaaaaa ggaaattgta catcaatcat attcagattt
      841 tctaccctga tattttcgat cactccccct ctttcttttg aagatttcat tcgaatacca
      901 cagtctgact gaaaaaaatc gatatcgtga atatatacgt cactaactcc agcactaact
      961 tcgctaccaa tagttacacc gtatcctgaa cggattttac atctagcaac ctcgattctt
     1021 gatgattttc gattgactct tgcaccattg ccatctctgc cagacttaat agcaatacaa
     1081 tcatcaccac aggccaaatc acattcatag acacgcacat ttgttgaaga atcaatatca
     1141 atcccatctg tacttggtcc atcattgttg cggatgatta ctttttctac taatacatcg
     1201 ttagaataag tgatttgcaa gttccaaaaa cctgatttct gaaaaatcaa atcacgaaca
     1261 acaacatgtt ctgcatgata cagtaaacaa gcgcgtggac gtttaatagc ataatccgca
     1321 atccaacgaa gtcccttttg atcgtattca gctcttgtcc cgcttttttg atcttttccc
     1381 caatacagct cccaccaatg gtctccttga ccgtcgatta ttccttttcc ttctataaga
     1441 atatctttcg ccgagagaac attcaaaatc gctgctggcc atttcatttc tacgccggct
     1501 actcgtgtat cgatttctgg aaatgcttcg atatctgttc tccccttgag gactgcacct
     1561 tcttcaaaga taagatgact cttatctttt aaaaaaaggg ctccgactaa ataaatgcct
     1621 tttggaataa atacaggtaa gtgttctttc gcaccttgat cgattgcttt ttgcagtatt
     1681 attgtatcat cttgttgagt gtcgtttgtt ttaaagttca aagcattgat aatccctttt
     1741 tttgtccgca atacgtttct ccctatcttt cattgatttt tttcaattct tcaccaataa
     1801 atacagtttt tgaacgattc agtgggtaac ctactagcaa aatgattgcg gatacaaata
     1861 agcagaatgc tggtaacaag tttgccatcg tataaatcct ttcttgtact aaaactgatt
     1921 ggatggctcc acctgttgta gacgattggt aaccaatgag tgccagcata aatccgccta
     1981 ccgctcctgc acatgcttgt cctacttttc tcgcaaaaga atttactcca tatactgttc
     2041 catcttctct taagcctgtc ttatattgat gataatcaat cacgtcagta atgaatgccc
     2101 agaccatcaa attgaataaa ccagatccta aagtagcgat aaataaaaga atcagatata
     2161 cccatgcatt tgttatatga aggaaataca tcagcaagta catacatgaa gaagcaagta
     2221 acgcaaatac gcttgcttcc tttttaccaa ataattttgt cagctttgta gcaaatggtg
     2281 ctaaaactac tactgttccg taagtaaata aaagagcaac agacattgct tgtttattat
     2341 ggaagtaatc attgaataaa taagtcatat tcgtcccagc taaaatctga ttgatcacaa
     2401 tgaaaatgtc aacaatgact aaaataatca gtgctcgatt agctaacaaa ccttttacca
     2461 actgagaagc agatactttt tcgtttttga caactcttac tctttcagta gtcaatttac
     2521 aagttaacat atatgcgaca aatgctattg cagcacatcc gattgaaatc caaaagaaat
     2581 gattccctga aacgacttgt tgtccactct tgttatgggt atacattaaa atcggaatga
     2641 agaatcctgt agttgatccg ccaatcgcag aaccaatgct tcggaacgtg gacaacgagg
     2701 tgcggtcatt aggatttgag ctaattgctg ctgccattgc tccatacggg atattgattg
     2761 ttgagagaaa aatcccataa acaatgtatg aaacaaaaat ataagcaatc ttcaccgtca
     2821 ttggaagatg ttggacgaat ggcaaaaaca aaatgacagt cactaagcaa aatggatact
     2881 tcatttttct gatccaagga ataaatcggc cagtttctgt taactctgag acatcacata
     2941 atcttccaac catcacatca gcaaacgcat ccaaaattct cgaaatcaag aataacgtac
     3001 ctacgattgc ccctgaaacg ccaagaacat tcgtataata aatcatcaag aaactattga
     3061 ctaaacctaa aataaaacag ttacctagat caccgaacat gtagcctatc ttatcggaaa
     3121 tcccaaattc ctttttttct ttttttattg tatttgctgt aacagcattt tgtgaaagca
     3181 tttgaattcc tcctacctct tctagtaaac gttttcaaaa ttataactct ttttttcttg
     3241 tttttatatt cacaatgttg gctttttatt gcattatctt gacagataaa aaacaaaaaa
     3301 taatctaaaa acattgatgc ataagattga taactttttt tacataacaa tatatacaaa
     3361 caaaaaaatt cactaactag tgaaaataag ttagtgaacc tcatttatta aagaattaaa
     3421 ttacagatga tcttttccat catacttgaa aaactcaaaa tcagcataac ttcctctttt
     3481 tttatttaga tcatgcactg ctatcccgat aaaatttcca gtaaaccctc ctgagagtat
     3541 acacatgttt ttttgcggac ctactttctt ccattcttca gttgatacgt ctttcaaatg
     3601 aaactgtgct gtctctttct ttacagtgac tttcaaaaaa gtcttctttt ctgtgagtgg
     3661 aatcgtccaa tcttctattt gtgctactcc gttttctgat tctatcatac gtaggcattt
     3721 tcccttgtcc tcattccaag taacataaca ataaatataa ttggattcat ttaagtacag
     3781 taccagtcca gccatctgat taaaattatt aggcatgtat tcaaatgctg tctccgcatc
     3841 aaaagtaaaa tccgtttgcc gaatagctaa caaatgatgt tcgaaggtag attgaagaga
     3901 ttcaccggaa atcagacgta aaaaacctgg tctacatttt gtatcacacc aatcagcatt
     3961 tggcaaaatg cgtctggcat tccagttctt ctttagctct ccttcaaatg tatccataaa
     4021 ctgatgatct ttttcttgtt gtacctcttc atttgtctca atcattattt cttccatcgg
     4081 agttgtctgg ctatctttaa gtcttaacca atcgtcggac gtccaataca cttcttgaat
     4141 agcggtttct cttcccaaaa tagccgcacc gtttaatggt ctggtacaaa gatatgtcat
     4201 gtaccatctt cctgacgggg tttgtactaa gctcccatgt cctgtacatt gcaatgtaga
     4261 agcaggtttg tcactagctg tcagcatagg aaaaccagga tcaagctcgt aaggaccagt
     4321 aatattcttt gctcggcaaa ctgtaactga atgtcctctt cctgtaccgc cttctgccgt
     4381 catcaaataa taatacccgt tacgaaaata caaatgtggt gcctccgttt tcgctaattc
     4441 tgtacctgca aatattttat agatgggacc atcaagcttc ttcttctctg catcatattc
     4501 ttgtaatacg ataccgctgg atttattcgg tgtgtccaga cgataatccc atagttcatt
     4561 gacaagccat ttttttcccg tttcaagatc atggaacaaa gaaggatcaa agccgttact
     4621 atttaaataa attggttcgg accaaggacc tgtgatctca gatgcagtga tcaaataatt
     4681 gtggacatct ttaaacggac ggcctgcact tttgacatct gtgtaaacaa gataaaacaa
     4741 tccatcagca taactgattt gtggcgccca tatacttcca tttgtaggat ttccttgcaa
     4801 agatacttga gtggtcaaaa tatccgttgt atgtgaccag ttgactaaat ttttcgactc
     4861 atatactcgg attcctggaa gccattcaaa agaggagaca ataatgtaat accgctcttt
     4921 cactcttaat atattaggat ctggattgaa tcctcttaaa ataggatttt tcactttgat
     4981 agtctgcatg attcaggctc cttttctcat tcttactcga tataaactga atgccccagc
     5041 tgcgaaataa aaaaatgcaa aaggaaacgc aataaactga gtgccaatca acaatatgaa
     5101 tcctgttata aaatacaaac cagtggcagt tgttaagtat tttcctttag cagtcaaaaa
     5161 caatgctact gctaaaaaag caagtgaaat aaacaacaca acggcaaaca gaccagtcat
     5221 gtcctgtaat aatccaaatg tattttctaa agacaaagtt gaatgatcta cagcaagcga
     5281 ctgataactt tttttaaact ctgacgcaga catattactt aaagtaactg ctaacccgcc
     5341 aaagaaaatc aaagatagac tgccaccgac cattcctagc aatagttccc attttctttt
     5401 catttctgaa ccccctgctt ttctaaatgt atccattcag gtcttttgat cgatgtttca
     5461 taattgttat tacgttcaga gaatttgaca gtctgttcat ttttcttgtc atcccaatta
     5521 tcccaaccag ttgggtgaac atgcccacct atcttacacg cttcaaataa gacatttgca
     5581 tacggacgcc acggtcttcc taaatagacg tttctagtat caggttctgc agtcaaggta
     5641 cagctttcaa aacgataccc tgttttttga tttttcggcg tagatgctgc tgtgatgtat
     5701 ccaggatttt tactggctaa gctatggata tgacactgat gaaaaacggc atctgcccca
     5761 ccaaatatga aatccaccgt tccttcaatc cagcaatatt cataggtctg acgacaatac
     5821 tcaggattgg cagaagccgg tgtacaaaaa ggagtaccat ctttttgcaa atcaggcaac
     5881 ggacccgtgc ataaggtatc ctgataacca gatagtcgac agttttttaa agatacgcga
     5941 tctcctgaat tgaataaagc aacagcctgt cctacctttt ctcctggacc tgctgtattt
     6001 tcgatgtgaa gattttctaa tacgacattc gatccttcta agaaaaaagt agcacttcgg
     6061 aaagtcccta actggctacc gtcaagatac tcctgttttg caaaacgatt accggagata
     6121 actactgttc ctgctcccac aagtttaaaa ttggataatc tgctttctat atattcatca
     6181 tatcttcctt cttttactat caagaccttt ggatggctat ccggcaggcc tgccaaataa
     6241 tcgattcctt cttggatagt ttcaaaatcc gtcggggtat ctatagcatt ctttccaatt
     6301 atcagtttgt ctttcatcct cataaatgct cccttatgaa ttgtttccaa atatttctca
     6361 tttcttgtgt ttccatatga ccgcctgtta aagaaaaaga agaaaagttt tctggactac
     6421 ccattgattg atactttttg tccagccctt ttctcagctt cagtacgcct tcgtccaagc
     6481 acatcgtatc gttttttcca actaagctaa gacgagggcg cggagcgatt ttttcttgga
     6541 ttgctaacgt tgtataagct gtcaatagat ttggcacata gtaataaaac ccatgatgat
     6601 ctaggcggcg atgtagcaaa agtatttcga tgtccacctg tgccgctaga tcaatacaaa
     6661 ctttgacacg agaatccaat gctgtcaccc accagcttaa taagcctccc atagaaagac
     6721 caatcgttgc gagccgttga gtatctgtgt cttcccttgt ctccaaataa tcgatcaagc
     6781 tgatcacatc ataaatacgc attccccata acgtttttcc tgttaataaa aattgtttga
     6841 acaactcgct ttcagaaata cctccgcgtt cttcaaatcc ccaagcatca atcgaccaaa
     6901 cagcatatcc cattcctgtc agtacttctg caaaagatgg agaagctaag taaggagcac
     6961 catggatcaa ttcacttttc ccgactgaaa aatctccgcc gtgagaatgc aggtaaagga
     7021 ccggcggaaa cggtccttct ttttctggat aagcatagag ggctggtact gtttccaatt
     7081 catttaagta caattgatag tattcaagca taaaaccgtt ttgtttttct cggtataatc
     7141 gttttccact aggggtatgt ctgctagatg gagcacctaa aaaatcattc aactgcataa
     7201 gcaaagtttt tacgaacaac cagttcatcc atattttctg attgatttga ttggaatttc
     7261 tcaatactga tttctttagt attttctaat agaaatgctg gtccctcgtg attttcaatc
     7321 gacatctggt taaaggaaac cttacccgca aagccaatat aaaatccttg tctgctcatt
     7381 tcctctattc ctgtcatcat agcaggaaca ccgggaactg catcttgggc catcgagaca
     7441 tcgatattgt caaatgtgat ttcttgtatg aattgttccg ctaatccata aataaaacct
     7501 gcagaagcat ggacattcct tgccgtgata ttcgaaaaat ggatccttct gaatgctggt
     7561 gtccgttcat ctatcggata agcctttttt tcccatacat acggttcttt ccctcgcgga
     7621 ccacagaaat aataaagatt cagtataaat ggacacatca cattatccat gactatattg
     7681 gatactcgaa tatcttcaac gatcccgcct cgacctcgtc tagatttcaa tcgtattcct
     7741 cgatcagttt cttggaagat acaatttgaa atggtaatat tacgaatact accactcatt
     7801 tcacttccta atacgacacc gccatgtcca tggaccatcg tgcaatttgt gatcgtgata
     7861 ttttcgcaag cgatcctttc gtacgtatct tcagtccctg ccttgattgc aatacagtca
     7921 tctcccacgt caatatggca attactaata cgcacatttt tgcatgattc tggatcaatt
     7981 ccgtctgtat ttggtgaatc cgctgggttc aagatcgtca agttatcaaa cgttgcatta
     8041 ctgcaaagaa tcgggttgat cgtccaactt ggtgactgga tcaatttaat atctttcaca
     8101 gtaattcgat gacagttatg gaaactcatc aatttaggac gaggataagc gagattatct
     8161 ggttcatttc taaaagtatg ccaccatttt tttccatttc catctaatgt accgaaacca
     8221 gtgacagaga tgttctctac attttgagca tagatacagg aagcataaac ttttcgatgg
     8281 actccttccc aacgtgaatg aacaacagga taatcttttg gatcgtcaga gaatttcaga
     8341 accgctcctg cgcttaaatg aagttcgaca ttgcttttta aaaataaagc tcctgttaga
     8401 aattcacctg ctggaacaac tacggtcccg cctccgtcac ttgctgcagc atcaatggct
     8461 tgttgtattg cttcagtatt caattcatca attgatgcgc caaatgtcaa aatatcatac
     8521 atatttataa tgcctccact tcaatcaatg cttgcaagaa tgcaccaacg cctttttgat
     8581 cattacaaat aattggttca ctgatgtagt aagcatatga accatctcgc tgatctgctc
     8641 cgcctaaccc tgctacttga cagtttttat tcaagttcag ccagccttct tttgtttcca
     8701 gaacaaattc atcaagtaat ccttgatgtg atttcttcac ttgtggaagc cattcttctt
     8761 tgttcagcag tcccaaacgt attcctttag ccattgcgta aacaaacata ctactgccgg
     8821 aagcttccag ataatttcct ttccgttttg tttctgttgt tacttgatac catgtcccgc
     8881 tgttttcttc ttgatatgga agtaatgcag ccagtgtctt ttctagaatt tctttcagca
     8941 aagaacaatc tgtttcttca tgaagtaatt cataggtatc tgctgcagcc atcaaatacc
     9001 agccaatcga tcggctccaa aaatgatggg atagacctgt ttttggatca gcccatggtt
     9061 ggaccttctt ttcatcccat gcatgaatca gcaaatttgt ttttggatcg aatagatgtt
     9121 tataactgat ttcaaactgt ctcaaaacat cttggtaatc tttttcttca ctaaaattct
     9181 ggataaattc agcataaaaa ggagaaccca tatataagcc atccaaccaa atttgataag
     9241 gataaatttc tttatgccaa aaagctcctt cggatgtgcg tggatggttt gccaactgct
     9301 gggaaaggag ttctgctgct tttttatatt tttcttcgcc tgtttctttg tacaataaaa
     9361 agaaaagctt tcctgtattt acatggtcga tattgtattc ttcaacgctg tagccacgga
     9421 tcgttccatc ttcttgcacg aaatagtcga tattgtcttt tatgaaatca aaataaattt
     9481 tttcttgggt tcgttcccaa agtaattgga accctttaag tacgacgcca tagtcataag
     9541 accattttcc tttataccac ttttcttcat ataagcgagg tgttctttcc atgatacttt
     9601 ttgctaattt ctttgaccag ttttccatta tttgctctcc tttaaaaatt aaaataggat
     9661 ttgggacaaa taccaagaag tatttgtccc aatcgtctat attactgtgc cgctgctttg
     9721 tatgcttcct cgtactcttg tgtgattcga tcgcctcctt gtgctttcca gtcttctaca
     9781 gcttttttga atccatcttc gtcaagctgt cccatgatgt attgcaccgt agcatcaatg
     9841 acgatttttt caatttctga tcctacttca ttgttcgtcg gtgaatccaa tggcacagaa
     9901 ggatccatta cagcaaattc ttcattttct ttgatcaatt gattagagaa ttctttttca
     9961 gggtctgtat ctttgaaaga gaacgtcact tcactaggac gagagcttga taacggttgc
    10021 acctcttgtt gccaaagatc catatcgata aattcgatag aaccatcatc attcaattca
    10081 taatgcgttc cttcgatacc gccagtcatc aatttataca catcttcttc taaaagatca
    10141 tcaacaaatt gaagtaattt cttcaattgt gcttcgtctt ttacttgaga tttgggaaat
    10201 gctagcaagc cgccaatacc atttccttct gaccaaacat gataaccgcc gccttcacca
    10261 tctgagatct tgtttacagg cactaattcc atatcatctt gaataccttg acccatcgtc
    10321 ttcagattct tgatatccac cattccagtg tagattccag ttcttccttg tgcaaattgt
    10381 tcttgctgat cagtcttttg ggtaactgca aagtcttgtg ccaaatagcc attctcaaat
    10441 agatctcttg aaaaattcaa agctttcata tactcttctg tatcaaattc tggagtgaat
    10501 ttgccattat cgtctacagc ccagccattt ggtgctccaa aataagaagt gaaaagttta
    10561 aagctggtat aacgaatatc actaggcgca cgatcgccaa aaccaactgt gtcgtccaca
    10621 ccatttccat caggatcgtt ttctgtaaat tgtttagcta cttcataaag ctcatccatg
    10681 gtagttggaa catctagtcc tagattatcc aaccagtctt ttcgaatgac taagccagca
    10741 cgagcgtagt ctttttgtat cggtacgccg tacaaggcac cgtcgatact cgcagcttcg
    10801 attctatctt cagaaatttg acttaaattt ttatagtctt ttaaatattc tgatacatcc
    10861 cagaatacgc ctgattttaa cgcattgcgg acagaagagt ttttcaacat cgcaatttga
    10921 agtgtaacga tatctcctag ttcatcagaa gccaatgcag ttgttaatct ttcttctttt
    10981 gaagcatcag gaatccagtt gaatgtcagt tccgtatcgg ttttttcttc gatcaagttc
    11041 acaatcgtgt ctgtaggcgg tgaagcatga tgcaaaatat ttaaccaagt gattttagct
    11101 tttccatctt ctgtctctga agaactgtta cttgaactgc tgccgcatgc ggcaagtgct
    11161 agaattcctg caaaactaag acctaatttt acgagcgttg cttttttcat aaattttctc
    11221 cttcactgtt ttaataatat ttttgttttc ttctgttttt tctgtatatg agttcttcca
    11281 ttccaaatgg caaaatatag aatttgctgt ccacgtgact gcggaaaaga agagactgcc
    11341 accgataaag gttaaaacac ctggcattgt ttggatgatc atcagataaa tccctaccat
    11401 acttaatatc aacactaatg agtaatgaag atgtgagaat ccgaataaaa atgccatttt
    11461 cattttgaaa aaatatcctt tccaatcata atgagccatg attgggaaaa tatagagtgc
    11521 tgagagcaca tatatgaacg cagcaatata caaagcgatc ctaagatacc aattgtgtat
    11581 gaaagaaaga tccacaagta aaacaatccc gatggcgcca tatatccagc tcatcagcaa
    11641 ggtttcacga tagttttctt taaaatatgt gaagtacgtt ttcgtcaaag gaaacgtttc
    11701 ttttgagcgc agccattttc taatcactgc aaccatcgca tacgatgcag gaccgaaagt
    11761 aaaaactccc aaacctgcga tgactaaacc gccccacaga aaattcaaat aaaccaactg
    11821 taaaatacga tttagccttc cgtttatttt atctaatgac tgcagcatat ctttccctct
    11881 ctttctatct tagtaaacgc cgtcttctcc tagctttttg gcaatcttat tagctaaaat
    11941 taccataaac aatcctacga cccctttaaa caatcccatt gctgtactga aacttaactg
    12001 tccattcttc aatccagctg tataaatata ggtgtcgaaa atttctgcaa cgcttcgatt
    12061 caatgaattc aataacaagt acatatgctc gaaccctaag tctaatgtct gaccgatttt
    12121 tagaatcagc aaggtaatga ttactggacg aattgccggc aatgtaacat gccatgtttt
    12181 gcgtaagcgt cctgctccat ccatttctgc agcttcatac aactgtgtat cgactgcagt
    12241 tatcgctgaa aggtagatga tcgtagacca gcccaactct ttccagatca cttgtccgat
    12301 atatactgtg cgtgtccatt caggggatgt tagaaaactg attttttcaa atcccattgt
    12361 tgcaaggaat tcattcaata cccctccgtc aacattcaaa aatacataag taatcgaaac
    12421 aatgattacc caagacatga agtgagggat gtaaatgatc gtttgaatcc cgtttttcaa
    12481 tcgtttgttc gttacttcat ttaatagtaa agacaaaatg attggcatcg gaaaaaacac
    12541 gaagatattt aatccgaaca agatcaacgt atttcttaat aatgtaaaga atgtcggttc
    12601 tgtaaacaaa cgaatgaaat gtttgaaacc gacccaagga cttcccatta ttcctaaaaa
    12661 tggttgataa tcttgaaaag caataacgag tccccccata ggaagatacc taaaaatcaa
    12721 gaaataaagg actcccggca gaatcatcac atataaaaat ttattcgttt tgattcctgc
    12781 aattattttt tttcgtcttc tgagcttttc ttcttttttc gatagcgtca gttgaaatgg
    12841 ttcttgtttc tttacacttt ccataagccc ctccttagtt ttgtgaatgt ttgctgctta
    12901 tgacttcatg atagataact atctgaatta cgtatataat catttttacc gtaagtaaaa
    12961 acgcttacat agcaatgatt tttgtgctat acaaaacgat aaagtgtatt ttttcacaaa
    13021 taaactacgc atagcaaacc ttctattttt ttctatctga cacttagcat aggaaatgat
    13081 tatatacgta atctttcacc gatgataaat tgaacatata gaaacagaaa catttaattt
    13141 attttgagga ggagcctatc tatatgaaaa agaaagtctc tataggagaa agaagtttta
    13201 cacttttcaa caatacgttt ctaattttgc tagctttgat ctgtatcgtt ccttttttaa
    13261 atatcatcgc tacatctttt gcttctacac aagaagtcgt cgcgaaaaag tttatccttt
    13321 ttcctactac cttttcttta gacgcgtatc gctacattct ttctacgccg accattttta
    13381 gagcacttgc tgtttcgatt ggtgttacag gtgtcggaac gatcgtcagt atgtgtgcaa
    13441 cttcactgat ggcctacggt ctttccagaa agtatttgtt tggtcgaggt ttcgtcaact
    13501 ttcttgttgt attttctatg ttgttcagcg gggggatgat tccaacgttc ttagttgttc
    13561 gttctctagg gctggtcaat tcttactggg ccatgatcct gcctgtggct gttaatgcaa
    13621 tgaatatgat cattatgaga aactttttcc aagccttgcc ggatagtttg gaagaatcag
    13681 caaaaatgga tggttgcaca gattttggtg tatttttcaa aattatgctg ccattagcgt
    13741 taccgtctat tgctactatc tcgctttttt atgctgttac ttactggaac acttatatga
    13801 ctgctatttt gtatatcaac gattcatcta aatggccgat acagattctt ttacgccaaa
    13861 tcgtcattgt atcaagtggg atgcaagcag aaagtagtgc cgttgatgtg attccaccag
    13921 cacaaacagt taaaatggct gttatcgtta ttgcaacagt gcctatgctg attgtttatc
    13981 cttttgttca gaaatatttt gtcaaaggag cactcgtagg ttctgtcaaa gggtgattat
    14041 gtactgaacg caaaatggta gttgtgtcag aagtggtcag cttcaagaaa taagaaggca
    14101 tttacgaaaa ttgcttctta aatttttgtg aaatttcggc ttatttttcg aagaatctac
    14161 tcctggaaca ccgtgtatca gaggttgtga aagagacgtt cagccttgag cgatgataaa
    14221 aactctcaca aacattgcga cgagtaaccc acaggagcaa taagaagcga ttttgaaaaa
    14281 tagcttccca tatttcacaa aattatgcct tattgtcgat agcctgtctc ttgaacgcca
    14341 tttattcgta aaaaagaact gtgacaagac ttttgtcaca gttctttttg cgtgcttagc
    14401 cttgaaattt aactatccat aaatacaaat actagggtta ttctaacttc ttttattgct
    14461 tgaatcagtc cacaagaaaa acagcctctt gattcacaaa tatttttttc gatattctcc
    14521 cggcgtaatc gattccttct ttttaaagaa acgaataaaa ttttgcggat ttcgatattg
    14581 caatctttct gcaatctctt ttacggagag gttagtctct ttcaaccatt tttttgctac
    14641 ctctaaacga tgattttgaa caaaatcacc aaatttttct cctgtttcct ttttaaatac
    14701 attacttaaa tagttagggt tataatgcaa cctatcagcg atcacatcta aagacagatc
    14761 acgatcatat tctgtgtaga cgatatgcat aatattctcc gacaaatttt taaattcatg
    14821 atcagtgatt gcttgagagc attctgtgat tggcagaact aattgttcta aaacaagttt
    14881 ttctagttct ttgggatgat aattgttcag tgcttttaca taaatttgtt tcatgttatc
    14941 aaagtttttt gaatctactc ccaataactg tcctaattga acgagttcat tgatcaagcg
    15001 gaccgaaact acttcccgac tcaaaggatt tttattttgt gcaaacaatg catcaatcaa
    15061 ttcatgtact aaattcttca cttcctgatt tccagaacga atggcttcaa acaatcgatt
    15121 ttgttcttct atcggatatc taataagtgt tttttcatga gcagcaggaa cgatttcctg
    15181 ataaaaaata attgaacttg gaccagtatt tacacgataa tacagggctt cttttgcccg
    15241 atcaaccgat tgcttgcttt cattcagcgt ttcgaaccgg ttactgatgc ctatactgat
    15301 agttaaattc aagtattctt ttacacgttt ttgaatgagt cggcaatact ccatgacttt
    15361 tttgcttgct tctgcatcat ctttatccat tcgataaata gtggcttgca tttcttcatt
    15421 caaaacgatc ggcagcattc gattttcctt tggcacaatt tccgtgatca tgttgttgat
    15481 cgctaaaagt agcaaatcac gctccccacc gtgactatct tctaacagat cgatttgaac
    15541 caaagctgta taatagcagt cattttgaga actataacca aattgctgca accgctgatc
    15601 tagttctcgc ctttctactc gatttctaaa taaactaagt acaaatagcg tttccagctg
    15661 tggcttttgg gtaactaagt gtgcacttaa cgcttctttt tctcctatga tccgactgac
    15721 tgattgagcg accaaatcta gttctttccc actgaatcct tttgatttaa gattcagacg
    15781 ttcctgtatt tgagaaatcg gacgggcaaa tctgtccgaa aataagtagg aaagaagacc
    15841 aatgagtcct accagtgtta aagacactgc aactagcccg attctcagat tgcggatcat
    15901 tgcgccaatt gcactagagt caacttctaa tctgtaaatc caattattat aatctgattt
    15961 cagtactata tacgttttat ctttttctct tatcactttc agctgattgt aatctagatc
    16021 cacgtccgtt aatacagttg gttgctcttt attttttact gtctgagtag taaaaaggtt
    16081 gccaacttcg ttttcaatag aaagtatgtc ttctccactt tcaccaacaa cttgttctat
    16141 tgtatgtttc tctatcgtag caattcccaa tgcatatttt tctttttcaa acattggcaa
    16201 agaaatcacc atttcgattc ctttgttttt cttttgccaa aataaattat ttttgttatt
    16261 tatgtacttc tgttgatact tttcaacttc ctcttcggtc agttgactca acgatccatt
    16321 gattactccc catttaccag ccaaactgac taaatcataa ttattatcat ccataacaat
    16381 cgtttctata aaatttagtt ctttcctgat ttcagaataa gtggagtaat ctgtatatgt
    16441 cagcggatgc ttgaatatgt ccgagaaatt tttggtcgaa ccatacgtag aaaacgaata
    16501 ttcaatcgtt ctaattttcc attcaacgtt agttttaact tgcctgagca aattcttttt
    16561 gtctgttaaa taactcgatt cgatcgattc ataggtattc tggtaaatga ataaactaaa
    16621 tcctatgaca agtacggctc ctaataaaaa catcggtaaa aatattttat aaaatactgt
    16681 acttttcttc attttcttcc tctcctcctt ttaaaataaa aggctttcat ttttctgtaa
    16741 aattgatact catctaatta aatgagcatt ccccgctttc aagaatagca taattaaaaa
    16801 taaaaatcca agtaattttt aacgtgtgca atcttttcat atcaaagatc tattgactta
    16861 tcgtagttat cgtaatatga tgaatgcgtt aacaaaaagt gaaaaagtaa ggaaaatgat
    16921 ggaatggtaa cgatcaaaga tatcgctaaa gcagctggcg tttctcatac gacagtttct
    16981 cgtgctttga ataacagcag tttaataaaa aatgaaacaa aacaaaaaat acgacaacta
    17041 gctaaggaaa tgaattattc gccaaactat agtgcaaaag gtttagtgaa tcaaaaaaaa
    17101 tatctaatcg gactattttt ctcaagtttg cataaaggaa cttcatcaaa tttcctagca
    17161 gattccattg caggcatcca ttcagtatta gacacaaatt acagtttatc tgttgaaagt
    17221 atcgatgttg ttgatttaac agaaatcaac ctgcaacgct acgatggact gatcgttatg
    17281 agtcaaagtg atgatgatca gcctttcatc gactatctca aagaaaaaga atttcctttc
    17341 gttgttgtca atcgtcacat caatgatcca gcggttatca acgtcactgc cgatgatgcg
    17401 gccggtgtta tgcaggcagt agattacggt attggatgcg gacatacgaa gatcgcttat
    17461 attggcggaa agaaaaattt tcgttcgaca aaagaacggg aaaaaggggt attgaaaagt
    17521 ctaaaaaaag cgagcatccc tgtcaatcca gcctattttt taacaggaga ttacagctta
    17581 gaaagcggcc tccaaaacat ggaataccta ttatcacttt ctgacctgcc tactctggtt
    17641 ttttgcggca acgacgacat agcgattggt gcattgagag ctgtacattt agctggcctc
    17701 cgtgttcccc agaacatttc tctgatcggg ttcgatgatt ctccagtcgt ctcctatctc
    17761 aatccgccgc ttaccaccgt acgtaagcct ttgaaagaaa tgtgtcaaga aggaacaaag
    17821 cttttactag atttgatcga aggcaggacg atcgaacaat ctaaaattga gctctccacc
    17881 ttgttgatcc ttcgtgagtc gatcaattac ttgtaaacta caagtaattt tatataaaaa
    17941 tgttaacgtg tgcataacac agaaaggaag tttatatgaa aaaactgaca aaagaattag
    18001 tgaaaaaaaa cgaagcacct gtaaaagttc ttcagtttgg tgaaggcaat tttatgcgtg
    18061 gatttattga ttggcagatt cagcagctga ataaccaaca attgtttaaa ggtaatgttg
    18121 caatcattca acctttagaa caaggtcttg gaaatatgat gaaccagcaa gataatttat
    18181 atacggtcat tttacaagga ctcagcaatg gcgaaatcgt tgatacttcc gagattatca
    18241 ccgtagtaga acaaatgatc aatccttatg atgaatggga tgcttatcta tctctagcag
    18301 aaaatgacga cttggcctat atcgtctcca atacaacaga ggcaggaatc caattcgtgg
    18361 agactgataa tttaacagat actcccccac agagcttccc gggcaaactg acagcctttt
    18421 tataccgacg tttcaaatta aacaaagctg gctttaccat cattccttgc gaactgattg
    18481 acagaaacgg cgaacgtcta aaagaaatca ttttacgcta cgcagaaaaa tgggatttag
    18541 aacctgcttt tgttgagtgg ttagaaaaag aaaatgtttt ctgttgtagt ttagttgatc
    18601 gcatcgtccc aggttatcct cgcgaagatg caggtgtttt caatcaacgg cataactatg
    18661 aagatcaatt gatggtcaaa gcagaaccat tcatgctttg ggtgatcgaa gggcctaaag
    18721 aattggagaa tcaactacca ttcaaacagg ctggcttgaa tgtcatcatc acagatgata
    18781 tgactcctta tcgtgaacgt aaggtgcatt tgcttaatgg accgcataca gcgatggtcc
    18841 ctcttgcttt gttggcggaa ttggaaactg tagaagaagt aatgaaagat cctttattct
    18901 ccgcatatgt tgatcagtta ttcaatctag aattgattcc tatgctttct ttacctaaag
    18961 atgaattagc catttatgct gaccaaatca aagaacgttt cttgaatcct tttgcccatc
    19021 acaaattaga agcgatttca ttaaatagtg tttcaaagtt cagcacccgt ctgcttccag
    19081 tgttcaagaa gtatatcgaa gaacaaaatc aggtaccacc gttaatcact gtttcactag
    19141 ctgcgctact tcttatgtat cgaggcgatc aagtaaagcc acatgatgat gaaaagacga
    19201 taagcgaatt tactgatgct tggtctgata atggaacagc tattcctcga ttattgcaaa
    19261 acgctgcgct ttggggagaa gatttgtctc aaataccgaa tgtgacagat acagttcaag
    19321 aaatagctgc aaagatcgat caaaaaggtg tccggtcagt attacaagaa atgaaaggaa
    19381 cgatggtcca tgcttgaaac cctgcaacca acaatgaaat taaatcgacg agacagtgtg
    19441 gtcgtcgcat taacccctat tccaaaacaa acacaactga cgattgatca gcaaacgatc
    19501 accactcttg aagatatccc gcaaggtcat aagattgcat tgggtgattt gaaagctgga
    19561 gacaacgtga tcaaatatgg ctatccaatc ggtcatgtga cgacagacgt aactgccggt
    19621 caatggctgc acactcataa tgtaaaaacc aatctttctg gtgaattgga ttatcgatat
    19681 gaaaaagatg tccatccaag tcattacctt tttgagaacc gaacatttca aggttacttg
    19741 cgaaaaaatg gaaaagtagg gattcgtaat gatttgtttt tagtacctac cgttgggtgt
    19801 gtgaatggca ttgctgaact gatcgtcaaa cagttcaagg aaaaacatcc agatctggga
    19861 cagtttgacc atattacgat tttaaagcat ccttatggct gttcgcagct tggaaaagat
    19921 catcaaaata ctcgagaaat tttagcggac gcagtaaatc atcccaatgc cggaggagtt
    19981 ttagtatttg gattaggttg tgagaacaat acagttcctg aattcaaaaa aattttaggt
    20041 gaatatgatg aagaacgagt gaaatttcta gtggctcaag atgtttacga tgagatcgaa
    20101 caaggtgtgg ctctattaga agagctttta acagcggcgg aaaatgacca gcgcatatca
    20161 gtcccgctct ctaagttgaa tgtcggtttg aaatgcggcg gttctgatgg tctatcggga
    20221 ataactgcta atcctttact tggtgcattt tctgactact tgattgctca aggaggcagc
    20281 acgatcttaa cagaagtgcc agaaatgttt ggcgcagaac aagtattgat ggcacgagcg
    20341 gaaaatgaag aagtttttga ctcaatcgtt gacttgatca atgacttcaa acagtatttc
    20401 ttgtcttacg gggaaccagt ttacgaaaac ccatctcctg gtaataaagc aggtgggatc
    20461 actacattag aagataagtc tttaggctgc acgcaaaaat caggaagctc tcctgtcgtt
    20521 gatgtgctac aatatggcga aaaaatcaga aaaccagggc ttagtttatt gcaagctccc
    20581 gggaatgatc ttgtagctgc ctctgctctt gcttcatccg attgccagtt ggtcttgttt
    20641 accacaggaa gagggactcc gtttggctca tatgtcccaa cggtcaaggt atctacgaat
    20701 acaactcttt ttgaacgcaa aggtcattgg atggatttta atgcaggcgt cttattagaa
    20761 caaccaatgg aagtaatctt agaatcgttt gttcaaaaaa tcatcgctgt agctagtgga
    20821 gaagaaacga aaaatgaaca aaatgacgtt cgagaaattg ccatttttaa aaacggagta
    20881 acactttgat tttcataaaa cagtataaaa agaaagaagg aagatttatg tttttatctg
    20941 atgatttttt attaaaagac gattgggcga aaaagcttta ccattcctac gcaaaaaaca
    21001 tgcccattat tgattatcac tgtcacttag atccaaaaga aatttacgaa aacaacaatt
    21061 tcagcaatct gacagaagct tggttaggag gcgatcatta caaatggcgc ttgatgcgag
    21121 cttgcggcgt gcctgaagaa aaaatcacag gaaatgcttc tgattttgaa aaatttttag
    21181 cttggtgtca aaccgtacca aaaattatcg gaaatccgct ttacagttgg tcacatcttg
    21241 aattgaagcg tttcttcggt attgacttgt tgataaatga agaaaatgca gagaaaattt
    21301 ggacacaagc aaatgaaatt ttggcagctc ctgattttcg ccgtcgggaa atcgcaaaaa
    21361 aatcgaatgt agaagtgatt tgtacaacag atgatcccgc agacgacttg cactatcatc
    21421 agttgcttgc tcatgaagaa ccagatttga aggttctacc ttcattccgt ccagataaag
    21481 cactcaatat tgaaaaagaa ggatttaatg catgggtcac actactggaa gaagcagctg
    21541 accaaacgat caccacctat caagaactga tagaagtctt agggcagcgg atagaatact
    21601 tccatcaaca tggatgtcgt gtttccgacc acgctttaga catcttacgc tataaagaag
    21661 cggatgaaac agtattagaa gagatttttc aaaaagcacg agctaacaaa ctattatctt
    21721 cagatgaaat cgatgcttat cgtacagaaa cactgataca tttgacccac ttctatcatt
    21781 ctcataattg gacgatgcag ctgcacatcc atgcttatcg taactgtaat acacaaatgt
    21841 tggaaaaatt agggcccgat accggctatg atggaatgaa tgatctttct ttgactattc
    21901 ctctgcaaaa attattgaac cgtgcagaag aaacggatca gttgccaaag acgatccttt
    21961 attcattgaa tccgaatgac tatcctgcga ttttagcttt gatgggctgt ttccaaaaag
    22021 aacagaatgg aaaactgcag ttaggttctg gatggtggta caacgatact cgagctggta
    22081 tgcgcgatca attgacacaa tttgctgatg gtagtgcttt ggggaatttt gtcggcatgc
    22141 tgacagattc aagaagtttc ctgtcctaca ctagacatga atatttccgt cgtgttcttt
    22201 gtgaattttt aggcgaaatg gtcatgcgag gagaagcacc tgaagatgaa caacttttag
    22261 gaagtctagt tcaagcgatt agttatacaa atgctaaaaa ttactttggc ttttttgcct
    22321 aattgattaa tagtaacagt aacgaatcaa aaacaggata gtgaaataac ggaatccgtt
    22381 tatccacgtt ttagagaaga agacggacca aatttgctcc gtcttcttct cttgctgttc
    22441 tgcttcattg cctataaacc tttatgaaag aagagataac atgcctacta tccatattgc
    22501 cggtgattct actgcggcag aaaaagatga aaacaagcgt cccgagacag gttggggaga
    22561 aaaaatctct gcttattttt cacccgagat ccagatcaat aaccaagcaa agaatggacg
    22621 cagcaccaaa tcatttatcc aggaaggaag gttagcccgt ctagcttcac agtttcagcc
    22681 gaatgatttc ttatttgtac aatttggaca taacgaccag aaaatccaag aagaaagagg
    22741 tacgcttccc ttcggtagct atttaaaaaa tctgcagata ttttttgaat gcgcaaaaaa
    22801 agcgaacgtc caaatggtct tactgacatc tgtgacgcga cgagattact tagaaaacgg
    22861 aacattgaat ccagatatac ttggagacta tccaaaagcg atgcgtgcat ttgctgagaa
    22921 acaccatatt cctcttttag atgtgttctc aagatcacaa gaattgttcc agaccttctc
    22981 aaaagaagag acaaaaaaat tctacctgca tcttatacct gatacttgta aaaattaccc
    23041 agaaggacta aaagacaata cccactttag tccagaaggc gctgataaag ttgcccgaat
    23101 aattgttgaa ttgataaaag aatcccgtct gcctcttgct aattatttac aaaaaggagt
    23161 ttgagatgtt tccattaaat ttaggcatcc gtgcccacga tttagatgtt cgaaatcgtg
    23221 aagaaatcgt tcaaaaagta tcacagcttc acttgtccca tatccaattt gcaccacaaa
    23281 aagcatttcc tgaacaactt aaattaactg acatgacact tgggagtgct gcctattttg
    23341 gtgaatactt ccaaaaaaac aatatcgaac tttccatttt aggatgctat atcaacctat
    23401 ccagcaaaaa tcaagaagtt cgtgcacaag cattggcaac tttcaaacag caaattgctc
    23461 tgtgctctgc ctatcaagcc aagatgattg ctacggaaac cggtagtgtc tctgtcggtt
    23521 acacaaaaga aaattttact gaagaagctt atcagatcgc cagaaattct atcattgaat
    23581 tagtcgctca tgcagaaaat tttggcgtaa ctgttgctgt tgaagcaggg atcaatcatc
    23641 caatctataa ctatcagtta gctaaacgtt taatcgatga agtagcttca ccaaatttaa
    23701 aaatcatttt agattgtgcg aatttgatgc ataaagaaaa tcatgctgat caggaaaaag
    23761 tgatccgagg tgccttggac aatttacatg gttatattac agcgcttcat ctcaaagact
    23821 atatcatgga aaatggaaag atccgcatgg tacctgttgg caagggctgt ttagatttcc
    23881 gcccggtact gcattatatc aaatatgagc gtcctctaat gtacgccact cttgaagcta
    23941 ctcctgagat ttatgttcct gaagcaatag aacacttgca gtttatttac caagattgtt
    24001 aaggagaaga ttatggagga acgaatacag aaaagttatc aaaaatatca tgcaaatgct
    24061 tttcagacat tgctgcatct ttatcaggga aattattggc gttttgccat gtcaggactc
    24121 ttttttatta tcaaacatct tccatcttgg ttaatgccga tcgctattgc caatgtaatc
    24181 aatgcagctt catcgaaaga ttcttctcag ttgcaggcca tttatttcaa cgcttttttg
    24241 atggcttgtc tgattggtca aaatatattg acgaattatt ttcatgtaaa ataccatagc
    24301 acttcgatcc gtcaagtaga agctggacta agagcgaccc ttatcaagaa aatccaagaa
    24361 ctatctattc cttatcaaaa agaattgcaa tctggacgaa tccagtcaaa gatcatccgt
    24421 gatgtagaag ctatccaaac gttgtcctct caagtatttg tcagcggatt aaatatcgct
    24481 gtcaatttat tcgtagcttt aggtatcacg ctttataaaa gtcctgttgt tttcatgttt
    24541 ttcttattga ctgttcctct cgccgcattc gttactctct ttttccgtaa aaggatcaga
    24601 cagtccaact cagacttcag gcaagaaatg gaagagactt ctgcaaaagt gatcgaagtg
    24661 atcgaattag caccgattgc tcgagctcat gggttagaaa aacacgaaac aactcgctta
    24721 aataagcatt ttactcaaat ctatgaaaaa ggattccact tagatatcct gcaatctgtt
    24781 ttcggatcag tcagctgggc tagttttcag atatttcagc tgatttgttt gattttcact
    24841 gggatattag ctttacaagg gcgcatccaa cccggcgatg tcgtgatgta tcagacgtat
    24901 ttcacgacga tcgtcaattc cgtttctgga atgatcacgc tgattcctac gatttcaaaa
    24961 ggcatggaat ctatcacttc tattggcgaa ctgttgattg ctggcgatgt agaaacttat
    25021 cacggtaaga aaaaaatcca acatttggat ggaaattttc gttttgagga tgtttctttt
    25081 ctttatccgg actcactcaa accgattatc gatcattttt ctctagaggt gaaagctgga
    25141 gaaacaattg cttttgttgg gccatctggc tctggaaaat ctacactcct taacttattg
    25201 attggattta tccagccgac ttcaggaaaa atttttctag atgatcagcc tttggatgaa
    25261 ctggatatgc gaagtgtgcg aaattattta gccgttgttc ctcaaaccac tttgttgttc
    25321 tccgcttcga tcaaagagaa catcacttat ggcttgaaaa acgtatcaaa agaacgttta
    25381 gatgaagtca tcgaagctgc gcaactttct tcactgattg accagcttcc tgatggtctg
    25441 gataccttag taggcgaaca tggcaacaag ctgtctggtg gccaaaagca acgtatctcc
    25501 attgcacgag cgttgatacg tcagccaaaa atcattttgc tagatgaagc aacctcagct
    25561 ttagataacc agtcagagaa aaaaatccag caagccctga attacctgac agaaacaccc
    25621 actactttta ttgtggctca tcggctttca acgatcaaag aggcagataa aatcgttgtg
    25681 atcgatgaag gaaaaatcgt tgaaataggt acttacgaaa aactgttagc tcaaaaaggc
    25741 tatttctacc gcttgaaaaa tgaatgacaa aaaataggag ctatgacaag acttttgtcg
    25801 tagctcctat ttctgaataa acggtgttct cctgccaact cctcggtcac aagtcacaat
    25861 agtcatcaaa catgagaagc tgttttttga aattgttcct tgtaactcag agttaaacgg
    25921 taggctcacg acctcttggt aaatggtgtt caagagacag cctatcggca ataagaagca
    25981 attttgtcat cgctcaaggc cgaacgtctc tttcacaccc tctgttgttt cataaaatag
    26041 ttttattcgc tgtaaaggtc gcgaactggt gtcatgatga tacggttcaa gtcattgatg
    26101 attgtactga agccttgctc tttttgcatc aagtcattga ttacttcttc tgattggatt
    26161 ttcacagcca tttcttgtgc tttcattgca tcttcgtcgc tgaactcttg tccactcatt
    26221 tgtttttctt gtaattcgat ttgcatcgct tggaagtctt tgaacagttt gtgtgcttct
    26281 tcgtttgctt gtactttctc gtacgcttct ttcaacgctt tgaattctgg taattcacgg
    26341 atctcacgtt cgatttgatt cgcgctatcg tagatgtttg acatgttatg ccctcttttc
    26401 ttttagtagt tactctctat tgtaacatgg ggttattcgt tttcaaaggg gctactctcc
    26461 ttgatatttc cgccagaggt ctttagccgc ttcaccaatt ccctgaacgc cttctttcac
    26521 catatcgccg aagtttttca gcccttcttt tgcttgttca ccatattgat tcaagttatc
    26581 ttgccaattt ccagactctc cattagaatt tcctgtgttt ccaacttgat ctgcagctac
    26641 cacttgtcct cctgtggcat aggcatctgc tacactaaat cctgtttttg aagtatacgg
    26701 aaggatgcct tctgccgctg atttgaagac tttcccgaca acatttccac ttgtcccttc
    26761 caaatagtgc agcttgctgg attcttcgta acccatccat gtcgaaatca ctacgtctgg
    26821 cgtgtaaccg atcatccatt ggtcatttgc ttttgtggca tcgaaattag tttctgtggt
    26881 tcctgttttc cctgctatcg tataacctgc aggattcgca gcagccgctg ttccatttga
    26941 aaatgtacca agaagcatgc tggtcatttc atcggctgtt tcctttgata tgacctgttt
    27001 tggttttttg tttgtgttat cgacgatcac cgctccagtc gaatcaacga ttttcgtgat
    27061 aagatgcggc gtatacatct gaccatcatt ggcaaatgca ctgtaagcac ccgccatgat
    27121 caatggagat actccttttt ccagtccacc aagggctaag ccataatact tatcagattt
    27181 tgctaaaggc aggccgaatt cttctgcttt atcatatcct ttttgtaaac cgatctcatg
    27241 caaaagccat acagtaggca aattcaaact ttgtgcaaca gcttgataca tcggtacttc
    27301 tccttggtat gtcccgtcaa aattatgcgc atcgtaataa ctttgcggtt cgtctttcaa
    27361 gatactggaa ggcttgtatc cagcttccag tgctggtgta tatacgctta atggtttgat
    27421 cgttgatcct ggtgaacgac gcatctgtgt agcaaagctg aatcctctaa agacatgatc
    27481 tcctcttcgt cctactagtg cttgtacacc acctgtattc ggatctaaag ctactgaagc
    27541 agattggacc atggcaccat ctgaagcatt tgctgggaat aatgcactgt tttgataagt
    27601 agcttctaat tgcttttgat aatcctgatc taaagctgta tagattttat agcctttatt
    27661 catgacatct tcttcatcaa gaccatactc gttaactgct tcatcgatca ctgcatcaaa
    27721 ataataagga taacgataac cagaatctga attatcgtat gtgtcattaa gatacgcgct
    27781 gatatctgtc tggctttctg cttgttcttg ttcttttgtg atttttccgt tttcttccat
    27841 tacacttagt actgtgtttt tccgatcatt cgcatttttt gggtgatcga tcggattata
    27901 aataccagga cctttcagca ttcctgccaa agtagcagcc tcagacagcg taacattcgt
    27961 tgcatctact ccaaaatact ttctggaagc gtcttggaca ccccataccc cgttgccaaa
    28021 ataggcattg ttaagataca tggtcaagat ttcttctttg ctgtacttct tttcgatctc
    28081 gattgccaaa aataattcct tcgcttttcg atcaaacgtt tggtctaatg tcagatacgc
    28141 atttttggca agctgctgag tgatcgtact tcctccgccc cctgatgttc cgccagacaa
    28201 gaccattcgg actgctgcac gggcaatccc tttgatatca aacccgtgat gctcgtaaaa
    28261 attcctatct tctgtcgaga ttactgcatc ttggatatag ggagaaatcg cgtttaattc
    28321 tacatatgtt cctttttggg cgtacagtgt gccagcttct tcgtttttct tatcataaat
    28381 gactgtcgat tggcttaatc ctgattttaa cgtttcgaca tttgcttgtt ttgctaaaat
    28441 aaagaggtag atacttgtca ctaagacaca gatcaaacca atcagcaaaa tcaatttgtt
    28501 cacatgatat tttttccaga tgcgctttcg ccatcgatgg aattgtccga gatatggtct
    28561 gatccaacgc caaaaactga tcaaagcagc ttttatcttt tctaaaatgc tttgaaaatc
    28621 catttgcttc ttctcctgtc tatttgattc aatcgtctta ttttaccata gtgaaagagt
    28681 gttttcttcc tgcttaagtt gtagttcaat atgttttttt acgttagtgc aagtagagta
    28741 acataagaat gaacagaaaa atgtaagttt tttcttaaat atgttttaaa aatggtacaa
    28801 ttagtctgcg attgcactga aaggagtaca cttgtgaaaa tcacgatcac tttacctatg
    28861 aaccatcctg aaacaacaat tcgcgacttg cttgaaaagg aatggttagt tcctagaaag
    28921 gttcgacact ttttgcgtat acgtaaaaac gtttggatca atcaacaacc tgctttgttc
    28981 catcatgaag taaagggcaa tgaccagatc acattgttat tcgaagaaac agattataat
    29041 tatcaagaag ttcaattagg agatgcgaag cacatccgtg ttttatatga agatgagcat
    29101 ttgattatag tggataagcc tgcaggaatg aagactcatc caaatgaacc gacagaaaac
    29161 agtaccttac tcaatcattt agctgcttat ctcgacacta aacagcaacg accttacgtt
    29221 gtccaccgct tggacaaaga aacaagcggt gccgttttat ttgcaaaaaa tccatttgtc
    29281 ttgccgatac ttggaagaat gttggaacaa aaaatgatct atcggagata tcaagccatc
    29341 gtatggggag aaattgccaa agatatgacc atcaccaata aaattggacg agatcgccat
    29401 gatcggagaa aaagggtcgt agatgataaa aatggtcaga gcgccttgac acatgtcact
    29461 gtcaacaaag tactttctga acaaacacaa gtctattgtg ttttggaaac cggacgtaca
    29521 caccagatca gagttcattt agctcataag ggacatccga tcgttggaga ccctctctac
    29581 caaaatagaa cagctgaacg actgatgctc catgcattag aactgcacat gatccatcca
    29641 tttactcaag aaaaaatagt cggtaaagct ttacctggat tatgggaata gaaataaaaa
    29701 agaacagagt cttatcagca gataatgata agactctgtt ctttttgtgt aatttgtctg
    29761 cttacttttg atgttcgtgt tctgctaaca gcaaactacc gataatccca ctttcattcg
    29821 gcagtcccca acgaacgata tattcactta cttgaggtgt ttccatataa ccacccatca
    29881 attcaacaaa ttgctgacgg attttttgaa ggagatgatc ctgattcatt accccaccgc
    29941 ctaaaataat cttttcaggt gctaacgtca acgtatagtt gatcagtgct tgagcaatat
    30001 aataagcctg aatagcccaa acaggatgat cttgcggcag atcttgccct ttgatccctg
    30061 tgcgtgcctc aatagacggt cctgctgcta atccttctaa acaatcttta tgataaggac
    30121 aagtaccttc ataatggtca tctggatggc gtttcaccca aatatgtccc atttcaggat
    30181 gtgcgatccc tgaaaaaatt tcttcattga tcacgacacc tgcaccgatt cctgttccca
    30241 cggtaaggta aatacaacta ttttttcctt gtgctgctcc ttgcttcaat tccccatatg
    30301 cagcagcatt gacatccgtt gtccaagcag caggaatatt gtagcgttcc ttgattgtgc
    30361 caagaaaatc gaattgtgcc cacccttttt tgggagttgc caaaacgtat ccgtaattat
    30421 cttttgtttt gtcgatacca atcgggccga atgagccaat cccgattccc ttcaattcat
    30481 aacgatcaaa aaattcaaat acctgatcca atgtttcttc tggtgttgtg gtagggatac
    30541 ttaatttttc taaaatttct ccaccatctg aaaccgcaca cacaaatttt gttccgcctg
    30601 cttctattcc gccatacatt cgttttcctc ctcgaatccg attgtccgaa tctcataagg
    30661 ttggattatt gggacaaccg cttgcttcgt tggttcttca agcagattca atatgacagt
    30721 ttttccattg tctttagtta tttccaattt ttctaaatga ctagacatat tgaaacctct
    30781 tactactact ttatcactaa acttgctgcg tttcaaagct gtaattgcaa acgtttcact
    30841 ttttatcgtt aaatattgtt gttttgaaat caatgttcct tcatgatgtt tgatttgttg
    30901 agtggaaaaa ggaatctgtg ctgcgtatgc atgcaaataa gtagagaatt tttcttctgg
    30961 tccatgtagt tcaatgctgt aattgaaccg atgctcacct agacactgtg cttctggtgt
    31021 tggaaaatat ccccaatcgc ctagttctcc cacactgcga agtagcgtca ctgcgatttg
    31081 tccgtcttct gttacttcat attcattcaa accaaagttt ccgactgtta caccgtactc
    31141 ttcatcatga atattgacaa atgcttgctg atgttgcgga ttcgtggggt tttcccaact
    31201 tttagacaca tggtttgggc gcttcaccac ttcaaaaata ctatctgctt cgtgatgttc
    31261 cacatgtaac tttgtaggaa acaagacacg taagcgatga tctttcatct gattgtcgag
    31321 agtcgtttca aagtcgattt ttttactatc ttttctgatt gtcatgattg tttttatttg
    31381 aaggattcgt ttttctttgg atcgttctgc ttttcgataa cgaaattcca caaccatctg
    31441 ctgttctttt tctaaacgct cgtctgcaga aacagggatt tccatttcct gtagaatact
    31501 tatttttgct atttccggtg tatctactaa tacttttact tcagagtttt ctttgttact
    31561 ggataggatt ggctgatcac agaaaggttg tttaaagata tactcatttc ctatatcgcc
    31621 gatatcttca aaaatatgca gattattcaa ctttcgtttg tttttgcgat cttccattgt
    31681 aatggtacca tttttttcaa tcgtcaaatg tagagggccg ttttcgatga ttcgtccact
    31741 ctgatgaatc attgtttcct tttcttctgc tttcgcttcc ccttctacaa gcgcgaatgt
    31801 ttcccaagaa aatgctggca tgttttctaa tggtaaagtc actttgatca ttcttgccat
    31861 atatggcaca cggaaacggt ctttcggcaa atcataacca aattggacag tttcttcaga
    31921 taaaatagct ggtatagtgg ccccactttt tgtttctaca tgatacttac gtttaggcaa
    31981 attttctaac tcttgatata gttgttcagg tattccttca gcgaatcttt ttctttctaa
    32041 ttcgatggtt atttctgcct caccagtttt atccattcct gcagtattta caatgacaaa
    32101 tggaaagctg tcttttggga atccggtcgt atcgattgct gcggtcagct gttctaagga
    32161 atcttgtgca agatactttc caacttcatc tgctttttca aaacgaggta tcatttcccg
    32221 atggacagaa tcgactgaac aaccgcaaat actgtcgtga ggatgatttt gcattaatgt
    32281 cttccaagca taatctaatt gatcatgggg atagtttcca ctaacttcat aagccatcgt
    32341 cgcaagtggt tctgtaatat tttctagctg tcgctggacc ttggtattcc attgttttaa
    32401 gtaaacccga gcagatgctg tattggctaa agtataccag ccatccgttt cttgacttgt
    32461 caattctcct tctactgagc ctaagtcttc tggcacatct ttttgaactg cttccagata
    32521 gtcagtaaaa ttagaatgaa taaactcgta atctggaaac agttcatttg cgagatggat
    32581 tgcttttgat atatcttttt gtaccggttg atgatcaaca ccattcatca tcaataagtg
    32641 gttcgtagag gcatattgtt ctgcatccgc taatttttgc ttccaaaagg caagagctgc
    32701 ttctttttct actggaatct cattcccgtt gctataccaa ttggcaaata gcagaccaaa
    32761 gattgctgtt tgatcaggtc ctttccacca catctctgag tattgggaag aatagttttc
    32821 tgcttccaaa acttgattat caaagccaat tggttttaca ccacggccaa acgctgctgc
    32881 tgaaatacca gcttgtttca ttaattgagg cgtctgtccc atatttccaa atgtatcggg
    32941 aaaatagcct aacatgacag gggttcccca tttacggctt tcttccatgc caatcagcat
    33001 atttctcacg ttcgattccg agctgataag aaaatcatct tgcaagatat aaaatggtcc
    33061 aattctcaat tttccttcat tgattgcttg ttggattgcc tgtctttttt ctggccttac
    33121 ttgaagatag tcatctaaaa taatcgtttg cccatccaaa tgaaaactgt tgaaggacgg
    33181 atcaacttca aatagctcta gtagatcgtc tatcaattca atcagtcgca tgtgatgctg
    33241 ttcgtaagcc atgtaccatt cacgatccca gtggctatga gaaatgatat atactttctt
    33301 tttcatttac gatacctcct acttttctac tctaatatca aagtaatcca tgactaattc
    33361 gcaaaacatc atatttgccc aagaaaacca ttctctcgta taattttcag gattgttcac
    33421 atcgaatcct tcgtgcataa ggtgtgttcc tgcgtcagtt gctacaagta aattcaatat
    33481 ccgctctttt tcagatttgt ctgacgttgt cattccttcc atagctaatg caatcggcca
    33541 aacgtatttt tctggcgtat gggaggatcc aattcctttt gcgtactttc cttcatagaa
    33601 atatggattt tctttactca acaatgttct tcttgtttgc agataatctt cctcttgttc
    33661 agaacaatat cccaagtaag gtgcggcgat cagattgggc acattactgt catccatgac
    33721 tgtggcgttt cccattccat ctacttcata tgcataaatc gtttgccctt tttgattaac
    33781 cgttcgtccg tgattctgaa tcccctcttg gatctctttc ttcaatttct gtgtttgctg
    33841 tacaatttct ttatcatcga gtatcgtttg aaaaatttct tccacataac ctaacacgac
    33901 caccgcaaac atattggatg gtaccagata tccataacgg caagtatcat cgctaggacg
    33961 gaaaccagac catgtcattc ctgtaaaagc tgtttttgca cctcgcccgt cattgatcag
    34021 cgtatcttct tttcttgtcg tgtctcgtac aaatgtataa ggagagtgtt catgatcttg
    34081 ctctgttttg aacacgtcca agattttttt gataccttca ataaaagatt gattgaattg
    34141 atcagttttt cctgtatttt tgtaaagaag ataggccaac tgtattgggt agcataaaga
    34201 atcaatttca tattttcttt cccagatcca atcgttcatt tttgtatgat ctgtttggtg
    34261 gccagcaccg ttagcttctt cgttgaaggc attcgcatat ggatcgatat tgatataaaa
    34321 aaattgcttt ttgactaacc cgctgatcat gtcagctaat tcctcatctt cttttgcaat
    34381 cactaaataa ggacgaactt gtgcagtaga gtctcttaac cacatcgctg gaatgtctcc
    34441 cgtcaataaa aaggtggttc cgtcattttg ctttttgact gttgtcaaca gagtattggc
    34501 aaatgctgct gtaaaattct ttgcccagtc cgcatggata tccccacatt tttgtgtgat
    34561 atcttccata aatttctgca ccgattttgg tatatcttta taagccacta ataaaacctt
    34621 ctttctattt gatatatctt taaagattat acttcataca gccaattatg tctacgcttt
    34681 caaaaaatat ctttttattt actttttcat ccattatggt attatttgaa tatgatatat
    34741 cattaagagg tgtttatatg aatcaaccat tgtaccagac aatatttaat gatttgcaaa
    34801 cggctatttt aactggtgaa ttacctgtag acagccaact accaactgaa aaagaacttt
    34861 cacgtaccta taaagtaagc agaatcactt ccaaacgtgc attgactgaa ttagagcaat
    34921 taggacttat ttatcgcgtt cgcgggaaag gcagtttcgt taaatccgct tctccggaac
    34981 agattcttgc ttctcctaca aaaacacgac ggattctgtt tcttcttcca tatgtcgctg
    35041 atttgtctgt tggtgatttt agcaagggat tgaaccctgt gatgcaagat aaacagattg
    35101 atgtcatgat gacgacgctt gactttctac aaaataaaac agcaaaagag ctaatcaatg
    35161 aatttgacgg attgatttat tatgctcttg atacagaaca acatcttgac ttactttttg
    35221 agctttcatt gaaagaattc cctgtcgtca tattagataa aaaaatctat gagttacctt
    35281 ttcctaccgt tctttccgat aatttccaag gcggtgcgct tgctgcctct tatttgatcg
    35341 aacagggaca ttcaaaaatc gcttatttgt ttggtacgca gactcatcca caatccgttc
    35401 gacagcgtta ccttggttac cttgaagcat tggacaaagc tggtttgact ttccacactt
    35461 cactggatga caaaagcgcg acattagatg aattgctttc ttatatcact aagtatgaag
    35521 taactgcttt tgtttgtgaa aacgatgttg tcgctatcca gaccatgaat ctcttgagac
    35581 agcatggtta tcatatccct gaagattttt caattatcgg atttgatgat atccaagcag
    35641 cagctcttgt tgacccgcca ctgacaacca tcgcacaaga ttttgaacag ttaggtaagc
    35701 ttgcgggaga tgctttggtc acttggttag agacaaaaga tcgaccatcc gatagtaaat
    35761 ttccagtttc attcatcaaa agacaatcaa caaaggagaa ataaaatgaa tatcggtcaa
    35821 atagatacta gacatgcaac agcgaatcag ccaaatttct ctaatgggaa ctgccagcct
    35881 tatactggcg ttccttttgg gatgaattat tttgcaccgc aaactacgga tcaaaacggc
    35941 agctggtggt ttcatcctga tgaccgcgtt tttcaaggct accgtcttac ccatcaacca
    36001 agtccttgga tgggtgattt cagtcatatg ctgtttacgc cgatcaatgg aaaactacag
    36061 gagaacaccc ttttccatgc tcaaagttct taccgcccag aagaaagtat attttgcccg
    36121 actcatctgt cgatctgtca attacgttat ggcatctgtt ctacattgat acctagcatg
    36181 tatggcggaa tcttatctat tgattacagc aaaaatgaca gcggtttact tttatccttt
    36241 ccgggacgcc atcagctctt tgttatagat ccttacacag tggaaggaaa aatcacacat
    36301 tttgctggtt cagaagatcc tgatttttct ttttatttta tattgagatt tgaatatcct
    36361 ttaacaattg atgagttagc tgtttccaac aaaaatagcg actcgatccc gttgtatttt
    36421 gaacagacaa aaaaacaaac tatccgattt gggacatctt ttatcagctc ggaacaagca
    36481 gcttataacc tggaactaga acaaaaccaa agcaaagaga cttaccttgc tcacagtcaa
    36541 gaacaatggc agtcctattt tgatcgtata cagctcacac accatgatca acaacaattg
    36601 cggacgtttt atcataattt atatcgggtg tttttatttc cacaaacatt ttatgaaatt
    36661 gatcctagtg ggcaaaaaat ccactatgat acgactagtc gatctataaa acctggtgtt
    36721 ctctatacaa ataatgggtt ttgggatacg tataaaacgg tttatcctct ttattctttg
    36781 attgctgtag aaaaatacga agaaatgctg gaaggttttt tgaacagcta tagagaaagt
    36841 ggctatttgc caaaatggct gtctcctgat gaacgtggac ttatgcctgg gacattgatc
    36901 gatgcggtca ttgcagatgc tgctgtaaaa gatatccgac gagacttgat gcctgaattt
    36961 ctaacggcaa tggaaaaagg tgctacggtt caaagcaaac atccaaatta tggacgccaa
    37021 ggaacagaag attacttgac atatggctat gttcctaatc actaccacga atcagtcaat
    37081 cacacattag actatgctta tagcgatttt tgtattagcc aagttgccaa ggtactagaa
    37141 gaagaggaaa tgacgaagaa atatcagcag caatcattga actatcaaaa tatctttgac
    37201 tatgagtcag gatttatgcg ttcaaaagat aaagatggca agttcagaga accattttca
    37261 gctaatcgtt ggggacaaga ttatgcagaa ggaagtgctt ggcaaagcag ctttgctgtt
    37321 tatcacgatt tttcaggact gatcggaaaa tatggtggca gtgagagata taaagaaaaa
    37381 ctcattgagc tgtgcaatca gcccccaacg tttgacccag gaggatatgg ttttgagatc
    37441 cacgaaatga gtgagatggc cgcgatagaa tttggacaat tagctatttc aaaccagcca
    37501 agttttcact atccttactt gttcagttat ataggacaac ctgaaatggc acagccactg
    37561 cttaaacagt tgatgactca gaccttcgac gattctccaa tgggttaccc tggagatgag
    37621 gacaatggaa gtatggccgc ttggtatatc ttcaatagtc tgggatttta tcctgtcacg
    37681 cctggaaccg gtgaatatgt tatcggtatg ccattaattg acaaggctgt tttgcttttg
    37741 tcaaatggaa aggaattgac gattgaagca acgcctaatc ggccgcagca acaatttatc
    37801 cataaaatca aacggatgga caaagaatat acgaaattat attttaccca tcaagatttg
    37861 ctgaaaggcg gcacgatctc ttaccaatta gggatcatcc ctcaccctaa gaaatatcaa
    37921 gcaaaagatt tgcctttttc cttatcaaac tataattaac aagaggttgt gaaaaagctg
    37981 tcctgcatca agtaataaga acagccaagc aaaaatagat cctcatattt ttcgtttggt
    38041 tggtcttatt accgcagatg caagcttttg aacaccgttt attgagaggt tgtgaaatca
    38101 gcgttctgac ctgagtatta gagagacaaa tggcaaaata gttcctcata ttttgccatt
    38161 ttttgagcta ataccgaggg tcagctgatt gaacaccgtt tagtggagag gtcgtgaaaa
    38221 agctgtttag tttcgagtat taagaaaaat tttgtgaaaa tggctttcca catttttgca
    38281 taaatttggc ttaataccga gaaactggct tttgaactcc gtttatcgag aggtcatgaa
    38341 aaagctgcct tgcctcaagt aataagaaca gcccaaaatt agatttctag acaatttttt
    38401 ataagttatt tcattacatt ggctttttct tttatgattc tccactgttt tctcggtact
    38461 ctttagggga tctgccgacg attttcttga ataatttaga gaaatacgtg gtgttgttgt
    38521 agccaatctc acttgctatc tcattgatgt tttgattact gtgcaaaagc agttgtttcg
    38581 ctttttccat acgtaaatgg ttcaaataag ctgaaaaact ttttttcgtt tcttttttga
    38641 acagctgtcc tagatacatg acatttaaat gcaggttttc tgacacttct ttgagtgtaa
    38701 gtggttcttg ataatgctgg tgcaggatta cgattacttt ttccacattg tcactgtact
    38761 ttttctgtct ctgatgcttt ttgatgaatg acagaagtag ctgctgaagt tcttgcaccg
    38821 tttttgcctg atggattttt tcgattcctt gtaaatattc ctcatcttcc agatcaatca
    38881 attcccgttg aatctccata aacagtaaaa aactggaata tcgtatatct tccggcatca
    38941 tggctgctaa ctgaaactgt tcaaaaaaat cagtgatcat tttttgagcg acttctaatt
    39001 gtttattttg cagcacgcgt ctgaaacttg aaaaatcgat ggtttgatct tttgtttctg
    39061 cttgtactgc gtaaaaaaca tgctcgtctt tatctccata aaattgatgc aactgtagat
    39121 tgtctttcgc ttgttggaat gtttcaggga ttttgtccaa agaatctgtc tcttccccga
    39181 tactgatcag ccattcctga tcaggaaagt tttcttgaac aaaacaacag aagccatcaa
    39241 cttcatctgc ctccaacaac aacgtgatca atacacggtc tccgtaattt cgttgatagt
    39301 aaaagatttg ttgccgttct tgcaaccatc tattgataag agtatcatga gttcttgcca
    39361 gttgaatcaa tactatccta tgctgcttct cacttatttg tcctattatt tcttcttcac
    39421 ttatttcatc caattcttca ttcaaccatt gactgaataa cagttcttga tagatttctt
    39481 gttgattttt ttgttcattt tgctgatcta accgtgtttt gattttcttg aggctttcaa
    39541 ccaattcgaa cttattcacg ggtttcatca aataattcac ggcgcctaat tgcatacctc
    39601 ctttcaaata atcgaattct tggtatcctg ataaaatcat aaattcaaaa ttatgacgtt
    39661 ctttttgagc cgcttcaata aattccagtc catttatttc tggcattgtc acatccgtta
    39721 ctactaaatc aatctgtcgc tgttcaagta cagctagtcc ttctttggca ttctctgctg
    39781 ttgctactat ttgaaagcct aaactttgcc aatcaattat cttttttaac ccattcaaaa
    39841 tcatgtattc atcatctacc aataacactt gatacacgct catccctcct tgaatgtaat
    39901 agaaacggtc agtccacctg tctcattatt ctcaagcgac atataataac tgctgccgaa
    39961 gctggcacgt aaacgttcat tcacgttttg cagaccgata gaaccgtgaa gttccacttt
    40021 aggatgagac agtttttctt caatctgttt tagccgtttt tcagtcatcc cttttccatt
    40081 atctttgatg atgatcctta cccgtttgcc ttcctgcaag actttgacac ttagcgcatt
    40141 atcgaatcga gtaaaatcaa taccgtgttt aaaataattt tcaactaatg gctggatcac
    40201 aaatttaggt acttcgatct tttccaaatc aggatcgatc ataaaatgat aggctactcg
    40261 attaggataa cgcatttgat acaaatagac atatttttcg caaaagtcca gttcttcttt
    40321 taaagtgatc gttttctctt gattcgtatt gtttcgaagc aaagcggaaa acgcatacac
    40381 aacatctgct aattcttcac ttccttcgct gattgcatac attcggatat attctaatgt
    40441 attatataaa aagtgtggat tgatctgtgc ttgaagcgcc cgcatatgtg cgtcttgctg
    40501 tttgatttct aatttgtaga tgtcttctac aaactgattg atgctatcca acatttcgtt
    40561 gataccgatt gaaagttcct tcagttcata ttccgtgttt gttatgtcga tccgcgtctc
    40621 taaattccct gctgctgttt gatccatggc ctgcatgacg atagatactt gctgtgaata
    40681 tcgtttgaat gttttataaa gaaagataag cagtatattg tctaaaataa tgataccaat
    40741 gatcagcggg gcaagatttt ttcccgtttc gatttttaca ctttttttat ctagtacagc
    40801 taatatacga taatcatcag acagttcttg gtgttgaaca aaattgtttt tttccagatc
    40861 gtcaatcggc aattgtgaat ttttcttcag actctctgtg atgatcattt cttgtctttc
    40921 aaacgtttct ttagctattt tattatcatg gaatgtgtat agtcgatttg tcgttccaga
    40981 aatcatgtat aaagagagtc cattgaatga cgttagattt tctaaaatca tatctagttc
    41041 tttcttttga aaaccaataa aaatacttcc tgactcagct cctccttgtg tgataggcaa
    41101 cttgatataa aaggcgtcta gtaattttgg tgtccccttt tttatttccc cacctttgtt
    41161 ttctctagaa gattcataat actccggtag ttgattcaac acgatatata tcgcacttag
    41221 ttcttcataa tttgcgtaga gatctttgat ttgatttggg aaagaaacta attcatcggt
    41281 actgttttgc tgttcgtata catacatcag atactgatct atgggttttg ttaagtaggt
    41341 cgtcacattt tcgatctttt cggaattccc tacaagctgg tttttgatga tcctactcaa
    41401 ggttgtttta tcattcagca ttctgcttgt gctttgaacg gcatcacttg tcatgttttc
    41461 tgcctgtttt tgattttgtt cccaagtatg gatactaaaa ataacggtag cagtcatcgt
    41521 tacaccgatc atgataaccg cgtatttccg caacagacga tttagtaagg ttccttttga
    41581 aaatagaatc cgaaacttat tcataacttt ccaactgttt atctaattct tcacgccaat
    41641 gtgttgtcat cgtaccattc caaaccgtca aaagaccaat gacaccaaac aggatcaatc
    41701 ctttgaattg ccaagtcacg cctaaaatta taccgctacc aataattatt tttagaaaag
    41761 acgaaaagct ggaaaaaacc gaaataaaac ttagctttag cagattagga acagagatcg
    41821 tatattcact atctaaaatc atactgtatt gataagtagc aaataggcag agcaaggcaa
    41881 aaagtaaaat aaaatcaata gctaaaaaaa tgagcccttt gatttgaaca gataaatata
    41941 aattgtaact caataaagca gtaccagata aaaataaact aaatagcaga ttgcctctta
    42001 aaaaatttct tttatatata ttccagcctc tttttattgt gatttcttta tactcgaatc
    42061 cgtacaaata aaatagttca ttgactgttt tccatgccgc acctaatcca aagatgatcc
    42121 cgccggcaaa tgtatatatc cagaaataca aggttagttt tataatgacc cagatccgga
    42181 taaataactc ttccaaaacc ttccctaaca tatcttctcc tccaaacatt aagtttatac
    42241 tttctcatta tacaaaaaaa ggttgggcaa tcagcacctt gacctgatta ttagagaaac
    42301 aaacggaaaa atagttcctc atattttgtc gttttgtgag cgaataccga gggttagctg
    42361 attgaacacc gtttaccaag agtttgtgaa atagccgctt agtttcgagt agtaagaaaa
    42421 attttgtgaa tatggctttc cacattttta catatattta gcttaatacc gagaaactgg
    42481 cttttgaaca ccgtttattc ggaacaagag gttgtgacac gtcttttgtc acaacccctt
    42541 tgtctttatt cattattatt cttgtcggaa ctcatcatat tgtttttgca tttctttcaa
    42601 taccttatca tagccagcct tgtccaaagc gtctttcaat ttcggtaatg tttcatctgg
    42661 atcaacagtc cctgtattca atccatctaa atattgattc atgacattag aaatattact
    42721 taattctgtt ttgacactgt cagtgttgaa gctgaatcct aaaatcggtg aagtttctgc
    42781 atcagcaatc gattgatcac gtttggcaat catgtcatcc gtaatagact cttgtgtata
    42841 tagaatcttg ttgtttcctg tattccaagc agacatatgt gtatttggct gataaccatc
    42901 tagcaatttg attttatcat ctgaaccatc gactttttcc catgcttctc cctcgatccc
    42961 ccaaacaagc ccattcaata attctggatc actgttaagc agccctagaa gttctactga
    43021 tttttcttta ttttttgaag tatttgatac gacaaaattt gccatttgtg cttgagctgt
    43081 agattttagt ggaacagtaa ttgcttttga gacaagttct tgttttgctg catttgtcaa
    43141 aattgtatcg ccataatcat acggtccttg tgtttctcca cgcattagcc aagtatttcc
    43201 ttctagtgga taatccttat tgctcgttgc agcgtcactt ggaatgagtc cttgtttgta
    43261 ccagctatgc attgtacgta acagtccgat atacgtttca ttatcgtatt ggttgatgat
    43321 tttcgaatca tctccatcca gatcaatagc aaatggtaac gtattcccta aaggataatc
    43381 aaagttccct tggactttga agccttgtcc aatggcaaaa gctgccgtgt ttggttcttt
    43441 ttcatggaat tccttcaaga ctttttctgc atcagcgtaa gattggattc catcaattga
    43501 aagatcgtat ttatctagta aagctttgtt aaaagtaagt acttgttgag caaagacatt
    43561 tccattgact gggaaagcat ataattttcc attgaccaga tttcctttaa tatatgcttc
    43621 atctaaatca ttataagctt tttcagcgta cttaggcgct aattcagtca aatcagcaaa
    43681 ggctcctttt tgggcattgg aaacatagtt gttcgcaaag gcgatatcat aattttcccc
    43741 ggaagaaatg atgacgttca ttttcttttc gtaatcgccc cagccaatgt aattgatatt
    43801 gacttttaca ccgatctctt tttcgattcg tttgtttgct acttccatca attgatcgaa
    43861 attatctggt ttatctccga tttgatacat ctgcaaagtg tccgaattgc tagcttctgc
    43921 ctggtcttta gaaccagaac ctccgcatgc tgctaatgtt cccaacaaca acgctgaaac
    43981 acctgtaaag gctagtttct tccataactt catttttctt cctcctaatt ttatgattta
    44041 tatttttgtt tctttattct tttactccgc cgattgttag acctttgaca aaatgcttct
    44101 ggaaaaatgg atagctgatc gcaataggca acgtcgagat gactacgatc gccattctgg
    44161 cagattctcc tggaactgag gctaatccgc ctgtcaattg gcttcctgct cctgaatttt
    44221 gtgtcagata ttgaatatta ctttggattt tcatcaaaag atactgtagt ggaactagct
    44281 tatcatcttg gatgtatagt aaagcattga accagtcatt ccagtaaccc aatgcggcaa
    44341 ataaactgat tgtcgcaata cctggaacag ctaacggtaa aacgatctga acaaatattc
    44401 gcagttcgct agctccatcg atccgtgccg attcaataat cgaatcagag accgaacgtt
    44461 taaagaatgt gcgcatcaca ataatattga agggactgac agccattggc aagatcaatg
    44521 cccaaatcgt atcttttaac tgaagaagat ttgtcataac aagataattg gccaccatcc
    44581 ctggtgagaa caacatcgta atcaaacaaa aaacggtaaa aaaacgacgg aatggaaagt
    44641 ttgaccgtga aatcgcataa gcatataaag aagtagccgt gctattgatc agtgtaccta
    44701 aaacagtaac aagtacagtg acgaaaagcg cttggaaaat tttatcctgc atctggtcga
    44761 acaagtacgt ataaccaaat atactgaact tttctggcca aaaactgtac ccgtgagtcg
    44821 acaatatgga ctcatcggta aaagagatgg cgataacaaa tataaatggc aaaatacagg
    44881 aaatagcaaa gagtgcaatc attatattag agaaaaaatt agccgtctta ttgaaagagc
    44941 ggacttggac tctctccact ttcttttttt tcattttttt cctccttaga ataatgcaga
    45001 atcgctatca aaacgtcggg cgatcgtatt tgtgatcatc aacaagacaa agccgacaac
    45061 tgattggtaa agtcctgcag cagccgtcat accaaaatct cctgtggatg tcaggccatt
    45121 gtagatatac gtatccaaaa cttgagtcac atcatataat gcaccggaat tcctaggaat
    45181 gttataaaac aggccaaaat cagctcggaa aatgtttcct acggctaaaa tcgttaaaat
    45241 cgtcattagt ggaataagtt gtggtatcgt cacatgtttg atctgctgcc atttgctagc
    45301 tccatcaacc atagcagctt cataataagt cggatcgatt cccataacag atgcaaagta
    45361 aataatgctg ttataaccaa tccctttcca tgtaccaatg aacaccaaga taaacggcca
    45421 atatttcggt tcattatacc aattgacagc ttctcctcca tgtccagtga tccactgatt
    45481 gaatattcct ttgtcaggac ttaaaaaagc gtaaacaaag taactgataa tgacccaaga
    45541 tagaaaataa ggtagtaagg acatcgtttg ataaacttta acgagtcgtt tatttctcaa
    45601 ctcgctcata atgattgcaa atacgactga gatcagcaga ttcaaaagga taaatgctac
    45661 attatataaa attgtatttt tagtgatgag aaatgcttga tccgaagaaa ataaaaattt
    45721 gaaattttcc caacccaccc aaggactttc cctcaagcta gccaagaacc catctgctga
    45781 aatatgaaaa tttttgaatg ctacgacatt cgccattaca ggtatgtaaa agaaaaaaat
    45841 catccaaagc atacccggta cagccatcag gacaagtgct ttataacgcc atagattcat
    45901 aaaaaaatga ttgaacccct ttcgtttttt catctaaaaa cccctttcga ttcattcgca
    45961 acgtaattat agcgctttca ataatgagaa taaataaaca aagtataggg aaaatgaaac
    46021 aaagtatagg agaggttgtg aaatcagcgt tttggcctga gtattagaga aaaaaacggg
    46081 aaaatagttc ctcatatttt gccgtttttt gagctaatac cgagggtcag ctgattgaac
    46141 accgtttatc agaggttgtg aattcagcgt tttggcctga gtattaggga gatcgtgtcc
    46201 ttactatcta actctgagtc acaaggaaca atggggactg taacaaaagt cttgtcacag
    46261 tcccttattc cgaacaaacg gtgttccaga agtagcttct acggaaataa gccgaaattt
    46321 cacaaaaaag ccatccgaaa gtcagacgga caagtctgct tttcagatgg cgctacaact
    46381 actctgctta ttcttttagc tatccattca attatttttc tctcacttgt tctagctctt
    46441 ctttggtcat gggtcgatat tgccctttat tcaaatcttt aggcagccaa aattttccca
    46501 tacggattct ttttaaatat aagacttctt ttcctactgc tttgaccatt cgcttaactt
    46561 ggtgaaactt tccttcatgc aaaatcagac ggataattga agtttctgtc tcttgatcta
    46621 cttgatcaat ttggagtttt gccggcaatg tctgctcatc gccatcaata atcagtcctt
    46681 ctgcaaataa acggatatct tcttctgtca ttataccgct aacctcagct agatattctt
    46741 tctccacatg ttttttaggt gatagtaact gatgggcaaa caccccgtca ttcgttaaaa
    46801 tcaagaggcc ctctgtgtct ttatctaatc ggccgactgg aaaaagatct tcccgataat
    46861 cctggtcttc caataaatcg attacggttt gatcatgatt atcctgagta gcagaaatga
    46921 ctcctgcagg tttatgcaaa atgtagtaaa aatctttttg atacgtaatg atttctccta
    46981 aataagtaac cgcatcttcg aattcattta cttgcgcttt atcgcttttc accacttgtc
    47041 cattgacttc gatcgttcct tttttgatta atcctttgac ttctttgcgg ctgccaagtc
    47101 ccatatctgc taaaaactta tctaaacgca tgcgtttccc ccatttcaaa agagcatcaa
    47161 tctagctctt ctgattcact tattttattt ttaatttatg tcgtaaacgc gctattcctg
    47221 gtcctagtag tctttctgcc aagcggattt tcaaagctaa ataaccatac actaaagccc
    47281 ctatacctgc tactacaaga atcaacaata gagactggaa tttgctatct tcgtttaaaa
    47341 aagcaccaaa aatcatcttt gtgatccacg aagccaaaag cataatcaag gtaagaataa
    47401 agatcagcaa tgtcctgcgc cagacaaaac ttggtttaaa gcgggctact tcatggattc
    47461 tctttaagat caaggtacaa gacacagcaa atccgatcat tgtcgccaat aaagggccgt
    47521 atacttcaaa taaacgaatg gctgggtatt gaagaaggag tttcactaga aacccaataa
    47581 ccaaataatt aattgccgcc ttgttttcaa acattccttg cagcatgttg gaaactagca
    47641 tatatagtcc taggaagagt cctacaaaac ttgcttggat cagtacatta cttcctagag
    47701 aatccggtgt ataaaataat gtatttagcg gataggcaag taacataaca ccaaatgtcg
    47761 ccggaaacat aaaaaatgaa aacaactgta aatttccgct tgtcaatttt gccagaccta
    47821 ctcgatcttt caacgtaaca gcttctgtaa tcaacggtaa cccagtagac gcgatcgatg
    47881 ttgccaatgc aataactacc atcgtcaact tatctggatt ggcactaaaa atcgaaaaaa
    47941 gatccagtaa ctgtgcattg gaatactcgg tggatgcaga catgatcttc ataaaagtga
    48001 actgatcgac taatttgaag atcgttaccc ctgaacccac aataataaac ggaatcgctt
    48061 ctttaacggt atctaacaac aattccttcg ttgcaatatt tattttgttt tcgctgtagt
    48121 gaataaacgc cgatgtatac gcttgatgtt tcttcaaaaa atacaaaagg acaagaatac
    48181 ttgctagcat accgataaat gccgcgaaag ttgattgcgt gaccgccgtc acatagtcac
    48241 catccatgac tttcatgatg atgaatgtag ccaatagcat ataaaaaata cgtgccacct
    48301 gttctacaat ctgcgacagc gcataaggca tcatttcttg attgccttgc aaataccctc
    48361 gtatcacact catacaagga aaaaccaata cagcgatact caaagaacgc atcgttggaa
    48421 tcagttcttc tccgccacca gaagcatgag ctagccaagg agaggcgatg tacatgaaca
    48481 aagcaaacaa caggcctaac ccgcccatca tctgtaatgc acggataaat aatcgtcgtg
    48541 aagtgccata ttcattcaat gaattatagc gtgcagtttg ttttgcaatc gcagcaggta
    48601 ttcctgctgt agagatcagt agaaacaatg catatatatt gtatcccata ttgaataatc
    48661 cattggcagc cttagcattt tcgcccatcc aagcatacca gggaatgata tagacagcgc
    48721 ctagcaatct tgaaatgata ttactggcgg tcatccaagc agagcctcgt gccatttttt
    48781 cttgcggtgt taattgatct aatgctggtt ttctttgatt atccatcggt cagattccaa
    48841 ctttctacaa aacattacta tcattttaat tggtaaaaca gaaactggca atcgatttta
    48901 tataactttt ataagaacaa ttgttttttt gaattcggtt tcgttttttt ggtaaagtaa
    48961 agaaatatac agccttttat ggctaacatt tataggagat atcaatgaca caagaaataa
    49021 aaaaactacc cgttatattt ttaggtcttt tctttatcac agttggattg aattggttct
    49081 tgctccctca cgatatagct tccgccggag tgggcgccat cggacattta gttgaaacgg
    49141 ccttttctat ccaacgctca gttactgttt ggagcatcaa tcttatgatg ctgcttctag
    49201 ccgctgtcct attaggaaaa tcagtatttt ttaagactgt agcgggaagt ctgctttttc
    49261 ctgttgtttt agagattgtt ccaaaagtgg aaatgatctc ctcacatttc ttttcactga
    49321 tttcaggaag tcttttgttc agtcttgggg tttacacatt gtacacagtc ggggcctcaa
    49381 atggcggtat aacgataccg ccgattattt tccacaaatt ttttcggctt ccaatgccgc
    49441 aaggactttt acttaccaat agtcttatcg tctttttgaa ttattatgtt tttggattgt
    49501 tggagacact attcgttctc ctatctatta cagtcagttc attgtttatg aaaatactca
    49561 tccgcttgtc ccctgtgtca agaaaatttg aataaagctg gattttgtca tagcggaaac
    49621 aaacgatata ttaaaaagag tgtgctataa taaaccaaga aattgaataa agcgagggat
    49681 caatcaatga gcttctcttt agaagacatc cgtcatttac tattaaaaga aaatctatta
    49741 aaagaatttg tttcaacaag aggctggcat cttgatgtac cagaaaaagc tgaatttctt
    49801 cagttaagtt atgattcaag aaaagctgat gcttctactt tgtttttctg taaaggaatg
    49861 aatttcaaag aagaatattt ggattcagca atcgaacagg gtattcaata ttatgtatca
    49921 gaacaaccat acgaaaattc agcagtagga atcatcgtaa cggatatccg taaagcaatg
    49981 gcgcttcttg ctatggcttt ttacgactat ccgcaaaata aattgaaagt gatcggattc
    50041 actggaacaa aaggtaaaac aactgctgcg tactttacaa aagcaatctt ggatcacaca
    50101 acaaataaaa aaacagcatt gctttctact atgaatacaa cgttagatgg caaaacatat
    50161 ttcaaatccc atttgacaac gcctgagtca ttagatttat atcgtatgat gtcagaagca
    50221 gttgaaaatg gtatgactca tctagtgatg gaagtttctt cacaagctta caaaacacaa
    50281 cgcgtatacg gcttgacttt agatgtcgga atcttcttga atatctcgcc tgaccatatc
    50341 agtccgatcg aacatccgac atttgatgac tatttctatt gcaagcgaca attgatcttg
    50401 aattcaaaaa cagttgtttt aaatcatgaa agtgactatt ttgatttact tagggaaaca
    50461 gccgatctat tccagattcc aacgatcact tatggtcgtt cggaagaaag caattatcaa
    50521 gtgatccgtt cagataaagg tactcacggt tttactttat cttctcatga agatcgctta
    50581 gctatctgcg atactgctta tgatattttg ctggctggag gattcaacca agaaaatgca
    50641 gccagtgcga tcattgccgc agcactaaca ggtgcctcca gtcaagatgc acaagacgga
    50701 ttaaaagaag ctcgtgtacc aggccgaatg gatcaattga tccaatccaa tggagcgcat
    50761 gtctatgtgg actatgcaca taattatcta agcttgaaaa cattgctgaa atttgccaaa
    50821 aatgaacatc cagatggccg tgtaattgtt gtattaggca gcccaggaaa caaagcaatc
    50881 tcccgtcgac atgattttgg aaaagtgcta tcagaaacag ctgacatcgc ctttttgacg
    50941 gcagatgacc cagcatttga agatccgaaa aaaatcgcgg aagaaatcaa tgaagcaatt
    51001 actaatccag atttgatcgt tcattatgaa atggatcgtc ctgaagcgat tcgacgcgct
    51061 ttagcagaaa gcgctccgca agattcagtc gttattgcgg gaaaaggcgt ggatccctat
    51121 caaaaaatca atggtgtaga tgaaccttat gaaggggatt atgcaatcgt gaagcggttg
    51181 attgaagaat aatggtattt atatactagt ggtttcccat ttctaagaaa aaaagggact
    51241 gtgatttttt gtcacagttc cttttttctt agaaatcatt ttaacttttc actagctaat
    51301 tctgctgcct tttctctttc ttcatttaat aatttattat catagaattt gataaatggg
    51361 aaccagataa tgaatgcgat gattgcacaa atgactgcta acacagcagc tttccaatca
    51421 ccaccactac caacaaatgc tccgatcccg actggtgaag gccacggcat ctgtgcaagc
    51481 atcggtttga cgatttccag ccgaatggca aaataagcga gtgtagcaga agccatcgga
    51541 gctaagaaaa acggaaccgc taaataggga ttgtagacga ttggcatccc gaaaatgatt
    51601 ggttcattga tattgaataa tcctggtaca agtgaggctt ttcctaacac tttcagctga
    51661 tcagatttcg cgaggaatgc aataaagatg atcaatccta aagtcgcacc tgatccacca
    51721 acggttacat aagaattgtt gaattctcct gccaacggat aatttgcgcc ttgtgcgtta
    51781 gctgccatat tagctaatac gatcggggtc aagaaagaag tgatgatatt cgctccatgg
    51841 atccctacga tccacaatgc atggatcaag aaataaatca ccatgacacc aagccatgta
    51901 ttcgtcaact gcgtaacaaa cccaaatggg atagcaatca ttttgaagat atccgttcct
    51961 agtgcaacta ataatccatt gatgatcatc accacaaacg caatgacaaa tgttgggatc
    52021 agagcagtga aagaacgaga aactcctggc ggaacaacat ctggcatttt tatgacccaa
    52081 tttctcttga cacacataca atacaattcg accgcaataa tcgacataat aatagctgta
    52141 aagattcctg aagttcctaa acgttcgaca aaagagccca tcctaatacc atttactaca
    52201 gtttctgtct cattgataga agcaatcaag ctgattttac catcagtcat gatcaattca
    52261 gggatacaca taaagaatgc aaaaacagat agtaatgccc ccgtgagcgg attaacattt
    52321 aatttttgtt catctcgttc aattgacgtt aattcataag caaacacaat ggcaaagtaa
    52381 atagataaaa tccccatcgt cattgtattg acgatcatgt acaagtcact aactttgaaa
    52441 aaagttgcat taaaaaatcc ttctaaaaat gggaacggta atggcaaaat atttaaaacc
    52501 aaaaacatcg agcctacaat cgtgaaagga atagaagcca tccccgctgc catgacagcc
    52561 cgaacgattt taagttgcgc aattttcccc ataggtccca tcaggtattt ctgcaaaaaa
    52621 tcaaacatta gttattctcc tttcctaaat ataacgcttt ttcatattgt ttaatacgga
    52681 tatactgttg gtcttggttg agtgaaattt tctttaaacg atactgtata aatgcactgg
    52741 caaaaatacc gcttacaaca agaatgaaaa caaataactg tcctccattg ttatttgcca
    52801 taaaaggata caagaatgta aatcctgagg taaacaacac tggaatcact aataaattaa
    52861 agacactctg gaacaaaaaa taccactttg tccatggaac gttcgtttgg tgttttcgat
    52921 aaagctttac ttgttctcct actgcaggca aaatagctaa aatcagaatc atcggtaaac
    52981 tacttcctaa acttttagct gatagaagca gaatcatcca ttgcatgttc atgaaaaaga
    53041 aaaaggcagt caggtaacgt acgattagat aacgattgaa atacatgttt ttcaaactaa
    53101 gttgcttttt ttctaattcg attttccttt ttactgtatc ctgcacaatg atccttcctt
    53161 tctatttatt tttttgatac aaataattca tttcctgtgc aacttccaat aatgtcatcg
    53221 tcgtcatcag atgatcttgt gcatggacca tgataatttc catttctatt tttgtcccgc
    53281 tggcatattc tttcagaagt tgagtttgtg actgatgcgc atgaagaatc tcttcatttg
    53341 cttgtcgcaa cttctcttct acttcttcaa acatctcttt acgcatcgag cgaaatgctt
    53401 catgtatcag tgtccgtgca tttccgctat ggaaaatgat atcaaaagaa gtcacttgta
    53461 gtgtttcact gtttattttt tcagccatct gttttcctcc ttattcgatc agtttgataa
    53521 atttactgct gaaattctca aaaataggtt cagctaagat ttcctgctgt acttttagct
    53581 ggtcaactaa cctaacgatt gctttagtca cgaccgtaat tccttcattt tcgacataag
    53641 aaggcgaaac taaaaaaaca aaatgaattt cttgatattg atcccactgc atcccagaag
    53701 gaatcaatgc aacggctacc tttgtttcga ttccaactgg aacagcggga tgtgggactg
    53761 ccactgtatc actgaatatg atttgtccca tattttcacg ttgctggatc tgctttcgca
    53821 tttctcttat atatccttct tcttcattta tgctcagctt ttgcagcaaa tcatgaagaa
    53881 tttcttcctt tttcggttcg tacgtataag tcttgaaaaa tttttcagac aactgttcgg
    53941 tgtaaatctg ctttttttgc tgtagagaaa atgctggtat cggtctatct gaggaatgat
    54001 agggtataga ttctccaact acctttcgta ttttacgaac atcatcttca ttcaaaaaaa
    54061 tactgacatg taaaactgga attttgaaaa acattgtcga aagatcaata gaagaaataa
    54121 tcaggtcgat tccttttaaa gttgtttcat tgatctcata atagcctttt acacttacca
    54181 ctgtaatatt tttaccgaat tcactgacta cgcgattctt taatagttgg gcactgccgt
    54241 aacccgttgc acagataatc aatgcatgta gtttatgcgc agctctttct ttttccaatg
    54301 ccgccatgag atgcaaagcc aaataggccc attcatcttc attgatggta tagtttttca
    54361 aagccggcat gttgctgaaa tgccttttta ctgcgtcaaa gactttggga ttttctttct
    54421 ttatctcctc agtcaatggg ttctcaatgc gaatacctcg gctcaatcga atcatcatcg
    54481 gtgacaaatg atcgagtagt ccattgaaaa gctggagatc ctctactaat gaaaaatgaa
    54541 attcctgaga caatcttttc agaactttcg ctaattcctt tgatagttcc tgatcatttt
    54601 gattttcttt gtgattcgac ttagccatga gatgtaatgt caaataagca atttcttctt
    54661 cgggaaacga tacacctgcg attacctcaa tacgttgaac gatccgctgc gccacttgat
    54721 actctactcg cttagaaact tcttgttcga tgcctaattc cttgatttca aacccttctc
    54781 ggagccgttt gatccccaaa gccaagtgta aagtcagatt ctgtatgata aaatccgaaa
    54841 cttttaactt agcttctctt gtttcatcga gaatgataat gactagctct tcaaaactga
    54901 tgtctgggaa aaaacggctt tgccctaaat attctttcaa tgaatttcca taatggtttc
    54961 caaaaaaagt atccatgata aaatgccgtc gatttctttc ttccccttcg atccatgtcc
    55021 cttgaccatg cttagaaacg atttttagtg aatatggaat caatcgctcc ttgatttctt
    55081 gcatgtcctt tgtcaaactg gaacgactga tataaagctc ttctgccaaa tcatccataa
    55141 aaagaatggc atcttccaaa agcaattggt tcaatatata cttttgtcga tcttcggact
    55201 cataaaatcc ttgcggttct ctagcatatc caggtactat ttcttgccga ctcaaaaaca
    55261 agtcaaatgt cagtctttgt aaaatatgca gttggtagcc ataacctggt ttagcaatga
    55321 tcttacctcc gtttttttct actaactctt tgatccgctg caagtaatta cggattgtcc
    55381 gatcagataa taacaattca gaagctaaac gttgactggt gacatactcc ttcttgtgat
    55441 caatcaaata tctcaacagc aatttttcct tctgtttcat tatcatccac tcctattcca
    55501 tcatatgttc tcttcgatca cctctgctaa cttctggatg cctgtaggga ttgggacata
    55561 cgcttggaaa gggatactaa caacaggctt tccaacagat tctcctaatt ttttgaattt
    55621 atccaaaaac atcgtcgttt gcgggctgat cagaaataaa tcaaaatcac tattcttaat
    55681 catattatcg ccttctgtag ctgaaactgc atctacgagt acctcttctc ttttttgctt
    55741 aaagaaatcc gttgtctttg aggccatcat cgaggatgac attcctgccg cacaaataat
    55801 caatgctttt ttcataaatc aatcactcct tttattttta taaaccaagc atatcttgta
    55861 agcgttttct attcaaaata tatatttccg tagcattgcg gaaaaaatgt gtatcatatc
    55921 ttgaataata atttctggca ccgtgatata ctagtgatag aattttttca ggaggggatt
    55981 tagtgagtat cacagtgaat attttgtata caagtacaaa tggacaagcc agaaaatttg
    56041 cagaagaaat ggtcgaaaga aacattgtca aagcgattcg tgcagaagaa ggaaacgaga
    56101 aatatgacta ttactttcca ctagaagatc cagaatctct tttactgatc gaccgttgga
    56161 aagatgaaga agcaatcgaa aagcatcaca aatccgaaat gatggctcaa ataaacgaac
    56221 tccgtaaaaa gtataaatta aaaatgaaag tcgaacgttt cactgattta ccgtaaaaag
    56281 atacacatgg aatgatagca atttatcatc catgtgtatc ttcacttttt ccttattttt
    56341 tattcgatct catctaatga ttcaaaccgt gtttttctct tatttttcgg ataagtattt
    56401 cagtcacccc aatatacatg attcctaaac ataccccaag gatattctca aaaatgcgga
    56461 tcgttactgc tcctggaacc ccgaataaac tggcagtgat tgccaaagca ccaaaagaat
    56521 taaaaactgt tttatatcta taggtagaac aaacacctaa agctagacca cctaatatac
    56581 cgacccagtt aaaaggaata aattggctga taccaataaa taaaacacat ccaatcaatg
    56641 agccaatgat tcggtctact gctcgttctt tgaaaccaat cgacatcaat ccatagctag
    56701 atacaataga agaaaatgca aaccctgccc acatcaatcg ctgaaaaggg acatactctc
    56761 ctgcaacgat caaaagacta atgccaaatg catagatgag catccaaatt ttttcctgcg
    56821 aatacatgcc tttcaaaaaa atctctttaa acaagctttt gtctttgttc ttttctcgat
    56881 gttttctgta aaggagaact gaaaaccaac aaaaaaacaa aaataataag ctacttgttt
    56941 gtgtaaagaa attcttgttc aacgaatctt taggtaacga ataaacaata aagagatatg
    57001 aaaagccgta caaagaagca ttccccattt tgggatcact agcggttgcc attaatatgc
    57061 tgcttagtaa aataaaatga atcaacatgc ccataactga ccatttgatc agctggacat
    57121 acggtgctac taatagtgag aacatgacga ttgctaaacc tatgatcgaa tgggaaatct
    57181 tataaccaaa gtcaacaaaa cgaatactca tcaacataca gaataaaacc acagcgtatg
    57241 gtttatgctt cgattcaaat aatgttgtaa ttataatgat aaaacaaatg gcaaacaata
    57301 cgatgaataa tgatcgtaaa aacaatgaac aaatatacat gcacttttct tttttagaag
    57361 ctgcttctcg tattttttgt tttaaaataa acggatctag ttgtagagac tgataaaaat
    57421 ccacctgttg tcgtcctttc tttttacttt tattttttac agtcatctat gacaggttgt
    57481 aaatactatg gaacatcata tggcgttgtc attttcttgt caactatttt tcctattcat
    57541 gtttttataa aaaaacatat cgttttcttg tatgattaaa tcaccacaaa ataaacaact
    57601 gagagaacga tatgctttat gaatggttct atcaaaaaaa ttctgagatc aatagacaaa
    57661 aatttgatga ttacagaggt ctcttacgaa accttacaga agaaaaaaac attgatcgtt
    57721 gctgcagttc tcttccctgc tccatgtgtc tgtagaaatt gtggttctgc tgtggtagat
    57781 ggaaatagga aattaatggt ggtgaaaaac aagaagaagg aaaccattgt ccactttgaa
    57841 taatataatc atatgccaat ggttatacgc ctaaaaaagc agcgctatac ctgtaaaaac
    57901 tgtcgaagcc attggaacgc tcaaagttat tttatccgtc caaggcactc gatttcaaat
    57961 catgtcagac ataaaatcac ttctttactg actgaaaaag tgtcgttatt ttttatttcg
    58021 aaaagttgtt aggtatcttt gacaaccgtt attcgcacat tgaaagagtt gagaagctat
    58081 ttaccaaagt cttccaaaag aattctgtct tgagtgttga gggttgtgaa tttcgttctc
    58141 acgtttccgt tgaggataaa ctgagtttta tttccgcgga tggcgagaca gaaaaattaa
    58201 tcgagaaaat ttacctacac aaaaaattcc tcgattaaca aactatttcc ttagctgcac
    58261 taatcctaaa gaaatagaat tcttagttac agacatgaac gccacctact ttcagctcac
    58321 caaacatgtt ctaccaaatg cgaaattggt gattgatcga ttacttggtt tttccacgcc
    58381 tttcaaggag gcgtaacctt tattcacgag ttggttgaag ctttccgaga caaaagaccc
    58441 gacttgtttt tctccttatt gacaaagagc cattaaaact agagaaaaaa ttacaactga
    58501 tcgctgatta tttgtagaaa gaaaatcaaa gtattaccca ataaacttga gtcattaggc
    58561 aaaaaacact gcgaaactca agaatgattt tcgcagtgtt tttgtatatt ttttattaac
    58621 tagtattact acaaaggttt atttttcact tctcaacgca gcacaaaatt gtctttactt
    58681 atttactggt tgggttcaac cttctctact ccgatactaa tatttgtttg tatacccctt
    58741 ctaaaatcgg tagtttccat tcaattgatg ggtactagtt gattttaaaa actatgctta
    58801 ttcaattttt tattttagct catatatttc gtttctttct aaattttata ctgatgaaaa
    58861 caagtagcac acccaatatt gacaatataa actggctaat gatggtttct ccagtttttg
    58921 gaagatgctt atttccactg cttgttggat tgtttcctct tatatctgag ctatcagcaa
    58981 cttttctatt ctcttttgtt aaaaagatcg ccacttcttg ttctttttcg atcttgaaag
    59041 ttactggtgt cgcatc
//
LOCUS       DAFENC010000014        55809 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.014, whole genome shotgun sequence.
ACCESSION   DAFENC010000014
VERSION     DAFENC010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 55809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55809
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.014"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            139..996
                     /locus_tag="LP493_001135"
     CDS             139..996
                     /locus_tag="LP493_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HBL2133297.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            1111..2031
                     /gene="pstC"
                     /locus_tag="LP493_001136"
     CDS             1111..2031
                     /gene="pstC"
                     /locus_tag="LP493_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HBL2133298.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            2031..2915
                     /gene="pstA"
                     /locus_tag="LP493_001137"
     CDS             2031..2915
                     /gene="pstA"
                     /locus_tag="LP493_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBL2133299.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            2930..3736
                     /gene="pstB"
                     /locus_tag="LP493_001138"
     CDS             2930..3736
                     /gene="pstB"
                     /locus_tag="LP493_001138"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBL2133300.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            3752..4510
                     /locus_tag="LP493_001139"
     CDS             3752..4510
                     /locus_tag="LP493_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBL2133301.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGINLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            4523..5200
                     /gene="phoU"
                     /locus_tag="LP493_001140"
     CDS             4523..5200
                     /gene="phoU"
                     /locus_tag="LP493_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBL2133302.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            5438..5737
                     /locus_tag="LP493_001141"
     CDS             5438..5737
                     /locus_tag="LP493_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133303.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGRLMNTDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKK"
     gene            5763..6470
                     /locus_tag="LP493_001142"
     CDS             5763..6470
                     /locus_tag="LP493_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBL2133304.1"
                     /translation="MSIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLL
                     NISILFVVIGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYE
                     ELNYLTRPYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQV
                     GRDVIGSMTNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVL
                     SIPISVLFFLTVRRLKR"
     gene            6467..7234
                     /locus_tag="LP493_001143"
     CDS             6467..7234
                     /locus_tag="LP493_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBL2133305.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            7334..8902
                     /gene="liaX"
                     /locus_tag="LP493_001144"
     CDS             7334..8902
                     /gene="liaX"
                     /locus_tag="LP493_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HBL2133306.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEITQVQL
                     STTTGSIYLKDTDK"
     gene            9199..9519
                     /locus_tag="LP493_001145"
     CDS             9199..9519
                     /locus_tag="LP493_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HBL2133307.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            9519..9869
                     /locus_tag="LP493_001146"
     CDS             9519..9869
                     /locus_tag="LP493_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBL2133308.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            10036..10974
                     /locus_tag="LP493_001147"
     CDS             10036..10974
                     /locus_tag="LP493_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HBL2133309.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            10989..11819
                     /locus_tag="LP493_001148"
     CDS             10989..11819
                     /locus_tag="LP493_001148"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBL2133310.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            11863..12888
                     /locus_tag="LP493_001149"
     CDS             11863..12888
                     /locus_tag="LP493_001149"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBL2133311.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQIMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            12903..13841
                     /gene="galU"
                     /locus_tag="LP493_001150"
     CDS             12903..13841
                     /gene="galU"
                     /locus_tag="LP493_001150"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBL2133312.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKKLEAEGSKIDHNPKGITEIKEEKKK"
     gene            13966..14406
                     /locus_tag="LP493_001151"
     CDS             13966..14406
                     /locus_tag="LP493_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HBL2133313.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            14409..15011
                     /locus_tag="LP493_001152"
     CDS             14409..15011
                     /locus_tag="LP493_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBL2133314.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDTKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(15079..16185)
                     /locus_tag="LP493_001153"
     CDS             complement(15079..16185)
                     /locus_tag="LP493_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBL2133315.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILSGTDSYTDLASIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            16395..17396
                     /gene="ccpA"
                     /locus_tag="LP493_001154"
     CDS             16395..17396
                     /gene="ccpA"
                     /locus_tag="LP493_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HBL2133316.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(17732..20077)
                     /locus_tag="LP493_001155"
     CDS             complement(17732..20077)
                     /locus_tag="LP493_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBL2133317.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            20356..21258
                     /locus_tag="LP493_001156"
     CDS             20356..21258
                     /locus_tag="LP493_001156"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HBL2133318.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQIFDPEVFPELLAEEVIL"
     gene            21471..23246
                     /locus_tag="LP493_001157"
     CDS             21471..23246
                     /locus_tag="LP493_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HBL2133319.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSFYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYSSSKKMLPWFLGLAVSFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEAKKLKERPFLLSKQEWLKLSLFLLPLVGFSIVYQWIEYKNETTYSIAAIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALDASPTFHAVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYQKGT
                     IKKKKEFYLMGSGDGKTMNDLPIVFAFLKSGYAYAWRYKDFHQGGNYSFGTQEQVEQA
                     QELLNLPLMDNWIDSSDPRTPDFQLTKTAKVANVMIKIYQVLAIPVLIASIAGILLMI
                     LGTAFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            23503..24720
                     /locus_tag="LP493_001158"
     CDS             23503..24720
                     /locus_tag="LP493_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBL2133320.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEENTLCSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFLNRLTPYALILIRLFPHPDFVLASTRTKIKNKLINETRKKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQKEALATQMIKKAEGSPCFLLYQTFP
                     GIGALTAALLLGELGDITRFKTHKQLNAFVGIDIRRYHSGKYTGQDRINKRGNPKARK
                     IIFFTIRNMIRQQRAAPNHIVDYYYKLKKQPIPKKDKVATVACMNKLLKCMHAMVRAH
                     TEYDYAYAVSVDH"
     gene            complement(25167..26753)
                     /locus_tag="LP493_001159"
     CDS             complement(25167..26753)
                     /locus_tag="LP493_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HBL2133321.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFVVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADQIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETIEEIE"
     gene            27004..27228
                     /locus_tag="LP493_001160"
     CDS             27004..27228
                     /locus_tag="LP493_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HBL2133322.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            27370..29121
                     /locus_tag="LP493_001161"
     CDS             27370..29121
                     /locus_tag="LP493_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2133323.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLAPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAALLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGCSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQKLEAKIEGGEA"
     gene            29121..30905
                     /locus_tag="LP493_001162"
     CDS             29121..30905
                     /locus_tag="LP493_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2133324.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPTITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLTKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            31363..32214
                     /locus_tag="LP493_001163"
     CDS             31363..32214
                     /locus_tag="LP493_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL2133325.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELYQVIQKKYKDTFGCVEKIADFLAEIFNYQMSTDEKMYLTIHIARL
                     VHENRCK"
     gene            32311..34197
                     /locus_tag="LP493_001164"
     CDS             32311..34197
                     /locus_tag="LP493_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL2133326.1"
                     /translation="MGKYQELASKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGVVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTALLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPAFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNPGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEAGETDDRQKRSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSEAGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEEEGYSLETPVIVTNYTDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(34238..35140)
                     /locus_tag="LP493_001165"
     CDS             complement(34238..35140)
                     /locus_tag="LP493_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL2133327.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            35370..36773
                     /locus_tag="LP493_001166"
     CDS             35370..36773
                     /locus_tag="LP493_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBL2133328.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPTMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMNELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            36770..38206
                     /locus_tag="LP493_001167"
     CDS             36770..38206
                     /locus_tag="LP493_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBL2133329.1"
                     /translation="MMGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFP
                     VITGKKKMFEFDENHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGD
                     EKEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENL
                     CRVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASA
                     IATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPA
                     YALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFAS
                     VKNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDY
                     RIDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGN
                     GTLARSKKKSFNWYKKVIDSNGENLSND"
     gene            38351..39277
                     /gene="trxB"
                     /locus_tag="LP493_001168"
     CDS             38351..39277
                     /gene="trxB"
                     /locus_tag="LP493_001168"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBL2133330.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            39490..41217
                     /locus_tag="LP493_001169"
     CDS             39490..41217
                     /locus_tag="LP493_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBL2133331.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     TIIQKMTEE"
     gene            41233..41583
                     /locus_tag="LP493_001170"
     CDS             41233..41583
                     /locus_tag="LP493_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBL2133332.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKTKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAIIQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(41667..42527)
                     /locus_tag="LP493_001171"
     CDS             complement(41667..42527)
                     /locus_tag="LP493_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HBL2133333.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPSVEFNLFRRT
                     FVTDEKTLMQALQDALEEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            42619..43047
                     /locus_tag="LP493_001172"
     CDS             42619..43047
                     /locus_tag="LP493_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBL2133334.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            43209..43385
                     /locus_tag="LP493_001173"
     CDS             43209..43385
                     /locus_tag="LP493_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HBL2133335.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            43412..43858
                     /locus_tag="LP493_001174"
     CDS             43412..43858
                     /locus_tag="LP493_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HBL2133336.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(44014..45393)
                     /gene="brnQ"
                     /locus_tag="LP493_001175"
     CDS             complement(44014..45393)
                     /gene="brnQ"
                     /locus_tag="LP493_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBL2133337.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            46099..47070
                     /locus_tag="LP493_001176"
     CDS             46099..47070
                     /locus_tag="LP493_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBL2133338.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            47094..49286
                     /locus_tag="LP493_001177"
     CDS             47094..49286
                     /locus_tag="LP493_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HBL2133339.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNDKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            49303..49779
                     /gene="ybeY"
                     /locus_tag="LP493_001178"
     CDS             49303..49779
                     /gene="ybeY"
                     /locus_tag="LP493_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HBL2133340.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            49763..50158
                     /locus_tag="LP493_001179"
     CDS             49763..50158
                     /locus_tag="LP493_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HBL2133341.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            50173..51072
                     /gene="era"
                     /locus_tag="LP493_001180"
     CDS             50173..51072
                     /gene="era"
                     /locus_tag="LP493_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HBL2133342.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            51215..52027
                     /gene="recO"
                     /locus_tag="LP493_001181"
     CDS             51215..52027
                     /gene="recO"
                     /locus_tag="LP493_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBL2133343.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKSGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            52411..53328
                     /gene="glyQ"
                     /locus_tag="LP493_001182"
     CDS             52411..53328
                     /gene="glyQ"
                     /locus_tag="LP493_001182"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBL2133344.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENMKEAE"
     gene            53330..55405
                     /locus_tag="LP493_001183"
     CDS             53330..55405
                     /locus_tag="LP493_001183"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBL2133345.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGELPQSTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISD
                     VISKDTDRFGIGLSEGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKKSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
BASE COUNT        18082 a         9979 c        11845 g        15903 t
ORIGIN      
        1 atagcataga aacttttaat gagatagttt tttttacaat tatgagaatt tattttgtta
       61 tttaatgatt ttgattcgtt ttcatcaagt aatgaaaatg ataaaataaa catactttag
      121 gattaaagga gatttctaat gaaaaaactt aaattattct taccaataat aggattagcc
      181 attcttttat caggctgttc aaagtggatt gatcgaggag aatccattac ggctgttggc
      241 tcttctgctt tacagccttt agtagaaaca gttgctgaaa cttaccagac agaaaatcct
      301 ggaaaattca tcaatgtaca agggggcgga agcggaactg gtttgtctca agtacagtca
      361 ggagcagtcg acatcggaaa ctctgatttg tttgcggaag aaaaatcggg gatcgatgcc
      421 tcagcattag tcgatcatcg agtagcagtt gttgggatca ctcctattgt gaacaaggat
      481 attggcgtaa aagacatcag tatggaaaac ctgaaaaaac tatttacagg cgagatcaaa
      541 aactggagtg aagtcggtgg aaaagatcag ccagtagtta tattgaaccg cgcttcagga
      601 agcggaaccc gtagcacgtt tgaaaaatgg gtattggacg gagaaacagc tgttcaggca
      661 caagaacaag attcaagcgg aatggtgcgc cagatcgttg ccgacacacc cggtgcaatc
      721 agctatgttg ctttttctta tgtttccgat gatgtagata cgttgaatgt taacggtgta
      781 gaaccgacag atgaaaatgt gacaacgaac aaatggacga tttgggcata tgagcatatg
      841 tacacaagag atcatccaaa aaaactgaca aaagaatttt tagactatat cttatctgat
      901 gaagtacaag ataacatcgt tggagaacta ggttatatcc ctgtttctca tatgaaagtc
      961 gaacgtgatt ggcaaggaaa tatcgttaaa gagtaatctt tacacaaaat ttacaaactt
     1021 agctaaactt ttacatgtta ttaaaaccaa attgatgttc aatttgtaca ctgagtgagt
     1081 atgttaaacc tgattaaggg ggagtcatct gtggaagatg tgaaaaaagt attattaaca
     1141 aaatcaaaac gttcaaaaat ggaacagcgt ggaaaattca tcagtttttt atgtatcgcg
     1201 ctgatcgtgt tggttgtatt atctattttt tattttgtag ctagtaaagg attggccacc
     1261 ttttttactg ataagatcaa tgtatttgat tttctgtttg gtacagattg gaatccaagc
     1321 caaatcggag caaatgggaa accaatggta ggggcattgc ctatgatcac aggttcgttt
     1381 attgtgacct ttttatctgc tatcgttgcc acgccatttg ccattggtgc agcagtattc
     1441 atgacggaga tctctcctaa aaacggaacg aagatcttac agccggtcat cgagctgctt
     1501 gtaggtattc cttctgtcgt ttatggtttt atcggtttat cagttatcgt gccttttgtc
     1561 agaagtattt ttggcgggac agggtttggt atcttagctg gtacatttgt gttgttcgtt
     1621 atgatcttgc cgactgtcac aacgatgact gttgatgcat taaaggcagt gccacggcac
     1681 tatcgggaag cttcattagc gcttggtgcc acaagatggc aaacaatcta caaagtcgtg
     1741 ctacgagcag ccgtgcccgg gattttaaca gcagtcgttt ttggtatggc tcgtgcgttt
     1801 ggtgaagcct tagctatcca aatggtcatc ggtaatgcag cattgatgcc aacaggactt
     1861 actactcctg cttctacatt gacgtccatc ttaacaatgg gaatcggaaa tacaatcatg
     1921 ggaacagttg aaaataatgt gttatggtca ttagcgctga tcttgctatt gatgtcatta
     1981 ttctttaata tcgtgatccg tatgattggg aagaaaggag agctgaaata atgaacgcaa
     2041 aacgctcaga taaaattgct acaggtgttt tatatatagt ttcggggatc atcgtattga
     2101 ttttagcagc tttactactt tatatcttag ttcggggaat accgcatatt tcatggtcct
     2161 tcttgaccga accttccaaa gcctaccaag aaggcggtgg aatcgggatc cagctattta
     2221 actcgattta tttgcttttg atcacgatga tcatcagttt tcctatttct ttaggtgcgg
     2281 gtatctatct ttcagaatat gctggaaaaa actggctaac agatgtgatt cgcacgtcga
     2341 ttgaaatctt gagctcgttg ccttctgtcg ttgtcggttt attcggtttc ttggttttcg
     2401 ttattcaatt ccagtatggt ttctcgatta tttctggtgc attggctttg actgtattca
     2461 acttgcctct tttgactaga acagttgagg agtctttaca agcggtccat tacacacaac
     2521 gagaagcagg attggcctta ggtttgtcac gctgggaaac agtgataaaa gtggtggttc
     2581 cagaagcgac accagggatt ttgactggtg tgatcctaag ttctggaaga atttttggtg
     2641 aagcagctgc attgatctat acggctggac aaagtgcacc tgcgttagat tttacgaact
     2701 ggaatccatt aagtgtttca agcccgatca gcattttccg tcaagctgaa acattagctg
     2761 tccatatttg gaagatcaat acagaaggca cgatgcctga tggtgtttct gtttcggctg
     2821 gcgcttctgc cgtgttgatc attgctgttt tactgttcaa cttcggcgct cgtgcgattg
     2881 gcaaacgatt ataccgaaaa atgacttcag cctaaggaga agaagcaaaa tgaaaaaata
     2941 taactggaat gaaacaaatg tcatcaccat gccaaaagag aaagaagtag cactatatac
     3001 ggatgatcta catgtctggt atggcgacaa tgaagcaatc aaaggagtgg atctggaatt
     3061 tgaaaaaaat aagatcactg cactgattgg tccttccggc tgcggaaaat ctacgtatct
     3121 tcgttcgttg aatcgaatga atgatgggat cgctaatacg aaaatcactg ggaaaatcat
     3181 gtatcaaggc gtagatatta atgcgcctca agtggatgtt tatgagatgc gcaaacggat
     3241 tggcatggtt tttcaacgtc ctaatccgtt cagcaagtcg atttatgaca atattacatt
     3301 tgctttgaaa cagcacggcg aaaaaaacaa aaagaaatta gatgaaatcg ttgaaacaag
     3361 cttgaaacaa gctgccttgt gggaccaagt aaaagacagc ttggacaaaa gtgccttggc
     3421 tttatctggc gggcaacagc aacgtttatg tattgctcgt gcgatcgcga tgaaacctga
     3481 tatcttgctg ctagacgagc cggcaagtgc tttggaccct atttcgacag gaacggttga
     3541 agaaacactt gtaaacttga aagaagacta tacgatcatc atcgtgacgc ataacatgca
     3601 acaagcagct cgtatcagcg actatactgc ctttttctat ctaggaaaag taatggaata
     3661 tgacaaaact aacaagatat ttaccagacc aaaaattcag gcaaccgaag attatgtgtc
     3721 cggtcatttt ggttaagacg gaggcctcaa catgacaaaa gaaattattt catctaaaga
     3781 tcttcatctg tattatggaa agaaagaagc actaaaaggg atcaatctaa gtttcaatca
     3841 aggggaaatc actgcgatga tcggtccttc tggttgcggg aaatccactt atctgcgttc
     3901 tttgaaccgg atgaatgacc tgattccgaa tgtaacgatc accggaagtg ttttatataa
     3961 agacaaagac atctatggtc caaaaacaga tgttgttgaa ctaagaaaag aaatcggcat
     4021 ggtattccag cagccaaacc catttccttt ttctatctat gaaaatgtca tctatggatt
     4081 gaaattaaaa ggggaaaaag ataaaaaagt ccttgatcaa gtagttgaag aaagcctgaa
     4141 ggcagcgtct gtttgggatg atgtgaaaga caaattgcat aaaagtgctt tatctttatc
     4201 cggtgggcag cagcagcgtg tatgtatcgc acgtgttttg gcagttaatc cggaaatcat
     4261 cttattggat gaaccaacaa gtgcgcttga tcctgtttct actgggaaaa tcgaaagtat
     4321 gctgttagaa ttaagagagc ggtatacgat gatcatcgtg acccataata tgtctcaagc
     4381 ttcacgtatt tcagataaga cggcattctt tttagatggt cacttgatcg aatacaacga
     4441 tacgaagaag atattcatga atccagaaaa acaagagaca gaagattata tttcaggtcg
     4501 atttggataa ggaggaaacg gaatgctacg tacacaattt gaagaagaat tgctgaatct
     4561 ccataatcag ttctacgaaa tggggatgat ggtgagcagc gccgtgcaca agtcagttcg
     4621 tgcatacatc aaacacgata aaatcttagc ccaagaagtt atcgaaaacg atataaatat
     4681 caataacatg gaaacacgct tggagaagaa aagttttgaa atgatcgcat tgcaacagcc
     4741 agttacaact gatttgcgta tgatcattac ggtcatgaaa gctagctcgg atttagaacg
     4801 tatggccgat catgcggtgt ctgttgctaa atccacgatt cgcgtaaaag ggcagacgag
     4861 aataccggaa atcgaaaaag agatctccga tatgtccgat tatgtgaaaa aaatggtgga
     4921 caacgtccta gttgcttatg tcaaaacaga cgaaaaagac gcacgtacga tcgccaatat
     4981 ggatcaaaga gtcaatgact atttcaatcg aatctataat gcaacaatca aaaatatgca
     5041 ggaaaatcct gagacagtca tcagtggaac agactacttg aatgttgcca gttatctaga
     5101 acggatcgga gactatgtga caaacatctg tgaatggatc gtctacttgg ctacagggaa
     5161 aatcactgag ttaaatacga accacaatga gattttctaa actgaagctg tgattatgcc
     5221 gtttgtttag gaaaagaggt tgtgaaatca gcggttgtga aaaagctgtt ctgcatcaag
     5281 taataagaac agtcaaacaa aaaatagctc ctcatatttt tcgtttggct ggacttatta
     5341 ccgcagatgc aagcttttga acaccgttta ttcgggaaag ggtttgtgac aaaacatgtc
     5401 acaaaccctt ttcatcattt catagaaagg ataaagaatg caaaaaaaaa ttagcatcat
     5461 cactatattt tttatttgtg tgcttacttc atgggttatt cagcatcaag ctgctttata
     5521 tgaagtacct gtcatcgaga tcgaaaaagt acgaataaaa gaggatcatc aattgattac
     5581 aggaagactg atgaacacgg atcaaaaagg agaatcgatt tatttatcgg ttccttatca
     5641 aaaaaatcaa atagaaacag caaatataaa agcgagacaa atgtatctag tccaaatgca
     5701 tggagatgaa tggcagctag tagcaaaaaa aaaatgatgg ctggcttttc ttcttcacaa
     5761 gtatctccat tggcgccatg ttgcttattg gcggaaaaca gggtctattt gctttaggaa
     5821 gtctcatcat caatatcgtt ttacttttac ttttgttgct catctttact aaaacagaag
     5881 ggatttctct attaaatata tctatcctgt tcgtcgttat agggatgatt attagcatat
     5941 tggctttaga tggatggaat agaagcagta taatcaaaat ttcagctgca gttacgagtg
     6001 tttttttagc attttttatt tgtcttttga caatgaatca ttggaaagac caaggactgc
     6061 gctatgagga actgaattat ctgacacgac cgtatcgttc tgtttttctt tctagcgtac
     6121 tgattggaac agctggagga acactcgata ccgttatcac agtcattgcg acattagaag
     6181 aattgactaa gcgacaacca gaaataacag cgaaacagtt atggctttca ggaaggcaag
     6241 tgggtcgaga tgtgattggc tcgatgacca atatcctttt gttcgtctat atcagtgggt
     6301 cagttccatc gcttctttta tatttaggaa atcaatggtc gttcaaagaa acgatagaac
     6361 agcatttatc attggaattt ttacgcgtca ttgctggcag cttaggaata gtattatcga
     6421 tccctatctc ggtcctcttt tttctgactg taaggaggct gaaacgatga atgtacttat
     6481 tatacttgtt gggattttag caatcagcgt gctacttatt ggcggtacgc aaggtatgta
     6541 tattctttta ggcttattca tcaatttagg gatctttttc ctgttgttat tcggttatca
     6601 tcagaagtgg ccgatactgg cattgtcggt cataggattt ttattgattg ctgtggttat
     6661 cttatttttt atcaacggtt ataatctaaa aatgcgtgca gcttttgtga gtatactgat
     6721 ctttttattt tgtttcctac tattgcttcc tatcactgat tttttagcga tccaaggttt
     6781 tacatcggta gaactagaag aattatctgg cttagataag actttagcga ttgattttag
     6841 attacttacg agatcgttgc ttctgattag tcttagtggt gctgttttag atgctagtgt
     6901 agcaatttct agtgggacat tcgaagtata tcaggcaaat ccgcaattat ctttttacca
     6961 attgcgccat tctagtttcg ctattgctaa aaaaatattg gcgtcaacag taatgacact
     7021 tctttttgca ttcatgggaa gttctttagc gttgatcctc tggtttattg atttagacat
     7081 tccttttcag caagtgatca atgaaaaatc atttgttcta gaatatacga tggctattct
     7141 taccacattg tctgcactac ttgttcttcc tttaacctgc gtgactacag catatctctt
     7201 tacaaaaaag aaagaacaac tcaagatgga gtaaaagtta caacttaagt cctatgacat
     7261 ttttactgaa tcagtgcata atatggatgt aaggaaaagc ttgcaaacaa ttttgcttaa
     7321 ggaggcaatt tccatgaaag aaagagaacg tattttagat ttagtgaaaa aaggaatcct
     7381 ttcgactgaa gaaggcttag atttattaga aagcatggca actgaaaaag acgaaaagca
     7441 aataaaaaaa gaagcagaca aggtaactgc tagtcataaa gaaaaagatc aggcaagtca
     7501 attgatcgat aaacttgaaa acggcgaaga agaaatttct gagccagttg atccaaagga
     7561 aagagaaagg caagatcaag aaaacttaga aaagatctta gatgaactag caactgaagc
     7621 gaataaaact tcggcgcgtc tagatgaagt aaatgctcaa ttcgctgaca ataaggcagc
     7681 acgcaatgag aaacaggaag cattgatgca gctgaataca aaagaagaat taggcgagtt
     7741 gacagaagaa gaattagcac agcgtcagac gttagaagca gaaatcaaag aattagaagc
     7801 tagtggcgat acactgttag aagaacaatt gaaattagaa gcagaattaa aagatatccg
     7861 taagaatcaa tggtctgaga aaaaagaaac gtttactgat aagtttgaat tgccagatga
     7921 ttggaaagat caagcaacag atacactgaa tcaagtaggc gaaaaaatgt cagaagctgg
     7981 atcacagtta ggcaaattct tgaagaaaac attccaaact gtttcagaaa cagtgaatga
     8041 caacatggaa tggaaagatg tcagcttacg tgtccctggg attgcgacaa cgaaatttga
     8101 gcatgaattt tactatgaag ctcctgcagc aagtatcctt gatatcaagg cagcaaacgg
     8161 aaacgtgacg ttaaaaacgt gggacagcaa cgatgtgaaa gttgaagcta agatcaaact
     8221 ttacggaaaa atgggtgctg aaccatttga agcattctct gaacggagcc agattgaggt
     8281 taatgaagat catatctcct tccaaattcc aaataaacgt gtgcgtgcag accttgtttt
     8341 ctacttacct aaacgagtat acgaccacgc agctattaaa cttctaaatg gcaacatcat
     8401 gattgaaaca ttggaagcta aagatattta tacaaaatct acgaatggta acatcatcgt
     8461 ggaccaatta actgcaacga tgctggaagt agaaggtgta aacggcaata tcgatattcg
     8521 aaacgggaac atcttagatt ctattatcga aacagtaaat ggtacagtga catttggtgc
     8581 gacagcagaa aacctttctg tgtctttggt aaatggtgat gtacgtctta cgattaaaga
     8641 agataatttg aaaaaagtag aagcaagttc agtgaacgga aatgtcaaag tcgctttacc
     8701 agatggcatc ggtttggaag gacatgctaa aacaagtctt ggaagtatca acagccgtct
     8761 gtccaattac gaagtagttc gtgagaaaaa agaacggaca aaccaaatgt tgcaattccg
     8821 tcgtgtttca gatggtgaaa tcacgcaagt gcaactttca acgacaacag gaagtatcta
     8881 tttaaaagat acagataaat aaagaggttg tgaaagagat gttcagcctt gagcaataag
     8941 aagcgatttt gtaaaatagc ttcccctatt ttacaaaatt gtgccttatt gccgataggc
     9001 tatctcttga acaccgttta ccaagagatt atgaacctgc caattatcgc cgagtcacaa
     9061 ggaataattt cagaaaaagc tcgtcacgtt ttatgaatat ggtaatttgt gaccgagaat
     9121 tttgcagaaa gacaccgatt aagaagaagg ttgtcacaac gattttcttc atttaaaata
     9181 gtagaacaga ggtgagacat gatgaaaaaa aagttgacaa aatccaataa aaatgttgtt
     9241 ttgacaggga ctttagcagg aataggagaa tacatcggga ttgatccgac tgttatccgt
     9301 gtgctttatg tattcctgag cttagttgct tttggaagtc caatcatttt atacatttta
     9361 ttagctttga ttatcccatc tgcgcgttct gcacgaacaa actatggaca taacaatgca
     9421 tattatgaaa aaaacaatta tcgtgaacaa actcgtgaac aaacaaaaaa acgcaaagaa
     9481 gcggaaaaaa tcgatgatga cgaatggagt gacttttaat gtcgtacttt caacgtattt
     9541 tagttaatac gttaacattc atatcattgg ctgttctttt tcctgcgatg gtccatgtga
     9601 gcagtatttg gacggccgtt cttgccagct tcgtattgtc tgtgttgaat atgtttgtca
     9661 aaccgatttt gacgatactg tccctgccct ttacattagt cacattggga ttgtttacgt
     9721 ttgttatcaa tgcagcgatt cttaaaatga cctccttttt tgtgggagca gaacatttta
     9781 gtttttcttc attcggtgca gcgttgttag tagctatctt gatgtcgctt gtcaatgtaa
     9841 ttgtcagtga acataacagt agaaaataaa agaaagctgt gccgaactat cggcgcagtt
     9901 tttttattta gaatcaggaa tgcgttttct attacattgg taattaaata aaaacgtttt
     9961 ttttaattgg tagtactttt ggctagacaa tgataaaatg atagagaaca ctctaataga
    10021 aatgaggtag catgaatgtc agaagttgta aaagttagcc aattagtgaa aaaattatct
    10081 ttggaaatcg tgacaggcga cgagaaaagc ttagaccgtg tcatcgtaac tggggacatc
    10141 tcacgcccag gactagagtt gactggttat tttaattatt attcccataa tcgtttacag
    10201 ctatttggca gtaaagaaat cagttttgcg gaacggatga tcccagaaga gcgtttgatc
    10261 atcatgagaa gattatgtag tgaagatatg cccgcattta ttatttcaag aggattaccg
    10321 gctccagaag aaatgatcca ggcagcaaat gaaaatggga tagctgtact gcgttctccc
    10381 atctcaactt ctcgtttatt aggagaatta tccagttatt tagatggtcg ccttgcccct
    10441 cgaacaagtg tccacggtgt tttagtggat gtttacggat taggtgtact gattcaaggt
    10501 gacagtggga taggaaaaag tgaaacagcg ttggagttga tcaaacgcgg tcatcgattg
    10561 atcgcagacg atcgagtaga tgtttatcag caagatgaat taacggtgat cggagaaccg
    10621 cctaaaatcc tggaacatct aattgaaatc cgaggaatcg ggatcattga tgtaatgaat
    10681 ctttttggtg cgagtgcggt acgtggctct atgcaagtcc agttggctgt ttatctggaa
    10741 gcatgggcaa aagataagaa atacgaccgt ctgggctctg aagacacgac cgttgaaatc
    10801 gcggaagtgg gcattccaca aataaaaatc cctgtcaaaa caggacgaaa cgttgcaatc
    10861 atcattgaag tagccgcgat gaatttccgt gcacgtacaa tgggctttga cgcaacgaaa
    10921 acatttgaag aaagattaag tcgcttgatt gaagaaaact caggcaacga ctagcaagga
    10981 gtgacaatat gttagcacaa atcaatcgag ttgcttttga gcttgtaggg attcctatct
    11041 actggtatgc attgatcatc gtatcaggta tcattatcgc catgtggctt agcagcagag
    11101 aggctgttcg ggtaggatta aaagcagatg atgtgacaga ttttatgttg tggggattgc
    11161 ctatctccat tattggtgct cgcttatatt atgttttatt tgatcttccc cagtatatag
    11221 ctgatccaat ccaaatattc aatatccgtt caggaggctt agctatttat ggcggactga
    11281 ttgcaggcgc gatcacgctg tattttttta ctaaatatca ttttatttct ttgtggactt
    11341 ttttagatat cgctgcacca agtgtattat tagcacaggc aatcggtcgt tggggaaatt
    11401 tcatgaacca cgaagcatat ggaccagaca cgacgcgaag cttcttagaa agtctgcatt
    11461 taccgcaatt catcattgat aatatgtata tcgaagggat ctatcgtcaa ccaacatttc
    11521 tttatgaatc actttggagt ttgattggat ttattttgct tttgttttta cgaaagaaac
    11581 cacacctttt gaaaaaaggc gaagtccttt tatgttatct aatgtggtat agtttcgggc
    11641 gtttctttat tgaaggatta cgtacagaca gtctttactt tttaggtgtg atccgtattt
    11701 ctcaattatt atctgctgtg ttatttgtcg gtacattgat tctatttatt tggcgcagaa
    11761 aaaaaggaaa tttaccggat tatgaccgct cattaggaaa aaatcaacaa attatctgat
    11821 ttttagagcg ttaaaaatga aaaaaatttc aggagtggta aaatgaatta tagagtagcg
    11881 gttttaggac caggctcttg gggtactgct ttggcacaag tcctcgccga aaacggacat
    11941 gacgttcgga tttggggaca tcgtgcttca caagtagaag aaatcaacac ccaacacacg
    12001 aatcaacgtt atttaccaga tcattatcta cccgattcca tccaagcatt caccaatatg
    12061 gaagatgcag taaaagacgc agatgcggtg ctattcgtca ttccaacgaa agcaatacgt
    12121 tctgttgcaa aagaactagt gcctaaattg aatacaaagc cagtgatcat ccatgcaagt
    12181 aaaggattag aacagggaac acataaaagg atctctgaca tcttgttaga ggaaatccca
    12241 gcagaaaaaa gaaaagctgt tgttgttctt tctggaccaa gccatgcaga agaagtagcg
    12301 aaacatgaca tcactacgat cacagctgca agtacagatg caaaagcagc aaaatatgta
    12361 caagagctgt tcatgaataa ttattttcgg atctatacca atcctgatgt gatcggtgta
    12421 gagatggggg cagctttgaa aaatattatt gctattggtg ctggcgctat tcacggctta
    12481 gggtttggcg ataatgcaaa ggcagcaatc atgacgcgcg gattagctga gatcagccgt
    12541 ttaggtgtag caatgggtgc aaacccgctg acctttatcg gattaagcgg agtaggcgat
    12601 ctagtcgtta cttgcacaag tgttcattct aggaactggc gcgcaggcaa cttgttagga
    12661 caagggcagc ccctagaaga ggtgctagcc aatatgggaa tggtcgttga aggtgtgaat
    12721 actactcaag cagcgatgga actagcccaa ataatggaaa tcgaaatgcc catcactcaa
    12781 acaatctatg aagtgctgta tgaacaaaaa gaaatcaaaa cagccgcaaa agaaatcatg
    12841 ttacgtgatg ggaaaaaaga aaatgaattc tcattaacaa ttttttgaag gagcgaatgt
    12901 atatgaaagt caaaaaagca gttattccag cggcaggatt aggaacaaga tttttaccag
    12961 caacaaaagc tatggcaaag gaaatgttgc caattgttga taaaccaaca atccagttca
    13021 tcgttgaaga agcgttgaaa tcaggaatcg aagacatctt gatcgttaca ggaaaagcta
    13081 aacgaccaat cgaagatcac tttgattcaa atattgaatt agaaacaaac ctaagtgaaa
    13141 aaggaaagac cgaattattg aaattagtag aagaaacgac agatgtcaac ttgcatttca
    13201 tccgtcaatc tcatccaaag ggtttaggac atgccgttct tcaagcaaga gcctttattg
    13261 gaaatgaacc gtttgtcgtt atgctaggcg atgatatcat ggaagatgaa gtaccattga
    13321 cacagcaatt aatcgatgat tacgaacgta ctcatgcttc tacgatcgcc gttatgcaag
    13381 ttcctcatga tgaaacttca aaatacggaa ttatcaatcc aggagaagta ttggaagatg
    13441 ggttatacaa tgtcaaaaac tttgttgaaa aaccagatcc aagcaaagca ccaagtgatt
    13501 tagctattat tggacgttac ttattgactc cagaaatttt tgatgtattg tccgagcaac
    13561 aaccaggagc cggaaatgaa atccaactaa ctgacgcaat cgatacattg aataaaacac
    13621 aacgcgtatt tgcccgtaaa ttcacaggta aacgttacga tgtcggtgac aaatttggtt
    13681 ttatgaaaac aagtattgaa tatggtctaa cacatccaga agtaggtgca cctttacgtg
    13741 agtatatcct gtctttaggt aaaaaattag aagcagaagg aagcaagatc gatcataatc
    13801 caaaaggaat aacagaaatc aaagaagaaa agaaaaaata accctttttt ctaacgagct
    13861 tcagctgcta attgaataaa aagtagttga agctcgtttt tatttgttta aaaaacacga
    13921 aaatgctatc cttatagaaa agagagacaa gaagggagtt tgatcatgtc aggaggagaa
    13981 attgcaggat tgatcgcagc aatcgccttt gcgatacttg tcgtttttat cgttcgtgtg
    14041 ttgttgcaag tttctaaaac tttagaaaaa gtagatcaga ctgtagcaga agcaaatacg
    14101 acgatcgaaa tcgtcacaaa agacgtagat cttttgtcta gacaagtaga aggcttgctg
    14161 gtcaaaagta atgaactgct cttggatatc aatggaaaag tcgcaacgat cgatccattg
    14221 ttcacagcag ttgctgattt aagtgaaagt gtatcagaac ttaatcattc tagtaaaaac
    14281 atcgcgacga aagtcggcgg aatcggtaaa acgacagcta aagcgacggt tgccggaaaa
    14341 gtcggtggga cagcgatgaa attttttaaa aacaaaaaac atactgaaac gacaggagga
    14401 aaataaaaat ggctaaaaaa ggtggatttt tattaggtgc agtagtcgga ggaacagccg
    14461 cagcaatcgc cgcgttattg ttagcaccaa aatctggtaa agaacttcgg gatgaattag
    14521 ctgcccaagc ggatgatttg atggatatgg cttcagatta cacagatatg gcgaaagaaa
    14581 aatcgactga gttaacaggt attgcaaaag aaaaagcgca agatctttct caacaagcag
    14641 gtgatctagc aggtagtgtc aaacaaaaag taagtgaatc agcagatgaa gcaggaagtg
    14701 aatctgacga tatcttgtta aatcttaaag aacaatcagc tgacttatct aatcgtttca
    14761 aaaaaacggc agaagatatg aaaaaacctg cagatgaatt aggaagtatt gctaaagata
    14821 cttcagaaga tatcatgatt gatgtaaaag acgctgctgg taaagcagga gatactgtca
    14881 atgaaggaat gtcagaagca aaaccagttg cagatgacac aaaagaaatg atgaaaatgg
    14941 caaaagaaga tgcgaaagaa gctaaaaaag aaataaaaga tacaatgaca gattcatcta
    15001 caaatcacta aaatcactaa aatcacaaat ttatagaata aaaaggtggg agcggactag
    15061 ctctcacctt ttttactctt atttttctaa aactagtaat tcttttggtg tagtcgtgaa
    15121 tggcacacag ccatcgcttg tcacatatac acagtcttcg atacgtaccc ctactttttc
    15181 aggaatatag attcctggtt caagagagaa gcacatccct tcttcgatta ctaagtcatt
    15241 tccttctaca agggaaggga attcgtggac ggttgttccg atcccgtgac ctaaacggtg
    15301 attgaaatat tcgccgtagc catagctgtt gatcacgttt cgtgcgattt gatcaagttc
    15361 acctgctgtc acacctggac ggacggcttc ttgtgcggca agctgtgctt caagagtgat
    15421 gttgtatatt ttttcttgga agtcggttgg tttttgataa gcaattgtac gagtagcatc
    15481 actgcaatag ccattccaaa caacgccaag atcgaataac acaagttcat tcggtgaaat
    15541 cttcgtgttt cctggtgtac catgagggct tgcagcattt gctcctgcaa ggactaatgt
    15601 gtcgaaagac atttgtgaaa caccttgttt tttcaattgg tattcgattt ctgcaatgat
    15661 cgcttgttca gtcacgcctt ctttcactgc tttaaagcca atctcaaatg caacatcggc
    15721 ccatttacca gcttcgatca gtttgtcttt ttcctctaga gttttgatca gttgtagacg
    15781 ttggatgatg gaagctagat cagtgtaaga atccgttccc gacaagatat cagagatagc
    15841 atcgaagcgc tcgacagtca aggcgttctt ttcaatccct acattgccag gctgaccata
    15901 gcgagcacga agttcttttc cgatgatctc ccaagggttt tcgctgtcta aatagccacg
    15961 gacatcatac gcccaactac tgttttgagc atcttcaact tccaaagcag gagtgaaaag
    16021 gaaaggatct tgttcaagag ggataaaaag agctagtaca cgctcatgag gatcactttc
    16081 gtatccggaa aagtaagcga tgtggccagg gtcgctgata taagccaatt cgacttggtg
    16141 ttgtgccatc cattgacgta gttcattgat ttttacgtta ttcatttggc aacctacttt
    16201 ctaaattaat tttgtattca ataattgtac cactgattta ttaaaagacc aacgttctaa
    16261 aaactgaaaa aagtaaaaat tttcatgaaa acagagataa aacggttgca attcttgaga
    16321 ttatttgata ttctatttta gaaatgtaag acgtattttc agaaaacata taaaatatga
    16381 ataggagaac acaaatggaa aagcaaacaa tcactatcta tgatgtagcg agagaggcaa
    16441 atgtttcgat ggctactgtt tcacgtgtcg taaatggcaa tccaaacgtc aaaccagcaa
    16501 caagaaaaaa agtcttggaa gttatcgatc gcttggatta tcgtccaaac gcagttgcgc
    16561 gtggcttggc aagtaagaaa acaacaacag ttggggtaat catccctgat gtcagcaata
    16621 tgttctttgc ttctttagca cgtggtatcg atgatgtggc aacaatgtac aaatacaata
    16681 ttatcttagc aaattcagat ggtaacgacc aaaaagaagt caatgtattg aataacttac
    16741 tggctaagca agtggacggc gtgatcttca tgggtcacca tatcacagac gaaatccgtg
    16801 gagaattttc acgttcaaaa actcctgttg tattagctgg ctctattgat ccagatgaac
    16861 aagtaggtag cgtaaacatt gattatgtat cagcaacaaa agatgcagta aacaaattgg
    16921 caaaaagcgg caataaaaaa atcgcttttg tcagtggtgc gttgatcgat cctatcaatg
    16981 gacaaaatcg tctgaaaggc tataaagaag cattaagcga aaataaccta ccatatagcg
    17041 aaggattgat ctttgaagca caatacaact tcaaagatgg tctatctcta gtcgatcgga
    17101 tccataatag cggtgcaaca gctgtctatg tttcagatga tgaattagcc atcggtattt
    17161 tggatggttt attagaccgt ggcgtgaaag taccggaaga attcgaaatc atcacaagta
    17221 acaattcact actgacagaa gtagctcgtc ctcgtttaac aagtatcaca caaccattat
    17281 acgatttagg ggcggtatct atgcgcctat tgacgaaaat gatgaataaa gaagaagtcg
    17341 aagaaaaaac gattatcttg ccttatggaa tcgaagaaaa aggatctaca aaataataaa
    17401 aggacaacca ttcagaggtt gtgagcctgc cgtttaactc tgcgttacaa ggagcaattt
    17461 caaaaaacag catttcatgt ttgatgaata ttgtgactcg tgattcggag ttggcaggag
    17521 aacaccgttt attcgggaaa aggggttatg acaaaatttt gtttaatcct ttttttttgt
    17581 cttaaaaaag agagaaagtg gttgaaatta catttatcgt atataaaaca atccgtgtat
    17641 agatgctgca ttatgttcac caccatcaaa aaaataaggg actgtgacaa tactattgtc
    17701 acagtccctt attactgtgt attctattaa atcaatcatc tttctcatct gattctttgg
    17761 ttgcttgatt cgctcttgca taagctgaag cggtgttcca gtaatctgta tagttttcat
    17821 cggtaccgcc aacgccaaat ttaaaggcgc ttttcttcgg tccatttttc gcccatagcg
    17881 attcaactgt ttttcctggt gtttggatgg attttttatt gacagtaact tttccaggtg
    17941 tttgaccagt aaatccagat acttttttct tcatcacatc agatgataat tcgaatttct
    18001 catcagtgcc aaaaatgtca ggttttgctt ggtaagcttg attgatcaga ttggcaagat
    18061 aattagccga acgtatcctt gctttgctgt ccattccagt attgtcatcg tgccctgccc
    18121 agctactgat ggtaatagac ggagtagaga caattagcca tgaatctcgg tattcattgg
    18181 tagaaccagt ttttccgacc caatctgctt ttcctagatt tccgtttaag cttgagatgg
    18241 catctttgaa tggtgtagtg atttttgcat tgatcacact gcgcatcatg tcattcatga
    18301 tcgatgccgt tgcttccgaa tagatccgga cagagttgct ttcgtgttta taaattacat
    18361 ttcctgcgtt atctgtgatg gaatcgatga tatagccttc ttcatagacg ccgccgtttg
    18421 ctaaagcctg aaatccattg gtctgttgaa gcgtcgtgac atctactgta cctaaaggag
    18481 cagattcaac gccccaattg tcatttgccg ggtagttcat ctttgccaag tagtgctcgt
    18541 aagcatattg tttcgatcca ccggaattca acacatcttg atataagtga taagccggga
    18601 tattgttgga ccattctagt gactcacgga cggtttggaa ggtgttcgat ccttcgttag
    18661 tagcattgac gattttctcg ccagcatttt ctccttcttg ccaagttgtt gcataatctg
    18721 atacacggga ttctgatccg ataagcccca tgtcgattgc aggtccataa acaagaactg
    18781 gtttgattga tgagccagct tgacgttctg tatcgaaggc atggttattt tgattctgac
    18841 tgtaattccg tccgccaacg aatccgtaga tgcggccagt tctgttatcc atcaatacat
    18901 ttccggtttc tacttgactg ccagcaccat catctaacat gtatccataa ttttctacgc
    18961 cattttgcaa tgcagcatag acatctttat cgattgtcga atggattgta tatcctttat
    19021 tttggatcgt ttgctgtgcc ttttgataat aagcgtcact gaccgatgaa tcagacatat
    19081 cagcgttgtc tttttcagcc aattgttgtg caatgattct tgttgcttca ttcatcacag
    19141 tataatacaa gaattctctg tcagtctgtt ctgcgatttg ttgtggtaga aagtcttttg
    19201 taaggtcata ggcttttgct tcttcgtatt gttctttcgt aatttggcct tcacgataca
    19261 tactgaataa aacaaaatct tttctggcaa ggccggcaga aagatcttct tttagcgcac
    19321 ctgtgttcgt gtatggacta tacgtgatcg ggctttgggg taatccagcg atataagcag
    19381 cttgcggcag cgtcacatct tttgcatcta caccaaagat tcctcttgca gcttcctgga
    19441 ctccagcaat gttttgtccc ttattattac gaccaaatgg tgagacattc aaatacgtag
    19501 caatgatctc atcttttgaa aagtattttt ctacttgtgc agaaagaatg atctcgtttg
    19561 ctttacgttt gaatgttgtt tcatctgtaa ggatctgctg tttgactaat tgctgtgtca
    19621 aagttgatcc accagaagag ccaataccag tagcttcaga tactaatgct cgtaaaacag
    19681 ctttaggaac gtaaccttgg tgtttatcga agtattcatc ctctgtgctg ataattgcag
    19741 ttttcaataa aggtgaaatt ttatcagatg aaatagtcgt gcgcatcaga tctgtctgga
    19801 tttttgatat ctctgtatta tctgcataaa caatctttga cgtttctgta atgtttccta
    19861 gttctgtctg cagtgctttt ttagtcggca attgtgtgtc ttcgacgaga taggcaaaat
    19921 agccagcgcc tattccaata cctagagctg cgaacatcaa aagaagaaca gtaataaaaa
    19981 cagtcaatga ttgaaaaact ctaaaaataa tcttaggaac aaaccatttt tctttttttc
    20041 ttctattctg tttttttcga gtatttttgc gtggcaaaag ggtcacctca actaatggtt
    20101 ttatttcgct aattatagca aataatagaa caaaaaaaca gacaaggctg tttttggcag
    20161 gaatttcttt tttaaaagag ttaaaacgtg agaaaatgat cttttttata aaagagttct
    20221 taagcttttc tttagagaaa atttcagtta ctatggagaa cagggcaaag aaaaatcaat
    20281 cattttcttt gtatatcatc ttaccaatat ataggaattg ttagtaacaa ttgcctttca
    20341 aggaggaatc catccatgtt attaggctca cacgtcagca tgagcggaaa gaaaatgctg
    20401 ttaggagcag cagaagaagc agccagttat ggatcttcga cttttatgat ctatacaggc
    20461 gcccctcaaa acactagaag aaaagccatc gaagagatga atattgatgc cggaaaagcg
    20521 tacatggcag aaaacggtct aacaaatatc gtcgttcatg ccccttatat cattaatttg
    20581 gggaatacga tcaaaccaga aatgtttcct tttgccgtcc aatttctgag agaagagatt
    20641 gttcgtgcgg aagctttagg cgctactcaa attacacttc acccaggtgc tcatgtaggg
    20701 gcaggaacag aagccggaat tgctagaatt attgaaggct tgaatgaagt tttgacaaaa
    20761 gaacagacgg cacaaatcgc tttggagaca atggcaggta aaggtacgga aatcggtcga
    20821 acatttgagg aattagcgca aatcatcgat ggagtaaaat tgaatgaaaa attatccgtt
    20881 acttttgaca cctgtcatac gaatgatgcc ggttataata ttaaagaaga cttttcaggt
    20941 gtaatggaag agtttgataa gatcatcggg ttagatcggc ttaaagtact ccatatcaat
    21001 gattctaaaa atccgcaagg ttcgcataaa gaccggcacg ccaatattgg ttttggaaca
    21061 atcggattcg acacgctgaa taagatcgtc catgatccaa tgtttgacaa tatttcgaaa
    21121 atcttggaaa ctccctatgt cggcaaagat aaaaagaaag cttacgcacc atatggaaaa
    21181 gaaatcgcca tgttcaaagc acaaatattc gatccagaag tgtttcctga gttattagca
    21241 gaagaagtga tactctaaga ttttctatct gacagcagca aaaaaggacc aggcacattg
    21301 ccttgtcctt ttttgtttaa gaaacaaagg agtgcttttt gcagtctttt tcatcatgca
    21361 tcttctcccc cctcttttta aatttagaca aacagggtat actggtagaa aagtaaaaaa
    21421 acgaaaagtt tcacaagcaa gtggcaaaac gtgattggaa ggacgaaaag atgctgaaca
    21481 ctttaaaacc cttgatcaac caactaaaaa agaaacatac atactttatt cttggcatag
    21541 ccctattatt tacaattatt cgtttgtatt tatatagtaa agcaatctat ggaacagaca
    21601 tgtcggcaac ctatgatgac cagctgctga ttcgctatgc tcaaaatatt ttggacggta
    21661 aatggctagg ggagtatacg actacaacac tttccaaagg aatctcctac agcttatttt
    21721 tagtacttgc acataaactg catctttctt atgcagtttt gttcggcatg ttcagtattt
    21781 ttgccagtat attggttgca ctcgcgttta aaccgatcgt gaagaacaag tatcttcttt
    21841 taagtttcta tttttatttt ttgttttctc cgattagttt tacacatgaa tattccactc
    21901 gaacgtatcg taatgccctc gtgattccgg ctgttgagat cattatcgct tgtttactag
    21961 ctatttatta ccgtaaatat agttccagca aaaaaatgct gccgtggttt ttagggctag
    22021 ctgtttcttt tcctttcttt tggttcattc gcgaagattc catctggctt cttcctttta
    22081 ctgtagtcgc gttaggcatc agtttcgtcc agatcttgct aggacaagac ttttctttca
    22141 aagaagcaaa gaagttaaaa gaacgaccat ttctcctttc gaaacaagaa tggctgaaac
    22201 tttcattgtt tttactccct ctagtcggtt tctccatcgt ctatcagtgg atcgaatata
    22261 aaaacgagac aacatatagt attgccgcca tcaatgaccg ttcgagtggc gaatttggac
    22321 gtttgatgaa acagctgatc cgaatagatg acgaaacgaa cttaaataaa gaaaacagtg
    22381 agatatgggt ctcgcatgct gcattaaata aagcattaga cgcatctcct acatttcatg
    22441 ctgtttctac tcgtattgac gaattgtata cgactcatgc gtggacccaa ggtggaaaag
    22501 taaaagaatt accaggagat atcatttttt gggcattgcg agatgtggta agcgaatctg
    22561 gttattacca aaacaatgca aaagaaacca atgatttttg gaaaaaagtc aatcaagaat
    22621 tagaagaagc ctatcaaaag ggaactatca aaaagaaaaa agaattctat ctgatgggat
    22681 caggggatgg aaagacgatg aatgatctgc caatcgtatt tgcttttctg aaatcaggat
    22741 atgcctatgc atggcgatac aaagatttcc atcaaggggg gaattatagt ttcggtacgc
    22801 aagaacaagt cgaacaggcc caagaattat tgaatcttcc actaatggat aattggatcg
    22861 atagcagtga tccgagaaca cctgatttcc agttgacaaa aacagcaaaa gtcgcgaatg
    22921 tcatgataaa aatttaccaa gttctggcca ttcccgtgct gattgcttca atagcaggga
    22981 tattacttat gatactagga accgcatttg caaaagctga tcgtgcctat tatagttcct
    23041 ctttgattgt agtcaccgga ttaatactga cacaattggt ttttcttttc ggcgtctcgt
    23101 ggttttgttc ttatgcgcca gaaaaaaagg attatttttt aagtgtctac actggcgcag
    23161 gcgtgccatt aacgcaattc atcgtagtaa caagcatgct agttttcagt aaattgaatc
    23221 tgaaaaaagc tttatcttcc aaataaaaac atactaagat tagaggagaa catcattgac
    23281 gaatgatgtt ctcctctatt ttctattttt agattatagt gaagagtgaa agaaagttcg
    23341 aacaaagcct tgaggactat gagtccctat caaaaaccga acttctttac tgtcatttta
    23401 gaatcaggtt tacgtatgtt ggggccatga gcccgtgtat aggaaattgg aatcgaaatg
    23461 aagcagtaaa gttctttcaa aacttaaaaa ggaggaaaac aaatgcctta cattcttgca
    23521 ttagatgttt caatgggaca cagctacagt gtcctataca aagacgacac ctgcttattt
    23581 gaagacgaga tcgaacacac tcaaagagga tttcatgcat tactcgaaga gatccagcac
    23641 ttgcctgaac gtccattgat tgtttttgaa gcaacgggga tttattccag accagtcgaa
    23701 aagttctttc aagatcatca cttttcttac tgtttgttaa acccgttaga agcgaaaaaa
    23761 cagatggaag aaaacacctt atgcagttgg aaaacagata aatcggatgc ccatcggctc
    23821 gcacagactc atcttaaaaa tcaacgtcag ccaaaagaag tacaaagcaa tttttactta
    23881 gagatgcgcg atttagcccg tttttatcaa gaaattgaga agaaaatcac tcgtctgcgc
    23941 atggatttac acaactgcct tcagttgact tttccagagc ttgaacagtt ctttttaaac
    24001 aggctgaccc cttacgcatt gatattgatc cgtctttttc cccatccaga ttttgtattg
    24061 gcatctactc ggacaaaaat aaaaaataaa ctgatcaacg aaacacggaa aaaaatctcc
    24121 gcgaatcgtg ccgagcaaaa ggcagatcaa atcatccact atgcacagtg tgcctatcca
    24181 gctgttgaaa aagacagtat ccactgtcaa aaaacgatct attacgctga acttctccaa
    24241 gatttactcg aacaaaaaga agcactggcg acacaaatga tcaaaaaagc cgaaggctct
    24301 ccttgctttt tgttgtacca aacgttccct gggattggcg cactcacagc cgctttattg
    24361 ctcggtgaat taggagatat cacacgattt aaaacccata aacaattgaa tgcctttgtc
    24421 ggaatcgaca tccgacggta tcattcaggt aagtatactg gccaagaccg catcaataag
    24481 cgtggtaatc ccaaagcacg gaaaattatt ttcttcacca ttcgaaatat gattcgccag
    24541 caacgcgcag ctcctaatca tattgtcgat tattactaca aattaaaaaa gcaacctatc
    24601 cctaagaaag ataaggttgc cacagttgct tgtatgaaca agcttctgaa atgtatgcac
    24661 gctatggtta gggcacatac agagtacgac tatgcgtacg cggtctcagt ggaccattaa
    24721 ctaaaccact tacagtatac cacttctttg cccagatcga aaatttttta cgaacggggc
    24781 tttatttggt gtgccttgat tttgtcgctt tcgtttatga gctatttttc ttacaccttt
    24841 tacttgacta atcgtaggaa agggaactgt gacaaaagtc ttgtcgcagt tcctttttcc
    24901 gaataaacgg tgctcaaaag cttgcatctg cggtaataag tccaaccaag ttaaaaacat
    24961 aaaaagctgt ttttacttgg ctgttcttat tacttgatgc aaggcagctt tttcacaacc
    25021 tctgatacac ggtgttccag aagtaacttc ttcggaaata agccgaaatt tcacaaaaat
    25081 ttgaaaagca attttcttaa attccttctt atttcttgaa gctgcccact tctgacacaa
    25141 cctcctttgt gtaaaagaat cagtttctac tcgatttctt ctatcgtttc ctgcaaacgc
    25201 tgttcatatt ttttgtttcc tttatataaa tcaccaatcg tccatgccaa caggagaagg
    25261 acaagaacaa tgattacata agcgatttga tcagccaatg ctagttgagc tgaggtggct
    25321 tgctcgccga agaaactttc gatttgacct ggtaatcctc gtaaattcaa gtaagtcaga
    25381 ctaatcacag agaaccagcc aagtagtttt acaacaaatg aatttttgaa tcggctcccc
    25441 atctccgctt ggctattggt catcatcagt aaaggaatca tcgagaatgg caatgcaaaa
    25501 gccagaaaaa cttgggattc attcatcaag ttattcaaag cggtatgttc ttcgatcgtt
    25561 ccttttgtac ttgtaaacaa aacacaaatc aatacaggaa tcacagaaag caatcgtgtg
    25621 actagtcttc ttagccaaat tgggatacgc atatggatga agccttccat gatgacttga
    25681 ccggtcaacg taccagtaat agtagagttc tggccagaag caagaagtgc tacagcaaat
    25741 aaagtagaca agataccaga ttttgctaca gcaatcaaga taccattgct catagctgat
    25801 ggatcagata aagcttcata cagaccaaaa aaggaaggat cttggacaga accggttttg
    25861 aatacagcca cacccatgat caatagcagt gcattgacta gaaaagccat tgacaactgg
    25921 atattagaat cccaagtaga aaagcgtacc gcttgtgcta catcttcttc gtcttggtga
    25981 tcgatcttcc gagtttgaga aactgctgaa tgaagatata agttatgcgg catgactgtt
    26041 gcaccaataa tccctaaagc tccagtcagc ggagtttcgc cgccgatgac cggtgagtct
    26101 gagaatgtgt gactgttagg gataaatccg gcaaacaaac tgtgccaatc agggttagac
    26161 aagccaactt gatagacgaa aacgaataaa atgacgaaaa tcaagcagac aaccaaagct
    26221 tcgattttac gaaacccgac ttttgtcagc aataaaagga cgaaaacatc taacacagtg
    26281 ataaatacgg caattaccaa tggaatatca aaaagcaggt agagggcgat tgctgcacca
    26341 atgacttctg cgatgtctgt tgccataatg gctaattcag tcaagatcca taaaatgaca
    26401 cccaatgtct tacttgtccg tgctcggatt gcttgggcca aatccatttg ggtcacgatt
    26461 cctaattttg ctgccatata ttgtaaaagc atagcaatca gactagacat caaaataact
    26521 gacatcaata aatattggaa attttgtcca ccagtgatcg aagtggacca gttacctgga
    26581 tccatataac caactgctac taatgcacct ggtccagagt aagcaagaag tgttttaaaa
    26641 aaactttttc ccttgggtac atccactgtt ccatttactt cagctaaaga taaaccattt
    26701 gtatgttcaa taagtcgatg cttatgaaat tgtttgttgg attgattatt caagaaaaaa
    26761 ccacctttcc tatttatcta cgattacatt ctacacctca gaaagaaaaa attaaagaaa
    26821 aagatttggt atgcctaatt ttttttcgtg gcgtgtcttg ctggttaatg aaagaaattt
    26881 tgttcttctc taaaaaaacc actatttttt gcatgaaact aaagaatacg cctttctttt
    26941 ttcaataaac tttagtaaaa taaatcattg agagcaattc ggaaatagaa aggagagatt
    27001 tatatggtat caacaggtat tgtcgtactt attgctatta ttgctttgct aatcggcgca
    27061 gtaggtggct ttttcctagc gcgtaaatat atgaaagact atttagaaaa aaatcctccc
    27121 gttaatgagg acatgttgcg atcaatgatg atgtcaatgg ggcaaaaacc atctgagaag
    27181 aaaattcgcc agatgatgca gcaaatgaag aaccaaggga aaaaataggt tctgacccaa
    27241 agactttttg cgggctgatt ttttcagtcc gttttttatt tcgtaatttg ttagactatt
    27301 cagactattc agcaaaaaag acaagcacag acaatcctat gctcttgata aagacaaagg
    27361 aggagtaaaa tgtcgatttt tagaaaatta ggttggtttt ttcgacagga aaagaaacat
    27421 tatttaattg ggattttctc cctattcgca gtggccttgg tacagttagc tcctccaaaa
    27481 gtgattggga tcatcattga tgagatcgcc gataaaaatt tatcaataaa gatcatttcc
    27541 tggtggatct tattattgat ccttgcagct ctcttacaat atctttttcg ttatatctgg
    27601 cggacgaata tttggggaag tgcagctcgg ttggagaaag aacttcggca gcagctattc
    27661 aaacatttta cagaaatgga caatctcttt taccaaaaat atcggactgg agatttgatg
    27721 gctcatgcaa cgaatgattt gaatgcaatc caaaatgtag caggagctgg tatcttgacc
    27781 tttgcagatt cagtgatcac gggcggaaca acgatcattg cgatgatttt gtttattgat
    27841 tggcgcttaa cactgattgc gctgattcct ctgcctttac tagccgttac ttcacgagtg
    27901 ctggggtcaa aactccacga tgcttttcgt gattcgcaag aagctttttc tagtatcaat
    27961 gataagacac aagaaagtat tactgggatc aaagtcatta aaacatttgg acaagaaaaa
    28021 gaagatctcg cggattttga agaaaagatt gaagatgcaa ttattaaaaa caaacgagtc
    28081 aattttttag actccttatt tgatccattc attaccttga ttatcggtct gtcttatgtt
    28141 gcaacaatta ttttaggtgg aaagtatgtc ttggaaggca cgatctcaat cgggcagatg
    28201 gtctcattta ttagctatat cggtatgctt gtttggccga tgtttgcgat tggtcgattg
    28261 ttcaacgtat tggaaagagg aaatgcttct tatgatcgcg tcaatgaact tttgcatgaa
    28321 aagacgcata tcgtggaaca actgggtgca gtgcagactc cggcaaaagg cgagctgaat
    28381 gtagctattt cctcttttaa ctatccgaaa gaagaatcac cagcattaga acaaatcaaa
    28441 tttgcgatcc aagaaggaga aacattaggt attgttggga aaactggtgc gggaaaaacg
    28501 acaatcatca aattactgat gcgtgaatac gatgattatc aaggaaaaat tcaatttggc
    28561 ggatgttcga tcaaagaata ttcattgaat gctttattag gatcaatcgg ctatgtgcct
    28621 caagatcact tcttgttttc gatgaccatt cgagataata tccgtttttc taatccaaaa
    28681 ctttcagaag aagaagtaga gcatgcggct tctttagcat ttatcaacaa tgaaatcaag
    28741 gaattaccaa aaggttatga taccttagtt ggagaacgtg gagtctcttt atctggcgga
    28801 cagaaacaaa ggatttcgat tgctcgagca ttgatcaaaa atcctgaatt gctgatctta
    28861 gatgatgcac tttctgcagt agatgccaaa acagaagaag ctatcttgca taatttaaaa
    28921 gaaataagaa aagagaaaac aaccatcatt gcagctcacc gtttaagcag cgtgatgcat
    28981 gcaaaagaaa tcattgttgt cgatcaaggg aaaatcattg aacgaggaac ccatcatgag
    29041 ctgcttgcat taggcggctg gtatgaacga atgtgggaga aacagaaatt agaagcgaag
    29101 atagaaggag gcgaggcctg atggatgaaa attatcaatc ggaatggaca aaatcgattc
    29161 cacttaaaga acagaagaag atcatcaaac gactgatgaa gttcgccaaa ccttttagaa
    29221 gaacgttcat cgttgctatc ttatttgcgt ttgccctgtc tgtgatcaat gtcctattgc
    29281 caaggatcat ccaaactttt atggatgatc atctggctaa acagtcggct acgacacaag
    29341 ttattttgtt ttttgctggt atgtacttgt ttggagtcat agtcaaaagt atcatttggt
    29401 ttttccaatg gtatttgtat tccatggctt cattgaagac ctatcagtat gttcgggtaa
    29461 gattatttga aaagctgcat acactaggta tgcgttattt tgatcagaca ccggcaggat
    29521 cgactgtttc tcgagtgaca aatgacacag aaacgctatt tgaattttgg tatgtctttt
    29581 tgatggtatt gactgggatc tttgcagtcg tttcttcctt cattgccatg tttcaaatca
    29641 atggagaaat tgccttgtgg actttggtgt tcttgccgat tttaggaatc gtcatctggt
    29701 attaccagaa attcagttct cgtatttacc ggaatatgcg ggaaaaatta agtcagctga
    29761 acacgaaatt gaatgaatcg atttccggca tgcgtattat ccagcagttt cgccaagaag
    29821 ctcgtttagc taaagaattt gaacaagtga acaacgagta tttagacacg cgctatgcga
    29881 tgatcaaaac aaattcgatt ctgttaagtc cgatcatcaa ttttctatat gcattggcga
    29941 ttgcgttggc gttgactttg tttgggatcg atgcgctgca ttctcccgta gaagttggac
    30001 tgatctatgc atttacgacc tatgtccagg gattttttaa tccaatgtct caaatgatgg
    30061 actttttgag cacctttaca gatggaatgg ttgccggtag tcgtattttg aaaatcatgg
    30121 atacagaaga atatgcaccg caacaaaatc ctggagcaga tcaagcgatt acttcaggta
    30181 agatcgagtt tcgcaatgta agcttttctt atgatggaga gcacaatgta ttgaacaata
    30241 tctcttttgt cgctaatccg ggagagaccg ttgcattagt ggggcacacc ggaagcggaa
    30301 aaagctcgat catcaacgta ttgatgcggt tttacgaatt ttatgaaggc cagatcttga
    30361 ttgatgatca tgacattcga gaatatccaa tggaagagtt acgtaagaaa atgggattgg
    30421 tcttgcaaga tgccttcttg ttttatggag atatcgcagg aaatatccgg atgatgaatc
    30481 caactatcac agacgaacag attcgccatg cagctgagtt tgttcaagca aacaagttca
    30541 tcgatgaatt accaaaagga tatcactcaa aagtgatcga acacggtgcc agctattcta
    30601 gcggacaacg acagctgatc acttttgcgc gaacaatcgt gacagatcct aaaatactag
    30661 tattggatga agcgacagca aatatcgata ctgaaacaga aggattgatc caagaaggat
    30721 tgacaaaaat gcgacaagga cggacaacga ttgcgattgc ccatcggctg tccacgattc
    30781 gggatgcaga attgatttta gttttagaca aaggtcatat agtagaacgt gggaatcatg
    30841 aaacacttct agcgcaaaat ggtttgtatg cagatatgta caaactgcaa agcagtggtg
    30901 tgtaaaaagt ggttgtgaca gggctccgtt cagctttagg tgataagaaa aaaattgtaa
    30961 aaaaggcttt ccagattttt gcataaattt ggcttatcac cgataagctg gtactggaac
    31021 accgtatatt agaagttggg acagtagcat agtagcattt tgacctaagc gctagagtga
    31081 aaataaaaca gagcttccca gattcttcat ctgtgagcgt tagtgtcgta attaccagat
    31141 ttaaaaaaaa tcacgacagc tagtcagaag tgcccaatag ccgctaagaa agcgttgaca
    31201 aaagtgcttg ctttcgataa tataaagaaa acgatacaac ttggatagtg attgcctgat
    31261 gcaagctaaa cctgatgagt ctcccatggt tccatggacg gctttttggg tttttctttt
    31321 tgttttggat acagccctat atatcatgga aaggagtaaa acatgctgat tgagaaagta
    31381 ctgaataaca acgtcgtaat aaccagggat gaaagaaatc aggaaatgat cgtgatggga
    31441 aaaggtttgg cattcaaaaa gaaagtgggt gacccgattt ttgactcatg catcgacaaa
    31501 aaatttcagt tgacaaatga cggactttca caacagttcc aagaattggc acaagcgatt
    31561 cctcttgagt acttagaaat ttcttgtgaa atcattgaat atacaaaaga ggctctacaa
    31621 gtccagttga atgattcggt gtatattgca ttgacggatc atttgtatac ggctatcgaa
    31681 cgtcacaaaa tgggaatatt tgtaccaaat gtattgctgt atgatatcaa acaactattt
    31741 cctaaagagt atgccatcgg gaaaaaaaca gtgaagaaaa tctcggataa ataccacatc
    31801 aagttatcag aagatgaagc cggatttatc gcattgcatt tagtcaatgc acaaggcatt
    31861 caaagccaac aagacaatac ctacctgttt actacaacaa tacaggatat tctaaatatc
    31921 gtccgctatt actataagat tacatttgat gaagattcag tccatttttt tcgattcgtc
    31981 acacacctac gtttttttct gacacgcgtc ctagatggag aaaaatcaga agtgggagaa
    32041 gtttctgagg aattgtacca ggttattcaa aaaaaatata aggatacgtt tggttgcgtt
    32101 gagaaaatag cagacttttt agccgagata ttcaactacc agatgtccac ggacgaaaaa
    32161 atgtatttaa cgatccatat tgcgcgttta gtgcatgaga atcgttgtaa ataaataaaa
    32221 aaaggaggat aaattaacaa gaacgcatga aataagggta gtgacattca gttggctaaa
    32281 ccttccacta ataaattgga gggaatagaa atgggaaaat atcaagaatt agcgagcaaa
    32341 attgtagaaa atgtcggcgg gaaggaaaat atcaatggtt tgacacattg tatcacaagg
    32401 cttcgtttca aattaaaaaa cgaagaaaaa gcaaatgatg agatcttgaa aaatatggac
    32461 ggtgttgtga cggtaatgcg agcgggagga cagtaccaag ttgtcatcgg gaatcatgtg
    32521 ccagtcgtgt ttgaagaggt tataaaagca ggaaacctta cttttgatga ggctgtttca
    32581 acagaaaaaa tgagaccgtt tgatatgctt attgatggaa tatcgggctg tttccagcca
    32641 ttccttgcta ttctagctgc tggtgggatg attcgtggac tgacagcatt acttgtcttc
    32701 ttaggcgcat ttgaccgcgg ttctggcaca tttgttatgt ttgataatat cggtgattct
    32761 gtattccaat ttatgcctgt tattatcggt ttaacagctg cccgtaaatt taaagtaaat
    32821 gaattcgtag ggatgttgct tggggcagca ttaatgaatc ctagcttgtc gctggaagct
    32881 ttgagtggtg cagcagaagc accactgact accatatttt ctggcactat ttttgaagca
    32941 cctatttatc aaacagtatt cggcattccc tggattgcgc gtaactacgc ttcttctgtc
    33001 attcccatta tctttattgt gttgttagct agccaaattc agaaaccaat taaaaagtta
    33061 gtacctgaga tgatcgcgaa tttcttcgtt ccattcttca ccgttcttat tacaatgccc
    33121 ttaggttttt tactcgttgg accagcattc acattcgcaa ctgatatttt aatggctgga
    33181 tttgaaacac ttttagcact ttcgccagtt atttatggag caatcgtagg cttcttctgg
    33241 caaattctag tgatgtttgg tctccattgg gcaatcgtac caatgggatt gatgcaattt
    33301 tctgtgaatg gttggcaaaa tatcatgaca cctgttgcag tagtgtcttt tggacaaact
    33361 gcagcactta ctgcactcta ctttaagctt agaaacccaa aagacaaagc aatcgcaata
    33421 ccagccattg tttctggtat tgtggggatt acagagccag ctatttatgg gtttacattg
    33481 ccacgtaaaa aaatatttat ttttacctgt gtcggtggtg cgttaggggg cgcgtatagt
    33541 ggattaatga atttaacttc ttggaatcca ggtggattag gcatctttac aattcccaac
    33601 tatattagac cagatggtga tttaacggat gtgattaatg tattgattgg aatcgccatt
    33661 gcgatggtgg tatcctttgc gctgactttt ttcttttgga aggaggaagc aggtgaaaca
    33721 gatgatagac agaaaagatc aggtaaagaa attgtaaaaa caccgataca aggacaaatc
    33781 gctccactga atgcagcaaa ggatgcagct tttgcacaag gaacactagg tcgaggaatc
    33841 ttgatctacc ctgaaaaagg agaagtacgt gccccttttg acggaacagt catgaccctg
    33901 ttcccgacga aacatgcaat cggaatggtt tctgaagcag gtctggaatt gctgattcat
    33961 gtcggattgg atactgttca gttggaaggg aaatattttg aaagcttggt gcagcaagga
    34021 gaaagagtga aacaaggcga tctgttgctc cgcttcgaca aaaagaaaat cgaagaggaa
    34081 ggatacagtt tagaaacacc tgtgatcgtc accaattaca cggattattt ggatattttg
    34141 gaaaatcaag gggagacggt cgggccagac gatgcactta tcaccgcact gacctgaacg
    34201 gttaggtgaa agaatggact aggcttaatt attcttttta gtccacttct ttattttcaa
    34261 aattgaaagg ctctttcatg atggctgagc tgatagggcg tttatcaaat ttttgtccta
    34321 cagaaattag atggactaaa ttctgttgat aattttctgc aaaaacacaa ctatataaca
    34381 cgtctagaag ataacaaatc gatgtattga tcgtaaaatt accaattttc gaatacagtc
    34441 gttcgcgtgt cgtaagtcgc aaagcggctg tactcattga agatagcgtt gaatcaccga
    34501 tactggtcaa agctaaaatt ggaacatgat tttgtttcaa tatttctgcg gtacgaagga
    34561 tcacattgtt ttcacccgta taagaaatca gaatcccgca catatcactc gtgcaattgt
    34621 acgcttcata gaacgattca ccaaaagtgg tgacaatcgt gacatccatt ttgatgcgct
    34681 tcattttcag catgaaatct tgagaaatca aagtattcga gttactggcg aaaatcacga
    34741 ttttttttgc ttgaagcatt agttgtttgg ctttttgcag ttggtcatga tgaatgagag
    34801 aaagtgtatc ttgaatcgtc atctgttcta aagaagccat tttatttgcg atcgtcataa
    34861 taccgtctgt ggtggaaaaa ggaagattcg catctacgtc ttgaaaattc ccttcaagat
    34921 aggctgtttc agctaaaaaa gcattacgaa aactgaccca gccatcaaaa cccatttttt
    34981 ttgctacacg gatgagtgtg gacgggtgga cataacatcg ctcagcaatc tcttggatgg
    35041 tcatttcgcc aagtgctgga gaatcgctta agagaaactg aatcacttca ttttctgaag
    35101 gagaaaagga gatttctttg attttttcac gtaataacat gtagatacct tcttcttgtt
    35161 tttttacgta aattataact tttttgaaaa tgatttgtaa acggatttat gttatatagc
    35221 ttaataaaga cattttttga caagatattt acaaaaatcc agtagaaaac actaactttt
    35281 gtaaatgtta ctggaaagaa acgaatttct attgtttgtt ttgtttacaa aaaagataat
    35341 aaaagtgtaa aaagtaaagg agtgagaaca tggcaaaagg aatcaaaatc gctacgattg
    35401 gtggaggcag cagttacacc cccgagttga tggaaggatt tatcaaaaga tatgaggaat
    35461 taccgatacg agaaatctgg ctcgtagatg tagaagaagg aaaagaaaag cttgagatcg
    35521 tcagtcagat gtctcagcgt atgtgggatg cttctccgta tgaagtcaaa atctatgcaa
    35581 ctctggatcg ggaagaagca ttgaaagatg cggattttgt tacgactcag tttcgtgtcg
    35641 gtcaattaga tgcacgaatc aaagacgagc ggatccctag ttattatggg atgattgggc
    35701 aagaaacaaa tggtgctggc gggatattca aagcttttcg taccgttcca gtggttttgg
    35761 caatcgttga agacatgaag cgtttatgtc caaatgcttg gctgatcaat ttcgcgaacc
    35821 caagcgggat ggtgacagaa gcagttatca gatatggcaa atgggataaa gtgataggat
    35881 tatgcaatgt gccagtaatg gcgatgatga cagaaccaac aatgcttggc aagaaaaaag
    35941 aagagctgat ctacaagttt gccggtctaa atcacttcca ttggcacaaa gtagcagata
    36001 ataaaggaaa tgaccgcacg gcagaattga ttgatcgttt atacgatgaa gacaatggat
    36061 tgccgaaaaa tatctttgat atcccgtttt tcaaagaaca attaaaacaa atgaacatga
    36121 tcccttgtgg ctaccaccgc tattactacc gtgaagaaga aatgctggaa catgctttag
    36181 aagaatatca aacgattggt acaagagcgc agcaagtgaa agaaacagaa gcagagctgt
    36241 ttgaattata caaagatcca gaattggatc ataaacctga acaattgcaa aaacgaggtg
    36301 gtgcttatta ttcagatgct gcctgtgaaa cgattgcttc gatctatgga aataaagaaa
    36361 cacagatcgt ggtatctaca aagaatgatg gagctgttcc tgatctgccg gcagattgtg
    36421 tagtagaagt cactgcctat gttggcgcac aaggcgcacg aaatgtagcg tttggttccc
    36481 ttcctgctgc tgaaagaggc tggttgcaag taatgaagaa tatggaattg ctgacgatcg
    36541 aagcagctgt gactggtgat tatggaacag ctttacaagc gtttacgatc aatccgctta
    36601 tacgatcagg aaagacagca aaacggatca tgaatgagtt gtttattgca catcagcagt
    36661 atttaccgca attcaaggaa acaatcagcc ggttaaaagc agaaggaatc gaagtccaag
    36721 atgaactggc aagagaatta tcaagcaata cacatgtaat ggaggaagta tgatgggatt
    36781 cagaaaagat tttttatggg gcggagctac agcagccaat caatgcgagg gcggttatga
    36841 tgaaggcgga cgtgggttag cgaacgtaga tgttgtgcca atcggagaag accgttttcc
    36901 tgtcattact ggaaaaaaga aaatgtttga atttgatgaa aatcattttt atccagcaaa
    36961 aattgcgatc gatatgtatc atcattataa ggaagatatt gctttatttg cagaaatggg
    37021 gttcaagact tatcggatgt ccattgcttg gagtcgtatt tttccaatgg gcgatgaaaa
    37081 agagccaaat gaatctggtt tgaaatttta tgaggatgtc tttaaagaat gtcaaaagta
    37141 cgggatcgag ccgcttgtga cgattacaca ttttgattgt ccgatgcatt tgatcaaaga
    37201 atatggtgcg tggcgttcca gagaactcgt tggtttttat gaaaatctgt gccgagtcat
    37261 cttcaatcgc tataaaggac ttgtcaaata ttggttgaca ttcaatgaga tcaatatgat
    37321 ccttcatgca ccattcatgg gcgcagggct gtattttgaa gaaggagaaa atgaagaaca
    37381 aatcaaatat caagcggcac atcatgagtt ggttgcaagt gccatcgcaa cgaagattgc
    37441 tcatgaagta gatccggaga acaaagtagg ctgtatgctg gcagcaggag catattatcc
    37501 atacacttgc aatcctgaag atgtttgggc ttctagaaaa tcagatcgag aaaattattt
    37561 cttcattgat gtccagtcac gaggagaata tcctgcttat gcattgaaag aaatggaacg
    37621 aaatggcatt cagatcaaaa tggaacctgg ggatgccgca ttgctgaaag aacatactgt
    37681 tgattttatc tccttttctt attattcttc tcgagtttcg actactgaca acgaactctt
    37741 ggaacagact gcaggaaata tctttgcttc tgtcaaaaat ccatatctgg aagcaagtga
    37801 atggggttgg caaattgatc cattaggctt gagaataacg atgaatgata tttatgatcg
    37861 ttatcaaaaa ccactattta ttgtagaaaa cggcttaggt gcagtcgata cgcccgatga
    37921 gaatggttat gtggaagatg actatcgaat cgactatctg gcagcacata tccaggcaat
    37981 gaaagatgca gtagaattag atggagtcga tctattaggc tatacgactt ggggatgtat
    38041 tgatttagta tcagctggta caggtgagat gaagaaaagg tacggattca tttatgtcga
    38101 tcgtgacaac gaaggaaatg gcacattagc ccgttcgaag aagaaatcat tcaactggta
    38161 taaaaaagta attgattcaa atggagaaaa tctttcgaat gattgatcaa tgatttataa
    38221 aagtctattg tttttcagcg gatttttcga gtataataaa gctattcgag aaacgcaagc
    38281 agaacaatag actttttttc gcattggctg taaagtatgc ttacttgatt aagtaaagga
    38341 gaatctacat atgtatgatg taatcgttat tggcgcaggt cctgctggga tgactgctgc
    38401 tttatatgct tcacgttcaa acttatccgt attgatgatc gaacaaggcg cccctggcgg
    38461 ccaaatgaac aatacggcag aaatcgaaaa ctatcctggt ttcgattcaa taatgggtcc
    38521 tgatctagct tataagatgt atgaaggtgt ttcaagattt gggacagaaa atgcttatgg
    38581 aatcgtgcaa gatatcaagg atcacggcag ccacaaagaa gttatttgtg aagataaaac
    38641 ttacgaagga aaaacagtca ttatcgcaac aggctgtatc caccgtaaat taggcgtacc
    38701 tggcgaggaa gaatttgctg gacgtggcgt ttcttactgt gcagtttgtg atggtgcgtt
    38761 tttccgtaac aaacgtctag tagtgatcgg aggaggagac tcagcagtag aagaagccat
    38821 ctatttgaca caatttgctt ctgaagtagt catcgtccac cgtagagatg aattacgtgc
    38881 acaaaagatc atccaagacc gtgcatttgc gaatgaaaaa atttccttta tgtgggatac
    38941 agtcgttgac gaaatcgttg ggaatgaaat ggtagtgaca ggtgtgaaag cacgtaatgt
    39001 caaaaccggc aatgagtttg atttggcagc agacggagta ttcatctatg ttggactgga
    39061 tccattaact gcaccattta gagaagcagg gttgacgaac gaagctggct ggattccaac
    39121 agacaacgaa atgaagacga atataccagg cgtttttgcc atcggagatg ttcgtgaaaa
    39181 agatttgcga caaatcacta ctgctgttgg tgatggtggg atcgctggac aacaagtgta
    39241 taaatacttg gaatctttag aagaaacaac tgcataagtt taaaaagagt ggaagaacgg
    39301 tttaattgtt cttttactct tttttttcgc gtgaaatcta ctgaatccga tttatgcgaa
    39361 tacttgcaac cgtgcttgat aaaagaatcc tttcttgatt taagcgtttt ttggtcctca
    39421 tactttcata tctaataagt gaatgctata cttattaaga accatatttc agaaagaggt
    39481 gttattttca tgtcttggga acaagtgtat gaacaatggg tacatgaaga aaatttagaa
    39541 gaaaacttaa aaaaacaatt aaatgatctg ggtgaagatc ctgaaaaact tgaagatgct
    39601 ttttatgcac cgttggaatt cggtactgca ggcatgcggg gaatcttagg gcctgggatc
    39661 aatcgaatga acatctatac ggtaagacaa gcaacagaag gacttgcacg tttcatggat
    39721 acacaaggcg aagaaacaaa acgccgaggt gtcgctatcg cttatgactc acgccatcaa
    39781 tcaccagaat ttgccatgga agcagccaaa acattagcac atcacaatat cccatcttat
    39841 gtattcgaaa gtctacgtcc aacaccagag ctttcttttg cagtccgtca tttgaagacg
    39901 tttgcgggaa tcatggtaac cgcatcccac aatccagcag cttacaacgg atataaagtc
    39961 tacggagaag atgggggaca aatgcctcct gcagacgcag atgcattgac gaaatatgtc
    40021 cgtgaagtca gcaatccgtt aaaagttgaa gtattatctg acgaagaagc tgaacatagc
    40081 ggattgatca cgatcatcgg agaagaagtg gatgccgctt atctagaaga aatcaaagca
    40141 gtaacgattg atcatgaatt ggtggaaaca atggggaaag atttgaaact tgtgtacaca
    40201 ccacttcacg gaacaggaaa aatgttgggc gaacgtgcgt tgaaacaagc tggattcgaa
    40261 caattcgtac tagttccaga acaagctgtc gcagacccag atttcactac agtcaaatca
    40321 ccaaatccag aagaacactc tgcttttgag tatgcgatac gacttggcga gaaagaaggc
    40381 gctgatttgc tgattgcaac agatcctgat gcagaccgtt taggtgcagc cgttcgtttg
    40441 ccaaatggct cctatgaagt attgaccgga aaccaaatcg gagcactgtt tgctcaatat
    40501 attttggaag cacaccaatc gcgaggcact ttacctgaaa acgcagcggt attgaaatcg
    40561 atcgtttcta gcgaattacc tacagcaatt gcggaacact atggggctac catgttcaat
    40621 gtattgacag gattcaaatt cattgctgaa aaaattcaac aatttgaaga agatcattcc
    40681 catactttta tgttcggatt cgaagaaagt tacggttatt tagttaaacc tttcgttcgc
    40741 gacaaagacg cgatccaagc attgctctta ttagcagaag tagcagctta ctataaaaaa
    40801 caaggcaaaa cgttgtatga tggcttgcaa acgatttttg aaacctatgg ctactacgca
    40861 gaaaaaacga tttctgtgac aatgagcgga caagaaggtt ctgcgaaaat ctctgctttg
    40921 atggaaaaat tccgtgaaga agcaccaaca gaatttgccg gagcaaaagt catccaaaca
    40981 gaagacttca aagagttgac gagaacagac cgtgaaggaa acgtagaaaa actaacgaca
    41041 ccgccatctg acgtattgaa gtatacgctg gaagaaaatg gctggatcgc tatccgtcct
    41101 tcaggaactg agccgaaaat caaattttat atcggtgtaa aaggaaactc ttcagaagac
    41161 gcagctgaaa aagtagccgc ttatgaaacg attatccaaa agatgacaga agaataaaaa
    41221 aacttgagac tgatggaaaa agtggtaaac tttagaagtc agtctttttt caagttggag
    41281 gtgaatggat tgccagacac gcaaaaaaca aaagtagaga aagtcagcca actattcaaa
    41341 atgttgagtg accccactcg tctcaaaatt ctgctgtatc tgaaagacgg ggaacaaaat
    41401 gtgacagcaa tcatccaagc agtggaaatg gaacaatctg ctgtatcgca tcaactgcgt
    41461 ttattaagag aaaaccatgt cgtcaagtcc catcgtgagg gaaaagcgat tttgtatagt
    41521 cttgatgatt ctcacgtact ggatattttg aaccagacac tcaaacatgt ggaacatcaa
    41581 taacgatagg tgcaaataga gacaaactgg actgtgtcaa cgaatcttct tcgctgacac
    41641 agtccagttt ttttaaagaa aaattgttag tctgtttctt cggtggtttc agttccataa
    41701 taactatggt cttctaggtc taaagcattc aaaataagcg aagctgtttc ttcaatagat
    41761 aaagaagcga cattgattac tacgcagccc aatttttcat aaagatcatt cgcaaaatcg
    41821 agttcagctc gtattttttc gatatcggaa taagcagtat caggatttaa tccgtaagag
    41881 cgcatccgtt ctttacggat attgtttaaa atatctgggt tattcgtcag tcccacgatt
    41941 tttttaggat cgatctccca aagctgtttg ggaatatgtg cttgtgggat caaaggtaga
    42001 ttggcaactt ttaaattttt gttagctaaa aacaagctca aaggcgtttt ggaagttcgg
    42061 gatacgccta gcaaaacgac atctgcttct agaaacccac gaggatcttt cccgtcatcg
    42121 tattttacag caaattccat tgctttgatc cgtttgaaat agttctcatt caataaatga
    42181 agggcgccag gttgccgaat gggcttgata ccagttaagc gctcgatttc tgatatcggc
    42241 ggagtcatca catcaaaact aaataattga tgttcttcac aaaaagaacg cgtcatctcg
    42301 atcaattctt gattgatcaa tgtgtgcagg acaagagctt tttcttctag tgcatcttgc
    42361 agtgcctgca tcaatgtttt ctcatctgtc acaaatgttc tgcggaataa attgaactca
    42421 acgctaggat attgggccat agtggcttgc gctagttttg tcgcagtttc tccagcagag
    42481 tcggagatga caaaaaaagt aacgatttct gtagaatcgg aagacatgga taaaacctca
    42541 cttgcatttt ttttatgttt attataccat actctagaat gtgtacttcg taatcatttt
    42601 gatttggagg aataagtcat gaaaaaacag acgttgatcg aacaatcact agaaacattg
    42661 aaaaataacg gttttaaata tactaaaaaa agagaagcat tgttaactta tttagtgaag
    42721 cgcaatcgct acgtatccgc taaagaagtt tttgactata tgaatcagga attcaaagga
    42781 gtaagttacg atacgattta tcgaaatctc catgattttg cagaaatcga tttactggaa
    42841 gaaaccgatt taaatggaga gatgaagttt cgttttcatt gctgtcaagg ggaaatcggc
    42901 catcaccatc actttatctg tacggtgtgc ggaacaacga aagaaatcca tatgtgtcca
    42961 atgaattatt tcgaagaaca gctcggtgga tgtacgatcg aagggcatag attcgagatt
    43021 ttcggaagat gtgaaaattg tcaataagga tttaaataaa ataacatttg ataattttaa
    43081 aaaaaagcaa gatttccttg acggtcaaaa cagcattaga tataatattt acaggacagt
    43141 cttgtttttt gagatatatt tcaataacaa ttacggttac tttttaagct cggagggagg
    43201 gaattaacat gtcaaaaaca gtcgttcgca aaaacgaatc acttgacgat gctcttcgtc
    43261 gcttcaaacg ttccgtgtca aaagcgggta ctttacaaga atctcgtaaa cgtgaattct
    43321 acgaaaaacc aagtgtaaga cgcaagaaaa aatctgaagc agctagaaaa cgcaaaaaat
    43381 tctagttctg tgatgaattg gagttggtag tgtgtcacta ctaagtagat taaacgatga
    43441 catgaaaaca gcgatgaaag cgaaagataa ggaatcttta caagtcatcc gaatgatcaa
    43501 gtcatctata caaaacgagc agattaaaga aggtcacgac ttgacagaag aagaagaatt
    43561 aacggtgttg tctcgcgaaa tgaaacagcg acgtgattct ttgcatgagt ttgaagaagc
    43621 aggacgtgac gatttagctg aaaaagtaaa aagtgaaatt gtgatagtcg aaaaatacat
    43681 gccggaacaa ctttccgacg aagaaattcg acaacttgtt caagaagcaa tcacgcaaac
    43741 tggtgcttca tcaatgaaag aatttggcaa agtcatgggt gcgatcatgc ctaaagtcaa
    43801 aggaaaagca gatggaaacc aagtaaatgc cattgtgaaa gaactattac aatcttaatt
    43861 ttatcattta aactgcggac aatcattgtc cgcagttttt ttgtgctcgt aaaaaagaga
    43921 tctaaaaaat agctagacga aagaatagga ttctttcatc tagctgtttt tttcctgttt
    43981 aatatttctt atgttaaatt gtgtttgatc tggttattct tctggtagtt catttgcttc
    44041 ttgtttatac cctgataggc gataggcgta atagaagagt aagctgccag catacccaag
    44101 taacgttggg accatccagc caagtcccaa tgcagcaaaa ggaacgtgat gatgataaaa
    44161 ttcgagcatg cttgctacaa ctctttgttg actcactaaa gcaggcgaat ttgccagcat
    44221 atccaatacg gcgggaacag cagcaaacaa catcgttact tgatagacaa atggtgtctt
    44281 ttggaaaaat tttgctgtta aggaaagcaa aatcaacgca agcgacaatg gatacaaaag
    44341 catcaatact ggtaaagacc attggatgat attgtccaaa ccagcatttg caacgacaaa
    44401 agagacgaaa gtcgttaacc gcagccatgt catataactg actttaggga acagtttatg
    44461 gaaatcttgt gcaaaagaaa caacgagtcc catagcggta gtgaagacac ctaatgtgac
    44521 catcactcct aagaagctag cgccgaagtt acctaaataa aaattagtga tctgagaaag
    44581 tgcagttccg ccattttctg ataaagacat cttattcaaa ctcatcgcac cgagaagaac
    44641 aagaccaaaa tagatcatga cttctagcgc aacgctcagg ctaccagctt ttgctgttaa
    44701 ttctgtgact tttttatctt tgaaaccaag gtcacggact gcatggacaa aagtgacact
    44761 taaggcaagc aaggctactg catcaaccgt gttataacct tctaggacac catttgttaa
    44821 agcgtttgtt tggtaagtat ctgcagcaga ttgatttaga tttcccattg ggtggaataa
    44881 agaaacgaca aaaatgattg ctaataatgc aagaaacaag gagtttagat actttccgac
    44941 gtatttgacc aaccgtgtgg gatggacagt aaggaaataa gcaagtaaaa agaaaagagc
    45001 agagaataaa aacataccta atgaattata tttttcaggc aaaaatggtt tagcagccat
    45061 ttcaaaagca gtagcagctg tccgtggtgt accgaaaaat ggtccgatcg tcaaatgaac
    45121 aaggattaag aacaaggcag cataccattt tccgacaggt ttagctaagt catacagacc
    45181 atcacttttt gtcactacta cagctaagat agctagtaat gggaaaagag cgcctgagat
    45241 ggcaaatcct acgccagcac tgacccagtt tgcgccagcc atttgaccta agtggacagg
    45301 aaagattaga ttacctgacc cgaaaaacat cccgaagata agtgaactga ccatcaatag
    45361 ttgtttccat gaataagttt ttgtttcttc cataaatttt tcctccaata attatcattt
    45421 tgattgacga tataaacgtt gcagcaatta gtaatgccac taatatcaga ttccatgaaa
    45481 accaccacct taaaatataa aaaaaagccc ttttccactt gggaaaaggg ctctagattc
    45541 tagaacggta ccaccttttt tcgcttaaaa aagcttcttc attcacggac gctttttgat
    45601 aaagttatcc gctagcctga taatggaggc agccacaatg atctacgttt tcgacattga
    45661 ctcggaaatg atgttcgtct attcgattta ttgtcatttc tcacttacat gactcactgg
    45721 gaataaatcg ttgaatagcc tactgttttc ctcgacgctt tgctgtatgt ttatttgttg
    45781 acgtaataat acacctgttt tttttgaaat gcaagaatat tttaactatt ttgttttctt
    45841 tttttgaaac aagaaaaata cctagagaat acctctgaat gaaacggaat attttgttct
    45901 ccactttcat ataacttaca ttctcagatt ctttttatca aaacgagacc tttagcgaat
    45961 ggaaacagct attttttaac gtttcttggt acgtatggtt aaacgactct tttacaacct
    46021 tttcttattt gctatatagt ttcttctgag tatggtaaaa taggaaagaa tgaatcgaaa
    46081 aaaaggggat gtctattttt gacggaagag tctagttctt tagagattag attgacagct
    46141 gctgatgatg tcagcatgct tttaggtgca cacgacaagc atataaaact gatcgaggaa
    46201 acaacggaaa caaccatcca tacacgtgga gaaatcattc agatcattgg tgaacaatcc
    46261 cagatttcct tggctgcctc agtcattcgg acattacagg aattgatcaa acgaggaatc
    46321 cacgtaagta caccagatgt cgtgacggca ttgaaaatgg ggcaaaaagg tacattagat
    46381 tattttgttg agatgtatga ggaagagatc gtcaaagacc gtaatggaaa acctatacgg
    46441 gtaaaaaaca gcggtcaaaa gaaatacgtt gaatcggtag ccaaacatga catcgtattt
    46501 ggtgtagggc cagccggaac agggaaaacg tttcttgccg tagtattagc aattgctgcc
    46561 ctaaaaaaag gcgaagtgca aaaaatcatt ttgacgcggc ccgctgtaga ggcaggggaa
    46621 aacctaggct ttctacccgg ggatctgaaa gaaaaagtgg atccttatct gcggcctgtt
    46681 tatgatgctt tataccaaat ttttggattg gatcatacga accgattgat ggaacgaggc
    46741 gtaatcgaaa tcgcaccatt agcttacatg cgggggcgga cattggatga tgcattcgtt
    46801 atcttggacg aagcacaaaa cacgacagtc gctcagatga aaatgttctt gacccgtctc
    46861 ggttatcaat caaaaatgat tgtcaatggg gatacaagtc agatagactt gcctcgaggg
    46921 acgacaagtg gtcttgttca tgcagaacga acactaaagc aaatcaaaaa aatcgatttt
    46981 gttaattttg aagcaagtga cgttgttcgg caccctgtag ttgccgaaat catcaaagct
    47041 tatgaaaagg cggatcttca tcaagaataa gctttgctta ggaggataag cacatgttga
    47101 ataaaacact gcagaaacta caagaaaaac tcggaaaggc agcattgcct ttccttctgt
    47161 tcttgttttt tatcattgtc tgcggcgtta catttagtag tgtcaaacaa aaggccaatg
    47221 atttcagaga aggccaagta gcagaagaga gtatccgtgc gaataaaacg atcgagaaca
    47281 cggaagaaac cgaacaaaga agaaaactgg cagcagaagc agtgactcca gaatatactt
    47341 atcaaaaaga tctggcagat gaccagaaca atcggatcaa gcaattattc gaattgatcg
    47401 ataagacgaa tgataccatc aacaaatctt ataatgacaa ggtagataag gcgaaggaag
    47461 atgaaaatat cccgaaacct actacagaag agcggattgc tacactgaag aaaaattttg
    47521 aaaacgtgaa tgcagaaaac gttgcgtttt accaaaaact gccgaacaat ttttattcga
    47581 cgatatttga aatgactgaa acggaaattc acacggttag ggatgaaagt ttgaagctca
    47641 ttgacgaaca gatgagtaaa caagttcgtg aaagcgaatt ggaagctttt aaacaagaag
    47701 cagaagatca gattcagtat ttgaatgtca caacagagca gcaacaaatg attcgctact
    47761 tagtggatca aggcattgta gtcaatgatg tattgaatga gaaaaagaca gaagaattaa
    47821 aacaatctgc acgagaagct gtacaaccag tgatgatctt ccaaggagaa atcattgttc
    47881 gcgaaggaaa tcaaattgat gcttcagcga tgaaaaaatt ggaattacta ggattgacga
    47941 atcaaacgac ttcgattttc ccactcattg ccatggtttt agctgttttg cttcaaatcg
    48001 gcgtactgat ttataattca cttcaattcc aaaatgcagg agaaagaaca aaatacgtgc
    48061 ttttctatgt gacagctatg tcagtcagca tagtgctgat gaaatttttc caattattcc
    48121 aaacggaaca agctacttat atcccgctgt tttatcccgc tgcttttgca ccacttgttt
    48181 taagcttttt cttgaaccga agagcaggga tcatggctgg tattttccaa gcagtatctg
    48241 cacttttcat tttttatgat tcgattggca cgaactttct aacgattatc ttgatgtctt
    48301 atgttttctc tgggctcatg gcaacgattg tcagacgcaa acggatctca gaacaaggat
    48361 tatctgctgc catgtgggtc attatttttc ctgtgatgat ggatgtcatt ttgatcgtct
    48421 atcaaggaat gagctttggt gatgcaacga cttggttaat gcttgtctgc gggttcactg
    48481 gtgcactctt ctcattcttg ctgacgatcg gtctacaccc atatattgaa ttgatggtca
    48541 atgatgacag tgtaattgta ttaaatgaac tcagcaatcc aaatcatcct ttattgaaac
    48601 agttgctgga agaagcgcca ggtacttatc atcatagtat gatggtagct aatctaagtg
    48661 ctaacgctgt agcagaaatc ggcggacgtt ctttgctaac tcgagtagct tgctattatc
    48721 atgatatcgg caagatcaaa catgctagct ttttcgttga gaacttgcct tcaggagcgg
    48781 aaaacccgca caatttctta ttgccagaag acagtaaaca tattatcttt ggacatgtga
    48841 cagatggagc caaaatattg gaagattata atatgccgca aatggtgatc gatatttgca
    48901 aacagcatca tggaaccacg ctaatgcgtt atttctacat caaagcgaaa gaacgcaatc
    48961 cggaagtaac agaagagcaa ttccgttatc ctggaccaaa accgcaaagt cgtgaagcag
    49021 ggatcgtcaa tattgctgac agttgtgagg ctgcagtacg ggcaatggat catccgacga
    49081 gcgaaaaaat cgaaagtttt gtccataatc ttatcgaaga gcgtatttcc gatggtcaat
    49141 tagacgatag tggactgacc ttgaaagaaa tccgaaaagt ggaaaaatca ttgatcagcg
    49201 gtttaagtag caccttccat tctcggatca aatatcctaa aatgaaaaca gaagttgaga
    49261 agataaagga agaacaagaa gaatagaaag aagcgatgta taatggatat tacctttatg
    49321 gatgaaacaa accaagtctc agaagagaaa atgaaagaaa tcgatgactt gctgcaattt
    49381 gcagcatctt atttaaagct gccagaggaa acagaaatgt ctgttacttt catggacaat
    49441 gcggcaatcc aagtaatcaa tcgtgattac cgtggaaaag atgcaccgac agacgtcatc
    49501 agttttgctc tggaagaaga aggcgaagac gaaatcccag tgatttttga agatggagag
    49561 aatcctttgc ctcgtgtact aggagacatc atgatttcta ttgaacgtgc tgctgaacaa
    49621 gcagaagctt acggccattc atatgatcgg gaacttggct ttttagcggt acatggattc
    49681 ttgcatatca acgggtatga ccatatgaca ccagaagatg agaaagaaat gtttggttta
    49741 cagaaagaga tcttggatgc ctatggactc aaaagataaa aacgtagaga aaaacaaaca
    49801 tttcctgatg tctgtggaat ttgctgtcca aggagtcaaa accgtttttg aggaagaacg
    49861 caatatgagg aaacatgttg cgttcggtat ccttgcttta tttatgggcg tgattttcca
    49921 gcttgatcgg atagagtggt tatggctgct tttagctgtt tttctcgttt ggatagtaga
    49981 gatcatcaat actgtttttg aaaatgtagt ggacatgttt acggattttc attttcatcc
    50041 gattgggaaa aaaatcaaag atatggcagc tggagcagtt ttagtgaccg cttgttttgc
    50101 tgtcatcatt gggttgattt tatttgtccc taaaatatat catttgttgt ttaattaaaa
    50161 aggagaacgt atatgccaga acataaatca gggtttgtcg caatcgtcgg ccgcccgaat
    50221 gtaggaaaat ccacattatt gaaccgaatc gtgggtcaaa aaattgccat tatgagtgac
    50281 aaggcacaga caactagaaa taaaatccaa ggagtatata ctacaccaga agctcagctg
    50341 atttttatcg atacaccagg aatccataaa ccaaagcatc gtctaggaga ttttatggta
    50401 gaagcagctt acagtgcgtt gaaagaagtg gatgcagtct tatttatgat cagtgctgat
    50461 caaaaacgcg gccggggaga cgattttatt attgaacgtc taaaaaacgt gcattctcca
    50521 gtttatctga ttatcaataa aatcgataag atccatccag acgagttgct gggaatcatc
    50581 gaagattatt cgacgcagat gccttttgca caagtgattc cgatctctgc tacagaagga
    50641 aacaatgtcg aacgcttaat ggatgtatta gtcagtgaaa tgccagaggg cccacaatat
    50701 tttccagatg atcaagtgac tgatcatcct gaatacttta tcgtttctga attgatccgt
    50761 gagaaagtct tgtttttaac acgagacgaa gtgcctcatt ctgtcgcagt cgttgttgat
    50821 tcgatgaagc gaaacgagaa tgataaaatc catatccagg ccacgatcat cgtcgaaaga
    50881 gatagccaaa aaggaatcat tatcggcaaa ggcggaaaaa tgctgaagca agtaggaacg
    50941 aaagcaagaa aggatatcga aaatctttta ggagacaaag tatttctaga actttgggtc
    51001 aaagtccaaa aagactggcg agacaaaaaa gtctatctgc aagactttgg ctaccgaaaa
    51061 gacgaatact gatattctga acttcttata ggttaagtat agaaataaac tggataaaaa
    51121 tccgcacgtt gagaaaaacg gcggaagatc gaaacataaa taatctggat cggcagaatc
    51181 tgcttttcca gatttatttt ttaggaggga gaatatgagc cagcttgcag aatcgaaagg
    51241 cttgatttta tctagccgta attacaaaga aaaagataaa ttagtcaaaa tctttacgga
    51301 atcttctggc aaaatgatgt tttatatcaa aggaatccat cggcaaaatc agccattagc
    51361 tccggctttg ctccccttta ccgaagcagt ctatatcggt aattttcgaa gtgaaggttt
    51421 gtcgttttta agcagtgtca aagacgtcca tgcgtttcgg aacatccaag aagatatctt
    51481 tttgagcggt tatggtacct atttgctaaa tctagtagat gcagcaatcg aagatcatca
    51541 atatgacccg catttattcc aatttacgca acaagctctg cagcggatgg atcaaggaga
    51601 tgatgcagaa atcatcacga atatctttga agttcaaata ctgcaacgct tcggaatcgc
    51661 gccaatttgg acgcactgtg tcgtatgcgg ggaaacaaaa ggaaaatttg actattcttc
    51721 caaatctggc ggtgtgatat gcgagaaaca ctggccaatg gacgaacacc gttatcatgc
    51781 agatcctcgc gctgtttatt tcgttcgaat gttttcggct atttcttatg ataagatcag
    51841 tggaatccac ttgaaagaag aaacgaagca ggcaatccgt gacctcattg accagttgta
    51901 tgatgaatat gtcggtattc atctaaaaag caaaaagttc attgatcaaa tgaagtcttg
    51961 ggcacacgta ttaaagacgc cagagaaaaa tatgcctgaa aaagagatac ctgaaaaaga
    52021 agaataaatg aaagatacaa caaaaaaatc aaaactattt gacaaataca gggacttccg
    52081 tctattatta accgtagatt aaatagatcg ttcactgaga ggatctatta tataaacaag
    52141 aaaactgcaa aatgaatacg tacattgacc aagatcagta aaaaacacgt ggtttagcga
    52201 gttcgggaga gtggaagccg gacccaaacg atttttgaag aggcacttgc gagtacgata
    52261 aatgaagctg ccgaatcttt attcggaagt agggtggaac cgcgaaatta ttcgtcccta
    52321 tgtctgtaat cagacatagg gactttttgt cgttttcttt cctgtattct tattgacagc
    52381 aacgcttaaa aattgaaagg ggcaaaacag atgagtaaaa aattgaccgt ccaagatatg
    52441 attttaacat tacaaaaatt ttggtcatca aacggctgca tgctgatgca agcttatgac
    52501 acagaaaaag gagcaggtac gatgagccca tatacattct tacgggcaat cggaccggaa
    52561 ccatggaatg ctgcttatgt agagccatcc cgccgaccag ctgacgggcg ttatggagaa
    52621 aacccaaacc gtttgtatca gcatcatcaa tttcaagtcg taatgaaacc ttcacctgaa
    52681 aatatccaag agctttattt agaaagcttg cgtcttttag gaattgatcc attagaacac
    52741 gatattcgtt ttgttgaaga caactgggag aacccatcga tggggtgtgc cggtgtgggt
    52801 tgggaagtat ggcttgatgg gatggagatc acacaattca cgtacttcca gcaagtcgga
    52861 ggactacctt gtaaaccagt tacttctgag atcacttatg gactagaacg tcttgcttca
    52921 tatattcaag aagttgaaag tgtctatgat ctggaatggg ctgatggtgt gaaatatggc
    52981 gagatcttca aacaaccaga atatgaacat tccaaatatt cttttgaagt aagtgaccaa
    53041 gacttgctac taagcaactt tgaccgtttt gaaaaagaag ctaaacgctg tatcgatgaa
    53101 aatcttgttc atccagcgta tgattatatt ttgaaatgca gccatacatt caatttatta
    53161 gatgctcgcg gtgcagtatc cgtaacagaa cgagcaggtt atctttcccg tatccgcaac
    53221 atggctcgtg ctgtagccaa aatctttgtg gcagaacgcg aaaaattagg attcccttta
    53281 ttgaataaaa acacagcaaa tccagaaaac atgaaggagg ctgaataaga tggcaaaaga
    53341 cttattactt gaaatcgggc tggaagaaat gcctgctcat gttgtcacac caagcatgaa
    53401 acaattagaa gaaaaaacag caaaattttt agatgaaaac caattgactt atgatacgat
    53461 cgaaacgttt tctacaccgc gccgcttagc aatcaaagta acaaacattc cagaacgtca
    53521 agcagacagt gaagaagaag tcaaaggacc agccaaaaaa attgctttgg acgcagatgg
    53581 aaactggacg aaagcagctg aaggatttgt ccgcggacaa ggtctgacga cagatgctat
    53641 cacttttaga gaattaaaag gcgtggaata tgtctatgta acgaaataca ctcacggcaa
    53701 agaagcgaaa gaagtattga caggtttagc agatgtcatt aaaagcctca ctttcccagt
    53761 aacgatgcat tgggcagaat acgattttga atatatccgc cctattcact ggatcgtggc
    53821 attgttagat gacgaagtaa tcccgtttga gatcttagat gtcaaaacag gcagagcctc
    53881 tcgaggacat cgtttcttag gcgaagatgt gacatttgcg catgcaaaag aatatgaaga
    53941 aaaattgaat gaacaattcg ttattgcttc accgcaaaaa agacaagaaa tgatcgttac
    54001 acaagcaaat gaattagccg aaaaaaatca ctgggttatt gatctagacg aagatttact
    54061 agaagaagtc aacaatttag tcgaatatcc aactgtcttt tctggcgact tcgaagaaaa
    54121 atatctttct gttcctgaag aagtactagt cacttctatg aaagaacatc aacgttattt
    54181 cgaggtacgg aacgatcaag gtatgctgct tcctcatttt atttctgctc gtaatggtga
    54241 tcgggtaaaa ttggaaaatg tggttcgagg caatcaaaaa gtattgacgg ctcgtttaga
    54301 agatgcggaa ttcttttata atgaagacaa gaaagcttca atcgaccaat acgttgaaaa
    54361 actaaaaact gttactttcc atgaaaaaat cggtagtatc tatgagaaaa tgcagcgggt
    54421 acaagtcatt gcccgtatca ttggcgaaca agtaggacta tctgaggaag aattgatgga
    54481 tctgcaacga gctgctgaaa tctataaatt tgatctagta accaacatgg taggggaatt
    54541 tcctgaacta caagggatca tgggcgaaaa atatgctctg ctgaaaggcg agaaacctgc
    54601 tgtagcaaca gcgattcgtg agcattacat gcctatatcc agtgaaggag agctacctca
    54661 gtctacagta ggttctgttt tagcgattgc agataaatta gatagcattt tttctttctt
    54721 tgcagttggg atgattccaa gcgggtcaaa cgatccttat gccttacgtc gccaagcata
    54781 cggtgtcgtt cggatcatcg aatcgaaaaa atgggccttt cctttgtctg ttctgcaaga
    54841 aacgattagt gatgttatca gtaaagatac ggatcgtttc ggcattggtt tatcagaagg
    54901 gcaacaacag gtgatcgact ttatcaaagg ccgtctgcgc caattattga caacgaagaa
    54961 tattcgtcat gatgtcatcg aagctgtttt gaatgcagaa caaaaagatc tgacaaaagt
    55021 atttgcagca gcacaattgt tcaagcagca tcttgcagat gaagacttca aaccatcgat
    55081 ggaagctttg acacgtgtcg tgaacttagc gaaaaaagcg gagcttgaaa aacaatcaga
    55141 agtagaccct gaactgttcg aaaatgaagc ggagaaagaa ctgcacaaag cagtagaggc
    55201 aatgaaaaaa agctttgctg accaaacgat caacgaaaat tatgatcagc ttgtaagcct
    55261 tcgcccactg atcgaaaatt attttgatca gacgatggtc atggcagaag aaccagcagt
    55321 acgtaagaac cgattaacgc aattaagtca aattgctgcc atggctttgt cgctagcaag
    55381 tttagatcaa atcatcacaa aataatttct aatatgtaaa taaaccagag aataggcaca
    55441 aaataggcta tttctctggt ttatttgtta taaatataaa taactatacc cgtggtgcta
    55501 gttaattttt tcctaggtat tatacaagta atttgagtcg gtcaatttca actgaattat
    55561 ctaaactaac tgatctactt ttagataatt cagttgaaat ttattggtaa actgtcgctt
    55621 ttctttttaa atggcaaaaa tttttaataa tatatgacaa tttagaaatc aactataaga
    55681 ctgattaatt caaaatgatc ttagaatcat tgtatgaaca ctaaatacta tattgttttc
    55741 tattaatcgt tatataaacg attatgaatt caaagctact ttttatgacg tcaatcagag
    55801 agtgtaaaa
//
LOCUS       DAFENC010000015        55495 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.015, whole genome shotgun sequence.
ACCESSION   DAFENC010000015
VERSION     DAFENC010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 55495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55495
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.015"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            548..3187
                     /locus_tag="LP493_001184"
     CDS             548..3187
                     /locus_tag="LP493_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBL2133346.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(3355..4053)
                     /locus_tag="LP493_001185"
     CDS             complement(3355..4053)
                     /locus_tag="LP493_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBL2133347.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            4271..5416
                     /gene="tgt"
                     /locus_tag="LP493_001186"
     CDS             4271..5416
                     /gene="tgt"
                     /locus_tag="LP493_001186"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HBL2133348.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            5513..5893
                     /gene="yajC"
                     /locus_tag="LP493_001187"
     CDS             5513..5893
                     /gene="yajC"
                     /locus_tag="LP493_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HBL2133349.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            6198..8795
                     /gene="adhE"
                     /locus_tag="LP493_001188"
                     /gene_synonym="adhC"
     CDS             6198..8795
                     /gene="adhE"
                     /locus_tag="LP493_001188"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBL2133350.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            9024..10130
                     /locus_tag="LP493_001189"
     CDS             9024..10130
                     /locus_tag="LP493_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBL2133351.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            10147..11175
                     /locus_tag="LP493_001190"
     CDS             10147..11175
                     /locus_tag="LP493_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HBL2133352.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLEGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            11181..11660
                     /locus_tag="LP493_001191"
     CDS             11181..11660
                     /locus_tag="LP493_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HBL2133353.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            11676..12971
                     /locus_tag="LP493_001192"
     CDS             11676..12971
                     /locus_tag="LP493_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HBL2133354.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            12982..13806
                     /locus_tag="LP493_001193"
     CDS             12982..13806
                     /locus_tag="LP493_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBL2133355.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPETP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            13971..14870
                     /locus_tag="LP493_001194"
     CDS             13971..14870
                     /locus_tag="LP493_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2133356.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(14996..15865)
                     /locus_tag="LP493_001195"
     CDS             complement(14996..15865)
                     /locus_tag="LP493_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HBL2133357.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            16018..17478
                     /gene="rhaB"
                     /locus_tag="LP493_001196"
     CDS             16018..17478
                     /gene="rhaB"
                     /locus_tag="LP493_001196"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HBL2133358.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            17475..18731
                     /gene="rhaA"
                     /locus_tag="LP493_001197"
     CDS             17475..18731
                     /gene="rhaA"
                     /locus_tag="LP493_001197"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HBL2133359.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            18745..19590
                     /gene="rhaD"
                     /locus_tag="LP493_001198"
     CDS             18745..19590
                     /gene="rhaD"
                     /locus_tag="LP493_001198"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HBL2133360.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            19592..19903
                     /gene="rhaM"
                     /locus_tag="LP493_001199"
     CDS             19592..19903
                     /gene="rhaM"
                     /locus_tag="LP493_001199"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HBL2133361.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            19985..21136
                     /gene="fucO"
                     /locus_tag="LP493_001200"
     CDS             19985..21136
                     /gene="fucO"
                     /locus_tag="LP493_001200"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HBL2133362.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEVSVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            21263..22021
                     /locus_tag="LP493_001201"
     CDS             21263..22021
                     /locus_tag="LP493_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBL2133363.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIQTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            22121..22765
                     /locus_tag="LP493_001202"
     CDS             22121..22765
                     /locus_tag="LP493_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HBL2133364.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            22772..23779
                     /locus_tag="LP493_001203"
     CDS             22772..23779
                     /locus_tag="LP493_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBL2133365.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            23795..24637
                     /gene="kduI"
                     /locus_tag="LP493_001204"
     CDS             23795..24637
                     /gene="kduI"
                     /locus_tag="LP493_001204"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HBL2133366.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            24657..25460
                     /locus_tag="LP493_001205"
     CDS             24657..25460
                     /locus_tag="LP493_001205"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HBL2133367.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(25709..26773)
                     /locus_tag="LP493_001206"
     CDS             complement(25709..26773)
                     /locus_tag="LP493_001206"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HBL2133368.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(26770..27855)
                     /locus_tag="LP493_001207"
     CDS             complement(26770..27855)
                     /locus_tag="LP493_001207"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HBL2133369.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            complement(27868..28845)
                     /gene="mvaD"
                     /locus_tag="LP493_001208"
     CDS             complement(27868..28845)
                     /gene="mvaD"
                     /locus_tag="LP493_001208"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HBL2133370.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            complement(28838..29782)
                     /gene="mvk"
                     /locus_tag="LP493_001209"
     CDS             complement(28838..29782)
                     /gene="mvk"
                     /locus_tag="LP493_001209"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HBL2133371.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            30098..30757
                     /locus_tag="LP493_001210"
     CDS             30098..30757
                     /locus_tag="LP493_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBL2133372.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            30842..31747
                     /locus_tag="LP493_001211"
     CDS             30842..31747
                     /locus_tag="LP493_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBL2133373.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(31749..32381)
                     /locus_tag="LP493_001212"
     CDS             complement(31749..32381)
                     /locus_tag="LP493_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBL2133374.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     misc_feature    32532..32657
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            32701..33225
                     /gene="infC"
                     /locus_tag="LP493_001213"
     CDS             32701..33225
                     /gene="infC"
                     /locus_tag="LP493_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HBL2133375.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            33297..33497
                     /gene="rpmI"
                     /locus_tag="LP493_001214"
     CDS             33297..33497
                     /gene="rpmI"
                     /locus_tag="LP493_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HBL2133376.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            33550..33909
                     /gene="rplT"
                     /locus_tag="LP493_001215"
     CDS             33550..33909
                     /gene="rplT"
                     /locus_tag="LP493_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HBL2133377.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            34161..35498
                     /locus_tag="LP493_001216"
     CDS             34161..35498
                     /locus_tag="LP493_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HBL2133378.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            35546..37675
                     /locus_tag="LP493_001217"
     CDS             35546..37675
                     /locus_tag="LP493_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HBL2133379.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            37650..38339
                     /locus_tag="LP493_001218"
     CDS             37650..38339
                     /locus_tag="LP493_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133380.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(38747..39360)
                     /locus_tag="LP493_001219"
                     /pseudo
     CDS             complement(38747..39360)
                     /locus_tag="LP493_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(39496..39690)
                     /locus_tag="LP493_001220"
     CDS             complement(39496..39690)
                     /locus_tag="LP493_001220"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133381.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(39740..40180)
                     /locus_tag="LP493_001221"
     CDS             complement(39740..40180)
                     /locus_tag="LP493_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HBL2133382.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(40184..41029)
                     /locus_tag="LP493_001222"
     CDS             complement(40184..41029)
                     /locus_tag="LP493_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HBL2133383.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            41178..42596
                     /gene="pepV"
                     /locus_tag="LP493_001223"
     CDS             41178..42596
                     /gene="pepV"
                     /locus_tag="LP493_001223"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HBL2133384.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(42653..43600)
                     /locus_tag="LP493_001224"
     CDS             complement(42653..43600)
                     /locus_tag="LP493_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL2133385.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(43823..44173)
                     /locus_tag="LP493_001225"
     CDS             complement(43823..44173)
                     /locus_tag="LP493_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBL2133386.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            44373..45452
                     /gene="pepA"
                     /locus_tag="LP493_001226"
     CDS             44373..45452
                     /gene="pepA"
                     /locus_tag="LP493_001226"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HBL2133387.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            45596..45916
                     /locus_tag="LP493_001227"
     CDS             45596..45916
                     /locus_tag="LP493_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBL2133388.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            45938..46402
                     /locus_tag="LP493_001228"
     CDS             45938..46402
                     /locus_tag="LP493_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBL2133389.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            46607..47212
                     /locus_tag="LP493_001229"
     CDS             46607..47212
                     /locus_tag="LP493_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HBL2133390.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(47251..48540)
                     /locus_tag="LP493_001230"
     CDS             complement(47251..48540)
                     /locus_tag="LP493_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBL2133391.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            48968..49447
                     /gene="rlmH"
                     /locus_tag="LP493_001231"
     CDS             48968..49447
                     /gene="rlmH"
                     /locus_tag="LP493_001231"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBL2133392.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            49532..50041
                     /locus_tag="LP493_001232"
     CDS             49532..50041
                     /locus_tag="LP493_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HBL2133393.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            50141..50791
                     /locus_tag="LP493_001233"
     CDS             50141..50791
                     /locus_tag="LP493_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133394.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNTNHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            51242..52180
                     /locus_tag="LP493_001234"
     CDS             51242..52180
                     /locus_tag="LP493_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBL2133395.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            52193..53245
                     /locus_tag="LP493_001235"
     CDS             52193..53245
                     /locus_tag="LP493_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2133396.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            53511..54146
                     /locus_tag="LP493_001236"
     CDS             53511..54146
                     /locus_tag="LP493_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HBL2133397.1"
                     /translation="MIFLQKYGFYFLLLGVISDLSTPYILGLFYPKLNQMTTVISVFG
                     DVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFIGTSKTLAILAVATVGLYGIGDCIFT
                     GLFSINTNESSWNLSTWIHNIGSGLGYAGFLLFPLLLVLLYRQSGQGTLSHFYLVLTV
                     ISLLIAGLYGLARIPSISQFAFFKQLGFFQRLSFFFNYLPMICLSFFQLRK"
     gene            54337..55128
                     /gene="msrA"
                     /locus_tag="LP493_001237"
     CDS             54337..55128
                     /gene="msrA"
                     /locus_tag="LP493_001237"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBL2133398.1"
                     /translation="MLDVEQMEIDLYNIILNRNTREWERTQFEEAKEDLAKMSIKQVI
                     EKLEVNLRPLALRDNLTPDAMDFYLRITGESASAKAYDYAKHKITSPLYQERAIFAGG
                     CFWCMVEPFETKPGVISVLSGYTGGETKKPNYDQVSGGYTGHVEAVEIIFDTRQITYE
                     ELLEIYWQISDPTDAFGQFQDRGKQYRSILFVVNEKQRQLAEKSREQLIQSNRFSRPI
                     VTEIRQAKTFWPAENHHQQFYQKQPKRYKKIKHSHQLHLFFQRHR"
BASE COUNT        17615 a         9920 c        11892 g        16068 t
ORIGIN      
        1 gctctcgata agctcggctt tcttgtacct cggaaggatt caaataaaca gaaatgattg
       61 taactttcca tcatacatgc aaagcacggt gttgaatttc ttcatgttaa acaaaaattt
      121 tgttttcgtt acatcttcaa catttgaaac atctcttgtt cctattcaat tttcagacgt
      181 ttacgttatt caattgttac gtatcgcatt acttcttgtt tcggatactt cgtgatccaa
      241 acatccatac gcattcacta tttataggtt tgtactctac acgcatgtct gggtgaaacc
      301 tgtacttcta acaactttgt ttgcttacac tgttctatcg agaaattctt ctgtctattt
      361 gatggtatcc tccttcctta catctatata atagcatcct ttggtagcgt ttgcaaatat
      421 aagcacttta aattttacgc tttcttaaca aataatcgat aagcccttta tttgaagtaa
      481 ataaaaaaag gatgttatag taaaataagt accttttttt gtacgaagat tttaaaggag
      541 gaataggatg gaagaataca agcagacaat agaagaagta aagaaggtaa cagaagcaga
      601 tccagatact gggttgtctt cacaagaagt ggatgaacgg cgaaaaaagc agggattgaa
      661 taaattcgat gaggcgccga aagaatcgat gatcaaaaaa ttctttcgaa gcttgtccga
      721 ttttacaacg atcatccttc ttgtagcagc ggtgatttcc ttttataccg catttgctac
      781 agaacatggg gatttatttg aaggactgct gatcatcgct atcgttgtga tcaactcggt
      841 attggcgatt gtccaagaag gaaacgcaga aaaagcactg gaatccttgc aagatatgaa
      901 taaacaaacg gcaactgtca tacgagacgg caaagtgacc actgttgagt cagagcaact
      961 ggtagtgggt gatattcttg ttttagagtc cggtgatgct atttctgccg atgcccgttt
     1021 gatcgaagca tcacaattac gtgtagaaga atcggcgttg actggagaaa gtgaagcagt
     1081 tgaaaaagat gcagcattta ttgctgaaga agatgagtca ttaggtgacc aacttaatat
     1141 ggtatttaaa ggatgtacgg ttgctgcagg tcgtgggaaa gcgatcgtca ctgccattgg
     1201 catggctaca gaaatgggta agatcgcgga tcttttgaac gaaaatacta tgcaaaaaac
     1261 acctttacag gtccgattga atcagctagg caaacgaatc agtatgatcg ctttagcggc
     1321 tgcggcttta gtatttgtga ttggtgaact gcaaggagaa ccactccttg agatgttcat
     1381 gacttcgatt tccttggctg ttgcagctgt accggaaacc ttgactgtta ttgttacgtt
     1441 gacacttgca tacggtgtgc agaagatggc gaggaaacat gcgatcatcc gacagttgcc
     1501 agcagttgaa acgctaggaa ccgctaatgt tatctgctca gacaaaacag gaacgctgac
     1561 acaaaatgaa atgcgcgtcc gccgggtatg gagcaaagaa gatgaagtaa cgaatatcga
     1621 agattcaatg acgaacagcg cgatggaaat attgaaaatg gctgcactat gtacagatgt
     1681 gacggtcgag caagaagatg acgaccttgt tatcaaaggt aatccaacag aagtagccat
     1741 cgtaagggct gttgaagaga attatcatac aaaggcagaa ttagaagaaa aatatccacg
     1801 agtaaacgag cttccttttg attctgaacg aaaaatgatg acaacagttc accaaatggg
     1861 cgaaaaatac atctcaatca ccaaaggagc attcgatgtt cttgctccgc gctttagttc
     1921 aggcgatgta gaacaagcgg cgatcgttaa tgatcgcttt ggtaaacggg cactgagagt
     1981 gattgctgtt ggttatgcta cttatgacga agaaccgcaa gatatttctt ctgaagcact
     2041 ggaaaaagac ttacgtttga ttggtctgat cggaatgatc gatccaccac gtccagaaag
     2101 taaaggagca atcaagcgag cgaaaaaggc tggcatcaaa acagtcatga tcactggaga
     2161 tcatgtggtg actgccagtg ccatagcgaa agaattaggt atcttgaatg atccgtcaga
     2221 agcactttca ggatcagaac tgcatcaatt atcagacgaa gaattagatg cgcgtgtcaa
     2281 agctctctct gtctatgctc gggtaacgcc agaagacaag atccggatcg tcaaatcttg
     2341 gcaacgtacg ggtgcagtcg tagcgatgac tggggatggt gtgaatgatg caccagcgtt
     2401 gaaagcaagt aacgttgggt gtgccatggg gatcacagga acagatgtgg cgcaaagtgc
     2461 cgcagatatg attttgacgg atgacaactt tgcgacgatc gtagacgctg tcagtcaagg
     2521 acgttcggtt tatcagaata ttcgtaaagc tatcaacttt ttgctaagct gtaatatttc
     2581 ggagatcttt attgttttga ttgcgatgct gttaggatgg ggagcaccat ttacagctgt
     2641 gcaactactg tttgtcaatg tagttgctga tggacttcca ggatttgctt taggaagaga
     2701 gccagcggaa cacggcatca tggatcagcc acccattccg aaaaatgaag ggatctttgc
     2761 tcgaggttta ttgcaaaaaa ttgccataaa tgcaggggtc ttcaccatcg taaccttgtt
     2821 tggttattat ttaggtagtt atgtcgatac tatcagccca tgggtagacg caagtcagca
     2881 tgtcggtcaa actgttgcat tcttgatctt agcttattca tcgattctgc atgtgttcaa
     2941 tgtacgcagc agccaatcga tcttcaaagt caatttagcg accaataaag ctttggtaga
     3001 aatggcgtta ctggcattag ctattacaac ggctgttgct ttgctgccat ttacgcaaga
     3061 actattcggc ctagtacaca tcagtttgaa tcactggttc ttggtaggga ttttatctat
     3121 cgtaccaatc gcggtgaatg aactgatcaa gttccatcga ttaccggaag cagaagaaga
     3181 ggaatgatta actgtttcta agttgatttt ctttttactg gaactataca aaaaggaggt
     3241 gtgacatgaa tgttgtcaca cctccttttt gctaatgggc tgaatgtttc ttttactgcc
     3301 tctcgataaa cggtgttctc ctgccacccc ctcggtcaca agtcacactc tcttttaaat
     3361 atcttttggc aattgttcat aaaatgctgc ttttgttgca gaaatgtatg ggctgagcca
     3421 tagataacca ataccagcag ttgctaatgc taagatatgc cagccgataa atgaaagatc
     3481 taaccagaaa agttgtcctt tataaccatc catcaatttt cgacttgcag tgatcgtatc
     3541 cagtacttta ggtgtttgtc ctgtttcttg gacgatatcg tagtaaataa aatagctttg
     3601 agaataagaa tagcttttaa tgattccagg aataactaat agcaaacccc ataatgttgt
     3661 aaagatcgag atcagcacag ctaagctgat cactccgccg ataaacaaac ctttgaatcc
     3721 acgaaatgca tctttgaatg gttcgatctg atctttttgt ccacgtaaaa tatcaagata
     3781 agtccaagaa ataccgctca tgaacaaagc gctaatgatg ctggaaataa ttccgccacc
     3841 gcctcctgaa ctaccgcctc ctgaagttgt cgcttctgag acgctcgctg atccatcata
     3901 tatggtggtg gcaaacaaga taataggaat cataataaga agaatagtag caataccaat
     3961 caatgtaggg attagattta gtaaaacagc ttgtccccaa cgtcctttta gactctcttt
     4021 tgcttggcgt tttaattctg cagaagattg catgattttt ccctcctttt ctttaataac
     4081 accaatatac catgtatcaa aaaatatttc tgtcataatg tttttctttt ttttgttatt
     4141 cataaaaaaa ggataaaaaa aagaatatta aataaagtag aaggaagccg agggaacttg
     4201 caaaaagcac ttgaaacgat tatgatggtg ggagttgtca agatatttta tatagaaagt
     4261 agggaaatga atgacgcaac ctgccattcg ctatcgttta atcaagaaag aaaaacatac
     4321 tggcgcgcgt ttaggggaat tgatcacgcc acacggaact ttccccacac caatgttcat
     4381 gccagtagga acattagcta cagtaaaaac aatgtcccca gaagagttga aagaaatggg
     4441 tgctggcgtt attttaagta atacatatca tttatggcta cgccctggtg aagacttagt
     4501 agaagaagct ggcggactgc ataaatttat gaactgggat caaccgattt taacagattc
     4561 aggcggcttt caagtttttt cattaagtga tatgcggaat atcgaagaag aaggcgtgca
     4621 tttcaaaaat cacttgaacg gttcgcgtat gtttttatca ccagaaaaag caatcaacat
     4681 ccaaaataaa ttgggctctg atatcatgat gagttttgac gaatgtccac cattcgatga
     4741 aagttacgac tacgtgaaaa aatcagtaga acgtacgtct cgatgggcag aacgaggatt
     4801 gaaagctcat gctaatccag accgtcaagg attatttgga atcatccaag gagcagggtt
     4861 tgaagatctt cgtcgtcaaa gcgcgaaaga tctagtcggg atggatttcc ctggttactc
     4921 aatcggcggg ttatctgtcg gggaacctaa atcagaaatg aatcgtgtat tagaattcac
     4981 tacaccgttg atccccgaaa acaaaccacg ttacttgatg ggtgtcggtg ctgctgattc
     5041 attgatcgat ggtgttatcc gtggagtaga catgtttgac tgtgtcttgc ctactcgaat
     5101 cgctcgaaat ggcacatgta tgacttctca aggccgtcta gtagtgaaaa atgcgaaata
     5161 tgcccatgat ttccgtccaa ttgatgagaa atgtgattgt tatacatgta aaaactatac
     5221 acgtgcctat atccgccatt tgatcaaatg tgatgaaaca tttgggattc gtttgacttc
     5281 ttaccacaat ttatacttct tgttgaatct aatgaaacaa gtacgtcaag caatcatgga
     5341 tgataatttg cttgaattta gagaagcctt ttttgaagaa tacgggttca ataaagaaaa
     5401 cgcaaaaagc ttctaaagga aaatctttta aaaattaagt aaaaaactag tgttatcagc
     5461 atttttctgc taaagtgttt tttgtagata cagaattagt gaggtgaaaa aaatgggaac
     5521 attaccaatg cttgtgatgt ttatcgcgct attagcaatg tggtttttta tgtcacgttc
     5581 gcaaaagaaa caacagcaag aacgtcaaaa cttgttagat agcatgaaac caggtgattc
     5641 agtcgtaacg atcggcggat tacatggagt tgtttcagaa atcgacaatg acaaacggac
     5701 agttgtttta gactgcgaag ggatcttcct tgagtacgat cgtgcagcaa tcaaaacggt
     5761 caaaccaggg actgtcgtaa caaatgatgc aacgactact gttgaaacaa cagaagaacc
     5821 agctgagaca gttgaagtaa aaactgaaac aacagaaacg ctggaagaga cagaagagaa
     5881 ggaagaaaaa taagtatcaa agcttattta aagacgaggt agggcagaaa gatgtcctac
     5941 ctcatttttt attcaaaaaa gaaagagata agagcatggg atatattgct caatattgaa
     6001 taatcgggtg tgtcatataa ataataataa ataactttat atatttttct atacaaacac
     6061 ctgtaaataa agcaatttta tatttaaaaa taactgtgaa aaaaatcaca aaaaagtgtt
     6121 tacatagaaa aataaatatt gtatgatata catgtgaatt atttaacaaa taaccatgac
     6181 ccattaggag gataatgatg gctaaagtaa tagaaaaaga aaaaacgaag acaattgacg
     6241 tacaagcaat gattgatgat ttggcagaaa aagcaaatgc agcattgaaa gaaatggaaa
     6301 gctttgatca agaaaaagta gaccatatcg tgcatgaaat ggcaatggca gctttggatc
     6361 aacatatgcc attagcgaag atggctgtag aggaaacagg ccgcggtgtt tacgaagata
     6421 aagcaatcaa aaatatgtat gcgtccgaat atatttggca taatatcaaa catgataaaa
     6481 cagttggtgt gatcaatgaa gatgtccaaa aagggttgat tgaaattgct gaaccagtcg
     6541 gtgtggtttg cggagtaact ccaacaacga atccgacttc cacaacgatt ttcaaatcaa
     6601 tgatcgcgtt gaaaacaaga aatccaatcg tttttgcttt ccatccaagt gcccaaaaat
     6661 cttctgcaga agcagcacga gtggtacgtg atgctgctat cgctgccgga gctcctgaaa
     6721 attgtatcca atggatcgaa catccttcga tcgaagcgac ttctatgcta atgaaccatc
     6781 caggtatcgc gatcgtctta gcgacaggtg gagctggaat ggtcaagtct gcttactcta
     6841 caggaaaacc agctttaggt gtaggtccag gtaacgtacc agcttatatt gaaaaaacag
     6901 caaaaattaa acgtgcagtg aacgatttga tcgtttcgaa aacatttgat aatggaatga
     6961 tttgtgcttc tgaacaagct gtgatcgtgg ataaagaaat ctatgcagca gtaaaagcag
     7021 aattccaagc acaccaagtt tatatcgtaa aaccagatga attgcaaaaa ttagaagatg
     7081 cagtgatgaa cgaaggaaaa tatgcggtca atccatcaat cgttggacat tctgcgatgg
     7141 aaatcgcaaa attggcagga atcagtgtac caaaaggaac gaaaatgctg attgctgaat
     7201 tggaaggcgt aggcccagat tatccgctat caagagaaaa actttctcca gttcttgcca
     7261 tgatcaaagc taacaacacg gaccatgcgt ttgatttgtg tgaaggtatg ttgaatcttg
     7321 gaggattagg acatacagca gttatccatt cagaaaacga agagttgcat gtcaaattcg
     7381 gtcttcgaat gaaagcttgt cgtattttag tgaatacacc atctgcagaa ggcggcatcg
     7441 gtgatatcta taacgaaatg attccgtcat tgactttggg atgcggttct tatggtaaga
     7501 actctgtttc tcgtaacgtc tctgctgtaa acttaatcaa tgtcaaaact gtagcgaaac
     7561 ggagaaataa catgcaatgg ttcaaattac cgccaaaaat cttctttgaa aagaactctc
     7621 tattgtactt agagaaaatg gaaaacgttg aacgtgtcat gatcgtttgt gaccctggta
     7681 tggtccaatt cggttactgc gatacagttc gtgaagtatt ggcacgacgt aaaaatgatg
     7741 tgaagatcga agtcttctca gatgttgaac cgaacccatc gacaaatacc gtatacgcag
     7801 gaacgaaact gatggcagac ttcaagccag atacagtaat cgctcttgga ggcggttctg
     7861 caatggacgc agctaaggga atgtggatgt tctatgaaca cccagacaca tctttctttg
     7921 gtgcaaaaca aaaattcttg gatatccgta aacggacata taagatcgac aaaccagaaa
     7981 aaacacaatt cgtatgtatc ccgacaacat cagggactgg ttctgaagta acgccatttg
     8041 cggtcatcac tgacagtgaa acacatgtga aatatccgtt agcagattat gcattgacgc
     8101 cagatgtcgc aatcgtcgat cctcaattcg tcatgtcagt tccagcatct gtcacagcag
     8161 ataccgggat ggatgtgtta acacatgcaa tcgaatccta tgtttcagtc atggcttcag
     8221 attatacacg tggattgagc ctacaagcaa tcaagttagt ctttgactat ttagaaaaat
     8281 cagtaaaaac acctgatatg gaatcacgtg aaaaaatgca caacgcttct acaatggctg
     8341 gtatggcgtt tgctaacgca ttcctaggta tttgtcactc agtcgcacat aaaatcggcg
     8401 gggaatacgg gatccctcat ggacggacaa atgcgattct tttaccgcat attatccgct
     8461 ataatgcaaa agatccacaa aaacatgcga tgttccctaa atatgactat ttccgtgcag
     8521 atacagatta cgcagatatc gcaaaattct taggtctgaa aggcgaaaca acagaggaat
     8581 tagtcgaagc tttagcaacg gctgtttatg aattaggaaa atctgtcggc atcaacatga
     8641 gtctaaaagc tcaaggagtc acacaagaaa cactagatac aaccgtagac cgtatggctg
     8701 aattagctta cgaagaccaa tgtacgacag ctaatccgaa agaaccattg atctctgaat
     8761 tgaaacagat catcattgat gcttacaacg gataagcaaa agaaagcgta gaaaaaagat
     8821 aagaaaatag atgaaaaaga acttggaaaa cgttgtttct ccaagttctt tttttaattt
     8881 ccaagtaact gaaagttact tttgttattt aacatttagg tcaattttag acagtttttg
     8941 ttcaaaaagc gatatttata gtggacggta ttactgctat attaaggata taaaatgaaa
     9001 gcgtttaaaa aggtggcgta aagatgatta ttaaagaaga gatttttgta cctaaagaat
     9061 tagtgaaaga aaaaattgac ctgctcgttg aaaacctgac aacgatcaaa gacgataatg
     9121 gtgaattttt gttggacttt gatggactga aagtagatga caaaagctgg acagtgtgga
     9181 attggccaca aggtgtcggt ctatatggta tttataaaaa ttaccagatg acaaaaaatc
     9241 ctcgcgctta tcaagtggtc aatgaatggt ttgaggatcg tatggaagaa ggcgctccgc
     9301 ccaaaaacgt caatacaatg gcaccgctat tgactatggc ttacttgtat gaagacacga
     9361 aagattcacg ctatttgcct tatttagaac aatgggcaga atgggtcatg aatgacatgc
     9421 ctcggacaaa tgaagacggg ttacagcatg ccacatatgg accggaaaat aagaatcagt
     9481 tgtgggacga tacattgatg atgacagtgc ttcctttggc aaaaatcggg aaactgttga
     9541 atcgcccaga atatttagaa gaagctcgtt accagtttat gatccatatc aaatacttga
     9601 tggataaacg aacaggattg tggtatcacg gctggacgtt tgaaggaaat cataactatg
     9661 ccgaagcatt ttgggctcgt ggaaactgct ggttgacgat tgctattcca gagatcattg
     9721 aaatcttaga attatcgaaa gaagatgcat tgcgcaaatt attgatcgaa acacttgaag
     9781 cacaagtgcg tgcattaaaa acttatcagt ctgaaagcgg tttatggcat acgttgttgg
     9841 atgatccttc ttcttacgta gaatcttctg caactgcagg atttgcttac ggtattttga
     9901 aagcggtcca taaacgttat ttaccacaag aatataaaga agtcgcttat cgtgctatcc
     9961 aaggattgct tgaacaaatc gatgaaaaag gagaagttca aaacgtttca atcgggacag
    10021 gaatggggga cagtttagat ttttatcgga atatcggaat cacagcaatg ccttatggac
    10081 agtcgttaac ggtgctttgt ttgacagaat tgctcgtctc ttattgttaa aagaaaggaa
    10141 acccatatga aaaaaacatc actgctgttt gcagcaagtt cgcttagcct aggtctgcta
    10201 ggtctaagcg gctgcggaaa taattctagt gtggcaactg tcgcagatgc agatgtaaat
    10261 gagatagtta ccttgcgctt tgcttatgca agcaacagcc agccagtaat tgatgcaatg
    10321 aatgaatttg ggcgtttagt aaaagaaaaa acagatggtt ccgtacagat ccagtatttc
    10381 ccagatggac aactgggtgg agaacgtgaa ctgatcgaat tgacacagtc aggagcagta
    10441 gatttcacaa aagtaagtgc ctcagcgttg gaaagtttct ctaaagatta ttcgattttt
    10501 tcagttcctt atctattcaa tgatgaagaa catttcttta aggtgatgga taatgaagaa
    10561 ataatggagc caatctacca atcgaccaaa aatttaggat ttaccggatt gacctattat
    10621 gattctggtc agcgcagctt ttatatggta gacggtccga tccatacgcc ggaagatttg
    10681 gagggaaaga agatccgtgt gatgcaaagc gaaaccgcta tcaaaatggt agagctttta
    10741 ggcggttcgc ccgtacctat gggaagtgat gaagtgtaca cgtctcttca atccaatttg
    10801 atcaacggat cagaaaacaa tgaatttgtc ttgtatacag ctggacatgg tggtgtggct
    10861 aaatactatt cctatgatga gcatacacgt gtgccagata tcatcatcat gaatgatgcc
    10921 atcaaagaac agctaactga tgagcaggaa aaagccattg aagaagcagc gaaagaatca
    10981 acggtttttg aaattgaagc ttttgcaaaa gcaattgaag aagaaaaagc tttagcacaa
    11041 gaagaacatg gagtccaatt caatgatgta gataatacac cgtttcgaga ggcagttgcc
    11101 ccacttcatg atatattcaa aaacgatcct acctacaaag acctttatca aaagatccaa
    11161 gagcaaggag cgtagctgtg atgaaaatga ttttaaacaa ggtattagag atcctgggag
    11221 ctgttttgct tgttgggatg gtcgctgttg ttttatggca agtattttcc agaacggttt
    11281 taggaaatcc aaatacggtc acggaagagc ttgttcgatt cggtcttgtc tggtttgcca
    11341 tgttgtcttc cgcgtatgtt gtgggacaaa aagcacattt agccgtaacg gttttaagtg
    11401 aaaaattaac tggcaaaaaa agtaaaattt tagaagttgt tgttcaaagt ttatttctgg
    11461 tatttgctgc gatgatcatg gtgtatggcg gatggaatgc tgtcacattg acaatggggc
    11521 agatctcgcc ttctttaagt attcctatgg gatatgttta tctgtcagta cctgtatcgg
    11581 gggtactcat cattatctat agcctgatca atctaatcga tacattaagc aacaagccag
    11641 caattcaaga aaaaatataa aaatggagga ataaaatggc aatagaagcc ggattagtgt
    11701 tattttttgt atttgttgtg ttgcttgtat tagggatgcc gattgctata agtattgcat
    11761 tctcatcgat gatgacttta ttgttagtta taccgtttga tgtttctgct tttagttcag
    11821 ctcaaaaaat ggtgggaagt atcaatagtt tttcgctgat cgctattccg tttttcgttc
    11881 tctcgggcat tatcatgaat aatggaggga tagctaagaa actagtggat tttgcgatgt
    11941 tgttcgtcgg gcgcgtgccg ggggctttgg ctcatacgaa tgtgttaggg aatgctttat
    12001 ttggttccat ctctagctcg gccattgccg cttctaccgc gattggcgga gtgttgatcc
    12061 ctcagcaagt ggaagaagga tatgaccgga agtttgcgac agcggtcaat atcgcgtcag
    12121 ctccgacagg tatggtcatt cctccaagta ctgcttttat catgtattca cttgttgctg
    12181 gtggtgcttc gatctctgct ttgtttatgg gaggttatct cgtaggcgct ttgtgggcgc
    12241 taggaatcat gctagtagca ttcatcgttg ctaaaaagaa taaataccct gttgtcgaaa
    12301 aaggacagat ggctcatgct ggaaaaataa taaaagaggc gattcctagc cttctattga
    12361 ttgtcatcat tatcggtggt atcttgacgg ggatatttac agcagtagaa gcttcagcga
    12421 tagctgtcat ttactccctg ttgattgcta tgttttacta taaaacggta aaactaaaag
    12481 atatacctaa tatgttgttt caatcagtag caatgtcagg gacgatcatg ttcttattgg
    12541 ctacttcttc catgatgtct ttcgccatgg cgtttaccgg tattcctcag gcaattagtt
    12601 cgttgattat gggcgtaacg gataataaat ttattattct gttattagtc aatcttgtgt
    12661 tattactggt gggtatgttt atggatgtgg cgcctgctat cttgattttt acaccaatat
    12721 ttttaccaat cgtcacaagt gtaggggttg atcctgtaca ttacgggttg ttttcaatca
    12781 tgaatctgtg tgtaggctcc atcacgccgc cagtaggtac aggactatat gtcggtgcaa
    12841 gtgtaggagg cgtaaaagca gaggcaatgc tgaaaccgct tcttcctttt tatggggtta
    12901 tcttagtcgt cttgtttttg attacttact tcccgcaaat cgtcatgtgg ctacccaata
    12961 tgctgagtta ggagaatagt tatgttgaac attacaatta gaggacatga tctttccgaa
    13021 gtccaaacga tagaagatct tgcagaaaaa acaaaagaac aagggattca tacactgcag
    13081 ctcgccttag gtctttcgtt tcctgaaaca ccttctggcg caaatgagat caattctggg
    13141 atgggaaatt atgtcaaacg agttttagaa aagcaagaag tgaccgtagg aattttaagt
    13201 tgctatatca atatgattca tccagattta acgatacgac aagagttgct gacaaagttc
    13261 gagcagtatc ttcgctatgc ttcttccttt ggtgcgtcga tggttgcttc ggaaactgga
    13321 tgtgttttgc cggaaatcca atatacggaa gaaaatttca cagatgaagc atttgctgaa
    13381 gctgtgtccg ttatccgtcg cttggtaaaa gctggagaaa aataccaaat gatggtgggg
    13441 atagaaccag gtttgaatca tccggtgtat tctttagcaa gggtagagca gctgatccaa
    13501 gcagtagatt cggactatct aggaatcatt ttagatccga ccaatttgat cacaagtagt
    13561 gattatcaag aacaagtcca attggtagaa gaagcttttg aacgttttgg tgaaaagata
    13621 tgtgcggttc atttgaaaga ttttcgtgtc gaacaggaaa aaatcgtgcc ggtaaatttg
    13681 ggagacggtg tgatcgagta cacaaaaatc aaagaaatca tcatgaagaa tcgtccgtac
    13741 ctgtatgtgg ttcttgaaga aacaaaagat gatgggattc gttatggaag aagtcttctt
    13801 gaataatgta aagaagacgt tggttaacta atatttagaa tggagggggc ggggctagaa
    13861 gatgccacgt ctcttctttt ttataagagt atataaaagc agctcttttt gattacaaaa
    13921 aacgtggtat aataaaattg tgcataagtg aacaaaagga ggtgcggcac atgctccaaa
    13981 agaaaatcag cggtgaacaa gtcaatacga tggtttctga tcagtatgaa atctatcatg
    14041 tcaaagatgt cgtcagccaa aataaaacga tctatcatca tcatgatttc tatgagatcc
    14101 atgctacatt aaagggagaa gcgacttttt atttgaacgg acgacaattt acgatcaaag
    14161 caggaagtgt gctgctcatc cattccaatg atttgcatcg tatcgtccgc caatcttcag
    14221 atgtattcga gcgtgtctat atctttgtca ccccttcttt tctagaaagt cgttccacgc
    14281 catggtctaa tctatcggct tgttttcaac caatgggaga gaagaggagt cgtgtattgc
    14341 aaatagaaca ggaagtattg aagcaaaaat tatcatttat cgaccatcct cctgataaaa
    14401 aaatttacgg tgaagacata aaatatgaac aagctctggt agaatacttg atttttctca
    14461 atcaagttgt acaaaaagaa gagagtgcgc aagaacagaa tgctgtagtt cctaatgagc
    14521 gtgtggaaca aatgttacaa tatatctcaa aaaatttatc tcatccgctt tctttagagg
    14581 aaatggaaaa gcagtttttt gtcagcaaat accatatcac acgagaattt aaaaagtaca
    14641 ctggatttac gtttcatcag tatgtaatga agaaaaagct gatctatgcc aagcacttgt
    14701 tgcgagaata ccgcagctct agtgctgtat atagtaaaag tggtttttct tcttatccgc
    14761 attttctgaa agcattcaag agagagttcg gcataacgcc taaagaattt ttgaaacgtg
    14821 atacacagaa acagttggtt cattatgaac attttgaaga tgaacaatga gaatgatcac
    14881 taaaaaataa ccgcagtagc tgctgttgtt tacatagaag cagaaactgc ggttatttta
    14941 tttttatcta tatatttcaa aatattttga aaaaatgacg tacatattat atgaatcagc
    15001 tgaatttacg aaagtctctc ggcgatagtc ctgtttttgc tttgaacagg cggctaaagt
    15061 aagcaaaatt ctcaatccct atttcttcgg aaatcattcg aaccgtaaat tctgtatacc
    15121 gaagaaggtc tttagcgtaa gaaagttttt tgctgatcaa ataatcgatt ggtggagaac
    15181 cgataaattt ggaaaaatct ttgctcagct gatatttatt caataagaat tgttgttcta
    15241 attgatcaag tgtaatcgtt tctttgaaat gttcgtctaa gtattgcttc agtttgtaaa
    15301 cgtaggcggg aatatcctct tcttcgaaat ctagctgata cttttgcaaa atcagttcat
    15361 tcagcaactc gtggatagct acagaggact ggaaatcggt acgggcattc gtgccttgtt
    15421 gcatgtggat caattctgtg atcaaatggt ggatcttgtt ttctgatgga tcccctgttg
    15481 aatggaaggt gttatggccg tcttttgtga actcctgata aaatgattgg acgttctgac
    15541 cattcaaatg gatccaatcc atttcccatg gttcttcgct gatcgtttga taacgctgat
    15601 attcttggca gtcaataaaa aataagtctc cagcttttag ctgttgctga ttatcattat
    15661 atgtaagcga acctttgcca gacaaagtaa actttatcaa gtaagaaggt aaatgtgctc
    15721 gttcagtata gtaagggatt ggtgctttga agtaaccgat ttcttggata taaaaaaata
    15781 aattcctgct tctttgtgta ggcgtcaaga tcactctttt tgagtcttcc gaccatgagt
    15841 ggttggcttt ttcccagtaa tccatgtaaa cactcccaac ttgtcaagat aatgcaatta
    15901 tataccaaaa tagtgtgaag caaaatataa gattctgtat tatgatagca ttgttaataa
    15961 atgataacgc tttattaata aagtgctaat caacaataaa gtaaaagagg tggagaaatg
    16021 aatccaacat ttgttgccat cgatatcggt gcatcaagcg gacgactaat gaaaagtacg
    16081 agggatgcaa aaggttcttt gatcttggaa gaagtacacc ggttcaaaaa cggctttcgg
    16141 aacaaagacg gtcacgatcg ctggaagatc gattatctta tcaaagagat tttgattgga
    16201 tttgaaaaat taaagcagac agggattgat cgcctttttg cggggatcga tacatgggca
    16261 gtcgattact gtctgattga tgaacaaggg gatcggataa atgatccgat tgcttatcgg
    16321 gacaagcgta ccaatggagc agtagaacag ttttctgaaa tctattctct agataagttg
    16381 tatgagcaga cagggattca gatccagcct ttcaatacct tgttccaatt gtttgctgaa
    16441 gaaaaagaaa atttggcaaa agcacataaa ttgttactga tacctgatta tttagggtat
    16501 gtctttactg gtaacatggt gacggagaaa actaatgcat ctactatgca gctgctgaat
    16561 gcagggacaa aagaatggga aatagaactt cttgaaaaaa tcggtgtctc gaaggaatta
    16621 tttccaccat tgacagagcc gggaacgata ctaggagatc tgcaaaaaga acaattttca
    16681 aaatatgatt tgccagatgt gacctttatc acagtagcaa gtcatgatac ggcgtcagct
    16741 gtattaggaa cgccaggtca aggagaacgt tggggttata tcagcagtgg gacatggtcg
    16801 cttttaggga ttgaaacaaa gatcgccaat gtttctcgca atgctttttc tgaaaattat
    16861 acgaatgaat ggggtgccca taacacggtg cgttttttga aaaacatcat ggggatgtgg
    16921 ttgatccagg aagttgcccg aatgcaagag tacgagtaca gttatgcgga attggcagag
    16981 cttgctgcaa aagaaaaacc gctgcagcaa gtgatggaaa tcaatgaccc tcgatttttg
    17041 aatcccccaa atatgataga agagattcag caatactgtt ttgaaacaga gcagccagtc
    17101 cctgtctcat cgggagctat cgctcgttgt gtgtatgata atcttgctct ttgttacgca
    17161 caagagctga tcaaagtaga acacttaact ggaacgaaat tggaaaagct gcacatcgta
    17221 gggggcggat cgaataatcg tctactgaat caattgacag cagattatgc cggaatcatt
    17281 gtagaagcag gacctagtga agccacagca atcgggaatg ttgccatgca aatgctcagt
    17341 acaggtcagt tttcgaatat agaacaagca agaaatgtaa tcaaacagtc gtttccatgt
    17401 gaaacttttt acccagatga aaataagcaa aacacgatgg aatggtacgt gaataaaatc
    17461 aaaggagtaa tcgtatgaac acgattgaaa gaaattacga acaagcaaaa gaaaaatatg
    17521 caactatcgg tgtagataca gatgctgtac tagaaaagat acaggacatc aaaatttcta
    17581 tgcattgctg gcaaggagat gatgtcaaag gtttcttgac accggatggc gaattgaccg
    17641 gtggaatcat ggcgacaggg aattttccag gagccgcacg aacacctgaa gagcttagac
    17701 aagatctgga gaaggcttat tcgttgatac cgggcaaaca caaattgaac cttcatgcta
    17761 tctatttgga tacagaagaa tctgtcgatc taaatgaaat tgagccgaaa cattttgaaa
    17821 aatgggtaga gtgggcaaaa aaagaagaaa tcggtcttga cttcaatccg actttctttt
    17881 cgcatccaat gatgaaagac ggctttacat tggctcatcc agataaagaa gttcgtgaat
    17941 actggatcga acacgggaaa agaagccgca aaatcgcgga gtactttggg aaagaaactg
    18001 ggcaaacaag tatcaataac ttttgggtac ctgatgggat gaaagataat ccgattgatc
    18061 gttttacccc acgggaacgt ttaatggaat cactcgatga aatttttaca gaagagttag
    18121 atgaacggta tgtacaagat gcagtagaaa gcaaactatt tggtttaggc gctgaagctt
    18181 atacagtcgg ttcccatgaa ttttatatgg gttacgggtt gactcgtgac aaacttgttt
    18241 gtctagatgc tggacatttt catccaacag aagtgatttc caataaatta tcttcattag
    18301 ctttattcag caaaggaatc atgttgcatg tttcccgtcc agtgcgttgg gattcagacc
    18361 atgtggtttt gatggatgat gaattgcagg aaatcgctaa agaattagtc cgtaacgaat
    18421 tgttggaaaa aacaaatatc ggtctggatt tctttgatgc aacgatcaac cgtatcgctg
    18481 cttgggtcat cggtacgaga aatacacaaa aagcactgct gaaagctatg ctggaaccag
    18541 ttgagcgatt gaaagaaatg gagctggctt ttgactttac ttcaagaatg gcttatacgg
    18601 aagaattgaa agatttcccg tatgccgatg tatggaatta tttctgttac aaaaatcaag
    18661 ttccagttgg tttggattgg ctggaagaag tccaggaata tcaaaaagac gtgttggaat
    18721 taagaaaata ggagtgtggc tatattgaaa aaaatagata ttttacaagc gccttatgtg
    18781 aaagaaatga tcgaaacgac gtcgaatctt tatcgcttgg gatgggatga aagaaatggc
    18841 gggaatattt cttatttact aaaagaagaa gagatcacac cgttcttgga tcctgaaaaa
    18901 gtgatccgcc gcatctcgat gatttttgat gccagccgtt tagcaggatg ctattttatt
    18961 gtaactggtt caggaagata ttttaaaaat gtagcgagcg aacctgccga gaatcttgga
    19021 atcgttcgag ttgctgaaga tggcaaaaca ctggaacttt tgtgggggct ggaaaacgaa
    19081 tgccttccta caagcgagtt gccaagtcat ttcatgagtc atatcgcccg tttagaagta
    19141 gacccagata atcggatcgt tatgcattgc catgctagtc atctattagc gatgagtttt
    19201 acgcatgaat tagacgaacg ttcctttagt cgtacgctat ggcaaatgtg tacggaatgc
    19261 ttagttgttt ttccagaagg aatttccatc attccgtgga tggttccggg aacaaatgag
    19321 attggggaag caacagctga aaaaatgaaa gaaactcgat tggttttatg gccacaacat
    19381 ggaatctacg ggtcaggaaa agacatggat gaagtctttg gtttgatcga gacagcagaa
    19441 aaggcagcag aagtctatac gtacgtcaaa gcgcaaggac caatcttgca aacaatcacg
    19501 gacgaaaacc tgtggcattt agcagatgcg tttggtgtca ctccaaaagc aggttatttg
    19561 gaggaagttc atacgaaagc aggtgtctga catggtgaaa aaagcttttt gcatgaaagt
    19621 ttacccagaa aaacaagaag aatacaaaaa aagacatgat gaactttggc cagaaatgcg
    19681 tacagcactt cgtgaacacg gggtcatcga ctattcgatc tatcttgatc cgagtacaag
    19741 tttgttattt ggttacttag tgatcgaaga tgaaaagtta tgggaaaaaa tggcaaatac
    19801 atctatcaat caaaaatggt ggaagtacat ggaagatatc atggagacaa atccagatgc
    19861 ctctccagtc agttgggaat tgatgccagt ctttgaactg tagcaacaag caactgggca
    19921 accggttgct tggggttctt tcgtttttat tgtgaaaaaa aatacaaatt aggaggaata
    19981 gaaaatgagt aatcgaatga ttttaaatga aacatcgtat tttggaaaag gagcgattga
    20041 gtcgatcgtc cctgaatttc agcagcgagg attcggcaaa gcagctgtca ttactgacaa
    20101 aggattgatc gagcacggta tagcaacaaa agtaacagaa cttctagata aagcagcaat
    20161 cgcttatgct ttatacgacg ggatcgtacc taatccaacg atccaaaatg taaaagatgg
    20221 agtggctttt gttaaagagg cagaggcaga ctgtttgatc gcaatcggtg gaggttcgcc
    20281 aatcgatacg gcaaaagcca ttgggattat tttgacgaat ccagagtttt cagacgtcat
    20341 tagtttagaa ggtgttgctg atacgaaaaa tccatgttta cctatattag ctataccaac
    20401 gacttctgga acagcagcag aagtaacgat caactacgtc atcacagatg aagtaaatca
    20461 ccgaaaattt gtttgtgttg atcctcatga tatcccaatc gtcgcgttca tcgacagcga
    20521 tatgatgatg ggaatgccga aaaaattggc tgcatcaaca ggtatggatg ctatgacgca
    20581 tgctattgaa gggtttatca caaaaggcgc ttgggaaatg actgatatgc tgcatttaaa
    20641 agcaatcgaa atcatcggcc attctttgga agtttctgta gatggcgatc aaaatgggcg
    20701 agaaaaaatg gcattaggac agtatattgc gggaatgggc ttctcaaatg tcggtttagg
    20761 actggtacac gggatggctc acccgttaag tgcatggtac aacattcctc atggcgtagc
    20821 gtgtgcagca cttttgccaa ctgtcatgaa atataacaaa gaatatactg gagaaaagta
    20881 ccgtgagatc gctcttgttc tagggattaa aggagcagct gaaatgtctt tagaagatgt
    20941 aagagaagcg gcttgtggtg agatcgatcg gttgagcaaa gcggttggaa tcccagaaac
    21001 catttctgaa ttaggtgtaa aagaagcaga tattccagca attgcagaag atgctttgcg
    21061 agatgtatgc acaccaggaa atccaagaga aacgacagta gaagaaatca ttgctttata
    21121 tcaaagtttg atgtaaaaac gaagcggatc ttcaacatta aattgcctgt aaagagaaat
    21181 ggtagtttat atctggatat ctcttttaaa ttgatggtat ttccgctata atttttctta
    21241 taaagaaata ggagaatatt atatggaaaa taaaaagcct tatggaactg tattgatcaa
    21301 agcctctaaa atactagact atttagcgga aaaccaagat gtctctttgc agacgatcgc
    21361 aaagggtgtg ggaatgacct cttctacagt cttgaaaata ctagatactt tgttgatgat
    21421 cggctacgta aataaaaatt cagagaaaaa ctatcgttta ggtgcaaagc ttattcgcta
    21481 cgcgaataaa aacattgaac aaatcgattt ggtagagttg actttaccgt ttttagaaca
    21541 gctgcagcaa aagatcgatg agactatcca cttaggggta ttggacaaca atgagatctt
    21601 gtacgtgaac aaactagatc caaaacatca aacgatccgc atgtcttcaa aaatcggaat
    21661 cacccgacca ttatacaatt ctgcgatggg caaagccgta ttagcagaat tcagtgaaga
    21721 gcagtacact gattatcttg aaaagcatcc gttgatccct tacacagaat atacgatcac
    21781 caatgcatta cggttgaaaa aggaaatcca aacggtaaaa gaaacccaca tcgcatttga
    21841 cgatgaagaa atcgaacgtg atattttttg tataggagcc tcaatcgtga aaaacgaaca
    21901 aatcattggt gcatttagtg taagtatgcc gaaatatcgt ttaacagatg agacaaaaga
    21961 acaaataatc agtgccctca agcaaacaaa aagcgaaatc gagcaaagaa ttcaaaaata
    22021 atgaaaaaag cgtttgcaat ttttcttttc tgccgtataa tatgggtata gatttccaag
    22081 ttataaaata aaatttctaa ataggaaata ggtggagaag atgaaaaaaa ttgatatttt
    22141 atctcgattg aaaaacgccg gagtgattgc ggtggtacgc ggaaaaagca aagaagaagc
    22201 tttgaatgct tgccacgcaa tcatcaaagg tggtctaact ggtattgagt tgacttttac
    22261 agtccctcaa gcagatcaag taatcaaaga acttttgtca ttctacaaag accaaccaga
    22321 aatagtgatt ggcgcaggca cagtattaga cgctgtcaca gctcgcttgg ctatcttagc
    22381 tggcgcagag tatattgtta gcccttcctt tgatcaagaa acggcagaga tgtgcaatct
    22441 gtatcaaatt ccttacttac caggatgtat gactattacc gagatcaaaa cagcgctgaa
    22501 aagcggggta gatatcgtca aactatttcc tggaagcgct tatggaccaa gtatcatttc
    22561 tgccttcaag gcgccgatgc ctcaagtcaa tatcatgcca actggcggtg tgagtctgga
    22621 caatatgaaa gagtggttcg atgctggtgt cgtaacagtc ggagtaggtg ggaacctttt
    22681 agcacccgca gctacaggag attttgacaa agtaacggaa gtcgcgcaac agtatgcagc
    22741 aaaaatgaaa gaaatcaaga ggtagctgct tatgggaaaa gtagtgacac tcggagaaat
    22801 catgttgcga ttgtccacag agcagggaac ccgtatcgat tcaagtgaac gattcgctgc
    22861 ccattatggc ggaggggaag caaacgtagc aatttcttta gctaattacg gacatgaagc
    22921 gatttttgct acaaaagtac ctgataacgc attgggaaaa gcagtcaaaa agcacttgca
    22981 atgttatgga gtagatacga aacaggtatt atctggtgga tcaagactag gtacttatta
    23041 tatggaaact ggtagtggcg aacgcgccgc ctcagtgatc tatgatcgtg ccggatcaag
    23101 ttttgctgaa atggatcatt tggaatggtc gctagaggag ttattccaag gaatagatat
    23161 atttcatgtt tcaggaatca ccccagcttt gtctaaaaaa tggcaaaaaa tgacgaaaca
    23221 ggtgatagaa gctgcaaaaa aagctggctg cctgatcagc ttcgatatca actatcgtgg
    23281 aaaattatgg acacagcaag aagccagcga agtaatccat cagcttttac ctttagtaga
    23341 tatctgctca gctggaaaaa tggatgctct ttatttgtta ggtatcgaga aagcgccaga
    23401 agcagaagaa caacctctaa tttattatta tcaaaaaatg caggaaaagt tcccgaatat
    23461 tcaggtgttt tattcgacca agcgtaccgt tcattcagca agtgaaaatg aattgaaggg
    23521 gacattgtgg atgaaccatg aatatgtgga atcccaagtc catagaatca ccccaatcgt
    23581 ggatcgagta ggtggcggag atgcttttgc aggtggcgtg ctccatggga ttttatccaa
    23641 tatgtctccg caagaaatca ttgattttgc tacggcagct tctgccttga agcatacgat
    23701 ccatggggac tgcaaccaat ttagtcaaga agaagtcgca caatttttag catgcggctc
    23761 tggaaaaatc attcgataga aggagtagaa gaaaatgcaa gaaatggaaa cacgttatac
    23821 acacagtcca gaagatatcc gtcattattc aacggaacaa ttgagaaaag aatttttagt
    23881 agaaaaggta tttgaaccag ggaaaatcag tttgacttat acgcacaacg atcgaatgat
    23941 ctttggtgga gtgacaccta ctgaaaaaga attagaaatc acattagaca aagaactagg
    24001 tgttgattac ttcttagagc gtcgtgaact aggtgtgatc aatatcggtg gaccaggatt
    24061 catcgagatc gatgggcaaa aagaagaaat gaaaaaacaa gacggatact atatcggaaa
    24121 agaaacacga catgttgtat tttcttctca agatgctgaa aacccagcta aattctatat
    24181 tagttctgtt ccagctcatc ataaatatcc aaatgtaaaa atcagtatcg accaagtaaa
    24241 accaatggag actggtgaag gcctgacact gaatgaacgt aaaatctacc aatacatcca
    24301 tccaaatgta tgcgaaagct gtcaattaca aatgggttat acgattttag aaccaggaag
    24361 cgcttggaat acgatgcctt gtcatacaca tgaacgtcgt atggaagctt atgtctactt
    24421 tgattatgcc aatgaagata cacgtgtgtt ccacatgatg ggcaaaccag atgaaacaaa
    24481 acatttagtt gtagacaatg aacaagccat tatttcgcca agctggtcga tccattcagg
    24541 tgtaggtaca agcaattact cattcatctg ggcaatgtgc ggagaaaata tcacctatac
    24601 agacatggat atggtgcaaa tggatcaatt aaaataagca taagggagag aaaatgatgg
    24661 aatttagtat ggatatgttt cgtttagatg gaaaagtagc attagtcacc ggtgctgtct
    24721 atggtattgg atttgagatt gcacgctctt tagctacagc aggagcaaaa atcgtattta
    24781 ataacttgaa tcaagaatca gttgatgaag gtatagcgca ttataaagaa gcaggcatcg
    24841 atgcaaaagg ttatgtctgc gatgtgaccg atgaagaagc ggttcaagcg atggttcaac
    24901 agatcaaaga agatgtaggt tcagttgata ttctagtcaa caatgcaggg atcatcaaac
    24961 ggacaccgat gatcgaaatg gatgcggcag acttccgcca agtaatcgac gtggatttaa
    25021 atgccccatt catcgtttca aaagcagtta ttccggatat gatcgaaaaa ggcggcggta
    25081 aaatcatcaa tatctgctcc atgatgagtg aattaggacg cgaaacggtc agtgcttatg
    25141 ctgcggcaaa aggcggatta aaaatgctga cgaaaaacat cgcttctgaa tacggtcaat
    25201 acaatatcca atgtaatgga attggaccag gttatattgc tacaccgcaa actgctccat
    25261 tacgcgaaac acaagaaaac ggtgaacgtc atccattcga tcaatttatc gttggacgta
    25321 cgccagcagc acgctggggc gagccaatcg atttggctgg accatctgtc ttcttggctt
    25381 ctagcgcatc tgatttcgtt aacggccatg tcttgtatgt ggacggaggc atacttgcct
    25441 atatcggaaa acaaccttaa aagagcttta gtacactgtt tagtggagag gttgtgaaat
    25501 cagcggattg aacgaatacc gaaggacagc tgattaaaca tcatttattc gaaaaaagag
    25561 gctgggacag aagcatttaa ctccaagaaa taagaaggaa ttcacgaaaa ttgcttttca
    25621 aatttttgtg aatttcagct tatttccgaa ggagttgctt ttacttccgc cgtttgtacg
    25681 tgtttagagc gtgagacaaa agtgttcttt acttttgtcc cacgctcttt tctgtgcgtc
    25741 ttccatactt cactaagtcg atccctcttg cttcgcacca atccttcact ggtccggaaa
    25801 agatcagaga ttgttggtgt agggccgcgg tattcgttgc gccgaccata gtataaagca
    25861 gacgaagctc ttcttgccat tgcttcatca gtataatagt ttcttctacg ccgtgattca
    25921 tcagatgcgt cagtacggtt cctgaagtac ccacggcatt tgcgccgaga caaagggctt
    25981 taaatatgtc ataggcattg cggatacctc cggaggctag gatttccata gaagtgtctg
    26041 cttcatttgc ttcaagcaat gaagagactg tcgattgccc ccagtcagct aaataactca
    26101 gttcccgctt ggagcgacgg gcgttttcga tctgggtgaa gcttgttccg cttcgaccgc
    26161 tgatatcaac tgtatgaact cctaaagcag ctagatcatt gagcgtttct cttgtcatgc
    26221 caaaaccgac ttcttttacg atgaggggga cgtcaatggc tgtttgagtt tcttgaataa
    26281 gtactttcca attggtaaaa tcacggtctc cctcaggcat aaccaactct tgaggtgcat
    26341 tcaaatgaat ctgtaaggca tctgcgtgaa acaatcggat agcttctttg gctctttcga
    26401 cagaagtccc tgcaccgatg ttggcaatga ttttcccgtg aggatattct tgtcgcataa
    26461 tcgtataagt atcggctaaa gaagggactt tcaaggcagc gctgactgaa ccagtggcaa
    26521 tcatcaaatc tgcttctctt gcgacgattg caagatcttg gttgattttt tttgtttttt
    26581 cgcttccgcc agtcatcgca ttgatataaa atgggctgct tagtgtaaac ccaactgcct
    26641 gtgtacttag atcgacatca gaaactgcta tttgcggcaa agggttatgg atgatccgta
    26701 cgaagtcaaa ttcgtttttt tgtttatcat gaaaggcttt agctagtgaa acatgttcgt
    26761 cttttcgatt catcggtttt cctttctttg atcgctatag acatgtaacg gcagtggagt
    26821 gatttctgct ttttcccatg cactcattaa aggaagaatg ccagatttct ggtcaacaat
    26881 tacgattccg caatcgcccc cacctgcacc agaagatttt gcggctcctt catactgttc
    26941 agctaaatta cacaatttgt tcaaagcagg cgtttcgatg acgaccccag tgattgcaga
    27001 taaatcatgc agtaattgtc ggttttttcg aatcatctgt tggatcaacg ttacattatt
    27061 ttctttaaac cctttgatca tttcgttgac acattctgta ctatttttta agaaaagctg
    27121 ataagccacc attttatctt ctctcgaacg gtgaacttga tcgaccaaat cagaagtaga
    27181 ggcagggcta cccgtccaac caatcaataa acgtaaatct tcaggagcaa tcaatggctc
    27241 aatggataga cctggccaat ccagggcaag taactcactg atagaatgct gagtttcttg
    27301 ttcttggagc caaggatggt cgaaggttga gaaagcgatc cagccaccat aacagctagc
    27361 agcgatgtcg ccgcaggaac cattatcttg aactgctaaa ttggctagtg ctgcaatctt
    27421 gaaaatctcc aactgagata aattcaacgc gtaaaaaaca ttcaaggctt tgaccgttgc
    27481 aacggtcacg gcaccgctag aacccaatcc atatttccgg ccatttgaac tgtctaactc
    27541 acttgttact ttcagatcat aaaaggataa aagaatgttt ttttcttgtg catacttttc
    27601 agtcaagcga atagcagcaa ggatataatg aaaaggattt tcccgaatat ctaaaactaa
    27661 ttctccgttg cgtcttgtcc aacgtacagg catcccacta tattgtgcag attggatact
    27721 tccgactttt cgtgcagatt ctacagtgac tgtcacgaat tgatcgactg cagcgataac
    27781 tgctggatgg cctgtttcaa caactgcata ttctccggca atatagagtt tgcctggtgc
    27841 agatacttca atcataaaaa tctcccttta ttcaataatc gcaattcctg gaccagcatg
    27901 tgcagtaatt acttgttctt tgctaaataa tttggtaaat gtttcttgta cctcagataa
    27961 atggctgttt tccactaaaa ctttgacatt agggccagca tccatcgtaa agtagcatgg
    28021 aatgccttgc tttctcaatt gtcgcaccgc atccatcgct tttaagctgt caggagacca
    28081 gtaagtgaat ggaggctggg cagctaaagt cgttccatgc atttttagtc cgtttctttc
    28141 catcgtttct ccgagaagtt ggaaatcttt tgttttgatt gcttgtttca attgatatag
    28201 atccccttca acggaatcta accagccttg ataaaaactg gatgtttcga ctgtccgacg
    28261 catcccattt ctgctggaca cttctttttt ctggtcgttg atcaaaacga aaaccattgc
    28321 taaatcgtct tcgaaagaat cggaagggac tggcttagcg taagaactta agtcgtcatg
    28381 gcctttttcc cattcgacga aaccaccgaa aatacttcgg caagctgaac cagacccgcg
    28441 tcgagcaaat cttgaaagag agagatcatc taatccaagc ttaagagcag tattgcaagc
    28501 gcctgctaaa gcagctagcc cgctggcaga ggaggctaat ccagctgcgg taggaacgaa
    28561 attctgactg attactgaag cttttagtga gaggccggct tctttacgaa aaaggtcaag
    28621 aaactgactg actttttttg ttgctttttc gtcttgcaag gtgccatcta gataaaattc
    28681 atctaccata tagctatcag aaaagatgac ttctgtctct gtataaaatg catccaatgt
    28741 taacgaaagg ctgttgttca ttggaaggat gagttcttca tttttcttac cccaatattt
    28801 gattagagca atgttggtat atgcgcgtgc tttgccttta aacataggta tgtactccta
    28861 atccttgtat ccaagtttca gcagcacccg catcttcaag tgcttgactg atttcttggg
    28921 cttttgtttt tgtttgtgct aatgcaatca tacagccacc gcgtccaccg ccagttaatt
    28981 tggcacccaa tgccccggta tcttttgctg tttggatcaa tagattaaga aaatcattgc
    29041 tgattgtcag cttttccaga agtgattgtg attcatccat tgtctgtgcc aacgtttctg
    29101 gtgaattttc aatgattgct tgttttgctt gcttcgtcaa gtatcctaat ttttggatca
    29161 tttgtccagt ttcatgaggc tgggtttcaa agaggtgagc gacatctttg acggcttctc
    29221 ttgtttgtcc tttgattcct gtatcagcga caatcaaaaa agcatcgatg ttcaaagaaa
    29281 agtagtcgaa aggatgccct tttgtaaaat aaatcggctg caagctgcta gtagcggctg
    29341 catcgattcc actaggatta ccgtgggcga ttttttccga aagctggaca ttttctaata
    29401 gtatttcacg agacaaagga aatgctaagt aatcataaaa agcacgagtg actgctgtgg
    29461 cgactgcagc gcttgatccc attccacgtt cagcaggaat cgtgctttca atggtcagtt
    29521 gcaagttttt ttggatgtca tgctgttttt ttaagtgaat gaataatttt ttgatatttt
    29581 ttaatgcatg aggagcttcg gctaaatttc ctgaatagta ggaagaaacc agttgatcgt
    29641 ccattgcatc cagctcttca aggaatgcgg tgacttttgt tgcatagaaa ggaaaggcaa
    29701 tcgctggttc tccataaaca accgcgtgct cgcccatcaa tatgatcttt ccgcttgatt
    29761 ctccttggcc atagtttgcc ataatctaac tccttctcac gtaaaagtga tttttaagca
    29821 aaaaataaag cgcccaaaac gagttgcgct gcttcacgaa tttttttgtc cactaagggt
    29881 ctcaaaaaac attcctcctt tattttacta aaaccatctc agaagtaaaa ctaagaatac
    29941 gttttctaaa gaaaaaacac ttttttctta agaatttttt gacttttttt cttctttgac
    30001 tagaaaaaaa tacaattgac actactagat attgggggta tatttaaaaa ggttggagtt
    30061 aaacacaata tttagtgatg aagtgagctg gaggtaaatg agcgtgatcg ttttagcagg
    30121 tacaattggt gccggaaaat caagtttaac agaaatgatg gctgaacact ttgatagtca
    30181 ggcattttat gaatcgattg atgataatga agtcttgccc ttattttatg caaaccctga
    30241 acagtatgct tttttgctgc aaatttattt tttgaataaa cgttttgcaa gcatcaaaca
    30301 agcaatgaaa gatgacaata atgtattgga ccgttcgatt tatgaagatt cactgctttt
    30361 ccatctaaat gcagatctag gaagagcaac agaaacagaa gttcgtgtgt atgatgaact
    30421 gctggaaaac atgatggaag aacttcccta tgctgcccat aaaaaacatc cggatttatt
    30481 agttcatatt cgtgtatctt ttgatacgat gttggagcgt atcgaaaaac gtggtcgttc
    30541 gtatgaacaa ttgtcctttg atccaagtct atacgattat tacaaagaat tgaacagacg
    30601 ttacgatcaa tggtatgaag aatacaaaga aagtccaaaa atccaaatcg atggagaccg
    30661 ctataatttt gtggaagatc ctcaagcaaa agaagaagtc ttgaaaatga tcgaagaaaa
    30721 attagcagag attcgccaaa ccaaagtagc catttgattt acagttgctc aaataaaggg
    30781 taaaccttta tttgagcgac ttttttcttt atactggaaa caaatgtcag gaggatagag
    30841 tatgcgggaa aaacactatt ttaatcaaga ccgtaatttt tggatcaatg tacagcaaaa
    30901 cgatgtgcta gctgttaaaa acttaaaaga agaatatggc attagtgacg agatgctgac
    30961 ttattctcta gataaaaatg aacgggcgcg cgtagagtac gattcttttg atgaagcgtt
    31021 actgcttgta tcaaatgttc cgcaccagca aaaagtcgat aatcattatg aaactagtcc
    31081 tatcgctttt attttaaaag aagacggttt gtttacattt accacgccga ataccgagta
    31141 cgtgattcga ctaattcgat cgcttttgga acgaatgcca gacatgagtg tatacagttt
    31201 attgtttcgt acattgtttt tgatttctga ttcctttttt cctttaatcg aggaagtgaa
    31261 tagtgaacgt cagcggctta atctgaaatt aagagaaaaa acaacgaaca agaatctgct
    31321 gcaactttca gatttagaga tcggtttggt ttacttagtt acaggaacaa aacaaaatgt
    31381 agtactttta gaacaaatca aggcattggc tatttatcgc aagttgtcag aaaaggaaaa
    31441 agaagagttg gacgatgcgc tgatcgaagc acgacaagca gttgaaatga cgaacttagc
    31501 ttcgcagatt ttagaccagc tctctggcac ttataataat ttgctgaata acaacttgaa
    31561 tgacacgatg aaatttttga cggtctggtc gctgatcttg accgttccaa ctattgtgac
    31621 aggattcttc ggaatgaatc tccagttacc ctttacccat tccgttttcg gatggggaat
    31681 cgccttgatc atcagtttgg tcttatctat ttggatgctt attgcactgt ggcggcggat
    31741 tcgttgatct agtctttgat ctgcaaacca agggcttggg cgatcacaag tgcttgctct
    31801 tggttgacga ttagtcccgc caaagaatct tgagataaag cgattgctgt gaagaaatta
    31861 gtcgtaaagt ctaatccctt cagagaagtt cgaaaccagt tcgaaccggt caactgattg
    31921 tcagacaaaa aaaggttttt ccaagtgacc tcataaaatt cgctgtcttc taattgacaa
    31981 tgatcgaagg agacagcttt caagtttgta ctactaaagg aagccatcga agcaatacaa
    32041 tcagtgaaag tacagtctcg aagataactt tcggcaaaat tcgtacctgt taatttacat
    32101 tgatgaaaca cgacttggtg gaaactgcca ccaatccact ccagattgga aaaatcacat
    32161 ttttcaaaaa tgacattact gcattcaaaa tgacgtaaaa ctgttttttg catcgtaagt
    32221 ttttggatat gactctctct taataccata tttttggcat cgagatagct ttggtcaccc
    32281 ccgttgatca gaagaccaga gaagatctcc tcatcttcta aataaaactc tccctttgta
    32341 agaagaggaa gagaaggtgg aataggttcg atttttttca tgtgggttca cctcgttttt
    32401 ctttagtata gcaaagaagc gggaatcact gctagaaagt ctgctaatct aatcattttc
    32461 agaaaaggaa gacaaactgt atgaaaaaca ttgacaaaaa gattagtttt tgctatacta
    32521 tgatggttga gaaataaaag cagaagcacc cgcttctcgc cttagttgat aatgtcactg
    32581 ggctagatag ttttcactgg ttctattagg tgaagtacgc gcgggttctg taagagaact
    32641 cgttttttta ttgccgttta ttcggtaagc ttttctttct ctcataatat ttggaggtga
    32701 atgaccatag caaaggatat gatggttaac gacggcattc gtgcacgaga gttacgattg
    32761 atcggttcag atggtgagca attaggagtt aagacaaaag cagaagcatt gaatattgca
    32821 gaacaagcaa acttggatct tgtgttagtt gcccctggtg cgaaaccacc agttgcgcga
    32881 atcatggact acggtaaata ccgtttcgaa caacaaaaga aagaccgcga agcgcgtaaa
    32941 aaacaaaaag tgatcaatgt aaaagaagtt cgcttaagtc ctacgatcga cttgaatgac
    33001 ttcaatacaa aacttcgtaa tgcacgtaag ttcttggaaa agggcgataa agtgaaagct
    33061 tctatccgtt tcaaaggccg tgccattacc cataaagaaa ttggtcaaaa agtcttgaat
    33121 cgcttagctg aagaaactgc ggatattgca acagtggaac aaaaagcgaa aatggacgga
    33181 cgcagcatgt tcttgacgct ggcaccgaaa aacgacagta agtaatttga atgactaact
    33241 ggctgttgga cagccgatag tcggataacg aaagattttg aggaggaaat atagtcatgc
    33301 caaaacaaaa aacacaccgc ggatcagcaa aacgtttcaa acgtactggt aaaggcggat
    33361 tgaaacgctt ccgcgcgttt acaagtcacc gtttccacgg caaaacaaaa aaacaacgcc
    33421 gtcaattgcg taaagcaagc atggtttcta gtggcgactt caaacgtatt cgccaacaac
    33481 tagcaaaaat gaaataagaa gtacaaataa cagaatctga agatttattt ttattaggag
    33541 gaattataca tggcacgtgt taaaggtgga acagtaactc gtaaacgtcg taaaagagtg
    33601 ctaaaattag caaaaggtta ctacggttca aaacacactt tatttaaaac agcaaaagaa
    33661 caagtaatga attcatacaa ctacgcatat cgcgatcgtc gtcaaaagaa acgcgacttc
    33721 cgtaaattgt ggattgctcg tatcaacgca gcagctcgta tgaatggctt gagctactca
    33781 aaattaatgc acggtttgaa agttgctgaa atcgacatca accgtaaaat gttagctgac
    33841 ttggctgtta acgatgcagc agcatttact gcattggctg accaagcaaa agaagctttg
    33901 gctaaataag ctaaacaatt ataaagagga aagaagataa cgaaaagtta tgttctttcc
    33961 tcttttttta tttacaatcc tccatcaaat gaaacaggac aataacgtat aagtctaaaa
    34021 tagcataatt aaggtttttt aattgaaaac tgaacattta tggtcaccct ttaatgaaag
    34081 cgctaactac ataagttaga atgagtttga ctgatatatt agtttgctta tcagaaaaac
    34141 aaaatggacg gaggaataac atgagtgata ttattattgg tattttgtta gttatctcat
    34201 tctttttcat ggtctggtac tgtgtaaaag gctacaactt gatggtcggc tttgccatca
    34261 tggctactgt atggatggga ttagcgctag tcggaaacac gttttcacca aacccggcga
    34321 tggaagggca aggagtaatt gatgtgttga cgcatatcta tacgacgggg ccagctgagt
    34381 acgccaaatc gatcttggta aatgtcttct ttggtgcctt tttcgggcgt gttctagtag
    34441 atagcggaat cgcagctacc ctgattcgaa aggtagttga acttggaggg gacaagccaa
    34501 gaatcacgat gagcttacta tgtattgtaa ccgctgttat attcatgtcg atgacaggaa
    34561 tcggaccagt gatttctatt gcagttattg tgttgccaat cttgatgtca ttaggtattt
    34621 cagtaccggt tgcactgttc tcatttatgg gctcgattat ggctggaatc tttgctaata
    34681 tcgtcaattt caaacaatat caaacgattt atgctggttt caatccagcg gctgaaagct
    34741 atacttataa tgactatttc caaattggta tgattgggat gattgtaagc ttagttgtgg
    34801 tactaacggt cgctaatata tcaatgaaca aaaagaaacg ctatgcaatg gcagcaaacg
    34861 taccagctga aggtggcgac gcaccaatga tctcatggtt agccgtatta ttaccagttt
    34921 taggggtcgt tcttttagat cttccaatca tcttaggttt tattctagca ggtatctggg
    34981 cattgctgtt tactggaaaa ttgcgcggag gttataaaga aatctgtcgt cagtttgcga
    35041 aattatttac agatggcgca gtagatgttg caccaatggt tggtttcttg atgaccttag
    35101 cgatgttcaa taattcagct gcgtatgctt ctccttattt ttcagctatt tttggagatt
    35161 ggataccgca atcaccatta gtcttggcaa tcgtatttgc tatattgaca ccactaggat
    35221 ttttccgcgg tccaatgaat ctagtcggtt caggctcagc tattttagct gtcgtattag
    35281 ctgttaatcc aacgatgtcg ccagcctttt tgttcccgtt atttgcaatc acaacgattg
    35341 ctcctcagca tttagatatt acacaatctt gggttgcttg gggattaggt tatacaaaag
    35401 taacttctcg agaatatatg aagaaatcca tcccaactgg ttggatcatc ggagcgatct
    35461 tatgcctgat cacgttctta ttgtacggga acgcctagta aacaaaacgt cgataaaaac
    35521 gattagatga atggaggaaa agaaaatgaa acgttttgtg cgaatgggaa ttgatgttgg
    35581 cggtacacat acgaaagcag tcgcaatcga taatgcgacg cacgaaatca tcggaaaatc
    35641 ttcagtgaaa acaacccacg atgatgtccg tggagtagcc gcaggtgtcg ttcagtcttt
    35701 tcaaaattgt ttgcgggaaa ataatatcag tccagaagat gttgtgtttg ttgcacattc
    35761 taccacacaa gcgactaatg cactgattga aggagacgta gcaaaagtcg gcgtaatcgg
    35821 gatggcaaaa ggtggattag aaggtttttt agcaaaacga caaactagat tgaacgatat
    35881 cgatttaggg aataagaaaa aaatagagat tgtcaatgca ttcttacctg tcaaacactt
    35941 aaatgtagac cgtgtttcag aaacgatttc ttctttagaa agagaaagag cggaggtctt
    36001 ggtttcttct atggcatttg gagtagataa tggggaacca gaacgagttg tttatgaagc
    36061 agcatcggta aaatcgatcc ctacaacgat ggcttctgac atcacaaaat tatatggatt
    36121 gacaagaaga actcggacag cagcaatcaa tgcatctatt ttaccaaaaa tgctagatac
    36181 ggcaacctct acagaagatt ccgtacgaga agcaggggtc aatgtttctt tgatgattat
    36241 gcgcggagac ggcggagtaa tggaaatcaa tgaaatgaaa aaacgacctg ttttaaccat
    36301 gctttccggt ccagcagcat cagtcatggg ctctttgatg tacttgagag cgtctaatgg
    36361 tgtttatttt gaagtaggcg gaacaacaac caatatcggg gtcattaaaa atggacgtcc
    36421 agcaatcgat tattcaattg taggtggcca cccaacatat atctcttcat tagatgttcg
    36481 ggttctaggt gtggcaggcg gttcgatggt acgggctaat cagtcaggaa tcatcgatgt
    36541 cggtccacgt tctgcacata ttgccggtct agattatgca gtatttacgg agacagaaaa
    36601 aatcaaaggt cctaaggttg aatttttctc tcctaaagaa ggagaccctg ctgattacgt
    36661 caaggtagtg atggaagacg gagaagaagt gactattaca aatacatgtg cagccaatgt
    36721 ccttggatta gtgcaagaag aacatttttc ttatggaaat gtcccatctg cacgaaaagc
    36781 catccaagca ttagctgatt attgtcatac gacggttgaa gacatcgcag aacagatcat
    36841 ggaaaaatcc tatgctaaga ttgaaccggt gattttagaa ttggcagaca agtatcactt
    36901 ggagaaagat cagatttctc ttgtaggtgt agggggcggc gctgcctcat tgattactta
    36961 ctttagtaat aaaatgggtg tgaaatattc gattcctgaa aacgccgaag tgatttcttc
    37021 tattggtgta gcacttgcaa tggtccgaga tgttgtagaa cgtatcatcc cttcgccaag
    37081 taaagaagat atacgatcgt tgaaaaatga agcgatgaat aaagcgattg aatcaggcgc
    37141 tacaccagaa tcgatcgaag tccacgtaga aatcgatcca cagacttcaa aagtaacggc
    37201 tatcgctact ggttctacgg aagtgaaagc aaccgatcta accaaggaga tcacaacaga
    37261 agaagcacta gagcttgctg cagaggatat gcgattaaat aaaaatgaag tttgcttatt
    37321 ggaaaataca cctttctttt atgtatgcgg cgaacagaat cgttcaaaaa atgctggaag
    37381 tcttcggatc atcgatcaaa aaggatttat caaggtccaa cgtggacatg cttcatgtat
    37441 gaaaacaact gcagccaatt atatgacagc tgtcgaacaa ctttgggaag atatggcagt
    37501 ttatcaaact gaattgattg cccgaccaga attttatctc tgcttaggag caagagtctc
    37561 tgattttaca gcgacggatc tggaacaact acagcttttg atggatctgg aagtatctac
    37621 tatggaaccg gaggaagaag tgatcgtcgt tgccggaaat atcaaacaaa cataagttag
    37681 aagagttact aaacgaatta caacagatcc ccgaagaaat ttggggattc taccagtttc
    37741 ggcgagattt attttggaaa aagattcctt tgtccaagca gaaaattctt atacaacaat
    37801 caatcgattg tggtatcgaa acggcatgta gcatcaaaaa aaagtaccct tttgccgatg
    37861 taggagaaat ttgtgaacaa atggctgttc caatcgtttc ctgtgaatca gagcaaataa
    37921 acgaacgaat cacttttgca acttatgcag aagatgaagg gattcgattg atgacggagc
    37981 cgttagaaaa attaaaatgt tcaggactag cttcgatctc taaagaaaca gcgcaagctt
    38041 tgattattgg acatgaacta tttcaccaca tcgaagcttc tgttaaggga atttatacgc
    38101 aaagcgaaaa aattgtgctg tggcggttgc ctttttatac acatcaatca aacattcgtg
    38161 cattgagcga gatagcagcg atgagttttt caaaagagat gaatcaaagc gatttttcgc
    38221 cttatgtatt agaggcagtc ttactttggc catataatga aattcgtagc caagggatct
    38281 tagaagaaat aaaaaaaata gaaaaaagat gtacggagta tgatttagat tacaaataaa
    38341 gagactgtga caaaagtcgt gtcacagtcc tttttttccg aataaacgat gttctcctgt
    38401 caactcctcg gtcacaagtc aaaatattca acaaacatga gaagctgttt tttgaaattg
    38461 ttccttgtga ctcggagatg aacggcaggc tcacgacctc ttggaaaacg gtgttcaaaa
    38521 gcttgcatct gcggtaataa gtccagccaa gttaaaaaca taagaagcta tttttacttg
    38581 gctgttctta ttacttgatg cagggcagct ttttcacaac ctctcaataa acggtgtgca
    38641 atcagctgac cctcggtatt agctcaaaaa aaacggcaaa atatgaggaa ctattttgcc
    38701 gtttctttct ctaatactca ggtcaaaacg ctgattccaa aacctcttat ttgatgggtc
    38761 tgtcctgaat atcttcaaaa taatcggggt aattatgaat cacgtattct tgctcctcga
    38821 taatcatatg taaatgcatc gtgcaaagaa atccgacttc atcaaagtta tgatcaatca
    38881 ttgattgaag cattgtctga tgttcatcta atactcgacc ccagtctaat tctgaaatcg
    38941 tcaaacgtaa ccatctgaaa cggttcaagt gcgtactata actttctagc caatcccaaa
    39001 tttctcgttt tccagcaatt tcataacaag ttcggtgaaa atcagtatcc aaatcaaaaa
    39061 aagctttttt attttgagcg attactgcct gatcggtttt tccaactttt cccgcgtata
    39121 acgggctaat gaagcagatc ggatatcgat ttttgaaaca taagtgccgg actgtggaat
    39181 ggtttttaca agctcttgat tgcgcagttg gatcagtgct tctcgaatcg gtgtacgccc
    39241 gatagctagt tgttcttcta acactttatc ggagatttta cttccaggtg ctaactcgga
    39301 ataaatgatt tgtttacgta tagattcata agcttgctgt tgcaaattat tgataaccat
    39361 ttaaccttcc tttctatgca gatataatct attataacat aaatcgctta caaatcgtgt
    39421 gggcataaaa acacagtctg caaaaaaagc cctgataggc atgcctatta gagcctcgaa
    39481 aagaaaaata ttgaatcaat ctggtcgtac ctcttgtatc ggtttgacac gaccgccgat
    39541 tcttttagca aaagcttcgg attctttttt gtctttgaaa atgagcagat tgtctaagtt
    39601 tttttcccga gtgcgacagc cagttttatc gatgtaaccg tgcattactt taacgacata
    39661 catggggatc acctgctttt ttcttttcat tatacgaact actcgacaca atacaagaaa
    39721 aatgcttaga cggtctttat taagaattta catcatccaa agaagcgtac gcttggaata
    39781 actgatctaa ctccggattg actttgctca gcttcactaa tcgttgcgaa tcagaaagta
    39841 aaaaacagtg tttactactg ccagtagttt ttaatttttt gtcttcagtt cccacaattt
    39901 cgtagctaaa atccaaccgt gtccccgtat acttttggat agttggatgg atgctcactt
    39961 tttctccgta atggatcatt tctttatagc tgcaatttac ttccagaacg gggatgatga
    40021 tcccagattc ttcgattttt ttatagggaa accctagatg taccaataag gctacccgag
    40081 cctcttcaaa ccagcggata taattgctgt gatgaataat ccccatttga tctgtttcat
    40141 aataaaaagg ttctcgcaca taacctgtaa atttctccat gactcatgcc tcgttttcca
    40201 ttgatttttt acaaaaataa ttcatccatt tcggaagtgc ttcgctgatt tgtgtcggca
    40261 aaacaatata ttgttctttt gccagctggt ctccaatgaa actatgaaga taaatagctg
    40321 ctgcaatcgt ttggtcattt tgaggaaact gggctaaaaa tcctgtgatc atcccagcta
    40381 aagtgtcacc catgccgccc gttgccatag cagcagaacc taaaggattg gtgtagaagt
    40441 gctggtgacc ataaattttt gtctcatgac ttttcaaaac gagcacagca ccgatttcct
    40501 gttgcttctt tttgttttct ttatcccgtt gttcttgtat cggtagagaa ctcaaccgtt
    40561 gccactccat ttgatgaggt gtaagtacag tttgttcggg atagggtagc aaaagatgat
    40621 tagcagcaag taaacttaaa gcagagccat caatcaccag ccattgttct tttgattggt
    40681 tttctagtac ttgtttgaaa cgttccaaac tcttagaaga agtacccaat ccgggaccaa
    40741 tcaagagtac atctgcttgc tttattacgg aaagaaactg gtcagtatcc gtccaaacta
    40801 caatcattgc ttctggcaga tgactgtgaa gagcactccg atttttttca tcagttacta
    40861 cagtcgtgag acccgctccg ctgtgtacgg cagctaaagc actcataatg attgctccgc
    40921 catattgttc attgccgcca atcaaaacga tacgtccaaa tgttccttta tgtgaaattt
    40981 ttggacgagg tgtgatgact cttttcacta gttgttcgtt tatcagcatc taaaaacctc
    41041 cttttactca ttatagcgta tatttttttt agagaaaaac agataagaaa aggaattgtc
    41101 agattttttg aactattttt ttctgtaatt tgtggtatca tgaacacgaa gacttaaata
    41161 agtggaggat taactttatg acaattgatt ggcaaaaaga agtagaagca cgtaaagaag
    41221 acttgcttga agacttgaaa aatcttttac gtgtcaacag cgagcgcgat gactcaaaag
    41281 taacaccaga tgcaccattt ggacctggac ctcgcgacgc attgaaacat atgttagctt
    41341 atggcgaacg tgatggattt aaagtaaaaa atgtcgataa ctatgcaggg catattgatc
    41401 ttggcgaagg agacgaaacg ctagggatat ttggacacat ggatgtcgtt cctgcaggag
    41461 atggctggga cacagatcct tatgaaccag taatcaagga tggaaagatc tttgcacgcg
    41521 gatcaagcga tgacaaaggt ccaagtatgg cagcttacta tgcgatgaag atcattaaag
    41581 aacttgactt gaaactatca aaaaaagttc gcttcgtagt cggcagcgat gaagaaagcg
    41641 gctggggcga tatggcttat tatttcgaac atgaagaaga accagatttt ggtttctcac
    41701 cagatgctga attcccaatc atcaatggtg aaaaaggaaa tgtttcttta gctttacgct
    41761 tcaaaggcga caatgcagga gattatgtct tgaaatcttt tgtttccgga cttcgcgaaa
    41821 atatggtgcc aggaacagca actgcagcac ttcaagtacc aagtgcagat gcagctatcg
    41881 cgatggaaga agcattttac caattcatcg aagcaaatcc agtaagcgga acgattgaag
    41941 cggacaatac gtatgtaaaa atcgaattag ttggtaaagg cgcacatggt gcaagcccac
    42001 aatctggtat caatgcaggt tctttcttgg cattgttctt agataactat gaattcctag
    42061 gatctgctaa acaatttatc catgtagcag ctgcttatgt ccatgaagat ttttatggag
    42121 aaaaactagg agtcgcttat gaagatgaaa aaatgggcaa attgacaatg aatgctggac
    42181 tatttgcttt tgaagaaaat ggtacagagg aagcgaactt catcaatatg aatttccgtt
    42241 ttccaaaagg tgtaacagta gacggattgc aaagtgacat cgaacaaaca gtggggcaag
    42301 aaggcgcaac agttactcga ggtgctcgcg taatggaacc acattacgta ccaatggatg
    42361 atccattggt ggctacatta ttgcaagtct atgaagacca cactggagaa aaaggctacg
    42421 aacaaatcat cggtggcgga acttacggac gtttgttgaa acgtggcgtt gcttatggag
    42481 cgatgttccc aggatatact gatacaatgc atcaagcaaa cgaatttatg agtcttgatg
    42541 acttgttcag agcaacagca atctatgcag atgccatcta tcgtttggcg aaataattaa
    42601 ttaaaaagag gatcaagaat tgcaaattat ttttgcagtc ttgatccttt ttttactttc
    42661 tactgtggta ttcatgataa acatgatata gattcaattc atattctttc ttagcgttcg
    42721 tgacgactgt atccaaaatc aaccctgtta ctaatgaaag aagtgctaaa gtcatcaatc
    42781 cagtacttaa aatcgcagaa gggatgcgtg taataaagct tgtcagcata tattcgcgaa
    42841 tcacaggaat ccccgtgacc aatccaaata aaaagaagaa gatggtccaa atcccaaaga
    42901 aaagcaaagg cttataatct ttaaacattt taataatcat catgatcact ttgaatccgt
    42961 cagagaatgt attcaatttt gattcgctgc cttcaggacg atcacgataa tcgattggga
    43021 tttcaacgaa cttgaatttt ttatctaaag catggatcgt caattccgtt tcgatttgaa
    43081 aaccagaact cataatagga aaacttttga caaagatacg attgaatcct cgatagccgg
    43141 tcatgacatc aagaattttt gttttataca ttctagtaat tgtatttcta acaaggttat
    43201 ttccaaaatc gtggaaaggt ctcttattct catcaaagta ggttccattt gataggcgat
    43261 caccaatgac catatctgct tcaccagaac gtaatttctc gagcaaacca tgtacagctt
    43321 ctgcaggata agtatcatcg ccatctacca ttaaataata gtcggcatcg atatcaaaga
    43381 acatttggcg gatcacattt ccttttcctt gacgaggttc tttttttacg attgctccac
    43441 cttgaacggc caattcgtat gttcgatcgg tcgaattatt atcatagaca taaatatctg
    43501 cttctggtaa ttctcgttta aagtctgcaa tgactgttga aattgttgct tcctcattgt
    43561 aacaaggaat cagaacagca attttttctt gttgttccat ttttcactct ccttaactat
    43621 agaaaacaaa agctaaatta aaaatacctc ataatcaaag gaaatgctag tttttcccgc
    43681 taaatatcat ttatttaaaa agaaaatact ggaatatatg tttggaaagc tctatctaaa
    43741 aaaccaccca ctacaaaaga aggacatgat acctctcttt tgaatagtgg gtgcgtattc
    43801 gttctctcac ttttttgacg tattaatctg ttgcaccttt ttttcttgaa atttctaata
    43861 cggttcctgt atgagcatct gctaaaaatt cataataaac agtttcgcca tcttctattc
    43921 gagaaagacc tccccgataa gcactcgacc gaacggcgaa tttcctaata ggttcctttt
    43981 caaaagagat ccaagaacct tcgattgcac cttcttttag aaaagatgac ttgatatttt
    44041 caagtacttg gtctgctgac aatacttttt tgcgatgata ccaaatcgtt gaagctaccc
    44101 cgctcaataa tcctagaccg attccaactg ctaacccgcc tttaaaatag cttagttcgc
    44161 tttcttcata catgtggaca tacctccttc ttctcacttg ttactccttg tgcttatttt
    44221 accacactct catattttct ttgaaataaa taaccgctac cagaaaaaat aagctataat
    44281 aaatacgatc ggtctgcaga aaaaatcata ttttatccgc agatcaatat aagtctgaga
    44341 ggagtttagt ctgaaattta gacgaatagc atatggaaga aaaaacattt caacgaatca
    44401 aagagttaac agaattacaa ggaacaagcg gttttgaaca agatgttcgc gcttatatgg
    44461 aaagtcatat ggaaccgctg gtagatgagt tacagttaga tggtttgggc ggcatttttg
    44521 gtctgcgcca tcatgaagaa gcggatgcac cccgtgtaat ggtcgcagca catatggatg
    44581 aagtcggatt catgctgaca caaatccaag aaaacgggct ttttaaagtc gtacctctag
    44641 gcggctggaa tccttacgtt gtttctgctc agcgttttac acttaaaacc tctactggta
    44701 agaattatcc atgtatttct tcttccgttc ccccacattt attgcgagga acaagcggac
    44761 aaaaatcagt agaagtaacc gatattttgt tcgatgctgg gtttgaatca agagaagagg
    44821 caatgagtta cggtgtcctt ccaggagaca caatcgttcc ttacgctgaa acgatcaaaa
    44881 cagccaacgg aaagaatatt atcagtaaat catgggacaa ccgctatggc tgtacaatgg
    44941 tattagaagc tttagaagcg ttgcaaaatg aaacattagg tcatacattg attgcaggcg
    45001 cgaatgtcca ggaagaagta ggcttgcgtg gttctaaagc ttctgtcaat aaattcaagc
    45061 cagatctgtt ctttgcagta gactgctctg cagcagatga tacagtgacg aaaaatggca
    45121 cattcggaca tttaggagaa ggtacattga tgcgtatcca agatccaggt ttgatcatgc
    45181 ttcctcgttt gcgcgagtac ttgctggata tcgctgaaac aaacaatatc ccttatcaat
    45241 actttgtttc aaaaggcggt acagatgcag gtgctgctca tacacaaaac gaaggaatcc
    45301 caagtacagt gattggcgta gtgggacgtt atatccatac gcatcaaacg atgttcagta
    45361 ttcgcgattt tgaagctgca cgagaaatgt tgattcaaac actgaaaggt ttggataaat
    45421 caacagtgaa tacgatcgta tacggaaaat aatgcgatag tgaaactata aaatctggca
    45481 aaagattgct ttttgccaga ttttttttat aaaaagagga tcaatgtttg ttagttcgaa
    45541 agaaaggtgt ataatttaat tgaaaaatac ataaacagaa agtagaggac aaagaatgat
    45601 tatcccaaat agtttagaag aattagcagg ctacgtagaa actggaaaga gtgtattttt
    45661 ctttactgcc ggctggtgcg gagactgccg ttttatcaaa ccgcaaatgc ctgaaattga
    45721 aaatgacttt tctgattggc aatttattga agtagaccgt gacaagtaca tagatgtagc
    45781 cgctgaatgg aacatttttg gtatcccaag ttttgtcgtg atccaagacg gaaaagaatt
    45841 aggtcgtcta gtgaataaag atcgtaaaac aaaacaggaa atcgaatcgt tcctagaaag
    45901 tgtaacaaaa ggctgacatc tgttaggagg ggtcaagatg aatcaagaat ataagaatat
    45961 tttagtaggt atcgacggta gtgaacaagc acttgctgct ttcaaaaaag cggtagaagt
    46021 ggctcgccgt aataatggga aagtatatgt agcaaacgta atcgatcagc aattttataa
    46081 ctttatgggc tatgcaccta ttgatcaaaa tctagtcgat cagcaaactg aaacagccaa
    46141 ggaaatgatc gaagaatgta aagaatatgg gaaatctgtt gattacacaa atatagaagg
    46201 aattattgca tatggttctg ttcgtgaatc catggcagtc aaattgccaa aaaaatatga
    46261 gatcgatcta atcatggttg ggcagtcagg tctaaatgca gtcgaacgct ttatgacagg
    46321 aagtgtagcc agctacgtga tacgtcattc accttgtgat gtcttgatcg tttctgacga
    46381 agaagaacag ccaagtaatt aagcaagtgg aacttgtacg acctttttaa tcaattaact
    46441 aaaacagtaa agggactgtg acaaaagtct tgtcacagtc ccttgttacg aataaatggt
    46501 gttccagaag aggcttcttc ggaaataaag catgaaaaaa atttcatgca gtgaatgcaa
    46561 ttttttgtta agataaatct cagcaaagga taatggagga aagaacatga tttttgctta
    46621 taacaaagca cacgtcggag acaccttgat ggttattata gccgacgata aaggaacaga
    46681 aaacactgtt gaacgcaaat ggaatgttgc tcggatcaaa gatgaacaag gtcaagttgt
    46741 tgcttggaac tttttccata tctccgatca tctaacaatc gaagggaacg gccaagtaag
    46801 cttaacagat gaggaattag cgaaattgaa tcgattgatc aaagaagcag gattcgaaga
    46861 acagcttgaa gctgatcatg aaccgaagat cgttgtcggg tacgtaaaaa catgcgtccc
    46921 acatcctgat tctgaccatt tatcgattac tgagacagaa gtagacaatg gtacagtatt
    46981 gcaaatcgtt tgcggtgcac ccaatatcga agctggacaa aaagttgtcg ttgcaaaacc
    47041 aggagctatg atgccagatg gaatgatgat ctggccagga actttgcgag gggtagatag
    47101 ctatggaatg atctgttccg ctcgtgaatt gcatttgcca aatgctccag caaaaaaagg
    47161 aatcttagta ttgcctgagg atgccgtagt cggagaagca tttccaaaat aaagaggttg
    47221 tgacaagtct ttgtcacaac ctctttttta ttaattttca ctattttgat tttgttttaa
    47281 tgccgattga tcgatcgtca attcaacagt agttgttttt tctttcgagc cttcatagta
    47341 agtgattttg acagaatctc ccactttttt cttatacaaa gcagattgaa gttctacacc
    47401 agaagaaact tctttgtcat cgatcttagt aatgacgtcg tattgtttca atccagcttt
    47461 ttcagccggt gtagctgttt ggacatttgt cacgatgaca ccgttagtta cagatgaagg
    47521 aatcttcaag atttgttctt gttgctgagt agaaacggca gataagtcga ccattgtgat
    47581 acctagagct ggacgtgtca cttttccgtc tttttccagt tgattgatga tattcactac
    47641 atcgttactt ggaatagcaa atcccattcc ttctacgctt acattagaag tagattcaga
    47701 agtacttgcg atcttacttg agttgatacc gataacttgt ccttcgatat taactaaagg
    47761 accaccagaa tttccagggt tgattgctgc atctgtttgg atcgcattga tattgactgt
    47821 ttcgttcgat tcattcgtac ttgtcacttg tcggttcaag gaagaaatga ttcctgaagt
    47881 gacagaattt gcatattcag atcctagtgg ggaaccaatc gcaatcgcag gctcaccaac
    47941 cttcagagca cttgagtcac caaaagaggc aactgtttcg actttgtctg aattgatctt
    48001 caacaccgct aaatctgaat aagcatctgt tccaactaat tcagctttta ccttcgtacc
    48061 gtctttcatc aagacttcaa gaccttgctg gccatctact acgtgattat tcgtgactac
    48121 ataagcagta ttcccgtctt ttttgtagat cacgccgctt ccttcactat aagcttccaa
    48181 attactatca tctgagctgc tactttcttc ttgctgcccg aatagtccgc caaaaccgct
    48241 tgattggttt tgactttgta agttgataac agaaacgaca gcgtcttgaa ctttatctac
    48301 cgctttggtg atatcagaat ctacattgac tttgacattt tccacaactg tttcaccggc
    48361 agaattctga ttgccgcttg tagcagtaga actattgttg ccagtgccca tcgctgcata
    48421 aaaaatgcca gctgtcagta gtcctccaac gatccctcca acaagcccca gacctaactt
    48481 acgccagagg ctattatttt tacttttttt catctttggt gtcacatttt ttctatccat
    48541 gtgttcctcc tccaattaca ttcatttatc tactgttagt atagtcttat ttgttgactt
    48601 tagtctactt tgagactgtg aactttttat gaaaaacttt aggaaaaatc attgttttca
    48661 gatgaaaata tttgattttc tttttccaca gatactgtgt aaaactacgc ggataggatt
    48721 ggaaaaataa gggataaaac atatccacag cctgtgtata aagtggataa attcttataa
    48781 aacgtatgtt tgcctaatga atgtgatgaa ataaggtaaa ataacactgt tttctgtgga
    48841 taaacctgtg gatgttgtgc ataactgttg gggaaatctt tttaacaaaa atagccaaaa
    48901 taaacatata gacgaaaaaa ttgattataa taaacaaagt gagcatgaag accaaaggag
    48961 agaaaacatg aatatcaaaa ttatctcagt aggaaaatta aaagaaaaat acctgatcca
    49021 aggtatcaat gagtatgtca aacggctgaa tgcctatgca aaaatcgaat tgatcgaagt
    49081 tcctgacgaa aaagccccgg agaatttaag cgaagcgcaa atgagacaag taaaagaaaa
    49141 agaaggggaa cggatcttag cgaaaatcaa agaacaagaa tacgtctatg ccttagcaat
    49201 tgaagggaaa aatcctacaa gtgaatcttt tgctaaacaa atcgaccaat taggtatcca
    49261 aggaaaaagc caccttgttt ttgttatcgg cggctcttta ggactcagcg aagccgtcat
    49321 gaaaagaagc aatgctcaga tctcttttgg aaaaatgacg tatccacatc aattgatgcg
    49381 tctgatcctt gtcgagcaaa tctaccgtgc cttccggatc aatgcggggg cgccttatca
    49441 taagtgatgc ggtttttatc attgatccta aaaatcttag caagacaaaa agtacgtaag
    49501 aaagtaaaga ctaaatactt cggaggaaca aatgaataac aatgataggt tattgcgatt
    49561 gcgttatgcg attgatttga aagatacgga tttgattaaa gcttttgagc taggcggtgt
    49621 accactgact aaagaagaag ctcaggcggt actgaccaaa gtacaggata agaacaaaga
    49681 taatgcagaa aataatgtgt atgaaaaaac catcaacaac caagtttttg acgcattcct
    49741 aaatggcctg attctcttgg cgcgtggtcc gcaaaaagat aagccgatag tagacacgcc
    49801 gcaaaaaagc aaggaaatca aatatatcaa caatgtgttg ctaaaaaaat taaaaatcgc
    49861 cttgtctatg accactgatg atattttaga cgtttttgct gaggcagaaa tctatccatc
    49921 aaaaggcgaa atcggggcat ttttgagaaa agaaggccaa cgaaatttta agccttgcgg
    49981 agataaatat atgcgtaatt ttctcaaggg gttaggaatt tataatcgga gaaaagtata
    50041 aagaaatttc atgagaaatc aaaacaatgg ttgttttgat gagagctagt ttttgtatga
    50101 gattaaaata ttatcttaat cgaggagctg gattggtttt atgaatgatg aatataagaa
    50161 tgatgaagat aagatgcttt ttgaagagat agagaatcga tgtaggctca attttgagct
    50221 tcggggaaag atgtctttaa tacaacaaaa aaagtattta gcgaataaat cagagtttac
    50281 tctgggacat gttgaaaaat taatctcgga ttggattagt agtagaagcg aatttacaaa
    50341 aataaaacag ccgattaaat ttgacatgaa aaaacttttg ttaaataaga gtgagatagg
    50401 taatagagat caatatatta gagctaaagg gcaagaaata attgattcat taggtgaaat
    50461 gaggtcatac aattatttgt atgtaacaca tagagctgat ggaatggtca ttactgtggg
    50521 gaaatcttct tctaatgata tttttttaga tggagatctt ttttatcaac tcaatacaaa
    50581 tcacttgtct ggcactgaaa atataatttt aaggacggaa tatggcaatg aaatatttgc
    50641 aaaatatgat gagattttaa aaaattattt ggactgggct tggataattc cggttgagtc
    50701 aggagatgct aagaaactgg agagattatt gggcgatgaa ctaattaata aaaaagtacc
    50761 aattttaaat tattattccc atagacaata aaaggctatt tttcatgata atactagtta
    50821 taactgtaaa aatggaagaa aatctgggaa agaagttttt aaataagtgt attgttcgat
    50881 tttaataaat aataagcaat accatccgtc tgtgttgcgc aacatcgtac tacaatgaat
    50941 attttttcac aaaaagaaaa tcatccatcg aatgaatgga aggttttagt atacacgagg
    51001 ttaatgcccc ctcttttata atcagaggag tgaggttttt tctatgaatg tttctatttt
    51061 cttattgcta gtctagtttc tcttacgatg aaattgggat tctattccag tttttattga
    51121 tttgctgata aaataacttg aatggtggat ataaacatga taaataagag aagaataaca
    51181 aaacaaggtt gtgaaatgat tctcaaatga atataataga aagaaaaagg aggaagaatc
    51241 aatgaaaata gcaattgcag gcgctggcgc aatgggaagt cgctttgggt taatgcttca
    51301 ccaaagtggg aacgaagtat tattaatcga tggctgggca gaacatgtcc aacaaatcaa
    51361 agagcatgga ttacaagcaa attttaatgg taaagaggta gaagcaaaac taccaatcgt
    51421 tcttcaatcc gaagtagaaa aagaagatca agttgatctg attattctat ttaccaaagc
    51481 gatgcagctg gaaaaaatgc tgcaggatat ccaatcatta atcaaaaaag atacagaggt
    51541 cttatgtcta ttaaatggta tcgggcatga agatattatt gagaaatttg taccaatgga
    51601 aaatatctat attggaaata ccatgtggac ggcaggtctt gaaggtcctg gtcaggtcaa
    51661 attatttgga agtggttcag tagaattaca aaatttaggt gatggaaaag aagcagctgc
    51721 aaaaaaatta gcagacaaat tgtctgaatc aggattaaat gctcattttt ctgacaatat
    51781 tcactattct atttatcgca aagcatgtgt gaacggaaca atgaacggac tatgcacaat
    51841 cttagacgtt aatatggctg agctaggaaa aacatcgact gctcataaaa tggtggcgac
    51901 gattgtcaat gagtttgcca aagtagcagc agtagagaag attgaactag atgtcccaga
    51961 agtcattgca cattgtgaat cttgttttga cccggaaaca attgggttac attatccttc
    52021 aatgtatcaa gacttgatta agaaccatcg attaacagaa atcgattata tcaatggcgc
    52081 aatttctaga aaagggaaga aatatggtgt tgcgacgcct tattgtgatt tcttgactga
    52141 gcttgtccat gcaaaagaag atagtttgaa cgtaaaataa aggagagatt gaatggaaac
    52201 ttcacaaaaa atatcaccga aaatttttct gaataaagtc ctcgctggta cagcaacagg
    52261 aatcattatt ggattgattc ctaatgcagt attaggtgcc attttaaaat attttagtgc
    52321 gtatcccttt gcggtaacga tcgcacagtt agcagttatt tttcaactag caacaccttt
    52381 gatcattggt ggtttgattg ccttacaatt tggatttgat ccgatgagaa tgatggttgt
    52441 agccggagct tcttttgttg gttctggtgt agtcaaattc acacctgatt tgggtgaaac
    52501 gggtgtttac gttggtgctg gtacaggcga tattattaat acgatgctga cagcatcgat
    52561 tgctgtcggg ctgattttac tgattggaaa tagttttggg tcagtgtcga ttgtgttaac
    52621 accgattgtt gtaggtgtag gtgcaggttt acttggtttt tatttattcc cttttgtaac
    52681 agcaattact tctgcaattg gatcattgat taataacttc actaccttac aaccgctgtt
    52741 aatgtctatc ttgattggtt gttcctttgc ctttttgatt atctctccta tttcaacagt
    52801 agcaatcgga atggcaatcc aactagatgg tgtttctgct ggtgcggctg cgatgggcgt
    52861 agctgcaacc acttttgttt tagtagtgaa ctcttggaag gttaataagt caggtgtgac
    52921 aattgcgatt gctttaggcg ctatgaagat gatgatgcct aatctattta gaaaacctgt
    52981 gattcttatt ccttgtttag ttagtgcagt gattacagct attcctgtcg ctctattttc
    53041 tatttcaggt acgcctgctt ctgctggttt cggcgtggtc ggacttgttg gtccgttggc
    53101 ttctttagat gcagggctaa atggctttct tgttgttctt tgttggttag tcatccctgt
    53161 ttttgcggca ctaattactc aatttttatg cgagaaagta tttaaactgt atgatcgaga
    53221 agaagtcttc aaatttttag gctagtagat tttactaaga aattttcaat caatggatgc
    53281 gtaagtgaga tgtcaacaac atctgactta cgtttttttg cctttttgag taggagattg
    53341 atgctgacaa ctgaactctt cagtgccatt cgatttttta aaatgtagaa gaaactcacc
    53401 tttatgttat tgattgttca aaaggcaact agaataaaaa tatgtgttaa aatgagaaaa
    53461 aatttgattg ttggatgtat cgaataatca ctaaaaagta ggagaagaaa atgatttttt
    53521 tgcaaaaata tggtttttat tttttattat taggtgtgat tagtgattta tcgacaccgt
    53581 atatccttgg ccttttttat cccaaactga atcaaatgac taccgtaatt agtgtgtttg
    53641 gtgacgtaga tagtccagtc agacgtgctt tcttggtctg gtcagttgta tctggacttt
    53701 tttttgttct ttcgttgcct gcgttgtatc acctatttat tggaacatca aaaacacttg
    53761 caatacttgc tgttgcaaca gttggtttat atgggatagg tgattgtatt tttactgggt
    53821 tattcagtat caatacgaat gaaagctctt ggaatctatc gacttggatc cataatatag
    53881 gttctgggct aggctatgca ggctttctac ttttcccatt gttacttgtt ctgctttatc
    53941 gtcaaagtgg tcaaggtacg cttagccatt tttatcttgt tttaacagtt attagtttac
    54001 taattgcagg tctttacgga ttagcacgga ttccgtcgat tagtcagttt gccttcttta
    54061 agcaattggg cttctttcaa cgcttaagtt ttttctttaa ctatttgccg atgatttgtt
    54121 taagtttttt tcaactacga aagtagaaaa agcagtgtga agctgattaa gtaaaagaat
    54181 ttctctatgg gtaaccattc gtgtggatgt gttcgactaa gaatagagat gaggagagcg
    54241 aaaagcaagt tagtcttaac ttgttatgcg ttgtgctaaa tttcaggtag tcattttttg
    54301 aatgaataag aagaaaactt gaaagagggt gacttcatgt tagatgtgga gcagatggaa
    54361 atagaccttt ataatattat tttaaatcga aatacaagag aatgggaaag aacacaattt
    54421 gaagaggcaa aagaagacct agcaaaaatg tcgataaagc aggtgataga aaaactagag
    54481 gtcaacttgc gtccgctagc actacgagat aatttgacac cagatgcgat ggatttttat
    54541 ttaagaatca caggggagtc agcgagtgca aaggcttatg attatgccaa acataagata
    54601 acttcaccct tataccaaga acgggcgatt tttgccggtg gctgtttctg gtgtatggtt
    54661 gagccttttg aaacaaaacc aggtgtaatc tcagtgttat ctggttatac aggtggagag
    54721 accaaaaaac caaattacga tcaagtcagt ggtggatata ctgggcatgt tgaagctgtt
    54781 gagatcatat ttgatacacg tcaaataacc tatgaagagc tgttggagat ttattggcaa
    54841 atttcagacc ctacagatgc ctttggtcaa tttcaagatc gggggaaaca atatcgttca
    54901 attctatttg ttgttaatga aaagcaaagg caattggctg aaaaatcaag agaacaactg
    54961 attcaatcta accgatttag ccgtcctatc gttacagaga ttcgccaagc aaagactttt
    55021 tggccagctg aaaatcatca tcaacaattt tatcagaagc aacctaaaag atataaaaag
    55081 atcaagcatt cgcatcagct tcatttattt tttcagcgac atagatagag gaaggttgtg
    55141 gcgcaaagcg ttcagctccg acaaaataat gagcaactga caaaaatagc ttttcatatt
    55201 tttggacagt tatgaattat ttcgaggagt tgctttgaga acaccgagga aaaggttgtg
    55261 gcgcaaagca ttcagcttca agtcgcaagg aaacaggagg tatgacaagt cttttgtcac
    55321 aactcctgtt tttttactag cctttatttc catgtgaaag agaattcgaa ttgtagaatc
    55381 ttgatttttc tatggaattt tgtagagaat catcttgata attaatagac acctaatcga
    55441 attccacatt aatgatgaac taaattccgt ataaaagcgc aaacaataac tataa
//
LOCUS       DAFENC010000016        55222 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.016, whole genome shotgun sequence.
ACCESSION   DAFENC010000016
VERSION     DAFENC010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 55222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55222
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.016"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(151..2304)
                     /locus_tag="LP493_001238"
     CDS             complement(151..2304)
                     /locus_tag="LP493_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HBL2133399.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(2598..3446)
                     /locus_tag="LP493_001239"
     CDS             complement(2598..3446)
                     /locus_tag="LP493_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL2133400.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(3670..5610)
                     /gene="thrS"
                     /locus_tag="LP493_001240"
     CDS             complement(3670..5610)
                     /gene="thrS"
                     /locus_tag="LP493_001240"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HBL2133401.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDSDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(5947..6126)
                     /locus_tag="LP493_001241"
     CDS             complement(5947..6126)
                     /locus_tag="LP493_001241"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HBL2133402.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(6173..7996)
                     /gene="cadA"
                     /locus_tag="LP493_001242"
     CDS             complement(6173..7996)
                     /gene="cadA"
                     /locus_tag="LP493_001242"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBL2133403.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            8274..10553
                     /locus_tag="LP493_001243"
     CDS             8274..10553
                     /locus_tag="LP493_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL2133404.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(10646..11293)
                     /locus_tag="LP493_001244"
     CDS             complement(10646..11293)
                     /locus_tag="LP493_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133405.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(11472..12191)
                     /locus_tag="LP493_001245"
     CDS             complement(11472..12191)
                     /locus_tag="LP493_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2133406.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(12322..13473)
                     /locus_tag="LP493_001246"
     CDS             complement(12322..13473)
                     /locus_tag="LP493_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HBL2133407.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(13690..14430)
                     /locus_tag="LP493_001247"
     CDS             complement(13690..14430)
                     /locus_tag="LP493_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL2133408.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(14434..14757)
                     /gene="rsfS"
                     /locus_tag="LP493_001248"
     CDS             complement(14434..14757)
                     /gene="rsfS"
                     /locus_tag="LP493_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HBL2133409.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(14814..15407)
                     /gene="yqeK"
                     /locus_tag="LP493_001249"
     CDS             complement(14814..15407)
                     /gene="yqeK"
                     /locus_tag="LP493_001249"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HBL2133410.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(15391..16041)
                     /locus_tag="LP493_001250"
     CDS             complement(15391..16041)
                     /locus_tag="LP493_001250"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HBL2133411.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(16051..16362)
                     /gene="yhbY"
                     /locus_tag="LP493_001251"
     CDS             complement(16051..16362)
                     /gene="yhbY"
                     /locus_tag="LP493_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HBL2133412.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(16378..17487)
                     /gene="yqeH"
                     /locus_tag="LP493_001252"
     CDS             complement(16378..17487)
                     /gene="yqeH"
                     /locus_tag="LP493_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HBL2133413.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(17484..18011)
                     /locus_tag="LP493_001253"
     CDS             complement(17484..18011)
                     /locus_tag="LP493_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HBL2133414.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(18191..18976)
                     /locus_tag="LP493_001254"
     CDS             complement(18191..18976)
                     /locus_tag="LP493_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HBL2133415.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFHQY"
     gene            complement(18969..19838)
                     /locus_tag="LP493_001255"
     CDS             complement(18969..19838)
                     /locus_tag="LP493_001255"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HBL2133416.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(19839..21218)
                     /locus_tag="LP493_001256"
     CDS             complement(19839..21218)
                     /locus_tag="LP493_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HBL2133417.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(21226..21645)
                     /gene="fabZ"
                     /locus_tag="LP493_001257"
     CDS             complement(21226..21645)
                     /gene="fabZ"
                     /locus_tag="LP493_001257"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBL2133418.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(21670..22146)
                     /gene="accB"
                     /locus_tag="LP493_001258"
     CDS             complement(21670..22146)
                     /gene="accB"
                     /locus_tag="LP493_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HBL2133419.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(22149..23384)
                     /gene="fabF"
                     /locus_tag="LP493_001259"
     CDS             complement(22149..23384)
                     /gene="fabF"
                     /locus_tag="LP493_001259"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HBL2133420.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(23403..24140)
                     /gene="fabG"
                     /locus_tag="LP493_001260"
     CDS             complement(23403..24140)
                     /gene="fabG"
                     /locus_tag="LP493_001260"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HBL2133421.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(24152..25069)
                     /gene="fabD"
                     /locus_tag="LP493_001261"
     CDS             complement(24152..25069)
                     /gene="fabD"
                     /locus_tag="LP493_001261"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBL2133422.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(25176..25400)
                     /locus_tag="LP493_001262"
     CDS             complement(25176..25400)
                     /locus_tag="LP493_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBL2133423.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(25453..26415)
                     /locus_tag="LP493_001263"
     CDS             complement(25453..26415)
                     /locus_tag="LP493_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HBL2133424.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(26425..26865)
                     /locus_tag="LP493_001264"
     CDS             complement(26425..26865)
                     /locus_tag="LP493_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL2133425.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            27171..28136
                     /locus_tag="LP493_001265"
     CDS             27171..28136
                     /locus_tag="LP493_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBL2133426.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(28193..28423)
                     /locus_tag="LP493_001266"
     CDS             complement(28193..28423)
                     /locus_tag="LP493_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HBL2133427.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(28509..29395)
                     /locus_tag="LP493_001267"
                     /pseudo
     CDS             complement(28509..29395)
                     /locus_tag="LP493_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
     gene            complement(29484..30707)
                     /locus_tag="LP493_001268"
     CDS             complement(29484..30707)
                     /locus_tag="LP493_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBL2133428.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(30724..31770)
                     /locus_tag="LP493_001269"
     CDS             complement(30724..31770)
                     /locus_tag="LP493_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBL2133429.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIRSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(31934..33661)
                     /gene="ptsP"
                     /locus_tag="LP493_001270"
     CDS             complement(31934..33661)
                     /gene="ptsP"
                     /locus_tag="LP493_001270"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBL2133430.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(33661..33927)
                     /locus_tag="LP493_001271"
     CDS             complement(33661..33927)
                     /locus_tag="LP493_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HBL2133431.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            34406..36640
                     /locus_tag="LP493_001272"
     CDS             34406..36640
                     /locus_tag="LP493_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL2133432.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            36788..37108
                     /locus_tag="LP493_001273"
     CDS             36788..37108
                     /locus_tag="LP493_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBL2133433.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(37313..37537)
                     /locus_tag="LP493_001274"
     CDS             complement(37313..37537)
                     /locus_tag="LP493_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HBL2133434.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(37735..39315)
                     /locus_tag="LP493_001275"
     CDS             complement(37735..39315)
                     /locus_tag="LP493_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HBL2133435.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(39716..41092)
                     /locus_tag="LP493_001276"
     CDS             complement(39716..41092)
                     /locus_tag="LP493_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBL2133436.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(41220..42338)
                     /locus_tag="LP493_001277"
     CDS             complement(41220..42338)
                     /locus_tag="LP493_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL2133437.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            42480..42914
                     /locus_tag="LP493_001278"
     CDS             42480..42914
                     /locus_tag="LP493_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2133438.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(42992..43525)
                     /locus_tag="LP493_001279"
     CDS             complement(42992..43525)
                     /locus_tag="LP493_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HBL2133439.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(43619..44797)
                     /gene="mutY"
                     /locus_tag="LP493_001280"
     CDS             complement(43619..44797)
                     /gene="mutY"
                     /locus_tag="LP493_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HBL2133440.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(44790..45587)
                     /gene="recX"
                     /locus_tag="LP493_001281"
     CDS             complement(44790..45587)
                     /gene="recX"
                     /locus_tag="LP493_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HBL2133441.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            45694..47076
                     /gene="rlmD"
                     /locus_tag="LP493_001282"
     CDS             45694..47076
                     /gene="rlmD"
                     /locus_tag="LP493_001282"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBL2133442.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(47250..47828)
                     /locus_tag="LP493_001283"
     CDS             complement(47250..47828)
                     /locus_tag="LP493_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HBL2133443.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            48150..48620
                     /locus_tag="LP493_001284"
     CDS             48150..48620
                     /locus_tag="LP493_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HBL2133444.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(48728..49954)
                     /locus_tag="LP493_001285"
     CDS             complement(48728..49954)
                     /locus_tag="LP493_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBL2133445.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(50708..50908)
                     /locus_tag="LP493_001286"
     CDS             complement(50708..50908)
                     /locus_tag="LP493_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL2133446.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(51042..51650)
                     /locus_tag="LP493_001287"
     CDS             complement(51042..51650)
                     /locus_tag="LP493_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBL2133447.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(51735..52205)
                     /locus_tag="LP493_001288"
     CDS             complement(51735..52205)
                     /locus_tag="LP493_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HBL2133448.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(52253..53167)
                     /locus_tag="LP493_001289"
     CDS             complement(52253..53167)
                     /locus_tag="LP493_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBL2133449.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            53313..54116
                     /locus_tag="LP493_001290"
     CDS             53313..54116
                     /locus_tag="LP493_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HBL2133450.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            54294..>55222
                     /locus_tag="LP493_001291"
     CDS             54294..>55222
                     /locus_tag="LP493_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBL2133451.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQV"
BASE COUNT        15874 a        11663 c         9437 g        18248 t
ORIGIN      
        1 aatttttgtc acaacctttt ttgccgagta aacggtgttc aaaagccagt ttctcggtat
       61 gaagtcaaat ttaagcaaaa atgtgagaag ctattttcac aaaatttttc ttcatactcg
      121 aaactaagcg gctttttcac gacctctttt ttattttgcc atgaacatat cataatacgc
      181 gtccattatt tctttagcaa tcgtcaagtt tatgtggtct tgttcgtcta ataagttcgg
      241 caagacaaca ctgatggcaa tttccggatt gtctgttggt ccgtatgcca cgatattact
      301 attgactgtc gcaatatctg gatgaccttc cgcaaccgtt tctgcagtcc ctgtttttgc
      361 ggaaaggtcc attttcgcac tggctaatgg tttggctgtt gtgtaaggat cggtaccatg
      421 gacaacttgg tggaatcctt cacggaggat cgccatattt tctgcagaaa tattgaccgt
      481 attttctact gttgtgccaa tttctttctt cacttcaccc aagtttccat tttcgtcatt
      541 gccatagatc gctttgacta ggtgcggctg tactcgtttc ccgccattag cgactgttga
      601 agcatattga gctaattgga ttggtgtata tgtgtcaaac tgtccaaatg ccaaatcggt
      661 aaagttacct ggagcatacc attctttgcc attatccgca ttgaacttct tcatataatc
      721 aacagaacgt gagatcccag gagattcatt cggcaaatcg atcccagtcg ttgtaccaag
      781 accaaactct ttgaaagagt ctctcaattg ctgataagct ttagcttctt catctaaact
      841 aggtagtccc attccaggtg tatagtctag tcctaacatc tttaacgcca ctttgatcat
      901 atacgtatta gaagacaatt ccgatgcttt gactgcatca agagcaactt gtccgcttcg
      961 attaaagaca gagctttttt ctgaagcacc ttgcagacga atcggctcat caatcaaaac
     1021 ttgatttccg ctgatcgcgt tacttgccca gcctgctgtc aaagtaccag ccttgactac
     1081 agaccctgga tcaaaggcgc tagtaatcgt gcctaaagca ttctcggtga tttctttgga
     1141 accttgttca tgactgaaac cagtcattgc tagcacttct cctgtctgag gattcatagc
     1201 cactgcataa gcaccaggcg aatactgtgc tttgccgttg ttgatcaatg tttgataatt
     1261 ccttttcaaa atttcttcta cttttgattg gaattctgca ttcatagata acattaaatt
     1321 agaacctttt tccccagaga agatttcttt ttgattcgaa acatttcctt cattatcaag
     1381 ggaaacttca tattgggttt tggttccttg caggacatct tcatattgtt tttccaaata
     1441 actttgtcct acacggtcat tccgagaata accttttgct aggtatttct ctgcttcatc
     1501 tgctggaagt ccttgctttt cagtcgtcac actgccaaga atacttttca gtgaacttgc
     1561 tgcattatat tctcgtgtcc agtctgtgcc agtcgaaact cctggaagtt cagaagcgcg
     1621 ttctgccaca acagctaact cttgatcagt aacaccagag tttttgatat agacagtgtt
     1681 taattcatat gcactattca tccgtttaaa gatggtagca atttttaatt gctcctcgtt
     1741 taaattaatc tcatcagctg tgactttatt gaccatcgca ctatattgtt cgctgttccc
     1801 taattgcttt tcttttgccg aaagtctttt tgtggcttct ttcaaatgtt tgggatcagc
     1861 cagccaaaaa tcttttttat ctctatctgt cagattttca tctaccggaa catcgatcag
     1921 cgagttcagc ttcgttgcga tttcaagcaa atctttagcc gtaacttgtg ttcctctcgt
     1981 atatgtgatg gcctgattcg ctttattcgt aactaaagct tttcctgtgg agtcgtagat
     2041 cattccgcga ggagtacttt cttggaccgt aatcgtagaa gtagacttca ctcgcgcctc
     2101 catctcttcg ccgttcacga tctgcaaata acccaatcta gcaatcaacg caacaaataa
     2161 cgtaaatata atgaaaaaaa gaaaatttaa gcgaaaagga acatgggacc ggcgaaacgt
     2221 tttgttctta ggttcttgtg caccttttct tattttttct aaccaagaag tatttaatat
     2281 ttttttcata aaatctttca tcatttccta tccttccgcc tatttacatt catgcttcat
     2341 tgtacccaaa aacttcttaa taaaaaagaa aaaatgggcg gagcaagaaa ttctttacct
     2401 aatttcaaga taaaatcaac tttttgtttc acagcaatca cttaaagtta catatccaac
     2461 tatttttttc attaaaaaat aaacttattt ttgaaaatta tgttttctta agtcgtgaaa
     2521 cactttgatg gatcatttat ttgtggaaaa ctacgttttg ttattctaaa aaacttatat
     2581 aaaaaatagt aaggttttta tttcgaatcc ataaaatatt cttggattgc ttctcgtgtt
     2641 tttttcactt tttcgctaag cttttcgttt ttagccatat agaaataaaa aatgatatcg
     2701 atcgtagcaa attgggccaa aagtgaatta gttgccgcac ttcgattcgt gatttctttt
     2761 ggtctagatg tttgtacgag tacatcggct atcttgctaa gcgggttatt tccaaattgc
     2821 gtcaacgcaa tgatttcgat attcatgctt ttcgccagct cggctaatgc gactacatct
     2881 gcacttctac ctgagtttga aacaagccaa agcactttct ttttctcatt gctgacaagt
     2941 tgcgggagca agacgtggat atctttttca aaaatgattg gcttaccgac acgagaccat
     3001 ttttgcagaa tatcttctac tactaaagaa gaggcgccaa ccccatataa aaaaacagtc
     3061 tctgccgatt ccaaacactc tacgactttt tggatcgttt cttcttctag aatatctact
     3121 gtttctttta tcgctacttg tgcattgtta ccaagtttgt ttttgataga gtaaaaggac
     3181 tcatttgctt ctatatcact aaaaccttca tcgattccag tctgtagttc tgttgaaatc
     3241 gtgattttga agtccgtcag actttgaaaa ccgatttttt tggaaaaacg tacaactgtc
     3301 ggcgcactca acccggaagc ttctgctaat tcattagctg tcattgtagg gaccttctca
     3361 atattaccga taatgtagtt ggccaacttt ttttctgctg aagaataatc ttccatcata
     3421 ctttcaatac gactaattac gctcataagt tcctccaccc ttttaatgat agtctatgta
     3481 agtataccat atcagaccct tattcacggt cgtatactgg ataaaaaaca aaaaaacaat
     3541 ccgcccaaca gaatatctta tcccatcaat cccacagatt ctattgagca tctgtgtctt
     3601 tgaggaatac ctgttatcta ttgttcggat tgctttctat ctactacttt tttacaggaa
     3661 atttacctat tagttttctc tgctgtaatt tttgacttct gcttccatag catcaataaa
     3721 gatattcaaa tcttctacag ctgtttcttt acttccataa cgacgtacgt tcactgttgc
     3781 atcttccaat tccttgtctc caacaactaa ttggtaaggg atcttttgtg tttgagaggc
     3841 acgtatctta tagcccattt tttcattacg atcatcaact tctacacgca accccttcat
     3901 ttgcaaacgt tctttgattt cataagcata atcgccatgt gcatcaacag aaacagggat
     3961 gattgttgct tgtataggtg ccaaccatgt tggaaaagcg cctttgtata cttctgttaa
     4021 ataagcgaca aaacgttcca ttgtagaaac aattccgcgg tggataacta ctggacgatg
     4081 cgtattttcc ccgtcttctc caacatatgt caaatcaaag cgctctggca ataagaagtc
     4141 taattgtata gttgataatg tttcttctgt accaagagct gttttgactt gaacatctag
     4201 ttttggtccg taaaaggctg cctcgccttc tgcttcaaag taatctagtt ctaattcatc
     4261 catagcggct ttcagcattg cttgggcttt ttcccacatt gcgtcatcat caaaatattt
     4321 atctgtattg tttggatcgc gatagctcaa gcggaaacga taatctgtaa tattgaagtc
     4381 agcatatact gccaccatca attcaagcgt acgtttaaat tcatctttga tttgatcagg
     4441 acgaacaaat gtatgaccat cattcaacgt catttctcgt acacgttgta aacctgacaa
     4501 agcacctgat ttttcatagc gatgcatcat tcctaattca gcgatacgaa ttggtaattc
     4561 acgataagaa tggatcgtgt ttttgtagac catcatgtga tgagggcagt tcattgggcg
     4621 aagaacaagc atttcgccat ctcccatatc cattggcggg aacatgtctt cttgataatg
     4681 atcccagtgt ccagatgttt tgtacaactc aacatctccc attattggtg tatatacatg
     4741 ttggtaacct agactaactt ctttgtctac gatataacgt tcgatcgtgc gtcggattgt
     4801 tgcccctttt ggaagccaga atggcaaacc agaacctact tctggggaaa ccatgaacaa
     4861 gtcaagttct tttcctagtt tacgatggtc tctttctttt gcttcttcac ggagacggat
     4921 atattctttc aaagctttct tgtcaaaaaa ggctgtcccg tatacacgtt gcatcatttg
     4981 attgtttgag tttccacgcc aataagcacc tgccactgat aataatttaa atacttgtat
     5041 acggccagtg gatggaacat gtggtccacg acacaaatcg atgaattcgc cttgttgata
     5101 agcagtaatc acttcttctt ctggcaattc actaatcagt tctactttgt acggatcact
     5161 tgcaaaaatt tctaatgctt cctgttttga aagaacacgg cgttcgatcg gcagattttc
     5221 tttgacgatt ttcatcattt ctgcttcgat tgccggcaaa tcttctgcag ttacttggtt
     5281 ttgtccatta tctgaatcgt agtaaaaccc tgaatcgata gctggtccaa cgccaaagtg
     5341 gatatttgga tagaggcgac gcatggcttg ggccatcaaa tgagctgctg aatgacggac
     5401 taagccaagt gcatcttcat ggtctggtgt gatgatctca atacttgcat cttcctcgat
     5461 tggacgagtc aaatcaacga gttttccgtt cactttacca gctaaagctt tttttgctaa
     5521 gctttttgaa atgctttcag caattgccaa tgttgttgtt ccagactcaa attctttgac
     5581 tgcaccatct ggaaaagtaa tttttatcat aatagtttcc tccttgaaat gttttgattg
     5641 atcagatcat caagctgaaa aacaaaaaaa tcctagcatc tcttgaaaag agatactagg
     5701 acgaaaagtt cgtggttcca cctaatgttc aaacgcaaat gcgttcctca agcgttgtaa
     5761 cggtccgacc gcccttgctt caacaagggt ttcgaaagtg gtcatccttt ggttttctcc
     5821 tggaaaagtt tcagcctagc ttttcctctc ttatcgaaga ctctcaaatt cagttggctt
     5881 tctcatcaat caattatgtg tttatttaac cactaataaa tagaaaaatc aagtgggaaa
     5941 ctaaacttat tttttccatt ccccatttac accgtatgtt ccttttttca tctcattgat
     6001 gatgacatgg atgtgttctt ttggtgcctg cgtgttttta tgaacagctt ccgtgatatc
     6061 tttcatcata ttttctaatt gttccggact gcgaccttct actaattcga catgtacgaa
     6121 tggcataatg ctctctcctc tttctgatcg ttcttttttc aactcgattc tatcatacta
     6181 tgtttgtctt gggtactgaa tcaggaaaaa tggctggatc tttttttgct ctcaaggcac
     6241 tcaaaataga gaccgtatcc acgacttctt gcaaaacagc tccgaataat gcggggatta
     6301 gtcccgtact tgcaattaac atcaaaaaaa tacaaataaa gatgccaatc agtacagact
     6361 gtttcgctat tctcatcgta tctcttgaaa tcactactgc ttttgctaca cgcaagagat
     6421 catctttcaa gatgaccgca tctgcacttt cactagcagc tgtagaacca tgagccccca
     6481 ttgcaatacc gatatctgca gcagcaagtg ctggtgcgtc attcacgccg tctcctacca
     6541 tcgcaacagg tctttgatct ttagggatac tttctaaaat ggtcagttta tcttgaggca
     6601 agctacgggc atgtacagaa tctaattgga ctttttctgc aatcgtttga gcaatggcag
     6661 atccatcccc ggtgatcatc atcaaatttt tcacatcaag ttttcttagc tccttgattg
     6721 tctttgctgc ttctgggcga atctgatccg aaaataggat cgttcctgca aaagatcgat
     6781 caattgttac atagattgct gtattggacg tttctatttc ttcagctgaa acaaaagagg
     6841 cacgtccaat ctttacttca tgattattga ctactgcttg gattccttga ccggtcactt
     6901 ctttcagttg actaacagga tacagttggc tgtttttcac gttgttcact aacgaacgag
     6961 ctaagatatg gctagattcc tgttctgcac tagctgcata cagaagtagc tcttcttttt
     7021 ttattccatt gactggctga atcgcctcta cttccaatat ccctttggta agcgttcctg
     7081 ttttatcaaa agcaatcgtt tttgtacgtg cgagcttttc aatcgttgtt ccagttttta
     7141 caacgatccc gtttttactt gaacggctca ttcctgcaac taaagcaatg ggcgcagcta
     7201 gaatcagtgg acaaggtgat gccactacca gtacctcagc aaatcgtaaa gggtcttttg
     7261 agaaccacca agaaatacca ccgatcaaat aagcaatcaa cgtgaaaggg actgcataac
     7321 gatcagctaa acggacaaat cgggcaggct tttcttttga ttcttcgact agtttaataa
     7381 tcatttgata ctggctgtct gcggcacgtt tttcagcgat catttggatc gatccgtctc
     7441 catttaaaga ccctgacata atctgatctc caggtttctt ggtttccggg cgggactcac
     7501 ctgtcaaaga agattcatcg accgaagatt ctcctttggt cactcgacca tctgcgggta
     7561 caagttcgcc aggcttgact agtaactggt catcaatatt tatttcatcg attactatat
     7621 cctgcaattt tccttctttg aatcgatggg caattcttgg ggtgttatct aacaaagact
     7681 gcagttcttt acccgctcgt ttattcgcgt aatcctctag actatctccg cccgtaagca
     7741 tgatcaatat catcaaacta gcccagtatt ctttgacggc taatgttgca aggattgcgg
     7801 taatcgctaa tacatctacg ccatatcttc ctgaacgtaa cgtcttgatc atttccaaaa
     7861 acatcaagaa ggcgagaatc cctccagtaa atgcgacaat cgcaaatgca agggccggct
     7921 ggtgaaaaac aaattcactt aataaagcta tcccaccaat aagcaaagta agtaaaaatt
     7981 ttttgaaatg tgtcattgtt ttttctcctc ttttatgtga cttagagagg ttagtaataa
     8041 atttccagct gcctctttca tcttaagcat agtccttgac tagcactttt taaaacaata
     8101 ggccttaatt gaaaacaact atcactatca gcgtttccaa aattcatcag ttctacaaac
     8161 aaaaatattc agcaaggatt actttttcga ttcatcagtt aaaaagtacc ttttttcgaa
     8221 aaactatgct atacttttaa ttcgttattt acggcggaag gagcaaacat gcgatgaatg
     8281 agaaacaact agaacaaacg cacgtggatg aaacgatcga actaatccag atcgaacaaa
     8341 atatgctgga tacaaaacaa caagaattga ctcaggaaat gaatcattcg acaaaagaca
     8401 cagctaatca caagattcga gctggttcca atgaagcttt ttatgaatct gctgttgaat
     8461 atcgccaaca tgagcaggaa ttgcttttga aataccatac tcttgaagca cagcaaaaac
     8521 gcctgcaaac gttgtctgtc atgaaagata gtccttattt tgcccgtatc gactttaaag
     8581 aagaccgtga aacagaaaca ttatatctag gtatcgcttc tttaagagat ctggcagaag
     8641 aaacaatcgt tattgactgg cgcgcaccaa ttgccaatct ttattatgaa ggtgagattg
     8701 gtcccgcatt ttatgaaact gaaacagata gaatagatgt cgatctgcag ttgaaacgac
     8761 aatttaaaat ccaagaagga cgtattttat ctatggtaga tacgtcggaa gtaatcaatg
     8821 atgacttttt gctagagata ttggatgaat catcaagcaa ccatatgaaa aacatcgtct
     8881 ctacgataca aaaagcacaa aatgcaatca ttcgggacac aacaagtaaa gtaatgctga
     8941 ttgaaggaat cgccggaagt ggaaagacat ccgctttgct tcaacgtatt gcttttctgt
     9001 tgtatcataa tcgcaagtgg ctcgaggctg aaaacgttct tctattttca cccaaccatt
     9061 tgttttctga ttacatctcg actgtattgc cttcattagg tgaaagcggc gtgcctacac
     9121 agacattcaa aaattatttg gtgcagctgc tgccagagtt ttctttacta gatgaacagc
     9181 aacaagaaag tggttttttg ctaggggaaa aagatccgat acaagtgatg aaaagcggat
     9241 tgaccttagt cgatcagatt gatcgctata tccaaggcat cacaaactac ggtcccttgt
     9301 tccgtgatat gaaaataaat ggccgtacga tcctatcaaa ggaatcgatt cgccaatggt
     9361 ataaagaaac aaatgaacaa ttacctttac atcatagact ttctctatta caaacgaagc
     9421 tcctgaaaaa attaggcggt ctgcaaaaag acgaaacacg tcagcaatgg gtcaaagatc
     9481 tggcggaaga acagctccaa gaactatacg caacagatcc aaatcttgaa tatacagaac
     9541 aaaaggagcg ttcattacgt aaaaaactgg ccaaccaaat cgtacgtaaa agattccgtc
     9601 gaatccatcg agggatcatg aattatcaat ttgtcaatat aacgaaacaa tatctccact
     9661 ttctacaaac tgtgccactt tctcttctaa cacgacataa aatcagcgag accaggtggc
     9721 aggaacattt gacaactgtt cgtacacact tgcgtcaaag agaattgcgt caagaggatg
     9781 ctgtactatt ctttttactg atgcgccgaa catatccagt gacggttaca cacaaagctc
     9841 gctatatctt tattgatgaa atgcaggatt tcgcaccatc acaagtggca ttgctgcaag
     9901 ccttgttccc aaaagcaaat ttgactttct gtggagatct aaatcaaaat gtctttggaa
     9961 atgaaacgat cgttggatca ttggaagacc ttttcgtgga ccgtgaagtc actcgtttcc
    10021 aattaacgac aagctatcgc tccacaaaag aaatcactga ttttgctaat cattttattg
    10081 tgaaagaaca tcaagtagaa acaacagcaa gaaaaggaga ccttcctttg ctcatccaag
    10141 gaacaacaga tgatatcaaa ttgaattggt tagcagatac cattcgaacg actcagggaa
    10201 aagcccggta ttggcgtaca gcaatcatag ctaaaacaca agaagaatgc gaagctcttt
    10261 atgctcaact gccagacgag ttgaaacaac aagtccagct gattttaaat gagagtgact
    10321 ttatgaagcg ttccattatt ttacttccag cctttttagc aaaaggtctg gagtttgacc
    10381 gagttttctt gtgggatgta gatgcagaac atttttcttc tcagcaagac aaattgatcc
    10441 tttacaccat gtgtacacgt gcgatgcatg aattgaccct ttttacctcc aataatgaaa
    10501 gtcctttgtt aaacaatatg gatatttcat cttatgagaa aaaagtactg taagtaaaaa
    10561 gacaactgct atcattaatg ttagcagttg tctttttatt tacaataata attgcagaaa
    10621 aagtaattca atcatttaag gtcatttatt ctatatataa atccaaatct gtttcaggat
    10681 attttaattt gacaagcgaa ataatcattt tcagttcttc catgttttct ggatattctg
    10741 ggtcaaatac cttgctatga cggccaatcc cgccattgtc gatcaatcgg taaattcgat
    10801 tccattcaat gaattggtca attgattgga aattgctgat tggatagccg ccacaatcca
    10861 aaatctctga tacacgaaat gctaggtatg cactatcgat cactttattt tttttcgtgt
    10921 ctatcttctc atttctttcg ataagaattt tttcaggacg atgtttcaag ctccactcta
    10981 atagtagaaa gaaagcctcc atccgatact cttcttcaaa taaccgaaag gctgaatcag
    11041 aacgacgaaa aagcagcgga atcagataat tttgtctata aatcagcatt ggtgcgcggt
    11101 ccaccataca ctctaaataa cggttcagat accctgtacc gacatagttt cctaatcgat
    11161 agccttcaac gccgaatctt gcgtattttt gcgctaattt tgaacaatca gttacgttca
    11221 cagctaactc ttctactttg cggtaaccgc ttaagatacg ttcaaaaggt tctaaagtga
    11281 tttttgcttc catattcttc cccgtccatc ttccacatac ttcatatcat ttcacatgat
    11341 acttatgctc tcatcatacc acaggttgaa ttagaaaaga aaataaatca cacaaaaaag
    11401 caagacaatc tgttagtgag attgtcttgc ttttcgaaaa agactgaata cttttcgtta
    11461 aaactggttg cttagtcttc taatgccaca ttatggaaca catgctgtac atcttctaga
    11521 tcttccagtg catcaatcat tttttcaaat gtttcttgat cttctggaga tagtgttacc
    11581 tcgttttgag ggatcatttg gatctcagcg attgaaaaat cagtgattcc tttttctttt
    11641 aatgcttctt gtatactatg gaaatccgct acttcaccgt aaacgatgat ttgtccttct
    11701 tcttccatta catcgcgaac atcgatgtct ttttccatta ggtattcaag gatctcgtca
    11761 gcgtcttctc ctgcaaaagc aaagattgct gtattgtcaa acatgtaaga aaccgctccg
    11821 gaaacaccca tgttcccgcc atttttccca aatgctgccc gtacgtctgc tgctgttcga
    11881 ttcacattgt tcgtcaatgt atcaacaatc accattgagc cgcttggtcc aaatccttca
    11941 tagcgcaatt cagagtatgt ttcatctcct gcaccttttg ctttttcgat tgctcggtca
    12001 ataatatgtt ttggtacatt ataagtttta gcgcgatcaa tgacgaaacg tagtttttgg
    12061 tttgcatgcg gatcaggatc acctgatttt gctgccgcgt agatttcaat cccaaatttt
    12121 gcataaatcc ggctattatt agcatcttta gcagttttct ttgctacgat atttgcccat
    12181 ttacgtccca tattttcact tcgctttctg atttgatagt ttcataacgc aaaaacgtcc
    12241 tgttccatta tacttgtgaa tcacgattct gtgaagcttt ttttctttct tccttcattc
    12301 ttctcatttt tagtcaatta tctatactcg gattgggatt tgcccgaaat tctgttccgg
    12361 aatattgcct cccaattgat agatttgatc acttctaact aacagttccg cttcttgtgc
    12421 ctcttttttt ccgattcggg aataaataga aatctctttt ttttctttta agaatcttct
    12481 tccagcatcg gtaaatccaa gtagtcgaag ataattttta ttttgttgga caggaatctc
    12541 ttgctttttg atattcagca agacataaca agataatcgt tggatccgtg tccatgtata
    12601 tctttttgtt tttacctttg acacaaaatc ctcaaaacta tcagcagttg cagctgctgt
    12661 tttcatgcgc gattctattc cttcggtcat ctgatagata tctgtcagtt ccagcaaagt
    12721 agaagataac aaccgataac gcaaatacgg ccaataagat tcccaagtct gcagcgaaca
    12781 agttgaaaga tcttcttctg tctgaggcgg cacaagtcca gctattcttt ttccttcttc
    12841 taacgcatgg cgaatggctg ttgcactggc tatcctctga tctgtgatga ttttttcatg
    12901 atagcctgca cttttacgtc ggatcggatg taattccata gggtggacat acttggcatt
    12961 ttcctttgca taacttaatc ccaagatatg atttggcgaa gaaaaatcaa gcgtaatatc
    13021 gggatacaga ctgcgaaaaa cctcagtcat tttttgcgga taactatacg tttgatcaga
    13081 cagttcttga aatgcctctt ctatcctatc ttgattctct tggacaaagc gtccgaaact
    13141 gctgtaatca aacgaagtct cttcttctgt tccaaaacac aaactgtcac agtccagtgt
    13201 ttgcaagatt tttactgcac ctttagcaaa atagtcagct gactgaaccg cccattcgac
    13261 gggaagctcc actactaaat ccacaccatt ttgtaaagct tcattcgcgc gatgccattt
    13321 atcgatgata gccggttcgc ctctttgcaa aaaattcccg ctcattacag caatgacgac
    13381 ctctgctcct gttatttttc gtgccatttc cacatgatag cgatgtccat tgtgaaaagg
    13441 attgtactct acgataatcc cgcagctttt catgcgcatc ctccttcata gttatcgata
    13501 aaaaagaaat agagacaagt aaaaaaaggc aaaaatcgga aaaaataccc gaactatata
    13561 aactattctc gcaaacacaa tacttctgcg acgaaaagct gcactgcaag agcaatgcct
    13621 atatcgttcg gatatataat ttatgttgaa gatttattct tttcttgtta actcgagcag
    13681 gcaaaaccgc tagtctttgt atgctacaaa gaaccagcgc tttgatttct ctgatgctgc
    13741 ttcgtctgta aaatcagaaa atgcttcgac tttcgaaaag ccgctgtttt ccagcattct
    13801 taaataactt tccaatggat aggtacgctc ttgatgtagt tcatcttcac gaataaatcg
    13861 accagaccct tcttgttctt caacgaaaaa ggtaagaaaa tgttcgatgc tgtgtttctc
    13921 gcttcctgga taactatccc acaaaaaagc aaaattatcc ccttgataat gatagctata
    13981 ttctggaaaa acctcatcta cttgataggt ggagtgtacg tcaaataaaa atcggccatt
    14041 ttcttctaac gcttgataga cttcatcaaa cacttgctgt acctcttgtc tatttttcat
    14101 atagcacagc gaatcagaaa aacaggtaat tgcctgatat tgtccgattt ctgataaatc
    14161 gagcatattg ccttccacaa attggatcga tgcgtcttct tcatatgctc gctggctggc
    14221 aatcatcaac atctcttctg aaaggtctaa ccctgtcact ttatatccat cttttgcaaa
    14281 ggcaaccgct aatgctccag taccgcatgc cagttccaaa atattttttg tgtcttcttg
    14341 taaatgacgt ttcgaaaaag ctaaccattg ctgataaagt gtttcgtcca tcacttcatc
    14401 gtaaatgaaa gcaaatgttt cataagccat atgttaatcc aaccattcac taagatcgac
    14461 tagcggagca tctgaccata gtttttccag attatagaaa tttcgttctg gcgcatggaa
    14521 aacatgtacg atcacatctc caagatcgat caatacccat tttccgcctt cttttccttc
    14581 aatacgtttt acttcatatt tgttttcttc ttctttatca atgatttctt ctgtaattgc
    14641 gttgatttga cgttcgctat ttgctgaaca gatcatgaaa taatctgcca acaaggaaac
    14701 atttcgaacg tctaaagcga taatgtcttc tgcccgtttt gaatctgctg cttcaatcgc
    14761 aatttttaat tgttctttac tatctatgat gatttcctcc taatatgagc agcttatttt
    14821 tttgctaccc agtaattata tgtttcgatt gtttttggat aaatctgttg ttcttgcgca
    14881 agcaaatggg ccaatgtatg ttttgtttca aatgctacag cttcgtctag atcagcccat
    14941 gcaatggctc gtgcatcttg taccccagga aaatctcgac ctggttcaat atagtctgct
    15001 acataaatga ttttgtcaag gagactcatc ttagcagccc cagtcgtatg cacccggatt
    15061 gcatgaagaa tctctgcatc ggtgattcct aattcccgct ctacaaacga agcgccaaca
    15121 agaccatgcc agattgcatt attataattc aataactccg gatcaaaacc gtctcttacg
    15181 attaccattt tgaactcctc atctggtcgt tcttttgcat aatcatgtgt caatgcagca
    15241 atactagctt tttcaggaga agcaccgtat tttttggcaa gagccacggc tgtttcttct
    15301 actccaagca catgcttgaa gcgttgttcg ctcattctca tctgtatttt ttgcatcagg
    15361 ttttctctag aataagcagt atattcatta ctatagtcca tattcataca acccttcatt
    15421 ttgaatataa tcaattactt tatctggaac aaggtagcgg atagaacagc cttctttgat
    15481 cttttgacgt attttcgtgg aactgatgtc gatctcaggt acatctaccc aaattacagg
    15541 atatggagta tccgttgtgt atcctggtcg acgtataccc acaaagttga ccatagaagt
    15601 cagctcatcg attttatacc attttggcaa atattctacc atatccccac cgataataaa
    15661 gtaataatct gtatccggat tgttttgcgt caattccttc atagtatcat aggtgtaact
    15721 tttcccacca cgagctaatt caatcgtttc aatctgcaaa aaaggattgt cttccaccgc
    15781 taattccaac atgttgagtc gatgttttgc atcaatcgtc tgtttctcat caacatgagg
    15841 tggctgataa gaaggcatca aaaatacgcg gtcaagacct aaattccggc cagcttgttc
    15901 agccatcact aaatgtgcaa ggtgaacggg attgaatgtt ccgcccaaga tccctacttg
    15961 ctttttcttc tctaagaatt gaggcatttc ttcaggaaat aattgtgaac gaacaaatgt
    16021 cttagcttgc gtattcatca tggtcactcc ttatattgct tttacttctt ttgatagcct
    16081 ttgatacttt tcttttgtgg aaggtttgta taatacaata acacgtccaa tgatttggac
    16141 gatttcgcaa tctatttctt tttctaatac ttgagctgct tcttctgcaa tctcatctgt
    16201 attttgaagt aacgatactt tgatcagttc tcttttttct aaagcttctt caatttgaac
    16261 gatcattgct gaattgatcc caccttttcc gatttgaaaa atcggctgaa gatgatgcgc
    16321 tttgctacgt aaaaaacgct tttgttttcc tcttaaactc ataattttcc ttcttcctta
    16381 aatcaatgct ttgcgtttca atacatctac accctttggc gcccagcccg caattactac
    16441 tggcgctgtt acagtgatcc agcctagacc ggcaaaaacg atgtctgttt tttctttcac
    16501 agaaaactca aaacgaacaa gctccggaaa tgcctcgact tcatcaggac gaggaggctg
    16561 taataatcca cctacatgtt tttgataaaa ttcgtctgct ttttccagtt tcgttcgatg
    16621 aatatttaca tcatttgaca cataagcaat aaatgaagca cgattgccgc tgataaaatc
    16681 aaatcttgca agtccgccca agaaaagtgt ttgcccttca ttcagctgat aaactttagg
    16741 tttgatttct tttaacggtg caatgatccg caaatctttt ttacctaagt agtgcgccat
    16801 ttgatggcga tggataattc ccggtgtatc aatcaaaaaa tgcccgtcat ctaaaggaat
    16861 ctcgatttta tccaaggtcg ttcctggaaa ctgcgaagtt gtgattacat cttgtactcc
    16921 cgctgtattt ttgatgattt gattgataag cgtcgatttt ccgacatttg ttactccgac
    16981 gatatagaca tcccgtccat cgcggtattc ttcgattttt tctaatagtt ccgtcatctc
    17041 atgagatttc ttagcactag ttaataatac atctactgga cgaattcctg cttcgtaagc
    17101 acgttccttc atccattgtg ttaatttagt ttttttcaat gatttaggta atatatccac
    17161 tttgttccca actaaaagta ctggattgtc accgacaaaa cggtgtagtc ctgggattag
    17221 tgaaccattg aagtcaaaaa tatccaccac attgacgatc aatgcatctt tttgccctaa
    17281 ttcattcagt aagcgcaaaa agtcgtcatc cgtcaatgag acatcttggg tctcattata
    17341 atggcgtaat ctgaaacaac gctgacaata gacttccccg gaagctaaac ctttttccaa
    17401 agccgtttgc ggcgtgtatc ctaattcacc gggtttgttt gtttgtataa cggcaccaca
    17461 gccgatacat tgtaattctt ctgtcattcg attccacctc gccagcccat atcagggtgt
    17521 tttgctaata gataggccat aattcttttt tcccaaaaac gattaaattg tgtcttccaa
    17581 ctatctgttg cgataatggg ttttacaagg atgctacgta tccctgcacg attggctcca
    17641 cgtatatcag tcataatctg atcgcctacc attactatct catcatctgc taaatccaat
    17701 tgtttctttg ctatgttgat ccctcttgct aaaggtttca ttgctcgtgc aacatacaaa
    17761 agatcaaatt tttcaatcgc tcgcgcgaca cgttttgaat tattgtttga aacaacaaca
    17821 acagggattc ctgcattttt catttctaaa atccaagtaa gcaactcttc tgttccatct
    17881 ggattattcc atgcaatcaa cgtattgtct aaatcggtca atactgcttt gatgcctaga
    17941 ttctttaatt gggcaggtgt aatctgatag atggcttcta ccatccatgt tggtttgtaa
    18001 tttgaaaaca tgctgtctcc tcatctgcaa aaaatgaagg agcacataaa gtactcctca
    18061 accccgtatt atactgcata tcagcaaaaa aaactacctc tatactcgtt cgtctttcag
    18121 aaaaagcatt tctttacaaa atgaccaaaa ataaagattg atcacagaaa aatttagaaa
    18181 caaaaaacaa ctaatattgg tggaacctct tgtatcgttt ttccagtaat ttatgctgat
    18241 ctaatcgaac aagttccgtc aatctttcaa tcaacgcttt tttcataatg tgtgcgactt
    18301 tatatcgtgg caactgctcg ccgttgaacg tttcaggaat aactcgatca acgattccta
    18361 actcgcgtag ttctggcgca gtaattttca tcaactcagc tgcttctgcg gcgcgactac
    18421 cgtctttcca caaaatcgac gcaaatcctt ctggagaaag cacagcataa atcgtttctt
    18481 ccagcatcca gacttcatcc gctaaaccta gagcaagggc accgccactt ccaccttcac
    18541 caatgatgat ggcgatgatc ggtaccttta aatcagacat ttcgagcaga tttctggcaa
    18601 tagcctctcc ttcgccgcgc tcttctgctc ctacaccgca atatgcacct gctgtattga
    18661 tcaaggtaat caccggtcta ttgaactttt ccgcttgttt catcagtcgt aaagcttttc
    18721 gatagccttc aggatgggga gaaccaaaat ttctgcggat attttcctgc agatcccgtc
    18781 ctttttgaat accgatcact gttaccggtt tgccatctaa tcgagcgatt ccaccaacaa
    18841 tcgcttcgtc atctgcaaat aaacgatcac catggcattc ctcgaaagaa tcgaagatct
    18901 cttcaaaaaa atccaagctt gtccatcgtt ctttagctct tgctaactga acgacatcat
    18961 gtgctgtctt atccacgatc tatccatcct ttctgtgtat gcaattcaag aagcgtatgg
    19021 attttctgtt tcaattccat gcggggaaca atctgatcga caaaaccatg agataataag
    19081 aattcagcct tttggaaatc ttctggaagt tcctgcttga tcgtctgttc gatgacgcgt
    19141 cttccagcaa aaccgatcaa gctttggggt tctgctagaa taatatcgcc ttccattgca
    19201 aaactggcag ttactcctcc ggtcgtcggg tccgttaaaa cagttagata aaaaagacct
    19261 tcattgctat gccgtttgac agcagcagag atttttgcca tctgcattag agaaaagatt
    19321 ccttcttgca tccgtgcgcc acctgaagct gtgaacaaga cgactggaag actttccttt
    19381 gttgctcgtt cgaataatct ggtgatcttt tctccgacaa tcgttcccat acttcccatg
    19441 ataaaattag gatccatcac tccaataatg aagggaatcc cctgaatggt tgctttacca
    19501 gtgaggactg cttcatgaag tcctgtttta tcttgcattt ttttaatttt ttccgtatat
    19561 tcgggaaatg ctagcggatc tttggttaca agatccgtat cccattcttc aaaacttttt
    19621 tcatcaataa tcaaagctag acgctgccat gcaccgattc gaaaagcgta tccgcaatga
    19681 gggcatactt tttcttcacc gatgtctttc gtataaagga tatgtttgca atttggacac
    19741 tttgcccaca tgttatcagg aacagatggc gagttagcag gtttgctctc tctattagga
    19801 ttgatccgaa tatatttctt tttcttaaac agagccatct atgcgcctcc tatctccgtt
    19861 tctggtgtcc aattcggtaa aaattcttct tgtaaaaatg ctgtgctgta atcacctgct
    19921 atgactgcag gatgactaat caaatccatc tgaaattctg cgttcgtgat gattccttct
    19981 gtgataaatt cacttaaggc tcgctgcatc ttcattaatg cttcaaaacg cgtatttcca
    20041 tggacgatta tttttgcaat cattgaatca taatatggcg ggatcgtata tcccgggtaa
    20101 actgcactgt ctactcgcag tcccatccca cctgctggaa gcagtaagtt ttggatcttc
    20161 cctggagaag gagcaaaatg gaaagcagga ttttctgcat taatccggca ttcgattgcg
    20221 tgtccttgga atactacttc ttcttgacac acattcaaag gctcaccggc tgctatctcc
    20281 acctgttttt ttactaaatc gattcctgtg accatttctg ttactggatg ttccacttgg
    20341 attcgagtat tcatttccat gaaataaaaa tcgccttctt catccatcag aaactcgatc
    20401 gttccggcat tttcataatt gactgcttta gctgctcgaa cagcagcgtc tcctagtgct
    20461 tctctttttg tttgtgagat cactacagaa ggagattctt ccagtacttt ttgattgttg
    20521 cgttgtaaag aacaatctcg ctcgcctaaa tgaatgacat gaccaaatcg atcacctaag
    20581 atctgaactt ctatatggcg agcaggataa atgatttttt ccaaatacat atcatcattt
    20641 ccaaatgccg ctgctgcttc ttgctgagct gaagaaaaat gctgtgggag ctcttctttt
    20701 gattgaactt tccgaatgcc tttcccgcca ccacctgcag ctgctttcag catcactgga
    20761 taaccaattc tgtctgctat ttccaatgct tcttctactg tagataatac accagtactt
    20821 cctggaatga ctgggacatt tgcttcttgc atcaattgac gcgcattgat cttatttccc
    20881 attgcatcga tcgttgcact tttaggacca ataaatgtga tattgcactc ttcacacatg
    20941 gaggcaaatc ggctattttc agataaaaaa ccaaatcctg gatgaattgc ttcggctttt
    21001 gtcacgattg cagcgctcag tacttcctga acattcagat atgaatcaac ggcttttgcc
    21061 gggccaatgc agattgcttc atctgctaac tgtgtatgaa gtgcttcggc atctgcttct
    21121 gaatatatcg ctacggtttg gatccctagt tcgcggcatg cacgaatgat acgtacagcg
    21181 atttcaccgc ggttagctat caatacttta gaaaacatat ttcacctatc caatcataaa
    21241 ggttaattcc gcttcggcta cttttttacc gtctacttta gcgattcctt tgcctattcc
    21301 ggctgaagct ttcactttca atatctcaac ttcaaggtat aaggtatctc ccggtgtaac
    21361 tttcttacgg aattttgctt tgtccaatcc gccgaaataa gccgtctttc ccttgaattg
    21421 ttcaagagaa agtaatgcaa ctgctcctgc ttgagccatt gcttcaacaa tcaatacccc
    21481 tggcataaca ggttcttctg gaaaatgtcc ttgaaaaaag ggctcattga tcgttacatt
    21541 tttcttagca acgatccgtt ctccttcaac catttcttcc actcgatcaa tcaaaagcat
    21601 tggataacga tgtggaatga tttcttttat ttcttgtatg ttcattgttt tccctctttc
    21661 ctgctttgct tatttttgct gaatcctaaa gagtggctgt ccatattcga caactgactc
    21721 gttttctaca aggatttctg tgatcactcc gtcggcctca ctagttatct cattcatcag
    21781 tttcatcgct tcaataatgc agataacttc tcctttggca acttgatcac ctactttttt
    21841 gaaagctggt ttgtcgggcg ctggttgcag ataaacgatt cccacgattg gcgaaacaac
    21901 ctcgattcca tcaaatactg ccgattcttt ttctttcatt atttctggag cagttgttgc
    21961 ttgttcaggt atgacattga ctggctccga aactggcaac gtttcgtttg tttgaaccat
    22021 attcatgcct cgacttgttt tatttttatt catatacaat tcaaattgac cttcacgcaa
    22081 atcgaattcc gttagcgagg attgatcaaa ttgactgact aattctctga tttcattgat
    22141 atccaaaatt attcctccca gcgtttcatg cacagaaccg cattatgtcc gccaaaccct
    22201 aatgaattac tcattgcata agtaaaactt gcaggtttgc tttcgttttt gacaactgtc
    22261 aagtcaatct caggatcttg tttttctaca ttgatcgtag gtgggataaa ttgatgttct
    22321 aatgccagca aagttgccaa ggcttcgatc ccgccggctg ctcccaataa atgtccagtc
    22381 atcgatttcg tgctgctgac gtaagtatct ctgaaatttt cacctaatgc gatttggatt
    22441 gcttttgctt ctgcctggtc attggctggt gtacttgttc cgtgagcatt gatatatccg
    22501 acttgttccg gctgtacacc agcttcttcc atcgcaagct tcattgcttt agatgcacca
    22561 gaaccatctg gagtaggagc tgtcatatgg taagcgtcac agtttgcacc gtatccaacg
    22621 atttctccat agattttggc accgcgagct tgtgcatgtt ctaaagattc aagaactaga
    22681 acgcctgctc cttcacccat cacaaaacca ttccgatttt cgtcaaacgg aatcgaacca
    22741 cgattaggat cagttgattc tgagagtgct gttaaagctg caaatccagc aatccccatc
    22801 tcacaaatcg ttgcttctgt tcctccagca agaatgacat cagaatagcc atgtttgatg
    22861 ttacggaatg cttccccaat tgaattcgtt ccgctagcac aagctgttac gatagctgta
    22921 caaatacctt ttgcacctac acgcaaagca atatttccag ctgccatgtt ggcaatcgcc
    22981 attggtacga acattggaga aactcgtttt gcaccttttt catgtagacg aataacttgg
    23041 ttttcgattg ttggaagacc accgatccca gatccgatga tgacgccaaa ccggtcttga
    23101 ttcatttttt ctttatctaa accgctcatc tccattgctt ctaaagcagc gtagattcca
    23161 tagatcgaaa acatatccat tcgtttgcta tcttttttaa taaaatattt atcgtaaggg
    23221 aaatctttga cttcacccgc taaggtaatc cctgtttctg aagcatcaaa tttagtgatc
    23281 ggtgcgatgc cattcgtccc ctcttttaag ctattcaaaa agctgtctgc gtcatttcca
    23341 ataggtgaag tgactccata gccagtaatt accactcgat tcatttgttt gctctccttt
    23401 tcttatccgt gcatgaccaa tccgccatcg acattgatga cttgtccggt gatatatgga
    23461 ttttgtgcta agaaaactgc tgtttgtgca atatcttcta cttgtccgaa acgctgcatc
    23521 ggaatttgct tttccgcttg ttccttgact ttgtctgcta aaacttccgt catatcagtt
    23581 gtgatgaatc ctggcgcaat ggcattacat gtaatgcctc tagttgcagc ttctcgtgcc
    23641 acagattttg ttaatcctac tacgccagct ttactagctg cataatttgc ttgaccaata
    23701 tttccaatca acccagatac actagagaga ttaatgatgg ccccttctcg ctgcttcatc
    23761 atttttttca atacgtgctg cgtcatattg aaggttccaa tcaaattgat atccagacat
    23821 tttttgaaat cttctgcatc cattcgcatc acaagtttgt catttgtgat tccggcattg
    23881 tttactaaca catggatcga tccaagcttt tcttctgctt ctttgatcat ttgtcccgct
    23941 ttctcataat cagagatgtc accggaaact cctacgcatt ttacaccgaa tgcttcgatt
    24001 tcttctatct tttcttttgg aatctctccg cgaccattca aaatgatatt tgctccagct
    24061 tttgcaaaag ctaaggccat cgctttgccg attcctcttg tactacctgt gataaataca
    24121 ttttttcctt ttacatccat aacgttcctc cttatagtat tgctattgtt tcatcaaatg
    24181 tctgcttatt ctcaacacgc agaactggta ttgttttatc gatttttttc ataaatccgc
    24241 ttaatacttt tccggggccg acttcgatga cttgttcgat gccgattgtt tttaacttat
    24301 ggatactctc atagaaacga acaggttgca tgacttgctg ttcaagtagt cccgcgattg
    24361 tttctttctt cattatttcc gttgttgtgt tgcttatgat aggaaaagaa ggttcagaga
    24421 attgaatctg acttaggtcc ttcgccagtt tttttgctgc cggttctaaa atagctgtat
    24481 gaaaaggccc gctgacattt agagggatca ttcttttgaa ccctttttct tttaatagta
    24541 aaacagcttc gtctactgct ttttcttcgc caccaatcac gatctgctga ggtgtattat
    24601 aatttgcagg agatacgatg ccgtacttgc tagcttcatg acagctttcc tcgatcgttt
    24661 caatcggcgc attcatcact gcaaccattt tcccgcttcc agctggggca gcttctgtca
    24721 tataagcgcc tctttttgct actaacgcaa ctgcttcagt gaaggatagc gcattactag
    24781 ctactaatgc cgaatattct cctaaactca gtcctaaagc tgcatctggg atgattccat
    24841 gctccttcaa taagcgataa tacgcgatgc tgactgttag aatagctggc tgtgtatatt
    24901 gcgtctgatc caaacgttca ttttctgtaa agcaaagttc agccatatcg tagccgagaa
    24961 tctcacttgc ttcatcaaat gtctgcttta caacggcttc ttcatataaa tcttttccca
    25021 taccttgata ttgtgcacct tggccactaa ataagaatgc tgttttcatg tttttctcca
    25081 atatatccag aatatatgtt tgattcttcc tattcaaaaa ggccgagaca ttcctatttc
    25141 aggaaatgtc ccagccccca acctaatttt aatgattatg cagtttgttt ttctacgtaa
    25201 gtcactaaat cttgaaccgt tttgattccg tcttctgttt cgattttcac gtcaaattca
    25261 tcttcaattt cattgatgat ttggaataaa tccaagctgt cagcttctaa gtcttcttgg
    25321 atgtcagtag tcaatttgat ttcttcagtt tcttttccta attcttctgc gatgatttct
    25381 tgaatttttt cgaataccat aataatatat tcctccgata ttgtttgctt tttattttta
    25441 taatttaaca gtctacaact ccatgagaat acttccccat gttaaacctc cgccatagcc
    25501 tgtaaatatt actttctgct gttttcctaa ggtgatcttt ccactagaaa ctgcttcatc
    25561 caataagata gggatgcttg cagcagatgt attcccatat ttatccatat tggtcaggaa
    25621 cttttcttgc ggcatcttta cttttcgggc aattttctca ataattctga ggtttgcctg
    25681 atgcaaaagc agataatcaa ctggtttgtc tttcatgact tcttggatat tgtttgcaac
    25741 gtctcgtacg gcaaaatcaa aaatatctct gccagtcatt tgcaaataat acgaaccttc
    25801 tgaatcttct gaatagaacg gatttttatt ttgctggtag ccagcggtca atgagctact
    25861 tctggtaccg tcagctgcta atttttcttt cagcaatttt ttctgtggat tcgcttctaa
    25921 gagaatccca cctgctccat cgccaaacaa cacagcagtc gtacgatcag accaatcgat
    25981 tagcttagat agtgtttcac caccaatcac cagtccctta gttgagccgc agcggatcat
    26041 tttttcagcc atgcttaacg cataaacaaa tcctgagcac gcagcactga tatcaaaagc
    26101 gatagcatga gttgctccca atttcccttg tacttgtgct gctacagatg gtgtcgtgta
    26161 atcgggcgac attgttgcta ctaaaataaa atccaaatct ttagggttta gatttttctg
    26221 ttttatcaat ttttccgcca ctaaaatgca taaatcagaa gtctcctgat ttgttacaca
    26281 tcttcgttca cgaatacccg tccttgacga aatccattca tcagaggtat ccatcatctt
    26341 ggaaagatca ttattagtaa taatcttttc aggaaggacg ctggctgttg cagtaatcat
    26401 tccaaattgt tccattaaat atcctcactt atagtcttgc aagaagtcgt gcaagttttt
    26461 cagtgcatcc agcaaggcat gctgttcctc cgtagccatt ccgtctaaga tgttcttgac
    26521 catttcacga tgaaaatgct gatggacccg aaatagtaac tttccttttt tcgttagtcc
    26581 caactttaca acgcggcggt catcttcact gcggatacgt tcgacatagc ctttttttac
    26641 taacttgtta atagcagtgg tcaaggtccc aacagtaatt gatagttctt tggctacttc
    26701 tgaagttgtt tttttcttgt acatcccgat tgcctcgatc gtgtgcatct ctgtgattga
    26761 cagatctttg aattgagatt ttttcagctc agactcttcg attgtcaaaa tatcattgaa
    26821 gacactaaca agataatcat ttactgtttt taaatctggt tccatgttcc accgtccact
    26881 aattagtttg attatcaaat cttttgatgt tcaaactata tcttaacttt tttcaaaatg
    26941 caaccttaaa agatcatttt tttactatat gagctttttt taagatttta ctcatttaaa
    27001 acaactgata aatcagcatt tataatttct tttattagaa aaatcatcta tctcacatat
    27061 tttgattatc aaagtatttt ctgtgaacag aactatagaa ttccctaaaa cttgtccatt
    27121 atttcaaaat ttgttatagt ctttttattc aaagcgtaaa aggagatcct atgttaaaag
    27181 aaaaaatgaa aactctcccc atgctgccgg gtgtctatct tatgaaagac cgagatggta
    27241 aggtcatcta tgttggtaaa gcaaaacggc tcaaaaatag agtaagcagc tattttcatc
    27301 agaataaaca gcattcaaaa aaagtattac gtatgattca tcatataaca gattttgatt
    27361 tcgtcgtagt agacacggaa ttagatgctt tattgctcga gtgtcaattg atccaacatt
    27421 accgtccttt ttataaccga caaatgaatt atttcagtaa ttataattat gtacatatta
    27481 ccaataaggg atttgtatta acagatactc ctacggctcg aacatacggg ccttttcgtc
    27541 tctataaaaa aatgccgtct attttgcgta taatggaaga aacttatcaa atgccttggt
    27601 tgtctgaaat tagtttgtta gctttgcgag tccagcttcc tgacctacag gaaatgactt
    27661 ttgaacagaa aaaaaaggaa ctccaagggc tgtttcaagg ccgaaataaa aagctactga
    27721 cttacttgaa aaaaagacaa caacatttca tctatcagtt gaatttcgaa aaagccggta
    27781 tgcttcaaaa agatatcgaa ttagttactt attttattag acggatccag gaacaaaagc
    27841 agtttttaag aacaccatcg ctcaccttca gcatgccatt agcagcagat gagagtcaga
    27901 aaaagcacta cctcgtttgt tatggtcaac ttgcagaaac aatgattacc tctggtgacg
    27961 tttctcctga cttctattat gaaaagaaag aagctcattt atctttgaaa cgtcaattgt
    28021 caaaagaaga aatcgatcct gtacaaatct tgatcagtta ccgcaaaaaa ttagaaaaag
    28081 aacagtttga aattgaactg ttaaacaaaa aagaagctga aaagcaacta aattagttgc
    28141 ttctcggctt cttttaggca tcttcaactt caaatgtcaa ttatcctaaa atttattgga
    28201 ttaagtcata gatttccatc gctacgatat cgatattatc aaattcgtat tgctgatgag
    28261 tatctgtttc agttaattca aatgtatcgg tcgctttatc ataagttact gtacacttct
    28321 ctacgccttc tttttcaaaa cggcgaactt gcagttcatt atctgctgac tcgaccatag
    28381 cctccagtcg ttttatgatt gcgactaatt gtgaatgtgt catcggaggt cctccttttc
    28441 ttatttctgt tatattgtat caaaagcata gcctacttgc attgattttc tctaaaaaaa
    28501 ctcgtttttt atgatttttt ttctggtatt tttccttcag gccaccaaag tttgatcaaa
    28561 gcttgggttc cgtcattctc aaaaccttta tctgccaact cttcatatag tttcaatgct
    28621 tgggtagttg ctggcaatac aagatccatt ttttctgctt cttctaatgc aatctttaaa
    28681 tctttgataa aatgtttgac aaaaaaacca ggtgtgtaat cttcttttaa aatacgagga
    28741 gaataattgc ttaaagacca gttagctgca cttccacctg aaagcgtctc aatcactttc
    28801 tttaaatcaa gtccgttttt ttgtgcatag acaagcattt ccgtcattcc tgtcatcgta
    28861 cctgcaatca tgatctgatt agccattttt gtatgctgac ctttcccagc agaaccatgc
    28921 aatgtaaatg tcgtaccaaa ttctttgaat aaaggcagta cttgatcata aacggcttct
    28981 tctccaccga ccatgatcgt cagtgtacca ttctttgctc ctaagtcacc accggatacc
    29041 ggtgcatcta acgcatctgc gcctttttct tttgctgttt ttgcaatttt ttctgccagg
    29101 ctggtgtact tgtagtcaaa tcaactaaaa tatgtcctga gatatctgca gaaaaaatcc
    29161 ccgactgtcc atagtagatt tcttctacat ctttggggta acctaccatt gtaaagagaa
    29221 tattactttg ttctgctacc gcttttggtg tatctgccca gatagctcct tctgttacta
    29281 aaggatcagc ttttgctttt gtccgattat agacagctac ttcgtgtcct gcttctagta
    29341 gatggcgtgc gacagcactt cccatgacgc ctgttccgat aaaaccaagt ttcatttttt
    29401 cgacctccta aaaatcaaaa atccttgctt ctatgctagt atacgctaga aacaaggatt
    29461 ttttcataaa aaatgtttga attttatctt ttaaatgaat ttaattttat tttgattcgt
    29521 tcaatcgagt cttcttcttc ttttcttcgc atctcttctt catgataaac aaccatgtct
    29581 tgataaaatt cgatcatagc ttcgccgaaa tgtgtagatg aaatatcata aagtttagct
    29641 tctaaaactt ttggatcttt aggaacttca ctggaaatat aatcaataag tgctggtgca
    29701 aagtcttcgt cggtttcaaa agttttccct aatgaaggat gatcgaacaa tcggttcaaa
    29761 taagcatttc cttccacgac acaaggtgtt ccggctgcca tcgcttctgt ataagtaagc
    29821 ccttgtgttt ctgaagtaga agcactgaca aaataatctg ccgctttata ataaagtgct
    29881 acatcattgt tgtccacttc tcctgtgaac tgcacaaatt cttctaactg cagttctgag
    29941 atcaattcct ctaactcttc tacataaggt ccttttccta cgataactaa tctggcgtta
    30001 ggataagcgg agatgacctg aggaaaccca ttaatcaagg cttggatatt tttctcataa
    30061 gaaatcctgc ttaaagaaag aatcatcaaa tggttttcct gaagacctag tgactccctt
    30121 aatttgctga tatcctgctg agtgatatca gaacgtttga atttttcaat gtcgatacca
    30181 gtaggaatca cgcgaagcgg tgctattaca ccatagctgc gtaatgtatc aataacacgt
    30241 tcacttggac aaactacacc tgtcgtatga tttgcaaata atctagacaa gtattttaca
    30301 tgggattgcc tgatcacttt tcctttaccg atataatgaa ggtagtcttc atacatcgta
    30361 tggtaagtat ggatcagagg tattttcaac ttcttagcta ccatcttccc aagtatccct
    30421 gctccgaatt ctgtatgggt atgaataaga tctagttcta gttctttggc aaccaaataa
    30481 gcataccaca tgcctctaac aacaactctt cgatccttga aagaaataaa tggtacactt
    30541 ggcattcgaa tcacatcttt ttccaactta tccgcattag gatcggtcgt tgtaaaaata
    30601 tagacttcat gcccatgtct ttctaattct tgttttaatg ttttgatcga tgtagcaact
    30661 ccgctgactt gcggaaagta ggtatcggta aaaaagccga ttttcatgtt tttcgcctcc
    30721 aaactagtcc ttgacctgat ttactttttt taatttgcta gagacttttt cattcagtac
    30781 actttcgtat acatttttaa gttcttcacc gattttattg atacttcgct cttttgctgt
    30841 ttgataaccg gcttgtgtcg tactcggtag ttcttgattg gtaatctgtt ggatcagtcg
    30901 gataaattct tcgtttgtct tccccatata gcagttcttg ctatcttcta accagccatt
    30961 atacactgga atatctcgaa caagtacgtt ttgtttgctt gctaaagctt ctaaaacaac
    31021 gatcccttct gtctcttcat aagaagggaa aaagaataga tctgcacctg aatacgcacc
    31081 ttctatgatc tctccacgaa tgtaaccagg aaacaggaca ttttcaggat gatcttcttt
    31141 tacaattttc cggatgttcc gaggaatcga gtacatggga acatgaccaa accaaataaa
    31201 tgtgtattcg ggcatcttct tagcaatttc tacgaaatca atgattcctt tacgttcgaa
    31261 aaacaaaccg acacaaatga ttactttttg atccggagac agtttgaaat attctctgaa
    31321 cttttgttct ttcattggat cagggtgata tttctctaag tcgatcccat tggaaatagc
    31381 ttgaatcggc acacggatac catagctttc caacaactgt tttgaataag gtgttggcgt
    31441 gatcagatag tccgcttttt ggtacaatcc taccagatat ttttttacga taggagaaag
    31501 ctggttcgat ctgataaagg aatttcggaa atcttcctct gtagaatgcg catgatagac
    31561 aacttttttt ccttctcttc tggctttatt gaccatatta tgactattga ttccgtatgt
    31621 attgatgtgc aggatgtcat aatcttcttt ttcatctagt gtataagaga taccgacttc
    31681 cgtcagagca cgtttttgat gatcaagcgc acgcccgatt ccagattttg caagcatctt
    31741 ttcactttca aaatataata ataccttcac cttacgtccc ccttcactta tatagtataa
    31801 catagcctac aaactgtcac tcaaacttaa gccctatttt tgtctattct tactgacaaa
    31861 aacgttttct taaaaaagaa caaaaaaact ggcgtagctc ttttacaagc cacaccagct
    31921 tttgatacgt tgtttatttt acatattcat gaacaagttc aacgacttct tccatcatat
    31981 cgcattcttt caatgcacga tcagcaagtt cagccatttt cgctgtgtcc aagcgtttca
    32041 ttaaactacg cgttttaaga atagatgtcg cactcattga gaactcatct agacccatac
    32101 ctactagcaa tggaacagct gtttgatctc cagccatttc tccacacata cctgcccatt
    32161 ttccttcagc gtgtgctgca tcaattacat ttttgatcaa acgtaaaatt gatgggttat
    32221 atggttggta caagtaagaa acgcgttcgt tcatacggtc tgctgccatt gtgtattgaa
    32281 tcaaatcgtt cgtacctaca gagaagaaat ctacttcttt tgcaaacttg tctgctaaga
    32341 ctgctgctgc tggaatctcg atcatgatgc cgacttggat cgtatcagat acttccttgc
    32401 cttcacttat caatttttgt ttttcttctt caaagatcgc ttttgctgcg cggaattctt
    32461 tgagtgtagc taccataggg aacatgatac gtaaattacc atgaacagat gcacgaagca
    32521 atgcacgcat ttgtgtacgg aacatttcgt cgccttgttc agataaactg atacgcaatg
    32581 cacgatatcc taagaatgga ttcatttcat gaggtaattg cagatatggt agttctttat
    32641 ctccaccgat gtccattgta cgaacaacta caggttttcc ttccatacct tctaatacag
    32701 ctttgtaagc ttcatattgg tcatcttctg ttgggaagtc tggagaatcc atatacagga
    32761 attcagtacg gtacagacca actgcttctc caccattatt atggacacca actagatctt
    32821 ttggtgttcc gatgtttgca gctaattcaa aatgcttgcc gtcagctgtg acagtttctg
    32881 cattttttaa tttttcccat tctgcttttt gtgctgcgta atctgcacct gctttttcaa
    32941 attcagcttt ttgttcatct gtaggatcga tgattacatc gccttcgatc ccgttgacag
    33001 ccaaaatatc gccttctttg actttagcag taatttcttt tgtcccaacg attgctggaa
    33061 tttctaaaga acgtgccatg atagcagaat gtgaagtacg tccaccaatg tctgttacaa
    33121 acgcttttac aaaattgcga tctaattgtg ctgtatcact tggagtcaag tcatgtgcaa
    33181 caacgaccac ttcttcgttg atcattgatg gatttggtaa agtaacgcct aataagtgcg
    33241 ctaaaatacg tttagcaacg tcacgaatat ctgcagcacg ctcttgcata taagcattat
    33301 cttccattgc ttcgaacata ccgatataca tatccgttac ttcttttagc gctgattcag
    33361 catttacgct gttgtcttta atattttgct tgatttgacc taccatttct ggatctgaaa
    33421 gaaccatcaa atgggcatca aatacttgcg cttctgcttc acctaagctt tgcgctgctt
    33481 tttcacgaat ttgctgcaat tcttcagtag atttagctaa tgcagcatcc aaacgagctt
    33541 cttcagccgc agtatcttct actgttgcct tactgaatgt taaatccggt tgaactagca
    33601 ggtaagcttt tgcaacggct acaccgtcac tagcggcaat cccttttagc atttcaacca
    33661 ttattcagat aagccttctt tcttcattgt ttcaacgatt gctgccattg catcagcttc
    33721 gtcagcacct tctgcagtaa tagtaacatc agaaccttga cctacaccta aagacataac
    33781 gcccatgatt gatttcaagt ttactgattt acctttatac tctaagttta catcagagtt
    33841 aaatttgctt gctgtttgta ctaatagtgt agctggacga gcgtggatcc cagtttctgc
    33901 tactacgtga aattctttct tttccatatt aatcggtctc ctttaagtga gtgttgtttt
    33961 tatgtgaggg ttttcttttt tagtaattca gagaatccta acaaatgcca ccctttcatc
    34021 tgtaaagatt aacatttttt ttcgttagat acaacagttt tcattcaatt tcagataaaa
    34081 gtattcaaat tattccggat tctttttcat ccttttcttc acattttata acaaacgtgt
    34141 ttatttcctt tttcttgtcg ctttctcttc tcctgacgtt tatcattctt tcctttgacc
    34201 ctctttgttt tcatatgaaa cgaattactt gcttcccttt ttatttttag tataataaga
    34261 gtcaaaggtc aggaatggtc aatagagatt tcaccttttc tacctcataa atctcttaaa
    34321 aaactagggg ttattctttt acctcatgaa aaacgagatg taaaatatgg atgtacccat
    34381 ttttgtgaaa ggacgtgaat gattcatgct ttgtcaaaac tgcggcaaga atgaggcaac
    34441 gattcacttg tatgccactg tcaatggtca gcggacacaa ctcgattact gtcagagctg
    34501 ttatcaaaaa atcaaaaatc aacaaaatgg aggtctgact aatatggccc aaaatgatcc
    34561 atttggattt ggcagtttgg acgatctttt ccgttccatg tctcgccaaa tgcaacagca
    34621 aggaaattat gagcaaacac caccaacaca atttggcgga aacaacaact tcaatggtgg
    34681 tcagccacct caaggcaata cagaaggttt attgggagaa tacggaatca atatcacaga
    34741 acaagcacga caaggtgata tcgatcctgt gatcggacgc gatgacgaaa tcaaacgagt
    34801 cattgaaatt ttaaatcgcc gaaccaagaa caatcctgtc ttgattggag aaccaggtgt
    34861 tggtaaaaca gcagttgttg aaggtttagc acaaaaaatc gtagatggtg atgtaccgca
    34921 aaaattaatg gacaaagaag tcattcgttt agatgtcgta tctttagtcc aaggtactgg
    34981 tatacgagga caatttgaag aacgtatgca aaaattgatt gaagagatcc gtcaagcaga
    35041 aaatgtgatc ctattcatag atgaagttca cgaaatcgtc ggtgctggtt ctgctggtga
    35101 tggaaatatg gatgctggta atattttaaa accagcttta gctcgaggag aattgcaaat
    35161 ggttggtgct actaccttaa atgagtaccg catcatcgaa aaagacgctg ctttagaacg
    35221 tcgtatgcaa cctgtacggg tagatgaacc aactgtcgaa gaaacgatca gtattttgaa
    35281 aggtttgcaa aaacgttatg aagactatca tcatgtaaaa tatactgatg aggccatcga
    35341 agcagccgca actttatcca atcgttacgt ccaagatcgc ttcttgccgg ataaagccat
    35401 cgatttgcta gatgaaacag gttctaagaa aaacttgacg atccaaatcg ttgatcctaa
    35461 aacaatcgag aaaaaactgc aagaagcaga agaacaaaaa gttttagctt ctcgagaaga
    35521 agatttcgaa aaagcagctt attatcgcga tcagatcaat aaacttcaaa aaatgaaaga
    35581 acgtcagctc actgaagagg aaacacctgt gattaccgaa aaagatatgg aaaaaatcgt
    35641 tgaacaacgg acaggtattc cagtgggtga attaaaagaa aaagaacaga cacaactgaa
    35701 aaacttagca gatgacttga aagctcatgt catcggacaa gataacgctg tagatcgagt
    35761 agcgaaagcg attcgccgaa accgtgttgg attaaacaaa cagaatcgtc caatcggctc
    35821 cttcttattt gttggaccaa ctggtgtagg taaaacagag cttgcgaaac aacttgccta
    35881 cgaactattc ggttcacaag attcaatgat tcgtttcgat atgtctgaat atatggaaaa
    35941 acatagtgtc tctaaattga ttggttctcc tccaggttat gtcggatacg aagaagctgg
    36001 tcaattaaca gaaaaagtac ggagaaatcc ttacagtctt gtcttgttag atgaagtaga
    36061 aaaagctcat ccagatgttt tgcatatgtt cttgcaaatc ttagatgatg gtcgattgac
    36121 agatgcacaa ggaagaacgg tcagctttaa agatacgatc atcattatga caagtaatgc
    36181 cggaactggt aaagtagaag caaacgttgg ttttggtgcg gcacgcgaag gtgttactcg
    36241 ttctgtattg aaccaattaa acaactactt tacaccagaa tttctgaacc gttttgacgg
    36301 gatcatcgaa ttcagtgcat tatcaaaaga aaacttgatg acaatcgtca cactaatgct
    36361 agacgatgtc aaccaaatgc tggcagcaca gcaacttcac atcgaagttc ctacgaatgt
    36421 caaagaaaaa ttagttgact taggctatga tccatctatg ggtgctcgtc ctcttcgacg
    36481 cacgatccaa gaacaaatcg aagatggtat cgctgaattt tatcttgatc acccttctat
    36541 ccatgagttg aaagcaaaac tggataaaga tggaaaaatc atcgttactt ctaaaccaga
    36601 acgtttggct aaagaatcag ccgaagaaac ggctgaataa atccagtttt atagcgtgag
    36661 acggtatttc tttgagaaat gccgtctcat tcttttttca gaaaagtcaa aatactgttc
    36721 attttataaa aaagaaatta taataagaga aacaagcaat taaaaataca taaaagaggt
    36781 gagcgccatg aaattggtaa atgtaacaaa cagccattcc cgtcttgtat taaaccagct
    36841 tgaaaacact gatgcccatc tagtcaaggt ctacacagcc ggaaatacca ctattgtcta
    36901 cactgaagcc cctgaacata atgaaattct gctgatcaat gacaaacgta aaatccagcc
    36961 gaaagaaatc gaagatgcta aaaattattt cttagataaa atcaaagacg ccgtttacca
    37021 cgaggatgaa atcaaagtaa tcgaattggc aggccttgtt gaaatctcga ttccaaaaca
    37081 tgaattaggc gctacattag ccgtgtaaac aaattttgaa cataataatt aaagagcgtg
    37141 ggacaaaagt aaagaacact tttgtctcac gctctaaaca cgtataaacg gcgaaagcag
    37201 aagcaactcc ttcggaaata agctgaaatt cacgaaaatt gcttttcaaa tttttgtgaa
    37261 ttccagctta tttcttggag ttaaacgctt ctgtctcagc ctctttttct ttctagcttt
    37321 ttgatttttc tcttttcttt tgtacttttc tcttttcatt ttcagttcta cgcgtgtctt
    37381 tatttttaac tttttcctct ttatggatga ttgatcgtac tttttgtgca atttgctcgt
    37441 ttttgtccca gtcttttaca tctaataatc gacataatcg taacatctct tcttttttct
    37501 gtttttttct ttcacgtctt tgccattctg tttccatgtg tcacactctc ctttctttaa
    37561 tcatatgtac gcaaaataat ttttatattt ttttgattag acatttctat gattttaata
    37621 tagtaaaaag agccgtcacg gaaaatccgt cacggctcta aacaaaatat gagaggctgt
    37681 ttttgtttgg ctattcttat tacttgatgc agggcagctt gtgtcaagac ttctttacat
    37741 caaacttttt aattttacat tgggatattt atccgcaaac cagcgttctg caaattggtt
    37801 ctcgaataag aacaacggtt ggtcgaaacg gtcacgagcc aagatattgc gacttgaact
    37861 catcttctca tccaaatctt ctggatcgat ccagcgagcg attttgtgtc ccattggaga
    37921 catgattact tcggcgttat actcatttaa catacgatat tggaatactt cgaattgtag
    37981 ctgaccaaca gctccaatga tatattcttc cgttagatat gttttataaa gctgaatcgc
    38041 tccttcttga actaattgat agattccttt gtggaaggat ttttgtttca tgacattttt
    38101 tgcagtcact ttcataaaca gctctggagt aaatgaaggg agttcttcat aagcaacttt
    38161 tagttttcct tcgaacaatg tatccccaat ctgataattg cctgtatcat atacaccgat
    38221 gatatcgcct gctactgctt tttcgacgtt ttctctcgaa tctgccataa attgtgtgac
    38281 attgcttaat ttcagttttt tatttgtacg ttccaaccag acatccattc ctcgttcgaa
    38341 tgttccagaa cagattcgga caaaagcgat tcggtcacga tgggctggat tcatatttgc
    38401 ttggatcttg aatacgaaac ctgaaaattc ttcctcataa ggacttacca tctgatcatc
    38461 ttgtgttttg tgtccataag gagctggtgc caattcaacg aaagtctcta aaaaagtctg
    38521 tacaccgaag ttagtcaatg cagaaccaaa aaatactggt gtctgatcgc cacgagcaat
    38581 tttttcttga ttaaatgcat ctccagcctc tttgattagt tctacttctt ctaagacttg
    38641 ttcatataag gaattttcag ttagaggatg attttcggga agcagtccat cttcatccaa
    38701 ttctactaat cgttcatcct gataattttc cggacgataa aactctacac gattatggta
    38761 gatatcataa agaccttcta gccctttacc cataccgatt ggccaattca tcggataaga
    38821 ttcgatatct aatagctctt ctaattcttc taacaattcc aatggttcac gaccatcacg
    38881 atctagtttg ttgataaaag taaatatcgg gatgccacgt ttttttacaa cttggaataa
    38941 tttctttgtc tgtgcttcga tcccttttgc actatcgatt accatgaccg cactatccac
    39001 ggccatcaaa gtacgataag tatcttcaga aaaatcttca tgtcctggtg tatccaagat
    39061 atttactcgt ttcccttgat aatcaaactg cataacagaa ctagtaacag aaatcccacg
    39121 ttgtttctcg atttccatcc agtctgattt ggcaaaatta cctgtttttt tgccttttac
    39181 ggtcccggct tgacggatag ccccaccaaa caatagtaat tgttctgtaa tcgttgtttt
    39241 cccagcatcc ggatgggaaa tgatcgcaaa agttctgcga ttgtccactt gttgctttaa
    39301 ttttggatta ttcataacct aactccattt cttccattca attatttata ttttctctag
    39361 gcacagattg tccgatctct taaagaaaga caatttcata tagggctgtg acaaaagccg
    39421 tgtagcagtc tctttttccg agtaaacggc gttctagaga cagcctatca gcaataagcc
    39481 cacccaagcc aaaaatacga aaagctgttt ttgcttggct gctcttatta cttaatgcag
    39541 gatagctttt tcacaacctt tgtcaactac tacaactgaa tcagtatagc atggattcag
    39601 cgaatgaaaa agccaccaaa ccataagagt caaatatttt tttgtcagct gactaaaaga
    39661 aaagacgtgt tgcttgttta ttcaagcaac acgtctttca taaccaagtt tccaattatc
    39721 ttcttggctc gtcatcttcg aattcttttc tgaagtatct tcgttcttct tcaggttccg
    39781 cttctgtttc ttccggatca tgaaaaatga cacggatttt aaggattcga gaaccttcca
    39841 tttcttcaga aaccagcgta atattatcga catcaaacga taacttttcg ccttcatccg
    39901 gaatcatgcc taatgctgta atcaaataac cagccatcgt atctacatca ctcatatgca
    39961 gatcactgtc aaaagcttca ttgaactcat caatcagcat acgtccttgg atgatatatt
    40021 cgtgttcatc gattttttca taaagattct caacttcatc tgattcatca tcgatttctc
    40081 cgacgatttc ttctaaaagg tcttctagtg ttgctaaccc aacgacgccg ccatattcat
    40141 ctaataaaat agccatctga ttctgcgtct ttttcatttc atataacaga tcatcaataa
    40201 agaccgtttc aggaacgaat aaaggctcct gcatgatttt cttgatatct aaattatcaa
    40261 agccgaattt atgggcagct tttagtaaat tctttgtatg aaggattccg actactttat
    40321 ctttgtcttc gttataaaca gggattcttg aatagttttc ggataaaact tcattcacat
    40381 tttcttccac agtgtcgttg atatcaatca taaatgcatc cgttcgtggg accatgactt
    40441 ctcgggcaac tttcgtatca agagaaaaaa ccccttggag catttctaat tcttcattat
    40501 tcaatacgcc ttcgttttca agcatataac gcatttcatc tctggtcatt tttgaatctt
    40561 catcatcaaa agtcatcggc gtgatacgcg ccaataaact tgtggaagca gaaagcagcc
    40621 agacgaaggg cttagctact acaccaatca agcgtatcag ccctgaagtg aactttgcga
    40681 cttcttctga tttatttaaa gcaatacgtt tagggtacaa ttctccaaaa acaatcgata
    40741 cataggtcaa aatagccagc acaatgatat ttgcaatatt ttttgccgct gtgccgccac
    40801 ctaataccgg agctaaccgt tccgataaag tattagctag tgaagcacca gacaaaatgt
    40861 tgaccaaagt gattcctact tggattgtcg ataggaaatt atttggattc tgcaatattt
    40921 ttaaaagctt ttgagatttc acatctcctt catcagcttt ttgctcgatt cgattcttat
    40981 tgatcgaaac aacagcaatt tcggaagctg ctaaaaaagc attgatcaat gtcaaaacga
    41041 tcaataataa aatctgcgct aacagcgact gactctcagg gtcagcattc ataatcgcat
    41101 tctctcctta taaaattaat ttttagttta cgatagaaaa aaacgtggca ctatagccac
    41161 gttaaaatgg tatcacaaag caattttctt tgcaataaaa acaagtgtac taaaactacc
    41221 tacgaggtcg tagcaatttt cttcttgttt tcattttgct tgtcttcttt gacgattttg
    41281 attatatagg aaatgatcgt cttgcagatt gcgtaaaaag gaacacctaa gaagatacca
    41341 agcaatccgg caatatttcc agctactaga agaacgataa tgatcgttaa tggatggatt
    41401 ttcagtgatt tcccaattac attaggataa atgatattcc catccaactg ttggacgatt
    41461 agcacaacca cacaacaaag taatgctttt accggatcat tgaagactgt tactagaaat
    41521 gcaggtgcta gtcctagata aggtcctaaa tatggaatta ggtttgtcaa tcccgcaatg
    41581 accccaaata agaaagcata atccacacca attaccatat atcctaaaaa tgtgaaggta
    41641 ccaacgaata aacattcgat tgcttgtccg ctaatgtaat tagccaatgt tttattcagt
    41701 tgccccaata actccacaat ttggtttctt cttttttctg ggaaaaactg ttggatgttt
    41761 ggcactagtt tttctccgtc tttcaacata tagaacaaga tgaatggtgc tgtaatgatt
    41821 actacggttg ccgaagcgat cgttccaacg atcgaaccta aactattgga tactccacta
    41881 aggaattgct gaatgattgt cccgtaagaa atgtctaatt gctcaaaata tttattgata
    41941 tctacttcct tgaacaaagg caattcggct acctctttta accagctttc tacctgtttg
    42001 atgaaatcag gcatattaga tgccaatgag gaaatttgct gtactagact tgggatgaca
    42061 ctaagtaaaa tccaaataat tgctgcaact aaaaggagca gcacaattgc gacagcccat
    42121 attcttttga tttttgcttt catcaacagc ttgacaatag gattcaataa atagtaaaga
    42181 aagcctgcaa tcagtacagg tgcaaataac gtggaaaaaa atgtcccgat cggttcgaaa
    42241 ataaagttta tttctgatga aatcatgatc aatgcagcta tgatcaataa ttcaagcgac
    42301 caaaacatta gtttagactg tctaagtttt tcaaacaata gatttcctcc tttctttctt
    42361 actagtatat attatattcg ttaaaaattc ttttattctt tttttatttt tgaaaacttg
    42421 ccatactttt tatttgtttt attttccagt atactatacg aaaggaaggt ggctagacca
    42481 tgaaagttgt acaaacaaaa gatacaatga gcaatattta cttagatgct gtacggatca
    42541 ggcatcaagt ttttgtagtc gaacagggtg tgcctttgtc tcgagaaata gacaaagatg
    42601 aagcccattg tatccacttc gtcctgtact cagataaaaa agaaccgcaa ggaactgtac
    42661 gtcttttgcc tttagaaaac ggaaaaatga aattacagcg gatggcgatt ctttctgaat
    42721 acagacacca agggttagga aaaatattga ttgaagaagc agaaaacttt gctaagaatc
    42781 aaggctataa tacgatttta ttaggggcac agtccacagc tgaaactttt tacgaaaaac
    42841 taggatatac agcttacggc gatccttttg aagatgctgg catgcctcat atttatatga
    42901 aaaagacttt ataaaaattt atttcgaaaa aagcaaaaaa cagcaagctt ttgagaaaaa
    42961 tctctcactg gcttactgtt cttttttgtg tttacttacg cgacaattgc ttgtaacggt
    43021 tataccaaat atcaatatag ccttccgaga acgggccatc tccattattg atccagtcaa
    43081 ccagaatctt cacattttct tttaggatga agtcaatatc gttcgggtaa ttcatcattt
    43141 tgctgtgcat ctcatattca tcgacatcca atagtcgttt ctcgccgtca ggaaatacct
    43201 tgatatccaa gtcatagtcg atatatttca aggcctcatc gtccagcaaa aaaggtgaag
    43261 ctagattaca ataataggaa accccctttt ctctgatcat tgctattaca ttgaaccagt
    43321 attttttatg aaaataaaca atcgctggtt cgcgcgttac ccatcggcgt ccatcagatt
    43381 cagtgactaa tgtgtgatca ttcacgccga tcatagagtg ttcgcttgtt tttaatacca
    43441 tggtatctcg ccacgttcga tgcaatttgc cgtcgtgctt gtaactttgg atcgtcacaa
    43501 actctccttc ttttggaact cccatagcaa cccttcctta agcagcattt tgtgctttgt
    43561 gtttgggtgt tcattacacc gacatcataa ttattatatc aataaaaatg agctttgcct
    43621 agaaaggatt cctattgttt cgatttttct ctaactgatc taccagtttc atttggacct
    43681 taggaaaaac gaccgaatca aatgcatcag gcttcaacca cttcgaagtt ttgttctcgg
    43741 taaattcttg ttctgctccc tcggttgccc gtccgtaaaa aaggagaaca tgccatttca
    43801 gatgactaaa aatatgagta acttctccta aatgtcgtgt ctgccaaaca aagagttcct
    43861 gcttttcaaa tgggagattt tgctcttctt ctgctactag gtcatcaaac agatcgattt
    43921 ctggctttgt ttcccattct tttttcaatc gctcatactc ctcttgtgtc acttccatca
    43981 ttggaaatgt ccacatattc gccagcaatt tttggctatc tctttcttca aaataatacg
    44041 ctccagaatg attttgaaga gctgcactga tataataaac gtcttttggc tttgcttttt
    44101 ttgtttttac aggaaaactc gtttggattc ctcgtttgtt agctaaacaa aaggcttgga
    44161 tcggacaagt ctcacacttt ggagaagttg gtgtacagat agctgaacct agatccatca
    44221 ttgcttggtt gaattcacct ggatgctttt catcaatgat tttccgcatc gcttcatcaa
    44281 agattttcct gctagaagct tttgcgatgt ctgcttcaat gcaaaacaat ctgctgacta
    44341 ctcgcatcac gttgccgtca actgcaggtt ctggaagtcc aaatgcgata cttgcaatcg
    44401 cgcctgtcgt atatggtcct attcccttca atgagctaat ttcttcaggc gtttgcggca
    44461 tttccccatc aaattctgac atgatctgtt tagcagcagc ttggatgttc cgggctcttg
    44521 agtaataacc aaggccctcc catgctttta aaagcttttc ttctggagca tttgctagct
    44581 cttcaattgt aggaaaccat tccatgaaac gataaaaata atcgatcact gtgtctactc
    44641 tggtttgctg aagcatgatc tcagagatcc agatacgata aggatcacga ttatagcgcc
    44701 aaggcaggtt tcttttttct tgttcatacc attgaatgaa ctgatcttga aattcttttg
    44761 tttctttatc tgtccatttt tcccattctt tattcacttt cctcttcctt ttccgtaatg
    44821 aatcgctgga tcatatccaa atcaaatcct ttttgatata agctttgctt tacttttaga
    44881 tttctttttt taggttcaaa ccttaaattt cttcgccata gtttatctcc ttgtttgact
    44941 aaataatcat attctatttc ttgatctgct tcttgcggaa gatcagctat cgcttgttgg
    45001 atcacttctt gagaaaagcc tttcgtcatc aatgtttgtt ggatttttct caataattct
    45061 ttttggcttt ttccgtgatt ttttccaaac gctttttcgg ctgtctgatg tgcattttga
    45121 acttggtctt caaatgtata ttggctgagc gcttgttcaa tgatttcagg tttcaaacct
    45181 ttttgctgca tctgctgcgc taatttcttt ggtcctttgt cacttaagcg catattcgtg
    45241 cgcacataac tttccccata gaccaaatca tcgacaaggt ccaattcttt taagcgggct
    45301 acgattttat ttcgatcttc ttgaaggatt tccttttctt ttaagtatgt tcggatttct
    45361 ttttccgatc gcaactgata acttaagtaa ttcattgcta ggtgaaaacc gaaatcagct
    45421 ccgctactct tcttgatctc ttggatagtt tcttcgtcta attcccgtcc ttttaataat
    45481 cgatagcgta ctaatacatc ttcagatact tgtaaagctt ctccttcaga taaatctacg
    45541 cgatagaaag ggcctttgcc tttactgatt ctcgtaacgg ttaacataaa catcctcctc
    45601 gaacatatat tctctatcat accacagaaa atccccgtaa tcaggtatta tatgttagaa
    45661 taaaccacag aaaaaagaaa aagggagata cttatggcag aaacaattgt caaaactgga
    45721 caaacggttc ctttgaaaat caagcgttta ggcataaatg gtgaaggaat cggttatttc
    45781 aaacggttga tcatatttgt tccatatgca ctaccaaaag aagaagtact agtgaaaatc
    45841 acgaaagcaa ctcctcgcta tgcagaagga gaattaataa aagtcaaaaa aacaagcaaa
    45901 gatcgcgtag tggcaccatg tcctgtttac tatgaatgcg gtggctgtca attacaacac
    45961 ttagcttatc aagctcaatt ggattttaaa aaggatctgc ttttgcaagc attggaaaaa
    46021 ttcaaaccag caggctttcg atcttatcaa cttttgccga cgatcgggat ggatgagcct
    46081 tggcattata gaaacaaagc acaatttcag ttacgaaaaa ataagcagac tcaaaaaatt
    46141 gaagctggtt tatacgaagc aaactctcat cagttagtcc ctataacaga ctgcttggtt
    46201 caagaacctc gaacacaaaa agtaatgaat actgttgttc aactattgaa taaatttgat
    46261 gcacccatct atgatgaacg gacaaacagt ggaatcttcc gcacaatcat ggttagaatc
    46321 ggtgttaaaa ctggggagtt acaagttgtt tttattactc gcagtaaaaa attcccgcaa
    46381 aaaaacgcaa tgatccgtga gatcaatgaa cgactgcccg aagttgtttc aatcatgcaa
    46441 aatgtccagg cacaaaaaac gtctctcgtg atgggggatg aaacgatcca cttatgggga
    46501 aaagaagcca ttgaagaaca aatcaatgaa gtgactttcg atctttctcc tcgtgccttc
    46561 tttcaactca atcctcagca gaccgaattg ctttatggcg aaggaatcaa agcattagat
    46621 gtccagccta atgaaacgat cgtggatgct tattgcggag ttgggacgat cggcttaagt
    46681 gtagcaaaac aagccaaaga agtacgggga atggataccg ttcctcaagc aatcgctgat
    46741 gcaaaaaaaa atgcggaaag attaggatat cacaacactc gatatgaagt cgggacagca
    46801 gagcaagttc tgcctaaatg gttgaatgaa ggttttcagc ctgatggtat catcgtagat
    46861 ccaccacgta cgggtttgga taacgcattg atccaatcat tattgaaata ccctccaaaa
    46921 aaacttgttt atatctcctg taatgtttct acacttgcca gagatctggt taatttaagt
    46981 aaaaagttca agattgaata tttacagtcc gtcgacatgt ttcctcagac tgcacgttgt
    47041 gaagttgtcg tgaagatgac gagactcgct gactaaatga aagaggttgt gaaaaagtct
    47101 gccctgtatc aagtaataag aacagccaaa caaaaatagc tcttcatgtt ttatgaatac
    47161 tgtacttgtg accgaagagt taacaggagg acactattta tttaaaaaaa gggttgtgac
    47221 atagtttttg tcacagccct ttttgattat tattggatat tcacgtctat cacttgataa
    47281 aatgcatttg tcgtatcgct gatattccat actgctaaaa tcacattata tccttttcga
    47341 tcctgcggaa gtgtgatcgt ttggttgact gtttttggtg gaacagttgc tttgtcgtct
    47401 atttttgtga tcaattcaaa atcactaaat ttcaaaggtt gattaggatt ccaagttggt
    47461 ttggtaatgt agtaatccca agtacttgtc cgatgttgtg ctgttaaatt ccaagtaata
    47521 tttaatgttc ctggattaac catgttttta tgccatctgt tagatgtctg ttcatctaaa
    47581 ggctcaaagc cgctgactcc tgcactagca atttttccat caatgaatgt atttttggta
    47641 gcttcgatac tttgcggttc ccattgtgct cttccgacat tttgatttaa gtttcctgct
    47701 gctgatgttc ctaggtatgc acggcttcct ggagaagtaa tataaccatg cgcaaaacct
    47761 ggaatgctaa aaccgaacaa ccctaaacta actaacccaa taaacaataa cgtactaatc
    47821 tttttcatgt agaaacctcc ttcatttgat aaccacattg taaacgcttt attgtattaa
    47881 cacaaacatt atgcttttat aattttatgt tgaagtaaaa aaggtgaaaa aagtaagatg
    47941 cagattataa cagaagtaga cgagaaaagt acaaatagaa aacatgagaa tcaaatcata
    48001 tgatcttttt caaaaacatc attcatataa acaaatgttc aactttttaa taacaacaat
    48061 tatcaatttt tttcttactt cacaaactaa atacaggtct tgctgtgagc cttcatggta
    48121 aactaatatt atagaaagga gttagtaaaa tgaagatgat aaaagatatt cgtttttggg
    48181 tttgtgttat aggaattgtc atattaggct ttttatcagg gttgcttagc ggaaatcccg
    48241 gaaaatatta ctattctttg caacttccac catttgcacc acctagctgg atatttgggc
    48301 cgatgtggac cttactgtat atattgatgg gtatttctct ttatttgtta cttaatcaca
    48361 acaacaaaaa acagcgaaac aatcttgtcg gtctttttgt gattcagttc atttttaatt
    48421 ttatatggtc tgctctattt tttaatttaa gaaatatttt cattgcagca atcgatatta
    48481 cacttttagt tattttcttg tcagtgctta tgtatcagtt gtggctgcat catcgcctgg
    48541 caatgtggct catgattcct tattatttat gggtactatt cgcaactcta ttgaattatt
    48601 caatttattt tttaaactaa gcgctaaaaa gagacgtcct gtaatttaac acatagaaaa
    48661 agtgccacct aagttagatt ttttgtctaa tttaggtggc actctttatt aaccaaacta
    48721 tttttttcta gtacccactt gttgttccat actcattatt ctggtcataa ccataaccat
    48781 tttgttcctg tccagcgtaa ggatcataac tttgagtatc ttgacttggt gtatagtact
    48841 gacttgtatc ttctgtttgc tgataatagg tattcggatc ttggtactga tcatatgtgt
    48901 tttctgaata ggaagaataa tcggtgtacc cttcactatt cgatccatca ccgtttgtcg
    48961 aatcgccatc ttccgaatca tcaaagaaca tcattgaagc attctcattt ttcaaattag
    49021 gtaatgtatc gcttgttttt atatttaatt gtttcttcag ttcattttgg atcgaaagaa
    49081 gatcattttt tcctaaaatt tgatagtaga tatcattgat catttgtcct tcgccttgca
    49141 actggtcttg tttgattgtt tcaaacgccg gggtgtagtt cgtcgctaca tcaagcatgt
    49201 catcccaatc taagtccgtc gtcacattgt tctcaactgc ttttaaaatt tttctataat
    49261 tgcttacgcc atctaaactt aaaactttat tgacgatttt cgtcactact tcccgctgac
    49321 gacgttgtcg accgatatcg ccttctggat cttcgtgtcg cattcgagaa taggctaaac
    49381 ctttttctcc attcaatgtt tgttcaccta ctggtacatg gacaccatcc aaagtaaagt
    49441 caattttatt attcactttg atgccaccga ccgcattgat caaatcttcc atgccatcca
    49501 aattgatcgt tacataatga tcaataggaa tatcgagcag ttgctcaatt gaatccatgg
    49561 ccatttcgac accaccaaat gcgtaggcat gatttaattt atctaccgtt ccataaccta
    49621 cgatattcgt ataaatatct cggtccaaac tgatgatcgt tgattttttt tgtttcggat
    49681 taactgttac taccatcatc gtatcagaac gtccttgttc cgttcttcct aatccaccgg
    49741 tatctaaacc taatagcaaa accgaaaaag gttctttgtc atcaatgctt actctctcag
    49801 aacgtttgga ggatattcga ttagagtttt tagaaatttt gtttactgtt tggctcgctt
    49861 ctcccataaa tctgattccg tatgctgata atccggcaat cagcaaaacg aataccccta
    49921 acaaggttaa tagaactttt tgccatcgct tcataataca cctctgtttc acattttcta
    49981 aaatattgtc tcatataact gttcaatcag caaattcact ttttaatcat aagaaaactt
    50041 taaaaaacat ttttgtgtaa cgattattat tttttaaaat ttctcaaaat tcttaactat
    50101 cataccatac cgtgaaaaag atcgaaagac cgaatacacg cagttcgcaa tcgttttatc
    50161 tttttttatg tattttttcc agaaaaagcg aacaacaagg tattttccaa ataatcgtgc
    50221 agtaaaatga tcgcacatac ctttcccatc tttttaacag tctttgccta ccgttcagat
    50281 tatcattcga tttcacgaca atttcttcct atgactggtc cttttgttaa acccatcttc
    50341 tattcgtttt atttccagct cactgcatgg ctcttaaaat gactcgaact agtgattgca
    50401 ttaccatcat cttttaatgg atagatatgc tcctcttcaa agtaaaacga ttttctttta
    50461 aagtaataga attgacatgg taatgagtat gtatactagt ggtttcacaa atggtctttt
    50521 attcaacatc caaaaactga aatttcttta aaatccatta ctaacgaaga aaatgttcct
    50581 tgcttgataa ttagttagga catgtcaagt gaacaaatgc atttacttag ccaaaaaatc
    50641 taaaaacttc ataaatagac aaaaagacac gactctctaa gaagtcgtgt ctttattcaa
    50701 caaattatta taatttagtc acttcagcag cttgaggtcc gcgtgcacct tcaacaatcg
    50761 tgaattctac ttcttgacct tcttctaggc tcttgaagcc gtctccttga attgctgaga
    50821 aatgaacaaa tacgtcatct ccgccgtcta ctgtaataaa cccaaatcct ttttcattgt
    50881 tgaaccattt aaccgttccg tgttccataa atgtatatcc tccaaaaaag ttcttgcaag
    50941 taaccttgca agaacattat acccaattta gaaaacgcta gcaagctttc gctcttttat
    51001 tttccaaatt atttttaaga ctgatatgac ggaggaaatg gttattttgc tgcttcgaaa
    51061 cgtttgttta cttcatccca attaataaca ttccagaatg ctgcaatata atctggtcgg
    51121 acatttttat atttcaaata ataagcatgt tcccaaacgt ccaaacctag aattggtgtc
    51181 tttccttcca tcaatggaga atcttgattt gcagtagagg taatagctaa ttttccattt
    51241 tccattacaa gccaagccca tccagaacca aatcgtccag cggctgcttt tttgaattct
    51301 tctttaaaag aagaaaaatc accaaaagct tcattaatcg cttcttttat ttctcctgta
    51361 ggttcgccac cagcatttgg tgccatgatt tcccagaaaa atgaatggtt agcatgtccg
    51421 ccaccattgt tacgtacagc tgtcttgata tctgttggaa tagcgtccat atcagataat
    51481 aattcttcta ttgttttttc gcctaattct gggtatttct caattgctga atttaaattc
    51541 gtcacataag tattgtgatg cttatcatga tgcagatgca tcgtttcttc gtcaatataa
    51601 ggttccaatg cgtcatatgc ataaggtaga tctggtaatg tgtaagtcat aaaaaaattc
    51661 ctcctcaatg ttttcttaat aatgtctaca ttacaaagag taacaaagag aaggaaattc
    51721 ttcaattgtt atgcctagtc gtctttttca ctttgaccta cttcttcttc aaaaacctca
    51781 gtttctttaa aaataaacaa cttgctgaaa atatagttcg caaggataac aataatttga
    51841 gtgatgattt tcgccacata ctcattgctg ttcataacat tgatcaacaa taccattgcc
    51901 cccatgtcca atccgtaaga aaggatacgg tagaagaaga acttaccgca ttcaataagt
    51961 gcatgtgtaa aattcggtga ttttgaatgg aatacccaaa gtttgttcgt tacaaaagca
    52021 aacaatacag aacaaaacca cgaaatagaa ttggataagg ccatacttaa atcaaaatat
    52081 tggcgtgcga gagcaaaact aacaaaattt acaatcgtag ccaaaccacc aaaaaagaga
    52141 tagactagta tctcccaata tccttttgct tctaaatatc cttttaactg tcgatactgc
    52201 ttcatgagcc aacctacctt attaaaaatt cttatttatc atactctata tttcaataac
    52261 tttcatcttt atttaaaaaa attaattttt tttgatcctt tgcctttgtc tctgcttgga
    52321 tcgtcacatg tgtaatacca tattttaatt ttaataaaga aattatacga ggatatatct
    52381 tttcaatctc gcttagtagc tgatcttcaa aatcaatatg tccgtcgaaa ataattatct
    52441 tttcgctata ctgccaaata tggacatgat gaacatcctt taccccatcg attgcttcaa
    52501 tttcttgttc cattttttca tagtcgatag caggtgcact ttgtatcaaa atagcggcag
    52561 cttttttgat caccattatc gcttctatca atatatatat cgaaatgatc agtgtaataa
    52621 ctggatcgat ccagtagata tcgaaaaaac ggatcaaaat tgctccgata atcacactta
    52681 ccgaagacag tgtatcactt aacaaatgca aataactaga ttttatattc aaactttcat
    52741 ctgcttcttg tcgtaataat aatactgaga acaaattcgc gagcaatcca ataactgcta
    52801 ctgttagcat caaatgacta tttatctttt ctggtgaagt gaaccgcttg aatgcttcaa
    52861 cggttaaaaa caaggataat atgatcaata tgaatgagtt gatgaaagca ctcaatattt
    52921 ctaaacgctg gtagccatac gtacgttttt tatttgcttc ttttcgggcc attttttgtg
    52981 ccccgtaaga aaaaataatt gccaatgtat cactaaggtt atggaaagca tctgaaacaa
    53041 gagacaaact ccctgacata atccctccaa taaattctga taaagtgatc accgcattca
    53101 aaaccactac tccaaatagt ttttttgatg atctctgtgg ctgtgtaggc actattcctt
    53161 cctccatttt atttatattg gatagtcttt agacaagaat aacatttttt tgatatttca
    53221 ccaatcattc agctgtttcc ttaaagcact tgtatttcac ttgatacttc gctagaattg
    53281 caagtgatga cactactaga tgaggagtac ttatgacaac aaaacaatta attatcagtt
    53341 cctttatacg attcaaagac ctaaaggagg cgagaaatgt cccattttgg aaagccattg
    53401 tctatctttt agttttgagt ataattatgg ctttgccaat ctcttttcaa gtttttcaag
    53461 tcttaaacaa cattcaattg gatgggcaaa agattgctac tcgcattcct gattttacaa
    53521 tccaaaacgg gcagcttcaa accgaagaaa aagaaggatt catttaccaa acaaactcca
    53581 ttatcttcac atttgatcca gagggaaaac gaacagaaca ggacatctct actgatttga
    53641 tggggaattt tgttagtgtc gggatgttaa aaaacaaact tatcatagct cttcctaata
    53701 caggcacgac ttctgctttg ttgaacaata accaattaga acttccctac accaatgaat
    53761 ctttaaaaaa cttaacaggt aagcagctcc gttctttttt aagtgaagca tctataccac
    53821 tttggataaa agtcctgaca tttatatttt ctatttatcc tagttttctg aatctgctga
    53881 tcactttgct atttaccaac attgctgctt ttctctatgc acgctttcga ctaacaaaag
    53941 ctacttttct tgattgttta aaaacattga tctattcaat ttcattgcct actataattg
    54001 caacaatctt gatggtcttt cttccttctt ttgacactag cgccttcatt gcttttgcag
    54061 gaatctttat ttttgctcaa gctgtcaaag gatgggcaaa aatatcgatc aattaagaaa
    54121 taaagacaac tcgttatttc tacttcaata gaccctttta gaggttgtga catttttttg
    54181 tcacagcccc ttttttattt gaaaaatatt tctttctcaa aaaacaagca aggcgcttca
    54241 aagttcttct tgtatgcgct acacttagag taaagaaagg cgggaaatta actatgtcag
    54301 aaagaatcat ttatgcagat cgtccatttc gtgatgaatt tatcgaagaa atccatacta
    54361 tagcgcctgg ttatatcttt aaaacagaat tacaaccaga ggatctacaa aatgtagaga
    54421 tcagtttggg ctggaactca gactaccaag aaaaactatt agcctcttct accttgaaat
    54481 gggtccaatc tatctcagct ggtgttgatc agctacccct tgagactttt tcaaagaaac
    54541 atattttact ttcaaatggt agtggcatcc acagtgaatc gattacggag catgtcttag
    54601 gaatcatcct tgggtattct cgtggtcttt ttcaagcaca aaaggcacag agtgacatga
    54661 aatggttagg ttcatcggtc cattaccaat ctatccaagg gaaaaaaata ctaatcattg
    54721 gaactggcca tattggaaaa atgattgcaa aaaaatgcaa agcattagac atgaactgct
    54781 atggaatcaa tacatccggt catccagcag aaggaatgga aaagactttt tctttaaatc
    54841 aactaaagga agttcttcct gaagtagatt tcgtagtcaa tatcttacct ctaacggagg
    54901 aaacaactgg gctctttgat cagcatatgt ttgaacactt tgatccaaaa tctgtattca
    54961 tcaatgttgg ccgtggtgct tctgttaaga cacaagatct ggtgcaggct ttaaataacc
    55021 agcaactttc ctttgcagca ttagacgttt ttgaggaaga gcctcttcca caagatcatc
    55081 ctctttggaa aatggacaat gtactgatta cttcccacat tgcaggtttg acacctgatt
    55141 ttcaaaagaa attaatggct atttttttaa ccaatctgaa aagctacttt gccacccatg
    55201 agcttcaaac caatcaagta aa
//
LOCUS       DAFENC010000017        49996 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.017, whole genome shotgun sequence.
ACCESSION   DAFENC010000017
VERSION     DAFENC010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 49996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49996
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.017"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..1008)
                     /locus_tag="LP493_001292"
     CDS             complement(<1..1008)
                     /locus_tag="LP493_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL2133452.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(1188..1532)
                     /locus_tag="LP493_001293"
     CDS             complement(1188..1532)
                     /locus_tag="LP493_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBL2133453.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(1525..1959)
                     /locus_tag="LP493_001294"
     CDS             complement(1525..1959)
                     /locus_tag="LP493_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HBL2133454.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            2097..2834
                     /locus_tag="LP493_001295"
     CDS             2097..2834
                     /locus_tag="LP493_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2133455.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            2827..4038
                     /locus_tag="LP493_001296"
     CDS             2827..4038
                     /locus_tag="LP493_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2133456.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            4242..5024
                     /locus_tag="LP493_001297"
     CDS             4242..5024
                     /locus_tag="LP493_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HBL2133457.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            5094..5756
                     /gene="trmB"
                     /locus_tag="LP493_001298"
     CDS             5094..5756
                     /gene="trmB"
                     /locus_tag="LP493_001298"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HBL2133458.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(5854..7608)
                     /gene="ade"
                     /locus_tag="LP493_001299"
     CDS             complement(5854..7608)
                     /gene="ade"
                     /locus_tag="LP493_001299"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBL2133459.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNNQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            7740..8669
                     /gene="tadA"
                     /locus_tag="LP493_001300"
     CDS             7740..8669
                     /gene="tadA"
                     /locus_tag="LP493_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HBL2133460.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            8626..9675
                     /locus_tag="LP493_001301"
     CDS             8626..9675
                     /locus_tag="LP493_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HBL2133461.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            9672..9950
                     /locus_tag="LP493_001302"
     CDS             9672..9950
                     /locus_tag="LP493_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBL2133462.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            9925..10395
                     /locus_tag="LP493_001303"
     CDS             9925..10395
                     /locus_tag="LP493_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HBL2133463.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            10412..10714
                     /locus_tag="LP493_001304"
     CDS             10412..10714
                     /locus_tag="LP493_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133464.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            10731..11102
                     /locus_tag="LP493_001305"
     CDS             10731..11102
                     /locus_tag="LP493_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HBL2133465.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            11074..11433
                     /locus_tag="LP493_001306"
     CDS             11074..11433
                     /locus_tag="LP493_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133466.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            11605..12612
                     /locus_tag="LP493_001307"
     CDS             11605..12612
                     /locus_tag="LP493_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL2133467.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            12637..13821
                     /locus_tag="LP493_001308"
     CDS             12637..13821
                     /locus_tag="LP493_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HBL2133468.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(14258..15841)
                     /locus_tag="LP493_001309"
     CDS             complement(14258..15841)
                     /locus_tag="LP493_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBL2133469.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(16419..16562)
                     /locus_tag="LP493_001310"
     CDS             complement(16419..16562)
                     /locus_tag="LP493_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HBL2133470.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(16785..17264)
                     /locus_tag="LP493_001311"
     CDS             complement(16785..17264)
                     /locus_tag="LP493_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBL2133471.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(17337..17621)
                     /locus_tag="LP493_001312"
     CDS             complement(17337..17621)
                     /locus_tag="LP493_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133472.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(17699..17893)
                     /gene="ssrS"
                     /locus_tag="LP493_001313"
     ncRNA           complement(17699..17893)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="LP493_001313"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(17965..19251)
                     /locus_tag="LP493_001314"
     CDS             complement(17965..19251)
                     /locus_tag="LP493_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HBL2133473.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            19389..20060
                     /locus_tag="LP493_001315"
     CDS             19389..20060
                     /locus_tag="LP493_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HBL2133474.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            20026..20514
                     /locus_tag="LP493_001316"
     CDS             20026..20514
                     /locus_tag="LP493_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HBL2133475.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            20527..21474
                     /gene="prmA"
                     /locus_tag="LP493_001317"
     CDS             20527..21474
                     /gene="prmA"
                     /locus_tag="LP493_001317"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HBL2133476.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            21475..22239
                     /locus_tag="LP493_001318"
     CDS             21475..22239
                     /locus_tag="LP493_001318"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HBL2133477.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            22472..24685
                     /locus_tag="LP493_001319"
     CDS             22472..24685
                     /locus_tag="LP493_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HBL2133478.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            24696..25142
                     /locus_tag="LP493_001320"
     CDS             24696..25142
                     /locus_tag="LP493_001320"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HBL2133479.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            25313..26572
                     /locus_tag="LP493_001321"
     CDS             25313..26572
                     /locus_tag="LP493_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HBL2133480.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(26661..27608)
                     /locus_tag="LP493_001322"
     CDS             complement(26661..27608)
                     /locus_tag="LP493_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBL2133481.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            28002..29294
                     /locus_tag="LP493_001323"
     CDS             28002..29294
                     /locus_tag="LP493_001323"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HBL2133482.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            29309..31078
                     /gene="aspS"
                     /locus_tag="LP493_001324"
     CDS             29309..31078
                     /gene="aspS"
                     /locus_tag="LP493_001324"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HBL2133483.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            31187..32062
                     /locus_tag="LP493_001325"
     CDS             31187..32062
                     /locus_tag="LP493_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL2133484.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            32328..34211
                     /locus_tag="LP493_001326"
     CDS             32328..34211
                     /locus_tag="LP493_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBL2133485.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(34286..34570)
                     /locus_tag="LP493_001327"
     CDS             complement(34286..34570)
                     /locus_tag="LP493_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBL2133486.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(34560..35294)
                     /locus_tag="LP493_001328"
     CDS             complement(34560..35294)
                     /locus_tag="LP493_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HBL2133487.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            35423..36046
                     /locus_tag="LP493_001329"
     CDS             35423..36046
                     /locus_tag="LP493_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBL2133488.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            36238..37359
                     /locus_tag="LP493_001330"
     CDS             36238..37359
                     /locus_tag="LP493_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HBL2133489.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            37366..40494
                     /locus_tag="LP493_001331"
     CDS             37366..40494
                     /locus_tag="LP493_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HBL2133490.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            40513..43707
                     /locus_tag="LP493_001332"
     CDS             40513..43707
                     /locus_tag="LP493_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HBL2133491.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(43853..44560)
                     /locus_tag="LP493_001333"
     CDS             complement(43853..44560)
                     /locus_tag="LP493_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBL2133492.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            45325..45723
                     /gene="spxA"
                     /locus_tag="LP493_001334"
     CDS             45325..45723
                     /gene="spxA"
                     /locus_tag="LP493_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBL2133493.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
     gene            46055..46708
                     /locus_tag="LP493_001335"
     CDS             46055..46708
                     /locus_tag="LP493_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HBL2133494.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            46934..47932
                     /locus_tag="LP493_001336"
     CDS             46934..47932
                     /locus_tag="LP493_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HBL2133495.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            48108..49916
                     /gene="pepF"
                     /locus_tag="LP493_001337"
     CDS             48108..49916
                     /gene="pepF"
                     /locus_tag="LP493_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBL2133496.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
BASE COUNT        16175 a         8741 c        10455 g        14625 t
ORIGIN      
        1 ttttgatgaa tcagttgttt cttcagttga agattctttt gttgaatcag ttgattttgt
       61 gtcagaactc tttgttgaag ctgtagtttc acttgagtct ttcgtacttg atgaagttgt
      121 tgtgaatgca ctcaacacat tttcaaaggc atcatctttg atttttacat ttgcatcttt
      181 taattcttca ccgattactt tagttgtgaa tgcattgtca cttagtttag tttcagtagc
      241 gatatctttt agttgatctt tgtatttatc catgtcattg cctttatttt ggtttttcac
      301 cattttgaca acgtagtatt ctgtcgcata agaagtagga tttgttgtag taataacatc
      361 ggagatctca ccgtctttca atttgaaagc tgcttctttt acttctgcag gaatagttgt
      421 tgtcgttgag tcgaatttaa ctttaccgcc atcttctttt gtctctgtat cagttgattt
      481 gtctttggct aatttagaga aatcatctcc atcatccgct gattttttca catcttttgc
      541 ttcatcttca cttgataatt tgatgatttg tgcttctact tctggatgga aagatttcca
      601 agcagttttc aaatcgtcat ctgtaatatc tacgtgagct ttcaagccag cttcaaaagc
      661 taaattgtta cgaatatatt ctttataagt atctttcgta tatccagcag cttctaattg
      721 tgattcaaaa gtatcaccta atgatttcgc ttgtttgtcg tattctgcat ccacttgctt
      781 atcggttact ttatcgccat atttgttatt gaatacttta taaatgatca tccgttgtac
      841 taaggattgg ttcgatgatt caagttttgc ttcatcatag aaatcagata cagtgatcgt
      901 tccgcctttc atcgttgcga tatctttatt agtatcgcct gaacaagctg ctagagttaa
      961 aacagccaac gcactagtag ctgccaaaat aattgatttt tttttcatta aaatttgcac
     1021 tcctgtaatt agttattatt tttatatatt aactatacca tatcccattt cctttaaaaa
     1081 cgttgtcgtg gtagtttcaa acaaaattca aaatttcatc acattcctag gaaatacgca
     1141 aacttttctc acttatatag ttaaatctgt tgagaaaata atcattatta tatttgttca
     1201 ggatactctg gcagatcagc ttttagtttt tctacttgtt cattgatttg tgtgatacgt
     1261 ggttcggctt ggaatttaaa atcttcgata tcttttttga ttgcttcttg gaaagcagga
     1321 atcacagatt cagctgtttc ttttgtttcg atcaatgcgc ttttaaaatg attcaggctg
     1381 ttatttaaat catttgtcag agttgttgct tcttccaatt cttcgatcag tttctttctt
     1441 gtttcattcc cgctcctggg cgccaataac agacctccga cagtgccagc agcagctcca
     1501 aataacagtc ctttgaaaaa gtttttaatc atcgcaggac acctgcttta cgattgtttc
     1561 ttgaatagct tttagttctt ccgatccata actatcttga tgattgacaa agtgaataga
     1621 aaaatcatcc tctttgctgt agcgagggac taaatggata tgtgaatgaa aaacagattg
     1681 ataggctagt tcacggttgt tattcaagat attaagacct ttcatttctg gaaaagcttt
     1741 ttccaatgct tgagcaatct taggcacacg cgaaaaaacc tctcctgcaa gttcgggatc
     1801 atattcaaaa atatctgcta catgacgttt aggcacaact aatgtgtgtc ctttcgttgc
     1861 ttgagagatg tctaaaaaag catagacctt gtcgtcttca tatattttat agcttgggat
     1921 ttcttgattg atgattttgc aaaaaataca gttttccata taaaacatcc tttctataaa
     1981 gaataaatac ttcagcttaa ctttaccata agttaaagct attgtaagga aaaaaacaaa
     2041 ataccgtcat tttcttcgtg gtataataaa taaaaataaa tggcggagga aaaagaatga
     2101 gtttaattat cgatcatgtc acaggggggt acggacatct ccctgtgtta aaagatatca
     2161 gtttcgatgt acagcctgga gagatagtag ggttgattgg actgaacgga gcagggaaaa
     2221 gtacgaccat caagcacatt atcggtctgc tggaagcttc aaaaggaacg atagaaatca
     2281 atcatctatc cttaaagaaa aatacggaag aatatcgcaa acaaattggg tatattccag
     2341 agactccttc tttatatgaa gaattgacat tgagagaaca tatcgaagtc actgcgatgg
     2401 cctacgatat acctatggat atagcaatga aaagagcaga aaagttgttg gagacttttc
     2461 ggttatctaa tcgtcttgac tggttcccag ctaatttttc aaagggaatg aaacagaaag
     2521 tgatgatctt atgcgccttt ttgatcgagc cttctttata tatcatcgac gaaccatttt
     2581 taggcttgga tccactagct atcaatgcat tgcttgaatt gatggtagaa atgaaaaaag
     2641 aaggagccgg tattttgatg tctacgcata ttttagctac tgcagaaaaa tattgtgatc
     2701 gttttgtggt cttacataac ggagagatac gagcagacgg ttctcttgag atgttgagaa
     2761 aagaatttca gctgccggat tcttctttgg acgaaatcta tattgcttta acaaaggagc
     2821 aggcacatga gtagtttttt tcaaaaacgt ttagcaagac atcaaaagaa aatgatgaaa
     2881 tatatgcgtt atgtattgaa cgatcatttt gttttagttt gtcttttctt gattggcggt
     2941 gtgggattat attattctaa ttggttgaaa accctgcagc caccgtttgc aattggaggg
     3001 ctcataatct ctgtattttg gatgctctgt ttattcgtgg gtaagatggc tacttttgca
     3061 gaggcagcag atattgtttt tttacttcct aaagaaaaag aaatgcaaac ctatttggaa
     3121 cgagcttttc gctattcttg catttttccg ttgatctttt tgatattggc atgcggattg
     3181 gccatgccat tagtggtggt tagtacggag caatcctttt cgatgttttt cgtctatctg
     3241 atcatattat ggagtttgaa attcagtcat ctgcaaatca agagagcaga attgtttcga
     3301 ctagatcaac aagttattcg ttattggaaa ttaggctggt ttttttcttc tctgatcttt
     3361 ttgtttctat cattttattg gctaatatgg gcaggaatag caggtgcatt agtacaggca
     3421 agtctatatt actggttttt gtggaagcaa caagaaaaag gattggattg ggagaaaatg
     3481 gtgcatgtag aagaacatag gttgcatcag atctatcaat ttatcaattt attcacagat
     3541 gttcctgaaa ttacggcaaa gatcaaaaga agacgctatt tggatcctat attgactcat
     3601 attaaaagag aatcaaaaaa cacttatctt tacttgtttg caagaagatt ggcaagaggt
     3661 tctgatttta gtggtcttta tttccgatta gtaattatag gtgggttatt gattgccgga
     3721 gtagtcgact tttattttag tctgattatc ggtttcttat ttttatattt gatcggtttc
     3781 caactgttac ctttagcgaa ccagttccgc tatatggttc tcgttcagct ttatccaatc
     3841 cataagaatc agaagaagca ggcgattcag tatctactca catgggtatt aattatcgcg
     3901 tcggttattt ttggtttgat tgctgcagtc gtattagatg ggcagcagcg atgggttccg
     3961 ctagcggctt atttgattgt tactatgctc tttgttaaac tatatgtacc aactcgtttg
     4021 aagaagatgt cagactgaaa acaaagctgt gtagggtaaa aatgagaatg aaaaatagag
     4081 cgttgacagt aagaatgctg ttcgttctat tttttttgag aaaagctggt tttttgaatg
     4141 gcaattaaat gaaaaagaac gtatatgtgc ttgacgtgta gtgttcaggc gactagaata
     4201 ataagtactg caaaacaaag agtaagagga cgggagaatg catgatggag tttcagttag
     4261 accaagagtg gcggttacgt cccatcaaag gcgacacagg aaaaacatac ataggcatgc
     4321 gtgatgagga caaagtcttt attaaacgaa acacgactcc gatgttggct gctctttcaa
     4381 gggaaggaat tacaccaaaa cttgtttgga caaaacgaac ggggaatggc gatactttga
     4441 cagcacaaga gtggctggaa ggtcgcttgc tgactcctaa tgagattggt caaagaaacg
     4501 acgtgattga tgttttgtac catttacatc attcaaattc tcttaaaacc atgctgaccc
     4561 gtatcggtgg tcgtgtcatg acgccggaga agatgctgca aaaatatgaa aaagaattac
     4621 cggaagaact ccagaaaaat caatttctgc aaattgtcca tcgttttctt cgtgagcaga
     4681 tcccgtcaat agataaggaa aacttatcag tagtacacgg agatgtaaac catcgtaatt
     4741 ggttagtatg taaaaattat ttatatctag tcgattggga ttcaatcatg tttgcagacc
     4801 ctgcggtgga tattgcaacg attttaggaa attatgtgcc actgtctagc tggaatcagt
     4861 ggctgatcag ttatggcata cgcccgactg acgaaatgct tgaaaaattt cattggtatg
     4921 cggccatgaa tttgctccaa gaaatcacca gatattgcaa acgtgaagat catcgacgga
     4981 tgaacgaaga aattttacaa ttaaaacgaa ttttcagtgg ctgaggtttg gcccaaactc
     5041 tgcggagatt tggccagacc tttttaatta gaggaaagga atggagataa ataatgcgtg
     5101 tccgaaatcg tccgggagca gcggaaatgt tagcggctca cccgaatttt gtaattagtg
     5161 atccaacatt gtggaaggga aaatggaatg aattgtttga aaacgatcat ccaatccaca
     5221 ttgagattgg tatggggaaa ggccagttca tcactggaat ggcaaaagcc catcctgaaa
     5281 tcaattatat tggagtagaa atgcaggtca gtgttgtttc gattgcacta gacaagttga
     5341 tcgaacaacc gcttcctaac ctgaaacttc tacatgtgga tggatcagcg ttgacagagt
     5401 atttcgctga cagcgaagta gatcaaatct atctgaattt ttccgatcca tggccaaaaa
     5461 aacgtcatga aaaacggcga ttgacatata agacttttct tgctgtagat gaacagattc
     5521 ttcgtccaaa tggagaaatc catttcaaaa cagataatca aggattgttt gagtattctc
     5581 tggcaagttt ttctcaatat ggcatgatcc tcaaacaggt atggttagat ttacatcaaa
     5641 gtcaatttga aggcaatatt atgacggagt atgaagaaaa attttcttca aaaggtcaac
     5701 gtatttatcg agtagaagct caatttcaag ataagaccaa aaagaaaagt ctgtgaaact
     5761 aactttctgc tttcataaaa acattaatat ccataaataa atcccagaaa atgaacatta
     5821 cagatgtaat gtattttctg ggatttattt gatttaaaat gtatttattt catcggtttt
     5881 tccacaaggt ggaatcaatt ggaagcgaga aaatgaaaat aatcctttgt cggtgatctt
     5941 caattcgggt atgacagata atgttaagaa agaaagtgtc aaaaaaggat caaaggtttt
     6001 agctgctcct agttgatgtg ctttagttat taattcattc aactgttcat agacgatcga
     6061 aaaaggttcc tgtgtcatga ttccgcctat aggaagagaa acacaagcta tttcctgctg
     6121 attgttgaca acggtcatcc cgccaccttt ttgaatcaaa agattagcag catacagcat
     6181 atcctcgtcg tttgtcccaa cgacaactag attatgcgag tcatgggcaa tcgttgtcgc
     6241 tatcgctcct tgtttcagct gaaatccttt cactatgcct aatccaatgt ttcccgtttg
     6301 atggtgacgc tcgatcaccg caatctttaa ttggtctttt tcgattgaag gaatgaatcg
     6361 ttcgccttgt cggtccactt tttctaccaa atctttagtc actagactat tcgggataat
     6421 ttcgatcaca tgggcttgtg aagaagaaag aagcagctct aacgaatgtg gatttaatgg
     6481 ttgagcgttt agttttggca gacaacacgt atatgaattt gaatgatcag caaataaatg
     6541 gtcttggagt tgcccagatt gaacaactaa tgttccctta tagaaaactt catgaattgg
     6601 cagcttggta agatcgtctg ttaagaagaa atcagcttga tacccagggg caatcgcacc
     6661 tagtgttttc aaatcaaaac attctgctgc attcaatgtt gccatctgaa tggcttgtaa
     6721 tggatcgatt ccaagtgcaa tagcttgacg gacgatatga tcgattgatc cttcttttac
     6781 taaatcattg atcagtttat catcggtgac aaagaagcat cttcttgaat tttcaggtgt
     6841 gatcgccggt agtagcgatg ccagatcttt tgcaacggtc ccttctcgaa ccattaaata
     6901 cataccaaga tccaaacgtt ctttagcttc ttttgcagtt gtagcttcat gatccgtccg
     6961 aatacctgct gcaggataaa catttaactc ttccatgccg ataccagctg catgcccgtc
     7021 aatttttttc ttatgctggt gcatcaattg gatcttttct aggatgtctg tttcattatt
     7081 tgctactgct tgatagttca tgacttcagc taagcctaaa acttcgggtt tttgtaaaaa
     7141 aggggctaat ttttttgcat ttaaatttgc accattggtc tcaaaagggg ttacaggtac
     7201 acaagaaggt agcataaaaa agatattcat gagtgtttgt cttgcatctt ctatcataaa
     7261 ctcaagacct gtactcccag caatgtttcc tatttcatgg ggatctgtca ctacagtagt
     7321 aactccatga agcaaggata cttttgaaaa ttcgcttggt gataaaagtg agctttcgat
     7381 atgcacatgg ccatcgatga atcctggcac tagatattgc ccattagcat tatgtacgct
     7441 ttttccttcg tattcaccga ttcctacgat cattccttcg cagattgcta catctttttc
     7501 catgatttct ttcgtaaaga cgttgacgat cttagcatgc ttgatcacta ggtcagcagg
     7561 ctttttttta cttgctactt cgatatattt ccttaatgtt gtttccaatg gagtgcctcc
     7621 caagataaat ttttataagt ataacataaa ttcggttttt gccaatattt ttttgtaaat
     7681 tcattttatt tgaaacaaaa agatcaaaaa gacgtatgtt ttttgtggag gggagaataa
     7741 tggaaataaa acgattatcg gatcaaatga taagtgaaag ttttgccaaa catgcccaag
     7801 acgtatatat attgccagct tcagaagtat tttacatcta ttttcgctat ggaaaaaaac
     7861 gaacattctg gaagaaagtc tcttcggcag atggacagca actgatctca agatttaagt
     7921 atttgggaca gatggatatc ggagaaaaaa gaaaagctca gttaggtgca tttacttatt
     7981 ctttagaaaa acaggaagtt cgtctgcggt tgtcttctgt aggagattac cttcaacgag
     8041 agagtttagt gattcggcta ttatacggta cttttgaaac accccatcgt tgctttagtt
     8101 ctcgagattt tgcaactatt ttacagaaaa ccgtcagacg tggattatac cttttcagcg
     8161 gaccagtcgg atcaggcaag acttctctaa tgtatcggtt ggctttggaa gaaaaattgc
     8221 aagtgattac tatcgaagat cctgtagaga tagaagaacc gttttttctg cagctacaga
     8281 tcaatccgaa aatagcacag acttatgata cacttttgag actcgcatta cggcatcgtc
     8341 cagacttgct aatcattggc gagataagag atgaatcaac tgcacatgct gcggtaagag
     8401 cagcactaac agggcaccgg gtttttgcaa ccgtacatgc acgcaatctt gaaggtacat
     8461 tggtcagaat ccatgaactg acaaagaaaa aagaagagct atctgaatgt ttagctggtg
     8521 tcatttatca agaacttttg gaagatgcca atcaccatcc ttctgtttta tggagttatc
     8581 aatttatgga ggaagaatca gtaaaaaaat catgggagga aagttatgaa gaagctcagg
     8641 aaaatatttg gcagtcagaa ctattctaaa ggattaacaa gaagccagca aaaccagttt
     8701 gcacaaacca tgggagaact gcttttatct ggttttagtc tgcaagaatc cctttattta
     8761 ttactcacga tccgttcgtt tccacctgtt attttggcaa atatccaaca tcagctaaag
     8821 gaagggcaag cgtttagtga ggtactttcg caaataggat atggagcaga gcaactggta
     8881 cagatcgagt tagctgaacg tcatgggaat ctgccgacaa ctttgttgga aattgccaaa
     8941 cagtttcggc ttgttgaagg atttcgcaat gatttgaaaa agctgcttgc atatccgatg
     9001 ctattgctca cctttttgct aggtatcttg tttagtatgc ggttgttcgt tttgcctcag
     9061 cttattggtt caggaatggt catgcaagag cattggggta ttcagctgat acaagtcttt
     9121 cattggtatg ttctactatt catcctagcg gttactctat tggctttact agtaaggtat
     9181 cgtctgatga agttgtctcc tgttgatcag agtgaatgga taagcagaca attattgatt
     9241 ggaccgatat attccttgta tcaatcggct tatttgtcac tagagattgg aaagcttttt
     9301 catgaaggtt tcgaattaag gcaaatcata gtctgcttaa aggaaacgaa acaagaaagt
     9361 ctgattcagc atcttgcctc taagttgatt caaggattgg aggcaggtat gtcattggct
     9421 gagcagttcc agaattatcg ttttctatca gaagaattca gtaaaattgt tttacaggga
     9481 gaggcaaagg gaagtttagg taaagaactg attttttaca gcgaatggac aagaaaacag
     9541 cttttcaaac gtcttcatca ctggatgcat tttattcagc caatcatttt tttgggcgta
     9601 gcggctttga ttttattagt ttatgccgct gttttattac ctgtttacgg aagcatagag
     9661 gaggttttgc catgaaaaag agaaaaatat cttattatag cggttttaca ttgatcgaaa
     9721 tgctaatcgt cttactgatc atcagtgtat tagtgttgtt gttcgtccct aatttgtcgc
     9781 gttataggaa tcatgtagac caagaaagtc gtgaagcgat catccagttg gtagacacac
     9841 aaaaagagct ctatgcgctt caaaataatg gaagagttcc tactgtggag gaattgttga
     9901 atgaaggcta tatcaaacga gaacatgcag aaatctatca gcggccttga aggtaaggtt
     9961 ttagcatcag gatatacgtt gtttgaatca ctcttactga ttttattact tacaacgatc
    10021 ctttcttttc cagttctcgc attttctgca tggaagaatg aattggcagt ctatcaattt
    10081 ttcggccaat ttgaaaaacg aatctattct acgcaaaaaa tcgctattgt gaatcagatc
    10141 caaacaggct tttattggaa tagtgaagag aatcaaatca tttttcatgt tccgaatcca
    10201 gataaaataa attgggaagt attagatatt cctgatgaga ttaccttgaa acgccatgct
    10261 tctattactt ttgctgctag aaccgggaat gaaagttcac taaaagctta tcaattttat
    10321 tgggaagaaa aagagcggac gattacgtat caattccaga tagggagtgg tcgctataca
    10381 aaaagaattg aataaaacag gatttgtttt gttggagtcc cttacagcgc ttatgatcgc
    10441 ttctgtctgt gtctacttag tgagctttgg ccagctgttt ttgcttcagg cagaaaagaa
    10501 aagtggggag gaactgctat ttattcgaat gatttatgaa gatatcaaga cgcagcggat
    10561 gtatcacaaa agaccagagc gaagggaaga aatgatccca tacgatatcc aaattgtcga
    10621 taataatgga gtaatcgaaa aagtgtttgt caatatggag aaagaagcga tcagtattga
    10681 aaaaacaagt aattccagca tttacgctga ttgaatgtct aattggactg atgatattga
    10741 gcagtctatt gctcacattc aatcttttga ttcagcaaac catccaagta agtgaatttt
    10801 tgcagcgtaa agatcaaaaa gagtggctaa tatttttagc acaattagaa gaagaactca
    10861 agagcagtca caatgtctct gtgaaaaatc agcaactgca ctacacgatc gaggataaac
    10921 agtatatcat cgaaagatat caggcaatga tacgtaaaag aagaacttcc ggcggacatc
    10981 aacctatgtt aacaagtatc actgagcttc aattattgga aaaagaacac acaatttctt
    11041 tttatgtaca ctttgaaaat ggagaagatg gatatgccat atggacaaaa aacgatcagt
    11101 agaaaatgtt ataagggctc tattttattt tctgtcttgc ttttatttct tttatgtacg
    11161 tttttattga tggcagcatt agaaagctac cgtttgtcaa tggatcttaa tatacgaatc
    11221 aaaaattatt atatagcaaa aataatgaag cagatggctt tatcggaaca gtctacgctt
    11281 gccgaaagtt cggaaggagt tttttactac acaactggat ctgtaacata tcagtgggta
    11341 caacagtccc tattcttaga ggtggaagtc tcaccgttta tctttcggtt cacagaagaa
    11401 gtaaaaaatg atacagatac tagtacagaa tgatggaatg ttcgtgaaaa cgccctcttt
    11461 tctgttataa cactgttttt aataaaaaaa tgtttgccgt ttcacaaata aaaaacagtg
    11521 aaaacgattg aaattttgtc aattgttcga tagaattaaa caggtgaaaa aattgttata
    11581 atatatctag aaatgaggtg caccatgtta ccagaaaaaa tggaacaagg gtttaatcaa
    11641 aacctggaag ctattcagct tttacagaat gcattgggaa cttccttttt agaagcctat
    11701 gtcgaaaatg cagaaaattt aatagatgat tatcaagtac gtgtggtgga tggagtgccg
    11761 acaaaagaga caacgcaacg gatcacagct ctttatgaag agttgaagaa actttctttc
    11821 gagccagaag aatggcgcag actgtctcaa ttacttttat tgaagggcag ccagacagaa
    11881 catttgcagg cgaaccatca actcactcct gatagtatcg gttttttatt tgtttttctt
    11941 attgaacaac tatacacaaa taaaaaagca ccggttaaga ttctggatat tgcggcagga
    12001 atgggcaact tgttattaac agttctttta aacctatcga atgcggggta ccaaacagaa
    12061 ggaattggtg tggatattga tgatacattg ttggctgtcg cagcttctac aagtgatttg
    12121 acacaagcaa atgttcaata ctttcatcaa gacgggttgc aggaattatt aatagatcct
    12181 gtcgattttg caatcagcga tttgccaatc ggttattatc cgaatgacga aaaagcaaaa
    12241 gagtttttaa caagtaccga agaaggccat agttatgcac atcatttatt gctagagcaa
    12301 tcaatgaaat atgtgaagcc ggatggtttt ggtttgtttt tgatgccgag tggattttta
    12361 gaaacggatc aaagtgaaga aatcaaaaaa tggtttaaag aagaaggtta tcttcaagga
    12421 atgattcaat tgccagatga attgttccgt aataaacaat cgcaaaaaag tattttgatc
    12481 ttacagaaaa aaggaccaca agcacaacaa gtaaaagaag tcttgcttgt gaaacttgct
    12541 tcattaaaag aaccagagaa ggtgacggaa tttttcaacg agtttaaaaa ctggaaatca
    12601 tctgctctgt aatcattcaa cgagaaggag agtcatatgt ctaaaacaat tgcaatcaat
    12661 gctgggagtt caagtttgaa atggcaatta tatcaaatgc cagaagaaac cgtagttgcg
    12721 aaagggatcg tcgaacgtat cggtttacaa gattctattt ttaccatcaa gtacggcgat
    12781 aatcaaaaat tcgaacaaat catggatatc gaaaaccacg aagtagcagt aaaaatgctg
    12841 ttagatcagt tgattgaact gcaaatttta agctcttatg atgaaatcac cggagtaggg
    12901 caccgtgttg ttcacggagg agaaacttat ggggattcag tagtgatcga tgagaaagta
    12961 atggaccgca ttgctgaatt agcagaattt gctcctttgc ataatcctgc aaacttaatg
    13021 gggatcaaag cgtttaaaaa gattttacct gacattttga gtgtggctgt attcgataca
    13081 tctttccact caacaatgcc aaagcaaaat tatttatata gcttaccggt gtcttattat
    13141 gaagatttca aagtaagaaa atatggcttc catggcacaa gtcatcgtta tgtgtcggaa
    13201 cgtgcggcaa aattattgaa caaaccgatc gaagaactaa aaatcatcac ttgccactta
    13261 ggaaatggtg tatcgatcac agcagtcgat ggaggtaaat ccatggatac ttctatggga
    13321 ttcacaccat tagctggggt gacaatgggt acacgttcag gtgatatcga tccagctgtt
    13381 ctcccatatt taatggaaaa attagagatt gatattgatg aaatgatcaa tgttttgaac
    13441 aagaaatctg gtctgctagg cctaacagga ttgtctagtg atatgcgtga tcttgaaaag
    13501 aactatgaaa aagaacatat tcgtttagct tatgacattt tcgtggaccg catccgaaaa
    13561 tacatcggcg gttatgtgac aacgatgaat ggtgttgatg caattgtctt tactgctggt
    13621 atcggcgaga atgacggaca tgtacgtagt gaaatcatca aaggtatgtc ttggtttggt
    13681 tgtgaaatcg atccagcgtt gaatgaattg cgtggtgaag aagtagatat ctctacaaaa
    13741 gaatcaaaag taagagtatt agtgatccca acagatgagg aactaatgat tgcccgtgat
    13801 gtggagcgtc tgcgcggcta agccaaagca ttcgttagga taaaagatga aacgcatgca
    13861 agagggaatt cttgcatgtg ttttttttgc ggagaagacc gcaaaatggt aatttaactt
    13921 caatttccct tcttttttac aggatcttct tagggaattt tgcttggaaa agtggtcaaa
    13981 agggaaaaga ctggcatttt atttattgat tttcaggaaa atcccaatat tttattttca
    14041 ttcatcttta taagggacat tacatatgta aaaagaaaaa acatttttag atcagcctcg
    14101 tgggctgtcg actttattct tcgctttatg tttagctaga aaaccgatcc gaaacattca
    14161 ttgatcgaat aataaaaact tgattttcca cctgtacttt gcctgaatcg tgaaagcaca
    14221 ggtatgaaaa tcaagttttt tgttgcgaaa aaacgtccta gtcaatcagt tggccgagcg
    14281 gctggcggct gatctgctcc tgatcaataa cgagtgcttc ttggaagtgt tgctgcaaaa
    14341 agtagcggtc atggctgact gctaggagcg ttccttgata gtcttgcagc atttcttcaa
    14401 tttcttctcg agcatagctg tcgaggtgat tggttggttc atccaaaatc aggacgttga
    14461 ttttttctaa aaagagtttc agcaacgcca aacggatttt ttcaccaccg gataaatctt
    14521 tgatccgttt acccacatcg ctttgataaa agccactttt ggctaattgc cgtcgagcga
    14581 cttcttcgtt tccagtcaat gtgatggcgt aagccagcaa acggctatcg ggatcggcaa
    14641 actgcagctg ctgcggcaaa taaccgattt gcaagctact acctaatttg atggtgccac
    14701 cgtaaggctt ttcctcaccg agtaataatt tgagtaaggt tgattttcct gcaccattgt
    14761 cgccgatgat ggctaaatga tctccacgat agactgcaaa actgctgtct ttgaatagta
    14821 cttgatcagc gtactgctgg tgcaagtttt gaatgatgaa aacttctttg ccagattttc
    14881 caccattaga caagctttgc agccgatttt tcgggggagg tggcggtttg acgagtgtca
    14941 gtttcgccag gcggcgttcc agttctttgg cttttttgaa gaaggactca ttgtctcctt
    15001 catgtgccca ctgacgaaaa cgacgaatca tgactttcaa ccgctggact tctttttgct
    15061 gcagttcgta attttttgtc agctcagcca agcgagcttc tttcaagact cgaaaacggc
    15121 tgtagtttcc gggatactca atcaatgcac cttcttccag ttcccatgtt tttgtggtga
    15181 cttgatcgag aaattgccga tcatgagaaa cgaccagaac cgattttttt gtattctgta
    15241 aatagttttc caaccagcga atactgttaa gatctaaatg attggtcggt tcatcgagta
    15301 aaagtaaatc ggcatcggct gctaaaattt tggctaaagc gactttaact cgttcgcctc
    15361 cgctaagttc tgttaaccgt gcttcctgac ggtgtggaat ccctaagcct tgcaagatcg
    15421 ctgcaatccg gtcttctaat acgtaaccgc ctagttcttc aaagcgatgc tgcagctcac
    15481 cgtaacgggc cagacacttc tctaagtttg tatctggttc tgtcatcaat gcttcgtagc
    15541 gactcatttg ctgtttgagg tcctgtatct cagcggcaga atggagcaag tagtggttga
    15601 cggtcgcttc ggaaactgta agttcttgtt cgaccgtccc gatctttaag ccttttttgc
    15661 gactgataac accgctgtcg acaccttctc tgccggtcaa gatttgtaaa aaggttgatt
    15721 tgccagttcc gttgataccg actaaggcaa ttttttcacc agcttcaatt tgacaggata
    15781 aatcctcaaa taatggattc ccgccgattg tttttttaat agaaattgct tgtatgatca
    15841 tgatctctct ccttgagacc actcaaaaag gccatggtta tccatggcct gtgttattta
    15901 aactcagatt atcatgagaa aaataccttg agatggccat tgattttacg tgaattcaac
    15961 tgttttggac aaacttgtcc cgtcaacagc aactgtaaaa ccaattgcat ggctaaatgc
    16021 gatatggtat cgttggtaat tttcattact tgttatttta gtcatgcgca tcatagtatt
    16081 ttccctcctt cgtgtagttg tcttttccag tgtacctgaa agtgtcagaa agttcaacta
    16141 gcgctgacat ttacttaata tttatcgatg tgtaattctg tcagagagct ttttttatct
    16201 gactgagggt aatgtctcgt ggaccacatc attgtattct gagctaaacc agcgttcagg
    16261 cgaaatcata tggtgtttga taaaaaactt tgtctacatg acttcctttt gccatttgct
    16321 taataccgtt gcattaaaca gctcttctct ttggaaatct caccaacatc gcgttcagga
    16381 gtatcgttgt ggttgcaatg gcaagcggta gcctttcatc aattcttgaa tgatttaccg
    16441 aatgtagcac ttgccttctc gcggtacccg aacccgaaat aaaattttag tttggcgata
    16501 aaatcggtat ccgccatcga tacttcatat tttttcgtat cagattcatc ggaaacttcc
    16561 acattgacga accaataagc tttggcatgc ttaggtcgtt ttaaaccaca ccagggcgac
    16621 taatcgccct ggtgttcact tttttttatt ttacttgaac tcattgactg ttttcccttt
    16681 attttaaaca ttataaagac cgatgagtgc ttgccgcgtc ttttgttttt atcacggttt
    16741 tttgtgcaaa aaaacctgcc gatagttggc aggtcgtcta cgtgttaagc tttggtgtgg
    16801 tctttagctg gcaattggtt ttctaaatca gttcggacaa caagcacatc gcaagctgcg
    16861 tttctaataa catattcaga aacagaacca ataaataaac gttctacagc attcaatcct
    16921 gtggctccta acataatcaa atctacttga ttatcttctg ggatttctct ggcaataatt
    16981 tgttttggtg agccatattc tacgacagag gttacattat tcaagccagc tttcttcgca
    17041 ttgctttcat aatctgccaa tgtttgcttt gccatttcag tagcttgttc tgcaagcatt
    17101 ccatcaaagg atgaaacggt ttggaaagaa cgtgtgtcaa tgacatgtgc taatagaagt
    17161 tctccgttat ttcggatagc tacattgacc gcctttttaa aagctaattc agcttcatca
    17221 gaaccatcta cggcaaccat gatttttttg tattgttgta acataagcat tcactcctca
    17281 agtcaatcgt attgtactct tttattgtag aacactttag ggaaaaagag aattatttac
    17341 tgctttggtt cagcaatttt ttttgcaaat cggatactga aggtggcaga aacaataatt
    17401 acgatcagta aaaagaccaa ggcaataaag cgttgattga aaaaagctgt taaaataccc
    17461 attacgccta aaacagcata tgcagctccg taaaattgta ggaatccttg atttttatca
    17521 tttttgttga tcaatacaaa aaagatatcc tgtttattaa ataaataata gctaacgaat
    17581 aataatacta aagtggcgat aatcattaaa atcctaatca tgaacaaatc ctccaaaata
    17641 agcaacaaat agaaaaagca atttgccaag agcaaattgc tttattcttt aaaagatggt
    17701 aatctccgtt aatgccgttg tttgtcctgt agtattgatc ccgcgaattc aagcaggtgg
    17761 gtcccatggt cgtagcttcg aactaccaaa tgataaggca tgttaccagc agtgacacaa
    17821 gacgggtccc aagatatcaa taaaaatgtt cggtcaacac acaaagagga caattcgaac
    17881 atcacagatt tcccacctct atagtagcat atgaatttaa aaagagcaat gagagagctc
    17941 gcagaaacag aaccgttttc ttgtctagtt ttttggagga tgctttttcc actcttttat
    18001 acggtaatac tgttgaccca gagcctgttc atatttccct gtatcttttg gctgataata
    18061 ctgagcattc ttcagtttat ctggtaaata ttgctgattg acccaagcct gatcaaaatg
    18121 atgaggatac tgataaccca cgccacggtt gagtgatttc gcacctttgt aatggctatc
    18181 tctcaaatga tcaggaacat ctccagcttt gccctctcga atatcagcaa gtgctgcatc
    18241 taatgccatg taggcagaat tggattttgg cgacaagcaa agatcgacga cgacgtctgc
    18301 tagtgggata cgtgcctcag gcaatcccaa tttttcagca gctaatacag cgttcactgt
    18361 acgagccgca gcagcaggat tacctaaacc tatatcttca taaccgataa ccatcagacg
    18421 ccggcaaata cttgccagat cacctgcctc aactaaacgg gcgagataat gaagtgcagc
    18481 atccacatca cttccacgaa tcgatttttg aaaagccgaa ataacgtcat aatgagcatc
    18541 tccatttttg tcatgggtaa gagcttttct ttggacacat tcttcaatga tcgacagtgt
    18601 aagatgaatc cttccttctt tatctgaagg agtcgatagt gtagccagtt ccagcccatt
    18661 caatgcactc cgcaaatcgc cgttcgttgc acgcgaaagg tgaagaagag catcttcgtc
    18721 taactggatt gcttgttgtc caaggccgcg ttctttatcc cttaaagcat gttcgactgc
    18781 caactggatg tcttgttctg ttaatggttt gacttcaaag atctgtgtac ggctgcggat
    18841 cgctggattg atggtaatat aaggattctc agtagtcgct ccgatcaaga tgattcggcc
    18901 actttctaaa tgaggaagca gaaaatcctg ttttgtttta tctaatcggt gtacttcatc
    18961 caataagagg atcactgtac cactcatttt tgcttcttcc gctacaactt gtagatcctt
    19021 ttttgaatct gtagcggcgt ttagcatgcg aaatgcataa ttagtagagc cggcgatcgc
    19081 acttgcgata ctcgtttttc cagtaccagg aggtccatat agaatcatgg aagagagcat
    19141 gcgagcatcg accatgcggc gtatgatttt tccttccccg actagatgct gctgaccaac
    19201 gacttcatcg atcgttcgag gtctcatgcg ataagccaat ggctgttgca taggattttc
    19261 ctccttcttg tttttacgtc ccttaattat atcatattta gcaagatgcc tagaaagaac
    19321 agccttctgt tgttttgttt tcatagctta tccaactaat attgtgtatg ataaagtagg
    19381 tgagaaaaat gacggataaa caaaagatag atgaattttt ttggaataaa acgacgccag
    19441 aagtggcacg ggatttattg gggatgtatt tggagcatga cacaccagaa ggaagattag
    19501 ctggatatat tgtagacgcg gaagcatacc taggtccaga agacgaggcc gcccatagct
    19561 atggtttaag aagaacaccg cgtgtgcggg caatgtatga aaaaccaggt acgatctacc
    19621 tttacacgat gcatactcat cggattttga acatcattac tcagccagaa gggattcctc
    19681 aaggagtaat gatacgtgca atcgaacccg ccgcaatgat tgatcaaatg agtaaaaatc
    19741 gtggcggaaa aactggtcca gatatcagca acggtccggg aaaattagtg gaagcattag
    19801 caattcctca agaactttat ggtcagtcta tagcagatag ttcgttacgc ttagtttttg
    19861 agaaaaaaaa gacaccaaaa aagatcaatg ctttgcctag aatcggtatc ccaaacaaag
    19921 gtgtatggac agaaaagccg ttgcgttttg ttgtgtcggg aaatccttat atctctttac
    19981 aaagaaaaaa ccaaatcgag aaagattggg gttggaggaa agaaaatgaa aaagaaggat
    20041 ctattaacat atttagatga aataattgaa aaacaagtga cagactatga tgtagcttta
    20101 gattgggata caaaaaatca tacgatcgag atcgttgttc gcttgtttgc agaaaataaa
    20161 gcacaatttg agattgatga tgcagaaggg atcgtttcgc aagaaccaat tatcgaattt
    20221 gaagacggcg tacttctttt taatcctcag aaatctgttt ttgatgaacg caattatcta
    20281 gcagtaatcc cttatgaagg aaaaaaaggg ttggcaaaat cagtagctga ttctttagtg
    20341 gaatatctaa atgaagtatt agctcaaggg caaagcgatt tgcttgattt tttggatgaa
    20401 gacgatgacg aagctgtatt cgagcttcac tgggataatc agcaactagc agaattagta
    20461 gaagtaaaac agcaaaatga agcagatact tatttaccgt acccaagtta ttaaggagtg
    20521 acagatatga aatggaatga agtaaaagta gaaactgaaa gtgaagcagt cgaagcagtt
    20581 gctaatattt tgatggaggc aggggcgagt ggtgtcgcga ttgaagattc tttagatgtt
    20641 gaacattttc agtcggatca atatggtgag attttagata aaaatgattt tacatcgctg
    20701 aaagaaggcg cactagtcat ggcttatttt ccggaaacga ctttcttacc ggaaatcttg
    20761 ccttttatca aagatcgtat cacacaatta cctgagtttg gtctagctat tggaaaaaat
    20821 aaagtaacag ttagtgaagt agaggaaagc aactgggcaa cagcctggaa gaaatactat
    20881 catccggtgc gtattacgcg aatgctgacg gttgcgccaa gctgggaaaa ctaccagaca
    20941 gaagatcctc tagaaaaaat tatcacacta gatcctggta tggcatttgg cacaggcact
    21001 catcccacga cttccttgac attgacagca ctagaaacag tcttgcgtgg tggtgaaaca
    21061 ttgctagatg tgggaactgg gtcgggcgtg ctaagtattg cagcaaaata tcttggtgca
    21121 aaagatgtct atgcctttga tttagacgaa gtagccgttc gttcggcgaa agaaaatatg
    21181 gatatgaatg aaatagccaa agatgtccat gtatcagcta acgatctttt gacaggaatc
    21241 gagattgaaa gtgatgtaat cgttgcgaac attttagcag atatcatctt attgatgatc
    21301 ccagatgctt ggcgtttact gaagcaaaca ggcacgctga tcgtttcagg aatcattgaa
    21361 gagaagaagc aaatggttct ggatgccatg ttagaacaag ggtttatcgt ggatcaaatt
    21421 ttccagcaaa aagactggta tgcaattatt ttgaaaaaac cagaggtgga atagatgcag
    21481 cggtattttt taaaagaatc atatgaatca aaagactatt ttgttttaga aggggaaaac
    21541 tatcaccaca ttgtacgggt tatgaggatg gaacccgagg atgaagtttt tttggcattc
    21601 aatgatcaaa tagccattgt tgcagaaatc acggagatta ctgaagaggc tgtttatctg
    21661 aaagaaatta aaaaagaaga aaatcaaaag gaactgccaa gttcgattac catagcgagt
    21721 ggctatccta aaggggaaaa gctggattgg atcgttcaga aatccactga attaggagcg
    21781 caagcttttc ttggtttccc ggcatcagcc tctgtcgtta aatgggatgc aaaaaaacgt
    21841 atgaaacgac aacaacggct tgaaaagatt gctcaagagg cagcggaaca atcccatcgg
    21901 cagatcgtgc catcagtaga gttattggaa acgaaacaag atttatttga gcggctagat
    21961 gattatgacg tggtcttggt tgcttatgag gaatcagcaa agcaaggcga aaaatcaaat
    22021 gcagccaaaa ttcttagtga aacaaaacca gatagtcgaa tcttagctgt ctttggacca
    22081 gaaggtggat tatcccgcga tgaagtcgat tattttgtag aacacaaagg gatactttgt
    22141 ggattaggac caagaatcct tcgtacagaa acagcacctc tttatttatt aagtgctgct
    22201 agctatcaat gggaattaat gaatccttct ttcagctaac gttcttcatt aataaaagag
    22261 tatcgacaga aagaattgaa aaaatagtca acaatttgta taatagaaac aattatttat
    22321 acaatggata cgaaaaatcg tttgaaaaag cttttaaaaa gcgaacattt ccgtaaaaaa
    22381 acgtataact gcacggattt tgggacaatt atcaaacaga tatttgtccc gattcccgtt
    22441 ttaccgaaaa aagaaagggg gatcgattcc tgtgacaaaa gaagaaattt taacgggacc
    22501 cggtgtcata aagctcgtta gtcaatacat gggtcccgaa catgtagcat ttgttgagaa
    22561 agcatgcgaa tacgcgactg ctgcacatga cggacagttt agaaaatcag gcgaacccta
    22621 cattattcat cctatccaag tcgcaggtat attagcagat ttaaaaatgg atccccatac
    22681 agtggctaca ggcttcttac atgatgttgt tgaagataca gaaatcactt tagaagatct
    22741 gagagaagaa tttggcgatg acgttgctat gttagtggac ggcgtaacca aattagggaa
    22801 aataaaatat aaatcccacg aagagcagct agcagaaaac caccgaaaga tgctgctagc
    22861 aatggctcaa gatttacgag ttatcatggt caaattagct gatagactac ataacatgcg
    22921 tacgttgaag cacctgcgag aagataagca aagaaggatc gctcaggaaa ctttagaaat
    22981 ctatgcgcct cttgcacatc gtctagggat cagccggatc aaatgggaat tagaagatac
    23041 agcacttcgt tatctaaatc caaaacagta ttaccgtatc gtccacttga tgcagacgaa
    23101 gagagaagaa cgtgaaaaat acgtaagtgg tactgttgaa gatattcgaa tagcgacaga
    23161 agagctgggg atttttgcag aaatctatgg acggccaaaa cacatttatt caatctatcg
    23221 taaaatgaaa gatcagaaaa agcagttcaa cgaaatttat gacttgctag ctattcgagt
    23281 gatcgtagat tcaatcaagg attgttatgc tgtattagga gcaatccaca caaaatggaa
    23341 accaatgccc ggcagattta aggattatat tgccatgcca aaagctaata tgtaccaatc
    23401 tttgcatact accgtgatcg gtccggcagg aaatccggta gaaattcaaa tccgaacaca
    23461 ggaaatgcat gaaatcgctg aattcggggt tgctgcacac tgggcctata aagaaggaaa
    23521 aaatgaaaaa gtagaaccag atggtatgac gaaacaatta agctggttcc atgagatact
    23581 cgaacttcaa gacgaaagct atgatgcttc tgaatttatg gaaggcgtaa aaggagatat
    23641 ctttagtgat aaagtctacg tcttcacacc aaaaggagac gttactgagt taccaaaagg
    23701 atccggacca ttggactttg catacagtat ccatacagat atcggtaaca aaaccactgg
    23761 tgcaaaagta aatggcaaaa tggtgcagct tgattacaaa ttgaaaaacg gagatatcat
    23821 tgagatcatg acttctccaa attcatttgg cccaagtcgc gactggttga aattagttgc
    23881 tactagcaaa gcaagaaata agatcaaacg tttcttcaaa gcccaagatc gagaagaaaa
    23941 tgtgatcaaa ggccacgaat ccgtggtcaa atgtattaca gatctaggat ttacgcctaa
    24001 agatattttg acgaagaaca aactgcaaga agcactcgat cgttttaatt atcaaacaga
    24061 agatgatctc tatgcagctg tagggtatgg agaagttagc cccttgacga tggccaatcg
    24121 tctgactgaa aaagaacgta aagaacaaaa aatcgagcag caaaagcaag aagcagaaga
    24181 aatcatgaat cagccgaaaa aagaacctga caaaatgaaa gtacgtcatg aaggtggcgt
    24241 tgtcattcaa ggggtagaaa acttactaat tcgtatcagt cgctgctgta atccgattcc
    24301 tggtgatgat atcgttggtt atatcactaa aggcagaggg atatccattc atcgtcgaga
    24361 ttgtccgaat gttcagcctg acaaaccaaa tgtagcagaa cgtttgattg aagtcgaatg
    24421 ggaagataca tcgaatacac gaaaagagta tgatgcagat ttggaaattt acggctataa
    24481 tcgttcaggc ttattgaatg atgtacttca aacagtcaat gcgctaacga aaaatctcaa
    24541 cagcgttgaa gcacggacga ataaagataa aatggcgacg atccatttga cggttggtat
    24601 ccagaattta tcccacctaa agagtatcgt ggataaaatc aaagcagtac ctgatgtcta
    24661 cagtgtacgc cggacgaatg gataggagga cagatatgag agcagttgtt caacgggtaa
    24721 gtaaagctgc tgtgtcagtc gatcagcaag aaattggaaa aattggctac ggcctacttg
    24781 ttttattagg cattcatgaa accgatacgc aaaaagatgt ggactatctg gtaaaaaaaa
    24841 ttgcacaaat gcgtattttt gaagatgaac aaggaaaaat gaatattagt gtagaagatg
    24901 tgggaggaca aattttaagt atctctcaat tcacactgtt tgcggatacg aaaaaaggaa
    24961 atcgaccaag ctttgtggaa gccgcacgac cagaaacagc tattccttta tacgaatcat
    25021 tcaatgaagg aatcagaagt cgcggcatca cagtcgctac cggacaattc ggagcagata
    25081 tgtcggtttc tctcgtcaat gatggacctg taacgatcat tattgattct aaaaacaaat
    25141 aaagtaatct ggttttcact agtaaaaact atgaaacacg tcgcttaagt tagactgata
    25201 aactctaact taagtggctt ttttgtctgc aaaaagcgct tcttttgtca gcagtcggaa
    25261 aaaaagttaa gcttaaatta tacaagttat tttttatagg aggttgctga agatgaaaga
    25321 agtaccagta gtagatatca aaatcacaga tttaaaaaaa ttgtatcaaa aaggatacaa
    25381 catgttggag gagttacgcc atgaagcgga cgctcccgtc gtcaaagcaa agattttcaa
    25441 taaagaagct atcacgatct acggatcatc agcagcaaaa gtattttatg atccaaggaa
    25501 tttcaaacga aaaggtgcta tgccaaaatt agtattgaag acactttttg gtcaaggtgg
    25561 agtacagact ttggatggag ctgctcatca ccatcggaaa aatattttta tggatctaat
    25621 gacaccggaa agaatggaag attatcatcg tatcttagat aagaatctga cacaagcact
    25681 tgaagcacag catggtcaat ttgaactatt tgatttaagt aagatggttt tctttacatc
    25741 tatttgcgag tgggcaggta tcaatttatc agcgatttct aaagatgagg tcgaaaaatt
    25801 agcagaatat caaatctcta tgatcagcgg aacgtttact tctccgattg atcacataaa
    25861 aggtgtcgaa aatcgcaaaa aatcagaaaa atgggcgcaa ggcttgattg aagaagctcg
    25921 acaaaatcct gtggctggaa aagaaaatgt ggcattatat gcttttgcca atgccacaga
    25981 tttagatggt cagcttttac ctctggaagt ggcagctgtt gaattattga acatcatccg
    26041 tccaacggtt gctctaactg tgtgggcggc attgatggga catgcacttt tcagtagacc
    26101 agatttgtat cagcaattaa aaaatgactt ttcgacgtta caagatccgt ttattcaaga
    26161 aatgagacgc tattatcctt tcttcccaat gctacctgcg atttcgctga aagaagtaga
    26221 agtagatggt tatcgtatac cagaaggcag ttgggttatt ttagatttat atggaacaga
    26281 ccatgatgaa cgaacagttg aagcgccaga ttcctttatg atcaaacggt atgtagggaa
    26341 agcaaaagat atttcctata aagaagaata tgagatgatt gcacaaggcg ggggaaattt
    26401 tcgacaaatg catcgctgtg caggagaatg gatcactctt catagtctac gtgtgttttc
    26461 cgatcagcta gtaaataagt ttgagttctc tgtacctgaa caagattgga cgattccatt
    26521 caatcagttt ccgacttatc cgaatagccg agcgctactt tacaagaatt agattagcat
    26581 aaacttatcg aaaaaaagga agatcaaaca gtgctgatct tccttttttc atattactat
    26641 aaattgataa ggtcaattga tcaaaatcca cgaaatgctt catcaatggt ttgataatct
    26701 tcattggata aatgcaaatc taaagcttgg acattgtcag atacttgctc tggacgctta
    26761 gctccaggta taactacaga cactcgtgga ttcttcatgt accaagctaa aacaagttgc
    26821 gcaggagtgg cttggtatct tttagcaatg gggcgaagta catcgacagc ggttaaaatt
    26881 tctctgaaac gttctccttg gaaatctgga tttctttttc gaggatctcc ttcaccaaat
    26941 tgtttttcct caccaagttc atattttcct gtcagcaaac cggaagcaag aggaaaatag
    27001 ggaacaaaac tgattttgtt tttttcaaga taagggaata attctttttc agcctgccga
    27061 tggatcaaac tgtatttatc ttctactaca tcgacatatc catctgcatt cgcttctttc
    27121 aattgttcta acgtgaagtt tgacacaccg actgctcgga tttttcctgc ttcttttaat
    27181 tcgtgcaatg tagcaactga ttcatttttt ggtgtgcttt catccggaaa gtggatataa
    27241 aaaatgtcga tgtaatcagt ttgcagacgt tttagtgcat cttccaccga ttgtttgaga
    27301 aactcaggag aattatcaaa tgttcgccct ttatttggta catgagcagc ttttgtagcg
    27361 atgacgacac gtgagcgatc atattctttt tccttcagta cctcgccaat cagttcttcg
    27421 gaacggccgt ttccgtaagc ataagcggta tcgatcaaat tgatcccgct attcaaagct
    27481 gtacgaacta cttgttttcc tgtctcatct tccaaaccgt caaaaagatt atgtcctcca
    27541 acggcatttg ctcctaatcc aagctgttct gcgtagactt gtgaatgtcc gattcttatt
    27601 tctgccatag ctgattcctc ctttttgtct agtctaaaac aaaataccaa aaagctgaac
    27661 taaaacgttt ttgtgagggg aaatagtcag atatctcttg actttgagac tggtttttag
    27721 taggttataa gtaatatcga atgtcaatga aagagcgagt aagtttttga aactttacaa
    27781 gagaggatca tcgaggctga aaatgatcta aagtttcatt agcctaaaga cactctggag
    27841 atggacgagt gaaaagccgt cccgcgtacg agcgttattc gtaagaggaa agagaaatct
    27901 ttcaaaatta ggtggtaccg tgtatgaatt tcattcaccc ttgttcatga tgaacaaggg
    27961 tgattttttt atttacatag ctaagaaagg gagagaaaac tatgagtttc caaagaccaa
    28021 aaggaacaaa tgatattttg ccaggcgaat cagaaaaatg gcagtttgtc gaagaaacag
    28081 cacgtttatt attcagagat tatcagtata atgaaatgcg tacaccgatt tttgaacact
    28141 atgaagtgat atcccgaagt gtaggggata caacggatat cgtttcaaaa gagatgtatg
    28201 atttttatga caaaggggaa cgccatgtga cgcttcgacc agaaggtaca gcaccaatcg
    28261 ttcgttcttt tgttgagcat aaattgttcg gcccagagta tgcgaaaccg ttcaaaactt
    28321 tttatatggg accaatgttt cgctacgaac gccctcaaaa aggacggtta cgtcaattcc
    28381 atcaaatcgg agtagaagca tttggatcag aaaaccctgc aactgatgtg gagagcatgg
    28441 tgatggcact tgatttcttc aaacagttgg ggatcacgca aatccggcta gtcatcaatt
    28501 cattaggtga taaagaaacg cgtcaagcct atcgtcaagc attgatcgac tatcttttac
    28561 cttttgaatc agagctgagt gaagactcta aacgccgcct tcatgaaaat ccattacgcg
    28621 tattggacag taaagacaaa cgagatcaaa aatttgtggc agaagctcca tctatcttag
    28681 attatctaag cgagcctgct caaaaacatt ttgataccgt tgtttccatg ctggatgcat
    28741 tggctgttcc ttatgaaatc gacagtaata tggttcgcgg actagattat tacacacata
    28801 cgatttttga aatcatgagt gacgcaccaa aaatgggggc acaagcaacg atttgcgcag
    28861 gcggacgtta tgacaatcta gtggaagaac taggtggtcc ttcaacacct ggcttcggat
    28921 ttgcaatggg tatcgagcga ttactcttga ctatggaggc agaggaagta gttatccctg
    28981 catttaatga gttggatgct tacgtggtcg cactcggaga cgaaacaaat atcgaagcat
    29041 tgaaagtggt ccaagcgatt cgaaactttg gtttttcagc tgaccgcgac ttcatgaacc
    29101 gtaaagcaaa agcgcaattt aagacagcag ataaagcgaa tgccaaatta gtattggtga
    29161 tcggtgaaga tgagcttgct agtcaaacga ttaatgtcaa agcaatggca agccgaaaag
    29221 aaaaaagttt tccattagaa gagatatatg aacattttga tgaagtctat gatgaaatga
    29281 ctttattcga gtaggaggaa aaaaataaat ggcacaaaga acgatctatt gcggattagt
    29341 ttccgaacaa caattagaac aaacagttac attaaaagga tgggtacaaa aaagacgaga
    29401 ccttggggga gtaatcttta tcgacctacg tgatcgtgaa ggaatcgttc aaatcgtctt
    29461 taatcctgaa atcaacaaag aagcatggga aatcgcggat aaatgtcgca gtgaatacgt
    29521 gatcgaagtg actggggaag ttagaagacg cggagaaaat gcagtaaatc ctaaaatggc
    29581 cactggtgaa ttcgaagtga ttgcaagtga aatcgtgatt ttgaatcaag caaaaacccc
    29641 gccatttcaa attgaagatg atcaagcaat cagtgacgaa atacgtttga aatatcgtta
    29701 tttggatctg cgtcgtccaa aaatgactaa aaacatcaaa ttaagaaatg cgacaacaaa
    29761 agcgattcgt cattatttag atgataatga ctttctcgat atcgaaacac cttacctagg
    29821 gaaatctaca ccagaaggcg caagagacta cctagttcct tcacgtgtcc atgctggaca
    29881 tttctatgcg ttgccgcaat ctcctcaatt gtttaaacaa ttgctgatga atgctggatt
    29941 cgaccgttat tatcaaatcg ttcgttgttt ccgcgatgaa gatttacgtg gagaccgtca
    30001 gcctgaattt acgcaagtag atattgaaac aacgttctta acagcagaag aaatccaaac
    30061 ttacacagag ggattgattg cgaaggtaat gaaagaagtt cgcggtatcg aagtcacatt
    30121 gccatttcct cgtatgacct atgatgaagc aatggctcgc tacggcagcg acaaaccgga
    30181 tacacgtttt gatatggaat tgatcgatct aagcgataca gtcaaagaag tagaattcaa
    30241 agtcttccaa atggctcttg aaaacggcgg tgtcgtgaaa gcattgaatg ctaaaggcgc
    30301 tgcagatcgc tactcacgaa aagacatgga tcagttaggt caatatgtag gacaattcgg
    30361 agctaagggg cttgcatggc tgaaagtaga agaagacgga ttgaaaggtc caattgctaa
    30421 attcatggga gaagcaacag aagcaatcat taaagcaaca gatgcaaaac caggtgactt
    30481 gctgatgttt ggcgcagata aaagtgaaat cgtcgctgct gcattaggtg ctatccggac
    30541 acgtttagga aaagaattag gactaattga tgaatcgaaa ttcaatttct tatgggtaac
    30601 tgattggcca caatttgaat tttcagaaga agaaggtcga tatgtctctg ctcaccatcc
    30661 attcacgatg ccaaaagaag aagatatccc gttattggct gaagaccctg caaaagtcta
    30721 tgcagaagct tatgatatcg tcttgaacgg ttatgaacta ggcggaggtt ctatccgtat
    30781 tcatactcgt gagcttcaag aaaaagtact agaaactcta ggctttacaa aagaacaaat
    30841 ggaagaacaa tttggtttct tgttaacagc tttagattac ggattccctc cacatggcgg
    30901 tattgcatta ggattggacc gttttgcaat gttattagcc ggagaagata atattcgtga
    30961 agtcattgcc tttcctaaaa acggaaaagc agcagatgtg atgagtgatg caccaagtat
    31021 ggtttcgcct ttacaattgt tcgaattgaa tattgatgta acgaatatag aagaatagcc
    31081 gataaaaagg taaaaaggat ttgtcgaata cgcttctttt gacaaccttg atttaattga
    31141 aaaacacttt ataatgaagc cataacatat aaagcggggc ttttccatga aaaaaacatt
    31201 cgaaaattgg gcttatcatg attacacgac caagctttcg gtatctatcg tttatgcgtt
    31261 gatcgcatca gtcgcattga atttctttta tcagccagga catatttatt caagtggtat
    31321 tactggtcta gctcagattt tgacgacttt gtcaaaatca ctgataggat tcgaagtacc
    31381 ggtatcaaca actttgtatt tactgaatat acctttgttt gtattggcgt ggttaaaaat
    31441 cgggaagaag tttacaattt tcacttttat cacagtcact ttgacctccc tttgtatcca
    31501 tattttaccg gaaacagtcc tatctaccga tccaatcatc tgtgcgttgt ttgggggggc
    31561 tgtgatggga ctaggtattg ggctagcgtt gagaaacggc ctatcatcgg gcggtctaga
    31621 tatcgtgagt atcacgattc gtaaaaaaac aggaaagtcg attggttcta tttcgatcta
    31681 cttcaatgca ttgatcgttt ttgttgccgg aattctattt ggctggcaat atatgtttta
    31741 cagtacgttg tctattttcg tcagtggaaa agtaactgat gtcgtttata ctaaacaaaa
    31801 gaagatgcag gtaatgatcg taacgaaaca tccagaaaaa gtagtaaatg aaatccaaaa
    31861 ctgtatgcgt agagggatca cgatcatcaa tgaagcagaa ggtgcttata agcatgataa
    31921 gcagacagta ttgatgacga tcgttacacg atacgaactg cctctactta gagaagcaat
    31981 gaaagcttct gatccacaag cttttgtaag tattgcagaa aacgtccaga tacttggtcg
    32041 tttctatgag gatggcattt agatcgagtt tgacaaaaat tcatgaaata ctgctgtaga
    32101 cagacgttcg tttgtctgca gtttttttct accatagtag aatcagcaaa gaaaaactgc
    32161 ttttttattt gaaattttct taaagttgaa aaaaagcatg tttatttttt taaatttatg
    32221 ggatgataga aaaaaatagt agagaaagga cacgattcta cttgctattt tcacttaata
    32281 cccgtatatt acgaatgaaa aaagtttatg aaaagttgga atattgaatg gaaaaacaaa
    32341 aaaggttaaa aaacagccgc tacatcactg ggtttgatgg gctccgttca ttagctgtgg
    32401 tgggtgttat cttctatcac cttctgccaa ctagtatgaa aggcggctat ttgggcgttc
    32461 cgattttttt cgtcgtatct ggttatttga tcacggatct gctgcggcag gaatgggaac
    32521 aaaatggaaa aatcaatatt tggcaatttt atgtcagaag aatgaagaga ctctatccgg
    32581 cacttgtttt tatgcttgtg acagcttcgg cttatatcac tttgtttcag cgagggctgt
    32641 taaacaatct tcgaggagtt gtggtcagca gcttactgta tgtcaacaac tggtggcaaa
    32701 tcaataacgg tttatcttat ttcgatcgat ttgctaatga gtcaccgttt acgcatatct
    32761 ggtctttagc agtagaaggt caaaactatt tggtttggcc gatcttgttt gtattgttga
    32821 tggtatttgt tcgtaaaaga aaatggatct tttatactgt gttaggtaca tccttcctct
    32881 ccgccatctt gatgatgatc ttgtatacac caggaggcga tccaacccgt gtttattacg
    32941 gtaccgacac tcgtctgttt tctatatggt tgggaagtgc gcttgcgttt gtttggccaa
    33001 gtacgcgttt aaagaaaaac atcccgaaac aagcgaaaaa tattctgaat atcgctggag
    33061 gaatctcgct tttggcactg attctttgct tcttcttttt agatgatcat tacaatttca
    33121 tctattacgg aggaatgctc ctagtgagtc tgttatgcgt agtgctagtt gcagtgacag
    33181 cacaccccgg agcaagtttg aatcgatggc tgacaaatcc agtatttact tggattggca
    33241 aacgaagcta tggcatttat ctgtatcagt ttccagttat gattttttat gaagcaaagg
    33301 tgactgatat tgccgatcat gttttgttgc atactttagt ggaaatcaca ttgattctaa
    33361 tcatcagtga actttcttat cgatatgtgg agcgtccgct agcacgtttt gattatggtc
    33421 gtacattcca agtgatgaaa ggatggttca gcaaaccgat catcagtaag agcaaaccat
    33481 gggttgttcc aggcacatta cttgtagcaa ttgcactcgt tggtttcgtt acggcaccga
    33541 aaaacgctgt aacagccgat caaaaacaac tgcaggcaaa aatcgctgaa agtaaaaaat
    33601 tagcagaaga aaccagaaac aattcagaaa acaccactag ttcggttgac caagcgatcc
    33661 ttgataagta cgagttgtcc aaggcacaag ggaataaggc acaaaaatta gaactaacgg
    33721 catttggtga ttcagttatg ttggatgctg caacggatct acaagaactt tatccaaaag
    33781 tagtggtaga tggagatgtc ggacgacaat tatatgccag tgtaccgtac attgaaaaat
    33841 taaaggaaca agatttgttg aaagacactg ttctgatcgg actaggaacg aatggctcat
    33901 tctcggaagc tcagtttgat agtgtgatgg atgcaatcgg tgatcgaaaa gtatactggg
    33961 tcaatgtccg agtaccgacg aagcgctggc aaaatgacgt gaatgcgatg cttgaacaga
    34021 tgacgaaaaa atacgacaat atgacgctga ttgattggta cagctacagt aatgaccata
    34081 gtgactggtt ttatgatgat caagtccatc caaatcctga agggatgaca cattacattc
    34141 acttagtcag cgaagccttg ctaggaggaa gttcaagtac gaacagcagt gagacaaacg
    34201 tgacagaatg atagctacaa aaaacttcag gcaaaaacat ttgtttttgc ctgaagtttt
    34261 tttatattta ccgtgttttt aacattcata tagattcagg aagcaaaacg gttgagtgtg
    34321 tctgtaaata acgttctttt tgttttcggg tgagtttttt gaatgcagct tctgcttttg
    34381 ttgcttcgct tcttgaagaa aatacttctg catggatcat cttaacaggt cttctttttt
    34441 gaagacgagt atatttagca ccagtaccat tgttatgttc ctctaatcgt ctagaaagat
    34501 cggttgtata tccaccataa aatgtctgat ctttacagaa taatacgtaa aaataatgtt
    34561 catttgccat agagcatctc acgaatctct gcagtgtatt ctccatccat attgtaagtg
    34621 atcaatggtg gagcgacttt gaatccgtct aatttgcctt ctttgattcc ttcaactaac
    34681 aaaatatttg cctcttttcc aggttttggg taaacaaatt ggatcctttt aggtgcaatt
    34741 cgatagtctt ccatgacctg aatgatttct aagaaccgat caggacgatg gaccatagta
    34801 aagcgtccat ttgtttttag tagcttactt gaaatatcga tcacttcttc taacgtcgta
    34861 tgaatctcat gacgggcgat tgccaggtgt ttattagggt tcgttttatt tgttggcagc
    34921 cctttgaaat aaggtggatt acagacgact aagtcacaag aattatgtcg aacgacagat
    34981 aagctgtctt tcagatcgat ggtgtggaca gtcatttgtt catttaaatg gttaagcgcg
    35041 atactacgtc ttgccatgtc tgctagacga ggttgaagtt cgatagcgtc gatagccgcc
    35101 tgggttcgtt tacttaaaaa aagtccaact gcgccatttc ctgcacaaag gtcaacaatc
    35161 ttcccttttt taggtacacg ggaaaagtga gcaagcagca cagcatctaa agaaaaagaa
    35221 aacactttgg aactttggat aatcttgata tcttctgcgt ataattggtc gattcgttcg
    35281 tcttcgtgaa gcatggattc cctccaaaat gaaaaaaata gtcgtctgta ttatactatt
    35341 tttattaaaa agaaccaagg tggcttgtca aacctctatt ttttatgcat actatgacca
    35401 taagaaggga aaggaagaga ctatgtttta tcgatttatg cgcggggtag ttcgagtact
    35461 attagcctta gttaatggaa atgcccgcta tgagaataaa gaagttttac cgcaagatga
    35521 gaattacata ctagttgctc cccatcgtac ttggtgggac ccattatatc tggcggtagc
    35581 tgcagcaccc aaggaattca gctttatggc aaaagaagaa ctgttcaaaa atccagttct
    35641 gcgatttata ttaactcgat ccaatgcttt tccagttaaa agagaaaatc caggaccaag
    35701 cgtcattaaa acacctgtaa agattttgaa atcgacaaat ttgagtttga tcatgtttcc
    35761 cagtgggaca agacatgcta cagaacttaa aggcggaatg gcattgattt ccagaatgtc
    35821 taaagcgaaa atcgtgccag ctgtatatca aggtccgttg acacttgggg atctgttcaa
    35881 gcgtcagaga gtgacagtgc gtttcggcga accaatcgac ttatcagata tcaagaaaac
    35941 ggataaagaa ggtatggcgg agatcgaacg acgaacacaa gcagcttttg acaaattgga
    36001 caaagaagtg aaccctgatt tcaaatatga agtcaaaaaa aaataaaatg ataagtttat
    36061 gcgtgggcgg tcttttgaat ctactgtcct gttcagttca gactttttca atgaaaacga
    36121 gggagagacg tcaagtctgc cctctttttg cgttccaata tgtaaaatag aagacaggtg
    36181 tcatgtaatg gatcaaagtg ttataataat tagaaggaca ttttttgagg tgattgaatg
    36241 cgttttttac atacagccga ttggcatatc ggaaaaaaac tacaaggtta tgacttgatt
    36301 gaagaccagc gtcatgtact atcttctata ctagatatcg cgaaagaaga aaaagtagag
    36361 gcaatcgtga ttgccggaga cttatatgat aggagtgtcc cagctgttga tgccgtagaa
    36421 ttatacaatg aattgatggt cgattggaat ttaaaggaaa agatcccgat ttttgctata
    36481 tcaggaaatc acgatagcag tacgagactt tcagcgggta cgccatggtt cagttattcg
    36541 aactattttt tgcgaacaca gctagcagaa gcatttgaac cagtcgagtt taaaaacgta
    36601 caatttttct ttcttcctta ctttgaacca attgcagcga gattatattt tgaagatgac
    36661 aatatccgaa cgatcaagca agcggtagcc aaggtgatag ataaaatgca ggagctattt
    36721 gattcagaaa aaaaacaagt attgattagc catttttttg taatgggaag tgtaaaatct
    36781 gattcggaaa cgaaaatcga agtaggcggg ttggattcga tccctggtga actacttaca
    36841 ccgtttgatt atgtagcact aggacatttg cataatcaag ctgctttgag acaggataat
    36901 gctcgctata gcggttcccc attgaaattc tctttatctg agatcaacca aaaaaaaggc
    36961 gtatggatcg ttgacctgac aacaggcctg gagttgaatt ttagggagat cgaacccctg
    37021 catgatattg aagaaataac agcgagtttc aaagaattgc tggatcctgc cttttatcag
    37081 tccgtcaatc gggagaatta catctatatc tatctcactg atagaacgat catcccgaat
    37141 atgatgaacc agcttcggca aatatatcct cgtattttgg ggattgaacg ggcaaacggt
    37201 cgagcagaac aaacaaagcg caaacgaaaa gtactagaaa tgaaagatcc tcaaaaatta
    37261 gcagaagcat tttttagtga aatgacggaa gagcagctaa ctgcaaacca agaaaaatgg
    37321 ctcggagaaa cgttgcaaga aatcatggaa atggaatgat caagaatgaa accgaaaaaa
    37381 ttacaactta aaaattttgg tccttttatc aatgagaccg tagatttttc acgtttgaca
    37441 gaagcaccgc tttttttgat cagcgggaag acaggagctg gcaaaacgac gatttttgat
    37501 gggatcacct tcgcactttt tggtgaaact tccggaagac ttcgctctgg aaaagagatg
    37561 cgttctttgt ttgctacacc agacgaagaa acaagcgtga ctttttcttt tgaacatcag
    37621 cagatgagct atgaaatcga acgaaaacca gaacaagttt tagcaaaacg aaaaggaaac
    37681 ggaacaaaaa aacaggcagc caaagtaacg ttgaccattt ttgatgggaa aggaaaagaa
    37741 ataaaacaaa tcacaaaacg tacagaagca gatcagttga tcagagaact gatgaatctc
    37801 gatgcgaaac agttttctca aatcgtttta ctaccccaag gagaattccg taattttttg
    37861 gtttcatcaa gcagtgataa agagactgtt ttacgtcatt tattcggtac tcaatttttc
    37921 caacagttca atgagcgatt aaaagaaaaa gcaaaacaac agcaacaaaa attggatcat
    37981 ttagagcaag agctgcatct tctgcaaaaa aggtttgttt tagtcaaaga agaggaacca
    38041 gcagcagggt ttgaagccgt tttagcccaa tggacaaacc atcaggcaat actcgaaaaa
    38101 caaatcacgg aagaaaaaga agctctaacg gaacttcagg aaaaacaaaa gcaactagaa
    38161 aattcctact atcgttttga aagcttgaaa aaaagttatg aagaaaaaac gatattaata
    38221 aacaagcaaa aggaattagc tgctcaaaaa gacgaaatag aggaaaagaa acgatggatt
    38281 gggtattatg aatttacgca acgattagtc gaaccaatcc agcgcctaca agaaataaaa
    38341 gttgaaaaaa tagaactgtc acaaaaaagt agtgagcaaa caaagaaact agcgatgact
    38401 acgcagaatt atgaagagtg gcaaaaaaat gaagcaaacc gcgtacgccg acaaacaaaa
    38461 atcaaagaag ctgctcaaaa actgcaaaac aaacagatga tggtgccaat tgtcgaatcc
    38521 ttacgtagta aaaaacaaga cgcagaacaa ttaacaattt cattggataa agaagaattg
    38581 aatgccgaga agctgtatca aaatctcgct atctatcagg aaagaactcg aattcttcaa
    38641 gaaaatttac tggatcagga aaaactgcaa gaagatcgtc ttgcttttgg acagttaaaa
    38701 tatctagatg aaaagcagca agaaatagaa aaacaaaaag caaaagacac tgggtcgctc
    38761 gcacagataa gagaagaact caaaaaagca actgaagaaa taacaaaaaa tagtcagcta
    38821 ttgaaagaac agacagaaca agcagaacag ctgaaaagcc aatgggcaaa gcagcaaatt
    38881 gctcgtcttc agcttttttt gcgtccaggg gagccatgtc ttgtttgtgg atcaacggaa
    38941 caccccatac aacaattaaa acacgaacag ccaaataagg aagatatctt aaaagtagaa
    39001 caacaactgg cagaagctga gtctgctgta gaaagaactc agcaaatcat tgccaaaagt
    39061 gaagcacatg aaaataatct tcaacaacaa ttatcagatt tagaacaaaa aatcatggca
    39121 acgaatatac aattggctga acaagaagaa cacttgcaac aggctttgaa aaaggcattt
    39181 cctgagataa cagaacaaaa aacaaaaaca actcttgtag taatcgaaca atctttagat
    39241 agacgaaaaa gcaagatggc caatgcaaga atagagctgg aagaaataag acaacaagca
    39301 gaaaagctcg aacaacaatt agctgtctac aaacagcagc agacagaaaa aaataatcag
    39361 ctccagcaac tgcaaggaga aatcaaaagt ttagaacaac aattgcaaga tacggatagt
    39421 aactgtttag aagaggagat acgacgactt gaaaaacagt tagaagaaga ctcgaatcaa
    39481 ctagctgttg agcagaaagc aggagtgcaa ttgttgcaag atcttcatac gcttcggaca
    39541 cagcttgatc ttcaacatga acaaatagaa aaaatagatg aaaaaataga aaaggaacaa
    39601 gaaagaatag ctaaaaagtt agaaagccag tcgtattttt caacaattga agaaatctgt
    39661 gcatttgcac aacagcaagc acaatataaa gaaaaccaac gtacagttac ttcttatcat
    39721 gaagagcaat tagtgacagc tgaccggctg cgtcaattag aaaatatcca gctaactgag
    39781 acattcccag atacagaaga gatcagccaa cagttagaag aaataagacg tatgatcgaa
    39841 ataaagcaag aaaagatata cggtttacaa gaacaaaaaa ttagtaatca aaaaatctac
    39901 gatgaatgtc tttcgattta tcacacaagc cagacgaaat tagatgagct tacgcaatta
    39961 cagcagcttt cgcaaacatt caacggagaa aatcctaaga agactagttt ggaacggtat
    40021 gtgcttcagg tttatcttca agaagtgtta caagtagcaa atgatcatct ccaacgttta
    40081 acgaaaaatc gttatcaatt tgagctagcg gataccattg gcagttatcg agggaaaacc
    40141 ggattagaaa tcaatatcta tgatgatcag gcaggtatgt ctcgaagtgc gcataccctg
    40201 tctggcggtg agagttttat tgcagcactt tctttagcat tagctcttgc cgatgtgatc
    40261 cagacacaag ctggtggtgt agcaatcgat gcattgttta ttgatgaagg atttgggtca
    40321 ttagatgaag aagctttgga aatggcaatg gaagctttag aaacgatcga aagtgaagga
    40381 agaatgatcg gcatcattag tcatgtaaga gaattgaaag aacgagtatt acaacaaata
    40441 agaattgata cagaaggtag cggacaaagc aaaatacgct atcaacttgg ataaaaaggg
    40501 agattggtaa ctatgaaatg gagtattcca gaaaaagtca ttgcacgtgg acgtcaatac
    40561 ttgcaagaag gccgagtgtt atcggttgtc cctgaccaag aagaaaacgt gtggcatgca
    40621 gaagtcttgg gcagtgaatt gtatatggtt gatttggatg gtacagcaaa agagatagat
    40681 tactgccaat gtccctattg ggaggaacat aaatattgta agcatacagt tgctgtggaa
    40741 ctttatttac ggtcgaaaaa tctatctcgt atcatgaaaa aagaccagcc aatgctagaa
    40801 ccggtaaaag caacaagtga gggagaaatc attgcaaaag gtttttctcg tctaaaaaca
    40861 caaaacaatc ctcaagcggt gcaacctttg attattgaat accaagtaga aacgattgag
    40921 actaatcagt atcacccaga gctttctatt ttggcacttt acttgcgtat cggttcattg
    40981 gcatcaccga aaaaaacata tatcgtaaaa aacatctatg attttttaca agcttacaca
    41041 gaaaaagaaa cttacactgt taataaacag taccagtttc gtctagataa acgggcgttt
    41101 caaaaagaag atcaaaaaat actcacgcat cttgcaggaa gtgctcagac gcatcaatta
    41161 ttaggtacga acggcttaca agtcaaagga aaactagata aaagatatct gcttctccca
    41221 gtagaacaag cccgcttcct gttagagcag atgaatcaga ctacacgttt gcatctgcag
    41281 ataaatgaac aaaacgatca aggaatacaa ttttccgatc aaaacaaacc tttatcattc
    41341 aaagtggaaa aatttggaga agattatttg ctgcaagcat tgaatgattt tgattttttc
    41401 tttatgcatt atcagtgggg agttatccaa gggacatttt attctctgac gaaatatcaa
    41461 caaacggttt atcaaacttg gaaacaattg attcgccgat tggagaaacc agaagtagtg
    41521 ttcaagaaaa aagaattacc gtctttgttt aaagagatta tccctctgct gtcagagatc
    41581 ggcgacgtag ctattgcccc tgcagtagaa gaggaagtag cagatatccc cgtcgaattt
    41641 attttctttt tccgaaaagc aaaaggaaaa atccaagctc gagtcgattt cgtctatggc
    41701 gaagtcatct attcgactga cccgaagcat gaggtctcga cagaacaggc ttttcaggtg
    41761 ttacgtgaca cagtagaaga gaaacgagta cttgatctat tcagaatgta tcgctaccag
    41821 aaaaatgaaa ctggttatga acgtccattg ccaagcgggg aagaactata tgcctttttc
    41881 cgcacagaac tatctgtctt ccgtcagttt ggtgaagtca gacttggaag aaaattgcga
    41941 gagttgtatt tagatgcgca taaacatcaa ccgaaaatcg aagtaaccga gaccggttca
    42001 tggctcgata ttcgattcga tgtgacaggg atagaggagc aagaaatcga tcatgtcctg
    42061 caaagcttgc tgagaaatga tgctttttat acattagaaa atggtcaggt tctttctttt
    42121 gattcagaag aatttcaaca aacaagccaa gtgttgcaac aattacggga atcgatacgt
    42181 acagaagaag gaacgatcca tgtacctaaa aatcaaggat tgatcattca aaatcaattg
    42241 gaaaaaagca atgctacttt tagtgaatcg ttccaaacga tggtacaaga tctcattcat
    42301 ccagaaagat accaggcaca gcttcccaaa ggattgaatg caacgatgag agattatcaa
    42361 aagcaaggtt ttcgatggtt gaagatgtta ggtcattatc agtttggcgg tattttagcc
    42421 gatgaaatgg gacttgggaa aacactacag acaattgcct ttttactttc ggaaaaagaa
    42481 gaacggaaaa gcttctctgc tttgatcgta gcgcctgcga gcttaattta caactggcag
    42541 gcagaggtga gaaaattcgc cccttcttta agtatccaag taatcaatgg gaataaaaaa
    42601 gaacgtgaag aattactggc taaagacaca gatatccgag tgacttctta tgccagctta
    42661 agacaggatc tagctaatta tcagtcgcaa aaaattgatt atttgattct tgatgaggca
    42721 caaatggtca aaaatagcag tacgaaaact gcacaagcat tgagagaatt agctgtacct
    42781 cagcggtttg cactgagtgg gacaccaatc gagaataatt tagaagaatt gtggtcattg
    42841 tttgcaacga ttatgccagg atttttcccg actaaaacaa aattcaggga acttgccgca
    42901 gaagaaattg cgcaaatgat tcgaccgttt attttacggc gagataaaca aactgtgttg
    42961 aaagacttgc cggaaaaaac agagatgaat ctatattctg cacttacaga agaacaaaaa
    43021 actgtttatt tagcttactt gcgtcaaatg cgtgaagaaa tcacatcaat ggattctgaa
    43081 gcattcaaga aaaaccggat cgggatactt gctggtctga caagactgcg acaaatttgc
    43141 tgcgatcctc gtctgtttat tgaagattac caaggcggtt ccggcaagct cgaacaagta
    43201 aaagatctac tggtagctgc caaagagaac aaacgaagag ttttgctgtt ttctcaattt
    43261 acagggatgc tgactatctt gcaagaagag ttagccgagc tagggatctc gacattttat
    43321 ttaagaggca gtacgaaacc acaagatcgg ttaagtatgg tagacgcatt taatgctggc
    43381 gaaaaagatg tttttctgat ttccttaaag gctgggggaa ctggattgaa tctcacggga
    43441 gcagatacgg tcatcttgta tgacctttgg tggaatcctg ccattgaaga acaagctgct
    43501 ggacgtgcac atcggatcgg acaaaaaaat gtggtagaag tgtggcgtat gatctctgaa
    43561 ggaacgattg aggaacgcat ggattcactc cagcaagaaa aacgcgaact gttccaaaaa
    43621 gtgatccaag gtaatgaaga acagttgacg aaactgactg aagaagacat ccgcatgatt
    43681 ttaagtgtag gagaaatcga ggagtaagag actcgaaaaa gcgttcagta atgggtaaga
    43741 aagcctttct aaagaagcga ttgtttattt gatttaaaaa atagcaagga ggctgggatt
    43801 ccattttatc ccagcttcct tgctatcatt tttttatttc tatttttaaa ggttatacaa
    43861 agattgtctt cattgtctct aacagctgat caaaagaaga aatctcgata tcgcaaattg
    43921 gagtctgttc aattttgcgt tctcgatggt tgaaccaaag cgcttgccag ttagcacttt
    43981 ttgcacctag aacatcattg tcgtaattat cgccaacgta taaggtctct tctggaagca
    44041 tatgaaattc tttctcagct agctgaaaaa tctctttttc tggtttttgg aaacctgttg
    44101 cttgagaaat gagcatattg cgggaaggaa tccaattgtt caattgaagt tgcttcagtt
    44161 tttttgtctg atggtcagtc ggcccatttg tgataattcc taatgggaca ttcttttcct
    44221 tcaagaaatc gagggttttt ttgacctcct catgcaagca gatattatca agttcttcct
    44281 cgtaaatttt ttgaaataag aggccatctt cttccgtaat atgagggtag tctaaatctt
    44341 ttagtgattg gctgatccga tgtgctcgca tatattctag tgtccaatct cctgccatta
    44401 cttttgggaa gttttcatca ctatgatggc ggaaccggat atatagtgga tgcatatctg
    44461 catctgaaac aagcggaacg actcttttga ccgcgtttcg aaatggctgc tgctgatcat
    44521 acatcgtatc atcaacatca aacacaactg atttaatcaa aattttacac gcctttcggt
    44581 tttcattgat tttttcacaa atccttgact attgtaacag aaaaaattgt ctaaaaaagc
    44641 tgataaataa aggtttttct tactatattt ctatttcctt gacagaataa ggtttttata
    44701 tttcagtttt tttcactaaa aatcgtgaaa cacgtcaata agtttgatga acaaattaat
    44761 cattatggta gaagtcgatt gatttatttt aatgcaatct ctgtggaatt ttcgaaagat
    44821 ttattttttt aatacagtct caatataact attcaaacat aaaataacgt tatttgattt
    44881 atttgtttat agtaaatttt atttagtaat cattgcttta aaatactacg cttatataac
    44941 agagaaaata agcgttataa taaagaacag tattatttaa aatgacagaa aacattacta
    45001 ttaaagaaat aaaaaacata aaaaatctta agaaatcggt ttcatttagc ttttgagata
    45061 aaataatagt acagttttat acgctgtttc atatgtttag aaaatttgaa ttagatttga
    45121 aaactctaat ttttaaatga taaaaaaagc gagaatgctg gttttactgt atattaacct
    45181 tagataactt tcattttttt aaaaaaatta tgaaaaaaag gtagctattt aaaagttgat
    45241 tatgtataat agaaacagat gggagattat tatgatcttc tgttacaaaa aagtgattct
    45301 tatcacgaaa aggagtggtg cacgttgtta acattatata cttccccaag ttgtacttcc
    45361 tgcagaaagg ctcgtgcgtg gttgcaagaa catcagattc catttgttga acgtaatatt
    45421 ttttcagaac cattgaacag ttctgaatta aaagcgattt tacaaatgac agaagacgga
    45481 acagaagaaa tcatctcgac acgttccaaa gtattccaaa aactgaacat ggatttagat
    45541 gatctgccgt tacaagaatt attggaactt gtgcaaaaca atcctggatt gcttcgccgt
    45601 ccaatcatga ttgatgataa acgtctgcaa gttggtttta atgaagatga aattcgtcgg
    45661 ttcctaccgc gcgatgtacg acaattagaa ttacgtcaag cacaattgat ggctggatta
    45721 tagaaggata atacgaaact tggaaaagac tattacaaag atagtttttc caagtttttt
    45781 tgtttttaca aaaagtattc ttgattagat gtataaaaag gtagtagaag atgatgattg
    45841 cacgaaaaat agagagggaa aattagctga aaagtcggct atatagtatt cgtctgccaa
    45901 aaatgttata gttaaataag atagcttgaa aggttgaaaa atccgctggt tttattaaat
    45961 tcgcttaaca gcgagatttt ttttctttac atttaagctg atttcgctac aatgaatcta
    46021 tattaaacat tgtggcaaag tgaggtgtag caaaatggaa atggaacata ttaatgaaaa
    46081 tacgatccgt gtactaattg gtcatgaaga tttagaggaa cggggcgttt catttttgga
    46141 tttacttggc aatcacaaag aaatcgaaaa tttcttttat agtattttgg aagaagttga
    46201 tatcgaagag gagttccgag gaagcgaagc tgtcactttc caagttttgc caaaaggaga
    46261 cggattagaa ctgtttatca gtaaaaatct tccggatgaa gaaatttctc aatcagaaga
    46321 ttctactgtt gattcagaag atgtgagtga ctttcttcgt cagcagatta ttggcagcga
    46381 tccggaggaa gaattatctg gaagcgccct agaagaacag gaaagacaag caacttttgc
    46441 ttttgaagat tttgaacaag tgatccaact tgcaacagat gtcgaactag agtctgcttg
    46501 gactgatttg tatttattcg aagagcgcta ttacctagtc gttcacttct ggatggaaaa
    46561 tctcaaccaa gcggatgtag agaatcagat tgctcgaatt ttggagtttg ctgaaaagag
    46621 cgatcgtaca ccagaaacat tgaatgaata tggacaatgt ctgatggcgc gtaatgctat
    46681 cgagcgaacg aaattttatt ttgtataaat cagcattata gtaagagact gtgacaaaaa
    46741 ttgtgtcgca gtcttttttt cgtataaatg tgttcaaaag cttgcatctg cggtaacaag
    46801 cccaaccaaa cgaaaaatat tgggaactat ttttgtttag ctgttcttat tacttgatgc
    46861 agaatagctt tttcacgccc tcttttttcg tgtaaataaa ttcttagacg taaataagtt
    46921 cagagggaga aaaatgctgc ttgcaatgaa tgaatataat aagtgctgtt ttgctaaaca
    46981 tgcagaaaaa ggaaagaaat attattgtcg tggctgtcga aaaagagtga ttttgaaaaa
    47041 gggaaagaaa aaatgtgctc attttgccca tcaaaaatca gataactgtt cggtctttag
    47101 tgaaagagaa tcaaaagagc acttacagtt aaaggaatgc ttcatggatt ggctgggaca
    47161 gtcagtagaa ccagtatttt tggaagccta tttgccgagg ttgcggcaaa ggccggatat
    47221 tttgttggcg aatctagcaa tagaaatcca atgttctaga ctgtctcacc agagatttat
    47281 tgaaagaacc caaaattatt tgaataacag ttaccaagta tggtggatac ttggtaattc
    47341 ttttcttgga caatcgcaat tctcattgat agaaaaaagt tgctgctact ataatagaaa
    47401 aagaggagtg cattgctgga aagctgatct caagaaacaa aagctttatt tgtatcatca
    47461 tattacagag actgtatcag ggcatatttc cttttgcagt agctgctgga ctttttctag
    47521 tagggacctt aaagaaatat tcactagtaa cgaaattaaa atgaaccaaa tgaaaaaaat
    47581 agaaaaagtg agtgaagatg ggaagaaatg gctgacacgc caacttattc acaagcaaaa
    47641 gaatacagta tccatacaag aacaatgcta cttgcgtcat aaacatcttt tgcatctatc
    47701 atcgtggatc tatcaaaaaa gtcggttttt cttttattta caagaacagg tttttcttta
    47761 tcgaatgttg tacgaagaag ccttggaaaa ccagaaagtt cctgatttca actcatggct
    47821 ttgccaaata aaagaacata aaagggaatg gctttttcct atgattgatg aagagatggt
    47881 ctatcagcag ttttttaacg aatgcataca cttgtcttct ttgaaaaaat agtaagtata
    47941 aaaataggct aggaatcggt tttctatgta aaacaagatt tagttatgct aaaattgatg
    48001 gaagcagaca catgaatgag tagaaaagtt agatgctgtg acatgtggat gttagactat
    48061 gatctatttt gatagataga gctaagggaa gaaaaggagt ggatttcatg gaagtaaagc
    48121 agttgccaaa acgagaagaa ttgcctgaaa atttaacttg ggacttgacc aagatctttt
    48181 caagcgacca agagtttgat gagaaatatt tggaattatc agaagagtta aaacaatctg
    48241 aaaaacacaa aggaacactt gatcaaggcg cttctcaatt tttaaatgcg attgaattcg
    48301 tattgagggt ttatcgccaa actgaagtca tttatgtata tgcgcacctt aaaaacgatc
    48361 aagacactgg aaatacagat taccaagcgc tttatgcaag agcaagcagt ctgttttcga
    48421 aagttagtga agccgtttcc tggtttgaac cagaaatatt gcaattgtca gatgaccaga
    48481 tttggcaata tttcaaagaa gaaccaaaat tggaagtcta tcgccattat atccagcaaa
    48541 tagtagataa tcgagcccat gtcttatctg ctgagcagga atctcttctt gctggagcag
    48601 gtgaaatctt tgatgcttca agtgatacat ttgctgtttt gaataatgca gatctagttt
    48661 ttccaacgat tgaaggagaa aatggtgaaa tagtccaatt atctcatggc gtgtatggtc
    48721 agttgctaga aagcacggat cgaagggtgc gcgaagcagc atttaagggg ttgtacagtg
    48781 tttacgaaca atttagaaat acatttgctt ctactttagg cacacatata aaaggacata
    48841 attttaaagc gaaagtccgt aattacagct ctgccagaga agcgtctttg agcaataatc
    48901 atattcctga aagtgtatac gatactttgg tagacgtggt aaacaagcat ttgcctttgt
    48961 tacatcgata catggaatta cggaaacgtt tattagaagt ggaaaaactg cacatgtatg
    49021 atctttatac accggtctta ggggaagctc caattacctt tacgtacgaa gaagcaaaag
    49081 aaaaagcttt agaagcactg aaaccaatgg gtgaagaata catggccatc gtagaaaaag
    49141 cattctctga acgttggatc gatgttgtcg aaaataaagg gaaacgaagc ggtgcttatt
    49201 cttcgggaag ctatgacaca aatccatata ttttattgaa ttggcatgat acgctggatc
    49261 agctatttac gcttgtccac gaaatgggac atagtgttca tagttatttc actcgttcga
    49321 accagcctta tgtgtacggc gactactcca tctttttagc agaaattgct tcgacaacga
    49381 atgaaaatat cctaacggag tatttattgg aaacagaaaa agaccctcgt gtacgggctt
    49441 atgtactcaa ccattacttg gatgggttta aaggaacagt tttccgccag acacaattcg
    49501 ctgaattcga gcatttcatg catacggaag atgaaaaagg tgtgccattg actagtgaat
    49561 acctaagtga tagttatggt aaattgaatg caaaatatta tggtccagca gtcgaagaag
    49621 acccagaaat taaattcgaa tggtcacgga taccgcattt ttattataat tactatgttt
    49681 tccaatactc gactggcttt tctgctgctt cagcactggc gaagaaaata ctaaaccagg
    49741 aaccagaggc actagagaac tacttggctt acctaaaagc aggtaacagc gattatcctg
    49801 tggaagtaat gaaaaaagca ggagttgata tgacacaggc tgcatatatt gaagatgcaa
    49861 tgtcgatgtt tgaacaacgt ctaaatgaat tagaagaatt gatcgatcgt ttataaggct
    49921 ttctattttt gattttctcg aatagaaacg aaaaaaatac gtcggctctc ttgtaaggga
    49981 gtcgacgtat tttttt
//
LOCUS       DAFENC010000018        48823 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.018, whole genome shotgun sequence.
ACCESSION   DAFENC010000018
VERSION     DAFENC010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 48823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48823
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.018"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            23..646
                     /locus_tag="LP493_001338"
     CDS             23..646
                     /locus_tag="LP493_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133497.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1096..2145
                     /locus_tag="LP493_001339"
     CDS             1096..2145
                     /locus_tag="LP493_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL2133498.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2142..3023
                     /locus_tag="LP493_001340"
     CDS             2142..3023
                     /locus_tag="LP493_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2133499.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3026..3796
                     /locus_tag="LP493_001341"
     CDS             3026..3796
                     /locus_tag="LP493_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2133500.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4075..4929
                     /gene="aroE"
                     /locus_tag="LP493_001342"
     CDS             4075..4929
                     /gene="aroE"
                     /locus_tag="LP493_001342"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBL2133501.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5107..6270
                     /locus_tag="LP493_001343"
     CDS             5107..6270
                     /locus_tag="LP493_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBL2133502.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6387..6797
                     /locus_tag="LP493_001344"
     CDS             6387..6797
                     /locus_tag="LP493_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL2133503.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6971..9199
                     /gene="topB"
                     /locus_tag="LP493_001345"
     CDS             6971..9199
                     /gene="topB"
                     /locus_tag="LP493_001345"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBL2133504.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9370..9654
                     /locus_tag="LP493_001346"
     CDS             9370..9654
                     /locus_tag="LP493_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133505.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9814..10050
                     /locus_tag="LP493_001347"
     CDS             9814..10050
                     /locus_tag="LP493_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL2133506.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10047..10445
                     /locus_tag="LP493_001348"
     CDS             10047..10445
                     /locus_tag="LP493_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HBL2133507.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(11112..12056)
                     /locus_tag="LP493_001349"
     CDS             complement(11112..12056)
                     /locus_tag="LP493_001349"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBL2133508.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(12352..13296)
                     /locus_tag="LP493_001350"
     CDS             complement(12352..13296)
                     /locus_tag="LP493_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2133509.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            13517..14731
                     /locus_tag="LP493_001351"
     CDS             13517..14731
                     /locus_tag="LP493_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2133510.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            14753..16768
                     /locus_tag="LP493_001352"
     CDS             14753..16768
                     /locus_tag="LP493_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HBL2133511.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(16851..18224)
                     /locus_tag="LP493_001353"
     CDS             complement(16851..18224)
                     /locus_tag="LP493_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBL2133512.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(18250..18534)
                     /locus_tag="LP493_001354"
     CDS             complement(18250..18534)
                     /locus_tag="LP493_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2133513.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(18536..20551)
                     /locus_tag="LP493_001355"
     CDS             complement(18536..20551)
                     /locus_tag="LP493_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBL2133514.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(20730..21035)
                     /locus_tag="LP493_001356"
     CDS             complement(20730..21035)
                     /locus_tag="LP493_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HBL2133515.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(21124..22155)
                     /locus_tag="LP493_001357"
     CDS             complement(21124..22155)
                     /locus_tag="LP493_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL2133516.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            22362..23237
                     /locus_tag="LP493_001358"
     CDS             22362..23237
                     /locus_tag="LP493_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL2133517.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(23389..24231)
                     /locus_tag="LP493_001359"
     CDS             complement(23389..24231)
                     /locus_tag="LP493_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL2133518.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(24323..26200)
                     /locus_tag="LP493_001360"
     CDS             complement(24323..26200)
                     /locus_tag="LP493_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBL2133519.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(26197..27618)
                     /locus_tag="LP493_001361"
     CDS             complement(26197..27618)
                     /locus_tag="LP493_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBL2133520.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYRMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(27621..31010)
                     /locus_tag="LP493_001362"
     CDS             complement(27621..31010)
                     /locus_tag="LP493_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBL2133521.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            31267..32658
                     /locus_tag="LP493_001363"
     CDS             31267..32658
                     /locus_tag="LP493_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2133522.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(32731..33378)
                     /locus_tag="LP493_001364"
     CDS             complement(32731..33378)
                     /locus_tag="LP493_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBL2133523.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(33386..34072)
                     /locus_tag="LP493_001365"
     CDS             complement(33386..34072)
                     /locus_tag="LP493_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2133524.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(34078..35151)
                     /locus_tag="LP493_001366"
     CDS             complement(34078..35151)
                     /locus_tag="LP493_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2133525.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            35373..36047
                     /locus_tag="LP493_001367"
     CDS             35373..36047
                     /locus_tag="LP493_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2133526.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            36052..37392
                     /locus_tag="LP493_001368"
     CDS             36052..37392
                     /locus_tag="LP493_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL2133527.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(37541..38527)
                     /locus_tag="LP493_001369"
     CDS             complement(37541..38527)
                     /locus_tag="LP493_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HBL2133528.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            39251..40282
                     /locus_tag="LP493_001370"
     CDS             39251..40282
                     /locus_tag="LP493_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL2133529.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            40391..41923
                     /locus_tag="LP493_001371"
     CDS             40391..41923
                     /locus_tag="LP493_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HBL2133530.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIPILYLMEQPALSVSQSFLD
                     KNEISYMTHTSGTTGIPKLICHSAHSMGWRTKWQKTVFTKISEKKLIAFHISPVHSRF
                     NIGISSLMSMGFPMMPLANAQSSKVVHMLEAHRPIALETHPNNFVQWRFTAKEHPEAF
                     SGIRYYHSTFDAINNQTMKTFLRTSMAQDAVFLQVYGQSECGPMILKAHTLESLKTSD
                     ARDMGVGLEDMTSARITDSVGNVLPENTDGHIQLLSKGRALTYYKEDARFQENVYGDW
                     WDSGDYGFMDKHGHLFLKDRQVDLIETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSP
                     QPIIALAPDKEMDWNRWWEQVHELPRLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQ
                     KS"
     gene            42062..42874
                     /locus_tag="LP493_001372"
     CDS             42062..42874
                     /locus_tag="LP493_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HBL2133531.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            42864..43349
                     /locus_tag="LP493_001373"
     CDS             42864..43349
                     /locus_tag="LP493_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBL2133532.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            43372..43917
                     /locus_tag="LP493_001374"
     CDS             43372..43917
                     /locus_tag="LP493_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HBL2133533.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(43990..45633)
                     /locus_tag="LP493_001375"
     CDS             complement(43990..45633)
                     /locus_tag="LP493_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBL2133534.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKHALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(45762..47990)
                     /locus_tag="LP493_001376"
     CDS             complement(45762..47990)
                     /locus_tag="LP493_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL2133535.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKERTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            complement(48023..48502)
                     /locus_tag="LP493_001377"
     CDS             complement(48023..48502)
                     /locus_tag="LP493_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133536.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNMDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
BASE COUNT        14861 a         8994 c         9181 g        15787 t
ORIGIN      
        1 aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat cgagagtaca
       61 agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt attttcgacg
      121 tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt tattgccgga
      181 aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa ccagcaaatt
      241 gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg cgatatcggt
      301 gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt ttaatgatcc
      361 tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt atgatgtaca
      421 tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt tctttgatgg
      481 aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt ttgataagga
      541 gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag aagaagaatt
      601 ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca ttggcgcgat
      661 gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg tttgatcttc
      721 aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt cgattagact
      781 taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt atttcagcag
      841 aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg agactttccc
      901 atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga catgaacatt
      961 gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga ccgctttggc
     1021 cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa agattgactt
     1081 tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat tattttagtt
     1141 tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag tacttcgacg
     1201 aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca tccggcatta
     1261 gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa agaaggagaa
     1321 aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc cacaatgagt
     1381 caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc tgccgctcaa
     1441 tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac ggatcctgtg
     1501 ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg tgtttctgat
     1561 cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa tgcaaaaaaa
     1621 gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc acaagcagaa
     1681 gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc cactaatgag
     1741 attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt tccattagat
     1801 aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc aaatatcccc
     1861 gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat cgggatcaat
     1921 caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag tggaaaagaa
     1981 aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat caatcaatct
     2041 caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc caaaatcatt
     2101 acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta tcagctattt
     2161 cacaaggcat gctttgggca atattaggat tagggatttt catgacttat cggatcttag
     2221 actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc tgtgtgacag
     2281 ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt gctggcatga
     2341 tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt attttagcag
     2401 ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga acaccaaatc
     2461 tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg ttacctgatt
     2521 actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct gtactgctat
     2581 tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac gaaacgatgg
     2641 ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact ttgtcgaacg
     2701 gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca gatgtaaata
     2761 aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa gtgatcttcc
     2821 aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc atttatcagc
     2881 tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag ttgttctccg
     2941 ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg aacttaaaaa
     3001 cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa atggcagaaa
     3061 agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta accttacaat
     3121 cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa gcacactgtt
     3181 caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta aagatcagct
     3241 gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt tccaagaccc
     3301 caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg cacaaaaaag
     3361 aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag attttttcag
     3421 actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag cgggtgaatt
     3481 atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag ctcctgagtt
     3541 actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag cattaatgcg
     3601 attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca cgcatcgaat
     3661 ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga aaatcgttca
     3721 agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc agttctttga
     3781 agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact tgaaaactca
     3841 ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa catatttggg
     3901 tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt ctttgctctg
     3961 acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc gtactttttc
     4021 gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa taagatgatt
     4081 tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag tttatcccca
     4141 ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt agctttccaa
     4201 gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga tatgttaggt
     4261 gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga ggtaagccag
     4321 gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg tttgattggc
     4381 tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat ttcgatcaaa
     4441 aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac tgttcaagct
     4501 gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac attcgctcaa
     4561 gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa agttcgtgac
     4621 tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct agtcaatgca
     4681 acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat aagcatgatg
     4741 catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg tttattaaaa
     4801 gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat ctaccaagga
     4861 gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat tgaaaagctg
     4921 tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg gtctcaagaa
     4981 aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat tatcaaaaaa
     5041 tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa acgaggagga
     5101 accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa acctctgaag
     5161 cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat ggaaaatgag
     5221 gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt gaaccaatac
     5281 gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa taaaaaattt
     5341 ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc gtggaaaaaa
     5401 atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt ttttattggt
     5461 aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac ctttcatggg
     5521 caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac acgcggagaa
     5581 gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc ccataagccg
     5641 aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg acaaaataag
     5701 atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt agtagaaaat
     5761 tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga aaaagtgatc
     5821 gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa tctggatggt
     5881 gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca gtacgcacgt
     5941 ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca agtaatgaac
     6001 gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta tgcagctggt
     6061 aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa aaacctcttt
     6121 tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga cggttcgtgg
     6181 aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca aatgaatcaa
     6241 tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag aagctgcgca
     6301 aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc ttatggtaga
     6361 tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa aatgagtcgc
     6421 gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt atcaccacat
     6481 acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa aatctaatca
     6541 cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg ccagaaggaa
     6601 ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca agaaatgaag
     6661 aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag atgccactgg
     6721 atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc atcaactggc
     6781 agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa gcagcaaacg
     6841 gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt atcttttttt
     6901 tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat taagtaacgg
     6961 aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa aagcctatgc
     7021 cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg atccattgtt
     7081 tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg ttgctccagg
     7141 agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt tcccagaaac
     7201 cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa aacgagaatt
     7261 gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg aagccatcgc
     7321 gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt tacgtttatg
     7381 gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc aacctggaaa
     7441 gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt ggctgattgg
     7501 aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg atggcagttt
     7561 ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc aagaagaaat
     7621 caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga caaacaaagg
     7681 gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag agttaacgaa
     7741 ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc ttgaagttac
     7801 gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt tgcagacaaa
     7861 gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc aaggattgta
     7921 cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag aaaatgagca
     7981 tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag aagaagtaca
     8041 gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc aagaacatca
     8101 tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc tttccaaatt
     8161 acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg ctgcagatta
     8221 tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa aaagcatcgg
     8281 aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa aaaagaaaga
     8341 agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac tgaaaagtat
     8401 ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca cagcaatgaa
     8461 aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag aagtagaagg
     8521 aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga agcattacat
     8581 cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt gtaaggcagt
     8641 agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag ggtacttgag
     8701 aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca aaaaattcat
     8761 cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt cagatgagat
     8821 tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag gaagatgtcc
     8881 aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct tgaatccgga
     8941 atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa cgaatctcag
     9001 agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg gtaaaaaagg
     9061 gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt cttttccatg
     9121 gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa gaaaaaataa
     9181 tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt ccgaaaagtg
     9241 agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa cgttggggta
     9301 ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca ttcattttta
     9361 aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct aaagtatcct
     9421 gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc accaacgttg
     9481 attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca taaaacgaca
     9541 agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc ggctatgatc
     9601 attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg ttaagaatac
     9661 gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt tcgtaagaaa
     9721 aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa tgtacttact
     9781 atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa gtataaaatt
     9841 agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga attcatgggt
     9901 gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt acgaatgatc
     9961 aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa tcaatatgaa
    10021 gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa attatcaaaa
    10081 tcaacgcgaa agttatttta cgtcactcgc caggcgaaat gatcggtgta aaagatgcaa
    10141 atgcattaga tatggccgtc aaacagcctt cacaagcagt attcaatcaa gaactctatc
    10201 ctgaaatcta tgaaaaagcg gcgattttag caattaattt agctaaaaaa catccttttc
    10261 ataatggcaa taaacgaact gctcttgttg ccatgttgtt gtttcttcaa ttgaataatt
    10321 gtccagttgc tttttctcgt caagaagctg ttgattttat cataatgatt accactagtt
    10381 cattggattt cgattcacta aagtccaaga taaccagtta tttacgacaa accgcaataa
    10441 aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc atgtcattaa ggaatatgct
    10501 gattttttta tgtttaatca tacaaaatag ttttttcata aaaatatgga aaatatggat
    10561 taattttgaa ataattgatt taaaaggaat acaaaagagt gaatagtagg aaatagtggt
    10621 ttagaactag tgggctgatt ttttatatat tttagtttac ataatatata ttatacaaag
    10681 tagatttaaa aaatgataaa cctctctcga acggtttttt atcaaaaatc gtcatttttc
    10741 catcaaaatc tgcttatgca aaattataaa aaaattttgc agtttttctt actttttttg
    10801 tcgtttaatt gaatgataaa aaccagtttc tttattcagt taatcaaata tgaacgaatt
    10861 agatatgaat cattgtattt gccgttgcgg aaggattttt taattaacca cagataaaca
    10921 ttgataacga ttcgcttatt gtaatcaaca gattaaattt catatgttca tatgtacgga
    10981 tacattttcg gaccgattaa ttttaaccat tctatttatt tgcttaccta ttagatatca
    11041 ataaaaaact gcttaacagc tatttcagct gttaagcagt tttaggattt ttagttcata
    11101 ttcattgttt cttataatac agtgttcaat acttctctta aagcacttgt tgatttgctg
    11161 aacattgctt tttcttcttc gttgattgat aattcaacaa cttcacgaac accattttcg
    11221 tcaacgattg atggcacacc tgtaaagata tctttttcgt cgtattcacc agttaaataa
    11281 gcagatacag gcaatacagc ttgttcgtta ttcaagatag cttttacgat acgtgcagta
    11341 ctcataccaa taccatagta agttgctttt ttacgatcaa tgatctcata agcagcatta
    11401 cggactttat cagcaatcac atctaattca tcttgggcaa tacgatggtc tttttctaca
    11461 atttcaaaca ctggtttacc accgacagtt gtatgtgacc atgcagcaac ttctgaatca
    11521 ccatgttcac ctaagatata gccgtggacg ctgcgtgggt caacttttaa tttcaatgcg
    11581 atttctttac ggaaacgagt tgtatccaat gttgttccag taccgataac acgtgatgtt
    11641 ggcagaccag attcgttcca agcgatatat gtcaaaatat ctactgggtt tgaagcaaca
    11701 acgataatac cgtcgaatcc tgatcccatg atttctttta cgatttggcg catgattgac
    11761 gcatttgttt taactaaatc taaacgagat tgaccaggtt tttggttgat accagctgtg
    11821 ataacaacga tatcagcatc tttacattct tcatagccac ctgaccatac agccacattt
    11881 tcatcgcccc aagccatacc atctaaaagg tccaatgctt ccccttctgc tttttcttga
    11941 ttcacatcga tcaatactaa ttcattagag attccttggt tgatcattgc ataagcgata
    12001 cttgttccaa caaaacctgt accgacgatt actactttac gacttgtttt tttcatgaat
    12061 aaacagctcc ttttcataac tatttgttac tttcatgaaa agtatagtct tgtttattca
    12121 ttttatcaac atgttaatta taatagttgt tattataatt tttgatggaa acgaattcct
    12181 gaatacgcat aacagataaa tgacaaatgt ttacacctat atcccctgat aatacaacca
    12241 aaagtttaga actgaaaata aatccaaaaa aattcgctgc aacgatataa taagacagca
    12301 atcgcaccta aaacaatttt ccttcatatg ctttagtgaa agattttctt cttaatgttt
    12361 atttctccat tcattgggag tacatgttga atacttcttg aataatttga ataaagaagt
    12421 cgtttgttta tatccgatac gattagcgat ttcttccaac gaaaaactcg tttcttgaat
    12481 cagttccaac gcaaagtcga attttttctt tagaaccagt tcttgaaagg aagcatcaaa
    12541 atacattttc aatttattac taagatagac cggattgtag ccaaaatgag ctgctgtttc
    12601 ttttaacgta caagaagtaa aatgcttatc gatataatct aatactctaa gcatctcatt
    12661 ttctgcgcat ccatctgctg atgaaaagct ttgttgttct aataaatgag tcaattcgat
    12721 cagtaatagt gatgtataga gatttaacga acggatctta tgactgtatg tatcaaaata
    12781 aatcaacagc atattttcaa tcaaatgcgt caaacgactt gtttttccgc cgcgaaaatg
    12841 aatgaattgt gtatgttccc ctttttcttt tgatgcattt atcaaaaaag aagaaagtag
    12901 attatttgtg cttgccaaat gattcaatat ctctgtagat aaggtttctt cttttaataa
    12961 gatgttgatt aaaatatcct cttgccctgt gtattcgatt ctttgagtag cttctttatc
    13021 aatgatcacc acgtcacttt cttccatctc tatcctttct ccattaataa tttgtaaaca
    13081 tgtaccgcta tacatataat tgatttcaac aaaatcatgt gtatgctcgg gaacttccgc
    13141 atatcgacgg tgtttactga tatgaatatt tccctgttga aatagatccc ctcggtggat
    13201 ttttggcggt gtctgaagat ggtaagctaa gtttaaatca ttgatattca ttccttgttc
    13261 acgctgcaga gtttcgattg attcttcgtt acgcaaaaaa aatgtctaat tcagctagtt
    13321 ccaattgact ccctcctttt tgtaagcggt ttctttcgct tattagttca cgctgtactg
    13381 ctattatatg caaagctatt tttggtttca taaagacttt ctatggttgg gacatgaact
    13441 tcctgtgatt ccgctattga gagaataacc acttcatact atatttttga taagcgctta
    13501 caaaaatgaa aggaacatgc ttatgaataa aaagatgatg aaattttctc tgctgtcagt
    13561 ctctcttatt ttgacttctg ctggtgcagt cacgtctgca attcccagta tgtcagctac
    13621 ttatgccacg cgttctttat ctgctgttga attattaacg actgctccct cttttatggt
    13681 cactattttt gttttgatta gtagttttat tgctaggaaa atcggacaaa aacaaactgt
    13741 gatcatcgga ttagtgattg catcgatttg tggtatcctc cccctcttct cacaaagtta
    13801 cagtattgtc ttagcttcaa gagctggact aggtattggc tttggattga tcaattcttt
    13861 ggcagtcagc atgattgctg ccttttatca cggagatgaa cgagcctcta tgattggttt
    13921 tcaaagtgca tttcaaggat ttggtgcagc tttaatgaca tttgttgcag gacagctagt
    13981 acagttcggt tggcaatata cctttttagt ctacgccatc agcttaccta ttcttgtctt
    14041 gtttgttttg tttgttccta cacctgaaac aactgaactt caatcgcatg gcacagcccc
    14101 aacaagacaa gtaatcaaaa cgaatcctaa aatgattagt tatggtattt ttctcttgct
    14161 ggtcatcgtg gtatataatg ctgtatcgat taaattagcc acagtcctga cgacttattc
    14221 tctaggaaac gaaactaatg cagcgaatat cttaacaatc atgcaattgg caagtatggc
    14281 tgccggagtt tgttttggct ggcttcagac aaaagcacat cgctatatgc ttacactttc
    14341 tttactactg atgggaatcg gctttgtatt gattgccact gtgataaacc tgtatgtgat
    14401 tgggtttggt gcgatcctaa caggaatttc tttttcgtta ttcattcctt acttattcaa
    14461 ccaagtaagt atccaagcgc ccaagtacgc ggagagtttc aatacttcaa tcttattggt
    14521 tggcgctaat ttaggtactt tcattgcacc atatggtttg ctctttctct cttttgcttc
    14581 tcttgggagt aaaacacttg ctgttttcgt caatggcagt atcttgctgt tgattagcgc
    14641 gcttattagc cttctagtag tacacaggac gaatagaaag acagtgataa gagtagatga
    14701 agaaataaaa gaacaattga caacaaaata aatttgatgg aggtcgtgta aaatgacaaa
    14761 tgaaaaacat aaagatagat ggctttggta tcctggagac tttgagatcc gccatggact
    14821 gctacaaaat ttccaacggg aagaacgagg ttttgactgg ccagcgtact ggtacatgga
    14881 tgattgccat cggaacgtca agtttaagag atattacttt cttgatcaac cttccatgtt
    14941 taaagtgacg atccaaggag ttgggtatgt agaaattaat ggacaaaaac atccatgtgg
    15001 aaaatggctg acttgtccag ctggtaaagc aaaaattcgt atctttgtag gacatacatc
    15061 agggctacca gcgatgttta tcgagggaga cgaagtaaaa tcagatattg gctggacagc
    15121 aagtaatttt attgaagaat atccagctgg ctggagtccg ctttatgtcg atatcgcaaa
    15181 agatccaaat caaatctatt atcaaaaaga atgcgtccat ccagtcactg aaacggagat
    15241 tggcggagga atcttattcg attttgggcg agcagtgaat ggctgtgtag aactaatatc
    15301 tctggatgac catatcgaat ctatcactct atgttatgga gagtccgatg tagaagctat
    15361 ggatatcgat tattgctact ataagcaaat aggaatgaca agaaaaatga aagctcgtaa
    15421 acgcgctttt cgctatttgt ttataccaga ggtttctact ggaatggttc aacttcaagt
    15481 ttttcatgaa tttttatctc tttcgaaaca agctgctttt tcaagcgatt cttctttact
    15541 gaatcagatc tggtcagtat cagaagaagc cttcaagtta tgtagtgatt tgttttttat
    15601 cgacggtatc aaacgagatc gctggatttg gtctggagat gcgtatcaat cattcatgat
    15661 caatcaatat cttttttttg acgaggaaat caataaacga acgatattag cattaagagg
    15721 acaaaatgaa atcaagcagc atatgaatac tatcgttgac tattcgatct tgtggttgat
    15781 tggtatcgaa aaccactata tgatgacgaa agactatgaa tttttacgca tcgtctaccc
    15841 taagatgcaa tcattaatga gatacttgat ggagcaaacg aatgaattag ggtttattta
    15901 tgggagagca aaagattgga tatttattga ttggtctgaa atggataaag aaggaacgct
    15961 tgctgcagaa caagtcttat tactgaaagc ctatcattcc atgatcactt gcggagatat
    16021 cttagctgaa acatatggag agaacgaaaa ttatcatact catctctatc aagaaaaata
    16081 tcaactattg aaacaaaacc tatttgacta cttttgggat gaagaacttg gcgcttttat
    16141 cgattgctat gaatctggga gaagaaatgt gacgcgtcat gcgaatattt tcgctgtttt
    16201 attcgatttt gctaacaaag accaacagca atcgatctta aagaatgtct tattgaatga
    16261 cactatcaca cagattacta ctccatattt caaattctat gaacaagatg ctttatgcaa
    16321 actcggacag acgaatatcg tctaccaaac gattcttgat tattggggag ggatgttatc
    16381 tcatgatgcg gtaactttct gggaagaata cgaccctact caaacaggaa atgaaaagta
    16441 cagtatgtat ggagatcctt atggaaaaag cttatgccat gcatggggag caagcccaat
    16501 ctatctttta ggacgctatt ttatcggttt gtatccaaca aagccaggtt atgaagaatt
    16561 tatgatacaa cctaatctag attcatttga aacactgaat tgtacgctac ctatcaaaga
    16621 tggaaagatt tcgcttgaaa aaacaaaaga taagatcgtg attacttctg atagaacagg
    16681 cggaacagtg aaaatgaatg gtaaaagtta tcctcttcta gcaaaacagc cacttgtctt
    16741 aacaagctat tcaaaaataa atgcataaaa caaaaaactg cttgcgacat atcagaagac
    16801 tttaaatctt cttctgatat tgtccaagca atttttattt tgaagtttgc ttaattctgt
    16861 tctttagaaa caatgtttgt tctttttccg gcaaaaagaa agctagataa tacgacaagt
    16921 aaaaagaaag cgatgattcc aactgtcaag gctatttgac cgtattctcc tagtttccca
    16981 agtacaagtc ctggtactag ataatcagta tcggcaaatg tagaagaagc gattttaaga
    17041 tctcctaata ctggaaggat aaataatggc agccaactaa tcaataagct attgaaagca
    17101 gaacctaata ccgcccctct tctaccgcca gtcgagttgc cgaagacacc agaagcagct
    17161 ccgcagaaga aatgtcctac taccccagga atgataactg tagtttgcaa gcctatcata
    17221 gcaaacatgg atagtgttcc tacaaagaag ctaacaaaaa agccaattaa tacagcatta
    17281 ggtgcatatg gaaaaacgat aggaacatct aatgctggtt tagaatcggg tacgagtttt
    17341 ttagcaatcc cttggaatgc tggaacgatt tctgccaaca ccattcgaac cccttgaagg
    17401 acgataacaa acccagctgt gaatgttcca gcttggatca gtgcaaagat tacagcgttg
    17461 tctccattgc ttagttctct ttcaacaaat ccaggaccag ctaacaaagc aagtgcgaca
    17521 tatacgatcg acatcaagag catgatcgat acagtagaat ctcgcaaaaa gctgaaactt
    17581 ttaggaatct ttatgtcctc tgtagaacgg tctttgtttc caaaaaactt tccgatccat
    17641 ccactagaag cataaccgat atttccggta tgccctaacg caacttgatt gtttccagtg
    17701 atgttcttca taaacggttg acaaagagca ggcgtaatag ttaatagtgt tccttcgaag
    17761 accccgccta ataagatcat ccacaaattt gcagtaaacc ccgcgcttac taaaatgact
    17821 gctgttagac aagaaacata aagcattgct tgacctgtaa gaaaaatgaa tttatatctt
    17881 gtgaatctag caagtaaaat attcacgatc atccctacta gcatgatcaa agcagtaggt
    17941 gtaccgtatt gttgcaaagc aatcgccact actgcttcat tgctaggaac tactccttga
    18001 gtatgcagag ctgtttggaa catcgaagca aaaggggtta gtgaattact gattaaacca
    18061 gcaccgccga tcagtactag gaatccgaca aatgttttga tagttccttg gatcacttct
    18121 gaaaatttct tcttctgaag aacgagacca agcagtgcaa tcaaagaaac gaggatggag
    18181 ggctgactga cgattgacac aaacaaattc aacaatttat ccattgatag ttcctccctt
    18241 gaatcatttt tattcttttg acaagatctt cgttactttt tcttttactt cttcgctgtc
    18301 aatgatcgat tgcaaaggta cgagcttttc atcaggtata gaagttagcg tatctttcaa
    18361 agaatgctca atgaagaaat aatcagccat atcgctagat acacttccaa catccgtatg
    18421 acttacttca aactcgtcca catctgctcc aagatctgca agtgcttgtt tgatgttcat
    18481 ctctaccata aaacttgttc ctaatccact ttgacatact gcaaaaattt tcatatcatt
    18541 cgtctccttt tcttatgatc gctaatattt cttcttttgt tgatgcgtgt aataaatctt
    18601 gaagattttg tttattagaa agtagctttg ttaaatttgc caaagcccga agatgtgcct
    18661 cattatcgat agcagctaaa cagatgaaca aactaatggg atgggctgga ttatcaagca
    18721 gatccacagg ttgttgaagt ttcagcaaag acatccctac ttcgtttacg ccatcttctg
    18781 gacgagcatg aggtaatgcg atgtgatcgc caatatggat aaacgcacca tactgctcca
    18841 cgcgctcgat catagctttg atataacttt cttctatttt attttctgat aatagcggct
    18901 gtgcggcaaa tgtgattgct tcttgccagt tttttggttg atccgataat tggatcattt
    18961 cttctgttaa taattcagat agcataggac gttgatcctc cttcttttct aaaagtttgt
    19021 tcattttacg atttaatact tgatagagct tttcttcgtc tacgccttct tttaattcga
    19081 tataaggcag tagcgccgac aacaattctt gggcagaagg cattgaaaat cctggtatca
    19141 gccaatctct ttgtacttga ttgatcagct gatttttttc caagtcagtc atgattggat
    19201 gcagaacata gagagacttt ttcttatcag taagtgtgag aggtacagta gaaaaaataa
    19261 tatcgtaaga agtttcgtca acctcgtgta agcggtcagc tgaattagtc tctgtaaaaa
    19321 agatcatcgg gaataattgc tgaagttcac tttttaagat caatgaagag ctaatgccac
    19381 ttggacagac gatcacggct cttatttttc tatttctttc ttctgcgtcc gcttttctga
    19441 tctctccgcc aaatagtata gtgaaaaaac caatctcttc ttcagggatg ctcttcccta
    19501 ttcgtctttc taacggaagt aatgcttttc ttgtcatttc gtagatggaa gcatattgat
    19561 gcttaatttg atcgatcatc acattaggta aataaaaaga ataggaaata cgaaaatagg
    19621 cagggaccaa gtgataaaag acattcatca ataattcacg aaacgaagca aattctacgg
    19681 ccatcaggaa ttccatgcga tggatgactt ctgaagaaca ttccagcaaa aaatcaagtg
    19741 caggctcctg gacatctcct tcaacgatcg atgctaagca aagagagaaa aatataatct
    19801 ccgaattttg atgttcggaa tagccaaggc cagtcaatac ttgtcgacta atgtcagtga
    19861 ctgcaagaga agccaacagt tcagcatctt ttaccagttc catggatgtt tttccaattc
    19921 gaatggttgt caaactcaaa taataagcta attcatccat tcgatttggt gcgaatcgaa
    19981 gatctgatag tgaaatcgtt ttatctagca aatctctaac tttggcgtaa taatcaatgg
    20041 aaagggttgc ggttaaatac gtgagcccaa atcttccagc aagtgactgc atcaaacgag
    20101 cagtgcgatt ttttgcttct cttcttaata ttgcttctga ccctagcagc ctaaaaccag
    20161 ttttcctagt atacgacagc tgacaatctt ccacttctaa ttcatttctt atctttttga
    20221 tatctgacag gactgtccct ttagaaacct gaagaaaatc ttgaaaatga aaaacagaaa
    20281 cagacgttgc agtcgaataa accatcaaat aaagaagatc tcttcgctct tgttcggtat
    20341 acacagcttc aaatcgagta atatccaaaa atttttctgc ccagtcgatt gctcggaatt
    20401 tctttatacg gatacgggta tcatccacat attcggcaaa aggagttaat tgtttgatcg
    20461 cctcgcttgt atttacttcg atgatctctg ctgctttttc tagactgatt tctcttggtg
    20521 ttttcaggag ataactaatt ttgtagttca cagcgctgtt cacctcctac ttatattcta
    20581 gtatggtagc gcttttaaat cgaggggtgt ttggtacaac ttacagttgg atttttttta
    20641 cgactgtacc gaacgatttc tatcgaatgg atacagaaaa aaagcaggtg accaaatgtc
    20701 tcctgctttt atgaattgat ttcgtccgat caatgatgat catgtttatt ttttgaggtc
    20761 agttcttcaa atttttcttt gacatcttca accgcttttt cgatatcttt ttcaaagtga
    20821 ttgggctcat taggctttgt ttcctcttct acagaatttg aaccagataa agctgtttct
    20881 ttattttctg tttcaccaga gtttgtgcca gctaatgatt cttctttgtc ttctgtttca
    20941 ccagaattag ttcctgctaa agccacttct tcttctgttt taggggccat tgaacctctt
    21001 aatcgtttgt gtttttcacc gtcataattt gtcatgttgg ttcctcctag tagttctata
    21061 ctttttcatc gtacaataag acagtttatg cgtcaaaaaa caaacccgat tcttacaaat
    21121 atgtcatatt tttccttctg attcttgaat gcttttgatt ccttcttcca aaattttcat
    21181 ttgtaagatt gtttcttcat ctttgatgac tttttctgcg ccattaacta atgtctcgta
    21241 aatcccttcg tagacacggc tgtaatcacc aacctcggaa attacttttt cttcatgata
    21301 actcccttgt tcatctatat aggtcaatac accataatgt tcgggcaaat cgataccaaa
    21361 gtcttcatga tcaggcatgt aaaacatttt cagatgttct tcttgtcgat cttttgtttg
    21421 tttcacgaac atcccttttt ttccgtaaac gacgaaactt ggacgttctt tgatgcggaa
    21481 ataactggat tttatcgaaa ttttcatatt tccatagaaa aaatccagat cgaagtaatc
    21541 attcattcgt cctttcccta aaagttgacg tacatcatag ctgatatcat ctggttcgcc
    21601 gaaataagaa agaacttgat ctactgtatg acaagcatgt ccatataaat agctgttcgc
    21661 agtagaaaat tcatgcgtat tttctggtac ttccggtctg aaataatcat aatgcatttc
    21721 tacttctaaa atatccccta attttccgct ttcgattact ttttggactg tcaagaagtc
    21781 agaatcgaac cgtctgtttt ggtaacattg gataaataga cctttttctt ttgctaatgc
    21841 aaataactct tctgcttcct ttgacgtttc tgcaaaaggt ttctctacta gtacattctt
    21901 accatgttcg agtgccattt ttccatattc ataatgaaat tgactaggtg tagtgatgac
    21961 aactaattgg atctcaggat catcccaaag atcagacagc tgatcagtat attcgatgtc
    22021 ttcgaatgtt ttccacactg gttcagatgg ggaaaaaatt tttttgatat tgattttgtt
    22081 cgtaagtttt cttgaaaaag gcaaatgata gcgatttgta ctctttccat tgccaagata
    22141 agcgattgta agcatgagtg gtgcctcctt ttattgatgt tttcagtata tcctagaaaa
    22201 gcgcagaaag tatttataat agctattctg gtaaaaaagt tcagaaaaac acttgttatc
    22261 attcggtttg gtgaaattaa tgttcaaagt aaggataaaa atcaaaaaga tagtagcgga
    22321 accaagtgtt tatcagtaag atagaatttg gaggtcagat catgcttatt gaagaaaaac
    22381 taacaaaaca agagttgttt accacgacag agaaacggat tgtcgattac atccgtagga
    22441 atatcgaagc tgcagtctac atgacgattg aagaattagc aaaagctacg tatacttccc
    22501 attcagctat cattcgttta tgcaaaaaaa tgggattcag cggatttaaa gaattccgtt
    22561 tcgagctggg gcgggaagtt catcaattga ttgctcagtt caatcaaacg attgatccta
    22621 attttccttt ttcaagtgaa gatagcactc agcaaattgc aaagaaaatg gcggatttat
    22681 cgatccagtc aataaaaaaa gcacaattgc agattgaaca tgaagattta gatcaaatcg
    22741 gtaaagtatt gaacaaggca cagcgaatct ttctttttgc aaaaggtgat tctcaaatca
    22801 cggcaaggaa attccagaat aaaatggtca agttgaataa gtttttgatc atggctgaag
    22861 aatacagtga ttcttcttgg aatgcagcca atttgactag cgaggattgc gccattttta
    22921 ttagctacag cggtcgcatc catcattatg aacgaataat gacctatttg aagcatgtag
    22981 aggcccctac cttgctgatt accggaaatc agcattcaga aatggccaaa caggctgata
    23041 tgtgtcttgt tatatcgcag gaggaatatg attttgctaa agtagcgact ttctcctctc
    23101 aaattgcctt cgattacgta ttaaatacgt tattctcagt gatatattct caaaattttg
    23161 aagagaatat ccgcaacttg aaaaacaaac aagaattgat gcaaaaaggc cttcttaaag
    23221 aatatcggaa aacttaagaa aagatcctca tttagtaata agaaagatag tgtttgatag
    23281 gctctctttg atatcatcat aaaaacaggc tgaagttttc tttttcaaac ctcagcctgt
    23341 ttgtttacgg aacgattcga atagatatat tatagaaatg aggaatagct aacttctgtt
    23401 tcttattttg aacgattgac gaaaaagata tataagaagg aggaaaatca gtatacatgc
    23461 agctaacaat ccatacagga aaaatcgttt gttctcggat actttctgta cttctttttg
    23521 aacttctttt gcatgataag gaacccggtg ccctctgaca agtaagcgat gactgttgac
    23581 catataaggt gtacaagtta ggagtgtcac gaaatcctgc cctttttcga ttctcagatc
    23641 ttttgtatca gtcggttcta ccgtcttgat ctgatcgact tgataagcga gtgtccgtcc
    23701 attgatttcg atatagaaag aatcacctaa agtcagtttc ggtaagtctg tgaacaactt
    23761 tgcttgaggc agtcctcgat ggctggaaat aacggcatgt gtattttctc cccccgtagg
    23821 ataagacgtt ccttccaata atgaggcacc tttttctagc agcacagtat tcgtttcatc
    23881 aaaaattggc aaatggacat tgatctcagg gatcgtcaaa ataccgatcg tatgtttctc
    23941 aaaataggtt ctatcctttt tcgcaggttc ttttttctta gtaaagggat ctgcacctgg
    24001 atttccacct tcttttgcta attgctggtt tttctttgtc atgttttctt ggattttagc
    24061 catgacttct tcattttctt tgaccgcttg ttgctgataa tgagagatga tctgctgatc
    24121 cagataatta ttcagcgcgt cgctaacaaa tggataagct agtatcccta ttcctgagag
    24181 aagcaagaaa agcatcagca gatctagaag tttccttttc tttggtttca tttgtgttct
    24241 ccttgtgatg actgtttgat aataaaagaa aaaggagcat ttgcgtaatc cgctgctcct
    24301 ttttccaatt cttgcaaaaa gactaaatct gactgtgctt gcgtctagca aagtacagtc
    24361 cagcaatcag tagaaggact actcctgcac cgatatacac atagattccc ttaccgcctg
    24421 ttgaaggaag tgtacctttg tgtttatttg gtattttttc aggagaaatc aactgtcctg
    24481 ctgttacata agattgttca tcgatagtaa atgctacacg gtttgttaat ggaacatatt
    24541 tttctggcgc tttcgtttct tccagatagt acgtgccata ttttagacct gtcacatcga
    24601 ttaaaccgtt acttgtggtt gtaaaaaccg ttgctgattc tttcgccgat acccagctga
    24661 cggcttttgt ggatgggtcg atcgataaat atttcgctgt gtcactatct tgatcacgaa
    24721 cgacgaattc tgctccagca agtgtttggt ctgatgtaac gtcaccatct actttaacaa
    24781 atcgtttgcc cccagtaacg acatcgactg acggtggtgt ttgatcattt gtatgcccgt
    24841 tatcgacatt tgcttggtta gaaaatcctt tggttggatc tgctttttcg ttcaaatgca
    24901 tatagtaaac gaatttcaat gtaccgccag gagttaatga aggaatataa ttcggatcaa
    24961 ctgaaaccgt gaatccgtct gtttgctcag tgacagaata atttactggg tcgatttctt
    25021 tatttccatc atataaggca taagcatacg ttcctgaaga atcattatca aatgttaaag
    25081 cagcgtcatg agtatcgata agtttgaatg ttgtgtactt gttttgcgtt ccttctttat
    25141 cagcgatacc taatgggata ttgacagaaa tctcatattg aattttttca ccgattgcga
    25201 catcttttcc attcaattga ggtgttgttt tatcaacttt agacgtatca tttttgatgg
    25261 tcttttctac tggtgtttgg ctatttgcca ggatctcaaa aggcgtgatt gtttgctttt
    25321 caatcatttc cgcattatca ggagctttta cttcttctaa attatatttt ccaacttcta
    25381 aatgattaac gatcaactgg cctttttcaa tagatgcctc ggcaaagtca ttgttgccga
    25441 tgtcataaga atgaccagta atgaaatgtt tggctttggt ttgatcagtt gtccaagtgt
    25501 acaatccatc tgtgacactt tggatgtatt ttttgacgct tggtgttcct tcttctttag
    25561 aaataataaa ttctgctcca tttagtgctt cgttttcggc agtaccgatt tttgtaactt
    25621 tcaacgttcc atcattaccg actgtatttt tagggtagag atggatagta tctagttctt
    25681 ctgtcccgta tttataagag ccatctgctt gtttgatcat ctcatataca gggaaagcta
    25741 aaaccatgtt tgcggcagct gacactccgt cttttggttc ttctttgatc gtgtagactg
    25801 catctttccc attttgtttt ttaggtaaag ataaagtgac atttccatca gcatctgtcg
    25861 ttcctgaagc aactggtgta ccaggagtca aagactggac tgcttgtttt gctgcatcca
    25921 cggacgctcc tttatctcgt tgcgcataaa attcttgagt gacgttataa actgaaaatg
    25981 aaatatcggc taatccttgg tattgatcga attcgctcat ttctttcccg ctgttttgga
    26041 ttaaaggatc gggtaaatca gtcattttct ttttatgaag gatgacttga gctgctgtct
    26101 cctctgcaaa cacttttttt gcgccgaagc tgtttgtgag taatggtaaa ataaggaaaa
    26161 ggactcctaa cataacgttt atttttttat gatttttcat tttttcactc ctgttctttt
    26221 tttgataaac aaccagattg caaagcttgc gaataccata ccaacaacgc ctaaaagtgt
    26281 atttttcgtt tcgtttgttt ttggaagaaa tggacggcta ttttcttttt tattgactac
    26341 tttcaatata ctgtccgcct ctttatcctc agaaagaaaa gttgaaatgg taaacggaat
    26401 ttctgtttca cttaaaatat aaccagaagg tgcttcgatc tcttttaatc gataacttcc
    26461 tgttttcaac ccggaaattg aaaaagcgcc atttttatcg gaaatcaggt gaagcgcatc
    26521 tgattcgttc tttgtccact tgtatccgtt ggctgtttgc tggaggtaat ttcctgcttt
    26581 gtttttaata aggaatactg cgccagctaa tcgtttatct ggtttatttg tctcgatttt
    26641 gacaaattgc ttactccctg tatatacaga gactttcttt gtactgacac caaaaccaaa
    26701 atccagtgtt ccgttgttgt tgatttcctt gttcgcctgt gctgtactgc ttagctgcat
    26761 ccgataagaa atggtcagtt tttttccagc atatttttcc aacgaaggga tcgaaaataa
    26821 aacatcaaat ccgtgaggtt tcttgtgtat gacaaagcct tctgtcagct tttctccatt
    26881 cgatgaaatc gttaaactat taggtaaaaa cgttaatgct tcatccgcac tatctgacaa
    26941 ttcgaacttt tgatagtcaa ggatatttac aggaattgtc gtatgcaagg aataagtgat
    27001 tttttcacca atcgtaaaat catttctagg ctcttctaat accttctcaa aaggtggatc
    27061 agggtagtcg ttttcttcat ttttaggata caaatggata gttgaaagtt tttgattgtt
    27121 ttgtccatgt acaggaagaa caactaccat attctctgcc ttttctttga cgacttctgg
    27181 tactttggat tcaatgaaaa gatacgcttt atctcttttt tcttgatctt tagcggccag
    27241 agaaaaagaa gcgataccat cttcgttgtt aagagttgta gttgttgctt ctgcggtaaa
    27301 cataccggaa gacgcaccgt tttttgcgat ctctgcttgt gcttcttcta ccgttttgcc
    27361 cttttcccgt agatggtaaa aagaatctgt gacatcataa acttggaatg tgacaccatt
    27421 taatcctcga tacgtttgta ataaagcttt ttcttgtccg tcatttggat gatttttcgg
    27481 cagttgcccg tttgggaaaa gcaatttgtg taaagtaatc tgaaccattt ctgtttctgt
    27541 ttctgttgct acctgagtaa aagctggttt aaatagtaac aagaagagac acatactaag
    27601 ccaaccaagt tttttcatat ttagctgccc cctctttctt ttttcaaaaa aagataccaa
    27661 atagaaaacg cacaaccaat catccctact agatagattc ctaaacggcc aattcctccc
    27721 gtttcaggta atggtacttt tgcctgattc gtgatgtcta aagaaatctg gttgtttttg
    27781 gctcctggtg acagaacaga ttcatgatct tgtccatcca cttgaattga cccatcttcg
    27841 tgtataacta tagtaactgg ctcttttaga ccttggtatc cttctggtgt aaaagtttcg
    27901 gtcagcgtat aagttccagg ttttaaattt tcgaatagaa aggtatctgt ttcttgtcca
    27961 tcttttggcg attctaagtc catttctggt ccctgcagtc tgaattttgc tccttttaat
    28021 gtctgtccgt tgtcttcttt tttgtgtacc gttagatcaa acgcttttag tcgattttga
    28081 tgagtgagcg tccatacatt atttgtcatc tcggtatttt ttcccgtgta aatgattttt
    28141 ccatatttat cgatttggaa ttcataattt cccggcgaag tatcatatcc ggcaggacca
    28201 gctgtttcaa cgactcgata tttaccaggt gtgagtgaat caaaactggc aagacctttt
    28261 tcattcgttg tttggctgtc aattggctga taagtaccat ttgcttcttt tttctgtagg
    28321 gaaaatgctg ctcctttaag atttatctct ttgtccgtcc cttgcatcgc atacttacgt
    28381 actgctacag gaacttcaac aaaaggattt tcaatagtca actggatcgt atcatcggaa
    28441 gtagtgactg tttttccatc aatggttacc gtaccatcag aagcgatctt gatttcccaa
    28501 gtagtctttt tgcttaatcc atgcccttct ggagcttttg tttctgtcag cgtataggtc
    28561 atttcttttt gcaatttgac attttctgga agagaatagg ttccgtcgcc atgatctgtt
    28621 agtaaagtat caatagaatc tcctgttaat ttgaaaacag cgccaataag atccttttca
    28681 cctgtagagg aatttttcgt tattttcaag tttaacggtg tgaattgttt agtatttttc
    28741 catgtcattg catctatttg ttgagaatcg tatcctggta caggtaattc tttgattgtt
    28801 tggtaactga atgcttgacc ttgattattg tattgaggta gtgataatat ctcttgataa
    28861 ctttctccgc tatttgcaga taatttgtca atgtctgcac gttcccacgt atttgttgta
    28921 tctttagctg gtttaatgat tcgaatatat ccgtttttcc aagctgcagc atttgtcgta
    28981 tgttcccgtt gaatctcaaa agtaacttga tctggacgat cagctagatt gttgtcaaat
    29041 tcttcccata actttttgat gtgaagactg actccgggag ctttagcaga tggtataccg
    29101 aattcagcta attcattggt atcaatgttt ggctggaaag ttgtcctgcc gttcatttga
    29161 taccagaaat ttggatggaa gtcctcattt tctgtttgga ttctcacttg gtaatggatt
    29221 tggatttctt ggtcttttcc taaatagatc tgattgctct tgatggtatt tccttctatg
    29281 gaaatagatg gagtgaccgt tgtaggactt gtccccacac tcttgactga aagtgtacca
    29341 ggctgataaa tgaatggttc tgcgattgga tcatttattt gtccattgct tacagttgct
    29401 gagatctgta cagctttttt ggctaggtat tcagagatat ctgttgcatg atcagctgat
    29461 tcatagtaaa gatcgccttt ttcatctgat gaaaccattt gtcgcatacg agactctact
    29521 tctgcttttg agagaccagc tgccggatcg ctttgaagtt ggatgccaag accatgtatt
    29581 tcgattcctc gttctttgag tgccatcgct tctccgatgg ttgcgataaa cgtactgtcg
    29641 attcttctgg atagattgtt ttggtcaggt gcatcataga ttcttgagat tagagaagta
    29701 tttcccggcc gatcttgcgt attagaaaac tgagttccgt aataattgct gcttgattgt
    29761 gcgtgtaccc gctgtacttt ataggaaaat gttggtacac catccgtcag caaaacgatc
    29821 acttttttat gtccatttgg aacggatagc atgcttcctg catctcttag tgctttttgt
    29881 gtaaaagtac caccatttgt ccgtgaaggt gtaatggatt ttacttgatt tttcactgaa
    29941 tcaaatgaac ccatctgtac tgcaccgtta ctgtagctat atccttcgct tgagtagccg
    30001 acatatccca tattgatttt gtctgtgata ccgctatctg ctaaagtatc gacaaaacga
    30061 tcgacaccaa tctttacttc accgatccga ttattgtcgt tcatacttcc tgaccagtct
    30121 acgaccaata cgagatcaag aggcgtgata tctttttgta catttccacg agcattcaaa
    30181 taaacatcaa acaatccggg tgtacttgtt tcctttgcat actttcgtat cgcatagtct
    30241 gcttgattac cggttcctcc atattcgata tacgaatggg tccgatcatt aggatctcca
    30301 ttccaagaat ttataccatc ccattgattt gttccgtttt tattgccttg atgatcaaga
    30361 acatttgtat ttcctgtagg ttgccaactg gctttaggat aagtgccctg atcatctgtt
    30421 gtatattctg taggaatcgt ttgattagat ggcacactca cagctggcaa ggataatgta
    30481 ggcaatgtaa atgggctgac agaattttcg ttttcttttg atgattcttc ttctatttcg
    30541 tctggctttg gtactgacac atctgtatct ttcttatttt ctgtctcatc aataatgtca
    30601 tattctttat tatcgacgat cagcttgttt gcctggctgt ggtaaagtgc tggatcgatt
    30661 ggaaaactca gatcgatagt ttgtttagtg tttgatgaga tttccaacgt aattttcccg
    30721 ctatttacct gataagcata gccatctcct tcttttcttt ccacatcact taagtaattt
    30781 tcgactagac caatttcttt ttctatcttt tcagcactgg tgttattcgc atttagcttg
    30841 atgttcagtg ctttttttcc agactgatcc gaaatgactt cagctgaaat tgtttctaaa
    30901 actgttggat catctgtagt gtctgctatt gcagataatg gcacaaagtt tgataaactc
    30961 aatattatca gcatgaaaat aactttcagt ttcttccctg tggtcgtcat ttttcccctc
    31021 ctttttcttt ttttctgttt tgacgtgaat agtgaaaatt attaaaataa acaggcgtta
    31081 cataatttta tttattttaa tatgataatt attatacgaa gggcgctaaa gggaatcaca
    31141 ccaattttca taccaattgg tttcatttat gaagttgatt ccttcgatta atgagcgttt
    31201 cattgaaaga aaagggttga gggagaaaaa catatgatca ggttgttgga attaaactat
    31261 agaaagatgg aaaaaatcat tcgaattctg tccatttctg acaagtggat gactaaaaaa
    31321 gaacttgcca aacgaattgg tagttcagaa tctacatttg taaggtatat cgaagagatc
    31381 aaaatccgct ggggaacgga tgtaacgatt caatcttcac aaaaattggg gtatcgtctt
    31441 gaacatttga atgtaccagc ttatttaaat gttctgatgg aaatgtcgca aagttctaca
    31501 aacagtcgtt tattaaatga gattattgtc aatccgggta aaacgattga gtattattgt
    31561 gaaaaaattt ccatcagccg gtcttctttt acacgtaagt tgaaacaatg caatcaaatt
    31621 ttagaaagct atttattaaa agtgatcgtt gaccaaggtt ttcagttaac tagccttaaa
    31681 agtgagctcc agttgcgtat ctttgttacc tttttctttt taagttacta cggaagacgc
    31741 acgttgccat ttccaatcga aaaaaagaag atcaaagaaa ttatggtcaa gaataattgt
    31801 cagatgaatt tgtttcagga agaaagccca tatgagcaat ctttctttat tatgtatttt
    31861 gttgtgcatc tcatgagaga atcccaagga actccatttg aatggaaagc tggagactct
    31921 tatgtacagt tgataaatat cgataaaaaa gacttcttaa tcttgaaaaa tctcttagga
    31981 aaattgaagt acagcagcta tataaaagta gtgaactatt ttgtcaatac gattttttca
    32041 gaattttcgg agaaagaaaa aaatgaaatc agtgagcaga tacgaaaaaa tatgtcctac
    32101 tgttcgtttt catccgctga ttgcaaagaa aaaaacgaag aatatgttgt tcaattatta
    32161 acgcaaattt attttttctc ccgtattttc ccatacgata cgactcattt gacgatccgt
    32221 gcaacttact ttgcacagca gatgcaacac cgccagatac gtctatatgc tggatttcgt
    32281 gcagaacttc aattttattc cactctactg aatcagaatc tgatttatta tttatctagc
    32341 tatatctttt ggatgcttat cggtaatcct gaaattcacc attatacttc tgataaaaaa
    32401 atactgatta tcagcgactt aagtcttcga catagtcaat atattgaaga atatatcagt
    32461 gatattcttg ctgtgcataa aattcactct gagacaactg ctattactga agatcagctg
    32521 tcgaaataca atcttctcga gtatgatctg atcgttacga atcaacccat tttgaatgcc
    32581 catgttcctc atatattgat tgatgatagt gtgtcattcg caaatgaaga agaactcatc
    32641 cgcttattcg agttatgaat aatcaaaaaa cagctatgta taaaccaccc tgataaaaat
    32701 ttcaggacaa atacacatag ctgtttcttt ttattgtatt ccttcagcaa tccaacgaga
    32761 tttatagcga aagtctttta acaactcttc ttttgtccaa ttatttgcaa tgagatccgt
    32821 caaagtgttc attacgaggg tcatggaaaa gtataggaaa ctaactgctt cttccgacga
    32881 ttgaatggag aaatgattga ttcttaataa ttccagccat ttttcgttca ttggagaatc
    32941 agccgatagt tctctacgtt tggttgtctg ctgatcattt cgctgggtta acaagtataa
    33001 cctttgccaa tagatacttt cgtgatctaa gtcgcagcac cactctaaat atttttcgat
    33061 ccccaaaaag aaatgttgtt tgttttcgct aatgaatttt aagatatctt gatggactat
    33121 gtgagaactg cttttgatcg tatacaaata agcatcttcc aaatcttgaa aatatttata
    33181 aaaagcaccg cgcgacatcc ccatcttgtc aacgatttct gagactttga cttggctgat
    33241 gtgctgtgag caaaatatct ccagtaatag gtcatcgatt ctctgtttct ttgcgttcga
    33301 taaattgaaa aaagtttctt ttggcatcca catctctcct ttatctctga ttatacgtgg
    33361 atagcccttc attgtcatga aggattcatt ccttcttttt ctcttcttct gtcaagtacc
    33421 catcttccat tcgataaacg cgatcactcc attgaatcat acggacatca tgagtaacca
    33481 taatagtcgc tttttgtttc tcatgagctt ctttaactag taatttgacg acttcatatg
    33541 catgatctgt atccaaacta gctgttggtt cgtctgctaa gatcaagctt ggctcattat
    33601 ataaagcgcg agcaattgcc actctctgtc tttctccacc agaaaggtct ttaggataac
    33661 tatttttaag tgactggata tctaaagatt gcagcaagga atcgattttt gttgaatctt
    33721 ctttttttga agtaacttgg tcaactagtt caaattgttc ctttaccgtt aaaaaaggaa
    33781 tcaaattaga gctttggaga ataaatccta tttctttaaa gcgtaaatct gctcgttttt
    33841 tttctggaag ctcagttagt gagtgaccgt tgatcactat ttctccggaa gtcggtgttt
    33901 gcaatcctcc tgaaatggta aggaaagtac ttttacctga accagaagga ccaatgatgc
    33961 tgacgaattc tccttccttt acataaaaat caattgcttt caaagctgag acctttgtat
    34021 gaccagaacc aaatgttttg gtaacttttt tcatcgttaa tatttttttc atttttatta
    34081 acctcctatt gctgtaattg ggtctacttt ggttatcgta cgtatcgaaa acaatccgcc
    34141 tagcattgcg acaatgatca aaatcccact atatagcaac cattgtgacc aaaaaacagc
    34201 aaaaggcatc gcgcttggta aaatcagact agtcaaataa gcaaacaaaa gagcaagcag
    34261 aacgcctacc accccaacaa taaaggactg tgctactaaa gatttagcga tgaagaaatt
    34321 tttgatccct tgtgctttca ttactccaaa aatagcagtc ttctgaagtg tcatcacgta
    34381 catgaaaata ccgaccacgg cagcaaccac taagaacaaa aagtatatca tcgcatttaa
    34441 ggtcatattt tgggcagaat agccaggaat actttcaatg aatgtcccaa tagttaataa
    34501 ctgtagaccc ttcgatgctt tttctttcga aattttagct gaatccttta ttacgatccc
    34561 attgatcggc tgttcttctt cagaagcaaa cggctgttgt ccatacttca aagcagtcca
    34621 cgtatctagg gacgcataga tgacgggaga aactgtgtaa taagtttcag gaaagatacc
    34681 gacaatcgtc aaaggatcgt cgtaactgcc aattttgatc gtatctccaa ttttatagcc
    34741 tgaatcagcc agattttgag agatgatgat ttcattcttt gttttaaatt catgcccttt
    34801 cgtgagtttt ggtaataaaa atgcttcttt cgttgtgccg aaaactgtaa cattttcttt
    34861 gttttttcct ttgattgctc cgctgtacaa tccgattggt gctttctctc ctccttcaat
    34921 gtatttcaga tctcctcttg ttaattgtga agctgcaaat acttgatttg catcctccga
    34981 caaaacaatc tcttgtgcgt cccaatcatc gattgctttt ttaaactctt ctgaaagtcc
    35041 attcgctagt cctgacaaca tgaatacgac atacgcaatc aagaacataa taccgacgat
    35101 caagccatat cgtaatttag aatagcgaat ttctttgata gctagaaaca tttgtttttc
    35161 ctccctatga tagattgata gtgacaaaat gtcacttgtt gaatagtgta actctaaagt
    35221 gacaatttgt cacttgtgtt gtttttttct tatcaataaa ttgtctaaga catctttcga
    35281 taaaacctta acatgagtca taaaaaattt atttaagcct tatttatgct ttccatgata
    35341 aactaaagtg accaaatcaa tgaggtggga aaatgattaa actattagta gtagaagacg
    35401 ataaagtatt atccaataat ataaaagaaa tactcgctgc aatcggcgag ataacacaag
    35461 tttatgatgg tagtgaagga ctgttcgagt tggaaagtgg agtttatgat cttgcaatct
    35521 tggatttgat gatgccggaa atgaatggat atgaagtgtt agcaaaaata cggaaagaaa
    35581 aaatacagac tccagtattg attttgactg caaaagatag tttggaagat aagattgaag
    35641 gatttgaacg aggtgcagat gattatctaa caaaaccttt ctatcgagaa gaactgatca
    35701 tgcgcgtgaa agcattattg aaacgctcgc taggtctctt tgatgaaaat gttctgaagt
    35761 ataaggatat cagttgtgat ttaaaaagca atgaagtctt gtataaagaa caagttttgc
    35821 ccatacaagg aaaagagttt gaattgctcg tttatttttt acaaaataag ggaatcattt
    35881 tgacaaaaga gcagatattt gaccggatct ggggatttga ttctgatacg acgattacag
    35941 ttattgaagt ttatatgagc aacttacgaa aacatctgcg aagtactgga ttggataaag
    36001 aaatcaaaac cttacgtaat gtcggttata tactgcaaag ggtgtgatgc aatgaatgga
    36061 gatattacac gaaagcaacg tagtcgcttt tttgcgacaa atgtagcagc atttgctttt
    36121 atcttttttc ttttgggatt cattacttta cagatattaa accaatctgc atacagagaa
    36181 acagatctgt cattagagaa aataaatttt gattctcgaa cagtacaatt agagatacaa
    36241 agatatcagc aaggcgatcc ctttttaaac ccgactcaaa cggaacaaaa cagaacaaac
    36301 atggaacagc cattaatgga accatcaaat gaccgtttta acactcaagt gatcttgtgg
    36361 tctaaaaatg gtgagatatt gaataaagca gctattggtg ggcgtttcaa ccaaatcaaa
    36421 gaattaaaaa tggatacgaa aaatctgaat accatccaaa atattgaatt aaatgaagac
    36481 agtggctcat ctgccctctc tttccgttcg attacgaaaa aagcggagac gaatcaagat
    36541 ggcgttgcct acatccaaat tttagaaaat acaaatcaaa tcaagaattc attagcgact
    36601 tttcgcacga ttatgatttt gtgtatgatt gttttttgga ttctctctat tggtatcagt
    36661 tattacttgt ctagtctaag catgcgccct attattcttt cttggagaag acaaaaagaa
    36721 tttgttgaga atgcttctca tgaattgcgc acaccgttaa cgattattca aaatagtttg
    36781 gaacatcttt ttaccaagcc taatcatact attattgaag aatccgaaag catcgctcaa
    36841 gcattgtcag agacgaggcg cctcactgga ttgacttcgg atttgctgac aatcgctcgg
    36901 aatgattctg atcagcagct gctttcaaag caaatgatca atacacaaga atatatcgaa
    36961 caacttgtta aaccatttca agagatggcc atcatagatg gaaaagagtt tattctccat
    37021 aacgatgcaa cattagaagt accaattgat gaaaaaaaaa tccatcaagt tttggttatt
    37081 ttgctggata atgcattaaa atatacgaat ccagaagata agatcatttt ggattcatct
    37141 gttaaccata aagaatggct gattcacgta aagaatactg gcccttctat cagtgaagaa
    37201 gatcaagcaa ggatttttga tcgattttat cgggaagatc aatctcgggc gaaagagact
    37261 ggcggatacg ggcttggctt ggcaattgca aaacaggtaa tcgaacagca tcatggacag
    37321 atttctgtat ccaattatct tccacaagga gtcgatttta aagtccaatt gccgttgaag
    37381 cctaaaaaat aatgcttatc cctaaaaaag ggctgtgaca aaaatcttgt cacagccctt
    37441 ttttgttgcg aataaacggt gttccagaag tagcttcttc ggaaataagc cgaaatttct
    37501 ttaagctgac cacttctgtc acaacctctt tagcttacgc ttacgatttt ttattgcggt
    37561 cttcaatgtg tacatcaccg cttgtgtcaa tatccaattc ttctcggcta acatcttctg
    37621 tcactttttc aacatcttca tgttcttctt tatgaatccc aacttcttca cgaataactg
    37681 tatgtttgct tacatctact tgctcttctt tgattgggat agtaatcgtg tcatcttcca
    37741 atttttcgtc tgttccctgt gaagattgat ctgttactgg tttgcgttcg atgacgattt
    37801 cttcacgttt gaccggtact tctaccgttt cagtatcgtt gaccacatgt ttgtggatgt
    37861 cgacttctcc agttgtcaca tcatgtgtat ttacatctaa tttttcttct tttagttgaa
    37921 ttgtatcatc atctagattt ggtttgcgat cgatgtcttc agtcttgctt gtacccattg
    37981 tatcagtctc gccaggtacg tccatcggat cagttcctgg tgtcatattc aatggatccg
    38041 ttgtattttg aaagcctgtc gtgccaccta cgtccattgg atctgttcca gtgccagttt
    38101 ctaatccagt ccccattgtg cttgctgggc taacagtatc ttgtgtatcc attgtatctt
    38161 ctgttgtttc tggctgacga tagcctttta ctgtgatgac aaattttcca tcagaaatat
    38221 ctcctctata ttgatataaa ggatcatttt ctggtgtagc cgtctcagaa tcataggtat
    38281 caaaagaaaa agtatctttt attttttccc ataaagaacg gtcttcttca ccatccatcc
    38341 gattttcatc tgtttcaaca tctataccag acaatccgtc aaatcctagt ctagatgctg
    38401 cttcatcagt agtataaata acgatatcat ctcgttcata cccttcgtta cgcaaccgtt
    38461 caattactga taatgcttct tccctcgtac tatagcttcc gatgaccgtt aaatttttct
    38521 cttccatgta aattcctcct agcaaataga tttatgattg gtatattgtt acttataaat
    38581 ttattctata ggagacgatt gttttctaca aatatttaga ttggaatttg attaaaacaa
    38641 tttaattgaa atttgaaaac atttatgtta atgaaagtca tattctaata aaatgtcatt
    38701 tgtttctata tgaattttta tgaaaaattt catataattt ccactcgttg tgatggttta
    38761 atttatccaa tccatcaata agcaaacaac ttatataaaa aaggattaat tctcaatata
    38821 attgctccta ccatagaata aatcttcatg taaagtaatg aagtaccaac tatttctaat
    38881 acttctttaa gaattatccc aacaatatcg ttagacaaac cattattgaa taaatggaga
    38941 gccaatcgat tctgaaaaaa tgttttctaa tttttcggaa ataaaagaaa gagcctcctg
    39001 ccattagaac gaaccaaatc catttcattg ctcatgaagt aaccacatag ctaaaaagag
    39061 gataaatcaa ttaaaagatc aaaagaatga ctgcactaat aaaataacta aaaatgtatc
    39121 ttcttacttc atatctttta gctagtactt agttaaaaat ttgcttccta agatcaagac
    39181 aaactgtcta tcttcatttg atgaaatgcg gtaaaatata gaaaatgaac actattggag
    39241 ggaatttgta atggacagca aaactagaaa acaactgcaa gaaaagttaa agcaacgtac
    39301 acacttgctc ccttccgtct ttcaacagtt tttagaagaa aatcgttctt ccctttcatt
    39361 aggcagtcgc tatgaatacg caaaagattt tcatctgttt actgattatt tgagaaaagt
    39421 attttctgaa gaagtggatg atcagctgat tatccattta gaaaaacaag attatcagaa
    39481 tttcttagct aaaatctatc gacatactcg ttcgttccaa actacagcga accaagaaac
    39541 ggagcaattg tttgaaaata gctattacgg gatttcaagg aagcaatatt cattaaatca
    39601 ttttttacga tttttgtatc aaaaaggact gattgaagaa gagatttctc ttttgggtac
    39661 aagtttaccg gaaacaacca aagcagctcc gcgatatatc gatgcagaac ttttcaaaga
    39721 ttttgagcat ttgtttatcc cgattgaagg ctttcaaaca agcagagaag ctagctttga
    39781 agaaaagaat agaccgagga accttgcaat tactgccatt cttctgtatt gcggattaaa
    39841 gatccatgaa gtagtagaac ttaaacgtaa agatgtatct ttgaccaagc agattcttaa
    39901 tctgaataga aaagaaaaca gactgaataa agtaccaata ccaaaagaag cgatgccatt
    39961 tctggagaac tattttaagt taacagcaca aaatacggac gaaaattctt ttgtttttcg
    40021 ttcctcacat gatcagcaaa tttctcctcg gactattcgc caaattttga gcaaaattac
    40081 agtatataaa aacgtatcgc cagaactatg cagaaaaaca tatcgttatt atgcagaact
    40141 atatttagat gatgctgacg cggtaaatta tttatgtggt aatcgatacc tctcatccca
    40201 ttcttttcaa gatatctggg aaaagatggt tgatttttct tatcacgaat tagcggcatt
    40261 cgttcgggtt tcttccatat aaaacaaatg tatgatcttt ttttcacaat aaactatgtt
    40321 attatataaa ggattatgtt acgattatct tgaatttgta tattacttaa caaaagataa
    40381 tggagtgtga atgatggaga ccataacgta ttcccctttg aacttattta cgaattttca
    40441 agaagctgca gctaactttt ccgagacccc gattatcttt gatgagccac tttcagcttt
    40501 cccagaatta ggacttgaaa caacttacaa aaaatgctgc gaaagtgtgt tgaaacgggc
    40561 ttatcaattg gctcatcttg gagtgaaatc cggagacaaa gttattattt ataagagttc
    40621 cgcttttgac acataccttc tagctgtttc tgtgtcttac cttggtgcag tgcctgtcat
    40681 gacttcttat catctaccaa caacaacaat ggaagtattt atcgatcgtt tagaagaccc
    40741 tttcatttta tttgatgatg agacaaaaaa gcgagtgaga gaaatttcaa atggaacaaa
    40801 atcaaaacag attcctattc tttatttaat ggaacaacct gctttgtctg tttctcaatc
    40861 atttttagac aaaaatgaaa tttcttatat gacccatact tctggtacaa ctggtatccc
    40921 taaacttatt tgtcattctg ctcattctat gggatggcgg acgaaatggc aaaaaacagt
    40981 tttcacaaaa atttcggaaa agaaattaat cgcttttcac atctctccag tgcattccag
    41041 attcaatatt ggtatctctt ctttgatgtc catgggattt cctatgatgc ctttagcaaa
    41101 cgcacaaagt tcaaaagttg ttcatatgtt ggaagctcac cggccaattg cactagagac
    41161 ccatccgaat aactttgttc agtggcgttt tactgctaag gagcatccag aagctttttc
    41221 gggtatccga tactatcact ccacttttga tgctataaac aaccagacaa tgaagacatt
    41281 tttgcgaacg tcgatggcac aggatgcggt atttcttcaa gtatatggcc aaagtgaatg
    41341 cggaccaatg attcttaagg ctcatacact agagagtttg aaaacaagtg atgcaagaga
    41401 tatgggcgtt ggactggaag acatgacaag cgctcggatt acagattcag ttgggaatgt
    41461 cctacctgaa aacacagatg gtcatataca attactgtct aaaggacggg ctttgactta
    41521 ttacaaggaa gatgcacggt tccaggaaaa tgtttatggc gattggtggg atagcggaga
    41581 ttacggtttt atggataagc atggccacct atttttgaaa gatcggcaag tggatttgat
    41641 cgaaacgatc aatagtacat tagctattga agacttttta ttagattcgt tagatttttt
    41701 ggcagaagta gtgattgtaa gggataaaaa tcattctcca caaccgatta ttgctttagc
    41761 tcctgataaa gaaatggatt ggaatcgatg gtgggagcaa gtccatgaac ttcctcgctt
    41821 gaacgtccct atcatccgtg attttgatgc aatcccgcga acagctacaa tgaaagtgca
    41881 acggcttcaa atcgagaaag aattaaaatc acaaaagtcc taactattta aggaaagaaa
    41941 gatccatttt ggtctttctt ttctttttgt ttttttaaat tggatgagat aaaaatatgc
    42001 caattggctg tttttctttt ttgaaaattt cgttatactc ttattcatgg aggaaaatgt
    42061 tatgaaaaga atcttgacaa ttggcggttc tgatccattt gctggtggag gaatccaaac
    42121 agatttaaaa acttttgaga attttggtct attcggacta agcgccttga cttctatagg
    42181 ggcactagat attaatgagc gatttatgct ggaatctata tctttggaat tgcttaaacg
    42241 acagttagtt tcgattgata aaatgacttc attagatggt atcaaaattg ggttattgaa
    42301 ttcaagtgaa gcaatcatgg ttgttcgaga cttcataaaa acaaaacaaa atatcccaat
    42361 cattttagac cctgttttgg cattcaaaga aactgaagct gtgatcaatc aattgtatat
    42421 ttcgcagctc atcgaagaac tttttccact tgttacgatg attacgccta atttggcaga
    42481 agctgcttta ctttctggtc aagctcttcc ctcttcgtta acagaaatga tccatctcgc
    42541 taaagaactc actgcttcag gaacaaaaaa cattgtgatc aaaggcggca caaggatggc
    42601 tggagatgaa gctgtggatc ttctctattc aattgatcat tatgaggtat tttctcataa
    42661 aaaaatcgac actacaacag taaacggggc cggttgtgcc ttttcttctg caataacagc
    42721 gaatcttgtg ttaggggcag attttaccaa agcagtagca gaaagtaaaa aatttgttgc
    42781 ccattgtatt tctaatggcg tgctgatgaa cgatcatacc ggaagtgtct ggtctggcgg
    42841 tattcaaaaa ggaggaatga gaaatgaaaa ctaagcaatt aacgatctat gctatgctga
    42901 ttgcgttgac agttgccctt tcattaacaa ttttgatccc tgtaccggct acgaatggat
    42961 ttgtgacatt atgcgaggcc gggatctata ccgctgcttt tctttatggt ccaacgggtg
    43021 gattagttgt tggtgcttcc agtggtctat tgatcgattt gatttcagga tatccgcagt
    43081 gggcagtttt ttcattagtg atccacgggt tacaaggata tgttgctggt tctttcagca
    43141 aatcttctac tcgtatgtgg ggattagggc ttttattagg aagcttagtt atgatcatcg
    43201 gctatggtat cgccggttgg attttatatg attggccggc tggagtggct tctataccag
    43261 gaaacatctt ccaaaatctg attggaatgg gacttgcctt tcctataact gcaagtcttc
    43321 aacgtattca agcacggaag caatattaat tgaaaaagaa ggttttagaa aatgaagttg
    43381 tcagaaaaag aattaaaaga ccaattgact gaaatagtta atgacatatt ggctgaggca
    43441 cacttgaaaa aaggtgatct ttttgtttta ggatgcagca caagcgaagt cgttggagga
    43501 catattggaa aaaattccag tgcggaagtt ggtcaatgga tcatccgtac gttaaaagag
    43561 ttgttggatc ctaaagaaat tgcgctagct gtccaaggtt gtgaacattt gaaccgagca
    43621 ttagtagtag aacgaacagt ggcagaagca aaaaatttcg aaattgtctc tgttgttcct
    43681 gcactacatg ctggaggtgc ttgttctgtt gctgcttttg accagttcaa tgatcctgtc
    43741 gaagtggaac acgtagttgg acaagccggt atcgatatcg gtgacacatc aatcggtatg
    43801 catatcaagc atgtccaagt acctgtcaga cctcgtttga aaacccttgg acaagctcac
    43861 gtgacagccc ttcgctctcg tcctaaatat atcggtggtc ctagagcgaa ttattgaaat
    43921 gagtaattga cagagcaatc tgaaaaactt cctcgcaaag tccaactaat gaactttaac
    43981 gaggaagttt tacttgtttg ttttatataa ccgagcttca taaggtgcta gtatgccttt
    44041 agcttcaaat tctccgctag aggaatttga caagagtaat gtccaggact gatctgcttc
    44101 ttttggaagt tcatagtcag caagtgattc tgttaagttt accataataa gatattgttc
    44161 atcttctaaa tatctttcat agacataaag ttgtggatgt tcatgaagat attctttata
    44221 agaaccgtat atcagacctt tattggtttg tctaatgcgg atcatgttct tatagaattg
    44281 caggaccgac tctggttcat attcttgttg ttctacattg atcgttttgg tatttggatt
    44341 agtgatcagc caaggttcat gtgtagaaaa accagcatat tgttccgaag tccattgcat
    44401 gggtgtcctg ctgttgtctc tcgttgtttc acgaatgata tccaatgctt cttctcttgt
    44461 cttaccttcc gcaagcagcc ttttataaag tcttttcgaa tctactgcat caacttgatc
    44521 gatcgattca aagggcatat tcgtcattcc gatttcctgt ccttgataaa taaatggcgt
    44581 accttgcaaa aagaaataca tcatagcgat tgcttttgca gacatagccc aaaaatcggg
    44641 acgagtatct ccaaacactg aaacggcacg aggaacatca tggttttcca tatataaagc
    44701 gttccatccg ataccatcca atgaagtttg ccaagcgctt aatgcatgtt tcaatttaag
    44761 gacatctaat tgcccttctt tttcttgctg ccagatatgg atatgatcaa attcgaatat
    44821 catatcgaaa taaccgtctt tccctaccca ttgtggtcct tcttctgcag tgacaccact
    44881 tgcttctccg acagtcatga tatcgtactc ttcaaaaaca tgtttcaaat cggtcaaatg
    44941 ttcttcgatt cctgagacat tttgaaaggg tgagaaaggg ttctctgtgg cttttactga
    45001 atattcatct ttttttacat gagaaatcgc atctaaacga aatccatcta tccctttatc
    45061 caaccaccat cggatcatat tgaatagttc ttctttcaat ttctcgcttt cccaatttaa
    45121 gtctggttgt tcttttgcaa aaacatgcag ataatactgt ccagtttcat gagaatactc
    45181 ccaagcagaa ccgccgaaaa tcgatgtcca attattcggt tctttgccat ctaccccgtc
    45241 gacccaaatg taataatcgc gatacgggct ttctttagat tttttcgatt cttcaaacca
    45301 ttgatgctga tccgaactat ggttgatgac aagatccata atcactttga tccctaattc
    45361 atgtgcttct tttagcaata aatcaaaatc ttccatcgtt ccgaatctct cttctatatc
    45421 ttgatagtca cttacgtcat aaccattatc gacaaatgga gattgataga tcggattgat
    45481 ccagataaag ccgataccaa gatctttcaa ataattaagt ttttcacgga tcccattgat
    45541 gtctccttga ccatcgccat tgctatcttt gaaactagca ggatagattt gatagcctac
    45601 tgcttctttc caccattttt gttcttgtat catatcgttt cactccttta acggtccctc
    45661 ttgattataa ccgattctat tttagaagta tccttgttac cggtaactag aaacgaaaag
    45721 ctcaacgaat ctgctaagtg cgttcgttga gctttatttt atcatagata gcgggcaatc
    45781 agttgaatca tttgcttggg aaattcattc aagtcagtaa tatctacaaa acgactttca
    45841 ccgtagatcg acttgatttc ttctttgtct tggccaatag ctgcggagac aaataggatt
    45901 ccttgacgtt catattcttt caaaacagac tggatatctt cttttgcttt tttgcctgta
    45961 taatccggca acgcttttgg ctgaccgtca ctaatattaa gcaacagttt ggttgttgcg
    46021 gattgtctgt ttaatttttc tgctgctaaa cgaagtgcag caccatcacg attgttttgc
    46081 cttggtttca tagtgactaa tttttcattt aaccattgaa atccgtcttc aaattcttta
    46141 taagaaaaca aagaagtctt ttctcttgac gaacggtctg ctgtatctcc gtaaatcaac
    46201 aatgggatat cgactttctt agaaaattcg gcaatggcaa tcgctgcttt ttttgccgct
    46261 tcgatccgat catcccgtat cattgaccca gattcatcga tccgtacagc taccgctaaa
    46321 gaaggttgct catgtggcgg gttctttttg tcaaaatttc tcaaatcacc atatgctact
    46381 ttgcttgcat tgaaccgctg accttcgtat tttccttttt ggtacgtctc tgtttgttca
    46441 ttatccagta actctaaaat ttgccggcta agtgattcta ctattggcat tacttgcatg
    46501 tgtagctcac gtgcttccgg cgtttttcct tggaaagctg gtcggtgaac gatgagacct
    46561 tctttttcat gaatcgtttc cttcatgatt tgtcgcgctt ctttattcag ttgcttcttg
    46621 atttccttat catgtgcttc catgtcagaa gcagacattt cttgagaatc atctcctgtt
    46681 tgttgttctt tttgattttt tccttcgata tcgctactgc gttctttttg catttgagga
    46741 ggaatctcgt ttttttctat tgtttcttct tgtttctctt ctccctcatt tggttcttca
    46801 gcagacaacg atttcttttc atctaagcgc agaatttctt cagcattttc agtgatgttt
    46861 cgttcatttg cttcttcggc gctaatggtt ctttcttttg tatgctcaga ttgaggatga
    46921 ccccattttt cttttctcaa tatgtcctga agttccagta gcaatccact gtcagacaaa
    46981 gcttgttcaa gaattgccaa ttcatctgaa tcagtggata atttatacaa aacttttgga
    47041 taaatcgact ggagtaaatc ttgtccttgc ttataggtat ttgcccaata aaaataagaa
    47101 cgcattcctg ctacaccttt gatggcgtta gcttttgcag tttcatccaa caaacggata
    47161 atctctgcca tctttaagag aagttcttgt ttttggatca tagttttcgc catcgcacgt
    47221 tctgccatga cttctaaggc aggaagatcc attttttccg catgttgcat ccgatctctt
    47281 aaagattcat ttaatgggcg atttccttgg taatttcgat ttgtagtgat cacaatgacg
    47341 caatctggat ggcgacgaat gattcctgtc ggtaaattca acatcccatt tggttcgagc
    47401 gctgagttaa gtgccacaag aacagaggca tctcggatga cagtcggctc ttgaatctct
    47461 aataaatagc ctttttcaat cgctcgaacg atttcagaag ggtaatagct gtaatggatt
    47521 gcatctggat aatcagcttc gatcctttga actagctctg ctaatttttc tttagcagaa
    47581 aaaggatcaa tgccgtaatg gttctggatc agtgtcagta cagcttcaag tgtatctgtt
    47641 tggtaaatag cttctagtaa ttcttggtct tgttccttat tagaatctac tacaggtaat
    47701 aaggctccga aaacatctga tttgtccata tctgcaaaac aggtcacttt tgtataggga
    47761 agttgcagat cagcagatag tgctttggct aattgtgtct tccccgaccc ggcatctcct
    47821 tccaaaagta cgttactgat tttcatttca ggatcttgcc aattcccttt gatttcggag
    47881 gcgatccgcc attcttctgc acttgtccga tggcttttcg gtttcttcca gatcatttgc
    47941 ttttctagcc gtgaaaaggt tcggttttct gttagtgaga aattctccat gcttctcttc
    48001 cccttttgat catctctgtc tattaatatc ctagctcatc taaaagacgt tttaaaatac
    48061 ggaatcgttc cccaatcagt tctccgtctt tttgtagtgt atcgtaatac aaaatgatgt
    48121 cttcatcgat ctttggattt ttggtatcta cttctaccgt cattcggttc ccttgtaatc
    48181 caatgatgtc tacgactgga ttttctggat cataaaattt ttcataacga taagcatctt
    48241 ggaagtataa acttccttgc gcagctaaga tcgctaaatc taaaatacgt gtgattggta
    48301 attcttccga ctgtcgtgac catttttctc cagtatgtcg ccataccttg cctgagatat
    48361 cgacttttcc acgatcattc cactgagcaa ggcccagtga aagccctttt gcatccatat
    48421 ttaatgcatt tcttccatca actttatcat agtcttctac aacgattact ggtttatgtt
    48481 ttaaatttgt tggtatttcc attattttaa ctcctcatcc ttttattttt agtaaataag
    48541 taaattagta gtttactcat ttactaaact atatgcgaca ttatagagga ttgaagtgag
    48601 gattgcaaag aaaaagagct tcattgatag aaataaaaac accatctcgt tcttttacac
    48661 gctcattagt aacatgtaga aagtccaaga tgatgttgga atattttggc tctatacttt
    48721 ttgatgttgg tgaacttcac caacatcttt tttgtattct taattgtcaa attaagttag
    48781 acagatcatc aatacttacg taactcaaaa atacttccaa agg
//
LOCUS       DAFENC010000019        48482 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.019, whole genome shotgun sequence.
ACCESSION   DAFENC010000019
VERSION     DAFENC010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 48482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48482
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.019"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(29..376)
                     /gene="rbfA"
                     /locus_tag="LP493_001378"
     CDS             complement(29..376)
                     /gene="rbfA"
                     /locus_tag="LP493_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HBL2133537.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(403..2709)
                     /gene="infB"
                     /locus_tag="LP493_001379"
     CDS             complement(403..2709)
                     /gene="infB"
                     /locus_tag="LP493_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HBL2133538.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(2722..3033)
                     /locus_tag="LP493_001380"
     CDS             complement(2722..3033)
                     /locus_tag="LP493_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HBL2133539.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(3030..3323)
                     /locus_tag="LP493_001381"
     CDS             complement(3030..3323)
                     /locus_tag="LP493_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HBL2133540.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(3345..4520)
                     /gene="nusA"
                     /locus_tag="LP493_001382"
     CDS             complement(3345..4520)
                     /gene="nusA"
                     /locus_tag="LP493_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HBL2133541.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(4543..5016)
                     /gene="rimP"
                     /locus_tag="LP493_001383"
     CDS             complement(4543..5016)
                     /gene="rimP"
                     /locus_tag="LP493_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HBL2133542.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(5161..9519)
                     /locus_tag="LP493_001384"
     CDS             complement(5161..9519)
                     /locus_tag="LP493_001384"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HBL2133543.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            complement(9731..11440)
                     /locus_tag="LP493_001385"
     CDS             complement(9731..11440)
                     /locus_tag="LP493_001385"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBL2133544.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTNLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELVNTLPILLN
                     QGE"
     gene            complement(11508..12776)
                     /gene="rseP"
                     /locus_tag="LP493_001386"
     CDS             complement(11508..12776)
                     /gene="rseP"
                     /locus_tag="LP493_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HBL2133545.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAILLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPDKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(12937..13737)
                     /locus_tag="LP493_001387"
     CDS             complement(12937..13737)
                     /locus_tag="LP493_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBL2133546.1"
                     /translation="MKQRVVTAAVALVLFIPIIWIGGIAVELTAAILAVIGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(13734..14546)
                     /locus_tag="LP493_001388"
     CDS             complement(13734..14546)
                     /locus_tag="LP493_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HBL2133547.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(14741..15298)
                     /gene="frr"
                     /locus_tag="LP493_001389"
     CDS             complement(14741..15298)
                     /gene="frr"
                     /locus_tag="LP493_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HBL2133548.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(15301..16023)
                     /locus_tag="LP493_001390"
     CDS             complement(15301..16023)
                     /locus_tag="LP493_001390"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HBL2133549.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(16159..17040)
                     /locus_tag="LP493_001391"
     CDS             complement(16159..17040)
                     /locus_tag="LP493_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HBL2133550.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(17139..17921)
                     /gene="rpsB"
                     /locus_tag="LP493_001392"
     CDS             complement(17139..17921)
                     /gene="rpsB"
                     /locus_tag="LP493_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HBL2133551.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            18280..18759
                     /locus_tag="LP493_001393"
     CDS             18280..18759
                     /locus_tag="LP493_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HBL2133552.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            18976..20067
                     /gene="phnW"
                     /locus_tag="LP493_001394"
     CDS             18976..20067
                     /gene="phnW"
                     /locus_tag="LP493_001394"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HBL2133553.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            20060..20188
                     /locus_tag="LP493_001395"
     CDS             20060..20188
                     /locus_tag="LP493_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBL2133554.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            20192..20737
                     /locus_tag="LP493_001396"
     CDS             20192..20737
                     /locus_tag="LP493_001396"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBL2133555.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(21191..22882)
                     /locus_tag="LP493_001397"
     CDS             complement(21191..22882)
                     /locus_tag="LP493_001397"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HBL2133556.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(23302..24249)
                     /gene="arcC"
                     /locus_tag="LP493_001398"
     CDS             complement(23302..24249)
                     /gene="arcC"
                     /locus_tag="LP493_001398"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HBL2133557.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(24364..25383)
                     /gene="argF"
                     /locus_tag="LP493_001399"
     CDS             complement(24364..25383)
                     /gene="argF"
                     /locus_tag="LP493_001399"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBL2133558.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(25474..26703)
                     /gene="arcA"
                     /locus_tag="LP493_001400"
     CDS             complement(25474..26703)
                     /gene="arcA"
                     /locus_tag="LP493_001400"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HBL2133559.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            27164..27865
                     /locus_tag="LP493_001401"
     CDS             27164..27865
                     /locus_tag="LP493_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBL2133560.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(28474..29490)
                     /gene="tsaD"
                     /locus_tag="LP493_001402"
     CDS             complement(28474..29490)
                     /gene="tsaD"
                     /locus_tag="LP493_001402"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HBL2133561.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALAAKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(29487..29951)
                     /gene="rimI"
                     /locus_tag="LP493_001403"
     CDS             complement(29487..29951)
                     /gene="rimI"
                     /locus_tag="LP493_001403"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBL2133562.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(29958..30500)
                     /gene="rimI"
                     /locus_tag="LP493_001404"
     CDS             complement(29958..30500)
                     /gene="rimI"
                     /locus_tag="LP493_001404"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBL2133563.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(30484..31206)
                     /gene="tsaB"
                     /locus_tag="LP493_001405"
     CDS             complement(30484..31206)
                     /gene="tsaB"
                     /locus_tag="LP493_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HBL2133564.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(31397..32377)
                     /locus_tag="LP493_001406"
     CDS             complement(31397..32377)
                     /locus_tag="LP493_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2133565.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(32401..33885)
                     /gene="galT"
                     /locus_tag="LP493_001407"
     CDS             complement(32401..33885)
                     /gene="galT"
                     /locus_tag="LP493_001407"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HBL2133566.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(33897..34886)
                     /gene="galE"
                     /locus_tag="LP493_001408"
     CDS             complement(33897..34886)
                     /gene="galE"
                     /locus_tag="LP493_001408"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HBL2133567.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            35134..35301
                     /locus_tag="LP493_001409"
     CDS             35134..35301
                     /locus_tag="LP493_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HBL2133568.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(35363..37174)
                     /locus_tag="LP493_001410"
     CDS             complement(35363..37174)
                     /locus_tag="LP493_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HBL2133569.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(37171..37536)
                     /locus_tag="LP493_001411"
     CDS             complement(37171..37536)
                     /locus_tag="LP493_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HBL2133570.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(37699..38094)
                     /locus_tag="LP493_001412"
     CDS             complement(37699..38094)
                     /locus_tag="LP493_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBL2133571.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(38112..39074)
                     /locus_tag="LP493_001413"
     CDS             complement(38112..39074)
                     /locus_tag="LP493_001413"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HBL2133572.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(39074..39286)
                     /locus_tag="LP493_001414"
     CDS             complement(39074..39286)
                     /locus_tag="LP493_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HBL2133573.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(39307..40005)
                     /locus_tag="LP493_001415"
     CDS             complement(39307..40005)
                     /locus_tag="LP493_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HBL2133574.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(40025..40567)
                     /locus_tag="LP493_001416"
     CDS             complement(40025..40567)
                     /locus_tag="LP493_001416"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HBL2133575.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(40699..41703)
                     /locus_tag="LP493_001417"
     CDS             complement(40699..41703)
                     /locus_tag="LP493_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBL2133576.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(41700..42689)
                     /locus_tag="LP493_001418"
     CDS             complement(41700..42689)
                     /locus_tag="LP493_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBL2133577.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVEKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(42686..43492)
                     /locus_tag="LP493_001419"
     CDS             complement(42686..43492)
                     /locus_tag="LP493_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2133578.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            43658..44614
                     /locus_tag="LP493_001420"
     CDS             43658..44614
                     /locus_tag="LP493_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL2133579.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(44691..45209)
                     /locus_tag="LP493_001421"
     CDS             complement(44691..45209)
                     /locus_tag="LP493_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBL2133580.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(45297..45446)
                     /gene="rpmG"
                     /locus_tag="LP493_001422"
     CDS             complement(45297..45446)
                     /gene="rpmG"
                     /locus_tag="LP493_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBL2133581.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            45674..46120
                     /locus_tag="LP493_001423"
     CDS             45674..46120
                     /locus_tag="LP493_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBL2133582.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(46315..48210)
                     /gene="asnB"
                     /locus_tag="LP493_001424"
     CDS             complement(46315..48210)
                     /gene="asnB"
                     /locus_tag="LP493_001424"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBL2133583.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
BASE COUNT        13668 a        10349 c         8502 g        15963 t
ORIGIN      
        1 atttcacagg atttgcggga gtttttgatt agtctttgtt caagtcgcga agcaattcat
       61 cgatatggtt gccatagaca actgattcat caagttcaaa gaacaattca ggtgtcttat
      121 aaatacttag attgtgccct aactctcgac gaatcaatcc tgatgcttta ttcaatccat
      181 cttgtgctgt tttcttatct gatgctaagt cagataaaat gctgtaatag atcgttgctt
      241 gctgtaagtc ccccgtaact ttcacatctg tgatcgttac gttctccaca cgagggtcac
      301 ggaccttttt gcgcaaaata tcattgactt cttttaagat ttcttgaccg actcggcggt
      361 cacggtagtt agccataatg attggcctcc ttttatcagt ttttagtcat ttttgacttc
      421 ttccatgata aatccttcaa ttacgtcatc tactttgatg tcattgaatt tttcaatcat
      481 tgcaccacat tcataaccca ttttgacttc tttcacgtca tctttgaatc gtttcagact
      541 tgcaagttgg ccttcataga ttacgattcc gtcacggatt acacggacac cgctatctct
      601 acgaatatat ccttctgtta cataggcacc tgcaatcgta ccaactttag aaactttgaa
      661 ggtttcacga acgatcattt gaccggtgat tttttcttca aattcagggt ctagcatccc
      721 tttcatcgca gtttcgattt cttcgatggc tttatagatg atacggtgaa gacgaatatc
      781 gacttcttca gtatcagctt gcacttttgc ctgcggtgta ggacgaacgt tgaaaccgat
      841 gataatagcg ttgctggctg ctgctaaggt tacatcactt tcattgattg ctccgacagc
      901 tgaatggacg atttttacac ggacaccttc cacatcaatc ttcttcaatg atgcagccag
      961 tgcttctgct gaaccttgta catctgcttt gatgattacg ttaacttctt tcaattcgcc
     1021 ttctttcagg ctttcaaata agttatccaa agtcacacgg cttgtggcag cacggttttc
     1081 taataatgca cgtttcgcgc gttcttcacc cgctgcacgt gctgtctttt cgtcttcgaa
     1141 gactacgaaa cggtcacctg cttgaggtac atcattcaag ccagtgattt ctactggcgt
     1201 tgcaggtcct gcttctttat cgcgacggcc aagatcgttt gtcattacac ggacacgtcc
     1261 gtaagtatta ccgacaacga ttgggtcacc aacatgaagt gttccttctt ggacaagtaa
     1321 ggttgacaca ggacctttac ctttatcaag acgtgcttcg atcactgttc cgattgcgcg
     1381 ttgtgttgga tctgctttta aatcttctac ttctgcgact aacaggatca tttccagcaa
     1441 ttcttcgatg ttttggccga atttcgctga gatctcaaca aagatcgttt ctccacccca
     1501 tgcttcagga attaactcat actcacttaa ttcttgcata acatgttgag ggtttgcacc
     1561 tggtttatca attttattta cagcgacgat gattggaacg cctgcagctt tggcatggtt
     1621 gattgcttca actgtttgtg gcatgacgcc atcatctgca gcaacaacta agatcgtgat
     1681 atctgtgata cttgctccac gtgcacgcat acttgtaaag gccgcatgtc ctggtgtatc
     1741 caagaaagtg attggtttac catcaatatc gatctggtag gcaccgatat gctgtgtgat
     1801 tccgccggct tcgccgcttg ttacacgtga atggcgtaat gtatccaata aagttgtttt
     1861 cccatggtct acgtgtccca taatcgttac gactggcgga cgtgagacta atttatctgg
     1921 atcgacttct tctgcctcga agaatttatc gatatcagca atgtcaactt ggactttttc
     1981 ttgtggttcc atgccatagt ccgtcgctaa cagttcaatc gtatctttat ccagtgcttg
     2041 gttttgattg accatgacac caagcataaa taatttttta atgatttctg ctggctcacg
     2101 atgaattttt ttcgcaatat ctgctacgtt cataccttca gtatactcta atacatctgg
     2161 caattcacgg aatttgcgtg gtggtacagc tggtttagtt gattgttgct gtttgccttt
     2221 tttacctttt ttattataac gattacggtt attattatta aatttgccgc gattgttatt
     2281 gtttggtttg ttgttattgt tagtacggtt ttgattgccg ccttggctcg ttccttgacg
     2341 attttggctg ctggtatttc ccgtattatt ttggtttgtt gttggttttt ttccttgatt
     2401 cacttgaccg ctcccttgac cgcgatcttg ataactgcgg ttatttttat ttttttgttg
     2461 attgttcgtt gtttcttttt tacgttgatc gttcggctgt tgattggctg gttttctgct
     2521 tgcttgttgt gcagcttgtt gtttcgtgct tgggtttttg aacgcttgtt gcaatttctt
     2581 ctcatcattg ctagtaatcg cacccatatg gtttttcaca tcgatgccaa gttgttgtgc
     2641 tttttccacg acgtctttac tagatttttt gagttctttt gctaattcat agattctttt
     2701 gttgcccatg caatcacctt cctaaccttc aattagctcc ttggtcttct tcgcaaatcc
     2761 ggcatccatt attccgaata ccttgcgagg ttttccgatc atctgcgtga tttctgcttc
     2821 agaaaatagc tcaaagcaag gaacttcata atatgaactc ttatctttta tcttttttct
     2881 tgtattctcg cttgcatcgg ttgccacaaa caccaatttt gctttttgtt tgcggatttc
     2941 agcaatggtc agttcttcac ccgtgattag ttttcccgcg cgcatcgcta gaccgatgag
     3001 attcatggct ttttgccgat taactgtatt cattttccaa ataactcttt acgtgctttt
     3061 tggtgagtga catagtcaag aagttcttga taaaactcat ctgttaatgt tgtttcgagt
     3121 actcgatcga gaattttttt atcccaagct tgttgtactt cttccggctc aagtgagaca
     3181 tacgctcctc gtccaggcat ttttccagtt ggatcgatcg atacttcccc ttcttttgaa
     3241 cgggtgattc ggaccatctc ttttttaggt ttcatttcac ctgaaaccac ggatttgcgt
     3301 aaaggaattt tcctttgttt catctctttg cctccttact aaagttaagc ttctggtttt
     3361 tcttcgaccg tttcattgtt gaatgcaatt gtttcatatt catcgtctgt taaatctgac
     3421 tgaacgattg cttcatcatg cagttcttct gtttcttttt gttgttcttg attttcataa
     3481 aattccgtca tgtcagattc tgatttgata tcgattttat ggttagtcaa tttagcagct
     3541 aaacgtgcgt tttgtccgcg tttaccgatt gctagcgata attggtagtc tggaacgaca
     3601 actgtgcagg cctttggatt tgtctcatcg aagatcacat ccatgacttg tgcaggattc
     3661 aatgcatttg caatgaatac agctggatct tcattccatt cgacgatatc catgttttcg
     3721 ccttttaatt cattgacgat tgcttgaact cgttgtccct ttggcccgac acatgtaccg
     3781 actgcatcga tatttggatc atttgagcga actgccactt ttgaacgatc gccagcttca
     3841 cgggcgatgc tgacaatttc aacgattcca tcatagactt ctggtacttc ttgctcaaat
     3901 aagcggcgca ataggtctgg atggctgcgg ctaacaaata cttgcggacc tttagacgta
     3961 ttttctactc gggaaacata aactttgatt cgatcatgtg gttgataaaa ttcatttggc
     4021 atttgatctt gtttagaaag aactgcctca attttaccaa gattgacata aatataacgt
     4081 ttatcctggc gttcgacgat tccttgcatg atgtcttttt cataagcact gaattcgtta
     4141 taaataatcg ttctttctgc ttcacgtaca cgctgtaaaa taacttgttt agccgtttgc
     4201 gcagcgatcc gcccaaaatc ttttggtgtt acttcaaaac ggatcgtatc accgatctca
     4261 tatgctggat tgattaaaag tgcatctttc aatgagactt ccaactgtga atccatcact
     4321 tcttccgtta cttcttttac cgcatagaca tggatctttc cttttttctg atcaaattcc
     4381 acttcgacgt tttgtgcttg gccatagtga cgtttgtatg cagaaaccaa tgctgcttct
     4441 aaagcatcga tcacgatttc ttttgagatc cctttttcag cttctaaagc gtctaacgca
     4501 tttaacattt ctttactcat tttttctgat tcctctccgt gattaaaatt ggatagctaa
     4561 gcgagctttt gcaatatttt ttcggtcaaa agtcaattct ttttctcgtg tttttatgcg
     4621 tattttcaat gtaagctgtt cagcatcaaa tgattgaaga aatccttcat attgtttttc
     4681 gccatctact ggttggtata aggagacatg gacataatca ccaagtgcct tttcatagtc
     4741 gctttctttt ttcaatggcc gctctgctcc cggggaggat acctccagga aataagcttg
     4801 aggaatcgga tctggatctg ctgcatcaag tttttcactc agtttctcac tgacaaaggc
     4861 gcattcttcg atatcgatac cgccttcttt gtcaataaat actcgtaaga accagctttt
     4921 tccttctttt acaaattcga cttcgacaag ttcaaaattt tgttcatcta aaatcggtgt
     4981 caccatttct gtgactgttt caacgacgct actcaaaagt ttcgcctcct taaaaaatta
     5041 agtgcgtaat tccattaaaa agagtgagcg aaaaatccgc tcactcacag ttagtatcat
     5101 tacctataag aactatacca tactctgctt aaaattacaa gcagacagga aaacagatgc
     5161 ttatagcata tcgaataacg ataattgatt ttcatctggt agatctttca atacgccatt
     5221 gtcgttcata tattcgatca atgtttttga aactttaccg cgggtggcaa gatcttcttt
     5281 ggataaaaat ggaccgtctt ttcttgcttc aacgatttgt tttgccacgt tggttcccaa
     5341 acttgggaca gctctaaatg gtgcgatcaa cgtatcacct tcaataacaa agttaacggc
     5401 atccgattta tacaaatcaa tcattccaaa tttgaatcct cgttccagca tttcattggc
     5461 taactccagc actgtcagtt gattcttttc ttttacggaa gcatctaatc ctttgtccgt
     5521 gatttctttc attgcttgtt tcacagcatc ttttcctttg cacatggaga ctagatcaaa
     5581 gtcgtctgca cgtacagaaa agtatgcaca gtaatacaaa atagggaaat aaaccttgaa
     5641 ataagcgaca cgaagagcca tcaatacgta agctgcagca tgggctttcg gaaacatata
     5701 tttgattttt gaacaagaat cgatatacca gtcgggcaca ttattttctt tcatcgccga
     5761 tagataggtt tctcgcaatt catcagggat cttgttccat tgtcctttac gaacagtttc
     5821 catgatttta aatgccatcc cgctatctaa tccagcatgg atcaaataaa ccataatatc
     5881 atcacgacag ccgattactt ccgccagtgt cgcatctcct cgtcgaatca attcttccgc
     5941 atttcctaac catacgtctg taccatgaga tagtccggaa atttgcagta gttctgcaaa
     6001 agttgtagga tgcgtttctt ctagcatccc tcgaacaaaa cgagtgccga attctggaat
     6061 acctaatgtc cctgttttgg aataaatttg ttcctgactt actccaagta cttcaggacc
     6121 ggcaaatatc cgcatcactt ccgggtcatc cgtagggatc gtttgtggat cgatccctga
     6181 taaatcttga agcatccgaa taacagttgg gtcatcatgc cctagaatat ctaatttcaa
     6241 tacattatcg tgaatcgagt gaaaatcaaa atgagtcgtt ttccattccg aattttgatc
     6301 gtctgctgga tattggatcg gcgtaaaatc atagacatcc atataatcgg gaataacgat
     6361 gatcccccct ggatgctggc cggttgtccg tttgactcca gtagcgcctt ttgctaatct
     6421 gtcgacttct gcacttcgaa actgcagatt attgtccctt tcgtatcctt ttacatagcc
     6481 atatgctgtt ttgtcggcga ctgtaccaat cgttccggca cggtaaacat agtcttcgcc
     6541 aaacaatact ttcgtatagt tatgggcttc tgcttgataa tcacctgaga agttcaaatc
     6601 aatatcgggc actttgtctc catggaatcc taaaaatgtc tcaaatggaa tatcatgacc
     6661 gtctttgttt aagcgtgcac cacattttgg acattgtttt tctggcatgt caaatccaga
     6721 accatacgta ccatcttcaa aaaactcgga atattggcac tctggacaat aataatgagg
     6781 ggctaacgga ttaacttcag tgattcctgt catcgtcgca acaaagctag agccaacaga
     6841 gccacgtgaa cctactagat agccatcttc attactttta tgcactagtt tttgggcgat
     6901 cagataaata accgagaagc cattaccatt aatagaattc aactcttttt ttaatcgttt
     6961 ttgaatgatc tcaggtaacg gatctccgta catttgtttt gcttttgtgt aactcaattc
     7021 tgatatttca tcttctgaac ctggaatctt cggtgtataa agttcatctt tgactggaat
     7081 cacttcttcg cagatatctg cgattttatt cgtattttct actacgatct ctttcgctgt
     7141 ttcttcccct aaaaagtgaa atgcagttag catctcatcg gttgttcgga aatggacatc
     7201 cggcaaacta tgacgattca acggattcgc tccgcccata gaattgatca aaatttttcg
     7261 gtaaatggca tcttcttcgt tcagataatg tacattacct gttgcaacaa cgattttatc
     7321 caaacttttt ccgatttcta ccaaattttg gataatttct tccaaatcat gttcattttt
     7381 taccaattct tgctcgatca aaggcgcata gaccgctttt ggcataactt caatataatc
     7441 gtagaatttt gctcggtttc ttgcctcttc tacccctttt tgcatcatgg cttcgaatat
     7501 ttctccctta tcacaagctg agccgatcaa tagattttca cgcatctttt tcaattggga
     7561 gcgtggtatt cgtgggacgc gttcgaagta ttcgacattc gacattgaaa tcagtttgaa
     7621 caaatctttc agtcctgcct gattttttgc taaaatcgtt acatggaaag gtcgagccct
     7681 tttgtaagaa tctccttctc cgatatgctc atttagctga tcatgataaa gcatgttatg
     7741 attgtccatt gcctctttca caaagatcca tgctaagtga ccagttgctt cagcatcata
     7801 gattgctcgg tgatgctgtt ccaagctgac accaaatttt ttagataaca cacctaatcc
     7861 gaaacgtttg aattgaggat acagatatct agctaattcc aacgtatcaa tgactggatt
     7921 ggccgcttca ggaataccat accttgcgta gctagtattc aagaacccca tatcaaaagc
     7981 cgcgttgtgg gctaccaaaa ttgtatcttt tgaaaattca aggaacatcc gcaatacttc
     8041 ttcttccgac tttgatcctc gaaccattcc atccgtgata ccagtcagat ctaccgttgt
     8101 tcgtgacaaa ggatgtcctg gatcgataaa ttcatcaaag ctttcgatca catttccttt
     8161 atacattttg actgcggcta gctcgatgat cgtgtcatat actgcagaca atcctgtcgt
     8221 ttccacgtca aatacgacat atgtggcttc actcaatgct tcatgtgcat cattataagc
     8281 aattgggaca ccatcatcta cgacattcgc ttccacgccg tataagattt tcacacctgc
     8341 tttttttcca gcactatgtg cttccggaaa ggcttgcgca ccaccgtggt ctgtaatggc
     8401 gatagctcgg tgtccccatt tccctgcttg tgccacaaga tcagagatgc tgtttgttgc
     8461 atccatcgta ctcatattgc tatgaacatg aagctctact cgtttttccc cttcaggagc
     8521 ataatctttg cgaggtgtat gtttgacttc tatgatatct tgcgcattca tgaccaaatc
     8581 acggacaaac gtatcttctt gaatacttcc tcgtaccttt aaccagctac cgacactgat
     8641 cgcatcaaat acttgttcat ctttttcgcc gttcgagaat tttttgacga taaatgatga
     8701 agtataatct gtgattttca aagtcaagat cttgcgtttt gaacgtagtt ctctgacttc
     8761 tttgtcgaat acgtacccct caagtgtgac tcttcgttct tcttcaacga tactgatcat
     8821 tggtgtcgtt ggttcatcgg ctggaatatt tcgtcctagc tggatgtgga tgggtccttc
     8881 aagagctggc gattgctctt ttctttcctt tttcttttgt tcgtggacaa ctagactttc
     8941 agctgcttgc ttcataaagg cttctgcctg ttcttgtttg cgttcttcaa aaagtttcaa
     9001 tactcgttcc gcttgctgct catccacttc tggttcgata cgaaattttg ggaatccgta
     9061 actgacgaac aactcttcta ctaatggcaa gtattgttgc ttcaaataag aaatagctcc
     9121 tgtactgtcg attggcaaga tgactttacg atcttttatc acaggtacct gcgttttcaa
     9181 tacttgctgt gctagtggtg tatcgcattg ctgattttcc aaagcttggg cccagtaatc
     9241 ttgcaagagc tgttcatcga atgtctggtc atctgctaag atattcagtt tgacttgtgc
     9301 aatatcttta aaagcgatag tcagatgctg agtcaatgac cgatatagca taataggcaa
     9361 aattttggaa aaatgcagcg taaattccca taaacgcgat ttacgatgga ccactacact
     9421 atccatttca ccagcagtaa gcagtggatg atttttttct gcttcctcta gttggatttg
     9481 ttccaacagt ttttcaaata aatctcgttt ttctgacaaa gatatacgcc ctttctgatg
     9541 agaaacaatg caattgatcg catcttatcc tcttcttttt cagtaccttt tagtatactc
     9601 gttttttctg agttttacat taaaaaattg gaactgcgat tcaaatcgca gttccaattt
     9661 taaaagcgaa tcatcagatt gtcaaaaaca gctgattcag ctatttttat tttctgtgtt
     9721 ttaacgctta ttattcgcct tggttcaaga ggattggtaa agtattcacc aattcttctt
     9781 tacgtacttc aaccatttcg ccagttttct tgattttcac ttctacgatt ccatccactg
     9841 cttttttacc gacagtgatt ctgattggac agccaatcaa atcagaatcc gcgaatttca
     9901 ctcctgcgcg ttcatttctg tcatcaacca gtacttcata gccagctttt gtcatcgctt
     9961 cttctagttc attcgtcagg tttgtttggt attcgtcttt tagattcatt tggacgatat
    10021 gcaaatcaaa tggcgcaatt ccttttggcc agttgattcc ttgttcatct gaatgttgtt
    10081 ctacgattgc tgataataaa cgacttacac cgataccata acagcccata atcacaaatt
    10141 tttctcgtcc attttcgtct agtacagttg ctcccataga ttcactgtaa cgagtgccga
    10201 ttttgaagat atgtccgatt tcgattcctc gagtaaaggc aagaacacca ttgttgtctg
    10261 gtgaaggatc tccttcttgt acaaaacgaa gatcttcata agaaagtaca gtgaaatcgc
    10321 gttctggatt cacattttta tagtggaatc ctgtttcgtt cgctccagta atggcattcg
    10381 ctaaatcttg gacataacgg tctgcatata cttttacgtc atctgaaaca ccgactggtc
    10441 cgacagaacc aaactcagca cctagatatt tttgtgcttc ttcttctgtt gcttcttcta
    10501 aaaagtcagc agataaaaag tttttcagtt ttacgtcatt gacttcatgg tctccgcgta
    10561 ccaaaacaag gacaggttgt tcatccgcaa tgaacaatac agacttgatg attttttgag
    10621 gttcaacaga aaagaaatct gctacttcgt caattgattt tacgttaggt gtagctactt
    10681 tctccaattc aagctgtgtt tcatgcgatt tttttgatac atagtagctt gtagccatct
    10741 ccaagtttgc agcataatca ctttcagtcg aataacagat cgtatcctcc ccgatttctg
    10801 agatcgccat gaattctttt gagtctttcc cgcccattgc gccaccgtct ccgataatcg
    10861 agcgaaattc taagccacaa cgcttgaata cttcggtgta ggctttttcg taatctttat
    10921 atgtctcgtc caaactttct tccgttgcat ggaaagaata cgcatctttc atgataaact
    10981 ctcttccgcg aagcaaaccg aagcgaggtc gtttttcgtc acgatattta ggttggattt
    11041 gataaagatt taaaggtaat ttcttatatg aattgatttc attacgcatc aaatcagtaa
    11101 aagtttcttc gtgagttggt ccaaggatca tttttcgatc attgcggtct ttgaaacgat
    11161 acaagtttgg tccatatgtt tcgtaacgcc cggattcttc ccaaagttct gctggcaaga
    11221 tggcaggcat cagcatttct accgctccga ttttttcaaa ttcttcccgc ataatgcgtt
    11281 tcagtttttc caatacacga tttgctaatg gcagatatga ataaataccc gctgatactt
    11341 ggcggatata tccagctctt agcaagattt gatggcttaa tacttctgca tcatttggaa
    11401 cttcgcgtaa tgttggaatc aacatttttg attgtctcat tctatatact cctttatttc
    11461 ctcaaaatag ttatcgtttg ttattatacc ctatttgtca actttttcta gaaaaagaat
    11521 cgttgaatat cgttccatgt aactagcacc atcaacaaca ttaaaaatcc aaagccagct
    11581 aatgtcaata ttccttcttt ttcttgactt aatggtttcc cgcgaatccc ttcaaaaata
    11641 ttcaagacta atttcccgcc atctaaggca ggaatcggaa gcagattgac gattccgaga
    11701 ttcattgaaa gaagcgccat caaactaata acagttgtta caccttgatt tgctgcttct
    11761 gaagacaatt ggtacatcat gacaggtccg cctaatttat ctaaactgaa acctgtaaat
    11821 agtgatccta aggctttgaa aatttccaat gaaccgctga aagcttgacg cgtccctcca
    11881 atgatcttat ccataaaacc tgtattcatt ggggctttta taccaagttg gccaactttt
    11941 tcgccatttg actctacaga tttcggtgtc acgtcgacag attgcacctg accttctcgt
    12001 tcgatcttaa agtctaatgt tttatccgga tttttcgtaa tgactgttgt cagatcattc
    12061 catgaatgga tttcttttcc gtccacactg actacctcat cattttcttt taagcctgct
    12121 tctgccgcag ctccattagg catgatctct cctacgcgat tagtgttcgt cacttgaaca
    12181 ccaccttgca taaatgccag aatgatgaat aacaggattg ccaaaataaa gttattcatg
    12241 ggtccagcaa agttggtcag catacgctgc cacaatttag ccgattggaa ctgtacgtct
    12301 tttggcgcaa ttctgatttc tgttccgtcg ttttcaataa tcgtcgcatc gtgatcaaca
    12361 gggtaggtta ctacttctgt ttcgtctcca ttcacataac cagtgatagt cagctcatct
    12421 tctaaatcat aacggctcaa ttccatcggg atagcatttg tcaattggat tttcttactt
    12481 aaatttatct tctctacgat gccgtcagaa tttagtaaaa gagaaagagg cattcctggt
    12541 gccatttctg tttcatcatc cccattgcct gccattcgaa cataaccgcc aataggtaat
    12601 aggcgaagcg tatatgttgt cccgtctttt gcttgatgcc cataaatttt cggacccata
    12661 ccgatagcaa attcgcgaac gaggattcct gatcgtttcg caaagaagaa atgaccaaac
    12721 tcatgaacaa tcactaatat accaaaaacg atgataaatg tcagaatcgt tttcatagct
    12781 tttttctcct ttacttgttt tttgtgtttt ttataaaaca acgataaaac actataattt
    12841 taccatagta taccaaagac accaatagta tcaatataat gaaaaataaa aacctgcgtc
    12901 ttttatgaaa ttcacaaaga aacgcaggta tacttactaa ataatgccaa ataaatgcat
    12961 gataggaaat acaaacagca aactgtcgaa acggtctaag attccaccat ggcctggtaa
    13021 gatatttccc gagtctttca catcataatg acgtttgatt gcagattcga ccaaatcacc
    13081 aaattgtccg actgctgaaa aaataatcgt catcagaagc atgacaaaca taccatgatt
    13141 aaatagttct tttgctgggt atagcaataa ataaagaaat gcgactacaa cagcactacc
    13201 aataccaccg agcgcacctt caatcgtttt gttgggcgaa atatcaggac ttaacttatg
    13261 ctgaccataa cgtcgaccaa ccatatatgc tccgatatca gttgcccaaa caataaatag
    13321 accaaatatc aaaacagcca agctttctgt tcgtgcattg acaaaattct ggaaacctat
    13381 tcccacatac aagctgacaa gcacaggaaa acctgcttca tcaatcgtat acgtattttt
    13441 agaaataact gatgttccta aaagaatcat aactataaga taaaataaca taaatgtact
    13501 tacattctct ggaagaaaga aaaaccatct ttcttttggc aaaacaagta acactgcacc
    13561 aacggcggat aaaactcctt caaaacttaa gagtgtcaat cctttcatcc gaaacagctc
    13621 gtaaactcct attactgcta agattgctgc tgtaagctca accgctatgc ctccgatcca
    13681 tataatcgga ataaacaaga ctagcgccac ggctgctgtg accacacgtt gtttcatgac
    13741 tgatcccctt tctcatcttc tgtttttttt acaccgccga atcgacggtc tcgattttga
    13801 taagaggcga ttgcttcttc aagatgcgca ccatcaaaat caggccaaag cgcttttgta
    13861 aaatacagct cactatatgc gatctgccat aacagaaaat tactaattcg ctcttctcca
    13921 cttgtacgga tcatcagctc aggatcttgt aactctttag gcaagaaacc tgtcattaaa
    13981 tgcttagcaa tcaattcatc atcgatttct tctgcgtgta tttctccttt tgctacttct
    14041 tcggcaattt cttggacagc agtcacgatc tctgctctgc ttccataatt caaagcaaaa
    14101 ttcaatacca ttccagtatt gttttttgtt tgctcaattg cacgtcttac agcatcttgc
    14161 gtatgttctg gcaatacgtt ttcataaccc atgacatgaa ctttgacatt ttctttaatc
    14221 aattctggta cgaacgtatc aaagaagtcg acaggtagtt gcatgagaaa acttacttca
    14281 tcttttggtc gcttccagtt ttcagtcgaa aaggcataaa gcgtcaacac tttcactcca
    14341 agccttgatg ctttttttgt gactttcttt actgtttcca tgccttcttt atggccagca
    14401 actcgtggca aacgacggtt ttgcgcccaa cgaccattgc cgtccatgat gatggcaatg
    14461 tgctgaggaa ttggtccatc ggtattaaat tgaaattcgc ttttttcttg aatatatttg
    14521 tttttttgcg gaaaaaaacg taacattctt tttcctccta tacttaaaag attcccacta
    14581 tcttaagtat tatagcaata tctaactgtt tttcctatga aatcattgtt tttttattta
    14641 aaaactgaat aattttttct ttttttaatt tttaaataaa agaaatataa ataaaaacag
    14701 aggaagcgga atgatccgcc cctctgtttt tatgatttta ttaaacttcc aataattctt
    14761 tttctttatc agcagcgatc ttatctactt ctttgatgct gttatctgtc aatgtttgta
    14821 cgtctttttc taatccgcgc aaatcatctt cggtaatatc accatttttt tgttgttttt
    14881 tatattcatc gatcgcatca cgacggatgt tacgaatcgc gatttttgca ttttctgctt
    14941 cttttttaac atctttagct aattcttttc tgcgttcttc tgtcagttgc gggataacta
    15001 agcgaatgac atttccatca ttggttggac tgattccgat atcacttgcc ataatagctt
    15061 tttcaacatc ttgaagaatg ctcttgtcaa aaggtgtgat cattaaaaca cgtgcttctg
    15121 gaatttggat tgatgccatt tggttcaatg gtgttggcgc accgtagtag ttcacagtaa
    15181 tacggtccaa aaggctagcg ttcgcacggc ctgcgcggat ttgcccaagt tcacgttgaa
    15241 gattttgtgc tgcttttttc attttttctt ttgcttctgt cataattgca tctgccattt
    15301 ttatttcccc cttacagttg ttccgatatt ttcgcctaag attgcacggc gaatatttcc
    15361 gtgttcattt aaattgaaga caagcagtgg aatatcatta tccatgctta gtgaacttgc
    15421 agttgaatcc atgacttgta atcctttggc aataacttcc agatgagtca gttcttcaaa
    15481 ttttactgca tttgcatcta ctttcggatc agcagaataa acaccgtcta cattgttttt
    15541 agccatcagg ataacatctg cgccgatttc tgccgcgcgt aatgctgctg ttgtgtctgt
    15601 cgagaagtac gggttgccgg taccgcctgc aaagataacg atccgtcctt tttctaaatg
    15661 acgttctgct ttacggcgaa tatatggctc tgcgatttga cgcatttcaa tcgaagtttg
    15721 cacgcgtgtc ggtacaccca cgttttccaa cgtatcctgt aaagctaagg cattcataac
    15781 tgtagctaac atacccatgt aatcagcttg agcacgttcc atgcccattt gtgctccgat
    15841 ttgtccgcgc cagatatttc cgccgcccac aacgattgcc atttcaacgc ccagctcgtg
    15901 aacttctttg atttcttgga tgatttcttt gattactggt ggtttgattc caaatcctgc
    15961 gtccccagct aaagcttctc cactcaattt taagactaca cgctgatatt tcggtgtgac
    16021 catgttcatt cctccaatat tttctattgc cattttacca tacttagatg atttcgacac
    16081 tctaagactg gtttttcttg ttttgcttaa aaaaagggag cgcacaaacc gtgcgttccc
    16141 gtctgttatt caacagaatt attttttcac ttggctcata acttcttcta caaagttatc
    16201 ttcgcgtttt tcgatacctt cgccaacttc gaaacgtacg aatgttttaa cagttgcgcc
    16261 ttttgatgca acgtattttt caacagtcat atcaggatct ttaacgaatg gttggtccac
    16321 caaagcgatt tctgctttga atttcttcaa gcgtccttct accatttttt caacgatatt
    16381 cgctggtttg ccttcgttca atgcttgttc tgtaagaaca gttttttcat gttctaattc
    16441 agcttctgga atttgtgatt cgtttacata acgaggattg atagctgcta cgtgcatagc
    16501 tacgtctctt gcaactgttt cgtcagttgt tccatctaga acagtcaata cggcaatacg
    16561 tccgcccata tgcaagtatc caccaaatgc agcattgtcg tctttttcta caacttcaaa
    16621 gcgacggaag ctgatttttt ctccgataac ttgagttgct tcgatcaagt cagattcaat
    16681 tgtaccttta tctgttttga ttttcattgc agcttccatg tctgctggtt tgttttcagc
    16741 aacaagttct gcaatttctt ttactaaatc ttggaacatt tcgtttttag aaacaaagtc
    16801 tgtttctgag tttacttcaa cgattgctgc agtgttacct ttcacagcaa ctgaagccaa
    16861 tccttcagct gcaatgcggt catttttctt cgcagccttt gccattcctt tttcacgtaa
    16921 aagatcaact gctttttcca tgtcgccttc tacttcaact aatgcttttt tcgcatccat
    16981 cattcctacg ccagtcattt cgcgtagttc ttttaccatt ttagctgtaa cgtctgccat
    17041 gtttaactcc tcctgtgtgt ttttcttttt aaaaaaagct gcttcaaagg agagtgaggc
    17101 ttgtcgccca gcctttgaaa cagctccatc attcaaaatt attctgctga agaattgtcg
    17161 ccttcaacaa catctacgat ttcttcgatt gatgttgctg tgttttcttc tgtgaaatct
    17221 tcttcaacta cttgatcttc accttggttt ccttcgatga aagcatcagc catttttgaa
    17281 gtaatcaatt taacggcacg aattgcatcg tcgtttgaag ggattactac gtcgatttca
    17341 tctggatcgc agtttgtatc aaccatagct acgattggga tatttaattt gtgtgcttct
    17401 tgaacagcaa tacgttcttt acgtgggtca acgatgtaca ttacatctgg gattcttggc
    17461 atatcagcga taccgcctaa gaatttttca agacgttcac gttctttgtt caaaccagca
    17521 acttcttttt taggtagaac ttcaaaagtt ccatcttctt ccattgcatt gatttgtttc
    17581 aaacggctga tacgtttttg gatagtatcc cagtttgtca atgttccgcc taaccaacga
    17641 tggttaacga agtattgtcc tgcacgagtt gcttcttctt tgattgcttc ttgtgcttgt
    17701 ttttttgtac ctacgaataa tgctacgccg ccttcttcag caacgctctt catgtaatca
    17761 taagctgcat ctactaattt aactgttttt tgcaagtcaa tgatgtagat tccgtttctt
    17821 tctgtgaaga tatatttctt catttttgga ttccagcgac gagtttggtg accaaagtgt
    17881 acgccggctt ctagtaattg tttcatagaa attactgcca tgtttgtttc ctccgatttg
    17941 gttttatttt tcctcttctt atcttctacc ttgccggcaa actttttcaa gcacctaccg
    18001 acaatccaat aagaatgtgg atttgctgat gcataaagca ccctcagcta ttatacagac
    18061 aaaagatccg tatcgcaaga gcaaatatac ttttctgctc aacattcaat agtttacctg
    18121 aaagataaaa agaattcaag aaaaacagta gatttctctt tgtttcttta ttatcctttt
    18181 tccataaaat aattttaggt ataaaagacg aatattattg ggcaatcctt cttttttttg
    18241 ttatgataca tgtgaaatct ttcgtaaagg agaaagaaaa tgcgcaaagc tcaaagacat
    18301 ttgctgatta aacaagtcat tgaagaattc ccgatccgta cgcaagaaga actattaaac
    18361 aaacttgggc attatggcgt taccgccacg caggcaacga tttctcgaga tatccgtgat
    18421 ctaaaaatcg tgaaggcacc tgatgaaaat ggcgtttccc gcttcgtatt gtttcgcgaa
    18481 aaaggaactc ctgagactag gactgaggaa gaggatcggc tggttcaaat gattgaagac
    18541 attgtattga aagtcgaacg agtccacttt ttgacgatcg tcaatacctt gccagacaat
    18601 gctcatttat ttgcatctgt tttagatgag atcaaacctc cctctattgt cagtacaatt
    18661 gctggattcg atacgatcat ggtcatctcg gaaaatgagg aggacgcaaa acgagtagaa
    18721 gaatttcttc accatccaac tgaagtatca cttttttaat cagagcacgt attcctaata
    18781 tggaatgcgt gtttttttat tttcaatatt ttccttattg aataaacctt tacactcttt
    18841 acaaaaatac atcatttttt attcaaattt ttcaacacct tgattgaatc acaataatca
    18901 tcatttatat tggatgttaa caagagcagc ttcttgctct ttgtgtattt caaaaaagaa
    18961 atgaaaggaa atcatatgta taaattatta acttctggac cattgacgac ttctgaaaca
    19021 gtgaaaaatg ctatgctgat cgatcattgt acttgggatc aagaatacaa agaaattaca
    19081 caatggataa gaaaaaaatt attggatctt gctcaagtat cggaaggaat atacacaacg
    19141 gtcttaatgc aaggtagcag ctccttcggg gtagaatcgg tattaagttc tgtgatcagg
    19201 ccagaagata ctgtactgat ttgttcaaac ggcgcatata gacaacgaat gatcaacatg
    19261 tgcgaatgtc tgaaactgaa ctataccgtt tatgaggtat cggaacatca aatcctccaa
    19321 gctcatgtga ttacacagct gattgaagag aatccgtcta tctccgcact agcaatggtc
    19381 catagcgaga ctacttccgg tattttgaat aatttggaag agattgctgc tgtcacacaa
    19441 gaaagagatc ttttgtttat agtggacgcg atgtcaagct ttggtgggat accgatttgt
    19501 gtagccgaac tagggattga ttttttgatt tccagctcaa acaaatgtat tcaaggtgtt
    19561 ccaggctttt cttttgtact tgctaataaa gcggaactgg aaaaacgaaa aaatgttagc
    19621 cgaagtttgt cacttgatct atatgaccag taccgcgtga tggaaaacga gaatggcaaa
    19681 tggcgtttca cttcccctac ccatacggtt ttggcttttc aacaagcgct gaaggaacta
    19741 gaggcagaag gaggaatcga aactcgatat tcacgttatc tcgccaataa tcatgtgcta
    19801 cgacaaaaaa tgacagagat ggggttccag cctttcattc aagaatatca ggggccattc
    19861 atcacctctt ttctttaccc taaggactgg cgatttgatt ttaatcattt ttatcagtat
    19921 ttaaagcaaa atggatttgt gatctatccc gggaaaatca gcgatcatga atgttttcgt
    19981 atcggaaata ttggcgagat ctatccggaa gatattttgg aactgacagc aattatcaaa
    20041 gactataagg agaacgttaa tgattaaaac tgtaattttt gattgggcag gaacaactgt
    20101 ggactttggc tgtatggctc ctgtccacgc ttttagaaat gcttttctag aaaaaggaat
    20161 ccaactgact gacaaagaaa tccgctaacc gatgggaaaa ttaaaatggg atcatatcca
    20221 acagcttctt tccctccctt ctgtcaaaaa acaatggata gctatttatg gacaactacc
    20281 tcaggaaaaa gaggtggagg aattgtatca acaatttgaa cattatctgt ttaaagattt
    20341 ggtcaagcat tctaccttga aacccgacac attggaaacg atcgaacggt tgagaaacgc
    20401 tgggatcaat attggttcca cgaatggatt taatgctcct atgatgacaa tcgtagcaga
    20461 aaccgcaaaa aaagaaaggt attcaccaga cttcatggca acttttgaag acgtcgaagg
    20521 gtatggtcga ccgtttcctt atatgatcca taaaaacatg cagtacttca aaaacaagtc
    20581 ggttgatgaa gtaatcaaag tcggagatac ggtctcagat atccaggaag ggaaaaatgc
    20641 cggagtgttg acagtaggtg taattgaagg tagttcgcta atggggattt cttatgatga
    20701 gtaccaaaaa ttagagatgg ggaaaaagat cgtttaaaac agtctgttgc tcttagattc
    20761 caacaagccg gcgctgatat ttgtgtaaac aatttaaaag agttaacaga atacattttg
    20821 tacgctgaca tgaatccaga atgactttta tacaaaataa gaggttgtga aaaagctgtc
    20881 ctgtatcaag taataaaaac agccaagcaa aaatagctcc tcatattttt cgtttggtta
    20941 ggcttattac cgcagatgca agcttttgaa caccgtttat tcgaaaaaaa aaagggagct
    21001 gtgacacgac ttttgtcaca gtccccttat ttgcaaacaa acagtgttta agagacaacc
    21061 tctccactaa acggtgttca ttcagctgac tctcggtatt tgctcaaaaa acgataaaat
    21121 ttgaaaagct attttctctt ttgtttctct aatactcgga tcagaacgct gatttcacat
    21181 tctctttttc ttacatctta tctggtgcat gaagtcctag caaacgaagg tcttctttca
    21241 ataatacagt cactgcataa actagagcta agcgtgcttc tttttgttca tcatcagcta
    21301 aaatcttcgt atgagcatag tatttgttga atgcttgtgc taatttgatt gcatgtttcg
    21361 caatcactga cggttcgtat ttttccccag cagacaagac cgtttcaggg tatttttgaa
    21421 ctaatttaac cacttcccag ctggtatcgt cattcaatgc atagtctgct gtttctgaag
    21481 ggacaaatcc tgctttttcc aacaggctga ctgcacgagc atgtgtatat tgcacataag
    21541 gtccagtttc tccttcaaat cgaacaactt cttccaggtt aaagtcaaat gtattcagtc
    21601 gatcgttttt caaatcgtgg aaaatgactg ccccaacccc aacttgttta gctacagcat
    21661 ctttgttttc caaatcaggg tttttctcgc tgatttgttc tttagcagat tggattgctt
    21721 catttaatac ttcttctaat aagacgatct ttcctttacg agttgataat tttttaccac
    21781 cttgcgtgat caaaccaaat ggaatatggt gcatgtcgtc agaccagtca aagcccattt
    21841 ccttcaagac agctttcaac tgtttaaaat gatagctttg ttcattccct actacatata
    21901 gagattgttt gaagtcgtaa gtacgtttac ggtacaatgc agcagctaag tcacgtgtaa
    21961 tgtatagtgt cgcaccgtct gacttcttaa tcaacgctgg attcaggtca taagcagata
    22021 ggtcaacgat ctctgcacct ttatcctcgt tcagcaaatg tttttcttct aaaagtttga
    22081 cgatttcatc catcttgtca ttgtagaaag cttcaccgtt caacgaatcg aaacgtactt
    22141 ccagcagatc atagatttta ttgaattctt tcatcgattc atcacggaac cattgccata
    22201 attgaatagc ctctttatcg ccttcttcca gacgtttgaa ccaagcacga gcttcttcat
    22261 ttaattctgg ttctgtttca gctacttcat ggaattggac gtataaacga agcaattcat
    22321 tgattggttc tgctttaaca gcttcttctg taccccattt tttgtaagcg acgatcagtt
    22381 ttccaaactg tgttccccag tcacctaaat ggttgatgcg gattggctga taaccgattt
    22441 tttccataat gaaaccgatc gaattaccga taactgtcga acgcaaatgt cccattgaga
    22501 ttggtttggc aatattagga gaagacatgt cgattggtac tgttccttga ttcccgatgt
    22561 tgctatcccc ataatgttct ttttctttca ctactgtttg caaaactttt ttgctgataa
    22621 gttctttatt catgaaaaag ttcaagtaag gtccgacaac ttcgattttt tcaaagttgg
    22681 cagaatcgat tttttctgct aaatctgcag cgatttgctg tggcgctttt cggtaaactt
    22741 ttgctaatga aaaggctgga aatgcaacat ctccgtgttc agctgatttt ggattttcta
    22801 gtaattgctc gacttgttcc agtgttaaat catctttgac agcgtcatag acagcttttg
    22861 cgacaagatc tttattattc atctttattc ctcctaaagt gttcccttga ttgttaaaca
    22921 aaaaaaatct ctagcgacgg catacttagt atgccatcac tagagacgag atttcccgcg
    22981 gtaccactcc aattgtccta aaaaaggacc agctccatct gatatcggta gacgaccgtc
    23041 tgtttaaaac agaattctcc aagtgcgctt cgttgtatct tcttcattcg gcttccacca
    23101 cttccgaatt cgctagccaa gaatgataca agtactctct tgttcaacaa atcttagtct
    23161 tattaaactt tcttgaatta tatcagaaaa aaaaacgaaa ggctagtcgt ttcataaaaa
    23221 aacaatccag atggcctaaa ggagaagaaa taccacctgg atagctataa atcatttcgt
    23281 aaatacgaaa gacttaacaa attaatcagc tacgataatc gttccttctt cagaagctaa
    23341 aagattctcg atattttcta aagaagtgat gattgcctta gcgtttggtt ttgcttcaac
    23401 aaatgcaata gctgcttcta ctttcggaag catgcttcct ggagcgaatt gcttttcatc
    23461 aatgtattgt ttcatttctg aaacagtaac agtttctaat ttcttttgat ctggtttttg
    23521 gtaattgaca tacacattgt ctactcctgt caatacgatc agcaaatccg catcgatgat
    23581 ttcggctaat ttttctgaag caaaatcttt atcgattacg gcttctcgtc cttctaatcc
    23641 agtagctgtt tctacaacag gaatcccacc gccaccaaca gagactgtga taactccttg
    23701 atcgaccagc gtttcgatga cacgtgcttc tttaatcgag atgggtttag gggaagcgac
    23761 tacttttctc catccacgtc cagcatcttc tttgaatgtc acagtggagt cagcattcat
    23821 ttgttctttg gcttcttctt ccgtgtagaa tggaccgact ggtttacttg gatttttgaa
    23881 tgaaggatca ttttcatcca caataacttg agtgactaaa gaaaccacat ctttatcgat
    23941 ccctttttcc ttcagtactt cgcccatggc gttttgtaac cagtaaccga tagatccttc
    24001 tgtcattgca acacatgtat ctaaaggcat tgccggtgtt ttctcagaat cagcagcttg
    24061 ctgctgaatc aataggttac cgacttgcgg accatttccg tgggagatga tcaattcatc
    24121 tccttgttcg ataaatttca ctaaatactt tgctgtttcc attaacgctt cttgttgggc
    24181 ttttgcactt gcatccgtag acaagatggc attgccccct aaagcgacaa ctacttttcg
    24241 tttggccatt tcattcgtcc tttcttcagt tctaccgaat tttctagata acaaaacgag
    24301 ccagcgtttt gtgattttcc ctcaatgctg actcgttttt tcgtgagatg aatgtggtta
    24361 tgcttaaacg cgagggataa acaagttacc taatgttgct gccatgatcg ctttgattga
    24421 gtgcatacga ttttctgctt ggtcaaattg acgagcatat ttgctgcgga agacttcatc
    24481 tgttacttcc atttcagtga tgccaaagcg ttctttcatt tgttcaccgt aaacagtgtt
    24541 tgtatcatgg aaagctggca agcagtgcaa gaagatcaaa cgatctgtgt tgtgtgtttt
    24601 ttctaccatt tccatattga tttggtaagg tttcaacaat ttgatacgtt cttcgaattt
    24661 atcttcttca cccattgata cccatacatc agaataaagg acgtctgctc cgtctacacc
    24721 tttatcaaca tcgtcggtaa tcatcaattg tgcaccggat ttttcagcaa agccttctgc
    24781 cattttgacg atttcttctt caggttgtaa ttcttttggt gcaacgatac gcatattcgc
    24841 tcctaaaatt gcacctgtga ctaataaaga gttagccata ttgtttcgac catctccgca
    24901 gtaagcaaca gtgatacctt ctactgttcc aaagttttct tggatagtta aaaagtcagc
    24961 gatcatttgt gttggatgcc attcatcagt caagccattc caaactggaa caccagagaa
    25021 ttctgctagt tcctctacca ttttttgact gaatccacgg aattcgattc cgtcaaacat
    25081 acgtcctagt actttagctg tatcttctgt ggattctttt ttacctaatt ggatatcatt
    25141 tgcacctaga tattcaggat gtgcacctag atcgatcgct gcagtagtaa atgcagaacg
    25201 agtacgtgta gatgtttttt caaataaaag cgcaatattt tttccttcta gatagtgatg
    25261 tgggatacca cgttttttca agtctttcaa gtgttctgaa aaatcgatca aatattgtaa
    25321 ttcttctttt gtaaagtctt tttctgctaa taagcttctt ccttggaata ctgattcttt
    25381 catattaaac attctccttt agattgtttt tatttaagat taaagaggaa atcccgacgg
    25441 cagctgacag taagactgcc gtcaggaaac aaattacttc aagtcttcac ggacaagtgg
    25501 ttggctcatg cagcgtggac caccacgacc tcgtgacaat tcacttgaat tgatttctaa
    25561 cactttgatg ccatagctac gaagcaattc gttcgataca taatttcggt tataagtgac
    25621 tacaacacct ggagcgattg ccaatgtgtt tgatccatca ttccattgtt ctcgaggtgc
    25681 aacgatctca tctccattac cagttgggat cagtacaaga tcatctaatc caagagcagc
    25741 tttcatcgtt tcgtgtaagt tatctgaatg agtaatcttg atatcatcac catctggttc
    25801 gattgtaaag acatccatct taccgtcttt actttgaatt gctggatgga tagtgaattt
    25861 atcgtgatct accattgtaa atacggtatc caaatgcatc attgcacggt tgttcggaat
    25921 tttgattgcc aacacttttt caaatcctga attttttgcg aataggtggc gtgctaattt
    25981 ttctaaagct ttcgcattag ttcgttgaga aatcccaaca gctactactt tatcgcttaa
    26041 gatcaattcg tctccgcctt cgatatgatc tggattttca cgatccaacc atacttcgat
    26101 tcctttattt gcaaatcttg gatgatgttt caaaatatat tctgtaaaca tcgattcacg
    26161 acgacgtgct tcaaaagtca tcttattgac tgtcatccca tttcccattg atgcggaagg
    26221 gtcgcgtgta aagtacaagt ttggcattgg gtccatgtaa aatggatagt catcgtctgc
    26281 tgacagatca tatagactgc tagaacgtac ttcgatatct tttgtacgaa ccccagccat
    26341 gattttatct accatttctt gcgtttccat tgatagaagg aactcatgaa gaccctctct
    26401 tacagcattc gatgcaatat gagattcatc caacatttta ttcaagaatt gttctttgac
    26461 attgcctgcg tcaatcgctt ctgccgctaa tttttccaag taaagagtct cgacgccttc
    26521 attttgcaat gtcttcgcaa agttgtcatg ttcttcttga gcaatcggaa gatatggaat
    26581 atcatcgaac aacagacgat ccataatatc tggtgtcaaa ttttccactt cttgtccagg
    26641 ccgtttcagt aaaactgtct ttaatttccc tatttcagag aaaacgtgaa taggtttatc
    26701 catgttgtgt tgcctccttc tttttgatta catgtatagg atatcctcct tttgtaatca
    26761 ctttcataat tttgtctcat tcaaaatgag acattcctca cattaatatt cgataattaa
    26821 ataattaaac gtttttctat ttttaagcgt aatttattca ttttttattc tgtatacact
    26881 ttcaaaaaaa tatttattca ttgaaaaaat ttttttgaat aaattaaaaa aataaattat
    26941 attatcgttg ttagcgttta ctatatgtat tattgttgtt ttttatacac aaatcattcg
    27001 cttcaaaaca aattattcaa taccattgta tattttttac ataataacaa attatatttg
    27061 taaagtatta aaacttgttt ctaatgttgg tatgttaaaa ctttacaaat tctttaaaaa
    27121 aagtgacaat aaatatagtg aacaataagg agaggacttt ttaatgcgtg ttaataaaat
    27181 cgattttcac ttttcaaaac tcagatatca acctgatttt gaacatttct cggatgaaga
    27241 gttccaacag atcaaggaac atactgttct tcgttcttat aaaaaaggac agatcctttt
    27301 cgacgatggt gatcccagac aacggttgta tatcttgacc aaaggactcg ttcgtttaga
    27361 acgttatgat gaaagtgcaa cttattacta ctatgactat gtgaatacaa ataacctttt
    27421 tcctatgtca ggaatgtttg gagaagagac ctacacttat acagctcaag cgatgactga
    27481 tattgaaaca ttctaccttc ctgtttccta ctatgaaaaa ttagcacgaa aaaatcccga
    27541 acagttgatc tatatgatac aaaaaatttc taaagtagtt gaaatacatg aattgcgtat
    27601 ccaaatcgga ttgacctcta gcgcctttga ccgggtaaaa caaaatttat tcattttgaa
    27661 agaagaattg ggcgtaccaa caaaagatgg tcatatcacc attccttatc cgatcacctt
    27721 aaaagaatta gcagtgaata gcggcacgac acgtgaaact gctggacaag taatcaaaca
    27781 actacgtgat tccgggctgt tagattatga caaaaagcgt tttactttct gtaagacagc
    27841 tactactcca gctatgagag aataacgcga acaaaaataa gcagtgaccc tgataaatat
    27901 cagggtcact gcttattttc ctccctaaaa cttctgaaag atccggcagt tttagatcac
    27961 tggacaagac tcaaagattt tctatgtgtg tttcagttat gtaatattca ctgtttgcaa
    28021 aaaatactgt tagattaact agatgaagcg tcttgtcctc atccgatcta gattattcga
    28081 tattcctcga caataaacga ttactcagtg agggcaatca gaggaacgga taatgataaa
    28141 taagctgtaa aaaatagcaa aataacaata atgattaaaa gtatgtaaaa aatagggctt
    28201 tgacaaaaac gtgtcacagc cctatttcga ttaaacggtg tgtacctgtc aactcttcgg
    28261 tcacaagtca taatgttcat aaacatgagg agctgttttt tgaaattgtt ccttgtgaat
    28321 cagagttaaa cgacaggctt acgaactctt gattaaacgg cgttcaaaag cttgcatacg
    28381 cggtaataag aacagccagg tcaaaaacat gagaagccgt ttttcctggg ctgttcttat
    28441 tacttgatgc agggcagctt tttcacaacc tctttattca gataaaacca agcttggatc
    28501 agcattcaac tgatagctag caaaatttct tttttgcatt tccacatgtg ctgctgctcc
    28561 aatcattgca gcattatctc cacaaagtcg aagaggggga atcactagtt ctacctcagg
    28621 gagtttagct gccaaagcat cctgcaatcc ttcacgcaac ccttgattgg ccgctacacc
    28681 tccagctata atcagttgct tgactggata attttgacaa gctcgaagtg ttttagtaat
    28741 caatacatcg atcacacttg cttgaaagct agctgctaaa tcatttttgt ctagatcttc
    28801 tccacgctgt tgtgcattat gcaccaaatt gataaatgca ctttttaatc cgctaaaact
    28861 gaaatcataa ttatcttcat ggatcatcgc tcgcggaaaa tggtaattat cttttccctg
    28921 atgagctagc tgatcgattt cttttccgct tgggtaagaa agacctaata ctcttccaac
    28981 tttgtcataa gcttctcctg ctgcgtcatc tcttgtctcc ccaatgattt catatgatcc
    29041 atcttcttgc atatagacta attctgtatg tcctccgcta acaagaagtg ccatcaatgg
    29101 aaactggaat ggtttaacca gacgggctgc atagatatgc cctgccatat ggtttacagg
    29161 aataagcggc aattggtgtg cccaagcaaa agccttagct gcagaaatac caatcagcaa
    29221 cgagccgaca agtcctggtc cataagtgac agcgactgcc gataaatctt ctgccgacac
    29281 accagcttct accagtgcat cttccaagca taaggtgatt tgttctacgt gatggcggct
    29341 agctacttca ggtactacgc caccaaaacg tttatgactg tttatttgag aagcaacgat
    29401 gttagataag atctctgttc catttctaac gaccgctaca ctcgtttcat cacaacttga
    29461 ttcaatcgcc agaatcaatt cttcattcat ttcatcgtct ccgtttttaa ctttctgctc
    29521 ataatgatcg catcttccgt cggattgcga taatatgatt tccgtttacc taatatacga
    29581 aacttttctg attcataaag ttttcttgct gcttcattag atagacgtac ttctaaaaaa
    29641 acatgcagcg aatcttttat ttgttccgta atcagtaatt gtaacaaatg ccgtgcatgc
    29701 ccttttcctt gttctgaaac tgcaacagca atatttgtga tctcgacttc atctattact
    29761 ttcgagtatc caataaagcc acagatctgg ttatcttcag ctaaaagcag ataatcagag
    29821 tgaggctgtt ggatgtctgc caaaaactgc attttcgtcc aaggtgaacc atgtggataa
    29881 gcattttcgc taatcatcca tacgcattct gccaagtacg cttcatcaaa atcttttttt
    29941 ctgcaaatca actaatctca ctcattttct aaaagtttta tcatatccaa cgcatcttct
    30001 tttgtttcag tgtaatatct ttttttgatc gttgttgctt gaaaccccaa tttccgataa
    30061 agtctttgtg catcttgatt actcatacgc acttctaatg acatcgtctc acagcgattc
    30121 attatagcaa agttctcgat ttcgtcaata agcagcgaac cgattcgttt acgctgatat
    30181 gccggtcgaa cggcaatatt cgtgatatgg caatctaaac cgaacgctct tgaaccgata
    30241 aaaccaatca ttcttccatt atcaaagata cctagatata gatgaggaag cggtgacttc
    30301 aattctgata taaaggcact ttttgtccat ggcaattcgc cattatagac ttctcgttcg
    30361 acatccagca gctctttgat atcttctgta gtcaattctc ttagtacgta acgacgatcg
    30421 atttgttcga ctgttttttc tgtataaatc attttatctt gaaaaaagct tctggcatac
    30481 gctctaaatt ttttcaacat aactttcgtc tccaggtgtg tgcgtctcca accatttttc
    30541 ttctgcttct actcgtttta aatagcgagg aagaaaagct tgtttctctg caactggttc
    30601 aactaaagca cctaattgag ccacagttac accacttgga atatcccatg ctggaactgt
    30661 attaatcatc gcactaggca atatttcctt tatttcagag aagaatttgt gacaatcact
    30721 cccgacgaaa taaatagctt cattcagctt ttgtagttgt gtgaacaaat cagaagcaga
    30781 aatatgtaca tcttcaagta cagtttctaa tctattttct ttccagcggt atgccccagc
    30841 gtatacattt tttcttcgag catcaaacat gggcacaata atattatcca caccgatgca
    30901 attagccgcg atggttttca gactagatac tcctactagc tctttatcta atgtataagc
    30961 aatcgttttt gctgtcgtta cacctatacg aagccctgta taagaaccgg gaccatcaga
    31021 aaccgcgatt cggtcaatgt cttttggact tatttgaaga tctgcaaaca attggtcgat
    31081 tgcaggcatc agtgttacac tgtggttgcg tttgatattt gtttgtattt gtccaagaat
    31141 ttgttcgtct tctaccacac cgatcgccaa agtttggttt gcagtatcta ttcctaatgt
    31201 aatcatatat ttgatccttt ctgctatgac attctcgcct tccattgtag catacttttt
    31261 tattctgagg atgaaaatac caaaggcaaa actagtacaa taatacatga ttatctgctg
    31321 gcgggcaaat tttgcccctt cctgaaacac aaaaaagctg cggtatcact ccattttccc
    31381 acagcttttc catcttttat ttcgttgatt ctcgaataat caactctgtt tccacaataa
    31441 tctttcttga aaccggtgct ttggaattac ttaattgaag aatcgtctcc actgctagct
    31501 ctcccatcca ttcggtataa acttttacag tagaaagcga gggcgttaca tatttcgcta
    31561 cactgacatc attgaagccc atcacagaaa tatcttctgg taccactaaa cctttttctt
    31621 gaatcgcttt cagtgcgcca atcgctaatg catcattagc tgcaaaaagc gcatcaggaa
    31681 catgcggatt cgtttttaaa tattgcttca ctgcttgata tcctgactcg acagaaaaat
    31741 ctgcttcgat aattggacct tcgtcgtagc ctttttctgc caaaacttgt tgaaatgcca
    31801 taattctggg atcttttagc cgctgatggt ttttcttcgt atattctgtt ccagcaagca
    31861 tagcgatatg ttgcgcttta tgggagacaa agtgttcaat gactttttga acacttgact
    31921 taaagtcgac aactagagag tcgattcctt gagaagtgcc gtcagaatct accaaaagca
    31981 aggcattttg ggatcctttc atttctaata actgagcttc gtcgaatttt cctagtgcga
    32041 tcgttccatc tgccggaaga tcactaatgg aatcccacgt ttctttcaat aaagtaacgt
    32101 ttgcttcttc tgcctttttt tcgattccta ggcgaataga taaataataa agatcttcaa
    32161 gctcttccgt atcgtcgtac cactggatca ggcgaagcgt ttgcttagta tttgctgcat
    32221 ttttacgatg tttcgtataa tttaagcgtt ctgctgcttc aaaaattttt tgctttgtgg
    32281 ctaagccaac ggaaagatca ggatcatagt tgagaactct tgaaacagta gcaggagaaa
    32341 ctcctgccaa ctgcgcaatg tctttaattg ttgccatttg tctctcctcc ttttttacgt
    32401 ttataaaatc gcagtaaatc gttcaaacgc tgcctgtcct ttttcatctc gcttgaatac
    32461 tccagcgtct tccagtacac gtgcaaaaac ctgacctaca gatttttgta cgacatcggt
    32521 gaccgtatct ttcgtcaaat caggatgttc tttttttaat tgttctgccc acggacgatg
    32581 atattcagcc atctggtttt cttctcctaa taagaaatgc tctacttcta ctagttctgg
    32641 tttcaaacga ggtggtaaaa cagcaagccc cattacttcg atcaacccaa tgttctcctt
    32701 tttgatatgt tggacatctt tatgtggatg aaaaatccca tcaggatgtt cttctgaaac
    32761 attgttgtct cgaaggacaa ggtccaactc aaagtaattg tcccttcttc gtgcaattgg
    32821 cgtaatcgta tggtgtggtg taccatctgc tgaaaaagct ctgatagata ctgtttcatc
    32881 cgaatatgct ttccattttt ccaatactga gttagctgct tcaataagca agtttttctc
    32941 tgttgattgc aaacggatca cagacatcgg ccatttcacg actcctgcga tgacttgcgg
    33001 ataatcttct agtttgataa gtttttctat cggtgctttt gccataggaa attcatgacg
    33061 tcctgcctga taatgatcat gagaaagaat cgatcctcca acaattggta agtcagcatt
    33121 cgaaccaaca aagtaatgag gcaagacttc agtaatccga agcagtctag caaatgtttc
    33181 ctttgtgatt ttcatcgggc ggtgttgttc tgataaaatg atcgaatgtt cattgtaata
    33241 agcataaggg gaatattgga atccccagct ttcaccgtct agattcattc gaataatccg
    33301 gtgattggtg cgggctggat agttcaagcg acctctatat ccttcgtttt ccatgcaaag
    33361 catgcaggta ggatagtcta cttttaccgc ctcgcgttct gctgcgattt gttttggatc
    33421 tttttctggc ttagataaat tgattgtgat ttccagttca ccatactccg actctgccgg
    33481 aaatttgatg ttttttgcga tggctcttgt tttgatgtag tcatttttct tacttaaatt
    33541 aaagaaatac tcagttgctt cctctgggct tttcgaatag tgctgtgcaa agaatgcatt
    33601 gacgactgaa ggtggcggtg tgagaaaatc cattaattgc gcttcaaaaa tctcttgttc
    33661 tgctggcaat tctgaaagaa caccattttc tcttgcctta gcgacaagct gatccaataa
    33721 gtctacagat tcttccttaa ctggtcttac ttcaatgctt tctagagcat cttctcctac
    33781 catccctaaa agacgattct gtaaatataa gcggtccatt tccatccatc cgccagcttc
    33841 gatcgcaagt gtggcaaaat cacaaatcgt ttgactgatt gacatatctc attcccctat
    33901 tcttcataac catttggatg gctgacatgc caatcccatg ctgttttgat aatcgctttg
    33961 atatctgtgt attcaggttt ccagcccaga atctctctcg ctttttcact tgaagcgact
    34021 aatcggctag gatctccagc tcttcttggt gctatttctg ctggaatttc ttttcctgtc
    34081 acttctctag ctgcttctag catttccttg actgagtatc ctttgctgct gcctaaattg
    34141 aagaagttgc tttcatttcc ttctttcaag tattccaaag ctaaaatatg tgcagcaatc
    34201 aaatcttcta cttgaacata atctctgata catgttccat ctggtgtatc ataatcgtct
    34261 ccataaacag ccaaggcttt tctttgacca agagctactt gtaaaatgat tgggacaaga
    34321 tgcgtttctg gtgtatgatc ttctccgata gatgcatctg cttttgctcc ggctacattg
    34381 aagtagcgca aagcgacata gcgcatgcca tatgcttggt cacaccactt catcattttt
    34441 tccatcatca atttactttc accatacgga tttttaggat tagctggtgt atcttctgtg
    34501 attggagact ctttcggctc tccataagtt gctgcagtag aagagaatac gattttattc
    34561 acgttgaact cgtgcatgac ttcaagtaag atttgcatac cgtatacgtt gttgttgaaa
    34621 tacatcaatg gtttttcgac agattctcct actaaagagc ttgcagcaaa atggattact
    34681 ccttcaatcg gttccttttc aaatacggaa cgtagaaatt ctttatcccg gatgtctcct
    34741 tcataaaaat gagcatctgg atgtactgct tgtttgtgac ctgtgagcaa attatctacc
    34801 acagctactt gatacccctt ttgaactagc tggtctacag cgtgcgaacc gatataaccg
    34861 gctccgccta gtactaaaat tgtcataaaa aacactcctt tgattagtaa aattgtgttt
    34921 gttgattcta tataatttaa aaaacgaagt ttacttttat ggtgaaaaca aacaaagtaa
    34981 aatttcgtaa attcatatgg taaatttata ataaaacatt tagtaaacat tttcaagggt
    35041 tttttgcaaa ggtttacaaa caaacgtaaa actagccttt ttttctcttt tgttccataa
    35101 tagatataac aaataataaa tgaggtggat tcaatgaaaa aatttgtatc tggaatatta
    35161 gtaggaagtc tggcaacagc cgctgccgtt gctggtttgg ttgcttctgt gaaaaaaaca
    35221 gtgatcgatc caattgacga aaaagaagca atgatcgaag aaaaccgtaa aaaagcaatg
    35281 cgtaaacgcg tttctcgtta ataattattt aaaaatacgc atgaagactt tctaaaaaac
    35341 agataagtca tcatgcgtat ttttatttgt cagtcaatat aagttgtgct attttatctg
    35401 cctgtctcag attccatgga tctgtataag gtctagctac tgctgcagtt agccaatcca
    35461 caccttcaac aggtattcca tagcaataaa agtcagactg gatttcccct gaagcatcaa
    35521 tcacgcgatt cgtacctcgc tcaacatcta tagcttctga atgataactt cctgtattat
    35581 ctgaaaatga aaaagggcga acaagtttgt tttccttcaa attttttatg acaggattac
    35641 ttgaacgaga aaagcttgtt tgtggcaatc gagcttcaat caaatagcga ctgctgattt
    35701 ctttatcttg tagagaaata acatagcggt tgtgcttttg ctgaatatca aatggcggtt
    35761 cgatcaaatg aaaaataccc gcatctatca gtgctgctaa ttctttcgtc cgaatgattg
    35821 gcggaccgat cgttaaaaag ctatttagat gagtaaacca tccccatagt atttctttgt
    35881 attccttagc agaaaaaacg tgccattcaa tagcctgccg gattggatca cgccagtctt
    35941 ttaatgcatc aaatgttgaa gcaaatgctc ctgtgcaatt gcctttttcc gcttctttta
    36001 tctgcccttc aataaatatt cggctagctt ctgaaaaggg ctcattctga taggcaagag
    36061 gagtttctaa atacgaccaa tcccatctat aagggattag tgctggatgc tttccgagac
    36121 actcctctga agagagggag agaaaatcat gctcaaaatt tttctttgga atcggcaagt
    36181 gatattcttc gatgattttc ttgtaataaa acaactcaac gtcttttttc agatagtcaa
    36241 aaaatgtttc gccagtcaaa aatcccgact gatgccattg ctccaggttt tcttttgtta
    36301 gtaaccgtgg ccatgccatt gctccgcctt gcttttgatt tcttcctcga gggtaataag
    36361 ggagccccct tcttgatcca ctgtatacaa tcggttcctt gcctgatgga tgatagacca
    36421 gttttccctt ttcgttctcg aagcgccctc ctcttgatac tgtaaacaat ccgacataat
    36481 caaaaaaact taagcctaga cctcttaaaa agacattttc tttaggcggt atcttcgaaa
    36541 gatctacatc tgcaggatta gaaggaagct gatacagtaa aacatttttc tttgcgtagt
    36601 ctacccacac tctttcttct tctgtctcat cattttccca gtgaccgctt gctaaaacaa
    36661 gctgatcgat agaatagctt tgctgatctg tctgtaaaag ataaccatct tttcttttgc
    36721 ttactttttt tactaaagaa taaacaaact gaatagaagc tggaaattct tcttgcaact
    36781 ttgagaaaaa ccagcgttga tagagtccgt ataaacatcg agtagattgc tgatcttttt
    36841 ccagacgatt gatttcttct ataattagtt gcttattttt ggttaccgtc tgttcgatat
    36901 aatctgtagc aggtccttta ctccattgaa acaagttggg tccctgtgtt accaatcctc
    36961 cactggacaa tgtttcatct gtaaaaagcg tcacttgttg agaaacagaa ttcattaata
    37021 actccggtgg ctgattcaac cgccaaactc gacctccagg accattggga tcgaaaagaa
    37081 aaagttcaag agaatgtctg tcctgattat tatggagaat cctttctgct acacttaatc
    37141 ctctaggtcc ggcaccaatg atccctattt tcatttgcat gcctccattt cgataaattt
    37201 tttcaataaa acagcatggt tctgatgttc attttttgca ccataaacaa aagtaatgac
    37261 tggatgttct ttcataagtt gactgagttt aaaaatagct tgcttctttt cttcttcgaa
    37321 aatcaattct tgctggtatt tctttgcaaa tgaagcaaat cgttctggta catggtcaaa
    37381 agttttgcgt gcttcattac taggtgcaat ttctttcaac cacagatcta actgcgcttt
    37441 ttcttttgaa attcctcgtg gccagaatct atccacgagt attctatagc catcctcttt
    37501 ttcagcatca aggtaaacac gttttaattt gatcatagtt gtttccttct ttctaccttt
    37561 tcgcttagct tatatatgta gataatagca caaaataaaa aaaatgaacg gcacaactat
    37621 ccattgcgcc gttcatgtga tcttggtcaa aatctaatga ttgattcggt ttttaaagct
    37681 gtcatacaat catctgtttt atactttttt acttttgatt tttccagacc atccgtcata
    37741 tccaccctta agtaaataaa tctcttgata acctgcttta cgtaatttat ttgctgtacg
    37801 gatgctcaaa cttttctttt gatcgtaaat atagacaggc tggtcttttc gaatagatcc
    37861 taatgaatct ttcaaaacag tgtaagggat gtttcttgca cctaaaatat gcccagcatc
    37921 aaacacatct ttttcgcgaa catcgattac ttgtgctttt ctcattcctt ctcgaaattc
    37981 ttcttctgtc aaagtcgttg ctgaacgttt ggccattact cgtagataga cttcccaaag
    38041 gatgattgca agcacaatca atagcaaaat gatattaatt acccataaaa ccatgtaatg
    38101 cctccgtttt tttaagcaaa tttcaaggct aatgaggcag caccaatgac accagcttca
    38161 ttaccaagct ctgctaattt gatttttgtt gattctctta cttgcgggaa agtaaattct
    38221 ttaaaatatt tctctacacg gctacgtaaa aattctcctg ctgccgatac tcctccacct
    38281 aacacgatac ttgacggatt taatgtattc cccaagtttc cgcaagctaa acctaagtag
    38341 aagcatacgc gatcaacaac catcaatgca aacggatcgt cttcttgagc catttcaaag
    38401 atatctttac ttgttacttc ttctccgttg tctagcattg ctttcagttt tgaatcccct
    38461 gcgtattctt ctgccaagaa acgacctagg cgtaccacac ctgtagcgct agatacagtt
    38521 tctaaacatc cgcgtttacc gcaagtacat tcgaaccctt caggatccac agtgatatgt
    38581 ccgatttctc ctccagctcc gctcacgccg tgaatcaaat ttccgccagc aacgatacct
    38641 ccgccaacac ctgttcctag agtaacgaat acaacgtctg gatcgttttc tccagcacct
    38701 ttccatcgtt cacctaaagc agcaacattc gcgtcattat cgatagcgaa tttgattcct
    38761 gttcctgcct cgatcagttt tttcacaaat tgaacttctg tccagtttaa gttatacgca
    38821 ccaataaccg ttccagcttc gctgtccacg cttcctgggg tacccatgcc gattccgata
    38881 aagtcttcgg ctttcatatt atataaattc aaacgatgat tgattgattc aatgatttca
    38941 ggaacgatat gcttaccatc atccaaaata ttggtatcga tgctccattt ttgctgaatc
    39001 tctccttctg gtgttaaaat tgcaaatttt gctgttgttc cacctaaatc aatcccaata
    39061 atcttcttgt ccattacaaa tttcctttct ttcggctttc ttcaattcgg tgctctcttt
    39121 ttaatatgcg ccacgctgtc atgtatgtat catgatcaat caaacggcta tcatacagat
    39181 tacgcaattc gatagtcatt aattcaatgt catagatgcg tgcacccaca tagataaaga
    39241 tgccaaattt tttgaacagc tgctgtacat catataagct ctccatcttt aagcacttcc
    39301 ttcatattat acaagtaaac catatttttt taaacccagt aaaatacata ttacaaaaag
    39361 aaatacaaaa actagtgtag aaagaatcct ttggtgtatc gaatagcttg tctgttgttt
    39421 cggtagaccc aaaacattcc ctaacactaa tccgccaatt agcccaccga catgtcccca
    39481 aacatctaca gaggtatcca gaagaccaaa aacaaatgtc aacacaataa ataaaagaaa
    39541 atgtctgact agctgctgga tcgctgggtt atgtttaaaa tgaaacccta agataaacaa
    39601 cgcaccgaac aaaccgaata tcgaagtact tgcaccacca gacagaacat tcgcttcgtt
    39661 aaaagcaaag cttgctgtat ttcccattat cccgctgaac atataaatca agaaaaaacg
    39721 ccaatggcca tagattgcct cgatttgctg ccccataaaa tacagtatca gtgagttcat
    39781 tacgaaatgc atcagtccaa aatggatgaa gattggtgtc actaaacgcc accattcatt
    39841 gaagtgaaca agataaggac catacattcc ggcataataa gggatctcaa gtcgcggaaa
    39901 taattccatc atgaggaaga ccgctgtctg tatccctaaa aaagcatagg tccataacgg
    39961 tcgtcttaac catgcacgca attttatttg ctgttgataa ttcatgaaaa cctcccattt
    40021 cattttagtc aataaacaat tgttggatct tctgatcaaa gctctccggt tgccattgtt
    40081 cattcaattg ttcacgaaaa acaaggctac atgttttttt atgaaaatta tttaaatacc
    40141 ggtcgtaata accaccgcca aaaccgattc gataaccggc tctattgtag ataatacctg
    40201 gtacaatgag gagatcgatc atctccggca aatagagctt ctctgattgt ggctcaagaa
    40261 caccaaaact cgaacgtaca agaacggact gttcatccat ttcataaaac gccatctgac
    40321 gtttcggcaa agttttaggt acaactattt tcttttgttc tttttctgct cgttggataa
    40381 ccggctgtgt atccagttca aattcattcg ataaagtcgt ccctatcact tttgctgact
    40441 tccagtactc gctggcgaat agctgtttat agattcgctg ttctttttcc tttttcttgc
    40501 cacttttggc cagatttttc agcttttcga ttcctttccg gcgtaatctt actttcaatt
    40561 ggtccaaaaa ctcacccttc cttctctcat aaaatggtat aggaaaaaaa gaaaaatagc
    40621 aatcgaactt tcaaataaat gcataaatag aataaaaaga agacctagaa atgattggcc
    40681 ttcctttttt aatgaatttc aactgttcag cgcgtgtttt tgtctgataa aaagtgcata
    40741 cagaaaatat ggcgcaccaa aaagggcaat caaaattcct gtaggtactt ccccacttgg
    40801 tagaatcact ctagcaacca tatctgcact aagcagaaaa atggaaccga acaaaccgct
    40861 cagaacaaag gtccagttat tttctttacg tacgactagc ttcgcagcat gaggagctag
    40921 tagtcctaca aaagataaac tacctgtcac cgctacacta ccgcttgcca aagcaacagc
    40981 taacaacaaa aggatttttt gacttttagc cacgttaagg cctaatcctt gcgcgcgttc
    41041 ttgaccaaat gatagcaata caatcctctg tgcataaagt cctcctagcg gaattaagat
    41101 aaccgcccat ggaagcaatg cccaaacata aggccagctc gcaccccaga ttgatcccgc
    41161 taaccatgca ttcacaaatc cataattttc cttagataat tggatcgtgc atagcaatgt
    41221 taatgcagaa aggccggcat taacggcaat accggacaat aagattcgat tcatacccaa
    41281 aaagccattt cgatcatagg ccgcaagata gacacagcaa gcagctaaaa caccacctag
    41341 aaaggctaca actagcaata gaaacggcag cgaatagtgc gaaaagaaac ctaaataaag
    41401 catcactaaa aatcctgctc cggcattaat gcccaatata ctagaatctg ccaattcatt
    41461 tcttgttact ccttgcaaga tataaccaga aacgccaaga caagctcctg ctaataaact
    41521 gatcagtaat cgaggaactc gaaattctct aacaatcagc gccaaagaag atgattcttt
    41581 ccctatgaac gtggcaaaaa gctgatccag gtaaataaaa ggcgtaccaa tcattaaact
    41641 acctatagac aggatgacaa gtacaaaaag caagaaatag aacgtccaat atattttttt
    41701 caccgttgtt ccctccttac ttgtatcagt aaaaacggaa cgccaatcaa tgcaatgact
    41761 aatccaaaag gtgtttcaaa agggggattg atcatcctcg ctgtaaaatc cgccaacata
    41821 accaatccac cgccaactaa aaaagagaca ggtagaacat aacgatagtc cgttccaacc
    41881 attccgcgaa caactggcgg aaccaacagc ccaataaatg aaacaggtcc gactaacgaa
    41941 acggcaatgg ctgctaacac tgcaactaga cagaaaacaa tcaaccgcgt tcgtttagga
    42001 tgacttccaa gagctaatgc atgtgtttca ctcaaatgaa tcaaagatat tgcttttcct
    42061 aatgaaaaag aaaccaaaac agcaagtata tataaaggaa acaatactgc taattgtttc
    42121 catgtgatat tggcagctcc gcctacaaac caaaaagcaa gatcctgctg cagattaaag
    42181 aattgggtaa gtgcttggct gatagcagta aaaaaagaac taatagctac gccagctaaa
    42241 atcagctgta aaggattcat gcccattttc gaaaactgca aaaaaccaaa tacgagcaaa
    42301 gttacagcaa aagaacctgc caatgacatt agaaacacag aaaaatcaga agctttaggc
    42361 caaaaagcaa aactaagggc cattgccaac gaagcacccg cgttgattcc tagtaagcct
    42421 gaatctgcta aaggatttct tgtcactcct tgcatcaatg caccgctcaa tgcaaaacaa
    42481 ctccctacaa gaaatgctcc cgccacacga ggcaaacgaa tatttcgtat gatttggtga
    42541 ctttgttttg atctatcaaa atcaaacaac gcctgccaaa aatctgcttt ttccacagtc
    42601 gctgcgccat ttgaaagagc aacaaaaaaa ataatcaaaa gaacaaaaca gaccaaaagc
    42661 aggagtctat ttttcttcat agtcctcata attgatcctc ctgctctttt ggcaacaaat
    42721 cataggttag aaaaactggt ttatttgttc ttggaagcgt gacaatcgtt gcatcaatct
    42781 caaatatttt tttcatacac tcttttgtga tcacttcttc aggtgtacct tctgtgatca
    42841 acttaccgtt tttcattgct aataaataat ctgaaaaacg tgaagcatga ttaatgtcat
    42901 gaatcgacat caagatcgtt gtttgtttca tttgattgat ttcagtcaat aactgtagga
    42961 tctctaattg gtgtgccgga tctaaaaatg ttgtcggttc atccaagatc aagatatctg
    43021 tttcctgagc aagcgccata gcgatccaga cacgctgggt ttgtccacca gacagcgttg
    43081 cgatatcccg catacgaaat ccagctagac ctgtagcatc caacgcccac tcaattgctt
    43141 catgatcttg cgtgtccatg ccactgaaca gtttttgata agggtatcgt ccgtaagata
    43201 ctacttcttc tactgtcata cctgtagggt gttcactagt ttgtgctaat aatgcaattt
    43261 tttttgcaag ttcttttgaa ctgtatgtag agatatcaga gttattgaca atgatctttc
    43321 ctgatttcac aggtagtata cgggtaaaac ttttcaataa agtagatttt ccacttccat
    43381 ttggcccaat caaactagtg attttccctt caggaatcgt aacagacatg ttttcaatga
    43441 tttttttgtt ttcgtagccg gctgcaatgt cagctgctct taatctcgtc atttcaccca
    43501 tcctttcgct gaaaatcatt ctcaattatg acgctgtttc aacatttcgt caagcgctac
    43561 tttcatatct atagccaaat gaagcggttg acagcgttcg aaatatcagg aataataacc
    43621 aatgagaaag attctcaatt atgttaggag gaaagaaatg aaattaaaaa caaaagtatt
    43681 cacattatct agcatattgc tgctggctgg agtactgagc gcttgctccc cctcttcaga
    43741 taaagaaaca gctacaactg ccaattcgac gacttcatcc aatagtactc atacagtcac
    43801 agatacactt ggacataaag tagagattcc aaacgcgccc aaacggatca tcggcagtta
    43861 cttagaagac tatctgattg cactagggga aaaacctatc gcccagtgga ctgttggcag
    43921 tggttccatt caagattatc tgcaagatga tttaaaggat gtcccaacga tttcttatga
    43981 ccttccttat gagaaagtgt taagctttga gcctgatttg ctgttgattt cttcttccgc
    44041 tactgtcgaa ggcgggaaat acgaacaata tagcaaaatc gcgccaactt atgttgtaaa
    44101 aaacggaaca gatgtcacat gggaagaaca actaaaagat gtcggcaaag ctttggcaaa
    44161 agaaaaagag gcagaaaaaa tcatttccga ttatcaaaaa tccatcaaga aaactcgaga
    44221 agaactagca gataaaatcg agaacaagac agctgcagtg ttgtgggtga ccaacaactc
    44281 agcctttatg gtcagcaaaa atcggtcaag tggaagaatc gtatacgacg atctggaatt
    44341 tggtgttcct gatctagtgg aagaggtctc caaaaaagcc acttctgact ggtctgctgt
    44401 ttcctctgaa aagctagctg aattagatgc tgactacatc atccttgtga acagtgacaa
    44461 agatgctgcc atgttcaatg aaccaagctg gaagaatcta aaagcagtga cagacaatca
    44521 tgtactgcaa ttcggacctg aatctagttg gctatataac ggacctattg ccagtcagga
    44581 aatggtcaat gatatcaaag aaaaactaaa ttgattttaa ctaaaaaaag catcttcacg
    44641 attagtcgtg agatgctttt tttcttatta acaaactaga cgcatagatt ttattcttct
    44701 tttgaagcaa ccctattttt tactctttcc catttttgaa aacgatgggc atatagattt
    44761 tcttgatccg ttatcccctc atactcctct ataagggcga agtctgaaaa atcaatattc
    44821 ccaatatacg tatcgccttc aaacgtgcta tcgatcaatg ttcgccagat ccgaccagtg
    44881 taaggaagaa gttcttgaaa aatccgacta ccacccgaaa catagatatc ttctgagatc
    44941 gtttgactat acgacaaaag ttcatcgatc gaatgcatta cttccgcatt ttctttcgtg
    45001 cgaaaatttg gttgcgttgt caacacgatg atatggcgat aaggaagtga aagatccccc
    45061 attccttcat aggtctttct tcccatcact aaaattcgat ccattgtatg ttcgcgaaag
    45121 aaacgcatat catttggcaa tcgccatggt aacaaaccat ttttgccgat cagaccattt
    45181 ttatcttgtg cccacatgga aataaacata ttatccgctc cttatgattt tagatgtttt
    45241 gagataaaaa aagtctcaat tctttgacca gcaaggaatt gagaacttta aaaacattat
    45301 tttgtttcac ggtgcaaagt aactttgcgt tcgcgtgggc aatatttttg tttttccaaa
    45361 cgatcaggat tgttacgttt gtttttgctt gttagatagt tacgttcttt acaagaagta
    45421 cactctaaag tgatgtttac gcgcatgttt ttccctccca tttttacaag aatcctctaa
    45481 gatgactctc agacttgatt atcttaccat gattttttct agattgctag tgtttttcac
    45541 gattttgtta agtaaaacta cttgacgata aatacaacgg ttttacttct caaacaaaat
    45601 ctttttcttt ttgtataaat acccttacac ttgtttatat agattatgtt ttttaataaa
    45661 gggggatact aatatgccat ggaacatgaa ggactttcct gcatcaatga aaaacttaga
    45721 taaattgaca agaaaaaaag caatcgacat cgcaaatgca ttattagatg aagggtaccc
    45781 tgataaccgt gcgatcccaa ttgccattga tcaagcaaaa aaatggtatg aagatgctag
    45841 tgaatcagaa aaacgaactt tcgaaaaaga aaaaaatcca agcaagacgg atgaacacga
    45901 tacgaatcct cgtgctggaa aactgcttga ttcagatgtg atcgtagaat atgaggaaga
    45961 acaatggatc gtgaaatcta aaggggcaaa aaaggcaagc aaccattttg atacaaaaaa
    46021 agaagcaatc gaaaaaggaa agcaagtagc acaaaacaaa gaatcaactt tgttcattta
    46081 taaaaaagat gggacaaaag aaaaagaaat cgattattga acatatgtaa aggggttgtg
    46141 acgaaaatcg tgtcacaacc cccttatgtt cgaaacaatg gtgttcctct gccaactccg
    46201 aaccataagt cataatatct ataaaacggg aagagctgtt ttttgaaatt gtttcttatc
    46261 actcagtgtt aaacggtagg agaaaacctc ttttttattg atatttgatt ttcatcaaac
    46321 agtcacatag tcgattgctt ctgcttgcgg aatcgtttca tctacaaagt agactttata
    46381 ccatgtcaag aaactgaaga ttgtccagat ttttctttgc tcttctttac gtccttcgtg
    46441 atggtcatct agcaacttca tgattttttc ttgatcaaaa aattcttttg caaaatctgc
    46501 ttcgaataat gctttgactt gttcgtagcc gtgttcttct ttcaaccaag ctttgattgg
    46561 cacagggaat cctaatttca cacgattcga ccattcttcc ggaagatgtt tgttcgcagc
    46621 ttgtctgaaa atatcttttg tgttgttttg attcaataaa aacttacttg gtatttgttg
    46681 agccaatttc atgacttcga tatccaataa aggtactcgg acttccaaag aacttgccat
    46741 agaaagttta tctgccttta acaagatatc ttttggcatc cattgatgaa gatcgacata
    46801 ttgcatctta ttgacttcat ctttgattcc ttctgttttc tcgtaatgaa cagtcatgat
    46861 ttcatccaca gatggtgctg tttgatattt tggtgttaac acttctgatg cttctgattc
    46921 ttcgaacact cgagcatgac cgataaaata ttcttttgca ggagcaagtg attcatataa
    46981 atggatccgt ccatggaagt ttttcatttt tccgatttta cgtcctaaat tatagcgtgt
    47041 tccttttggt aattttttca atccttgagc aatcacacgg atgaattttg aattcgtatg
    47101 gaatccatac gtttggtatc ccgcaaacag ttcatccgcc ccttctccag attggactac
    47161 ccgcacactt tgtgaagcaa gatttgctaa aaagtacaaa ggtacgcaag aaggatttga
    47221 atcaggttca tctaagtgat actggatcaa agggaatgct ttgaacgaca tgtctccgtc
    47281 gatcactgct gctgtattat ctaagtccaa tagttcggtt agttttctgg cttcaatcgc
    47341 ttcattatag gttttatcat caaacccgat tgagaaagaa tgatctggtt tcaatacaga
    47401 ggttacataa ctggaatcaa ccccgctgga taagaaagaa ccaacttcta catcactgac
    47461 cgtatgtgct tcaatagaag cttgaacggt ttcgtcgatt ttttcgatcc attcttgtcg
    47521 ggaatgcgtt tcttttgttt caaaatctgc atcccaatat tgctgaatgt ctatttttcc
    47581 atctttatac gtataataat ggccttcagg caaacgatag acatctttga agaatgtttc
    47641 gccgtttaat ggagaatatt ggaaagtcat ataaggtttc aacgcttctt tgttcaattc
    47701 tttgttaaaa tcaggatgag gcagaaaact tttgatttct gaaccaaaca taaatgttcc
    47761 gttcatttct gcataataat atggtttgat cccaaagtgg tctcttgcac cgaataactc
    47821 attcttttca ttatcccaaa tagcaaaagc aaacattccg cggatctttt gcaataattc
    47881 tgttccccat tcttcgtaac catgcaaaag gacttctgta tctgcatgtg tttgaaaaac
    47941 gtggccagct gcaatcaatt cttctctcaa aggctggtaa ttatagattt cgccattaaa
    48001 aataatgatc tttgtccgat cttcattgta aataggctga gtaccgccct ctaagtcaat
    48061 aatacttaat cttctgaatc ctaaagcaac atgtttatcg atatattctc ctgaactatt
    48121 aggtccacgg tgaacgattc gatccatcat tgtattaata attgtttttt tgttgtcctt
    48181 gtcgttaaca aaacctacaa taccgcacat ttaactttca catcctaata taaaattact
    48241 gtttatttca ttcatatgca tcttatcata gaataaatag cggacgaata ttttctctct
    48301 tacaatttcg tcacgtgaaa acaaaagatg aaagtttctg tttttacaga aaataaagtc
    48361 ccaatatcta atttaccatg ttttcttttt tgaggctacc ttattctctt cgtgttaaaa
    48421 aaatattagt ggatgctatt tccaaaaaaa ccagcaaaaa aagacacgac ctaaagatcg
    48481 tg
//
LOCUS       DAFENC010000020        45883 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.020, whole genome shotgun sequence.
ACCESSION   DAFENC010000020
VERSION     DAFENC010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 45883)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45883)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45883
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.020"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            9..731
                     /locus_tag="LP493_001425"
     CDS             9..731
                     /locus_tag="LP493_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBL2133584.1"
                     /translation="MLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEPKSIPTTLNVAL
                     IGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGMNKINAAYSYGG
                     VDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSLDLDGVYINKGE
                     QVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFKLPKAVGKLLGS
                     IQTNLPESVLLDCGMDFLKDIC"
     gene            789..2828
                     /locus_tag="LP493_001426"
     CDS             789..2828
                     /locus_tag="LP493_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HBL2133585.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKIITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFQTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLINPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(2937..4088)
                     /locus_tag="LP493_001427"
     CDS             complement(2937..4088)
                     /locus_tag="LP493_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBL2133586.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(4242..4772)
                     /locus_tag="LP493_001428"
     CDS             complement(4242..4772)
                     /locus_tag="LP493_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBL2133587.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(4871..5221)
                     /locus_tag="LP493_001429"
     CDS             complement(4871..5221)
                     /locus_tag="LP493_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HBL2133588.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(5378..6907)
                     /gene="ahpF"
                     /locus_tag="LP493_001430"
     CDS             complement(5378..6907)
                     /gene="ahpF"
                     /locus_tag="LP493_001430"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HBL2133589.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(6917..7480)
                     /gene="ahpC"
                     /locus_tag="LP493_001431"
     CDS             complement(6917..7480)
                     /gene="ahpC"
                     /locus_tag="LP493_001431"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HBL2133590.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(7624..8286)
                     /locus_tag="LP493_001432"
     CDS             complement(7624..8286)
                     /locus_tag="LP493_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2133591.1"
                     /translation="MKSSSQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            8470..10116
                     /locus_tag="LP493_001433"
     CDS             8470..10116
                     /locus_tag="LP493_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBL2133592.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAALLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPDMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDFQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            10107..11189
                     /gene="uxuA"
                     /locus_tag="LP493_001434"
     CDS             10107..11189
                     /gene="uxuA"
                     /locus_tag="LP493_001434"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBL2133593.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFELPGWEP
                     ERLAHIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLP
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNEYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(11297..12850)
                     /locus_tag="LP493_001435"
     CDS             complement(11297..12850)
                     /locus_tag="LP493_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL2133594.1"
                     /translation="MQTQEAIKTFLLKKKSNTKLDIFLFLSEHRFFITTQYLADHFHM
                     SESNFLLYIKELEQDFERLNLTELHIDKQKPFLKLNFEGIDPAYCYYRLFGRYCNESV
                     SYQILTSLFSCQTNSIISLSQQTNYSASYLYTKMKKINAFLALYGLSISFSNNGRKSF
                     SGKEVQIQYAALDIYWNIFSSTATEFYDEDPQVVAFMMNTFFKKEVLDRLNSGMIDKL
                     YFLLKICKENFPATSVKDVQKEFTEYEYIDFFIDPSVDILRPNLPICREQRILVNILA
                     RLSITKIESEETSLEQYKLLKKANVPHVLYSREMVESFCTVFDLFIPEKEKILYSLAF
                     ARNKLYNGFLNFNQPNTPLPTFMLYQEHSVLKEVQTAIEQFYMDFREQNQHLLPVILE
                     KENVQWMVEDLVHLYDRYKKQPRIVIGVNYTRDFYISKDLIVKIEQIFSNESIKIQND
                     FMENCNIVISDCPLKQLPSHIKKIYILKGIITPEDWKKVIMRISEYIFELKEEALMDQ
                     SKKENQVTS"
     gene            12998..14286
                     /locus_tag="LP493_001436"
                     /pseudo
     CDS             12998..14286
                     /locus_tag="LP493_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(14412..15491)
                     /locus_tag="LP493_001437"
     CDS             complement(14412..15491)
                     /locus_tag="LP493_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL2133595.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(15594..16034)
                     /locus_tag="LP493_001438"
     CDS             complement(15594..16034)
                     /locus_tag="LP493_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL2133596.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(16091..16501)
                     /locus_tag="LP493_001439"
     CDS             complement(16091..16501)
                     /locus_tag="LP493_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBL2133597.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(16681..17115)
                     /locus_tag="LP493_001440"
     CDS             complement(16681..17115)
                     /locus_tag="LP493_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL2133598.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(17215..18063)
                     /locus_tag="LP493_001441"
     CDS             complement(17215..18063)
                     /locus_tag="LP493_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL2133599.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            18452..20218
                     /locus_tag="LP493_001442"
     CDS             18452..20218
                     /locus_tag="LP493_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HBL2133600.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            20320..21579
                     /locus_tag="LP493_001443"
     CDS             20320..21579
                     /locus_tag="LP493_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBL2133601.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            21726..23027
                     /locus_tag="LP493_001444"
     CDS             21726..23027
                     /locus_tag="LP493_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2133602.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            23030..23881
                     /locus_tag="LP493_001445"
     CDS             23030..23881
                     /locus_tag="LP493_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2133603.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            23894..24709
                     /locus_tag="LP493_001446"
     CDS             23894..24709
                     /locus_tag="LP493_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HBL2133604.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            24860..26026
                     /locus_tag="LP493_001447"
     CDS             24860..26026
                     /locus_tag="LP493_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL2133605.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            26256..26903
                     /locus_tag="LP493_001448"
     CDS             26256..26903
                     /locus_tag="LP493_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBL2133606.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            26987..27931
                     /locus_tag="LP493_001449"
     CDS             26987..27931
                     /locus_tag="LP493_001449"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HBL2133607.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            28066..29517
                     /locus_tag="LP493_001450"
     CDS             28066..29517
                     /locus_tag="LP493_001450"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HBL2133608.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            29538..30374
                     /locus_tag="LP493_001451"
     CDS             29538..30374
                     /locus_tag="LP493_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBL2133609.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            30374..31033
                     /locus_tag="LP493_001452"
     CDS             30374..31033
                     /locus_tag="LP493_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBL2133610.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            31159..31848
                     /locus_tag="LP493_001453"
     CDS             31159..31848
                     /locus_tag="LP493_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133611.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            31854..32810
                     /locus_tag="LP493_001454"
     CDS             31854..32810
                     /locus_tag="LP493_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HBL2133612.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            32854..33366
                     /locus_tag="LP493_001455"
     CDS             32854..33366
                     /locus_tag="LP493_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2133613.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(33622..34170)
                     /locus_tag="LP493_001456"
     CDS             complement(33622..34170)
                     /locus_tag="LP493_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL2133614.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(34259..35440)
                     /locus_tag="LP493_001457"
     CDS             complement(34259..35440)
                     /locus_tag="LP493_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HBL2133615.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(35676..37184)
                     /locus_tag="LP493_001458"
     CDS             complement(35676..37184)
                     /locus_tag="LP493_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HBL2133616.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            37343..37534
                     /locus_tag="LP493_001459"
     CDS             37343..37534
                     /locus_tag="LP493_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133617.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            37737..38654
                     /locus_tag="LP493_001460"
     CDS             37737..38654
                     /locus_tag="LP493_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HBL2133618.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            38647..39720
                     /locus_tag="LP493_001461"
     CDS             38647..39720
                     /locus_tag="LP493_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133619.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            39868..40386
                     /locus_tag="LP493_001462"
     CDS             39868..40386
                     /locus_tag="LP493_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133620.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            40367..40759
                     /locus_tag="LP493_001463"
     CDS             40367..40759
                     /locus_tag="LP493_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HBL2133621.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVVFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            40835..41770
                     /locus_tag="LP493_001464"
     CDS             40835..41770
                     /locus_tag="LP493_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HBL2133622.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            41903..42682
                     /locus_tag="LP493_001465"
     CDS             41903..42682
                     /locus_tag="LP493_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBL2133623.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            42675..42992
                     /locus_tag="LP493_001466"
     CDS             42675..42992
                     /locus_tag="LP493_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBL2133624.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            43236..44846
                     /locus_tag="LP493_001467"
     CDS             43236..44846
                     /locus_tag="LP493_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBL2133625.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            45003..45851
                     /locus_tag="LP493_001468"
     CDS             45003..45851
                     /locus_tag="LP493_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBL2133626.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
BASE COUNT        15234 a         8277 c         8823 g        13549 t
ORIGIN      
        1 tatctatttt gttactgctt acattagtag ttggctattt ttcgattgag tttatccatg
       61 gattttcgtc tgcaaaacag agttcaactg tgaaaaaggt agagccgaaa agtatcccta
      121 ccacactaaa tgtggctttg attggttcag atgctcgttc gaaagacgaa aacggtcgct
      181 cggattcact tctggttgca caatacaacc agaaaacaca acaagcaaaa ctgatctcta
      241 tcatgagaga ttcatatgtc gatattccag gttacggaat gaataagata aatgcagctt
      301 actcttatgg gggagttgat ttattaaatc aaacattaaa ggaaaatttc aaatttgaag
      361 ctccctatta tgcaagtatc acatttcaag attttatcga ttgcgttaat gaactgtttc
      421 ctggtggagt caagatcgat gcagaaaaat ctctagattt agatggcgta tatataaaca
      481 aaggagagca agtgatggat ggtaatactt tactccagta tgctcgattt cgggaagaca
      541 aagaaggaga cttcgggagg atcagaaggc agcagcaagt gatcaaagct atctctcagc
      601 agctgaaaga cgtaacttca atattcaagc tacccaaagc ggttgggaaa ttacttggta
      661 gtatccaaac gaaccttcca gaaagtgtgc ttctggattg tggtatggat ttcctcaaag
      721 acatatgtta gaataaacag gtataaatag tgaaataaag gaatgacaag caagagaagg
      781 aggaaaaaat gaaaagaagt gacaagcacg gcaaaaatcg aacaggcgct tatattgccg
      841 gcgcagtgat cttaatagca gctgcgggtg gcggttattt ttactaccag cactatcaag
      901 aaacccaagc agtagaagct ggagaaaaga cagttgagca atttgtccaa gctttgaaca
      961 agggagatta taacaaagct gcagaaatga catcaaaaaa ggcggcaaat aaaagtgcat
     1021 tatctgaaaa agagatctta gataaatacc agaatatata cggtgctgct gatgtcaaag
     1081 gacttcagat atcgaatcta aaagtagata aaaaagacga ttctacttac agtttttcat
     1141 ataaagcaaa gatgaatacc tcattaggtg aattgaaaga tctttcttat aaaggaacat
     1201 tagacagaaa tgatggtcaa accacgatca actggcaacc caacttggtt tttccagaaa
     1261 tggaaggaaa tgacaaagta agcctgacca cacaagaagc agcaagaggg aatattatag
     1321 atcgaaatgg tgaaccatta gcaacaacag gcaaactaaa acaattagga gtcgttccaa
     1381 gtaaacttgg agatggaggc gaaaaaacag ccaatatcaa agcgattgct tcctccttcg
     1441 acttaacaga agatgctatc aatcaggcga tttcacaaag ctgggtacaa cccgattact
     1501 ttgtcccatt gaaaatcatt gatggagcaa cgccagaact tccagctgga gctaccattc
     1561 aagaagtaga cggcagatat tatcctttgg gtgaagcagc tgctcagctg attggttacg
     1621 tgggagatat cacagcagaa gatattgata agaatccaga attaagcagt aatggaaaaa
     1681 tcggtcgctc aggtttggag atggcttttg ataaggatct tcgtgggaca acaggtggga
     1741 aattaagcat tacagatgca gacggtgtag agaaaaaagt tctgatcgaa catgaagttc
     1801 aaaatggcaa agatatcaaa ttgacaatcg atgcgaaggc acaaaaaaca gcttttgaca
     1861 gtctaggagg aaaagctgga tcaactgttg cgacaacgcc aaaaaccggt gatcttcttg
     1921 cgcttgctag ctctccaagc tatgatccaa acaaaatgac aaacgggatc tcacaagaag
     1981 attacaaagc ttatgaagaa aatcctgaac atccattcat cagccgattt gcgacaggtt
     2041 atgctcctgg atctacgttt aaaataatta cagcagcaat cggtctcgac aacggcacta
     2101 tcgatccaaa tgaagtgttg acgatcaacg ggcttaaatg gcaaaaagac agttcttggg
     2161 gatcttttca aacaacgcgt gtcagtagtg atgtatcaca agtagactta aaaactgctt
     2221 tgatctattc cgataatata tatgcggcac aagaaacgtt gaaaatgggt gagaaaaaat
     2281 ttcgtacagg cttagataaa ttcatttttg gtgaagacct tgatttgcca attagtatga
     2341 atccagcaca aatttctaat gaagatagct ttaactcaga tatcttgcta gctgatactg
     2401 gatatggaca gggcgaactt ctaattaatc ctatccagca agcagcaatg tattctgttt
     2461 ttaccaacaa tggcacactt gtctatccta aattgattgc agataaagag acaaaagata
     2521 agaagaatgt catcagcgaa acagcagtac aaacgatcgt gccagatctg agagaagttg
     2581 tgcaagatgt aaatggtaca gcacattctc tttctgcttt agggattccg ttggcagcga
     2641 aaactggtac agcggaaatc aaagaaaaac aggatgtaaa ggggcaagag aacagtttct
     2701 tgtttgcttt caatcttgat aaccaaggtt atatgatggt cagcatgttg gaaaataaag
     2761 aagatgatga ttcagcaacc aaacgagcat cggaactatt gcaatacctc aaccaaaatt
     2821 atcaataaaa aattgctttt taagtacagt aaaaggactg tggcgttatc gtcacagtcc
     2881 ttttttcaaa taaacggttt tcacgatgtc tctttcacaa cttctttttg atttactcac
     2941 acttcataaa ctttttttgt aaaatatttg agaacaagtg gagaaataag tgtacttaat
     3001 aaaatcacga taactaaagg tgaatagtac tgtggttcga tcaattgact ttgctgtcca
     3061 atttgtaaaa tgatcaaagc catttctcca cgcgaaatca taccagcacc gaccatcaat
     3121 gaactatgtt gagaaaaacc ggcaatctga gcaccaaaat aacctccaag caatttggtc
     3181 aaaatcgcta caagcgtcaa tatagaaata aagagtagtt gttcactaaa gtcagaaaaa
     3241 tcaacttcta atcctacact gacaaaaaat actggtataa atactgcata tcctaaagcc
     3301 tctacattgt ggtatacttc ttctttaacc tttgtctgac tgacagctat cccagcaaaa
     3361 aaagcaccaa tgacagagct aagcccaaca agatccgcta cgtaagacat tcctaaacaa
     3421 ataactagcg atacgatgat aatagaagaa tttgcgtaca ctttttctgc aaatgaaagt
     3481 aggaaaggcg caatccattt gactaataag aaaataaaaa caaaataaat tagctgttca
     3541 atcaaaacaa gcggtaaaga agcattgcta gaagcttccc ccgttagaaa agataggctg
     3601 aaacttagaa ctaaaacgac taaaatgtca tctaccacag aagcacccaa aattgttgat
     3661 ccttcttttg tattcactac gtttagttct tttaatactt ctactgaaat actgacagaa
     3721 gttgccgcaa gaataatccc aaagaaaatc gcttcatttc ccgaaacttg gaatgctttg
     3781 cctgtcaacc agccaaaaac aaccgggaag atgatcccaa gcaaagcaac gaacatacca
     3841 ggtcggaaat attttttcaa aagagataaa tcactttcca gaccagctaa aaacattaat
     3901 aagatcacac caatctccga aaagtcatgg actagaatat caggtttgac ccaattcaat
     3961 ccagcttggc ctagcaaaac accaacaagt aattgtccaa tcactgctgg gatacctaat
     4021 ctccgcgaga tatgtgagcc aatcgttgtt gaaatcaata tcaggcataa aataccaata
     4081 aattccattc tcatcattcc tttgtataaa atatagcccg aacttagcat aacatacatt
     4141 attgaaaaaa taggaaaata tactcacaaa aaaaccaaca atccaaaaga tttttttgga
     4201 ttgttggttt ttatacggtc tattttaata actaaaaatg attaacgtat agtcattttt
     4261 cttattctga tgaaattgat aatctcctgg atgcccatga aaatcaaaat aaagccgaat
     4321 atttggaata gaagcatcaa acttttgaat ggattgaaca ataagacgaa tccgccaatc
     4381 aacaacagaa tactactata aacactccaa cttttagctt ttgtattcat gctgaagaac
     4441 aactggaaca agctgttgat gataacagct aatccaagaa gaatcggcag gatagaaacg
     4501 attgcaggtg caaaagcata gacgatcaga gctaagatca ggaaaaaaag accactgaac
     4561 agaccgatac tccaagaacc tgttttcctt ttaaaacggt aagcctcaaa aagattcaac
     4621 aacccaagca aaacaagata ggcggtgatc agataaccga taaaatgaaa aacagcagaa
     4681 gggtttagca caatcgcaat cccagaaata atataaacag cagctcttaa taaggcgtat
     4741 ttttgaatat tttgtttaat cgtctcaaac atataagaaa acctcctttg acttatttta
     4801 acgtgaacta gtcattttac caaattaaat gttacaaaat gagcgaagga gaagaatatc
     4861 tctggaaaaa tcaacttctg aggatctttt ccattttttt gccttttgct agctcatcga
     4921 tcattttatc taaataacga atttctttca tcaagttatc ctcgatgtct tctactcgta
     4981 caccacaaac aacacctgta atcaaggaac gtgaaggatt ggggacaggg gcttccgcaa
     5041 aaaattgttc gaaagtcact tgtttttgta gttgatattc tagttctgtt tgggaataac
     5101 ccgtcagcca acaaatgatt tcatctactt cctcttttat acgatctttt ctctccgctt
     5161 ttgctacata cataggataa acgcttgcaa aacttgtcgt aaaaatacga ttttgcgcca
     5221 taatcagtca cctttctttt tttcaaatta tttactactt atagtatata agaaaaagag
     5281 aagaaaaagc gattattcaa aaaaacaaaa aggattgtga caaaattctt gtcaccatcc
     5341 ttttttccgc tctctgactt tttacaatct tcatagctca agtgcgcatc agataatcga
     5401 atgctcctaa agctgcagta gctcctgaac ccattgaaac aatgatttgt ttgtatggac
     5461 tatctgtaca atcaccagct gcgaaaacgc cggggatatt cgttgcgcca tttttctcgg
     5521 tcactatttc atttcttgga ttcatttcga tcgttccatc tagccaatcc gtattaggga
     5581 gtaagccgac tagaatgaat actcctgaaa cagctagtgt atgcatctcc atcgtacggc
     5641 gatcgatata ggagagagat tctacctgat tcgtaccgct gatttctttc gtcgctgcat
     5701 gtttgataac agtgacattc gcaagagaga ctagtttatc ctgtaagatt tgatctgctt
     5761 ttaattctgg taagaattct agaacatata catgttttgc taacccagcc aaatcgattg
     5821 ctgcttcaac accagaatta ccaccaccga taacagcaat ctcttttcct ttaaataaag
     5881 ggccgtcaca gtgtgggcaa taagcaattc ctttattttt aaactctttt tcgcctggta
     5941 cattgataga acgccagtgc gcacctgtcg cgatgatggc ggtttttgct ttaagtgata
     6001 taccgttagc taagccaata ttaataaaat gttgctcttt atttaaggaa acggcctgtt
     6061 gattcatcat aatgtcgata gggtaactac gcacatgact ttctacttgc tgcatcaatt
     6121 ttggaccttc tgtgtaagag gtaccaatca tattttcaat ccctagtgtt tcaacgactt
     6181 gtccgccgaa agaatcagcg acaagtcctg tacggattcc tttacgtgct gcatagatag
     6241 ctgcactact agctgctggt ccaccgccaa ttactaatac atcataaggt tctttttcaa
     6301 acaactcttc ttcaatcaaa gggccagtga ttttttcaac aatttgttcg atcgtcatgc
     6361 gtccgctact aaattcttct ccatttaaaa acacagttgg cactgccatg atttttttat
     6421 catcgatttc tttttggaac atcccacctt caatcatcgt atgagtaata tttggattta
     6481 atacagctaa tatattcaat gcctgtacaa cgtcggggca attatgacaa gtcaagctaa
     6541 cataactgtc aaaatgcaat gtttgtgtta tttttttgat tttaagactc aaagattcac
     6601 tgattttcgg tgcccgtcca ctaatttgta acatagccag taaaaaagag gaaaattcat
     6661 gaccgagggg gataccagca aaaacgattc cactttcttt gccaactgga ttgatagaaa
     6721 aactaggtgt gcgcatcgaa tctctttttt cccaagagat tttaggagac atttctgcta
     6781 tttccttcgt aaattcagct agtttttgac tattttcact attatccaaa ctaacagaaa
     6841 aaacaatagg agattcaatc agtgctaaat attgttcgag attttgttta gtttctttgt
     6901 ctaacatatc caccacctaa atctttccaa caagatcaaa acttggtttc aatgtttcgc
     6961 cactttcttt ccattttgcc ggacaaactt cacctgggtg ggtacgtaca tattgagcag
     7021 cgcgaatctt atcaatcagt gcactagcgt cacgaccgat tccatctgca ttgatttcca
     7081 tagcttgaac gattccgtct ggatcaataa taaatgttcc tcgctgagct aatccttgct
     7141 cttcatccaa aacatcaaaa atacgagaaa tctgatgaga cggatcaccg atcatcacgt
     7201 attcgatttt accgatagca tctgatgtat catgccatgc tttgtgagta aagtgggtat
     7261 cggtagagca agaaaagact tcaacaccta aagatttcaa tgtactgtat tgttcttgta
     7321 agtcttctaa ttcagtagga caaacaaaag taaaatcagc tggatagaag caaagaatac
     7381 tccagttccc cataagatct ttttcactga cttctaaaaa ttctccttga tgataagcat
     7441 gtgcattaaa ttcttcgatt tttttcccaa tcaatgacat agtaaaacct ccaataataa
     7501 ttatttattt ataattattg taatttagtt ggagttgcaa agtcaatgga tattttgtta
     7561 tttaataaag attactcaaa aacgaaggtt aattataaaa atagaagagg tcgcaagaaa
     7621 atgctactgc tggaaatact cgggataacg ttgagtaaca gtttcctgtt ctttcagcat
     7681 catgtgtaag tgcaatcccg tttgaaatcg agcttcttct ggttttttat caactaaagc
     7741 cttgagtaaa tcataatgtt gttccatgat cgtttcccat ggaagcccct gaatggtcac
     7801 tcgtaaccag cggaaacgtt ctaaatgggt attatggtca tctaaccagt tccaaacttc
     7861 ttttcttcct gcaatttcga aacaagcttc atgaaataaa ttatctgcac ggaaaaaagc
     7921 gcgttcgtca tttattttga ctgctttttc ttgttcttct aaaatcgttt ctagcactat
     7981 tcgtgtttgt gtgtccaatt tggaacaaca ttcaatcatg atttgctctt ccaactgttc
     8041 tcggacaaag cgagcatttt ctgcagaaac aagattaatt ttggaaacat acgtaccact
     8101 ttgaggtatc gtatacacga gttcttgctg acgtagttga atcaatgctt cgcgaatggg
     8161 agtccggccg atagcaagat gttcctccag tgccttttca gatattttcc ttccaggttc
     8221 taagtcagca tagataattt gtttacgaat cgcttgataa gcttgtgatt gcgagctgct
     8281 tttcatcttt attcctccaa aatcatttct atgaacgtag tataacagaa gaggtctgaa
     8341 aaacaatctg gtatgtcaca ttaactagta aatttgtata aatagtaaaa ttttggttga
     8401 catagcgatt tttattgtat aaaattcact tgaatacaaa aactaatatg ttagtttagg
     8461 aggggaaaaa tgattgattt aaacaactgg aggaacttta tccctgaatt atctcaaaaa
     8521 gaagtagaaa tacctcattt tgaccgtgca tcattaagag aaaatggaca aaaaaatcct
     8581 gtctggatcc atttcggtgg cggaaatctt tatcgaggat ttcatgcaga aatcgctcaa
     8641 cgtttagcgg atctaggcga attgtccact ggtgtcattg tttgtgaaac attcgatgaa
     8701 gaaataattg aaagggctta ccaagatttt gatgatttga ttcttgaagt ggtcatgcca
     8761 agcagtggag agttcgtcaa acgtatatta gctgcgacag ctgacagtct gtattgtcat
     8821 ccagattgtt ctgaacactt tgataagatg attcgacact ttgaaaatcc tagtttacaa
     8881 ttagttactt ttgctattac tgaaaaaggt tatcgattga aagatacaaa taataaatat
     8941 ataggaccga ttgcagtcga tataaaaaat ggtccaaaga agccatcaca tacaatgagt
     9001 attcttgctg cgctacttta taaacgtttt ttatctggag cttggccgat tgcacttgtc
     9061 tctacagata atttttcaca aaacggtagt caattacgta cttctttgct aacgatcgca
     9121 aaagaatggc aaaaggaagg ttatgtacaa aatacattta tccaatactt atcgaatgaa
     9181 gaaattgttg cgtttccatg gacgatgatt gatcgtatca ccccgaatcc ttccttgtca
     9241 gttagcaaaa tgttggcaaa agagggcttt tcaaatatgt cgattttcca aaccgcaaaa
     9301 ggaaataata ttgctccatt tgtcaataca gaggacatcc attatttaat catggaagat
     9361 cattttccca atggacgtcc gaaattcgaa aaagctgggg tattcttgac tgatcgtgca
     9421 acggtagata aagcagatac gatgaaggtg acgacttgcc ttaatccttt gcatacgtct
     9481 ttagctatta tgggttgttt actggggtat aggagcatag ctgaggagat gaaagatcca
     9541 gatttatcgc tgctagtttc tgaaatcggg tacaatgaag gcctcccagt tgtggagtct
     9601 ccaggtatca ttgatccaaa gatctttctg gaagaagtaa ttactgtgcg cttttctaat
     9661 ccaaatattc ctgatatgcc tcagcgaatc gccacggata cctctcaaaa ggtggcgatt
     9721 cgttatggtg agacgattaa aaaatatatg gaaatagaag ttaaagaccc gcagacactt
     9781 gtattcatac cattgactct cgctgcttgg cttcgatacc ttattggcat tgatgatcaa
     9841 ggaaaaccat tcatcccgag tccagaccca ctattgacag actttcagca taagctttcc
     9901 gatattcaac tgggtacgca agatacatca catattcatg agaaaatggc tcctattttg
     9961 tcaaataaag aaatttttgg tgtagatctt taccaagcag agcttggcag aaaaatagaa
    10021 gaaatgttca tcaagatggt agcaggaccg aatgccgtac gaaaaacatt acaggattac
    10081 ttacaagaac atggaggaaa tttatcatgg aaatgacttt tagatggtac ggatcacagg
    10141 aagaaaagat taccttagat gaaatcagac agattcctgc ggtcaaaggg attgtaggca
    10201 cattgatgga tataccagta ggagaggtat ggcccaggga gaggatcaaa gaactaaaag
    10261 aagaaattga gtctcgtggg ttaacactaa aagtaattga aagcgtcaat gtgcatgatg
    10321 ccattaaaat tggattacct tcccgtgagc agtatatcga aaactataag cagacaatcc
    10381 gaaacttggc agaatatgga atagaagtca tctgctataa ttttatgcct gtatttgact
    10441 gggtgaaatc tgaccttgac taccgcttag aagacggctc atccacgtta gcttttatat
    10501 ctgatgatat tccagatgat ccaagagaaa tcgtcgcgcg catcgaacat tccagcaatg
    10561 aatttgaatt gccgggatgg gaacctgagc gcttagctca tatcaaatcc ttgcttgaag
    10621 cctatgcatc agtagacgaa gaaaaacttc gagaaaattt tgcctatttt ctccaatcaa
    10681 tcatcccaac atgtgaagag gtaggggtca aaatggctgt acatccagat gatccgccat
    10741 actcgatttt tggattacct cgaatcgtaa agaatcgaga agatttagat tggttgtgcc
    10801 gcatagtaga cagcccttat aacggaatca ctctttgtac agggagtatt gcagaagatc
    10861 cagaaaatga tgtatatggg attttagcag aattttgtca aagagatcga atcccatttg
    10921 cacatgttcg aaatattaaa tttttagcta atcgagattt ctatgaggca ccgcataaat
    10981 ccgaatacgg ttcattagac atgtaccgca tactaaaaac aatgtatgac aacggattta
    11041 acgaatacat ccgtcctgat catggaagaa tgatctggaa tgagacagga agaccaggat
    11101 acggcttata tgatcgagca ttaggtgctg tttatctaaa tggattatgg gaagcaatcg
    11161 aaaaaggaaa caaaagtaaa gataattagt gaaaaaaact gtaattttat tatgtaaata
    11221 agaaggatgt tcaaattctt gatacataaa tccggaggtt gttaataagc attcggattt
    11281 atgtatctta tttggtctag gaagtaactt gattttcttt tttcgattga tccatgagtg
    11341 cttcttcttt taattcaaag atatattctg agatcctcat aatcactttt ttccagtctt
    11401 ctggtgtgat gattcctttt aaaatataga tttttttgat atgagaaggc aattgtttca
    11461 aagggcagtc gctgataacg atgttgcagt tctccataaa atcattttgt attttgatcg
    11521 attcatttga aaaaatttgt tctatcttaa cgatcagatc tttactgata taaaaatcac
    11581 gcgtatagtt cacaccaatc acaattcgcg gctgtttttt gtagcgatca tacaaatgta
    11641 ctaggtcttc aaccatccat tgcacatttt ccttttctaa aataactggt aacaagtgtt
    11701 gattttgttc tctgaaatcc atataaaatt gttcaatggc ggtttggact tctttcaaca
    11761 cgctatgttc ttgataaagc atgaaagtag gaaggggcgt atttggttga ttgaagttaa
    11821 gaaatccatt ataaagttta tttcgtgcga atgccaatga gtaaagaatc ttttcttttt
    11881 caggtataaa caaatcaaat acagtacaaa aggactccac catttctctt gaataaagaa
    11941 catgaggaac gtttgctttt tttaaaagtt tgtattgctc caagcttgtt tcttccgatt
    12001 cgattttcgt gatagaaagt cgagctaaaa tattcactaa gatgcgttgt tcgcgacaaa
    12061 ttggcagatt aggtcgcaaa atatctacag agggatcaat aaaaaagtca atatattcat
    12121 actctgtgaa ttctttttgt acgtctttca cagaagttgc aggaaaattc tctttacata
    12181 tttttaatag aaaatataat ttatctatca taccgctatt tagtcggtca agtacttctt
    12241 ttttaaaaaa agtattcatc ataaaagcca ctacttgcgg atcttcatca taaaattctg
    12301 tagcagtact tgaaaagatg ttccaataaa tatctaatgc tgcatattga atttgtacct
    12361 cttttccaga aaaagacttt ctgccattat tagaaaagga gatagacaaa ccgtacaatg
    12421 ctaaaaatgc attaatcttt ttcattttcg tatacaaata agaggcacta tagtttgttt
    12481 gctgacttaa actgataatc gaatttgtct gacagctgaa caaagaagtc aagatctgat
    12541 aactgactga ttcgttgcag tatcttccaa atagacgata atagcagtaa gccggatcaa
    12601 ttccttcaaa attcaacttt aaaaaaggtt tttgcttatc aatatgcagt tctgttagat
    12661 tgagacgctc aaagtcttgt tctaattctt tgatgtatag taaaaaattt gattcagaca
    12721 tatggaaatg atctgctaaa tattgtgtag taataaagaa acgatgttca gataggaaaa
    12781 gaaaaatatc taattttgta ttgctttttt tcttcaagag aaacgtttta atcgcttctt
    12841 gagtttgcat gaaagaggct cctttttact taaattgtta aaacttgaaa atattactgt
    12901 ttttttcata aatttagaca aaaaaacagt aaacatatag gtagaatctc tactatctta
    12961 tttcttgcat acaaaaaaat caaggagtga gagagttatg agatattcaa ccatcttaat
    13021 atcaacattt gcagccttaa gcttatcgct tactataaat cagacagtcc acacagagga
    13081 gatagaaaca gccaaatgga cagaaaccaa gtgggccaac gtcaatcgaa ttacctttca
    13141 ggatgaattt tcatccttca attcaggagt cgcaaaatta agaaaaggac aaacagcgac
    13201 catcaaagca aaaattgact attcaggaga cttagcacct atactacaat cagctgttac
    13261 atttgagaat gttgatcccg ctttgtcgat tggctatgac gagaacactt tgactatcca
    13321 acacaagcaa gcgatattta ccttcaccgt tacattaaat caggacttgt taaaaccagc
    13381 gctttttact gtcaaggtat cagatggact accgaacgat catcatcatt taacgccgta
    13441 tagtcagcgg cagacaattg agcaagattc agctatcgac tcaggaggag atcttgttga
    13501 agaaccaaca gataaaccag aaaatgaaaa taagccagaa gtaccgccta cagaaaatcc
    13561 agacggagaa cagaaaccgg aaatagaacc tggagaagaa cccgatacag aaactcaacc
    13621 agagccagac aatgaatcaa aacctgaaat aacccctgga gaaaaaccag atgtagaccc
    13681 agaagaaaaa ccagatgtga ctccagaacc agatacggat tctggaaacc aaacagtacc
    13741 ggaaacaaat ccagacacag ataatgaaac tgaaaatcca gaaaaaccag aggtagcccc
    13801 agaagaaaaa ccagatgtaa ctccagaacc agatacggat tctggaaacc aaacagtacc
    13861 ggaaacaaat ccagacacag ataatgaaac tgaaaatcca gaaaaaccag aggtagatcc
    13921 agaagaaaaa ccagatgtga ctccagaacc agatacggac gcaagagacc aaggaatacc
    13981 agaaaaaata aacaaaaaaa caattcaaga ggatggaaaa aaagagagta aaaaatcaaa
    14041 tctagcaatt ctaaaaataa atgaagagca gctgaataaa aaatcacgaa tatttgatag
    14101 cgcccaatca gctgaaacct taaaaagtag caaggataca acctttgctg tcctgaaacg
    14161 aaaaataaac agctaccaaa atccggagag tcacaaaaca aagttatact gtggagcgga
    14221 atcattctat taagtatagc aacaatgctt tctgcaaaaa gatttaaaca aaacagatct
    14281 ctctaacatt tgaataatgt ctgtgaacgc atttttcaaa taaaaagaaa tatccagaaa
    14341 atgaccccaa aataccagat tgaaatctga tatttggggt cgttcatact ttatctttct
    14401 tcatatttat tttaagggat atctgtttct tttggaagat ggttcgggat ctttttcact
    14461 ttcaatacat ctaaaaagaa ggtaaagatc ggaatgccga caatcaagcc ccaaacgcca
    14521 aagaaccgtt cgctaacaag taagaccaca aatgtataaa aaatcggcag ttctgttttg
    14581 ctggacatca acttcggatt cagcacataa gactcaatta gatggacaat caaaatcgta
    14641 atcaggatat aaacaacatc tcggatgcct ccttgggaat aagctatgaa agatagagga
    14701 atacaagaaa tgataacacc tgctactggg atcagactta aaatgaaaat catgatcgct
    14761 aaactcagca gctgatgaaa gccaaataca gccaaggcga ttgtagtgag caacgtattt
    14821 aaaagagcga caacaaattg agcttctaat accaaaccaa atgtattgac aaacttatcg
    14881 gcaaaatagt aaatatcttg aaagaaccaa gaaaattcac tttttaaaaa caatcttgag
    14941 aatacaattg tttttttctt ttcaatcata aaaaagaaac ttaagatgaa tgacatagca
    15001 aacgccactg ccatttttcc tatatcctgt aaatagccaa gcgcaatcga agcgccattt
    15061 tgaagctgtt caaaaaaatc gtttcgctca atataagtat ggatatattg taaaacagga
    15121 tctgcatctt ttggctgatg ctcgtaaaaa ttaataacgg actggatcat gtcaaatgtt
    15181 tgatgaataa gcatcgggat atactttgtg aatgccagat agataaggta aacgatcagt
    15241 gtataaatca tgatagctaa aacacctgta gggattcgga caaatcgctg aatgatttga
    15301 acaagatgaa tcatcaaata agtaaagata aatgtgagca aaatggttgt aatcatactt
    15361 ctaactaaga aaagaacaaa aacgacaaat aataaaacag tgagacggcg tattttttca
    15421 ttcgccaaaa aacgctgata aacggtcaaa tcgacaacct ccaaataaca aaaaataaac
    15481 acgttattca ttatatgatg gaatatgaaa ataagaaaga gcaaaaagaa aaaccgctaa
    15541 atgacgttat cttatgagtt ggttttcctc ataaaatcgt tcatctagca gtttcagccc
    15601 tttttctggt cttgatgaaa attatctagc atttttcggg tcagatgttg cagtgtatcc
    15661 aattcttcct gttcaagtgg aagataagac ttgatctttt gtggaatacc ttctgcttgt
    15721 ttttgcaacg cagcaccttg agcagtcagc gtaacattta cgattctttc atcacccgtt
    15781 tcacgctgac gattaatata atttttttct gctaactttt ttagtaaggg agtcagcgta
    15841 ccagaatcca gacacaaatc atttcctagc tctttcactg aagtcttttt cttttcccat
    15901 aaaactaaca tcacaagata ctgggtatag gtaagattca gcggcttgag gaggggagtg
    15961 tagtgtctaa tgatttcttt agaggcggca tataaaggaa aacatacttg attaactaaa
    16021 tatagatctt ccatttttcc acctccgctg ttttactata gtgtatcata gcggatttac
    16081 acaaaaaagt ctattcacta actgctttca gagtaacttc tatatttcca gctgtagctt
    16141 ttgaatacgg acacacttta tgcgctgcct ctaataattc ttgcgtttct tccagagaaa
    16201 gaccttcgat agatccttca atctctacac ctaagacaaa gctcgtttca ctttctgaat
    16261 aaagggaaac ttgtgcactg acagtagaag ccccagagat atttttttgc tgtttgatca
    16321 attctaatgc actgttaaaa catgcactga aaccagctgc aaacaattgt tcagggttgg
    16381 ttgcattttc gacgcgttta ccaggagctg caatattcaa ttcgaatgta cgatcgggat
    16441 tatgcacttc tccagagcgt ccgcctgtgt tgatcatttt cgtagaatac atttttttca
    16501 taaaattacc acctttaatt atattttata caattgaatt ttacacaata taattgtgga
    16561 aagcaaagaa atggattggc ataagataaa taagagaaag cacatgaaac agacgcgctt
    16621 tctcgaatag caaacatata caaaaaatat cagagacaaa aaataatctc atcataaaca
    16681 ttacatatat ttctcaaaaa gttgttttct ttcttcaaaa attacttcac gatggacctg
    16741 atgaagcatc cataaataac caaaaggatc tctgaacatt gagttagtca caccaaagtc
    16801 catcatttct gtcatttctt gaatctctac acagccattt cgtaatgctt tattatgtgt
    16861 gtcctcgata tcagagacga tgatattgaa ccagatcgta tttggatgtt cagcagtagg
    16921 agcagtcaaa ccaagagacg tgttttcatc cagcatatgg aatctcgtac catacaaggt
    16981 aaaaatgact tcattattgc ctctagggta atctgttgcc tcaatcagtt gtatttcatc
    17041 aaagattgtt tgatacagtt ctagtgcttt caaactatca tttaatacaa aatcgatttc
    17101 cgttccttta tgcataaaga tctcctctcc ttttcagtcg aacagttact agattctttt
    17161 attataccag ctaaagaaaa cgcattcaaa aaaatagcgg atttacttac caactcattc
    17221 gattggatga taagtaaatc cgcgtcccat tacttctgct acgctgctga caatgacaaa
    17281 ggcacttgga tcgatttctt ctatcaatgg tttcattcgg gaaaattcat gatcagtcac
    17341 aacgatcaat aaaacctctt ttgactttcg attatacccg ccttttgcct ctagcagggt
    17401 aaggccacgt ccaatctcag cacttaagcg aaggcggatg tcttccaaat aatgttcact
    17461 catgaccata acagatttct ttcgattgat acctgtttcg atataagtca tgacaattga
    17521 agtgattgca atagataaaa tagcataaag aaactcttct attccaaaaa taaacagatt
    17581 aagagaaaca acgaatgcgt ctgtaaaaaa taagccaatc gaagtattca agtggaaata
    17641 ttttttaaaa atgaggggag ggatcgtcgt accgccgcta gaagagttgt ttttatataa
    17701 aatcgcaact cctaaagcaa aaatcgcact tccaaaaatg acagacaaca accgatctga
    17761 agtaatcatt gtttctggaa ctattgcaat gattaaagga aaaaccaagc ttccgaaaag
    17821 tactttaaaa aagggttttt tacctaaaaa tagaagagct agtaccaaca taacgatatt
    17881 caacactaaa ataactatag ctcggtcaaa gcctaaagca gcttccagta atattcctag
    17941 accgctgaca cctccagcag caatatgatg aggccctaaa aacatattga tagcgactcc
    18001 taatatgaag agggcaaaaa taatcttaat gtatgtccat ataaattgtc tcgtttcttt
    18061 catttattca cttccttaat tcattaataa tactcttatc ttattataac ttacttttca
    18121 ccttaagtta actttaatta ataaaaaaat taggctagtc taaattatta tgtttcattc
    18181 ttctagaata tacttctacg ccaaaaactg ttaaaaaact tttactttag aaaattggag
    18241 aaattgatcg cttaagataa attcaggaca ctaaatagta caggaagtag actaaaactt
    18301 ttaaaagttt taagtctatc tatttggcaa gtttaaaaaa taaaaattcg gtatcaaaaa
    18361 actgttaccg ataacatttt tgaaagcgtt gtcttttgct tctctatcac ttatagtgat
    18421 gacgtcatat taaaacacaa ggaggaaatc aatggataca gctgcaattt atcatcgacc
    18481 ggaaagtgaa tatgcatttc tatatacgaa tacaagattt cgtattcggc ttcgtactag
    18541 gaaaaatgat atcaaaaaag tatatgtgct atgtggagat ccatatacca taacaactga
    18601 aaaatggtat caaaaacaac gaccaatgaa aaaatgtcta agtaccaatg ttcatgatta
    18661 ttgggaaatt gaagtgacga gcgaaacaag tcgcttacag tatgcgttcc atgttgttgg
    18721 ggaagataac acggactgtt tttacggtga tcaaggaatt tttccttatc gagaaaatgt
    18781 gattactgaa ccaaattttt attttcgaat accttatttt catcaaatcg atcgattcac
    18841 tattccagaa tgggtaaaag aaacagtatg gtatcaaatt tttcccgaaa gatttgcaaa
    18901 cggggacaaa gcaaatgacc ccgaacacac tttaccttgg ggaagtaaag atccagaccg
    18961 agaagacttt ttcgggggag atttgcaagg tgtgatggat catttggatt acttgacgga
    19021 ccttggcatc aatggcatct atttttgtcc catatttaaa gccacatcca atcataaata
    19081 cgatacgatt gattattatg aggtggatcc cgcttttggc gataaaaaac ttttaaaaaa
    19141 cttgattgat gaagcacata aaagagggat acgtatcatg ttcgatgctg tattcaatca
    19201 tatgggtgtc cattcaccac agtggcaaga cgttctcaaa aacggagaaa aatcgatcta
    19261 taaagactgg ttccacatcc gttttttccc agtagattct tatcagatga ctgacttacc
    19321 agaaactgct gaaaatatcc catatgatac ttttgctttt actccattca tgccgaaact
    19381 aaatacagca aatccagaag tgcaaaaata tttgctggat atcgcaactt attggataaa
    19441 agaattcgat attgatggat ggcgtcttga tgttgctaat gaagtcgatc atcatttttg
    19501 gaaaaaattc agagaagcag ttacagaaat caaaccagac atctatatcc ttggagagat
    19561 ttggcattcc tctcaagctt ggctgcaagg ggatgaattc catgcagtga tgaattatgc
    19621 atttacagat tcgattaaag attattttgc aaaaaagaaa atcacagctt cacaaatggt
    19681 cagtggaatg aatcatcagc aaatgcttta cagagatcag gtgaacgaag gaacattcaa
    19741 cttattagat tctcatgata ctgccaggat cttgaccctt tgccaaggta acaaagaatt
    19801 gatgaagtct gtgatggcct ttatgtttct tcaaaaaggg tctccttgta tctattacgg
    19861 gacagaaata gggatgactg gtgaagatga cccggattgc cgcaaatgta tgatatggga
    19921 gaaggaggaa caagatctag agctattcgg ttttataaaa gaacttgttt ctctaaggaa
    19981 acagttgtct aagattattt ctgaaggttc tactcagtgg ctaatagtaa atgatcgtga
    20041 agataagctc tatttcacac ggaaactaga gggacagatc atctatgttt actttaatca
    20101 gtcaaaagaa ccttgggtag tagaacagga aaatgaggtg attcttagtc aaaattgtca
    20161 gttgttagaa gacgggaaag cagagatacg acaatacgga tttttgatca tgtgttgaaa
    20221 actgttaccg gtaacaacaa gaaagcgttt gcaaatgaag atttgtgccc attataataa
    20281 gggtgtaaca gcacgttgaa tacaaaggag gaaatgaaga tgaaaaaaag aagtgtgaaa
    20341 cagttgggtt tagggttaat ctctttagga atcttaggcg gattagcggc ttgtggcaat
    20401 ggtaactctt cagcagaagg ggaagccgat gaaggaaaaa cgttaacagt ttccgttgat
    20461 tctggatata aagattatat aaacgaaata aaaaacactt tcgaaaaaga aaacgatgtg
    20521 aaaatcaagc tagtagaaaa ggacatgttc gatcagttgg aatcattagc gttagatggg
    20581 cctgctggaa agggacctga cgttatgatg gcagcatatg accggatcgg tgcgttagga
    20641 cagcaaggac atctggcgga agtaaaactg ggaaatgaag cagcttacga tgaaacagac
    20701 aaagcccaag tgacttatga tggaaaaatc tacggagaac ctgcagtaat cgagaccctt
    20761 gttttgtact ataacaaaga tttagtcgat acagcaccat caacgtttaa agatttggag
    20821 aatctatcca aagacagtcg ttttgctttt gagtcagaag caggaaaaaa tacaggattt
    20881 ttagctaaat ggactgactt ttattattcc tatggtttaa ttgcaggtta cggtggctat
    20941 gtatttggtg atgatggcac aaatccttca gatatcggtt tgaataatgc aggtgctgta
    21001 gaaggaatct cttatgcaac agattggttc aaaaatgttt ggccaaaggg aatgcaagac
    21061 ataaaaagtg caggagactt cgccagccag caattcatgt ccaataaaac tgcagcaatc
    21121 attgacggtc catggcaagc gcaaacatac aaagaaaaca atatcaatta tggtgtagcc
    21181 aaaattccta ctctaaataa tggacagcct tatcaaccgt ttggcggagg aaaaggatgg
    21241 gtagtcagca attatgctaa aaacaaagac ctctctcaaa aatggcttga ttatgtaacg
    21301 aatcaggaaa atcaagaaaa attctttgaa atggtaaatg aaatccctgc aaaccaacaa
    21361 gctagggaaa cagcaaaggc taaaaacgat gaattaacaa cagctgtgat tgaacaatat
    21421 gaaacagctc aagcgatgcc aaacatccca gaaatgggcg aagtttggac aggtgcagaa
    21481 aacttgatgt tcgatgcagc atcaggttca aaaacaccaa aagaatccgc agatgaagca
    21541 gtaaaaacaa tcagtgaagc catagaacaa aaatactgat taaaatgata accgtccatt
    21601 tttataaaaa atggaacagg tgcttcagat aaaagtggca agagcgagat ggaaaattat
    21661 cttgctcttg ttgccattat cttaaaagca gtttgcggtt tagcaagttt agagggggca
    21721 ttcagatgca gcaagataaa acaagcaata tcaacgaaaa aaaaatcacg ctttgttcac
    21781 ttattccagg gatggggcag tttgtaaatg gccaagcttt taaaggtatc gtttttttcg
    21841 ccatattcgt cctattcatt ggtcagatgc ttctgggcgg atttcatgca ttggtaggat
    21901 tggttacttt gggaagtata ccaatggaag atcattcatt atttattttg attgaaggca
    21961 ctttgcaatt catcattaca atcattttct tgatttttta cggtttgaat cttttagacg
    22021 cttatcgagt agcgaagatg cgtcaagagg gcaaaaaaat caatcggacg atgaaggaag
    22081 tcatacataa tataggtgat gaaggttttc cttatctatt gacacttccc gcttatcttc
    22141 tcatgatttt tacgatcatt ttcccagtcc tagttacatt gttcactgca tttactaatt
    22201 atgacttcaa tcatattcca ccagccagtt taattgattg ggtaggggct aaaaactttt
    22261 ttagtatctt ctttttaagc tcatatcgta atactttttt tgcagtcttt tcgtggaccg
    22321 tgatttggac tttatgtgca acaactttgc aaatcaccct tggtattctc acagcggttg
    22381 ttgctcacca gaaatttatt aaattcaaac gtattttcgg tatcattttc ttattaccat
    22441 gggcggtccc agcttttatt actatcatga gtttttcgaa tatattcaac gatagcgtag
    22501 gtgccatcaa tactcaagtg attcctttca taaaccagct tccttttgta gatatcagtg
    22561 caatctcttg gaaaacggac ccgaactgga cgaaagtagc aattatctta gtgcagggct
    22621 ggttaggatt tccctatatc tatgtgatgg ttacaggaat cttacaatcg atttcagaag
    22681 acttatatga agcagcaaaa atcgacggag caaatgcatg gcagcgcttt tcaaacatca
    22741 cgcttcctgc tgtcttccta gtggcagcgc caacatttat tacacagtat acggggaatt
    22801 tcaataattt ctccatgatc tatctgttta acaatggcgg tcccggaagc gtaggcggag
    22861 gagctggttc tactgatatt cttatttcct ggatctataa acttacgact ggaacttctc
    22921 cgcagtattc tatggcttca gcaatcacgt tgattatctc cgtcatcgtt atctgtgtgt
    22981 cattgctggt atttaaaaag acaaatgcgt tcaatatggg ggattaacaa tgaaaaaatt
    23041 tcattcgagt gctcgattcc aaaaacgact ttctcacttt tttacttact tttttctttt
    23101 aatactgtca gtcattatca tctatccgct tttgatcaca gcaagtactg ccttcaagtc
    23161 aggaaatatt gcagctttta gtttagatct ttcaagtgac tggactttag gaaactttac
    23221 tcggctattc agtgaaacac tttacgggac ttggtataaa aatacattga tcatttctgt
    23281 cctaacaatg atcgtacaag tgactgtagt aactttggcg ggctatactt atagtcgcta
    23341 tcgttttatc ggccgcaaat caagtttgat gttcttttta gtgattcaga tggtaccgac
    23401 tatggcagca ttgactgcct tttatgtcat ggctttctta ttagaagcgc tcgataagta
    23461 ctggttcttg acaatgatct atataggcgg tggaattcca atgaatactt ggctgatgaa
    23521 aggatacttt gacactgtac caatagattt agatgaatct gctaaacttg atggggcagg
    23581 gcatttcagg atttttttcc agattgtatt accgcttgtc aaaccgatgc tcgccgttca
    23641 agcattatgg gcttttatgg gaccttttgg ggatttcatg ttagctaagt tcctgcttcg
    23701 aacacctgaa aatcagactg ttgctgtcgg cttacaaaca tttatttctg atgtgacaaa
    23761 ccaaagagtc tctctttttg ctgctggggc aattttgatt gcactaccga tttgtctatt
    23821 attcttcttt ttacaaaaga actttgttac cggcctgaca tctggcggaa caaaaggata
    23881 ggagcagagt atcatgcaaa catttccgtt aaactatttt tccgcattac gtacgccaac
    23941 tcaagtgttt gcgggacgca aactattatc atggcctaaa tttttcttga tatttgtatt
    24001 tttagtttcc ttgatggtca tgcctgtgac tcttttttat gccaatcaga tccaagcgat
    24061 tccattagaa caatttctat ccgttcattc gctgatcgat gaacaaggaa cccaaaaatt
    24121 ttctgaactt gaattatctg aaactgggtt acaagcatcg caacaaacga tagctgtgac
    24181 ccctgaaatt ttggtaggtg tgtctttatc tgagaaacaa caatccgatc atggaacttt
    24241 tattgatttt gagaaggaac aatgggtgat ccaacaaaag gataaatctg gtatacgccg
    24301 ctatacgatg aattatagcc catctttcca accagattct gtacgtacgc ccgaagattt
    24361 ccaacgattt ttagaaagag aattttatgc cagtaatcgt ccaacaatca ttttatctta
    24421 tagtttaagt cttggtcttg tcctatttgt catgacgagt ctcattttat tcggggcttc
    24481 ctttttcttg tggatgacaa gaaaaagcca actttcatcc attcatacat tcaaagagag
    24541 tgcaaatttg atgctgaatg ttatgggaat aggttccatg gcagcagcag ttgtagggtt
    24601 tatccacttt gactttatct tgatgctaag tgtccaaaca acgataactg tcttgctgct
    24661 tttatgggtt tttgtcaaaa caagattcaa agataagcgt gtcgaatgac aagtttaagc
    24721 gatttatgcg acaatgaatg tgaaaaaaat gaaaaataaa gtagtttttg aaaaatttct
    24781 gaaaaaatta aacttcttag ttgattcttt tcttttttag tattaacgta atagggtagt
    24841 ttttttaagg aggaaaatca tgttagagaa aactttatac aatcaattat tttcacgttc
    24901 tttctcgctc cctgtcgaag taaattattg ggacggtaca acgaaacaat acggagatac
    24961 ggacactcct ccccaaatca aaatcaatat ccatgaagaa atcccaatga aagagattac
    25021 aagtaacgct tctttggcac taggagaagc ctatatggat catcgaatcg agatcgaggg
    25081 aagtatccaa gcattgatca acgatgctta tcagcaagca aacagctttt tacgaggaaa
    25141 agattatcta aaatggctgc caaagaaaga aaaacatacg aaacaaaaaa acaaagaaga
    25201 tatccatgcg cattatgact taggtaacga cttttataaa ctttggctag atccaacttt
    25261 gacttattct tgtgcttatt tcaatacacc tgaagatacg ttggaacaag cacaaatcaa
    25321 taaagtccat catatcttag acaaactctt tatcaaagaa ggcgaaacgt tgcttgatat
    25381 cggttgtggc tggggaacat tgatgttcac tgctaccaaa gagtataatg tcaaggcaac
    25441 tgggatcaca ctaagtgaag aacaatacga tttgattacc aaaagaataa aagaagaaca
    25501 tttagaagat aaatgccgtg tattattaat ggattaccgc gaactaaaag gcgaaacgtt
    25561 tgatcatatc acaagtgtag gtatgttcga acatgtaggt tctgaaaatc ttgaaggtta
    25621 tttcaaagtg gtaaaagatt tattgaaacc aaaaggaaca gctttgatcc atggaatcag
    25681 ccgacaacaa ggcggtgcga caaatgcttg gatcaataaa tatattttcc ctggcggtta
    25741 tgtccctggt gttactgaat tagttgataa tattacaaaa aacgatttgc aactgattga
    25801 tttggaaagc ttacgtcgtg actaccaatt gacattagaa cattggacaa agaattttca
    25861 tcaagtccaa gatcaagtca cgaaagaaat gggtgattcc ttctatcgaa tgtgggatct
    25921 atatttacaa gcttgtgcag cttcatttga atcaagtaat atcgatgtga ttcaatattt
    25981 gcttgttcaa cctggaaaca atgacatccc aatgcatcgt gcataattga ggcaaaagta
    26041 ctgtttaaag actatttaaa aagaagctaa gttttatgat gctccagaag tgaacttttt
    26101 tgtctaactt ctaggattgt ctctaaagct tagtttcttt ttctttatat tttcataata
    26161 aaagtttggt tctttaattt ttaaacatga cagaaaattt tttcttcgtt atacttgtaa
    26221 tagaatacta ttttataaca aaggggatcg aatcaatgaa aaaaactgtt atttatacta
    26281 gtttatttgc agctttgttt ttagctgctt gtcaatcaaa taccaatcaa ggcacatctg
    26341 ggaatacgtc ttccagtagc gaacagcgct cttcacaggt atcggactcc tcaacaaaag
    26401 caagcacatc ttcgtctagc cagacaaaaa gttctagtga agcaagtact cagtcagata
    26461 tcaaagtgtc tgcagctcgt gcgatcgaat tgttccaaga taaataccca gatactgcaa
    26521 ttactagttt ggaattagat agtgattggg gatcttactt ctacaagata gaaggtgtcg
    26581 atgatcaaaa agaatacgaa gcaagaattg atgctcaaaa tgaaaaaatg gagacagaga
    26641 atccagaaac tctagatcga gatgaacaaa atggtcaaaa gaaaaaagaa gatggtctgg
    26701 atgttgataa attgatcacg attgaggaag cagcaaaaat cgccgtcgac aaagtaggaa
    26761 gcggtacggc aacagattgg gatttggata aagatttagg tactacttat tgggaagtca
    26821 aagtaaaaga cggcaatcaa agtacatcag tcaagatcaa tagccaaaca ggcgaagtac
    26881 tgtcaactga acaagatgat taagaatttc ttcggaaaac aagagttgat ttttctttta
    26941 gtcatgatac actagacaaa ataacttgtt tgaaggagcg atttacttga gtttagaaac
    27001 gacctttgcc aatcatatct ttgccaatcc tttgatgaat gcatctggtg tccactgcat
    27061 gactacccag gaattagatg aactggctca ttcagaagca ggagcattta tcactaagag
    27121 ctgtacgatc aatgaacgaa aaggaaatcc cgaaccacgc tattttgatg ttcctttagg
    27181 gagtatcaat tctatgggac ttccaaactt aggtttttct tattatctag agtatgctct
    27241 tgcgtatgaa aaagtgcagg aaaaccaaaa tcaaccgtta tttttttcca ttgccgggat
    27301 gagtgtccag gaaaacttgg aaatgcttga gaaaatagaa aaaagtgggt ttaatgggat
    27361 cactgaatta aatttatctt gtcccaatgt gcctggaaaa ccacaactag cttacgattt
    27421 tgaggccact tatgaaacac tgaaagaagt attcagcatc ttttctaagc cgctaggaat
    27481 caaattgcct ccttattttg attttgctca ttttgatcag atggctgata tcttgaatca
    27541 gtttccattg acctatgtca atgctatcaa cagtgtgggc aatggtttgt atatcgatac
    27601 agaacaagaa gcagtagtca tcaaaccaaa agaagggttc ggcggcattg gcggagagta
    27661 tatcaagccg actgctttgg cgaatgttcg cgctttttat acacgtttga aaccagaaat
    27721 ccaaatcatt ggtacaggtg ggattcggac aggacaagat gcatttgaac atctgctatg
    27781 tggcgcaagc atgttacaga ttggtaccga gcttcataaa gaagggccgg aaattttttc
    27841 tagaatcata aaagaattaa cgcagattat gtcagaaaaa ggatatacgt caattgacga
    27901 atttaaaggc aaattacgca ccatttcata gcaaagagac gaaggtcatg attgatcttc
    27961 gtcttttttt ataaaaaaca ctcgtctgtt cattcctgtg caagcgtact cattgtatgt
    28021 tagacgaact tgtgggaaaa taacagaggc aaaaaggagg ataatatgaa tgatgcaaca
    28081 gaattagcaa aagagcttaa agaaaaagaa tttagttttc aagaactagt tacggatata
    28141 cagaaaaaaa taaagaagca aaatcatgaa ttgaatgcgt ttgtcgcgct tgaaccattc
    28201 gagagtaatt cccacgagct attgattccc cagtcagaaa aagggccatt ggctggtatc
    28261 ccatttcctt taaaaatgct cggtcaagaa aaaaagggat ggctagctac ttcaggatct
    28321 cgtttatttg aaacacaccg agcttctcat acatctaatt atgtgcggca agcagaagcg
    28381 ataggtctag ttccttttgg acaaaccaat gcgccagagt ttggtttcaa aaatattaca
    28441 gacccagtca tctatggccc agcaagaaac ccttggaacc ttgaatgtac accgggcgga
    28501 tcaagtggag gagctgctgc tgcagtttca tcaggaatcg ttcctttagc tggtgctagt
    28561 gatggcggtg gttctattag aatacccgct tcgttttgcg gattgattgg gctgaaacct
    28621 tcgcgaggga cgatgccagt tggtccatat gcttggagag gatggcaagg agctgctatt
    28681 gatttcggct tgacagtttc tatgagagac acggaggctt tattttatgg gatgagaagt
    28741 atccattccg gtgcgccata tcaagtatcg ccagttgagt ggcaaacaca tccaagaaaa
    28801 aaacggttga agatagcttt ttgtgttgat tcaccgatcc actcacagat tagtgaagag
    28861 gcagtacttg ctgtaaaaaa agctgtagat ttccttggaa aagaagggca tgatttgaca
    28921 gagattcctt acccactaga tggtcgtaaa ctgatcacgt cttattatca gatgaatggc
    28981 gcagaaacag cagcaatgat ccgctcgatt gaaacaggca tccagcgagc tgtcagaaaa
    29041 gaagaacttg aacccatttc ttggactttg ttccaatatg gtcagaagct ctctgccgct
    29101 acttacatcg attctctgca tgtatgggat gaagcagcaa ttgtcatgga aaacctacat
    29161 caagaatacg atctattcct ttcaccaacg actgcattta ccgcccctaa aatcagcgaa
    29221 gatttgcaaa gtgatgcgat aagagcacag atggaacaca tcagtgattg ttctgaagta
    29281 gaaggtttag acgttgtttc ttccatgttt gaggagagct tgaagatcac accttataca
    29341 cagttggcta atctgactgg acaaccagca atcagcttgc ctactcattt gacaaaagaa
    29401 aacatgcctc taggaatcca atttatggct gccagaggaa gagaagattt gctatttcaa
    29461 atcggctatc tatttgaagc aaatcatcag ttccatttac caaatccatg gaaatagcag
    29521 aaacaaggag aagaagaatg aagaaaaaaa gattgtttgc tctaataact agtgcctttt
    29581 ttattttaag cgcttgcggt acagctgccg ctaatcagga agataacagc tggagtaatg
    29641 tagaaaaaaa gaaagaatta gtagtagcga cttctggcac actgtttccc gcatcttatt
    29701 ataatgatca aaatgaatta gttggttatg atgtagattt ggcaaaagag gtggctaaac
    29761 ggttaaatgt caaaatctcc tttaaagaat acaacgtgga tggacaaatc acttctgttt
    29821 caaaaagaga atcagatttt gctgcgaacg attttggtat cacaaaagaa agagaaaaaa
    29881 aattctccct ttcagagact ttcaaatatt catttgacag tatgatcgta cgaaaaaaag
    29941 atgattcagg aatccactca cttgaagatc ttaaagggaa aaaagcagct ggcgaaccca
    30001 atactagcta tatgcgttta gcggaaaaac acggagctaa attagtcaca tatgacaatg
    30061 ccacgaatga tcagtattta agcgatgtag caaatggtcg aacagatgtt attctaaatg
    30121 attattatct gcagaaaatg gccgtatctg ctttaccaga tatccctgta aaaatactgg
    30181 agaacgttta tttcaatgaa aacgaaagtg gttttttatt gaaagaagga aatgatgctc
    30241 tgaaaaagaa aatcgatggc gtattaaaag agatgaaaga agatgggacg acaaagaaaa
    30301 tatctgaaaa atattttcaa actgatgttt cagtcaaacc gaaagaaacg atggctgagt
    30361 cggtgagtga gtgatgtact ttcctctaat tgatttttcc ctcatgtgga cttcacttcc
    30421 tttcgtactg caaggcttgg tatacacatt agggattggc ttcgtgtcgt ttcttttagg
    30481 aaatctggta gggttgcttt tgacagtttt aggtcttttg gattggctgc ctctgaatgt
    30541 atttattcgt ttttatttat cgttctttag aggcattccc gcactagtcc tgctgtttct
    30601 gttatatttt gggttacctt atcaattaag tgccttaacg gcttcagtca tctgctttac
    30661 gattaccagc agtgcattta ttggtgaaat ctatcgagga tcactagcag gcgtttcttc
    30721 aggtcagtgg gacgctggtt tagcttctgg tttttctttc tttggggtat tgaaatatat
    30781 cgttttgccg caagcttttc gaatctcagt accggcactc agtaacgtag ctatggatct
    30841 agtgaaaggt acttcgttag cagcaacaat cacagtgcca gaaatatttc aaaaagcaaa
    30901 gatcataggc ggtcggacat tcgattattt ttctctctat attttagttg cactgattta
    30961 ttgggtcatt tgtatcggga tcgaaaaagt gcaacagtat ttagaaaaac gttctatgca
    31021 tcagtcaatc tgaaaaatag aaatggtgct agcgtggctg gcaccatttc tattttttgt
    31081 ttcttgtata ttctgcctag tattttaaaa ccatttcatg taaaatgtaa atcgaaaata
    31141 tgttcggagg tagaaaacat gaagaccccg ctaaccatcg aaatagaatc ctcgttatac
    31201 caatattgca tcgagcaagg cggcttggtt gtagaagaag tcacgatgcc tgatgaccaa
    31261 ggaattgtag atacgcttag ctgcttgaca aaatttgatg gaagccgaga atggcgatgc
    31321 tatgagctga aagtgacaaa agcagatttt cgctctacag ccaaactgtc atttgttgga
    31381 cattataatt attttgtttt accaagtaaa ctatatgaag aagtaaaaac tgaaatccct
    31441 acaggaatag gtgttttagt gtatcgtccg tacacggttg aagaggagat gcctgcctct
    31501 ggtacatttc tgattgcgaa aaaagcagca aagaaagagc ttgctgtacc ggaagaagct
    31561 ttgacaaacc gcttcatggc ttctttattc agggaagtaa gaaaagcaaa gcaaatggag
    31621 cgaggcgtaa aatattttcc aacagatcaa ttgtacaaag aattgaaaag acgttcagaa
    31681 aatcaagatc cattttctaa cgaacgatat tatgaacggt ttttagagga aatagctagt
    31741 caggcaatca atgagttgca agaagaagtt atcgcgcttc agcatgatta tgaatatttg
    31801 aggcaacaac agcagatccg tcggttgcct acagagccat tggagtgaaa aatatgtact
    31861 atccttattt aagaggaaaa caatttgacc tattagcatt aaaagaagca ctgtcgcgag
    31921 gattgctctc caataaaatc caaccagtga tcgaaccagt acgtgattcc gctacgctta
    31981 aaaatgtgat cgaattattt caaaaaaagc accatccaat cgctgtgatc caaaatcccc
    32041 aagtaggaca attcaaatta ttcgatcagc atgtgcacag ttggacagtc aaagaaaata
    32101 gctctgtcgt ccctgcacag atcttaacgc cagaaaatct cagtgaagta ctggattcac
    32161 ctccagcgtt tcttgttttc gatggacagc actacccaaa agatacagag gtgtggaaac
    32221 agttggcagg agttgattcg aaatttttga taccagatac tagtcgcttt cgcatctggc
    32281 tgcccgaaaa caaaattgtg atccgtgact cttttcaaac gagaaagcat gttgaaagtt
    32341 atgcagataa aacagatgac ttttttagtg atgactatct ttttttccac gcagacggat
    32401 atattggatt ttctgatttc acgatcgaag gtagccgtta tttcgataaa gggttcccta
    32461 gccgagcgct tgctatccat ctaacgtata ttgatgctta cggcaatata cgcgtgaaac
    32521 attttgtctc tgacagtaac gactctgcta aagaccaagc attgaagttt cttgaagcag
    32581 gagataaaat gaaaaaatgg atcatgcgtc accatcatca actcttgatt acttcaggaa
    32641 tgattgaatt attggctctt taccagcaac aaaaattccc tggactggga gtgttgaaaa
    32701 agtggtcact tatgcatcat ttggaactta ttagtcacct gctagatcat ccaaaagatt
    32761 ggcttaaata ttattcaaaa gttcaggaac tatatgaagt gatccaatga ttagataatg
    32821 taaatgaaaa aggaatagaa aagaggaaac tggatgtata ttcggcaaac aaggaaagaa
    32881 gaagtagaag aagtggtaga aatcattaat gccgcagcgg atttcattgc ttcgcaaggc
    32941 tctcctcaat ggcaaaacgg gcagaaacca acaaaagaaa cgattttgaa cgatattgaa
    33001 agaaaagaaa gctatgtatt aatagtggaa gatcaaattg ctggaacagc tgcattagtc
    33061 tcaagcgtgg atcccgttta cacaaaaata gatggtagtt ggaaagaatc aactggtcct
    33121 tatttatcga ttcatcgtgt cgctttagca gaaagtactc gaggaaaaaa actagcaaaa
    33181 ccgttcttag aacatttgtt gacgattgca gccagcaaaa atatccaaga tatccgtatc
    33241 gatacttatc cagctaatga accgatggaa aagaccatct attctgctgg attcacttat
    33301 caagggatga ttgaatttcc ttttgaacac ggcgaaagaa aagcatatca aataatcatc
    33361 aattgactat aaaatcatct gagcaaagat aaagacatta acactactga aaaaaacaat
    33421 catatgatag ccaagaggtt gtaacagaag tggccagctt caaaaaacaa gaaagaattt
    33481 ccgaaaatgc ttctcaaatt tttgtggaat tttagcgtat tttacgaaat agctgctttc
    33541 tgaaactccc ttcatcgaga ggtcgtgaca tagcttttgt cacgacctct cggcttatcc
    33601 tacgagtatt attcgataca tttatatcaa taatcctttt tttattttat ctgcagcttc
    33661 ttggaacgct ccatcgtttg acacgactaa aagtgagggg atagctttca aacgtttcaa
    33721 ctgtgctaaa tcttctacat aaaccgccag tctggctgaa atctgttcag atgaatctcc
    33781 acgttttttc aggcgcgatt gcaatgtttc tttagagatc gtaataaaga taggacggac
    33841 taccgtcccg aaatactcat ataaatgcca aaaaccattt gctgtcaaaa cggcgtaaca
    33901 atttcctact gtcagtttct ttttaatttc tgctttactg gaaccatatt tatgttgagc
    33961 atattggtcc cactctgcaa actcatttcc cttgatcatc tgattgaatg tattgtcaga
    34021 aacaaaataa taatcctctt gatctttttc cccaggtctt ggtgatcgat tcgtgtaagt
    34081 aatgatcttt tgttccggct gaaaaatagc ttctgcgagt gaagtttttc cagaaccaga
    34141 aggaccgata aatacatagc aataattcat tgtcatttct cctttgatga ttgaacaagt
    34201 gaaaaagctt tggaaaatat ttccaaagct tttaaaagta actttgcttt tttgtatatt
    34261 ataccagcaa gccagtcaca atagcactta aaaagctgac taaagtcgct gttagcaaaa
    34321 ttttcaatcc gtgttttgcg acaagatttc ctttttcttc atttaatccc ttcatcgcac
    34381 cagaaatgat cccgatagaa gagaagttgg caaatgaaac gaggaagaca gatataattg
    34441 ctgttgtacg ctcagtaaaa tggaaattac catttgctaa ttctgtcata gcaacaaatt
    34501 catttgtaac cagtttagtc gccatgatac taccggcatc cactgcttct ttccatggga
    34561 ttccgctgat gaaggcaaga ggggcaaaga tgtaacctag gatctcttgg aaagtgatgc
    34621 cgaatatccc gtggaagata gcattgatca tggcaatcaa agcaacaaaa ccgataagca
    34681 tagcagcaac cgtgatcgcc acatggaaac catcaagaat gtattctccc aacatttgga
    34741 aaaatgtctg ttctttgttt tcttcaatga tcagctcatc ttctttttct tctaatacat
    34801 agggatttac aattgaagcc agaatataac cgccaaataa gttcaaaaca agggcagtga
    34861 tcacatattt agaatcgatc agtgccatat aagatccgac gatcgacata gaaactgtag
    34921 acatagccga tacactcatg gtgaacaaac gtttctcaga taggaagggt aattcctttt
    34981 ttatggaaat aaaaacttcc gattgtccta aaatagcaga agctactcca ttataagatt
    35041 ccaatttgcc catcccgttg attttactta atcctagacc aacagctttc ataaataatg
    35101 gaagaatctt gatatagcgt agaataccga taatagcaga aataaataca attggcatca
    35161 atacggaaag aaagaaaggt gcacttcctt tatttgctac accggcaaaa acaaagtcaa
    35221 caccttgccc agcaaaagca agaagatgat caaacatttt tgccaataca gaaacaaccg
    35281 ctgtaccaaa agttgtacgt aataatacga aaccaagaac aagctgtaaa acgaacatca
    35341 caattagtgg tttcaatttg attgcttttt tgttactgct gatcaaaaaa gcaagcccta
    35401 atgtgacaaa taaaccaata atacctaata aataactcaa ataatcactc ctattccaaa
    35461 ttccgtttta ttttacctgt tttgcaaata aaatactaat ctttagtgaa attttcatta
    35521 cttttttaga gtgaaacgca ttcattttcc attagaaaat aaagcgaaca aaataaaagg
    35581 tttaaaaagt gtaacgtctt agtaaagtct ataaaaaaac gaaactatcg attaagctaa
    35641 tagtttcgtt ttcaacattt ataagtaaac tttttctatt ggtaatatag attttcggaa
    35701 gggtagacag gtgcgcaggt aatatcgatt cctagttttt tcaatgtttg ttcatcattt
    35761 ttattgacca tcacagtaga gtgggcttgt gctccctcaa gttcagctag tttatcataa
    35821 gcaacttgag cgattggatt cgttactgca ctgattgata aagcgatcaa gacttcattg
    35881 atgcttagtg catccaaaga ggaatgaagt gtctttgatt tcaatccttg tattgtttca
    35941 agaactaatg gtgacaataa aggaatgtca tctgcgatat gggctaaatg ttttactgca
    36001 tttaagataa ctgccgctga cgcatccatc aatgaacttg tacgcccggt aatgatgact
    36061 tcatctggta attcgattgc aatcacagca gaaggatctt ttgtaggact ttgcgcttga
    36121 atcttatctg catagtcatg ggcagggact accacgtttc ggtcttcagg acgtaaaccg
    36181 acttcttcca taatcagttt gattcgatta actgcttctt cgtcgatcaa tccttttttg
    36241 aagtcgcatt ctgtttggaa ataacgacgg atgatttctt gtttagaggc ttcttggaca
    36301 acggtatcat ccacgatccc aaatcctaca cgattcacac ccatgtcagt aggagattga
    36361 taaacagatt ctttaccagt aattttttca ataatacgtt tgattacagg aaatgtctca
    36421 acatcccgat tatagttcac agctacttta ttgtaggcat caaagtggaa ggaatcgatc
    36481 atattgacat cttttagatc gactgtggct gcttcataag caatgttcag cggatgtttc
    36541 aacggaacat tccatactgg gaaagtttcg aacttggagt aaccagctgc atgtcctttt
    36601 tggctttcat gatacagttg gttcaaggaa gtagcgagct ttccacttcc tgggccagga
    36661 gctgtcacta caacgattgg tttagttgtt tcaatatact cattttttcc aaaaccatct
    36721 tctgagacga ttttttctac gttgactgga tagtcttcga tttctgagtg tttatagacc
    36781 ttgatgtttc gtctttctag tttattgata aagactttcg tggcaggctg tccactatag
    36841 cgagtgataa cgacactgtt gattaataag ccataaccac gtaattcatc gattaaccgc
    36901 aagatatcca tatcataagt aatcccataa tcaccacgga tcttattacg ttcaatatct
    36961 ccagcataga cgcaaatcag tatttcagct tgatctttca atttttgcag caatttgatt
    37021 ttcgcatctt cttcaaatcc tggaagtaca cgtttcgcat gcttgtcgtc aactagcttc
    37081 ccaccaaatt ctaaatataa tttgtcatag tggttcactc gttccaaaat atacgctgac
    37141 tgctcttcaa tatatttttc tgaatcaaaa ccaatttttt tcactaggtt ccctccttaa
    37201 gtactaaagc attttttcat ttttttgagg attcgtcaac tggaagagcg aaattcctca
    37261 aaaaaacaaa gaaaatggtt taaaccaact tgtctagata gttattcatt ggtatgatag
    37321 tttttgataa ggaaggtgct acatgaaaaa aagacagaaa aagaaaaacg catataaaca
    37381 ctatatccgt tcgattttta ccggttatga aagaatgctt gaagatcccg aattggaaca
    37441 attgacgttt acttatctaa acgaagaaac gcagctaact cgtgatgagc atcagcgcat
    37501 tcatttcaca acaagagatc tgcctagtaa ataaaaaata agataaaggt catcggattc
    37561 gattctgtcc tatcagatgg aaagactagt tgatcgaaaa aaaggctgta ccaaattttg
    37621 gtgcagcctg ttttatggag cattgcccgc tcttttttat aacaattttt tacagaaaat
    37681 ggtactattg aagtattaat aagtgaaaaa cagatgagta agaggaggca agtagtatga
    37741 aagagccaga tacaaatgca aattatgagc cagacgaact agaggagacg aatgcggatc
    37801 aggatacagg acaagaatcg tcttcttttt acgatatcaa agaaaaagca agcatgaatc
    37861 tttcccaatt attagaagac ttacaggctt ttgaaaaagc tgtccgcgaa gaagatatcc
    37921 ctgagatcta ccgtttatac aatggccgat tgaatgaaga attaaaaaga agctcaaatg
    37981 aaaatcacga gatcgatcaa ttgctgatgc gtaagatcca tgatcgtttt ttacaggaat
    38041 ttccttttat ggaacaagta gaaaacatct cgccaacgat gagctattac aaaatcggca
    38101 cttattacca tgatcggccc acggtcggta ttgatgcaag tctgccagaa atttttgttt
    38161 tgcctaagat cgatgaagag tgggagaaat attcccaacc ggagtcaacg gactatgaca
    38221 aaaaaatcaa tgagctagac gcaaaggtga tcactgctca gacagaaatt gaacgtttag
    38281 atgaacaaat aaaagaaatc aatcgacaaa tgactgattt gaacgacaat aaaggattct
    38341 tgaatcgtaa aaaaatcgag gaagaaattc aagaattaga gaagaagaag caagtactat
    38401 ctaatgaaaa attaggctgg cttccttata ttgagacgcc tgaaacaatc cagcagcaaa
    38461 aagaagcatt gaagcaagaa gcaagagcag accagcttcg tgcagccatc gtagaaaaag
    38521 aacaaaggca aatcagacgc tatttcggta gcaaagaggg attcggtcaa gcaatccatg
    38581 aattcttgat gaattatctt ggcaatgaga atcctaataa tcaatctaat gaaggaggtt
    38641 ccgagtatga atgaacacga tgaagcagaa tggacaaaaa atgaagaaca aacagaagat
    38701 catgaagaaa cgaacacttc attggaagaa caaacaagta atcctctgga tgacacagaa
    38761 gaaatcccta tgctagagga aacaaaaata cacgaaaaag aaaaagtaac tccgacgaat
    38821 acgaatactg cagaaaacac ccatgcttac gaaataactg aaaatcccgg gtatttagaa
    38881 ggaaaagagc aagatcatca agatatcgtc agtttgattg aaacagcgga agcagaatta
    38941 gcggatttac gtatgagaaa agatttgatc gaatcagatt ttccacaatt attagaatca
    39001 tatgatcgtt ttatattgaa tgaagaacca atctccacga tcggaaagac aagcctgatc
    39061 gaatacttca cgtatgaatt actgaaaccg ttgaatgata ttggtctgga acggtcaaat
    39121 tcagcttatg acacatggaa aacaagacat ttttcgatca attatacgtt gaatggacaa
    39181 aacgaattag tcttttcctt tgtattaccg accatcgatc aacgatacca agtggaatcg
    39241 atgagtctcc taaacgtatc accagagaca atggaaatca atgtccaaga tgaccgggtg
    39301 ctttctttga tccgacactg gtcagtggat cgagtattct ctgcagggca gatcacgata
    39361 ttcaatcaca aattgaatca attattagcc catgcaagaa cacttggttt taccgttaat
    39421 cagacattac tagacaatac gaagccactt cgtttgaatc ttcagagcga atttgaattg
    39481 acgaatgaag tattggatga tatttttatc gtggcaatga aaaatccatc ctacgatatg
    39541 gaaaagatca acgaaactac ttatcaagta cgattagata aaggacagtc tttaacgata
    39601 acaacaaacg aaaaagatca aacagtcttg tcgatctcat ctggagacta cccacgatct
    39661 gtcattgatt tctttatcaa ttacgaattc ttggtcccat taatggtgag aaagtcctga
    39721 ttggataagt tggattacca gatgtcattc agataattct gttccaaagg acttgcggca
    39781 gttatccaga ataattgtca caagtctttt ctgtatgtac taaatggacg tgaataactt
    39841 gctgatgaag gagggatttc attaggaatg tccacaaata aaatagcaca gcttagctta
    39901 ttgtctgctg cttgtgtagc aggtaggatc gcttttcaat ttattccgaa tttccagcca
    39961 atgactgcta tttttttatt tatagtactt tacttaagct taaaagatgc gttaattgtc
    40021 atgagtcttt ctattgcgat cagcagtttt tattttggtg ttggaccatg ggtcatcggc
    40081 caatggatca gctatactgt tgttctgagt ttgttttcaa tcgtctgctt gagaaaaaca
    40141 gtgcaaagga atctatggtt aaagggagtc tgtttttttc tggcgggcat ggtttacgga
    40201 ataggtatga ccgtttttga tacgctgtta tatcgtttgc ctcaaccttg gatctattac
    40261 cttcaagggg tgtcgtttga tttgatgcac agtataggca atgttgtgtt ctttcttgtt
    40321 tttctgccag tcgtcaaacg tttttacaat cattcaggag gaaaaaatga aaaaaataat
    40381 ttatagtttg cttgcaatga gtgtcagtat actcattttg acaagttgca gtacaaccta
    40441 tacacaatcg gcttccaacc aaaaggagga agtaaaaaca tcgcaaaaag caacaatcac
    40501 gttacaagaa aatggtcaaa acttttcgga aaaagaagtg gtcttcaaaa aaggcgatga
    40561 tttactgagt attttgaaac gaaattttga agtcaaagaa gataacggct tcatcacttc
    40621 gcttgaaggg cactcacagg atgagaaaaa tcaactctat tggatgttta ctgtggacgg
    40681 gaaaagtgct actactggtg ccaaagagat caaattgaat gatggacaat cggtcatttt
    40741 caatttgtct aaactataag tttcataaaa aactgttaaa gggcgaatat tgccataatt
    40801 cagtgagttc agttgatgaa agaaggaaaa taacatggaa aattttaaaa aaagcggaat
    40861 gttttccgta attgctgctc taggggctaa tattctagtt gctatcagca aatttgtcgg
    40921 ctatgcaatc agtggcagtg ccgccatgct aaacgaaagc atccacagta tcgttgattg
    40981 cagcaatcag attttgctgt tattcggtga taaacaagcc aataaaggac agagcgagtt
    41041 gcatcaattt ggtgaaggac gagcaaaata ctttttcagt acaatcgtcg caatgatgct
    41101 tttcttcggc ggtggggcac ttggggtgat ggaagctttt gaaaagttga cgcatccatc
    41161 ccatgaagtg ggtaatccga tcattgttat agcaatactg ttatttggtt tggtaatcga
    41221 aggaagttcg ttacgcgtgg caatgaaaga aatcaaagaa ttgaatactg aaaaactttc
    41281 cacgatgcgc tttttgcgcg aaagtcgaca cagtgaaata ctgattattt ttacggaaga
    41341 cttgtgtgct gtaatcggtt tggtcttggc tttagcagga acaatattga cttatgcaac
    41401 cgggattgct gcatttgatg cgatcagcgg attgctgatc ggtttcttgc tgatgggagc
    41461 cgccattttc ctagcaaaag aattttatag tctgatcatc ggtgaaagcg tgacagcaag
    41521 cgatttatca aaaatcaagt tagcttttga acgtcctgag atcagtcggc tgatcgatat
    41581 aaaaacagtt catttaagtc caacggagat tttagttgca gcaaaagcag atatcgttgg
    41641 taacaaagag aatgaagctt actcggtcat caatgatatt gaaaaaaata tgcgtcagtc
    41701 tcttcctgac aagaagatgt atatatacat tgaaacagat aaatatgacc caaattattc
    41761 tcgtaaataa aacgtttatt catgaattga agcaaaaatg agaaaaatat aatcttgttt
    41821 ttaaataaaa cggctacaat ttagcgaatt tatgttacaa tgagtccgct gtttatttgt
    41881 tgtaattaaa ggagatattt taatgaacaa aaagaaaagt gcgccatggc ttcaagcttt
    41941 gcatgcagtg atgccacttt gtataagcta tataccagta ggattagctt gcggagtatt
    42001 gttgcaaaaa gttggatttg atcctctctt atcaggactg ttatcgattc tggtcttttc
    42061 cggtggcgcg cagtttttag ttgcatctat gcttacgacg caagcatcat ttgcaacgac
    42121 attattgatg gttttctttt tagaattacg ctatacatta ttaggagcaa gtcttgccgg
    42181 ttttatgaaa aaagaaaagc ggacgttttt ggctgtcttt tctcaatcac tgaatgatga
    42241 aaactatgcg gtgaactact taaagttttc aactgaccct tcctggaata aaagaaaggc
    42301 tttatatgtc aattggttct caatgactgc atgggccggt agcaatatga tcggtaattt
    42361 tttcggctcg gtgattcgag tagatgctga ccttgtccat tttgctttga cggccatgtt
    42421 cattttcatg tttatcatgc agatgaaaag cgcactactg atctttacag gtttattctc
    42481 aggcgtatta ggggtcgtat tcatggtatt attccaaaat actttcggat tgattgcagc
    42541 aacagtcatt gcttcatttg ccggatttat gctggagaag gcattcaaaa aagaaaaagc
    42601 taagaaacta agagaccgcg gtaaagatgt caatgagccg ctcttcaact tcccggaaca
    42661 ggaggccaat caccatgact aaactatatt tgctactttt agttgcttgt ctgttcatcg
    42721 tggcatatat cccgcgcttg ttcccgatgc tttattttac tcatcgaaaa gtgccatcct
    42781 ggttcagtga ctggatgaaa tatgtaccgg tggcattatt tgcggcgtta gcttttaaag
    42841 atgttttcat tactcatgaa catctggata ttgcttggaa tatcaaaata gctgcaatga
    42901 ttctagtagc aggcgtggct tacaaaacac gttcgatggc gttgtcagtt ttgacaggac
    42961 ttgcgtctgt ctttttgctg tctatgcttt aaactgtttt attttattaa aaacagagat
    43021 tgcgacataa gttgttcaaa ctgatctatc cgaactgcat ttgcaacagt caattctgga
    43081 tgcaagttta ttcgtaggga taaaaaagat tagtgttggc ttatgatgca agctcttttt
    43141 tattttagga attagagagg gatttgtcct tctatgattt tttgctataa tagggaagat
    43201 gtttatttta tgaaagaata gttgagggaa tttaaatgaa taaaaaattg atgcaaggaa
    43261 cattttggct aacctttgct aatcttctat gtaaagtttt aggggtagtc tatttgattc
    43321 cctggctaag tatgatgggg aacaatcaag atggtatgct tgctacgaca ttgtataatg
    43381 ttggctatct tccttatgga ttgttcctga tgcttggtac agtcggattt ccaaatgcga
    43441 ttgcaaaaaa agtagctgta gccacaaaag aaggagataa cgctgcttgt cggctgattt
    43501 ttagaagtac gatcaatatc atgtttgtca tcggtatcgc ctctgctgca ctgatgtatt
    43561 tatttgctcc tttactagcc ggaatcagtc cgattgctaa cgttaataat gggatactag
    43621 ctatcagaag tttatgccca tctttgattg ctatcccaat tcttagtgca atgagaggat
    43681 atttccaagg aaaaaatgat ctgcggcctt atggaacttc tttgattatc gaacaggctg
    43741 tgcgagtgat cgttatcttg gctggtactt attacttgcg cgtattgact gacggaacca
    43801 tattagaagc tgtattgatc agtacagtcg cttctttctt cggtgggtta gctgcgatta
    43861 tccatatgta tatcgtcgga cgcagaaaag acttcttcga acttaaagat tttttgattt
    43921 ccagccgtta tttcgaaaga gaaaaccgat ctgcctctgt ctctatcatt cgggaaacac
    43981 taccgtttat ttttgtcggc tcagtcatta ctatcgttca aatgatcgac caagtaacga
    44041 tgaaaccact gcttcacttt ttccgtccag agatcgcaga tcagcaactg gaattcttat
    44101 tcagccgtgc ttctgtcaat ccaaataaat tgacattgat cctgatctcc atggtaggaa
    44161 cagtagctat aagcagcttg ccaatattaa gcacgatgaa gaaaaaagat cggatacaaa
    44221 tcgaaaaaac agtaggagat agtttttcga ttgcgttatt gattcttctt ccttcattga
    44281 ctggaatgtc tttattagct ggaccactat acacattgtt ttttggctat gatcctgaaa
    44341 gtgtcggata tttccaaatg gctttgctag cttctttgtt tttctcttta ttcacgatcc
    44401 tatctacgat gcttcaatct ttgaatcacc atcgttttgc gatccgatta actgtagaag
    44461 caattatcct gaaagtcatc ttccaagtaa tcggattagg attagttggc ggatacggga
    44521 tgagcttatc aaatggctta gcattcggta ttgtctttgt tcgcggctat cactttatgt
    44581 gcaaagaata ccgaatagca cctttagcaa agatcagcaa ttttttctta aaaactttcc
    44641 gctccaccct gattatgctt gcagtatgtt ttgccgtttt ctttttgctg aatcagcgat
    44701 tgtcaatgga atcaaaaagc tatgcaatga tttattgtgt ggctgtagga agtattggcg
    44761 gcttagtatt tttattttct caattcggaa aaaatgggtt tcgaatgttg aaaaatgtta
    44821 aacatcatag cagaagcaaa gaataggtta actaatcgtt ttttgctgtc acttgaaaaa
    44881 cggcaactcg tatgattacg cttgtcgttt ttctattttc caattttagt ttcatatcta
    44941 atcttactta tgatatagtt ataaggtctg gaaaaattct ttgaaacgag gaaattaaac
    45001 acatgaaact tgcagtagtt acagatagtt cggcatatct gccggaacgt atcaagaacc
    45061 atcccgactt attcgttatt ccaatccctt tgattatgga tgggaaaatt tataacgaag
    45121 gaatcgatat cgaagcggat gaatattatg gacttttaaa aaacagtaaa gattttccta
    45181 ctacttcaca acctgtcgta ggggaagttt tgggtttata tgaggaattg aaagagaaag
    45241 ggtatgacac gattttaagt atccatcttt cttcagggat ttctggcttt gtcaacacat
    45301 tatttgcgat gaaagatgac atcagcggag taacggtcat tccttatgac tctaagatca
    45361 ctagtatgcc gatgggacac atggtagaag ctgccttaga cttaaatgat gaaggtcagt
    45421 cccttgatga aatacttgca catatcgatc gaatccgaga taatacctat gcttatctga
    45481 ttgtagatga tttgaacaat ttagtacgag gaggacgttt gacaaatggt gcagcgctga
    45541 ttggcagctt attaaaaatc aaaccgatcc tgacattttc tgaagggaaa attgttttat
    45601 tcgaaaaaat ccgttcaagt aaaaaagcat ttgctcgagc tgaagaaatt attggtagaa
    45661 gaaataacga aatacaaccg ccagtcaaac tttacgtgat acatgcaaat aatttagaag
    45721 tagcgattgc ggagaaagag aaattgcaga aaaaatatcc aaatgcagaa atcgaaattg
    45781 gtcatttcgg accagtcatt ggtacacatt taggtgaaaa agccatcggc attgccattt
    45841 cagcgcaata attcctttta ttcaaaaaac ataccaaaaa tat
//
LOCUS       DAFENC010000021        43678 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.021, whole genome shotgun sequence.
ACCESSION   DAFENC010000021
VERSION     DAFENC010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 43678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43678
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.021"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(105..629)
                     /locus_tag="LP493_001469"
     CDS             complement(105..629)
                     /locus_tag="LP493_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2133627.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="LP493_001470"
     CDS             complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="LP493_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HBL2133628.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(1218..2198)
                     /gene="pta"
                     /locus_tag="LP493_001471"
     CDS             complement(1218..2198)
                     /gene="pta"
                     /locus_tag="LP493_001471"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HBL2133629.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(2351..3031)
                     /locus_tag="LP493_001472"
     CDS             complement(2351..3031)
                     /locus_tag="LP493_001472"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBL2133630.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            3157..4026
                     /locus_tag="LP493_001473"
     CDS             3157..4026
                     /locus_tag="LP493_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL2133631.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            4052..4567
                     /locus_tag="LP493_001474"
     CDS             4052..4567
                     /locus_tag="LP493_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133632.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(4614..5207)
                     /locus_tag="LP493_001475"
     CDS             complement(4614..5207)
                     /locus_tag="LP493_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2133633.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(5232..5411)
                     /locus_tag="LP493_001476"
     CDS             complement(5232..5411)
                     /locus_tag="LP493_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133634.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(5488..5997)
                     /locus_tag="LP493_001477"
     CDS             complement(5488..5997)
                     /locus_tag="LP493_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133635.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(6093..6472)
                     /locus_tag="LP493_001478"
                     /pseudo
     CDS             complement(6093..6472)
                     /locus_tag="LP493_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644319.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            6802..7551
                     /locus_tag="LP493_001479"
     CDS             6802..7551
                     /locus_tag="LP493_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HBL2133636.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(7735..9012)
                     /locus_tag="LP493_001480"
     CDS             complement(7735..9012)
                     /locus_tag="LP493_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133637.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(9091..9735)
                     /gene="pcp"
                     /locus_tag="LP493_001481"
     CDS             complement(9091..9735)
                     /gene="pcp"
                     /locus_tag="LP493_001481"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBL2133638.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(9934..10878)
                     /locus_tag="LP493_001482"
     CDS             complement(9934..10878)
                     /locus_tag="LP493_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBL2133639.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(10880..11566)
                     /locus_tag="LP493_001483"
     CDS             complement(10880..11566)
                     /locus_tag="LP493_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBL2133640.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            12040..12360
                     /locus_tag="LP493_001484"
     CDS             12040..12360
                     /locus_tag="LP493_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HBL2133641.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            12514..13419
                     /locus_tag="LP493_001485"
     CDS             12514..13419
                     /locus_tag="LP493_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2133642.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            13416..14189
                     /locus_tag="LP493_001486"
     CDS             13416..14189
                     /locus_tag="LP493_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBL2133643.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(14370..15794)
                     /locus_tag="LP493_001487"
     CDS             complement(14370..15794)
                     /locus_tag="LP493_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2133644.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            16005..16451
                     /gene="nrdI"
                     /locus_tag="LP493_001488"
     CDS             16005..16451
                     /gene="nrdI"
                     /locus_tag="LP493_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBL2133645.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(16516..18498)
                     /locus_tag="LP493_001489"
     CDS             complement(16516..18498)
                     /locus_tag="LP493_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL2133646.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(18512..19408)
                     /gene="murQ"
                     /locus_tag="LP493_001490"
     CDS             complement(18512..19408)
                     /gene="murQ"
                     /locus_tag="LP493_001490"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBL2133647.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(19411..20472)
                     /locus_tag="LP493_001491"
     CDS             complement(19411..20472)
                     /locus_tag="LP493_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBL2133648.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(20683..21249)
                     /locus_tag="LP493_001492"
     CDS             complement(20683..21249)
                     /locus_tag="LP493_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBL2133649.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            complement(21277..22779)
                     /gene="eat(A)"
                     /locus_tag="LP493_001493"
     CDS             complement(21277..22779)
                     /gene="eat(A)"
                     /locus_tag="LP493_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBL2133650.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(23037..24158)
                     /locus_tag="LP493_001494"
     CDS             complement(23037..24158)
                     /locus_tag="LP493_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBL2133651.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            24284..25225
                     /locus_tag="LP493_001495"
     CDS             24284..25225
                     /locus_tag="LP493_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBL2133652.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(25375..26271)
                     /locus_tag="LP493_001496"
     CDS             complement(25375..26271)
                     /locus_tag="LP493_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBL2133653.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            26540..27880
                     /locus_tag="LP493_001497"
     CDS             26540..27880
                     /locus_tag="LP493_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2133654.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            28098..28541
                     /locus_tag="LP493_001498"
     CDS             28098..28541
                     /locus_tag="LP493_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HBL2133655.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(29045..30463)
                     /gene="nhaC"
                     /locus_tag="LP493_001499"
     CDS             complement(29045..30463)
                     /gene="nhaC"
                     /locus_tag="LP493_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBL2133656.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(30866..32089)
                     /locus_tag="LP493_001500"
     CDS             complement(30866..32089)
                     /locus_tag="LP493_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBL2133657.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(32120..32959)
                     /locus_tag="LP493_001501"
     CDS             complement(32120..32959)
                     /locus_tag="LP493_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBL2133658.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(32976..33656)
                     /locus_tag="LP493_001502"
     CDS             complement(32976..33656)
                     /locus_tag="LP493_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2133659.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(33658..34731)
                     /locus_tag="LP493_001503"
     CDS             complement(33658..34731)
                     /locus_tag="LP493_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2133660.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(34787..35025)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(35068..35301)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(35378..36049)
                     /locus_tag="LP493_001504"
     CDS             complement(35378..36049)
                     /locus_tag="LP493_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBL2133661.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(36136..38814)
                     /gene="mgtA"
                     /locus_tag="LP493_001505"
     CDS             complement(36136..38814)
                     /gene="mgtA"
                     /locus_tag="LP493_001505"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBL2133662.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            39473..39910
                     /gene="ndk"
                     /locus_tag="LP493_001506"
     CDS             39473..39910
                     /gene="ndk"
                     /locus_tag="LP493_001506"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HBL2133663.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(39932..40798)
                     /locus_tag="LP493_001507"
     CDS             complement(39932..40798)
                     /locus_tag="LP493_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL2133664.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLSHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(40958..43051)
                     /locus_tag="LP493_001508"
     CDS             complement(40958..43051)
                     /locus_tag="LP493_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBL2133665.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
BASE COUNT        12613 a         9150 c         7717 g        14198 t
ORIGIN      
        1 tattcaaaaa aaatggactg cgacacgact tttgtcacag tcccttcgtg tgtttttctg
       61 ccttctcaaa aggatgacag tttctcactc ttttcctatt tcttctattc aatcaaataa
      121 ctcattttat atacatctaa aaattcacct agatctgttc ttgcccctct aggcatgacc
      181 gcttcgattt ggaagcccat ttttcggtaa aggtgtacgg ctctttcatt acgaacttga
      241 acgtcaagct ccaatcgaaa aagtacaccc atttccttcg cccaactgat gatttcttct
      301 agcataagag tgcctagtcc cattccccaa tattcctgca gaatactgat accgacttct
      361 cccacgtgag acaaacgaaa ttgactgtct gccttgacag atgctgttcc aataatcgtc
      421 ccttcataga ttgcaagcag caataaatta ttattgcttt cgtatatata atccaactct
      481 tcttctaagg tttctggtgg taacaggagt tctgcttcat ccaaaactaa aaattctgtc
      541 tccttattaa cttgtcccat catcaaaaga atgtcttttg catctcctgg cactgcttcc
      601 cgcaagatga tcccaacttc ttcactcatg attttcagcc catttttcta gaattcgctg
      661 tttgaaggtt tcactttgct ccccgtatga gattagtttc acataccgct tttctaaatc
      721 tgtatcactt ttttctaaaa tcagttccaa ataatcctcc ggcagtgctt cttctaatag
      781 atttccccat tcaacaacgg aaagcccatc accttcaaaa tattcatcta accctaaatc
      841 tgctccgcta gctgctaccc gataaatatc catatgatac aacggaatcc gaccttgact
      901 atattctcta ataatcgtgt atgtcggact tttgatcatt tgcgttatcc ctaatccttg
      961 ggcaattcct ttcgtcaacg ttgttttacc cgcacctaga tcaccagtca atatcagatt
     1021 gtcacctggc attgcggaat gaccaattgc ctctgcgaat tgttctgtca ttgttaatcc
     1081 tgatagttcg atcatttttc atcttctccc gctcttcttt ctttttgcca gtatatcgcg
     1141 taatgaagtt tttttaaaga aaaaatgaac tagtcaagaa cagcagctgc tgtttttggc
     1201 tagttcgcgt gtatttgtta atcaatcaat gtttgtgctg ctgtgataat cgataattta
     1261 tatacatctt cttcatttgc tccacgagac aaatcagaaa ccggtttgtt caagccttgt
     1321 agaattggtc cgattgcttc aaagttaccg aaacgctgag caattttata gccgatattt
     1381 cctgactgca attctggaaa tacaaagact gttgcttgac cagctacttc tgaatctggc
     1441 gctttcagtt gtgcaactga aggaacataa gaagcatcaa attgcaattc gccgtcgatc
     1501 atgtattgtg gcgctagttt tttagcgatt ttagttgctt caactacttt gtctacttct
     1561 ggcgatttcg ctgagccttt tgtcgagaag ctcatcattg ctacttttgg ttcgatatcg
     1621 aacaattctg ctgtttttgc agaatctacg gcgatttcag ccaattcttg cgcagttgga
     1681 ttcacgttga tcgcacaatc cgaaaagaca tatttttctt gatctcttcc acgtaccatg
     1741 atcatcgctc cgcttgtccg actgatgcca ggctttgttt tgatgatctg aagtgctggg
     1801 cgaacagtgt cgccagtcga atggatcgct ccagagacca ttccgtctgc aatccccata
     1861 tacgtaagca tcgtaccaaa gtaattcaca tcttttaaaa tcttttctgc ttgttctttg
     1921 gatgcctttc catttctacg ttcaacaaaa gtatccacca tttcatccca cttatcgtaa
     1981 ttatcagggc tgatgatcgt aaagctagat gttttgattc ctctggcatg cgctgcattt
     2041 cttatttctt cttcgttccc tactaaaatg ggttccacaa gttcttctgc tttcaaccgg
     2101 gcagctgcgc ctaaaatacg agcatcagta gcttccggga aaacgatttt gatcccacgg
     2161 cgaacaattt taaatcttaa actatcaaac aattccacaa gatgacctcc agacgttttt
     2221 atatgtatta tcatacacta ttccagaaaa aaagaacagt ttattttatc tgtatcagtc
     2281 aaaaatgctg gaaaaattaa gtttttcaca tacaaagcga actgcactat aacaggaaag
     2341 cgctgtttta ttacactgtt tcaggcagtt gccaatcaat cggttcttct cctaacgcaa
     2401 ggagcgcatc attcgttttc gagaagggtt tggaaccaaa aaagccacga cttgcagata
     2461 acggactggg atgtggagat gttatgatga tatggcgact cttatcgatc attttgattt
     2521 tttcttgtgc cggttttccc cacaagataa acacgattgg tttttcccgt tcatttaatt
     2581 tttcaatgat cgtgtctgtt aatctttccc aacctttccc gcgatgagaa tacgcttgcc
     2641 cttcccgaac ggtaagaacg gtgttgagta aaaggactcc ctgtttagcc catgacacta
     2701 gatttccatg ttgaacaggt gcgattccaa gatcatcata aagctcttta tagatatttc
     2761 ttaacgatgg cgggatcttt acgccaggtt gcacagaaaa agataagcca tgagcttgat
     2821 tttctccatg ataaggatct tgtcctaaaa tcaccacttt aacttcttca taaggagtca
     2881 attccaatgc ttcatagata tgatacatat ctggatggat cttttgggac gcatattctt
     2941 tttttaaaaa ttctcttaga tgcagataat aatcttttga aaattctgag gacaaaactt
     3001 cttgccaact gttatgaatg atttctttca aaaactccac ctcctaataa aaagaataac
     3061 tcacattttc ttcaatcaca agggacaatc ttcaccctca gcacttgatt aatatggtaa
     3121 actaggaaca agaagcagaa aggaacgata atcattatga tcaaattaat tgcatcagat
     3181 atggacggca cattattaga tgcccatatg agtgtttctc ctgaaaatgc cgaggcgata
     3241 cgttttgcaa atgatgccgg tgttgagttc atggtcgcta ctggtcgaaa ctatcaagaa
     3301 gctcgcgcag ctttagatga ggtaggaatc gattgtgcga tgatcacttt gaacggggca
     3361 caggtatttg ataaagaagg aaattcattg tttaccgtgt cgattccaaa taatcaagca
     3421 atctctgttt tagatattct agatgctaac ggtatttact atgaagtagc aaccaacgat
     3481 ggtctttatt ctgaaaatca agcgaaacga attgaaagtt ttgcttccat ggtggctacc
     3541 catttacctc accttacgta taaaatggcg attgccatgg cctcagctaa gctggagtta
     3601 ttgcacatca catacgtgga cagtattcgt gctattttgg aagaaaagaa tctggaagtt
     3661 ttaaaaatta tttgttttca tacagaaggg ccagctgtat taggtccagt tggaaagcag
     3721 atttctcttt taggcgatct agccgttact tcctctggtc aaaacaatat cgaagtgaac
     3781 cataaaaacg ctcaaaaagg aattgctgtt gcccatgtcg ctcacgagcg tgggatttct
     3841 ttagaagaag tcatgacgat tggcgataac ttcaatgatg tcagcatgct gcaagtagca
     3901 ggagtcagtt tcgcaatggg aaatgcagaa atcgaagtaa aagattatgc caaatataca
     3961 acggacacaa accttgaatc tggcgtagga aaagccatat tgcgcgcgat tgcagaagac
     4021 ttgtagtttt atctagaaaa gagggatata gatgtcagaa tttttcattc aggaaaagca
     4081 gcttggacgt gcaactcgga caattgtcaa aaacgaaaaa ggacattccc tgtttttgat
     4141 ggttggtcgc tggggaacaa agggcgatgc attgtctctt tatgccatga atggcgatct
     4201 cgttgctcac atcaagcaga taagcctgac attcggtacg cgttttgagc tgtataaaga
     4261 gttcgaaaag gtgggaacca tgcagaaaat attcaattgg cccggtgact tttattatat
     4321 tcgtagactt cactggacag tccaaggtga tatctataat catcaatatc aaatccatca
     4381 tttcaatcag caaatcatga aaatggataa agcaacactt ttttcaggag attactatgt
     4441 attggatgtc tcaaatgatg aagatgctcc agtttgtatt tgtattgctg cggttttaga
     4501 ttactggctc taccgtaaag acaaaagtcg cgataagcct gtttcttacc gacttaactt
     4561 aagttaaaaa gatgtacctg aaatgcggaa atacgcattt caggtacatc tttttagata
     4621 ttcttttgca tatgatcata aagatgacca ctgatcatcc gctgaccgac aactttgaag
     4681 tcatggcgtt cgtataattt tttagccttt ggattttttt catccacact tagaccgatg
     4741 acggagcgat tagctttctt cgccaattta ggtaatgctt ctaataatcg cgaaccgatg
     4801 ccttgtcctc taaaatcttc tgatacactg atagagtcca aataccattc gttgggaaac
     4861 gtttctttat caatgaacaa acgtgtagac gcatctagct gatatttctc taagataggt
     4921 accagtggct gatcgatgat tgattcttct tcatctgtat aaccgtaagc aactcctgca
     4981 actttaccgt ctatttcttc tacgatacct cgtgaataac tgtaacgata atttggatca
     5041 gtgattgctt cttctaaaat ctctaaagtc ttttgttccc ctgtctgctt caaaaatggc
     5101 agttccatat cttttagaat cactaagatc aatggggcga tttctggagc atcttctttt
     5161 ctcgcaaaac gaatcatagt ttcctctcct tttctccatt ctaacatgca gaaaaagaaa
     5221 tcgcaaaatc gttattttaa aaaatcttca atcttttcag taatgaaata accatgagta
     5281 acgattcttg ccgcttcagt tcggcaataa gggcagacga ctggcatttc tttatcatta
     5341 tgttcgacta cattattgac ttcttcgtat gcaaattttt ttccgcaatt agggcatttc
     5401 attttttcca tgttatctca acttcctttc atctttactc tcttagctta ctcttatatt
     5461 gtaaaaaaga gaagcaatat ccttcttcta tgcagatatc catacctgac ggtcctgttc
     5521 tccatctatt aatcggactt tataataagg acgttcatct ttgactagaa gtgtccactc
     5581 tttcactttt gcttttttcc cgtagtagct gactgcttcc ttcatcgctg cttgcggttg
     5641 tttgaactct tccgtttttt ctatatcaaa aagatgttct gcggcctttt ccgtgtcatt
     5701 tcgtacggtt gttttcccag tggatggatt gactgctatg acttgtcctt cacaaaaaaa
     5761 ctggtattca tatgttgcat tcgtaggatt ctccaaatct ttttcaactg caaaatgaat
     5821 agcagatatg ttatgttctt ttgtttcgtt ttttacgatt gctgctgctt ttttcaatga
     5881 gatccgatat tcctggtcac taatatcatc catgtgaaaa gcggcattga gcagtcccgt
     5941 cataccggta atccctatta cgatgagggc agcaacacca aacatcattt ttttcattct
     6001 tcattctcct gtttcttttt tttaaagaat atcaagaaat gaacgaatga aaaatcgaat
     6061 gaaacgaaaa aaaagtgaca attttgttat ctttattcgt gcagttctaa tggcaatccg
     6121 tctggatcaa agaaaaacgt catttttttc ctgtaaaggt atcttctcta atcggttctg
     6181 attcgatccc taaggactgc aattctgcaa ttgtttcttc aatatcgtct actttgaaag
     6241 caagatgacg caagccacaa gcttctggat agtttggtcg ttgtggcgca ttagcaattc
     6301 caaaaatctc caattcagca cttcctagtt tcagatctaa tttatagtca tctcgttctt
     6361 tgcggtaatt ttctctgatt acttcaaatc ctaatttatt aacataaaaa tcacgtgatt
     6421 tctgataatc tgaaacaatg atggctatat gatggatcgt tgtaaggttc atatgagcac
     6481 tcctattctt cgtttaagct cggatctata ttaatctcca gttccattgt aaatgtgtca
     6541 gattgaaaaa aatagctgtt tttccttttt ataagaaaaa aggcaaaaaa aacagaaagt
     6601 aggtcctcca agacactctt cctgttccca atataataaa tgaaagtaag aaattatatt
     6661 ttcaagaaaa caaacagaaa attatcataa cacaaattat ttataattga aagactagtt
     6721 ttttttcaag aaaagcatac aatagattgt gttagtaaat acagaacaca ctacatttag
     6781 tgtcttaagg agtcctcata catgaagtca tattttcagt ttttagctca tcagctaaaa
     6841 ggctggccgc aacaaaatta ttatcttttc tttttcagtc ttggctgcca ggtcatgact
     6901 cttgtcaata gtcccatcac ttggctgtcc gttattacat ttatcggtac cacgcttggt
     6961 gtattgtgta ttttatccat caatgcggca aaatcagtca acggtatttt aggtattttg
     7021 tctgcgattt gttttattat cgttgggttt tcagcaaaga actatttaag tatcggtgaa
     7081 cagattgctt atatgatcac attggatatc cccgtattgt taagtaaaga atggaatcat
     7141 aatatggctt caaaaatccg aaaattcact ggaaaaagct ggtttatcgc aatcatcagt
     7201 actttccttg tctatcttgt ttcaggattc ctgattggtc gttatacaga tgatcctcgg
     7261 ccgtgggtag atgccattgc tttttctatt agcttgactg ctggtatcat cagtttcttg
     7321 cgttacaaca accaatatta ctggtggtta gcttcagggc ttgctcaaat ggtcctttgg
     7381 tatatttcat ttacgcatgg atctgcaagt ttggcgatgt tcgtgaacag ctctgtttac
     7441 ttgctgaatg atgtccttgc atttaccgtt tcaccttggt ataaccaaaa agaacgtgaa
     7501 cgtatgcaaa aaatggaaga agaatactac aacgcacaac aacacgcata aaaaaactga
     7561 gcgtgggaca aaagtaaaga acacttttgt ctcacgctct aaacacgtat aaacggcgga
     7621 atcagaagca actccttcgg aaataagctg aaattcacaa aaatttgaaa agcaattttc
     7681 gtgaatttct tcttatttct tggagttaaa cgcttctgtc ccagcctcta ttttttatag
     7741 taattccttc agatactttc ttgcctcatc attgaaacgc agtgattctt ctaacttctg
     7801 ataatattcc aacgcttgtt tctgagcttc agtaaaacga taatgttttc ctttccattt
     7861 gtcgattgtc tcttgcacat ttccagattg gatatctttc actactagtt gccatttttc
     7921 ttttgagact gtacggtctt tcttatcagc agattgtata gcttctcgtt ctttacgcaa
     7981 tacttttaaa aaaccatttc tgactatccg aggaatgctg tcgaagaacc cttctgtaaa
     8041 accatagcga caatattgct tccaaataaa tagatagatt tttggttgga tgaatcgttg
     8101 gtttttcgca aaatattcca tctgagcagt gacttctggt gttcgttgac gttttgtctt
     8161 tctcaacacg gaaataaatg tttcaaaata agcattagga tgtactggca cttcttcata
     8221 tacgatggat tgccaatctt tacgtaaaaa tgcgcgatag ttgatcaaga attcttctac
     8281 atcctttact aattcttctg caaagtcgtc aaatagttct ttttttatct gtcgcttttt
     8341 tgactgccca ttgatgtgtt cacttatttt cttgatttca ttttccaatg cttgataatc
     8401 cgctatgtaa atcggcattt ctacttggcg aaattctgcg agccgctgag ctaattttat
     8461 atccggtaaa tatggctgtt tcatccgacg attttggtac aagacaaaac agtatttttg
     8521 ccatagtcct tcaggaaaat cgatattctt ctgcttaagc cataataatt cgtctaaggc
     8581 cagatcaact tttgtcattc cctgatggat cgaagctgcc actgtcggag agacatgcag
     8641 gtgatcggca aagtggttga tgcctagttt taggatcttt ccggtttttg gcgatttaac
     8701 gatgtattgc acttttaatt ctctaccaca ctcacaatac aatttttgct ggcttcgttt
     8761 tgttcgaaaa aacggattga tcttgaagtc agaaaacacc caatctgttg cagctaaata
     8821 atgttcttcc ataaaacgag agctgattag atatcggcgg tgcttatcga ctagttcccg
     8881 ctgttttttc gttaattttg catagatctc ccaacgttga ctgcttgtgt attgtttaga
     8941 aattttgatg ggatagcttt tgctgatttc ttttggaaac cattcttcaa agacggattg
     9001 ccattcttcc acggctgttt ctttcctttc taattacaaa aagctggcta ctaacataac
     9061 gttagcaacc agccagtgtt tcttgctaaa ttagtgagtt gttccggcat ttccggaaat
     9121 atcttcttta ttttctactg ctgcttcaac tgcataagtc aaagaagaag caatgtcttc
     9181 taaagacata gaaggcgtac ccactggacg atcgatcact tgatcgggtg agaatggcac
     9241 gtggatgaac ccacctcgaa ttgccgggaa ttgtgtttcg atcaaatgaa gcaaacgata
     9301 catgatatca ttgcagacaa atgttcctgc tgtataagag atgtacgctg gtagaccatg
     9361 atcttgtaca ttttttgtca ttgctttgat tggcaatgag gtaaagtaag cggctggacc
     9421 gttttcttct aaagccgtat cgaatggctg atttccttca ttatcaggga ttcttgcttc
     9481 tgctagattg attgcgacac gttcgaacga gactgctgac cgcccacctg cttgtccgac
     9541 acagatcacg acatctggtt ggtgctgttg gatggcttct ttgactactt gactgctttt
     9601 ttcgaatacg gtcggtactt ccactttgat gatttcagca ccgctgattt catctggcat
     9661 tttttttact gcttcatagg ctggattcac tttgtcccca ccaaatggat caaaacctgt
     9721 tactagtact ttcatctgtt gttcctccgt ccgattgatt taacatatgg ttatctttta
     9781 tcataccatt ttccttgaac agcgtaaata aaggaaacaa tagtttaaat aacataacag
     9841 atcaaactta atatattctt ataaaaaaat agtgttccac tacaatgtta gaagaggttg
     9901 cgacaattat tctgtcacaa cccctctctt ctattattta aatagaatca tataagcaat
     9961 ttggaaaact agcataaata acgcaataaa caactggttt ttgatcactc cgtatttgtc
    10021 tttcatctcc agcatcgcta caggcacgat attgaagtta gcagccatcg gtgtcagcag
    10081 ggtcccacaa aaaccgcaag tcaatgcaac cattcctatt aacgctggat tcgctccatg
    10141 actaaatacg aatggtgcac cgatcccaac cgtcatcacg gtgatggccg caaatgcatt
    10201 ccccatgatt accgtaaata tcaccatgcc aagagcgtaa atgatgatgc cgatgttcac
    10261 atttccttct ggaacgatcg tacctactgc attggaaatc actgtcccaa ctccagcgct
    10321 tgtaaatacc gcacctagag aagctaaaag cattggcaac atgcttaacg gccctactgt
    10381 gcccagcata tctgctgcat catctaaaaa tgtacttggt cgattatctc gagaaaagaa
    10441 catcaagatt agcatggctg caaaaacacc gacgcccacg ccgactaaag cacctaaatt
    10501 ggtaaataga gcaaacaaga tcgcaaagac accgatactc aaagctggaa taaaaatttt
    10561 cattcctagt ttgtctgaca ttttttccat atattctttt gatggaagcc ggctttctcc
    10621 tttgctgact ttcttagcaa ttgctggtat ggtcatcgca aagatcaagc caccgttcac
    10681 gattgccgga agccatcttc ctcctgcaat aactacccct aagaccgtcc agaaaaaggc
    10741 tgacccataa cgatgaggat tggttttatc tgttaaattt cttactccag tgtaaatcaa
    10801 tacgagtccc atcacgatat aaaggatctc cagtaattta tcgcctaata aaatatcagg
    10861 atttgtaaaa aagtccatct tattgcccct ttcctggata atatttcttc gctaatttct
    10921 tttctttaag atagaagtag acacttgcca caactaaagc cgtgatagcc actggaactt
    10981 ccactaaagc aagctgtccc aatgttacgt catatcctag atctttcagt gttgattgga
    11041 ctagcaacgc ccctgctcct ccgatgaata gtacttggcc aaagaaccag cagacatttt
    11101 ccatagctga agccatacct tttagttctt cttcatgctt aggatggact tctaaccctt
    11161 ttgattcgat ggtccccaat gccatcggta aaatgattgg acgaacaaat ccagcaactc
    11221 caccaaaact cacgttaaaa gccgcaaaga tcattcgaaa gatcccataa atatctacaa
    11281 tcataccagc agatactttc ttgaatcgct tgatcaagga agccgctgat tctttcagac
    11341 catttctttc aagcgttcct gttgccaaca taatgatgat aaaaatcgcc atcccgcgat
    11401 tgtttacaaa acttgtacct aaaagttcta acattccttg aatgccaaga ccgccagtca
    11461 aagctgtaac aactaaagca accattacga tcaatatcga gtctaattta aatgcaaacc
    11521 cgagaataac aatcaagacg cctaaaaggc taagataatt ttccatatat tttcctccat
    11581 aaaatgacaa tattttttta attataaagc aaaacacata aaaaatatag ttgttttctc
    11641 acgaaataga cactattttt aaatattttt cgttattttt ttatcacaaa aattatctta
    11701 cttattgtaa ggtaaagctt tttttaattt attgcccgat aatatataga aataaggtct
    11761 agttactgtt ttttttaaat gattaataaa taacaacttc tttctatgaa attgcaaagc
    11821 attcatcttc ttttccgcta acgatatatc cgtcagtgct tggtacactt tactaaaaag
    11881 tatgagattg ccgatatctg gataggtgtg ctatactaca gaaaaagata tacaatctgc
    11941 caccgggtag gataaagagg atgatcattc cattaggtct ttgaagggat gattttcctc
    12001 tttttgtgta tttttttata gttaaggagg aatgtaagta tggcatggat ggaattaatc
    12061 atagcaggaa ttttggaagt attctggtca acgatgatga aatggagtga tggtttttct
    12121 aaaatcaatt attcttttta cacagtgatt ggcatgattg ctagttttta ctttttgtca
    12181 aaggcaatca aaagtttgcc gatgagtctc tcttatccta tctggacagg gattggcgca
    12241 gttggttcgg tcataattgg tgtggtcttg tttcatgata agctgaatct ttccacttgg
    12301 ttctttgtgg ggatgctact catcagtatc attggcatca agattactag cggccactag
    12361 acacttggaa taagtactga tcagaaaaaa taagcctttt tatttaatat tcaatttttt
    12421 tatgaaaaaa taagaaataa gtccaatgac ctagcgactt ctccactcat caggtgtatg
    12481 cttgtactat ctatagaaaa ggagtgaata tttttgaaaa gtctttcggt ccaagaatta
    12541 tccaagaact ttggtcacaa acaagccctc agcgatgtca gttttagctt atcccctggc
    12601 aaaatcgttg gattagtagg tcctaatggc gctggaaaaa caacgatcat gaaagctatt
    12661 ttaggactga tccattactc agatggaaca atctgtattg gtgaaaatga gatttctccc
    12721 tctagtcata aagggttgga acaagtagga gcattgatcg aatacccggg tatctatcca
    12781 ttcttaacag gctatgatca tctgaagtta ttctctgaaa ccaacgatgt atctgctatc
    12841 gacactatcg tgaatcagct caagatggaa aagtacattc acaaaaaagc gaaatcctac
    12901 tcgttgggaa tgaaacaaaa attgggaatt gctcttgcct tactgaacca tccgtctatc
    12961 gttattttag atgagccgat gaacggtttg gatccacaag caacaagaga tgtgcgaaaa
    13021 atcattaccg acttggctac tcagggcacc tctttcttga tctccagtca cttactcagc
    13081 gagcttgaaa aaatggtcga tgagctgatc ctgatcaatc aaggaaagat catcaaacaa
    13141 tgtacaatgg ctgaattgaa ccaaacagcg caagatttca tcgttatctc tacaacaaat
    13201 gatctagctg ctcgaacgat cttgacagaa gctggatata ctttggaaga tcctgataaa
    13261 atcaagcttt taaaagaaaa cgaagaatta ttaggaaccg tgatccagct attgtctgca
    13321 caaaatatcc atgtgacaga cgtccagcat ctgacgaatg atttggaatc ttctctattg
    13381 gaaattctgg attcagtaaa gggggaagaa gaaaaatgac attgcttgta aaacaagaat
    13441 tatttaaatt gatcaagaaa aagtcaactg ctgttttatc tgttctatta gttgttttgc
    13501 tcataggaac agcacttcta gccaaaaaat acacgacgat cattgatcca gttgaaatga
    13561 ctgctcagct ttttagtgcc acatcttgga ttgtctttat catgattgca gctgcaagca
    13621 cgatcatttc gatggaagca caatatggta cattgaaaaa tctcctttat cgaaagtatt
    13681 ctcgaggaga aatattagta agcaaatgga tcacattagt tatttattct gtttatttat
    13741 accttttagc tattattgtc actgtgttga tgaaactgat tcttttccct tcgatttcct
    13801 tcacggagaa ggtttctact ggtcaaacac tgatccaaag cttgttcact tatactttgg
    13861 gtagttatat cggtttatgg ctgattttaa gtttagtgtt gatgattgct tgctttatca
    13921 atagttccgg cgcatccatc tcagcaggaa tcgtctttta ttttgcttcg tcaatcatat
    13981 ctggtatcct tattgcactc atccaaaaat gggagtggat caaatggaat ccgatcagta
    14041 tgttgaatct gcaaaaccaa attggaaacg aagagatcat gaagcaattg actcatcttt
    14101 ctactaatca aatgctattc ggtaatttag cttacatcgt tttgttctta gcattaggat
    14161 atctcgtatt taagcgaaaa aatgtatgat gactcatcaa aaaagaggct gtgaaagaga
    14221 cgttcagcct tattgccgat tggctgtctc ttaaacaccg tttattctga aaaaggagct
    14281 gtgacaacat ttgtgtcaca gctcctttcc tagtatgttt ttgaataaac gacaggctca
    14341 caacctctct ttatacttct tttatacttc tatacgtgaa gcatcccagt ggcaaataaa
    14401 accattgcaa tcactccgac catcgtcaca cctataagta aaatcttatc taagtggata
    14461 tgttgtacag gctcgttttg ctccttacgt gctttgaggt aaaaataaat gcctggcaag
    14521 aaaagaacaa gaacaagcat tacttcatta aaggctacga ctagcatagc ccatacttga
    14581 aaggcacttg ctaaaagccc tactaaaaat tggacccatt ctttccgctg ataagaaagt
    14641 ttcatttggt acaatcctaa gaaaagccac gtgaagaaaa tagctgctgt accaagtgtg
    14701 taagcaaagt tataagcact gtcagtgaat aataatgaaa gtaaaaagac attcgtacat
    14761 aacgtcgtca atacgatagc ataagttggt gccccatttt tgttgagttt tccccatgct
    14821 ttaggcaaaa gtccgtcttc agccatgttt cccattgttt caatcggtaa gatcgtccat
    14881 gagagccaaa caccaactaa agaaatgatc aaaccgccgt tgatcacgac tgctccccat
    14941 ttaccaacca tcatttcaaa cacatagccc atagcaggct gcgccttgat cgtttgcagc
    15001 tgattcatcg tcattgtccc atatggaagc atggaaacca agacgtaaat aataatcaag
    15061 ccgaatatcc ctagaatcgt tgctttccca acatctgatt gtttttttgc tcgtgaacct
    15121 acgacagagg ctccttcaat accaacaaat acccaaagca tcaccatgat gcaactcaat
    15181 acttgactgg aaaacgggat cggctgtcca ttcgcattca atataatgtc gctagaaaag
    15241 ttatcaatga attgttggat cgaaaacgtg ctgatagcta ctacaataaa taaaaataat
    15301 ggcactaatt tacagaatgt gacgatagca ttgacgaaac tagcattttc gactccccga
    15361 ttcactagcc atgcatatcc ccataaaaag actgtactca tcacgatcga tgccagattt
    15421 tgcccacctt caaatactgg gaagaaatat cctaatgcgc tcatcaacaa tgttgcaaaa
    15481 gctacgttgc ctaaccagca tgtgagccag taaccccaac cgctgataaa accagcgaaa
    15541 cggccaaaac cttcttctgc gtaactaaag atcccgcctt ttaaatctgg acgtttttta
    15601 ttgatattat tgatcgacaa ggagagcatc aacattgctg ttcctacgag tacccaactg
    15661 aaaatagctg ggccgccagc cgatccggag atgtccgtca taataccaaa tacgccacct
    15721 ccaatcgctg aaccaattac taaggcagca agtggaatta aaccaattcc ttttttctgt
    15781 tgctctgtat ccatgtaagc atcctccaaa ataaaaccgc ttttatcaaa aagtataaca
    15841 aacctttttt atttttactt aattaataaa aactttaata gaaatataat tctaccggct
    15901 tttttctcat tatacaagca aagcgcctag tccctttcca aattacacca ccaaaaaact
    15961 taaaaaagat gctatactaa aaggaaagaa ttggaggatg atccatgaac attttatata
    16021 tatcgatttc aggaaatacg cgtgcctttg ccaaacatct agcagaatat gctgaaaaaa
    16081 tgcatgcaga agatcctgtc aatcctgaag ttactttaaa agaaatccat gaaaatagtg
    16141 attttacgaa agaaacagaa ccatttttta ctttcgttcc tacttattta gacggcggaa
    16201 atggtttaga taacggtgat acagaaatct tgaccgaaac gatgcgtgaa tatctggaac
    16261 atgaagacaa tcataaactt tgtcttggtg tagtcggtag cggaaataaa aacttcaata
    16321 atcagtattg tctaacagcc aaacaatatg cacaaacatt tggctttcct ttcttggcag
    16381 attatgaatt acggggaaca ccatctgatg tgacacgaat ttatcagatt ttagcagaaa
    16441 acaataaata ataaaaaaga agaagctgaa aaatagattt cagtttcttc tttcgtttct
    16501 attgtttcta tcatattaag ctttgacatc catcacaggt gcttttgctt ttgctttacc
    16561 tgttttttcc aagacaaagt tttttacacg atccatattg gttaccaaga cgatcatgga
    16621 tgtttctttg cctgctgctt tgatcgcttc taagtcagct tctgctacaa gcgtatcagg
    16681 tgtcacttgc tgcccttctg ttactttcac atcaaatggc gtaccgccta agtcaactgt
    16741 gttgattccc atatgaagca agatttctaa accatttggc gttgtgatcc caatagcgtg
    16801 tttcgttggg aagacagagc tgactacccc agtaactgga gaatagatat gtccgttttc
    16861 tggttctaca aagtagcctt cacccatcat cttttgtgca aaaactggat cacttgcttt
    16921 atctaaagaa acaactgttc cgtcagcaac tgatgagagg atagtcacac tttcagctga
    16981 agtttgaggt actacttttt caggcacttc atttactgtg gctgtttcag tcgctaattc
    17041 ttctttttct aaacggtctt taggaatacc gaagaagaat gtagcaacga agccaccagc
    17101 ataagctgcc aataatccaa ggatgtagcc taaccattta ccgtcagaga tcaatgggat
    17161 caaagcggct cctgaaggtc caatagcgat agccccgaca tttccgatca ttccgatcac
    17221 tgccccgccg atacctccac cgatacaagc agtaataaat gggcgtccta gaggtaatgt
    17281 tactccgtaa atcaatggtt cgccgattcc taggatcccg actggtaaag ctcctttgat
    17341 catttctgtt aattctttat cttttttgca gcgaatccat aatgccaatg ctgcacccac
    17401 ttgtcctgca ccagccatcg caagaattgg aagcaatagc gtacgaccag tttcatcaat
    17461 catttgcaca tggattggag tcaaaatttg atgcagtccg aacataacca tcggcaagaa
    17521 taatgtgcct agaacgaagc cggcaaatgc tccaccaacg ccaagtaccc agttgatccc
    17581 accgaccatg ccatcagaaa tgaaacctgc taaaggcatg atgaagaaaa tttcaatcag
    17641 accgatggca atcaatgaaa gagttggtgt aacgatgata tctaccgcat caggtactac
    17701 tttatgcagt tttttctcaa cgattgacaa tagccaaaca gcgaagatga cacctaggat
    17761 cccaccttgt ccagctgcaa gagcttcacc agtaaataag tttttcagtg gtgcttccgg
    17821 attcatccct gtcagcatca caacggcccc gataactcca ccaagagttg gtgttgcacc
    17881 aaaaacttgt gcagcattga tacctgtata gataactagg tagctaaaca tcccgttttt
    17941 caagatgttc atcacatcga tatattgttg ccatgttgct gcatcaagtg ttccggctgt
    18001 gactaagttt gctaaaactg cggcaatccc tgccacgatc ccagtaccga caaatgcagg
    18061 aatcattggc acaaagatat tagaaatgtc ttttaatacc gatttgattt tagatggttt
    18121 ttgtttcgat ttttgtgccg ctttcatttc ttgtgcccgt tcgtttacac ggtcttttcc
    18181 agatgctgat gaatttgctg tagctgtact tacagaagaa agtttttctc ctaatttcac
    18241 gcctgccaaa tcaaccattt gctgtgctac tttgttcact ttcccaggtc cgatgatgac
    18301 ttgaagctgt tcatcttcta ctacaccaag cactcctgga atcgctttta attcagagac
    18361 atttacaaga tcatcattga tgatcttcat acgcacacga gtcatgcagt ggacaatgct
    18421 ttctacattg cccatgccgc ctgccccttt ataaatttgt tttgccagtt cttccaaagt
    18481 cagttcgttt tttgccatgg tcttttcccc ctcataaggt cccttttaca aatccgtttg
    18541 cttcagctaa ttttgcttga gcttcctctt tatcactatt tgtcaaaatc atgacgatag
    18601 ccagcttaac attttgatct gcttcttcaa agtacttttc agctgtttcg taatcagctt
    18661 ctgtcgcttg catgatgatt cgttttgagc gttcgattag tttttcattt gttggtttga
    18721 catcgaccat caagttattg aatactttac ctataccaat catactgata gtagaaatca
    18781 tattcaagat aagtttttgt gctgttcctg acttcaatcg agtagagcct gtcaaaaatt
    18841 ctggacctgc atcgacttcg attgggaaat ccgcgtgttt actgatttcg gcttgtttat
    18901 tgcaagaaat cgttcctgtg acagcaccga tcgattttgc gtaatctaat ccaccgatca
    18961 catatggtgt acgaccgcta gctgcgatac caataactat atcatttttt gtcaaattca
    19021 gcttgattag atcttcttgc cctagctcat aagaatcttc ggccccttcg acagctacag
    19081 tcattgcttc ttctccacca gcaattagac ctatgaccat ttccggttct acaccgaatg
    19141 tcggtacgca ttcagcagca tctaacacac ctagtcttcc acttgttccg gctcccatat
    19201 aaatcagacg tccacctttt ttaaaggact caatcgtgtt agcaatcact ggttcgatac
    19261 ttgtcagttc tttttcaacc gcagcggcca ctttctgatc ttctttgttc attagttgaa
    19321 cggcttgaga aatactcatc tcatctaatc caaaagtttc ttggtttctg cgttccgttg
    19381 ttaggttctc taaattgatt ttgctcattt ttatcttcct tcttttctta taaattgata
    19441 gttcatacca gctttgattt ggttgatcaa tggtagctct tctttgataa ctttagctac
    19501 tacattcact ttttcatccg ctggcaaatc atatttggtt aattggatct cacccatata
    19561 gcgcaaatac ttttcgttat ctaaagtaat agaccctttc atacgcgtag ctgtatttct
    19621 tgctgggata ggcggaatct ctcgaaaacg tgcatctacg cttcgtatga catctcttgc
    19681 atcgtcttgc cgattcgtat gcttccctaa tatatattcg taaaattctt catctacagg
    19741 ttccgtatgg agcaagactg tctgttcttt ttggaaagaa gcaaattgct cctgaacgtt
    19801 ttctgacaga cctgcatctc cgatgtaaac aatatccgtg ttacttgcta atagatctag
    19861 agcgcctgca agaggatgga tccctcgatg ttcttccaaa gttggcaatc cttgatatag
    19921 tgggcctctc aactctgtat ctcctggtac aaaaccttgg acaaggagac cttgaatttt
    19981 gagccattga ttttttttct gataccattc tttgtccagc cctgtttcgg gacgtggata
    20041 ataattatgc caagcttcaa tctgtgagaa atcagcttct gcttctttca attcatcgat
    20101 atctttaggc gtgatcgtgc tagcattcaa actgattttc aattgatgtg accagtcggc
    20161 aatctgctga ttggaaatat gataatccat tcttaaacct gttacaccaa ttgctttcaa
    20221 aggcgttaga tcttctaatg aaaaacccgc tcgttccaat gcctctcctg aaatatcgac
    20281 catcaattct agtttattct ttttcgcttc gcttcctagt tcgatcaatc gcttttgata
    20341 tgccgaaaca tcatcttctg gtatatgcat ggaagtgaaa ataccgacaa agccattgga
    20401 tgccatttgg cggatatact gtttcttctc ttctgacaaa gaatcgttca taaatattga
    20461 aaagccaaac atattatccc tctttttctg tatccgtctt catttctatg actagagtat
    20521 atatctaaag aaacaaaatt tcaatacttt tattaaaata attaaatttc atttctaaag
    20581 gttgagttta tattatcaaa agaattgtca taacctaaaa aaggcactgc taagcaaaag
    20641 cagtgccttg aaatatttta tttaaataac acaaaaacat aattactcat aagaaaccaa
    20701 ttctgtatta tctaccatga atgtaaagaa cccctcatta ggcatcggat gaaaataagc
    20761 attgatcact cttatcaagg cattatggca aactaacaga tagacatttt cttcgtcttc
    20821 gatgcattct ttcaataaag gaacgatccg tgcatacaca tctaagactg actccccatt
    20881 tgggaatcgt acagcgaacg ctaaacgtgc tttttgaaag ttctcatctt tgcttggcag
    20941 tccatcataa tccccaaaat ccatttctac caatcgttca tcaacggtca gcggcaagct
    21001 gagacgatca gcaactgctt gtgctgtatc tcttgctcgt tgaagagggg aatggatgat
    21061 tttcgtgatt ggaacaggca aatctactac cttttctgct agtttctgtg cctgcatctg
    21121 tcctttttca gtcagcggca catctgcccg tccgcaaact aatccttgtg cgttccaagt
    21181 tgtttctccg tgtctcgtta cataaagcat gtgattctct ccttcgttgg caaagttccc
    21241 cttaaccata ccttgttgtt cttgagatta caagggttag attctctcaa gagaaataat
    21301 ctcagtagat actttatcca ggaaggtttg atcatgttcc actagtaaca tggcaggttt
    21361 cacgttcaag atcagttgtt ctaattgttc ttgattgaag acatccaaat aattcaatgg
    21421 ttcatcccat gtatatagtt cagctggctg tgataaagat ttagccaatt ccactttttt
    21481 ccgttggccc atactcatct gctcgatctt gttatgaaaa acatctcttt ccatcccaag
    21541 ctttcggagg ttgttcaaaa atgcttggta gtctacttgg tttttctctg caaattccgc
    21601 caacgttcct cgattgtctt cataattttg gcttgcataa ctaatgctca gatgttttgg
    21661 ctggtatttt tctcctataa ccttgccgtt gaatgccccc agaagataat ggataatgga
    21721 tgactttcct gcaccgttag gacctgaaat cgccacccgc tgatgaggct cgattgtaaa
    21781 atgaattggc tcgaataaca gattttcata ccctaattga agatcttcta cgcttaaaag
    21841 tcgcttatgg tgagacgctt ggctattcat cgtcaaagaa tcgatatatt cgatatcttt
    21901 taatagtttt tctttctcgc tgatctgggt ctccatccga ttcacgattg ctttggatcg
    21961 tttcatcgtc cgtgcagcat cagcacccac tgctccttta ttcactcgtc tagattcagt
    22021 atcgatgaat ccgacttgtt tctttgtttt atctccttct cgggaacgag accattcggc
    22081 tttttcagct gctgttttct ttagcctact gacttctttt ttcaattttt cattttgagc
    22141 catttcaaat tcatcacgaa gttttttctg ttcttcatag atagagaaat tcccttgata
    22201 aagttccagt tgactttttt cgattgctaa aacatggtcc actacttcat cgataaatcc
    22261 ccggtcatgg ctgaccacga tgaagccttg ttttttcttt ttcaaataag ccgctacttg
    22321 ttttctacca gagatatcca aatgattcgt tggttcatcg attaacggga aatgagtgtc
    22381 atccacaaat aaaagtgcca gtaggacttt tgtcttctct ccccccgata gtgtgctgaa
    22441 ttctctccat aagatttcag gatctgtttg catcaattgg agctctcttt cgatttccca
    22501 tatctcaaaa tccgtaatat catttaacac gtaataggtt aaacgttctt tatcttttgt
    22561 ctgttgcggg aaataggcaa attcttgctg atggattact tgcccttgat aaggtagttt
    22621 gttttgtaga atattcagta aagttgtctt tcctcgaccg tttcgtccga taagtcctag
    22681 tttccattgt gtgtcaaaat ttagatttgc ttgttcaaat aataatgtgc cttggctgtc
    22741 gtagccgaat gtcagatttt ttatttcgat tttagacatt ttccatcacc tcgtaaaaaa
    22801 agaccagtcc tattttcaga actggctaaa gaggatgcaa gggttggata cacacaaaaa
    22861 gacccataca tcgaaaaaac caagccaatc ccgaaaatct gcacactgct tccttgtctc
    22921 cacaaggtac agtctgaatg cagctttcat caatcgactt aatttttcaa tgcacggatc
    22981 cctcactttg tcctatattt gaaattacga tagcataaag aaaatgattt tgtcaactac
    23041 ttcgggagga tggtgaaaaa tctgctaagt gtctgtccta agatttttgt tttttctaat
    23101 gtttgcctgt gttccattgc ttcttctaaa cctattggac ccaaatgaat acttaagaca
    23161 attgggagaa aatcagaaag tccttctagc tcttggtctc tacttccgca aatagcgatt
    23221 attggttttc gatatttttt tgcaagcact gctacaccgt atggaacttt tccgtggatc
    23281 gtttgctgat cgatccgccc ttctcctgta atgatgacat ctgcttgttc gatctttttt
    23341 tccaatccag tgatttggct gactaaatcg aaaccagaaa ccatcttcgc tcccaacaaa
    23401 aaaagggctc caccaatacc gcctgctgct ccacttcctg gaatatcatc taaatccacc
    23461 tcccagaaat cttttatttg ctgagcaatc tttcctgctt gtttatctaa gaaagctagc
    23521 gtcgtatcta ttcctccttt ttgtcttcca aattgccaag cagctccttg ttgacctgta
    23581 tatggattgg taacatctgc agcgataatc aattttactt tagaaacaag aacgtttctt
    23641 cgatcaaaat gaagtttttt agtagataat aaaggatttc cttctgtgta cccttctaaa
    23701 gaagcaccca aggattggag taatcctaga ccaccatcgc tacacccgct tcctcctaaa
    23761 gtgacaataa tttgttctac ttcttgaagc agtgcatctt taataagttc tcctaaggca
    23821 taactggaag caagtcggat agtttgatcc gttggtttat caagtagatc taaccccaat
    23881 gcttgtgcag attcgatgac tgcggtgttt tttccttgcc aagttgtcaa taaatagctg
    23941 atttttcgct gacggaataa gagatccatc ccatcaatgg tacgccatgt tcccctgagc
    24001 gcgtaataga ttgcttctgc agtattttct ccgccatctg caatcggcac attgattttt
    24061 cttcctttac gatcttccca gccatttaga actgcctgat ttagttcaaa tgaagaagca
    24121 cttcctttaa atgaatcaat tgccgccaaa atatccatct gtatccctca ctttcttctt
    24181 aagtaagaca ctttttttca tttttttcaa acaaaacaat gctattttct tccatttttc
    24241 tatatactaa aagggaactc attgaataaa ggagagaaaa aacatgaaaa tcgcaatagc
    24301 tggggccgga gcaatgggca gccgaatcgg attgatgcta catcaaagcg gaaatgaggt
    24361 cctcttgatc gatcgttggc ctgctcacat tgaagccatt cgtacaaatg ggttgattgc
    24421 tgactttaac ggtaaagaag tggtcgcaaa actgccaatc tattcaccag aagaaatcat
    24481 cgaaagcaac gaacacgtgg acttgatcgt agcattaaca aaagccaatc aattagatga
    24541 tatgttttgt tcgatccaat ccattattac tgacaatact tatgttttgt gtttactaaa
    24601 tggattaggt catgaagatg tactggaaaa atatgtgcca aagaaaaata tcttatttgg
    24661 gatcacgatg tggacagctg gtctagctgg tcccggaaaa gtcacattgt taggtgatgg
    24721 agaaatcgaa ctagagaact tggaaccaga aggcgaagca tttacaaaaa aagttgtaga
    24781 agtctttcaa gaagcaaatt taaatccgat ctatagccat aacgttcgtt attccatttg
    24841 gcgaaaagct tgtgtaaatg gaacattgaa tggtttatgc acgattttgg attgtaatat
    24901 tgctgaacta ggcgcgcaaa aagcggcaga gagcatggtt cgaacaatcg tatctgaatt
    24961 tgcttctatc gcagcaaaag aaggaatcat actagatcaa gaagaagtgt accaacatat
    25021 tgcttctact tatgatcctg acaacatcgg gttgcattac ccatctatgt accaagacct
    25081 gatcaaaaac catcgtttga ctgaaatcga ctacatcaat ggtgccattt ggcgaaaagg
    25141 acaaaaatat gatattgcta caccatattg tgcctttttg acccaattag tccatgcaaa
    25201 agaaggaatc cttggcgcag aataaaaggc tctctgatga gaatcagctg aatcagcagc
    25261 tggttctctt tttttaagcc caataaaaga tcaaaaagaa aacacaactc tcatgatgcc
    25321 ataagaattg tgcttgtttg tttcagtaca taatctcttc aaaatgtagg ttttttattt
    25381 gttttcaaca gaggagaggt catattcgta ttgctcataa atagtggaat cgttagtgat
    25441 aaatcgtttt gcccaatttt ctgcatcata aaattccaat agctctgata ggattggctt
    25501 aaatggtgta tgcagaaatt ccggtaattc atctaaatca cgttctcgaa gcaaaaaaat
    25561 attttcagga cgataaaaat gataatgagc aatcgcttga ttatccgtca ctagtttctt
    25621 ttgaaaatac atggattcaa atgtccgcaa agtcactcct tgctgaccct cccgcaacag
    25681 ttccagaatc ccgcgcgatt cccctgtttt tttcaggtac tcttcataag taagatatcc
    25741 aggttgttca ttccctcgat gtggaagaat gaaatagttg gtcgtaacat ctctttttat
    25801 aaattcctgc ttatagcttt ctgctcgttc ttttctccca ttattcgttg caccaaaaaa
    25861 tagatccgtc tttggttcgc tagaagaaaa attcatatgt ttcgaataaa atgaactatt
    25921 atgtttcagc ccaagttctt ttgcttccaa aaaatcaaaa tgataaatct catcgattgc
    25981 cggttcatct tgtgcctgct tcagcatcgc ctcgtgttct gctttgaagt gattccaaaa
    26041 aaataacaca atttttgcat tggtaaatgg gcgcacgcgt cgagccatct ccatatcaaa
    26101 tccataatct aaaaaaacga tcagctgata atttgccaac tgttgtctag ctgatttaat
    26161 gaattccgac tgtagtaaat cttttccgga ccaaacatct aaagagcgga tggaaggcaa
    26221 aaaataaagt gatttatttt ttgcaactag cagtacgtca tttttgttca tcttttccgc
    26281 ctcactttct ctgtcacttt ttcctatgat agcctgttta aatagtaaaa agccagtaaa
    26341 acgtttccta tatttgtatg aaaatttaac atttgtatga aaatatgatg aaataaatca
    26401 ttcttctatt aaaattcgcc taaaagtttt ctgaatagtt gtaattgtct gaaaatttgt
    26461 tatcattagt cattgttaaa tattgctatt tattcttaat ataaattttg attgtgaatt
    26521 taaaagaaag aggtcattta tggaagataa aaaattgaaa aaacaactta gctccagaca
    26581 tatcaccatg ttagctttag gtggagcaat cggtgcaggt ctatttaaag gaagtggcga
    26641 agcgattggg atcgccggcc cttctgtatt gattgctttt ttgattggtg ggctgatttt
    26701 atatatcgtg atgaaaggtc tgggaaaaat cgttttaagc ggtggcgaca cgcatcacgg
    26761 attatctggt ttgatacgcc cttatctagg tgctcattct gctgatttta ctgattgggt
    26821 ctactggtct atgtggatta tcaatatcat cgctgaagct gttgcagctg cttccttttt
    26881 gcagttgtgg ttcccgcaca ttccagcctg ggtatttgtt tttatgttgg ctgttttaac
    26941 tacgatcatc aatctttatt cggtacggtt attcgcagaa acagaatatt ggctggcttt
    27001 tgctaaaatc agtgtcatta tcttactgat catttttgct acttatcttg tcggtcagca
    27061 aatgttgggc acaggcgttt tccctaccct tcagcaattg actgaccatg gtgggtttac
    27121 tcctcatggt atgaagggaa tcatcagttc tttgcttgta gttatctatt cttacggcgg
    27181 ttctgaactg attgctatca cggtaagcga agcagatgat cctaaacgtg cgattcctaa
    27241 agcaatcaaa ggtgtcatgg gaagaatcat ttccttttac atcattcctt tgtttttgct
    27301 tttgattctt tttccttgga atactttagc aggcacgaat gtcagtcctt ttgtgatggt
    27361 atttgaaaaa atgaatatcc catttgcagc ggatatcgtc aattttgtga ttgtccttgc
    27421 tttgttctca tctatcaatt cgggtgtgta tgcatcttca agaattttgt tcttccgttt
    27481 gaaggatcga aaaggttcct ctagaaaact agctgtttta aacaagcatc aagtaccgca
    27541 acgtgctgtt ttattttgta ccagtgttct ttatcttggt gtagctcttt cttattttgt
    27601 cggtgacaaa ttatttggct atctggcagg ttccctttcg tatacagtat tattgatctg
    27661 gatcattatc agtgcggcat cctttgtact ggcactaaga aaaggaacat tatgggataa
    27721 aggaatcagc ttttttgcat tagctgtctt aggattgatt ttccttggta tcctgttcac
    27781 gaactccatt ggggtaactg tattgactgg cctgctttac ctgttcattt atttcagtta
    27841 tcaaaaaaag aatgatgcgt tcgtattgac gaatgaatga aatcgataga aaattttatt
    27901 ttatttatgt ggaatagatg gagctattga agaaaggagt tgtgacaaaa gtcttgttgc
    27961 aactcctttt tccgaataaa cagtctcatg acctcttggt aaacggtgtt caaaaaccct
    28021 ctgtgcaaaa taattgattg ttctccatgc tcatgacatg atagaagaaa ggaatgaaaa
    28081 aaaggagttt gttttaaatg aaaaagtatt ggaagttttt gttgatgatc ggtgtttcaa
    28141 cggtagttat gtttggtatg atgtacttga atgtctatgc gctcgatcat atcttcttca
    28201 gtcgtacacg agtattcatg gcgttgatga tgggtgcagt catggcagtc atcatgctgt
    28261 tgttcatgtg gaaaatgtat gaaaacaaaa agataaatgt tatgatctta gccgctagtc
    28321 ttcttgtttt tgccggttcc ttgtttatgg tacgaagcca aactactgtc aacgacacag
    28381 cttggatgaa ggccatgatt cctcatcatt ctatcgctat cctggcaagt aaacgagctg
    28441 atttaaaaga tcctgaagta aaaaaattag cggaagaaat cattcaggca caagaagaag
    28501 agatcgacaa aatgaaaaaa atgatcaaag aaatggaatg accattatcc gtccaaataa
    28561 aaaaagagga tgttccagaa gttatcagct tcaagaaata agaagaagct acttctggaa
    28621 cgccgtgaat aaggggttgt gaaaaagctg ccctgcatca agtaataaga acagccaaac
    28681 aaaaatagct tctcctattt ttcgtttggt taggcttatt accgcagatg caagcttttg
    28741 aacaccgttt attaagaggt tgtaaaatca gcgttctgac ctgagtatta gagagacaaa
    28801 tggaaaaata gttcctcata ttttgccatt ttttgagcta ataccgaggg tcagctgatt
    28861 gaacaccgtt tatcgagagg ttgtgaaaaa gtcgcttagt ttcgcgtatt aagaaaaatt
    28921 ttgtgaaatg gctttccaca tttttgtata aatttggctt aataccgaga aactggcttt
    28981 tgaataccgt ttattcgtaa aagggattgt gacaaaagtc ttgtcacaat ccctttttat
    29041 gtttttattg ttctaattgc gctgtcttgc ttactgcttc ttgcggtttc acaaattttt
    29101 ttgagattcc ccaacctgtg aaggcactga ccatcgaaaa cacaggagaa agcaaactga
    29161 aaaatacgaa tggcaagtaa gtgagtgtag gaataccaaa tgtacttgct acgaaacttc
    29221 cggcaattcc ccaaggcact aagtagttga ttactgttcc accatcttct agcgttctac
    29281 ctaatacagt tggatcaaat cctgcttttt cataagtttc tttaaatgca ttaccaggca
    29341 gaataacaga taggaattgt tcaccaataa aaatatttac tccgatactt gtcatcaatg
    29401 ttgtaaaaat caaatttggt gtgttcgtca tctttcttga tactcgttcc atcacggttg
    29461 agatcaagcc aaattcgatc aacaatccac ctaatgacaa agttagaata atcaatgaca
    29521 cagtaggcat catactttcg attcctccgc ggctaagcag tgaatcgatt tgttggtttc
    29581 cagtatttga aacaaaccct gattcgatga ccccagccaa cttcgttaag gaagtttgtg
    29641 ggttttgaat aaaaatcatt cctactgcta cagcgatatt caacaaaatc gttaaaattg
    29701 ccggcacctt tttccatgca cacagtaaca ttaaaaataa aggaatcagt gaccagattg
    29761 aaatagtaaa gtttgcttct agaacatcag tcacttcacg aatagatgaa agacttgcgg
    29821 ctttacttgt gtgtcctaaa atcatgaata aaaagaaaga aacaacaaat gccgggacag
    29881 ttgaccacat catatgcttg atgtgtttga acaaatcggc atcaacaata gctgctgcta
    29941 gatttgttga ttcggataat ggagacatct tatctccaaa aacggcacct gaaacaatag
    30001 ctccaacaac cagcgctgga tttaagccta gtgttgtccc aataccgaaa aatgcaatcc
    30061 caatcgttga cataacagta aaggcactcc ctacagcgct acctacgatt gcacacacaa
    30121 caaatacaga agggacaaac cactggacac tgatcaattt gaacccaatg accattagag
    30181 ttggaatgat ccctgcttgt atccatacag caatcaatga accgactaaa ataaaaataa
    30241 agattgggat gattcctggt ttgatgccat tgatgattcc ttcgtgcagc caatctgtcg
    30301 ggtatctttt tatcactgca tacaacatga ccattccgat cgctgctaag atcgtgatat
    30361 taggtgagac ctttaatccg acaacgccaa tcgcaatgcc taaaacaata accattaata
    30421 caagtgttgc ttctaaaaaa cttggtgttc ctttttttcc catgataatc tctccttttt
    30481 tagttgttct tatgttctaa aaaagttaag atatcggatt actccgccgc aattcatccg
    30541 cgattcctcc tttataaaaa taaaaagacc tgttttaaac taaggacgaa tgactccgcg
    30601 gtaccacctt aattaaaaac agatctgttt ttcactttca aacttttatt caaatgtatg
    30661 gactttccat gtaattcgtc aattaggctt gatcggttca cagcgaccac cgactttctg
    30721 aacaaaacac ctaaccgcta ctgcgtgaaa agttgacttg tacgaagttt accttccata
    30781 agatcatttg tcaatgaaaa agaaaatatt ttttcatttt tctgaaaatt atttttataa
    30841 ctttcacaca caagtttatt ttttactaga aagtagcgcc ctcttgtttt tttcttgcta
    30901 ctatttcttg atgttcttgc ttgattcttt ctaatagctt tggctctttc aacagatcaa
    30961 gagctgtatt ggcgagtagt tctgctgcaa tcgcaataga agcaaggcct ttgtcacttt
    31021 tagcagcagc tttgaattct tctgtgtgtc cggcaatata tgtctcagag attgctaccg
    31081 taggctggat tgttggtatg acttggctga catttcctac atcagaagaa ccgagacttg
    31141 ttctttgttc cgtttctatt tcttcatctg gaacacctgc ttcttttgca tgctggaaga
    31201 ataagtcatc aaaagaagga gtaacgatga catcatcaac tgcattttgg aacaatccaa
    31261 actcaaaagt cgtgcccgta cttatcgcag cacctcgtac gatattttcc actttttcat
    31321 atactttatc taatgtttgc cgatttcctg cacgtaaata gaaacgtcca gcagcgtaat
    31381 ctggaatgac gttggcagct actcctccgt ctgtaatgat cccatggata ttgacatctt
    31441 ttggcaattg caagcgtaga gcgttgattc cattaaacac ttggatcaat gcttccaaag
    31501 catttactcc tttttcaggt gctgctgctg catgggaagc gacaccgtaa aatttgatgt
    31561 cgactggatc attcgctaaa gattctgtcg ttttcccata acgaaaagct ggatggacgc
    31621 ataacgctac atcgacatcc tcaaaaaaac cttctcgaac aaagctgcct ttagctgatc
    31681 cgttctcgcc cccttcttcc cctggggtgc catatacacg gatttctcca ccagtttcat
    31741 caatgaattg cttcactatg ctggcggcta atacggagta agtaccaaac aaattatgcc
    31801 cgcatgcatg accaatacct ggtaaagcat cgaattctgc caaaaaggca attgtgggac
    31861 cgggtttatt ggaaatataa cgtgcatcaa aggctgttcg gtgtccagct acttcttttt
    31921 ctacccaaaa cctttctttt tctaattgtt taatcaacgc tgctgaggaa taaaactcat
    31981 agttacttac ttcaggatgt tcgtggatat ctagagcaag tgcttgatat tctggtaaac
    32041 gatattggat tagatccttc aattggtttg ttgagattgt tgttgtcata aaaaattcct
    32101 cctatgctag tcatttttct tattttctcc cgaatgtttc ccatgcaggc acgcttgatc
    32161 cttttgatgt tttctcgatt actttgactg tgtcttctgt ttgataagcg tctactattt
    32221 tttgatacgt tttattgttt tcatcttctt ttcttgcaac gatgatattc acataaggac
    32281 gtgcatggtc atccactggt tctaagaaga tggcatcaga agcaggatta aatccagcat
    32341 ctacagctac accgctattg atcactgaaa tgtctacatc tgacaaagca cgtgctgttt
    32401 gggaagcatc taattcagaa atgtctagat tttttctatt ctcggtaata tcagaaacag
    32461 tgggcgcttg tccttttgcc ttatccactt tgatcaatcc agcagtttgc aataacagaa
    32521 gagctctgcc gccatttgta acatcattag ggattgctac ttttgctccg tctttgatat
    32581 cagctacatc cttcaaagtg ttagaataaa ttcccagcgg tgcattgaca gtatttccga
    32641 tcgatactaa atcagttccg tgttctttat tgtaattgtc taaaaagaat tgatgttgga
    32701 aagaattcaa atcaatcgat ccatctgcta aagccacatt tggttgattg taatctgtaa
    32761 atttcacgta ttccaaatta atgttctcct ttttcaaacg gtctttcacg ttgtcccata
    32821 catctgtatc ttctccaata atccctagtt ttacgatagt ttcttttttg tcagttgtat
    32881 ctgcttttcc ttggctacac cctgccaacc aaataattgc tacaaatgta atgactacaa
    32941 aacgaataat ttttttcatt ttttctcctc cactttcaat gtgtaatttt tttaatcagt
    33001 tgattactga taaattgact taaaaaaact aagattagaa tcaataatgt agccacaatc
    33061 gttacatctg tttggaatcg attataccct ctcgatatag caagattccc taatccgcct
    33121 gcacctactg ctccagccat ggtagtcagt ccgatcacgt tgatgatagt caacgccgag
    33181 acccgaatga taccaggcaa accttctaac aaatacacac gtaaaatgat accgattgga
    33241 ctggttccca tcgcttctgc cgcttcgatc accccaggat caacttctag cagtgcgttc
    33301 tcgatttgac gagcaaaaaa cggaacaact ccaaaaatca atggcactaa agctgctttc
    33361 gcaccaatcg tcgttccaac taagaaacga gtagtcaatg ctaaaagaga aagcaagata
    33421 atgaaaggga tggaacgaat gatattgatc agcttatcaa gtatttcaaa tagcagacgg
    33481 ttagctagta atccattagg gcgtgtcact actaacgtca cacctaagat gattccaatc
    33541 atcccgccaa tgaatgctgt ccaaaaagac atatatagtg tttgcttcgt cgcttcgaca
    33601 aattcatccg gaatcaaata aacattgggc aaatatgttt taaagaaatc agtcatttta
    33661 tcttcctcct tcgatcactt tgatacgact atctaaatcg tttttttgta aaatatttat
    33721 ttttacacca gatttgatca aataatccaa tgcttttttc cgctgtttgg tttctccagc
    33781 taaagtaacg atcaaactcc ctaacggcgt ttcttgtaat aactctacat tgccatataa
    33841 aatattcgct gttacttgat atttgctgta cagatgagcg attagaggtt cgttcgtctg
    33901 atttccaata taacttaatt ccaccagcca tttattggcg atctgatcgg caaaagcaga
    33961 atgggcaatg atcgtttcta atgcttggtc aagatgagta gctgttcgaa taaaatcttt
    34021 ggtcaattct tcttcaggat tgctgaagat ctggatgctg ctaccttttt caacgattct
    34081 tccatcttcc ataaccgcta ccttgttgca gatttctttg acaacttgca tctcatgagt
    34141 gatcaggacg attgttaaac ctaactggcg attcaatttt tttaacaatg caaggatctg
    34201 aagggtcgtt ttcggatcaa gtgcactggt tgcttcatca cataataata ccttaggttc
    34261 attcgccaaa gctcgtgcga ttgctactcg ttgtttttgt ccccccgaca gttgtttagg
    34321 ataagcagat gctttttctt ccaaaccgac aagttccagt agttcattca ctttttgacg
    34381 acgttcctgt ttcgattttc cagaatactt taaagaaaaa tcaacgttgt caaaaatagt
    34441 tcggctttcc attagattga aatgctgaaa gatcataccg atggcctttc tttcttttcg
    34501 caattctttg ggagagagct gactcagatt cgtctgattg acaatgactt ctcctgctgt
    34561 tggtttctgc agcaaattca tcacacgaac taacgtactt ttccctgcac ctgagtaacc
    34621 gacgattcca taaacatcgc ctttttcaat cgttaaatct acagaatcta ctgcctgtat
    34681 ctctttttct ttttgtttga aacatacaga aacatctcgc aattcaatca ttaaaattcc
    34741 tccttatcta aaaaaagcgt cctcaagaaa atgaaaatgt cattttcttg aggacgcttt
    34801 tttgcgtgtt accacctcat gttcaagctg tgttcacaca caactcctct tcaagtacga
    34861 tcatactcta gcaagatatc ggtcgcagcc gtcatcgcct tacatctatg ctcgggatga
    34921 attgctcgat ggccattttc caatagtcgt tccttgcttc ttctcagcta ccgaagctct
    34981 ctgtcaaagg ttcttctatc gtacttacca tttcaatgca aataatattc aaaaaaaaag
    35041 tccttttact aacataaact atgtcagtaa aaggacgacg tatcgcggta ccaccttttt
    35101 tcggaagttt ccttccctca agcccaacat ctcaaaaaga gagattggcg ttcgttttaa
    35161 cggtcgaaca gttccgaatt tgcctactta tcgacaaatt attctccaag gccattttca
    35221 gcttttctta cttgactctt ctcaccagcc agagcctctc tgcaaagttt ccaaacttac
    35281 tttccttttc aacgaaatcg atattttgtt gttgggatta atctacatga ggaaaactga
    35341 aaagtcaagt acgaaattca aattattttt tctatattta tttttctgtt tttttattta
    35401 acatttcaat aacagttcga agatcttttc cttccgcaag aagtttcaat ttttcctttt
    35461 cttcgacggt ataatttcgg acaaaactgg aatcaggtat caaaacaacg cctaatcctg
    35521 ctcgtgaagc agctgttgct cctactaaag aatcttccac tgcaaaggct gaactagctt
    35581 ctaatcctgt tcgttccaaa gctgtcagat aaggaatcgg tgaaggcttg ttctccgaca
    35641 cttcgtctcc gaatgtaaac gtgtccaagt aatcagctaa tttaaagtga tccaagatat
    35701 ctgttgctct tttcgtaaca gtggtcgtag caatgcctag tttcatatga cgttctttta
    35761 agtctgccaa tatttctttt gcatatggtt ttaagtggat ggctccgctt gtcagctgtt
    35821 gataaaaata ttcttcacgc ttcgctcgga cttcctgtac tttttcaggg ctacctgctg
    35881 ctttcactaa aatatcaaaa ctttgtttcc agttttttcc gccccaagcg tcaacgattt
    35941 cttttgggat atggatatca aattgctgaa atccccaaag ccagccatca cgatacgttt
    36001 tttctgtgtc aactaacaaa ccatctaaat caaatattgc acctttcatc tatacattaa
    36061 tcctttccaa aacaatacac atagtttagc acgactggtc caaaaagaac agaagcaaag
    36121 aaccagcctt ctcgtttata agagttcttg gaatcgacgg atatagattt tcttcacagc
    36181 tgtcacaagc gccagataag cgatgactgt agcaaataac cataaccagt aattgccagg
    36241 aagtggcatc aagcctaatt cagcaccaaa acttgtaaaa ggaaggacag aaccgacaat
    36301 aattcctaat gtagtgataa caaacatggc aaatgttgcg ttgctttgga taaatggtac
    36361 tttcggtgta cgcagtgcat ggagcactaa ggtttgtgtc catagtgatt cgacaaacca
    36421 tcctgcatgg aataatgcga tgaaaatcac tcgctgtgaa ctatccaatg tatggaaact
    36481 tccgcccact acagcaggac aaataacaaa atacatcaac aagtaagtag taatatcaaa
    36541 tatcgaactt gttggaccaa agtaaaccat gaattcccca atactagatg cattccattt
    36601 ttttggctcg tccaaatatt ctttatccat ccgatcccat ggcaaggaaa tgcaggaaac
    36661 atcatagatc agattcaaaa acaaaagttg taaaggcagc attggtaaaa atggcaggaa
    36721 cgtacttgca atcagcacgg aaaacatatt gccaaaatta gaacttgctg tagccttgat
    36781 atatttcatg atattcccaa aagtttctcg tccagaaaga aggcctcttt ccaaaatcgt
    36841 caaatctttt tctaaaagga tcacgtctgc agattctttc gcaatatcca cagctgtatc
    36901 tacagaaata ccgatatcag ccactttcat tgcaggagcg tcattgatac catctcctaa
    36961 aaatccgaca gtatgaccat ttttacgtaa agctgtcgtc aaacgtgctt tttgctgagg
    37021 attcaatttt acgaatactt catggtcttc agctacttgt gctaattcat gatcactcat
    37081 ttccgagatt ttctcaccgg taaccaattc attgatctct agacctactt gacggcacac
    37141 tgaacgtgta actaattcgt tgtccccagt cagaactttt acagctacac catgttcttt
    37201 cagagctttc aacgcttgtt tcgttgtttc ttttggtgga tcaaggaaag caagataacc
    37261 aatcaaaacc atgtctgact catctttgac tgaaaattct ccaacgacgc ttggattggt
    37321 cttttgtgcg acaccaatca ctcgtaagcc atcttcatta agtgactgta cttttgcaag
    37381 tacggcttct tttcgttctt ttgttaatgg tgtaacagta ccgccaagat caataaattt
    37441 agaaatgttc agcatttctt caatcgcgcc ttttgtgatc atttgtgttt taccagctgg
    37501 atcagcaacc acaacactca tacgacgacg ttcaaaatca aaaggaattt catccacttt
    37561 ttgataattg atcttatctg tatctaaagt ttctgttgct tcatcaatga tagccacatc
    37621 taacaaattt ttcagccctg tttgatagta gctatttaga tacgcatggc gcaaaacacg
    37681 atcatcttca tttccttcac aatccatatg atattcaaga atgattttat cttgtgtcaa
    37741 tgtccccgtt ttatccgtac ataacacatc gattgcacca aagttctgga tggcattcaa
    37801 atttttgatc actgttcctt ttttggccat cacacttgct cctttgacca aattcgtcgt
    37861 aacgatcatt ggaagcattt caggtgttag accaactgct acagatagtc caaaaagaaa
    37921 agcttctagc caatcccctt ttgtaagccc attgatgacg ataactgctg gagccatcaa
    37981 tgacataaat ttgatcagta gcatggatgt tttatggatg cctaattcaa agcttgattg
    38041 aattggtttt tcagatagcg tttctgctac atgaccaaat agtgtttcat ttccaacaga
    38101 aacaatgatt ccttccgcac ttccactgat gacattactt cccataaaga caagattttc
    38161 gtaacttgtt tcgctttgct gatcgtcttc acatactttc gcatgctttt ctactggata
    38221 gctttcccct gtcaatgctg cttgggaaat gaataaatcc tttgcggaca ataaacgcat
    38281 atccgctggt atcatatccc ctgctgaaag ccgaacaaga tctccacaga cgatttcttc
    38341 cataggaatc tctgtgtact ttccattacg ttttacagct gccgttactt tcacaagtga
    38401 tttcagtttt tcagccgctt gattggaacg tacggactga atcaacgtca ttgtcccgct
    38461 gacgataacc atagtgaaga taatggctac accgaaaaga tctttatctc caggagctgc
    38521 taatacatat tccgtgatga atgaaataat tcctaatgcg atcaacacta atgtaaatgg
    38581 cgtgatgtat gctttcaata tttctacaat gaatggtgtt tttttgccat atgaaatcgc
    38641 attttcaccg taattttctc ttgaacgttc gatttgttct tctgtcaatc catttgctga
    38701 tgcatggaat agttcaaata attcttgttt cgtttttcca gcaaaagctg catagatttt
    38761 ttgtgtatct ttcttttttt ccatctcaat ctctcctttg tgtccaaaag acagctgttc
    38821 tcgctgcttt tggtctttag ctattcatcg gatcgataga gaaaaaactg aaaggggctg
    38881 agaacagata gataatagcc ctggcctttc ctctagatcc ttgtttttcg aatgactgtc
    38941 atccatttgt tctcatctcc tttactaagt aattttaatt catgacttcc aatcattttt
    39001 cgaatagtta tttttccaat tagaccacct cctttttatt tttcaccgat ggggatttgc
    39061 ggcaacaaaa aaacctctcg ccaaatactc agcgaaaggt ttgaaaaagc atattaaaaa
    39121 aagcttctca gatctcatcg ttgagttttg acactgtaca acgtaaaaag cagatacctg
    39181 cttttagcta ccttatgaaa agccttatct cgacaattcc tgttctaccc attggcgtct
    39241 ctcgacgttt ttgggcagta gcctatgttt gtataggagc ctcacctaac aaatcttatt
    39301 cggttttcct tcgttaatat aacaactaaa aaagaggatg tcaaatcaat tttccatgtt
    39361 tttcatactt tttttaaaat acacacgtta tattcctgtc tcacgcggtt ttatttgtct
    39421 cattttccac ctcccgctat aatagaaata tagtaggaaa cgaggtgctg ttatggaaag
    39481 aacacttgtt attatcaagc cagacggcgt gagacgccat ttagtcggaa gcatcatcca
    39541 acgttttgaa gcaaagggac tggccattgc tgaaatgaag tttgaaacta tgactcctga
    39601 attagcaaaa gaacattatc agcacttgac tgagcgcagt ttttttgatg aactgatcga
    39661 ttacatgact tccggtcctg tcgtttatct tgtgctggtc ggcgaggaag tgatcgatat
    39721 cgtccgtaag atggttggag caacaaaagc tgccgatgct gttccaggta cgatccgagg
    39781 agactacgcg ctgccgggga ctgaaaacat cattcacgct tctgattccc gtgatgctgc
    39841 ggtaaaagag atcgcccgct ttttcccgcc attcgatata aacaaaccgt ctgaaaaagc
    39901 ggcgaagtga tacaaattct aaactgctgg tctagttgct gggttcagca atggccagca
    39961 gttttttctc taaggacctc cgttgattct ttcctaacat atattcgagc actgtgaaga
    40021 attcttggta gtctttcgtc ttttcttccc ctaaagcagc agaaatcaat ctttgataat
    40081 aatctgccat caatgtttca tagatcactg tacttctttc tttatgtgat aagctccgtt
    40141 tcatatcttc attcacacta cgtgcctttt tcaaccgacc attttctata taaaacgaag
    40201 tcaggttcat taaaaaagta aagagatact gctcatgatt gttcaactgt gctaatcgtc
    40261 gcattctttt tttgattttc aaataattgt tctcaatgaa ccgatcactg aatatccaag
    40321 gaaaatcagc tagaatagat agttcaaatt gaccatagtc tggtatctgc atcaagtatt
    40381 cttcaatgat tcggcattca taacgtaaaa attcaaattc tgtctcagat acttctgttt
    40441 tttcgaccat gtgaagattc aaaaccaaat aatacagatc ttctgttttc ttaaaatgcc
    40501 tacggttatt gctgatctct ttataaggat caaagctgtc ttcttgtacc cgatctagca
    40561 ttcgtctttt tttctttaac tttattggtt catccagctg gtttcgcatc cattcatatt
    40621 ctgcaagtgt catgttcatt cgctctaaaa atgatctcaa tgttacaaat gacatttttt
    40681 tcactgaatt tgtctcaatc ccgactagag aagtcttaaa acagattcct tccgctaatt
    40741 gggactgtgt caacttcttg ttgactcgaa gtttcttgat caattcacca tcatacataa
    40801 tagttctcct ttttaattta aatttttcca cattcaataa atagatacgt taaaaaggaa
    40861 aaatacacga aaaaaataaa aaaatgtttt tttcataaaa aataccaacc ttcaagcatt
    40921 agaatgttgt ctaactactg aaggttggtt tgattgttta ttgattattt ttttgctgtt
    40981 caacgtctgt tcttgttact ggatataagt tggttgttgt tttattacca ttttttgaaa
    41041 agacacttgt cgaatgttcg cctttttgct tttcgattgc ttcattacgt tccgcttcat
    41101 ttttatagtc atattttttc ggatcaatcg tctcaaatcc gtttggcaca taaaaccgca
    41161 agagattttc ctgattcagc ttatctgaaa gacttaacgc agtcttgact ttttcctgat
    41221 ctttggagat ttcctcatcg attcctgctg ctttcgtatc gatgatttct cctgtctgat
    41281 tattgtaagc ttttcctcct aggacggtgt atttgggtgt cacaaagttc ccatttcgaa
    41341 aagcaactac ttgatcatgc tgagaagata ataagtctgt accaaaatga agataatctt
    41401 tatcatcgat tcccaataga tgtagtaatg tcggcaaaac atcgatttct ccaccgtatt
    41461 catgattgac tgtcccttta gtataaccag gcatatggat catcaatggc actcgttgca
    41521 tctgtgcgtt gtcaaattca tcccatgtat ctggatcttt accaagagcg cttgctaaat
    41581 ctttattatc tgtattcgag atcccaaaat gatccccgta aatcacaaag attgaatttt
    41641 ggtaaatacc agattttttc aaatacgtaa aaaattgttc caatgattga tccagataat
    41701 gtgccgttcg aacataatta tctactgtgc tattgccagt attcaaagat ggaaagtcga
    41761 aattcttgtc atccgtataa taaggcgtgt ggttggttac ggaaagaaat ttcgtgtaaa
    41821 acggctgttg tagatgctca agatattggg cagattctct gaataaatct ttatctaata
    41881 tcccataacc taacgtttcg tcggattcat caaaataaga tcgatcaaag aaattgtcat
    41941 aacctaagtt tttatataca tgatctctat tccaaaaact agctacattc ccatggaaaa
    42001 cagcgcttgt atagccttgc ttttgtccaa ggatcgctgg tgcggcttga aagacattgt
    42061 ctgacccaag ttctgtgaat aatgagcctt gaggtaaacc aaatgtgcca gtttccaaca
    42121 tattttcagc atcacttgtc tttccctgtc ctacttcatg aaagaaattg tcaaagctga
    42181 tcgttgcttg attctggaaa atactattta aaaacggtgt gacttcttgt ccgtctacct
    42241 tcatattaat caaaaactgc tggaaacttt ctaaatggag aacgatcaca tttttccctt
    42301 tagcgatccc aaatgtttcg ggatttggct ctgcataatg tttctttgta taatctaaaa
    42361 cttcatcaat cccattactg cttgcatgcg cgcgaacact gctagtcatt cctgttttga
    42421 ttccgtcata aatagtatac gcatcgattc ctagatattt gacaatatat gaacggtcaa
    42481 atgttcgctg cagcaattgt ggacggttgg cttcgctcag cgctagattt cctgaaaaaa
    42541 taagccctga aagacaggta acagcgatag ccatcggttt gccgacaggg ttgcttttga
    42601 taggtatttt cttgaccttc aaccaaacca gtagcccaat gaacacagcg atatccagcc
    42661 agtagatgac atcatggggc ttcatcaaag aaaaggagct tcctgacaat ccttgcgaca
    42721 ctttcgaaaa gcctaataca gatttgactg taatgaaatc tgtgaattcc cgataaaaaa
    42781 taatattcaa gtacaacaaa agcgtattta aaatatcaat gatcaaaaga atagctaacg
    42841 ctggctttgg ctttttaata tacaaagaaa ggccaaaaaa caataaggta gtcgcaattg
    42901 ggttgatcca caagataaag tactggatcg taccttccac acctaatgaa aaatctgcat
    42961 agtaggcaat gatcgtcttc agccagaaaa agaaaacagc tgtcaaaacg attgctaaac
    43021 gattttggca caatttttta agttgtgtca cgtatatcac ttctctctat tcacattttt
    43081 tcttattttg ctcctgaaaa atgaaaattt cctaaaaaag ttgttatctt aagatttttt
    43141 tattctttct aaagattatt ccgtccactt ttcacagcat aaaaccgctg cgatgtaagc
    43201 gattaaacta atgaagagat aaaagtcttg tggtgaccgc ttcactccac ggtattcaaa
    43261 agccagtttc tcggtattcg tacaaaaaaa gaggctgtga caaaattctt gtcgcagctc
    43321 cttatttctt gatgcaggac agctttttca caacttcttc cttaaacggt gttctcctgc
    43381 caactcctcg gccacaagtc acaatattta taaaacatga gaagctgttt tttgaaattg
    43441 ttccttgtgg ctcagagtta aacggcaggc tcaagacctc ttgatacacg gtgttcaatc
    43501 agctgaccct cggtattaga ttatgtcagg acgctaattt tacaacctct tggtaaacgg
    43561 tgttcaaaag cttgcatctg cggtaataag cccaaccaaa cgaaaaatat aaggagctat
    43621 tttttgaaat tgctccttgt ggctcagagt taaacggcag gctcaagacc tcttgata
//
LOCUS       DAFENC010000022        42995 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.022, whole genome shotgun sequence.
ACCESSION   DAFENC010000022
VERSION     DAFENC010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42995
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.022"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            214..498
                     /locus_tag="LP493_001509"
     CDS             214..498
                     /locus_tag="LP493_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HBL2133666.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(779..1198)
                     /locus_tag="LP493_001510"
     CDS             complement(779..1198)
                     /locus_tag="LP493_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HBL2133667.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(1200..1784)
                     /locus_tag="LP493_001511"
     CDS             complement(1200..1784)
                     /locus_tag="LP493_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HBL2133668.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(1831..3306)
                     /locus_tag="LP493_001512"
     CDS             complement(1831..3306)
                     /locus_tag="LP493_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HBL2133669.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            3487..3798
                     /locus_tag="LP493_001513"
     CDS             3487..3798
                     /locus_tag="LP493_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133670.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(3913..6249)
                     /locus_tag="LP493_001514"
     CDS             complement(3913..6249)
                     /locus_tag="LP493_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2133671.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            6391..7059
                     /locus_tag="LP493_001515"
     CDS             6391..7059
                     /locus_tag="LP493_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2133672.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERVGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            7062..8105
                     /locus_tag="LP493_001516"
     CDS             7062..8105
                     /locus_tag="LP493_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL2133673.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(8342..9223)
                     /locus_tag="LP493_001517"
     CDS             complement(8342..9223)
                     /locus_tag="LP493_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL2133674.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            9382..10110
                     /locus_tag="LP493_001518"
     CDS             9382..10110
                     /locus_tag="LP493_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HBL2133675.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            10266..10583
                     /locus_tag="LP493_001519"
     CDS             10266..10583
                     /locus_tag="LP493_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBL2133676.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            10576..11184
                     /locus_tag="LP493_001520"
     CDS             10576..11184
                     /locus_tag="LP493_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HBL2133677.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            11239..12030
                     /locus_tag="LP493_001521"
     CDS             11239..12030
                     /locus_tag="LP493_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HBL2133678.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            12168..12656
                     /locus_tag="LP493_001522"
     CDS             12168..12656
                     /locus_tag="LP493_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBL2133679.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            12707..13579
                     /locus_tag="LP493_001523"
     CDS             12707..13579
                     /locus_tag="LP493_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBL2133680.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            13755..14117
                     /locus_tag="LP493_001524"
     CDS             13755..14117
                     /locus_tag="LP493_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBL2133681.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            14126..14878
                     /locus_tag="LP493_001525"
     CDS             14126..14878
                     /locus_tag="LP493_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2133682.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            14892..16694
                     /locus_tag="LP493_001526"
     CDS             14892..16694
                     /locus_tag="LP493_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2133683.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            16971..18011
                     /locus_tag="LP493_001527"
     CDS             16971..18011
                     /locus_tag="LP493_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBL2133684.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(18063..20207)
                     /locus_tag="LP493_001528"
     CDS             complement(18063..20207)
                     /locus_tag="LP493_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBL2133685.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(20564..21937)
                     /locus_tag="LP493_001529"
     CDS             complement(20564..21937)
                     /locus_tag="LP493_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL2133686.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(21937..22332)
                     /gene="rbsD"
                     /locus_tag="LP493_001530"
     CDS             complement(21937..22332)
                     /gene="rbsD"
                     /locus_tag="LP493_001530"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HBL2133687.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(22360..23277)
                     /gene="rbsK"
                     /locus_tag="LP493_001531"
     CDS             complement(22360..23277)
                     /gene="rbsK"
                     /locus_tag="LP493_001531"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBL2133688.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(23385..24398)
                     /locus_tag="LP493_001532"
     CDS             complement(23385..24398)
                     /locus_tag="LP493_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBL2133689.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(24479..25078)
                     /locus_tag="LP493_001533"
     CDS             complement(24479..25078)
                     /locus_tag="LP493_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBL2133690.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            25264..25965
                     /locus_tag="LP493_001534"
     CDS             25264..25965
                     /locus_tag="LP493_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2133691.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            25975..28686
                     /locus_tag="LP493_001535"
     CDS             25975..28686
                     /locus_tag="LP493_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2133692.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            29137..30765
                     /gene="treC"
                     /locus_tag="LP493_001536"
     CDS             29137..30765
                     /gene="treC"
                     /locus_tag="LP493_001536"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HBL2133693.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(30825..32006)
                     /locus_tag="LP493_001537"
     CDS             complement(30825..32006)
                     /locus_tag="LP493_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL2133694.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            32258..33781
                     /locus_tag="LP493_001538"
     CDS             32258..33781
                     /locus_tag="LP493_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HBL2133695.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(33850..34578)
                     /locus_tag="LP493_001539"
     CDS             complement(33850..34578)
                     /locus_tag="LP493_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2133696.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(34591..35871)
                     /locus_tag="LP493_001540"
     CDS             complement(34591..35871)
                     /locus_tag="LP493_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBL2133697.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(36012..36614)
                     /locus_tag="LP493_001541"
     CDS             complement(36012..36614)
                     /locus_tag="LP493_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBL2133698.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            36859..37065
                     /locus_tag="LP493_001542"
     CDS             36859..37065
                     /locus_tag="LP493_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133699.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            37377..38096
                     /locus_tag="LP493_001543"
     CDS             37377..38096
                     /locus_tag="LP493_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBL2133700.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(38177..38860)
                     /locus_tag="LP493_001544"
     CDS             complement(38177..38860)
                     /locus_tag="LP493_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HBL2133701.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            39078..41264
                     /locus_tag="LP493_001545"
     CDS             39078..41264
                     /locus_tag="LP493_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBL2133702.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            41610..42020
                     /gene="spx"
                     /locus_tag="LP493_001546"
     CDS             41610..42020
                     /gene="spx"
                     /locus_tag="LP493_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBL2133703.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            42034..42390
                     /locus_tag="LP493_001547"
     CDS             42034..42390
                     /locus_tag="LP493_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HBL2133704.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT        14022 a         7563 c         8595 g        12815 t
ORIGIN      
        1 aggaagaggt tgtgagcctg ccgtttaact ctgagtcaca aggagcaatt tcaaaaaaca
       61 gcttctcatg tttgttgact attgtgactt gtgaccgagg agttggcagg agaacaccgt
      121 ttattcgaaa aaaggaactg cgacaagact tttgtcacag ttccttcttt tttttgctat
      181 gctatactag atgtaaaaaa taggagaaat aaaatgaggg aaatttattc ttttgaatca
      241 aaaatctatg cttccgaagt cggcaagggc ggggcatata ttatttttcc gtatgatata
      301 agaaaagaat tcggtgctgg aagagttaaa gtccaagcaa cttttgacaa tgtgccgtat
      361 gaaggcagta tcgtgaatat gggcgtgaaa aatccagatg gttcagtctg ctacatcctt
      421 ggactacgaa aagatattcg taaaaacatc ggaaaagaaa tcggtgatat tgtagcagtt
      481 acagtgaagc aaaaataaaa gaggttgtga caaaagacgt gtcacaacct cttgataaac
      541 ggtgttcaaa agccagtttc tcggtagtaa gtcaaattta tgcaaaaatg tggaaaccca
      601 tgtttacaaa atttttctta ctactcgaaa cgaagcggct ttatcacaac ctcttgataa
      661 acggcgttca atcagctgtc cctcggtatt agctcaaaaa cggcaaaata tgagaagcta
      721 tttttccatt tttttctctc atactcaggt cataacgctg atttcacaac ctcttctttc
      781 ataatggttt ttcaccatct ttataataaa ctggttcttt gatatggaaa tctatttttt
      841 ccaaccaatc taaaatcttg taacctaact cttctgacat cggaaaagag gcgttgattt
      901 gtgcattgga gatatggtca acatggatac cggaagtgat cgtacaactt cccggaacgg
      961 cagttttgat gatcacagct attttttcgg ctaagacatc gtctttatgg aaccgaccat
     1021 cgtggctagg gaaacgtaca gtttgcatct ctgtatcacg agaaaatgta gtgactgttc
     1081 cgatatgtgg tgtatctccg cctgttaaag tgatcaataa gtctttaccg attactttaa
     1141 cagcagcttg gatcgtgaaa cctagtttgg ttacttcaac tatcgtttct ttttccatat
     1201 taatcaccct gccaacgttt tgaatgctca tttacaattt caaattgatc caaaagtttc
     1261 attgtatggt gattaacaag atcttggatc gtttgaggct gattataaaa agcaggaatt
     1321 ggtggtatga tttgcacacc tagtcgtgct aatttagtca agttttccaa gtgaatggca
     1381 tttaatggcg tttcacgagg aacaatgact aactttcgtt gctccttcat tgttacatca
     1441 gcagcacgtg caatcaggtt gtcgcctaaa ccaacagaga tacctgcgac tgttttcata
     1501 cttgccggta cgatgatcat tccatcggtc aaaaatgatc cgctggcgac agcagcacct
     1561 aaatctttgt ttgaataatg gtaatcaaac aggctttcga attcagttag tgataagtcg
     1621 gattccagct ttaagttctg ttttgcccat ggactgatga ttccgtgtgt ttctatcatc
     1681 ggatattctt ttagtttctt cactaggttg atggcataaa tggtgcctga agcgccactt
     1741 acaccaatca cgattttttt cttccgttgt gccaattgtt ccattttccg cactcctttt
     1801 tatgatgtca aaacagttgc agatcattca ttatttcaaa tatttttccc aatcttctac
     1861 ttcttggaat tttgcacgta caaaatgttc tttcatatcg aaaggaactg taccgtcaaa
     1921 gatagttttt gcacttatcc cacggaaacg aatagagcca ggattatatt ctggtaattc
     1981 tgatgggtcc aatggatggt tcctcattcc tgggatcacg atgatatctt tatctccttg
     2041 gaaacgagtg ttgaaagtcc aaactacatc gttcatgtcg aaaatatcaa catcttcatc
     2101 gactaaaatg actgtcttca attctttgaa ggctgataaa gcaagaatag ctgcttgacg
     2161 ctgaatacct tcatccgctt cgttttcttt acggatttgc atgatggtca tcaatttacc
     2221 accacctgca ggaggattgt agacatttac tacttttcct ggaatagctt tatcgaccaa
     2281 ggcaagaata cttgcttctg taggaatacc ggccatagat acgtgttctt cactgggacc
     2341 aatcgttgtt tgcatgattg gattgtcttt tcggtgagta actgctttga ctttcactac
     2401 ttgtacagct ggattagcat ccccagtata gccaggaaat tctggcattg cttttcctga
     2461 gttcgtgttg atatcttctt gcattgtttc atttggcatg atttctgctt caatgatgaa
     2521 ttcagcacga gcaataccca cttcatcgac tgctatacca tcaacgattt gaataggttc
     2581 gttacgcaaa gctcctgcac accatagttc attgtagcca agtggagtgg taggtggttc
     2641 gaaagtcgtg ccaatggcaa ttgctggatc taaaccaata ttgatagtga taggcattgg
     2701 tttattcaag gcttcgaatt gtttttggaa gtgaccaatg tggcgtccgc caggcatgat
     2761 gtacataccg atcgtatctt tatcttctag aaccatacga tggatcgtta catcgctcat
     2821 tgttttttct ggatctgatc ctaagactac acccattgtg atgtatggac cagcatcttc
     2881 aggagtattt gtaggtgcag gcaaaatgtt gcgaatatcg aagtctgcat cggtagctag
     2941 atgaacgact tcttgtgctg gagcgtctgc tttgtctact ttcacaggtt tgattggatt
     3001 ttctacagcg tctttcaaga aacgaccaag tgttcgataa tcatggtgca aaatttcacc
     3061 tacacgttta cgactagcca ttgttccgat gttcacacgt gtgccgggga aacctttgat
     3121 attgttgaaa gtcatagctg gtccttcttg agtcggacgt tttactgtac cgccagcacc
     3181 gatataacgg taaacaccag ataattctgc ttcaggatcg atttcaatat ctgtttcgtg
     3241 atattgacct ggaagtgttt ttagttcttc gatgactttt cttaaatcat acggttgatc
     3301 tgtcatgaga gattcctcct tagttgtctt tacctatcta tagtaaaagg tgaaaaagag
     3361 gaaaacaatt caacttgttc ggtaaagtat tctacaatgg aatggatgcg tttttttgat
     3421 aatagaataa actatgatat acttatcact aaaagaaagc gcatacttag tgttggagga
     3481 aggaaagtga aaaaaatgga ggagtcattt cctaaagcag taaaagtgga aaatatagcg
     3541 aatattttga aagttacatt tgaaaacgga gaagtaaaat acgtgaaatc tcattggaca
     3601 gaagagataa ccgatgcctt gcaatttgga aaaaaaggaa gaggaaaaag aaaaaatctt
     3661 ctcgcacttt ctcgtaatat gtggattggg actgaagtaa cgattgaagc agatggaaca
     3721 gtattcataa atggaaaaga caggtatacg ccagaagagt tgtggtacaa aggaaagaaa
     3781 agtataccag aattataaaa aataattaaa aaaaacagcg cgaaacaagg aacatattac
     3841 ttcctcgttt cttgctgttt tctactattt cagcgctctt atgactcaaa tctaaatgtg
     3901 gttgtcacaa ccttattctg cacgcaaagc gatagcggcg tcttttttcg ctgccattcg
     3961 tgcaggaaga tgaccgccaa gcatcgtcaa tatagtagag acgatcacta gaataatcgc
     4021 atggacagga tttagttgag caacattttt tagatccgtc atgttgtata agatgctatt
     4081 gatagggaac gtagctagcc atgcaataaa cacacctaat atcccagaag aaatacctaa
     4141 aatacacgtt tctgcgtcaa atacgcgagt gatgtctttt ttacgtgcac ctaaagcttt
     4201 tagtacaccg atttcttttg tccgttcaat cacagatgta taagtaatga tactgatcat
     4261 gatcatactt gttactaaag agatccctgc aaaagcaata aggacataag tgatagcatc
     4321 catcaatccg ccagtcagtt cagtcatcgt tccagctaaa tcagtataaa tgattttatc
     4381 ttcatctgat ttgcctttat tgtaatcatc tagataatcc aagatctttt ctttgtcttc
     4441 aaaattgttc ggataaatca tgatacttga aggcaagctg tctccaccta aataactaag
     4501 caatgtttgt ttggcatttt cgtcaacttt ttcagtagtt aagacattta caccactgtc
     4561 tctttgagct ttgacgattt ctgattcttt gttttcgttg acgatttgag tcgttaattg
     4621 atcgctataa gcgattcctg gagataagag attcattgta gaagaagatt tcacgcgtag
     4681 gatccccgag atcttcaatt catcagaagc attctgatac atcgcatcat aatctgtatt
     4741 agggataaaa ttcccagttg gaagttttgt atagtaagta ttgttgttta ctaatttgaa
     4801 tgttgtacca acgatatcat caaaatcaag tttttcgtct tctttcacat caaatccaag
     4861 attcttcaat gcgttgatat tagtattatt attgccgtct acgatcagca cgacatctgt
     4921 tgctgaggct ggataacttc cggcaagtaa agaataattg tcttttaaaa agttttcttt
     4981 gctagtgtca agctgtgtag ggaaacttga cactcccaca cctgtcattg ctgacatcgt
     5041 actagataaa gaaagagatt ccgtatcagg attttgattc gagaagctga caggctgtac
     5101 tttgccattt acatcacgta aaagattgat tcctgtagta cgggtaaatc cgatattatt
     5161 acttaagtta ggatcgatgt ctgttacgta atcgacgtat gtttgatcaa tcttattcgt
     5221 gtgctgtgct ttatcttctt cgctgacttt tgcagtaatc gttttgctgt ctggataatc
     5281 cgctttgctt gcacccaatc cggcatcgtc acgagtctgg ttagtcgtta ccttagaaat
     5341 agtaatcgga aatttcgcca tcgtttcagc ttgcgtgtta tcgatttgtt tttggaatcc
     5401 agaagaaagg gacagaacga tcgcgattcc gatgatccca atactggaag caaaggaggt
     5461 caagaaagta cgtccttttt ttgttcggat attgttgaag gaaagcttta acgctgtcca
     5521 aaaactcatc tttgttctgc gtaagttaaa ttgatcatct tttggtcgtt cgatgtgagg
     5581 atgggaatct gttaagatct taccatcaga aaattcaatg attcgatctg cgtattgatg
     5641 ggccagttca ggattatgtg tgaccatgat cactaatttt tctttcgata actcttggat
     5701 caattccatg atctggatac ttgtttctgt atctaacgct ccggttggtt catcgcacaa
     5761 aaggatatct gggtcattgg ctagtgctcg agcgatggcc actcgctgca tttgtccacc
     5821 agataactga tttggctttt tatgcatatg atttgtcaag ccgactcggt gcaatgcatc
     5881 ttctgcccgt tttcgttttt cgtctttaga aacaccactt aatgtcatcc caagttcaac
     5941 gttttcaata atgcctagat gaccaatcaa gttgtaactt tgaaaaatga aaccgataga
     6001 gttgtttcgg taggcatccc agtcactgtc cttaaagtct ttagtagact ttccgttgat
     6061 taccatatca ccggaatcat aattatctag tccaccaatc acattcagca tagtcgtttt
     6121 accagaacca ctaggaccta aaatcgctac gaattctttt tgtctgaaag cgacagacac
     6181 accatccaat gctttggtgg tggtttcgcc gactttataa tattttttta tatcttttaa
     6241 ttgaagcata atcacccttc tcccgtattg aaatattcgg tatactaata agtatatcag
     6301 aacaatgatc gtagtatacg aaataaatgt taactgaaga tgaactacaa gaaaaaatct
     6361 agaaattttt caaaaaacag agggagatca atgaatcgta ttttagtagt agaagatgat
     6421 ccgcaattac agttgcttta ccgttctgtg ttggaacgag tgggcttttc agtcatcacc
     6481 gcattgaatg gagaggatgc gctgaaaaaa ctagaagcga cacgtataga attaatcatt
     6541 acagatatca tgatgccgaa aatggatggc tatgacttgc tagactcatt acgtagcacc
     6601 agatttgaca cacctgttct aatgattacg gcaaaggccg attttgagga taagaaacgc
     6661 gggttcaaat taggagcaga tgattatatg acaaaaccca tcgatgtcaa tgagatgatc
     6721 ctacgtgtgg aagcattgct tcgacgttca aagatcaatt acagcagtag cttgataatc
     6781 ggacaaacaa aattagagct agatgcttat acagtgttac aagatcagca ttcgttgatt
     6841 ctgcctcaaa aagaatttct gcttctgtat aaattactgt cttatcccaa caagatcttc
     6901 actcgccaac agttgatgga tgatatttgg ggattagata cgaatacaga agaacgaacg
     6961 atcgatgtac atatcaaacg tttaaggacc cgttttgaaa agacggaaga ttttcaaatc
     7021 atcacagtac ggggactagg ctataaggcg gttatttaaa gatgaaaaaa aagctatttt
     7081 cacaattatg gatctatttt gctagtattg tcttcatttc gatcttagtg acactgctgt
     7141 gttttctcgg ttttattttc ttattgtctc gacattctat ctcgcctgct gaatcggctg
     7201 gaaaaccaac gttatacccg ttattcgtct ttgcggggtt cagtatggtc gtgggtacag
     7261 gaatatcgat ttttgttggg cggcgtatcc tgcatccaat cagtgcgcta gggacaaata
     7321 tgagtctggt agcaacggga gatttttcga ttcgaatgga tgaacagcag aaagtagcag
     7381 aagtacagca actgtataaa gatttcaacg ttatggtcca agaactcaat agtatcgaga
     7441 cactgaggaa tgactttgtg tccagtgtat cccatgaatt caaaacacca ctagcaacaa
     7501 tccaaggata tgttcaattg ttacaagccc caaatctctc tgacgaagaa cgccaaatat
     7561 ttttatatcg gattatcgaa agtatcacgc agctttcaca attaacagag aacatcttaa
     7621 aattgaacaa actggaaaac cagcgtatcc aactggaaaa gaaagagtat cgattagatg
     7681 aacaaatcag agaagtaatc gttttttttc agcctaaatg ggagaaagaa cagctagaat
     7741 tggatatcga acttgctgca gtaaattaca caggcaatga agagtttttg taccaagtgt
     7801 ggctgaatat catggataac gccataaagt acaatcaaat caatggacag attcatatca
     7861 aactatttga gacagccaca gagattgtac tggaagtgac cgattcaggt gtaggaatga
     7921 atgaagagac cagagatcga atgtttgaaa aattttatca aggagataca agtcgtcaaa
     7981 tttctgggaa tgggctagga ctttcactgg ttaaaaaaat tctagaactg catgatggac
     8041 gtattgatta tagcagtatc gaaggagtag gaacgacagc aatgatacgg ttaagtaaac
     8101 aataggaaaa agaataaaac ccctaaaaat tctattgaag gtttttaggg gtttttagtc
     8161 gtttttttgt gattagggaa atgttcttac ggttcttttg gcataaaaat cgctgctttc
     8221 ttattgaact acgagaaatg ttagaggtgt cattgaaaca aggacatgat gcaagaaaga
     8281 gagcgaaagt catgcgtcgc tctctttttt tgggtggata gatggacaga aaatgtaggg
     8341 cttagttttc ttcttgattt aaatactccc aaaatgtatc tgaagccaaa gaatgctcac
     8401 cgactttacg agtaaatgca agataactct ctgttgttgg agaaataggg agaatcacag
     8461 tattttcttt taatagattc ttgactgttt tttccataac aatagcaatc cccatgtcat
     8521 ttgcaatcat attgatgatc aagtcgattc ttgctccttt ataagagatt tttggttcaa
     8581 atccagcttc gcgacacaga tctagtacag gttgatacaa gttcgtagtg gggccaagga
     8641 gcaaaaagtt ctcctttttc agttcgctta gatccaattt ctttttacta gctaaaggat
     8701 gatttttagg tagaactgct acaaaatcgt ctgtttcagt aggcaaccac tcaatcgaac
     8761 ttggtggggc ctggaaactt ctagcaaagt ggatcgtgtc actatgttca ttggcgtcat
     8821 tgtaagttaa ttcgacactt tccacttctt tcaactggac tgtaaattca ggatggcgtt
     8881 tcaaaaactc ggtgattttg gaaaaacctt tataattgat cattgtcggt atcgttaaga
     8941 tatttaatga aagattgttg tctttcgtat aggtttcaag cacttcttgc atagcatggt
     9001 attgttctac gacatttttt acatatggga gcaataagct tccagcttcg gtcaattcga
     9061 tttttctatg ggcgcgttcg aataatttga cgtctaattc tgtttctaac gaaagaatct
     9121 gtttagaaat atttccttgg gtggtgaatt gtcgatcagc agttttggtg aaattcattg
     9181 tttcggctaa atcaagaaaa acttcgaatt tatggatatc catcatattc ctcctactta
     9241 ttccaataaa gaatacttta acacaaaaaa tgaattggtg taatcttctc tgtctgttac
     9301 aatctttctt gcagcgaaag caataattac agaaattttt ctgatttttt tcgcttcgta
     9361 gaaaaagaga ggagtttttt gatgccaact ggagttttga tcaatgtagg ttccgttttg
     9421 tttggcggac taattggcgg attagtagga aataaattaa gtgaacattt taaagcacag
     9481 ctgacgatgg tttttggtgt gtgttcgatg gggatgggaa tctattccat tgcgccgatg
     9541 aaaaatatgc cggctgttat ttttgcttta gtgataggaa cagcgattgg tttgattgtt
     9601 catttaggta atgggataaa taagggggct gcgctgatgc aagtacctat ttctaaaatc
     9661 ttccctagtg aaaagcttgg tatgacccac gatgaattta tcagcacatt agtgacggtc
     9721 attgttctat tttgtgcaag tggtacgggg atctatggaa gtttagattc tgggatgaca
     9781 ggagacagta cgattttgat ttctaaatct gtccttgatt ttttcacagc agctattttt
     9841 gcgtgtaatt tagggtatgt cgtttctgtg atagcaattc cccaattcat tattttttat
     9901 attttgttct tattggcaaa atttatttat ccattgacta caccagacat gatcttagat
     9961 tttaaagctt gcggcggatt cttgatggtc gctaccggtt ttagaatgat caacgtgaaa
    10021 atgttcccag tagctgacat gatacctgca atgatcgtta tcatgccact gagctggatg
    10081 tggacaaatt ggattatgcc actgttataa taaaaatcaa agagaagcca ttttttgctg
    10141 actaaaaagg atcaaatctt ttagtcagtt tttttgtatt tgacaaactg attttgaaac
    10201 tatattatat gttgtataat atagattgaa ataaaatatt acacttgaga atagaaggtg
    10261 acgtaatgca catccagatt ccaactgttc ttcttgatgg tactgtgcta gcagcattaa
    10321 gcaaggaaga tatgtatggg tatgccttaa caaaaatcgt acaagaaagt ctctctgtca
    10381 gtgaatctac actatatccg gttttgagaa gattgaaaaa agaaggatat cttgagacct
    10441 atgatgaacc ttttgaaggc agaaaccgtc gatattactc gttgacacca atgggaagtc
    10501 gtcatttaga agaaattatt gatgaatgga ttgtttttcg agattcttta gaccggttat
    10561 tggaggagag cacaaatgaa tgaatatttg aatgaagttg tggatcatct tcaagaaatt
    10621 cctgaagacg atcgttttga tttgatccag tattatgagg aatatttttt agattctgga
    10681 aaaacattag atcagatcat tgatgaatat ggtacaccaa agcagtttgc cttaaaatta
    10741 aaaatcagtt acttttcaga agaagaacaa gcagaaaacg agttagtgaa aaatccaaaa
    10801 agacaaattc gcctgatttg gttaatcatt atcggtttat ttgcttctcc tgtcctcatt
    10861 ccactagcac tggggtttat attggttatt gggggactat tggttgcttt actagcgctc
    10921 atttttagta tctatgtttt atgtatcagt atcttaggtg ttggcctatt catgatcatc
    10981 tcaggaatca gtgtgtttgg acaatcgatt ctgagtggat tattctttat cggtgtcggt
    11041 ctgttcgcca caggaagcgc agtatttatt tcgccactgt tgctgaaagg aacaaaaggg
    11101 cttttttatg tcatgatgaa ctttgttaaa tggatgggac gacgttttat tacaaaaaga
    11161 gatctgcatt cagcgggcgt ttgaaggagg acacataaat tgagattgaa acattttttg
    11221 attaccggta ttggtctgat gcttactggt ggcctcctag caggtgcaac ttatacatta
    11281 ggcgctcaaa agagtctgac ttgggataat ggtcctcggt tgatcgatat ggttactgag
    11341 acaaaaaaaa tcaaggatgc aaacaaaatc gtcatccatg cagaaaatca aacagtttcg
    11401 gtcatacgcg gattggattt tgagataaaa acgacttatg ataagacaga aaagccagaa
    11461 ataaaggaga aaaatggcgt gttgactgtg aatgcagtca aaaaatcaac aggtgcaatc
    11521 attagtttag aagacacaag tgcacaaatc actattgttg tccctgcaga tcatgaatta
    11581 tctgaattga caatcgaagg gaataatagt gcaattgata tcaacgaagt atcaatcaaa
    11641 aaagtgaata ctaagacaca tgatggctgg gtatcgttca atgaatttac aggaggaaca
    11701 ataactgcga aagatgaatt aggctcactt cgattagatg aggccaatgt ggataacttg
    11761 atcgtcacag gtgaaaacag caacttccat ctagaagaca gtttgatcag caaagaagga
    11821 aaagtcatcc taaacggtgg caatttatct ttgcatgaga tggaaaacag tggctatact
    11881 atccaaacgt ctggtgaatc ttatattgaa aaagactacc agccaataac aaatactttg
    11941 ttagaacaag gacagaaaaa gctaaagatc actgctaaag acacatcgat caatattacg
    12001 acggatcaag aggacaatga aacagattga tcctgtactc aactggatat tttaagaaaa
    12061 aacagcaaag atccttccaa tctttgctgt ttttcatcgc ttaacgcaca taactatagt
    12121 aaaataagaa agaaaatatc taaaaagaaa acagggtgaa agagtatatg aaggtagaag
    12181 aaggtcaaag agaaaagtta aaaacagaaa tggaaagatt acatacttat atcactcaac
    12241 taagccaaac cttctatgat ccagacaaag aaaaagtgat ggttaattac ccgaacaatt
    12301 cagaaggtcg ccaattagag caagtgtacc atgaagtttt caaacattta ttgacggtga
    12361 agaaagagct ggattattat tctttaccga ttatcgatac aggaatattg aagtatgatg
    12421 ggaagaagga acgatttatc tttaaatctg ttcgggaaga tttgcctctt tcagcaggga
    12481 tggatctaga ggtcttggta gaagactatt ttacagaaga aaagcactgg gttcgaacaa
    12541 aattggatta tttaccgcag gcagccggag ggacacaggc aagcggttgg tacatcactg
    12601 aagacaaaga gttagaacta gaaggtgtaa tggcgcgtat tcgaaaaaaa aattaaaaaa
    12661 gtaacattag atatttattg aaggataaag gagcgcagga agtagcatga gagaaaaaag
    12721 agcattttat atcaatggtt atgcagggat tgtcggattg gtcgtattag ctttagttgg
    12781 attgtttttc ttctatttag gtatgtggca agcgaaagtt tgggcacttt ttttaagtat
    12841 ttttctttgg ttgatcacgt tattgttgtt aagttcggca actgtagtca gtcctaatca
    12901 agcaaaagta attttgtttt ttggacaata tttaggtacg attcgagaaa atggcttttt
    12961 ccttacgata cctttggcac aaaaaatgac tgtttcgttg aaagttcgga atttcaatag
    13021 ttctgtttta aaagtcaatg atttggatgg aaaccccatc gaaatctcag cagtagtagt
    13081 ctttaaagtc gttgatacag caaaggcatt attcgatgta gcgtattatc aagattttgt
    13141 agaaatccaa agtgagacag ccattcggca tatcgctagc caatacccgt atgatacatt
    13201 caatgagaat gatttgacgc ttcgaggaaa cacgacggca gtgtctgacg agttgcaaaa
    13261 agagctgcaa gagcgtttag cagtagcagg tgtcgaagta atcgaaacac gcttgaacca
    13321 tttagcctat gcaacagaaa tcgctagtgc catgctccaa cgtcaacaag caaaagccat
    13381 tttgtctgct cgacaaacca ttgttgaagg agctgtcaca atcactcaaa tggccttaga
    13441 gcaaatcgaa gatggacaag aaatcaattt caccgatgat cggaaagtcc aattgatcaa
    13501 taatttactt gtctcaatca ttacagacaa aggaacgcaa cctgttatca atacaggcga
    13561 catgaaagac cgtaagtgac atactttttg taagatagga agaaggagtt taggacggat
    13621 tattgtcttg aactcttttt ttagttgttt taaagaaaat gacaaaattg aaagaagaat
    13681 gatagttgat tcgaaggcag aattgttcgc ttttttctat aatcagtata taaagtaaga
    13741 gagaagggga aaaagtgaaa aaacttctga tcggtctact tgttttcatc gttgtggtac
    13801 ttgcaggggt gaaaatcgca gattacgtag ttatgggtgg agaagaatac tatgtacaaa
    13861 ttacgacaga tggtacaaaa acagtttcaa aatcagactc tggacaagaa acagtcaact
    13921 atagatatat cctgcctggc tatacgaaag agggtaagga aaaagaactg gacttcaagg
    13981 gacaattgac tcgaccgctt cgtaaaggag catatttaaa aatcacctgg aacaaaaata
    14041 aaggtgtcac ttcgtatgaa gaagtcgaaa aaaaagacgt gccgaaaaca gcactggaaa
    14101 aactaattaa agggtaggga aagaaatgaa caaaatagtc gaagtacaga atgtaacaaa
    14161 agtatacgga aaaaacaatg agaaaaagac gcaagcatta agcggcatca gcttcgatgt
    14221 agaaaaaggc gaatttattg ggatcatggg cgcttctggt tctggtaagt cgacactttt
    14281 gaatatttta tccacattag ataaaccaac agatgggcat atccgaatca atcaaaaaga
    14341 tgtgaccaca ttaaaaggaa atcaactagc agattttcgt gcgaatgaga ttggctttat
    14401 tttccaagat ttcaatttat tagaaagctt gacagcacaa gaaaatatcg ctgttcctct
    14461 ttctttacaa ggcgtcagac caaaagaaat caagcaacgt gtccaaaaaa ttgcagaacg
    14521 tttatccatc tctcatattt tggaaagcta tccttctgag atttccggtg gacaaaaaca
    14581 acgggtcgcc gccgcacgtg cattgatcac acaaccaacg attctattag gggatgagcc
    14641 tacaggtgcg ctggattcca aaagtgcccg ggatctttta gatacgatgg acgaattgaa
    14701 tacaaaagat catgtatcga ttcttcttgt gacgcatgat ccgttttctg caagttattg
    14761 ccaacgtatt ttattcatca aggatggcgg tatccatcaa gaagtgaaac gtggagatca
    14821 aagccgtgat tccttctatc gagaaatact atctattctt ggaaacttgg aacagtaggg
    14881 ggagattgac tatgctttgg aaattatcac ttactgggat caagagccgt ttaagagact
    14941 acttggtgtt attctcagga ttagttatgg catctgctat tttttacatg tttgaatcaa
    15001 tggcaagcaa cgaagctttt ttgaaaagta atacgatcgt tgcggctaca gttatcattt
    15061 tccgattcgg ttctgtttta ctagggatca tcacattcgt ttatatttta tatgcaaatt
    15121 cctttttgat gacgatgcgg caaaaagact atgcaatgtt tatgatgctg ggagcaaaag
    15181 gcagaaaaat cgcacagatg attttttctg aaacattctt agtagggatc gcagctactt
    15241 tagtgggttc agctgtcggt gtaggattga caagtatcgt ccaccgatta ttagtggatc
    15301 agttagatct caatatttcg cattttacac cttttagtat tcacgggttg ttgatcactg
    15361 ttttgttttt tgctgttttg tttttattag ctgctgttgt caatgctttt tcgattgtca
    15421 aaaaaccgat tttagcattg attcgtgcgg atcagacacc aacaagaatc aagcagcata
    15481 aattcttgtt tttccttgaa gtagtactgg gaattgcttt tctaggctgc ggttactata
    15541 tgatgaaaca cgtggggacc tatcaagtct ttggtatagg ggtagcctta gttacgatcg
    15601 tattaggaac ttatttcatt ttccattctg tgatcatttt ctttttatca ttactaaaga
    15661 aatcagaaca gatttcattg aaaaaattga acaatttcac attgtcacag ttaaactttc
    15721 gtattcgtga atatacacaa atgctctcaa tggtcgctat gctgtttgcc ttggcactgg
    15781 gcgctttgac ggtaggatta ggttttaaaa atgaaattgc agacttgaca gaaaacaatt
    15841 ctggatatga tctagtgatg aataatcctc gggcagaaga tcagcaaaaa atcaaagaac
    15901 tttcaccaac actttctgct tcttatactc aaaaagaaga tgcgggaacg atttactata
    15961 atgcaagtga atttgcggct caaccattga tcatgataaa acatgaagat ggaacaccgc
    16021 cgaagatcac gaaagaaaaa gttcctgcta aaaaaatgaa tgaactgact gtacaagagg
    16081 aacttcgaag ctatgaattg ccggaacagc aagaaaaaga aatcaaggta gtcagtcaat
    16141 cagaatttga tcaactgaac ttgccacaat ccactttaca gctagttcag gtaaaagact
    16201 tccaagcaaa cctgaaacca atcgaaacac ttgttgctca aaataaaatg aacaatccat
    16261 ctttgcaaaa agtagagtac agcaaccaga aatatgaaat gtatgaagtg tataatggtc
    16321 tattctctgg ttttgaattt atgggattct tcctaggttt agctttcttg accatgcttg
    16381 ctagctgttt gatgttcaag atcttgtcag gaagcaagag tgacattgct cgttatgaaa
    16441 tgcttgaaaa gataggaaca cgacgcgggt tgcttaaaca atcgatccgt agagaagtag
    16501 gcgtgttatt cttagcacca ggaatcttag gtgtagtcca tgtcttattc ggattacaaa
    16561 tgtttggtct attcatgcaa aatccataca aagatatttg ggttccgttt acgatattct
    16621 tcgtattgta tttcatctac tatgtactga cgacatggtt atatactgga atcgtattga
    16681 aaaagagatt gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa gcaaaaatag
    16741 ctcctcatat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt tgaacaccgt
    16801 ttgttcggaa aaagaggttg tgacaatatt tttgtcacaa cctttttttc acggtctttt
    16861 attagaatat agtaaatttt ttctcgttac tcacggaata agctgttaag aaaacggttt
    16921 ccatgtatac tggaatcagt gcaaatgaaa gaaaagaggg tgcaaggaac atggaaatca
    16981 atgaacaaaa ttttggcgaa aactatcact tgattacgat cacgaatcaa aatgggacat
    17041 ctttgtctgt cagtgatctt ggggcacggg ttgttcattt tcaaacaata atcgataatg
    17101 aaaaacgaga gttgatctta ggttttgatg aagcaaaaga atatctagaa aaagaccctt
    17161 atatcggtgc ttcaatcgga cgtatggctg gacggattac gaatggcaca ttcaaattag
    17221 atgatgaaac gttcgaagta aaaacagacc cggacactgg tcattgttta catggtggtg
    17281 cacctagctt tgaagccaag cagtggcatt atacagtcat caatggtgaa aacgaagcat
    17341 cggtcatttt ctatcagact agcccagata tggaaaacgg atttcctgga actttagatg
    17401 tagaagtacg gtatacgctg acgaacgatg atacatggcg agtgacggtc caagggatca
    17461 gtgaccgcaa aacagtattc aatcctacaa atcatgtcta tttcaattta accggtgatc
    17521 cagcacagtc aatcgacgaa catatacttt ggttgaatag ccgattattt gctacgctca
    17581 ataaagatac aacgcctaca ggagaagtag tttcagtaag tggcacagca tttgacttcc
    17641 aacgtcctaa aaaattaggt gaggtctttg ccagtgattt tcgccaatca atgatagtgg
    17701 gcggcatcga tcatccattt ttgttgaaaa aacaatctgg tttactaaat gctgcggaat
    17761 tgacaagccc agatgaaaaa gtatcgatcc aagtaaaaac agatgcttca ggaatcgtga
    17821 tttttacagc aaattttgga gaagatggac cggaaatgcg cgggaataaa ttagtaaatc
    17881 atggcggtat cacatttgag actcaagaac tgccaggagc ggagcgactt gaaagttttg
    17941 gagatgtcac tctggaacct aaccaagtac gcgagtttgt aacggaatac aaaataaata
    18001 taaagaaata gaataaatta aaaagggagt gtgacagtgt cacatcccct ttttaattta
    18061 ttctatttct ttaaaggcag atcaagccag aatgatttgt ctaaacttaa caaggttagt
    18121 acaggaacag ttgcagcttt aactgtacga gtagttgttt ctggtatctg tcttgccgta
    18181 aaattgttcc acaaatccca gattgaagcg acacggaaga tggaagaagc gttgttgacg
    18241 cgttttatcg ttgaaaattc taatcctgtg attggcacgc catctgttgt ccatttgatt
    18301 ggcacatcga atcgcttaga catattgagg atttcagcgt ttgcttcttc agttgttgct
    18361 gcttcttttt tcggttcatc atattttgtc aggtcgtacg cttcgatgat cgcgttcaat
    18421 ttttgtgaat attggcgatc tgtagcataa cgtccttcca aatatttggt tgcttctttg
    18481 tagtcttttg tttccgactt ccaagttggt ttgtagaaat caggattgcc agtcagtcca
    18541 tttttgatca agtcggcata gtcttccaaa ctttccttgt aagaaggata tttacggaat
    18601 tgtgcgcgga tttggtagct ttgtccggaa ctatcttgtt caagtgtatt gaaggtcacg
    18661 ctgcttcctt tatatgatcc tttgatacca aaaaggttat gatttggttc gcttgataat
    18721 aagctgtttc cagatccact ttcaaggata gcttgagcca tcatgactga tgcgtagatt
    18781 ccttcttttt gcccgatttc ctgtgcatca tctgcaatct ttttcaagaa ctgatcagtt
    18841 gtttggtttt gactgaaatg gaacgagcca tctaatccat ctaaaataga tgagccgcct
    18901 gtcagcgaac ctgaagcagc aggtaaacct gctaagttta ctcggacagc aaaatcaggc
    18961 gtgaaatctg aaatagaagt tactcgaact ttatctcctg gttgaggcgc atggataaat
    19021 tgtccgttcc caatatagat acctacatgg tgagtaacac cggaagaagg tccccagaag
    19081 acgaggtcgc caggttgggc ctgacttact ggaatctgcg tacctgcata ttgctgttcg
    19141 cctgtccagc caccgatata atgaccggtt gctttcatat atacgtaata agtcaaacca
    19201 gaacagtcaa aagtatttgg accttttgct ccccatacat atggttttcc aagatgcttg
    19261 aatgcttctc gaacgattgc ttgttggaca ttcgttgtat ttgtaggcaa tacagcatca
    19321 attggtgatt ttacaacaaa atcagaagaa gcagaagatg gattctctat accgctttga
    19381 tttgctgtat ttggacgaga tgaagcattg ttcgttccgc cattcgatga accattgttt
    19441 ggatggtttg gttctctctg agtatttcca ttgttattcg atccagatgg gtttgtttga
    19501 ttcgaagaat tcccgctgtt cgaattattg ttattattgt ttgaattatt tgaaccatta
    19561 ttattgttgt tattacccac atctggtttg tttggcgttt ccggatctgg tgtactaggg
    19621 acttcttcac taggatcagt tggtttctct gttgaagtat ccggtccagc tttaaattct
    19681 gcagtaatag ataaattgtt cgtacctact gtaaaggtct ttgcatcata atttacttct
    19741 ttggcaccat taacagcgac tgaagcaatt tgttcacctt cagctggcgt aatagtgtaa
    19801 gttaccttcg tttccgctaa taaaccttct accgttccac tttccgtaat atccaaaggt
    19861 tgctgttcag gggaatccgc tgtcgaagca gtcagttgga tcttaccaat caaagaagga
    19921 gcaattgtaa gggaatatgt ctcggctggc ttttcatttt ctgatggatc agccggatca
    19981 atttcagttg gctcggtcga tcctgttgtt gagttagttg ttccagttgg gtcttctgta
    20041 aaagaatccg ttgtttcact agtagctgag ctggatgtag tcgtatctgt tgtgactgtt
    20101 tgatcagcta tttgattatc tacggcaaat acggtattgg tcgacaaaac agacggagca
    20161 atcagccaag tagcagctag caaacgtatc gtttttttat ttttcataat aaactagtcc
    20221 ttttcctttc attgattttc tgtcttattc agcattcatt agacattttt tggaacagat
    20281 aatcgtgtcg aaaagctttt tcttttcata aatctgtctg tgtattctaa ataaaacaat
    20341 ttgtaaataa gcaacgagca ttcattcgtt tttctttgac gttcatttta ttgcatagac
    20401 cacctttgtt tggggataaa caagtgggga taaaaatggt tatgcatatg taaattatac
    20461 caaagtttgg aaagtatcac aaaaatttat aaaaataatg atcctaaaaa gaaaaagact
    20521 gaaatatgtg ataaacatct catacttcag tctttttcat taactattca taagacatta
    20581 ggtcttcatc aaacccgcta acgagagtag tgatcattgc tacgactaga ctaacagcca
    20641 gtcctgctaa gtaccagaaa aaagtaccgg aaatgaatgc aggcaatgtg gtcagactac
    20701 caaatacaaa agcgatcgct ttcacttggg caaatcccat tacagctcca ccagcagctg
    20761 caccaatgca agcagcaaca aatggttttt tcaatgggat cgcaattccg taaacagttg
    20821 gttcggtcac tcccgcaagt aaaatcgaag caaaagcaga accggagatc gaacgggttt
    20881 ttgaacgttt acttcgcaga aatacaccta aagctgcacc agccattcca aaattggctg
    20941 ctcctgtcaa cggaacgatt cggtcgaacc cataagcaga gatattactg atcatgacag
    21001 ggtttacagc ccattggata ccaaatatta ccaaaatatt ccaaccacca gcgatgattg
    21061 cgccactgat cggtccgtta atatccatca tccaagtaat tgcggcagct aaaccttcgc
    21121 caaggtaaac acccgcaggc ccgaatacca ttaacgtcaa aggaaccgtg ataactaatg
    21181 aaagtaaagg tacaaatact aattgcatat tttcgcgaat atattttttg aggaattttt
    21241 caacaaaaga ataaaagaaa atacctaaaa tcgccggcat gacagtagac gtatactgca
    21301 tcagtactac aggaatcccc agaaaatcag tagctgcttt gccactgtct gaaagtaaag
    21361 aggtcagatt cggttcaatc agtgctgcag caatgacagc cgcaatatat ccattcactt
    21421 taaacgtttt ggcagcagaa aaagcaagaa agattggcag aaaataaaag acggcattcg
    21481 acgcagcaga caaaatatga taagttccgc ttgtttcact aagccagcca atcgtagtcg
    21541 ctaaaacaac cagacctttt aatataccag aaccggcaaa cagcggaatg atcggcgtaa
    21601 agatttccga tatcaaacca aatagttttt cgatcggatt tagcttttct ttcggagctg
    21661 aatgatcgat ttgacgcgtc aattccttgt aagcaggagc caatccctga tccatgatta
    21721 tttctgcata tctatcgagt aaaatgaaat acttaatgga agggatttgc tgttttaatt
    21781 tttctgcatt ggctactggc tgttttttca atttgatacg aagccgagtc gcacatggaa
    21841 ggacagaatc aatattgtct tttcctccca actgttcaat cagcatatga atctgctcgg
    21901 acagtaccat ctgttcagga ttcattgtcg tttccattag aagaccactc cactcactaa
    21961 tataatattg gcgtaaggtg tcatttcgcc tgtacgaata aatgcatgac agttattcaa
    22021 ctcttttttc atttcttcat gtgggataaa gctaatcggt gtatctggta acaataattt
    22081 gattttttcc aatatttccg ggttcattgt ctttatttct tccgccaatt caatcgattg
    22141 tacctcaagt tcttctaaaa cgttttctaa aacagataaa aaacttggaa gaccgtttga
    22201 gacagccaaa tctatttttt cagtaccaaa ggggacaggc atgcctgcat ccccgatact
    22261 taatttatca aagtgcccca tttgtgcgat tactcgtgaa atatctgaat tgattacttt
    22321 tccttttttc atgtttgttt cttcctctca ttgttaattt tagactgctg attgttctaa
    22381 agcttcgcgg taagggatag aaggttgcgc accataagac tgcacagcaa cagaagaggc
    22441 tagatttcca taaaggatcg cttctttcaa gttactaagg tctggctgaa gtgtgctgct
    22501 taatgcgcca ataaatgtat cacctgcggc tgttgtgtca acggcatcca ctttaaaagc
    22561 agggacgata ccgtgttctt tttctgtatg atagaaagcg ccggcactgc ctagtgtaat
    22621 gattactgtt ccaataccta attcatggag tttttcggct gctgcgacca aactgttatg
    22681 atctgtcact ctgattcctg taatgatttc tgtttctgtt tcatttggta taatgatatc
    22741 tgtcttttca agtagttcag taggaatcgt ttcacgagct ggtgcaggat tcaggatcgt
    22801 tgtttttcct gcgtcttttg caatagaaaa agctaggatc gtcgcatcta agctactttc
    22861 aaactgagca ataataaagt cactgtttgt aatcagttgc ttgtttttta ggacttcttg
    22921 ttcatggaaa gcattatttg cccctgcatg gatcaagata ctattttctc ctgctgcgtc
    22981 taccataatc attgcttgtc cggttgtggc gccttggatt tcagctatcc cagatgtatc
    23041 gatgttttct tttgtcagta gatctaataa ctgttgtcct tcgctgtcag ccccaacgcc
    23101 tccaataaaa gatgtccgtg cgcctgaacg tttggctgcc actgcttggt tggcaccttt
    23161 acctccgcca gcgtgaaaaa tctcatgcgc atgcatcgtt tcgcctggct tgggcatgtt
    23221 ggttaaacga agggtagtgt ccatattaat acttccaatt actgtaaccg tgttcatttt
    23281 acaaacctcc aactatctca tttattttga tgggaaaatt attttttaaa acgttttagt
    23341 aaaacgtttt aatagttcga taaaaatata gcacaccttg aaagctattt caagggtgca
    23401 gttgaaaatc ttttttctaa tcgtacaggt aatctttttt cttcccattc tttttctggg
    23461 aattggatcc gatctaacaa taacttggca gatgtttgtc ccaattcgaa gattggttgt
    23521 gcgatcgttg tcagtttcgg cttgatatac tcgcacatat ctatattatc atagccaata
    23581 atgctgtagt cttcagggat gctttttcca gcttcctcta atccgcgata taatccaaaa
    23641 gctaattcat catttaaagc aaacacacca gttgcagcag aatcaagaag ttctgctgtg
    23701 atctggtagc caccttgttt tgagaactgt gtaggtaaga ggatcagttg gtcgtgaggg
    23761 atttggtaaa catcaagagc agatttaaac ccctcaatcc gagcgtggac attttccggt
    23821 ggattttcag gatagacaag ggcgatcgtt tgatgtccta gactaagcaa gtgcatgccc
    23881 gctaggtaac caccgcgaaa atcgtctgtt cgtacggcat cactaaatcc ttcagatttt
    23941 ttctgatcca aaacaatgaa gggccggcct tgttttttca aattttcgtt gattgcatct
    24001 gtagagacag cagaagtcgc gataatgaat ccatccacac ctcgacgtgt gagctcggct
    24061 agatattcga tttctttttg atgatcagaa tcagcattac ataatatcgt gacgaaattc
    24121 tgcttataca agatatcctc aattcctcgc atcagtgtac tgaagaatgg attcgtgata
    24181 tcaggaacga gtacaccaat tgttttcgtt tccttggtaa tcatttgtct agcaaaatag
    24241 tcaggctgat agcctaattc ttctttggca gctaaaactt tctgaacagt tttcggactg
    24301 aatttctccg tatttccatt taatatcaag gagacagttg tgattgaaac gccggaaagt
    24361 ttagcgactt ctttgattgt gatctttttt ttcaccatgt tcatactcct atctaaatcc
    24421 tgtggttatt ttcccatgaa atcaaaaaga agtaaatgaa aatcacgtgt gccagtactt
    24481 atttgctttg ttggatagct tcgattattt gtttcgttga gcgtactcgt gcagttttcg
    24541 gaaatatctt ttttatgaac aattgatggg attctttgtc acgatcactg caagcatctt
    24601 cagcaagcac gatatggtac ccgtgttgaa aggcatctaa tgcagtagca tatacaccgt
    24661 ttgttgtcgc tacaccgctt aaaatgatag tttcgattcc acgccggcga agttgaagat
    24721 caagagaagt accaaaaaaa gcacttggat tgtattttgt gatagtcaac atattatctg
    24781 tatctttcaa agaatccttc aaaagtaaat cagtgaattc tggaggtaca gaagcagtca
    24841 ttccacccat atcagtttgt tgactcaaat aagggaaagt ggagatgtct acgttcacta
    24901 aaactttcaa ggcagcggta cgtttcaatg ttcttactaa caaatcattg tttgtcagaa
    24961 tagatgctgc agtgtgtgga gagagtgtac cgttatttac gatctctttt tgcatgtcga
    25021 tcgcgacaaa agcagttttt gataaatcaa aaatcatatt ttcctttaaa tcattcatga
    25081 tgttccttct ttcaaataac aatgtttttt atgtaagtaa atcataaatc gtttatttgt
    25141 caactaaatt aaaggattcc tttctttagt ctagagaaat tcagtggtaa aataaataag
    25201 tgtgagaaaa cgcattcgat gcatagatat agcgagaaat atcgtgaaaa tggaggaatc
    25261 agagtgaagt atgtcgaagt aaaaaatgaa tacaaacgat acaaaatggg agaaacgacc
    25321 attacagcaa atgacgatat ttctttttca attgaaaaag gcgaattagt gattatactt
    25381 ggtccaagtg gagcaggaaa gtcaacgatt cttaatattt taggtgggat ggatacacct
    25441 gatgaaggtc agatcattat tgatgacaca gatattgcgc aattttcaga taaacagctt
    25501 actgcttacc gacgaacaga tgtagggttc gttttccaat tctacaatct cgttcctaat
    25561 ctaacagcaa aagaaaatgt ggaattggca acggaagttt ctcctgatgc gcttgatcct
    25621 gtagaggtat tgaggcaagt gggcctagct catcgattga ataactttcc gtcccaatta
    25681 tcaggaggcg aacagcagag ggtttcaatt gctcgtgcac tagctaaaaa tcccaaactt
    25741 cttttatgtg atgaaccgac aggcgcgctg gattttgaaa cgggcaagca agtattgaaa
    25801 ttattgcaaa acgctagcag acaacacggc aataccgttt tgatcattac acataattct
    25861 gctttagcgc ccatcgctga tagagtcatt cacattaatg atgctaaagt aaggtctgtt
    25921 gaattaaatg atcatccttc atccattgat gagattgtat ggtaggggga ttttatgaaa
    25981 acaagaacat atcttaaagc aggttttcgc gaaattcggc aatctaaagg acgattcatt
    26041 gcaatcatcc ttattgtcat gctaggaaca cttttatttg taggtgtcaa aactgctgga
    26101 cctgtcatgc aaaaaacgat ggatcactat gttggtacag caggactttc tgatttgcaa
    26161 atcgtttcta ctggtggctt gacacaaaaa gatattgctc aagcagaaaa gatcccagat
    26221 gcaaaagtag aaacaggaaa acagatctat tattccaata ctggcaaaaa cgaagtgatt
    26281 caaatatttt cttataacaa aaataacaag cagaacaagc tacaattaac tgatggaaaa
    26341 ctcccggaaa aaccaaacca gcttgtattg gatgaaaaag cggaagatga agggtataaa
    26401 atcggtgata tttatcagat tgattcagat gaattgaaag aaaaagagta taccatcacg
    26461 ggctttgtcc gttctccatt gttcatcaac aatttggaga gaggatacgc gaacgtcgga
    26521 aatggtagcg tcgattattt tgtctattta cctgaatccg tttttaaaac agatatttat
    26581 tctgtcttat atcttgattt tacaaacgta aagaatttga atacgtacag caaagcttac
    26641 aaagataaaa tggagcaaaa tcaagaaaag gcagaaaagt atttacaaga tcgacccgaa
    26701 gaacgcttag aagagctgaa aaaatcggcc aacgaagaat tagaaccggc acagcaaaaa
    26761 atagcggatg gcaaagcaca aacaacgcaa gcaagaacac ggttagaaga tgctaaaaaa
    26821 cagttagcgc aacagtcagc aactatccag cagcttcctg aagcgcaacg aacaatcgct
    26881 gttcaaacat tatctcaaca agaagctcaa cttgctgaac aagaaaggca attagttgag
    26941 aaagaacgtg aactggcctc tgcagaggaa gaattgaatc gaaatgcaga aaaaattgaa
    27001 aatttaacta aaccatcata cctatacaat gaacgttcag aaaatgtcgg ttttcaagaa
    27061 tttggtgatc tgtctgatcg tatcgctgcg attgccaatg tttttcctgt tttctttttc
    27121 tttattgccg cattgatcac ctttacgaca atgacacgta tggtagaaga aaaccgcagg
    27181 gaaatcggga cattaaaggc gttaggttat acgaaagttg aaatcgcaaa aaaatatgca
    27241 atctatgcaa gtctagcctc agggataggt attgttttag gaacgatatt aggaacgaat
    27301 cttttgccaa ggatcatttt tgagctgtct aacgagcggt atgatattgg gagtgcgctt
    27361 attttttatg actggccgcc gattttacaa gcagctgccg cattcttcat tgccgcattt
    27421 ggcgctgcaa tgatcgtttt attcaaagat ttaagagaac ggcctgctgc attgcttcaa
    27481 ccgaaagcac cgaagccagg gaaacgcatt tttcttgaat acatcactcc gctgtggtca
    27541 cgccttagct ttaatcaaaa aatcagttac cgaaatctct tccgatataa gtcaagaatg
    27601 cttatggcga ttatcggaat tgctggatgt gccgggctga tggttgcagg cgtgggattg
    27661 aaagattctc taagttctgt ttcagccaaa caatttggac cgatcattga ctatcaagca
    27721 atcgttacat tggattcatc cacggaagat agtcgtcaaa aagcagcgga tatgctgcag
    27781 aagcaagaaa aagtaaatga gatcctagct attcatactc aaaccgtaga attgagaaaa
    27841 aaaggacatg cttcgcaaag tctgacagtg atcgtaccaa gtaaaacagc tgatttggat
    27901 cgttttatcc atttaactga tcttgaagag aacccacgct ccttgcctaa aacaggaatc
    27961 gctattacgc aaaaagtagc agaactattt gacttatcta caggagatca tatttcgctt
    28021 tatgatgaag atcaaaaaga atggaaagtc gaagtaaaag aaatcgtgaa aaactatcta
    28081 ggtagcttta tttatatgtc ccctgaatat tatgcttcag ttactgatca atcgatgatg
    28141 gataatgcat ttttgctgcg tacagataag atgacaacaa aagaagaaga aatgctttcc
    28201 gagaaactgc ttgccacaga cgctgtgaca aatacgtctt tcatgtccaa acaaatcgaa
    28261 acgcaagaag aatcaatggc gaacttagac tcggttgtct taatctttgt cgtattatca
    28321 ggactgctgg cttttatcgt cttgtataat ctaactaata tcaatatttc cgagcgtgta
    28381 cgcgaattat ctacaataaa agtccttgga ttttttgata aagaagtcac gatgtacatt
    28441 gttcgagaaa atatcatctt tactctttta ggaatcatcg gaggatttgg tgtaggatat
    28501 atattgactg acttcatctt gcaacaagcg tctatggaga atgtcatctt tccattagtg
    28561 atcacatggt gggcttatgt cttatcagca ggattaacta tcgtatttac ggttattgtg
    28621 atgattgtta cccatttcaa attaaagcat atcgatatga ttgatgcgtt gaaatcgaat
    28681 gaataaaaac agaggttgtg aaatcagcgg tttgacctga gtattagaga aacaaacggc
    28741 aaaatagttt ttcatatttt gccgtttttt gagctaatac cgaaggacag ctgattgaac
    28801 accatgaatc agaggttgta aaaaagccgt cctgcatcga gcaaaaagaa tactcaaata
    28861 aaattagctc ctcatgtttt acatttgaga agactgattg ccgtagataa aagcttttga
    28921 acaccattta tagaagaaac aagaatattt tgctatttta aacaagagga tagacaaata
    28981 catgtctgat ctcttgtttt ttattgggca acagacctct tagaatgtat aaagataaat
    29041 tttacaaacg ctttcggttc agttataata ataaatgata acttgtatat ataagttgtg
    29101 gtaggtaata aatcagttga atggaggtaa atatccatga catttaaaga caaagtcatt
    29161 taccaaatct atcccaaatc ttacaaagac agtaatggtg atggaattgg agatttaaaa
    29221 ggaatcaaag aaaaactccc gtatctgaat gatctaggca tcgacatgat ttggctaaac
    29281 cctatttatc caagccctca aaaagacaac ggttatgata tctctgatta cacagccatc
    29341 gatcctatct ttggtacgat ggaggaattc gaacagctaa tagccgaagc aaagaaatac
    29401 cggatagaaa tcatgctcga tatggtgctg aatcacgttt cgacagaaca tgaatggttc
    29461 aaaaaagcac tagcagggga ccagcattat caggacttct tcattttaag agaagagcca
    29521 acggattggg tatcaaaatt tggtggaagt gcttggtcgc catttggaga tacggggaaa
    29581 tattatttgc acttatatga tcggacacaa gctgacttga actggcggaa ccaagcagta
    29641 agagaggaac tattcaaagt tgttcgtttt tggatggaaa aaggggtaaa aggattccgt
    29701 ttcgatgtta tcaatgttat cggtaaagac gaacaattga aaaataataa agaaaatgat
    29761 ggcaaacctg aatatacgga caaaccaatc acccatacgt atctaaaaga attgaaccaa
    29821 gcaacgtttg ggacggattc cactatcatc acagtcggtg aaatgagctc tacgacgatc
    29881 gaaaattgta tcttgtatac agaacctagt agagaagaat tatcaatggt ctttaatttc
    29941 catcatttga aagtcgatta tgaaaatggg aataaatggt ctactcctcc atttgatttt
    30001 gcagaattaa agcgactatt tcatacatgg ggagaaaaga tgagtgaggg taacggctgg
    30061 aatgctctat tttttaataa tcatgatcag ccacgtgcgc tcaatcgatt tgtagctatc
    30121 gatcagtatc gaaaacaagg agcagagatg ctagcaacca tgatccattt gaaccgtggg
    30181 acgccctata tttatatggg agaagaaatc ggcatgatcg acccagacta ttcatcgatt
    30241 tccgactata ttgacgtaga aagtttgaat gcttataagt tactccttga acaaggattc
    30301 acagaaaaag aagcgtttcg tcggatcaaa gcaaaatctc gcgataactc tcgaacaccc
    30361 atgcaatggt cagacacaga acaagcagga tttactacag ggaaaccttg gttaaaagtt
    30421 ggaggcaagc tagaagagat taatgtagaa aaagaactat cttctgaaga ttctattttg
    30481 tcctattaca agaaattgat tcggctgaga aaaacatatc caatcgttgc acaaggagat
    30541 tatcatgctt atgaagcaaa tcatccggaa gtttatggct ttcttcgcca atttgaagga
    30601 cagcagctgc ttgtattaac aaatttctat gataaagata caaggatcgc catcccagaa
    30661 ggattcacag aagccaatat tcttatcgat aattattccg atactgttct tcatcaaagt
    30721 ctggagctaa aaccatacca ggcaattgct ttgctgaaaa attaaaacaa aaacacaaaa
    30781 cgtcgttcct acgagctatt ctcgtaagat cgacgttttg tgttttattt aaaataatct
    30841 tcttcagaaa atgaagagtt ttcatactct cctttatcgc cataaaattt attgtagcgt
    30901 tgtttgaatt tacggaaaat aaaagtaacg agtaatttga ctaacgtata gataggaata
    30961 ccaaaaataa cgcccacaat tcccattaga tcacccatga caagtaaaac gattaagatc
    31021 gtaatcggat ggatctgtaa acgatcaccc attactcgag gaatcaccaa gtcaccgtgg
    31081 agaagttgta cggcaaacca gacaatgaca aatttgacag ccataaaagt agagtcttgg
    31141 aatgcaatga tcaaacctgg aaagaaggcg ataaacggcc caatatatgg aatgatacat
    31201 aacaacccag cagaaatagc taaaacacta gcaaattcta atccgatcag taagaaacaa
    31261 acccagtaga ctgctccaag gataaatgaa gcaatgattt gcccctttag aaatgaaccc
    31321 aattgttgat tagcaatctt tgtcaaattt ttaaaatctg tacgaaatgc tggtgggaca
    31381 atcgctaaaa ctgactgata aaatttttga ggatctctca aaaggaaaaa agcgacaatt
    31441 ggaccagtaa ataaagtaat aaaaatagct gtaacagttg aaaaaatgtt gctgatccgt
    31501 tgtgcgccac tttcccaata atttccaata aatccagcta tatcagacgt cacgtcgtca
    31561 atagaagcga aaaattgatt aaatgaatcg gcaaaaggtg ttttctccaa aaattgtcgg
    31621 agactctctt gaaaatcttg aaacaaatct ggcaaactac tgatcaatgt ctttgcctgt
    31681 tcttcaagaa aaggaataag ccatatgctt ccaagcccca ataaaaataa aataatcaca
    31741 taaacgataa tgactgacaa gttcctcgaa aggtgcttgc tcaaacgttt gatgactggt
    31801 tccaaaagat aatacaagat cagtgcaaac aataatgggg gcaagatagt agcgataatg
    31861 attccgacag gcttgaatat aaacgagatc tgatggaaaa aataaatgat cagcgcaagt
    31921 aagataacta ttcctaaaac atagtaagag gtttttcctc ctaaaaagcg gatcaaacga
    31981 ttcgttgtat ctgtttcttt tttcactctt tttcctcctt tatctataaa ttcattatag
    32041 acaaaagcgg gtataaaagg aaaatgatag aggttgattg caaaaatatc gtcaatcatt
    32101 catataaact ttctcatcaa ttaaaataag aaaacgcttg acagttcttt taaccatatg
    32161 ataaattaaa tcctgttgct aaaacgtaac tattacggtt tgcgaaaagc gaatcggaac
    32221 attcaaatga aagaagatga gaagaggagt gtcataaatg aaacgattga taggtatatt
    32281 ggccatgctg gttttagcag gtatgttaac tgcttgcggg gcaagtggga aagccgagga
    32341 cagtaaagaa aaattgagcg tgatgacgac cttttatccc atgtatgatt ttacaaaagc
    32401 aatcgtcggg gatgaaggag aagtagagtt attgattcca gcagggactg attcccacga
    32461 ttatgaacct tctgctaaag acatggcaaa gatccaagat acagatatct ttgtttataa
    32521 tgatgaaaac atggaaacat gggtccccgc aatccaaaaa acattacaag aaggcaatgt
    32581 ccatacgata aaagcgacag aaggtatgct tttacttccg ggaagtgaag aaggacatga
    32641 tcatgaccat gaacacgggg aagaaggcca tacacatgag ctagacccac atgtatggct
    32701 agctccaagt ttagcaatca agcaggtagc aaacatacgt gatcagctga ttgaagctta
    32761 cccagaaaaa caggaagtat ggacaaaaaa tgcagcagcc tataccgaga aacttcaagc
    32821 actccatcag ctttatcaag aaacctttaa gcaagcaaaa caaagatctt ttgtcacgca
    32881 acatgctgca ttcaactatc tagcgttaga atatggattg aatcaagtat cgattgctgg
    32941 tctttcttct agtgaagaac cgtctgcggc gagaattgct gaactgaaac actttgttaa
    33001 agaacatgga atcaactata tttattttga agaaaacgcc aaagatagta ttgccagaac
    33061 gttagcaaac gaagcaggtg tatctttaga agtattgaat cctttggaag gattgacgaa
    33121 tgaacaaata gaaaatggag aaaactatct ttctatcatg gaagcaaacc tcgaagcgtt
    33181 gaaaaaaacg acagagacag aaaacccgct agaagatact ttgaccccca aaaaagaaaa
    33241 gagcgtctac aacggttatt ttgaagacga ggatgtacaa gatcgctctc tttcagattg
    33301 ggcaggaact tggcaaacag tagatacgta tgtagaagat gggacttttg atcctgtttt
    33361 tgaatataaa gaaaaattga atcaggataa gacagcacaa gaatataaag aatattatac
    33421 gaagggctat caaacagata ttgcttcaat caagatcagt gagaaagaga tggcatttac
    33481 gtttaagaat ggaacaacga aacgttcaaa ttatcgttat gtagggaaag aaatcttgac
    33541 ctacgaggca ggaaaccgtg gcgtaaggta tctattcgaa gcagaagata aggaaagtgg
    33601 cgcttttaga tatattcaat tcagtgatca cacgattgca ccggctgact ccgaacattt
    33661 tcatttatat gcaggaaatg aaagtcaaga agtattgctg aaagaaatgg agaattggcc
    33721 aacattttat ccagatacaa tggatggacg tgaaattgca caggaaatgc ttttgcactg
    33781 ataggcaaaa aagaaccgaa gggtttggat cggctggtca tttagtcggt ccaaactatt
    33841 cggttctttt tatgaaatca atttctttaa tccacggata gaggctggga tggtctcgcc
    33901 gtttgccaac gtgacttctc tggttttttt attaatcgac cgcacatttt gtgtattgat
    33961 aacataggat ttatgacaac ggataaaatt ccgatgcatt ttctcgattt ctttgatctt
    34021 ctcatagaat tgtaattggg catgagtcaa atggacttcc agtttatgtg gcgctcctag
    34081 cgaagtagaa aaatattgga tgtctttgat cggtaaaaat ttgatctcat cattaaactc
    34141 tattttgaag atatcttttt ggatttggga catttgaaaa tcttcgaaaa ttttgctcag
    34201 gatatgctcg acattttctt ttaaatcata aagatcttct ttgacgatat aatcagtcgg
    34261 ttcgatgttg ctttttaaga ttttcatcga catttccgta tgggaagtca catagattat
    34321 ttttcctaaa ggatctaatt cacggatcaa tttaccgatc gctacaccat ccatttcact
    34381 gtcttctagt tcgatatcta aaaagtaaat accaaaagaa gaagttctga tcttggctgc
    34441 attgagaagt tcttccggat cagaggtaga aatatggaca taactgtcta agttttcaat
    34501 catgattcta tttttgatca ccgttgataa aacttctaat tgttttggat cgtcttcaca
    34561 aatataaatg ggaatcatat cattactcct ttattttatt tgtatataaa tcgtttgaga
    34621 aaaacgctgg ttttcaattg atgtttcaag gaaaagataa ggattggtct ttgtcaattc
    34681 atccaagata aacaagccaa ggccttcgtt ttttggattt gtttttgttg agaacccttt
    34741 ttgtttcaac tggtttaacg gtaatgtatt tgttgttgta ttgatcacac gaatcatcac
    34801 ggaatgattc ttcttgagta tggtcaattc gatttttttc ttctttgcag cactagctcc
    34861 ttcaatcgca ttgtccaaga taataccaag catacgtaca aggtttaccg tatgtttcgt
    34921 atccagttcg attggctcag gaaaatgaag ctggacgatc aacccttttt cctgtgccat
    34981 catgagtttt aatgacagta aactacggat ctcaggaact ttcatattat ccaacatact
    35041 tagattggcc ggaaaaaggt tcatcatctg gcgtgtaggt aatatcgttt gatcataata
    35101 agaccgtaat ccttctaagt cgccttctga aatatagctg tgaagagaaa aaagcagatt
    35161 ttggtaatca tgtttgaatt ctctcaagtc ttgatagttt ttttctagat ctttgatata
    35221 atcctgttgc atcctgactt gttgctctaa taactgatca gctaatttct tattagagat
    35281 tttccaataa taaaccaaga tgatcaggcc aacacacaga tatagaatga aaaaactcgt
    35341 attcaaagct aagacatcag gtgtttcacc agaaaaacgg gtataaaaaa taatgatata
    35401 gtatgtaaat aatatcaatg tcccgatcgt accgatcata cggcggtcca cagtgtgaaa
    35461 ccaagtctct aacgattttt ttaaacaaaa agctaataaa gcagataaaa aagcggataa
    35521 gacaatgtga aaatactgca atgaatctcc tggttcaata accgaagatt tcaaaacaaa
    35581 aaaatcgccg atgcttgtta agtgatctcc taaaagcgac gtcaataacc caaaaggaag
    35641 cgcgtaaacc aattgttgac gcgaagtcga aaagaagaaa aaagtaagca tcagcattcc
    35701 tatagcaatt agagcagtaa aaatccctaa aatcgaatag acccatccaa tcaaaataca
    35761 agaaatcaga atgactcccg caaacagata tttgtatcgg atgtgatggt caatcaataa
    35821 gatacaaatt gtgtaaatca aatattgcaa cgctatggac cataaaaaca taaagtacag
    35881 ctcccattga tttttaccaa attatagcac aattggcgta ttattttttt aatttttcag
    35941 ggattttgaa ttcagaactc ataccaaagc agcagccaga tacaaaaaag tcagataagt
    36001 tagttaattg tttaatgatt gtttttttca tgaaagattc ctccaaaatt catcaagtag
    36061 tttgtaatag gaagcaacgt agctatttct aaaacaatcc caagtagcaa ataggtagaa
    36121 aagtaagaag ctgagaaaaa taacgtaatg agagaaaaaa ttagaaacat gctgatcgcc
    36181 ttctttaata atgggggacg tttctcgggt tcaatgggat tgattgctgt acctcttgat
    36241 ccatagcgaa gcagtaacaa aaagcagctg attaacaaaa agaccatcat tgggaaggag
    36301 atagtcaatt gcagatgttt catcaccaag ggaacgcccc ataaataaag tagtgtccac
    36361 agcagacaaa cgaattcaga gtcggaatgc aatccataag catatctgcg gatgcagata
    36421 taagaaagaa aggtgattcc tgtttccgcc catgagcctg tcaccagaga aaagactaga
    36481 acgaccgcta gttttccaag attattcaat aaaacttcta agacaaattt tacttggaca
    36541 tacaccatat cttcttccga tttgtctccg ctgaataagg cttctaataa tttgttcaca
    36601 actttatctt tcatctcata cgtacctcca ccacaaattt tatgctaaaa aaaataaaaa
    36661 acgtcttttg tttcataaaa agtggttttg acatcaaaac cgtcatgatc tcctaaaaaa
    36721 atcttcgttt tccaagaacc ttaccaaaaa aagtgacagt tttgatacga aaagtacttt
    36781 ttatgacaag tttgtgcttt ttcgagtgat ttatgttaaa aaattactga ccttataaaa
    36841 ggtgatggag ggattcttat ggaaaatgaa caattgtttg aagtcggcga aacatatgca
    36901 tttaaatctg atttatttga atcaccaata aaaggaaaaa tagaaaaaat ctatgaaaat
    36961 agtgtgatga tacgtgtcat gaaatgcgca gtagaagaca atgataccgc tcataatctg
    37021 cactggcagt tagttgtacg caaatcaagt acaatagaag aataaaaaca gataaaatgt
    37081 tgagagcata aagaggttgt gagtctcccg tttagctctg agttacaagg aataatgtta
    37141 aaaaacagct tttcatgttt tatgaatatt gccttgtgac cgaggtgttg gcaggagaat
    37201 actgtttatt tgaaaaaagg gctgcgacaa gacttttgtc acagccttta ttttcatgaa
    37261 taggagttac ttttggctac ttttagagaa gtagctttta aggagcagat aaagtcaagg
    37321 cttttatttc tataaatgaa gtagtaaaat gaagaacaga ttttattaca ggaaggatgc
    37381 cgataattgt gatcattgtt gcaggaacga tcggtgcagg gaaaagcaca ctaactgaaa
    37441 tgcttgccca agatttagaa acaaaacctt tttatgagaa cgtggaagat aatgaagtat
    37501 tgccgctatt ttattctaat ccagaaaagt atactttttt attacagatt ttctttttga
    37561 acaaacgctt tttggcaatc aaagatgctt tcagccatga tgacaacgta ctagaccgct
    37621 ccatctacga agatagtatg ctgtttcatt tgaatgcaga tttagggcgt gtttctgaag
    37681 tagaagtaaa gcagtatgaa ggtcttttag aaacgatgct gaaggagtta gaagaaattt
    37741 cgccacaaaa gaaaccagat ctactggttt atattcgtgt atcctttgaa actatgttag
    37801 cgagaatcaa aaaaagaggc cgggaatatg aacagctaga acaagatcct gaactctatt
    37861 cctactataa agaactcaat cgacgatacg aagagtggta tgaacagttt gatatatgtc
    37921 ccaaaatagt gatcgatggg gacaaatatg atttcgtagc cgatccggca tgtggagaac
    37981 aaatcgtaca agaaatcaag atgcgggcaa agaaaatgac agaagaggca gatgcccagt
    38041 cgatccgcta cactacaaat aacccgaaag caaagggaat ctttacaact aaataatata
    38101 aaaactaagc aaattgctca ctcgcagata tttctctgtg agcagcatct tgcttagttt
    38161 ttttgattca ttgagatcaa atagtgaacc gattcgtatg ataaaattgc cataaatgaa
    38221 atgtctgagt gagggccatg atcaaaaata aaatggaaac gatcaaaatc gaatgggcgc
    38281 caaacagatg atgacagaaa acaaggacaa tagctcctgc gataaaggca agaacgacac
    38341 ttagatagtg gaaaaatcga tcaaaatctg ctttttcttt agaaatacaa taatcatata
    38401 agttcgttgc tacccctttt aaatttccag ttgtaaataa attagtgtag gcacgcccgt
    38461 tgattttatc aaaagctacc cactggatcg atgcagtaaa agcaatcaaa atcgttacta
    38521 atgcgggatg ctcatggacg ggtgtcaaac taacaaagaa aaaaatcact gcttcataat
    38581 atagaacaaa caagcgccag aaatgttttt ctttttttct aaaataatca attagatact
    38641 ttgttagaag aatccctaag aaaaagaaaa gggtagacaa tactttttta ccaacactta
    38701 gccattctcc gtcaaatgct tggatgatcg atagaatgat attgccagtt tgagcagagg
    38761 caaaagcacc atattggata taagtataac tgtccatggc tcctccgata aatgtcagca
    38821 aaagtcctat tgtacgcccc tcgtgaaagg aagtctgcat ttttttcatc accttttatg
    38881 aatatttttg tcttccttat cttagcataa acgattgaaa aaaaggaaaa attttcagaa
    38941 aactaaaatc atatcgcttc ccattttcat ttttagaaag gtctgttagt ataaagaaaa
    39001 aatagacaac gaaactttaa ataaccaact tgaaataaac aaattcaaag aagaaagatg
    39061 ggaaggaaat caatcagttg aatgaaaaag aaattctccg attacaaaaa gaattgaaac
    39121 gctgggagaa caagtataaa aagcttcaac aagtctttcg gctacaagaa gaaatcattg
    39181 ctacctatga agcggcttat ggcgaagcac ccggacttat tgaggaagaa gtacaagtaa
    39241 aagaaagtga aggaaacagc tctttcttta aaatgatgga gaaacgttcc tataatcgct
    39301 tcaatcaaga acaaaaagca gctatcacat atgatatgaa gaaacatctt cgaatcatag
    39361 caggagctgg gagcggcaaa acgcaaacaa tctgtgcaaa agctgtttat ctgatgacgc
    39421 aaaaacaagt agacgaagaa cgcatactaa tgatcacttt tacaaggaac gctgcaaatg
    39481 aactaaaaaa acgagtagat aatttcagcc agagaaaaac cgctgtccat atcggaacat
    39541 tccatagtat cttttttagg atatacaatg aaatttgtcg aaaatttcct gaagtagcaa
    39601 tgcaaggaat acaaggagac ttttcaaagg atactgcaca aaaagtgaat gctgttttgc
    39661 aacagctgat acgtaaatat aatctttata tatttgatca atatggagaa aaaacgattg
    39721 cttctcggtt agactattgg cagaatatga acctttcagt agaagaaatg gttcagttag
    39781 ttaaagaaaa atatgattcc attgataaga atgcacgaca gccgatatca gaacgactgt
    39841 atggattgct cacggaactc caagaacaaa aaagaagcca gcaattgcta gagttcaatg
    39901 atgtactcca aaatctgaaa agcgctttgg agaatgagga gatccagcat tatatcggcc
    39961 aaaaatatga ttatctattc attgatgaat ttcaagatac taatccactt caatgggaaa
    40021 tcgtgaaacg gatgacaaag gaaaacagga tcaagttgat tgttgttgga gatgatgatc
    40081 agagtatcta tggattcaga ggatcagagc cagcatacat caagaacttt gaaaaagaat
    40141 atcctaccaa aactcttttc ttattaacta attatcgttc tcgggcagct attgtccaag
    40201 gagcaaatag attgatcagc tataataaaa atgatcggat accaaaggcg atgattccag
    40261 cacaaaaaga agcaggtgtt atggaagcct atttgttttc tgatactaaa gcagaaagtc
    40321 agtggctaat caaacaaatt cagacattta ttcaaaaaaa tgggaaatat aaggaatcaa
    40381 tcatattata ccgatcagct tcacaaacgc agcagcttgt ccaatctctg ctgaaaacga
    40441 atattccttt tgtactggaa gcagatagtc catatgaagg tatctttggt atcaagtctt
    40501 tccaacattt ctatcaaaaa attgttcatt ggcaaacagc actgaatctg caaaagaaaa
    40561 atcaggccta ccagcaattg ctccggcagc tgatggcaga ctgctacctg aaaaaaagtg
    40621 aatgcgatca atacttttct cctaaatatc aaaatatagc cgttgcagat tatattttgt
    40681 cgataagccc caatttaaaa tcgaaatctg cagaaatccg agagtttgag gaagcgttgc
    40741 gtaaaacaga ccagcatcaa gaaatctatt cgcttgttca aagctatctt catctgccac
    40801 gtatagctaa ggaaatcgac cagagtgatc aagaatggat acgagaagaa gtaaagcagc
    40861 atgctacttt cagaagactc caagccttat cgcaagaaac ccaagcgaca gctaaagaat
    40921 taaaaacccg cttgattgct tacagacaag gaaaacttga tgcactatgt atccagagca
    40981 ttcacaaaag taaaggtctt agttaccgaa atgtcttttt gattggttgt aacgaaggaa
    41041 gtttgcctta taacggagcg acagaaaaga aagtaatcga ctttaatgaa ataaaagcag
    41101 aaccagtaac gacgatagaa gaagaacgaa gactatttta tgttgcgatg actagagcaa
    41161 gaaatcgtct gtatctatgt gtacctcaaa tgaaaaattc aagaaaattg aaagtatcga
    41221 gatttatcaa agaaaccggg agtcgtgtga aaaaaggaaa gtgatagaag agagggtgtg
    41281 acagaagtgg tcagtttcaa gaaagaagaa ggaatgtacg aaaattgctt ctcaaatttt
    41341 tgtgaaattt cagcttattt tcgaagaagc tatttctgga acacagttta ttcggaaaag
    41401 ggaggtgtga caagaatttt gtcacacctc ccttatttat tttgaaaatg agaatactat
    41461 tatcaaaata gagaatatat agaaaaattc tcattattca aacgtaaata atcagttatt
    41521 ttgatttttt ttatatttta ttagctaata attggtattt taaaagaaat tactgtagaa
    41581 ttggattata attaaaaagg agtgagaaaa tgataaaagt atatacttcg cctagctgta
    41641 cttcctgtag aaaagcaaga gcatggttgc aagcgaatca acttgaattt gaagagaaga
    41701 atatttttgc cgaaccgtta acagaaagtg agatcaaaaa gatcttggca gcgactgaag
    41761 gaggagttca agatattatt tccactcggt cgaaaattta cgaaaagctg ggcatagatt
    41821 ttaacgaatt aactttaaag caaatgatcg tcttattcaa agaatatcct tcattattga
    41881 gacgacctat tttgattgat gaaaaaagaa tactaatcgg atttaatgaa gatgagatcc
    41941 ggtcatttgt ccctcgtgaa attcgatgtg ttgccagaaa tctgatctat ttacaaaaca
    42001 ataacatctt aaattcatag ggagggagcc ttcgtggaag tgaaagtcta tggatcagcg
    42061 cactgtgtaa caagtctgaa ggcgaaacaa tggttagaac accatcaatt gccttatcaa
    42121 tttgttgact tagaagaacg cgatctaagt acagaagaag cagaagaatt atgcagtttt
    42181 gaagaagtgc aagcagaaca gctatttgcg acttggtctg aggcttttca caacattgcg
    42241 attgaccttt cctgtgtagg aaaaaaacaa ctgatttttt tatgcacaca acataccaat
    42301 ctcctcagac gtcctttgat tattatcgat gaagttctat ttattggata caatgagcag
    42361 ttgatggaac agcttatctt aaataaatag actttaactg ttttaatcaa gtcactgagc
    42421 atttcataca gttgtaacag tcgaacactt agcatcaagc gtgttatgtg ttcttttttt
    42481 gactttattt ttctactata gagacatgct caatttatgt ggtcaaaatt caaatctagg
    42541 tggggatata gagttaaaaa tatattgaca tgtgtaaatt tacatgatat attcatttct
    42601 gttgttttaa gtagcaaagc aataaaatag tattttaaaa aacatataaa atagttgttg
    42661 acatgttaga aatgacatga taagataact gagttgttaa aaaagaacca cttgtgaagc
    42721 ttgattctat cgaaaaaaac ttcaaaaaag ttcttgacaa ataacaaatg ataagttatg
    42781 ataaatgagt tgctgtaaga tttcgaaaaa cgaaatcaaa aaaactttta aaaaagagtt
    42841 gacaattact tgtctctctg atatgatata aaagttgcta cggcagccaa aaacgaatcg
    42901 gggaacactc ctgatgaagt agacctttga aaactgaaca aagtaagaca aaccaaatgt
    42961 gtagggcgtc ttgattcaat tcaagacaac aaaca
//
LOCUS       DAFENC010000023        38599 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.023, whole genome shotgun sequence.
ACCESSION   DAFENC010000023
VERSION     DAFENC010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38599
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.023"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(98..1228)
                     /locus_tag="LP493_001548"
     CDS             complement(98..1228)
                     /locus_tag="LP493_001548"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HBL2133705.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1288..1515)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1877..3079)
                     /locus_tag="LP493_001549"
     CDS             complement(1877..3079)
                     /locus_tag="LP493_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL2133706.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3139..3342)
                     /locus_tag="LP493_001550"
     CDS             complement(3139..3342)
                     /locus_tag="LP493_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HBL2133707.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3484..4716)
                     /locus_tag="LP493_001551"
                     /pseudo
     CDS             complement(3484..4716)
                     /locus_tag="LP493_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4879..5691
                     /locus_tag="LP493_001552"
     CDS             4879..5691
                     /locus_tag="LP493_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2133708.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6715..6867)
                     /locus_tag="LP493_001553"
     CDS             complement(6715..6867)
                     /locus_tag="LP493_001553"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBL2133709.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
     gene            complement(7058..7936)
                     /locus_tag="LP493_001554"
     CDS             complement(7058..7936)
                     /locus_tag="LP493_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL2133710.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7975..9093)
                     /locus_tag="LP493_001555"
     CDS             complement(7975..9093)
                     /locus_tag="LP493_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HBL2133711.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9090..11189)
                     /locus_tag="LP493_001556"
     CDS             complement(9090..11189)
                     /locus_tag="LP493_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HBL2133712.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(11240..12061)
                     /locus_tag="LP493_001557"
     CDS             complement(11240..12061)
                     /locus_tag="LP493_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL2133713.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVMGILLSLLGIA"
     gene            complement(12058..12867)
                     /locus_tag="LP493_001558"
     CDS             complement(12058..12867)
                     /locus_tag="LP493_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2133714.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(12888..13382)
                     /locus_tag="LP493_001559"
     CDS             complement(12888..13382)
                     /locus_tag="LP493_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2133715.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13394..13882)
                     /locus_tag="LP493_001560"
     CDS             complement(13394..13882)
                     /locus_tag="LP493_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL2133716.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            complement(13959..16655)
                     /locus_tag="LP493_001561"
     CDS             complement(13959..16655)
                     /locus_tag="LP493_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL2133717.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(17083..18156)
                     /locus_tag="LP493_001562"
     CDS             complement(17083..18156)
                     /locus_tag="LP493_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL2133718.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(18153..18980)
                     /locus_tag="LP493_001563"
     CDS             complement(18153..18980)
                     /locus_tag="LP493_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2133719.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(18981..19787)
                     /locus_tag="LP493_001564"
     CDS             complement(18981..19787)
                     /locus_tag="LP493_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2133720.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(19799..20884)
                     /locus_tag="LP493_001565"
     CDS             complement(19799..20884)
                     /locus_tag="LP493_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2133721.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(20901..21443)
                     /locus_tag="LP493_001566"
     CDS             complement(20901..21443)
                     /locus_tag="LP493_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2133722.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            21701..22690
                     /locus_tag="LP493_001567"
     CDS             21701..22690
                     /locus_tag="LP493_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HBL2133723.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            22687..23424
                     /locus_tag="LP493_001568"
     CDS             22687..23424
                     /locus_tag="LP493_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HBL2133724.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            23421..23972
                     /gene="coaC"
                     /locus_tag="LP493_001569"
     CDS             23421..23972
                     /gene="coaC"
                     /locus_tag="LP493_001569"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HBL2133725.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            23988..24620
                     /locus_tag="LP493_001570"
     CDS             23988..24620
                     /locus_tag="LP493_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBL2133726.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            24705..25352
                     /locus_tag="LP493_001571"
     CDS             24705..25352
                     /locus_tag="LP493_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL2133727.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            25357..26340
                     /locus_tag="LP493_001572"
     CDS             25357..26340
                     /locus_tag="LP493_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HBL2133728.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(26743..28257)
                     /locus_tag="LP493_001573"
     CDS             complement(26743..28257)
                     /locus_tag="LP493_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HBL2133729.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            28395..29201
                     /locus_tag="LP493_001574"
     CDS             28395..29201
                     /locus_tag="LP493_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133730.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(29376..29945)
                     /locus_tag="LP493_001575"
     CDS             complement(29376..29945)
                     /locus_tag="LP493_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2133731.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(30028..32088)
                     /locus_tag="LP493_001576"
     CDS             complement(30028..32088)
                     /locus_tag="LP493_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HBL2133732.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            complement(32365..33843)
                     /locus_tag="LP493_001577"
     CDS             complement(32365..33843)
                     /locus_tag="LP493_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2133733.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(34141..35076)
                     /gene="murB"
                     /locus_tag="LP493_001578"
     CDS             complement(34141..35076)
                     /gene="murB"
                     /locus_tag="LP493_001578"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HBL2133734.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(35149..36069)
                     /locus_tag="LP493_001579"
     CDS             complement(35149..36069)
                     /locus_tag="LP493_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL2133735.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            36182..36934
                     /gene="xth"
                     /locus_tag="LP493_001580"
     CDS             36182..36934
                     /gene="xth"
                     /locus_tag="LP493_001580"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HBL2133736.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            37798..38331
                     /locus_tag="LP493_001581"
     CDS             37798..38331
                     /locus_tag="LP493_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HBL2133737.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
BASE COUNT        11574 a         7960 c         6543 g        12522 t
ORIGIN      
        1 aataaataat ataaaaggta aataaaaaag agtggatttc tccactccat gaaaagccga
       61 ctttttggga cgcttttttt tgccaagcct cacattttta tagccaaact tcttttgcga
      121 cttgctgcaa taattggatt ttcttccatt gttcttcttc tgttaaatgg tttccttctt
      181 ctgttgaagc aaacccacat tgaggactga tacttagatt ttccaatggt acaaattgtt
      241 gtgcttcttt tattcgttct tttattttct ccgtatcttc caaatctgga aacttagaag
      301 taactaatcc taaaacaact ttactttctt tgttactcca atgtcttaaa ggagtaaaat
      361 ctcctgctcg gtcagaatcg tattccaaaa agaaaccatc ataatttgtt gaaaacaact
      421 cttctgcaat gggttcatat ccaccggaaa acagccaaga agaagcgtga ttcccgcggc
      481 agatatgtgt tgtgatcgtc aaatcttctg gtttgtcttc cagtgcgtta ttgataatct
      541 ctgtacaaat atgggccatt tctttcggat caattccttt ttgaagaagt gcttctcttt
      601 tagtttgatc agctagaaac gcccaatttg tatcatcgaa ttgcaggtaa cggcaacctt
      661 tttcataaaa agcatgaatc gctgctttgt aagtagagga caagtcctca taaaaatcag
      721 atagatcagg ataaatctcc ttgatttttg aagaaccatc attagatagg atctcttgtc
      781 gtaaaatcat cgtgggacta gggatcgttg cttttgcaac aaaagtatca tctgtttcca
      841 ctacttcttt cagaaaagca aaatctttta aaaatgggtg atttggattg aaagataatt
      901 tatctactac ccgaatatta taagctggtg ctgcttttcc gtggaatgtt tgattatatc
      961 cagtttctgg aacatagcct tcgataccat ttagttcttc taaaaaatca agatgccaaa
     1021 atccacgccg aaattcacca tctgtaattc ctttgatgcc gactgctttt tggtcttcca
     1081 ctaatttttt tatttcctgg tcttcgattg cacgaagttc ttcttttgaa agtaagcctt
     1141 cttgaacttt ttttcttgct tctttgatcg attgcgggcg taagaaactt ccgacatgat
     1201 ctactgtaaa tggtctattt ttgctcattt cactcactct tttctttgtt ttttgtaaaa
     1261 aaaaatcctt ttactagcaa atactagtaa aaggacgatt atactcgtgg taccaccttt
     1321 tttcagaaaa aacattcttt ctctcagcct gacaataaaa tcagtggtct tggtaacgaa
     1381 agactgttcg tttttgccta cctttcgaca aaaaatcctc taaggccatt ttcgacagtc
     1441 aacttctagc tttttacacc aaccaaagcc tctcttgaac cattttctgt ctactttcct
     1501 tctcatcgga tactattaga ataaaattag aatagcatgt ttgaaagaaa agtcaatagg
     1561 gaataagaac aaacaaaaac taatttgtta ttcttagtaa tttgtttgtg gaatacaata
     1621 aagcttttct aatatgataa ttgttcagtc gtcctttcat cttagatcac ttccttaaaa
     1681 tgatcatacc cgtttcaacc acataaaaaa ggacttaatt ttgaaaaatt tcccatcaaa
     1741 actaagtcct ttttattata gttatgcaaa tttgcttatt ttctcgctat ttccgataca
     1801 tcttgaacag gagcaattcg actgaaaaca ctggtgcaaa agcatttatt tgtcttatgg
     1861 tagaaccgtg gaaaactcag actggtaata aattgtcatt ttttgaaaga atagcgccct
     1921 cttgaacatt atcaatcgca cttaccactt gttgatctga ctttgcatat aagtgaccgt
     1981 aagttcctaa agtgatttga atattcgcat ggcccaatcg ttcttgaata gatagcggtt
     2041 gaatattctg ctcaattaga aatgcaacat gagaatgtcg tagcgcgtga agcttaatcg
     2101 gtttgacacc cgctttttta gcagcttctt ttaaccagtt cgcaaaagaa taaggtggcg
     2161 taaatgttcc gtccaactga gcaacatatt caaaatttcc aatacgtttt tgcaagtcat
     2221 accactgtct gagttttaag gaaagcttct tccccaaccc aatcgttcga taagcacatt
     2281 tagttttggg agtcgaaaag taccaatcat cttttgtatt ataaatcaat gtcttctcaa
     2341 tcgttatcgt gtttttctca aaatctacat tcgaccaaga caaagcttca agttctccaa
     2401 tccgaatgcc agtataaaag agcatttcat acacaatctt ccgatggtgg gtttgaatct
     2461 tatcatcctt caattcattc atcacttttt gaaactcact gtgttcccaa aactcaactt
     2521 tcttattctc agaaggaagc gaagaaacat cttcaacggg atttttagca atcaccccct
     2581 ctttaacagc ccgatccaat acaattttta ggtgccctcg aatccgattg atataagatt
     2641 ttgataacgt ttcgccatta acttttttcc gtgaattacg tgactctgtc tggcttagtt
     2701 caaataacca atcctcaata tcgtgacttg taatatctcg aacacgaaaa tgatagaaaa
     2761 actgcatacg cttttcgaaa atgaattgcg cattctcata tgtttgactt ttgacctgtc
     2821 tctcgtacca ttttacaaac ctatccttgt aaaactcttc gaaagtcatt tgattggtag
     2881 aacacagttg attaggaatt gtcttgttaa aatcatgtgt ttccatgtac ttgtcataag
     2941 caattttggc atctttttgt gaagcataac ctcgtttagt cttctgaacc tttcttccat
     3001 tttcatctat acctagatac gctcggaaga accatttttt tgtcttttta tcttggtaaa
     3061 tatttttaat ttttggcatc gttccattcc tccctgtact tgagaaaagc tactttaata
     3121 gtaccgcgct tgtactgttt attccgcaac ttgaatgtga aaaagatgtt caattactcg
     3181 ggatggcacc acaccaactt ggcgattatt ataaaaatca ataccttcaa tccttgcaag
     3241 atatgccttg ctctctttaa tcattcgtgc agcttgacta ggtttaaagc ccatctctat
     3301 caaaattgca cgatttacca tgaaatcaca ttttgtttcc attctctcac ctcctgattc
     3361 tttactcctt ttaaaataat cctctttata atctattgtt tctcattcga tggttgtgtt
     3421 atactcgtct tgtcgaggcg gagtacgttg cacaacttgt tgtgtaagca gtactttgct
     3481 tttttagtag cttgttttct catttgatat actttgtaat tttcgttcat aatactcaac
     3541 ctcctcctga taatactccg ggtctgcctt catattttgg agaagtttga tctgtcttgg
     3601 attcatttct ccttgttcaa taatcaaagg caacaaggaa gaatgaaacg tttgatcgac
     3661 ctgtgcaata aaaactaatg atggtgaaac accatgaatt aaccaactca tagttttctc
     3721 aaaactttga ggaattgtat ctaaagaaat ggtgattgcg ccataattgc taataaaggc
     3781 tgcccatttg gcatcaactt ttgcacctag atcatttgga tcacggtcat aaaaacaaat
     3841 tgctccatta agtaactcaa agaacagttt ggttaaatca tgggtttttg aaataatctt
     3901 tgccaagctt tgcgctttct cttttcgata ccgtagttca aagcgattct ttacttttgc
     3961 ctcttctaaa ggaattcctc gtcgcttccg ttgttcatgg tccttctgat aaaagcaaaa
     4021 acgacactga ctcttctttg agcctaaata caaggtctca ccatttgatt cattgtttat
     4081 gatatccgta ccgccatgag attcactcac ttgaaaagtg gtccacacat ggcctagtat
     4141 taccttatgc ttaagttctg gaatgctgag actccccaca aaatcatcta aagtaaaatc
     4201 aatccgtgta aagttcccct gataatctaa taccttacga aaaaactgtt gccaatttgt
     4261 ttttcgtgtt tttagccatc ttgctaagtg tttacagcct tgacctgaaa actccatcac
     4321 agttccttta accgcatcgt caatggaata ccgaatcgtg attacttgat tccacacgta
     4381 ttggccaata tagccctttg gcgcataatc cagttcctca aaacgttcaa tgggcatttc
     4441 aataatctct tcaattagct ttaaatgttg attcgagaaa aagtgaatgg ttagataatc
     4501 aatcaaaaca cggttaactg gaacgacctc ttcttgcaaa ctatccaaca caagattcaa
     4561 tttttcttca cttaattgtc tcgttccttt ttctactttc gataataact atctcgaaat
     4621 ccccactttt tctgctaaat atcgttgtgt ccaccccctt tcttctcgag aaactcgaat
     4681 ggcttcaccg agatcatgtt gattaacttg gttcatcgac aaacctcctt ctgctattta
     4741 cttgtcaaag aacctattga acttatttta agtacatttt tattgtacgc ctgtatttat
     4801 tttaagtcaa tatgttttga ctttttttaa gtacacacgt atactaaatt taagaactta
     4861 tcctgaggag gagttttcat ggagatagac aagcaagcag tcggcaatcg aattcggcag
     4921 attcgccaag aattaaagtt gagtatggag aaatttggca aactaattgg tgatttaccg
     4981 cgaagtacag tcaataactg ggaacgtggg atcaaccttc caaaaaccga aacccttcac
     5041 caaatcgcag agataggtca tgtcaccaat gaatatcttt tgtatggtga tcaagagaat
     5101 caatacattt tagaaatgct ccaaaaaaag gcaggtaagc ttgatcctaa gattgaaggt
     5161 ctcatagtag acgaaatcaa acacgctgac cttgttagtg aaaaagaaat ggatcgaatg
     5221 attgaatttt ttattacaaa tctcattcca ccaactgaac aagaccagtt tactttccaa
     5281 tgtatcgatg aaaaaaagca gctttatctt ggttcaacta attttggtaa ggaagcccag
     5341 ctctatttgc aacatgataa tcaaaatcat attctgcaca tgatgccctt taccttctcc
     5401 aactttagtg tggatcgcat actcgtctat ttagcaaatc aaaaatccta ttcctatttt
     5461 gggaaacatt tacccaagga actaggtgag aaagccatcc ttctatactc aattaatcaa
     5521 ttgaccagcg atgtgcgaat tgccccgttg gtctattcag aagaaaccgc ttcttatcag
     5581 tacacagagg acaatcaata tctactagaa cagcaatatc tttatctacc attcgtgatg
     5641 gaagtcgaga aagaacgcct gttaaatgca gcgtatccat catcaaaatg aggtgacaaa
     5701 attgataagc acgtgacaaa gaaaatactg ctaggacact ccccaatggg tagttgtcac
     5761 agtttcctgt tctttgttag ccccctgtta gaaccggggg ctttattcct gcagtccggc
     5821 tacgccttcc tgcaatagac aaaactccag atcgggtaat tcgcttgtgg cgaaacccga
     5881 cctggagttt gtctctgtat tttgaaccct aaaaattaat caaacagact gatattctca
     5941 taatcagcgc gaaataagcc attaagtaca gttttcctac ctatttttga taacccgctg
     6001 gttagttaat attccttttc cgagagagat aaatgattgg ttaaatctat atacatctca
     6061 acctttaaaa atgttttcga aatacttcat cagtacatgt catacaaatt accagtgcat
     6121 tctcaaattc tagttcttta attgatttca gttgaggagc agttactttt ggcggaaatt
     6181 tccatttttg tccaaacctc ttcccccgat gaaatttctt tgttgcaatt attgcaatga
     6241 aaaatttttg tttcaaaaat atacataatt acttcctcca ataaaaacta tctacctctc
     6301 aaattatttt tctctaataa gaaaaacaga aaaggtaata agatacaaca gtgatgattc
     6361 ctaataaaga aaagactaca ataatatttt tctaacttat cgccttcaaa gaaatagttt
     6421 cttatttttc actaaaataa aaaatttatt gcaaaaaaaa tagaagtgac aaaattatca
     6481 atcatttcaa ggtaatataa ctacctgagt ttattatcga ttaaaatgct aactacattt
     6541 gcaagagaag cgagagttaa aggtaaatat agaatttcta cttttttagc aatagaaata
     6601 ggaataaaat atttaaaatg tatagaaact ttcttttttt ttcttgctat ctttttataa
     6661 tcacaactct ctataataga attacgattt attttatacg gctgaaaaaa tctatcacca
     6721 aaaaaattca aacattaagc caaggattat gaagtcaaca tttcgaaaaa tgaacataca
     6781 ttggtaagca actataacta ttaccacaga cataaagtaa cacaatatat tactatttaa
     6841 gtgtacgcca ccagtgaata tcctcaaggt atacagcgca caacaaaaag aaaaaaggaa
     6901 acgcagaagc atttcctttc agtgatttaa tgaaaacaac acgatttgac ttagagcctt
     6961 tttatttgaa ttcattttcg ctttatccaa cttcatttga tcatttgatt actcggttaa
     7021 atacttttga catgagtatc aatgaaacat tcattaatta tggttgctta tttcttaccg
     7081 cttttctggc caatgctaat ccgccgatta ttccggcatt atcacctaat tcgggcgtaa
     7141 taatgtagct atcaattggt ggtatttcaa catatccatt tataagctca acaaatttat
     7201 cctgaacttt tttcttcatg tgttcttgtt tcattacacc accgccaaaa ataattctat
     7261 ctggcgaaaa catcagtgtt gtattgtatg cacattgggc aaggtaaaag gcttcaatct
     7321 gccaaaacga atcgtcagcc aataaattct ggccttttac acccaaccgt ttttcaatcg
     7381 ctggtcctgc tgccatcccc tctaaacaat cttggtggaa gggacagttt cctgaaaaat
     7441 tgtcctttgg atgtcgcttg atcaacatat gccccatttc cggatgactg aacccttcca
     7501 cgaaagtccc attgaacaag gcaccacctc cgatacctgt tcccacagtg aagtatgcaa
     7561 cacctgctaa ccctttgcca gaaccagcaa catattcacc atagcaagcc gcattgacat
     7621 ctgttgtcca ttcaatcgga atattgaaat attgctttag cgttcctaca aaattgaaat
     7681 tttgccaagc aagttttggt gttgatgtga tatgaccgaa actcgttgat ttgcattgaa
     7741 tatcaattgg accaaagcag ccgaccccga tgcctgccaa ttgttcctta aaaggtttaa
     7801 aaaaatcaat gacctgcttc attgtttcaa ctggagttgt tgtgggaaaa ctgactcttt
     7861 ccaaaatcgt taattcctca gtaccgactg cacagacaaa tttagtccct ccagcttcaa
     7921 ttgccccata tatcatcata ggttcctccc ttcgaatatg tgaaaaacac ttcattaacg
     7981 cggcaagcgt tctcgatcag tgaaatgacg tttagtattt cctgaagctt ctgttgaata
     8041 ccagtaagcg acactagcaa catcgtcttg ccgctcaaat aagcgaacat catcgttgcc
     8101 gatttgttgt aaagtgaccg ataaatcttc ggtaaaacag atggggtctt gaagatgcca
     8161 acgataaaga ccatgtcgtg gcattgcgtc gtcaccaaag gcatgaacgg cattcaattt
     8221 tcccgtttca aaacgatctc ttgtggcatc tctatttgat tggtaaggat accctaaaaa
     8281 ggctgttgaa tagtttttcg catgtggacg tccgaactca tcgtactcat gaaaggccca
     8341 cgccccgcca aaataatctt ctgaacctgt tgaggttacg gtcggatact cactatcccc
     8401 atcaatgtag aatttaaact cgccttcgcc ccaccaataa cgttctaggc aggtaagcgc
     8461 aaggtaagta cccacgtaat agccttgacc ctttaatcga tcaattaact tataatcctc
     8521 ctgtaatttg gtaatgcgtt cccgatgcca atttgcgtga aaatataggc tattttcttc
     8581 caattcgtcc accaaagcgt aatttatcgt ataaaaaaat gaggacatat ccttcggatg
     8641 taaattctcg atcgtaattt tagcggatgt ttggaaaggc atttcgaaat aggaattaaa
     8701 gccccctgta ggattaacca ctatcggcaa cgagttcacc tcgcaacgct ctccaaaccc
     8761 attacaaaag aaatccccta aaggactttc aacagcaggg ctatccgacc catcccaata
     8821 aattcttaag attaaatcac gtaaaacaaa actgccaaat tctgttcgat cacgaatcgt
     8881 catccacata tgacgaatta ttcccgttcc agtaatatcc gcaatcacag tttcttcacc
     8941 agaagtcagc ggaattgcgc cacgaccttt gcggcttggt cctagctcgc ttggcaacat
     9001 cgcagcttta cctttctcgc ctgttggatt ttcgggagtg attgctcgac tctggatttt
     9061 tttaaattgg gtaatatttt ttagtatact catctttttc tcctttgaat gtgaatcgtt
     9121 tttccctttt ctacgtgaag aatttttttc gtatcactta ttttcaatgg cttttctgac
     9181 aaatttgaaa tactcaactc ggattgcgta cattcaatcg aaatgaaggc ttgaccgaac
     9241 ttcaaattct tccaagaaaa cgttaaatta tcaacaggat caatttgcaa tactcctttt
     9301 ttgaatttca atccgaaata ttgactgatc attaggctga caaaaagacc cgatgcccag
     9361 ccgcatttgc cgcagccaaa gtctcgcacg acttctcctt gttgagcctc taagcgatac
     9421 ggccaccacc accacgaacc gtctaaatct gccaaacaaa ttagttcttc taatcgggtt
     9481 acgaaagctt gagggttgtg cagctcgctc attaaaacag tgataaagcc aggaaaagtg
     9541 gcgccggatt ctaatcccca agtgatgcct ttgatttcct cgctataggt tggattgaaa
     9601 gaactagcag aaaaggccat ggtgttctga tataaatgat ctttattatc taaaaattga
     9661 taaaaaggca tcaacgtagt gtctgattct tctccatcat gcatcaataa attaattttt
     9721 ccatccacaa tcacatcact taaaaagatt aacccttgct caagaatcgg tttttgatag
     9781 tgcttcactg aataggttgt tttctcctca tcaccgattc cctccaaaaa ttgctcacca
     9841 aaaggaccat cgatagtcat ttgtttacaa attgattcct ttagtttaca ggcaatgttt
     9901 ttgtatcgct tgctaagact cagttgttct agggcttcaa aaatttctgc aagtccaata
     9961 caggccttcc aaagacaaag attgctgccg gtatgatact ttccaagtgc aaaggcgtct
    10021 gataaccaaa cagatggaaa aagcattggt tcccctgacc gacgttgagc taatatgtcc
    10081 tcaataattc ttgaagcatt cagtagaacc tgcggacacc gctcaaagaa ttttgtatcc
    10141 ccagtatgtt caaaataaag actagccagt aacgcactgg ataacgaatt actcagagaa
    10201 tgattgatac ctcctgtaaa ttttgaacca ggaaacttaa cgccatattg atcaaaccat
    10261 agaaccgttt tttgacataa ctccggttca aacatggtga atggcaatga tgcgtaatac
    10321 atatccttat tccaaattcg attagtagca ggatagctgc cccaattgct gccgacgacc
    10381 tgtccctgtc gattcatacc gaaactagaa aagctttgat aaagtgcacg acgatagaga
    10441 tggacaactc tatcgtttgg cattgacagc tgcccaaata gctgagcaaa atagttcaat
    10501 gtttccttca gccatttttc gatatcagat tcctgaaaag tcattacttc ttcaaaagca
    10561 tttgggtcca caaaagcaat ggcgaagctt gccacttcct gttgtgcgat cgtgtcctta
    10621 tttccttttt gagaaatcaa cacattttgc tgatccgaat acttctcttg atacgaaggc
    10681 acatctttca ctgaaacttg aaggctttcg tgtgtttcat tcacaatgta aacctgttga
    10741 acaagcatac ttaaacgctt attagccagt atgggagcaa aggatactac aatgacctta
    10801 aacgtcgaat aatgatgaat atatctaggc aaacagtctt gaatcacatc gacttcaata
    10861 cgatgatccg attctgacaa atggtagaca atcccgttta cttcaacctt taaggataac
    10921 gaattggttt gagagagctg tttattgacc caaacacctg gtttttcctc agttagtaaa
    10981 ttttctcgat aaaaggtcaa cgtttgaatc gtcccgcaaa catcaaggtt tgctaatgtc
    11041 ttttgattac ttacatcgaa ggtcaatccc tttacatcag gaatattccg atagtagctg
    11101 tattcgtttg aagtagtcac atttccgtcg tttaactcag cattaaaaaa tgggtgtttg
    11161 ggtgaataaa ttacttcatt aatagtcatc ttttccctcc ttgctaaaaa aactgcagcc
    11221 tagtagctgc agcttcctac tatgcgattc caagtaatga caataaaatt cccatgacga
    11281 ccattccaaa aataattttg atgacgccga cttttttatc tagtaatttg aaacagctca
    11341 atgttaccaa taacggtaca attcctttaa aaatactatc gaggatttct tggacattca
    11401 ttagttcttc gcccttcatt gaaaagctca aaacggtatt gaatttgacc atactgatcg
    11461 tcattgcacc taccatgatc agacccaaga tactagcagc ttttgtcaga atttcaatta
    11521 acccgttcgc atacagcttt tcaatatatt tagagcctaa tgaatagcct aaaacgccgc
    11581 catagtatcg catcaagtaa ttaggtatat tgaacataac taaaaagata attggtgcca
    11641 aaatatttcc ggcattggct aagttgatcg ctagtcccgc ggtaacgaca cgccaaactc
    11701 cccagaacaa tgaatcgcca attccagcca atggtcccat caaactcgtt ttgatcgcgt
    11761 tgatactttc cacgtcaaaa ccagcttttt cagaattttc cttctccatc gatgccgcaa
    11821 tccccatgac aaaggacgcg caaggaatgg tcgtcgaaaa atactgtgta tgacgttcca
    11881 gcgccgcagc tcgatcttct tcacttttgt agaaatgatt aatgaagggc atcatagaat
    11941 aggcgaaacc accgccgccc atcgtcaccg gattcaccga agcatacata gtcatcgagc
    12001 gccaaaacat cttccgaacc aattttttct catctttaga aattccatca gctaatttca
    12061 ttgaaagaaa tcctcctctt cttggtcaag cgttgcattt acagcagcat cgctttgaac
    12121 tgcatgaaca gatatatttt ttagttgtag atctctttgg gctataacaa ttgcaataat
    12181 cgttccaact gcggcaattg caatcaatgg taactcgaga tacgccataa caacggcccc
    12241 aaagaaaaac cacacagcaa tatttttact ccaaagcatc cgtaacagca tcgccatccc
    12301 aactgccggc agcagatttc cagcgactgt taatccgttc atgatgacct ctggaatatt
    12361 atccaagacg cttttgacaa catctgctcc aaataaaacg gcaaagaatg gaataagagc
    12421 ataaagcgca tagtggacaa accacataaa gaagtgcaga ttgatgattc ctttttgatc
    12481 accagatttt gcaaatttga aaaatttagc agccatcggt ccacatacaa aagaaaaaat
    12541 catattcatt aactgtaatc ctaatactgc tagtggaaag acaatgggaa taatcgcatc
    12601 cacgtttcct cccattttga ttgcgaacgc tgtagccagc ccagcagcca aagaaggctc
    12661 cgccgtacta gagattccga tattgacgac acccataaag atggcttcta gtgacgcccc
    12721 gacaatcaac cccgtctgca aatcccccat caacgctcct gctaacggag caacaacaat
    12781 cggacgactc agcatggaca tcccgaacat ttcatgtcca gcaactccaa taaaaacggc
    12841 caaagcgact acaaatgcat catacataat ttttctcctt cctttttcta aaaatcactc
    12901 aaaatagaga tagctgaacg tttttccatc gccggtgtag gctgaaaaac ggtatctgga
    12961 taaagttcaa ctaattcttt taagtcttga atttctgacg tcgttaacat cacttccttt
    13021 gataaggttt tcttatcttc cgatggcggt gtcattttcc cagcattccc cacgttcatt
    13081 aattcgattt ccgttgggaa agctttcgca acttttaccg catctttgac attagggact
    13141 aaaaccatca agcgcatgtc cttcgcccgc ggatctttta acaaatgaat cgcgtcatca
    13201 actgttttaa taatgacttt gacattcgat ggtgcagcca tcttcaatgt catcttttga
    13261 atatcgttgg tagccgcctc atcgcttgct actactaacc cggttaaatt tagactcttt
    13321 gtccaagtca tcgctacttg tccatgaatt aatcgttcat caattcgcac tgctttaatc
    13381 atttttcttc ctcctaaaaa aaatcttcct cttcatttac tacatgtacc tcatcaagaa
    13441 tggtcatctt taattcctgt tggcatttat ttaccagttc ctgaatatcc tcctttgtta
    13501 attccttggt tgccaatact atttcgagca gaattggcag attaaagcca gacaaaatag
    13561 ttacagcaat ctctttctcc aaaaaggttt tggtaatctt ctgattgaca cttccgccaa
    13621 ataaatcggt aaaaacaaaa atctgatcct gctcgttcac ctggtttaca aatacattca
    13681 actcctgttc aaaatcacac tcatccacat aagcattaat caccgtaatc tcttgaacct
    13741 tccccgtcag taattgaata ctgctaagaa agcctgaagc taagtgaccg tgagtcgcta
    13801 ttagaatttt cttcatatgg ttaattcctt tctttctgtt cacttttata taagcaattc
    13861 ctgtgccaac ttttaaaaac attggtttaa tcacgttaat tcacattaaa aaaagtgtct
    13921 aacctaaaaa aaacagatta gacacttttt tagacacttt atttttgaat atacggtcct
    13981 aataattcat agagcagcga aagctcataa gcattgactt taaaattata tttcatctcc
    14041 attgattgaa aaatacttct agaaacataa taaaattcat cttcatctgg tttcaaatca
    14101 taattcggtt cttcagattt ttctgtccga gccaagaata aacgttccat catcaatgcc
    14161 gtatgcatat agagatttag ttttacacgg ccatttaaag tgaaatgata gtaattttca
    14221 tatttagaaa tgactgtttc cacttcactc atcacgatcg ttgggttcag aaagttcaaa
    14281 cggtccgcaa ttccttccaa cgaaaagaat tttactagct cctgaatcaa gcggttaaat
    14341 tctgccggct tcatttcagg actcaaaata tgctccaaat tggctgctcc atcaccgtct
    14401 aagatgtcat aaacattaat attaggaatt gaaaaggaac gtggaagatc cgaagtcgtg
    14461 atgaccaatt ttgtcttgtc aaaataagtt tcatcatttt ggtcgattaa ttcacgtagt
    14521 tctctgtagt ccttcgtgaa aacttcgatg gattcatccg ataaatgatg acgaaaaaca
    14581 tctttcaatt tgtccgaaat ccccaaaccc gacatacagg aaatgataat gttgctactt
    14641 tgagaaaagc cttcaaagta ttgaacattg attgaatact tgtctgctgc atcctccgca
    14701 atctgtttaa atggcgcatt catcgtcatc ttcaagccaa tatcaagtgc aatggaagtc
    14761 gtcaaattat tcagaagaag taactcccct tttaaatcgt tcttgatctg tgtgtaaatt
    14821 tgatttaaag agcccatatc tacgatcagc actagactat ctgtattcac ttgccgtttc
    14881 acgaaattcc ttgtcgattc gacaatctct gacacattac tctctactgg catatccaac
    14941 gcttcaaaaa cataattgcc gcataattga ttcactactg cttgaatgct gctagccgta
    15001 ctatctccgt gagcaagcaa caggcccttc agctcgatgg attcatctac ataatcagat
    15061 aaagtcacga caataagcag tcttagaaag ttctcgtcct tttctgagag cggtggtaaa
    15121 tgctccaaga actgattaca taagtaagtc gtccgaggta gatttgcagc taatgtacga
    15181 tttatcccgg ttaagtctgt cttatagctt ggggaaatga cataggatct gctaataatt
    15241 tctgcaacag gtccactcgt cgtcaatccg tacgtttttc ctaaaacgga tacccagacc
    15301 tttctaaaca tctgaatcat caattttcta ctcattgata aaaaagaatc cttatcaatg
    15361 tgatgcacca aatgctgtac ttcattcttt atcgaagaaa aattttcatt gaaattacct
    15421 tcatttatca gctgagtaat tttttccaaa atcgaatcat aatcaaacgg tttgattcga
    15481 tccgttttta tcttttgatt tttctttatc aataaactag caatcggcaa gctttctact
    15541 tcggattcca gcatatttaa ctgaatcaag atctcatttt tcccaatcgt taatggttct
    15601 tcttgtgttc gactatacac atccgcacaa ctgattttaa tgatattctt cagcttacca
    15661 atattcccac taaagggatg agataacatt aaagacaagg cttctcttga aacaataata
    15721 tctttttgta aaacatccgc ttcattttga aaaaataatt gaatcagctc taatcgttct
    15781 cgaatggggc gatcttcaaa agttggcaac ataacactaa tttgaatacg ccgatcaaag
    15841 gtgtctaata aataattttc acctttttcc gtcgtggcga aaataaaacg aaccttagca
    15901 gaatgccaat ttacattttc accgactgga cgatagtttc cagtatcaat aaatagaaag
    15961 agcttttctt gattttcttt cgataggcga tggacctcat cgagaaaaag atagccgttg
    16021 ttggccgttg ccaataaacc atcggtatcc ttttcagccc ccgtaaaggc ccccttcttg
    16081 tatccaaaca gtgttgccga aagcagttcg ggattgtccg cataatcggc acagtttaag
    16141 atagcaaatg gtgcatcttt ttcaataatt tgctcatgga tagcgtattc aaaaattttt
    16201 gtggctaaaa aactttttcc aacacccgtg gctccattta ttaatacact gagtccgtta
    16261 ggcggatatt tgacagcggc tatacatttt tgaatgacct ctctcagact tccgtcatga
    16321 ccaactacag aatgaaaggc ttcgtttatt tgctccgtat tatctacaac cgcatattca
    16381 tctaaaggct tccacaaaac aggctttccc ggtaatttct cgaccttttt atcttccact
    16441 aatctcgtca aataatggct ggcattctga cgagagatac ctagattctt cgaaattttc
    16501 tcggcagtga cagaagacat attccctgtt agtcgtatca gctcatcaaa aactcgatct
    16561 ttagcgctct ttttcatttt ttcctccagt ttaatgtgtc taaaagcata ataaactatc
    16621 ggctgcaata tgtctattct atatttgtat tccaattttt actttgaaac acaaatagtc
    16681 gaatatttgc ctcagatatc tgacaaaata atttatctac caatttagtt tttatctaat
    16741 atgattttta tgttttttca tagctacaaa tattgaactg gattcatata ttagttttat
    16801 taatagatta cagaagggtt aagtatattt gcatagtttc caattacttt atccttctgt
    16861 aactttttca atcttagatt tactagcccg tctcgggccc tattttacaa tggttttgtc
    16921 cacttttctc tggtagaaaa acgtggtaga aaaaataaaa taacacaaaa aaagcggcgt
    16981 ttcatccgct tttggtagaa gattggaaaa ctcagataga aaaaggacga tttttagctc
    17041 tttagaacgt tgataagtcc ccattcttac tgagttttgc cattatctcc tatacatctt
    17101 gaattctaag aataggtcat tatagatgcc taggtatttc gatcctagat ctttgtagac
    17161 ttcaagatgg gagatcgtgt catcagatgg atagaattgt tcgtccgacg aaatgtcttt
    17221 tggcaataac gcttttgctt cttcatttgg tgtagaataa ccaatatact ctgcattttg
    17281 tgccgcattt tccggttcta gcataaagtt gatgaaatca taggcacctt ctttattttt
    17341 cacggttttt ggcataacga tattatcaaa ccaaagattg gatccttctg gtgggatcac
    17401 ataatgtaaa tgttcatttt cccacatcat atcggcagct tcgccagaaa atgtcactgc
    17461 cacggaggct tcttcattga tcatatacat tttgatctca tctgccacga ttgctttgac
    17521 atttggtgtt aaatgattca atttatttgc tgcttctgtc agctgtgcca tattcttact
    17581 attcaaagaa tagcctaaac tattcaaaga aagccccata acttctcgtg caccgtcaat
    17641 cagcatcaaa ctgtctttta attccggctt ccacaaatca tcccaatgct taatttgatt
    17701 tgcatcaaag aatttatcgt tatatacgat ccctaaagtt ccccaaaaat atggaatcga
    17761 atactgatta tctggatcaa aatccaagtc taaaaatcgt ggatcaatat tatttaatcc
    17821 tttgatcttc gaatgatcta atggaagtac tagtttttct ttgatcattt tttggatcat
    17881 atattcactt ggtatagcga tgtcgtagtt tgtcccacct tgctggattt ttgtgaacat
    17941 cgcttcatta gaatcaaatg tttcataatt cactttgtat ccatattctt tttcaaattt
    18001 cgtgatcaaa ctaggatcga tataatctcc ccagttatag atggtaagta cctttgctcc
    18061 actcatgcca cttgtttttt caagttgacg aacaccaagc agcagcaccg caataatgat
    18121 gagaatacct aaaaacagag attgtaattt tttcatcgca gccgtgccac cccctcgcgt
    18181 actcttctgt ttttcttcag ccgttttgga cggttttctt tactaataaa gtagtatcca
    18241 atgaccaata tcatggagaa caagaaaact aacgcactta gcgcattgat ttctaaactg
    18301 attccttgtc ttgcacgaga atagatctct actgagagcg tcgtaaagcc atttcctgtg
    18361 acgaaaaatg taaccgcaaa atcatcaaga gaataggtaa atgccataaa atatccagct
    18421 atgattcctg gagaaagata aggcaaaatg atatttttga ctacttggaa attattagca
    18481 ccaaggtctc tagccgcatc gaccattgaa tcgttcattt cctgcaattt tggcaagacc
    18541 atcaagacga cgattggaat gctgaaagca atatgggaaa gcaatacact ctgaaaacct
    18601 aatccgaatc ctagtagtgt aaagaaaatc aagaaactag caccgataat aacatcagga
    18661 gagactaata agatgttatt catgctcaac aacgctgtcc gtgcacgtcg ttttttcgtg
    18721 taatagattc ccatagcccc aaatgtcccg atgatcgtgg cgatcaatgc agataagaaa
    18781 gccagcatga acgtattcaa tacgataatg atcaaacgtg tatcttcaaa aacagcttca
    18841 taattttccc aagtaaatcc tgtaaagctg ttcatcgttc ctccttcatt gaaggaataa
    18901 aaaatcagat agaagatcgg tgcatataag aataaaaaga cgatccctaa ataaagatac
    18961 gaccatttaa attttttcat ttatgagcga cctccttttt tcttctcgcc tgtcaggagc
    19021 atcacgatga acatagcaat gattaaaatc acaccgattg tagaacccat cccccagttt
    19081 tgtgtaacca agaaatgctg ttcgatagcc gttcctaaag tgatcacccg atttccgcca
    19141 atcagacgag tcagcatgaa taaagaaaga gaaggaataa atactgcttg gacaccactt
    19201 ttcacaccat ttaatgataa cggaaaaatc actcgtcgga aggtctcaaa gctattcgcg
    19261 cctaaatctc tactagcact gatcaaagaa ggattcatct cttccaatgc attgaaaatt
    19321 ggcataatca taaatggaat ctcgatatac gttgccacga acagaaaact gaagtctgtg
    19381 aataatatct gtttcggccc gatcccgata aaatcaaaga aatgattcac gctgccgtgc
    19441 acactgaaaa tcccaataaa tgcgtaagct ttaagcagca gattcaccca tgtaggcaaa
    19501 ataatcagca tcagccataa ttgcttgtgc ttcagttttg ttaaaaaata agcagtcggg
    19561 taactgatga tcagcgtgaa aaacgtgatc aaaaatgcat accatacaga attgatcgtc
    19621 atagaaagcg atgtccccga cgtaaaataa gatagataat tattcagcgt gaattgccca
    19681 ttcatatcaa aaaaagattg ataaatgatc attaatacag gcgcgatcac gaataaaccg
    19741 agccacaaaa tataagggac ggaatagatc ctgcgcattg ttttcattct tgtcccccct
    19801 attcttcgta gctgtcaaga cgtgcatcga attcttcttc agactcgttg aaacgcatga
    19861 catggatatc ttctggctca aaggccaatc ctactttgct tccttcttta gcttttttcg
    19921 ttgaatggac catccattca ttttgctgtt catcataaca gatgatttca taatggacac
    19981 cacgaaacag ctgagtatcg accgttacga ctagttttcc tttatctggt gtcgtgatcg
    20041 tcaaatcctc tgggcgtaaa acaacttcaa ctggttcatt tagacgcatc ccgccatcga
    20101 cacattcaaa ttgcttacca acaaactcaa ctagattatc ttcgatcatt acaccgtcca
    20161 cgatattgct ctccccaaca aaatcagcaa cgaaatgatt gattggctca tcataaatat
    20221 ctacgggtgt accactttgg acgattttcc ctttattcat gacaaaaatc tcatcactca
    20281 ttgccaacgc ttcttcttgg tcatgagtaa caaaaataaa cgtgattcct aatcgttgtt
    20341 gcagatcccg cagttcatac tgcatatctg tacgtagttt caaatcaagc gccgataacg
    20401 gttcatctaa tagcaatact ttcggttcat ttacaattgc tcgtgcaatc gctacacgct
    20461 gtctttgacc accagacatt tcactaatct cccgtttttc gtatccagga agctggacca
    20521 tacgcaaagc atcttttacc ttcttttcga tatctgattt ggacattttc ttgatcttca
    20581 atccaaaagc aacgttatca aaaacattca tatgaggaaa aagtgcataa tcttggaaga
    20641 ctgtatttac ttgtcgctta ttagctggca aatcattcaa ccgtttccct tcaaaataga
    20701 tgtccccttc tgtagcttcg gtgaatccag ctataatacg taggatcgtt gttttaccac
    20761 agccggaagg accaagcagt gtataaaatt ttccttgttc gatctcaaaa cttacttttt
    20821 ttaatactgt ttcatcatca tagcgtttca ctacttgatc aaatgaaatg attggtttcc
    20881 ccacgttttt accccctata ttacaaatat gattgcgttg caacaatcaa tacttttgtt
    20941 cgttttttga gatgattcct taattgatgt tgttttgtcg cttgataata gatcgactgt
    21001 cctgcttttg ccacatagac cgtctctcct aagcttaact ctaattcccc ttctaataca
    21061 aaaataaacg tttcagataa tgaaggttca aacgtcttat attctcctgc accttcaaaa
    21121 gtcagcaaga caggctccat ttctttttca ttcgaatcag ccacgagcca ttccaattca
    21181 tacccgtttt cttcatcgaa ataaaccgta tgatcttctt ttgaataaac cacttgcaga
    21241 ttcgctgctt cttgatgaaa aaattcttct ggagtcacac ctaagacttc aagaatagaa
    21301 aagaatgttt ccattgatgg tgaacttaaa tctcgttcca actgggaaat ataccctttt
    21361 gacaaatctg tgcgttcgcc tagttcttct tgtgtcaaat tcttttggat gcgcaaattt
    21421 cttaacttct caccaatttc cataatttcc tccgaatcga agttttctaa tagtaaactt
    21481 cctgtttact accactcgta ttagtatacg aaatttattg aaaaaggcaa ccctttgtaa
    21541 aatttttttt gctgaatatt tctttatctt ttggaataaa ttctagttgt ttgattcttt
    21601 atttttcacc taatttttgt ctaaatttac ggaagaacaa gaataaaaga gtaggcttta
    21661 tggtatgata aaagaaaatt ttaaaaggag tgtctcacga atgaacgctt ttcgatcttt
    21721 tcaggtaata aaggaacctg ttttccatac agcaatcagt gatctgccat ttactgagtt
    21781 ggctgaaaat gaagtcttgg taaaaattgc ctattctgat gtcaattata aagatgcatt
    21841 ggcaatgagc gagtctggtc aggtgatacg aacatatccg atgactccag ggattgattt
    21901 atccggaact gtcgtccaaa gtaacaatcc acgtttttca aaagaagatc ttgtacttgc
    21961 tactggtttt gggcttggcg tcacccatcc aggcggttat agccaatatc aaaaagtacc
    22021 aggagactgg ttagttcctc taccaaaaaa tatgacgctg cgtcaagcga tgatccttgg
    22081 tacagcaggg tttactgcta tgttgtgtgt gaacgcttta atccgtcaag gtatgacctc
    22141 cgataaaaaa gttgtcgtta ctggtgcttc tggcggtgta ggcagtacag cgatagccct
    22201 gttacataaa ctaggattcc agtcaatcat tgccttttcc agaaaagaag agtctgtcac
    22261 atggctaaaa agtctaggtg ctttgcaagt cgtacgacct gatgaatttc tgccagagac
    22321 aacaaaagct ttaggaaaac agcaaatcga ctatgtcatc gacacagtag gtggcgagca
    22381 gctaagcagt cttcttccat tgatctctta taacggtgca gtagctttat gtggcaatgc
    22441 tgggggaatc aaactaaacg cgactgtctt gccttttatt ctgcgaaaca tccagttgat
    22501 tggaattgat tctgtcaatg taccaataga tcaacgtctt tctttatggc aacagatggc
    22561 ggatttgcag attgcagatg aactggtcgt ccaagagatt actctggatc aattgcctga
    22621 aacagcatct aaactacttg ctggaacaca ccaaggaaga acactagtaa atgtaggtga
    22681 ccataaatga agattctaat cacagctgga ggaacgactg aaaaaatcga tcaagtacgt
    22741 gctattacaa atcattcgac aggacgatta gggcaagcat tagctgatta tttagctgcc
    22801 aatccggata ccacaatcga ttacgtgact acgaaacaag cactgaaacc gaaaagacac
    22861 tccaatataa cgatttatac gatcgaatct gcactggact tatttttaca attagaagaa
    22921 ctaacgaaaa aagaacacta cgatgcgatt atccacagta tggcagtcag tgattttact
    22981 cctgctttta gtttttcaga agaacagctg gcaaaaaacc tacccacttc ttcaacgcaa
    23041 gaagaactgg acaattggtt tgcggaaaat gaacagacag ataccactgt ttcaaagatc
    23101 tcttctaaca ccgagcatct tgtgctcgtt ttgaagaaaa caccaaaaat catttcttat
    23161 ctacgtgaat ggcagccaaa agcaaaaatc attggtttca aactattagt agatgtacca
    23221 aaggaatctc ttctggcagt cgcaaaaaat agtctgataa ataacaaaac tgattttatt
    23281 ttcgcaaatg atttgacgga aatccatggc gagacacacc acggctatct cttatctaaa
    23341 gatggaacag tggaagaagc tcaaagtaaa tctgagattg ctgcattgat tactgagaaa
    23401 attagactgg aggaatcaaa atgaaaaaga tcttactagg cgttactgga agtatttctg
    23461 cttacaaaag cgctgatctt acaagtcaat tcgtcaaatt aggtgcccag gtagatgtga
    23521 ttatgtctaa aagcagcaca cattttatca cgccattaac cttgcaatct ctgtcgaagc
    23581 gcgcagtcca tacagacgtc atgcaagaat caaatccgca ggtaatcaat catatcgaac
    23641 tagcaaaaca agctgacttg tttctcatcg cgcctgctac agcaaacatt atcggcaagc
    23701 tagcaaacgg cattgcagac gatcttcttt caacagtcgc aatggcgctt ccagtgggaa
    23761 caccaaaatt gattgcccct gccatgaaca cgaatatgta tcaaaacccg atcactcagc
    23821 gtaatctgga aacattgaga tctgtcggct atcaggaaat tgaaccaaga gaatctcttt
    23881 tagcttgtgg agattttgga aaaggtgcct tagctgatat tcagacgatc atcgaacagg
    23941 tcatgctgac tcttaatgaa agaaatgctt agaaaaaagg agtacttatg aaaaatacaa
    24001 aaaactttac attaactgcg atgtttttag ctattttgat tttattagct gttacgcctt
    24061 taggttttat ccctatcggt ccaatcaatg caacaaccat gcatattcct gtaatcattg
    24121 cttcgatcgt tttaggacca agactaggtg cttttcttgg cggtacattt ggactgatca
    24181 gcatgatccg tagcacagtt atccaaacac ctttgtcttt tgtcttttct ccgtttatcc
    24241 cagtcatcgg aacagaacat ggaagctgga aagccttgct gatcgcgttt attcctcgca
    24301 tcttgattgg ggtggttcct tatttcgttt ataaaggtct gcgcaaacta atgaaacaaa
    24361 aagcagattc cgtttcttta ttcttagctg gactttccgg ttcattgacc aatacgattt
    24421 tagtgatgaa tatgatctac tttttattcc agcaagatta tgccaaagtc atcggaacaa
    24481 atttaaatgc tgtttattca gctattctag cggttatttt tacaagtggt atacctgaag
    24541 gaatcgtcgc aggtcttgcg actgcagcag tatgcaatgt cttgttaaga tacttcaagc
    24601 acccttctct tactaactga tagtcatcgt agccgatctc tgattttttt ctcttttggt
    24661 gttactattg aatggaaaga tttgacgtcg aaaggatgat ccaaatgaaa atttttgttg
    24721 taggtgcaaa cggacaaatt ggccgacacc tgataaaaga tttagctcca agttcccatg
    24781 aaatttttgc aggggtgaga gatgttgctt cccaaacatt agtaaaaaaa gagaatgttt
    24841 cgtatgtctc ttttgattta acttggtccg tggaaaaaat gaccgaagca ttcaaaggca
    24901 tcgatgtatt gatttttgct gccggctctc aaggaaagaa tcttctgcaa gtagacttgg
    24961 atggcgcaat caaaacagtg atcgcagctg aaaatgcgca tgtctctcgc tatctgatgg
    25021 tcagtgctgt ttatgcagat gaaccagcaa aatggcctga gtccatgaca gattattata
    25081 ttactaaaca ttatgcagat gaatggctga aacgaactaa cttagatttt gtcattcttc
    25141 aaccagtcac attgactaac gatgaagaag ttacttccat tcaattaact aagcctaatg
    25201 agaaggcatc aaaaacgatc actcgctcta cagttgctgc tgtacttgcc gctctagtgg
    25261 aagaaacgga tatttctcgt acgactctag tactttctga aggtagcaaa gagttgaata
    25321 cagcattcca agaatgggca aaggaggaat agatccatgc gtgccatttc aatcaagcat
    25381 cctggttctg tagatgtatt agaacaaatt gaagtgcctg ttcctaaacc aaaacaaggc
    25441 gaattactga tcaaagtcca tacagcagct gtcaatcgaa cagatattat gaaaagagaa
    25501 tcagtctctt tgaaacctcc ctaccctatt ttgggagtcg aagtagctgg agaggtagtt
    25561 gagaataaaa gtgatatctc cacttttact cctgggacaa aagtatacgg attagtcaat
    25621 ctaggtggtt atgccgaata tgctgtgatg cctgccgatc gtgcaatcct tctccctgat
    25681 acgctagact atgtttctgc tgctggaatc tcagaagttt ttttgactgc ttatcaaaca
    25741 ctttactggc ttggaaaatt acaagaaggc gaaactgtct tgatccatgc aggagcaagt
    25801 ggtgtgggaa cagcagcgat ccaattagct agacagcttt ctcacgcgaa aatcatcgtt
    25861 actgcaggat cagaagaaaa actcgccttt tgtaaagaac ttggtgcaga tgaattgatc
    25921 aactataaaa aacaagactt tcaagaagag gtacgaaaaa tcactgaagg tcggggagtc
    25981 gatgttattt tggatttcat cggcgcttct tactgggaaa agaatttagc ttctatagcc
    26041 gttgatggac gttgggtctt gattggtatg ctaggtggga ccatcgtgcc tgagatagac
    26101 cttggtgtat tgattgggaa acgtgtccaa ctgcttggta cattattgac acctagaagt
    26161 gatcagtata aagcagagct cgcacaaact tttatgcaaa aagctgggcc ttttctagaa
    26221 aatggcaaga ttcggccaat cattgaccgt acattccaat tcagcgcagt caaacaagcg
    26281 catgaatata tggaagcaaa caaaaacatc ggaaaaatca ttttgaagat aactgaataa
    26341 aatcatgctg atcaaaaaag aggctgggac agaagcgttt aactccaaga aataagaaga
    26401 aattcacgaa aattgctttt caaatttttg tgaatttcag cttatttccg aaggaatttc
    26461 ttctgcttcc gccgtttata cgtgtttaga gcgtgagaca aaagtgttct ttacttttgt
    26521 cccacgctct ttttccgaat aaacggtgtt caaaagcttg catctgcggt aataagtcca
    26581 accaagttaa aaacataaga agctgttttt acttggctgt tcttattact tgatgcaggg
    26641 cagctttttc acaacctctt cactaaacag tgttcaatca gctgaccctc ggtattagct
    26701 caaaacgctg atttcacaac ctctttttat ttacgttcta tttcattcat tttccgaagc
    26761 aaatcgagct gcttgtatgc ccgcttgtcg cccaaaaata atgatctccg caactgaatt
    26821 tccaccgatc cggttgtttc catgtaagcc acctgtgact tcaccagcag catataaccc
    26881 cctaattggc tggttttctt tatctaatac ttcagtgttc gtattgattt tcacaccgcc
    26941 catcgtgtaa tggattcctg gtgcgatttt gatcgcataa taattcggag acgataagtc
    27001 atgttccatg gctgtggcac ggttgaattg agcatctttt ttctccgcaa catccgtatt
    27061 ccatccatca actgtttttg ctagtgtttc ttttggtaaa tcgatttttt ctgctaattc
    27121 ttccattgtc tttccagttg tgacatatcc tttttggtca taaaattcaa tagctgtggc
    27181 acgatcacgc acgccttggt caaaaatcaa ataagctgat ttttcaggca atgctgtaat
    27241 tgctgcagat actttatccc ttgtatccat ttcattgaca aatcttttcc cctcttgatc
    27301 gaccaagatt gctccttctc cgcgaacaac ctcaccaatc aagaccccct catcctgctg
    27361 cacagttgga tgaatttgta ttttatccat atcaacggtt tgtccaccta atttttcaat
    27421 catggtgata ccatctccag ttgatccttc ttgatttgtc gtaatataat cagctaaatc
    27481 gggacgatat ttttcaataa attctttgct ggcaccaaaa ccgcctgtgg taactacgat
    27541 tgcttttccg gtgacctctt ttggttcttc tccttgaaca tgtacagtca cttcattgac
    27601 cgtttcccca tttttcttaa tgtctgtcac atctgcgttg acaaaaatag ggatttcccg
    27661 ctcatggacg ttattcaata acccctccac taagtatcca ccaatagccg agccatcaga
    27721 cggacgatgt gtcctctttt cactcatccc tccagtgatc gttaagttgt ccagtttgat
    27781 accgttttga tctagccaat cgaccgcatc agcagagtga tcgacaaagt atcgaagcat
    27841 ttctttatca ttcgttcctc caccaccttt tagcgtttct tcatagaagg catcattcga
    27901 gtctttgatt ccttcttctt tttgaaattt tgtttctgaa gcattcatac cgcttgatga
    27961 tttagatgtg tttcctccgg caacaggcat cttttccaaa attactggat tcaacccagc
    28021 atcttttgct tcgatagctg ctgccatccc tgcaccacca gctccaataa tcacgacatc
    28081 ataagattct ttcatttctt ttggatctgt atatacttgt tcagaagcgc ctgatgatac
    28141 ttcggcagat tccttcgtac tagaacttgt ctgcgctgta tttttctgat ctgcgccgca
    28201 tgcgctcata gcaagaagtg caacggctgt taataaacca gcaactaatt ttttcatttg
    28261 tatccccctt ttctccttat actatattaa gtgatttttt tcacaatatc aactctgttt
    28321 ttctttaagt catatagctt tggtaaacac acgcttctta gtataattaa ggatatacat
    28381 gaaggagtta ttttatgaat catttgaaaa ccttttttac gaacagtaca aaaactgcag
    28441 gtagaatcac aaacggaatc tatattttat tacgtatcat cgtcgttatt atgctagtgg
    28501 atcaggtctg gaaccaacac tggggaaata caatgctttt attactgaca ttaattttat
    28561 ttgaaatccc ttattttctg gaaaagatat taaagataca gattccaaat atgctagaaa
    28621 tcattttgtt atcttttatt tttagttcaa cagttttagg agagttaagt gatttttatg
    28681 gctatttttc aatgtgggat acttttctac atgcattcag cggattttta gctgggggtg
    28741 tcggcttttc ccttgtttat ttgctcaata aaaatacaaa aaccatgaac ttgactcctt
    28801 tattactagc agttgtttcc ttctgttttt cgatgacagt tggtgttatg tgggagtttg
    28861 tggaattttc agcagataaa ttactgcaat tcgatatgca aaaagatacg atcatccagc
    28921 aaatcaatag tgtggagtta agtaaagacg gaaacactgt ctatcatgtt ccagatatca
    28981 ctcggacaat cattgaaagt caaaatgcag atggtaaaac agataaaaca atcatccaaa
    29041 atggttactt agacgtggga atcatggata ctatgaagga tttatttgtt aattttattg
    29101 gagcagttgt tttcagtgta tttggttacc tctatagtcg aaacgattac caaaaattta
    29161 cgttcatcaa gaattttatt cctaaaaaaa tcaaacgata aaacatgcta aaaaacaaga
    29221 gaaggggcag tgacaatact tttgtcactg ccccttcttt tttgaatgta tggcatgcca
    29281 ttagttatcc gatagtatta actcaaaaaa gtaagatatg aggaatgact atttcgtttt
    29341 ttatcccaat actgaggact tatttcacca tttcgttatt tatctaattt acttaaaacc
    29401 tgcataactt tttcataatc tggattaggt gtgccgtcta gattttcagc aataaaagta
    29461 aaacccattt ttttataaag agcaatcgcc tgatggctcc atgtctgtgt gtgaagatag
    29521 attggtccgt ccgtatggag ggtaggaaat tcttgcaaga ctctggcagt caatgctttt
    29581 gcgagccctt ttccttggta atctggtttc actgctaacc aatgaaaaac cggatacact
    29641 tgctctcttg atttttttcg ccaagcggta caggttgcta ctttttctcc tttttttgtc
    29701 tctacaaaaa acatccttct ttcaagttct tcaggataag gagcaaagtt ttgttgaaaa
    29761 tactcaagtg cttcatctgt cgtttgaaat tccccaacgg aagtctcaat ctccgcccaa
    29821 gcagattcat cttctttttg ataaaatcga aattcaaaac cttccgctaa aggcgtgatt
    29881 ggaacatttt gttgaagtgg tcttgtcatc cagatttctg cgtaaggtaa cgttttatct
    29941 aacatttttc tatccctcct cgtctccatt atgccaaata acatatgact cagctactta
    30001 tttgactata acagatagag atataaatca gaaccagtca tctgcgtcaa attcatttcg
    30061 attagcgtat acccatgttc ctgccatacc tcgcatgaaa tctcctaaag cagaagaagg
    30121 aatacctcca ccaggtgcgg gtgttcccgg actaggaagt ggtacttgcg gctgcagatg
    30181 ctcatcggtg gaatcaatag ttgacaagcg ttttttcttc gtttccttct ggtcatctga
    30241 ttccttctga tcttccgact gtttagcaac aaattctttt tctgattgtt gttttatttt
    30301 aggctctaaa atttcatttt ccaatccaga aacttgtggg gccaaatgag cttcttgcct
    30361 tatcgtttta ttagattctg agatttttct agatattctt gctaactcta ggcttcttgt
    30421 ttgttttact ttccctgttg gagaaactgc atgagccatt tgttgttttt tttctgacaa
    30481 gctttcttct tgtctttttt gttctttttg atctatctgt ttgtttaatg gtaaaacatg
    30541 taatagtgac tgagcatgga gttcttggag tgaatacggg tcatgataac tatacataat
    30601 cgtaaaatca cctgtttgtt tggtcaaata accatcctcc aatggtactt cattgattgt
    30661 aaccgataca tcctttaacg gtacgggttt acctaaggaa tttgttgctg attggatcaa
    30721 ctcttctttg tttatttttt cgtttggatg aacaataaga tcatgacctt ctaatgaacg
    30781 attgtctggt atataaacat aagtaaaggt aatttcccct cctgattgct tcctattatt
    30841 catcagttct gagtgaagta cttcaaggat ctccgaccag tgactttttc tgtctaatcc
    30901 gtttgcttgc atccaatcag aaatagaagt gactttccca ttttgttcat aagtcgataa
    30961 atctatattt ggcactcgat cagaaaattc agcaggtagg cgcaaatcag gaatacgatt
    31021 tacactactc atatgtgttt ctgcttgaag ttctttattt gtttgactat ctataaaatg
    31081 agtgatgaca gtcgatgaag cagcagatgc ttctacataa actacagctg ttgtttctgc
    31141 cacatttgat gttttcgagt ctatataagt taatacaacg ggatattctc ccggagttgt
    31201 agtatctact gtcccgttca ttttgatttc ttctttattt cctgaagttc catcgctttt
    31261 tgttacatat tcaacaagat ctttaggggc gtaactctct cctgttctta agtgaagatc
    31321 ttttcctttg atagctgttt gatcagcacg aacatggatc acagcagatg cagtcattgt
    31381 ttttaaagca attggatcaa aataggacaa ggaaatagta gatgttcctg tattagtcgt
    31441 atccacgata ttcccattgt ttgaaattac tttggacata tctccttgtg ttccatctgc
    31501 gttcttcagc ctttctacca gatcagatat cgaaactttt gtccctgcca gaacatcgat
    31561 tttctttctt tcaaactgtg aataatcttt ttcatataca taagaaactt gtgcgcttcc
    31621 accgtccttt atatctgtca aagcatgatt caaaatatca gtgatctgtt ttaactgatc
    31681 accttttgta ggatcagtca tatcggaaaa gatagaaagc ggcacactgc ttccggtttc
    31741 cgatgtccat aatgttttgt taggaattaa ccagtagtgg tttatcgttg gaggataact
    31801 gactttatta taggaagtca atgcaggaag tagctgtttt ccatttgcat cagtgaaagt
    31861 atgagtaata gtgatagggg aatcagtggt ctcagaaaca gaggtacgta cgaccttgat
    31921 ggtttgtgtc gttgcctgaa cgggtacatg catatagaca cctacagata aactgatcag
    31981 catcgtgcgc atcataaact taacgtagtg tttttcagaa cacgaccgtt ccttatctaa
    32041 acgacaagcg tgtttattta gttgttttga acgtcttttt gaacacattt attcttagtc
    32101 ctccctactc ttgtctaaac atgaagtagt aattttcata agatgatttc attatataaa
    32161 taaaatcaaa agaagatgga ctattaggag agtatttttt ttgatttttt attgtttcaa
    32221 gaaaatcgga ataataactt atgtactttt taattttgtt aagtaatata tctagttata
    32281 tctagttata tctagttacc ttttctttga aaaaaacata aatcagctaa taaatatgtg
    32341 agacaaagct gccatccata aatactagct gattttttca gttaaatgtc tatttttttc
    32401 tctgatgatg gtatttccaa aatattccca gtcatctgga gtcggtggat ttttccaaat
    32461 tatctgttct ttattaaatt tttcaagtaa acaatcagat aaataaatat tcgtacgaga
    32521 agtgattcga ctctcaatca caatattgta atttttaaat cctttcactt gagaaataat
    32581 gtaatcggta taagcagatc cttgcgaaaa atcaatacag acatgaatcg gtgcttcaaa
    32641 atatgatacc ggacaaatac cgaccaataa aaagagataa tcataaaata agcgaatcat
    32701 gaaacgttca tcttttccca agaaatagcg tttattctct tgtatgacct tttggattgc
    32761 tgtactgaat attggatacg tctcgaagaa aaactgtagc tgctttttag acgtaaagct
    32821 agtcatctca aagtcgaata tccaattttt tcgattgaca tgcatcatac ccatacgaag
    32881 ttcttttcgt atatatagtc tttcttcttc agagatttca atcgaaaatg gtaattgatc
    32941 aatcaattcc actgacattt tttgactaat catgtggata tcatgaaaat gagcttccgc
    33001 aagtccaaat gcgccatcta attcaaattc ttcttccgtg atcaaaaaca acatgatata
    33061 agaaatctca tcaatgatct gctctttagg gatatgaaga aaagaaatat gtgataaatc
    33121 cttgatgatc ttcattcctt ctgagctctt aaagtattca tctgaaaaga aacgttttcc
    33181 gattggttga ttcccatagg ccctcaacaa actaatagtg gttagcaaat tgaatttgat
    33241 tcgttttgtt gcagacagtt ttaaattgaa cagatattca aaatattgca cgatactctt
    33301 tgcttcattc atgacgcttt ctctaaatgg catagaaaaa ccattaaaga ccccgaaata
    33361 taccccaaat aatacgttcc gtatgtttat ttcttcccca actaatatgt ttttctttaa
    33421 ctttatttga tgctgttcaa gaaaagagac taattctctt ctttttacat aggctcttga
    33481 tatgcttaaa aaatgattct ctgcaaattt ttcgatcgtt acttttgaat ccacgatctc
    33541 cgttaacagt cgagcaattt ttgatcgttg aaagtagatt cttcttaaat ttttgatatc
    33601 cgtcaaattc agacgttcga catggatctc tgcttcttct gaaatttgga tctctggctt
    33661 tgttttgaat tcagtaaatt ctttatttaa ttctatgata taatttcttg ttttaaattt
    33721 agacaaacct aatgtttcat ataacttagg cagcactaca taattctttt tctcaaattc
    33781 taaatatcta gctagcagca gtttttctct atcttcctct tctataaggt aatccaactt
    33841 catatcctac acctcaaaaa atgcctcata ccaattactt gatatgcaga tgaaagttca
    33901 tcttttcacc tatactgatt ttatgatgga ttatgcttgt tttttcatca gttattctca
    33961 ttttttatct tttttttgag aatattgcaa aaaatggaaa aatttatgag gaaatattct
    34021 atattttttg ttttattgtg ttaaaatgta caagatttgc gccatttgcg taaacaacca
    34081 caaaaaagag caggacggcc accgtcctgc tcttttactt attttaagtt ccattactta
    34141 ttaattggct aaacttctgc ttgtttctga tattgcttgt ttttctccaa tgatccgcac
    34201 ttctgtttct aaagacacat caaatttttc tttgattact tcttggatgt gcgcaatcaa
    34261 ttcaatataa tctgtcgctg tcgcatgatc gatattgacg atgaatccag catgtttttc
    34321 agagacttgt gcaccgcccc atttcaggcc ttgcaatcct gcttgttgga tcagctgacc
    34381 tgtatagtgt cctactgggc gcttaaagac acttccgcat gaagggtatt ctaatggctg
    34441 ttttgattga cgcaattcgg tcaactcatc cattcttgct ttgattgctt cataatcccc
    34501 tgtttgcaaa ctgaatcgag cttccaatac gatagcacgt aattcttgga ctttactgtg
    34561 acgataagaa aataccattt cgtcttttgt caaagttttc aatgttccat cttcaagcaa
    34621 aagatccact tcagcaaaaa catctttgat ctctccgcca tacgcacctg cattcatata
    34681 aaccgctcca ccgacacttc ccgggatgcc gcaagcaaat tcaaatccag tcaatgattc
    34741 tgccaaagct gcataagtcg tatcaatcag tgaggcacct gcttccgcaa tgaccatcgt
    34801 tcctttgaca tgaatctgtt tcatttcagt cagcatgatg actacaccgc gaatcccgcc
    34861 atcttgaacg atcagattgc ttgcatttcc taataccatc caaggtatat catggattcg
    34921 gcaataatcg atgatttgct ttacttcttc ttgttttttc gggaatgcaa ggacatcagc
    34981 tggtccacct gttttcgtaa acgtatagtt catcaatggt tcatcaaaca atatagtaat
    35041 cgtggctaag ctttcaacta tttcttcttt attcactgag gattttcctt tcttttctca
    35101 aacgtcctca ttattctatc acgcttaata caatcttgcc agtcttgttc aaagttgatg
    35161 acggtagtga tctttaagca cttcctcaca taattcatga cttcttacaa cttctttttg
    35221 tttaagcaat tctgtttccg atttacctaa acggatctga gaaaagaagg cctctaccat
    35281 tggctcaaac ccgcgtttga ctagcgtgtt tgtccagtcg ccaaattctt tcactttttt
    35341 tccatcagca tcttgaatga caagctgggt cagatcgttt acttcataag taccattttt
    35401 acttgttact tgatattttt ctatattagc gccacttgct aaatccatcg ttaaaatagc
    35461 cgtttgattt tgtgtttcta attgtaaaat ggcatattcc aaaaattcct ttgtttctct
    35521 tatctggtat tttgttctca aaatgggttc atctaataaa tacacagctg tatcaataag
    35581 atgtaaaaac aaatcataaa ggacgaactc tgtcgtttct tttgccgcta ttcgattttt
    35641 ttgcaggtgg atcaaccgct tatctgggat acgtttcaat tcttctacca taggagcaaa
    35701 gcgccggttg aaaccgatca tcaaaattat ttggttctta tcagctaatt cttgcaattc
    35761 acgaacttca tttagatgga cactcagtgg tttgtcaata taaacatgga taccattttc
    35821 tagacatttt ttggctaatt cataatgtac ttttgttgct gcgtggatca tacatgcttc
    35881 gattttttct tctaaaagct catcgatcgt ttcatataga tgttggaacc cgtactcttt
    35941 ttgaattctt tcttttgttt ctttatttct tgttgcaaaa taaaaatcaa gtgttccttg
    36001 ttttttcgca taagttggta aatatgcttt ttctgcgata ttccctacac cgattacacc
    36061 aatcttcatc tactttcctc ctggatcatt tagttacttt catcttacac cattttttac
    36121 taaaatgagg tacaatagta tcgcaaaggt aaggaaatta attcgaagga gtgtgctttt
    36181 attgaaattt atctcttgga acgtaaacgg gcttcgtgcc atcgtaaata aaaatttttt
    36241 agaagttttt catgagttag acgccgattt tttctgtctg caggaaacga aactccaagc
    36301 aggacaaatt gatttagatc ttccaggtta ttatcaatat tggaattacg cggaacgaaa
    36361 aggctattcc ggcacagcga tttttgctaa aaaaccagca ttgaatgcca cttacggaat
    36421 gggtatcgat atccatgata cagaaggccg tctgattact ttggaatatt ccgatttctt
    36481 tcttgtaacc tgttacacgc caaattctca aagcgaatta aaacgtttag attaccgatt
    36541 agaatgggaa gaagcctttt ataattattt ggaaaatcta aaaaaacaaa aaccagtcat
    36601 cgtgtgtggg gatctaaatg tcgctcatca aaagattgat ttgaaaaact ggaaaacgaa
    36661 tcaaaaaaat gctggattca ctccagaaga aagagcggct ctttctcgac tgttggataa
    36721 cgggtttatc gatacattcc gttattttta tccaacccag gaaggtgtct actcttggtg
    36781 gaactaccga ttcaattcaa ggaaaaacaa tgctggttgg cggatcgatt actttttgac
    36841 gagcaaagat ttagagccag gactagctga tgcaaagatc catacggaca ttatgggcag
    36901 tgatcattgt ccagtagaat tagatttgaa ataaagaggt tgtgaaaaag tcgtttagtt
    36961 tcgagtatta agaaaaattt tgtgaaaatg gctttccaca ttttgcataa atttggcata
    37021 ataccgagaa actggctttt gaacactgtt tatcgagaga ttgtgaaaaa gctgtcctgc
    37081 atcaagtaat aagaacagcc aaacaaaaat agttcctcat atttttcgtt tggttgggct
    37141 tattaccgca gatacaagct tttgaacacc gtttattaag aggttgtgaa aaagctgcac
    37201 tgcatcaagt aataagaaca gccaaacaaa aatagttcct catatttttc gtttggttgg
    37261 gcttattacc gcagatgcaa gcttttgaac accgtttatt aagaggttgt gaaaaagctg
    37321 cactgcatca agtaataaga acagccaaac aaaaatagtt cctcatattt ttcgtttggt
    37381 tggacttatt accgcagatg caagcttttg aacaccgttt attgagaagt tgtgaaatca
    37441 gcgtcctgac ctgagtatta gagaaacaaa tggcaaaata gttcctcata ttttgctatt
    37501 ttttgagcta ataccgaggg tcagctgatt gaacaccgtt tagtggagaa gttgtgaaaa
    37561 agtcgcctac tttcgagtcg taagaaattt ttttgaaaat ggttcctcac aactttgcat
    37621 aaatttgact taataccgag aagtcatgat ccccatctaa ctccaaatca caaggaatga
    37681 gttcaaaaac tagcttttct caacaaatat tacataaaaa attctatgtt ttttgttaaa
    37741 tttatttgct tttttcaaaa gtatgttaca gtaatttccc aaggaggttt tacagaaatg
    37801 aattttgttg ccatggattt tgaaactgcc aatcatcagc cttatagtgc ttgttctctt
    37861 gcgctagtca tggtaaaaaa tagccagatc gttgatgaat tctatacatt gatacagcct
    37921 gagactcctt ttttctggcg aaatgtccaa attcacggaa tccatcaaga agacgtacgc
    37981 aatgcgccga aattcccaga agtctggcaa actatccaac catattttca aaaaaatcgt
    38041 ttagtcgttg cacataatgc tgcttttgat acaaaggtct tagcgggatg cttagattat
    38101 tatcatcttg aacagcctaa ttatctttct ttatgtacag tgaaaagtag ccgtcgcctg
    38161 tttcctgaat ttccaaatca tcgattgaac actgtgtgcg aaaatttgaa catccaatta
    38221 gatcatcacc atgatgcatt ggaagatagt cgtgcatgtg cggaaatcct gctttatcaa
    38281 gaaaaaaaat tcgggacaga tccattgaaa aaacttgtga ctataaagta aaagaatact
    38341 tatgaaacac acaaagaggt cgtgagcctg ccgtttcact ccgagtcaca aggagcaatt
    38401 tcaaaaaata gcttctcatg tttattaaat attgtgactg gtgaccgagg agctggcagg
    38461 agaacaccgt ttattggaga ggttgtgaaa aagctgttct gcatcaagta ataagaacag
    38521 ccaaacaaaa atagcttctc atatttttca tttggttgga cttattaccg cagatgcaag
    38581 cttttggaca ccgtttacc
//
LOCUS       DAFENC010000024        37386 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.024, whole genome shotgun sequence.
ACCESSION   DAFENC010000024
VERSION     DAFENC010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37386
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.024"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..614
                     /locus_tag="LP493_001582"
     CDS             <1..614
                     /locus_tag="LP493_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBL2133738.1"
                     /translation="VFAPLEGEDLASFLVGAAIMMIGMTLFLFGADYSMMEVGDLVGK
                     YMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQQVYDISDGEIGRVLLIGIVSVGTG
                     VFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFTSSEFMPIAFDSGGVTTGPVTVPFI
                     LALAGGMTSMIKQKKNENDSFGMVGIASLGPILAVMILGVIFQ"
     gene            611..1384
                     /locus_tag="LP493_001583"
     CDS             611..1384
                     /locus_tag="LP493_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBL2133739.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            1381..1779
                     /locus_tag="LP493_001584"
     CDS             1381..1779
                     /locus_tag="LP493_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HBL2133740.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            1964..2635
                     /locus_tag="LP493_001585"
     CDS             1964..2635
                     /locus_tag="LP493_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133741.1"
                     /translation="MNFLVVLKDTLIERFTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            2694..3134
                     /locus_tag="LP493_001586"
     CDS             2694..3134
                     /locus_tag="LP493_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133742.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            3146..3814
                     /locus_tag="LP493_001587"
     CDS             3146..3814
                     /locus_tag="LP493_001587"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBL2133743.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            3878..4501
                     /locus_tag="LP493_001588"
     CDS             3878..4501
                     /locus_tag="LP493_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HBL2133744.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            4557..4943
                     /locus_tag="LP493_001589"
     CDS             4557..4943
                     /locus_tag="LP493_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HBL2133745.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            5156..6547
                     /locus_tag="LP493_001590"
     CDS             5156..6547
                     /locus_tag="LP493_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HBL2133746.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            7158..7526
                     /locus_tag="LP493_001591"
     CDS             7158..7526
                     /locus_tag="LP493_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HBL2133747.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            7706..8647
                     /locus_tag="LP493_001592"
     CDS             7706..8647
                     /locus_tag="LP493_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HBL2133748.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            8716..9447
                     /locus_tag="LP493_001593"
     CDS             8716..9447
                     /locus_tag="LP493_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HBL2133749.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            9591..11771
                     /locus_tag="LP493_001594"
     CDS             9591..11771
                     /locus_tag="LP493_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HBL2133750.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            11791..12273
                     /locus_tag="LP493_001595"
     CDS             11791..12273
                     /locus_tag="LP493_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HBL2133751.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            12289..13050
                     /locus_tag="LP493_001596"
     CDS             12289..13050
                     /locus_tag="LP493_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBL2133752.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            13181..14515
                     /locus_tag="LP493_001597"
     CDS             13181..14515
                     /locus_tag="LP493_001597"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HBL2133753.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            14822..15307
                     /locus_tag="LP493_001598"
     CDS             14822..15307
                     /locus_tag="LP493_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HBL2133754.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            15300..15983
                     /locus_tag="LP493_001599"
     CDS             15300..15983
                     /locus_tag="LP493_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HBL2133755.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            16109..18754
                     /gene="polA"
                     /locus_tag="LP493_001600"
     CDS             16109..18754
                     /gene="polA"
                     /locus_tag="LP493_001600"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBL2133756.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            18799..19635
                     /gene="mutM"
                     /locus_tag="LP493_001601"
     CDS             18799..19635
                     /gene="mutM"
                     /locus_tag="LP493_001601"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HBL2133757.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            19599..20228
                     /locus_tag="LP493_001602"
     CDS             19599..20228
                     /locus_tag="LP493_001602"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBL2133758.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            20280..20612
                     /locus_tag="LP493_001603"
     CDS             20280..20612
                     /locus_tag="LP493_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBL2133759.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            20924..21415
                     /gene="nrdR"
                     /locus_tag="LP493_001604"
     CDS             20924..21415
                     /gene="nrdR"
                     /locus_tag="LP493_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HBL2133760.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            21438..22811
                     /locus_tag="LP493_001605"
     CDS             21438..22811
                     /locus_tag="LP493_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBL2133761.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            22811..23737
                     /gene="dnaI"
                     /locus_tag="LP493_001606"
     CDS             22811..23737
                     /gene="dnaI"
                     /locus_tag="LP493_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HBL2133762.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            23866..24306
                     /locus_tag="LP493_001607"
     CDS             23866..24306
                     /locus_tag="LP493_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBL2133763.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            24450..25151
                     /locus_tag="LP493_001608"
     CDS             24450..25151
                     /locus_tag="LP493_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HBL2133764.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            25148..26269
                     /locus_tag="LP493_001609"
     CDS             25148..26269
                     /locus_tag="LP493_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBL2133765.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            26284..27516
                     /gene="pepT"
                     /locus_tag="LP493_001610"
     CDS             26284..27516
                     /gene="pepT"
                     /locus_tag="LP493_001610"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBL2133766.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            27648..28556
                     /locus_tag="LP493_001611"
     CDS             27648..28556
                     /locus_tag="LP493_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HBL2133767.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            28591..28863
                     /locus_tag="LP493_001612"
     CDS             28591..28863
                     /locus_tag="LP493_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HBL2133768.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            28874..29920
                     /locus_tag="LP493_001613"
     CDS             28874..29920
                     /locus_tag="LP493_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBL2133769.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            30171..32780
                     /gene="clpB"
                     /locus_tag="LP493_001614"
     CDS             30171..32780
                     /gene="clpB"
                     /locus_tag="LP493_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBL2133770.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(32931..33617)
                     /locus_tag="LP493_001615"
     CDS             complement(32931..33617)
                     /locus_tag="LP493_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133771.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(33595..34089)
                     /locus_tag="LP493_001616"
     CDS             complement(33595..34089)
                     /locus_tag="LP493_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBL2133772.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(34109..35329)
                     /locus_tag="LP493_001617"
     CDS             complement(34109..35329)
                     /locus_tag="LP493_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2133773.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            35476..37311
                     /gene="lepA"
                     /locus_tag="LP493_001618"
     CDS             35476..37311
                     /gene="lepA"
                     /locus_tag="LP493_001618"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBL2133774.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEDEPKK"
BASE COUNT        12417 a         6550 c         8101 g        10318 t
ORIGIN      
        1 ttgtttttgc accgttagaa ggagaagacc tcgcttcatt tctggttggt gcggcaatca
       61 tgatgatcgg aatgacgctc tttttgtttg gagcagatta ttctatgatg gaagtcggag
      121 atctagtagg gaaatatatg atcaaaaaga aaagtttgac cgttttggtc agtttgggat
      181 ttgctatcgg gatcgtgatc acgattgctg aaccttccgt gcaagttttg ggacaacaag
      241 tatatgatat atctgacgga gagattggca gagtgttgct gattgggatc gtcagcgtcg
      301 gcactggagt atttctagcc tttgcgctgc ttcgggtcgt attcaagcta tcctattatc
      361 aattgatggc tataggctac ataggcgttt tgatcgcctc atttttcacc agttccgaat
      421 ttatgccgat tgcttttgat tcggggggag tgactactgg tccagtaact gttccattta
      481 tcttggccct tgccggaggg atgactagta tgatcaaaca aaagaaaaat gaaaatgaca
      541 gttttggaat ggtcggtatt gcttcgttag ggccgattct tgccgtgatg attttggggg
      601 tgatcttcca atgagtttct ggcagcaagt gatagatgga atcgaaatcg ttaccatgga
      661 agtcattttg gcagtggcac ctatcgtaat cctatttgtt ttaatgaata tcattagttt
      721 tcgtatgcgc aaaaagcgtt tctttgacat tatgaaaggt ttcttgataa cgactattgg
      781 gttgatcctt ttcctgcacg gagtcaatat ggcttatgta ccggtaggac agcatttagg
      841 cagtgctatt gcgggattgc cttacaatta tatactggtt ccccttggct ttttaatggg
      901 gttcttagta gggtttgctg agccggcgat tcatgtaatg atcaaacagg ttgaagaatt
      961 gagcgagggg agaatccgat cgaaaatcat gctgatggta atttcaattg ggatcggcgc
     1021 agcagtagga ttgtctatgt ggcgtttgct cgtcggattc tctctttatt atttcttgat
     1081 cccaggatac gggctagcat ttattttagg acgaaaagtg gacaagatct ttttagcaat
     1141 ggcttttgat aacggtggag tagcaacggg cccgatgtgt tcgacattta ttttatcaat
     1201 gagcgtggca atcgctgcac aaattgaagg aagagatccg atcattgacg ggtttggtgt
     1261 ggttgcaatg attgcattga caccaatatt atccacttta gtactaggat atatttataa
     1321 acgaaaagat gaaaaagaca gaatcgaaaa agaaagattg caaaaattgg gggaaagcaa
     1381 atgaaagatc ttgtagcatt gaatcttcac atgattgtga cgatcgttga cggaggaatg
     1441 ggcgaagatg ttatcgactt ttcaaaagaa gcaggtgcag caggcggaac gatcttacat
     1501 ggaagaggtt ctggtgtaca tgattcaggg aaatttttag gtttggacat ttcgccagaa
     1561 aaagatattg tgttgacatt agtacccgat agtttgacga ataaagtaat ggatgcgatt
     1621 ggtcaaggca tcaacatcga tattccaggt aatggtattt gttttagtat tgatgtagac
     1681 aaagtcattg gtatcactaa gattcatcaa tatcgagaaa ttatcggaat gcaagaactt
     1741 ttagatgaaa ataacgatag agaaaagtct gaatcataga caagcgtttg aagaggaaat
     1801 aaacacaaac aagaaggcgg atgagcgtta tttccgcttt tttgtttgta tttttctcgt
     1861 gaatacttat gaaatagtaa atttttatga aattctactc taagcatcag actttctttt
     1921 caaaatatgc tattttaaaa atgatgaaaa aagggggaga aaaatgaatt ttttagttgt
     1981 tttaaaagat actctgattg agcgatttac atttctatat gttcaattgc aggaaaataa
     2041 aacattgctg catttttcac cagagttcca tctagagggg ctaacattag gagaaatcta
     2101 tcaagcagaa gggctgtcgg ctgttttgca cttttttaag gtagaattgg aattaccagt
     2161 aaaagattat atcgagcttt ctcttgaatc ttgggatcga gcagtggttg aactgtttcc
     2221 agaaggttta atgatcgata caaacgatgg gaagatccat ctgactgcag cagaactgca
     2281 aaaacaaatg cgttatcaaa tagatgacga aaattctttt tctattttta gacgtcagca
     2341 aaagattcta aaaagctttt taaaagtgat cagtaaaaaa cggaatctga tcaaaacgac
     2401 acagctgttg aaaaaatatc caggtctgct tcacacgtct attcaatttc ctcaattgat
     2461 tacgatgatc catcgtttta tacgtatgca acagctacca tctaagaagc tgtttcttcc
     2521 attgacggac acatttcgag tagtcaacag agaagataaa aagaaagtga ttgtgattga
     2581 ctttaccaga aatcggaatg tccttcacca agttgcaatg gaaaaggcca attaaggctt
     2641 tttctttttg gatttttttg tcataataaa tattagatga tggaggagat aatatgatgc
     2701 aaacatggtt agaaaggcta atacgatttc agcagaacta tcacaaactt atgcagggaa
     2761 gatatgcgaa atttgatcag ttgaatcgcg gtctattgat cgctgcgctt gtctttagtt
     2821 tgctaagtcg ttggttgccc tatagaatcg gacaattgtt gttcatcgtc tttttcggat
     2881 ggatgatatt tcgtttccta tcaaaaaaaa tctaccccag actaaatgag aatcaacgtt
     2941 atttgaaata tcttgataga gtcaaagaaa aatatcatca gataaaaaac aaaaagcaag
     3001 tcaaaatgga tcgaaaaagt tatacttttt ttgagtgccc gaattgtcat caaaagcagc
     3061 gtgcacctaa aggaaaagga cgaatacgtg tgacatgcaa aacatgtggt ataaaattcg
     3121 aaacgaatgt ttaagggaga aaagaatgaa attagtatta ttacgtcatg gcgaaagcga
     3181 agcaaatttt gaaaattact ggacaggatg gctagatgtc gccttaacag aaaaaggaaa
     3241 agaacaagca gcagttgccg gtcaaaaaat gcttgaagcc ggacttcaat tcgatgccgt
     3301 ttatacctct gttttgaaac gtgcgattct taccggacaa gtcgcactag aagaaatggg
     3361 tcagttatgg cttcctataa taaaaacatg gcgtctaaat gaacggcatt atggggatct
     3421 tgtgggtaaa aacaaagata agatgaaaga aatatacgga aaagatcaag taaaaacatg
     3481 gcgcagagga tatacggaag ttccgccgtt aaccgcagaa aatagatttg accgcagata
     3541 tgatcacttg gatccgcatt tgatcccata cggagaaagt ctggaaatga cagtgaatcg
     3601 gatcattccc ttatggcaag atcatctagc accaaaacta aaagatcggc aagatttact
     3661 agttgtgggt catggtaata gcatccgagc actgacaaaa tatttagaag atgttcctga
     3721 agatcaaatg gatacgatcg atatcccaaa tgcacaacca atccagtata cattagcaga
     3781 tgatttgaca attctggaca aaaaaatact ttaaagaaca cctttatcta aaagtgagag
     3841 atagaaaaaa gaagcaaagg aatggaacaa aaggaacatg aaaaattata tatgggactt
     3901 tgatggtaca ttgtttgata cgtatcccgc aatggtagat ggtgcatggc aagcactaaa
     3961 agattttggt atcagtatgg acaaaaaaga aatctacttc aaaatgaaaa agtattctac
     4021 tagttatttg atcaatgaat caaacttgaa tgccagagag tttaatgaat tatttcaccg
     4081 atatgaaaaa gaaagtacgg aagtttcccg tccatttcca gaaacgaaac aagtactgga
     4141 aatgctaaaa gacaacggcg gtcgtcattt catcctgacc caccgtttga cagaatcaac
     4201 atggggcctg ttaaaagaac atcgattggc acatctgatt gaggaagtag tagggatcga
     4261 tcaggacttt cctcgtaaac ctgatccagc atctttaaat tatttgatcg atacttttca
     4321 tttagaaaga acagacacga tgatgatcgg cgatcgtcgt ttagatatcg aagcagggaa
     4381 aaatgcagga gtcgctactt gtctttacga catcgatcat tttctgggtg agatcccggc
     4441 agattatgtg gtaggaaatc tgaatgaaat ccttaccttg cagagcatca ttaaaaagta
     4501 gtatcccctt tcaaaggaga tatgttataa ttttcataaa ggagtgataa aattatatgg
     4561 aaatcagaag acaaaaagaa gttgtagaag catttcatta tgatatgaga ttgccgaacc
     4621 aagaagtaga aacagatttg aaagtaggct tctcgccttt aaaagaaacg atcgaaaact
     4681 atccgaaaga acatagcatc gtaggagcac gcttagagtt ccgtttagtg tttgatacat
     4741 atgttttatc tggaagtgtg agtcagatca atcatatcct caatcggaaa attgaaggtc
     4801 aaaatgatgt cacacaagaa gaagtggacg agctagtagc accgttattc gatatcgtac
     4861 gccgaatgtc ttatgaggtg acagagatcg ccttagatca gcctggggta aaattgaatt
     4921 ttcaatcaga aaaacaagaa tagacagtaa aaacatacct gcgatagatt aaagctatca
     4981 caggtatgtt tttttattac taattgtaag caaaaagaat gtcatttcga taaaaatcgt
     5041 ctaaaatata aaagtcactg aaaaaaattt tttcaggagg atggttgaag aatcattctc
     5101 gggaaccttt acttccttcg atggacttgt cattaataat atgaggagga gaaaaatgac
     5161 aacactcatc acagttttag tggttctagt ttttgcggca ttattatatg tgttctatcg
     5221 tatgcaaaag cgccatacaa aattttcaac acgcgtcttt acagcattag gagttggtat
     5281 cgtctttggc ggtctgcttc aattgatctt tggtgtagac gacaaagtcg ttactcaatc
     5341 aatggaatgg atcgggattg taggtcaagg atatgtatca ttcttgcaaa tgctagttat
     5401 gcctttagtg tttatttcga tcattggtgc attcacaaaa atgaaagttt ctgaaaagct
     5461 agggaaaatt agtgcgactg tattgacttc tttacttgga acaacagcta ttgcagcatt
     5521 gatcggaatt ggttcaacaa tgctgttcgg actccaagga gctaaattca cacaaggagc
     5581 tgcagaaaca gcacgaatct ctgaactggc aacacgtcag gaaacagttg aaaacttatc
     5641 gattccacag cagattttat cctttatccc taaaaacgtt tttgctgatt tagcaggtag
     5701 tcgtgcaaca agtacgattg gagtcgttat tttcgcggca tttgtcggaa tcgcttatct
     5761 aggcgtgaaa agaaaagcgc caaaagaagc agcattcttt tcagatttag tcgacagtct
     5821 gtataaaatc attatgcgga tcgtgacgct tgttttgcgt ttgacacctt atggagtatt
     5881 tgctttgatg acaaacgttt tggcaacaag tgattttgca gctatcgtca atttaggtaa
     5941 atttgtcgtt gcttcttacg tagcattgct tgctgttttg attgtccact cactgatttt
     6001 gattggtgca aaagtcaatc caatcaacta tttcaaaaaa gcctttccgg tattgagctt
     6061 tgcgtttact tcacgttcaa gtgctggagc tttgccattg aatatcgaga ctcagacaaa
     6121 agctttagga gtagatgatg caacagctaa tttctcagca agttttggtt tgtctattgg
     6181 acaaaacggc tgtgctggcg tttatccagc tatgttggca acgatcgtcg caccagcagc
     6241 tggagtgaat gtctttagtt tggaatttat tttgatgctt gtggcaattg taacaatcag
     6301 ttcttttggt gtagctggag tcggtggggg cgcaacattt gcttcactga tcgttttagg
     6361 ggcaatgaac ttgccagtag caatcgttgg gttagttatc tctgttgaac cattaatcga
     6421 tatggcacgt acagcagtaa acgtcagcgg tagcatggta gctggtatcg tgacaagtgc
     6481 acgcatcaaa gatttagatc gcgatgtcat caatgatgat tctaaagtga tcgatgtgaa
     6541 tgcatagtca aaaagaggtt gtgatagaag tggtcagctt taagaaataa gaagaagttt
     6601 cctaaaaata gtttctcaaa tttttgtgaa atttcggctt atttccgaga agctacttct
     6661 gaaacaccgt gaataagagg ttgtgaaaaa gctgccctgc atcaagtaat aagaacagcc
     6721 aaacaaaaat agttcctcat attttacgtt tggttgagct tattaccgca gatgcaagct
     6781 tttgaacacc gtttaagaaa gaggtcgtga gcctgccgtt tcactctgag tcacaaagag
     6841 caatttcaaa aaatagcttc tcatgtttgt tgaatattgt gtcttgtgac cgaggagttg
     6901 tcaggagaac accgtttacc agaggttgtg acttgttttt agtcacgacc tcttttttta
     6961 tttattccat ataaatacac attatttatt ccgaaaagtg aaagcgcaaa taacaaaaac
     7021 aaccaactta tttattatta aagaaaagcg tatttaagta ggacgattct gttgagagct
     7081 ttcgtagatt ttcccatttt cctatggtaa actgacaaag ttgagaatgt tagaacagat
     7141 cgtttaggag gaaacagatg tttacgaatg aaataaaaat catgctttat gtggacgatg
     7201 tagaaaaaaa tgcaacgttt tggagagcag ttggctttgc ggaaaaagat cgtcaagaaa
     7261 tggatgggac gcttataatt gaagtaggag ttgaggacag tcaaacctca tttctgttat
     7321 atgatcgagc atttgttgag tcccattcac ctggcacagc tactagtgcc ccatctttga
     7381 tgttttacag taaagatatc tttggactat ataaaaaaat gcagacgcaa tcagtcacat
     7441 taggtgatat ggtacagctt ggagaagaat atgtctttaa ctttgctgat cccgatggca
     7501 actactttgc ggttacaggt aaataataga aataaagact ttgtttttct gtgcgaaaca
     7561 ggaaagcgaa gtctttttaa ttcaaataat aatattatgt aaacaaaaaa ctttccatgc
     7621 gtaattatac acaagcaaat aaatcgtcaa atgcgaacgc cttctttata ctgtttagga
     7681 acgaaaagaa ggaaggaaga aatacatgga ttatcaagta ctgctttatt acaattatac
     7741 aaaaatcgaa gaaccagagg aatttgccaa aaatcattta gccttttgca aatctttgga
     7801 tcttaaaggt cgtattctag tagctgaaga aggaataaat ggtactgtgt ctggaaccgt
     7861 tgaaaacacg actgcctata tgaaagcaat gaaagctgat cctcgatttg ctgatacgat
     7921 gttcaagatc gatccaagcg aaggacatgc ctttaagaag atgtttgtaa gataccgtcc
     7981 agagcttgta agtttaaagc tagaagagga cattgatcca aaccaagtga caggtgccta
     8041 tctttcaccg caagaattta aagaagctat tttagatgaa cagacagtgg tgattgatgc
     8101 acggaatgat tatgaatatg acttgggaca ttttcgaggg gctgtacgcc cagatatacg
     8161 cagttttcga gagcttccag actggatccg cgagcacaaa gaagaattta tggaaaaacg
     8221 ggtagtgacc tactgtactg gtggcattcg ttgcgagaag ttttctggtt ggcttgtccg
     8281 tgaaggattc aaagatgtcg gacagctgca tggcggtatt gctacttatg gtaaggatcc
     8341 tgaagtccaa ggagaattat gggacggcaa gatgtatgtg tttgatgaac ggatcgctgt
     8401 cgatatcaac caagtagata aacaaatcgt cggtcgcgac tggtttgacg gaacaccatg
     8461 tgaacgatat atcaattgta gcaatcctga gtgcaatcgt cagattcttg cttccattga
     8521 aaatgaagaa aaacatttag gagcatgtag catagagtgt gcgaaacatc cgcgcaatcg
     8581 ctatgttcaa gaccatggaa tctctccaga agaagcagaa ctgcggttta cagctttaat
     8641 taaatagaaa acaatagttt tgattgtcga ccatttccaa tatgcgctat actagcgttg
     8701 aggatggtga tccacatgaa atcattgatt tatgctattg gggatgtcca tggcaaacat
     8761 gagctttttg aaaaacttat tcactattat gatccaaaga tccatcagct tgttttatta
     8821 ggggatctca atgatcgagg tcctcgtaca aaagaatgtt ttttattagg aaagcaatta
     8881 gtcgaagaaa caggagccat ttacctccgg ggaaaccatg aagaatattt tttgcaattt
     8941 ctgcaatcac cggaggactg gtatgcgcct tatatgagaa atggtggaaa agaaacgttt
     9001 gaaagcctga ttcacccagg ggcatcggag gaatactccc caactgaaat ctcgatgatg
     9061 atccaatcga gatattcaga actgattaaa tttttagtcc agcgcccctt gtattatgaa
     9121 tgggaaaatt atctttttgt ccatgccggt gtggatttga caaagaaaga ctggcgtaag
     9181 acaagtctaa gagactttat ttggataagg gaaccatttc atgaagggaa aaacaataca
     9241 ggtaagacaa ttgtatttgg acatacgatt acaccaatgc tccatggaga tatgcagaca
     9301 acagacctct ggattcagga tcataaaatc ggaatggacg gtggggctgt attcggaggg
     9361 tcattgcatg gggttgtttt tgacaaggaa ggtattcttc aagatattga atatcagaac
     9421 aacgaaggac cttggcatgg aatctgacta atggaaagaa tgaaggagct gtgactttgt
     9481 tgcggctctt tttattttta tagagaatat tgtttctttc agtagtttaa cccaggataa
     9541 aaagtatgat agaataaaga agcaattttt agcagaaaag aggcatttta atgacggaaa
     9601 atttgaacca gacgatcatt cagcttgtac aaaaagaact ttcagactat cgtcctaagc
     9661 agttgactac tgtacttaat ttgttaaatg aaggaaacac tgttcctttt atcgcgcgtt
     9721 accgaaaaga aatgactgga agtcttgatg aagtccagat tcgtgaaatc gaagagcggt
     9781 atgcctatct tgaaaactta gaaaaacgta aaactgaagt gattcggcta atcgatgaac
     9841 aagggaaact gactcccgag ttagaagcag aaatcaccca agccgtgaaa atgcaacaag
     9901 tggaagattt gtatcgtcca tacaaacaaa aacgacggac aaaagcaacg attgctaaag
     9961 aaaaaggact tgaaccactc gcgaagtggc tgatgcagct tacagatgga gaggtgcaat
    10021 ctgaagcaga aaaatatatt gacaaagaaa aagaagtctc ttctgccgaa gaagcgttgc
    10081 acggtgctca tgagattatt gctgaacaag tcagcgataa tgcaaaattt cggacttgga
    10141 ttcggtctta tacgtataac aaaggtatgt atgtcagcaa tgtcaaggat gagcaagcag
    10201 atgaaaaagg cgtatatgaa atgtattatg actttgcaga acccgtccat aaaatggttt
    10261 ctcatcgaat attagctact aatcgtggag aaaaagaaga tattctgaaa gtattctttc
    10321 aagtagatga agcagcaatt ttagcttact tggatcgcca aatagtcaaa aatcctgcct
    10381 ctccttcttc ttcattcgtc agagaagcct atcaggatag ttataaacgc tttattcagc
    10441 cagcaatcga gcgagaactg cgcaatgaat tgactgaaaa ggcagatgag caagcaatcg
    10501 ctattttcgg cgaaaacctc cgtaatcttt tgttgcaacc gccactaaaa ggtaaagttg
    10561 tcctgggatt tgatccggct tatcgtactg gatgtaaact agcagtcgta gatgcgacag
    10621 ggaaagtttt agcaatcgaa gttatttatc ctcataaacc tgcagcgcaa gcaaaaagag
    10681 aagctgctgg accagctttt atccaattaa ttaataaata tcaagtagat atggtagcta
    10741 tcggaaatgg tacagccagt cgggaatctg aactttttgt ggctgagcag ttgaaatccg
    10801 ccgaccataa aacctattac gctatcgtca acgaagcagg cgcttctgtt tactccgcta
    10861 gcgaaattgc acgaaaagaa tttccgcatc tacaagttga agaaagaagt gctgtttcta
    10921 ttgcccgtcg cctgcaagat cctttagctg aattagtcaa aatcgatcct aaagctgtcg
    10981 gagtaggcca gtaccaacat gacgtttctc aaaaacgttt ggctgaacaa ttggattttg
    11041 ttgtggaaac agcggttaac caagtaggtg tggatgtgaa tacagcaagc ccgcagctct
    11101 tgcagcatat atcaggattg aataaaacaa ctgcccaaaa cattgtcatt tatcgtgaag
    11161 aaaacggaga attcaccgca cgaactcaat tgaaaaaagt gccacgctta ggaccaaaag
    11221 catatgaaca agcaatcgga ttcttgcgag tccctggtgg gaaaaacatt ttggacaaca
    11281 caggtatcca tcccgaaagt tattctattg caaaagaaat attaacttca gtccaacttt
    11341 cagaaaaaga gcttggtaca gaagaagcag tagaaaaatt gacacgatta tccgtagaga
    11401 aactggctga aagcctatca gtcggagaag aaacgttagc cgatatttta gctgggctga
    11461 cacaacctgg acgagatatg cgtgatgaga tgccagcgcc cttattacgt acagatgtat
    11521 tgagtatgga agacttgaaa ccagggatgg aattgactgg aacggtccgt aatgtcattg
    11581 acttcggcgc atttgttgat atcggtgtga agcaagacgg acttgtccat atatcgaaac
    11641 tcagcaaaaa attcgtcaag catcctacag atgtcgtgtc agtaggagat atcgtaacag
    11701 tttggataga acaagtcgat acgaaaaaag gcagaatcag tttgacgatg ctttcccctt
    11761 atgaagagta acaatgagga gtaacaaaaa ttgacacaag aagaactgca gcagttagta
    11821 gaagagatat cattaaaaag cttccagctt cctttcaagc accaagcaat gttcaatcca
    11881 cgcttacgta caactggcgg gcgctatcat ttaaacgatc atcatttaga ttttaatgcg
    11941 aagctatttg aagagtcaga cgaagagacg attgcaggaa tcatcaaaca tgaactttgc
    12001 cattatcatc ttcatctagc tggaagaggg tatcagcata aagatatgga tttcaagtat
    12061 cttttgaaaa aaacaggagg gttgcgctat gcaccagcct tgacgaagaa acagataaag
    12121 atggagtatt atcgatgcca agattgttct gccacgatct gccgcaagag aagaatcgat
    12181 gtacgcaaat atcgttgtgg aagatgtcat ggagaaatca aatggattga gacaaaaaga
    12241 gaagacttta atgaagcaca aaaaatcaga tgaaaggata gaaggccttt ggaaaaaagt
    12301 gagcagagga atctaaaaga ctggaatcag ctattaaatt ttttagccgc acctgaagag
    12361 ggaaattttg aggaactgac ggcacctaca cttattttag ctggaaactg tcttcctatc
    12421 ttagctgata aagcagcaca aatgtattta aatggccaag tagatcaatt gtttttggtc
    12481 ggaggggtgg ggcatgcgac tagaatcctt tatgagaatt ttgaaaagca aggatttcat
    12541 tttgaagatg gcatgagtga aagtgaaatc tgtcgtcagt atctaaaaga agtctatgat
    12601 ttgcccgata aggcttttct gatagaatcg aagtctacaa attctggaga gaacgccact
    12661 ttttcactgg agattcttca ttccttagga gctgtaccag aaaaaatctt attgatgaat
    12721 gatccgacac tgcaacgcag gactcgagca acttttgaga aagtatggca aaatgaacaa
    12781 actattttcg cgaatgctgt gccatttgtg ccggaaatcc ttcacttttc tgaagagatc
    12841 atctttacag caaaagaact gaatcatcaa tggcctaagg aatatttcca tgcgctagta
    12901 ttaggagaaa tggaacgtct ccatgacgat gagaacggct atggtccgaa aggaaaagat
    12961 tttattcctc acattgatat atcagaggaa gtttggtctt cttacaccag aattaaagag
    13021 tcaataaaaa cggatttttc tcgtacttga ccattttagc aagcgaatcc tcctttccaa
    13081 ataaatttgg ttgaaatttt caatcgttta taagataatg aggagcgtgt tgaatgtaat
    13141 agctaaaaga atggacgcta gataagagaa gaggattcaa atggaaaatc aaaataaatt
    13201 gtatcatttt gttggtatca aaggttcagg aatgagctcc ttggctcttg ttttacatga
    13261 acaaggtcta aatgtccaag gatcagacat tgaaaaatat ttctttacac aaagagattt
    13321 agaaaaagca aatatcacga ttctgccatt taacgcagat aatgtaaaac cagggatgac
    13381 gatcattgca ggaaatgcat ttcctgattc acatgaagaa atccagcgag caaaagaatt
    13441 aggtttggaa gtgattcgct atcacgactt tattggtcat tttatccaaa attatacgag
    13501 tatcgctgta acaggctctc acggaaaaac aagtacgact ggactgctct ctcatgtatt
    13561 gagtggtgtc cgtccaacaa gttatctaat tggagatgga acaggacatg gtgatccgca
    13621 agcggaattc ttttcatttg aggcctgtga atatcgccgt catttccttg cctattcacc
    13681 agactatgca atcatgacca atatcgattt tgatcatccg gattattata caagtatcga
    13741 cgatgtattt acagctttcc aaacaatggc tggacaagtg aaaaaagcta tttttgcgta
    13801 tggtgacgat gcttatttac gcaaattaaa agcaaatgtg ccgatttatt attatggtgt
    13861 cacagaaaac gatgatatcc aagcacgaaa catcgaacgc acaacttctg gttctgcttt
    13921 tgatgtctat catggggatg aatttgttgg gcacttcact gtaccagcat tcggtaaaca
    13981 caatatctta aatgctttag gtgttattgc agtagcttat ttcgaaaaac tggatctgaa
    14041 agaagttgca gaagaaatgc tgactttccc aggagtaaaa cgtcgattca gtgaaaagat
    14101 cgtagcagac atgaccgtag tcgatgatta tgcgcatcac cctgcagaga tcaaagcaac
    14161 gattgatggc gcacgccaaa aatatccaga taaagaaata attgcagttt tccaacccca
    14221 tacgtttacg cgtacgattg cattgatgga tgaatttgca gaagcacttg atttagctga
    14281 taaagtttac ttatgcgata tttttggttc ggctcgggaa gaacaaggaa acgttaagat
    14341 tgaagacctt ggagcgaaaa tcaaaaaagg tggagaagtc atcaaagaaa ataatgtatc
    14401 tccattgtta gattatcatg atgcagtagt aatcttcatg ggtgctggag atgttcaaaa
    14461 atttgaacaa gcgtatgaaa aacttttaag cagcacgacg aaaaatgtac tgtaatacaa
    14521 ttactgcagt gtccttataa aaatagaaag agggggagtg gcaaaaatct tgccaagccc
    14581 ccttttttgc aacttatgat aaacggtgtt caaaagcttg catctgcggt aataagccca
    14641 atcaaatcaa aaacatgaga agctgttttt tcttggctgt tcttattatt tgatgcagga
    14701 cagctttttc acgacctctg taaactatag gaatctgtta aatcaaggga gcagaacttg
    14761 ccttttacgc tacttttggt acaataatgt atgattaaaa ataaactgga gggtttctat
    14821 cttgaacata ggtaagccga gaaaactagg aaaaacaata aatgaaatcg aggaaggcga
    14881 ctcgttatcc ttaacagaat ctattgaaga taaccagctt ttgctgtatt tgggattgac
    14941 gaatgatgca aatcctttgt atatccaaca tgactttgca caaaaaacag aatatcaaca
    15001 gccaatcgtt ccatcagtga tgctgatggg gatcatcaca agtgcaattt caaagcatct
    15061 tcctggacca ggatcacatg ttgtcaattt ttctgtcaat tttattgaac cggttttcca
    15121 ttatgaaaca ctgacttttc agtttgaggt cataaaagta gataagatga aggatgtggt
    15181 gacgatttct gtagaagcgg agaatacgaa cgaagatcgt gtgttggatg ctgtcgttat
    15241 ggtccaaccg ccacaagttc ctgaattgga aatagcaatc gaaagtgaag gtgaattgaa
    15301 tgaataatcc aagtacatca atgtcaggta tcaatcgttt ttatgcaaaa gtttatggat
    15361 ttttaggtat gggacttgcc cttagtgcag tcacttctta cttggctctt tgggtatttc
    15421 ctttgcaatt agcaactttt atcaataatt ttccactagg ctttgtgggt ctgtggatcg
    15481 ttgaactgat tttagtaatg gttctaggcg taaaagcaca aaagaatccg agcttagcaa
    15541 tcggtggatt tattgcctac tctcttttga atggcataac attagcggtt actcttgcat
    15601 actacgatat tggaacagta acgcaagctt tcttgacagc tactttgatg ttcatgggga
    15661 tgtctgttgt cggagtaaca acaaaaagag atcttagcgg ggttggaaga gcaggacagg
    15721 cagctttaat cggagtgatc attgcactag tcttgaacat cttcattttg agaagtagcg
    15781 tagttgagct gttcatctcc ctactgttag tcgtcatctt tgcagggatt acagcttatg
    15841 ataaccaaag catccgtaat atctatgtcc agacaaacgg aacagcacat agtggaattg
    15901 ctgtattcat ggcattgaag ctgtatttgg actttatcaa cttgttcttg gcgtttctga
    15961 gaatctttgg acggaacaac taaaaaagaa aaaaattcat cagttggggc tataccgaat
    16021 tatttggtat ggtcccgctt tttcttttcg cattccgcag gattctttgt tagaatgaat
    16081 aagaacttta cagtaaggag ttaagaagat gacaaaaaat aaattattac tcgttgatgg
    16141 gaacagtgtg gcttttcgcg cattctttgc gcttcacaat tctcttgaac gtttcaaaaa
    16201 tagaaacggt cttcatacaa atgcaatcta tgcattcaat acgatgtttg aaaatgttat
    16261 gcaaaaagag caaccgactc atgttctggt tgcgttcgat gcaggaaaaa cgacttttcg
    16321 gacagaaatg tatgcggagt acaaaggtgg aagatccaaa acacctggcg aattcaaaga
    16381 acaaatgcca tatatacgtg atttgttgac aggactaggg gtacagtatt acgaattgcc
    16441 caattatgaa gcagatgata ttatcggtac tttggcagaa aaagtagaca aagatcaatt
    16501 tgatgtcgtc gtgctttcag gtgatcggga tttgactcaa ttagctagta aagaagtaaa
    16561 agtggatatc actgtaaaag gtgtcagcga tatcgaaagc tatacaccag aacatgtagc
    16621 ggaaaaatat gatgggttga cgccaaaaca gattattgac atgaagggac tagccggaga
    16681 tgcctctgac aatatccccg gtgtgactaa aatcggtgaa aaaacagcta tcaagctatt
    16741 gaaacaatat ggctcagtcg aaggaattta tgaacatatc gatgaaatga agcaaagcaa
    16801 aatgaaagaa aatctgataa atgacaaaga gcaggctttc ttatcgaaaa aattggcgac
    16861 catcaatact tcagcgcctg tggatgtctc tatcgactca ttgaagtatg aagggaaaaa
    16921 tctcgataaa ctcgttccgt tttataaaga aatggatttc aatcagttcc tttctaaatt
    16981 gaatatcgta gaagaagaag taaaaatgga tgatattttg tttgaagtcg ttcatgaatt
    17041 caaagaggaa atgtttacta cggatatggc gttgtacgtg gaaatgatgg gcgacaatta
    17101 tcatacagag gaaatcgtcg gagtagcgtg ggggacagaa aagaaaattt atgtcacgaa
    17161 cgatctatct gtattcgaaa accgagcgtt ccattcttgg atcactgatc cgactcggct
    17221 gaaaaaagta tatgatgcga aacgaactta tgttgcttta aaccgctata ctggaaaaac
    17281 gaaaggaatc gattttgatg tcttgctagg tgcatacctt ctcgatacga atgaaaaaag
    17341 cacagatatc gaaggaatag ctgctcatta cggatacaac gatatccaat cagatgaagc
    17401 tgtatacggc aaaggggcga aaaaaggttt accagaagaa gaggaactct tttttgctca
    17461 tttagcgcga aaagtagctg caatcaatgc gttgacacca aaattgagcc aagaactggc
    17521 agaaaaaaac caagaagatc ttttccggaa aatggaactg ccattgtcta tcattttggc
    17581 agagatggaa ataagcggga tcaaagtaga tgcgactcgc ttacaagaaa tgaagggcga
    17641 gttctctgct cgcttaagag agatcgaaca aaaaatctac gaagaagccg gcgaagaatt
    17701 caatttgaat tcaccaaagc aattaggagt gatcttattt gaaaaaatgg gattacccgt
    17761 tatcaaaaaa acaaaaactg gatattccac agccgtagat gtactggaac agcttcgtga
    17821 acaagcacca atcgtagagg atatcctcac ctatcgtcaa attgcaaaaa ttcaatctac
    17881 ctatgtcgag ggactgctga aagtgatcca atcagatgga aaagtgcata cccgttatgt
    17941 ccagacattg acccaaacag gacgattaag ctctgttgat cctaatttgc agaacatccc
    18001 gattcgatta gatgaaggga gaaagatacg tcaggcattt gttcctagag aaaaagactg
    18061 gctgatttat tcttctgact attcacaaat cgagttacgc gtacttgcgc atatctcaaa
    18121 tgatgaacat ttgaaagctg ccttcctaga aggtcaagat atccatgcca gcacagcgat
    18181 gcgtgtattt ggaatcgaaa aggcagagga tgtcacacca aatatgcgta ggcaggcaaa
    18241 agcagtgaat tttggtatcg tgtatggcat ctctgattac ggactttcac aaaatctagg
    18301 aatcagccga aaagcagcac agcaatacat cgatacgtac tttgaaaaat acccaggtgt
    18361 caaagaatat atggaaagaa tcgtacgcga agcaaaagac caaggctacg tcgaaacgct
    18421 gtatcaccgc cgtcgatatc tgccagacat caattcaaga aattacaata tccgttcttt
    18481 tgcggaacga acagctatca atacaccaat ccaaggaagt gctgctgata ttttgaaaat
    18541 cgcgatgatc gaattggata aacgattaaa agaaacaggt cttcaagcta cgatgctgtt
    18601 acaagttcat gatgaacttg tcttcgaggt accggaaaaa gaacttgaat cattagataa
    18661 attggtgaag gaagttatgg aacaagctgt ttctcttcat gtaccactga tcactgacag
    18721 cagttgggga aaaacgtggt acgaagcaaa ataaacattg tttaagacag agcaatataa
    18781 tgaaggtgaa aagaaaaaat gccagaatta ccagaagtag aaaccgttcg taaaggattg
    18841 gaacggttag tagtaggaaa aacgattcaa aaagttcagg tcttgtggcc caagatcatc
    18901 gagcaaccag agacacccat ctttgaggct tctcttgttg gcgaaaccat ccaatccatt
    18961 ggacgtagag ggaagttttt aatttttcat ctcgatcatt gtgaactgat ctcacacttg
    19021 cgaatggaag gaaaatatca atttacgaaa gaaaatacac caatcgataa acatacgcat
    19081 gtacttttct tttttgagga tggaagccaa cttcgctaca acgatgtacg aaaatttggt
    19141 cgtatgacaa tcgtcgaaaa aggagcaagt gcaacttacc gaggaatcat gaaattggga
    19201 cctgagcctt tgccagatag cttcttatta gcagatttcg caaatggact gaaaaagtcc
    19261 cacaaagcaa tcaagccatt gctgctagac caacgtctag tgactggtct aggtaatatt
    19321 tatgtagatg aagcattatg ggaagcgaag atccatccag aacaaccggc gaacacactg
    19381 cgccccaaag aggtagaaca attacgtcta tcgatcattg atgttttgga tcgtgcaata
    19441 gaagccggag gtaccacgat tcgcagttat ttgaatgcat taggagaatc aggcggattt
    19501 caagtagcac tgcatgtcta tcagcaaact ggcaaaccat gtatacgttg tggaacgccg
    19561 atcgtgaaaa caaaagtggc acaaaggggg acgcactatt gtccgaattg tcaaaggcta
    19621 aaaatcgcaa agtaggattt gttttaggtt tgacgggtgg aatagctacc ggtaaaagta
    19681 cggcagccaa agtctttcag tctcatggat ttcctttgat cgatggcgat gtgattgcca
    19741 gagaaactgt tgagcctgga acgcttgctc tgaggaaaat tgtatcagtg tttggccaag
    19801 aggtattgca gcctgatggg caactagatc gagggaaact tgggatgatt gtttttccat
    19861 caaaggaaaa acggcaaaaa cttgatcagc tattagatcc gtttatccga aaagcgataa
    19921 aagatcaaat cgcctctcta agttccaatc atcctttagt aattgtagat atcccattgc
    19981 tctacgaagg tcattatgac cactatatgg atgcagtagc tgtcgtttat actacgccag
    20041 aaactcagct tcagcgtttg atgaaacgta atcaactgac gctagaacaa gcgcagcaga
    20101 gaattagtag tcaacttcca atcgaagaaa aaaagcagcg tgcggatatt ttgttcgaca
    20161 acaatggaac aaaagaaaaa cttgtgggac aaatcgaaaa ttggcttttt gctaatcgct
    20221 ttctttgagt atctgtgtca attttgctat cctgagtata tagaaagtga gggatagcga
    20281 tgggatcatt aaaaaatcaa aaggataaag tcgtaggtaa cgcaaaagaa aaaatcggcg
    20341 agatgctcaa taaagaaaat ctaatcgatg aaggtcgtac gcaatcagaa acagcagaag
    20401 aaaaagaaaa gcagtaccaa gcaagaatcg atgaaataga agaccagcag gcagaagaag
    20461 aagcgaagcg gcaagatttg actcaagaac gaaaaaatcc gacacctgat cgtagtaaaa
    20521 caccgctccc agaaagtgac cacattcccg atgagcaaaa aatcgaggaa cagcgaatga
    20581 aacactatac aggaatcgaa gagaagttat aaaatagtaa aaaatcgaga tgtgacttga
    20641 agcagatgag aaggtgttca tctgcttcaa gttttttgtg ctagatgact aaatcagctt
    20701 ttgtgtaagt tatttctcag taatcaaggt gatcagtatt ggaaaattga aatttagtaa
    20761 ggacagggga cacaattacg catgaaagta gaaaaaattg ttcttatatc cgtgtttttt
    20821 gggtaggaca gtcgcgtttg tgatttgttt cgtgttataa tacaactagt tgtaaagaaa
    20881 gacacatcct ttatataaaa tgcgatgcaa gaggtgagac aaaatgagat gtcccagatg
    20941 tcaacataat aattcacgag taatcgacag ccgtcaagca gatgatggac gtgcgatccg
    21001 tcgccgtcgc gaatgtgaga attgttcgtt ccgattcact acatttgaac gaattgaagc
    21061 tgctccgtta ttagtaatca agaaaaacgg ggaacgcgaa gagttcaatc gcgataaaat
    21121 tttaagagga ctcatccgtt cagcagaaaa aagacctgta gctatggaac aaatggaaca
    21181 aatcgtcaac catgtcgaaa accgcgtacg cagtctcgga gaaaacgaag tatcgacgaa
    21241 tctaattggt gaatatgtga tggaagattt agttgattta gacgaaatcg cttatattcg
    21301 ttttgcaagt gtttatcgcc agttcaaaga tatgtctgtt ttcttaaaag agttgcaaga
    21361 tatcgtggat aaagcaaaag aaaataataa agagaataat aaagaaaaca attaagaaac
    21421 aaaaaggagg catttccttg gaaaatgctt ggaaagagct tcaaccaaaa aatatttacc
    21481 aaggaagaaa agcggctccg ctgagagaag acagcaagaa cgccttgctg tatctttatc
    21541 agccactaat cggcggagaa gccttgagta tctatttcac cctgttatca gaaatctctc
    21601 aagaatctgg caaaggtcct gaagggatgc atgcagatct gcttagtagt ctaggctgcg
    21661 gtatcccgca attttatgat gcaagaaaaa agctagaagg aatcggctta ctggatgttt
    21721 attttaaaga agatagtgat ctgggacctc gttttattta tgagctgtta gaaccactca
    21781 ttcctaaagc atttttcaaa gactctgttc tggcttttct tcttctggaa aaagttggtg
    21841 aacgacgatt ccagaagctt acccaattct ttgaacctaa aaggcataca gcagagggat
    21901 atcaaaaaat cacaaaaaaa tttttagatg tttatcgctt caatgaagca gtgtacgctg
    21961 ctaatcaaga aaacatcgaa tcgctgaata aatcttttga agaatctgaa tcagtagcat
    22021 tacttgaagc agattcgaca ttcgattggc agtttttgaa tgattggctg gcaaaaaaac
    22081 atattgcaag tcttgatgat ccaatcatca aacaagtcga catgtatcat cagctttacg
    22141 gtttcgatga attgacactt ggcgaactga tcagtcaatc ttatgacttt agtgaacaaa
    22201 aagtatctga aaaagaactg caaaaagcca ttttggcaat gcagagacgt ccggtgaagc
    22261 aaacaaaaga aacagttgcg gtttctgaaa acagtaatga accctcgtca aacgaacatt
    22321 tgacaaacgc agcgcttcag ctgataaaag aagcacagag cattccaccg atgaaatatc
    22381 tggaagcaat caagtcagaa aaaggcggat atgtttctaa acaagaaaac tggttactgc
    22441 aagatcttgt ttctcaatca ggtctttcca gtagcgtgat caatgttttg ctgaattatg
    22501 tactagtgat caagaataat gctagcttaa atgccagtta tgtaaataca gtggcaaatg
    22561 aatgggcaca aaagaaaatc gccacagcag aagaagcgat ccagcacatt cggcaaataa
    22621 gtaatcaagc aaaacaatca aaacaaaaga agcaaacaaa ttatcaaact ggcaagcgaa
    22681 atgttcgacg ggaaaagctt cctgattggg tcaaccagcc aaaagatgaa aaacagatca
    22741 gcagcgagaa aaaagcagag attgaccgcc gttttaaaga atacctggca aaaaaggagg
    22801 gtgatatcta gtggaagacg taggcaaaga attgaagagg atcatcagca aacgcaatta
    22861 tcaagaaaag tatgctgaaa tgatcgctga agtcttaaat gatgcggatg ttcaagcttt
    22921 tctaagcgca caccaagaag aattgacaca agcggatatt gaaaaaagtt acgctaaatt
    22981 gtatgaattc gtgcaagaaa agcgtaaata tcaaaaaaac gatccaacga tgatcgctcc
    23041 cggctatgag ccgaagctga cgttgaattt tcattatgtg gatgtcactt atgtaccaac
    23101 ggaagcattg ttagcacggc aaagacaaga agaaatcaga agccgagtaa aagcaatgga
    23161 tatgccaaaa gatattcaat cggcttcttt tgaaaacttt gaacgtacag atggacgagg
    23221 atatgcgagc ttagaagccc tagattttgt agagaaatat actgctgatc caaaagggta
    23281 tcataaagga ctgtatctag taggaagttt tggtattgga aaaacatatt tattaggagc
    23341 aacagcgaga gaattagcga ttgctggatt caccacgacg ctagtccatt ttccgacatt
    23401 tgccgttgag atgaaacagg caatcggaaa agatcaagtg gcagaaaagt tagatgcagt
    23461 gaaacgttca cctattttga tgatcgatga cattggtgca gatgcgatga gtagttggat
    23521 acgagacgaa gtattcggtg ttatccttca atatcggatg caggaacagt taccaacctt
    23581 cttctcatcg aattttacaa tggatgaatt ggaacagcat ttgtccgtca ctcaacgtgg
    23641 agatgaagag ccgctaaaag cgaaacggat aatggaacgc atacgttatt tgacaaaaga
    23701 aatcgaaatg actggtcgca accgacgcaa tggttgaaca gttgacaagt ccaactgaca
    23761 tttgacctag tagtaaaagc aggtcagcga atcattatat ggacagaaat gaccggagac
    23821 aatcaccgca acaagtaatg cagaaactta aacggaggat tttttatgag ggctattttt
    23881 tctagtatat ctgtagttgg tctatttttt cttttagcag gctgcggtag cgcagatagc
    23941 aacacaggtt ctgttgattc gattgatgcg ggtcaaacag taaaaacaag cagtacgaaa
    24001 acggagagac aaagcatatt tgtcggaacg attgaaagta tcactcaagt agaagcagaa
    24061 gaagaaacgc ttcagttgaa actcgtcgat gtcatggcca aagaagatcc agcgaatatg
    24121 ggaacgtcat tcagcaatga cggagtgatc ttaaatgcta ctgctgaaaa aataagcgtg
    24181 gacataaatg aattgaaaat cggtgacaaa gtccaattta cattagttga gatgccgatc
    24241 atgacgatgt ctatcccacc gcaagttcct ggagattcga ttattgatgt ttcattgaac
    24301 aaataaccaa taacattttt tcaaaaataa gaaaatgttg ttttatagaa cgaaaaggta
    24361 tattttttaa ggagatatgg gaattttttt attcctagtc tccttatttt atttggaaaa
    24421 tgctataatt atctagaagg agtgaagcta tgaaccattt agatttatct cagcgcttag
    24481 ccgcagtggg tgactttgtc cctgaatccg ctcgtttagc agacattgga tcagatcacg
    24541 cttacttacc cgttgcattg atattaagag gaaaaatcga atatgcagtt gctggtgaag
    24601 tcgttcaagg tccttatgaa tcagcacgta agcaagtcaa aaaagatgga ttagaagacc
    24661 gtatcaccgt acgccttgca aatggtctag atgctatcca gccacaagat ggtattacag
    24721 ctgtcacgat tgcgggtatg ggaggttcac tgatccgaga tatcctagaa gctggcaagt
    24781 tgaatcaacg cttaagcgga caagaacgtt tgatccttca gccaaacatc ggagagcgta
    24841 cattacgatc ttggctgcaa gaaaatcagt ataaaatcca atcagaaaaa atacttgaag
    24901 aaaataaaaa aatatatgaa atcattgtag ccgaaaaaga acaaaaacca gttacttaca
    24961 atgaaatgga gctgatgttc gggccatttc tgcttgaaga gaaaagtgag atcttcaaat
    25021 caaaatggac aagagagctt caacaaagaa aagctatccg tgaacagctc aaacaagcag
    25081 ctaatcaaga ggcacgtcaa aaacaaatcg agcaggaaat ccaaatgatt gaggaggttt
    25141 taaagccatg acaatcagcg gacgcacttt catccaaaag tttgaaagct attgtcctca
    25201 gtggctagct gaagaaggag acccagtcgg actgcatatc ggaacattgg ataagccaat
    25261 ccaacgagta atgatgacat tagacgttcg tccagaagtg gtcgaagaag caatcaagaa
    25321 aaaaatcgat ttgctgattg ctaaacatcc tccaatcttt cgtcctgtaa aacggctggt
    25381 tactgatcag ccacaagaaa aaatgtatgc agatttgttg aaacatgata ttgccgtcta
    25441 tgcagcacac acgaacatgg atattatttg ggatggactg aatgactggt tttgtgaact
    25501 tctcggtatt gaagtggaga gttatttagt aaagactcat gagattcatt ataaaaaact
    25561 ggccgtttat gtacctgtgg atcatgcaca gaaaatgcgt gaagtattag ctgcagctgg
    25621 tgctggtaca caaggtgatt ataccggtac aagttttacc tcgattggac acggtcgatt
    25681 tactccggaa gctggtgcac aaccagcgat tgggaaagta gggaagacag aacaagttca
    25741 agaggcaaaa gttgaggtta ttttgccgga aactatcgaa aaacaagtga ttcaagccat
    25801 gcggtcagct catccttatg aggaacctgc ttatgatctt ttcgctatag atgaaccagt
    25861 cgaaatgttt gggttaggac gagtaggtga attgccgcaa gaaatttcta tagaggcatt
    25921 tgtagaacaa gtaaaagaag cgttccaact agatggactg agaatagtcc agccaaaaaa
    25981 tgcaaaatcc tctgtgaagc gcattgcgat ttgcggtgga agcggtgaaa aattttatcc
    26041 gcaagcaatc gcccaaagag cagatgtcta tatcacggga gatatctatt atcatacggc
    26101 tcatgatatg caaagcgctg ggttgattgc aattgatccc ggtcattata ttgaatcgtt
    26161 atgcaagcaa cgatttatcg agaaatttga atcttggaaa caagaagaaa attgggatat
    26221 taactttttc gtttctgaaa caaatacaaa cccatttcaa tttaattaaa aggagagaat
    26281 actatgtacg aaaatctttt gccacgtttt ttacgatatg tcaaaacaga aacacgctcc
    26341 gatgcaacaa gcaaaacgac tccatcgact cagacacaag ttgcttttgc gcaagaattg
    26401 aaaaaagaat tagaagagtt aggcttagct gatgttttct ataatgaaga taacggattc
    26461 gttatgggaa cattaccaag caatgttgat catgaagtgc gttccattgg atttatttcc
    26521 cacatggata cagcagattt taatgcagta ggagtcaatc cacaaatcat tgaaaactat
    26581 gatggcgagt ctacgatcgt actagatgcg gaagaacgct atacattgaa tacaaaagat
    26641 tttccaaatt tgaaaaatta tgaaggccac acattgatca caacagatgg cagtacatta
    26701 ctgggagcag atgacaaatc agggattgcg gaaatcatga ctgcaatgga gatcttgatc
    26761 aataatcctt ctatccctca cggtaccatc aaagtggctt ttggtcctga tgaagaaatc
    26821 ggtgtcggag cggataaatt cgatgttgag caattcgatg tagattttgc ttatacagtc
    26881 gatggtggtc ctttaggtga gttgcagtat gaaacgttta gtgctgctca agcaaatatt
    26941 acgatccaag ggaaaaatgt acatccaggg acggcaaaag atacaatgat caatgctcta
    27001 cagttagcaa tcgattttca taatcagctt ccagccgatg aagttccaga aaaaacggaa
    27061 ggatacgaag gtttcttcca tttgatggca ttggatggga atcctgaaga agcttctatg
    27121 agttatatca ttcgcgatca tgatcgtgaa aaattcgaag cacgcaaagc acaaatcaca
    27181 catatccaag aagagttgaa tcagcgattt gatcaagaac gaatcaaagt agatatgtat
    27241 gatcaatatt acaacatgaa agaaatcatt gaaaaagata tgagcatcgt ggaattagcg
    27301 aaacaagcaa tgatcgagct tggtatctct ccagtgatcg aaccagttcg tggaggaaca
    27361 gatggttcaa aaatctctta catgggtatt ccgacgccaa atctatttgc cggaggagaa
    27421 aatatgcacg gacgattcga atttgtttct ttacaagtaa tggaaaaagc aacagacgtg
    27481 attgtaaaaa ttgcagaatt gaacacaaag agttaaaatc gaaaaagaac agcttatgac
    27541 aaggcgttcg tcccaatgat ggaatgtcat ctgtctaagg ctaaagggca ggacaatgga
    27601 attggttgtc ccgccctctt ttttgaagag taaataggag gtaaagaatg gaaaagctgc
    27661 tagtttttta taacaaaagt tcagggaaag atgagggtga gaaattagca cgctggtttc
    27721 aagattatgt aaaagaaaag cagccagaat tatatgtaga actagctgaa actggcccat
    27781 cgattgatga tgcggaatta gtcaagaaag cagaagccat agaagctgat actttagtaa
    27841 ttataggtgg agacggcacg attcatcata tcgtccaagc gttccaaaaa acattatctc
    27901 aataccatgt cggattactt ccaggtggaa ctgtcaacaa ccttgcacgt gttcttgaga
    27961 ttcccctcaa aaaagaagaa gctgctgacg tgatcctgga aggcaatgta cggaaaatag
    28021 actatggtca agtcaatgat gaagtcatta tctctacact gacaatcgga atcttagcag
    28081 atacagcagt ttggatcagt caagaagaaa aacagcgtta cggctcgtgg atctttatca
    28141 agaagttttt taagttattg ctgaagaaga aaaaatatca tttggattta gaaacagacg
    28201 aggagcattg gaaaggaaaa tcccaactgt tgacagtcac gatgtctaac tccgtgggcg
    28261 gttttacaaa ttttgacgac tcagcgaccc tagatgatgg aaaatttcat gtaacgatcg
    28321 taccttcctt agatattttc cgatttattt tttatttgcc tagaatcatg agaggcaaat
    28381 tctatacgat ccccggcatt acttatttca cagccaaacg catgaaaatc caagcgcagg
    28441 aaaaatctgt gggcactcga acggatggag acacgacaga tgatcttcca gttgaattat
    28501 ctgttgtatc aaaaggatta acagtttatt caccaaagaa agaagaaaaa gcttagaaat
    28561 agtagttaac agaaagttgg aagaagagta atggatgtat tgttacacaa tcctttgtgg
    28621 ttttaccttt tcattgtgaa tttttactta ttttgtctga tggggtatga taaacatcag
    28681 gctagaacta gcggctggcg tgttcctgag aataatttga tatttgtcag cctgttaggc
    28741 ggtggtttgg gaggattgat ctctcgaaaa gttttccatc ataaaactcg gaaaaagaag
    28801 tttactatag gattcgctgc aggtgtactt gttgatttga ttctcattta ttttttccat
    28861 taaggagcag gagatgtcgt ctaaaggaac gaaaactaaa atcattctga atctgctttt
    28921 gctgattgtg atttttgcca ttatttatta tttaatcaat caatcatttg cagatatctt
    28981 tgccgaattg ctgtctacca gtgttgttgt tttggcagcg gctgttatat tagggacagt
    29041 ttaccaaatc gctgaagggc gctcaatcaa agaaattgct gaacctttcg cgccgaattt
    29101 tacaacgaaa gatgggttct tgacctctag ctatattgcg ttttaccgaa tcgtttcgtt
    29161 tggtacagga acgctgatct cggagattta tttttataac aaaaaaggaa tgaagctatc
    29221 ccagggagca ggggtgacag cactccatat gattatgtac aaactggcag tgatcactta
    29281 tgcattagct ggcttggtca tccaattctc tcttttttat tctaatggtc catcaatgat
    29341 ctggtttatc atcgctggta tccttttgac gatcgtgatt gttgcctttt tattggcgat
    29401 gtccgtcagc ttgaatgttc aaatattttt tgtcagctta tcgaataagt tatttaaaag
    29461 tgagcgtttg cggaaatggg tggatacatg caatcagcag atctactctt taagggaaac
    29521 ggtccaaacc attatccaag acaggactgc gctattgcgg atttatctat ggaatatgtt
    29581 aaaacttgta ttttggtatg tacttcctta tttgattctg attgaaaacc atcctaaaat
    29641 agattttcta ctgaccattt cgtttatcag ctttgcagta gtgctttcag gggttattcc
    29701 tacgcctgct ggtattggtt cctttgaatt tgtctatttg ttattattca gaccagttgt
    29761 tggaacagtt gacgcagttt cttcgctttt actgtatcgt ttcagttcct ttatcttgcc
    29821 atttctctat ggatttgtgt atgtgattgc tgaacggcga agagtgatca aagaagaaat
    29881 aatagaagta aaaaaagaga ataaagaaaa tcaagggtag gtcttttata agatctaccc
    29941 tttttatcaa atcaaagaaa aacgttatgg ataagataat tttacgtttg tttggctctt
    30001 tttttatata catacaatca attttgtttt tttaagattt atataagtcg agaaaaaaag
    30061 tcaaaaaact atgtgtatat tttgaccaaa attgaccaaa gcgatataat agtttttgta
    30121 aagatcaaag aaataagtga tcttaccttt aattaggagg gtatacctgt atgaatattg
    30181 agaaaatgac tacgacgctt caagaagcga ttgctgaagc tcaacagatt gcggtcactc
    30241 gaaaacatca agatatcgac attgcccatg tatggaaaat ctttttacaa tctaatcatt
    30301 ttggtcgaaa tttctatacg gatgccggat tggatgtcga atcttttgaa catgaaattg
    30361 atcgtctact ggatgagtat ccagttgttt ctggtggaaa cgtccaatat ggacaaaacc
    30421 tcagccagaa tttctttcga ttattgaatg aagcagacca aatacgtgaa agcttcggcg
    30481 acgagtttct ttcaacggaa gtcgttattt tagcgttgat gaaattaaaa aattatccgt
    30541 taactgttta tttgaataaa aacggattat ctgaaaaaga attgcgtaaa aacatcgaag
    30601 agatgagagg aggagaaaga gtgacctcac aaaaccaaga agaacaatac aaagcattag
    30661 aaaaatacgg cgttgattta gtacagcaag tcaaaagcgg aaaaatggat ccaatcatcg
    30721 gtcgtgatga agaaatccgt gatgtcatcc gtattctttc acgaaaaaca aaaaataatc
    30781 ctgttctgat aggagaaccc ggtgtaggga aaacggcaat cgttgaaggg cttgctcaac
    30841 gtatcgtacg caaagatgtg cctgaaaatt taaaagataa aacgattttt tcattagata
    30901 tgggtgcatt gatcgctgga gcaaaattcc gtggtgaatt tgaagaaaga ctaaaagcag
    30961 tcttgaaaga agtcaaaaaa agtgatggac gtatcctctt gttcatcgat gaaatccaca
    31021 atatcgtagg ggcaggaaaa acagaaggaa gtatggatgc cggaaatctg ttgaaaccaa
    31081 tgcttgctcg cggtgaatta catttgatcg gtgccacaac tttagatgag taccgtcaat
    31141 atatggaaaa agacaaagcg ttggaacgtc gctttcaaaa ggtattagtc aaagaaccaa
    31201 cagtggaaga tacgatcagt attctgcgtg gattaaaaga acgttttgag atccaccatg
    31261 gtgttaacat ccatgacaac gcattagtag cagcagctac tttatctgac cgttatatta
    31321 ctgatcggtt cttaccggac aaagcaatcg atttgatcga tgaagccagt gcaacgattc
    31381 gggtagaaat gaactctatg ccaacggaat tagatcaagt tactagacgt ttgatgcagt
    31441 tggaaatcga agaagctgca ctgaaaaaag aatcagatga tgcaagtaaa aaacgcttga
    31501 aaaatttgca agaagaatta gctgaacttc gtgaagaagc aaatgcgatg aagatgcagt
    31561 gggaaacaga aaaagaagaa gtcaattctg tttcagcaaa acgtgctgaa atcgataaag
    31621 caaaacacga attagaagat gcagaaaata actatgattt agaacgcgct gctgtattgc
    31681 gtcatggtac gatacctcaa ttagaaaaag aattgaagga attagaagct aaagcaaaag
    31741 acagcgagat taagatggtt caagagtccg ttaccgaaaa tgagattgct caagtcgttg
    31801 gcagattaac gggtatcccc gtaacgaaac ttgtagaagg tgaacgagaa aaactaatta
    31861 aattgaatga aacacttcat aaacgagtga ttggtcaaga tgaagcagtt gatgcggtca
    31921 gtgacgcggt aattcgttca cgggctggat tgcaagaccc aaatcgtcct ctaggttctt
    31981 tccttttcct aggaccaact ggtgtcggaa aaaccgaatt agcgaaagcg ttagctgaga
    32041 acttgtttga ctcagaagat catatggtac ggatcgatat gagtgaatat atggaaaaac
    32101 atgctgtgtc tcgtctagtc ggagctcctc caggctatgt aggttacgaa gaaggtggtc
    32161 aattaacgga agctgtcaga cgaaatcctt atacaatcgt cttgttggat gaaatcgaaa
    32221 aagcgcatcc cgatgtcttc aatatcttgt tacaagtcct agatgacgga cgcttgactg
    32281 attcaaaagg gcgagtagta gatttcaaaa atacggttct gatcatgacc agcaatatcg
    32341 gttcacagtt actgctggaa ggcgtgactg ctgatggaac gattccagaa gcagtggctg
    32401 aacaagtcaa cacgctatta cgtggaaact tcaaaccaga attcttgaac cgaatcgacg
    32461 acacgatttt atttacacca ttgagcctag acaacgtgaa aggaatcgtt gacaaaatgg
    32521 tggcgcaatt ggcacaacgt ctggaacatc aagaaatcct gctgacaatc agtgatgaag
    32581 ccaaaacgtg gattgctgaa aatgcttatg aaccagcata tggtgcaaga ccattgaaac
    32641 gatttatcac taaggaagta gaaacaccac tagctaaaga aatcgttgca ggacatgtta
    32701 tgcctaaatc aaaagtaacg attactttac ttgatggaca acttcatttc aaaacagaag
    32761 agctagaaga aatcgtctaa tcttccattg agactataaa agaaaaaagg ggtctgacac
    32821 aactagtgtc agacctcctt ttttcaaata aacagtgttc cagaagtagt ttcttcgaaa
    32881 aataagccga aatttcttga agctgcccgc ttctgtcaca acctctttta ttaggtattt
    32941 ttcacttttt ctaatttata actttcaaag taacgctcat cttttttact ttgagaccat
    33001 gcaaacaatc ccattaaggc agcacctatc gtatttgtca gcaagtcgcc catcgtatcc
    33061 atcaatgctg ctcgtccgac aaacagtgtg ccatcagaag cagcaaaacg ttgaagattc
    33121 atgcctaaga actggtcgca taagaattcc cagaactccc aaaacacgcc gcaaagtcca
    33181 gcaaacgcaa agccgaataa gaggaacaac caaggactgg tttttgatat ctcagcatct
    33241 ttcatcaagt aaccaatcaa tccatagcca agagctgtca ggaccattgg actcaccgca
    33301 tgtaagattt tgtcccaaaa agagatgata ctgatcaaat gcatccctgt gcctaaaaag
    33361 acagagatga acaagaaaaa ccagtaaaac aaaacgattg ctgctggtat tttaagtttg
    33421 aaaactttca aaatgacttg tggcatgaaa atcaatgcaa tccctaataa agattccacg
    33481 ataaatgtga ttccttgaga agtcgaatat ttttgtgtga taaattcata aaaattatag
    33541 cagacaacga atacaccaaa agcaagtaaa gctatttgca cctttttgat ttctttaatc
    33601 actgaaagtc cctccatcta aaaatctttt tacttctgaa agcaactcaa tttctgaaga
    33661 aaccactttt ccgttcaatt tgatcaaacc tattgtatat aagttcaggt agtgaaattg
    33721 attttcagct gtttcttgta gtgcagcgat ttttttcggg tgggttccgc cttgctgtcg
    33781 agtatcagta tataagccga tcactgggat gcctttcgca taagccacac cgatttccga
    33841 tgctaccccg gcatcgatcg tcagcccatc tagtaaagca atcattaaat cactagccaa
    33901 cactttttct gtgtcagcaa gagcaatcat tcgactgtct gcataagcag ttttgtcatt
    33961 gattgcttca ttttcttgag gaagatagat cgaaagctca gaagagagct ctctgatttc
    34021 tttaactaac tgttggttat ataacaaatc acttttagca aacattggtg cggcaaaata
    34081 aattttcatc taaacatcat cctttttatc aaaaataatc gctaaagtaa gcttccatgt
    34141 ttggaatgat acgctctagt gacttcagtg tttcttcatc tgtttctaac cgttcgattc
    34201 ttgccaaata agaagcacgg cgataattca tcatcaagca agtcaatgtt tggatatcca
    34261 gtcgaacgga ttttcctata ggttcattta agacacggac ttgtccctgt tcatcccatg
    34321 ttaaagcgaa gacaccatta ttccaaggag cgacaggatc ttcaatgatg aaatgaaaag
    34381 catcagctgt tccaacaaac ggaaaccgtt gaaggaattc ttttacatca acgatccgag
    34441 ccataaaata tggttcgatc tgctctttga tctgactatc ttcaatcaaa aatgctaaag
    34501 gctcattttt ataaatatct ccatgtaccc agtagatcat ggaaaaatgt gcggaaataa
    34561 agttccataa gccatttcga gcttcttgat caagatagaa catttctttt acgtgaaata
    34621 tttcttcagc tacccagtag aacagaacac ctcttggttc atggttgcta tcgtagtaga
    34681 cagcggctgt gcgctcatct tcattttcga aacgccaata ctcttcccaa tgaaaatcac
    34741 tgcggaataa agcaccatgg ttttgttggg caaatttgtc ataaacggaa aatacgtctg
    34801 gatgatcaac tggtaatcgc tcaaccatac cacttactgg gatttgttta ggtagctgtg
    34861 tatctctgat tttaaaggaa agtttatcag acatgatttc ccatccttta cgccgatagt
    34921 aggggatact gtaaggatac aaataagaga tccattgctt attcttgcgc atattatcca
    34981 atgcaacgat aattagatct tgcatcaatc catggttagc atattctgga taagttccaa
    35041 ctccagtcac accacccatt ttataacgtg caccgtgaat attgacttca caaggataga
    35101 tagcgatttg agagatcagt ttattttcgt ggaaccatcc gaacactttc gatacttcca
    35161 aaatcggttt tttggaacgg ataaaagctc gtttattctc aaacccgctt tcctcgatgt
    35221 ctgcttcagt cacttggaac acataggaaa gcaattcatt gaattgatcg atatgttctt
    35281 gagtgaccgg ttttaattca agattttctc taaaatcttt ttgatccatt ttttcatctc
    35341 catttattag cttgataaca gtatagcaaa attctacaaa aaaaacttct atagctgact
    35401 aattaaaaac tctttaaatt actgcttttc gttggtataa tggaaagtgc tgattatatg
    35461 aaaagaggag acgctatgga tataaagaaa atgaaagaac gccaagagca gattcgtaat
    35521 ttttcgatca tcgctcatat cgaccatggg aaatctacat tggccgatcg tattttagaa
    35581 atgacgcaca ctgtgacgtc tcgcgaaatg caagatcagc tgttagactc gatggatttg
    35641 gaacgtgaac gtggaatcac gattaaatta aatgctgtag aactcaatta cacagcgaaa
    35701 aatggagaaa catatatctt tcacttgatt gacaccccag ggcacgtcga cttcacctat
    35761 gaagtctctc gaagccttgc tgcctgtgag ggtgccgttt tagtggtcga tgcagcacaa
    35821 ggaatcgaag cacaaacatt ggccaatgtt tatttagcgt tagacaatga tttggagatc
    35881 ctgccagtca tcaataaaat cgacctaccc gcagcagatc ccgaacgtgt ccgtcaagaa
    35941 atcgaagacg taatcggaat cgatgctagt gaagctgtat tagccagtgc caaatcaggg
    36001 attgggattg aagatattct cgagcagatc gtggaatatg ttcctgcacc aagtggagac
    36061 ttagatgcac cgctaaaagc tttgatcttt gactctattt atgatagtta ccgcggtgtt
    36121 gttctaaatg tccggatcac ggacggtatg gtcaaacccg gagacaaaat caaactgatg
    36181 agtaatggca aaacatttga tgttacagag gtcggggtct tctcgccaaa agcagttgct
    36241 agagactttt tgatggtcgg tgatgtcggt tatatcacag caagtatcaa aactgtccaa
    36301 gatacacgag taggggatac agtaacgtta gcagacaatc ctgccgctga agctttacca
    36361 ggttaccgaa aaatgaatcc gatggtttat tgtggtcttt atccaattga tacttctcgt
    36421 tacaacgatt tgcgggaagc tttagaaaaa ctgcaattga atgatgctgc tttacaattc
    36481 gaaccagaaa cctctcaagc attaggtttt gggttccgct gtggattcct cggacttctt
    36541 catatggatg tcgtccaaga acgcttggaa cgggaattca atctagaatt gatcacgact
    36601 gcaccatccg ttatttacca tgttaataaa acggatggta cgactgctac agtagataac
    36661 ccggcagatt ttcctgaacc tgtaacgatt caggatgtag aagaaccatt cgtcaaagca
    36721 cagatcatgg tcccaaatga ttttgtcggt gcagtaatgg aactttctca acgaaaacgg
    36781 ggagaattca ttacgatgga ttatttagat gattaccgag taaatgtcgt ctataatatt
    36841 ccgctttctg aaattgtctt tgactttttc gacaaattga aatcaagcac gaaaggctat
    36901 gcctcattgg attatgaaat gtctggttat caaaaaagca agttagtgaa gatggacatc
    36961 ttgctgaatg gagaaaaagt cgatgcatta agctttatcg ttcaccgaga ctttgcctat
    37021 gaacgtggaa aagcaatcgt tgaaaaactg aaaaaactaa tcccacgcca acaatttgag
    37081 gtgccaatcc aagcagctat tggacaaaaa atcgttgccc gttcagacat caaagccttg
    37141 cgtaaaaacg tcttggctaa atgttatggt ggagatgttt ctcgtaaacg taaactctta
    37201 gagaaacaaa aagaagggaa gaagcggatg aaacaaatcg gctccgtcga agttccgcaa
    37261 gaagccttca tggccgttct gaaaatggac gaggacgaac cgaagaaata gcaagggttt
    37321 gtttgaaaac agtgtaaaaa ataaaccatg tttacatgga tttgccaccg gtttgccacc
    37381 ggtggt
//
LOCUS       DAFENC010000025        36407 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.025, whole genome shotgun sequence.
ACCESSION   DAFENC010000025
VERSION     DAFENC010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36407
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.025"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            136..309
                     /locus_tag="LP493_001619"
     CDS             136..309
                     /locus_tag="LP493_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133775.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            949..1422
                     /locus_tag="LP493_001620"
     CDS             949..1422
                     /locus_tag="LP493_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBL2133776.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1431..1658
                     /locus_tag="LP493_001621"
     CDS             1431..1658
                     /locus_tag="LP493_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2133777.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            2294..2665
                     /locus_tag="LP493_001622"
     CDS             2294..2665
                     /locus_tag="LP493_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133778.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(2921..3163)
                     /locus_tag="LP493_001623"
     CDS             complement(2921..3163)
                     /locus_tag="LP493_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBL2133779.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(3195..4097)
                     /locus_tag="LP493_001624"
     CDS             complement(3195..4097)
                     /locus_tag="LP493_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBL2133780.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            complement(4110..4298)
                     /locus_tag="LP493_001625"
     CDS             complement(4110..4298)
                     /locus_tag="LP493_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBL2133781.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            complement(4312..4875)
                     /gene="amaP"
                     /locus_tag="LP493_001626"
     CDS             complement(4312..4875)
                     /gene="amaP"
                     /locus_tag="LP493_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBL2133782.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            complement(4913..5806)
                     /locus_tag="LP493_001627"
     CDS             complement(4913..5806)
                     /locus_tag="LP493_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL2133783.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            complement(5884..6807)
                     /locus_tag="LP493_001628"
     CDS             complement(5884..6807)
                     /locus_tag="LP493_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBL2133784.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            complement(6856..7206)
                     /locus_tag="LP493_001629"
     CDS             complement(6856..7206)
                     /locus_tag="LP493_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBL2133785.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            complement(7239..8141)
                     /locus_tag="LP493_001630"
     CDS             complement(7239..8141)
                     /locus_tag="LP493_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBL2133786.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            complement(8134..8991)
                     /locus_tag="LP493_001631"
     CDS             complement(8134..8991)
                     /locus_tag="LP493_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBL2133787.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            9325..10134
                     /locus_tag="LP493_001632"
     CDS             9325..10134
                     /locus_tag="LP493_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL2133788.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            10174..10671
                     /locus_tag="LP493_001633"
     CDS             10174..10671
                     /locus_tag="LP493_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBL2133789.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(11056..11129)
                     /locus_tag="LP493_001634"
     tRNA            complement(11056..11129)
                     /locus_tag="LP493_001634"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11093..11095),aa:Ile,seq:cat)
     gene            11316..11639
                     /locus_tag="LP493_001635"
     CDS             11316..11639
                     /locus_tag="LP493_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133790.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            11803..12057
                     /locus_tag="LP493_001636"
     CDS             11803..12057
                     /locus_tag="LP493_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133791.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            12127..12372
                     /locus_tag="LP493_001637"
     CDS             12127..12372
                     /locus_tag="LP493_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2133792.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            12448..12813
                     /locus_tag="LP493_001638"
     CDS             12448..12813
                     /locus_tag="LP493_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133793.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(12874..13437)
                     /locus_tag="LP493_001639"
     CDS             complement(12874..13437)
                     /locus_tag="LP493_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133794.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(14005..14205)
                     /locus_tag="LP493_001640"
     CDS             complement(14005..14205)
                     /locus_tag="LP493_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL2133795.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
     gene            14601..14750
                     /locus_tag="LP493_001641"
     CDS             14601..14750
                     /locus_tag="LP493_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133796.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            complement(14957..15670)
                     /locus_tag="LP493_001642"
     CDS             complement(14957..15670)
                     /locus_tag="LP493_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBL2133797.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(15663..16748)
                     /gene="uxuA"
                     /locus_tag="LP493_001643"
     CDS             complement(15663..16748)
                     /gene="uxuA"
                     /locus_tag="LP493_001643"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBL2133798.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            complement(16765..17208)
                     /locus_tag="LP493_001644"
     CDS             complement(16765..17208)
                     /locus_tag="LP493_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBL2133799.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            complement(17242..17595)
                     /locus_tag="LP493_001645"
     CDS             complement(17242..17595)
                     /locus_tag="LP493_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133800.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            complement(17707..18108)
                     /locus_tag="LP493_001646"
     CDS             complement(17707..18108)
                     /locus_tag="LP493_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133801.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            complement(18145..18654)
                     /locus_tag="LP493_001647"
     CDS             complement(18145..18654)
                     /locus_tag="LP493_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2133802.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            complement(18676..19533)
                     /locus_tag="LP493_001648"
     CDS             complement(18676..19533)
                     /locus_tag="LP493_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL2133803.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            complement(19551..20384)
                     /locus_tag="LP493_001649"
     CDS             complement(19551..20384)
                     /locus_tag="LP493_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2133804.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIVGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            complement(20398..21195)
                     /locus_tag="LP493_001650"
     CDS             complement(20398..21195)
                     /locus_tag="LP493_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBL2133805.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            complement(21228..21512)
                     /locus_tag="LP493_001651"
     CDS             complement(21228..21512)
                     /locus_tag="LP493_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HBL2133806.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            complement(21509..22510)
                     /locus_tag="LP493_001652"
     CDS             complement(21509..22510)
                     /locus_tag="LP493_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HBL2133807.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALIERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            complement(22512..23579)
                     /gene="gnd"
                     /locus_tag="LP493_001653"
     CDS             complement(22512..23579)
                     /gene="gnd"
                     /locus_tag="LP493_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HBL2133808.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            23578..24426
                     /locus_tag="LP493_001654"
     CDS             23578..24426
                     /locus_tag="LP493_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL2133809.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            25072..25278
                     /locus_tag="LP493_001655"
     CDS             25072..25278
                     /locus_tag="LP493_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HBL2133810.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(25480..26481)
                     /locus_tag="LP493_001656"
     CDS             complement(25480..26481)
                     /locus_tag="LP493_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL2133811.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(26486..28399)
                     /locus_tag="LP493_001657"
     CDS             complement(26486..28399)
                     /locus_tag="LP493_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBL2133812.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            complement(28567..29073)
                     /locus_tag="LP493_001658"
     CDS             complement(28567..29073)
                     /locus_tag="LP493_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBL2133813.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            29233..29673
                     /locus_tag="LP493_001659"
     CDS             29233..29673
                     /locus_tag="LP493_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBL2133814.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            complement(29699..30856)
                     /locus_tag="LP493_001660"
     CDS             complement(29699..30856)
                     /locus_tag="LP493_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2133815.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(30859..31215)
                     /locus_tag="LP493_001661"
     CDS             complement(30859..31215)
                     /locus_tag="LP493_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133816.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            complement(31513..32487)
                     /gene="sgrA"
                     /locus_tag="LP493_001662"
     CDS             complement(31513..32487)
                     /gene="sgrA"
                     /locus_tag="LP493_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HBL2133817.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSEISTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            complement(32683..33522)
                     /locus_tag="LP493_001663"
     CDS             complement(32683..33522)
                     /locus_tag="LP493_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBL2133818.1"
                     /translation="MIRIIRLIGSVLIVFVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            33707..34594
                     /locus_tag="LP493_001664"
     CDS             33707..34594
                     /locus_tag="LP493_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBL2133819.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            complement(35188..35882)
                     /locus_tag="LP493_001665"
                     /pseudo
     CDS             complement(35188..35882)
                     /locus_tag="LP493_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
     gene            complement(35866..36264)
                     /locus_tag="LP493_001666"
     CDS             complement(35866..36264)
                     /locus_tag="LP493_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBL2133820.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
BASE COUNT        10713 a         7219 c         5756 g        12719 t
ORIGIN      
        1 ttttcggaga attaaaaaat acaataaata actttagtta ctttaatgcg ttcttacttt
       61 atttttatat tatcattttt cttattcact tctttggttt atactattct tataaataaa
      121 aacgaggtat gtcctatgat gaaaagattg tactattcat tgatcataac gattggctat
      181 ttgattgtat caaatctagg aaatatggta tttggtatca gtaaagaatt cagttggact
      241 actacattat gggaatctct attctttttc atcttcgtat ttttgttaca aaattatcga
      301 aaaaaataaa catgtgccat ctatctgttg gcacatgttt taggatttat ggtacttttt
      361 attcggcaat ccattttatt tttctacttc ttcttaatac ctctaacact tttgatttat
      421 aaactaatcc aatgcatcta cttgcgctta ttaagctatt tcagctagat agtaccaccc
      481 catgcgtcaa tgcttgattt tccttttgta taacattgta taagcaataa aggacaaata
      541 agtggtgatt acaccaaacc attgaataag aaaaattctg atacgtaaat aaacatgaac
      601 ttgaaaaaat taatgaatcg gttagctact acgtagttgt cttttttctc atacagttct
      661 gttaacttac acttctcttc gctagataat aaaaaatcct ccaactgtat tgtccaatat
      721 aatcccaggc atctaaacta gcattataga agagacacac atagaatcta aaataactgg
      781 ttttaaatgt ttcttacaat caaaaaaagc tgttaaatgc actccacacc ttcatactct
      841 atcatttttt ataaacgata tatttttatt gtttttcgat aaaaaatagt tgttttacaa
      901 taattattct gctatatttt agctatcaaa gataaaagag ggataaaaat gaaatttaaa
      961 acattgctat taaaatttgt cgttttaggt ataagtgccg tatttatttt gttcggcgta
     1021 cttttttata ctcagatcgc tacaagcgaa aaaggattca attttgattg gcagaccaca
     1081 ttatttgttt ctgtcattta ctttgccctt ctcctaggga tcgttattgc ttatttctta
     1141 ttgaaactat tgaaaaaaat cgaagataac caagcttttt ccactcaaag cttaaacata
     1201 ctaaaaaaaa tcgaacgaac cattttgttt attggtttcg ccttttttgg cttacttcct
     1261 aaatttatga aagtagcgga tttagacgat gctccaggtt tgatgttggt aggaatcgct
     1321 gtcgtattca ttccttttgc agtatacaca ttaacaagcg tgctggaaaa actgcttgaa
     1381 catgcgattt tacttaagac agatcatgat ttgacagtgt gaggtgcgac atggcaatta
     1441 tcgttaattt agatgtagta ttagctcaaa aaaaaatgag tgtgactgaa ttgagtgaga
     1501 aagtgggcat tacgatggca aacatctcta ttctaaaaaa tggaaaagca aaagccatcc
     1561 gtttttccac tctcgaaaaa atctgccaag ttttggagtg tcaaccaggt gatttgttga
     1621 cctataaaaa tgactcgaat actataccag aagaataaaa taaagtagaa caaacagtaa
     1681 ataaaaaata atctgaatga tagatgtgtg agacttttag aagttattta cgtctattat
     1741 tcagattttt tatttcgatt gaataccgtt ttatctataa ataagatatg tactgactca
     1801 tacaaagggg gccttttctt ctccatgtac tatcactttt cctgatacaa ctggtttcct
     1861 gttacgttgt agttggatct gcttttagta taatacttta ttcattccac cagactgata
     1921 gcagtttgag cagtctaaat aatcatgtag tattacaggc cattctgttt cataccttga
     1981 agtgcttaaa acttcagcta atggcccatt gtgttaactc ttactccatt cttttttagt
     2041 aagctcccat atatactgta aagccttcta tatattatgt catgttgctt tttaacattt
     2101 actatgtagt tttgataaaa tgatttgaat aacagtgatg gacaattctt ttttattttt
     2161 aacattattt tgataataat gattatttat ttaaaaatac attagataac atttgttacg
     2221 acacgaaaaa gcttcacaaa caaatatcgt tattttaaaa tgagggcgaa ctcacacaat
     2281 taggaggaat agtatgccat ttattgttta cttttttctt tcattactcg tgatctatat
     2341 tccattacca acatttttcc tgctcgtcaa tcgtctagca gagcaacatg atacgattgc
     2401 tgctcttacg aaactttgtt tacttctatt tgtttgtcta gattacttta cgagctatta
     2461 ttggctaaaa cagacaagag taaaaaagag atattatttc ttccttgtct ttttcaatct
     2521 ctttgagttt ctgatccatt gctttttact tcatcagtat catacgatcc atttgtggat
     2581 catctgggtt ttcaaagtgg tcgtattatt ttgtatgttc acctttccta tctcaagaaa
     2641 atttagggag gcattgtttt attaaagaag cttctctgta tcaataaaga cacatttaag
     2701 gaaaaacttt taaaaatcta attgggaatt tgcccgcata aataagaggc tgtgacaaaa
     2761 gtcttgtcac agcctcttat tccgtataaa cagtgttcaa aagcttgcat cttcgataat
     2821 atgcccaacc aaatgaaaaa tatgagaagc tatttttgtt tggctgttct tattacttga
     2881 tgaagaacag ctttttcacg acctcttttt aaaagtcttt ttacagtttt cgagcaaaga
     2941 atgatacgat tagtactaaa atgatggcac caatcaatga tggcacgatt gccattcctg
     3001 caatacttgg tccccaagaa cctaataatg cttgaccaag tgctgatcca actaaacctg
     3061 ctacgacatt tgcaataatc cccatcgaag aacctttatt cgtgattgct cctgcaattg
     3121 ctccgataat tcctccgacg ataagtgacc aaataaatcc catgtttcgt tcctcctaat
     3181 gttttacttc cttattactg aacccgtggt tctgtatttt cttttacttt ttgtgcgccg
     3241 cttccagctg ctgattttac tttatctgtt tgattcgaag caaattcacc ggtttttttc
     3301 gctgcgtcag ttactttgtc ttgcaccgtt tcttgatctt tttcaaattc ttcttttgtt
     3361 ttgatgtcca ctacgttagc gttgacttcg atcacttcta aatgtgtcat attttttact
     3421 tctttgccga ttacttcttg catttcttca aagatttttt cgatatcttt gccatattcc
     3481 acaatgacat ccatatcaac tgctacttgt tttttaccga cttctgtttc gatcccagcc
     3541 gttacattat ctgtattcac aagttttcct gccacattag agaagaaacc accgtttgca
     3601 gataataaac cgtctacttg ttcaattgcg attccgatga ttttttgcac aactttatct
     3661 tcataattca gctcaccgcg cattgaatct tcctgttcag aatcatgctt tccttggtta
     3721 tttgtatgat cagaaccaag ttttccttgt ccgtttgtgt ggtcagaact aagtttttct
     3781 tgtgctttcg catggtcaga aggatgtttt tgctcttcca caggtttaga aggatcgatt
     3841 gcatcatgtt gttctggaac tttagattct ggagttcctg gatgatgagg tgcatgcttt
     3901 tctgcatcat gtttcttctc ttctactcct tgttgaacgt tagggactac tggatctgga
     3961 tgtgcagata ctggtgctgt tttgttcttt tcatcgttca caccatttga ttggtttggt
     4021 gtcgttgggt ctggatgtgc agacactggt ttttggttgt tcattttatt gttattattt
     4081 ttgttattgt tattcatgga tgtttcctcc taagatttaa aatagtgatc taagattttc
     4141 gtttgtttca gataaaaacc gatagcgacg ccgatcgctg ccatgatcaa gatcaataag
     4201 gtcttgaaaa agcccacggt gatccataaa acggctaata tcaatccaag taccccaaag
     4261 atgataggga gcttgtatgt cgaaaatagt tctttcattt ttggtccccc cctattctac
     4321 tcgtttgcgg tcattgcttc gtttagctgg ttcttcaaag cctgtgtatt tcaccgatac
     4381 tttcactggc tcttttgttc ccaatatgtg ttgtacttca ttttcgattt ctttcatcaa
     4441 tgttcctgtt ttaccaatga gtgctgaagt tcgtttcaac tcccctttta cattgacggc
     4501 gatcttgttt ttcgttgctt tgacatttac ttttggtgaa tggatgaatt catcttcatg
     4561 caagtgagaa cgaaccattc cttcaattgc ttttttatcc aacgtcaact ccccatcacc
     4621 atgtttcagt agaaagtttc cgattgtttt tggataaaac aggaaaacaa gtaacgtgat
     4681 aattgtcaaa atagcaaatg caacggcaag ccaaaataca tattgttgca cgtatgaatt
     4741 agtgatggaa aagaatcgaa acttctctag ctgaaaaggc aatggatagg ttgcacttaa
     4801 tagtatcgca aacaaaagca cagatagcaa aagtaatgtt ccgatcactc cgatcgtttt
     4861 tacaccttta ttcattttcg cacctcctca taggggtgaa acgatcaact tcttataagt
     4921 tgatcgcttc tccaccagtt actccgtaaa tttgggctgt aacataactt gctttattcg
     4981 atgctaagaa aacataaact ggtgctaatt ctcctggctg acctgcacgt tctagtaaac
     5041 tttgctgacc aaattcaggg atcgaatcag aaggttgtcc ttcgtctagt tgtaatggtg
     5101 tccagattgg accaggtgct acaccattta cacggattcc tttaggtgca agctgttttg
     5161 ctaaaccgat cgtaaagtta gcgattgaag cttttgttgc tgcgtaatct aataaatgtt
     5221 cgcttggatt gaatgcttga acagaagttg ttgttacgat tgctcctcct gctgggatat
     5281 gcggaacagc ttctttcact aaagcaaaca tagcgatgat gtttatcata aatgtgtctt
     5341 tgacttgctc aagtggtaac tcagcaatag actgacaaga aatttgctgt cctgcgttta
     5401 gtaccatcgt atctagcccg ccaagttcac tcacggcttt atctatgatt tctttaggtg
     5461 cttgttcgtc acgaagatca aaaggtagta agacaatctt acgtcctgca tctttcacgt
     5521 attttgctac ttcctctgca tctttttctt ctcctgggaa gaattgaaga gcgatatctg
     5581 ccccttctct agcaaatgca atcgctgctg cacgaccgat ccctgaatct ccaccagtga
     5641 ttagtacacg gcggttttct agttgattat tgccttcata ggattcttct ccacaatcag
     5701 gaacaggaat catattctgc tgtaaagctg gtgtatcctg atcttgttta ggaaatttct
     5761 ccgtatggta caagtttcgc gggtcgatta attttggttc tgtcattgct gtattcctcc
     5821 tagtttttaa attgtattgc caaaacaaat ttctttgttt gatacctgtt ttaaatagat
     5881 tctttaattt gtataatctt tccggtataa atggtaacct aaaactactg ctgctatcaa
     5941 agagccaaag actacgagta taaagcctag agcagaactt ttacccggta atcctcctgt
     6001 attcattccc caaatccctg cgaacaacgc cggaacggaa atgattaatg cagctgaatc
     6061 tagatatttc atgatatgat ttagattatt gtccatcatc ccgttgaata gatcaccaat
     6121 actctctaat aaatctcgat agatctcgat cattttttct gtttgtcgct gtctcaaatg
     6181 gacatcatag agtagctgtt catcgtctaa acgtttgatg aaagtttcag aattccataa
     6241 ttgatccatt gtttcccgtt gatctcttaa ggtatgatcg atatatacga tgtctctttc
     6301 aagatctgcc tgtttataca gttcttcatt ttccgttgtt ttacgagctg ctttatccaa
     6361 agcgtcaatt cgctttttca tctctcttag ttctttcacg taatgggtgt aaatatctaa
     6421 taatgtatac gtgatgatct tttcaaacga gtttaaatga tttccatgct ttgtcagcag
     6481 ccgatccaca aattcggttt ttctatcgat acaagtaatc aagagattat cggaaagtac
     6541 aaaagatatt ggcgttaatt ttttttcgat acgattatct gactgatcta gattaatcac
     6601 taccaaagaa aatggatgct ctagtttcgt ctcataaagg cgctccatcc gagaaacttc
     6661 ttccggatat tcggttccta cgaaaatatc atcaggaagc tcgaattctt cgattgcttg
     6721 ctcaatctct tcgggctttg cactatcaag tacgagccaa ttatattttt tttcatctgt
     6781 ttctattaca ttcttttctt catccacaaa gtagtatctc aatgtatacc tcctttttgg
     6841 actttctcga aactattagc tgaagaagca gttctttaat ttgatattat aatcgagtac
     6901 tgcgatttca ttttctaatg aaaagctgtc aagctgtttg ttgaagtcca tgttcaatcg
     6961 tttaccgaaa taattttgct ctaatttaga tgtatagatg tccaataatg gatgctcgat
     7021 tttagtcgca tattctccaa attccgaaac aaaaggaatg atttgaaaaa agctgccttt
     7081 tgcaaaagca cctttgtccc ttagaaatgg atcggaatca ttgataagcg cgagtgcgat
     7141 ttttgtattt tccccaacct tttcaattaa cgtctctact gcatttttag acattgtaat
     7201 ttccattcct actccccctc ttcagttgtg gtcttctatt atttaacaac tacatctgtt
     7261 tttggttgaa cttttgcata ttttggatat ttagggaatt tagctacaca acggaaagcc
     7321 gtcatccctg catatttttc gtaatatttc ttcgttggcc cttcaaaatc cttgctccac
     7381 ggtttcacat gtcctgaaaa atggataatg taaggattgt tgcgagtttc ttcgtattca
     7441 cgttcacctg ctgctgttgg atgttttttt gcttttgcca tgatatagcc ttgtgcattc
     7501 caacgcggat gaagtggtaa ccaacggtca tgtaagatag catttaatgc atcttggtca
     7561 tggaatcgta atttttctgg attatgttcg atgaaatcta atactttttg cgtaatattt
     7621 tcatctaacc attttttcac attgatcagc atcaaacctg agttgaaata acgcattgat
     7681 ttagctgaaa ttttcatttt ttccagtcgt tgatggaacc cagcgtcttc aacagctgct
     7741 acgattgaat caccgaagtc aagacgccat aatttagaga tatcttgtaa agcgatcatg
     7801 tcgcaatcca tatataagat acgttcaact tctgtgccgc ggaacaattc cggaatcgca
     7861 atacgataat aagctgtttc tggaatacga tcgctgatta ccacatttgt aaagaattct
     7921 ttattgattt tcaagaattc cacatctgag ttcattcgtg cgtttttcac tgagaagcgt
     7981 aaaagctgtt tactttcaaa atcgatatca tcgtcaatca catagaaccg aacaaattta
     8041 gacgggttgc aattatctaa tactgagaca aataatgcag ctaaatgtgg tacgaatttt
     8101 gtgttacaac ttgcgactac tgctatttct tttttattca ttgatctcgc ctactttcgt
     8161 tagagtactg tgtgctaatt tttttaagta taaattggta tacggatgat ctttcaacgt
     8221 attccaaggt ttatcatgtc ctgtaaagtg aacgatcgaa ggtttttcat ttccttcttt
     8281 atactgacgt tcatattttt catttggtgc tggatgacgt tcaaaaatca gcgaagtctg
     8341 catgttccat tttggatgaa gttgttccca atcttcataa agtacagcat tcaaagcatc
     8401 ttggtcgtga tagatgattc gatcgccatt ttcactgagg taatggatag ttttttctgt
     8461 aatttctttt ttattccatt gatcaatgtc aatcaccatc actcctgaat tgaagtacaa
     8521 gtcatcggaa tcgattccta atctttccaa agctttcact tggcctggat cgataatagc
     8581 gccgattgtt tttccattta acggctcatc atatagtttt acgatatcgt ctagtactaa
     8641 cacatctgaa tctaagtaaa ggactttctt ataatcctct ttagctaata agtttggtaa
     8701 agaaattctt aagtaagcgg tagttgtgat atggtcactg actaggaagt cttcgtagat
     8761 atctttttcc actgtcagga attggatact tgcattactt gaatatttat ttaccgtttc
     8821 ttccaatcct tctttactat attctgatag accatcgtca atcacataaa attttatgcg
     8881 tcttgtttta ttgcaatttt ctaatgcagt tgcgatcatc acgctcaagt aaggagcata
     8941 attttcgtct gaagcagtta ccacaggaac tacgccgtat ctcttctcca tcaaaatcac
     9001 tcctttttct aatctttttc taacctgttc tacatctaga atattcctca tttggtttta
     9061 aagcaaaata tatgctttgt tttcattgaa tattttaaaa tttttttatc acaaaacgca
     9121 tcggtaagcg ctaactattc gtttttcatg gctttttatt caaaggtatt gaccaaaaac
     9181 tactatatat agccaccttt ttcttaagaa tgttttttga aaaaattcat aatgacaaag
     9241 caagttagtt tcattttttt aaattctcat ttaatcttaa ggtaacagga aaatagatat
     9301 gtaaaaagaa agtaggaaga taaaatgaaa ctagcagcga ttgatttaga cggtaccttg
     9361 cttgatcgaa atggaaagat accagaagaa aatatccaag cacttcggaa atttgatgaa
     9421 aatggcggaa tcgtaaccgt cgctaccgga aggaacagca tttctgctaa agatattttt
     9481 tccgaattag gaatcggtgg ctatttgatt tcttccaatg gttcactgat tgctgaaatg
     9541 aaggatggaa aaatggcgaa agttctcaga cgttcaaaaa tagatagcga tacactgaga
     9601 aaagccttct tctatgctca agaagcgaaa atatccatca ttgctagccg agaaacccaa
     9661 gatgatcagc tgacattcga tgaatcaaat ctagtcaaag atgaccctta ttatgaacat
     9721 ttcaatttac agaaccattc ttttgatcaa attttaaata tgttggaaga tccttctctt
     9781 agctatctta aattagcatt aacagataag agtgaagaaa aactacagaa gctacaaaga
     9841 gatctgcaag cagatggtat ccaatcagta ttctctgatc cgcatttctt agaaatcacg
     9901 cctacaggta tcactaaagc tcattcactt gtttttctgg cggattacct tggaatcgaa
     9961 tcgagtgaca tcatggcttt tggcgatcaa gaaaacgaca ttgctatgtt gaattacagc
    10021 gggttgagta ttgcgatggg gaatgcacag cgacaagtaa aagaaattgc aaaccaagta
    10081 acactgacga atgaagaagc tggtgttgct tatattttaa aaaacttcta ttaaaaagaa
    10141 taaaatgacg atatgaatgt aggaggaaag aaaatgttag ttattattga tatgcaaaat
    10201 catattcttg atccaaacag cgaattttat attccagagt cagatcaatt ggcagaacgt
    10261 attgctcaaa gattagctaa agcacgccaa aataatgaat atattctctt cacacgggat
    10321 ataccagttg aactgaagga caaagaagaa gaacgagaag atttgcaatt gatccctctt
    10381 ctttctccac aagaaaatga acgagtgatt aaaaagtatt actttacgat tccacctgaa
    10441 actttagctg aaatccagga aactttattt gaaagcaaag aagaacaaaa agagatcgaa
    10501 gtagtcggga ttgaaacaaa cttgtgtgta ctctctaatc tgataggcct gcagagtgct
    10561 tttcctgaag cagacttttt tgttgatcca atgttagtct ccagtagaaa acacggagaa
    10621 tccgctttag agctgttgaa agatttcaac gtctctatcg tcgaatcata aaaatatcta
    10681 tcttcattta cgatatttaa cacacaataa aaaaagcacg cagaactgtt ttagtcctac
    10741 gtgctttttc tatcaaagta gattggcttt tttatgacac agagtgaaac ggcaggctca
    10801 cgacctcttt cttaaatggt gttcaatcag ctgaccctcg gtattagctt aacaaacggc
    10861 aaaatatgag gaactatttt tccgtttgtt aagctaatac tcaggtcaaa acgctgattt
    10921 cacaacctct tccttaaacg gtattcaaaa gcttgcatct gcagtaataa gaacagccaa
    10981 gtaaaaacat aagaagctgt ttttacttgg ctgttcttat tacttgatgc agggcagctt
    11041 tttcacaacc tcttatgtac cttgtaggac tcgaacctac gaccggacgg ttatgagccg
    11101 tctgctctaa ccaactgagc taaaggtaca tcataaataa aatttatttt tgttactttt
    11161 caactatagc acgaatgaca aactctcaca agtttcaaaa tataagtaaa ataatattgt
    11221 tattcttatt tcttttactt gtgtcataac tattttgtta ctttaatttt tatttgctta
    11281 ttttagaaaa aatgttattc ttttatttat tctcaatgtt aggagtgatt attttgccat
    11341 ttattgcgat tttattcgat ttagttgcgg cagcagctta ttttctccaa ttaaattatc
    11401 aaacctcagg aattctgttt attggaatga tttttcaagg tgtgattacc cttttgcttc
    11461 ttgtcatgat gctcagctat aaaggaaaaa gatatgcccg tattcaaaca aaagtatttg
    11521 ttaaatatgt ttccattcgc tatgggatca tcattctttc ctttttagtg aatgcgatcg
    11581 tcctcttttt atatgtattg aattacttag atatcaatcc attgattttt tctcgataga
    11641 taagacacat tcagcggaac agttcctgct tatcagcaga aaactgttct gctttttcat
    11701 ttttcattga tctattcttc ttttattttc ctagcatttc atttgtgatg tatgcaataa
    11761 catgttatct tttattatat gaatcgttga ggagtccgtt acatgattac gttggtgaga
    11821 gttttgtttt gggtgcctgc ggtcgcactg gtcgcaagta ttgtttatct tatgaattgg
    11881 aacaaagaac ggttttattt agctattttg actcttccgg ctatctactt tatgtggaaa
    11941 gtttttaatt acaactactt tgaacccgat agtgttttta tagaagaatt atcaggactg
    12001 gttttgtctt tattgatcgt cattctttat ttgatacgtt taaataaaaa acattgagta
    12061 ctattgattg catgtgtagc tttctatagt cattataact attctactat aatgaaaggt
    12121 gattaaatga gtatcgaaga agctatttta ctggatactt tacgttgtcg tctgaatttc
    12181 ttaagaactg gccgatcttt atctcaagta gctgtttcta gcgcgttaag tattccttta
    12241 ttcaaatatc gtaagtacga agaaggagaa gaaattccaa gcatcattga attaatctat
    12301 atcgctgact tttacgatat ttccgttgat tacctaattg gtcgctcaga aacagcaagc
    12361 aaactgaagt gattttttcc agccttggtg ctggtttttt catttaacgt ctaaggttaa
    12421 caatctatat ataaaggaga catttctatg cgattatggc atgaaaaatt gatttcaaag
    12481 cttcctcgtc aacagctttt aggacaacat cgggaatgct gtgcattaag aggaaatggc
    12541 tggggaaaga aacatgctac tgtggattat gtttttcact attctcctta tagattattc
    12601 caatatcatc agcttgtcat ggatgaaatg gaaaaacgtg gttacagccc agcaccagag
    12661 tggaaaaatc ctatgtatcg tggcaaatca tgcgaagcat tttttgattt acctactgta
    12721 gagcgcaacg tgccgattta tccggaacac gatgaagttt atctagcaga atgtttagca
    12781 aatttggagc aaaaaggaat ttatcttacc taatataact agaaaagcct tctatctcct
    12841 cttacttcat taaaaagctt taaccatctt agatcaagct aaaatgtcgt aagttttagg
    12901 gttatcttca tcctcacgtg caaaactaaa agcgtactct agttttggtt catcgccaac
    12961 ttccctagac ataaatgaac atctcctgac gtggtttaaa agtaccgcat cttcgacgtc
    13021 tgtatacgat gcacagcaca gattgcttct tttgatcttt cttttgattt ttctgttgct
    13081 tcttctacac cttcttcgat tactacatcg atgcttacaa ttgcttctgc ctaatattcc
    13141 catgcatcgt cgatttaagc ctctgtagtc actgtgatcg tttccacatt ttaactcctc
    13201 tgtcgtggct tcagttgatt ttgtgatcag ttcagttgct aagccagagt cagaacaacc
    13261 tgccattgct agcgttaata ttgatagtaa aaatagtttt tttatcataa ggttcccccc
    13321 ctgaaaatag actaaaataa taacgctttc tttttttgtt ttcagacgaa aattaataat
    13381 ttctaaatat tctttaaaaa agcttataac tattatgcct tttttaatat ataacacagt
    13441 tatttttaaa aataagaatg ctaaatcact ctacaataac ggcgaaagca caaaaaataa
    13501 aaaaattatt acgttattaa aaaaacagat gaaagatcag gttttattag atctcattct
    13561 ttcatcactt gaagggattt aatgaactac tttttcctct ttgtcgtttt tatatattcg
    13621 tattccttca aacagtagga tagcctcttt caatgcttga tatttgaact gtccgttact
    13681 taaaaattta gatgtgccgc cctcttccta gaacatattc ttttttactt tttcattaat
    13741 tgacagacca atcgaacgaa actgtaaatt tcgataggat aatgattggt caaactcatt
    13801 cattttcaag acatctcgat tcatattcaa gataggaatc tttttatcaa catcacttta
    13861 ttcgtatttt cctctaccat aaaagcttca cgctccacaa aattgtttta tacactacta
    13921 ttcagcccat tcaacgacca atgaattttt tcgtacaaaa aaaccgtctt ttctttcgaa
    13981 aagacggtta aaagtcaatt tttattaagc tttaacaatg tttgttgctt gagggccacg
    14041 ttgaccatct tcaacatcgt aagacactgc ttggccttct tctaaagttt tgaagccgtc
    14101 accttggata gctgaaaaat gtgcaaatac atcatttcca tcttcaccag tgataaagcc
    14161 aaaacctttg tctgcgttga accattttac tgtaccgtta ttcataaata aattcctcct
    14221 gatacgtatc aatgtacgtt ttttcgttgc aataaatatt tgataggcaa aaggagtttt
    14281 atctatgtag atatatcgct caaattacgt ttcaaaatag attactcatt taatatatca
    14341 tgctttttct aataacacaa ggataatgca atgaaatata aaattcattg tcttctattg
    14401 tcttcgaatc gaagaaaaag ttgaataacc gcgattgatt cactttttgt tttcttgttt
    14461 atttgctttt atctgcaact tttgacttta aaatttctta actatgaaaa cctttcaatt
    14521 ggtggtatac ttataaatgg aatttcgtta tcaacgcgtt cgttgccttt cagcaagtat
    14581 ttaaagaaag gagaatggct atgacattct ataacaaaga tatacaatat cgagtaacct
    14641 tggatacaga tttgaatcta tttgtcgttt ttgacaaaga aaataccaat catgtagcga
    14701 caggtgttac gatcgaacaa gcagtgcaag aattaaaaaa atctgcataa ggagtggaaa
    14761 ccctcatatg gacgattctc gttcttctct ttaaacgcat ctactggtag ataacagtag
    14821 atgcgttttg tgtttgttct aaattgttca ctacaaataa ggtagatact tcaaaataaa
    14881 aaattacttc tttttcatct gttccctcag tcgtgcagga caataaataa agaggactag
    14941 aaaatagtcc tctttattag agatacaacc ctttactttc taaaaatcgt tttgcttgat
    15001 gcaggtcata aaattcatag tctgctttat tggattcata taaacttaca tctactttca
    15061 acttatgctt cccattatga tcgggcaacc ctatcaaatg atctttgatg agaaaagaca
    15121 aaatgcccgc tcgccttgct gcttcgatcc ctgcaatcga gtcttcaaat acaagtgctt
    15181 cacttggagg aatattcatt tttgaacaag ctttcaaaaa gatctctggt tccggctttc
    15241 ctttttttac atcatcccct gaaatgattt gatcaaacaa ggcatataga ttttccattt
    15301 ttaaatacat ttctactttt acccgtgtat tagacgaagc cacgattgta tggattcctc
    15361 tttcttttgc aaaagataaa atttcttctg ctcctttttt cgtatatact ctcttatctt
    15421 ctttcacgat tttttcttta tattgattga ttgcttctcg ccatttgata tatggaacat
    15481 cttctccgta caaaatgccc atttgttctc ttatcgccat ttctgtttgg ccagttagta
    15541 aataatagac ttccttacgc atttcataat catacttttg tgctgatttt acataagcac
    15601 gataagctaa acgtccagtt tctaataaaa ggccatccat atcaaagatg aagagcttga
    15661 ttttattcat aatgctctcc cagtggtttt tccttactta tcgcctcata tagaccttgc
    15721 atgtaagtga gtcccattgc acgatcatac aggccatatc caggcatagc cacttcaccc
    15781 cacacggttc taccatgatc agggcgtata ggaccgtcga acccttcttg caccaacgct
    15841 ttcataatat gatacatatc aagggagcct tctgtagagg gatgtgccgt ttctttgaac
    15901 tttctttctc ctaaaaactc cacgtttctg aagtggacaa aatggatgcg cgaacctacc
    15961 tcatggatga tttcaactaa atcgttttcc ggatttgccc ctaaagatcc tgtgcacagc
    16021 gttagtccat tatatggaga atctactgca tttagaattt tcttcaagtc gccaagattt
    16081 ttcgtcactc taggaaaacc aaaaagttcc catggcggat catctggatg gatagccatt
    16141 tttacatctg ctttttcgca cactggaatc actttttcta aaaaataagt cagattttca
    16201 aataattctt cttcggtcat tccttcatac agtttttcca gctgagcgaa ttttttcaac
    16261 cgttcttctt cccaacccgg caatttgaat ccctttgact ggctgtgtat caattgatac
    16321 atttctcctg gctccatctg atcgacgatt ttctgatcgt ataaaagaga atagcttcca
    16381 tcgttgtttt cattaaacaa atcagttttc gcccatccaa aaattggttt gaagctataa
    16441 caaatcaatc gaaccccaca tcgagacaag tttttgattg ttcgtatata gttatcaata
    16501 tagtaatctc gttcatctgt ccctgccttg attgcatcgt ggatcgctac actttcaatt
    16561 ccaagcagtt ccagtccttg gctctcaaca gatgctttca actcctcaat ttctgaaatc
    16621 tcccaaacat ctccaggcat tttagtcagc aaagttccaa ttatcccatt tattcccggt
    16681 atttggcgaa catattttaa tgggatcgaa tccccttttt caccatacca tctaaatccc
    16741 cacttcatct tttcagcctt ccttctaaaa atcgtcctca tctaattttt tttcttccgc
    16801 tgaagcatgc caaacagtta aattatcttt tccttgtttg acaatttgtt ccaccgcttc
    16861 ttctatcggt gtgtgaagca tctgatgatt gattgcttct aacaacattg gcagattcac
    16921 gccccctatg acataagtgg ctgctttctt ttcttcagtc agttcattga ctgccaagag
    16981 cgcttgattg tacggacttg cgctaattag atcaacaaat actagcatgg gttctgctgt
    17041 gttgatcata gttaattttt ctttgacctt ctctccgaat gtttggatgt cctccccaga
    17101 ctctaagcac attgtttcaa tatggctcga tgtcccgaca attacttccg ccgcatcttt
    17161 cagtccttcg ctcaacttac catgtgtaac gatcatgatt tccaacatta gtcttctcac
    17221 tccttgtttt gcacttttta cttatcgaaa aagagcaata atctgattgg cattttgcca
    17281 attaaatgtt ttccctcgta aatctgtttt ggtcaaatag aagaactgcg cttgcttttt
    17341 tcttgcacta aaaatataat tgacgttttt ttctttcaac ttatcaactt gtttcagcca
    17401 ctgttcttta tttgaaaaat aatttcccga aaactgtagc ggtgtatctg ccccaacaga
    17461 gtctagataa aaaagaatag cctctttttt catacccgat ctcacgctgt ctaagccctt
    17521 ttctccataa cagccttcat caacaaacgc atacgctaca ctcggatcat caatcgtacg
    17581 gatcatttct agcatcgtta atatggatga agtatttcga ataaaagttt gtctgctagg
    17641 ccatccgcga gctgcttttc ccaataagaa aaagtagctc ccaaatgcta gtacagtgat
    17701 acctgtttat acggatagca gatcgaatac gtgatgagga tttttgttat atatcatcat
    17761 tccccaccaa cctaaactga acaacaaaat gaaggacaat aatatagagt agattgtttt
    17821 tttcctttgg tctttccaat caaacatgaa ataacttcct aatgcatgaa cgggtgtatc
    17881 gtaataagta cagataactt tctctgcttt ttcgatatct ccaacataaa tattttttga
    17941 tcggtaggct agcgtatcgt aagcaatgac tgtcacatct gttctcatac tgtaaatatc
    18001 tgatactaat gctgaaagaa aacgctgttt actctttttt gtacggcgct tacggtaaat
    18061 atagcgataa cgaaattccc aatcacgaaa cagctcgttc ttcttcattt tttcgccctc
    18121 tttatctttt ttctaagcat ttgtttatga caaatcaaac ttgttcaata catcttttaa
    18181 tcctgtttta ggtgcagatg gagtggcttg aaaataaata ttctttacgc catattgttc
    18241 attcatttct ttcaattttt cagcatctga tttatttaaa taaacagatt tcgtcactaa
    18301 aagatctgta tcaggatttt tttgagcaat ccctccaata ttcaattctt ccatggggat
    18361 tccgtgtttt actaagtcgt aaatcgtttg gactgttttt gcgatcaaaa tacaattgta
    18421 ttctttaaat tgatattcat cccaatagaa tttagctttc tctggtgtaa tgacaattgt
    18481 tttttgtcct gtacggcttc ctgcattttt gtaaagatct ctcataaatt tatcttttgc
    18541 tacaacttcg tctacaacaa aaatggaatt cactccactt ttttgagata acgttaccat
    18601 tacttgccca tggatcaaac gctcatccac acgcgctaaa ttgactacac ccatcttatt
    18661 cacgttccct tctttttata aaataccgat tcctgctagc acaattaata ttccagtcag
    18721 ccataataat gcttgtgtga ctttcaatcc ttttttcgta tagaacaagt acacacccat
    18781 tacgacagct aaaggtaata tccctggcac gatttgatca agaatttcct ggataacaaa
    18841 ctcacgtccg gatatcgcaa atttcaatga agattctact tttacatagt ttcccgcaag
    18901 cacccccatc ataaacaacc ctaaaactga tagcatttca atcgctgtct gaacaccagt
    18961 gttttgcatt aggcctgtag cattacggcc catagtgaaa gcttgtcttg cgaaaaatac
    19021 ccctagtaaa acctgataca acccaaagca gataaaagga aaaagtgcgc ctaaaggact
    19081 tccctgttgt gcccaaggta ccgcgattgc gataaaaata tattggacgg ttcctgaatc
    19141 gattgcatct ccgattcctg ctagtgcccc catcaatccc gctttcgtgt tatacatcaa
    19201 gtcatcctgc atcaagatct ctttttcttc atactcttct tctgctcttt gctgttccat
    19261 agaagacatt aggccagtaa tcacaccgcc accccagctt aattgagtgt tgaagaacag
    19321 taactgccgt ttatatgctg cttttaaaga gtcttcatct ttataaagtt ttttcaagat
    19381 tggcatcatt ccgtatagta gtgatggcgc caagtaacgt tcaaaagagt gaggaatttc
    19441 gtttgcaaaa tgccatctca gataggcttt tgttacatct tttttcgtga tttcttcagg
    19501 agcacctgtt tgattatcca ttatttcagc catttcccat tcctcctaaa ttaaaatccg
    19561 tcatcatagt catcttcgtc atcaaaagat gctgaattgt tattgcttgt ggcaggctgt
    19621 acttgtttcc ctttttgcga ctggacaaag atcaaagcga taataatccc aaaaatggca
    19681 taagtaacca tcgtaatatc taaagatttc aaaacaacac tcataaaata agcaaggaag
    19741 aaaaagacca gataatcttt tcgaccgata acgtatacag ttgtcgcgat accgattgcc
    19801 gctaaccctc cacctactac ttcaagaatg tggataacga ctgttccctc taaagctttg
    19861 attacatcag cgatcaatgg cgcccctaaa tataaagcaa tgaaaacaag cggaacgaat
    19921 aataaaaatg aggcaaccgt tggataaaga ataattgatc gggccatagc ttttgtattc
    19981 aaatcttcta cagctttgtc tgtatattta cctaaaaaag tattgatgaa aaaacgaaac
    20041 tgatacaagt aacttccgag caatccgact ggcaccgcaa cggcaatcgc tgcttctggc
    20101 gacagatccc ctaataatgc gactggtact gcgatagctg ctgcaataga tggttcagct
    20161 ggcattgatc ctcctggaga aaaaaccccc atataaatca tttgcaaagc ggctgtaaca
    20221 atcatcgctt gtgcaacttc ccccacgatc aacccgacga ctaatccagt catcaaagga
    20281 gaaaaacgta aggtcaacgt ggctcctcca cctaaccagc gggacataac cgcggctacc
    20341 cataaagcaa tcaacaaact ttgtactaca cttaatgttt ccatgtgtcc tcctccttca
    20401 gatctttctg atataacctt ccagttccat cattgactgt atcagtgatt tctgtgttac
    20461 ctctatagga atcaaatgca ctttctcttt cgaatcaata aattcagcca ttttatctat
    20521 tatctgttta tctttcggaa ataatcccat ttgttctaga gaaaccggca gttctaattc
    20581 ccgatacaaa ggatataact cgtctatttt ttcccagcga ccttctagtg ccagttgata
    20641 gaaaatccca tacgctactt tttctccatg tagaaaacga tggctttccg gaatatattt
    20701 actgatagcg tcatgcatag catgtgctgc cgcatttctt gcgtatttat ctcctaatcc
    20761 tccaactaaa ccagcaacag caaagataat ctctgaaagc tgtttgaact ccgatgtcag
    20821 ttttctttgt gccatatctt ggattgcttt agcagaatga ttcaaaatct cttctttgca
    20881 gatcttcgca gtatcttgtg ctagcttcaa aaatgattca tcttgcaaaa aatcttgttc
    20941 taagatgagc tcagattcat accattttgc tagtgtatct gctaacccgg caatgaaata
    21001 tggaacaggg gaatcaatca ctaattgggg atctgttata aaaaaagcag cttgtctgta
    21061 aaagtgttct gttttccctt ctgcttgtcc attctcctta tacatgacag caagaggtgt
    21121 ccatggagca caattactag ctaaagtagg gatgactccg aaatcgattc ttgcaagatt
    21181 ggcactataa cccactagat cggtcagttt tcctccgcca acgccaacta cgaaatcgat
    21241 ttcatttttt tgatgattgt agctattcgt ctggcttcag cataactaca ttctccagaa
    21301 taacgatgat aaaaaaattg aatcgtttcg tcattcaaaa atactaattt aggtagcgcc
    21361 ttttcccatg ataccgttcc gtgggtgacc agtactcttt tcgcgccgta tgatttcaag
    21421 agatcagaaa cttttgaaat accaccttct tcatataaat aaaattgagg gcctgttttc
    21481 acttttaaac cgttcaccat tttcttcatc atccttttat atagttgctc tttgtctgga
    21541 cagaacgttc aggaagaagg tgctgactga tctgttcgac atctctgaca catttttcac
    21601 ccattgcttc taaacattcc cttgtgtagg ccgatatatg tggcgtaatc actacttgtt
    21661 caaacgctaa atacggatga tcttgacgtc ccggttcttc ttctaaaaca tctgtggcat
    21721 atcctgcgat ctttccgctt ttcagaccat taatcatcgc ttcttcatca actagagcgc
    21781 ctcttgcact attagataga taaacatttt ctttcatctg atcgacttct ttatcagaaa
    21841 tcatgtgata gttctcttct gtcaaattcg cacataaaca aatgatatct gattgttcca
    21901 gtaattcttg aagttctact ttttttgcac caaagctttc gatgtataaa tctgatttgt
    21961 aaggatcata agctagaaca tcacagcgaa aaccgttacg caaaatttcg attactccgc
    22021 ttccggtatt tcctgcacca atcacaccaa ctgttttgtt aaacagcgtc ctaccgacga
    22081 actccgcccg atcttcccat cgatcgtcct tgactcttgc ttgtgcttgt gtcgtgcgtc
    22141 gaagcatgga caacaaatta gttatattat tttctgctac agcatttcgt tcaattaaag
    22201 caggtatgat agatacgatt gtctggtgtt cttttgctgc ttttaaatca atattgttgt
    22261 aaccaatacc atgtcgggaa atcaatagca gttcatcttt gttttcaaaa aaatctcgtc
    22321 gaaaaaatgg cgtaacactt gcaataatga tattgaatcc tttaagtaac tccgctagtt
    22381 cttttcctgg aatctcttga tcaacagtaa agaaatgaac gtctccaact gactttaatc
    22441 tttccaagtg gtgtggaaag actcttccga aactgctgga attaacgatt gctatatgat
    22501 aatctggcat tttactcacc cttttcaact atttcatgtc cgccaaaccc atttcttagt
    22561 gctgaaacta cttttgctga aaaactatct tcttcctgtg aaagattcct catgaacaaa
    22621 ctagttgcaa ttactggaac tggaacagcc atttctagcg ctgtttcaac cgtccatttt
    22681 gcttcacctg atgcagaaac gattccccga taattactta aattgggatg ttcgtttaac
    22741 tgatcttcca tgatttccat cagccagccg cgaatcaccg aaccatgatt ccaaacacgt
    22801 gcgacttgtt ccaagtcaaa agcatactca cttttttgta caagttggaa tccttcaccg
    22861 attgcttgca tcattccata ttcgattcca ttatggatca ttttcaagaa gtgtccgctt
    22921 ccggatgcac cagcatacag atatcctctt tcaattgcta catctttgaa taattgttcc
    22981 acggatagaa aagtttcttt atctcctcca atcattaagc aggcttgatg tcgtgctcct
    23041 tcgattcctc cagaagtccc acaatccaag taaccgattt catttttctg aaactcttct
    23101 gctcgacgga ttgaatcttt ataataagag tttccgcctt caataataat gtctcctggt
    23161 ccgagttttg gaaaaagttt tcttaacatg ttttcggtta tctctccagc aggaagcatt
    23221 aaccagatga tttttttctg ctcaaaagta gctagaaatt cagagatctc ttgataagca
    23281 ggaatgtcat tttctcttgc ctgactaaca gctgtacttg aaatgtcgag tccttgtact
    23341 ttgtgatggt gctcttttaa gtttaaagct aaattcaatc ccatttttcc caaaccaatt
    23401 acaccaattt ccatgatagc gcctccattt cttataccct cattatacaa aaaaattttt
    23461 ttgtaaatag attttacaaa aatatttttt gtttgatttt ttcctactct ccttgtatct
    23521 ttaacattaa tgagaacgga aaaaatgata atcttattat gaaaatgagg aattctcatg
    23581 agcgtctcca taagactaca aatcaaaaca atgtacaacg acttcagccc aaaagaacag
    23641 gctatcgccg attatatttt agaaaatcca agcaaagtaa gtcatagtcc tattagcaat
    23701 ttagcaagtg aactgggcat tgctgactct actttttttc aatttacaaa aaaacttggt
    23761 tataatggat ttaaagattt taaaatggcc atgttgatcc aagaaaatga tctatctgct
    23821 atttctatcc acgaaaatat tcagaaaaca gatactgagc tcactatggc gcaaaaggtg
    23881 ttcgagtcta gtatttcaac tttaaatgac acaaaaaagt tgttacaaca aaaggatcta
    23941 aaaaaagcgg ctactattat caatgaatct aaacgtgtct attttttcgg tgttggcggt
    24001 tcagagattg tagcaactga cgcttatcat aaatttttgc gttcccctat cgcaacttct
    24061 cacagcacgg attaccatat tcaattgatg gaagcttctt tattgacgga aaaagactgt
    24121 gctgttttga tttctcacac agggcaatca aaagaaacaa tccatattgc tgaaaccgta
    24181 agaaaaactg gagcaaaaac aatcgttatt actagccaag ctaattcttc ccttgctaaa
    24241 cttggcgatg tcgtttttat ttctatttct gaagaaacag aattccgatc tgaagcttta
    24301 gcttcccgta tttctcaact aagcattttg gactctctat atgtgatttt gatgttttac
    24361 aacgaaaaag aatcacgtcg ttctatcgct aaagttcgac atactatttc tgaaatcaaa
    24421 gaatagcacc ataacagaaa aagcgaaaaa tccataaaac aaaaaaagcc actaccaaat
    24481 atttggtagt ggcttttttg gttctgcaag ggtggtacag aacatcaata gtcggtgggt
    24541 tagaacgtat gtcatcgcat ctttggagaa ggttgtattg gtattattcg agttacttgt
    24601 tagatgcgat aacaaagtta gtatacagta gtaaaaaatt tatcttttct tttttttatt
    24661 atttttgttt cttattttct aaaaaattaa aaaaaatttt ggtgaattaa gtatttcctt
    24721 gataacactg gcttttggcc tcattttagg ttatcatttg taattttatt tcacagttga
    24781 tatgattgtt atgtaaaata aaaaagttta ggatacatcg aatttttggg gaaattcttt
    24841 tgggggtatc ctaaatcttt tctattatat tcccatattt tctattattg gtctagacgt
    24901 atgatggtaa actttgtacc tatctgattg ctgaatcatt aattgcttat cattagccat
    24961 ctttgtttca agttcgctag atgatcattt tattcacatc ctaacaaact tgtcacattt
    25021 atagattctt aatctattta tcatacaatt ataaaaaagg aggtgctgct tatgaaagct
    25081 atccatattt ctttgctttt tttcgctagt gcattgattt tatttgctat tcatctttgt
    25141 tcccagcctt atatcaataa caacggaata ttagtggaac cagcattctt ttgcttacca
    25201 ctcggctttt tgtcccttct tgcctccgca ggcttcggat ttgttgcttt ttttaaacga
    25261 tcaaaacaac aaatctgact tataaaattt acgtaaaaga gatcgtgaca ataatcgtgt
    25321 gatattccca aatttcgaat aaaaggtgcc ccttgccatc tctaactcct cagtcacaag
    25381 ttacaatatt cataaaccat gaaaagcttg tttattgaaa ttgctccttg tgacttggag
    25441 ctaagtgaca gattacaacc tcttttgcat cataagactt tactccttga aaaacattac
    25501 taacttttga tatgtttctt gcgcttgttt attgctgaaa tcaaactgat attcatggtt
    25561 caaaacagca tttttctccg cataatctac ttttgtgact ttcacccccg ctttctcaaa
    25621 tacagaagtt acttcttcca tttgtttcgt aaacgtattt gtatttccat ccgttaagaa
    25681 tgtgttttgc gtccaacgat ccgcatgtct gaccaaggct aaacttttga ccttctctga
    25741 ttgttcaaag tccttattat caaagtaagc ccatccacat ttttcataaa gaaagctaga
    25801 gattttatca cttacttgag taagtgcaga aggatccaac agaccagaca aagaaataaa
    25861 cttcgtaatc tgcttgttct ccaaagtcgg atcaagatga tcagcttttt taatttcttc
    25921 attttgaagt gctaacaaat attctccact aatttgtgca cctgccgaat ttccaccaat
    25981 cgaaatattc gaccaatctg cttgatcttt tatctctttt ttagctgctt gaatggcttc
    26041 gttcaattgg ataactggtg taggatgttt tgcttccggt gatcgttcat aatctatatt
    26101 tacgatgatt tgctgcgtgt ctgaacatag atattccaaa taatcacgac aatcattttt
    26161 atcccctcct acatatgcgc ctccatgcat ccagaaaaga atcggtaatt ttttcttttc
    26221 cactttcggt gtgtagatat ccatattatt atttttgtac tttgaaggat aggatatttc
    26281 tttttttata tcgatttgtt cgattttttg ctggaaatca tctggtcggg catatacttg
    26341 ttctttttca cttgtgtcaa attgttttct aacaagcaag ctaatcggct ttggtgtgat
    26401 ttgattaatc aaaaatacag tgactaaaat aactacgatg ataactggta ctgcaatcac
    26461 tattcgcttg aaccatttca ttcatttacc ctctctttct tcgccaaatc catgtgataa
    26521 tcgtgctaac agataaaaat ccacctgaat aaatgagaag cgaatgtttc ttttctccag
    26581 ttttcggcaa cattcttttt tttgcatctg tctttttttg tactttcact gtcatctgaa
    26641 tcggttgcgt atcatcactt gattgatcct ctcgaggttc attctttccc ttattgtctg
    26701 cattctctgt cggatcttgc ttttttggtg gagctactgg gatttttttg taatagaaaa
    26761 taatagttgg tatcgtctca ttaaaaatcc cttcagtcgg tccttcaaca tttgctaatt
    26821 cgtatccttc gaatgtcttt tgctctgtca tataattttc tccataagct ccgtaaagct
    26881 ggatttcgtc ctggtctttg agtagacttt tattgttttc atccacatac tttacgttta
    26941 tctgatcatg gaacactact ttcaaaaagt ccgttacatg tttcgtgtag gcagcatggt
    27001 caacttcctg tgcctttcca tgccctgctc cttctactaa taaaagatct ttataccctc
    27061 ctgataactc atataatttt tgcgcgttag acacaggtac tacatcatct gctgttccat
    27121 ggataatcaa tttaggcaat gaatctgaca ttccaatcgt aggtagagca gcttttgtat
    27181 ccaaatgcat ctcctgatca aaatagtatt gtttcaaaag gcccataaat aaatcttcat
    27241 gctcttgatc cccaatgatg tctaactgat tttttatggc atccggtagt gcgggggcta
    27301 ctgtctggct gtacgtaaaa cgtagttgtt catcaattga tgcaaatccg caattttcaa
    27361 taattccttt gacattgaca ggaatatctt tcgctaatac agacatcatc gtagctgctc
    27421 ccatcgaacc accataaagt aaaatctttt gagatggccg ctctcgaact tcttgattta
    27481 tccagtaaag gacgtcatct gactcatatt gtccataggt cacataatcg cctccgctat
    27541 taccagtcgc tctggaatca acaaataata aattataccc ggccttataa aaatcattgt
    27601 attcttctgt aacgatcccg ttattccaat tccctcgaaa tccgccatgg atcatgactg
    27661 ttttatctga accttgatcg acataatatg catatacatc catcattttg ccatcttgtt
    27721 tgtttagtac agtttgatga agttgttttg tatttggata gaagcctgtg ttttctgtag
    27781 gcgttgtccc atcatctgta cctccaagca tcgacatcaa cacactgttt tttgcaaaag
    27841 cgatatcgta caatagataa gtagcaatca gatgtttgat aatctcttta tctacaccat
    27901 aatcattaac agcaagctca gtgactaata actctattaa ttttgacttg atgtcttctg
    27961 ttggtccatt aagtatttct gtcatctgtt taccgaagta attcaaatat tctttaccat
    28021 tgaaattttc acctttaccg atatcatcat tttctgtccc attctctttg tcacttactt
    28081 tagcagaaga ggattcgtcg tttgacattt ttgtagctgt tgcttcttct gtttgttggt
    28141 tatctgtggt agcggtcgtt tcttgatctg tgctagtaac agatgtctca accgttgttt
    28201 cagtatttgt ttctgtttgt gaagtactcg atttcgtttc atttccagca tcagtagttt
    28261 ctgtggtttc tacctcccga gattccgatt cggaagaaat gctctctcca tatactgtcc
    28321 attgcgggac gcttgtactt acagcaaata agatgaccaa cgctcccttt aatacttgtt
    28381 ttgttctcaa gctattcact cctttttatg tttctaggag aattatatgt aaacgcaaac
    28441 attttttata caaaaaataa atggtttatc ccataaaaat agaacaggat tattttctca
    28501 ttttacgtaa taaagcagaa tggataaacc agtatccatt ctgctttttt taaacgaaga
    28561 aacaacttat tgctccaaaa atgtcagaaa tcgtttatcc caaattttct cgtaaaaagc
    28621 gattgtttcc tttgctttca taaaaggatt atcataagtt gtcgttgctc ctctacacat
    28681 cataagctgg tatcctaatc catgagcaaa cttcacagtc gtatctatac aatactctgc
    28741 ttgtgcccca cataattcga tcgaatgaca gtccaattca gttaataaaa cactcaaatt
    28801 agtcttataa aatgaattcg catgggtttt tctcacaaaa taactgtgct caggaataga
    28861 taattccgac aatagctccc atggttttgt ttgtggcact aattgagcat cttcgtgttg
    28921 aacgaaaata actggtttcc caatcgtttc gtatgttttg attcttttat tcactaatgc
    28981 tgtcactgtt tctaattcgt gtatcggcga agaatcaaaa catacccctt tttgtaaatc
    29041 gatcactact attgcgtcgg ctgtgtttga catacttgtg ccttctttct tttttcttga
    29101 tttaatagta tttcttatct agctagttcc attatacgtg acaacatttt cttattttac
    29161 acctctaaat ggcacttttc gactatttct tcatgttatt atttcataaa tacttagcta
    29221 ttggaggaat gtatgatgat taaattgtat acaggttctg gctgctcgtc ttcaagacgc
    29281 gcaaaacgtt ggcttatcgt ccatgatata ccgtttatcg aacagaactt aattcgtcaa
    29341 ccactaacca aaaatgaatt tatccactta ctaaaattga caaacaacgg cgtgaccgaa
    29401 atgctctcta ctcattctat tagttataaa aatcttgttc acagaataga tgaactcagt
    29461 ttgagtgaac tatatattga gattcgtaca tccccttctt tattgaaaaa accgattatc
    29521 tacgaccaat ctgcaaaact tttgactgga tttagcgaag ataaaatcag gatgttcctt
    29581 tctaaaacta aaagaaagca agagctcaac gaactcttgc tttctggtca tcttgtcgat
    29641 tttaaagaaa ataatctttt tgcaatgtct taattttggc ataaacaatc tgcttttctt
    29701 aattaacgaa atccaatttt tccaatatgg atctattttt ctcattcctg atttttatga
    29761 tttcagcttt cagacgcgcc caatcatttt ttgtaggttg tccattccag taaaatatct
    29821 gtgtattcgt ttgatcatat gcctttttgt cgataggata atcgctaatg acaatatcag
    29881 gtaactgatc agcggatgca ctatatttta ttgggcgttc agtcatagat aatatccttt
    29941 tctttgccca taattcctgt gttttaccat actttgattg aatatagaat atgacaggtt
    30001 gttcgtgttt tataaaaata tccctgacta acatacagta ttgaaaaatc aaccgtctgt
    30061 tcttttcata ataagtatta agctctggaa ttctgcgagc taccccacta aaaaactgtt
    30121 gcatgattgg atacatcact ggaaatatat gctgaaaatc tctgtcttct gctgattttc
    30181 caaaagcatc caccttcttt tttgtcccaa aaacccttga atacaaatgg atcattgcca
    30241 aattgacata tagataattt ttttctgaag ttgtaaaaca aatcttgaag tttttttcaa
    30301 aattttctac aatagacgat tcaatccagc cccaactttc ttgtacttta tctggagtat
    30361 ccaacaaatc ttcttccaaa taggtgttca ttacaccaaa cataaaataa aggtaagctt
    30421 gctctgttgg agtgatgtga ttcatcgacc agaagtttgc ttcaaaaaaa ggctctagta
    30481 tgtaatgcgt aaactcttct tttgttatca atggatgcac aaatttgttc atctcttctg
    30541 ggacatacgt aatcgagtgg ccttgtttca ttcgttgcaa cgaaattctt agtaggctga
    30601 tccatttctt tctatctata ctacgcgtat atggcgcatg tttcgcaaat ttttctaata
    30661 gttgacgttt attttttata cttgataata tatcagaatg attttcgtcg aatgactgcc
    30721 aatacatcaa gtgaaaaaag tatcggatac ggtattcttc tccttctatc ggattacctt
    30781 ttttcaagct gcaagataaa tgatagtttt tcaaaatagt attaagttct cttaattttc
    30841 tttgaatcgt acgcaaactt atataatttt ttgactaaga ttttctaagg attgataagt
    30901 acctttgtaa agtgaatcca gtaaaatata accaatcgtt ccctctaaaa gtatagaata
    30961 aactttactc agtaaaaact gagaagaaaa ctcgactttt atcatcttgt tttctgaaag
    31021 aaaagataat ttatattctg gatacctttc gcaaaacgat tctgcttgtt gaatcaccga
    31081 attcatctta gccagggtgt agtttagatc taaagcgata tccttcacca catataattt
    31141 ctcgtctctt tcataacaat agttcaaaaa ttgatatact tgcctttcat tgatatcaat
    31201 aaattcttca aacaaagtac atactccttt ttatctatta tttagactta ttccgacagc
    31261 tacatgaata acgtacaaat agattcgtta ctgatttttc agagatacta ccatgcgcag
    31321 tgtgcattgt caattattct tgctcttatt ttccatttgt gttcctgtta tttcctgttt
    31381 ctcaaatatg ttagtaaaca aaaatagatc tggcaaagct acaacttcgc caggcaatac
    31441 agcactctcg aatgaaatat tcactcaaaa atctatcgtt ttattcaatt ttagatctgt
    31501 tgcttttatt ctttatttca ctcgatggaa gagagaacga aaatagcttg ctcctacaat
    31561 caaaatgagt aacacaccca tccatgtaat tagcttgttc aaggttctac taccagtttc
    31621 tggtaaatcg ctttttctat tatctgtttc tttcgctttt tcttgatgat caattccacg
    31681 agaaacaaaa tcaggctgtt ttagcacact ttttaggttg ctccctgcat ttctcttttg
    31741 ttccttagtt ggtatgatag gtaccaaatc aagttcatta tttacttttc ctgtgctgct
    31801 ttcgctgctc gtgcttcctg tgctactctc actactcatg cttcctgtgc tactttcact
    31861 actcgtactc tccgtactgc tttcgctgct cgtgcttcct gtgctacttt cactactcgt
    31921 actctccgta ctgctttcgc tgctcgtgtt ttctgtgcta atttcactgc tcgtactctc
    31981 tgtactgctt tcaccgctcg tgttttctgt actgctttca ctacttgtgc tatccgtact
    32041 gcttggcggt ccaacaactg tccaactgct tggtttcaaa ttctccgtga tcgtcatctg
    32101 tccatcataa aaaacaatca aatcaacttt atctttactc ttgatctcat caatcgatag
    32161 ttctgcagaa atcattattg tatactcaat accagcggtc cattgtacgt cttttaaata
    32221 aacttcccca ataacttttt ctgaacttcc attaccatcc caaccatatg ttagaacagc
    32281 atgtacatca ctagcattca cgcttttgtt tggtttgact ggaatagtaa tgacttgttg
    32341 tgtcatgtca taaacaatcc gatcagtttt cacagtaaat gaaagattct catttgcccg
    32401 ttcatttgca gaagtactga ttccaatcat tgctgcaatt atactcagcc caagaataac
    32461 aaataatacg gtcgctgttt tcttcatttc tatcactctc catataatta ccttctattt
    32521 gataaaggaa ttatataaaa tgaaaatgat gagaacacga cagtcagttg tgaaaatcta
    32581 acaaaagatg tcgtgtattc gcttgaattt gtttactttt tcgtttaatc aatgacagac
    32641 ttaaaaaagc aagaccgata tcagccttgc tttcttcatc ttttattgat aaacagcagt
    32701 gtatttcttc atccgctttg ttttatatgc atagagtaac aaaccaacaa tcaagactaa
    32761 caagaataat gtagttgata tagatgcttc agccccaaag tttcccccag taattattgt
    32821 attttgcgat tggatcagag tggagaaaaa accttgttct tgcgttccgc tgactggtat
    32881 acccaaaata gctccttgtg tccaattcca agtaatatga gcaccaatag ccgtaaataa
    32941 acttcctgta ctgtagataa gtgcgctgaa aaagcaacct gctaaaaaga tattgaaaac
    33001 tgccagaaat gtcatgttag gattcaatcc gtgcaaaaga gcaaataatg cagcagatcc
    33061 aatcattgct attaacggac caaatctaag catctgatgc tgaaaaaagc cacggaataa
    33121 aagctcttct gatgccccca ctgcaataaa taaaataaaa ctcgttatca gcggcacaat
    33181 gtttgcgttt cctgaatcta accgatacgc ccccgtcaaa tataatggac tagtaataag
    33241 cagaaacact ccaattccaa caacgagacc tcccgctaaa tacccccagt cttttcctcg
    33301 aacagaaaca ccataatctt ctattctttt tccttcgacc ttactagcaa gaaataaagc
    33361 tagtaaaaaa acagctaaat gtccgaccgt accggcaatt gctccaatcc attcactatt
    33421 tccaataaac atatccgcaa gtgcattatt gacaagaatt cctaaaacaa aaccaacaaa
    33481 gactattaaa acagatccaa tcaaccgaat aatcctgatc atctttcatc cctcctttat
    33541 attaagttta acaacccttt tctttcttgt ctcgtgaaaa ctatgtaaat gttctccatc
    33601 atagagagaa tagattttta cgaactaaga atatctacag caaccttacg aaaatgaaag
    33661 actgtctccc taattcttct gttagactgt ttttaataag gaaaggatgg gaaatttttt
    33721 gaaaaaacaa ctactaatta tgtgcctttc agcatgtgca attttactat tctcaggttg
    33781 tagcaagtcc aatgaaacga ttgcaacgtt taaaggtgga acacttacag ttcaggattt
    33841 ttatgataac ccaaaagtta aatcaaataa tcaaacacta ttaaaaaaaa tgattgtctt
    33901 caaagcattt gatgatgtat acggaaaaga gatttcttca aaggaagtaa caaaagaata
    33961 taatgaacaa atcaaaaaac tcggtccaaa ctacaaggaa caattaaaag cagttggcca
    34021 aacagaagag acatataaga aactctttaa acagatgctg gctttccaat acggtttgaa
    34081 agccaatgta aaattaacag ataaagatct agacactgct tggaaagaat tctatccaga
    34141 agttagtaca cagatcattc tattttcgac taaagaagaa gcagataaag caaaaaaaga
    34201 agcaaatgaa ggagaaaatt tctccaagct tgttcaagct tatggaaaaa ataaaacatt
    34261 aaaggaaact gatggaaaaa tgaattttga ttcaaccaat ccagagattc ctactgaagt
    34321 aaaaaaagca gcatttaaac taaaaaacgg ggaagtttct gatatcattc ctgtaacaga
    34381 tccaacgact tatcagcaaa gctattatct agtaaaaatg gtaaaaaaac aggataaagg
    34441 ttctaataaa gacaaataca aatctgagct agaaaaaatt gctaccgaag caaaaactct
    34501 tgatacggaa ttcatggata aaacaatccg taaagtgatg aaaaaagaca atgtaactat
    34561 taaagatcct tatgtaaaaa atatattcaa ataaacaaat ttgacccaat tggggatgtg
    34621 gcaaaatttg agaagtgatt tttggaaatt ccttcttatt tttgaggcaa accacttttg
    34681 ccacaacttc atcggggcct ttttttattt gtaccaaaac aaatcactgg atttgttaca
    34741 atcatgagga tataatttaa aaaagttttt tatttctatc acatgaatca atgcgccatt
    34801 aagtagattc tttcatgctt ccctattttt tcacttgccg tatcgcttca aaaacaacta
    34861 tcataaactc aaactcgact gaaaagttat tttaaaaaag actaaaaata tcccttctgg
    34921 acttgttctt cttattctgt tatactagag aaacacgaaa gatattttta tgcgacactt
    34981 ttcatttgtt tttatgaaat ttattcaaaa ctggcgtaac ttcagagtta caaggatgta
    35041 ttagaggtta gggaatacat cgtttaaatg agaaataagt aatagttagt aatagtcacc
    35101 caaactttaa attaatgaat attgaatcgt cagatagcct cctcgagttt tcgagaaggc
    35161 tatcgtttat tttatggaga aattgattca gaagtaatca gcgacctttt ttagttcacc
    35221 aatcgtttct gcttggaaag tttgcaccca atcttcttgg aagcccctca ctgctttatc
    35281 aatcgagggc atctctaata cttgatctag tagctcttta cctaacgtta tcgctgagct
    35341 ccagatcgaa tggctgtagt gacttgttca caatttttga aactagctgc taatattttt
    35401 gttggtcttt gcgtacgttc gatctcagtc cgcaacgaat caatcacttt catagcatca
    35461 atgccttgat tttgcatcct gttataataa ggtgcaatat aatctgctcc attattaata
    35521 gctaaatacc cttgtaattc tgtgtaaata gctgtaccgg taatcaaata accttctttt
    35581 ttcaactttt tgatcgcttg aaggcctgct tgattcaccg gcaccttgat aaacgtatct
    35641 tttcccagtt cttctatgat aactcgagca tcctctatca tttcttcttc cgttcttcct
    35701 attgtctgaa tatggatagg aatctgtccg attatttttt tgatttcttt catatgcgag
    35761 aagaagtttg acgctccttc ttttttcaga attgtaggat ttgttgttac gcctgttaaa
    35821 ttcaaaaact gttgacaaga ataaatactt tttgtatttg ctgtatcaag catgatttcc
    35881 atatagcttt cccccattct gatcctcttg atcgatttta atgattgtcc cctttcttaa
    35941 atgcggcatt tccttatctt ctacatacat tgttcctgga agttccggct catgagatcc
    36001 atcaaatttt atcgtgatat gtcctaattc attcaaatta gtttggacaa catctcctac
    36061 tgctgtgatt acatacattt gtttatcaaa acagagcttc atatcacaag ttatttcttt
    36121 tcttacctga ttcaattcaa tcttataaca ataatctgtt aatgtttccg gtgcttcatc
    36181 tccaaataaa atcattattt tttctttcct gaatacttct gcttctatac caacatctgt
    36241 tacaaccgtt tcaaagatcg tcatctctgt tcctcctcgt aaaatatcat ttgtctaata
    36301 gtttttattc aaaatgtttc tagattataa aatttattga ataacacatt cctaacggaa
    36361 tttgtttcga tattgtgtga tttctcagag tacaatggat gtatgga
//
LOCUS       DAFENC010000026        34959 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.026, whole genome shotgun sequence.
ACCESSION   DAFENC010000026
VERSION     DAFENC010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.026"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            153..1859
                     /gene="efbA"
                     /locus_tag="LP493_001667"
     CDS             153..1859
                     /gene="efbA"
                     /locus_tag="LP493_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HBL2133821.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2017..2919)
                     /locus_tag="LP493_001668"
     CDS             complement(2017..2919)
                     /locus_tag="LP493_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL2133822.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2916..3608)
                     /locus_tag="LP493_001669"
     CDS             complement(2916..3608)
                     /locus_tag="LP493_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HBL2133823.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            complement(3651..4292)
                     /locus_tag="LP493_001670"
     CDS             complement(3651..4292)
                     /locus_tag="LP493_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBL2133824.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4330..4644)
                     /locus_tag="LP493_001671"
     CDS             complement(4330..4644)
                     /locus_tag="LP493_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133825.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(4632..5984)
                     /locus_tag="LP493_001672"
                     /pseudo
     CDS             complement(4632..5984)
                     /locus_tag="LP493_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372436.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
     gene            complement(5981..6913)
                     /locus_tag="LP493_001673"
     CDS             complement(5981..6913)
                     /locus_tag="LP493_001673"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBL2133826.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6910..7686)
                     /locus_tag="LP493_001674"
     CDS             complement(6910..7686)
                     /locus_tag="LP493_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HBL2133827.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7740..10925)
                     /gene="carB"
                     /locus_tag="LP493_001675"
     CDS             complement(7740..10925)
                     /gene="carB"
                     /locus_tag="LP493_001675"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBL2133828.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(10930..12006)
                     /gene="carA"
                     /locus_tag="LP493_001676"
     CDS             complement(10930..12006)
                     /gene="carA"
                     /locus_tag="LP493_001676"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBL2133829.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(12011..13291)
                     /locus_tag="LP493_001677"
     CDS             complement(12011..13291)
                     /locus_tag="LP493_001677"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HBL2133830.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(13310..14236)
                     /locus_tag="LP493_001678"
     CDS             complement(13310..14236)
                     /locus_tag="LP493_001678"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HBL2133831.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(14249..15532)
                     /locus_tag="LP493_001679"
     CDS             complement(14249..15532)
                     /locus_tag="LP493_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HBL2133832.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(15546..16085)
                     /gene="pyrR"
                     /locus_tag="LP493_001680"
     CDS             complement(15546..16085)
                     /gene="pyrR"
                     /locus_tag="LP493_001680"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HBL2133833.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(16320..17231)
                     /locus_tag="LP493_001681"
     CDS             complement(16320..17231)
                     /locus_tag="LP493_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBL2133834.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(17228..17692)
                     /locus_tag="LP493_001682"
     CDS             complement(17228..17692)
                     /locus_tag="LP493_001682"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBL2133835.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(17697..18395)
                     /locus_tag="LP493_001683"
     CDS             complement(17697..18395)
                     /locus_tag="LP493_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBL2133836.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(18382..18768)
                     /locus_tag="LP493_001684"
     CDS             complement(18382..18768)
                     /locus_tag="LP493_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133837.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(18915..20585)
                     /locus_tag="LP493_001685"
     CDS             complement(18915..20585)
                     /locus_tag="LP493_001685"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HBL2133838.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            20768..21001
                     /locus_tag="LP493_001686"
     CDS             20768..21001
                     /locus_tag="LP493_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HBL2133839.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            complement(21100..21531)
                     /locus_tag="LP493_001687"
     CDS             complement(21100..21531)
                     /locus_tag="LP493_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HBL2133840.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            21610..22023
                     /locus_tag="LP493_001688"
     CDS             21610..22023
                     /locus_tag="LP493_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HBL2133841.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            complement(22061..23209)
                     /locus_tag="LP493_001689"
     CDS             complement(22061..23209)
                     /locus_tag="LP493_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBL2133842.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(23331..23927)
                     /locus_tag="LP493_001690"
     CDS             complement(23331..23927)
                     /locus_tag="LP493_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBL2133843.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            complement(24127..26769)
                     /gene="alaS"
                     /locus_tag="LP493_001691"
     CDS             complement(24127..26769)
                     /gene="alaS"
                     /locus_tag="LP493_001691"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HBL2133844.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            27157..27588
                     /locus_tag="LP493_001692"
     CDS             27157..27588
                     /locus_tag="LP493_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2133845.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            complement(27633..28982)
                     /locus_tag="LP493_001693"
     CDS             complement(27633..28982)
                     /locus_tag="LP493_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBL2133846.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(29052..30215)
                     /locus_tag="LP493_001694"
     CDS             complement(29052..30215)
                     /locus_tag="LP493_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBL2133847.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            30344..30667
                     /locus_tag="LP493_001695"
     CDS             30344..30667
                     /locus_tag="LP493_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133848.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            complement(30850..32199)
                     /locus_tag="LP493_001696"
     CDS             complement(30850..32199)
                     /locus_tag="LP493_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2133849.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(32268..33221)
                     /locus_tag="LP493_001697"
     CDS             complement(32268..33221)
                     /locus_tag="LP493_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HBL2133850.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            complement(33323..34513)
                     /locus_tag="LP493_001698"
     CDS             complement(33323..34513)
                     /locus_tag="LP493_001698"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HBL2133851.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
BASE COUNT         9951 a         7640 c         6120 g        11248 t
ORIGIN      
        1 taaaaatttg gatttcaacg atagaaacac tgttttttat gtaattagtc caagattttt
       61 ctagactttt gctttactat tcggccaaat tggtttttct tctttttttc gttataatga
      121 atatacttat gaaaagaaat gaggaatgaa ccatgtcctt tgatggtgta tttacccacg
      181 cgatggtcaa cgaattgcgt gaaacgttac tatctggccg gatctcgaaa atccatcagc
      241 cttatgaaaa tgaaatcgtg ctggtgattc gttcacgcgg caaaaaccat cgattattat
      301 tatctgcgca cccaagttat gctcgtgtac agattaccca aatcgattat cagaatcctg
      361 ataatccgcc taacttcgtg atgatgcttc gaaaatattt ggatggcgct attttagaag
      421 acatcgaaca aatcgaaaat gatcgagtga tccatttcca ctttgctaaa cgaaacgagt
      481 tgggtgatct acaaaatatc atattgatcg ttgaattaat gggacgtcat agtacgatcg
      541 tcttagttaa tcgagaaact ggaaaaatac tggatgcgat caaacacatt ggaagctctc
      601 aaaacactta tcgttctttg cttcctggtg tagaatatgt tgctccgcca aaacaagagg
      661 tcttgaaccc atttagctcc gagaaagaaa aaatctttca gcggctttcc caaactgaac
      721 tagatccaaa agcaatccaa cgtcagtttc agggaatcgg tttcgatatc gctcaagagc
      781 tgaccaaaag attactggaa cgtcctaatg aaaagatggt tgtatgggac gaatttttct
      841 cagccatcag ccatcagcct attcctactt tttacgaaac ggaaaataaa gattttttca
      901 caccgattgc ttatcaggta ttgtccgaac aggcatctgc tgtaacagct tatccaacac
      961 tcagtcaatt attagatagc tattatcacg aaaaagcaga gaaagatcgg gcaaaacaac
     1021 aaggcggaga actgattcga aaaatcgaaa atgaactaaa acgaaataaa aataaattga
     1081 aaaaacgtga acaaacactc aaagaatccg aaaacgctga gaattaccgt agaaatggcg
     1141 aactacttac tacttttctg acacaagtac cacgcggcgc aaaagaagtt gttttaccta
     1201 attattatga agaagatcgg ccaatcaaaa tagcactaga tccggcattg acaccaaatc
     1261 aaaatgcaca gaaatatttc catcgatacc aaaagctgaa gaacgctgtt aagctgattg
     1321 gcgaacaaat ccaagaagcc aaagatgaaa tccaatatct tgaatctgtc ttatctcaac
     1381 tggaaattgc cggcccaatg gatatcgaag caattaaaga agaattgact tcagaaggat
     1441 acctgaaaaa gaagaactta aaaaaacaaa aacgtaagaa accatctcag cctgatcaat
     1501 acttttcttc tgacggaacg ctcattcttg ttggtaaaaa caatcttcaa aatgaccagc
     1561 tgacaatgaa gacagctaaa aaaaccgact attggcttca tgcaaaaaat atacccggtt
     1621 cgcacgtcat cattaaaagt gacaagccct cagatgaaac aattacagaa gctgccgagt
     1681 tagctgccta tttttcaaaa taccgatact ctgcccaagt gccggttgat cttgtacagg
     1741 taaagcatat ccgaaaacca aatggcgcca agcctggtta tgttatttat gaaaaccaaa
     1801 agacgattat cgtgacacca gaagaagaaa aaattacagc tatgaaacaa aacaggtaat
     1861 caatgagtgt ttctagaatc atatttgcgt actttcccac aacagcaatt agttataaat
     1921 tgtttgctac aaaaagagga gttgtgacaa aattctgtca caacccctct tttttgatca
     1981 acggtgttca ataaacagcg ttctcatctg cttttcttag ctctgctggt ccagtaaccg
     2041 agtaagctct ttgataaatc tttgagcgat ttcactgagc ggacgtttcg ccgaataaat
     2101 gatataaaat tcatttagtt cgccttctgc caaagggatt aaccgcaagt gctcgcgaat
     2161 ccctccaatc acaataccag atcctgaagc gtaagcatca gtttcaagaa cgatattcat
     2221 caaagtacct cgatcactcg tataaatcac tgtttcttga tcagggatct cgataaggtc
     2281 ttcataaaaa tacgggaaat tatttccatc ctgtgtaaaa cgaacttgag gataagataa
     2341 caattcttct ttggtgatct ctgcgtgttc agctaatgga tgtccttgcc ttaaaaaaat
     2401 atgcgttttg aattttccaa tgctgcggcc acttagctct ccttgttgta aatatcttct
     2461 gataccagct tgattatgct cattcatata aataatgccg atctcactgt gctgctcttt
     2521 gacttcttcg atcactctcg ctgttgtcgt ctccatgatc cgaaattgtt tgatctcgtc
     2581 tttgaattcc tcgagtagct gtgcggtcaa aggacctaag aaatcataat gctgggcagc
     2641 gatcgaaaaa ttgtctctct tttcactcgt tagatagtga gtttctaatg tatcaagctg
     2701 gaccaatatt ttctcggcac gatttaagaa gtcttgccct tcttctgtta aatatgcccc
     2761 tcgattcgtt cgagtaaaca gcgtgatccc taactcggtt tctaattctt tgataccagc
     2821 tgaaagactt ggctgggaga caaacatttt ctttgccgct tctctgaaac taccattgtt
     2881 tgctacagcg accacgtatt tcatctgctg aatattcatt gctcaaactc ctcgaaataa
     2941 taaatttctc ttccattcaa gggctggatt ggtcggttgt tcggtcgagc atactgacca
     3001 tcgaagggga gaagaaactc ttggttcagt tttcctacat gatccattac aaaccattgg
     3061 attggcccgc tggtaggcgg agttgtcaat gagccaatat aatggaaatg gcttttttgc
     3121 tccggaaaga acacatccgg atttacccaa tgctcatgtt tttctaagtt ccaactttcc
     3181 ccattttctt gattatacag ccaaccttcc tgtaccatta gctggtacat gacacccaca
     3241 actagattct cttttttgct gttcatatga acaaaatgaa attcaatatc ttcctgtttt
     3301 ccgttgatga tatgttcaga aggcaagtgg aaatgaatat ctgtcaaata atagcgttct
     3361 ttcttgaact ctacataact gagttggtca aaaggtacta aatgaatcgt gtttttgaat
     3421 tccttgtcag taaaccgttg cttttgataa tgaaaggaaa gcgtgtctcc ttctattttg
     3481 gtttcttccc ccttggtcaa atgaataggc gactgcaatg gaaattccgc acctctcgca
     3541 aaccaatcac ataaactcgc ccaattttcc ggacctttgt ctccagaata gccccattcg
     3601 acatccatat tctttttcaa ctatacttcc ccctgcatct catatcattt ttatttttct
     3661 tctttcttta caatcgttga gacggtttct aaaaacgcct cttttccata aaattcctgg
     3721 ttcaatagtt ccggaaatat ctctttaaag aaatactgaa cagaaggccg atgttcaaag
     3781 cttttaatcg tagtcactgc ctcaatgaac atctccttat aaactttttc cgggttattt
     3841 ttgatgattt catcaaaaga ttcataaaga aggtcaacct tatctgaaat ggctaatagt
     3901 tctccttcta cggtttcatc ttttccttcg aacaaccgac ggcgataaac ttcttggaac
     3961 tcagctggaa tctcttggtt gatgaattcg tccgtcatct tttcttcaac tgtttgcagc
     4021 atccctctta actctttgct tgcgtatttc accggcgttt tgatatcacc aataaaacgc
     4081 tctgtgtagt catgattcaa tgatttttca tagagcagtt tccaatcgat cggttgtcca
     4141 ttcgcttctt caatgtctcc tagaacttgc gcaatagatg ctacacgata cgaatgtgct
     4201 gcaactgtat gctctgtata tttaaaaaat ccaggtgccc ttgtgatcgt ctctaaattg
     4261 ttcaatccta aaataaattc attcaacccc ataaaagtta cctccctttg agatttcttt
     4321 ttccgaatat catatcatta aataactgat attcgcaaca tttccgctct ttaccatttt
     4381 tgaaacagct cccttaccaa aaaatagaga aaatctatat ataatagaaa aaagagaaga
     4441 gattattctc ttctttctgc taaccagtct tagaaaaatg aattttaaaa aaatcaaaaa
     4501 ctgatcacga tagaagtttc ttttcatacc tgatgaaaag atgcttctcg caatcagttt
     4561 ttggattttt gctattccaa ttgatgattc tggagacaca aatcggattt ctctatcttc
     4621 atcaagcgcg cttaaatctg ccaattttca ggatcttttt tccattcttt tagcagagtt
     4681 aattcttgct catcgatata acgatcttct aaagctgctt caatcaatac agaataattg
     4741 gtcaacgtca taagagggat ttcggctttt tcgaaatttg cttttccttt tggcaactca
     4801 tacgtaaaga tagccgcaac accaaggata tccgcacctt ctctttttgc tgcttcagct
     4861 gcttccaaga cacttccgcc tgtagaaatc aaatcctcga tcacaaccat cttctgacct
     4921 tcaaatatac gtccttcgat ttggttacct ttcccatgat ctttcgcctt acttcgaata
     4981 tagaccattg gcaaatccag tatttccgct acccatgcgg catgagggat tcctgctgtt
     5041 gcagttccag caatcacttg tacttcaggg taagcttctt tgattttgct tgctaatcct
     5101 tttgcgatct cttttcggac ttttggatag ctcatcgtga ttcggttatc acagtaaatt
     5161 gggcttttga ttccacttgc ccatgtaaaa ggattacttg gatttaaaaa tactgcttca
     5221 atttctaata agtcttttgc gatactttgt tcaacattca ttttaggtta gctccattct
     5281 gtttgaatcg tttgatatgc tttataagga ttagttgact gagtgattgg tcgacctata
     5341 acgataaaag ttgagccgat cttttttgcc tgagaaggtg tgactactct tgtctgatct
     5401 cctgcgactg ttccttctgg tcttataccc ggagttaagc aaacaaattc gtctcctgcc
     5461 atttctttga tcgcttctac ttcccaagca gaagaaacca caccatctaa tcctgctttt
     5521 ttggcacagc tagcataatg gatcacactt ttttctaaag aaacttcgat tagttgatcg
     5581 gcatgcattt cttcttcact tgtagaagta agctgagtga tagctagaag tagcggacgt
     5641 tttccacctt ctggagtccc ctcttctaat cctcgcattg ccgcctccat catacgaata
     5701 ccgccagcgg catgaacaca ggtgagatca acaccaagct ttgccaatcc ccgcattgct
     5761 ttttcgaccg tattcggaat atcgtgaagt ttcagatcta aaaatacatt atgaccagcc
     5821 tcttttagat aacgtacgat ttcaggtcct tcttggtaga acaattccat tccgattttc
     5881 acaaacaatt tttcttcttt cgggaaaaat cgaagaaagt cttctacctc ttgcctagtt
     5941 gaaaaatcta atgcaataat tggtcgttgg tctagttgat tcatcgttca cgttcctctc
     6001 tcacttcttt gattaatctt tccagcgatt cgatgcctag ttcgctcatt cgcacaggga
     6061 gctctttaat tagtttagga cagatatacg gatcggtgaa attcgcggtc cctatagcta
     6121 cagcacttgc tccagccata aacatctcaa gaacatcatc cactgtctgc acgccgccca
     6181 tcccaatgat tggaaggctg gatatacttg ctacttggtg aatcaaacga atagcgacag
     6241 gcttgattgc tggtccggag agtccacctg tttgattggc taaaatcggt tttcttgtct
     6301 taaggtcaat ccgcatacca agaagagtat tgatcatcgt aaacccatct gcccctccag
     6361 cttcgattgc ctgagcgatt ggaacgatgt ctgttacatt tggggacaat ttgacataga
     6421 caggaacaga agaaactttc tttactgctt gtgttaattg aaaagcaaca tcagaatctg
     6481 ttccaaaagc aattccgcca tgtttgacat ttgggcaaga aatgttcagc tcgattgctt
     6541 tcacatttgg tgcttcgcca attttgctac aaacttctac atagtcttct tcacaagcac
     6601 cagcaacatt tgcgatgatg ggtaactcat tgtactcctc taattctgga agaagtttat
     6661 gcataacaac gtctagacca ggattttgca aaccaattgc attcaacatg ccagatggtg
     6721 tttccgccac tcttggcgtg ggattgccaa agcgggcatt tggagtcgtt gccttgacca
     6781 tgatcgatcc aagctgattc aaatcatagt attttccgta ttctttgcca aaaccgaaac
     6841 agccgcttgc cggcatgata ggatttttta attctaggcc aggaagtttg accgctaaag
     6901 gattctcatt catataatta cctctcctat tttaaaaatc ggtccttcgt cacaaacttt
     6961 cacacttttt gttcctgttt catcttccgg cgtatgacaa acgcaagcat agcaagcccc
     7021 tatcccacat gccatgcggg attctaatga taactggaca ttttgatgcg aagaaaacag
     7081 ctgttccact gtcttcaata acccgtttga accacatgca aaaacagctg taggttccgt
     7141 cttcgttcct aacaataaat taccgacatt tccgtgcata ccgtatgttc catcgtcagt
     7201 agcgattctt gtttctccta gacgattaaa ttctttttca taataaacga cttcatgtgt
     7261 ggcaaaacct aaaaaatgcg ttggcttaat tcctttttcg actaactgtt ttgataactc
     7321 atatagagga gggacaccga ttcctccacc gattataaat acttcgtctc ctgtatgaag
     7381 attggacaaa tcaaaaccat tgcctaaagg acccatgaca tctaaatggt ctccggcaga
     7441 aagagtagag aagactctag tcccctcacc ttccacccga taaatgatac ggcaagtatt
     7501 tgtttcgtgg tcgatatgat tcaagctaat cggtcggcgt aatagcaagt ctgcacgcgg
     7561 cacgagaata tgcaagaact gtcctggttg ctgcatttct tttactagat cacctttcaa
     7621 tgtcatttca aaaatctttg gtgccagctg tttttgctga acgatttcca tcatttcttg
     7681 tttcatctgt cccctcctgc aacggttttt cgtctttttg tcttaacatg tgctcgccgt
     7741 taaatagggt tagttgaaaa agcacgggat tccatcactc gaacgatcgc atctgctgtg
     7801 tctaaagaag taaacaatgg aataccatgt tcaactgctt ctcttcggat gatgaaaccg
     7861 tctttagaag catttccccg atctttatca atcgtattga caaccacttg tgttttacca
     7921 tctcttatta agtcgactac atttttttct gctgcttcct cagaaatttt cgctactgtt
     7981 tcaacgacca gaccattttt ttcgaaataa gcagctgtat gtttcgttcc tatcagacta
     8041 tagccaattt ctgtaaaacg tttagctaat tctagtgctt cttcttttgt ttcgtccgca
     8101 atcgtaaata atacggctcc atattcaggc aagtgtaatc cagaagcttc gaatgccttg
     8161 tacaaagctt tgtctaattg tctgtcagat cccattactt ctccagtcga tttcatttca
     8221 ggccctaagt aagtatcaac tttctgcaat ttcgtaaaag aaaagacagg tgctttaaca
     8281 tgaacttctt ttgtttctgg ataaagtccg ttttcataac caagtgtctt tagtttctct
     8341 cccaaaatag ctttcgtcgc aatttgtgcc attggaattc ctgtcacctt acttaagaat
     8401 ggaacagtcc gacttgctcg aggattgact tcgatcacat aaacctcatt ttcatggatg
     8461 acaaactgga tattcatcat cccgacacaa ttcaaaccta atgctaagcg gatcgtgtaa
     8521 tcttcgatcg ttttcttgat cgattcagat aatgtttgag gtggatacac agccattgaa
     8581 tcccctgaat ggacaccagc acgctcaata tgctccatga tccctgggat gagtactgtt
     8641 tcaccgtcac aaatcgcatc cacttcgcat tcaccaccaa gcaagtaacg gtccactagt
     8701 actggatgtt ctggagatgc tttcacagca tgttccatgt aatcttctaa atctcgctgg
     8761 ttttcaacga tttccatcgc acgtccgcct aatacatagc ttggacgaac aagaactgga
     8821 taaccaattc tcgaagcgat aaccacggct tcttctttac ttgtagcagt atcccctaaa
     8881 ggttgaggaa tatccaactc tttcagcgct tgctcgaata aatcacgatt ttccgcacga
     8941 tccaagtctt cgatcgttgt ccctaagatt tttacaccag cagcagtcaa aggttcggct
     9001 aagttgattg ctgtctgacc accaaattga acgattactc ctatcggctg ttctagctcg
     9061 atcacattca tcacatcttc gaaggtcaat ggctcaaaat ataatttatc cgaaatagaa
     9121 aagtcagtcg aaactgtttc aggattgctg ttcatgatga ttgcttcgta tcctgcctgc
     9181 tggattgctt tgacagaatg cacagtcgca tagtcaaatt caaccccttg tccgatacgg
     9241 ataggaccag atcccagtac tagaattgag ggcttttctg atcgtgaact ttcattttca
     9301 tattcatagg aactataaaa ataaggtgtt tttgattcga attccgctgc acaagtgtca
     9361 accatcttat atacaggaat caaatcattt tcttttctca tctggcgaac ggcttcttcg
     9421 tttatttccc acagctccgc cacttttttg tctgtaaaac cgttttgttt cgctgttttc
     9481 aatatcttgt catccaacgg ctgctgtttc aactgctgtt cgatttctac gatatgcaac
     9541 agtttatcta aaaagaataa atcgattttt gtcaaatccg ctaattcttc tatggtgtac
     9601 cctcttctaa tagcttcagc tacataaaac aggcgatcat cttgtgctcg aaccactttt
     9661 tggattaggt catcgtccgt gatgtctgcc aactcaggaa gttcgatatg gtgtgtaccg
     9721 atttctaaag aacgcacagc tttcaataaa gactcttcga tattccgacc gatagccatc
     9781 acttcaccag ttgctttcat ctgcgtgcct aaaagccgtt ctccgttttc aaacttatca
     9841 aacggccagc gaggaatttt agctacaaca taatctaatg caggttcaaa ttctgcaaaa
     9901 gtcgttcctg taacaggatt tttcatttcg tctaatgtta atccaagcgc tattttagca
     9961 gctagcttag cgatcggata gccagtcgcc ttacttgcta acgcagatga acgagaaaca
    10021 cgcggattga cttcaatcac ataataatta aaactatgtg gatcaagagc gagttggaca
    10081 ttacagcctc cctcgatctt aagtgctcga ataatcgaaa gagaagcatc acgaagcatt
    10141 tgatattcat ggtcagacaa tgtttgacta ggggcaaata cgatagaatc acctgtatgg
    10201 atacccaccg ggtcaaaatt ttccatattg cagacaacga ttgcattatc agccgaatct
    10261 ctcatcactt catattcaat ttctttaaaa cctgcaatac ttcgttcaat caaacattgg
    10321 gtagcggggg aaagacttaa tccattttct gatacgatac gtaattcttc ttcattttca
    10381 cacatacctc caccagttcc gcctaaagta aaggctggac gaacgatgac aggatagccg
    10441 attttatttg caaaatctac agcttcttct actgtattga cgatttcaga ctcggggatt
    10501 ggctgattca attctttcat caactgtttg aatagatcac gatcttctgc ttgatcgatc
    10561 gcagaaagct ttgttcctag aagttctatg ttcaattctt ctaaaatacc tgatgctgcc
    10621 agctccattg ccatattgag gcctgtctgt ccgcctaaag ttggaaggag agcatctgga
    10681 cgctcttttc gaagaatcct tgatacaaat tcaagtgtga tcggttcgat atatacttga
    10741 tctgccactt ctttatccgt catgatcgtc gcaggattag aatttactaa aaccacttca
    10801 tatccttctt cttttaaggc aaggcaggct tgtgttcctg cgtagtcaaa ttctgcggct
    10861 tgaccaatga tgatcggacc agatccaatc accataattt tcttgatatc tgtacgtttc
    10921 ggcatctgtt tactgctcct ttcctgcgtc catcatttcc ataaattcat caaataaatg
    10981 tagtgcatca tgcggaccag gggcagcatc tggatgaaac tgcacactga aagcgggata
    11041 atctctgtgt ttgactcctt ctactgttcc gtcatttact tctacatgag ttacgatgag
    11101 tttttctgga tcaatcgtgg cttcatcgac tgcatagcca tgattttgag aagtaaaatc
    11161 aattcttccg gtcgctactt ctcgtaccgg gtgatttaat cctcgatgtc cgaatttcat
    11221 tttataggta tctgcaccgt tggctaaagc aaataactgg tgaccgagac aaataccaaa
    11281 aatcggtact tttccttgga tttttttgat catttcgatt gcttctggca catcttttgg
    11341 atcaccaggt ccattcgtca gcatgactcc gtctggtgat agcgctaaaa tcgtctcggc
    11401 atctgtgtta tagggaagta ctgtgaggtt acagtttctt ttactcaatt ctcgtaaaat
    11461 actatgtttc aagccgaagt caatgacaat gactttccga cctgttcctg gacttggata
    11521 aggtttgtta gttgagactt gctgcacttg attggttgct agaacggttg ctttcagctg
    11581 atcaaatgca tgttcgaagg aatctccagc atcaactata ctagctttca tcgttccgac
    11641 ttcacggatt ttgcgagtaa gggcgcgcgt atcgatacct gatattccag gaattccttt
    11701 ttgtttcaaa aatgaatcta gcgtcatttg gtttcgccag tttgaagcta cacgtgcatg
    11761 ttcttttact actactcctt tgcatgttgg agaaatcgat tcataatcat ctctatttac
    11821 cccataatta cccaccatag gataggtaaa tgtaatgatt tgaccgttaa aactttgatc
    11881 agtgatagtt tcttgataac cagtcatact tgttgtaaaa acgatttctc cgaagacact
    11941 agcatctgca ccaaaagcct ttccttcgaa aactgttcca tcttctaata taagcaaacg
    12001 ttccatactt ttattctccc ttctgccaca caagttttcc gttgacaaaa gtcatttgtg
    12061 tttcgccttt tactttccag ccgataaaag gtgtattctc cccttttgat aaaaagtctt
    12121 ctttatcgat cgtgcaagtt tgtgtaatat caaaaactgc tacatcagcg ggggcaccaa
    12181 ccgttagcgt tcctgcattc aaaccaaaaa tctcagccgg tttaactgcc aaccaattga
    12241 tcacttgttc caacgtgaat cgaccagttt ctacaaaatg agtatagatc agttgaaacg
    12301 ctgtttcgct tcctacgata ccaaatggtg atttcatgaa actttggctt ttttcttcta
    12361 atccatgggg ggcatggtct gtagcgatgc aatcgatcgt accgtcaagc aagccttcga
    12421 tcaaagcttc tctgtcctcc cgtcctctta gcggcgggtt cattttccaa aagccgaaat
    12481 cttcgggaat atcttcgtcg atcaaaataa gatgatgggg tgaaacttct gctgttacgt
    12541 ggattcctgc tttttttgcg tctctgatta cacggacact ttctttagta gaaacatggc
    12601 aaacatggta atgaacacca gttgcttcag ctagcaacag atctctagca atttgagaag
    12661 actcggttac gcttaagatc ccgggaagac caagttcttc tgccttcttg ccagcgtgca
    12721 taacgccgcc aaataataaa gattcatctt ctgtatgggc tactagggct ttattgtttt
    12781 ttgcagcttc tttcatagcc agatacatcg tcccagctgt ttggacacct acaccgtcat
    12841 ttgtgaaagc aaaagcacct tcttcaatca gtgcttcttg atcaactaat ttctcacttc
    12901 gcagattttc tgtgattggc gcatactgca ataccttcac aactgcatct tttctaatga
    12961 tgtcatatac ttgtctcagc ttttctgccg tatcaggtac aggatttaaa ttcggcatcg
    13021 cgcatacagt agtgaaaccg ccacgagcag ctgagcgagt cccagcttcg atcgtctcct
    13081 tgtatgtaaa tcctggctct ctcaaatgaa catggacgtc cactaaacca ggtgtgatca
    13141 attgtccctt tgcatcaaac acttcatcaa attcggcttc tgagaatcct gtaccgattg
    13201 ctttgattcg cccatcttct atccaaattt ctgctggtgt cgtcatattt tttcgtgtat
    13261 tgatctgacc gtttttaatg agtgttttca ttttttcatc ctcctataat tacgcttttc
    13321 catttagcac tgcttctaag attgccattc tgacgaatac tccattgctc atttgctgaa
    13381 cgatccgcga ctgtaatcct tccactaatg aatcagctaa ttctacatca cggttaactg
    13441 gtgctgggtg cataatgatt gcatgttttt gcaacttctt cgcacgctca actgttaacc
    13501 catgttcctg atggtagcct tcttttgaga aactttcttt tccatcatgg cgttcgtgtt
    13561 gcacccgaag catcatcatg acatcaactt gatctagtag ttcatccaat ggcatataat
    13621 gtccgtacac ttcgaattca tcgtcgtacc attctctagg acctgagaag aatacttgtg
    13681 cgcctagacg ttttaacatc tgcatattgg atttagctac gcgagagtga gtgatatcac
    13741 ctacgatggc aactttcaga ccttcaaaat gaccaaattc ttcataaatg gtcatcaaat
    13801 caagcaagca ttgggttgga tgctgtccgc ttccgtctcc tccattgata atcgaacact
    13861 ggattgtttt actttgtatc agttcgtcat aatagttctc atcaccatga cggataaccg
    13921 ctacgtctac gcctaatgct gacatcgtca gtactgtatc gtatagtgtt tccccttttt
    13981 ggacagagct tgtgcttgct tcaaattcaa tcacttctag ccctagtttt ttctccgcta
    14041 catcgaagct tttatgtgtg cgagtactat tttcgaaaaa gaggtttgta gcaaagtact
    14101 ggcgcttttg cggagtccaa ttagcacctt gcttgaattc ctgccctctg cggatcaagc
    14161 ccataacttc ttgatcagta agtgcctcaa cggtcaataa atgctttaag ctgatacgtt
    14221 ctgatttgat gatcataatg tttcctcctt agttttcttc gcttcgtgaa gtttctggta
    14281 agataagatt taaaatgatg ccaagtacag ttgctaatgc cattgccgac aatgtaaatg
    14341 tgcctacttc aaagacgagt ccgccaattc ctactactaa gataactgaa gcaatcaaca
    14401 gatttttctt tttatcaaaa tcgattttgt tctcgattaa aatcttcatt ccacttgcgg
    14461 caattactcc aaataagata aaactgattc ctgagatgac tggtccaggg atacttaaaa
    14521 tcaaagcgct taattttcct acgaatccta aaatgactgc aaatactgca gctccaccga
    14581 tcacaaacac gctatggaca cgtgtgatag ccagaacacc aatgttttca ccgtaacttg
    14641 ttacaggagg acctccgaca aaggctgcca cgatttgtgc taatccatca cctgtcaacg
    14701 tcttatgaag acccggttct tcaaagaaat tacgtttagt tagtttattc aataccataa
    14761 gatggccgat atgctctgtc atcgtcacaa aagcgatggg tgccattgtt gtgattgctc
    14821 caagatatag ctttggttca tattgtacaa agggaatctc aaagttagga acagcaaacc
    14881 aggcagcgtc tacgattggc ttagtatcca cgattccaaa cagcaaggct acgatgtatc
    14941 cgctaataat acctagtaaa atcggaatca atccgagaaa acctcttagc cacatgttga
    15001 agaaaattgt taatcctaat gtgatcagcg ctacagcaat atacttgaaa tcatacgtgc
    15061 cctgattata catagcattt gttgctgcat ttgccgcaag tcccaacccg ataaccatga
    15121 tgactggacc gacgacgatt ggaggcaaga ttttatccag ccatgctgaa ccgatctttt
    15181 tgatgatcag cgcaacaatc aaatagacta atccagttgt gactgctcct tgtgcaatcg
    15241 ctggataacc atctgttttc atcaaaagct gcatcgctgc aatgaaagcg aagctgcttc
    15301 ctaagtacgc aggtatcttt cctttagtag taaataagta caccaatgta cctagtcctg
    15361 aactgactag cgcaatacct ggatcgatac ctactaagat ggggactaac acggttgctc
    15421 cgaacatcgt gaacaagtgt tgtaaactta atcctaccca atgtcctggg gttgggcgat
    15481 cgtggatatc taacaccacg tcatcattat gaaatccttt tttctccgac atgtttctct
    15541 ctcctctaat cttcctcttt caaaatcatg atgcgatctt gtccatcaag ctcttgcatc
    15601 tctactaaaa tctcttccgc ccgagatgtt ggaatgttct tcccaacata atctgcacgg
    15661 attggcaatt ctcgatgccc acgatcgacc aggactgcta atgaaatttt tcttggtctg
    15721 ccaaaatcca ttactgcgtc cattgctgct cgaatcgttc gtcctgtata caaaacatca
    15781 tcaatcaaaa taacttcttt tccttctaag gaaactggga tgtcagaaga atgaagttcc
    15841 ggttcttctg gattttcttt tttgtcatct cggtataaag tgatatccag ttctcctaca
    15901 ggaatatcga tatcttctag ctgcttcagg cgttcggcaa ttcttgatgc aatgtagatt
    15961 cctcgtgttt tgatacctac caatacgata tcttggatac tatggtttct ctcgataatc
    16021 tcataagtaa ttcgagtcaa tgctcgcttc atggttacct gatctactac ttcttttgct
    16081 tgcattttca ttccccctac ttttttgcat aaaaaaactc ctgccctaag aggacaggag
    16141 gaatgtttag actgagcgta tactgataca ctgatagcta tactatgtca atgagcaatc
    16201 tacttatggc gcaccatacg tatccttgct cccacccttc ttagcctcac gggactaaac
    16261 ttaaaggaat tctattaagt tttatgcttt cgttgttaat tactataccg ttatctaaat
    16321 taaaatgcaa tgttttttct taatttttct aaagtttttt caaaaacttc tggaagaggt
    16381 gcttcaaaga tcatcttttc gtttgtagtc gggtgcgtaa aacctaacat ttgcgcatgg
    16441 agaaactgac cattgccttt caaagttttc ttcggtccgt atactggatc tccagctaac
    16501 ggataaccga tatacttcat atgcacacgg atctggtgtg ttcttccggt ttctagtttt
    16561 aattcaacca gagtaaatcc ttcgaaacgt tccaatacag taaaatgtgt gacagccgac
    16621 ttcccatctt ctcttatcgc ctgcattttc cggttttcct tcgaacggcc gattggcgca
    16681 ttgatggttc ctttttcgtg aggaatctct ccatggacta aagcaacata tttgcgcaaa
    16741 gaggtcttat cttttaattg ctgagctaat gattcgtgtg cctggtcatt tttggcaacc
    16801 attagcagtc cggaagtatc tttgtcgatt cggtgaacaa tacctggacg aataacgccg
    16861 ttgatcgtag aaagatcctt gatatggtac atcagcgcat tgaccattgt gccatgcgta
    16921 tgacctgctg aaggatgaac gaccattcct tgaggtttgt ttatcaccgc tacatcttca
    16981 tcttcgtaaa cgatcgtcaa cgggatattt tctgggacca catctaatgt ttctggttcg
    17041 gggatcaaga cagtaatctc gtctccttgt tttactttgt aatttgcttt gactggctgt
    17101 ccattgacag aaaccgctcc atttttcagc cacagctgaa tttgcgaacg actgtaatcg
    17161 gtgaataaat tagtcaatac tttatcgatc ctaccagatt catggtgaat cgtcgtttta
    17221 agttctgtca tttttttctt tgatcctttt catctaaaat aatataaatt aacatacaaa
    17281 tcactccaca tacaagtgtc acatctgcta cgttaaaaat cggaaagctc ataaaatctg
    17341 tctggaacat atctactaca tagccaagac gaatacggtc gataaaattg ccaatcgcac
    17401 cagctagaat caaactcaat ccaatcatga accagcgatt acctttttca cgatttttaa
    17461 tcatcaatgt gagaatcaca acgactgcaa tgagtgtcac tatagtaaag aaccacatct
    17521 tcccttctag catactccat gcggctccag tgtttcgaat atgattcagt gacaaaatac
    17581 ctggtataag atttttcgtc tctccaagcg ctagattatc agtgatccac catttgacca
    17641 actgatccac tcctactagc aaagcgctga atatccaata aataattaac aaaaaatcaa
    17701 tccttttcta tttgtttata aatatcacga ggtcgtacga tcccgagcag attaccatcg
    17761 ggattcccat ctttagtgat aagtacggct tccaaagtcc cttgctcacg aaacatcgct
    17821 tcaacctcgt aaatatgtgt tttagctgga acaaaatgat aatttgtgta ctttccgttt
    17881 tggatgatca aatccaacgc tcgtttattt gttaaatcaa ccggaccttt ttggctttct
    17941 tttgctagcc aaaacccgat attacgtaaa gtaatcaatg ctacaaattt tcctttattg
    18001 tataacggaa attgtgaata ccttttttct gctactatct ttaacagttc aagtaacgga
    18061 agatcttgtt caaaacctgt tacacgtttt gcaaatcgag gcagcacggt ttcaggctga
    18121 atcagttctt gttcgatcag ctggattcgc ttgactgtcc aatcatttgg ctctgcaatg
    18181 acaaaatcga ctgcgatccg atcatggacg atcgcattcc ttaactgagc aagctgtaaa
    18241 agatcatctt cgtattttct gatcattaat tgttttcttt gagctaggcg tctgacaagt
    18301 tcggtaaatc ccatatttcg tgcatttccc atctcgtctc tcatccattt ttcgattcga
    18361 ttgaaactga ttaaaaaaag atcagagttt gccataattt tcctccttga tcaaatatgc
    18421 ccggtttttt atatagaaaa agaacgcaat caacacaata actgcaaaaa aactgaaaaa
    18481 taaattttgt aggaaaacgg cccccaaccc agttgctaga aataaaaacg gatagatttg
    18541 aagaatcaag taattcattg tgatcacata agcaggcttt gcttctttca ctgtataaac
    18601 ggggcttttt agccaataaa aggtgacctg catcgtaaag ggcacttcca gatcaagcgt
    18661 tatcttttgt tcatgactga gaacactgcg tttttcattg ttgattctta gctgaatcga
    18721 gctacccata ccgtaaaaac cggtttttct tataaatgtc gttttcatca taccctccta
    18781 ttatgcttta gtatagctca aaatacaata aagaaaaaga atgatcctag tgtaaacaaa
    18841 attaattccc tatcgtctaa aaaaagaagc tgtagtcaaa atacagctcc ttcgatggta
    18901 gattataatc aagcttaaaa caatcccaac acttctccgt catttgtcac gtccatattc
    18961 aatgcagcag gttttttagg caaaccaggc atcgtcataa catctccagt caaggctact
    19021 aaaaatcctg cccctaattt tgggatgatt tcgcggatcg tgatggtgaa atcttccggt
    19081 gcacctagca gtgaaggatc atcagaaaat gaatactgtg tttttgccat acaaatcggc
    19141 agtttgtccc atccattctt cgtaaactct tctatttgtt tttgcgcttt tttgctgaaa
    19201 acaacaccat ttcctccgta aattttcttg acgattgttt ctgtcttttc ttgtatcgtt
    19261 tcttctaggc ggtataatgg cttgtaatta gcttcttttc tatcaatcaa tcgtactaca
    19321 gcttttgcta aatcaacgcc gccttctgct ccatctgccc atacactcgc tctcttggca
    19381 agaatcccct gattttcaca caagtgctcc aacagtgtga gttcattgtc tgtatctgtt
    19441 acgaattcat tgattgcgac gatcacaggt agctgatatt gttccatatt acgtatatgg
    19501 cgctttaaat ttgcaaaacc tactttcaaa gcatcaagat tctcattttt aagttcatct
    19561 tttttcattc cgccatgcat tttcaatgca cggacagtgg cgacaatcac cacagcatcc
    19621 ggcgcttttt tcaagttagg tactttgata tctaaaaatt tctctccgcc aagatctgca
    19681 ccaaatcctg cctctgtgac aacgtaatct gctaatctca atgctgtctt ggtagctaaa
    19741 atactattgc agccatgagc gatattggca aacggtcccc cgtggacaaa agctggtgtt
    19801 ccgtaaattg tttgtacaag attcggcttg attgcatctt tcagcagtaa tgccagagcg
    19861 ccttctgctt tcaagtctcc agcagtcaca ggctgacggt caaatgtata gccgacaacg
    19921 atccttgcaa gacgagcctt taaatcttca aggtctgccg caagacacaa gatagccatg
    19981 atttcgctgg caactgtgat atcaaaccca tcttctcttg gaacaccttg gattggccca
    20041 cccaagccaa caattacttt acgcagttca cgatcattga gatcgactac ccgtttccaa
    20101 atcactcggc gggcatcgat gttcaattca tttccttgat gaatatgatt atctaaaaga
    20161 gcagataatg cattattagc tgttgtgata gcatgcatgt caccagtaaa atgcaagttg
    20221 atatcttcca taggcaatac ctgtgcatat cctccgcctg cagcaccacc tttgattccc
    20281 atcacaggac caagtgaggg ttctcgcaat gcaataacag attttttatt gattttattg
    20341 agcgcgtctc ctaaccctac agtgatcgtt gactttcctt cgccagctgg tgttggattg
    20401 atggaagtaa ctaagatcaa atgcccctca gcgttatcct ttgatcgatt gattccagaa
    20461 aaattgattt tcgccttata tttcccatac agttccaaat cgtcttcctt aagatctaat
    20521 ttactagcca cttcaacaat cggttctagc tctgtttctt gtgaaatttg cagatcattc
    20581 ttcatttgat tacccctttt cacgaacttt attcaacaaa atatcttctt tgttaagata
    20641 tgccaattat accttttttt attcagaaaa aaaacataaa attacaggtt tttaatttat
    20701 ttgacgtact tataaatact ctttataatg aaggctatga tcagacttta gaaaggtcgt
    20761 gagtgctttg accacaggaa ttgtaaaatg gtttgacaac aaaaaaggat acggctttat
    20821 cagttatgat gacacagaag aaatttttgt acattttact gcgattgaag aagagggatt
    20881 caaaactttg gaagaaaatc aagtggtcga atttgagatc atcgaaggga atcgaggaac
    20941 acaagctgcc catgtcaaga aaggcaacgt tcagactacc gatactagta tgcatgaata
    21001 gataaacaaa tagagtgaga cgctaaacgg gatgaaccgt acgtctcact cttttctttt
    21061 cctgtaaaaa ttcgtttttt taggttctga tttttaaaat tagctttttc tttttttcgt
    21121 ataaggataa ggaattgatt ctgatttggg tccgtttttt tcaaaatgat caaaaaggac
    21181 tacttgatct ttttttcgca tcatgaaaac agatggggct ttctcatctt gcaacatcat
    21241 ttgcacccca gtattagttg gcgtcaaaga tcgaatctgt ccgacagata tttctcggtc
    21301 tttccaaaaa gcagcataac gtataatcac agagtttgat tttaaaataa aagaacgccg
    21361 caaacctaga aatagaaaaa caagaaaaat acctaaaaca aaattgcttt tccaataagg
    21421 acctgtgttt tctaaagaaa gaatcagact aaaaaacaga atgatcaagg tcaatgacca
    21481 atagatgatc gtatgtgcca gttcaggctg ccatcgaata ttttttttca ttctctaacc
    21541 tctcaccgat tcagtaatga tataatctta ccataacatt agtttgaaca aaaaggagaa
    21601 tctcttttta tgttaaaagt atacattgat gcctctacaa aaggcaaccc tggtcctagt
    21661 ggaggtggaa tcttgattgt ctatcaaggt aaacaagaac agctatctat cccgctttct
    21721 atagggacaa accatcaagc agagttcgaa gtctttttaa aaactttaga atttctaaag
    21781 aaaaacgact tacagaatga aacgattttc tgtttttcag acagcaaaac actagtttct
    21841 acggtcgaca aaaacgcaac gaagaacgag ctcttccttc cctaccttca aagaatccaa
    21901 gaacttctat ccgaattttc tttattgatc ctgcaatggt tgcccgaaaa caaaaataaa
    21961 ggagcagata atcttgcacg tcaggctctc cataaacaat taaaagaaaa aaagactctt
    22021 taaattaaaa actttaagga gtctttttat agtttctcat ttaatataaa agataattgt
    22081 gatcaaacgt aatttccaat tggtaatctc cgattttttc ttctatttga ctacgtaaga
    22141 ttctttctag ttctgtatca acaaactgga atttctcagg gaccactaca tcaaattgca
    22201 gcgtttttcc ttgatgaatt actctaaaat catgaatatt aagccctgta cctgtttcaa
    22261 gaagaatttg ctttaactgc cgcaagatat tatagtattt ttcgttatca acaggcattg
    22321 gatccaagtg acagacaagt tccacatcca aagacttttt aaagtctttt tctatcagat
    22381 caataatctt atgagccaca ttcaaattca ttgattcatc tacttcgatg tggactgatg
    22441 caaagcgttt attgggtcca tagttatgca ccaataaatc atgatagcca agtatatcat
    22501 cgcaagcatt taaatgctct tccatttctt caatctctgc tggcgttggg cgacttccta
    22561 atagttcgta tacaaaattt cgaagcatcg tcaatccact ataaaggata tataatgcta
    22621 aagcaaaacc tatatatcca tcaatacgcc atccagttac ccattcgatt gctgctgaaa
    22681 gcaatacagc cagtgtagta aagacatcat tataactatc tgttgctgta gctctcaatg
    22741 tttcagaatc aatggattgc gcaataacct gatacatttt gccttgtgca aatttcaaaa
    22801 agatggaaat gattaggaca aaaaagacga tgggtgttaa agagacattt tctggatgga
    22861 tgattttttc agcagaagac tctaaaaatt gaaatcctac ataagtaatg atgatcgaaa
    22921 caaataaccc actgatatat tcgaagcgtt cgtgtccata aggatgttcc tgatctgctg
    22981 gctttgcagc aattttaaat ccgatcaaag tcaatatgga tgaagcagta tctgatagac
    23041 tgttcactgc atcagccata atggagacac ttcctgaaaa aagcccgatc attagcttag
    23101 agacaaacaa gatcagattc gtaaccaatc ctaagatacc cgctagtact cctttttttg
    23161 tccgctgttg cggtatttgt ttcttttttt cttcttgttt cttagccaag ttttttaccc
    23221 cttctagttt gcttgttgct caggtaaaaa gatggagagg acgattgttt tcctctcctc
    23281 tcttcctttt tctatctatc gtgcgtccta ttactattaa aagatggtca ttattctggt
    23341 ttcaacggtg ttgctgcaaa taacgctttt gctagtaatg gtgttatgat tcccgcacct
    23401 attgcttctg gtatcccatt gattgctgca acccctgcta aggttttaaa taaaagagca
    23461 gagtctacac cataggcatc tgccgttgca cctgtataaa ataatcccat gaatcctaac
    23521 actaagactg tattgaccaa tgaacccagt acccctgcaa aggctgagct gatcgttatt
    23581 gatttatttt tttgataaat ccagtggaaa accaagcctg ctactaagcc aacaagtact
    23641 ctgggaacta ccgagataat cggattcgtg aacactaatg tatcaaatgg cgttgttggc
    23701 atggcatagg cacgaacaat tgtagcgatt ccccaaaaca agccaatcac catgccatct
    23761 tttgggccta atactactgc agcaataatt actgtgatat ggataattgt taaactaatg
    23821 aatcctaatg gaataaaccc cagccaagga accatcgctt gtacgatgat gattgctaac
    23881 aagatcgcac gtaagactag tcgaaaggtc ttatttctac tattcatttt ttcacccctt
    23941 tttatttata ctaatcgtaa aaatttctgt cactttcgtc aactaaagac catccgaatc
    24001 cgaccatttg attagatgcg ccatccaatt gaaaaaagta tgagggcaag acttgtttgt
    24061 cttcgccccc ataatcatgt ttcgttcaat gtttgaactt ttgtttttct gtcaaacgta
    24121 aacgccctat tgttgcgcaa cccattcttt cgcagcttta agtgcatctg gaataccagc
    24181 aggatttttc ccgccagctt gtgccatgtc tggacgtcca ccaccgccac cgcctacttt
    24241 cggtgcgatt gctttaatca agtcgccagc ttttagtcca gcttcatttg attctttcgt
    24301 cattgccgct agcagactga cttttccttc ttgttcgttt gctaaaacaa gaatatctga
    24361 aatatttttt tgtttccatt ggtcagctaa ttgacgcagc tgattcatat ctttcacttt
    24421 tacttgtgct gcaatgattg tttttccatt gatcgtttct ggatctttga atacatcacc
    24481 agcttgttga ttcgctaact tgctagctaa ttgttcattt tccttttgta gctctcttac
    24541 ttgctgttgc aattgttccg cttttgaaac aacttctttc aattgaggtg atttaacaat
    24601 tgttgctact tgttttagtt gtttttcttc ttcttcaagt agttcgtacg cttctttact
    24661 tgttacagcc tcgattcgtc gcacgcctgc accaattcct gattcagaaa cgattttgaa
    24721 gattccgatg ttttctgtat ttgctacatg tgtgcctccg cacagttcga ttgaccagcc
    24781 gccaatattt actactcgaa cgtcatgtcc gtatttttca ccaaacaaag ccattgcacc
    24841 catgtttttg gctgtatcga tatctgtttc aattgtttca actgggatag cttcccagat
    24901 tttttcgttg acgattcttt ccatttcagc taattcatct gaagtgattt gaccaaagtg
    24961 ggtaaagtcg aatcgtaaat gtccaggagc gactaaagaa ccagcttgat ttgcatgctc
    25021 gccaagtact tctttcaatg ccttgtgcag tagatgggtt gctgtatggt ttttgatgat
    25081 ccgattgcgc atcgattgat cgatcaatag atgataggtt tgtccttcac tcattggtgc
    25141 ttttacttct acggtgtgca taaattgacc attaggcgct ttttgaacat ctgtaacaac
    25201 tgctacgatt tcgcctactt cattcatgat ccatccttga tccgctactt gcccacccat
    25261 ttctgcatag aaaggtgttt gatcaaagat catttgagct tcaccttctg cgacttcatt
    25321 caaaagagac tcacctttaa cgatgaccaa taattgacta tctgattctt gttctgtgta
    25381 tccaatgaat ttactttcta ctttgatatc tgtcaataaa gcagattgta cccccattga
    25441 tttttcagta ctgcgggcag agcgagcacg ttcgcgttgt gcatccattt ctttttcaaa
    25501 accagcatga tcaactttca gtccttcatc ttctgccacc tcttccgtta attctaccgg
    25561 gaagccatat gtgtcgtata gtttgaagat gtcttttcct gctagagtcg tcccgttttc
    25621 gttttttact tcttggatca cttgatttaa gatttccaaa ccttcattga ttgtttcatt
    25681 gaaacgttct tcttctgtac ggataacttt ttcaataaat tctttttgtt gaagtacttc
    25741 aggataataa cttaccatga tttccccaac aacagggact aaacgatata agaatgcttg
    25801 ttcaatacct aattttttcc catgcatgac agcacgacga agcaaacggc gtaagacata
    25861 ccctctccct tcattcgatg gcaatgcacc gtcgccaata gcaaatgaaa gggcgcgaat
    25921 atgatctgcg attactttgt aagaaatatc tgttactggg ttttcaccat attttacttg
    25981 tttgcttagc ttttctacgg cgtggataat aggcataaac aagtctgtct caaagttcgt
    26041 tgacgcatct tgaacgattg agaccatgcg ttccaatccc atccccgtat caatgttttt
    26101 atgaggaagt ggttcaaatg tgttatcagg cttatggttg aattctgaaa atactaagtt
    26161 ccagatttct aaataacgtt cattttctcc tcctggatag ttttcaggat cgtcttctgc
    26221 taaatcgtta taagcttctc cacggtcata gaaaatttcc gtatccggac cacatgggcc
    26281 tgcaccgata tcccagaagt tgtcttctac atcaataatg tgatctagtg gcaggccaac
    26341 ttcttcatgc cagatgcgtt ttgcttctgt atcttttgga taaactgtta cataaagttt
    26401 ttctggatcg aatgccatcc attttggatc agtcaaaaat tcccatgccc agtggatggc
    26461 ttcatttttg aaatagtcac caatcgaaaa attacccagc atctcaaaca tcgtatggtg
    26521 ccgtgctgtt ttaccgacat tttcgatatc atttgttcga atagattttt gggcatttgt
    26581 gattcttgga ttttctggca caactgaacc atcaaaatat tttttcaatg ttgcaacacc
    26641 agagttgatc cacaataagg ttggatcgtt cacggggatc aaagacgcac taggttcaat
    26701 cgtatgtcct ttagattgga agaaatcaag aaacatttgt cgaacttgtg cactacttaa
    26761 ttgtttcatg tcattacctg ctttctataa attaaataca aaaaaacacc atcacagcca
    26821 aggacgaaaa ctcgcggtac caccttgatt gcaatgatgt gtaatcatta cctcttaaac
    26881 tcgataacgc tgagctgcgt cggtatttct accaaaatag aaaaagggag caatttgatt
    26941 agtgactatt cttttttcag ccaagaaaga attttctgtg agtcttaaaa aacaaatcat
    27001 atccttttcg tacttaatta gtatacgcat tctattgatc actgtcaata tctcaatttt
    27061 tattttcatt tccttttggt catactccac gatttttggt acgataagaa taaaggaatc
    27121 aatacatctc tgctattcat gacaaggagg aatatgatga aaaaaatagt tggagcggat
    27181 gaatggatac gcgcagctag ctgctttttg agatatcaag tttttgtatt agaacaaggg
    27241 attcctgcag aactagaatt cgacggaaaa gatatcccgc aacaaaccta ttatctattt
    27301 cttgatcaaa aaagaccagt agctactttg cgttatgaaa agaaaacacc tacttgcttc
    27361 aagccggaac gattttgcgt agcaaaagaa taccgaggaa aagggttagg cggtcagttg
    27421 cttgaagctg ctgaaaaacg ggcggtttca gaaggttgtc agactagtta tgtagtagct
    27481 gaaatgacgg ctgtagattt ttatgaaaaa caagggtatc atacttgcac agaacctttt
    27541 attgaagatg aagtactttg tatcggaatg aaaaaaagtc tagcttaaaa acaagagatt
    27601 gtgacacgcc ttttgtcaca acctcttgtt ttttatttat gtgaattttt cttattttta
    27661 cgagcagtac ggctttgctg tctgcgttcg attttgcgtt cttttttatt tttttctgca
    27721 attgcccaat cgattttttt cttataacca ggcttgatct ttttcttttt cttcttcaca
    27781 agaccaatca gcgtgggatc taatacatct tttgattttt ctcgtttggc acgtctatta
    27841 cgatcgtatg ttttgacgat ttccccgttt ttgatttctt ttggttcaaa tgagacgccc
    27901 aatttttcta tcgcatcaat ggcttgctca tcatttggcg aatataacgt aatggccgtt
    27961 ccttttaagc cattacgtcc agtacgtccg acacgatgga taaagaagtc tagatcttct
    28021 ggaatttctg cattaataac atgagagaca ccttcgatat cgatccctct agcagctaaa
    28081 tcagtcgcta caacatattg atactccaga ttctgtactt gtcgcatcac tcgttttctc
    28141 tctcttgggg tgatgtctcc atgaatcttt gctactttca agccttggtt tttcaagtaa
    28201 tcggcaattt catccacatg ctgttttgta ttggcaaata cgattgctaa ataaggatga
    28261 ccaattgtca gcagttgata aatcatttga ttctcatctt taccttttgt tgaaatcagc
    28321 caattttcaa tgtcttcaga aataactgct tttggtttga tttcttcaat gattggattt
    28381 tccatgtatt ttcgtaagaa tggacgaagt ttttctggaa tagtggcaga aaaaactaaa
    28441 aactgcagct tttctggtaa tcgacttgca atttggtcta cttcatttaa aaaacccata
    28501 tccaatgtca tatccgcttc atcgacaaca aatgcaaatg cggtgtgaat cttcagcgct
    28561 tgttcattca tcatgtctaa tattctacca ggcgtgccta ctacaacctg tggctgttgg
    28621 tgatgcagac gatttaattg acgctgtttg tctgtaccgc cgacaaaatt cgagacacgg
    28681 atctccggtg tagaaaattt agcgatttgt gtagctgctt catagatctg tgcagctagt
    28741 tccctacttg gagctgtaat aacaacttgt acttcctctt tttctgcatt gattttttca
    28801 aacaaaggca acaaaaacgt atgtgttttt cctgtaccag tttgagattg cccaatgata
    28861 ttttttcctt ttgcaattaa aggaatcaaa cgttcctgga cctctgtggg ctgtttgaag
    28921 ccctttgcgg ttaacgcttc attgataaac ggtttgaagc ggaatatatc aaaattattc
    28981 attcgtgcac ctcttctctt taaattatca cgactttggc attataacac agacaaagcg
    29041 tttttgctca gctaatttcg agaatcatca tcctttgttt ggccaatcgt gctaacagta
    29101 tatgtgtgac tagctttttc ataaaacaga atccgttttt ttctcaaaaa tgatagcaag
    29161 atatttaaaa taaaaatacc ttgtagtaac aagacaccga gagaaatgaa tactgcactc
    29221 atctgcaaca ccgtattcgt tgtcgaattc atgatttgct gaagcaactg ccccaaccag
    29281 cttaaaccat aaaaaagaaa gtacagatac ccgtagcgga tcatcaatgc ttttaaagaa
    29341 attcgttcgc ggtcttcttc caccaaacgg atacgcacaa tttttttgcc aagtgtccat
    29401 ccattggtta taaacggtac aatcataaag tataccccta cttctaataa aagccaccag
    29461 atatgagaag taactgcccc tgaatcgaac gcaattttaa agaaaatcgc cgctaccaaa
    29521 ttaataagag ataaaaatgt ccagtcgatc aaataagcga ccaagcgtcg agtcaatgag
    29581 acagtctttc ctttttcata agaaagttca tccattcgtc ttcttgtagg aagcataaat
    29641 gtaaataacg gcgtaacgac aaaaccaatg attccaccca atgtatttgt cactaaatca
    29701 ttcacatcaa ataagcggta tggtcttggg tagataaaat aaagtccact tagctgcgtc
    29761 aattcaaaaa atagagaaag gcagaaacta gcaatcatcg ttttcataaa agaaagccgg
    29821 aaataatatc ttaaataaat gccaaacggt atgagtaata aaacattaaa agctggttcc
    29881 aaaaatacac tctgcttcat tgccggcagg taggtactag gttcagacaa gaccaatacc
    29941 gtgttgtctc tgaaatgttg ccatgaagca aataaatgca gctccatctt tggccctgtc
    30001 atttgggcaa ccgtctcctt tgccggaagt ggtaagatca ccaaaaaata cgcacacaat
    30061 aaataaaaaa cgaaagaata caaaataact gcccttgtta ctagaaatgt tccatacttt
    30121 cgatattcat aaataaaaaa aacagatgag atcgctaagg ctaaaaatgg aaaaacaatc
    30181 agcgcaaaac gaatcggttc gatataactt gccatatgac tcctccttga ttctttgtat
    30241 ctctcttatc ttagcagtcc tttgctgttt caagcaagta acgaggctat tatttctcat
    30301 ttctttcaaa gtaaagtaag ataaacacaa agggggtgtc gagatgctga atatgtactt
    30361 tgtttttggc gtacctattt ttttactgtt cctttatgct acgatcgctt atgtaagaaa
    30421 aagaactaca attcattatt taggatttat tctcctgatt atttcgggtt tcatgctagt
    30481 cttcaatctt cagacttggc agcaagcact tcttgaaatg gataaaatga ctccacatgc
    30541 tttgtctaaa gtgcttggct accctgtcta tctgatttgg cttcccattt tcatttctgg
    30601 ttgcttggtt ttattaaata tttatcgcgg cgtacgccga atagttcagt tacgcaaatc
    30661 aaagtaaaag acagaaatcg gttgagcccg atttctgtct tttactttgc tatttcatcg
    30721 tagacaaaac gacatttacg tgatcaaaat taacgagtac ttttgacatt tcttccacgt
    30781 actcctcatt taaataaaat attttgtttg gcagagaagt gcagttctaa taaaattcga
    30841 atgttttagc tatctacgtt ttaaatagag ataaatcggg ataccagcaa gtgtcaatac
    30901 tatccccatc gaagctaaaa aggtctgagt gataagcgtg cttgatacga taaaagtccc
    30961 tccaatgatt gctactagtg gaataaacgg atacattgga actttgtatg gtcgaaacaa
    31021 atcaggttct tttttacgaa gaagaatgac accaacaaag accatcgtat aaaaaatcca
    31081 aatgacaaag atcagcatat ccgttagtgt atcaaaacca ccgatcatca tcatgccaat
    31141 agcgatgact agctctaaga tacctgcggc tacaggaact ttagttttat catgaagttt
    31201 agcaaagagc ttgctaaaag gcaggttgtt ttcttttgcc ataacataag ggagacgcat
    31261 tccagtaagg gtatagccat tgatggttcc ataaacagaa atcaagatac caactgtgac
    31321 cagtcttcca ccgaagccgc caaaaatcat ttttgcaacg tcacttgccg cattgctgtt
    31381 tcctgcgact ccgtcgatag atgcggttct taagaacacc gcatttacta ataaataaac
    31441 gatcatgatt ccgatgattc ctaaagaaat tgcttttggc aaatctttcg ccggcttttt
    31501 caattctccc gaaatatttc ctacgtgtat ccaaccgtcg tatgcgaaca tcgttgctag
    31561 caagcccgct cccaaggctg agaaaaatga aagattttct cctgcttgga tcggaaacag
    31621 ttggaagtct actccttctt gtcggaacaa accgaaaatg acgatcacaa acaaaggaat
    31681 aagcttgcag acaagcgtaa tcgactgaaa agcccctcca gctttagaac ctaaaaaatt
    31741 gatcaacagg atcgatacag cagctgtaac agctacggga acaatcattg actgggaaag
    31801 accaaataga ttgacgaact gtgtaccgaa aatgatcgac aaggctgcta catttgctgg
    31861 aaaataaatc acgacttgcg cccagcccaa taaaaaagct gctgtatttc cgtaaatccg
    31921 ttcgatatat ttaatcatcc ctcctgtttc tggaatagca gctgccagtt cagctcctgt
    31981 tagtcctgca cagacagaaa tcataccacc gagaaaccaa gaaaacatat gcaaactggc
    32041 ggatcctgta acttctgcta cgcttgcggc tttaaaaaat acccctgcac cgatcactgt
    32101 gcccataaca gtcgataaag cagtaaaaaa tcccatcgta cgttttaatt cattttctat
    32161 ttttacttct tttactggcg tggcttgata ttcttccatc ccttgtcccc tttcatacca
    32221 tagccaatcc caaaagtata aaaaactttt tggatgtggt tcttgtttta taccgtctct
    32281 accaattttt ctttcagttt ttccaacata tcctttgtca tcacatctaa gtcgtatttc
    32341 ggcgaaaagc cccattcctc ttgcgcacaa gaaacatcta gtgaatttgg ccaagattct
    32401 gctattgact gacgtacagg atccacatca taatccattt caaaatctgg tatgattttt
    32461 tgaatagatg ctttgatctc ttccgggtca aaagacatcg ccgatatatt gaaggcattt
    32521 cgatgaacca atcgatcagg atctgcattc atgagtttta taatggcatc gatcgcatct
    32581 ggcatataca tcatatccat tgatgtacct tgatcaatga aactagtgta ctttccttct
    32641 ttgattgctg aataataaat atcgactgcg tagtctgtcg taccgcctcc tggcaaggtt
    32701 gcataagaaa tcaatccagg gaaacggaca ccacgagtat ctacgccata tttcacataa
    32761 taataatcac atagtagttc tccagctacc ttcgttaccc catacatggt tgtaggacgc
    32821 tgaagagtat cttgtggggt atgatctttt ggagtatttg gaccaaacgc gccgattgaa
    32881 cttggcgtaa aaaatttcag ctggaattct ctagcgactt ccaatgcatt gaccagccca
    32941 gtcacgttca aattccaggc taattgtggt tttgcttctg caacagctga caaaagagca
    33001 gccaaatgaa tcaatgtgtc cacttgatat tgttctgcta tgctgcgcat tttttcgtaa
    33061 tccattacat ctaggatctc aaagatatcg tttttctcaa tgacttcagg catgcgtata
    33121 tctgtcgcaa tgacattttc actgcctagt tcttgacgta gccgtgtgat caactctgaa
    33181 ccaatttgtc ctaaacatcc tgtcaccaat acttttttca tgatgatcct ccctgatctt
    33241 ttttactact atcttcagat gattaacaat atatgcgtga acatgttctc taattttaaa
    33301 tagacgaaaa aactaaattt agttaaataa tttccatttc ttttcctatt ttttgataaa
    33361 ctgctactgc ttcatcaagc atttccctcg tatgttccgc agtcggcata tttctgatcc
    33421 tgcctgtccc aagaggcaca gttggataaa cgattggttt agcataaatc ccatgttcga
    33481 tcagcttctt agagaaagtc tgagtcactt tttcgtctcc caaaatgact ggagtaatag
    33541 gtgtttcaga cataccgatg ttatagccta cttttttcaa ttcttcttta aaataattag
    33601 cattttccca aactttttcg acaagttccg gatgttcttg catcaaagta atcgaagcca
    33661 atgcagctgc agctgcacct ggagttagcg aagtagaaaa taggaatggc cgacttctag
    33721 ctttcaacca gtcgattagt gttttcgatc cagctacata acccccaaca acacctatag
    33781 ctttcgataa cgtgcccatt tgcatatcga ttttgtcgct taatccaaaa tgcttgacgg
    33841 ttcctgcacc ttttccagtt acgcctgagc cgtgcgcatc atcgacgtag gtgatcagtc
    33901 catatttttc aacaatcgga ataatttccg gcaatcgtgc aatgtctcca tccatggaga
    33961 aaacaccatc tgtgatatac atgatttttt tatatttctt actttctatc gcttcctttg
    34021 cttttttctc aaggtctttc atatcttgat gtttaattcg gatgattttt gctccggata
    34081 agcggcaacc gtcaataata gatgcatggt ttaattcatc cgataagata gcatcttctt
    34141 ttgtcattac tgcagagata gcgcccatat tgcagttgaa tccagattga aaggcgattg
    34201 ctgcttctgt ccctttgaat tctgcgattt tttcttctaa ttgctgatgg attttcagcg
    34261 aaccattgat cgttcggact gctcctgctc ctacaccata agtttcggtt gcttcaatac
    34321 atgctttttt caattcttcg cgattggcaa atccaagata attgttggat gctagattga
    34381 tcatcttttt tccgtctacg atgatacaag caccattttc actttctagt atgtcgatcg
    34441 tattgtataa ccccttttct ttcagttgat ccaattcttt ctctaaatac attgttagtt
    34501 ctttggaaga cattgtctcc acctccatat tcatctgtct tgcagaacat accaaacata
    34561 tatcgtgtca ttcatctaca aagcaagtat gctatatttt tgataacgct tacactgatt
    34621 atgagaatta tttaaccaca ttttttattt acagtatctt tttactttca aatgacttat
    34681 atagtatgaa caattacctt ttagataatg atctatttta ctctacctgg gcagataaat
    34741 acaacacaac cattgataga agccctttcg ttaaaatcaa ttgtattctg aatatttaat
    34801 ttatttattg catagaccaa taaaaataca taaaatttcc atcttcgttt atcagcaatt
    34861 tttaatttta ctctctgaat atttcttaaa agttttactt gttgaattcg aaaaaaggac
    34921 tgtgacaaaa gtcttgtcac agtcctattc ttccgaata
//
LOCUS       DAFENC010000027        34688 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.027, whole genome shotgun sequence.
ACCESSION   DAFENC010000027
VERSION     DAFENC010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34688
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.027"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            591..1280
                     /locus_tag="LP493_001699"
     CDS             591..1280
                     /locus_tag="LP493_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2133852.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1267..2475
                     /locus_tag="LP493_001700"
     CDS             1267..2475
                     /locus_tag="LP493_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL2133853.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2769..4040
                     /gene="serS"
                     /locus_tag="LP493_001701"
     CDS             2769..4040
                     /gene="serS"
                     /locus_tag="LP493_001701"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBL2133854.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="LP493_001702"
     CDS             complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="LP493_001702"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HBL2133855.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6578..7273)
                     /locus_tag="LP493_001703"
     CDS             complement(6578..7273)
                     /locus_tag="LP493_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HBL2133856.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="LP493_001704"
     CDS             complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="LP493_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HBL2133857.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8472..8663)
                     /locus_tag="LP493_001705"
     CDS             complement(8472..8663)
                     /locus_tag="LP493_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HBL2133858.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8684..9574)
                     /locus_tag="LP493_001706"
     CDS             complement(8684..9574)
                     /locus_tag="LP493_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBL2133859.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9561..10328)
                     /locus_tag="LP493_001707"
     CDS             complement(9561..10328)
                     /locus_tag="LP493_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBL2133860.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="LP493_001708"
     CDS             complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="LP493_001708"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HBL2133861.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="LP493_001709"
     CDS             complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="LP493_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HBL2133862.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="LP493_001710"
     CDS             complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="LP493_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HBL2133863.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14899..15282
                     /locus_tag="LP493_001711"
     CDS             14899..15282
                     /locus_tag="LP493_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133864.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15450..16208)
                     /locus_tag="LP493_001712"
     CDS             complement(15450..16208)
                     /locus_tag="LP493_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HBL2133865.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16226..17044)
                     /locus_tag="LP493_001713"
     CDS             complement(16226..17044)
                     /locus_tag="LP493_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBL2133866.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="LP493_001714"
     CDS             complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="LP493_001714"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HBL2133867.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="LP493_001715"
     CDS             complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="LP493_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HBL2133868.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18173..19507
                     /gene="dnaA"
                     /locus_tag="LP493_001716"
     CDS             18173..19507
                     /gene="dnaA"
                     /locus_tag="LP493_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HBL2133869.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDIKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19705..20835
                     /gene="dnaN"
                     /locus_tag="LP493_001717"
     CDS             19705..20835
                     /gene="dnaN"
                     /locus_tag="LP493_001717"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HBL2133870.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21064..21306
                     /gene="yaaA"
                     /locus_tag="LP493_001718"
     CDS             21064..21306
                     /gene="yaaA"
                     /locus_tag="LP493_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HBL2133871.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21293..22417
                     /gene="recF"
                     /locus_tag="LP493_001719"
     CDS             21293..22417
                     /gene="recF"
                     /locus_tag="LP493_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HBL2133872.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDSRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22414..24360
                     /gene="gyrB"
                     /locus_tag="LP493_001720"
     CDS             22414..24360
                     /gene="gyrB"
                     /locus_tag="LP493_001720"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HBL2133873.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24380..26851
                     /gene="gyrA"
                     /locus_tag="LP493_001721"
     CDS             24380..26851
                     /gene="gyrA"
                     /locus_tag="LP493_001721"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HBL2133874.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27087..27386
                     /locus_tag="LP493_001722"
     CDS             27087..27386
                     /locus_tag="LP493_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HBL2133875.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27436..27948
                     /gene="ssb"
                     /locus_tag="LP493_001723"
     CDS             27436..27948
                     /gene="ssb"
                     /locus_tag="LP493_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBL2133876.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27974..28210
                     /locus_tag="LP493_001724"
     CDS             27974..28210
                     /locus_tag="LP493_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HBL2133877.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28353..30326
                     /locus_tag="LP493_001725"
     CDS             28353..30326
                     /locus_tag="LP493_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HBL2133878.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30332..30784
                     /gene="rplI"
                     /locus_tag="LP493_001726"
     CDS             30332..30784
                     /gene="rplI"
                     /locus_tag="LP493_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HBL2133879.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31058..32425
                     /gene="dnaB"
                     /locus_tag="LP493_001727"
     CDS             31058..32425
                     /gene="dnaB"
                     /locus_tag="LP493_001727"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HBL2133880.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33205..34497
                     /locus_tag="LP493_001728"
     CDS             33205..34497
                     /locus_tag="LP493_001728"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HBL2133881.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT        10563 a         6737 c         6861 g        10527 t
ORIGIN      
        1 ggagtgtttc ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagtaattgt caactctttt ttaaaagttt tttcgatttc gtttttcgaa atcttccagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcat
      241 ttccaacatg tcaacaactt attttttatt atttaataag ttattggtgt tcttttgaac
      301 aaataataat atatcaacat cacatgtgaa agtcaataag aaaatgctta tttatcaaca
      361 tttctagctt acatgatcat tggttagttc tggtcctttt tcgttcgtct ttataactcc
      421 gagagacgta aaatcctttt gttttcagtt taatgttcat gttcttgtct tattcacacc
      481 aactagatgt ctcaccttct aaaattttcc ttaacaaagt gctgctttta tctatttctg
      541 cttttttttg ctagaataat agtaacaata tgactctgga ggatttattt atgaaaattt
      601 tgattgctga cgatgataaa gaaatcgttg aattattaag tatctatgtt cacaatgagg
      661 ggtatgaagc agtaaaggct tatgatggga aagaagcatt atctaaaatc agaacaatcc
      721 ctgatattga attacttatt ttagatatca tgatgcctga gatggatggg atgcaagtag
      781 tgaaagagct acgaaaagaa tcccaaatac caatcattat gctgacagca aaaactactg
      841 atatggataa gatcaaagga ctggtcgctg gtgcagatga ttatgtgacc aagccattta
      901 atccgttaga agtaatggct agagtaaagt ctttattacg gcgtacaaaa atgcagattg
      961 ccccagatca gcctgatgta ttagaagtaa atgcattaat catcaataaa gactctcatg
     1021 aagttaaaac aatcgatggg aaagaaatcc agttaacagc tttggaattc ggtatcctct
     1081 acttgcttgc tagtcatcct aatcgagtat ttagcgcgga tgaaattttt gagcgtgttt
     1141 ggaaacaaga aagtattgtc tctgctaaaa ctgtcatggt tcacgttagt catttaagag
     1201 ataagattga agaagcaact ggtggtgaaa aagtcattca aaccgtttgg ggagtgggct
     1261 ataaaattga cgcaagatag taaacgagca actgaaaaac gccgtcggat caatttgact
     1321 tcaaaagaaa tcagcgaatt gttagcggaa ggaatcatca cgattatcct tttgcttcta
     1381 ttaaatgttt ctattctggt tgttatcagt tcggtgatca acagttcacc ttctttgacg
     1441 aatgcgattt gggattcaaa gaatattttt gcagaacgat tgaacactga tttgttctgg
     1501 aacggccgga attttattat tccctttttc tttctattag atattggtgt tttgtattgg
     1561 cgcttgattc gaagatatcg ccaaatgcaa ttgcggcata tcatcagcga acttcactac
     1621 atcgcaaacg gaaattatga tcatcgtatc ccttttgaac tgagtggtga cttaagccga
     1681 gtggtaacaa gtatcaatgg attggtggat agtaccgtag cagcgattga agacgaacgt
     1741 aaaatcgaaa aatcaaaaga tgaattgatc acgaatgtca gtcatgatat ccgtacccca
     1801 ctcacgtcca tcattggata cctaggactg atagaagatg gccagtatca ctcagaagaa
     1861 gatcttttaa agtatacgca tactgcttat atcaaagcaa agcagatgaa atctttagtg
     1921 gacgacttat ttgaatacac taaggtacgc cagcctgctg tcccggtgaa tttttctgcc
     1981 tttgacatga tccagttgat cgaacagtta gcagctgatt ttgagttgga agcttctaaa
     2041 aaaaatatcc aaatacttgt tcaatcaaaa gtagactccc ttatcatgga tggcgatacc
     2101 gaaaaacttg tacgtgtctt caataatctt ttgacgaatg cgttgaaata cggaaaagga
     2161 gcaacgaaga tcgtaatcga agtagaacgt atcggttcag aagttgttgc aacagtcaaa
     2221 aataacggag caatgatccc acaacaggca atcgataatc tattcgaccg tttttatcgt
     2281 gtagaagaat ctcgttcaca agcaactgga ggaactggac ttggtttagc aatcgctcaa
     2341 agcattgtgg ctttgcacgg cggatacatt tatgcaaaat cagataagca atggacttct
     2401 ttcatcatgc accttccaat caagaaaaat gaaaaattac ctattgatac acaggaagtt
     2461 attgacgaaa gctgaaatat tcgctattct tattacaatt attagaataa atgaaaaaca
     2521 cagaacccag tacactttat tctttttcag agagctgatg gcaggtgtaa atcagcaaag
     2581 gataatttgg aagttccagt tcgtttacgt gccctttcga aataagaaag gtcggttcaa
     2641 cagccgttat gtgttcaaca agtgcagctg acgctgaact tgggtggtac cgcgaatttc
     2701 agactgattc gtcccaagaa taatgggatg gatcagtctt tttttatttt caaaaaggag
     2761 gaaatcatat gttagatgta aaaatgatgc gacaaaatat tgaagaagta caagaaaaat
     2821 tgatgactcg gggcgtaaaa aaagaaacat tagctgaatt catggaacta gatgaaaatc
     2881 gtcgtaagct actagtcaaa agtgaagaat taaaaaaata tcgaaatgat gtttctgctg
     2941 agatcgccca attgaagcgt gcaaaagaag atgcttctgc taaaatcgct gaaatgaaag
     3001 aagtcggtgg caacatcaaa gcattggata ctgaaattgc tgaagtggat gaaaaattga
     3061 aacaaattgc aactactttg ccaaaccttc cccatgattc tgtgccagtt ggaacagatg
     3121 aagaggacaa tgtagaaatc cgtcgttgga gcgaaccacg tacatttgct tttgaaccaa
     3181 aaccacactg ggaaattgca gaaaatcttg atattttaga ttttgaacgt ggcgcaaaag
     3241 tagccggtag ccgttttgtc tattacaaag gattaggtgc tcgattagaa cgtgctgtct
     3301 acaacttcat gcttgatcag catatttacg aacacggcta tactgaaatg atcactcctt
     3361 atatcgtcaa cagtaaagcg atgtttggta cgggacaatt tccaaaattc aaagaagatg
     3421 ttttccaatt ggagaatact gatctaacat taatcccaac agctgaagta ccattaacta
     3481 actattataa tgatgaaatt ttagatggtg cagatttacc tatttatttc actgcactaa
     3541 gccctgcttt tcgttctgaa gccggaagtg ctggtcggga tacacgagga ctgattcgtc
     3601 ttcaccaatt caataaagta gaaatggtca aattttcgga tgtagagcat tcttacgaag
     3661 aattggaaaa aatgacagct gatgcagaag atatcttgaa aaaattgcat ttgccttatc
     3721 gtgtgatggc cttatcaact ggagacatgg gcttttctgc agctaaaact tatgacttag
     3781 aagtatggat acctgcacaa gatacttatc gtgaaatcag ttcttgttct aactgtgaag
     3841 atttccaagc acgccgcgca atgatccgtt atcgcgataa tgatggaaaa atccactata
     3901 ctcatactct gaatggttca ggacttgcag ttggccgtac agtagctgcc attttggaaa
     3961 actaccaaaa tgaagatggt tctgtcacag ttccagaagc gctcgttcct tatatgggga
     4021 atctgaaagt tattaaataa agaggctgtg aaaaagccgc ttagtttcga gtattaagaa
     4081 aaattttgtg aaaatggctt tccacatttt tgcataaatt ggacttaata ccgagaaact
     4141 ggcttttgaa caccatttat cgagaggttg tgaaatcagc gaattaacct gagtattaga
     4201 gaaaaaaatg gaaaaatagt ccctcatatt ttaccgtttg ttgaactaat accgagggtc
     4261 agctgattga acaccgttta gtggagaggt cgtaagccta ccccccagct cctagttaca
     4321 aggacaaatt caaaaaacag ctcttcatat tttatgaatg ttgtacttgt gattcggagg
     4381 tggcaaggga acactgttta ttcaaaaaga ggctgggaca gaagcgttta actccaagaa
     4441 ataagaagaa attcacgaaa attgcttttc aaatttttgt gaatttcttc ttatttccga
     4501 aggagttgct tctacttccg ccgtttatac gtgtttagag cgtgagacaa aagtgttctt
     4561 tacttttgtc ccacgctctt taatgttttt aagattcaac tgaatagttt ggtgcttctt
     4621 ttgtgatttg tacatcatga gggtgtgatt cttttaatcc actgccgctc atttggataa
     4681 attgcgcttc atcacgtaat tgctgtagat tggctgcccc aacataaccc attcctgaac
     4741 gcaaaccgcc gatcatttgg aaaataatat ctgcaacact tcctttataa gcaacccgac
     4801 cttcgattcc ttctggtact aatttatttg cttcattgac actaccttgg aagtaacggt
     4861 cttttgaacc tttttccatc gcgcctaatg agcccatacc tcggtatgtt ttgaatcgac
     4921 gtccttggaa gatttcgaat tcacctggtg attcatctgt ccctgccaac atacttccta
     4981 gcatcactgc atgtccgccg gcagctaatg ctttgacgat gtcaccagaa tatttgatcc
     5041 ctccgtctgc aataatcgct ttgccatatt gacgagcaac tgatgctgca tcataaatag
     5101 ctgtgagctg aggtacacct acaccggcta ccacacgtgt cgtacaaatc gatcctggtc
     5161 cgataccaac ttttacgaca tctacacctg catcatataa agcttttgtc gcttcagccg
     5221 tcgcaacgtt tcctgcaatc aatgttgcat ctgcaaaagt tgaacggatt tcttgaattt
     5281 ttcggatcac acctgcacta tgtccatgag ctgtatcgat gatgattgca tctgcccctg
     5341 cttctaataa agcattcgca cgctcaaatg tatcgcttgt tacaccaacg gctgctgcta
     5401 caagcaatcg accatgttca tcttttgctg catttggaaa ttcgatcact ttctcgatgt
     5461 ctttgatcgt gatcaatccg cttaaacgac cttcgttatc tacgattggt aatttttcga
     5521 ttttatgttt ttgcaaaatc ttttctgcat cttttagaga ggtacctact ggggcagtca
     5581 ctaagttgtc ttttgtcatc acatcagcaa tcggcatgtg ataatctgtt acaaaacgca
     5641 tgtcgcggtt tgtaattatc cctaccaatt ttctgttttc aagtgtttca acgattggca
     5701 caccactgat acgatatttg ctcatcaatt cttctgcgtc tgctacaaga tgctgcggcg
     5761 ttaagaagaa cggatcaatg attacgccac tttcagaacg tttgactttt cttacttcat
     5821 ccgcttgctg gctgatcgtc atgtttttat ggatcacacc tagtccgcct tgtcttgcca
     5881 tagcaatggc catcttgctg tcggtaacag tatccatact tgcactgatg attggaatat
     5941 tcaacttaat atttttagct aattgtacgc tcatatccac ttcgtttggt aacacgtgac
     6001 tttctgctgg tatcaataag acatcatcaa aagtaaatcc ttttttcgtg aactttgttt
     6061 cccagttgga catttttagt accactcctc taatttagtt tatctattaa aataattgat
     6121 tttttcattt aagtcaatga tctacttgga atcaagttag ctttctcata gaataccaat
     6181 ataaagcgtt tacatctgtg tgtattaaaa gagattgtaa aaaagctgtc ctgcatcaag
     6241 taataagaac agccaatcaa aaacagcttc tcatgttttt gaattggttg ggtttattac
     6301 cgcagatgca aacttttgaa caccgtttag tggagaggct gtgaaaaagc tgcttagttt
     6361 cgagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa attggactta
     6421 ataccgagaa actggctttt gaacaccgtt tatcgtaaaa agggactgtg acaagacttt
     6481 tgtcacagtc ccttactatt atttaactat ggataaacaa aatgaggttc tttactaccc
     6541 ctagatatct agcaaaatag ctgatctttt tgctagttta tcttcttggg acggataaac
     6601 ttccaataat cccgtatttt ttcttcaagt agtaacggat tgctaaagca gttgccccga
     6661 taatgataac tactactgga tctaatactg gattgataac tggtggcaat agtgttgtcg
     6721 cagaaaacag tacgacccaa agaagtgtcg ttccacctag gataagcaat gtcttaccca
     6781 ttcctggttt cttgcttcga tctgctccgg gatattcata ttgatagatg tatttgtaca
     6841 tcatataaaa gacccagcca ccgattgcag aacctagaac gagtgtagaa aagccataag
     6901 ctggcgttgt tccacgtgaa aacaatccgg taatcgcaat catgatactt aatagaccaa
     6961 gcaacagcaa cgtattatct aaccacatca ataaaggggt ggatgaattt tttacttctg
     7021 ctggcttatt gatgattgct tccgttcttt cagagactgt cccaaacaat tgacgggctg
     7081 ttcttccgcc tttttgttct gcaactaaag taggcagaat gtcatgaagg gcttttactt
     7141 tttcttcttc agacaaattc gctgcttcta aagatttttt caaatcaaaa atgtactgtt
     7201 gatttctttt ggttaatttt gtttctaaac tattgttttc ttttacgatt gctcgtaatt
     7261 gttctggttc cattatctaa tagtcctcct tagccgttcc ttttctcaac ggtcgtcaca
     7321 aaagacattc taccatattc tacagctagt ttgatagccc ttttacacat taaagcggaa
     7381 taacattacg tcgccgtctt gtacgacata atcttttcct tctaatcgaa cacgtccagc
     7441 ttcttttgct gcatgcatgt ttccgtaatg atccaagtct tcaaaagaga cagtttctgc
     7501 acggataaat ccgcgttcga aatctgaatg gatgattcct gctgcttgtg gtgctttgat
     7561 tccttttttg aatgtccaag cacgtacttc ttgttcccca gcagtaaagt aagtagctaa
     7621 gcctaacaaa tcataagcag cacggatcaa ctgatccaaa cctgattctt cgattcctaa
     7681 agcttctaaa aattccgctt tgtcttcttc atctaattct gcgatttctt cttctgcacg
     7741 agcactgacc acgatcactt ctgcattttc ttctgcagca aagttgcgca cttcttgtac
     7801 ataatgattc gcgtctgcat ctgctacgtc atcttctgag acattggcta cataaagaat
     7861 tggttttgtc gtcaataaaa atagtgattt aacgattttt tgttcttctt cagtaaattc
     7921 gatcgttcgg gcagattttc cttcttccag tacaggtttg attttatcca gtacagctag
     7981 ttctgccact gcatctttat ctttggtttt agcaactttt gctacacgag tatagcgttt
     8041 gttgatagat tctaagtctg ctaacactag ttccaagttg atcgtatcaa tatcttctag
     8101 tggatcaaca cgtccttcta cgtgagtaat attatcatca tcaaaacagc gaacaacgtg
     8161 acaaatagcg tctacttggc ggatatggct taagaattga tttcccaaac cttctccttt
     8221 acttgcgcct tttacgattc cagcaatatc tgtaaattca aaagtcgtcg gaacagtttt
     8281 tttcggatgt acaagttctg ttaagcgttg caaacgccag tcaggtactt ctaccatccc
     8341 tacgttgggg tcgatcgtcg caaagggata gtttgctgct tctgctcctg cttttgtgat
     8401 cgcattaaac aaagttgatt ttcctacgtt gggcaaccca acaattccag cagtcaatgc
     8461 cataaattta ttcactcttt ctctgcattt ttttcaatta ctttttttaa tttcttttca
     8521 aaatctcgac gggtcatcat gacgatatgt ccgcaattca tacatctgat tttgatatct
     8581 gcgcccattc gaatgacttc ccagcgattc gtctggcaag cgtgaggttt tttcatttca
     8641 acgatatcgt gcaagtcgta cataaaaata gcctcctttt tgtttattct tcatcaaatt
     8701 gaatattcaa gatatcaaga attcgagtca aatctttttg agaaagatat tcaatctcga
     8761 tcttaccttt cccatttttt tcttggatag ctacacttgt accaaattta tccatcaaac
     8821 gatcttcgct ttctcggata taatatggtt tttcctttgc tagccttggg atttttttct
     8881 tttcttttcc atcattttga tttaactcag aaacaagctg ttccagttgg cggacagtta
     8941 aattttcagt tactgcacga ttggctaatt tcaagatcaa tgttttattt tttaaaccta
     9001 acagcgtacg ggcttgtccc atagataaac gctgatcttg taccatttcc ttgacaagat
     9061 ccggtaaaga aagcaagcgc aaataattgg cgatataagg tctgctcttt cctaaacgac
     9121 tagctacttc tgcttgtgtt agtttcaggt ttttcatcag catctcatat gcttctgctt
     9181 cttctaacgg attcagatct tctcgctgca agttttccag cactgctact tgcatcatcg
     9241 cttcttcgtc aaagtctcta acgatagcag ggatcgtttc tttttcagct agtttggacg
     9301 ctcgaaaacg tcgctcccct gcaataatct catatccttt tactgcggaa cggcgtacga
     9361 tgatgggttg aaagacacct gattgttcaa tagaattagc tagttcctgc aaagatactt
     9421 cttcaaatgt tttacggggc tgatacggat ttggtcgcag ctcattcaat ggtagctgga
     9481 caacggtatc atcttttaca tccaccgtct ctaagttttc taaatcttga aacagtgcat
     9541 cgattcctcg gcctaatcct ttacttttct tcacgactta ccacttcctt tgccaatgct
     9601 tggtagactt cagctcctcg agaacgtgga tcgtagtcga tgatcggttt tccatgacta
     9661 ggtgcttctg ataaacgaat atttcttgga atgatcgttt cgtaaacttt ttcgcggaag
     9721 tatttacgta cttcttctac gacttcattt cccagatttg ttcgtgcatc atacattgtc
     9781 agtaagactc cctcgatctc taattctgga ttaaagtgtt tttggactaa acgaaccgta
     9841 ttcagtaatt ggcttaatcc ttccaatgcg taatactcac actgaacagg tatcaaaatc
     9901 gaatcacttg ctgtaaatga attgattgtc agatggccaa gagaaggcgg gcaatcgatc
     9961 aaaatataat catactgact gcttacttct gctaaagatc cttttaatct tgattctctt
    10021 gccatcattg acgtcaattc gatctctgct cctgctaatt ggagagtcgc aggcacaata
    10081 ctcaaatttt cgtgttcagt gatcaaagtt gcctcatcaa ttggcaattc attgactaga
    10141 acatcataga tgtctcttgt cacatcaggt tttctgatcc cgacaccact ggtagcattt
    10201 ccttgtgcat ccatatccac tagcaatact tttttgccaa ggctagcaag acaagcacct
    10261 agattcaccg tcgtcgttgt tttgccgacg ccaccttttt ggttcgcaac agatattatt
    10321 tgtgccatct cttctcctcc tatttgattg gctgcttatt aggcagtccg ggctttcttg
    10381 ggtatttctt tggggttggt ttcttttttt gaataacgat gatatgccgt tgatcagaga
    10441 cattcggcaa ggtaaccgcc tcttctttga ggaatttacc acctaataaa gcaatcgctt
    10501 gttttgcttc tgtcaattcc tcttcacttt ttgctgcttt caatgcataa aaatagcctt
    10561 cttgtttagc caagggcaaa cacaattccg ctaacacatt caaacgagca accgcacgag
    10621 cagtgacaag gtcaaatgat gcacgaaagt gaggattttg cccaaatgtt tctgcccggt
    10681 catgatataa ggaagcatcg attcctaata atcgggttaa ctcagataag aaggttattc
    10741 gtttattcag agaatcaacg atcgttatct gcagttctgg aaaggcaatt tttaaaggta
    10801 tgctaggaaa ccctgccccc gaaccaacat cgcataaaga taaaggttgc gtaaagtcta
    10861 cttcaaatgc taatgtaagt gaatcgtaaa aatgcttcag atatacgtct ttttcatccg
    10921 taatagctgt aaggttcatc ttttcgttcc attcgactaa tgtccgataa taaatagcga
    10981 attgattcat ttgatgatcg gtaagctcta tccctttttc tgccaaggat tggcgaaatt
    11041 cttctggtat cataaatatt cctttcattg tgaaacagca attgtttcac agattctctc
    11101 cctactttaa cgcaaaatct ctagacatgc aatccttcca tatggattct taaaaatttg
    11161 aaaagtaaga aaagccgata gactttttct ttctagtatg actcataaaa tatacacaga
    11221 agagagaact agctttgagc aatttctgca aaaactagtt ctctcttcta tttattatta
    11281 cgtattacgc tggttcactg actttcgcaa tcttcccttg ttcgatatag accattagga
    11341 tacttaggtc tgcagggttt acgccactga ttcggctagc ttgggcaatt gtttctggtt
    11401 ggattttctg caatttttgt tttgcttctg ttgctaatcc gttgattgct gcgtagtcga
    11461 tgttttctgg aatctttttc gcttccatgc gttttaattt ttctactttt tccatggctt
    11521 ttttgatgta gccttcatat ttgatttgga tttctacttg ttcgatttct tttcgtgtca
    11581 attcttcatt ttctggaata aaccgtagaa gttctgcata agtaatctca ggacgtctta
    11641 aaaagtcgct tgctagtaca ccatctttta atggtgccgc attaatcgtt gctaaaaagt
    11701 cttggacttc ttctgttggt ttgattcgta cattcatcaa acgtttgatt tcttgttcaa
    11761 ctgcttcttt tttcttcaaa taattcttgt attgatcttc ttttactaag cctacacggt
    11821 gacccatttc tgttaatcgc aaatctgcat tatcatgacg taaaagcaga cggtattcag
    11881 cacgtgaagt cagcaaacga taaggttcgt tcgttccttt tgttaccaaa tcatcgatca
    11941 tgacaccgat gtaaccgtca cttcgtttga tcactaaagg ttcttttccc tgaactttca
    12001 aagctgcatt gataccggca atcagccctt gtccagccgc ttcttcataa ccgcttgtac
    12061 catttgtttg tccagctgta taaagatttt caacgacttt agtttctaat gtcggacgga
    12121 gctggtgtgg ctctactacg tcatattcga tagcatatcc tgtacgcatc atttctactt
    12181 tttctaatcc agcaatagaa tgaagcatgt tgacttgaac atcctctggt aaagaagtag
    12241 ataaaccttg aacatagact tcttccgtat ttaagccttc tggttccaaa aataattgat
    12301 gacgtggttt gtctgcaaaa cgcacgatct tatcttcgat ggatggacaa tagcgagcgc
    12361 ctaccccttc aacgatccct gtaaacattg gggcacgatg taagttgtct cgaataattt
    12421 ggtgagtcgt ctcacctgta taggtcagcc agcaagattc ctgatctagt ttataggcac
    12481 tatctggtgt gctgaagcta aaatgattcg gctctttgtc accaggctgc tcttctgtaa
    12541 cagaatagtc gatcgtactt gattttactc gaggcggtgt tcctgttttg aaccgttcga
    12601 tagcaaagcc aagttctttt agatgattcg ctagtccaat agaaggttga gagttattcg
    12661 gacctgatga atatttcaat tcaccgataa tgatttctcc gcgaagtgct gttccggctg
    12721 taataacaac tgctttggcc cggtagctcg ctcctgtgga cgtcactact ccatgacaaa
    12781 caccatcttc gacgatcagt tcttcgacga ttccttgtct tagcgtcaaa tttggttctt
    12841 tttcgatcgt atgtttcatt tctgttgaat aagcatgttt gtctgcttgt gctcgcaatg
    12901 ctcggacagc tgggcctttt cctgtgttca acatacgcat ttggatatag gttttatcga
    12961 tattcttacc catttctccg cctaacgcat cgatttctcg aacgacaacg cctttagctg
    13021 gtccgcctac agaaggatta catggcatga atgctaccat gtccaaattt attgtcagta
    13081 ataatgtttt tgatcccata cgtgcagcag caagtgcagc ttctgaaccg gcgtgtcctg
    13141 cgccaacaac gatcacgtca tacgcatctg cttcataatg ttccaatcgt ttgttcctcc
    13201 ttttattttc ctaaacaaaa ttgactgaat aattgagtga ttagctcatc ttgtacactg
    13261 tcgccgacaa cttctcctag atagtcccag caacgcgtca tatctatttg aacgagatcc
    13321 acaggcattc ctgaatcaat acctgcaatg acttcttcaa gtgagaggga agctttttct
    13381 aacaacgcga tatggcgggt attagaaaca taagtagcgt ctctttctcc tgtttctccg
    13441 ctgaagaata aatcagaaat agctgattcc aaacgatcta gtccgtcgtt tttagctacg
    13501 gaaattgaaa aaactggttc attttcgatc aatttcttca atttttcttg ttccagctgt
    13561 gctggcaaat ctgttttatt tagaagaatg atccgtttca atccacttgt cgcttccaat
    13621 aattgttcat cttctgctgt cagtggttcg ctttggttta gaacaagtaa gatcaagtct
    13681 gcttctgcta atgcttttcg gcttctttcg accccgatcc gttccaccac atcttctgtt
    13741 tcccgaattc cagctgtatc gattagcttg agcggtaccc cccgaacatt gacatactct
    13801 tcgattacat ctcgagtcgt tcctgcaata tccgtaacga ttgctttttc ttctcttaac
    13861 aaatggttta acaaacttga tttgccgaca tttggccggc cgatgattgc cgtacttaac
    13921 ccttcccgca gaaccttccc ttgcttggat gtagcaagta gcgcttggat tctttgttgg
    13981 atcatctgcg ctttttcaag caataacttc gtagtcaatt cttcgacatc atcatattct
    14041 ggataatcaa tatttacttc tacttgtgct aatgtctcta aaatctcttg tctcaatgag
    14101 cggatcaaag cagacagatt gccgtctaac tgattaagag ctagtcccat tgctttgtct
    14161 gtttttgccc gaatcaaatc catcacagct tctgcctgtg aaaggtcaac acgaccattc
    14221 aagaatgctc gttttgtgaa ttcgcctggc tcagctaatc ttgcaccttc tcttaacaat
    14281 agctgcaaaa tttgattgac tacaacgatc ccaccgtgac aattgatttc tactacatct
    14341 tcccgcgtaa atgtctttgg tgctctcatc acggagacca tgacttcatc gacaagctga
    14401 ttgctcttgg gatcaacgat atgtccataa tggatcgtat gacttggtac ttctgataat
    14461 cgtttgtttc cagattgata aactttatct gctagttgca cagcttgatc gccacttaaa
    14521 cgaacgatac tgattgcacc ttctccaggt ggggtagaaa ttgccgcaat cgtatcaaat
    14581 tctaaagtaa tttcagccat tttttcactt cctttttcat tttgcgcaca aaaaaagtgc
    14641 ccactccacc ctttatgcac aataaacggt gaacttcgca ctttgactgc ttgttcttga
    14701 ttaaattctg gtcatagatt atcacacttg ctataaggaa tcaagtgttt aaaacaatta
    14761 gatgaagttg agcctgttct gcttccatta ccttatattt aattgtcctt ggatgtctct
    14821 ttgcgttctt tggtttattc gaagagaaga tactgtataa acaaggcttt atctttctta
    14881 aaaaaaacgg tacactaaat ggtagcgcta tctaaactat acacttttga aaggagaaaa
    14941 tatgtgagcc cgttcagatc tgctgcattg gaagaagaaa gtgaccctcg gatcaacgat
    15001 gtcgttttat ctacagggaa tatcaaccag aaatatatcg tccgcgatat cgtttttgtt
    15061 gtggaatgct tagaagctga tttgtttgac ccatcttttc ccaaagatga ccttttctta
    15121 acaacgaaga ggaaattaaa gacgaaggta cttgaatatg gtgcgaatgc agtaatcaac
    15181 tgtcattttg agtatcagca aaaaaaacgc gacggaaagt attttctgga actttttgct
    15241 tatggaacag tgatccaatt tatccaaaca acgattggtt aaatgaaaca gacaaaaaaa
    15301 gcggatcaaa actgaagaca gtttcgatcc gcttttttct atcaaagtta gtgactactt
    15361 catcgtatac tctgataaga atgatttcta gtaaaatata cttggtttga aaaactttgt
    15421 caacgtgatt tattcaaaaa gtaatggaat caataatatt ttttagcagg ttctactact
    15481 aaataacgat aaggttcctc accttccgaa tgtgttttta catgttcatc tttgcttaat
    15541 gcagcatgga tttgtttacg ttcaaatgca ggcattggtt ctaagaaaac aggctgccct
    15601 gtccgtttta ctttttcagc cgtgcgatca gctaaacgct gaatgatctc ttggcgcttt
    15661 tcacggtaat tgcctacatt gactactaca gacagcttat ttcttgctaa acgatggatg
    15721 aagacttgtg ccagatattg caatgcattc agtgtttttc catgtttccc aatcagtatg
    15781 ccttgctttt gtgtttctaa atggaaaaca accatattat ttgattctct ttccattttg
    15841 acaagagctg gagcatcaag ctgttttgaa atttcagtaa gataaactgc caattccgtt
    15901 aaagctgctt catcacctag ctcacttact tcttctgttt tttcttcaag aatcgtttcg
    15961 ttgactacct cgatctcagc tgttggttct tcttccaaaa tttcttctac agtctgttct
    16021 actgtttcag aaactttttc gctgatactt ggctggatcg aaagccgtgc attctttcga
    16081 cccattccta ggaaaccttt ttttccttct tccagtattt cgatttcgac ttggtctttg
    16141 gccaaaccca aatcagccag acctagttgg acagcttcgt ctattgttgc agcttcataa
    16201 atcggcatta gcattacctc ccctattatt tccgtttttt cttaggattc attgctttct
    16261 taagagcacg ttctctttcg cggattctcc gtgcttcttc ttcacgctct tttcgaattt
    16321 tgaaagggtt gttgatcagc agcgtttgta caacttggaa ggcattggaa actacccagt
    16381 ataatgaaag accgctggct aaattgacac ccatcactaa aatcattaca ggcatcacga
    16441 aattcatgat cttcattgat gcattcgatt caatttgact catgctagat aaatacgtac
    16501 ttgcaaaagt aaagattgct gctaaaatcg gcaaaataaa tgttggatcc gcgttcccta
    16561 agttcaacca taagaaatgc ccttgtttca actctggtac acgtgaaata gattgccata
    16621 acgccatcaa gattggcatt tgtactaata aaggaagaca accagcatat ggattgacgc
    16681 cattttctgc atataaacgc tgctgctctt ctcttaactt actttgtgtt tccggatctc
    16741 ttgaactata ttgttgctgc agtgctttta atttcggttg taattcttgc gttttacgca
    16801 tgctctttgt ttggaaatgc atcaacggca ataggatcac gcggatgatc agtgtaaata
    16861 aaatgatccc tatccctgca ttaccaaatg acaacgcctt gatcgcctca gcaaagtaat
    16921 aaacaatata acgatcccaa attcctgtac tctgtgcgct gacttcccca gttccgcaac
    16981 cggataagac gatgaccaaa ctaacgatac cggccatcaa aagtaaacgt ttgtatttct
    17041 tcacttactc ttttcctctc tgtcgattat ttttgcaagt tttaagacgt ggactaaatt
    17101 ggagcgaacc tcatcataag tcaacccctt cacacttggt ctagcaatca caataaaatc
    17161 caactccgga tcaatttctt cttttataga ataaactgct gctcggattt ttcgtttgac
    17221 ttcattgcgg tttaccgcgt tgccgacctt ttttcctaca gataaaccaa ctcgaaaatg
    17281 aggctgtccc ggtttttcca aacggtaaac gacgaatttg cggttagcaa aagaatctcc
    17341 cgtatggaac acggcttgaa actctcgttc tttttttact cgatacgctt ttctcattag
    17401 ttttctttcc ttttctatct ctcacttacg ctcataatca taccataatt acgattgtcc
    17461 tttcatcatt tccctaaaaa agagtataaa aaaaaccact gaaaccccag tggcctaagc
    17521 tgaaagaact tttcttcctt tgcgacgacg gctagctaac acacgacgtc catttttagt
    17581 actcatacgt ttacggaatc cgtgaacttt ttgacgttta cgtttatttg gttggtatgt
    17641 tcttttcata tattccacct ccaaaatgtt cttatctatt ttataaacac agacatactt
    17701 tgatagtata acgacaaagt agtgattttg tcaatataaa atagaagatc gattgttaaa
    17761 acttatccac aagattattt ttttctatgg gagtcctatg tggaaaaagt tatgcacagg
    17821 gattatccac agataataaa tggctggttt tacacagaaa acacacgtgt aaaaaaagta
    17881 atccacaatc aggtgatttc ctgtgtattc cgtctcctaa ctattggtat atctatattt
    17941 tttatccaca gatgcaagag gaaatctatt gatttttacg agttttccac ctgtgcatta
    18001 gtggtgtgga aaactttttt ttgacaactg tgtttttctc ttttttcttt ttgtcgattg
    18061 tgtggataat tgtaattaaa aaattttttt cttcggtttc tgtggaaaac tattgaaaaa
    18121 aatgctaaat tagtactagt tattcacttt ttaatgaagg aggaggcctt atatggtatc
    18181 cctcgatgct ttatggaatg aattaaaagc aacataccaa aaggatttat cgcctgctag
    18241 ctataataca tggatcgaaa cagcgaaccc tcgaaccctt gatcaaaacc agctcgttgt
    18301 tgaggttcct agcaagattc ataaagaata ttgggaaaaa aacctggcga caaaaatcgt
    18361 tgaagtcggt tatatgttat caggaaatga gattatccct cgctttatta ctggcgaaga
    18421 agcagagcaa gaagaagtta tagaagaaaa aaatccaaaa gttgtggcac ctagtccgct
    18481 aaaaaaagcc atgctgaacc ctaaatatac ctttgatacg tttgtcattg gtaaaggaaa
    18541 ccagatggct catgcagcag cgctcgttgt agcagaagat ccaggttcta tttataaccc
    18601 gctcttcttt tatggaggcg tgggacttgg taagactcac ttgatgcatg caattggtca
    18661 tcaaatgctg caaagtcagc ctaatgccaa agtaaaatat gtaagcagtg aaacttttgc
    18721 taatgatttc atcaattcga tccaaaacaa aacagcagaa gagttccgtc aagaatatcg
    18781 aaatgttgat ttactgctag tggatgacat tcaatttttt gcagaaaaag aagctacgca
    18841 agaagagttt ttccatactt tcaatgcctt gtacaatgaa gggaaacaaa tcgtactaac
    18901 cagtgatcgg ttgccaaacg agattccgaa actgcaagaa cgcctcgttt ctcgctttgc
    18961 atgggggctg tctgttgata ttacaccgcc ggatcttgaa acaagaacag cgattttacg
    19021 taaaaaagcg gcggctgaac gtctagagat cccagatgac acactaagct acatcgcagg
    19081 acaaattgat tctaacattc gtgaattaga aggtgcgctt gttcgagtgc aagcttttgc
    19141 tgcgatgaat agtgaagata tttcgactag tctagctgca gacgcactga aaacgttaaa
    19201 atcaggaaaa ggacatcctc aattgtcaat cctgcagatc caagaagaag tggcaaagta
    19261 ttatcacatc caattgaaag atatcaaagg aaagaaacgc gtcaaatcta ttgttgttcc
    19321 tagacaaatc gctatgtatt tggcacgtga gctcacagat aattctttac cgaaaatcgg
    19381 agctgaattc ggtggcaagg atcatacaac ggttatccat gctcatgaaa aaatccagca
    19441 gctgatggat tctagtgtca gtatgcaaaa tgaagtatca gaaatcaaaa actttttact
    19501 aaattaattt gtcgattcta tcaactgaaa atagcatgtg gataaaagaa aaaaacgttc
    19561 aaaagttatg cacacttttt ccacagctgt tttttcgttt ctctcttacg ttttttgagt
    19621 tttccacaga atcaacatgc cctattactt ttattattct ttttaactaa taataaataa
    19681 acaaacattc aaaggagata catcatgaaa gttactttaa accgagctag ctttatgcag
    19741 gaattgcaaa ctgttcaacg agctatttca agcaaaacca cgatccctat tttgacaggt
    19801 gtaaaaatca cactgacaca agaaggtttg actttgacgg ggagcaacgc tgatatatca
    19861 attgaaactt ttttgtctgt tgaaaacgaa aaagcaaata tgcaaatcga atctactggt
    19921 tccattgttt tacaagcacg tttctttagc gaaatcattc ggagacttcc tgaagaaaca
    19981 tttactttag aagttttaga aaataaacaa gtagcgatta cttctggaaa agcgaatttt
    20041 atcgtaaatg gattagatgc agataactat cctcatcttc ctgttgtcga aagccataac
    20101 cagatgaaat tacctgtaca cgtattgact aaactaatca acgaaacagt ttttgctgtc
    20161 tcacaacatg agagtcgtcc aatcttgaca ggtgtgcatt tcattttatc tgataattct
    20221 ttattggctg tagctactga ttctcaccgt ctaagtcaac gcgtgattcc agtagaacaa
    20281 gcggctgatc attttgatat tgttattcct ggaaaaagtt tgatcgaatt atctcgctca
    20341 ttaacaaatg aagaagaaat cgtcgaaatc agcattatgg aaaaccaagt gttgttcaaa
    20401 acagaaacga tgtatttcta ttcccgtttg ctagaaggaa actatcctga taccaatcgt
    20461 ttgattcctt caagttttaa tacagaggtt gaattttctg ttcctagctt tttagcggcg
    20521 atcgaacggg cttctttact ttctcatgaa ggccgtaaca acatcgttcg tttatctatt
    20581 cgtccagatg cggttgtttt atacggaaat tcgccagaaa tcgggaaagt agaagaaagc
    20641 ttgagttata cagcaagcag tggcgatcca ttagatattt ctttcaatcc ggattatatg
    20701 aaagcagcgt tgcgtgcatt tggagatatg agcatcaaag tgaaatttat ctctgctatt
    20761 cgtccattta cattggaacc aacggaagat ggcgttcaat ttattcagct gattactcct
    20821 gtacgtacaa attaacaatg attttcattg ttcttgaaaa tttaattgaa aagaaataga
    20881 aaaaataaaa ttttaaacag aaggccctaa aatctctttt aaggctttct gtttattttt
    20941 gtttaaatca ccttttttag attaaatcgt cttatatgga aaaatatatg gataaatttg
    21001 ttttattgcg aaaaaaaagg tataatagag tatactttta ataatgaaaa tgagggatgg
    21061 gcattgaaac aacaagtcat tctaaatacg gaattcatga cgttgggcca aatgttgaaa
    21121 gaagtcacag ttatcggtag tggcggacaa gcaaaatggt atttggcaga aaacactgtg
    21181 ttagtcgatg gcgaaccaga aaatcgtcgt ggacgcaaac tttatcccgg catgatggtt
    21241 gaagttccag aagtaggaac tttttttatg gtaaaaaaag gaaacgacga taatgaggct
    21301 gaataagctg tatttaaaaa attatcgaaa ttacgaagag ctgaacatcg aattttccaa
    21361 gaacctcgtc atctttttag gagaaaatgc gcaaggaaaa acgaatcttt tggaaagtat
    21421 ctacgtatta gctatgacgc gaagtcatcg gacaagtagt gagcaggaat tgattggctg
    21481 gactgacgat caggcgatga ttcaaggaga gatcacaaaa ggttcatcca ctcttccatt
    21541 agaaatctta ttatctaaaa aaggccgaaa aaccaagatc aaccatatcg aacaaaaaaa
    21601 gttaagtact tacgtgggac aaatgaatgt cattttattt gcaccagaag atctttcttt
    21661 agtaaaaggc agcccgcaga tcaggcggaa gtttttagat atggaattag gccagatcaa
    21721 tccaatctat ctttatgatc ttgtccaata ccaagcaatt ttgaaacaaa gaaaccagta
    21781 tttaaagcaa ttgaatgaaa aaaaacaaac tgatttgctt tatttggata ttttgtccga
    21841 acaactagca gcgtttggca gcaaagtatt gaaagcaaga gcacagttcg tcaagcgatt
    21901 ggagttttgg gctaattctt tgcatcagca aatcacccat caaaaagagc agctggaaat
    21961 cgagtatctc accgcagtcg attctttaga aacacatacg caagagcaaa tccaagaaca
    22021 atttctcgca cttttgaacc aaaataaaaa gaaagacctt tttcggggaa caacgacagt
    22081 tggtcctcat cgtgacgatc tttccttttt tattaatcag aaaaatgtgc agacttatgg
    22141 atcgcaagga cagcaaagaa caactgcact aagtgtcaaa ttagcagaaa tcgatttgat
    22201 taaagaagag acgggggaat atccaatcct tttgttagat gatgtgatga gcgagctgga
    22261 tgatagtcgt caactccatc tgctagaaac aatcgaagga aaagttcaaa cgttcttaac
    22321 aacaacgaca cttgaccatg taaaaaataa aatgactgtt gaacctgaga ttttttatgt
    22381 tcaacaaggg aaactaaaag gagaagaaac tgaatgacag aagaaagaag tttagtagaa
    22441 cgcgctaaag agtatgatgc cagtcagatt caagtacttg aaggacttga agccgttcgt
    22501 aaacgacctg gcatgtatat cggttcgact agttctgagg gtctgcatca ccttgtttgg
    22561 gaaattgtcg ataattcgat cgatgaagta ttagcaggtt ttgcaacgaa aatccatgtg
    22621 attattgaaa aagacaacag tatcaccgtt attgacgacg gtcgggggat acctgtagat
    22681 atccaggcaa aaactggacg tcctgcagtt gaaacggtct ttactgtttt acatgctgga
    22741 ggaaaattcg gcggtggtgg gtacaaagtt tctggtggac ttcacggagt aggatcttct
    22801 gttgttaacg cgctttctac acagcttgat gtcaaagtat acaaagaagg aaatgtgtac
    22861 tatcaagaat atcgtcgtgg agctgtagtg gacgacttaa agattatcga acaaacggat
    22921 cgccatggaa caacggttca ctttacgcca gaccctgaaa tttttacaga gacaactgag
    22981 tttgattttt caaaattggc tacccggatc cgtgaacttg ctttcttgaa ccgcgggatg
    23041 cgtatatcga ttgaagacaa acgagaagaa gaaccagtca tcaatgaata ccattatgac
    23101 ggcgggatta aaagttatgt cgaatacttg aatgcaaaca aaaccgtgat ttttccagaa
    23161 cctgtatatt tggaaggtga acagcaagat atcgcagttg aagtctctat gcaatataca
    23221 gacggctacc attccaatat catgagtttt gccaacaata tccatacgta tgaaggcgga
    23281 acacatgaat caggattcaa gactgcttta actcgtgtga taaatgatta tgcccgaaaa
    23341 caaaagctga tgaaagaaaa tgacgacaac ttgaccggtg aagacgtgcg agaaggattg
    23401 acagctgtta tttctatcaa gcatcctgac cctcaattcg aaggacaaac aaaaacaaaa
    23461 ttgggcaatt ccgaagtacg gacagtcact gatcggttat ttagcgaaca tttcatgaaa
    23521 ttcttgctgg aaaacccaag tgtgggccgt caaattgttg aaaaaggatt actagcttcc
    23581 agagctcgtc tagcagcgaa acgtgcgcgt gaagtaacga gacgtaaagg tgctttagag
    23641 attagtaatc tgccaggaaa attagcggac tgctctagca acgatcctga aaaatgcgaa
    23701 ttgttcatcg tcgaaggaga ttcggccggc ggatcagcta agcaaggtcg taatcgagag
    23761 tttcaagcca tcttgcctat tcgtgggaaa atcttgaatg ttgaaaaagc aagcatggac
    23821 aagatcttgg caaatgaaga gatccggtct ttatttactg ctatgggtac agggtttgga
    23881 gaagattttg atgtatcgaa agctcgctac cacaaattag ttatcatgac tgatgccgat
    23941 gtcgacggcg cgcatatccg tacattgctg ctgactcttt tttatcgtta catgcgtcct
    24001 attgttgaag ctggatacgt ctatattgct cagccacctt tatacggggt aaaacaaggg
    24061 aagaatatta cgtatgtaca accaggaaaa aatgcagaag aagagttgaa acaagtcgtt
    24121 gcttcacttc ctgcctcacc aaaaccaagc gttcagcgtt ataaaggact tggagaaatg
    24181 gatgatcatc aactatggga aacaactatg gacccaagca atcggatgat ggcccgcgtc
    24241 agtgtggacg atgctattgc agcagatcag atatttgaaa tgttgatggg ggatcgagta
    24301 gaaccccgtc gtgcattcat cgaggaaaat gcacactatg tgaagaactt agatatttaa
    24361 tcatgaagga ggaaaaagaa tgagtgaaga aatcagagaa aacatccatg atgtcaatct
    24421 aaccagcgaa atgaaagact ccttcatcga ttatgcgatg agtgttattg tcgcacgtgc
    24481 acttcctgat gtcagagatg gtctgaaacc cgttcatcgc cgtattttat acggcatgaa
    24541 cgaattaggt gtaacaccgg ataaagccca taaaaaatct gccagaatcg tcggagatgt
    24601 catgggtaaa taccatcctc atggagacta tgcgatctat gagtcaatgg tacggatggc
    24661 acagccattc agctaccgtt atatgctagt ggatggtcat ggaaactttg gttctgttga
    24721 cggtgacggt gccgccgcta tgcgttatac cgaagcacgg atgagcaaaa tcgctacaga
    24781 aatgctgcgt gatatcaata agaacactgt tgatttccaa agcaactatg atgatacaga
    24841 aaaagaacca gttgtactac ctgctcgctt cccgaatctt ttagtgaacg gaacaacggg
    24901 gatcgccgta ggtatggcca cgaatatccc acctcataac ttgtctgagg tagtagcggc
    24961 tatcgatttg ctgatggata atcctgatgt gacgaccaat gaattgatgg aagtattacc
    25021 tggaccagat tttccaacag gtggtttggt tatgggaaaa tcaggaatcc gaagagcgta
    25081 tgaaacaggt aagggttcta ttaccgtacg tgcaaaagtt gagattactg agatgccaaa
    25141 tggtaaagaa cggatcatcg tgacagaatt gccttatatg gtcaataaag caaaattgat
    25201 cgaacggatt tctgaactgc acagagacaa gcgtatcgaa gggatcacag atttgcggga
    25261 cgaatcttcc cgtgaaggta tgcggatcgt cattgacatc cgtcgtgacg ccagcgcatc
    25321 tgttatcttg aataacttat ataaattgac atccttgcaa aattcatttg gattcaatat
    25381 gttggcgatc gaaaaaggtg tgccgaaagt tttgagcttg aaacaaattc ttgaaaacta
    25441 tatcgaacat cagcgcgaag tcatcacaag acggacagtc tttgaaaaag aaaaagcaga
    25501 agcaagggca cacattttag aaggtttgcg tattgctttg gatcatatcg atgaaatcat
    25561 tgcgattatc cgcgggtcta aatcagatga cgaagcaaaa gcgacgatga tcgaacggtt
    25621 cgatttatcc gatcgccagt ctcaagctat tttagatatg cgtttacgcc gattgaccgg
    25681 tttggaacgg gaaaaaatcg aaaatgaata ccaagaactc ttaaaactga ttgaagattt
    25741 aactgacatt ctggcaagac cagaacgtgt tacagaaatc atcaagaatg aattagcaga
    25801 cttgaatcaa cgatttggtg ataaacgacg cacagaatta ctagtcggtg aggtcttaag
    25861 tctggaagat gaagatttaa tcgaagaaga agaaatcgtt attacattga caaacaatgg
    25921 ttacatcaaa cgtttggcaa ataatgaatt cagagctcaa cgaaggggtg gacgtggtgt
    25981 ccaaggaatg ggtatccaca atgacgactt cgtcaaaaat ctggtttctt gttctaccca
    26041 tgatacattg ttattcttta cgaataacgg aaaagtgtat cgggcaaaag gatacgaaat
    26101 tccagaatac gggcgcacag ccaaaggaat accaattatc aatttactag gtatcgattc
    26161 gagtgaaagc atccaggcaa tcattgcggt gacgggagaa gcagaagaag gccactatct
    26221 cttctttacg acgcgtcaag gtacagtaaa acgtacttct gtcactgctt ttgctaacat
    26281 ccgaagtaat ggtctgatcg caattggttt gaaagaagac gatgagctcg tcaatgtgct
    26341 actgacagat ggtcaatcta atatcattat tggaacacat aacggctact ctgtcacttt
    26401 caaagaagaa gcagtccgcg atatgggacg tacagcttcc ggggttagag gaatacgcct
    26461 gcgtgaggaa gattatgtcg ttggggcagc cttaatgaag gaagatcaag aagtattagt
    26521 gatcacagaa aaaggttacg gaaaacggac aaaagtatcg gaatatccag tgaaaggccg
    26581 cggaggtaaa gggatcaaaa cggcgaacat cactgaaaaa aatggtccac tagctggatt
    26641 gaccactgtt tctggagatg aagacatcat gctgattaca gataaaggtg tcattatccg
    26701 tttcaacgta tcgactgttt ctcaaactgg acgttcaaca ttaggcgtac gtttgatgaa
    26761 gatggaagct gatacgaaag ttgtcacgat ggcagcagtc gaaccagaag ctgcagaaca
    26821 aacagttgaa gaacaaggat cagaagaata gccatcaaga ctaattgtgt aagctagcaa
    26881 gaatgaccga ttaaaaaatc tggttattcc tgctggcttt tttgattagt tgaatttctc
    26941 ttaaaatatt cgaaactgtt cattctgtat tgcttttgac caaaatagag tgtataatca
    27001 gagcttgtga gtagtctaat taattagata actctccttg ctcttaggaa cctaagagcc
    27061 gaaagtccac agggaggtga atatcaatgg aaaacacgaa atatgaaatc atgtacatta
    27121 ttcgtccaaa cattgatgaa gaagcaaaaa ctgctttaat cgaacgtttc gatgcaatct
    27181 tgaaagataa cggagcagaa gttatcgaat caaaagattg ggaaaaacgc cgtttcgctt
    27241 atgaaatgaa cggttaccgt gaaggtatct atcacatcgt taaagtatct tctccatcat
    27301 cagcaaatgc tgtcaatgaa tttgaccgtc ttgctaaaat caacgacgat atcattcgtc
    27361 acatgattgt taaagaagaa gcttaattgt tgtttcatgt gaaacaatag aaaacgatga
    27421 gaggagatga ctattttgat taataatgtt gtattagttg gacgtctgac gaaagatcca
    27481 gatttgcgtt acacagcaag tggtacggca gtcgcaacat ttactttggc tgtgaatcgt
    27541 aattttacaa accaaagcgg caatcgcgag gctgatttta tcaactgtgt gatttggcgc
    27601 aaatcagcag aaactttagc aaactatgct cgtaaaggaa cacttttagg tgttactgga
    27661 cgtatccaaa ctcgttctta tgataatcag caaggacaac gtgtatacgt gacagaagta
    27721 gtagctgaca acttccaatt gctggaaagt cgttctgcat ctgaaaatcg ccaacaaagc
    27781 ggcggattcc aaagttctgg tcaatcagct ggcggatttg gcggaaacaa taactctaat
    27841 caaacatctc aatcatccaa cggtatgcct gatttcgacc gtgatacttc tgacccattc
    27901 ggctcaagtt caacgatcga catttcagac gatgatttac cattctaaac gaatttgata
    27961 ggagggaaat agaatggcac aacaaagaag aggcggacgt aaacgtcgta aagtagacta
    28021 cattgctgct aaccatattg aatatatcga ttataaagat atcgaattac taaaaagatt
    28081 tatttcagaa cgcggtaaaa tcttgccacg tcgtgtaact ggtacaggcg ctaaaaacca
    28141 acgtaaaatt actgttgcaa tcaaacgcgc tcgtatcatg ggcttgctac ctttcgttag
    28201 cgaagactaa taaatcctag gaattgaatg actgatcctt ttgatcagct attcaattcc
    28261 tttttttctg taaaaataac ctctattcgt ttagtcgctc gaatgacgaa agttatggta
    28321 aaatcaaatt agtcatatat gggaggaaaa ttatggaaaa taaaaacaat catttatccc
    28381 cgaaacctct cttccttatc ctgtttatat taatcgaagt attggtagtc ttaattttac
    28441 catttcgttt tgttagcgct tcggtcattc tattgatgaa tttatggggt gttcgctatt
    28501 ggttgaaaat gaaacgttgg cttattttaa ataaacgtga aaaaatccag caggcttcga
    28561 ctgtagctga aaccaatcta gcttatgtct cagaagtcat gcctgtagga gtgattgctt
    28621 atcagccatc aagccaaaaa atcgaatggc tcaatccatt agcattgaaa atcaaagatc
    28681 aaagtggatt aacagaggaa gaattgctag atactttttt tactgcaaaa gaaaaaaaga
    28741 aaaaccaagt ctatctagca gataaaacat ttcagtttga tatggataca gtaaagggtg
    28801 ttgtttattt taatgatatt acccaaaacc agttgttaaa actccatcag acgaacagtc
    28861 agccggtgat tggtatttta tctattgata actatgcaga tgccattgat aaattggatg
    28921 acaaagagat ttcttatttg aactctttcg tcactacact agtttctgac tggatgaatg
    28981 aataccatgt ctttttcaaa agaatcaacg cagaacggtt tttcttcgta gcacagatga
    29041 tcgatctgaa aaagatgatg gataaaaaat ttgatttgct ggatcgcttt cgagcagaag
    29101 ctgaaaaaca gagctcgcct atcaccctta gtatggggat tgcttatggc tcaagaaccc
    29161 tcgatgaaat cggtggagaa gctcagaata atttagatgt tgctttagtc cgtggaggcg
    29221 accaagttgt cgtgaaagag gtaaaagaag gagcaaaacc tgtttattat ggggggaaat
    29281 ctgctaagaa tgtcaaacgc acgcgtgttc gttctcgagc gatgagtacc gctttgcgtc
    29341 ggatttttga tgaaacaggc gatgtgttta tcatggggca caagtttccg gatatggatg
    29401 ctttaggctc tgcttttggt gtcagttgtc tggcacgctt caaccagaaa aaagcttaca
    29461 tcgttatcaa cgagaacgag atcattccag atgtagaacg gtgtcttgaa gaaatccata
    29521 agcatcctga attagaaatg caactaatct ctccagaacg tgccatagag ctgaaaaaag
    29581 aagaggacct cctcgtgatg gtggattacc ataaaccttc tctatcgatc tctcagggcc
    29641 tatatgagca atttgataag attgtgatca ttgatcacca tcgtcgtggg gaagagtttc
    29701 caagtaaacc tctgctgact tatatcgaat cttcagcttc ttcagcttca gagctagttt
    29761 ctgagctgat ccaataccaa agcagcaaaa caaatcgctt agatcgtttt gaggccacat
    29821 tattgcttgc agggatggtt gtagatacaa atagtttcaa tgtccgtaca actgcacgaa
    29881 cttttgacgt tgccagctat ttaaggtctt gtggagcaga cgcatcctta gtacaatatt
    29941 tattgagctc ggatttagcg acatacttgg agatcagcaa tttgattgct ggaagcgact
    30001 atgtgacttc tgatattgtt gtggcggcag ggacagacga aaaagagtat aatagtgtta
    30061 tagcagcaaa aacagcagat acattgcttt cgatgatcaa tatcaatgca gctttcgtca
    30121 ttacaaagcg gacagacggc ttgattggga tcagtgccag aagtaccggc acgatcaacg
    30181 tccaaatcat catggaatcc ttaggtggcg gaggacactt cacaaacgca gctactcaac
    30241 tggaaaatac gacagttgag gaaacaaaac agaagctatt tgctgcaatc aaagaaaata
    30301 tgaatcaaat atatgataag gagtaatcca aatgaaagta atttttttac aagatgtaaa
    30361 aggaaaaggt aaaaaagggg acatcaaaga agttccagca ggttatgcac aaaattatct
    30421 aatcaaaaat aacttggcaa aagaagcaac gaaaagcagt atcagtcagt tagcaggaca
    30481 aaagaaagca caagaaaaac acgaagctga aatcttggaa gaagctaaaa agttaaaaga
    30541 attcttggaa aaagaagata ctgtagtcga attgaaggcg aaagcagggg aagacagccg
    30601 tttgtttggt tcgatccctt caaaacaaat tgctgaaggg ttaaacaaac aatacaaaat
    30661 caaattagat aaacgaaaaa tcgaattaga aaatccgatc cgttcactag gctacacaaa
    30721 cgtacctgtt aagcttcatc atgaggtgac ggctacgatc aaagttcatg tcgtacaaga
    30781 ataacaaatc ttgatagcga tgttcagctg gtaagtataa ccagaaggaa aaaagacaaa
    30841 ccgaaattta tctgagaaaa cagctgcagc aatgaaagca aaagctgcaa atcgatttca
    30901 gattgatttc ggtttctttt ttgggaacag caaaatagca taaagaaaac gagtataata
    30961 aaagagaact atttttttat tacactttcg gtacgaatga tgacttttct ctcattttct
    31021 tgtaaaatga agcaattgaa gacaaggagc gatacgtatg aatgaagtgt ggcaggatcg
    31081 aatcccaccg caaaatattg aagctgaaca agcggtttta ggctctgttt ttcttgacgc
    31141 agaaacgatc attgatgcca tggagtacat agagccaaaa gacttttatc gtcgtggcca
    31201 tcaaattatt tttgagacaa tgatcgagtt aaatgatcgt aatgaagcga ttgacgtggt
    31261 tactgtcaaa gaccggctgg aacaagccaa tttgttagaa gatgccggtg gtttaagtta
    31321 tctctcagac ttggcattag cagttccgac agcagcaaat atcgtctact atgcgaaaat
    31381 cgttgaagaa aaatcattgc tgcgtacatt gatccagaca gcaacaggaa tcgttacgaa
    31441 aggattcgag caaggagaag aagttcaaac aattttagat gatgccgaac gcagtatctt
    31501 ggaggtttcg gaaaaaagaa atcgaagcgg ctttttatct attgctgaag tactgaactc
    31561 cacgattgaa aatatcgatc gactagctca aaacaatgaa gaaatcacag gtctaccaac
    31621 tggctatcaa ggtctggata aaatgacagc aggtttccag cccgaagaac taatcattct
    31681 tgctgcacgt ccagcggtag gtaaaacagc gtttgcattg aatattgctc aaaatgtagg
    31741 aacaaaaaca gatcgttctg ttgcgatatt tagtttggaa atgggggcag aatctcttgt
    31801 aaatcggatg ctttgtgcag aaggttcgat tgaggccagc catttacgta caggtcagct
    31861 ttcggaagaa gaatggtcga atctgatcgt tgcgatgggg agtctttctc gagcaaatat
    31921 ttttatcgat gatacaccag ggatcaaaat ctctgaaatc cgtgcgaaat gtcggaaact
    31981 agcgcaagaa aaaggcaatc taggcttgat attgatcgat tatttgcagt tgattgaagg
    32041 taacggtaaa gagaaccgtc aacaagaagt atcagatatc tctcgccaac tgaaaaaact
    32101 ggcgaaagag ctgaaagtac ctgtcattgc tctttcacag ttatctcgtg gagtagaaca
    32161 gcgacaagac aaacgaccag tgctaagtga tattcgtgaa tccggatcaa ttgaacaaga
    32221 tgcggacatc gtagccttct tgtatcgaga tgattattat gaaagagaag gcggagatga
    32281 cgatgatgga aacgagccaa aaaatgacaa cgtcatcgaa gtcatcatcg agaagaaccg
    32341 aagcggtgca cgaggaacag ttgaactact gtttatcaaa gaatacaata agttttcgtc
    32401 gctttcgcca agagaagaat tttaaagaag aggttgtgag ccttgagcaa tcccgagagc
    32461 tctcgtaaga agatgcaagg agtaaccgca ggaacgacta gagtacttaa tttaaacaga
    32521 tctccaaagg gattgtgaca aaagtcttgt cacagtccct ttttccgaat aaacggtgtt
    32581 caatcagctg acccttggta ttagctcagc aaacgtcaaa atatgaggaa ctattttgac
    32641 gtttgtttct ctaatactca ggtcaaaacg ctgatcttac gacctctttt ccttaaacgg
    32701 tgttctcctg ccaactcctc ggtcacaagt cacaatatca tcaaacatga gaagcagttt
    32761 tttgaaattg ctccttgtga ctcagagtta aacggcaggc tcacaacctc tttcttaaac
    32821 ggtgttcaaa agcttgcatc tgcggtaata cgcccaatca aacgaaaaat atgagaagct
    32881 atttttgttt ggctgttctt attacttgat gcaggacagc tttttcacaa cctctgattc
    32941 acggtgttcc aaaagtagct tcttcgaaaa ataagtcgaa atttcacaaa aatttgagaa
    33001 gcaattttcg tacattcctt cttatttctt gaagctgacc acttctgtta caacctcttt
    33061 tttaataacc attctaaaaa gataaagttc gttttttaag cgtttttata aaataaaaat
    33121 aaaaatcatt cgattttatt tgaaatatgt atctattatt gatacaatgg ttcaggatta
    33181 aataatatag aacgaggtgt tcacatgtca tctgtagtag tagtaggtac gcaatggggc
    33241 gatgaaggga aaggaaaaat cacagacttt ctcagtgaaa atgctgaagt gattgcacgg
    33301 taccaaggtg gcgacaatgc agggcacaca attaagttta acggtgtgac ttataaactg
    33361 catttgattc cttctgggat tttttataaa gacaagatca gtgtgatcgg aaacggcgtt
    33421 gtagtcaatc ctaaatcatt ggttaaagaa ttagcttatt tacatgaaaa aggtgtagaa
    33481 acaagtaatt tgcgtatttc tgaccgcgcg cacgtaatct tgccttatca tatcaaattg
    33541 gaccaattac aagaagatgc taagggcgaa aataagattg gtacaacgat taaaggaatc
    33601 ggacctgcct atatggataa agcagctcgt gtaggtatcc gtattgcaga cttattagat
    33661 aaagaaattt ttgaagaacg tcttcgtttg aatctagatg acaaaaaccg tcaatttgta
    33721 aaaatgtttg attcagaacc acttgatttt gacgatattt ttgaagaata ttatgaatac
    33781 ggacaacaaa tcaaacaata cgtcacagat acttccgtta tcttgaatga tgctttggat
    33841 gcaggcaaac gcgtgttgtt tgaaggcgca caaggtgtaa tgctggatat cgaccaggga
    33901 acttatcctt ttgttacttc ttctaaccca gtagccggtg gggtaacaat cggaagcggt
    33961 gtagggcctt caaaaatcaa taaagttgtc ggcgtctgca aagcctatac gtcacgtgtc
    34021 ggtgatggac catttccaac tgaattattt gatgaaacag gagaacaaat ccgcgaagta
    34081 ggacgagaat acggtacgac aactggtcgt ccgcgtcgtg taggctggtt tgattctgta
    34141 gttatgcgcc attctaaacg agtttcaggt attaccaacc tatctttaaa ctcgatcgat
    34201 gtattaagtg gattggaaac agtaaaaatt tgtacggctt atgaattaga tggcgaacta
    34261 atctaccact atccagcaag cttgaaagag ttgaaccgct gcaaaccaat ctatgaagaa
    34321 ttgccaggct ggtcagaaga cattacagga tgcaaaacac ttgcagaact gccagaaaac
    34381 gcacgtaact atgtacgtcg tatctcagag cttgttggtg tacgtatctc aacattttct
    34441 gtcggacctg atagaacaca aacaaacatc ttagaaagcg tctgggcgca aatctaagga
    34501 taaaaacgac gactgaatca ggacgttctt accagagcga gtcgaagtgt ttatctatac
    34561 gataataata acttgaagag gtagtgaaag agacgtttag ccttattgcc gataggctgt
    34621 ctcttgaaca ctgtttattc agaataaggg actgtgacaa aaaccgtgtc acagtccctt
    34681 tttccgaa
//
LOCUS       DAFENC010000028        34662 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.028, whole genome shotgun sequence.
ACCESSION   DAFENC010000028
VERSION     DAFENC010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34662
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.028"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(313..2205)
                     /locus_tag="LP493_001729"
     CDS             complement(313..2205)
                     /locus_tag="LP493_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2133882.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(2202..3929)
                     /locus_tag="LP493_001730"
     CDS             complement(2202..3929)
                     /locus_tag="LP493_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2133883.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(3945..4595)
                     /locus_tag="LP493_001731"
     CDS             complement(3945..4595)
                     /locus_tag="LP493_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBL2133884.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            4799..5095
                     /locus_tag="LP493_001732"
     CDS             4799..5095
                     /locus_tag="LP493_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBL2133885.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            5287..5907
                     /locus_tag="LP493_001733"
     CDS             5287..5907
                     /locus_tag="LP493_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HBL2133886.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(5999..7165)
                     /locus_tag="LP493_001734"
     CDS             complement(5999..7165)
                     /locus_tag="LP493_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL2133887.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(7177..7530)
                     /locus_tag="LP493_001735"
     CDS             complement(7177..7530)
                     /locus_tag="LP493_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBL2133888.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            7658..8680
                     /locus_tag="LP493_001736"
     CDS             7658..8680
                     /locus_tag="LP493_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HBL2133889.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            8699..8860
                     /locus_tag="LP493_001737"
     CDS             8699..8860
                     /locus_tag="LP493_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133890.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(9119..9553)
                     /locus_tag="LP493_001738"
     CDS             complement(9119..9553)
                     /locus_tag="LP493_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133891.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMDIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(9663..11522)
                     /locus_tag="LP493_001739"
     CDS             complement(9663..11522)
                     /locus_tag="LP493_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBL2133892.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(11640..12800)
                     /locus_tag="LP493_001740"
     CDS             complement(11640..12800)
                     /locus_tag="LP493_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HBL2133893.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(13107..14531)
                     /gene="araA"
                     /locus_tag="LP493_001741"
     CDS             complement(13107..14531)
                     /gene="araA"
                     /locus_tag="LP493_001741"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HBL2133894.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(14547..15245)
                     /locus_tag="LP493_001742"
     CDS             complement(14547..15245)
                     /locus_tag="LP493_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBL2133895.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(15202..16863)
                     /locus_tag="LP493_001743"
     CDS             complement(15202..16863)
                     /locus_tag="LP493_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HBL2133896.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            17081..18481
                     /locus_tag="LP493_001744"
     CDS             17081..18481
                     /locus_tag="LP493_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HBL2133897.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(18733..19812)
                     /locus_tag="LP493_001745"
     CDS             complement(18733..19812)
                     /locus_tag="LP493_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2133898.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(19898..20857)
                     /locus_tag="LP493_001746"
     CDS             complement(19898..20857)
                     /locus_tag="LP493_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBL2133899.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(20869..22380)
                     /locus_tag="LP493_001747"
     CDS             complement(20869..22380)
                     /locus_tag="LP493_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBL2133900.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(22402..22966)
                     /locus_tag="LP493_001748"
                     /pseudo
     CDS             complement(22402..22966)
                     /locus_tag="LP493_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
     gene            complement(22972..23835)
                     /locus_tag="LP493_001749"
     CDS             complement(22972..23835)
                     /locus_tag="LP493_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL2133901.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(23849..24745)
                     /locus_tag="LP493_001750"
     CDS             complement(23849..24745)
                     /locus_tag="LP493_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBL2133902.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(24920..26209)
                     /locus_tag="LP493_001751"
     CDS             complement(24920..26209)
                     /locus_tag="LP493_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBL2133903.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(26181..27698)
                     /locus_tag="LP493_001752"
     CDS             complement(26181..27698)
                     /locus_tag="LP493_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBL2133904.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            27896..28786
                     /locus_tag="LP493_001753"
     CDS             27896..28786
                     /locus_tag="LP493_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HBL2133905.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(28859..29683)
                     /gene="nadE"
                     /locus_tag="LP493_001754"
     CDS             complement(28859..29683)
                     /gene="nadE"
                     /locus_tag="LP493_001754"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HBL2133906.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(29695..31167)
                     /locus_tag="LP493_001755"
     CDS             complement(29695..31167)
                     /locus_tag="LP493_001755"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HBL2133907.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(31804..32166)
                     /locus_tag="LP493_001756"
     CDS             complement(31804..32166)
                     /locus_tag="LP493_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBL2133908.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            32389..33141
                     /locus_tag="LP493_001757"
     CDS             32389..33141
                     /locus_tag="LP493_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBL2133909.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(33281..34204)
                     /locus_tag="LP493_001758"
     CDS             complement(33281..34204)
                     /locus_tag="LP493_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2133910.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(34219..34491)
                     /locus_tag="LP493_001759"
     CDS             complement(34219..34491)
                     /locus_tag="LP493_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133911.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        10231 a         7212 c         5979 g        11240 t
ORIGIN      
        1 caagaggttg tgagcctgcc gtttaactcc gagtcacaag gagcaatttc aaaaaacagc
       61 ttctcaggtt tgttgactat tgtgacttgt gaccgaggag ttggcaggag aacaccgttt
      121 aaggaagagg ttgtaaaatc agcggtttga cctgagtatt agagatacaa aacggaaaaa
      181 tagcttctca tattttgccg ttttttgagc taataccgaa ggacagctga ttgaacaccg
      241 tttattcgga aaaagggact gtgacacgac ttttgtcaca gcccctaaaa aaaataataa
      301 atttgtacta ttctatgaag cttcttcttc agaaaactga ctgttataaa gatctgcata
      361 gaatccgtct ttttccatca atgtatcgtg gtttcctgtt tctacgatcg aaccatgatt
      421 catcacaata atgttgtctg catcgcgtat tgtagacaag cggtgagcaa caacgaaact
      481 tgtccggttt tccaataggc ggttcatcgc tttttgaatc agtatttctg ttcgtgtatc
      541 tacactagat gttgcttcat caaggatcag gacatctgga tttgctaaga atgcccgcgc
      601 aattgtgatt agctgacgct gcccttgcga aatattgctt gcatcctcgt ttaatacagt
      661 gttatatcct tctggcaatt tacgaacaaa atcgtctacg tgagcagctt tagcagcctc
      721 aatgatttgt tcgtctgttg catcgtcgtt cccatatttg atattgtcat agatacttcc
      781 tgtaaacagc caagtatctt gcagtaccat tgaaaactgt gcgcgcaatt catcacgtga
      841 aagatcacgg gtatctacac catcgtaacg aatactacct ccagaaacat cgtagaaccg
      901 ttcaagaagg ttgatcagtg tcgtcttccc tgcaccagtc ggacctacaa tagcgaccat
      961 ctcaccaggt ttgacatcca agttaaaatc agtcattagc aagttatctg gtgtgtagcc
     1021 gaattgaaca ttttcaaaac gaactttgta tggtgtatct ttttcttctg gaaggccaga
     1081 tttttcattg gacatctctt cttcatccaa cacttcaaat acccgttcgg ctgaagcaac
     1141 tgttgattgg atagtgttca tcaaacttgc aagttgagtg attggttgag agaactgtgt
     1201 tgtatattgc aagaacgctt gaacatcccc taatgtcatg ttcccatttg caacttttac
     1261 tccgcctagt acagcgacga acacatagcc tagattttta acgaaattca tcaacggcat
     1321 gatgattgcc gaaataaatt gagctttcca accagcggca tacagattct gattttcttt
     1381 ttcaaatact tcctggtctt tttcagtatg attgaatgtt ttaacaatgg tatgaccacc
     1441 atatgtttct tctacttggt tattcaataa acctaaactt ttttgctgat ctgcgaaaaa
     1501 cacttgtgat ttcggcgcta cgatcatcac gatgatcaag cttaaaggga tcatcaataa
     1561 cgcgactaac gtcaattgcc agctgattga aagcatcatc acgatgaccc caatcaatgt
     1621 gactgcacta gttacaaatt gagtcaaatt ttgctgcagc gtgcttgcga tgttatccat
     1681 atcattgatt gctcgagaca tgatatcccc atttgtatgt gtatcataat aggaaatcgg
     1741 tacacgattc attttggctt ccaaatcatg acgtaattca taaactgttc gttgggaaac
     1801 acgtgtcata ataaattgct gtaaaaagtt gaatacagca gaaatcaaat acatcacgat
     1861 tactgtcgca atgatctgcg cgattttatc aaagtctatc ggaaattttg ttacttgttg
     1921 gccttgttgc atctgttgag cgccagccat tacacctttg aatatttctg tggttgcttt
     1981 ccccaagacc tttggtgttt ggatttggaa gatcacggct gctattgcta gtacaaatac
     2041 agcgatgatc gcaaccatac gtttagacat atagccaaac aatcggcgta ccgttcccca
     2101 gaaattttta ggcttttcac cttttacacc gagatttctg ccaggtccac catgtcctgg
     2161 accgcctgct ggtccatgag agggacgtgt gtttgtttta ctcatgctaa gtcctcctct
     2221 cttagttgtg aatgaacgat ttcttgataa gtttcgtttg ttgctaatag ttcttcatgt
     2281 gttcctttgc caaccagttt tccttcatct agcacaagga tcatatctgc atccattact
     2341 gtacttactc gttgagcaac taaaacggtg atactttctt tcatattcgt tttcaatgct
     2401 tggcgaagat tggcatccgt tttgaaatcc aacgctgaga aggaatcatc aaacacatag
     2461 atatctgctg ttttgactaa tgcccgtgca attgccagac gctgtctttg tccaccagag
     2521 aagtttcctc ctccttgttc cacatggcta tctaagccat cttccatctc tgaaacaaaa
     2581 tctttagctt gtgcgatttc taatgctttc caaatcattt catctgttgc atccggctta
     2641 ccatactgca tattgtctcg gatcgttcca gagaacagaa ctgctttttg aggaacaaag
     2701 cccattaatt ctcgcaaatt atattgagtc atgtcactaa tgtccgttcc atttatttgg
     2761 atcgaaccag attcgatgtc atataatcga gggatcaaat tgactaaggt cgttttacct
     2821 gaaccagtcc cccctatgat tgcgacgatc tcgcccgact tggcttggaa atcaatatct
     2881 tccaatgcaa gtttttctgc tccatgatat cgataattga catgattgaa ggccaatgtt
     2941 gcgttttttc cagcaaaaga aactgtttta ggattttcag ggtcatggat accgattttt
     3001 tcatccaaca cttcattaat acggtcagct gaagcttgtg cacgaggcac catgataaaa
     3061 atagcggaaa gcatcataaa gctgatcaag atctgcatcg cataagtcat aaatgcaatc
     3121 agattaccga cttccaaagt catatctgct atgtagtgtc caccaaacca agtgattgct
     3181 acgtttgtac cgctcatgat caatgtcatc attggcatca tcaatgcgac gatcgtatta
     3241 actttgattg ccgtatttgt ataatcttta ttcgctaaat caaaacgatt ttcttcaaag
     3301 cgtgtcttat cgaatgctcg aatcactctg acccctgtca atccttctcg aaataccagg
     3361 tttaaacggt cagttttctt ttgcatactt ttgaataatg gaacagcaaa gtacatgatt
     3421 ccgccgatca aaataatcat tactgggatg acaactaaga agatttttgt caactgatga
     3481 tctttttgat aagcaagtat gctcgcgcca atcaacgtga ttggtgcatt gatcatcata
     3541 cgtaaaaaca tttgtgtaac catttggatt tgagtcacat cattggtcgt tcttgtgatc
     3601 aaagaggccg ttccatattt atcaaacgca tcttttgtca gactctctga ttttttatag
     3661 acatccgtac gcaattgctt acccagtttc tgtgattcac gagtagcaaa aaatgtattt
     3721 gcgatagcag ctaagatact gatcaaagaa aagccgatca tcacaaaacc tgtatgccaa
     3781 atataatcga catctccttg cgctacccct ttatcaataa tattggaggt aagtgtcggc
     3841 aaatataaat ctgccagtac ttggatcacc atgaaaactg cagctgcaat tgctgaagtc
     3901 aaggagatcc gttttacgat ttttagcatc tagttccctt ctttctattt atatactccg
     3961 tttttcagcc aagaaagttt caaattgaat tcactgattg cttgctctac tgagtaatct
     4021 tcagatgttg aaaataagcg atacgaatgc gcaattgttg taaatacagt attcatcact
     4081 aattggatca gtaattccaa ttcatgatca ttttttactt tcagcttcgt ccgatcgatc
     4141 aattcaagca actcttttgc atcttgtttg tgttctttat gtggatcgtg aggcgttttt
     4201 tggcgactcg tatgaggagc gacttttctt gaggcacggt aatccatgtt cataaacaag
     4261 ttacgataaa aagaagcatt ctcgccttcc aaaatctcat aaatcatttt agaaaaatag
     4321 gattcgaatc ctttgaatag atcaccatcg gattctttca ttagttgtaa catatcttta
     4381 gagctgtcac gtctcattgt ctcaaagtaa taaaaataaa gatcctcttt atcttcaaaa
     4441 tactgataga aactgcctct agggatatcc gctaatttga cgatattagc aatcgaagct
     4501 tcttttaagg gtactctaga aaactcgatt ctcgcagcct cgattagtct tttttgtttt
     4561 tctttaggca aatggaaaaa tgtctgtgtc ggcatatgga ttctcctttc tttcaagatg
     4621 acacattgtc atatgacgct atgtcattat aacacctcct acctgttttg caagacattt
     4681 gcatagtttt tttcattatc atccgataca ttaaaaaagt gataagagga atccttccat
     4741 ttgaattaat gagagttgcc cattaaaata gccacatact aaacaaagga tgagataaat
     4801 ggcccaatca attagtgtcc aagacttcaa taaattgcct ctcgatgctg acagcatcgt
     4861 tttagataca agaaatacct tagattacac aaaaaaccac ttaagccact cgctttctat
     4921 ccccgctgct atcttgccaa gacaattaaa aaatctagat ccaaagaaac tttattatat
     4981 tctaagctat acaggcaggc gatcagaagc attagccgat caacttactg ctaatggttt
     5041 tcgtgctgtt tatatcattg gtgggatgga agctcttcag tcgagtgttg cttgaatatt
     5101 gcttgttaga ttcaaaagag gctgtgacaa aaaatcgtgt cacagcctct tttataccct
     5161 gtcttttttt agttatttat tcttcaacct tatcaatatg acttgatagc cttttctttt
     5221 tcgagtaaac tgattttgtt agtcatagtt ataacaatca tagcaataaa aggagaaggt
     5281 aagcatatgg catctgtttt agtagtcaaa ggtcatcccc taactgcaga agaatcgcgc
     5341 acagttaagg cattgacgtc ttttttaaca agttataaag aaaatcatcc agatgatgaa
     5401 gtgactgttt tggaacttta tcgcgatgat attccggaaa tcgatgaaga attattatca
     5461 ggttgggaag cattacgtgc tggtgcagaa ttcacttcct tatcagaaag tcaacaacaa
     5521 aaaattgctc gtttcaatga attgactgat cagttccttg ctgctgataa aatcgttatc
     5581 gcaaacgcct tatggaatct aaatatccca acaaaattaa aagcttggtt cgataccgtc
     5641 aatgtagctg gaaaaacgtt ccgctataca gaaaacgggc cagaaggatt agtgacaggt
     5701 aaaaaagcac tgcacatcca atctaatggc ggtgtataca acggacaaga ctttgcctct
     5761 caatatgtaa aaggtatttt aaactttgta ggcatcgatc aagtagatca gctattcatc
     5821 gaaggaatcg attatgaccc tgaccgtgca gatgagttga tgcaaaatgc attagataaa
     5881 gctgctgctt taggtaaatc attttaaaaa ttgagataaa tgcatacaaa agagacagag
     5941 gaaaaaatct tcaaagcagc atttgtgcct tggatatttt cccatctgtc tctttttgtt
     6001 attctttctg ctttttcaac ggattttctt cataaagaga agagattgtt gtgtaccatt
     6061 caaaaacatg agtaatcact actttagctg ctgcataaac aggaatcccc aagatcacac
     6121 cgatgattcc gaacaatttc ccagaagtca gcagaactaa taaaatcgtt actggatgga
     6181 ttgctaactg attccctagt actaatggag agatcaagcg tccttctatt gtctgctcta
     6241 ctgcaaaaac gatcagtact ttgatgatca tgaatggacc tgctacaatg gctaaaaaga
     6301 tagccggaat catcgctaaa aatgatccta agtaagggat caggtttaaa aaacccgcaa
     6361 taatccccaa cgtgacagca tactctaaac caatgaccgc aaaaccaatc ataaacatga
     6421 ttgccacagc aaaagccaca gttagttgtc ctcttatata agaagaaact tgactattca
     6481 tttcactcag cacattcaac gtcggttttt gcatgcgtgt cggtaaaaat ttgacaaaat
     6541 aaggtgctaa ttgtttaccg tctttcaata gataaaataa gataaacggc atcgtcagca
     6601 gagccactaa aatagtcgct accgcgccga caaaacttcc aagactctga actgtactct
     6661 tagatatatc ttggatcata tcgcctgccg aattcatgaa cttatcacct gctgtttcca
     6721 actgttcgcg aaattggttg aacagcgggt cccgcaaaat ctcggttaat ttattatcaa
     6781 tcgtatctac atattgaggg aagttactga tgaagctcac tgtttgttcc tgaatcttag
     6841 ggatgatcac tacgctcccc catgcgatta gtgcaacaac caaaacaaac agcccaatga
     6901 tactgtaaag ccttggtact tttcgctttt caaagtaatc aactaccgga ttcatcaagt
     6961 aatacaagat tcctgctaaa atgataggca gacctacgat tgctaaaaat tgccagattg
     7021 gtgcaaacaa atatgaaact tttgtaaata aaaagacgat cagcaatatt aacaatacaa
     7081 caagtaaggc tgtgactact tgattattta aaaaccagcg ccaaaaccac gataccggtc
     7141 tgttcttctt attttttcct tccataattc ctcctgttag ttataaaaaa tttggcttcc
     7201 caaaccaata gcaggcagtc tatgcggatg aagatagatt ccatttgcaa tttgtccttc
     7261 ttctggacaa gcatcaaaaa tcaatgatac gtgagctact gtctttaaat tcccattggc
     7321 catcggaccg acataatcga tcgtatatac ctgatcatca aaagcaattg ttccgcctgc
     7381 tttcaaagaa aaaggttcgt cttttgatac ttcttgaatc accgaatatt ttcgtaaggc
     7441 agctgttgct gttttatcga acaaaatcag catgggttct tccttgttta ttgcttctgt
     7501 cccaatttct gtaatctttg cctgaatcat tgcactctct cctttaattg ctttcaaaaa
     7561 cagtataaca cattctcatt ctttagccgt gtggaataat tatgtgatag aataaaaacg
     7621 aaaactattt cattacaatt aggaggaatc agctcatatg atcgaaaaga taattttagg
     7681 aacctatacg cgtcgcgaaa gtaaaggaat ctatacgatc gaccttgata cagaaaaaga
     7741 agaattagcc aacctttcat tagctgttga agaaaatagc cctacctatg tagcaaaaag
     7801 taaagctggc aatctttaca cagttactag tgtggatgga ttaggtggtg ccggtgcgta
     7861 cgataaggat tttcattttt tgaatgcggt aacagagtct ggcgctcctt tgtgttatgt
     7921 agcggttgat gaagcacgtc aattactata cggggcgaac tatcataaag gtgaagtaaa
     7981 tgtctaccat atattaggag atggcgaact gaaagcagca gattcaatat tccatcaaga
     8041 agcgacaggt cctcataaaa accaagatca tgcgcatgtc cactatacgg atctgactcc
     8101 tgaccaacga ttagtcgtat gtgatcttgg tacagatcgt gtgtatactt atgatgtgtc
     8161 cgaaaacggc aaattgaatc ttgtaactac cttcactgca gagccaggaa caggccctcg
     8221 ccatcttgtc tttcatccaa atggacaatt cgcttattta tttggtgaat tagacagcac
     8281 agtccgcgtg ctttcttata ataaagaaac aggtgctttt gaagaattac agaaaatatc
     8341 gaccttgcca gaagaattcg acggtgaaaa tggaggggca gctatccgca tttcaaatga
     8401 tggcaagttc ctttatgctt ctaaccgagg acataactcg attgctgtat tcgcagtttt
     8461 tgaagatggt tcccacattc aaaacaagca aatcatctca acagaagggg attttccccg
     8521 cgatttcgca ctagatccaa gcaataattt tgtcgtgtgt gccaatcaga acaccgataa
     8581 tctgacatta tatcgccgtc atcctgaaac aggattactg gaattactga aaaaagatgt
     8641 ctatgtacca gaatgtgtct gtgtttattt tgatcgttag taagaaaagg agaatgaaat
     8701 gaatcagcaa gacgtattag acagactacg ggaagaacta aatattcctt tctttgatgg
     8761 gaaaatcgaa gataaagagt atagcgaaga ggaatatcag aaactcaaag ccgatttaca
     8821 gaactacttt gaacaatatg tacagaatgt agaaaactaa tcagctttcc atactatctg
     8881 aaaagaacat caggacaaga cttttccgtc tatcctgatg ttcttttcta caaataaaaa
     8941 accgccgaga tggttagact cgacggaaaa ggagtattta ctcgattttg agtaagtaca
     9001 aggttgttgt tggttatagg tatgtcatta tcataaagga ttttgatcac tctatcataa
     9061 aggtaatatt acatttatat tagataactc tagtttttat tgttatcaaa gatttctttt
     9121 attttttcaa caacaaatta gtcatttttt ggatggcagc tgtcaattgg tctgtcgctt
     9181 ggtcttgttt tgcttcagat gtattgaata gatcttcatc tacccctgat tcaagatcga
     9241 tactttggat catttcttca cagcctgcta catatgaaag ataagctttt tcaaaatttt
     9301 tatgaatgtc cattgctttt gctggtggac gcaaagtact gactttcata agcattgccc
     9361 gatatttttt tgttccttct tcaaataaca ggatgatctc ttcaagagtc gatttgtcca
     9421 gttcacttgt ttttccttca tcaattgcgt ttctgatcac ttcatatttc ggatgcattc
     9481 cttctccgat tgcttctgtt tccttgacga tttgatcgat ggactgcaca taatagccaa
     9541 tattcggtaa catgttcgtt ttcctacttt ctccattgtt gttattattt attctacttg
     9601 tttttatcct caaatgacaa gtacttgaaa aaatttaatg gtttctatac agctcgccat
     9661 tcttattcgt gctcaaagaa accatctgct aaactatatt gtttccctgc gacaatgtca
     9721 tattggatca attgatattc gtcgtaaatc tcttgttgcg agcgattgaa ttgcgcttct
     9781 ttataccact gtccgttttg atagtacagt tctcgttcaa acgccggaag ttcctgttct
     9841 aatgataaaa gcagctgata aaagccattt gttgtctgat tcgtctgttc cattagattc
     9901 gctgcaaaat aaaacggact ggtgattgca tcgtgagtcg tttgcttttc taattctcct
     9961 ttactgtcga acataagaaa ttgtgtttca tgcaatgttt gtttgtcatt ttttgcttgg
    10021 atcgtatctg aatagatccc tggaagatga tccccccaaa aaacaactaa agtccttcta
    10081 gaaagattct tcaattcttc cgtgaactgc ttcagtgccg tgctgctata ggaaatatct
    10141 tgcagataat tctctaagtc aagtgtccca cttccatctg aagtttttgc aggatagtct
    10201 agattatcat actttccatc gtagggcata tgtgtctgca tcgtgactaa atgaatgaac
    10261 tgaggtgttt tttcttcctt gagaagtgtc attacttctt tgtaagctga ctcatcagaa
    10321 atatatggat tattctctat cgtatccgta taggtcatcg tacgctcgct gatgaactgg
    10381 tcaaatccta atgtctgata aacatcctct cttttataca tcgaagtatt gtatggatgg
    10441 atcgctgtcg tctggtatga ttgtgcgttt aacgctgaaa cgatagaagg aagctgatcc
    10501 atttttggta caagcatcgt gtaaggggtg gtgagttgcg cattaaataa cgccatagaa
    10561 aaaccagtca atgcttcaaa ttcgatattt gctgttccac cgccatagtt ttgagaaagc
    10621 atattgccac tatatgtttg atcagctact tcataataat ctgccaatgg ctcaccagat
    10681 acttctacgc cgtttaatcg actaggatct gagaaacttt cactcatcac gaacacgatg
    10741 ttcggcgact cttcctctac agttttattt ttttcatcgg ctagcttctg gtatttttca
    10801 gtgatttctt tgatcttttc tttcgaatat ccttcaggtt catccattgg ttctaccttc
    10861 agattgtaca aaaacccacc gataaaacca gtgttatagt agttcatttt ctggctgtaa
    10921 ggtatccata gtgccgtttt attatatgct tttcgcaaca aattatcggg attgttgaaa
    10981 ttactgatat accctagcag tccaattgcc acaagcagtg tcgttaatcg gatcaattgg
    11041 aatcgccttc cttttttcag gcttcgaaac atgtaccagc aaaacaatcc tatcacggtt
    11101 cctgcggcag ctaagatcac tgtaaacagc atagtgccgg tcatatcttt cagcaatccg
    11161 atttcagtga tcatcttcaa atcgtctgga taaatcggtt cttgccgata actcattttc
    11221 atataatttg caaaacctaa tacaccgatg gctacgacat acgtaaggga acctaaaggg
    11281 acagatcctg ctagtgcaat cagaaaaata agaataatca gcaagacgag acaggctaag
    11341 aagaattttt ccgtatgcca agaaaaagca aatttcaacg caaggtctac ggatagatca
    11401 ttttgacacc actgcaaaaa taaattacta aaaacaacaa gaaaaaagat actgatgatt
    11461 gctgctgttc cttttaaaat ctttttctgt ttggtcgaaa gtctgcttat atatcttttc
    11521 aaatgcttgc tccttcattt ctatcaataa aagaatgttg cttctcttat tttagttgta
    11581 cgaaattcga aagtaaagaa cggaaagaag aattaatgaa atccaaatat tctctttctt
    11641 tatggccttt ctggtttctt taataagcgg acctttcgta ctccagaaat tttttctagc
    11701 tgttgtttca cttgattgag ctgttcaaaa tcagtactgt ctatgtcaat caatatgtag
    11761 acatgctcat tcttatggtt acgcgatata tctgcgatcg ctagctcgtt ctcattcagc
    11821 agagaaaata tctctgctaa tatattggtt ttcttttgat aaaatatagt gaatcgaaac
    11881 ggcgcttgga aaaacattcg tgcggatgga taattgaccg cttctctaac cgtaccgaac
    11941 aaaagataat cttttaaggc ttcaactgcc aaacgtccgc tgtctgccaa agcttcctga
    12001 gtcgatcccc ctagatgagg caacataagt atacggtcat tttctaagaa ctcttcttct
    12061 ggaaaatcag tcaagtattt agccagatgt tgtttttcca atgcttgcat aacagcatat
    12121 ttatcaacaa tttcacttct tcctacattg ataagtacag catctttttt cattttttct
    12181 atattcgcct gatcgatcaa tccttttgta tcttctgtca acggcagcat gactacgatg
    12241 taatccgagg tagaaagaac tgtttctaaa tctgcttgcc gaacataatc caactgggca
    12301 tcgcggatag aataacccaa gacatccatc cctaagctat agcaacttag cgctactttt
    12361 gtgcctatcg ctccaagacc aagaagaccg atggttttgc cttgcaattc tcgtcccaca
    12421 taagcacttc ttttgttttc tgcctgttct aaaatattag gacctgttag tgtttgtacc
    12481 atacgacttg cttcgattat cggacgggaa gataagagca aacagcacaa aacaagctct
    12541 tttactgcat tagcatttac acctggtgta ttcatgacga tcgtcccgtt ttcagaagct
    12601 ttttcaacgt tgatcgtgtt caccccaaca ccagctcttg aaattgctag caaatctggt
    12661 gtaagccatt catctttcac tttcgtacta cgaataacta ttccttcggc tggcaaatca
    12721 tctattattt tgaaatattc cccttgtaac ttttctatct cttgttctgg aatagcatca
    12781 atcaaatgaa cgtgatacat aaaaccccct ccttactaac aagtatctcg aaatttctgc
    12841 aattagacaa ctgtttacca tttgacttcc tagaagcaaa aagagcagtt agagcagagt
    12901 aggctgagtg ataaaaataa ggctatgaca agttactgcc ataagcctta ttttcgagag
    12961 caaaatattg agggtgagat atcttgataa atggtgttcc gttagctgac attgataata
    13021 agactaaatt tcaaaaaagt tgaaaagcaa atttcgtcaa tctcttctta tttcttaaaa
    13081 ctaagtggct ttttcacaac ctctttttat ctaataacca ctgtttccaa ctcaactaat
    13141 tttgcccacg tttcaatttg atctgttgtt agatttagcg agacaacggt atgatgaccg
    13201 ccacctgcct gaatccatga atggacacct tcatggaaat tcggtttagt tttccataac
    13261 acacgtgcaa caggtaaatt aggtgcttca gtcgttggtt caaaggcttc tacttcattg
    13321 atcagcagtt tataatgcgt accgaaatct gccatcgata cgactacccc ttctcctgct
    13381 ttcccatcaa atacaagacg cgccggatct tctctatctc ccattgataa aggagaaaca
    13441 acgattcttg gtttcgtcgc agcaagcgtc ggatctactt ccatcatatg ggattccaag
    13501 attgcttctt ggccactagc tagctcgtaa gtataatctt ccatgaatcc tgtatctttc
    13561 cctcgagcca tgattttcag caaccgatca atcgctgcag ttttccagtc gccttcccca
    13621 gcaaaaccgt atccttctgc catcaaacgt tgtacagcta gtccaggtag ttgtttcatt
    13681 ccatacaggt cttcaaaatt agtcgtaaaa gcgttatagc ctccttcttc taagaaacgg
    13741 cgaataccga tttcctgctg agcttgtact tttacatgtt cctcccatgt cttttcttca
    13801 taatcaccat agtcgaaggt atacaattcc ttgtactctt caaataattg atcgacttct
    13861 tcgtctgata cgcgatcgat tacttgtaca agatctccga taccaaaata atcaacagtc
    13921 caaccaaatt gaatctgtgc ttccactttg tctccttctg tgacacccac gtttctcatg
    13981 ttgtcaccaa aacgagccac ttttattcca aaactttcat tataggctac tgcaacatcc
    14041 atccaatcag caatctcttt ttggatctca ggtcgtttcc agtagccaac gacgatttta
    14101 ttttgtttat ttaatcgagc attgatgaac ccatattcgc ggtcaccatg agcggattga
    14161 tttaaattca tgaaatccat atcgatcgtt ttccaaggaa tgctttcgtt atattgcgta
    14221 gctaaatgaa gcaatggttt ttgtagaagc tttgtcccgc ggatccacat ttttgctggt
    14281 gagaaagtat gcatccaagt gatcacacct gctacttctt ctcgataatt gacctctttc
    14341 atgatttttg tgatcgtatc agcagtaact gctaattctt gaaggcggat tggataaggc
    14401 aattggccat tttcattcag ttcatcgacc atttcttgtg catgtttctt tacttctcgc
    14461 agtgcttctt ccccatataa atgctgtgat cctacaacaa accaaaattc tttttctcca
    14521 atattcaaca taattagcca ctccttttat ttgttttgtc cgtaatacgc attttttccg
    14581 tgttttcgta aataatgttt atctaaaatc cgttgaggca gctcttctga aaatgaattg
    14641 agctgtctgg taaataaatt catcttgcat acttcatcta gtacgactgc gttcattacc
    14701 gcactttgcg catctttccc ccaagtaaat ggaccgtgtc cgtgtaaaag tacccctgga
    14761 attgctaagg gatcaatttt gcgttctttg aatgtttcta tgataacttt tcctgtttca
    14821 tattcgtacc cgctgtcgat ttcctgttgt gtcaaaaatc gagcacaagg taccgatcca
    14881 taaaaagtat ctgcatgcgt cgtccccatc gcaggaacat ccaatcctgc ttgtgcccag
    14941 atcgtcgccc atgtcgagtg agtatggacg attcctccga tttgaggaaa tgaacgatat
    15001 aaaacagcat gagtaggcgt atccgaagag ggattgagtt taccttcaat gatatgattg
    15061 tccaagtcca caacgaccat gtcgtctgct gtcatctctt cataactgac tccgctaggt
    15121 ttgataacga aatatcgtgt ttcaggatca aaagcgctca catttcccca tgtatatttg
    15181 acgagtccgt gtttaggcaa gtcaagattt gcttggtata cttcttcttt cagttgttcc
    15241 agcattttct atcactcctt tttcttgcaa ttgatgaatc gctgtttttt caatgtcgat
    15301 cccctcacgg taacgtctca taaatatctg atagcctgct atttcttctg ctgaaggtgt
    15361 gatggtgatt ccttggtctt gtccaaacac gtcttctgcc aagaagtttt ctaaagactt
    15421 cccatgtcga tccatcatat aggctgctaa taacgcgatt ccccacgctc caccttctcc
    15481 ggctgtgtcc atcactgtaa ctggtgcctc catagcagat gctagaatcc gctgtccaac
    15541 ttctggtgtt ttaaaaatcc ccccatgccc cactaaacga tcaatttgga cattctcaga
    15601 tttcaatata tccattccga ttctcattgc accaaaagca ctggctaaat ggatccgcat
    15661 gaaattcgct aaatcaaaac ggctacctgg tgtacgtaca aataatggcc ttccttcatt
    15721 tactcctgta atgttttcac cggaaaaata accataagaa agtaatcccc cgcaatccgt
    15781 atcgccttct agcgctttgt tgaataatac cgtgaataat ttatctctgc ttatctccat
    15841 acccaaagaa ttggtaaatt cttcaaaaat actgacccaa gcattgatat ccgaagagca
    15901 gttattcgta tgaaccatgc ctactagttc tcctgaaggt gtagtgacca tgtcgatttc
    15961 cggatggaca ttttctagtt ctttttctaa tacgatcata gcgaaggcgg aagtaccagc
    16021 cgaaatgttc cctgtccctt tggctacact gttcgtagcg accataccgg ttcctgcatc
    16081 cccttctggc ggacaaaccg ggattcctgg tctcaaattt cccgtagggt cgatcagata
    16141 agcccctgat tcgcttaact tgccagcttc ttctcctgct actagaactt taggcaaaat
    16201 gtgatccaag tcaatcgcta cgtgcgcttt ttcgattaac tgaccaaaaa tatttttcat
    16261 ttcttgatgg taggttttcg ttgaaggatc gataggaaac atgcctgatg catctcctac
    16321 gcctagtact ttctcaccag taagctgcca atggacataa cctgcaagcg ttgtcaaaaa
    16381 attaatttct ttcacatgtt cttctttatt caaaatagat tgatacaaat gagcgatact
    16441 ccatctctgc ggaatattgt attgaaattt ttccgttaat attcgttctg cttcttcagt
    16501 gattgtattt cgccaagtac gaaatggtac tagtaactgt tccttgctat caaatgctag
    16561 ataaccgtgc atcattgcac tgaacccaat cgacccgatt gtcgtaagat tctcgccata
    16621 gatttcgaat acttctgctg ccatttttcg gtaactgacg cgcagtcctt tccaaatatc
    16681 ttctaatgaa taggtccaga taccattttc tagtttgttt tcccactcat aactaccagc
    16741 ggcaatagga gtaaaagatg aatcaatcaa tacagctttg atcctagttg atccaaactc
    16801 aatccctaaa gatgtacgac catctatgac atctaacata ctttgcgcat ttacttcctt
    16861 cataatgatt taactccctc cttctcgtca aacctgatca aaccgtcttt ttagtagcgc
    16921 ttacaatgat tattgtatac ttttgtacgt acatgtcaag cagttattta caagaataca
    16981 ataaaaaaca cttgttttgt acgtacataa gttataaaat gaaattgctt acaaaatctg
    17041 atcaaccgcc ttctcgaaat tctagaagga gagaatactt atgaaaaaag aaaaaaaagt
    17101 ttcctcatcg tttatttatt tttttggcgc atttggcggc attctatttg gatatgatat
    17161 tggtgttatg accggcgcct tacctttttt acagcatgat tggggtttgg caggtaaagc
    17221 ttctttgata ggatggatca cgtcttcggt catgttaggt gcgatccttg gcggctcttt
    17281 atctggtctt ctttctgata agcttggacg acgaaaaatg attcttcttt ctgcacttat
    17341 ttttatggct ggttctgtcc tttctgcatc tgcccctcac aatggttctt attttctgat
    17401 tgcagcaagg attcttctag gtttagctgt tggcgctgca tctgccctag ttcctgctta
    17461 tatgtctgaa atggctcctg ctagactaag gggaagattg tcagggatca atcaagtgat
    17521 gattgcttct ggcatgctcc tttcctatgt tgcagattat ttgctaaaag ggttgcctga
    17581 aacgatggct tggcgcgtga tgttagggct cgctgctgtc cccgcgctga ttttattttt
    17641 cggtgtttta gctctaccag agtcaccgcg ttttcttatg caatctggcc gcttggaaga
    17701 ggcaaaaaga gtattgaact atattcggac accaaaagaa gctgaacagg aattcgaaca
    17761 aatccagctg aatgtcaaac aagaaaagac aaccggaact tcttggcata ctttgttttt
    17821 agaaaaatat cgttccttag tcattgccgg tattggtgta gcagtattcc agcaatttca
    17881 aggagctaat gctatttttt actatattcc gctgatcgta gaaaaagcga ctgggcatgc
    17941 agcgagcgat gcattgatgt ggccgatcat ccaaggaatc attttagttg ctggttcttt
    18001 gctctttttg gttattgcag acaagttcaa tcggcgaact ttattgaaaa taggcggtag
    18061 cgtgatggga ctttctttca tcctaccagc tgttttagga actgtactgg atgctcatac
    18121 aaattcgttg ttgattctct tgtttttatg tatttatgtc gcattttatt cttgcacatg
    18181 ggctccactg acatgggtaa tcgtaggcga aatattccca ctagctgtcc gcgggcgagc
    18241 atctggccta gcctcttctt ttaattggat tggttctttc ctagttggct tgctttttcc
    18301 tgtgatgact gcttctatgt ctcaagaaat cgttttcggc atttttggga tcatctgctt
    18361 tttaggggtt ttatttattc aagagatcgt accagaaact cgtgggaaat ctttagagga
    18421 aatcgaacaa agtgcatcta aaaaaactta tcctaaacgt atttctatcc atcattctta
    18481 aagaggttgt gacagaagtg gtcagcttca agaaataaga aggaaccgct tagtttccag
    18541 tcacaaggaa caatttcaaa aaacagcttc tcatgtttga tgaatattgt gacttgtgac
    18601 cagttggtag gagaacaccg tttagtggag aggtggtgaa agaaacgttc agccttgagc
    18661 gatgacaaaa gctctcacaa acattgcgac gagtaaccgt aggagcaata agaggcggta
    18721 aaaacccgtc tcttattttt cgttttcttt cactgtttcc cgttcaacta gtacaggttc
    18781 atagagaata tttggctgtg cctgtccttt ttcaatcgtt gtgacgatcc accgtgcggc
    18841 atcttgtccc aacttttctt ttggatgcgt caatgttgtc aattttttat tccctaaatg
    18901 gcttaaagaa gaatcgtctg ttcctacgat cgataggtca tctggaatat gatagccatt
    18961 ttctgtcaac ttatctagca ttaaactagc tatttgatcg ttatagcaaa tgatgccatc
    19021 taaagcttgt tcttctttca accgttgtac tgttttttca gcgattgttt ctcgtgtttc
    19081 cgtggtgaaa gtaatgatat cttccgtcaa aaaacgcaca ttatactgtt cacacgcgct
    19141 gataaaacct ttcatcctgt attttccttg aagatcgtcg atttttgtga tgaacaacag
    19201 acgctgatgt ccttttttta tcaaatattc tgctgccata aaaccgactt tcacatcatc
    19261 taaacaaata taagaggcat ttaactcttc ataagcagca ttgatcatca ccatcggaat
    19321 gccttgttct ctcaaagcaa cataaagtgc taagtttggg ttatactgat tacttttcgt
    19381 aggctcaacg atcaaaccat ctaccccata agcaatcatt ttcttcaaac actctttctc
    19441 caattcgtga tcgttattcg tactggctaa aagcaatgaa tacccagatt ctcgtaattc
    19501 attttcgatt cctcggataa tcgacggaaa aatataatca gagagatatg tggtgatgac
    19561 accgatcgtt tttgttctgt tcaatggtgt tttttctttc ttatagctgt catctacata
    19621 tgtgcccgac cctttttctt tacgcagata gccctcattt accaacacag cgattgcttg
    19681 ccgaatcgta tgtctgctga cgtcatatat ttcttgcagc ttgaattctg agggaatggt
    19741 tgtatttact tcgtattcct cacgaaggat cttttgtttt atctcttctg caatatcttg
    19801 atattttgcc atttgccttg ccccttttta tttgtacgta catatatcat aacgagtctg
    19861 caaggtttat tcaagcaaaa atcaaggttt cttgtgctca taaggcatac ggaacaggtt
    19921 caccaaattc tggaaatcct tgctcattcc acgtaaagca ttgcgcgttc gcgtgccgat
    19981 taggattgtc taacggatcc cctttttggt tcttctctgg tcgagcatga tagatcaaaa
    20041 tatcaaagca cccgtcttct gaaaccgtaa acgagttgtg accaggacca aattgcttat
    20101 ttttttcaga agaaacgaat actggctccg ataatttatg ccatgattct tttaataaaa
    20161 gattcttgtg ctcatcagcc cacagcaggc ccatggcata gttttcatct gttgcactac
    20221 cagaatacgt aatgaatatt ttcccattgc gagtaaggac tgctggacct tcatttactg
    20281 aaaaaccccg tttttcccat tcatactcag gtatagaaag gaggatctgc ttccccttta
    20341 acgtccaagg attatccatt tcggatagat aaagattaga attcccagta atttcaggat
    20401 cttgttgggc ccacacataa tatagctttc cttgagaaga gaaagttgtt ccgtctaaac
    20461 tgaaagtttc ccttttcgtt tttatttgtc ccttttctat ccaatctgta ttcattggat
    20521 ctatatgctg attttcaagt acgaacatgc ggtgatgatg agattcatca cgtatagttt
    20581 tatgattgct tgcagcaaag taaatatacc attttccatt gatataatgg acttcaggtg
    20641 cccagatcaa ttcactcatc ggtccttctt catgagcctg ccatacaatc aggcttgcag
    20701 catgttctaa ttcattcagt gactttgccc ttcttaattc aatcacttgg tagcctggaa
    20761 ccgatcctgt aaaataataa taaccatctg tatgtttata tacccaagga tctgcccgtt
    20821 gccgaacgat aggattatta taaagtgtct tcatcataac aaatttcctc acattttctt
    20881 tattctaatt acattccaag agtatttttc tatccctaca tttaattcgt catgtttttc
    20941 tattgaaaaa tagtttattt caggttttat tttttctggt tcttcacgtg tatttttgtc
    21001 caacagatcg ctactggtta atgtgtagtg ctctccttga tctagcaaat tgaaatcatg
    21061 ttcaatcgtt atcttttgtt gttcatttgt gcgattgatc aagaaaatag tcagctgatt
    21121 gccgttatct acgatcacac tgtccacata aggaacattt tttatctttt cacaatcata
    21181 aacagggcaa atgatttgtt gtttcaatac ttgaccttta gcatatttcg ataagtgttg
    21241 catcacataa taagttggat tcctccatgc ttgtccttta gcatctgtca gtattaaagg
    21301 tattgtgttt actaacaatg attgacaact aatctttacg cgatctgcgt gtcgtaaaat
    21361 agccagccct aatgaaccaa ataataatgt atcttccata gtaaagtaac accaatcgat
    21421 gggactaccg acttcaaaat ccctatgtct tttttccggt tgggcatgta cattccattc
    21481 atcaaacgct agatacattg ttttctcact tctcaaatat ccttttacat aatcacaagt
    21541 agcaacgatt tcttcaattt gacgatcgaa tcgataagct tttgcaaggt atgtcgctgt
    21601 atcatcacgc tcatttttag gaggtttagt caagtcttct tcatcatact tatcaatata
    21661 gttatgcaaa gctaaataat ctacattctc ataagcttct tctaatgcga tacgatccca
    21721 ttcagggtac gatggtaaac gtggcgtaga gcttccaact aagattgttt caattgaatc
    21781 atccactaac ttcatgactt ttgaggcttc atttgctaac ctaccatatt cataagcact
    21841 cttagccccc acttgccatg gaccgtctag ctcattccct aaacaccata atttaacgcc
    21901 aaaaggcttt ttttgcccat tttttattct taaatcactc cagaaggttc cttttggaaa
    21961 attacaatat tctactaaat tttttgcttc atcaattcct tttgttccta aattcaccgt
    22021 gaatatcggt ttcgcttgta catgactgat ccatttaaaa aattcgtgga gtccaaaaga
    22081 atttggttct atacctcgcc atgctaaatc aatttttttt ggtcgttgtt ctttcctacc
    22141 tacagtatcc acccaatcat aaccagatgt aaagtttcct ccaggatagc gaatgacacc
    22201 taattctaat tcctttacat aagagaggac atcttgtcta aacccgtcac catcagctgt
    22261 ttcatggccc ggttcataaa tccctgtata gacgacactt cccatatgct caacaaatga
    22321 gccaaacagc cgagaactga tctctcctac cgtaaaatcc tctctgattt ttactttcac
    22381 ttcttcgtcc aacagctttc cctacctttc atttcctata gtcaagataa tagatacaag
    22441 tttccatacg ccaccagcaa agataaaaat aaaaggaggg aaaagaaata tgagcagtac
    22501 aaatcctaat aacaatacgc aacaaagaat atttctcaaa aaatcaaaaa atactttcca
    22561 tgcactttgt tcaaaaattt gtaaaaatgt gatatctttg ttttcagaaa tcacatatat
    22621 ccaggataaa agaaacatgg aataaataag taaaactaca tatccactaa ttgaaagtac
    22681 gattgtctgt tcttctaata attgattaac aagaaaataa ataatgatcg ttaacagact
    22741 aaggaacaag ttcttaccaa aatgttgctt tattccttga aagaaaaaat aaatgatatt
    22801 tcctgatccc tcacctttcc attgcgccat tacataaaaa aacagcacat gtagcaggca
    22861 cgatagtaat aacaggcaaa cacacgatta cccagagaat acctaataag atgtaatcag
    22921 aaaccacaat caactgtcca taaagtttag tctcaactat tttcatcttc ctcactcttt
    22981 cattccagac atagctgttc cttgaacaaa atatttctgt gcaaaaatat aaaccactag
    23041 taatggcagc attgaaataa ccgttccagc cattacaggt ccataaaaag aaatgttctg
    23101 ccctgtaaat aaagctaacc ctgctggtaa agttctcatt tttgaactac ttgtcaatat
    23161 caatggataa agcaagtcat tccaactatt catcagcgtg aaaatcccta atgataaaag
    23221 agtaggtttg ctcaatggca acatgatttt caaaaaaata ttaaactcac ttaatccatc
    23281 aatgcgtgct gcctcttcca aagaatctgg taaagtaata aaaaaggaac gcatcatgaa
    23341 gataccaaat gcagttgtca tacgaggaat gatcaaacct gcataagtat caagcatgcc
    23401 aagcaaattg acttcaataa atagaggaat catgaagact tggaatggga tcatcattgt
    23461 cagcaaaacg aaatagaaca aaactgattt tcctttgaaa cgcatacgag caaatgcata
    23521 ccccgcaaga gaatcaaaga atacagaagt gatcactgtc cctccagcaa aaatcactgt
    23581 atttttgatg taatctaata aagggatcgt tgtccaaacc ttaatatagt tatctagggt
    23641 atagctatct gcaaatattc taggcggaaa tgagataatg tctttttcgt gtttaaaaga
    23701 agaaataatc agccacaaaa aaggaaacgc aataaccaac aatataacta gcatactaat
    23761 cgttcgaatg atttttttac cactaactgc ttttcgacta ttcacagtaa ctgtaatcga
    23821 gctttctggt gccatacagg tttccctcct atttcatttg tttttctttc cgtgacatgt
    23881 acacattagt ggagatagct atagttgcaa caatgataaa caaaaccgaa gacagtgctg
    23941 atgcatagcc caattcataa ggtgctgtaa atcctcgact gtaaatatat tgaacagctg
    24001 tttctgtctt aaattgtggg ccaccagcgg ttgcaacata tacttggtca aacacttgca
    24061 tcgaaccaat cagattcgtt aaaatacaaa aacctaagga gggaacgatc tgaggtagcg
    24121 taatgttaaa aaactgctgt cgatttgttg caccatccat ttgagcagat tcatacaaag
    24181 agggagagat tccctgaata gcagtcaaga gaatcgtcat agtaacacca aaattcttcc
    24241 aaacagtcat gatggctacc gtcggcatag caagggttgg atcgcgaaaa aattgaggga
    24301 tcggcaagcc gacttgtgaa aacaagtaag gaatcgcccc tacattcgga tcaagcaaca
    24361 tagaaaaaat aatcgcaatt gacgtcaatg aacaaataac tggaatgtaa aatgtcgaac
    24421 gacaaaaacg attgaatctg gtatttttag ataatgctac tgctgctaat aaaccaacga
    24481 taatttgtgt tggcgtttcg agtacggtga aatataaaga atgaatcaac gaattaactg
    24541 ctcgttcatc actaaatata cgtgtgaaat tttcaaaact tacaaaattt cttgatgtaa
    24601 agaaaatatt caaatctgta aaactaatag caaatgttcc taaaagcggt atgacagtaa
    24661 ataataataa aactaaaaaa gatggagtta aaaacaaata cgcagcacga tcaggacgat
    24721 tccaatattt ggtgaatccg ttcatatagt ccacctcatc tttcattttg ataaaatata
    24781 caatcttggt ttaaacgaat ctgaataaga tatccgaaca atcgctgtga tttttgcaat
    24841 aacacctatc tgcaaatact aggtcgatca ttcagatatc tgtatcttgc caacagtcta
    24901 tcctgtataa agttctgtac tatttttgca gtaattgatt gatggcatca tctgcatcgt
    24961 tcatgagtgt ctcaggatct tctcctgcta ataatttttc aatcagtgga ttgatgatat
    25021 cgttattgat cgcagagatt tgggtaaaac ctggtaaata tggctctgca tagtccattt
    25081 gtttcgataa ttcagataca ataggatcat tttttacttc ttcatctttt gctactgaat
    25141 ccaagtaggc aggaaaacca ttttcgatac tccatttttt accaatttca gttgtattcc
    25201 aatatttcaa aaactcatag acagcttctt ttttattatt atctgtactt gccggaatgg
    25261 catatcctac gccatctaaa atagctgttt ttttgtctga atcactccct tgtggtaagg
    25321 tagtcacatt ataatcaatc tcgtttgctt tcaatccgtt atttaaccat ggcccattga
    25381 tttcaatggc tagttgacca gcattcatta aattgtccat ttcggcgcca gaaatcgatt
    25441 ctggaccagt cttgtctaca tggatcattt tttggatcgc ttttaacgtt ttaaggttct
    25501 caggagacgc aaattcagac ttagtataat catcgttcac taatttaccg ccatttgcta
    25561 acatccagtt atataacggt gcagttccat ccttattgaa gacaaaacct gatacatttt
    25621 tactactatc agttaatttt ggtgccattt ctgtcaattc ttcccaagta gtaggtggtt
    25681 gttcagtatc taatccagct tgtttaaaca aatcattatt ccaatacata tacatgcctt
    25741 gtacctgcat ggggacaaaa tactgtttac cttctacttc acctaattca atagccgttt
    25801 ctttaaaatc agatttatct actccatcat attcccagaa atcgtctaat ggttgtaccg
    25861 ctccgttttc tacatactgt gcaaaatctg gataatttaa tgcaataaag tcaggtgctt
    25921 ttttagaaga aatcgctgta ggaagttttt cattcaaatt ggcccaagtc atgatatcca
    25981 tttcaatttt gatgttttta tcatttgttt tattaaattc attaacgatt tcttgcaata
    26041 tttcaccatc agatgcagta aacccattcc aaaaagtcaa agtcacttct ttatcagaat
    26101 cagattctgc tgaacttccg ccaccgcaag ctcctaaaat acctgttgca gctaccaaca
    26161 aagagccaat taaccatttt ttacctttca ttttttgttc ctccttcatc tgataaacga
    26221 catctgacca cattccaaga tagcggtttc aataaacaat tgattttccc atcttcagct
    26281 tttacatttg ttgaatgact tggttttact tgttcacttt taggaagatt agttgctttt
    26341 gtatcaaatc cactcatttc agaaaaatca atcactccct ctaatgataa ttcagacaag
    26401 tgaacagtta gattcatttc ttcttctcca cggttaactg caaatatgac aagttctttg
    26461 tcatttatta cggctatact ttctaaatac ggcacttctt caaaatcttc cgtcgcatag
    26521 tttgctgaac gaatttgtgg gcttaacacc tctccttgtc catacacagc agcttgcata
    26581 aatggataat agatcgtctg tctccaagct tctccgtttg tttctgtcct gattggtgca
    26641 ataacattta ccaattgagc aagacaagca atctttactc tatctgcatg tttcaataaa
    26701 gtgattaata gacagcctaa tagtaatgca tcttcaaaat tatagttatc ttctagtaaa
    26761 ggaggagcaa tctgccaagg cgctgcttgc tcatcttgtt ccgctgaatg ataccaaata
    26821 ttccattcat caaaggacag gttgatctgc ttcttactat gtttcttcgc cttgactgta
    26881 tcgcacatcg ctgtcacttc agaaatgaac cgatccatgt ctaaggaacg tgcaagataa
    26941 tgagaaagat catttttttg gttgccataa tattgatgca gagacaaata atctatttga
    27001 tcgtacgctt gatcaagaac tgttaactcc caatcaccaa atgtaggcat ttgccgattc
    27061 gaacttccgc ataaaaccac ctcaattgaa tcatctacga gtttcatcgc cttagccgtt
    27121 tcctctgcta accgtccata ttcttccgct gttttatgtc caatctgcca aggaccgtcc
    27181 atttcattcc ctaaacacca tgtcttaatt ccaaaagggc tctcttgacc attcgaacgc
    27241 cttaaatcac tccaataagt tcctttagga aaattacaat attcgactaa attacgagct
    27301 gcatctactc cacgagtacc cagattgaca gccatattga tttcggcccc cacatgctga
    27361 caccagttat aaaattcatg aatcccaact tcattcgttt caattgtccg ccaagctaaa
    27421 tccaaccttc taggtctatt tgctatgggc ccaatactgt cttcccaacg aaatcctgac
    27481 acaaaatttc caccaggata tctaatcatg ggaatgttca attcttttac caagtgaatg
    27541 acgtcttggc gaaatccact tttattagct gatggatgat ctggctgata aatcccttca
    27601 tatactgctc gtcccatatg ttcaataaat gaactgtaca accgcggatc aactttgcct
    27661 acacgcttga cactactaat caacattgtg gcttccataa ctgacctcct ttaatttata
    27721 catgaataat acacctcgtt gaaagcgttg tcaataatat aaatgttaaa cttacttatt
    27781 ttttatcgat tttaattaac caaaatatta ataatgatta aaacaaataa tttaatataa
    27841 cttttattaa caaatatgtt aatatataag aaaaaccttt taagaggtga tatatatgca
    27901 actacaaata aacgaagaat ccttaccggt atatgaagca ttagctagta aaacaaggat
    27961 caagatcatc cagctacttt ccaaaaaaaa gatgaatgtc aaagatttgg caaaagaact
    28021 tggagtgagc agtgctatca cgacgatgca cgtgaaaaag ctagaggaag caaacatcat
    28081 caaaacagaa aaagtaggac aacaaaaaat ttcgagcctt cgtgtcgata aaatcgatat
    28141 cagttttcca gaaaaaatat tcaatgcttt tgatacgaaa gaaacatcga tacctattgg
    28201 tcactataca aattatgcaa ttgaaccaac atgcggttta gctacgatcc atgattttat
    28261 cgggaaagtg gatgaaccac gctattttat ggatcctcga aggatggatg cccgcattct
    28321 ctggtttacc agcggatttg tcgagtatca ggcacctaat tttttaaata cagaggatac
    28381 attggagatg ttggaagttt ctgtggaaat ttcttctgaa tttccttttt caaatgacaa
    28441 ttggccttca gatatcactt tcagcctaaa tggtgtggag ctaggaacat ggacgagccc
    28501 tggagatttt gctgatatcc gcggtaaata tacgcctgat tggtatccag ataatcttaa
    28561 tcaatacggc ttgctgaaga cgatccgaat taccaaacac ttgacgaata tgaatggaga
    28621 acccttgtca aacatcacga tcaacgacat ccctaaagag caagacactt ggcatttgcg
    28681 aatcgaagtg aaagacgatg ccaaacatgt ggggggctgt actttatttg gtaaaggatt
    28741 cggtaattac gatcaggata tcaaattaaa agtttactac agctgatatt tttcttttct
    28801 attttataaa acaaaaacag ccaatcccta tgaagggacg gctgtttttg ctttattgtt
    28861 atttccagaa atcatccaaa acggaaattg gcaaatgtcg tttatgttgt gtcttgttcc
    28921 accatgcttc gattttttct tgtgcttgag cgggaacttc ttttccttct agataatcat
    28981 caatttcatt atatgtgaca cctagtgcga cttcatctgc aatcattggt ttcccatctt
    29041 caagatctgc agtcggaatt tttgtgtata atttttccgg tgcattcaat gcttgaagca
    29101 attgtttccc ttgtcgtttg tccaaacgga ataatggcaa aatgtcggct ccaccatcac
    29161 caaatttcgt gaagaatcca gtaatgtttt ctgcagcatg atctgtccct aatacggctc
    29221 ctgctctttc tccagctacg gcatattgcg taatcatacg ttgacgtgct ttgatatttc
    29281 ctttgttaaa atcgctgatt cccacacctg cttcgcttaa tacttgtact tgtgcatcaa
    29341 cagctggttt gatatttact cgcagactaa catcgggctg gataaagtca agagcagctt
    29401 ttgcatcttc ttcatctgct tgttcaccat aaggaagacg aacagcgata aattgatagt
    29461 tttcatcttt tgtttcttca cgcatttctt ccatcgttag ttgcgccaaa cggcctgcta
    29521 aagtagaatc ttggccgccg ctgataccta gtacaaaagt tttaagaaac ggatattttt
    29581 tcaaatatgc tttcataaag tcaatacttt tacgtatttc ttcttttgga tcaattgttg
    29641 gtttgacacc taattcattg ataatttctg tctgcaggct catttattct cctcctatgc
    29701 ttctgtatga agttctgcta cgcttttttt cattcgttcc atgatagcca ttttatggtt
    29761 ccagcattca gtagacagat cgactgggta tttttgcgga ttcaagtctc gtttatactc
    29821 ttcccatagt gaatctagat tttcttttgt atattctttg atttcgttta gtgcaggtaa
    29881 ttcgtaaact ctttttcctt cgataaagat atcttgtaaa actgggcgag ctgtaaagtc
    29941 tcgaacagtt ttattgataa acgtatgcac tggatggaac atgaagatag cttcttcttc
    30001 tcgagggtct tcatcccata atgtcacgta gtctccttca gatttcccat caaaatttcg
    30061 agtgatgcgc cacacttgtt ttttccctgg agtagttact ttttctgcat tgcttgataa
    30121 cttgatcgta tccatcattt ttccttcatc atcttcgatc gatactagct tgaatactgc
    30181 accaagggct ggctgatcat aggctgtgat caattttgtc ccaacacccc atacatcaat
    30241 tttagctttt tgcatcttta aattcaaaat cgttgcttca tccaagtcat tcgaagcata
    30301 gatttttgct tccgtaaatc cggctgcatc taattgttcc cgaacacgct tagatatata
    30361 ggccatatct ccactgtcga tgcgtacgcc ttggaagttg attttgtcac ctaattcttt
    30421 cgccacgcga atcgcacttg gcacacctga tttcaacgta tcataagtgt cgactaagaa
    30481 cacgcagtct ttatgggttt tagcgtaggc cataaatgct tcataatcat ttccataaga
    30541 ttggactaac gaatgagcat gggtcccgct agctggtatc ccaaatatct tcccagcacg
    30601 tacattgctt gttgcatctg ctccgccgat atatgccgct ctagttcccc agactgctgc
    30661 atccagttct tgtgcccgtc tagttccaaa ttccaatagt ggatcttctc cgatgacaga
    30721 tttgatacga gctgcttttg tcgcgatcaa cgtttggaaa ttgaccatat tcaacagtgc
    30781 tgtttctact aattggcagt gcgctaaagg cccttccact tggattaatg gttcatttgc
    30841 aaaaactagt tctccttcac gagcagaacg aactgttgct ttaaattcaa aattttgtaa
    30901 atactccaaa aaaccttcag gatagacttc taatccacgc aagtaagcaa tatcggaatc
    30961 attgaacgtc agattctcta aataattgac taaccgttcc aatcctgcaa aaaccgcgta
    31021 tccgtggtta aaaggcattt ctcgaaagta acattcaaaa acagcatgta aatcagctcg
    31081 acctaattcc cagtatgtct gcatcatatt gatttgatat agatccgtat gcagcgtcaa
    31141 actgtcgtct gggtaagtat tattcatctt gtattactcc tcttggcaag ttttcatttc
    31201 ctacccatta taacaaaaaa aattaatagg aaaagaaatc ttccattttt tctgaaaaag
    31261 cacatgtttt acggatattt cttgctaaaa atgaactcca tctgctaaaa ctatcctttc
    31321 ttattggtat ttaacctaaa cgagaaagaa tacttatttt attcaatgta tccgagacac
    31381 gaagaaatta gcgttttcta tttttcttac ttgataaaat aagtagattt tcctactaca
    31441 atcgtagccg ttaagatacc gatgattgaa caaatataac caaatgtctc tacaacataa
    31501 tcaatggcaa aagtttttga agcaataata cgtctttcct tttttgcttc ttatccccaa
    31561 agaaacggat ataacttatt atgtattgaa tttttttgga aaggcgaatt atgacaagat
    31621 ataccttgcg ttgaaaaaac tcgcggaaaa aatatcacac gtttttaaaa agatacaaag
    31681 taagaaagca gctgtcaata gaatggaaac aaaaatggcg agacatcaat cagtctcgcc
    31741 ttgtttttta ttgtatacat tagatatgga gcaggttacc ataaagatga ttattagtcg
    31801 ttattaaata gaatccttcg tatttttttg ttctatcact acaatatctt tatttggacg
    31861 tttgaattgt attccggcac gttctagctc ctgtttcact cctacatgga ctttgacatc
    31921 ttctcgtgtc atttttaaaa cgtgatgaat cgcatagtcg atttcttgcc ttgtgatttt
    31981 tttcttcgta ttgatcatca cgacttgctt tttatcatat gtgtctacca atagcagttg
    32041 tgttcgatct aacgaaaata atttgtaata attaatagcc gtattcccaa aaaagaattc
    32101 cactacttta ggataaaatg tcttaatatt taaattacta ttcacaggtg tttcgattag
    32161 cttcatctca ttcctctttt ctatatagtc gatttagatc caatcttaag ttatgttacc
    32221 atctttccta gcattaagga atcggttaca attgaacctt taaagacaaa aggatttacc
    32281 ttttatcact taatagtata acataatttc gtgagaaaaa aatacaattt tttcttgacc
    32341 atctcgttac gtaaaggatt atgcttacat ttgtcaggag gaaaaataat ggagtacaca
    32401 ataaagaaaa tgtcagagat atcaggagtc agtccgagaa ccttgcgctt ttatgatgag
    32461 attggactgc taaaaccagc taggatcaat tcttcaggtt atcggattta tggcaaaaaa
    32521 gaagtcgatc gtctgcaaca catcttattt tatcgaacaa tggcattcaa gttggatgat
    32581 atccaagagg tcttagacaa tccatctttt gaccaccaga aagctttaat caagcatcag
    32641 caaatgttgc tggaaaaacg ggcacaaatc gataccctct tgacaactgt ccaacagaca
    32701 cttgatatgt acgaaggagg aagaaaaatg agtgacaaag aaaaatttga agggtttaaa
    32761 caacaaaagt tgaaagaaaa tgaagaatcc tatggacaag agattcgaca aaaatacgga
    32821 aaaaaaaagg ttacagcatc caatgaaaaa tggatgaata tggataaaga aacgtatgaa
    32881 gaaatgcaaa ctgttgaaaa gcagatgtta tttgatctca ctctttactt aaaagaacca
    32941 gaagatgaaa gcttagcaga ccgtatcttc caagctcata agaagtggtt ctcttacagc
    33001 tggcctgaat atcagccaaa agcgcataaa ggactaggaa tgatgtacga agccgatgaa
    33061 cggttcactg catattatga cgagcgaagt ggtcatggtg cagcaaaagc tttaaatgaa
    33121 attatccaaa aaaaggcgta atcttttaca tgatccaaca aaaaagtaca cgtaaaatga
    33181 cctaataaca aaacagcaga cacccaagtt agatttttat gctaactttt ggtgtctgct
    33241 ccattctttc acaagttttt tcatcctact ttaaatatat tcatcgttga ataaacgtat
    33301 aaggtatttt cactttatcc tttttttctg taagaaacaa ttgaaatgcc atttctccgc
    33361 aagcttccag atggtggtcg atggttggga aaccaagaag ctcgctgatc agcaaattat
    33421 cgcgtccaat caccactggt gtcttatctt gcagatagct ttgcaagatg cctgctgcaa
    33481 ccatatccga atttgtaaag acaccatcaa ctccaagctc tttaaaaaag aagcctgctt
    33541 gttttccttt ctctgcatct atacaatccc aaaaaacaag tgattcatca aaagatggaa
    33601 aaagttgatg acatagctgc aaagtgattt ttgagttata acttagcctg ccacttcgcc
    33661 ccaacgtgat gcccaattgc tttatacctt gctgcttcaa ataagtaaga ccttctgtaa
    33721 ttgattgttc tcgatcaata aagacacagc ttgcctgttt tcccttgatt tcttcacaaa
    33781 aaactagagg tccatatttt tgatatgcca ataaatcatc tagtgtattg gcacgagacg
    33841 taatgatcaa tccatcgaaa gctttagctg caaattcttc aagatacctt cgctcttttt
    33901 ctttatgata gcccgtcggt aaaagtgtca ctttgtaatc ataatcaaac gctgcttcaa
    33961 tgatcccact gatcaactga tcaaaatacg gatgattggt ataaggcaga atcactccaa
    34021 tgcttttcgt ttttccataa cttaactgtc tggcatttgc attagggata taatcgactt
    34081 ctttcatgac cgcaagtatt tctttccttt tttcctcatc tacatatgga tgtccattga
    34141 ttacacgtga aatagtagaa actgaataac ctgtgagctt tgcgatatct cgaatgtttg
    34201 ccactgctgc ttcgccacct atacaaaaag attttcttgt aaatagtcta ccacagctgg
    34261 accgcattca aaaaactgat acatttttcc ttcatgcgaa aaactgatcc gctgcccgcc
    34321 ccaatatata tcttttgtca aattttcgat ttcattcatt ggtatttctt ttactatatt
    34381 cctattcaac ccttgaaaac tgtacaacgt taatacggat cccttgaact cgacaaacgc
    34441 ataaaaataa ttgttcgttg tgccatctgt tatctctaca taagtattca ttgcaagccc
    34501 tccttttgat actttgagta tagtgtatga aacgcgtctc atagcaagga gtttgttttg
    34561 ccaaagaaaa gttttattcc tctttcatta ttaccaaagt ctcttatttt aaattgaata
    34621 cattataatg atactgtaaa tatatcttta ttattagtga at
//
LOCUS       DAFENC010000029        33263 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.029, whole genome shotgun sequence.
ACCESSION   DAFENC010000029
VERSION     DAFENC010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33263
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.029"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(41..229)
                     /locus_tag="LP493_001760"
     CDS             complement(41..229)
                     /locus_tag="LP493_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HBL2133912.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            499..861
                     /locus_tag="LP493_001761"
     CDS             499..861
                     /locus_tag="LP493_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBL2133913.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            913..2595
                     /locus_tag="LP493_001762"
     CDS             913..2595
                     /locus_tag="LP493_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HBL2133914.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKETPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            2712..4748
                     /gene="recG"
                     /locus_tag="LP493_001763"
     CDS             2712..4748
                     /gene="recG"
                     /locus_tag="LP493_001763"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HBL2133915.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKEFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LLTGSTKAKERRELLEKLEQGEINIVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            4797..5798
                     /gene="plsX"
                     /locus_tag="LP493_001764"
     CDS             4797..5798
                     /gene="plsX"
                     /locus_tag="LP493_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HBL2133916.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            5920..6162
                     /gene="acpP"
                     /locus_tag="LP493_001765"
     CDS             5920..6162
                     /gene="acpP"
                     /locus_tag="LP493_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBL2133917.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            6430..7434
                     /locus_tag="LP493_001766"
     CDS             6430..7434
                     /locus_tag="LP493_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2133918.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            7435..8379
                     /locus_tag="LP493_001767"
     CDS             7435..8379
                     /locus_tag="LP493_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2133919.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            8379..9341
                     /locus_tag="LP493_001768"
     CDS             8379..9341
                     /locus_tag="LP493_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2133920.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            9368..10282
                     /locus_tag="LP493_001769"
     CDS             9368..10282
                     /locus_tag="LP493_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2133921.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            10308..12089
                     /locus_tag="LP493_001770"
     CDS             10308..12089
                     /locus_tag="LP493_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL2133922.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            12437..13123
                     /locus_tag="LP493_001771"
     CDS             12437..13123
                     /locus_tag="LP493_001771"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HBL2133923.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            13143..16724
                     /gene="smc"
                     /locus_tag="LP493_001772"
     CDS             13143..16724
                     /gene="smc"
                     /locus_tag="LP493_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HBL2133924.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            16733..17542
                     /locus_tag="LP493_001773"
     CDS             16733..17542
                     /locus_tag="LP493_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL2133925.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            17553..18551
                     /gene="ftsY"
                     /locus_tag="LP493_001774"
     CDS             17553..18551
                     /gene="ftsY"
                     /locus_tag="LP493_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HBL2133926.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            18738..21005
                     /gene="gshAB"
                     /locus_tag="LP493_001775"
     CDS             18738..21005
                     /gene="gshAB"
                     /locus_tag="LP493_001775"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HBL2133927.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKKYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(21094..21546)
                     /locus_tag="LP493_001776"
     CDS             complement(21094..21546)
                     /locus_tag="LP493_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HBL2133928.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            21696..22646
                     /locus_tag="LP493_001777"
     CDS             21696..22646
                     /locus_tag="LP493_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBL2133929.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            22639..23598
                     /locus_tag="LP493_001778"
     CDS             22639..23598
                     /locus_tag="LP493_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBL2133930.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            23595..24350
                     /locus_tag="LP493_001779"
     CDS             23595..24350
                     /locus_tag="LP493_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2133931.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            24373..25326
                     /locus_tag="LP493_001780"
     CDS             24373..25326
                     /locus_tag="LP493_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL2133932.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(25970..26266)
                     /locus_tag="LP493_001781"
     CDS             complement(25970..26266)
                     /locus_tag="LP493_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HBL2133933.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            26621..26977
                     /locus_tag="LP493_001782"
     CDS             26621..26977
                     /locus_tag="LP493_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBL2133934.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            26987..27886
                     /locus_tag="LP493_001783"
     CDS             26987..27886
                     /locus_tag="LP493_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HBL2133935.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            28403..29134
                     /locus_tag="LP493_001784"
     CDS             28403..29134
                     /locus_tag="LP493_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBL2133936.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            29279..31306
                     /locus_tag="LP493_001785"
     CDS             29279..31306
                     /locus_tag="LP493_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBL2133937.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRINIPVENQRIGTFEGKLSWILADVPGN"
     gene            31414..32511
                     /locus_tag="LP493_001786"
     CDS             31414..32511
                     /locus_tag="LP493_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBL2133938.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            32818..>33263
                     /locus_tag="LP493_001787"
     CDS             32818..>33263
                     /locus_tag="LP493_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2133939.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRK"
BASE COUNT        11138 a         5762 c         7123 g         9240 t
ORIGIN      
        1 aaaaaccgtt cactatctga acggtccaag tatcattcaa ttaaacgcgt tcaacttttc
       61 ctgatttcaa agcacgagtt gacacccaaa cttttttagg ttttccgtcg accataacgc
      121 gaactttttg taagttaggt ttaacagtac gttttgttga gttcatagcg tgtgaacggt
      181 tgtttccact ttttgtcttg cgacctgtaa agtaacaaac ttttgccatg gtaatttcct
      241 cctttgcctt gatttggagc aatagaataa ttcagctcat accagactaa catatcatat
      301 agaatggaaa tttgcaagta cattttcata gatacaattg acaattgaga agaataattg
      361 taaattaaac aaggttatac ctgaaatttt gcaaggtttt tgagtacttt gggtaactgc
      421 cttttatttc aagttgcgct atgataaaat atgatagaag aaaaatggga gttttttacc
      481 cgttaaggag gctcattcat ggctgtaaaa attcaaacgt cagctggaac cattgaaatt
      541 accaatgatg taattgcaac agttgttggt ggcgccgcga cagatgtgtt cggtgttgta
      601 ggaatggcca gcaaaaatca aattaaagat aatattactg agattttgcg taaagaaaat
      661 tactcaagag gagtagttgt ccgccaagaa gataatggta ttgctgtaga tgtttatacg
      721 attatcagct atggtacgaa aatctctgaa gtttcccgca acgtccaaga aaaagtgaaa
      781 tacaatctag aggcattatt aggcgtaact gccaattcag ttaatgtctt tgtacaaggt
      841 gttcgtgtac tgccagacta ggcaggagac tggctggtaa ctcagcagtc gatctgaagg
      901 aggattatct aggtgagtgt aacagaaata agtgcaagcc agttccagga aatggtccag
      961 gcaggtgcga atcgtctgca agtaaatgca gaatacgtca attcattaaa tgtattccct
     1021 gtgccagatg gcgatacggg aacaaatatg aatctatcta tgactagtgg agctaaggca
     1081 gtagtagatt caacctcaga aaaagtagga gaattagcag caatgctttc aaaaggattg
     1141 ctgatgggtg cgcgcggaaa ttccggcgtt attttgtctc aattgtttcg tggattttct
     1201 aagcaaattc cagatgttgt ctcattaaat gcttccgatc ttgctgcagc cttcactcat
     1261 ggagttgaaa ctgcgtataa agcagtaatg aaaccagtag aaggaacgat tttgacagta
     1321 gctagagaag cagcgaaagc tggagaaaag aaagcaaaaa gtactgatga tgtcgttgaa
     1381 gtaatgacag ctgttgtaaa aggggcaaag cgtgctttag ctaaaactcc agacttgctt
     1441 ccagtcctaa aagaagtcgg tgtcgtagac agtggagggc aaggactgct gtttgtttat
     1501 gagggctttt taagtgcatt gaatggagaa ttccaagcgg atgaaacata tgaaccttct
     1561 ccagcagaaa tggatgatat ggtcaatgca gaacatcatc gcagtgtcca aggtcaaatg
     1621 gcgacagaag atatccattt tggttactgt acagaaatca tggtaaaaat cggagaagga
     1681 cctacagtcg atagtacatt cgattacgaa gaattccgta actatttaga tggtatagga
     1741 gattctttac ttgtggtcaa tgatgacgag atcatcaaag tccacgtgca tacagaaaac
     1801 ccaggagaag tcttgaatta tggacaaaaa ttcggttcat tagtcaaaat caaagtcgac
     1861 aacatgcgct tgcagcatga gacgattttg gaacacgatg aagaagtgaa cgagtttgcg
     1921 aaaaaagaaa caccacgtat cccgtatggt atcgtagcga tcgctgctgg taaaggcgtc
     1981 caagagctgt ttgaaagttt aggcgctaat tatgttatca gtggtgggca aacaatgaat
     2041 ccaagtacgg aagacattgt taaagcgatt caagaagtaa acgcagataa agtgattgtc
     2101 ttgccaaaca ataagaacat cttcatggca gctgatcaag cagcagaagt agcagatatc
     2161 ccagtagcag ttgttccttc aagaacgatt tcccaaggat tgacagctat gctttcattc
     2221 aatgatcaag cttctttaga agaaaacaaa gaaacgatga cagaaatgtt gtctagcgtt
     2281 gtgagcggtc aagtcactca cgcgatcaga gatacctcaa ttgacggtgt agagatcaaa
     2341 gaaggagact ttttgggcat gatcgatgga aaaatcctga tctctaaccc agatatcaca
     2401 gcaacagcgt taagtacact agaacaaatg atcaatgagg acacagagat cgtaacgatc
     2461 ttggcaggtg atgaaggaac agttgaacaa gcaaatgaat ttgctgagaa actaacagaa
     2521 aaacatcctg atttggaaat cgagatccac caaggagatc agcctgtcta tccttatcta
     2581 ttttctgctg aataatttct gtgtcagaat atctttctaa cacagtattc attcataaaa
     2641 ggccttcggt tagtgatcag gtatgatcgc tgaccaagtc ctttttttgt taagggaggg
     2701 aggaaaaatt tatgcgttct ttagatgatc caatcactat gctggcagga gtcggagaaa
     2761 aaagagcagc tagtcttgcc agcttgggca tccaaacgat tgaagactta ctgacttatt
     2821 atcctttccg ctacgaagat attcaggaaa gaaatctaaa cgagatccaa gatcaagaaa
     2881 aggttacttt gaaaggaatc gtagtctcgc ctcctgtgat gaatcgattt ggttataaaa
     2941 aaagccgatt gcaatttcgt atgatgcaag aacatgatgt gttcaacgtt tcttttttta
     3001 atcaacctta tctaaaagaa aaagtcattt tatcggagga aatcgccgta tacggtaaat
     3061 gggatgcaaa gcgtaaagca ttgaacggga tgaagatttt aggttctcaa acaatggatg
     3121 acttttcgcc gatatatcac gtcaacaaat caattcgtca aacgacatta gttgatctaa
     3181 tcaaaaaagg gtttcaagaa tacggcacat tgattgaaga aaatctgcca aacaaccttg
     3241 tggagaaata tcgactgctt gaccgagctt ctgctgtaag aagtatgcat tttccaaaag
     3301 accacgaaga aaaccatcaa gccaaacgac gtgtcgtttt tgaagagttc tttttatttc
     3361 aaatgcgtct tcaaggattg aaaaaagcag aaaaagcaga aacgaatggt ttggagatcc
     3421 tttatgatgt ccaaaaattg aaagaattta ctcaaaagct accttttgaa ctgacaaatg
     3481 cacaaaaacg tgtaacgaat gaaatctgtc gggatcttcg cagtccgcag catatgcagc
     3541 gacttttgca gggagatgta ggtagcggaa aaacagtggt tgccgcgatt gcgttatacg
     3601 ctaccgttac agcaggtttc caaggtgcgt tgatggtgcc tacagaaatc ttggcacaac
     3661 aacatatgga aagcttgcaa cagctgtttg atcccaatga agtaaccatc gcattgctta
     3721 cggggtcaac gaaagcaaaa gaacgtcgtg agctccttga aaaactagag caaggggaaa
     3781 ttaacatcgt gatcggcaca catgcattga tccaagatgg agtcgaattt cagaatttag
     3841 gtctagttat tacggatgag cagcaccgtt ttggcgtgaa ccagcggaaa gtacttcgtg
     3901 aaaaaggctg gcgaccagat gtcttattta tgacagcgac tccgattcct agaacattag
     3961 ctattacagc atatggtgag atggatgtat ctatcattga tgaacttcca gctggacgta
     4021 tcccgatcga aacacgctgg gtaagaacac ctcaattgga cagtgtactg gattggacga
     4081 aaaaagaact ggcaagagga catcaaatgt atgtcatctg tccgctgatt gaagaatcag
     4141 aagcattaga tgtaaaaaat gcagtggaaa tctatgaaaa acttcgtgaa ctatttgcac
     4201 caaaatatga agttggcttg ttacatggta aaatgaagaa tcaggaaaaa gaagtaatca
     4261 tggaagcctt caaagacaac cagatgcaga tattagtttc gactactgta attgaagtag
     4321 gggtaaacgt gccgaacgcg accgtcatgc tgatcatgga tgcggatcga tttggattgg
     4381 cacagctgca tcaacttcgt ggacgtgttg gacgcggaag tgatgcttcc tactgtatct
     4441 tagttgctaa tcctaaaaat gaactaggtg tggaacggat gaaaatcatg acagagacca
     4501 ccaatggttt tgtactaagc gaaaaagatc tggaattacg tggtcctggt gaagtatttg
     4561 gcttccgtca atctggtctg cctcaatttg cgattgctga cttggtgacg gatggaaatg
     4621 ttttggaggt agccagagaa gaggctgcag ccctttggca gataaaggat tggcagatgc
     4681 ttcctgagta tcagccttta gcgcaaagcc tccaaataga aaatcaggat aatcgttatt
     4741 tcgattagca gactgtgcta tactttatac tgatgacgga aaaaggagtg gaaacaatga
     4801 aaattgccgt agatgcaatg ggcggagatc acgcacctca agcaattgta gaaggcgtgg
     4861 ctttagcgca gcaagatttt ccagaagtag aattcttact ttacggaaaa gaagcagaaa
     4921 tcaagaaata cttaacaaat gaaaaaaaca tcacgattat ccatacagac gaaaaaatca
     4981 atagtgatga tgagccagta aaagcaattc gacgaaaaaa gactgcatca atggtccttg
     5041 ctgcacaagc agtgaaaaac ggtgaagcag atgctgtatt ttcagcaggg aatacaggcg
     5101 cgctactagc agcagggttg ttcatcgtag gacgtatcaa aaatatcgaa cgccctggct
     5161 tgatgtctac cttgccagta gtagggaaag aaggtgccgg tttcgatatg ctggatcttg
     5221 gcgctaacgc agaaaacaaa ccagaacatt tgttgcaata cggtatttta ggttcttttt
     5281 atgcacgtaa agtccgaggt atcggacgtc ctcgtgtcgc actcttaaac aacggaacag
     5341 aagcaacaaa aggtagtgaa gtgacgaaaa aagcctatga actccttcag aatgaaacaa
     5401 gcttgaattt tattggaaac gtagaagctc gtgagctact caatggtgtg gctgatgtag
     5461 tggtcacaga tggatttaca ggcaacgctg ttttgaaatc tattgaagga acagcaatga
     5521 atatgatgaa tctattaaaa tctgctattc taaatgaagg gatcaaagga aaaatgggcg
     5581 ctatgctttt aaaagacggc ttacgttctt tgaaagcaga aatggattat tccaaacatg
     5641 gcggtgccgt tttgtttggc ttgaaagcac cagtcattaa aactcatgga gcaacaggcc
     5701 ccgatgctgt tcgctatacg atccgccaaa tccacacaat gcttgagaca gatgtagttg
     5761 gacaattagt cgaacaattt gaaaaaagcg aagaatagta tttggatatc tgaagcaatc
     5821 cgttccattg aaaaaaaggt ggacattcct gaaaaatgcc agtaaaatta gccatggtgt
     5881 aggtaattga caagtgtatg attcttggag gtgaaaaagt tgactcgcga agaagtattt
     5941 aacaaagtag cgaaaattat ttcaaatcat tttgagatag ataccgataa agtgacggat
     6001 gaattgaaca tcaaagatga tttaaaagct gattcaatta gtattatgga attcgtttta
     6061 gagcttgaag atgaattcgg tacggaaatt tcagatgaag acgctgaaca aattgaaaca
     6121 gtcggtggcg cagtagatta tatcagcagc catcttaaat aatttcaaat aaaagcaaag
     6181 aaggataaaa agctgcatac agctttttat ccttcttttt ttaatctttt tgacacgtaa
     6241 aagtcatttt tctgataatt ctggcgataa acagaaatta tgttgcaaag taaagcgatt
     6301 ttctatataa ttattaataa ttcattacac aaagataaga ataacctttg ttataaaacg
     6361 ctttattctg tgtaatgtcc ttttttatta agaaaaactt ccatttagga agcagagagg
     6421 ggtattcgat tgtccgataa ccaattatta gaagttcaga acctacatac aggattccga
     6481 ctcaaagatg actattacga tgcagtagat gacgtttcat ttactttaga caaaaacgag
     6541 attttagcaa tcgttgggga atctgggtgc gggaaaagta ccttggctac tacgattatg
     6601 ggattacttg atcctaataa cacaaaaatt acaggtgaga ttttatataa cgatctgaat
     6661 ttaatcgacc tgaacgaaac gctctataat aaaatccgcg gaaatgatat cggaatgatt
     6721 ttccaagatc cgttgtctgc attaaatcct ctcatgagaa tcgaagacca gatcaaagaa
     6781 ggactttcct atcacacaaa gatgaatgca gaacagcgtc aagctcgtgc actagaattg
     6841 ctagaacaag tagggattcc taatcctgcg agagttggac gccaatatcc ccatgaacta
     6901 tcaggcggta tgagacaacg tgtcatcatc gcaatcgcaa tcgcctgcaa acctccaatc
     6961 gtcattgcag atgaaccgac gacagcccta gatgtaacca tccaagcaca gattcttgat
     7021 ttactgaaag accttcagga agaaacaaaa acagggatca tcttgatcac tcatgactta
     7081 ggagtcgtag cagaaatggc tgatcgagtg gcagtgatgt atggcggaca gttcgttgaa
     7141 gtagcaggtg taaaagaact gtttgatcat cctaagcatc cttatacacg ctctttactg
     7201 aactctatac cacaagaagg aaatcatgat gcagaactcc atgtgatcga aggtgtcgtt
     7261 ccttctctga aaaacatgcc tcgtaaaggt tgtcggtttg caccacgtat tccatggata
     7321 ccagcaagcg atcatgaaga agagcctatc cttcatgaag tcgcaccgaa ccacttggta
     7381 cgttgctcct gctataagca tttccacttt agagacgaaa aaggagaggt gtagatgaca
     7441 gaattaatca caatcaaaga cctgaaagtt cattacccta ttcgcagtgg attcttcaat
     7501 cgagtaacgg atcatgtata tgctgtagat ggtgtggatt ttattatcga aaaaggaaag
     7561 acatatggtt tagtgggaga gtctggctct ggaaaatcta ctacgggaaa agccgttgtg
     7621 ggattagaaa aggtaacagc cggacaaatc atgtatgaag gaaaagatgt aacgaagcga
     7681 agcaaccgca aaaaaatggg ttataacaag gatgtgcaga tgatcttcca agattcaatg
     7741 tccagtttga atcctaaaaa gcgagtgttg gatatcattg ctgaacccat ccgaaatttt
     7801 gaacggttaa gcgatcaaga agaaaagaaa aaggtaaaag gactgctaga tatcgttggg
     7861 atgccggaag atgcgctata taaatatcct catgaatttt caggcggaca acgtcaacgt
     7921 ctaggagtag cccgtgctgt tgctaccaat ccaaaactga tcgtagccga tgaacctgta
     7981 tctgctctgg atctatctgt tcaagcgcaa gtattgaatt tcatgaaacg aatccagcaa
     8041 gaatacggcc tcagctattt attcatttca catgatttag gtgtagtaaa acacatgtgc
     8101 gacaatatcg caattatgta caaaggtcga tttgtagaaa tcggtacaag agaagacatt
     8161 tataatgacc cgcgacatat ctatacgaaa cgtctgcttt cagctattcc gcaaatcgat
     8221 gtagaaaata gggaaagcca caaagaaaat cgacgaagag tagaacaaga gtatatccaa
     8281 aaccaaaaag aatactatga tgcgactggt cgagtctacg atttgcgtac gatcacaact
     8341 acacacaaag tggcgttgaa agatggaggt gcaagctaat gtggaaaacg attctgcgac
     8401 gtgttttatt gatgatcccg caagttatta ttttaagtgt tctgatcttc ttattagccc
     8461 aagcgatgcc gggggatcca tttaccggtt tgatcaatcc aaatcaggat ccggcagtga
     8521 tcgaacagat gcgacaagca gctggcttga atgacccatg gtatgtccag tacttccgtt
     8581 ggatcggaaa tgctttgcaa ggcgattttg gtcaaagttt cttatacaaa cgctctgttg
     8641 ctgacttgat cggcgaacgg atcatcaaca ctttatatct atcgatcttg acagttgtcc
     8701 ttacttattt gattgctgtg cctctgggga tgcttgctgg ccggtatcaa aattcaatct
     8761 tggataagat tgtcgtaatc tacaacttct ttagttttgc tgttccttta tttatcttcg
     8821 gcttgatcat gctatttgtt tttggttatc gtttaggctg gttcccaaca agtggatcac
     8881 aaacactagg tttgcaaggt ggatttatca ctcaatggat agaccgtttg aaatatattc
     8941 tgttaccatc aattacccaa gcatttttgg cgactgccgt cacaatccaa tatctgcgaa
     9001 gtgaagtaat cgattcgaaa tcgctcgatt ttgtcagaac agcccgttcc aaaggggtac
     9061 cgacgaataa agtattcagt cgacatattt tccgaaatgc agcgttgccg atggcttctc
     9121 aaatggggta tgaaatcact tcgttgattg ctggttctgt agttatcgaa aagatttttg
     9181 gttatccggg agtcggaaaa ctatttattg attccatcgg ccaacgggac tataccgtga
     9241 tcacatcctt agtattgatt ttaggaatcg cgacgctagt ggggacatta ctttcagata
     9301 tcatcatgag tatcgttgac ccgcgtattc ggattcaata aaaccaatca gaaaggagaa
     9361 tggatcgatg agtgaaaaaa acaatacagc agttcaagaa agtattcctc ctatggggat
     9421 acgaatgatt gctcgagaat ttaaaaaaga taaaattgct attttttcat taggtttgct
     9481 agtggtttta ttattagtga tctttatcgg tgcgatgctg accgatcaag acaaagtgat
     9541 gtatgttagt atcttcgaca aatacgctgc accaggaaca gtttcgacac aaggacaaaa
     9601 gttcattctg ggagcagatg aaggcggacg tgatgtatta ggacaattga tcataggtgc
     9661 tagaaactct gttacgatcg gatttgcgat cacgatcctt acttcgatca tcggggttgg
     9721 attagggatc atctctggct actacggagg gatcattgac aacatcttga tgcggatcgt
     9781 tgattttatc atgattctac cgatcatgct gatcattatc gtcttcgtat cgattatttc
     9841 cagatacaat gtctggtcct ttatattcat catgagtgca ttttattggg tagctaaagc
     9901 ccgattattc cgaagcaaga cattatctga agcaagaaga gattatgtca gtgcctcaaa
     9961 aacaatggga accaatgatt ttaaaatcat gttccgcgaa atcatgccga atctaagttc
    10021 attaatcatt actaatttga cgatgaactt tgcggcaaac atcggtatcg agacaacttt
    10081 gactttctta ggtttcggct tgccggcaaa tgtacctagt ttaggtacat tgatcggtta
    10141 tgcaagtaac ggagaagtct tagtgaatcg gcaatggatc tggttacccg catcaatcct
    10201 tattttagtt ttgatgttga gtatcaatta tgttggacaa gcattcaagc gttctgcaga
    10261 tgcgcgccaa cggttaggct agtatagaag cgaaggggga aataggaatg aagaaaacga
    10321 tttttggatt tgcagcgctg atgtctgctg tcgttcttgc agcatgcggg ggcggaggta
    10381 cagatacctc tggaaacaac tctggaggca acggcaataa caaagaggaa ttaacttttc
    10441 caattgcaac aaaaaataat gatgatgcaa tcgaagacgg cgaattagaa gctgcggtcg
    10501 caacggacag tcagtttaaa ggattgttcc agtgggagtt ttaccaagat tcatatgatg
    10561 cagcttttat ggctccttct catgaaccgc tatttgcaaa cgatgacgat ttcagaatca
    10621 cagacgacgg agctgcaacg cttgatctag atgaagatac gaaaaaagcg acaatcaaag
    10681 taaaagacaa cgtcaaatgg tcagatggtg aagatgtaac ggcggacgat gtgattttcc
    10741 cttacgaaat cattgggaat aaagattaca ctggtatccg ttatgacgac actttccgta
    10801 acatcgtagg tatggaagaa tatcatgatg gaagtgccga cacaatctcc ggaatcaaaa
    10861 aaatagacga caaaacagtt gaaatcgaat ataaagaagt aaacccaagc atgcttcaat
    10921 cgggtggtgg tatctggtca tatgcagcac caaaacatac gttagaaggt gtagcaatca
    10981 aagatatgga atcaagcgat caagtacgta aaaatccagt gacttttggc ccttattaca
    11041 tgagtaatat cgttgcagga gaatcagtag aatacttgcc aaacgagcac tactggaatg
    11101 gtacgcctaa attgaaaaag atcacgatga aatctgtacc gatggcaagt gcaactgaag
    11161 cattgaactc taaattatat gatatgattt tccaaatgcc aacagatact tacgatacct
    11221 ataaagaaat tgctggctat acaaacttag gccgtgaaca aacttcttat acttatctag
    11281 gattcaagtt aggtaaatgg aatgcagata caaagagtgt ggaatacaat ccagattcaa
    11341 aaatggctga taaatcatta cgtcaagcaa tgggctatgc attagataat aatgcagtag
    11401 gtgaacgttt ctatgcaggt ttgagaagca atgcgacttc attgattcct ccagtattcc
    11461 agtcatacca tgatgatgag atgaaaggat tcacacaaga tctagacaaa gcgaaaaaac
    11521 tattagatga tgctggctac aaagatgtgg atgacgatgg tttaagagaa gacaaagatg
    11581 gaaataaact aacaatcaac tttgcttcga tgtccggtgg ggaaacagcg caaccattgg
    11641 cagattacta tatccaacaa tggaaagaaa ttggtttgga tgtccaatac acaacaggtc
    11701 gtctgatcga attcaattct ttctatgata aattagaaaa cgatgatcct gaaattgatg
    11761 tttaccaagc tgcttggaat acaggaactg atccaaatcc aagtggacta tggggaccaa
    11821 atgctgcgtt caactacact cgttatgaat cagaagaaaa tacaaaattg atcaacgata
    11881 tcagttcaag caaagcattt gatgaagagt accaaaaaga agcatatcaa aaatggcaac
    11941 aatatgcatt tgaagaagca tttgcgattc caacgttgtt ccgtaatgaa gtattgccag
    12001 tcaacgaccg tgtcaaagac tgggattggt cttatgatgt accaaaccca tgggcaaatg
    12061 tttctgttac agcagattca cgttcataat cactaaaaat gaccgaaaaa gggcgatgtc
    12121 ctttttcggt tttttgatat ttttctgttt atttctctaa tattcaggtc aaggcgctga
    12181 tttcatgact tctccaataa acggtgttca aagtccagtt tctcggtatt aagtcaaatt
    12241 tatgcaaaaa tatggaaagc cattttcaca aaattttttc ttcatactcg aaactaaacg
    12301 aatttttcac aacttctcgt caatcactag gattattaaa gctttactta ccttttgacc
    12361 gaaccatttc aaatttgaca aaaaaccagt ataataagga agtatcgaaa aaatatccat
    12421 aaaaggaatg tggaaaatgg acaaccagct gacaaaagaa ctaaaagaaa actataacat
    12481 cgtttttcac gatctaaatt tgcttgaaca agcttttacc cattcatcct atgtgaatga
    12541 gcatcgcaat ctgcaattat cggataatga gcgacttgaa tttttaggag atgccgtttt
    12601 agaactgatg gtttctcagt atttattccg tttatatcct catttgccag aaggaaaatt
    12661 gacaaaaaca cgagctgcga tcgttcgcga agacagcttg tcgaaatttg ccaaagaatg
    12721 tcactttgat caatatgttt tgttgggcaa gggagaagag aattcaggag gacgtacgcg
    12781 accagcattg ctttgcgacc tattcgaagc ttttttaggc gcgttatatc ttgaccaggg
    12841 attcgacacg acccatgcat tcatcgaaaa agtgattttt cctaaagtca aagcaggtgc
    12901 tttttcacat gagatggatc ataaaacaaa actacaagaa gtcttgcaaa aatcaggtga
    12961 tgtatcaatc gaataccgat tgatcaatga agaaggtcca gctcatgaac gagtattttg
    13021 gatcgaagtt tatgtagatg atcaattgat tggcactgga caagggaaat cgaaaaaatt
    13081 agcagaacaa gctgcggcgg aaaatgcatt ggcagcactg taaaagtaag tgagggaaag
    13141 ctttgtattt gaaacgaatt gaaatagccg gttttaaatc atttgcagac aagacagtca
    13201 ttgattttga aaatagcgtc acagcagtgg ttggaccaaa tggcagcgga aaaagcaata
    13261 ttacagaggc tatccgctgg gtattaggag aacaatctgc taaaagtctg cgaggcggaa
    13321 aaatgccgga tatcatcttt gccggttccg atacccgtaa gcagctgaat attgcagaag
    13381 tcacagtgat tttagacaat agtgatcatt atctgccatt ggagtacaat gagatcagtg
    13441 taacccgccg ttatcgacgg actggggaaa gcgagttttt catcaataaa caaagctgca
    13501 gattaaaaga tatccaagaa ttgttcttag attctggatt aggaaaagaa tcgttctcaa
    13561 tcatttctca aggaaaagta gaagcgattt tcagtagtaa accggaagac cgtcgtggga
    13621 tctttgaaga agcagctggt gtcttgaaat acaagcagcg gaaaaagaaa gcagaacaga
    13681 agctttttga aacagaagac aacctcagcc gcgtccaaga catcatccac gaattggaag
    13741 aacagttaac tcctttggcc gcccagagtg aggcagcaaa ggagttttta cggctaaaag
    13801 aaacactgac tcaaaccgat gtctctttga tggttgctga aatcaagaca gcaaaaaaag
    13861 attgggacaa caaacaagca cagcttgcga aattcaatct agaattaggc aaactatctg
    13921 agtcgatcca agaacaagaa tccattttgg cgaagcagcg taaagaaaat gcgcaagccg
    13981 atcgtctgat cgaaaaaaat cagcaagtat tattagatct ttcggaaaaa ctgaagcaga
    14041 cagaaggaca aaaagatgtt ttgcaggagc ggacaaagca tacacaaaaa agctcgcaag
    14101 aatatcaaac ttcattagca gaagcacaaa aaaaggttaa acattttgaa aagcttcaag
    14161 aaagcttgat gaaagcagca gcagaaaaag aaacagagat ccaaaaagct gaagcaaatc
    14221 tcataaaaac acagcaagaa ttagaaaaat accaaaaatc aacgaaagaa ttattggcag
    14281 aattaagaga tcaatatgtt gatttgatgc aagaacaagc agctgtagga aacgaactga
    14341 agtatctaga acgtcaatat atacaagaaa cagcaaaaag caagcagacg ttagccaagc
    14401 aatcggaagt agaagcatca gtagaccgat tgatcttaca aaaagaagaa ttgacacaaa
    14461 agcaggcgca gctaaaatca tctttaactg aaacaaaaga gaagttagaa atgatccaac
    14521 aaaacgggaa aaagttccaa gaagcattag caaaagaaca gcctaaaatg tatcaattaa
    14581 tgaatcaagt ccagcagcta cgtgctcgta agaaaagcct tcaagaaatc caagaaaact
    14641 attttggttt ttaccaaggg gttcgattgg tcttgcagca taaacagcag ctttcgggta
    14701 ttgtcggagc agtggctgaa ctgatcgatg ttcctgcaga tttcacgtta gctatcgaag
    14761 cagctttagg tggggcagcc cagcatgtca tcgttgaaaa tgaaaaagat gctcggcaag
    14821 ccatcacgta tttgaaacag caaagaggag gaagagcaac attccttcca ctgacgacaa
    14881 tcaaaccaag acaattaccg gctcatatat tgacacaagc agcagctgta gaagggttta
    14941 tagggattgc cagtgaacaa gtcagttatc ccgatcaaat ccaaactgtg gttcaaaacc
    15001 tgctaggaac gatcctttta gccaaagact taactagtgc caatgcaatc gcgcaaacga
    15061 tccgctatca atatcgagtg gtttccttag aaggtgatgt gatgaatgcc ggaggatcca
    15121 tgacaggtgg agcgaataaa cgaggaaacc aaggcagttt gtttgtacaa aatcaagaat
    15181 tgaaacagtt gactagtgaa tttgaagaag cagataaaca actccaagca caagaaaaaa
    15241 aagttcagga gctgcaacaa gaaacagctc gtttagccga agaacaagaa gttttgcgta
    15301 cacgaggcga acaattacgt tttgaagaac aagaagcgac aaatcagcta caaaacatca
    15361 taaatgaact tgaacgtttt gaaaaagaaa agcaaatctc aacttttgag acacgtgaac
    15421 tgcagcagtt tatcgaagat tacgaaaagc aaacgaacga attgaaagac aaacaaacag
    15481 atcttgaatc gcaacgacaa aaaatcgacg aagaaatcaa atcgttaagt caagaaagcg
    15541 accagatgga agccagaaga gcacaagtac aaagtcaaaa agcacaagaa caagcagatc
    15601 ttgctgtctt gaaagagcag tttaatcatc tgcagatcca gctccgcggt gcccgagtcc
    15661 aaaaagcaga ggcaaccgaa cgtcaagaag cgatagaaaa gcagttggcg acattgacag
    15721 cagacttttc tgatcatgaa gtcacagaag aaagtttgga aaaacaaatt aacgaattat
    15781 ctgctcagcg agaaacatta aaagccgagt tggcaaaagc caaagagcag cgagatagaa
    15841 ggcaaaagga gatcgataag cttgaagcag tcttggcaga gcgtaatcgt gagcaaaaag
    15901 cacgactgtc ggaacaatcc aaattagaag tccaaaaaga ccgagctgaa atgattttag
    15961 ataatcattt gacctatctg cagtcagaat atcagctgac atttgagaaa gcttcccaag
    16021 actatcaaga aacaaccgat atcgaagaca gtagaacaaa ggtttcatcc ttaaaagaac
    16081 agattgaaaa actgggacca gtaaacttaa attcaatcga acaatacgaa caagtcagtg
    16141 aaagacatac attcttagca acacagcgag atgatctgtt agcagcgaaa aaccaattgt
    16201 ttgaaacgat ggatgagatg gatgatgaag tgcggacaag attcaaagaa gtatttgaag
    16261 ctatccgtca agaattcaaa attgtctttc caaatatgtt tggcggcggt aaagctgaat
    16321 tagtactgac ggaaccaact gatttgctga aaacaggtat tgagattgaa gtacaacctc
    16381 ctggcaaaaa actgcaaagt ctaagtttgc tttctggagg agaacgagca cttacagcca
    16441 tcgcgttgct cttttccatt atccgtgtct gtcctgttcc gttttgtatc ttagatgagg
    16501 tagaagcagc gttagatgaa gccaacgtga aacgttttgg tcgttacttg agcgatttcc
    16561 aagatgacac acaatttatc gtagtcacac accgcaaagg aacgatggtc gcagcagatg
    16621 tactgtacgg agtgacgatg caggaatccg gtgtatcaaa aatcgtttct gtacggatgg
    16681 aagatatcaa tgaagaggcg aaaatcaacg aaacgaaagt gtaggaacga aaatgatcaa
    16741 attagtagca atcgatttgg acggtacatt attaaatgaa caaaagctga tttcagatga
    16801 gaataaacaa gcattagcac aagcaaaaca gcaaggggtc aagatcgttc tatgtacagg
    16861 acgcccctta gctgcgatgg cgcattatct gcaagaatta ggactggtag atgaaggtga
    16921 ctacagcatc actttcaacg gcggtttggt acaaaaaaat gatactggtg aaatcatgga
    16981 aaagaaagtg atggaagtat cagatatcca acgcttatac aaactggctc agcaattgga
    17041 tctgccacta gatgttttgt ctgacaatgt ggttttacag ctgcctagtg ccccaaggaa
    17101 gcaatccttg tacaatgtgt tgaataagct gctgcaattc caaccagcgg atataagcga
    17161 tattacagat gaatttgtgc ttaataaggc agtaatcgct tatgaccaag aagaattaga
    17221 tcctaaaatc aaagaaatac cagcagaatt ccatgaaatg tatgagatca tcaaaacaag
    17281 aagtatgctt ttggaattta tgccaaaagg tgttacaaaa gcttatggta tttctttatt
    17341 ggcaaaagat cttggtttga aacaagaaga aatcatggcg atcggtgatg aggaaaatga
    17401 tttaccgatg atccaatatg ctggactagg cgtagcgatg gagaatgctg tgcctttcgt
    17461 caaagaagca gcagatttcg tgacagccag caatgaagaa aatggcgtag ccaaagtgat
    17521 ccaaaaattt gtattagagt agggggagtc aaatgggatt ttttgataaa atcaagcgtg
    17581 cttttactgg cgaagagaaa acagaagaag ttgaagtaca ggagaagtac gacaagggtt
    17641 tagaaaagac gcgtaaaaca tttggtgaac ggatgaatga gttgtttgcc aattttcgaa
    17701 cagtcgatga agactttttt gaagaattag aagaaacact tatcggtgca gatgtaggtt
    17761 ttgaaacagc gatacgaatc accgaagcat tacgtcaaga agtgaaactc agaaatgcga
    17821 aaaaatcggc agaagtccaa aatgcgatca tcgagaaact tgtggatctc tatgaagcgg
    17881 aaggaatcaa tgaagtaaat gaactaaata tccaagaaga cggactaaca gttattttgt
    17941 ttgtcggtgt taatggtgta gggaaaacaa caagtattgg taaacttgcc catcagttca
    18001 aaaacgaagg taaaaaagta ttgatggcag cagcagatac cttccgcgct ggagcaatcg
    18061 accagttagt tgtctggggc gaacgcgctg gtgttgaagt tgttcgtggc aatgcaggag
    18121 gcgatccagc agctgtcgta ttcgatgctt tggaaagagc aaagacagag caggcagatg
    18181 ttttactagt tgatactgca ggccgactgc aaaataaagt gaacttgatg aacgaattag
    18241 aaaaaataaa acgagtaatc cagcgggaat taccagaagc accccaagaa acacttcttg
    18301 tattagatgc aaccactggt caaaacgcga tggttcaagc aaaacaattc aaagaaacaa
    18361 cagatgtgac cggtcttgtt ttgacaaaat tagatggtac agcaaagggc ggtatcgtac
    18421 ttgctatccg taatgaattg catttaccag tgaaattggt cggtcttggt gaaggaatcg
    18481 atgacttgga gccgtttgat ccaaatgatt ttgtcgttgg attgttcaaa ggattactaa
    18541 aagaagaata acccatgtct aaaaagcagg agctgtgaca aaagttgcag ctccttgttt
    18601 gaatgattgt ttttaacata gctgtgtttt tgatgccttc atttttatac ttatttgtaa
    18661 gcggttctca aacaatttcg ttctttttct tagacttttt gattataatt agattcatat
    18721 gaattggagg tcacttaatg atgaatttta agcaattatt attgcatgtc aatgcgcgcc
    18781 cttttatcga ccaagctcga tttggtatag aacgggaagg acagcgggtt gatcttgcag
    18841 gaaatctagc aaaaaccgat catccagcaa tctttggcga tcgatcctat cacccctata
    18901 tccaaacaga ttttagcgaa acacaaacag agatgatcac ccctgttacc gattctattc
    18961 ccgaattatt tcagtatctc gctgctgttt atgatgtgac tgctcgttct ataccgaaag
    19021 aagagatgat ctggccatta agtatgccac ctgccttacc ggaaaaagac gaagagatca
    19081 ttattgcaaa attaaaaaat ttcgaagatg tcttgtatcg acgttattta gcaaaaaaat
    19141 acgggaagcg aaaacagatg gtaagcggta ttcatttcaa ttttgaattt ggcgatgagt
    19201 tgctaagaac attgttcagc catcaggaag aatttcaaga tttttccgaa ttcaaaacag
    19261 aactttattt gaaaacagcg agaaacttta tgcgctatcg ctggatgatc acttatttat
    19321 tcggtgcttc accaatgagt gagaagaact actttttaga tgaatcacat ccgcaagaac
    19381 ctgttcgcag tattcgcaac agtgcgctgg gctatacgaa tcatccaaat gtgaaagttt
    19441 cctatgcttc tatgaaacag tatttagcag atatcgagcg aatgatcgaa gaagggaaac
    19501 tttcggagga gaaagaattt tatacaccgc ttcgtttccg aggcggaaag aaagtcgcag
    19561 atttagcaac aacaggtgtt cgttatattg aattgcggaa tatcgatttg aatccttatg
    19621 caagattggg tatcaatcca gagcaagttc ggttcttaca attattcctg atgtacatgt
    19681 tatggacaga agaaaaagaa gactgtgacc aatgggtagc agaaggtacg actcgaaata
    19741 acaaagtagc actagaacaa ccatcagatc aaacagaatt tcatcaagaa ggtagagaaa
    19801 ttcttgaagg aatgaagcaa atgctggttg aattggattg gttggattct ctttatttag
    19861 tagaggaagc attgactcaa atggatcatc ctgaacaaac gttagcagcg aaactctatc
    19921 aagaagcaca gctatcgagt cagcaagaag ttgctgtggc attgggacat caatattata
    19981 aagaaagcca tgaacgtccc tatcagttgg ccggttttcg cgaaatggaa ctttctactc
    20041 agatatttat gttcgatgcc atccaaaaag gtgtccaagt caaagtatta gatgagtcgg
    20101 atcaattttt gcgtctgcaa ttccaagacc atgtagaata tgtgaaaaat gcaaacatga
    20161 caagtaagga cagctatatc gtcccactta tcatggaaaa caaaacagta acgaaaaaag
    20221 tcttaaaaga agctgggttc cgggtaccag gaggcgcaga attttcatcc atggaagaag
    20281 cggtaaaagc ttatccgaga tttgccgagc aggcatttgt gatcaaacct aaatcaacca
    20341 attacgggtt aggtatcacg attttcaagg aaggagctag tctggaagat tatcaagcag
    20401 gtttagccat tgcttttcgt gaagacagtt cggttttagt agaagaattt atgccgggaa
    20461 cggaatatcg tttctttgtg atcgacggag aagtccaagc catcatgttg cgagtccctg
    20521 ctaatgttat tggtgacagt atccgaacag tgaaagaact tgttgaagaa aaaaatagtg
    20581 accctttgcg tggaacgaat catcgtgcac ctttagaatt gatccaatta ggtgaattag
    20641 aacaattgat gttgaaagaa caagggttga cgatcgaatc agttccccaa gccaatcaaa
    20701 ttgtttatct aagggagaac tcaaatatca gtacaggtgg tgattcgatc gatatgactg
    20761 atgaattttc tgaagcttac aaaaaaatcg ccgtttctgc ggtagaagca ctaggagcta
    20821 agattagtgg tatcgatttg attataccag ataaagaaat cgatcctaca actgataaaa
    20881 aagcatatgg gatcatcgaa gcaaatttca atccagccat gcatatgcat gtttatcctt
    20941 ttgcaggaaa aggcagaaga ttgacgatga atgtattgaa attgttatat cctgaagtat
    21001 tttaaaagaa aaagcttttg acagattgtc ctatttgatg tcaatctgat caaaagcttt
    21061 ttttgcatgt aaaaatttat gtgttttttc gttttaaaat aaacgatccc agaagctttt
    21121 tttctttttt ggtttttctt tttcagctgg cgaagagttt tcttctgggt attttttttc
    21181 gatatcaatc acaggttcat ttactgcttc ttttgctgtt aagagcaatc cgaattcctc
    21241 aggatttgca gtgacgtaat cgttgactac agtgaaacgg ctattgtttt tcgttgctag
    21301 ctggatatat tggttttgga cagaaagggg tagagcccca ttcaagagta tggaagcatc
    21361 tggatgtttt ttgagttctt ttaaaaagtt ttctttgttt tttggttgga tcatttcagc
    21421 aacagtcata ctaagatagc agcgttccct gaatgtccct aaatatttat gctgttcttc
    21481 agggttcact aaaggtgtac cataaagtcc cttatccaaa tggcttttta catcatcttg
    21541 tgccataaaa aataccctcc ttcttctctt tgtctttctt acgattatag catattccca
    21601 ataataccta aaacatatga aaaagcggtt gcttttgttc aacgattcac ttaaaataag
    21661 aatgaaaatc attctcaatt agaaaggtgg attggatgcg ctacggacga ctagtagcat
    21721 tattagttat tttaagtagt atttcattgt tcatcggagt atcgaatgta caattgtcag
    21781 aactgctcca gttagatggg caaagcttac aaatcttgct agtgactcgt ttgccacgaa
    21841 cgatttgttt gatccttgtg ggagcgacca gtagtatttg tgggttgatc atgcaacatt
    21901 tgacccaaaa taaatttgtt tcaccaacga ctgcgggcac gatggatagt gcgcgtttag
    21961 gtattttagt ggctatgatt ttcctacctg gtgcatcctt gattgtccga tccttgacag
    22021 cattttgctt tgcttttgca ggaacattgc tttttttatc ccttacgcga ttgttcctcc
    22081 agaaaaatca attgatgctt ccgttgattg gagtcatgtt agggaatatc attggttcag
    22141 ttgctacttt ttttgcttat caattccagt tggtacaaaa tatgacttca tggcttcaag
    22201 ggaattttgc gactgtgata cgaggaaatt atgagttatt gtatgctgtt gttccattgt
    22261 tgctcttggt ttggctattt gcttaccgat ttacgatcat tggtctgggc gaatcgtttg
    22321 cagtaaatct gggaatagat taccagaaga tgcagttttt aggcattggc ttagtatcat
    22381 tggctagtgc agtcatgttg atcatggtag gaagcattcc ttttatcgga gtgatcattc
    22441 cgaatcttgt ctctagaata tatggagatc aagtgcacaa aacaattggc gtaactgctt
    22501 tagcaggtag tttgttctta gtattttgcg atcttgtcgc tcgcgtgttg atttttcctt
    22561 atgaaatacc agtcagtgtg atcgttggaa tcatcggtgg ggctatcttc ctttatcttc
    22621 tgataagggg acgacgatat gcttaaaaaa aagccatcta tttttattgg tatgcttgtt
    22681 cttgttttat ttgttacagg aatgtacttg acgatccata catatggaaa ctggcatttt
    22741 gcatgtgcat tgaggagtaa gaaaattttt gcatttatcc ttgtctcgct agctgtcagc
    22801 agtgccacaa tcagctttca gacaattacg cataaccagt ttttgactcc ttcagtattg
    22861 ggacttgagt cgttatatgt ccttgtccaa acggtccttt tcttctttat cggaggagtg
    22921 acgatgcttc agcagacagg tacagttttt ttcttattga acgttgggct gatggtcggg
    22981 ctgagtctat tgttattttt ctttcttttg aaaaaaatga gagcgaatct ttttttatta
    23041 ctgatgtcag ggatgatttt aggtacgctt tttggtagtg tcagtacctt tttacaagtc
    23101 atcatggatc cgaatgaata tgatttgctt caaggcagat tatttgcaag ctttggcaat
    23161 atccagagtc agtatctttt gcctgcttct ttgatcatta tcggctgctg gtacctgtta
    23221 tttcgatatc gacatgtgct agacgttttc catctcggaa atgaacaagc agtaaacctc
    23281 gggatagaca cagatcgttt tgaatttttg attttatgtt gtgtcagtct tttgacaggg
    23341 acatcaacgg ctcttgtggg tccagttact tttttagggt ttattgtcgc aaatatcagt
    23401 tatcgtgtct tttctactta tcgtcatggt cagctattta tcggaagctt tctggtagct
    23461 atgctgtttc tgacaggagg acagctcgca gtagagcaga ttttcggctg gaatacaaca
    23521 gtgagtgtcg tcgttgaatt tgtcggagga atttattttg tcacaaaatt gattcgcgaa
    23581 aggaagagta tcctatgatt gatttacaaa aggtcaataa actgtaccat ggaaaatcag
    23641 tggttaaaga tgtacagtta acgattcctg aaaagaagtt gactgctttt atcggtccaa
    23701 atggtgctgg aaagtcaacg gtgttgtcga tgatcagtcg tttgatacca aaagatacag
    23761 gtgaaatcta tttagaccat aacgaagtaa aggcttggaa atccaatgaa ttagccaaaa
    23821 aattatcgat cctacgacaa tcgaatgaaa taaatgtcca aatcaccgtg aaagaattag
    23881 tagaatttgg acgatttcct tatacgaaag gaaaattgac gacaaaagac gaggaaatcg
    23941 ttcaggaatc actggaacac cttgggttag aagaaatagc ggatcaatcg attgacactc
    24001 tttcaggcgg tcaactccaa cgtgcgtata ttgcaatggt gctagcgcaa gacacggatt
    24061 atattttact ggatgaacct ttgaacaatc tagatatgaa ttttgcggtt caaatcatgc
    24121 agattttaaa aaatttagta caagaaatcg ggaaaacaat tgttattgtt cttcatgata
    24181 tcaactttgc tgcaagttat gcagacgaaa ttgttgcaat gaaagatgga cagttattta
    24241 cgcaaggaac gacccaagaa atgataaaaa aagatgtatt ggatgaatta tacgaaatgg
    24301 acatacggat ttgtgagatt gaaggccgca gattctgtct ttatttctaa aactaacatt
    24361 aggagagaag agatgaaaaa attagtagta ggtatcttga ttctagcatc atttggttta
    24421 gcagcatgtg gaaatagcaa caacaccagt caggcagaca caaaaaaaag cagcacacaa
    24481 actgaaacta cattgacgat aacagatagt aatggagacc aaatcgaggt gccaaataat
    24541 ccagaaaaag tcgtcgtatt cgacaatggt tctttagata cgatggatgc tcttggtgtt
    24601 ggagataagg tagttggagc agctacaagc agccttcctg agtatctttc atcctataaa
    24661 aaagtagaat cagcaggtgg aataaaagaa ccagacttag aaaaaattaa tcagcttcag
    24721 ccagatctaa tcatcatttc tggccgacaa agagattttc aaaaagatct aagtcaaatt
    24781 gctccgacca ttttcctttc tttagatgcg aaaaatccat gggaatcttt ccagcaaaat
    24841 gtcactgctt taggggagat ctttggtaag caagaagaag ctaaaactca attagaggaa
    24901 ttatctagtg caatcgatca gacgaaaaag aaagcagaag ctactgacaa aaaagcacta
    24961 gtcacacttg tgaatgaagg gcaattatca gcctacggat ctggttctag attcggtttc
    25021 atccatgatt tatttggctt tgaacaagca gatgatcaaa tcgaagcatc cactcacggt
    25081 caaagtgttt cttatgaata tgtgctggaa aaaaatccgg atatcttatt tgtagtagac
    25141 agaacaaaag ctattggtgg agacgacagc aaagatgata tttctgccaa tgaactggta
    25201 gcacaaacga atgctggtaa aaatcagcag atcatctccc ttgaaccaga tgtctggtat
    25261 ttaagcgggg gcggtttaga atcaatgaaa ctgatgatcg aagatgtgaa tcaagcattt
    25321 aaatagcata aataacagag gattaaactc tcatactatg taacaataat gtttcttaca
    25381 ttcttaaata gcaagagcct atcctcaaag aagttatcaa aaaccatccg taaaatcgta
    25441 ttgatgattt tacggatggt ttttatttat ttgagaaatc ttttttcaac gtgaattcat
    25501 tatctacatc atacgggttg attctagaat ggggagtggc aaaaaatagt gtgatccatt
    25561 ttttcagcat caagatcgcc tcctttgatt tgaatcaaag gtacaaagcg aaacttagat
    25621 aaaacttaaa tttagatatt tttattttgt accgatctct tctttaaacg atgttccatc
    25681 tgctgcttct cggcaataag tccactagac tagaaaatat gagaagctat tttctgtcca
    25741 gcgttcttat tactcaaaac aaatcgcagt tgtcacaatc tcttctaaac gatgttccat
    25801 ctgctgcttc tcggcaataa gcccactaga ctagaaaata tgagaagcta ttttctgtcc
    25861 agcgttctta ttactcaaag caaatcgcag ttgtcacaat ctcttctaaa caatgttcaa
    25921 tcagctgacc ttcggtatta gctcaaagca ctgatttcac aacctctatt taggcatgtg
    25981 tctcagcaag cggttgatag ttgatgatct gcatttttcg ataaaaatcg gcgggaagct
    26041 tactccaccg ttttagtaat tgatagaaat aactctcttc tgctttgatt ttatactcgc
    26101 ttaatatcaa tccaaaacta ttcgtttttt ttgaagctaa ttttttataa atatccaatg
    26161 ctttggtttt atcttcattg acaaagagtg tttttacttc aatataagaa ccctcgatat
    26221 tttgtgtttc ttcgataaaa tagatgtttt ttatatattc cttcatagtg attcctccaa
    26281 agaagtcttt tatttgataa gtttactcta ccgaagagtt gttaataatc cgtgaacaaa
    26341 aagtaattct ttttccaata gttgttaaag gttttttatt ttttatagta ttttttgtta
    26401 tttaagaaag gaataaggtt aaacaaataa caggttgctt tttgggtctt tttccgttca
    26461 agaaactgaa cgaagaaaag ggaaagttgt ctcttttgtg ataagagaaa tcataataaa
    26521 cgaatgactt actttccaat aaattgagaa cagtcagaac cagacaaatt agttgcatct
    26581 gatgaataaa gtgattattc tatgacatga ggtgatacag atgaaattag aagtgacaaa
    26641 agaagcacaa gaagtattga agaataaatt agaagcagac gatcaacttt tattagatat
    26701 cgaaaacggt gacggtccat ttgcagaaag ccaagtcagt tgccaattgg atacggcatt
    26761 tcgattgatc attgtcaaaa aagatacaca aacagatcta agtctttatt ctgtagtggc
    26821 tgatacacca gttggaccaa tcaaaatcaa agacagtgca atactttaca tggatgatcc
    26881 atccacactt gctttagaac caacttataa tagtttacaa ttaaaaggac caagcggctt
    26941 gagaaaaggc aacttgcaag ttgttcgaaa agactagagg gataaaatgg gaaaattggc
    27001 gatcatcagc gacctacatg tggacatcaa taaattcggc gaatcagagc tgatgcagct
    27061 ttggcaagtt ttgcaaaagc acaagatcac tcggcttcat ctagccggag atacggctaa
    27121 taaagtagac cgttgcctag ctgttgtcga atttttcgtc aataaaggat tatctacgac
    27181 atttcatttc ggcaatcacg agttggcaga tgtgcccaat gaacagatga tggaccattt
    27241 tccagaccca cattttttaa atgaacggta tattgcttta aatgagcaga ccgttctttt
    27301 agggatgaat ggctggtacg actatcagtt ttccgaattg aaagattacg aggcaatcgt
    27361 acgaatgaag cgtttgtatt ggtatgatcg gttcatccag cgtgggaaaa cagatctcga
    27421 ggtcaatgca gaaatgcttg cagctgcaaa aaatttgcta gaccagctgg aagcaaaaaa
    27481 acttgaggtg attttatcca ctcatttcgt tcctaaacgg gcatttatca tgtatcaatc
    27541 tgctccttat gagcgttgga acaaattaaa tgcattttta ggatcagaat cattcggaga
    27601 attacttgac cgttattcaa atatcaaaca agtagttttt ggccatacgc atcgtcgctt
    27661 tgaagataaa tccatcggtc acacgattta cagctgcaga ccttttggtt attattatga
    27721 atggcagctg acccgagatt ttgtcttgaa agaacagttg ctagacagct atgatcctat
    27781 gaaattacgt gtcctcttgc gtgcccatca cccagctttt caggcctatc aaacacaaca
    27841 tttgcaagag gaatttgaac aagcgatgac aatcgttccg tattgagaca gcattagtaa
    27901 tgtgtaaaag aaaatacctt gtaaaacata aggataagta agagcagtag atccatttat
    27961 cgtggatatg ctgctttttt tgcggaaaat aatcagcgaa tgtttatttg atcggatgat
    28021 ttgtaactcg cagagtacta gatgcaagcg tgtattcttt ttttgaacga taatcacaaa
    28081 aaaaaatata atatacattt tttatttaat tataattaat attgattgaa gtctaggcag
    28141 tcaagtcaca ttttgataga taggaggggg acttacgaat tattttaaag gctatgacag
    28201 ctgtatttct agattgtgtt tgcatcaagt tgcaataaaa actagaaatc aaatcgggct
    28261 gataatcatt tataactaat cgatacatag gaccaaatat aggtctatgt tcttttattt
    28321 cataagtatc gtaaaacaga attttgctat ggattaatcc aatcgactga tatgtttagt
    28381 aaataaagaa agaggaatgt caatgatgaa aaaagaaatc gtattaacag cagcaatgat
    28441 gttattcagc atggtagcaa gtacgacttt tgtttctgca actgaagtat acccaaagga
    28501 atataacaca gaaggaacga ttacatttga agcaggagat gagggtgtaa ctcctcctgt
    28561 tgatccagag aatcctgatc ccaataaacc tgtcgatcca tcagatcctc caagccctgg
    28621 aacaggaggg gcattatcga ttgattatgg atcaaaattc aaatttggga ctcaaaaaat
    28681 ttctactgcg gataaaacgt attatgcagc tgctgatgtg atgaacgatg ggtctagaaa
    28741 accgacatat gtccaagtga cagataggag aagtacctta tctgggtgga aattaagtgt
    28801 ctctcaacca gaacagttta aaactgccag tggggatgaa ctagttggag cacagctgaa
    28861 atttacgaaa gggcaggctg tttctttggt tgatccaaca tatacgccgc aaacggtgaa
    28921 ttctgaatta acgttgacac cgggaggaaa caatacgtta gcaattaatg ctaaatcagg
    28981 aacaggtgtg gggacttggg tctatcgatt tggtgcaaat gaaaatgaaa atcaagatgc
    29041 ggtacagctt tcggtacccg gtaaatctgt caagttagcg caacaatatt ccactaaatt
    29101 agtttggaca ttagaagata cacctaacaa ctagtttact gaaaagaact gttaaaaata
    29161 aatacgtagt catattgtct tgcgaggtaa tcgagcaaaa attgtcaaag gctaggctaa
    29221 atttgtttgg atacgaatag ttcatctagg aatttaacga tcaggaggaa aagatatatt
    29281 gaaaaagagg aggatcgtgc tcattttaag cagtctctta gtgactaata tctttccgat
    29341 catagggtac tctttggaat tgaatcagtt ggagcatgga aatagaagag acgaagaaag
    29401 caaactcact tcgacattcg acagtttaat agaatccaac cagacacaag aaagcagtga
    29461 ggatttaagt atttcgagta gtggagagac cactgacaac gtagaagctg agggttcgga
    29521 caaacaagga ctagaagatg caccaatttc tgcggttgag ctgcctgacg atcccaatat
    29581 tatttctatc gataaaattt ttcaaacacc tatcggtact agcacgtcca tattggaaaa
    29641 tgggaagtta ctgcagttga acccagcaga aaggtctcaa agaggagcta tttggtcaaa
    29701 taagaagatt agtttactct cggattttac atttaaatct tatttatact taggaaatca
    29761 acgagataga gcgggagatg gcatgacctt tacattgact ggcgatccta gaatggctag
    29821 taatcccagt caagttattg gatcgccagg tatgggaatt ggctcatatt ctactcgttc
    29881 tggccaacct tacattgcga atgcgctctc gattgagttt gatacgtata aaaatagtgg
    29941 ttcttctgat cgaatggatc gagagataac tgctgataat agagggcatg gacatgtcgc
    30001 ttttgtcacg cctaaaccaa ataataataa ttattctgga gagcatactg gcgtgacggt
    30061 agctcctaca tttctttcta atggcacatg gcgcttgtta ataattaaat gggacgcgga
    30121 gcaaagaagt cttacttatg atttggaagg tgtcggtcgc tcttctcgga ttatacctga
    30181 tctcattagg cagtttggtt ctacagaagt aaattggggg tttacttctt caacaggtac
    30241 tttttttcaa gaaaatgctg tcgctgtcac gcgacttcca tcgaatgtca catcaacagc
    30301 tgatgtaaaa gtcaacgata gtgattatgg ggccatcgct gaagctggag gaaacgataa
    30361 gataactatc agaaatacat tgaaggtcga gggggatttt cttgaatata agaaaatgca
    30421 gactagtatc gacctcccac aagaattaac tattcccgag catatcttga tcaatggaaa
    30481 tcaaattgat gccaaagata tcttgataac cggaaatcga gtcacgctaa atctgacaga
    30541 ttattttatt gctggagata cgttaataat cgaattggag acaactttgc aggaagtaat
    30601 tcctgaaaaa gtactcacta tgcattttga ataccttgaa aacgggaatt tgattgagca
    30661 atcgaatgaa ataaacctaa agatcgcaaa gctgaaggag atagatatcc atgtttatta
    30721 taaagataaa gacagtcaga ttgatattgc tgaaatgaaa acaatcactg ggaaaatagg
    30781 agagaagtat aaagaaactc ctattgatat tgaagggtat gtttttgact cggattcagc
    30841 gaatacagaa ggcatcttct ccgaaaatac agaggatatc tatttttatt acagaaaagg
    30901 caaactttat ctctcaactg ctcctcaata tgtcaatttt ggaaaacata aaatatccag
    30961 tagaccatta agtgaattcg gacagttttc aggtgggttg aaaattatag atgaacgggc
    31021 ttttggaagt tggaaattac aattgaaaca agagaaagtt cttacaaatg gagattttga
    31081 gcttccagaa gctctttcct ttgttacctc tgaaaataca acggttatag ggacatccgc
    31141 tgttacgatt ttcgaaagtg atcaaaaggg tgaaagcgat ttgtcctctc ttttagattc
    31201 tacagctcat cgtggaatca gaataaatat tcctgtagaa aaccaaagaa tcggaacctt
    31261 tgaggggaaa ctatcttgga tacttgcaga tgtcccagga aattaacagg aagagaagaa
    31321 tataacaaaa ttattgagtt tcaagaaggg cacaggtacc ataggctctt gtgtcccaca
    31381 gagacaagat tttgttatag tcttctctta catatgatta aaggagcgat tttcttgaga
    31441 ccaaaacaac aattatttat aacactccta gttattttag gggcactttt taacaatata
    31501 tcagtgtcag ctagtgcatt taatttttca gtgacgccga taacttcaga gaatcaaatc
    31561 gacaagagaa aaacttactt cgatcttcaa cttgatccgg atcaggaagt agaagtaaaa
    31621 gcggaattga gaaatgatac agaaaaagaa gtgaaaatcg atatttctgt gaatagcgca
    31681 accaccaatt caaatgtgat ggttgaatac ggaaaaaacg agattgaaaa agacatgagc
    31741 ctgatctttg atctggtaga ttatgtgagc tatccacaga tagtgacgct aaaacctaaa
    31801 agtgtccaaa ccgttgcttt tcatgtcagg atgccgaatg agcgatttga tggtgtattg
    31861 gctggtggga tcacattcca agaaatccag acggaaaagg accaaacaga aactaaggat
    31921 caaagcttat cgattgagaa tgaatacacc tatattattg ctttgttgat gcaacagaca
    31981 ctgaacgaag ttgctccgaa ccttactctt catgaagtta aaccagatca aatcaatgca
    32041 agaaatgtca tcttagcaaa cgttcaaaat gatcaaaaaa cctatatcaa tcaagtagtt
    32101 attgaaacaa aaattacaaa aaaaggacat tctgaagttt tatatcaaga ggaaaaagaa
    32161 ggattgcaga ttgcgccgaa tacaaatttt tcttttccaa ctgctttaaa tggtcaaccg
    32221 ctaaccccag gtgaatatca ccttacaatg actgttttag gaaatgaaaa tgaaaatgga
    32281 aaattttcga gaaaaaaagg aaatactacg atcaactata ccaatcaatg ggtatttgaa
    32341 aaagatttta caatagacgg aaaagtagcc aaggaattga acacgacgga tgttacgatt
    32401 aaaaaagaca ataattggat ttatatctta gtagcttcac ttttcttatt gtttatttta
    32461 ttatgcatac ttttgtttgt tttgagaaaa aaagaagaga aagaaaagta aggttaagat
    32521 aacaaatagt aaatttttat tattgtagga tggttgggct ctttttataa caatataaaa
    32581 tataccattt tattaataaa aatgcatact agtaaatgat ataattctaa taacaggttt
    32641 gatcgcgaga aaggccaaat aaaacgctct ccaaaatgtt aaaaaaaaga caggacgatg
    32701 tatattatac aaacaagaat cgctgacaac agtgactcgg atccaggaaa tcagttttat
    32761 ccccagctag ttggtgaatg catggaaagt aatatacgta gaaagagctg atgactaatg
    32821 aattatgagt tttttttaag caaagaagat cacagaagtt attcattact taaatattta
    32881 gaagcaagct caaatttatc agagtcaata tcgaatgttc aagaagagtt gtcgctatcg
    32941 acatttctct tgaaaaaaac gatcgataag ctgaaacatg atttacaaaa gttcgatcta
    33001 gagaaaaatt tgcgagtaac cgtcagtgaa ttggatatat gtctggaaat taatggaaaa
    33061 tgttctagca aagctctgtt atctcgttat ataacggatt ctttatctat gaaaatggta
    33121 ttggctttct ttcaggaaaa atatatctca gtagaaaatt ttgctaaaca gcatcacgtg
    33181 agttattctg tggcttataa agtattacaa agactaaaaa gaaatctaaa aaaatatcaa
    33241 attttttttg aaaagagaaa gtt
//
LOCUS       DAFENC010000030        32533 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.030, whole genome shotgun sequence.
ACCESSION   DAFENC010000030
VERSION     DAFENC010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32533
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.030"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            131..505
                     /locus_tag="LP493_001788"
     CDS             131..505
                     /locus_tag="LP493_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBL2133940.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="LP493_001789"
     CDS             complement(619..1248)
                     /locus_tag="LP493_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBL2133941.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="LP493_001790"
     tRNA            complement(1382..1454)
                     /locus_tag="LP493_001790"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="LP493_001791"
     tRNA            1668..1741
                     /locus_tag="LP493_001791"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
     gene            complement(1879..2043)
                     /locus_tag="LP493_001792"
     CDS             complement(1879..2043)
                     /locus_tag="LP493_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133942.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2338..3666
                     /locus_tag="LP493_001793"
     CDS             2338..3666
                     /locus_tag="LP493_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HBL2133943.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3868..4701
                     /locus_tag="LP493_001794"
     CDS             3868..4701
                     /locus_tag="LP493_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HBL2133944.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4717..5454
                     /locus_tag="LP493_001795"
     CDS             4717..5454
                     /locus_tag="LP493_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HBL2133945.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5609..6577)
                     /locus_tag="LP493_001796"
     CDS             complement(5609..6577)
                     /locus_tag="LP493_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HBL2133946.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6809..7642
                     /locus_tag="LP493_001797"
     CDS             6809..7642
                     /locus_tag="LP493_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HBL2133947.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7676..8515
                     /locus_tag="LP493_001798"
     CDS             7676..8515
                     /locus_tag="LP493_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL2133948.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8541..9101
                     /locus_tag="LP493_001799"
     CDS             8541..9101
                     /locus_tag="LP493_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBL2133949.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9300..11021
                     /locus_tag="LP493_001800"
     CDS             9300..11021
                     /locus_tag="LP493_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HBL2133950.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11186..12328
                     /locus_tag="LP493_001801"
     CDS             11186..12328
                     /locus_tag="LP493_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBL2133951.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12344..13555
                     /gene="thiI"
                     /locus_tag="LP493_001802"
     CDS             12344..13555
                     /gene="thiI"
                     /locus_tag="LP493_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HBL2133952.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14128..14775
                     /locus_tag="LP493_001803"
     CDS             14128..14775
                     /locus_tag="LP493_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBL2133953.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    14904..15120
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15168..17813
                     /locus_tag="LP493_001804"
     CDS             15168..17813
                     /locus_tag="LP493_001804"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBL2133954.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18123..19436
                     /locus_tag="LP493_001805"
     CDS             18123..19436
                     /locus_tag="LP493_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HBL2133955.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19426..20079
                     /locus_tag="LP493_001806"
     CDS             19426..20079
                     /locus_tag="LP493_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBL2133956.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20134..20826
                     /gene="radC"
                     /locus_tag="LP493_001807"
     CDS             20134..20826
                     /gene="radC"
                     /locus_tag="LP493_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBL2133957.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            20976..21176
                     /locus_tag="LP493_001808"
     CDS             20976..21176
                     /locus_tag="LP493_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL2133958.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(21430..23109)
                     /locus_tag="LP493_001809"
     CDS             complement(21430..23109)
                     /locus_tag="LP493_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBL2133959.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(23111..23323)
                     /locus_tag="LP493_001810"
     CDS             complement(23111..23323)
                     /locus_tag="LP493_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HBL2133960.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            23716..25446
                     /gene="efrA"
                     /locus_tag="LP493_001811"
     CDS             23716..25446
                     /gene="efrA"
                     /locus_tag="LP493_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HBL2133961.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            25443..27203
                     /gene="efrB"
                     /locus_tag="LP493_001812"
     CDS             25443..27203
                     /gene="efrB"
                     /locus_tag="LP493_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HBL2133962.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            27298..27495
                     /locus_tag="LP493_001813"
     CDS             27298..27495
                     /locus_tag="LP493_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133963.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            27648..28133
                     /locus_tag="LP493_001814"
     CDS             27648..28133
                     /locus_tag="LP493_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HBL2133964.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(28237..28830)
                     /gene="clpP"
                     /locus_tag="LP493_001815"
     CDS             complement(28237..28830)
                     /gene="clpP"
                     /locus_tag="LP493_001815"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBL2133965.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            29010..29537
                     /locus_tag="LP493_001816"
     CDS             29010..29537
                     /locus_tag="LP493_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133966.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            29628..30365
                     /locus_tag="LP493_001817"
     CDS             29628..30365
                     /locus_tag="LP493_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBL2133967.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            30369..31286
                     /gene="miaA"
                     /locus_tag="LP493_001818"
     CDS             30369..31286
                     /gene="miaA"
                     /locus_tag="LP493_001818"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HBL2133968.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            31288..32517
                     /gene="hflX"
                     /locus_tag="LP493_001819"
     CDS             31288..32517
                     /gene="hflX"
                     /locus_tag="LP493_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBL2133969.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT        10772 a         5522 c         6874 g         9365 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaaataaag cttatgcaaa gaaaaagaaa tccaatcact tgggtttctt tttcttttat
     1801 tattatgatg aatcaagctt tctgtttttg tcacgtatgt tgtaatcttt acgaaagagt
     1861 agagttggct actcataatc aaccatactt cccatcatcg ctaaatacga aataaatcag
     1921 cattcctaca ccaatcaaag cacaagctgc accaagaaaa gggatgacat tcccaaagtt
     1981 atctgtattc ataagtatgc caccacccac aaacaaaaag ccgccagcaa tcaggttttt
     2041 cattttattc atctcctttc ttacgttata gtatttcctt ctttcaatga gtattttgaa
     2101 agctatctta ttgtatgatg ttcttctagg cctcttcttt attatacagg ccattttcgt
     2161 tatctcatag aaatattcct ttttatctga aaactattgt ataccgtatg acatttttct
     2221 tcatgaagtt gtaagtatat tctcattcaa atgaaaattt catcatagaa gagattgtat
     2281 ttctaaattc ttaagagtaa aatacgaagt ataacttgga tttggaagga tgattggatg
     2341 aaagctatta cgcctgatat gacaacaaaa tttaacaaac agtttcaagc aaatatcaaa
     2401 cagcaggcat tgcagcgggc agttgtgaag aacggaatta ctgcttctgc tgaaaatgtt
     2461 tcagcacatg tggagaatac accggtattt tctatagatt tggctacggg gaaagtggct
     2521 aatcaaatgc aatcggggcg ttgctggatg tttgctgcac tgaacacatt ccgtcataag
     2581 atgctgaatc aattccattt aaaagagttt gaattatcac aaaattacac ttttttctgg
     2641 gataaatatg aaaaggcaaa ttatttctat gaaaacatca ttgcaacagg aaaagaggca
     2701 atcgatagcc ggaaagtagc tttcttactc gctactcctc aacaagatgg cggccaatgg
     2761 gatatgatcg tttcattatt ccaaaaatat ggcgttgtgc ctaaatcggt gatgccggaa
     2821 agtgcgaata gttcaaattc tcgagatttg aataactact tgaacaaatt actgcgtaaa
     2881 gatgcagtag tgttacggaa aatggttgct caaggagaaa cattagacgc tattgaagaa
     2941 aagaaagaag aaatgctaga aagcatttat aacttcttag ctatctcatt aggaacacct
     3001 ccaaaagaat tcgattttga gtaccgcgat gaagaaaaga actatcatct tgaccgagga
     3061 ctgacaccac aaatttttta tgataaatac atcggtgtaa aattagatga ttatgttagc
     3121 gtgatcaatg caccaacaaa agacaaacca ttcaatcgtt cttatacagt agagatgcta
     3181 ggaaatgtcg ttggcgggaa agaagtcaaa tatctgaatg ttgatatgga aactttcaaa
     3241 aaattagcga ttgctcagct tgaagaagga gaatctgttt ggtttggttg tgatgtaggt
     3301 caatcttcta ctagaactag tggcatcatg gccttagatg cttattcaat ggatgatcta
     3361 tttgatacgg attttacaat gactaaagct gaacgtttag attttggaga aagtctgatg
     3421 acccatgcga tggtattgac cggtgttgac ttagtagacg ggcaatcaac aaaatggaaa
     3481 gtcgaaaata gctggggcga aaaagttgga aagaatggct tctttgttat gagtgatgcc
     3541 tggatggacg aatatacgta ccaaatcgtt gtaagaaaag atttattgac gaaagagcaa
     3601 ttaaatgcgt tcaatgaaga accaattgtt ctatctccgt gggatccaat gggtgcttta
     3661 gcatagacga gtatttcaat gaagagtatg tagtaaagat aaaaagagct ggcttaagcc
     3721 agctcttttt atctttaaag tccattccct gttttttatg gtccctgtgc tataattcta
     3781 aataaaggat aaggattgga aataatcctt ttatcattaa aaatatgatg acgaagtaga
     3841 ataaaattgg gagtaggggg gaaagtcatg gatatccaaa ctgttttatc tgatctgaaa
     3901 ttaaatggta aagtgattcc agttgttggt ggcgatgtta atcagaccta tcgtataaaa
     3961 accgaacatc gtgcttattt tttaaaaatc catccgaatg taaaaaaagg attttttgaa
     4021 gcagaagtag acggattaaa agaactgtca gcattcgtac gtgtaccgga tacgtatatg
     4081 ctaggtgaaa caagtgaagg cgcttatttg ttaatggaat ggatcgagcc gggaaaaggg
     4141 gatcaacgag atcttgctgc agctttagct aatctccatc agcaaacagc gccacaattt
     4201 ggttttcgta aagataacta tttgggtaca cttgttcaga aaaattcttt tgaagaagat
     4261 tggtggactt ttttctttaa agatcggctt gaatcccaga tttctttggc agaagaaacg
     4321 aatcgatgga atgtacagcg tcaagaaaag tatctgcgat ttaaagaacg tgtattgaaa
     4381 tcggttgaac caaaaaagat cactccacgc ctcttgcacg gagacctgtg gagtggtaat
     4441 gtgttctttg accagcaagg gcatccagtt tttgtcgacc cagctgtttc ttatgggaat
     4501 cgggaacaag atattgcaat gagccagtta ttcggtggtt tccgaccgga atttttagat
     4561 gcttatcaaa ctatatttcc attagaaaag ggatggaaag accgactgcc gatttaccag
     4621 ttatattatc ttttggcaca tttgaatatg tttggagaaa gttacggttc ccaagtagat
     4681 caattactag aaaattttta agaggagggc gtgtttttgg caaaaaaata taccaaaaag
     4741 catgaagttt catattatga gtgtgacatc aaccaaacga tgacatttcc ttcgatgtta
     4801 ggagtagtta tcaaaacgtc tgaagatcaa agcgaccagt tgggaagagg cagtgaattc
     4861 gtcaatagct ttggacttac ttgggtcatc acgaattatt ccatggagat taatcgtctc
     4921 cctagagtcg gtgaagtaat ctcagtaacg actcaagcca tggagtacaa taagtttttc
     4981 tgttatcgga acttctggat ccatgatgaa gatgggaaag aattagtcaa aatagaatct
     5041 gttttcgtat tgatggattt tgtgaatcga aaaatgagca gtgttaatga agagatcatt
     5101 gctccttttg agagtgagaa gatcaagaaa atcaagcgtc aggaaaaaat tgaaaagatt
     5161 gattcgggct tcatgttgcc atatcgtgtt cgtttttatg atatcgatag taatcagcat
     5221 gttaataatg cgatgtattt taattggatc attgacgtat taggatatga ctttttgact
     5281 acgcatgttc cagaaaaagt aattattcga tttgataaag aagtagagta cgggaatgag
     5341 atcgaaagcc attttgaaca aatccctatc gaaaatggtg tcaaaacaaa acatgaaatc
     5401 cgaatgcaag aacagctgta ttgtgaagca aatattatat ggaaaaataa ataaaaaaga
     5461 ggttgtgaca gaagggggca acttcaagaa ataagaagaa atttacgaaa attgtttctc
     5521 aaatttttgt aaattttcga cttagttttc gaagaagcta tttttgtcac agcctctctt
     5581 tttaagttta gctattagat aatgatgttt agttttggat aaacgaaatc aattcttcac
     5641 ccgacaaacc atagtttaca gcaatcaata gttttaaacg tgctttttga ctattaatac
     5701 tgttacagaa aataatcccc attttttcta gttcttttcc cccgccttca taatcataaa
     5761 caggctctgc gattccattg aaacaacgag aaacaagtac tacagggatt ttttggacaa
     5821 gaagcttttc caaagcagct aaggcttgtg gagggagatt ccccgcacct aaagcttcga
     5881 ttaccaaacc gtctactttc gtatgggcga tggcttccaa taagtcccct tgcatcccag
     5941 catatgcttt aacgatcggg atagtcccat ctacagcgga aatgtccagt cgctttgttt
     6001 ctaaaagttc ctgcaagaat aaaattcgat tcttagttac taagccgatg ggacccaatg
     6061 taggtgttcg gaaagtagca acatttgtgg tatgggtctt tgtcacgtag cgtgcagaat
     6121 ggatctcatc gttcatgacc accaaaaccc ccttatctag cgcttcttca caacttgcga
     6181 cacgaatcgc actttcaaaa ttataaaggc cgtcacttcc aagttcatta cttgaacgca
     6241 ttgccccagt caaaacaatt ggtaatttgt tgccaatcgt tgtatcaaga aaaaaagcag
     6301 tttcttctaa tgtatctgta ccgtgtgtga tcaccactcc ggatatacct gatgcataag
     6361 cggacaagat acgttctttt aataccaaca tgtgagaagg catgatgtgt ggtgagggaa
     6421 gattgaagat atcttcaact aataattcta catgcttggg gattgtgatt tctgcatcta
     6481 ataatgggtt tgccacatca ggactaacac cgcccgtgag catgttttct ttcatggcga
     6541 tcgttccgcc ggtgtgtagt acaagtattt ttttcatttt acagacttcc ttacgaataa
     6601 ttttgcatag ccgttaaatc ttattgtata ctatataaaa gagttttgct atcagtgaag
     6661 aataacgaat agcctaactt atcataaaaa agctgacctt attaaaatgg aaaagactca
     6721 accttgacct cctaatacaa tggagtatct ggttgagttt cttttacaag aaagcagcca
     6781 aggaaatcaa tcacgaaggt ggccggaaat gatcagaatc ggattaacat cgtttaaaga
     6841 acatgacaaa ttaactggta aaaagaataa cactctttat gaatatgcag ggtttctacc
     6901 cttagtggaa ttagatactg cctattatgg aattccccga aagtcctcag ttgagaattg
     6961 gataagtgaa gtacctgaat catttcgctt tgtagtcaaa gtctatcaag gaatcagcgg
     7021 tcaaggagac tggaagcctt attatcagac cgaagaagag atgattgcgc attttttaga
     7081 tgttatgtcg ccaatggtag atgctggaaa gatgttttgc tttttagtcc aattcccctc
     7141 atcattcaaa tgtacgaaag aaaatgtcca gtacttgcgc aaacttagaa agtggtttga
     7201 gggttatcct gtttctatag aattgcggga ttattcttgg tacagcgatg aatttcttga
     7261 acgtacaaga aactttatgt ctagagccgc tttttcttta gccatcatcg atgagccaca
     7321 gttgctgaat acaacgattc cttttgatcc atttgtcacc aatccgaact ttgctctttt
     7381 tcgattccat ggtaggaatg cgcaaggatg gcaagcaaat gataaagagt ggcgtaaaaa
     7441 aagaacgtta tatcgttatt cagaaaaaga actgcaagaa ctagcacatg aagtcaaagt
     7501 agttgattct aagacaaaag aggtaggtgt gatttttaat aataattctg gtggtgatgc
     7561 ggctgaaaat gcattagcac tgcaaaaaat attaaatatc aagccagatg gactcaatcc
     7621 aacccaaatg gatctgtttt aagggcttat tttattcaag aaaggggcga agtctatgat
     7681 caaagctatt ttttttgata ttgacggaac attggtcacc aatcgttcaa aagcgttgga
     7741 atcaacaaaa caagcaattg aatatgctcg gaaaaacggc attttatgcg gtgtagcaac
     7801 ggggcgcagc ccagtaaaga tcaaagaaat cattgatgaa ttggaattag atatgtatgt
     7861 cgtgtataat ggtcaactgg tttttactgc agatcgcacg attatcgacc acccttttga
     7921 acaaaaagta ttggaacata ttgttgaatt tgcagatgag aaccatcgac aaatcgtttt
     7981 tggtgcgaga aatcggttag atggatcaac gacgatgcta ttaggacaat cgatttttat
     8041 caagcgacta gtcagctttt taccgcgtaa attcccggta cgtctgatga aaaaaatcct
     8101 ccaggttttt agccctcacc gacaaaagga tcgttatgaa acgttagaga tattaaaaga
     8161 accaatttat caatgtatat tgctcagtcc ggagtcagaa cagaaaaagt tagaacatcg
     8221 ctttcccgag tgtacgtttc agcgttcaaa tacgtatact gtagatatca tcccaaaagg
     8281 tggttcaaaa ttactaggca tccaagcttt cgcaaatgct gtcgaaattg aaatggaaga
     8341 aattatggca ttcggcgatc attacaatga tatcgagatg ctgaaaggtg taggaattgg
     8401 agtggccatg gggaatgctc agatcgaagt aaaacatgct gcagactttg tgactcaatc
     8461 aaatgaagaa gatgggatat acgaaggact gaaacacttc ggtctgattt attagtcaat
     8521 gaaagaagga aaaaatcagt atggaagcag agacaccttt tcaaaaagta gaaacattcc
     8581 acaaaacttt tgatccaaga agaccagaga tacccacggc ttttacagaa aatgaagctc
     8641 atacacgtgc tgcgttcaaa atagaagaac ttgttgaatt tgttgcagct acttcaccta
     8701 ataaagaaca actgcatgaa gctgttatgc tgctgcacga agcattagat aaagcagaag
     8761 aaaaaatact tggtaaaaca cagtggggaa gtgatccgct ggttgaacaa gtagatgcac
     8821 tgacagatat cctttacttt acttatggtt ctttttcatt actaggaata gtgcctgatc
     8881 gaatattcga aatcgtccat caggcaaata tggggaaatt atttccagat ggaaaacctc
     8941 attatgaccc tgtaacaaat aaagtgttga aacctgaaaa ctggcagatg gaatatgctc
     9001 cagaacctaa aatcgcggca gaaatccaac gtcagattca agaagcgatt gctaagaaga
     9061 aatccgctga tataggcatg tgcacaaatg aaaaagagtg atcagagttt cactattttt
     9121 gttatcttta tacgatggaa aaacaaaaga ttttcgttta agttagtgaa tgcatgaaaa
     9181 tagtatgcta taatctagaa tagatgtctt ttgcacgaga gacgtattat ttggatttat
     9241 gccaagcaga acgccatctg ttgcataaaa gatgcatact gaaaacggag gaaccataaa
     9301 tgggaaataa tgttatcatc ggaatcgtca ttgcaatcat tatagtcgcc attgtcgtct
     9361 ttttggttag ttacttgatg aagaaaaaaa accaagatcg attggatgcc ttagaaaaac
     9421 gcaaggaaga attatttgac ttgccagtga ttgaagaagt cgatgatgtt aaaaaaatgc
     9481 atctggttgg gcaaagccaa aatacctttc gtgaatggag tcaaaaatgg aatgacatat
     9541 ctacttcctc gttcgctgaa ctagaaagtc aaattttcga agtggaaaac ctcaatgaaa
     9601 gttttcggtt cttaaaagga aaaaaagcag ttgttgaagc agaagctaca atggaccaaa
     9661 tggagaaaca agtgacggaa atccgtgaag gtctaaagga attgcgggaa acggaagaac
     9721 gcaactcact agctgttcag caggcacttg acgtctatga agaactgaaa gaaaaagtca
     9781 gagaagacga gcatgaatac ggaccagctc tttttgaatt gcaaaaacag atcaaagtga
     9841 tcgaaaaaga atttacgcag tttgtgactt taaacacttc tggagaccct gttgaagccc
     9901 gcgaggtttt ggataaagca gaaaaacata cgtatgaagt ggaagctctg atgaaaaaaa
     9961 ttccaccgct gtatgaggag ctccatacca ctttccctga acaacttgaa gaaatcagtg
    10021 atacttacga gaaattgatg gaagaacaat atgtattccc agaagaagat cttgctgaag
    10081 atatcgcaaa agtaagtcga agaattgaaa attcattagc caatcttgaa aaaacagaag
    10141 ttgaaacggt cgaatttgaa aaccgtgaaa cagctgattt gattgattcg ttatatgata
    10201 tcttagaacg ggaaatggaa gctcagagat atgtaaaaac taaccaatca acgattgcag
    10261 agtatatcaa acatacaaca aagaataacc gtcaattatt gattgagctg gatcacacat
    10321 ctcaaagcta tacattgaac cacaatgaaa ttggccgtgt acgaggtttc caaaccgaag
    10381 tggaagaaat ggaacgtcaa aatgaacaga tgattccaca gatccgtcaa cacgaaattc
    10441 cttattcaga agtgcgcacg ttctataaaa cagtcttcaa agtcttagaa gatatcgaaa
    10501 agcaacaagt agagatcgac gactcattac atgaattgag aaaaggcgaa aaagaagcgc
    10561 aagaaaagat cgatacattc gaattcaaat tgcgcagttt gaaacgtttt gtagaaaaac
    10621 aacgtttgcc tggcttgccg aatgattacc tagaattctt ttttgttgct actgaccgta
    10681 ttgaagaact aagtgttgtc ttgaataaaa ttcgagtaaa catggaagag gtcaatcgtt
    10741 tagttgctct atgtgaagaa gatctagaat tattagataa gaagacacat gatttagtag
    10801 atgcagcagc attaacggag caaatgctcc aatatgcaaa tcgttatcgt catacacacg
    10861 aagaagtgag agaagcaatt gataaaagct actatttatt caataaagaa tatcactatc
    10921 aagaagcatt agacgaaatc ggtacagcat tagagcgagt agaacctggt gctttcaaac
    10981 gcatcgaaga tttttatttt aatcatccag acttagtata aagcaaaaaa gttagtaaac
    11041 cagcaagagc aagacggatt attgtcttgt tcttgtcttt ttttgtatat ttgaaaattg
    11101 aaacaagtga aaatttcacc tgctcttgaa agcaccttgg acaaccgtta taatagaaaa
    11161 gaatttcaaa aaagaggggt ttcttatgat atattttgat aacagtgcaa caaccccaat
    11221 ctttccgcaa agcttagatg catatgtaaa aaccagtcag cggattattg ggaatccatc
    11281 aagcttgcat gatttaggca atcaagctaa ccggttgttg cagcaagcaa gaaagcagat
    11341 cgctgatttg atccatgtag aaccagaaga aatctatttt acttcaggcg gaacagaagg
    11401 agataactgg gtattaaaag gaacgatgat cgaaaaaaga gaatatggga atcatatgat
    11461 catttcagga gtcgaacatc cggccgtcag cgagacagca gaacaattaa aagaattagg
    11521 aatcgaagta agtatcgccc cagtggataa acgcggattt gtacgtgtcg acgaattgaa
    11581 agaattaata agaaaagaga cagtattagt ctctgttatg gctgtgaata atgaagtagg
    11641 atcgattcag cccatccagg aaatcagtga tcttttggat gattttccta aaattcattt
    11701 ccatgtagat gctgttcagg cgattggaaa agtaccattc tcgcaatggt tgacagaaag
    11761 agttgatttt gcaacatttt cagctcataa attccatggc ccacggggaa ctggtttcat
    11821 ttattggaaa aagggtcgtc gtttagcacc attactgaca ggtggagggc aagaaagaaa
    11881 tcagcgaagt gggacagaaa atgttccagg tattgtggct atggttaaag ctttacgttt
    11941 atcattagag ataaaggaac aaaaacctga gcagacacaa cgcttaaaag tagctctaat
    12001 caatgcgttg aagacgtatg agaaagtgac gattttttca gaaggaactg actatgcacc
    12061 gcatatttta tgttttgctc taaaaggaat tcgcggcgaa gttctcgtcc atgccttaga
    12121 agaaaaacaa atatttgttt ctactactag tgcctgctcc tcacgtaaac atatggcaag
    12181 cagtacattg cacgcaatgc atgtaccaaa tgatctggct acatctgctg ttcgaatcag
    12241 cttagatgaa aacaattcgc ttgcagaagt cgagcaattt atgattattt tcaagcagct
    12301 ttataagaaa ttttctgcaa tcaattaaaa gaggagtgtt cttgtgaaat acagtgaaat
    12361 tatggtccgt tatggggaac tttcgacaaa aggaaagaat cgaaaaagct ttatcatgca
    12421 actagcacaa aatgtcagac aagctttgaa agactttcca gaaatcaaaa tccatgctga
    12481 tcgggaccgg atgcatcttt tattgaatgg cgcagacggg cagctagtta ttccaaaact
    12541 agcaaaaata tttgggatcc aaaatttctc tccaagtatt cgtgtagaaa aagatgtcga
    12601 agttttgaaa caagctgttc aagacatcat gaaagaaatt tatactggga aagaaacatt
    12661 taaaattatc gctaaaagaa gcgatcacca atttgaattg acaagtaatg aattgaatca
    12721 aacattaggt aatgctgttt ttgatatttt cccgcatatc caagttcaaa tgcgtcaacc
    12781 agatattcca ttacgtgtag agattcggcg tgatggcgct tatctatcgt atgaaacgat
    12841 caagggagct ggaggattgc ccgtaggaac aagcggaaaa ggaatgctta tgctttctgg
    12901 ggggattgat tctcctgtag cagggtactt tgccatgaag cggggagtgg aaattgaagc
    12961 tgttcatttt gctagtccgc cgtatacaag tgaacaagca ctgcaaaaag caaaagatct
    13021 aacagccaaa ctagcacctt atgtgggaac gatccatttt atcgaagtgc catttaccga
    13081 gattcaagaa gaaatcaaaa agtcagtgcc acaaggatat tggatgacaa ttactcgtcg
    13141 aatgatgttg cgtttgaccg atgaaattcg ccgtattcgt catggtttag tcattttgaa
    13201 tggtgaatca ttaggtcaag tggcttcaca aactttgcaa agtatggtgg ctatcaatga
    13261 agtaacgaat acgccaatca ttcggcctgt agcgacaatg gataaacttg aaatcattga
    13321 agtagcagaa cagatcgata catttaatct ttctatccag ccttttgaag attgctgtac
    13381 gatttttgct cctccacagc caaaaacacg ccctcaactg gaaaaggtcc atcaatatga
    13441 agagcgttta gcaatagatg aaatgatcca acgagcacta gctggcttga agatggaaga
    13501 gatacaagca gaatcgtcta atgaaaaaac tgaagaattt tcagaattgc tataagaggt
    13561 tatgaaaata gtgttttgac cagagtatta gagaaacaaa acgaaaaaat agctccatgt
    13621 attttaccgt ttttgaacta atgtcgaaga ttagctgatt gaataccatt tatcaagaag
    13681 ttatggaaaa gccggttctt ttttactaac tgaaaaataa aattttattt agagatcaag
    13741 ctacagttga taaatgatat aaaaaagaga atttcccatg aaatagcgag gttgtgacag
    13801 aagtgggcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttttca aatttttgtg
    13861 aaatttcggc ttatttttcg aagaagttac ttctggaaca ccgtgtatca gaggttgcga
    13921 aaaagctgcc ctgcatcaag taataagaac agccaaacaa aaatagttcc tcatatttta
    13981 cgtttggttg agcttattac cgcagatgca agcttttgaa caccgtttta tttgtctcac
    14041 acccttttcc ttcctacttg taaccttgct cccgtgttag aaacatgtta cactaaatat
    14101 gtgaaattat taacaaggag cgtcgttatg cgagaaaaaa cagatacact gccaaaagca
    14161 actgcgaaaa gattaccttt atatttacgc tacttgaaga tgctggatga ctcaggtata
    14221 agtagaatca aatcaaatga gttcagcgaa atcacccaaa ttccttctgc aacgatccgc
    14281 agagacttct cgcaattagg cgagctaggc agaagcggat atggctatga tgtccctttt
    14341 cttatcgatg tattcaataa tatccttaat actaaagaag aaaaacgaat cgcattagta
    14401 ggatatggaa atcttggcaa agcattgaaa cacaacaatt ttagaagaaa tgaaaatcta
    14461 aatatcgtgt gcgtctttga taatgatcca gcactgatca atcgagtaat tgatggagaa
    14521 atgatctatc cgattgatcg tttcgcggag atagccaaag caaaaaatgt gacagtagca
    14581 atctctacgg taccaagtaa atattcacaa tctgctattg atgaaattgt caaaggaaat
    14641 gtaaccgcta tacttaattt tgcgcctgac agagtaactg tcccagctta tgtcaatgtt
    14701 caatacattg atttgacaac cgagttgcag acgcttattt actttgatga gaattactca
    14761 gaagtttttt cttaggaaaa tttgagtagg cttattgatc ttgcgagaac tcgtcgtaat
    14821 tctttcaaaa attttttagt actaaatgaa gtggtttttt cacgaccact tgttgactaa
    14881 aaaaaaaaac cattgtagaa tgaagcataa cgctgaacaa gaggagtaac tggcacattc
    14941 attcttagag agagaactat ctgctgaaag gttctcaatg acaaccagtg aaggtagctt
    15001 gggagtttct gtcttgaatg gagtagagat agacgagtcg tgatcgttaa ctcacttgag
    15061 aggcaataat gattgattat tgcaatttag gtggtaccgc gtaaatcata cgtcctagaa
    15121 tacgaaagta ttttaggacg ttttttagtt taaaggagga aaacagcatg acggaagaaa
    15181 ataacctatc aacaaaatat aatccgcaag aagttgaagc tggacgttat cagcattggt
    15241 tagaacaaga tttgtttaaa ccgagcggag ataaaaaagc aaaaccttat tcaatcgtaa
    15301 tcccgccccc aaatgttact ggaaaacttc atttagggca tgcttgggat acgaccttgc
    15361 aagatatgct gattcgtcaa aagagaatgc aaggatatga tactttatgg ctgcctggta
    15421 tggaccatgc aggaatcgcg acacaagcaa aagtagaagc gaagcttaga gagcaaggga
    15481 tttctcgtta tgatctaggt cgtgaaaagt tcatcgatca agtgtgggaa tggaaagaag
    15541 agtatgcgag ccacatccgc gaacagtggg ctaaaatggg cttatcttta gattacagta
    15601 gggaacgttt tacattagat gatggattat ctgaagcagt acgtaaagtt tttgttacct
    15661 tatacgaaaa aggtttgatt tatcgtggtg aatatatcat caactgggat cctcaagcac
    15721 gaacagctct atctgatatc gaagttattc ataaagatat cgaaggcgcc ttttatcata
    15781 tgagctatga actagcagat ggatcaggcg tagtagaaat tgcgacaacc cgtccagaaa
    15841 cgatgttggg agatacggcg attgctgttc atccagaaga cgagcgttat caagcgctca
    15901 tcggcaaaaa agtgattcta cctttagtca ataaacaaat cccaatcatt gcagatgaat
    15961 atgtagatat ggaattcggg acaggtgtag taaaaatcac tccagcacat gatccaaacg
    16021 actttgaggt aggtaatcgt catgatcttc cacgcgtaaa tgttatggat gatgatggta
    16081 cgatgaatga actagcagga aaatatgctg gaatggaacg ttttgctgct cgtaaagcaa
    16141 tcgtgcaaga tctgaaagaa atcggtcgat tgattaaaat cgatacgatg atccacagtg
    16201 tgggtcattc cgagcggaca ggtgtcgttg ttgaacctcg gctgtctact caatggtttg
    16261 taaaaatggc gccgttagcg aaaaaagcca ttgataacca agaaacagat caagcagtgg
    16321 aattcttccc tccaagattc aatcaaacgt ttttacgttg gatggaaaat gtccatgatt
    16381 gggtaatctc acgacaatta tggtggggac atcaaattcc tgcatggtat cacaaagaaa
    16441 caggtgaaat gtatgtaggg atggaagcac cagcggatag tgaaaactgg gtacaagatc
    16501 ctgatgtttt agacacttgg tttagttcag ctttgtggcc tttctcaaca atgggctggc
    16561 cagatacgga aagcgaagat tataagcgat acttccctac tagcacttta gtaaccggtt
    16621 atgacatcat tttcttctgg gtaagcagaa tgattttcca aagcttggaa tttactggcg
    16681 aacgtccatt tgagaatgtc ttgattcatg gattgattcg tgacgaacaa gggcggaaga
    16741 tgagtaaatc attaggtaat ggaatcgatc cgatggaagt aatcgaaaag tatggagcag
    16801 atgctctccg ctggttctta tcgaatggtt ctgcaccagg acaagatgtc cgcttcagct
    16861 atgaaaaaat ggatgcttct tggaacttta tcaacaaaat ctggaatgct tcacgtttcg
    16921 ttatcatgaa tatcgaagga atgaccgtag aagagatcga tttatctgga gaaaaatcag
    16981 tggctgaccg gtggatcctt actcgtttga atgaaacgat cgaacgagta actgagctat
    17041 ttgatcgttt tgaatttggt gaagcaggtc gacaactgta taactttatc tgggatgatt
    17101 tttgtgactg gtacatcgaa atgagtaaag aagtacttta tggagatgat gctgtttcaa
    17161 aacaaaccac ccgtagcatc ttagtccata cacttgatca gatcctacgt ttattgcatc
    17221 caatcatgcc attcgttaca gaagaaatat gggaacatat tcctcatcag ggaaattctc
    17281 tagtagtggc agaatatcct gttgtacgtc cagagtttga tgatgaaaca gcttctaaag
    17341 ggatggaagt attgaaagaa ttgattcgag ccgttcgaaa tattcgttca gaagtgaata
    17401 caccattgtc taaaccaatt acgttgctaa ttaaaacaaa cgatgctaaa atcgatcaat
    17461 ttttagttga aaatacaagc tatatcgaac gcttctgtaa tcccgaagag ttgacgatat
    17521 caagtgagat cactgcgcca gatctagcga tgtcagctgt tctgacaggt gcagaaatct
    17581 tcttgccgtt agcaggattg atcaatattg aagaagaaat caaacgatta gaaaaagaac
    17641 tggaaaagtg gacaagcgaa gtaaaacgtg tccaaggaaa actttctaat gaacgttttg
    17701 tttctaacgc gccggaagaa gtagtagagg cagagcgtgc aaaagaaaaa gattatttag
    17761 agaagcaaac ggctgtcaaa gaacgaatcg aaagtttgcg tactattcaa taagaataga
    17821 aaaagagagt gtgaaatcag ctagctatta ctaaaagcta gctgattgaa catcgttaca
    17881 ggaaagagtt tgagcctcac tcttagcttc gattcataag gagatgtgac ataaattttg
    17941 tcgcatctct tttttagtct actcttatta tgtaggagaa ggagggaggt ggatcatgta
    18001 tcaagagtca ataaagtagt tgataaaatc gttcctctct ctgtttcttt tctctttgtc
    18061 atacttttat ttttcttatg tgttctattt gttataataa aagagaaatg ggggaattgt
    18121 tgatgacgat tgaagaagca atagaatgga tccatagtcg attaccattt ggttcacgtc
    18181 ctggccttga ccgagtcgaa gctttattag aagtggtagg gcatccagag agaaaagtaa
    18241 aaacgatcca tatcgctgga acaaacggaa aaggttctac tgtagcttat ttgagaagcc
    18301 tattagaaga ggctgggctg acagtaggta catttacttc accttatatc gaaacgttca
    18361 atgaacggat cgcaatcaat ggcaaaagca ttccagacaa tgatttgatc cagcttgtaa
    18421 aaaaatatca gccactgatc aaacaacttg atcaatttga agcagtagct ggtattactg
    18481 aattcgagac attaacagca atggcatttg attatttttt gatgaagaaa gtggacgtag
    18541 cgattatcga agttggctta ggcggcttat tggattctac caatgtagct gtaccaatgc
    18601 tgacgggaat aacaacgatt ggacttgatc ataccgaaat acttggagat acaattgaag
    18661 aaatcgctgc acaaaaagct ggaatcatca aacaaggcgt tccagtagta acaggaaata
    18721 ttgccccaga agcttttact gtcatccaac aaacagctaa agcaaaaaat gcaccgcttt
    18781 atgtatacgg ggaaaattat aaaataaact atctgcatcc tgatgagatg tggggagaag
    18841 tatttgaatt ttttaatgaa ataggaaaga tccctcaatt aaccactccg cttttagggc
    18901 aacatcaagc tgaaaatgca ggagtagcca tcgaattgta ttttgtttac tgtcaattgg
    18961 aaaagctgcc tttccgagaa aaagatgttt tgaagggatt gaagaaatct cgatggccag
    19021 gaagaatgga gcgtttgagt aacgagccat tagttgtttt agatggtgcc cataatacgc
    19081 atgcaatgaa ccggcttgtt gagaatttga aaaaagaatt caaaggatat caaatcaaca
    19141 ttttgttttc cgccttacga actaaaaatg ttagagaaat gctagaacga ttgcagcaag
    19201 taccaaatgt ccatatttat ttgacgacct ttgaacatcc aaaagccatc gaattaagtg
    19261 aagtatcaga tttagcaagt gagagagtat caatcgtttc attgtggcaa ttcggattag
    19321 cagatatatt ggaaaagatg acaaatgaag acgtattagt tgtgaccggt tcactttatt
    19381 tcatttcaga agttcgccat ttattaatac aattaggagg agatcatgaa gtataatgca
    19441 gtgatttttg acatggatgg tttgctgttc gacacagagt tagtgtatta cgaagccaca
    19501 caagtagtag cagacaagat gggttttcct tatgataaag acctgtattt aaaattctta
    19561 ggtgtttcag atgaagaagt atgggcgaat tatcatatga ttttctcgga atttggcaaa
    19621 acaagtgtac aaagattcat agatgattca taccaggaaa cgcttgaacg tttttcgcaa
    19681 ggagcggtac aaatgaagcc cggtgtgttg gaactcctct cttttttaga agaacatcag
    19741 attcccaaag ttgtcgcttc cagtaaccaa cgagcagtca ttgaactttt attgaagaag
    19801 aacaatctgt ttgaacgatt tgagacgatt gtttctgcag aaaatgttca acgagcaaaa
    19861 ccagacccag aaattttctt gttagctaat cagaagctag gtacagcgaa gaaagaaaca
    19921 ttgattttag aagattcaca aaatggtatt ttagcagctt ctgcggctga gatcccggta
    19981 gtcatggtac cagatctgct tccaccatcc caagaattga tcaaaaaaac agctggggtt
    20041 gtttcttctt tacatgaaat ccctgcattg ttaaaataaa aatccatctc ttttcgtatc
    20101 ttattttaga taagatagaa aggagatgtt tttttgggaa aacgattgat caaagaagta
    20161 cctactagct ctttaccaag ggaacgtatg gaaatttatg gcgcggaagc tttatcggat
    20221 caggagcttt tggcaatctt actgcgtacc ggtcaacacc cttatagtgt gatgtcgatt
    20281 gctggaaatc tgttaaaaac gtttggagga ctggcctctt tacgacaggc tactttgcat
    20341 gagttagaag agattcgagg gataggacgc gtgaaagcaa tcgaaatcaa agccttgatc
    20401 gaattaggtc gacgaattca gacggatcat gaaagagcgg ctccaccggt tcgtaccagc
    20461 tacgaattgg cccagcaatt gattctggaa atgaaagatc acaaacaaga acatttggtt
    20521 tgtatttatt tggacacgaa gaatcaagtg atcttaaaaa aaacagtgtt catcggttcg
    20581 ctgaatcagt cagtcgctca tcctagagaa attttccatt atgctgtacg ttattgtgca
    20641 gcaaggatcg ttttagcgca taatcatcct tctggtaatg ttattccatc gcagcaggat
    20701 atgaatttta ccaaaaggat acaaaagtgt ggagaaatga tggggatcac tgtactggac
    20761 cacttgatca tcggacgcaa acgatatttt agtttgagag aagaaggaat gatggaagag
    20821 aagtaagttg ctttcttgca aaaaaaatga agcaagtgta caattatatt gtaattttgt
    20881 ttgggaatag aagttgaaac atctgttgca cctctatcgt acacgagcaa tgttacaatt
    20941 taaattagtg cttttggcac gaggaggata ttattatgga aaacggaaca gtaaaatggt
    21001 tcaacgctga aaaaggattt ggatttatct cacgtgaaga tggaagcgac gtattcgttc
    21061 acttctcagc tatccaaggt gacggattca aaacattaga agaaggtcaa gcagtgactt
    21121 tcgacgttga agaatcagac cgcggcccac aagctgcaaa cgttgtaaaa gcttaatttt
    21181 atctgtaaat caaattgatg gtagacatca atttttacga gagaacaaag cgagtaacaa
    21241 aaatacctgc cacaagagac aatttctctt gtggcaggta tttttttgta tgaaaaagta
    21301 aataaattta agaggctatg aaagagccac cttgtatcaa ggaataagaa caaacaaaaa
    21361 tggcttctca tgtttttcat ttgttttctc ttatattcag gacaaggtgc tgatttcata
    21421 acctcttatt tattcttcat ctggtgtcat taccattggc aaaatcattg gatgtctttc
    21481 tgtacgttcg aataagaaag gctgaagcgc gccagtcatc gcttctttca atttatattc
    21541 tgaacagtca ggtccattca aacattctct taaagcgtgg aataagattc gctgagcttc
    21601 attgatcatt tctcctgatt ctcgcatgta gacaaatcca cgagagagaa tatctggacc
    21661 agccaagatt tcttttttct tgatatccac tgtcgcgaca gctaatacaa gaccttcttc
    21721 tgaaagcagg tgacggtcac gtaaaacgac attaccaata tcaccgatcc cgctaccatc
    21781 gatatacaca tctccagcca caaaatgccc agcaggacgc gcagaatcgc tagttaacgc
    21841 taaaacatcg ccattttcca tgatgaagca gttttctgca ggaacaccta catcttgtgc
    21901 tagagaagca tgtactttca acatgcggaa ttctccgtgg acaggaataa aatattttgg
    21961 cttcatcaaa cgaagcatta atttttgttc ttcttgtcca ccgtgaccgg aagtatggat
    22021 gttattgatt tttccgtgaa tcacttctgc accagcttca gacagcaaat tgatcaaatg
    22081 attgacactt gttgtattac caggaatagg tgaacttgaa aagatcactg tatcgtctgg
    22141 ctggatttgg atttgacggt gagtaccatt cgcgatgcgg ctcaacgcgg ccatcgcttc
    22201 tccttgagaa cctgtacata ggatcatcgt ttcattggca ggcaagcgat tgatttcgtg
    22261 tgcatctaca aatgtgccgt ctggaacttt gatatatcct aaacgttgac cgttgacgat
    22321 ggcattttcc atgcttcgtc cgaaaacagc gattttacga ccagttgcca cagcggcatc
    22381 tgctgcttgc tgcaaacgga agatgttaga agcaaagctg gcaaaaatga tacgtccttc
    22441 gatttttgaa aagatcttca aaatagaatg cccaatcgtt ttttctgatt tagtaaatgt
    22501 tggaatctca gcatttgtac tatcagataa aaggcacaag actccttctt ccccgatacg
    22561 agccatttta tgcaagtttg ctggttcgcc aacaggagtg aaatcgaatt tgaagtctcc
    22621 agtcgctacg atatttccag aaggtgtttt caccacgatc cctaatgcat ctgggatact
    22681 atgggtcgtt ctgaaaaagc tgacagaagt ctttctaaaa cggatgatcg tatcttcatt
    22741 gatctcatgg agctctgcat ctcgaagcaa gccatgctca tctaatttgt ttgtgatcaa
    22801 cgctaatgcg agaggaccag catagatagg aatatttgct tgtttcagca agtagggtat
    22861 tccgccgatg tggtcttcgt gcccgtgagt aatcaccaag gcttttactt tgtgtaagtt
    22921 ttgtatgatg tagctgtagt cgggaatgac atagtcaatt ccaagtaaat cgtcttccgg
    22981 gaatttgatc ccggcatcaa tcaaaatgat ttcatcttgg aattgtaccc catacgtatt
    23041 tttcccgatt tcacctaatc caccaatagc aaagacgcct gtctcgttat ttttgatgga
    23101 aagtttcata ttaaaactcc actaatgaga aatcagcatt ttctttttcg tactctagat
    23161 gacttccttc tagaagttga acgaattcaa tattgtatgg ggtattttct tccacacgtt
    23221 ggcgagcgtc tacatcgctt tttgcctcaa tgtaaagaga ttttgtttct tcccgtttag
    23281 ggttgcgtac ttttgtttct tgataataaa ctttatagat cattgttttg tctcctttat
    23341 ctgcgtaaag cagtgattta gctagttgat ttttttagac aacacaaaac gaggggacaa
    23401 gccacctggt ttttcatatg ctttgactag aatactggat tcgagtcaaa gagacaagcc
    23461 tcgtttttgc ttatctgttc ggatattttt tcaaccgtac cttctgtata aaaaatatac
    23521 aacaattaat tgttattcta gcataaaaca gcaaataagt atagaaatca actagattga
    23581 aagaaaaaat caatgtttat catcccgcta taatcataat gactttttta tgagagaagt
    23641 gttctattaa taggctcgtt gtgctatcat ttttagtaat gaaaatgtaa caaaagatta
    23701 aaaggagatg agaaagtgaa actaatgtgg cattatacca tgcgttataa gaaattcttg
    23761 tttttcaatt tcatatgcgt atttggtttt attttgattg aattaggact tcctacgatt
    23821 ttagcacgta tgatcgatgt aggaatccgc aatgatgatt ttgattatgt gaagcaacaa
    23881 gggatattta tgatcgttat tactgtaatc ggtattattt tgaatatctt gttaggttat
    23941 tttggttcga ggattacgac taatatcgta gcagatattc gagatgattt gttcgaaaag
    24001 atccaaagtt attcgcatca ggaatacgaa aatctaggcg tatcttcatt gatcactcgt
    24061 acaacaaacg atgcttatca gatcatgttg ttcctgcaaa atattttacg tatcggtttt
    24121 atggcaccaa tgatgttcat tgtcagtttg tacatggtca tgcgtacaag tgtgacactc
    24181 agtttgtatg tagtaggtgc attaccttta ctattattgg cagtcgtagc gattgctaag
    24241 gtgtctgaac cgttatctaa aaagcaacaa aaaaacttag ataaaatcaa cagtatcttg
    24301 cgggaaaatc tttcaggatt gcgtgtgatt cgtgcattcg tcaatgaaaa gtttgaagaa
    24361 aaacgttttg ctgtagtcaa tgagaattat gcttctagtt caaaaagctt attccgtttg
    24421 atggctgttg cacaaccggg tttttatttc ttatttaata tcgtaatggt attgatcatc
    24481 tggagcgggg cagtgcaaat cgatgcaggc gagcttcgtg taggagattt gattgcgttt
    24541 atcgagtata tattccatgc cttgttctca ttcatgttat ttgctagtgt gttcatgatg
    24601 tatccaagag cagctgtttc agctggacgt atccaagaag ccctagatgc caaaccttcg
    24661 attgtagaag atccaaatgg tatatctgat acaaaaacta aagggtatat cgaatttcaa
    24721 aatgtaacat ttgcttatcc aggccattcg caagagccag tgatacgaaa tgtcagtttt
    24781 acagcctctc caggagagac cgttgctttt attggaagta ccggtagcgg aaaatctacg
    24841 ttgatccaat tgatccctcg cttttatgat gtgagtgaag gaaagatctt gatcgatgga
    24901 gtagacgtga gagattatcg gctaagcaag ttgcgagata agattgggtt tattccgcaa
    24961 aaagcgctgc tatttactgg aacgattgca gataatttgc gatacgggaa agaagatgct
    25021 acgcaagaag aaatggaacg tgcagctgag attgctcaag cttcagaatt catttctcga
    25081 aaaccagatg gatttaatga acatttatca gaaggtggtt ccaatttttc aggtggacaa
    25141 aaacaacgat tggcaatagc cagagccatc atacgccgtc cggaaatcta tatttttgat
    25201 gacagctttt ctgcattaga ttatcaaacg gatgcgaagt tacgtgctcg tctgaaaaaa
    25261 gaaacgacag aatctactgt attgatcgta gcacaacgtg tgggaacgat catgcatgca
    25321 gataagatca tcgtattaaa tgaaggagaa gtcgtcggta tggggacgca tcgggagttg
    25381 ttggaaaaat gcccgattta ttatgatatt gccgcttctc aattatcaaa ggaggaatta
    25441 gcatgaaaaa aaccttttct tccttaaaac gtttagctcg atatatcaga ccgtatcgtg
    25501 agacttttct tttagtgatc ctatttacag ttctgacagt ggctttcaac gtggctttgc
    25561 catatgttac aggacttcct actacagaaa tcagccgtaa tattgccaat ggcgaatcaa
    25621 tcaatttttc ttatatattc aaatgtctca tttggatcac agttgttgga atagggtatt
    25681 gtatttcgca attactttct ggtgttttga tgacaaatgt cgttcaaagt gccatgcatg
    25741 atttgagaag agacatagaa gaaaaaatca atcgtcttcc ggtttcatat ttcgataaaa
    25801 accagcaagg aaatattttg tctcgtgtga cgaatgatgt agatgcagtc agcggtgctt
    25861 tacaacaagc ttttattggt atcgtaaatg cgatattggg aattacgttg gctgcagcaa
    25921 tgatgtttta tatccagccg atgatggcgc tgatctctat gatcatgatt ccaacatcga
    25981 tctggatctc aaaacgagtg atcaatgctt cgcagaaata ttttcaaagc atgcagaatt
    26041 ctcttggtga gctaaacggc tacgtccaag aaaatatgac aggttttagt gtattgaaag
    26101 tatatggacg cgaaaaagaa acattggaag gattcaaaaa agttaatcac agcttgaaat
    26161 actttgggtt tcgtgcagca ttcatttctg gcttgatgat gcctctagtt caattaactg
    26221 cctatgctac ttatattggt atggctgttc taggaagctt ttatgttatt actggggcga
    26281 tcgttgtcgg tcaactacaa gcattcatcc aatatatttg gcaaatcagt cagccaatgg
    26341 ggaacgtgac acaattgtct tcagttttgc aaagtgcatc agcggcaacg aaacgtgtat
    26401 tcgagatttt agatgagcca gaagaaaaag aaaacaaagt agatgcttca ctgccagaaa
    26461 cgattttagg agatgtgaca ttcgatcatg tcgattttgc atatgatccg aagaaaccat
    26521 taatccaaga tttgaatttt gaagtgaaag ctggtcaaac cgtagctgtg gtcggtccga
    26581 ccggtgccgg caagacgaca ttgatcaatc tattgatgcg tttttatgac gtagacaaag
    26641 gagcaataag gattgatgga atcgacacca aatcaatgag tcgcagtgat gtgcgttcgc
    26701 tatttggtat ggtcttgcaa gatgcatggc tttatcaagg aacgattgca gataatatcc
    26761 gcttcggaaa gcttgatgcg acagattatg aagtagttga tgctgcgaaa acagcaaacg
    26821 tagatcattt tatccgaacg atgccagatg gatatgatat ggccatcaat tctgagggag
    26881 acaatgtgtc tttaggacaa aaacagttgc tgacgattgc ccgagcagtg gtctccgatc
    26941 ctaaaatctt gattttagat gaagcaacaa gttcagtaga cacccgttta gaagcgttga
    27001 ttcaaaaagc aatggatcgc gtgatggagg gacggacaag tttcgtcatc gctcaccgtt
    27061 tatcgacaat ccgtgatgca gatctgattc tagtgatgga tcaaggtcag atcattgaaa
    27121 aaggaacgca tgagagttta ttggcacaag gtggatttta tgaaaaactg tataacagcc
    27181 aatttgctga ggaagcagaa taagtcatat aagaataaaa cagtttaaaa cttatttttt
    27241 gttctctatt cttgataatg gtaaagtaaa gttatcaaga aaagtgagga cacggagatg
    27301 gaacagtttt taaatgaaaa aattactgaa gccaaaagag aagttgatcg tttaacgcac
    27361 gtctgtcaga cgaagccttt tgattcagct gatttttttg aaaatgagtt tcaaatcgaa
    27421 cgcttggcag cacaaataga agtgtacgaa ttaattttaa aaaaagtaat agaagaaaat
    27481 atagatgtac aataaaaaca ggtaaaacgt cagttaccag atactgtaaa tagacatctg
    27541 gcctgagcag gttttacctg ttttttttct tatgaaataa atatatgcta tgataccttt
    27601 attcaatagg attagtttct acaaaaaatg aaaggagaaa aataaatatg gaacggttta
    27661 tagcatcaaa tgccacagtg attggtgatg tgacattgtc agaagatgtg acgatctggt
    27721 atcaagctgt tttacgcggg gacagtaatt ggataaaaat aggacaaaga acgaatatcc
    27781 aagatggtac aatcatccat gtcgatcatg atgcacctgt agatattgcg gagaatgtga
    27841 cggtaggaca tcagtgcatg ctacatggct gtacaatcga aaaaggggcg ctgatcggga
    27901 tggggaccac gatattgaat catgcggtta ttggtgagaa tagtttgatt ggtgctggat
    27961 cattagtaac agaaggaaaa gttattcctc ctaatgtctt ggcttttggt cgcccagcta
    28021 aagtgatccg tcctttgaca aaagaagaaa tacaaaaaaa caaagaaaac atccagcatt
    28081 atgtcgagat aggtcggatg catgcgcaag gaaaattcaa ggagcaaaga taggcagtag
    28141 catccataaa ataaaaaagg atggtcagtt tgagttgacc atcctttttt atttggttta
    28201 gataagagag cttaaaaaag cttcctttga aacagattaa tttaatgaag aactgttttc
    28261 catgacttca tcgatcaatc catatgcttt tgcttgttca gctgtcatat agttgtcacg
    28321 atctgtatct ttttcaatca cttcaagcgg ttgtccagtg cgttcagcta aaattttgtt
    28381 taagcgttcg cgtgtttgca aaatatggcg tgccgcaatt tcgatttcag ttgcttgccc
    28441 ttgagcgccg ccaagaggtt gatggatcat gatctcagca tttggtaaag caaatcgttt
    28501 accttttgta ccagctgtca gcaagaagct tcccattgaa gcagccatac ccataacaat
    28561 tgtttggaca tctgctttga caaagttcat tgtgtcgtaa atagccatac ctgctgtaac
    28621 tgaaccacca ggagaattga tataaagata gatatctttt tcagaatctt gagcgtctaa
    28681 gaaaagcaat tgggcgatga tcgaattagc aagatcatct gttacttggc cgcttaacat
    28741 gatgatacgg tctttcaata aacgtgagta gatatcgtaa gctctttcac ctcgtgaaga
    28801 ttgttcaatg actgtaggaa ttaaattcat aatagagttc ctccttgatt tcgtttagaa
    28861 atagtgtacc ataatttagt ttctaatacc taaaatgtag tatacatttt tggtcaaaaa
    28921 aggtcaaata aaaaacttag gcaaattagt cgcataaacc cgctttatgg tatgataagc
    28981 agagaaacaa aacaaggagg aacaacagat tgatagttgg tattactggc cttatcggag
    29041 tgctgacagg tgctgtagtt gtctatatcg gcatgatact gcaaatgcgt cacttggaaa
    29101 ataaagaaca gcgtagacgt gaattggaat tgaaagtcaa agaaatcgag acgctgaatc
    29161 aattaaataa aaagatcaac gagatcttgc aaaaacggac aacgctgatg gaagaatatg
    29221 tcagctttga tgcatttgat gattgttata tcacgattga cgattttgcg tatctccaat
    29281 cattttcagc gcaaaatagt ttttatctgc caaattatat tttagacgag ctatttaaga
    29341 atatctccca tcgaaaagtg attttatctc cagatgaaac aatgaagatt ggtggatatg
    29401 cttataaagg cggacgcgtg attttagaga attttacgga tagtctgact gaaatgatca
    29461 atgaaaaaaa agctcagttg aagactatga cgcgccagcc gattggtttc ttctcgaaag
    29521 atgatgtttg gagctgatat tttgaagcat tgccgttgca catgagagcg tggtaatgct
    29581 ttcttttttt cttaatgata caatagaact gaacggagtg aagaaagatg ttacaaatct
    29641 atgcccatcg cggaagcagc ggcacccacc cagaaaatac gcttcctgca tttgcagaag
    29701 ctgtacgagt aggtgcagat ggtatcgaac tagatgtcca tctaagcaaa gatggttatt
    29761 tgatcgttat gcacgacgaa gaagtggacc ggacgactaa cggtaaaggg ctgattcgag
    29821 aaaaaacatt ggaagaactc aaaaaattga atgcaggggg caaattcagc aaagaatttc
    29881 cagcagctaa agttcctgaa ttgagagaag tgttaggact gctcctccaa aaaaattacc
    29941 gagggatgct aatgattgaa attaaaactg atcagtatga atatcccggt atcgaagaaa
    30001 aattagccga aacattaaaa agtagagatt ggccttttca acatgcatat tgcagctttc
    30061 atttggattc tttggaaaaa atcgcattac tggaaccgga gatacagctg gacttattga
    30121 tgagtacttc tgataaaaag atccaactag cagcagaaac cccttatata gaaggagtac
    30181 atccaaaaaa tacttggttg ttcgaacatc cagtccaggc agctgatttt ccaaaagcaa
    30241 ttcgtgcatg gacgattaac gatgaagaag aaatggccaa atgtcaagaa ctcaaaatag
    30301 atggaataat aactgatttt ccggagaaag ctcttcggtg gaaacaatca acgaaaagta
    30361 ggtaaaatat ggaaaaagta ttagtgatcg tcggtccgac agcagtcggt aaaacagcgc
    30421 taagtgtgga actcgcacaa ctatttggag gagagatcat cagtggtgat tcattgcaaa
    30481 tctataaaaa tctggatatc ggtacagcaa aaatcaaaga agaagagatg aataatgttc
    30541 cgcatcattt gattgatgtg atcgaaccta ctcaacgtta ctcagccgct gattttcagc
    30601 attcaggtcg acaattgatt accgagattg cgaaccgagg gcacctacct atcatagctg
    30661 gtggtacggg tctctatatc caatcccttc tatatgatta tcagttagga gcgacagaag
    30721 aagcgaatcc tgagattaga aaaaagtatg aaacgttagc tgaaacaatt ggttcccaag
    30781 cattatggaa tcagttgaaa gaaaaagacc cggcagctgc tgagaaaatc cactggaaca
    30841 atcaacgcaa agtgataaga gctctggaag ttttagagac gacaggacat agtatcacgg
    30901 cacctaaaga agagccaaag caattgtatg attacctcat gattggatta gatacgaagc
    30961 gtagtattct ttatgaacga atcaatcaaa gagtcgattt gatgctagca gaaggtttag
    31021 tagcagaagc gcgtaaggtg tatgagcttg gagaagtcca ggccagtcaa ggtattggat
    31081 ataaagaatt tttcccttat tttgaaggga aagaaacatt ggaagaagca acagaacaag
    31141 tcaaactaca ttcgagaaga tacgcgaaac gtcagttgac gtggtttcgt aaccgtttgg
    31201 atgcacagtg gtttgatctt ataagtgagc caaatcaaaa aagtcagatt gagcaaacaa
    31261 tcaaaaaatg gctggaggcg gaataaaatg gaagaaaaag tgatcatcgt aggggtagaa
    31321 accgaagcaa accagcgtta cttttcagag tcaatggaag agctagttca gctgacgaat
    31381 accgcatcag gagaagtcgt attcacaatt acacaaaaga gaccacaagt ggatcggcaa
    31441 acgattatcg gtaaagggaa attacaagaa ttagttcaac aagcggatgc gcatgaagcg
    31501 gatttgatca tctttaatca tgagctaact ccgagacaga gccaactgat taccgatgct
    31561 gttggtcttc cggtaattga tcgcgtgcag cttatcttag atatttttgc gatgcgtgct
    31621 cgttcgaaag aagggaagct gcaggttgaa cttgctcagt tagaatacct gctgcctcgt
    31681 ttagtagggc aagggaaaac attatctcgt cttggcggtg ggatcggaac aagagggcca
    31741 ggtgaaacaa agttagaaac agaccgccga catatacgga ataaaatttt tgctgttaag
    31801 aaagaattga aagaagtaga agctcatcga gagcgcaatc gccaaaaaag aaaaaatagc
    31861 gagatttttc agattggact tattggctac acgaatgccg ggaagtcaac tatcttgaat
    31921 ctattgacac aagcggatac ttattcgaaa gatcaattgt ttgcaacgtt agatccattg
    31981 actaagagat ggcgttttgc tgaaggattt gagattactg taacggatac cgtcgggttc
    32041 atccaagacc tgcctacgca actgatcgat gctttccatt ctacattaga agaaagtcaa
    32101 aatatggatc ttttgctaca tgtagtcgat gctagttctc cagatcgtat tttacaggag
    32161 cagactgtct taaaattgat ggatgaactg aatatgaaag aaatgccgat actgactgtt
    32221 tacaataagg cagaccagat cgacccagcg atgttcacgc ctacgctatt cccaaatgta
    32281 ttgatttcta ctcagacgaa agaaggtaag atggcgttga tcgaagcaat caaacgtcag
    32341 ctgatggaac taatgacccc ttatacactt tctgtgccaa gcaacgaagg acagaaatta
    32401 agcgagttga gaagacaaac aatggttttg gacgaagcgt acatggaaga aacaaacgaa
    32461 tatgaagtta aagggtttgc aaaaaccaat tcaaaatggt taagaaaaaa ccaataaaat
    32521 tttatttttt taa
//
LOCUS       DAFENC010000031        30563 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.031, whole genome shotgun sequence.
ACCESSION   DAFENC010000031
VERSION     DAFENC010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30563)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30563)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30563
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.031"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(1421..2086)
                     /locus_tag="LP493_001820"
     CDS             complement(1421..2086)
                     /locus_tag="LP493_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2133970.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            2266..4248
                     /locus_tag="LP493_001821"
     CDS             2266..4248
                     /locus_tag="LP493_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HBL2133971.1"
                     /translation="MSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQ
                     LIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPY
                     SNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLFTDRFNQAFHTDYATNIFE
                     DFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQV
                     LWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVE
                     KIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHEPPKEIAGED
                     YHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRG
                     IKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEIS
                     EKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSMYLERNILSGEIYPPLKIK
                     IGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFF
                     LLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREP
                     KYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            4252..4890
                     /locus_tag="LP493_001822"
     CDS             4252..4890
                     /locus_tag="LP493_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2133972.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            4918..5346
                     /locus_tag="LP493_001823"
     CDS             4918..5346
                     /locus_tag="LP493_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133973.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            5803..6714
                     /locus_tag="LP493_001824"
     CDS             5803..6714
                     /locus_tag="LP493_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBL2133974.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            6931..7368
                     /locus_tag="LP493_001825"
     CDS             6931..7368
                     /locus_tag="LP493_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133975.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            7463..8347
                     /locus_tag="LP493_001826"
     CDS             7463..8347
                     /locus_tag="LP493_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBL2133976.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            8571..11738
                     /locus_tag="LP493_001827"
     CDS             8571..11738
                     /locus_tag="LP493_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133977.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            11758..12303
                     /locus_tag="LP493_001828"
     CDS             11758..12303
                     /locus_tag="LP493_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HBL2133978.1"
                     /translation="MNRIWNKSHRNNCSLLMILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILI"
     gene            12331..12786
                     /locus_tag="LP493_001829"
     CDS             12331..12786
                     /locus_tag="LP493_001829"
                     /inference="COORDINATES: protein motif:HMM:NF023225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
                     /protein_id="HBL2133979.1"
                     /translation="MKLKKAYADQSDGRNVIKANLQNPNASYMFGLTTSVEIYKKETK
                     EPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKGAWKEKRWNLHTDFEITD
                     DAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFILKERRKKK"
     gene            12783..13541
                     /locus_tag="LP493_001830"
     CDS             12783..13541
                     /locus_tag="LP493_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBL2133980.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(13627..14367)
                     /locus_tag="LP493_001831"
     CDS             complement(13627..14367)
                     /locus_tag="LP493_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2133981.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            14428..15681
                     /locus_tag="LP493_001832"
     CDS             14428..15681
                     /locus_tag="LP493_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBL2133982.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            16003..16230
                     /locus_tag="LP493_001833"
     CDS             16003..16230
                     /locus_tag="LP493_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003246265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBL2133983.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            16353..16679
                     /locus_tag="LP493_001834"
     CDS             16353..16679
                     /locus_tag="LP493_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBL2133984.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            16747..17460
                     /locus_tag="LP493_001835"
     CDS             16747..17460
                     /locus_tag="LP493_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HBL2133985.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            17770..18620
                     /locus_tag="LP493_001836"
                     /pseudo
     CDS             17770..18620
                     /locus_tag="LP493_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            18741..20606
                     /locus_tag="LP493_001837"
     CDS             18741..20606
                     /locus_tag="LP493_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL2133986.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            20654..22063
                     /locus_tag="LP493_001838"
     CDS             20654..22063
                     /locus_tag="LP493_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBL2133987.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            22171..22872
                     /locus_tag="LP493_001839"
     CDS             22171..22872
                     /locus_tag="LP493_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2133988.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            23031..23510
                     /locus_tag="LP493_001840"
                     /pseudo
     CDS             23031..23510
                     /locus_tag="LP493_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            24358..24933
                     /locus_tag="LP493_001841"
     CDS             24358..24933
                     /locus_tag="LP493_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HBL2133989.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            24933..25373
                     /locus_tag="LP493_001842"
     CDS             24933..25373
                     /locus_tag="LP493_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBL2133990.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            25389..26090
                     /locus_tag="LP493_001843"
     CDS             25389..26090
                     /locus_tag="LP493_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBL2133991.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(26578..27003)
                     /locus_tag="LP493_001844"
     CDS             complement(26578..27003)
                     /locus_tag="LP493_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133992.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            27377..28348
                     /locus_tag="LP493_001845"
     CDS             27377..28348
                     /locus_tag="LP493_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2133993.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            28380..29777
                     /locus_tag="LP493_001846"
     CDS             28380..29777
                     /locus_tag="LP493_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL2133994.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            29936..30559
                     /locus_tag="LP493_001847"
     CDS             29936..30559
                     /locus_tag="LP493_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2133995.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
BASE COUNT        10371 a         4963 c         6286 g         8943 t
ORIGIN      
        1 ctttcgaacg agatgatctt gaggaactag atcatcaatc gtaagcatcg caaattgatt
       61 tctaccattc gtattgtttt tagacatcat agctatcact ccttgcattc gttttcataa
      121 atctattata aaagaaaaga ctgtagatat catccataaa atggactttg tctacagtct
      181 gaggactacc tgtattagtc ctcttttttg accagatttt gaccagtcta ttttacattc
      241 taatatattc atatgagcta attttatgat taaatggtaa gtgtttcctt gtttgtttta
      301 gtttaaacta gtgtgtaatt taaaaatcta tatggaaggg tctgtggggt aatacttaaa
      361 taaaggctag gaacctgata acatcaaggt tcctagcctt tttataataa aatgaagcga
      421 aaataatttc ttttaaagag ccgagattat cagctatata agagtgaatt tgatgcaaaa
      481 aacagagccg aaacagtctt ggtgttcgta gctctgctta tatgtttcga atttaagaca
      541 aagagttggc aaaagatgtt gataaggaag ataagataac tgtgttatat aaactaggta
      601 actaactgta acaagctaat tttaagagat tcttattaga agacgtttag gaatataact
      661 aagaaaatga ttatacaggt aattgtcatt tcaataatgt tttctaattt tcgcgtcttt
      721 gttttaagaa aaaggccaga atcagttgga aaaaagttcg tacgatagtg aagaggggca
      781 aaatttccta ctaatattcc cactaacaag agataaaacg gccaggttgg tgtgattcct
      841 ctataaaaaa atgcccatgc taccgaaatc ccatagatta acaactgaac aatttttaca
      901 atgaaaaaat tgttctgcca ttactcaaag tctcttcctc cttgtatcgt ttatttgttt
      961 cattttatca ttatgatagg cgcttgaaca atccattttg tattttattg agtactcttg
     1021 gataaactac cagcgattat catatttatt tatgttactg taagccatca tataaaagta
     1081 aatgagcaga tcatagaaat ataaaaaaga actaaaattg atctaaatta tgtgcagctt
     1141 gactacgtac caatctatat tacttactag attggtcgtt aatctattcg gatcgaatga
     1201 gcaaaatatt tttgtgaatg tccatccttg attatgattc caaaaagaat cattgggagg
     1261 ctgtggcgta aatattatac tataagccag aaatacctat cattctgaac ttttttattt
     1321 aggaactttc atctcaaggc tttttcaatt aatttgtacc cctgtttttt ggataagatc
     1381 atgtgcattg attttttcta tctctacgtt catctcctac ttaatgccta tctggctcct
     1441 gagggcttct ttttaaggcg tcgtcatagt cttggctgag gatttcttgg taatctgagg
     1501 gaatggcttc ccaagtgagc aggcgaacgt tcatgacgtg ttttcctttg tgtttgatta
     1561 cagcatggtt tttctctttt tctacctctc cagcgtgaaa agacagccat gtaccatggc
     1621 caaagatatc attacatacc caacgttcga tggaattgtc cacgtatcct acagggagtg
     1681 tggtatagcc gatttgtggt ttcaaaaaag gattgaatcg atcgatcgtt tcatttttgt
     1741 attgataatt gataagaaaa agatagacca aacaaaagac gagcagaaag aaagatagtg
     1801 tctttttgag tgagaagggt tgttttgatg aataagattt cttgttaaca agaggttcat
     1861 ctggcaatgt tggttctatt gattcggtag ctgattcaat agaaggaaaa tcaatcggca
     1921 gacctaaagt atgatgtaaa agtgacagca tttcaaggtc tggcattgta cgagaatttt
     1981 cccaactaga aatcgtttta tcggaaacac caattttttc gcctaattct ttttgcgtaa
     2041 gcttacaatt tctgcggtaa gttcgtattt tttctccggt gttcatcttc ttctcctttc
     2101 gattctacag tatatagatt tattctacat gacctataca cttgatagat acgttttttt
     2161 gatgaaaaac ggtatgattt tatcaaagaa tcatttaagt aagggagagt ggtgataatc
     2221 aaaaaaaagt tcacagtttt actcacaatc atagtgaccg gtatcatgag tggttttgcc
     2281 ttggttagta taaataaaca ggtactctat cggacaaatg aatttttcca tcaaacagat
     2341 acttatactc cgattcgatt gccacaacat tttattgggc aagaagaata tgagcagcta
     2401 atcatggtat ttgaaaatgt ctcatcagaa actgagcttt cttatatgaa aaaaacagta
     2461 aatgaatcca atgaagtaga tacatcttgg aacttcaaga tacagccaaa gcttgaaatg
     2521 acattgtatt atcaagggga tgtcaaatct tctcacgaga aggtacccta ttctaatacc
     2581 tcctttcgcg taacgtccat tgaagaatcg atcaaaataa aagattttga aggtgaattt
     2641 ttcttgatga cgagagaaaa agaagcctat gaacggttca tttcactatt cactgatcga
     2701 ttcaatcaag catttcacac tgattatgcc actaatattt ttgaagactt tgaaaatagc
     2761 tattcgtatt cggttatttc aaatacagac gtatataatt atcgagtgta tttaactatt
     2821 ggattgattc ttttattcct tttgttatca tcctttttct tattgatgaa taaagaaatc
     2881 agtttattgt tgaataatga cttttcatta catcaagtat tgtggtgttt attggggaaa
     2941 aagaaaatca ttattacatt cataattgca ggaatcattg gtggttttat ttttatgtat
     3001 tataaggagc aatttcttta tttgttccag atgtacgttt tcttgttcag cggaatatat
     3061 ggtatctctt tgatttctct tttattagtt gaaaaaatcg cttcgttaag agaagcgttc
     3121 aactatatcc aatacattct ttttacattt ggattgttgt tttctcttct tttgaccgtt
     3181 gccaatgtcg aattagcaac tatcgttttt tcttcttcac agttagctgt ttcccatgaa
     3241 ccaccaaaag aaatcgctgg tgaggactat catgtatttt atccagtaac catcgggaaa
     3301 aaccacgtgg attttattta ttccaatcgt tttgcatcag cagcagatca ggaattatat
     3361 gaaactttga ataaaaacgg aagtatatta gtcaatgtat cagattactt gaatgaagaa
     3421 aatgaacagt ttggcagagg gataaaaata aatctgaatt atcttaagaa atttcctttg
     3481 attgatgtct ctggaaggtt gatccaaata accgaaaaag aaacgcaccc tgttatattg
     3541 atccctgaac gatatagaca tacagattta aaaaatgacc tggcgcaaat aacagaatat
     3601 tatcaagaaa tcagtgaaaa agaaccgaaa tttctattta taaaaaacaa tcaacccatt
     3661 tatacattta ttccttctat cccctggatc gaacattatc cggttgttga aatactgaca
     3721 ttgaaaaaca gtatgtattt ggaaagaaat attctcagcg gagaaatcta tccaccgtta
     3781 aagatcaaga taggctcttt gtcgaaagaa aggttatttg agctgattga agaaagtcag
     3841 ttacgtgata acttgcagtt atcatttccg tatactcaga ctgaagagat agctgtcaaa
     3901 gtgttaagca gatcatttca ttacttgata cagatatttt tactcacttt cttttctttc
     3961 ttcttgttga gctatgtcat gttatgcata tattttgtct acaattgtcg gaaaatcgct
     4021 atctttcgtt caagtggtta ttcgctcttt gaaacgtata aagatttctt catgatgaac
     4081 ctcatcaaat ggggaacgac aagtgtaatc ttcctttttc ttatagaaag agagcctaaa
     4141 tatcttttta atattttttt ctttagcttc attgatttta ttctttcagt tgtttttatt
     4201 ttgtctacag aaaagaaaag tcagttattg ctgatgaatg gaggttaaca attggagccg
     4261 ttgatagtga taaaaggtgc gaaaaaaatc attcgaaaca aaacgattct tcatttggat
     4321 cgtttcactg cggatgctgg ggatcttgtg actgttgttg gagaaagtgg agcaggtaaa
     4381 agtacgttat tgaatatatt aggattgaat gatcagttca gttcaggaca attctatttg
     4441 ttcgatcaag agacgaaaca attaactggg agagagaagc gcttgataaa aagaaatacc
     4501 atatcttttc tttttcaaga ttttgggttg attgaatatg aaacaatcga ttttaattta
     4561 gatattggat tgaagttttc gaatttaaat gtttcagata agcgaacagc aaagtatgag
     4621 gcattgaaaa aagtaaatat aaacaagaag ctaagtacgc ctatctacac attatctggt
     4681 ggtgagaagc aaagaatcgc ctgtgcgaga gtcttattga agaatagcaa aatcatttta
     4741 gccgatgaac cgactgggtc attggataaa agaaataagg ataaagtagt tgaaatctta
     4801 tcgcaacaag cttcccaagg tacgttagtt atcgtagtca cgcatgatcc atatctgacc
     4861 aaaataggaa acaagaagat catgctttaa aaatcaaaaa ggaaaggatg tcgttttatg
     4921 aaaaaagcag ttattatttg tgcactaggg ataggttttg ttggaggaaa cgctatgtca
     4981 tctgaagtgg aagcaaattc agttcacggt gaaatctatt acaaatcttt aaagccagga
     5041 gagattcatt ttgatgctaa aggtaatatt attaagtcaa atttaccagt agaccgggaa
     5101 atttctagaa cagcaattaa tcatagctct ggaagatggg tttattatag tgatacaact
     5161 tgtacgagaa aaacaggtca ttctaaccac tatagtcgtg tctataatcg tcacggtgca
     5221 aaagcgaaag ttggaaactc tattcgatca gcaaatgcaa caaaaggagt atgggcctat
     5281 gcaagtgcga caggaaatag aactgacaca ttctcatgtt ggtacaatcc aaccggttgg
     5341 tattaagtat ccaaaagttt atataaaata gaaaaaacat ataatgaaac agcgttaaaa
     5401 gttatttttg gtagttttaa tatattcatt tttagttgta taaaaatata tcataataaa
     5461 aacaacaaaa aaatgtctgg aaaatcgaac ataaaagtgt ctgatttgaa tatcccagca
     5521 gcggaagaag aaaaacaaaa tcgataacat ttgttctaag aattagttac gttaaatacg
     5581 gaacgcaaga tagacttgaa aaacggtaac aaaagaagta gtatattaag gtgtgatgtg
     5641 ctacttgaca tttattctgc tgagcgaact ttctggattg tgtagcctta tatctattca
     5701 ggacgtatcg agcagattag taaaggtgtt cttgatgatt ttcatcttga acacctttgt
     5761 ttttagcaat tcgcaaaaaa cgaaaagtag gagaattgat aaatgaaaaa aagattttta
     5821 gcacttgcca tcgtactagg cactggctta ttgtcaggct gtacgaatgc cggtgaaaaa
     5881 acagccgtta gttataaagg cggtacaatc agcgaacaag aagtaatgga tagcttgaaa
     5941 aaaatgcaag gagcagattc cgctgtgcaa cagttgatcg tttatcaagt atttgaagat
     6001 aaatatggag atgacgtatc aaccaaagaa atcgattctc aatatgatca aacaaagaaa
     6061 caattgggtg attcatttga ttcacaattg aaatctgcag gttacacaga acaaacattc
     6121 aaagacagta tcaaacaaag tctagccttt caagaaggtc taaagaaaca tatcaaattg
     6181 accgatgaag atttaaaaac ggcttgggaa tctttccatc cagaagtgga agctcaaatt
     6241 atccaagtag caagtgaaga tgatgcaaaa gatgtgaaga aagctgctga taagggagac
     6301 gatttctcta aattagccaa agacaagtca actgatacta cgacaaaaga agatggcgga
     6361 aaagtgaaat ttgattccac tactacaacg gttccggcag aagtcaaaga agcagccttt
     6421 aagttgaaag atggtcaagt ttctgatgtg atcacttcta ccaatgcttc aacttatact
     6481 acggaatatt atgtggttaa aatggtgaaa aaccaaaaca aaggcaacga catggataaa
     6541 tacaaaaaag aattgaaaga aattgcaaca gacacaaaat taagtgacag taccttccag
     6601 aataaagtaa ttggcgaagt attgaaagac gctaatgtaa aaatcaaaga caaagacttt
     6661 gaaaatgttt tgagtacatt cacttcagat tctagtacag caagtagtaa ataagcggta
     6721 taaataaaaa atatgaacta tttaaatcaa taaaactgtt catctaaatc tttttattag
     6781 aactaaatca acagtagttt aattactact tgatttagtt ctttttattt taaaaatttt
     6841 ttttacttag aatccagcga ccctagatat ttttctgtat aatcttaaat aaagaaaaca
     6901 atatcaaaaa atgcacgtag aagtagataa atggagtggt tttgcaaatt tcttttattt
     6961 ctagaagtta ttcacgtata cggatttgtt tttctcacaa ataaaaaggc aggaagtaca
     7021 atggatcatt tgtatataaa atatattcat caattttccg ttttggtgtt aggcacacta
     7081 attatagcgg ggattgtcgc atttattatt caaggccgtg acatattaac agtacatcaa
     7141 gagtttttca gttatgcatt tggtattcct ctgatcgcta taaggtctga taacaaaaag
     7201 tggaagaaac gctattacat tctcttgcta tttttgtgtt tttatctgcc acctaagatt
     7261 tttactttat taggtataca atgcctatca ttttctttta tttcctatat cattgtttta
     7321 attttcctca gtttcatagt atggatgttt tatcttgtca aaaaataaat gaatgtttca
     7381 tgaacagtac ttcatcacag cctaattttt ttctttatgc tatcgttata ttaaagaaat
     7441 caatcagaag ggaaagaaag tgatgaaaaa agttttatta gtggtaaacc ccagttcagg
     7501 cggtgaacaa gcaaaggaat ttgagcaatt agcgatagca aaattggaat cggtgtttga
     7561 tgaagtggtc gtcttgcata caaaaaaagc aggggatgca aaaaacttta ctcgcgaagc
     7621 ggctacggaa gggtatcata gtgtgtttgt catgggcgga gatggaacag tcaacgaagg
     7681 aatcagtgga atcgctgaac aagaacatcg gccaaatttc ggatttttcc cattgggtac
     7741 ggtgaatgac ttggctcgag cattagggat accgctagaa cctgaggaag cgatcaatca
     7801 tttttcgatt gaatcagtca agccattgga tattggaaaa ataaatgacg actattttat
     7861 gaatgtcgtc gcaattggct ctatccctga atcaatcaat gatgtagatg cggagaagaa
     7921 gacgaaattt ggaaaactag cttatttcat gtcaggaatc aaacagttag cttccacaca
     7981 atcctactcg tttcacgtag aagttgatgg aaagaaggaa gaaattgaga gcagtacctt
     8041 gctgatagga ctaactaact cagtcggcgg ttttgaaaca ttacttccaa atgcaaaagt
     8101 ggatgatggt aagctccatt tggtttattt aaaagattct tctttgatcg atacgcttaa
     8161 aacattgcca gacctattaa aaggagtaga tgaatctacg aaaaatctag cctaccttac
     8221 ttgtgagcaa ttagttgtgt cattagctga tgaggaagaa ttgacgacga atgttgatgg
     8281 agatgaaggg gataaattac ctgtgacaat caaagtattg ccctcacatt tacaggttta
     8341 ttgttaaaat ggaggttgtg accgaggagt tggcgggaga acaccgcttg ttcgggataa
     8401 gggactgtga caagactttt gtcacagcct tttttttgta caaaaaagaa atttacacct
     8461 aatagaaaaa tttttccata aaaatacata ttttaaatat gaaagtacaa ttggaaatag
     8521 attaaaacga taaaataaaa ttgtcaaaac gtcagagagg atggtggaga atgaatcaat
     8581 gtgtaaaaaa gctgattgcg tcgattttgt ttgtcttccc tctcttgatg gtgacatccg
     8641 tttttgccga tgtagagaaa acaaacgaat caacgcaatc agagaatcaa agttttgaca
     8701 agactacttt ttcagaagaa tcgattactt ctgaaactac agaatctcaa agtgaggctt
     8761 ctactaataa aaggcaagaa gaaaataaga caagtgagac ctcagaagta gctgaacaaa
     8821 cgtctgatag cagtgaagcg gcactggcaa gagctgtttc agcggatggg tacagcgaag
     8881 ctgccacaac agaagaactg gcgcagcttc tcgcagacga atcagtaact aagatccgac
     8941 tgattcagcc tttgacttta gacagggaat tagagatcaa acgagatatc gttattgatt
     9001 ttggtggatt cgctcacaat ttcggcacac accatattta tatcaatgag atacctcagt
     9061 cgatcgagtt ccagaatttt aaaggaacag ctgcacatcc aggtggattg acaccaaata
     9121 tcgatggaaa tgccattatc attgcttata tgaccgattt ttggggaagc agatatcatt
     9181 ttacgggaga aataaaattt accgggacac ttgatttgta tgatgggtcc aaattaggac
     9241 tgatttacgc tcctcgtgca actgtcacat tagatggtgt ttccggtgtg ttggatgtcc
     9301 aaccagtgaa ggaaggactg aatgccgctc cgggtaaagc ctatttttgt agaagctatc
     9361 aattgaatgt gatcaatggt agtcaacttt atggaccgta tctagggaaa ttctacggtt
     9421 ttctagattc aggagatgag actggtagtg gaaaaacagc gccaggaatc catatcttaa
     9481 gcggttcaaa ggtctctctt gattatgatc gggcagatgg cgttagcgat gaaggagagg
     9541 cagtcgatac gctacctggt aatgtcatgt ttgaagtcag tggttcggga agcgaatttt
     9601 cggtaaatac aaagatcaat attaccaatg acaacaatcg cggaatcatc caaatgagag
     9661 gttcaggatc gaaagtcact gtatcgaatg gtgggaaaat caccatcaat acagcaacta
     9721 cgggcggatt tcgcttgcaa ggagattcta gtcaaatcca tgtatcaagt ggtggacaaa
     9781 tctcggtcaa aatggctgga gatgacgatc aacccgggaa caatgggatg cgttttgtag
     9841 gaaaaggcct ttctttgatc gtagaaggag ccggatcagt tatcgacatc gataagcaga
     9901 gtgggcgttc cagcgcagtt cgttttgaga atggtacgca aaagctgaca gtaaccaatg
     9961 gaggctcatt gagggtaaga aatacaggtg atggcaaatc ttacgtgaac agactcaatc
    10021 aaggaaatca agcgatccaa ttttatgacg cttctggttt tctagaaagt ccaggttcag
    10081 ctgattttac agtcactgga gaaaaatcaa atatcgatat acgcgcagat tccggagcaa
    10141 ctgtagatac aactggagat attgatttaa attttacggc aggtgaaaaa acttatttag
    10201 tcatggtcgg gaaaacaggg gaagataaga ccggcatcat cagtggggat gtgttgaatg
    10261 tggacttaga atctcctacc tattttgatt tccaaaacaa acggattgga agcgagacca
    10321 atggcatagg cggctgggta ttccaaggaa atggagattc ttctttaaag atcgcccatt
    10381 cagaaatcgc tttatggcga aaaacaggcg caacattcga taactttgaa aaagacccgg
    10441 attatttttc tgatatgaca gacttatcga tcaatgggac cgacttaggc aatttcgtat
    10501 caagccctag tgcaggttta acaaatgaat ttgctcagac aggtgccgga atgaaaaatt
    10561 ataatcgaat cagtgccaat aatcagctcc cgatgattga atccttaaga gtgccaacga
    10621 atgcagataa aaaaatctat gggcatgtcg ttgttcccga aggtgtcgag gcaaagccaa
    10681 gagatgcttg gacaggcgaa gtagaagtga ctttacgtat tacttacgca gatacgacga
    10741 aatcatctgt agaaattact gctctcacgc aaggacaaac agatgaaaat gaaggggcag
    10801 gatataaccc atggggagaa ggcgaacaag gcggcttgtt cgaagttcaa gtacccaatg
    10861 atgagagatt aaaaacggag gatcaagtgc aagttgttgc tgctaaaaaa gtaagaggtg
    10921 gccaagaagt gacagaactg gactctgcca aaacgacagt cgatgtgatt cctcctgaac
    10981 ctgctaattt aagtaccaca ttgatcaatg cagcttctcg cacgatcaca ggtacaggtg
    11041 aagcaggagc cttggtttca ttgaaaaaaa atcaagctgt tttgtcagaa acaactattg
    11101 atgatacagg ggaatttgtt ctttctatcc cagaaaatca actttttgca ggagatgtat
    11161 tagaaattgt attaaacgac caagcaggag aagctactgc taagggtgtg cagaacaagc
    11221 caagtaccaa cgatgaaatt gggaatcaca atccaagtga tacgccagtt gtttatcatg
    11281 atgccccgcc ttttgcacct gctacgaaga tcgtagtaga aggtggtctc tcatttcttg
    11341 ccccttccaa actcgatttt ggtcagatca aagcaactgg tttgacacaa gaagcatttg
    11401 gccaaatgga tatacaggaa aaattatgga tttatgatca gcgagaaacg aaaaatccgt
    11461 ggatcttaac gataaaatta tctcagcctt tcacaaatga tgcaggattt tctatgcagg
    11521 atgtcctata tttcaagaaa ggagaggagt atcaattagt gaatgaagaa gaactggaaa
    11581 ttgtcagagg acaaaattca acgaatgtgc aagcagatta ttcagaatat ttaaataacg
    11641 gtcgggcgtt taaacttgtc ttaaccaaag aaaatcagat agctggtaat tactcagcag
    11701 agataacatg gacattagca gatgcgccga cagaataaag atcaaggagg atgattgatg
    11761 aatcgaatat ggaataaaag tcatcgaaac aactgctctt tacttatgat ccttctcctt
    11821 ggattcatcc tttggcagac acctgtccat gcctccgaat tcaattttgc ggtagatttt
    11881 gaattaccgg ctaatcagat tgataagaac aaaacatata taaatgtaag gatggagcct
    11941 gggaaaacac aggaaatccc ctacacggtc tttaaccgaa cagataaatc agtaacagtt
    12001 gagacattga tccactccgc tacgacgaat tcaaacggtg tgatcgaata tggagaatca
    12061 aaaagtaaat ttgatgaaac attaagttat gatatgaaaa acttagcaaa aacagtggga
    12121 gaaataactg ttcctcctca aagtgcggtc actgagacac tttcactgaa agcgccagaa
    12181 aaagagctgg ctggtgtggt cgcaggaggg atcacgtttc aagaaaaaaa agagaacgtt
    12241 tctaacaaaa gtacagttgg tgtcgtcaat cagttttctc aagtgaaagc aatcttgatt
    12301 tgaaatagcg aaaaagagtc ttccccagat ttgaaattaa aaaaagctta tgcggatcaa
    12361 agcgatggaa gaaatgtgat taaggcgaat cttcaaaatc caaatgcttc ttatatgttc
    12421 ggcttgacta catcggttga aatctacaaa aaagaaacaa aagagcctta cctttcaata
    12481 aaaaaagaaa aaatagatgt agcacccaat acaaattttg atttacttgt cccattagaa
    12541 ggaaaaaaat tagctccggg acattatcaa gcggttgtga agggtgcttg gaaagaaaaa
    12601 cgctggaatc tccataccga ttttgaaata actgatgatg cagcggacca attgaatgaa
    12661 aaggatattg atttaaaaaa tcagccagaa acatttgact ggcgatggct gatacttgtt
    12721 ggagtcattc ttattggctt atttgctgga ttatttattt taaaagaaag aaggaaaaag
    12781 aaatgaaaaa aacaattgca ttaagtaccg ttctagctgg aagtctatta ttatgtacac
    12841 aaagtgtttt tgctgagaat aagagctcag ccactacaga aggaacgatt tctgtgacca
    12901 aaccagatgc tgcaaatcct gaagacgttg ttccagttcc tcctgttgat ccaaatgatc
    12961 ctgatactcc ttttacacct gacgaaccaa atcagggaac atccggatta ctgacgattg
    13021 accaagctcc agatcttgat tttggaacaa tcaagttagg tacagcaaaa acagtatatg
    13081 ctgcattaca aagcggaacg gacagtactg gagcacaaac acaagtacag aatttcgtac
    13141 aagtaacgga taaaagcgga aattatgccg gttggaaatt atcagtcaaa cgaacagaat
    13201 ttattggtac aacatctgat acgaataaac taactggttc aaaggtgaaa ttcaaaaacg
    13261 ccgtgattcg aaatagcgca actaatagca gtggaatgcc atctaccgtt tctggaactg
    13321 gcgctgaagg aatcgaaatc ccagcagatc aggcagtaga tctagtaact gcaggagcaa
    13381 atgaagggat tggcacatgg atttattcat taggagagaa tgtggaacaa gggagacaat
    13441 cagtggaatt atttgttcct gtatccaatt atgctgtaga caactacgtt tcaacattca
    13501 catggtcgtt aacagatgct cctacagaag aggaagcgta aaatcatatc aacgatttca
    13561 gggagtggag ccgattcaag gcccactccc tgaaatctgc tatgcttacg tctcagctct
    13621 tattcatcaa ctcgaagcag ttttttggaa gtcatggaaa cgttcctttg tcttttcaaa
    13681 gatctttcga ccaacgagta aggagtcacc gttgaaaaat tctaacacat aatgagcaga
    13741 atcaattttc tgcaattgcg ataagttgat acagtaagat tttaaaagta aaaagtaagc
    13801 atacttttct aactctgtct tcaattgttt taaagaagta ttcactaatt tatcttctgt
    13861 agttgttttg accataactt ggtttttcaa acctttgata ctttcaatat ataaaatttc
    13921 ccgaggatac aggacgagac ttccaccttt ttgatcaata aagattttat cgacatttac
    13981 gatctgctgt tctttccaat tgatctgttc tagcacttga cgaatttgtt cagataaatt
    14041 cctgtctttt ctgatatatc caatcggaag gattttccga ttgatgatct ctactgcaaa
    14101 attcgtataa gcggtgaaaa aaacaatatt actatgtgca ttttttttac gtatttgttc
    14161 ggcgacatca atacctgtga gtgattgctt caagtcgata tcgataaaga aaacatcgtg
    14221 attatcaata gtgcccaact ggatcaactg attgatttga gagatagaag tgagctgcac
    14281 gatattctcg atatgatgat tgaccaattc tctgatgatc cattcgctgt gaaactggtt
    14341 atcttctatg ataaaatact ttttcatatg caggctccta ttaaaaaaat atgtgtacat
    14401 tttgaaacaa aacaatggag gaataagatg gtcgcaacag tgacacttta tttgaccttt
    14461 actttgattt tagatttagg tatctattta ttcttttcga aacaactgct agtaaaaaac
    14521 agctttggtt gtatagcttt gatggtggtg acacttttac ttcctatccc taaagtgagc
    14581 tttccttacc tagttggctt attattgatg tttctttttt attttactac gaaaaacctg
    14641 tttatcagct gtttgatcag taatcttttt tttgctatca ctggactcag cttttttctg
    14701 gtttttgatc tgatggatta tttaggaaag agacatcttg gaacagcaag tttttttgca
    14761 ctacttatcg catttatttt ctatctatta gtaaaaagta tagacaaaca gacgagattt
    14821 ctcaacttgc tttttactta tccaactgaa cactattttg gaggtatttg tattttatta
    14881 agctggggcg tgatttactt ggtattggga agtgttcact tccgctcatc taattatctg
    14941 cttctatctc ttttgtcgat agtcatcagt tttttttctt tgtttttttc cattatgttg
    15001 atcagtttcc aagtaaaaga aagacaacat caggaatcgc ttcaactgta tcaaataaat
    15061 gaagaatatt accatcatct agaggaattc aaacatgatt ataaaagtct actgttttca
    15121 ttaaaaatta ctcttcagga aaataaaaaa gaaacgttgg aatttttaga aatattagaa
    15181 gatcattctg cagctatttt tgaaaaaccg caaatacaac agctaacaaa tattgtatcc
    15241 ccagctgtca ggggtgtctt tttaaaattt ctagaaaaag cagaatcgga gaaaatcccg
    15301 atccaagtag ttattcctgt cgaagtgaaa acaatcccga ttgatctggt tgtttttatt
    15361 cgctgtttat ctatttttat ttctaacgca ttcgatcatc gtgtagccga tcagagtccg
    15421 attacgatca atctgctgga agaaaaagag ggatcacgtt ttagtatagc gaacaaggca
    15481 aatccaacga atttgacgct atcggagatg gtcaaaagag gaaaaacctc taaaaaaaat
    15541 ggcgggttag gtctatacag tgcgaaaaaa atgttggatg tttacgaaaa tgcagaacta
    15601 aaaatcgaat tttcaaaaca gaatcactat ttttttgtag aaatgtatct ggcatctaga
    15661 aagagcaaat cagcctactg acttactgtc aaaggataag tttgaggaaa gtctacacgg
    15721 agatagagac aacaacacag catattcaaa agaaacagaa gcgtgatgac cgttgtcacc
    15781 cttctgtttc ttttgctatg tagttaaaca aagtagttga cacttccgct acttagtatt
    15841 agtacgaaag tatacttcat gatactaagt agataagaag tgaaaagcgg aacccacgat
    15901 cgtcaaaatg ctaactgctt tgcttacacc agataaaggg aagagcaata tcgcttattt
    15961 taggcgtgga gaagcaagca aatccctacg atcacaaaaa aaatgctgac ccagcagtta
    16021 agagagttag aacaagatga aagtatccat cgaaaagcct ataaccaagt cccgcctaaa
    16081 gtagagtact cgctcaccga agaaggaaaa tcattaagag agattctagt agcgttgtct
    16141 gtttgggaag aagaacgtat cgaaaaacaa aaagcctcaa gggaagaaga cacgctactg
    16201 catacacatg gtggctacct aaattattga ttttctatga catttatttt aaataaaaga
    16261 aaacaggagt ttttttaaaa gcatcatcta ttttttatgt aaaaaaatgg tatgattaat
    16321 caagtaagaa gtgattggaa gaaggcaagc aaatgaatag tatggaaaaa gtcaaccagt
    16381 ttagagatga acgtaattgg cgacaatttc ataacgaaaa agatttggct atctctattt
    16441 ctttggaagc atctgaattg ttagaacttt ttcaatggaa aacgccggaa gaagtaaaag
    16501 aaacacaatt agaacgaatc aaagaagaac tggcagatgt attgatctat tcatacatga
    16561 tggcagacaa ccttcacctg gatctagatg agatcattga agaaaaattg atcaaaaata
    16621 atttgaaata tcctgtagaa aaaagcgcag gtgtacgaaa aaaatacaca gagttgtaga
    16681 aatgtgtcat tcggctgttg gaaagagcaa aagaaaaaca gtaaaatgag tctggaggga
    16741 gagaaaatga aaaaaaaagg aaaagcaaaa agatggctag tcaatatcct cttgttcctc
    16801 ttgttattag taggactagc tttgattttc aatgaacaga tcaaggatta ttttgtcaga
    16861 gagacaggag ataaatatgc tatagcgaat gtaacaaaag aagatctgaa aaagaataac
    16921 gataaagatg tcagttttga ctttgatgcg gtagaaccaa tgacgacaga aggggtcatg
    16981 aggtcgcaaa tgagaggaac agatctacca gtgattgcta gtatcgcagt cccttcagtt
    17041 tcaatcaatt taccggtttt caaaggcttg gataatacgt cactacttta cggagcagga
    17101 acattatctc cagatcaaga aatgggaaaa ggaaattatg ccttagcaag ccatcgtgca
    17161 acgaaccctg aattgctgtt tacaccgcta gaaaatttag agatgggtgc caagatctat
    17221 ttgacagatt tagaaaatgt gtatacatac aaaacatttt ttaaagaaaa agttgctcct
    17281 acagataccc aattactgaa tgaagtcgag ggaaaagaaa ttgtcacact aattacttgt
    17341 ggcgacatgg acgccgtcac gcgactagtt gtacaaggag aactggaaag tgttacatcg
    17401 ataaaagatg cgacagatga tatgagatct gctttcaatc tagagacaaa aacattttag
    17461 gatactggga cataagtcgt tacagattaa aaacagccaa aggatatgaa tcgataagga
    17521 aaaaccaatt tgctgaaaaa aagagaaacg caaagaggtg catctctgat ttggttgttt
    17581 tctagataga cttgtgttcc agttttttta ttttttatat gaaaaggctt gcataaataa
    17641 aaattcgatg gtatgatgat tttgaataag aaatggattg ttactgtacg gcaggcaaaa
    17701 ccagaattca gctaagaaac agtaggcgaa ttctaggttt ttttattttt cttgagaggg
    17761 cgaagcaaaa tgaaaattga taaaattttg aataacaatg tcgtcatttc gaaaaatgga
    17821 ttcggggaag aagtcgtttg tatgggaaaa ggactagctt ttcaaaaaaa gattggggac
    17881 gagatttcgc cagaagcggt ccaaaaagaa tttgtttaag agattctttt gctaaaaacc
    17941 aattccagca gctgatggct gatattccgg cagaggagat cgaatgggtc aaacaagtag
    18001 tcgaactggc tgaagataaa ctaaaagttg aattttcgcc taatatttat ctgacattga
    18061 ccgatcatct tcattatgcg atcacacgag caaaagaaaa tatccaactg cctaatccat
    18121 tattatttga aacaaaaaaa ttttatccga aagaatatca agcagcgaaa gaggctcttt
    18181 tgttcgtgaa acaaaagacg ggtgtggaac tttctgagga tgaagccggt tttattgcct
    18241 ttcattttgt gaatagccaa caaggaaacg aagacatgca agtgacgatg accgctacca
    18301 caatggtaag agatatactg agtatcatca gtaaattctt cggcatcgtg ttcgatgaag
    18361 aatctttgaa ttatcagcgt atcattactc atctgcagtt ttttgcccag cgttatctca
    18421 aaggggaagg atctgacgag caagatgaat ttctctacgc attagttcaa ggaaagtatc
    18481 caaaagcgtt tcattgtgtc gaacggatca atgagtatct tcgacaaacg caaaaacagg
    18541 aaatggggat cgcagagcag atttatttaa cgattcatat tcaaagagta gtaagtgaga
    18601 aaaaaagcat ccaatcataa ggattgttac tgtatggcag gcaaaacctg gattgaaaaa
    18661 ataggttcac gaatgtttgt gactgttttt ttcaatctgg gtttttattt tttaaataaa
    18721 aaagaaagaa ggaaaaaaca atggataatc aagcagttgg tcgtcgtgta tgggaagcgg
    18781 taggaggaca aaagaatgtc aaaagtttag tacattgtgc tacgcggttg cgattcagat
    18841 taaaagatga atctttagca gatacgcaaa agttaaaaga agacccggac gtgatccaag
    18901 tcgtacaaag tggcggtcag tatcaagtag tgattggcag taatgtagca gatgtttatc
    18961 aatcgatcgt ggatgaggaa ggtcttgcag tttcggagga tggaaaagaa gagtccaaaa
    19021 atattttgaa tcgtctgatc gatattatct ctagtatatt tacacctttt ctaggggcga
    19081 tggcagccgc cggggtattg aaaggattct tatcattggc aacggtgatg ggctggctga
    19141 cagctgatag cggtacttat caaatattgt ttgctgcagc agatggtgtc tttaccttct
    19201 tacctgtcat gcttgctttt acagcagcta aaaagttcaa agccaaccag tttttagcag
    19261 tagcaattgc tatggcactt gtgtatccag ctatcacagc agttgctggt gcgggagaag
    19321 ctatcagttt ctttgggatc ccagtgattc tttcaccatc tggttatact tcttctgtca
    19381 taccaatcat tctagccgta tgggttcaaa gtaaattaga gccattcgta aaaaaagtga
    19441 ttccgcaatt tctgcaaatg attttagttc cgcttgtcgt tttagtagtg atggttccat
    19501 taacatttct tgctttagga ccaatcggga cggttgccgg taatgcttta ggcggtctct
    19561 tcaactcgat ttatggattt agtccaatcg tagcaggtct aatcatggga agtttatggc
    19621 aagtattcgt gatgttcggc atgcattggg gattcgtacc gatcatgttt ttgaatatcg
    19681 aacaatatgg gtttgatgta ttgatgccaa tgcttcttcc agccatcttg gcacaaggtg
    19741 gggctgcttt agctgtagca ttgcgaacaa aagatacgaa acttcgagca ttagggattt
    19801 cttctacagt gacttcgtta tttggaatca ctgaaccaac tgtgtatggt gtgacattac
    19861 ctttgaagaa accattcatt gccgcttgta tttctggagg tattggtgga gctattatcg
    19921 gattttccgg agtaaaagct ttctccagca gtttggtcag cttattgacg attccgactt
    19981 tcattaatac ggtggatggt gtagagtcaa atgtgacagt agcagtaata gctacaggaa
    20041 ttgcttttgt tcttgcattc gtaggtacat tgattttagg atttgacgaa caaacacaag
    20101 acaatcaatt agaaaacaaa catgcgaatg caggagaacc gattacttca gcacggcata
    20161 ccttaaaaag tcctttaacg ggtaaagtac tgccattgag tgaagtacca gaccaagttt
    20221 tttcttctgg cgtgatggga aaaggtatcg ctattgatcc agaagtagga gaactagttg
    20281 cacctgcaga cggagagatc acgactattt ttccaactgg acatgctgta gggatcacaa
    20341 cgactgacgg agcggagatt ttgattcata tcgggatgga tacagtagaa ttaaatggga
    20401 atggctttga gatcttagtc aaacaagggg atctcgtcaa agcaggagat ttattgattc
    20461 gttttgacat cgaagcaatt agagcagctg gctatagcgt aatcactcca gttgtcatta
    20521 cgaatactga tgcatttgcc gatatacttg aattagacca aaaagagatt attgcaaacg
    20581 aagatgttct ggcaattgta aaataaggag gaaatcagga tgcaatcacg tttttcagaa
    20641 aaatttttat ggggtggagc aactgctgcc aaatcaatta gaaggggctt atgatcgaga
    20701 cggaaaagga ctatccgttg cagatgctat gcctggaggt aagcagcgct ttgcgattat
    20761 cggcagtgaa gaatttgact ggacgattga tcaagaaaaa tatatttacc cgaatcatcg
    20821 aggaatcgat cattacgatc gtttcaaaga agatcttgcc ttgtttgcgg aaatgggatt
    20881 caaatgttat cgtttttcga ttgcctggac acgaattttt ccaaatggag acgaaggtac
    20941 tcctaacgaa gcgggattag aattttatga tcagctgatt gatgagtgct taaaatatga
    21001 tattgaacct gtgatcacga tttctcatta cgaaatgcct cttcatttgg caaaagaata
    21061 cggtggctgg aaaaatcgaa aactgatcga cttctatgaa cgatttgctc agacagtatt
    21121 agagagatac agcagtaaag tcaaatattg gatgactttc aatgaaatca attcggcctt
    21181 tcactttcca gctttaagtc aaggattagt aaaaagcaat ggagcaggag agtaccaaaa
    21241 tattttccaa gcatggcata atcaattcgt tgcaagtagc aaagccgtaa aaatcggcca
    21301 cgaattgcgt tcggatatcc aaatcggctg catgattatc tatgcaacaa cttacagcat
    21361 cgatgccaat ccagtcaatc aggcagcaac aatgatccaa aaccaagaat tcaatttttt
    21421 ctgcacggat gtccaagtac gtggagaata ccctgcatac acagcgcgta cccataaaaa
    21481 atatggagtc gatccggaaa aattagagca aacggaaaaa gacttccagt tgctaaaaga
    21541 atatccagtg gactacatcg gatttagtta ttatatgtct acggcaatca atgagactga
    21601 tccacaagca gcaacttcag aagggaactt gctgggagga gtaaaaaatc cgtttcttga
    21661 ggcaagtgaa tggggctggc agatcgatcc agaagggctg agaatcgcat tgaatgaatt
    21721 atacaatcgt taccagaaac cattattcat tgttgaaaac ggtcttggag ccattgatca
    21781 tatggaagag gatggcacga ttattgatga ttatcggatc gattatttac gtcgtcatat
    21841 cgaagcgatg gctaatgcag tagcagacgg tgtagatttg atgggctata cgccttgggg
    21901 atgtatcgat cttgtcagtg catcaacagg agaaatgagt aaacgttacg gctttatcta
    21961 tgtggatcta gacgatgaag gaaatgggac actgaatcga tcaaagaaaa aatcttttga
    22021 ttggtataaa gaagtaattg cctcaaatgg cgtaaacttg taattaaagc agctgaatga
    22081 aaaagaacac acttctcaca tgtgatttgt gttctttttt tattttttat gtgctattct
    22141 tttagtaata gtaaagcaaa gggtgacgtt atgaaaagga cacgtgtact atacttggaa
    22201 gtcgcagata aaattaaaga agatattttc tcaggaaaat atccagtcgg ttcgatgttg
    22261 ccgacagaaa gtgaattaga agaactgttt caagtcagca aaatcactgt ccgaaaggca
    22321 atcgaactgc tggcatcaga tgaatatgtc gcaaagaaaa gtggtcgtgg gacgacggtt
    22381 ctaagcaatc gtccttacaa tcgattatcc aaagcggcaa gctttacgca aatcttggag
    22441 aactcccgat atgaagtccg gaaagaaacg ctggatttgc aattggtcca tataaagaag
    22501 gaagatcctt tgttttcctt tttcggtgag caagctgttt gttttaagcg cttatattat
    22561 ttgaacaatc agccttatat ttattttgtt cattatcttc cacaagaaat gatgcaattc
    22621 agcagagaag aatttggcaa agaatctttg tatcgtttgc tgacgaaaaa aggatatact
    22681 attgactcat tttctgatga tttctcggca gtatttttaa cagaagaaga acaaggaatt
    22741 ctgaaaacag acgcacagat cggcatcaaa cggatacgga aatcgtctac gcaaattggg
    22801 gaaatgattg aatattcgga ggcggtctac catacggagc tgcatcctta ccatattgat
    22861 tatgaaacat aaataaaaaa agaggttgtg aaaaagctgc cctgcatcaa gtaataagaa
    22921 cagccaaaca aaaatagctt ctcatatttt tcgtttggtt aggcttatta ccgcagatac
    22981 acggctgttt ctggattacc atttattctg gataaggggg tgtggcacga ttttcagaag
    23041 gaatctatga accaatcact gtattgattt tagcttcgat ggtaacccca ttcggcttga
    23101 cgatcgctta tttcttaggg aaaatcattc gtaaaaatat actcaatcgt caagaaatcg
    23161 atacattgaa gaccgctttt cctatgggga tctgtcagat cacagaggga tgtttcccta
    23221 tcgtattgaa cgacttggca cgcaatgtca tagcaacggg agtcggtggg acagtaggtg
    23281 gcggattaag catgttttgg ggcgcagata gccgtattcc ggcatcggga atgtttgcag
    23341 tcgctacgat gaccagacca tgggcattca ttggtgcatt gttagctggt tcttttgtca
    23401 caggaataac cattttatta ttgaaaaaac cagtagatcc gaatgcagaa atcatccaag
    23461 aagaaaaaga ggaagaagac atatcttggg atgatttgac aattagttag gagaggcaga
    23521 atggattaca agaaaaaagt acaatagatg taccttgaga caggaatggt atgaaagaat
    23581 cagagttaga aagaatcgaa tatacagatt ttggtttagg agcgatcgaa actgtccaga
    23641 gcatcggcac cctccttgaa atgacgatga aggaaaaatg agaacctttc gttgtcgaaa
    23701 gggtctggta taccttatgt cgaaggaaag gaaacaaaaa aactttcctg tactattcca
    23761 aaaaggaaag aaagttatta tacagtaaaa aaagaaatta ttcttcatgc tagagatcag
    23821 tacacgttcg agcccaatat caaacactag ttccaggcag gcgcaacagg tgcggttatc
    23881 actgaatttt cttccagcag tgacgattca agtgatattt ttacaaatcc agctatttat
    23941 cgttaacaaa aagattttta ggagaagctg atgaacaaaa atgatcaaat tttgatcgtt
    24001 tagttcgtcg gcttttttat ttagagaaac atcatttatc agtgaaacat aacacgagaa
    24061 caaaatgatt ttttcgttaa taaaagaaac aagtatttgt tgtttaaaat aatacacgtt
    24121 attggcatat aggacgaaat cccagtatct tctataagta agtcatttca tatcgatgaa
    24181 aacacgttat ttatttttgt tttatctata aaatggctga aaaatgattt ttttctaaat
    24241 actatatata gtggcgtcta tcctatatac cactaaaaaa ctacaaaatc tagtctttta
    24301 ttttaaaaaa acacgtgtag aatgaagata gacttttgag ttagggagtg tttttttatg
    24361 aaacttactg ttttttgcgg ttcccgtttt ggtaataaag aaagttacaa atttattgcg
    24421 caaacgttag gaaaatacat ggcacaagaa gaaatcgaac tggtttacgg tggttcatac
    24481 tccgggatta tgggagtgat tagtaaaaca gtactggaaa ataacggaaa agtcacaggt
    24541 atctatccga atgggctttt tgaaactgaa ttgcctggaa aagatgttac tacatttatt
    24601 cctacagaaa cgatcgatga aagaaaggta ttattatttg aaaagggaga tgctgtcctc
    24661 gttttccctg gaggtctagg tacattggag gaattctcac aacttctttc ttggatagca
    24721 atcggtctga cgcccgacaa gccaatcgga atattgaata ttggcggtta ttacagcggc
    24781 ttgcaacaat tattagaaac ttttgcaaaa gaggatttta tggataaaaa atggttggat
    24841 caagtaatct tttccaacaa tccattggaa ctggtcaatg aattacgagc agtatctatt
    24901 aaaaatcagt tattattgaa ggaggcaaaa taatgagtca aatatattta gcaggaccat
    24961 ttttttcaga ggagcaaatc gatcgagtaa gtcgtatcga aaaagcgttg gaggaaaaca
    25021 aaacagtcac aagtttctac tctccacgtc atcaccaaga aagcaattat gaactattca
    25081 gcgctggatg ggcgcaggaa gtatacgaaa aagatatgga agaactgaca aatgcagaat
    25141 ttgttgttgc tatccttgac tttgagcatc aaacaatcga tccaggaacg gcttacgaat
    25201 taggtgtggc aactatgttg aaaaaaccga tgatcattgt acaagaagag acggtaccta
    25261 cgaacttgat gattacacaa agtctccata cgtatttaaa atcagaccaa gctgtacgtg
    25321 aatatgattt tgaaacattg cctgttgaaa cttacgtagg cgagtactta tagaagagga
    25381 agggttgtat gtcagtgatt ttgatttcag gaacgattgg tgcaggtaag agcagtttga
    25441 cggatatgct tgcaaaagag attgattcta aaccatttta tgaaaatgtc gaagataacg
    25501 aagtattgcc gctcttttat tcaaatcctg agcagtacgc ttttttattg caaatcttct
    25561 ttttgaacaa gcgattttta gcaatgaaaa atgctttagt gaacgatgac aatgtgctag
    25621 accgatccat ctatgaagat agcctgttgt tccatctaaa cgctgattta ggtcgggtaa
    25681 cggatatcga agtacagcag tacgatagct tattagatac gatgctaaac gagttagatg
    25741 atgttgctcc aaaaaaacgg cctgatttga tggtccatat caaagtttct ttggacacga
    25801 tgctagaacg tatcaaaaaa cgtgggcgtg actatgaaca gctagaaagc gatgagacgt
    25861 tatataccta ttatgaaacg ttgaacaccc gctataatca atggtatgaa gattttgatg
    25921 tatgtcctaa aatacaagtg gatggggata aattcgattt tgtagaaaat ccagaagatg
    25981 caaaaaaggt gatccgtcag atccaagaaa aattagctga attggaagga aagcctgctg
    26041 gaaaatattt tacggataac cagcatgcaa aaggtcaaga attaggctaa aaataaaaaa
    26101 ccaaacgacg ggaaagaaaa attactacgt gatgtagaat aagcctttct atcgtttggt
    26161 tattttatat tcaaatattt gaaataaata aatctttact ctttgatttg taaactgaaa
    26221 tgatccactg tttgttttac tgatgaagct tgatcaaagg aagaagctga gtttgaagtt
    26281 cataaaaatc agccatagtg agttttgctt ggatttgttt atcttcttct actttttaca
    26341 taattttgaa caggataaga ttcaaatgtt ttaaatgaat ctttgactag tttgtgacag
    26401 ttgtcgcata tgctcaagct tccttggtca ttaaattctg tatggatatt tttgttgtta
    26461 ttacatgtac aataatcagg actatcgatc atccatttcg tctcctttac aatcatcttg
    26521 cttctttact atagcagaaa agaaggggag aaacaaaaga agatccaaca gacggcacta
    26581 tagactgtag atgttgccat cctcatcctt caaacggtaa ttaccgattt ttgtaaatat
    26641 gactgttgtt tcttttttat tttcttttcc tgaaataata tattcgtcat ctttggtagt
    26701 gatcttgata tctgtcagca ctgttttttc ttcagatgat tcagaagaat cagttccttg
    26761 tgtctgatac gtgcgtgtcc attccatttt tttatctgta aatgtcaact gtcccgcgga
    26821 taaatccata tctttacgta cttttagcgt atatacactg ttggtggtat ctgctttttc
    26881 cgcttttaag acagaagaat cggttgtttc gtccgaggat tggtcagagc cgccaaacaa
    26941 atcacagcca gtcaatgtca aaagtcccgc agacaaaata aatagtacga ttaatttctt
    27001 caaaatactt cccccatttg ataggataaa gaaattatac cattggaatg taaaacttca
    27061 aacggatgga agagaaaaac gcacaaaaca cccacaaata gagtaaattt tagaataaaa
    27121 ttttaaaaag gcaaaaaatc cgccactttc agaaagcgtt ttaaaaaagt gttgcaatct
    27181 tttaaaaaaa tgctatatta aaaatgaacc ggttcaaata cttgtttaag tataattaat
    27241 agtgagagga agttgctcta ctgaagactt tagttatatg gatattgatg acaagcaaca
    27301 ctatgcaaag aatgcggtca tcataatcga acaacaagaa agagaaatca aatgtaactg
    27361 gcaggagtga gaatgtatgg catcgatccg tgatgtggct aagatggctg gtgtttcagt
    27421 gggaacagtt tcccgttact tgaatggtca gcaactgaag gaaaagaaca tgaaaaaaat
    27481 agcagaagcg atttcagcgt tggactataa agaaaacatc attgctaaag ggttgaagaa
    27541 taatcgaagc ttctctattg gacttttgat aaacgggatt tccagccgtt ttgggtcgga
    27601 agttgtctca gggatcgaaa gagtagctga agaaaatggg tatagcttat tattaagcgg
    27661 gtttgccgat cagccagaaa aaattgaaca aaaaattgaa tacctgatga agcatgtgat
    27721 cgatgggctg attgtcttct tatccgaaga agagtggtct ggatttgaaa tgctcacaaa
    27781 aatgagtatt ccagttatcg cattgaattg tccagaagga ccagcaggta ttgatacaat
    27841 attagtgaat gatcgagaaa gtgtagcaaa agtgatcgct catcatggtg aacaaggaca
    27901 taaaaaaatc ggatttattg ctgccactca aacagactac gtagcaagag aacgtttagc
    27961 aggagccaaa gaagcggtcc aaaatgatcc atcgatccaa ttagaggtct ttacaggaga
    28021 ctattctaga aaaagcggct attacggggc aaaagcatta ttagaaaaag gggcaactgc
    28081 tatttttgtc agcaattaca atatgtcgat tggtgccatc gaatgtttca atcaagaagg
    28141 tgtcagaatc gggaaggata ttgcgttcag tcactatgat tatttagata aaaacgatct
    28201 gagtatcctt ccgaaaatca cgatcacgcc accaacagat aaaatcgggg aacgagcagc
    28261 agaacagctg ttaaaacgaa tcaaaaaaga agaggaagaa aatgaaaaag tgattgtgat
    28321 ggaaaatatc atacatggaa tcaactaaaa cgaactaaaa aagaaaaaga ggtgctttga
    28381 tgaaaaaata tcaatttcca gcaaattttt ggtggggttc tgcagcaagt ggcccacaaa
    28441 cagaaggaag gatttcaggc gatggaaaag gagagaacat ttttgattat tggtacaaaa
    28501 aagaaccgca aaagttcttt gatcaagtag gacctgaaaa aacctcgcaa gtttatacga
    28561 agtatcaaga ggatgtacag ttgatgaaac agactgggca taattcattt cgaacatcta
    28621 tccaatggag ccgtttgata cctgatgaat ctggaacaat caacgaagaa gccgttcgtt
    28681 tctatcatcg ttattttgat gagttgattg aaaacggtat cgaacccttt gtgaatctgt
    28741 atcatttcga tatgccgatg tatctgcaag aaaaaggcgg atggttgaac cgagaaacgg
    28801 ttgaagccta tgaaaaatat gccaaaagtt gttttgaatt gtttggttcg aaagtaaaaa
    28861 aatggtttac tcataatgaa ccaatcgttc cagtcgaagc aggttattta tatcgatggc
    28921 attatccaga agagtcagat atgaaaaaag cgatccaagt tggctatcat gaagcgttgg
    28981 cttcagcgtt agccatcaaa tcttaccatg aaatggagca aggtggtgtt attggtatca
    29041 tcttgaatct gacaccaagc tatccaagag acgaatcaaa ccctgaagat gttaaagcag
    29101 cgcaaatagc agatgcgttc ttcaatcgtt cattccttga tccagctgta aaaggcgagt
    29161 ttccaagtga attgattgag atagtaaaag aacttgatct catgcctgtg atccatgcag
    29221 aggatttgac ggttatcaaa gaaaatacag tagatctttt aggtatcaat tattaccagc
    29281 cacgccgggt aaaagcaaaa gaaacaccaa tcgatactaa aaacggtcca atgcctgagg
    29341 attatttcga caattatgaa atgcctggtc gtaaaatgaa tccttatcgc ggatgggaga
    29401 tctatgaaca aggaatctat gatattttga tcaatgtacg agatcattat ggaaatatcg
    29461 actgctttat ttctgaaaac ggtatgggtg tagaaaacga agcacgattt atcaaagaag
    29521 atggcatgat ccacgatgat tatcggatcg aatttgtcca atctcatctg aaatatgtcc
    29581 atcaagccat tcaagaaggt gccaattgtt taggctatca tatgtggaca tgtatggata
    29641 actggtcgtg gaccaatgca tataagaatc gatatggctt tatttcagta gacttagcac
    29701 aagatggaaa aagaacaatc aaaaaatcgg gtcattggtt caaagacgta tcagataaaa
    29761 acggatttga ggcttaagaa agaatagttg agagcaaatg cgtgaaattc tccattctta
    29821 ccattttgtg aaaaagaagt tcaattattt acgatctttt tcaacttttt tgtctttcta
    29881 tttcattttt tgtatataat agaatagtca aaattaaata ggagtggagg aaagcatgag
    29941 gaaaaaaaga ccgtttcttc tcttttggtt attcggtttt ttcttactgc ttattttatc
    30001 cgcagcattt tcaggaaaaa tgacagcaga tcttgctcag aaagaaacag aaaaaatcgt
    30061 agcaagcaaa gaatcagtag ataatttcaa aaaagaattc tcaacttatt ggtgggcgga
    30121 gtataaaata actgccaatt acgaaaaagg cgaattggac atttatttgc caaaaggaaa
    30181 agaagaaaat caatttatta atatcgatga cgtacttagt gcgatttctc tcagacaata
    30241 tcaatttaaa gacaagcatt tgaccgtttt gcttttgact catgatggcg acaaagtagc
    30301 ccgtttgaaa aatggaaaag tgatcaccgc ttattctgaa aaagtagaca aaaaagtggt
    30361 cgccgatcgt ttagcggaat ggaaaaagac aaatgaacaa gtcaagaaaa caactgtctc
    30421 ttctcaaaaa aacgagtcga caggaacaag tccttcagat tctggcagtg gacaaacgat
    30481 aacgggaagt gaagaaaatc aagcctcaat tattacgaat gagtcatcac aaggacaata
    30541 tcaatcctat ggacaatgaa aaa
//
LOCUS       DAFENC010000032        29098 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.032, whole genome shotgun sequence.
ACCESSION   DAFENC010000032
VERSION     DAFENC010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29098)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29098)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29098
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.032"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..1030)
                     /locus_tag="LP493_001848"
     CDS             complement(<1..1030)
                     /locus_tag="LP493_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2133996.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1112..1801)
                     /locus_tag="LP493_001849"
     CDS             complement(1112..1801)
                     /locus_tag="LP493_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBL2133997.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="LP493_001850"
     CDS             complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="LP493_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HBL2133998.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2328..2831)
                     /locus_tag="LP493_001851"
     CDS             complement(2328..2831)
                     /locus_tag="LP493_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HBL2133999.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3035..3162)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="LP493_001852"
     CDS             complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="LP493_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HBL2134000.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="LP493_001853"
     CDS             complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="LP493_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HBL2134001.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4799..5467
                     /gene="sdaAB"
                     /locus_tag="LP493_001854"
     CDS             4799..5467
                     /gene="sdaAB"
                     /locus_tag="LP493_001854"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HBL2134002.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5480..6352
                     /gene="sdaAA"
                     /locus_tag="LP493_001855"
     CDS             5480..6352
                     /gene="sdaAA"
                     /locus_tag="LP493_001855"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HBL2134003.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6443..7462)
                     /locus_tag="LP493_001856"
     CDS             complement(6443..7462)
                     /locus_tag="LP493_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBL2134004.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7635..8540)
                     /locus_tag="LP493_001857"
     CDS             complement(7635..8540)
                     /locus_tag="LP493_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBL2134005.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="LP493_001858"
     CDS             complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="LP493_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HBL2134006.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9245..9415)
                     /gene="secE"
                     /locus_tag="LP493_001859"
     CDS             complement(9245..9415)
                     /gene="secE"
                     /locus_tag="LP493_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HBL2134007.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="LP493_001860"
     CDS             complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="LP493_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBL2134008.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9753..10397
                     /locus_tag="LP493_001861"
     CDS             9753..10397
                     /locus_tag="LP493_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBL2134009.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10453..10956)
                     /locus_tag="LP493_001862"
     CDS             complement(10453..10956)
                     /locus_tag="LP493_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBL2134010.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10969..11015)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11553..12518
                     /locus_tag="LP493_001863"
     CDS             11553..12518
                     /locus_tag="LP493_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBL2134011.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12617..13789)
                     /locus_tag="LP493_001864"
     CDS             complement(12617..13789)
                     /locus_tag="LP493_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2134012.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13776..14921)
                     /locus_tag="LP493_001865"
     CDS             complement(13776..14921)
                     /locus_tag="LP493_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2134013.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14935..15867)
                     /locus_tag="LP493_001866"
     CDS             complement(14935..15867)
                     /locus_tag="LP493_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2134014.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15984..17063
                     /locus_tag="LP493_001867"
     CDS             15984..17063
                     /locus_tag="LP493_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBL2134015.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17060..17678
                     /locus_tag="LP493_001868"
                     /pseudo
     CDS             17060..17678
                     /locus_tag="LP493_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
     gene            complement(17788..18015)
                     /locus_tag="LP493_001869"
     CDS             complement(17788..18015)
                     /locus_tag="LP493_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL2134016.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18118..20706)
                     /locus_tag="LP493_001870"
     CDS             complement(18118..20706)
                     /locus_tag="LP493_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HBL2134017.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20726..21385)
                     /locus_tag="LP493_001871"
     CDS             complement(20726..21385)
                     /locus_tag="LP493_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBL2134018.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21434..21937)
                     /gene="trmL"
                     /locus_tag="LP493_001872"
     CDS             complement(21434..21937)
                     /gene="trmL"
                     /locus_tag="LP493_001872"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HBL2134019.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22158..23024)
                     /locus_tag="LP493_001873"
     CDS             complement(22158..23024)
                     /locus_tag="LP493_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBL2134020.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23133..23774
                     /locus_tag="LP493_001874"
     CDS             23133..23774
                     /locus_tag="LP493_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HBL2134021.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23836..25197)
                     /gene="mgtE"
                     /locus_tag="LP493_001875"
     CDS             complement(23836..25197)
                     /gene="mgtE"
                     /locus_tag="LP493_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HBL2134022.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25215..26114)
                     /locus_tag="LP493_001876"
     CDS             complement(25215..26114)
                     /locus_tag="LP493_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBL2134023.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26116..26913)
                     /locus_tag="LP493_001877"
     CDS             complement(26116..26913)
                     /locus_tag="LP493_001877"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HBL2134024.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26891..27595)
                     /locus_tag="LP493_001878"
     CDS             complement(26891..27595)
                     /locus_tag="LP493_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HBL2134025.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27726..28301
                     /locus_tag="LP493_001879"
     CDS             27726..28301
                     /locus_tag="LP493_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HBL2134026.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28419..29096
                     /locus_tag="LP493_001880"
     CDS             28419..29096
                     /locus_tag="LP493_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBL2134027.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8562 a         6167 c         5231 g         9138 t
ORIGIN      
        1 atacagtatt atttcggttg cttgctgctt cacctagccc ttgtactcgt gtttgattgg
       61 cgacttgacc aaattgattc ccgacgtcta ataaaataat agctaaaagc aaaatggcca
      121 aatggcttcc gccaaccaat aaagcaataa agcttattgt ttgcataaca agtcccatat
      181 acacgatttt tctttcagaa taagaatctg ccagtcgtcc cacgataggt gcagcaactg
      241 ctccagacaa accaaaaatc gctaatatcc ctgcttcgaa tgttccccaa ttgtaggcgg
      301 gactgctgat ataaaaaatc aacgtagacc aaaagatcga aaatgttcca aacatgaaaa
      361 atccactgac tgccgcttct cttaatagac gttgagaagc aactaaatgc ggcaaacttt
      421 taagtgaatc aaggtatgaa acagctgtac tactttgctg gacagaacgc ggcattttcc
      481 agtaaagcag aagtgtaaga attccgactg cacataaagc aaataaatag atcatccgcc
      541 aagaaaaaag actggcaaca ataccagata ccgtccgaga aagcaaaatc cccacgagta
      601 aaccgctaag caatgtaccc atgaccttcc ctcttgcttt tggtcccgct agtaccgcac
      661 cgtaaggaat gatgatttgc ggcacgatcg aaagtaatcc tattaaaaaa gaagcgcatg
      721 caaataacgt aaacgaaggc gcaaaaaaag cggccaacag agagacggca gataacgcta
      781 ccattcgaat gatcaatttt ggacgatcca ccacgtcccc taaaggaact aaaaacagta
      841 accctaacgc atagcctaat tgggtcaaca tcgtcaatat cccgactgca cttgtgctaa
      901 cagataaact agctgctact tttgttccaa tcggctggat gtaatacata ttggcaacaa
      961 caacgccaca agtgattgat aatagtaaaa taagcgaagt tgttaaaggt gttttttcat
     1021 tactcttcat tgatttcccc catttcctat cttagtttac aacttatgga aaagattgga
     1081 aatagaaaaa tacaactatt cgccacactt attatttgtg cttttgtttt ccttgttttt
     1141 tcttgcgatc tttataaatg aagacaacta accctactag cacagtaaca cttgcaacca
     1201 acgtgactgc agttttgtta tatccgtgaa acagagcttc tccaccacac gcatacaaca
     1261 cagacgaagg gatgactcca atcacgatcg acaatatgat ttgctgtaga ggcaatttca
     1321 tcgcatctgc agcaaaattg accatagaag atggaataac cggtatcata tagcctaaca
     1381 ttacacctat ttttggatgt ttcatttgtc ggattgcttg cacccaatga ttcgtttcgg
     1441 ttttcttatc taaaaatttt aagcgatgca taaggaaaat tgcagtgatg ttaccaagag
     1501 cattacccaa aatgttgatg atcgcacctg tcagtggtcc aaagctcaaa ccagcaatga
     1561 ctccaactac tgaagtagga atacctggaa cagcacacat caccgctgtc aatacgatca
     1621 agagtatcga tgcaaaagtc ccatgcgaac gaatatgtgc gagtagctct gccttactcg
     1681 ctctcggatt taaaaataat tggatgtctg tctgatattc taaatacaac cgatagccca
     1741 ctaccagtat cagaatgatt cccaacgaga tcaacatcaa tcggattatt ttctttttca
     1801 tatttcctcc tgaaaaaaat ctatattcat taaataatag tttaacataa aaacaaaaaa
     1861 gcaccgaaat ccaacatagg atctcagtgc ttttaaatag taaaaattat ttaacagtta
     1921 cagatgcgcc aacttcttca agtttagctt tcaattcttc agcttcttct ttagatacgc
     1981 cttctttaac tggtgcagga gcgccatcaa ctacagcttt agcttctttc aagcctaaac
     2041 cagttgcttc acgaactgct ttgataactt taactttttg gtctccagct gcagttaatt
     2101 ctacagtgaa ttctgtttgt tcttcagcag cagcagcgcc accagcagca gctacagcta
     2161 caggagcagc agcagatacg ccaaattctt cttcaatagc tttaactagg tcgttaagtt
     2221 ctaggatagt tgcttctttt aactcagcaa cgatgttttc aatgttcaat gccattataa
     2281 tttcctccgt ttaattgttc ttttttattt aatgctttat gcggcaatta agctgcatct
     2341 ccatcttctt tgtctgccac tgctttgaca gcgtaagcca cgttgcggac tggcgcttgt
     2401 agtacagata gcaacataga tagaagtcct tcgcgatttg gcaattttgc caatgctgtg
     2461 atttcttcca atgaagagac tttaccttcg atgataccgc ctttgatttc taatgctttt
     2521 gcttctttag caaattcgtc catgattttc gctggtgcga ctacatcttc gttactgaat
     2581 gcaacagctg taggtccagt gaatacttcg tccatgcctt caaggccagc ttttttagct
     2641 gcacgtgaaa gaatagaatt tttgataact ttcatttcta cgttagcatc acgaagttgt
     2701 ttacgtaaac gtgttacttc atcaactgtt aatccgcggt agtcaacgac tactactgat
     2761 gcagctgctg taaatttttc gcttacttca tcaacgattg ctgctttttt tgcgataatt
     2821 gcttcactca tttttgagtt tcacctcctg aattttgatg gaagagtttt ttgcactgaa
     2881 aaggcaagtc acttttatag ttactttgct caaccagtat tattcatcac ctattcactt
     2941 cgttcatagt gattctactc gctttgctcg aaaggaaact cctttcgctt tgctcaacca
     3001 gtattgttca tcatctcttc acttcgttca tagtgattca caataaaaaa ctctatgcca
     3061 ccgcagacat agagggacta ttgaatatat tcaataaacg tcctcggtag gaaattaagg
     3121 cttgatgcca cctactgtct tcggtacaag ttaattatta acctcaacta gcttagcatg
     3181 ctaaactagt tgagtcaaga attatttttc agttggatca atcaacattc taatatttaa
     3241 ttagaaagaa gcttggtcaa catggatacc aggtccaaat gttgttgtga tcgttacatt
     3301 tttcatgtat tgacctttag ctgctgatgg tttagctttt agcaatacat catggattgc
     3361 tgcaaagttt tcaactaatt tttcatcgtc aaatgaaact tttccgattg gtacatggat
     3421 atttccagct ttgtccacac ggtaagttac tttaccagct ttcacttcgt ttactgcttt
     3481 tgttacgtcc attgtaactg taccagtttt agggtttggc attaagcctt ttggtcctaa
     3541 tactcgtcct agacgaccta cagtagccat catatcaggt gttgcaacaa ctacatcaaa
     3601 gtcaaaccat ccgttttgga ttttttgaac catgtcgtcg tcacctacga aatctgcacc
     3661 agctgcttca gcttcttttg ctttgtctcc tttagcaaaa actaaaacag tttgtgtttt
     3721 accagttccg tttggtaata caacagcacc acggatttgt tggtctgctt ttttagggtc
     3781 tacgttcaaa cggtatgcaa cttcaactgt tgcatcaaat tttgcaatgt ttgtttcttt
     3841 tgctaaagct actgcttcgg caacaggata aactttactt gaatcaactt tttttaatgc
     3901 atcttgcatt tttttgctct ttttagccat tttggttcct ccttgattgt ggttataacg
     3961 gttgtacctc ccacgtgttc tatatctttc aatatagagc caactgagaa gctgctgtct
     4021 tagggtgtat agattattct acagtgatcc ccatgcttcg tgcagttcct tcaaccatgc
     4081 gcattgctgc ttcaacgtta gctgcgttta ggtcttccat ttttaattca gcgatttctc
     4141 ttacttgatc gctagaaact ttcgcaactt tatttttgtt tggttcgcct gaaccttttt
     4201 cgattttagc tgcttttttc aatagaacag cagctggcgg tgtttttgta acgaatgtga
     4261 atgaacggtc ttcgtataca gaaataacaa ccggaatgat caaacctgct tgatcagctg
     4321 tacgagcgtt gaattctttt gtgaatccca tgatattgat acccgcttga cctagtgcag
     4381 gacctactgg tggagctgga gttgctttac ctgcaggaat ttgcaattta acgatttttt
     4441 ctactttctt tgccacgaga catacctcct taagtccgtg atgtggttaa ttggagatgc
     4501 atatttctcc tcccacgttt tatctgatct gaaaaaatcc agacaaataa tgtgcaaaac
     4561 aatgcacact ggtacagtat agcaaattta tttgtttttt caagattttt ttctgctatt
     4621 tttacatttt gcttgaataa acgctaaatt tattctaaaa aaacaacaat ttttcgttct
     4681 catttcttct tttatgttac acttgcgcta gcatggttca acagatgaaa gcaaacaata
     4741 acacggtttt ttagaccctt gtacaaagat tcctacataa caaaatgagg tggagaaaat
     4801 gaaagattta aggtatagaa gtgtctttga tattattgga cctgtgatga ttggtccaag
     4861 tagctctcac actgccggag ctgctagaat cgggaaaatc atacgtagta tatttggcga
     4921 acagcctgat tctgtagata tttatctata tgaatcattt gcaaaaacct atcgggggca
     4981 cggaacagat attgcattag ttggcggcct gttagggatg gaacccgatg atgaacgttt
     5041 agctgattct ttgaaattgg catatgaagc cggtatggaa gtcttgtttg ttcctaagag
     5101 tgaaaaagcc gaacatccaa actctgtaaa gatgcttcta aaaaaaggaa cacgaaagct
     5161 ttcagtcact ggcatttcga tcggcggtgg caatatccag atttctgaat tgaatggatt
     5221 caaaatttct ttaagcatgg gtactcctac cttgatcgtt gtccaccaag atgttccagg
     5281 tatgattgct aaagtgacta gtatactttc tgagaccaat acgaatatcg gcactatgac
     5341 agtgacacgg gaatcaaaag gtgaaaatgc cattatgata attgaagtag atgatcctca
     5401 agtagaagaa acggtaaaaa gactcaaaca gctgccaaat atcgacagcg taaattattt
     5461 cgattaagga gctaaaaaaa tgtttttatc gattgaagaa ttagtagatc aagcaaaagc
     5521 ttatccaagt gtagcagaat tgatgattgc agttgaaatg gaaatgagtg gccgttcccg
     5581 tagtcacatc atcgagatca tggaaaaaaa cctctcagta atggaacaat caatcaacga
     5641 gggaaaagaa ggtgttacct ccgtcacagg aattaccggt ggtgatgcaa aaaaattaga
     5701 tgattattta aatgaggcag actttttaag tggagaaaca atcttaaaag ctgtacgcaa
     5761 tgctgtagct gttaatgaag tcaatgcaaa aatggggttg atttgtgcta caccgactgc
     5821 cggaagcgcg ggtgttgttc ctggtgtgct gatggctgtc cgagatcggc ttgatttgac
     5881 acatgaacag caattggaat tcttatttac cgctggcgct ttcgggttag tcatcgcaaa
     5941 caacgcttct atcagtggtg cagaaggggg atgtcaagca gaagttggtt ctgcaagtgc
     6001 aatggcagca gcagctttgg tttgtgcaaa aaatgggact cctcatcaag cagcacaagc
     6061 agtagccatt acattgaaaa atatgatggg actgatttgc gatcccgttg caggcttagt
     6121 tgaagtcccg tgtgtcaaac gtaatgcttt aggctcttct caagctttta tctctgctga
     6181 tatggcatta gcgggtatcg aaagtgtcat tccgccggat gaagtcgttg ctgcaatgta
     6241 ccaagtcgga cgtcaaatgc cgtcgatttt caaagaaaca gcagaaggtg gcttagctgt
     6301 tacgccaact gctaaacgac ttgcggaaga gattttaaat aagagggcgt gataaagctc
     6361 cttaatttcg agtattaaga gattagttat cttcataaca aaaaacgaag agaggactaa
     6421 ttgcccttct cttcgttttt tattaatcca tcaatttcgt attttttact tcatcgatcg
     6481 tttttgttcc tgcaagttgc atcgtgatcg acaattcttt gttcaggtgt tcaaaaacag
     6541 atgttactcc ttctgcccca cctagattca acccataaat cactggtcgg ccaatcgcaa
     6601 ctaagtcagc accacttgcc agagctttga agacatgctc tcctcgacgg acaccagagt
     6661 cgaaaatcac tggtacacgt ttgttgacta cttcggcaat ttttggcaat acttcaaagg
     6721 acgcaggacc tccatctaat tgacgtccac catgattgga tacccagata ccatctgccc
     6781 ctgcagagat agcgattact gcatcttctg gcgattgtat tccttttacg ataactggaa
     6841 gatgggtgat ttctttgatt gttttgatgt catctggtgt caagccttgt tttgcagctg
     6901 cataaatttc tgcgattcct tttccttcgc cattaccact tgcactttgt tcgctatacg
     6961 cagctaagtt aggcattggt aatggaaatt ggaattgatt gatgacgtct tcttcacggt
     7021 aaccaccgag cgttgaatct gccgttaaaa tgatagcttt agcccctgct tctactgctt
     7081 tgttcaaaat gaactcattg aatctgtcgt ctttactcat atataattgg aaaaactgcg
     7141 gtgcgcctgg cgctgcatcg gctgcgtctt tgattgtcgt atttgcataa gtgctgatgg
     7201 aaaagattga tccagcagca gctactcctt tagctgtatc agcttcccct ttttcatgtg
     7261 ccaatccttg ggccgctgat ggcgcttgga taatcggtgt atctaattca attccgaaaa
     7321 cagatgtatg caaatcggct gagtcgattc cgcgtaatat ccgtggcatg attttctttg
     7381 tattaaaaga agtcgtattt tctttcatcg tccactcatc ttcagaacca ccgcgaatat
     7441 agccaaaagc tcctgcttcc atgcgctctt ttacacgacc ttctagttag gcaatgttta
     7501 caatatcgat tggatgttct tcattacttg tatgataagt catagtagat ccttctttca
     7561 tcttcttgat tacatataaa tcatactaaa cttacaaaaa gtaagcaaac atttactctc
     7621 agatactttt atcgctattc tttccaaata aatcgactta caagctgatc tacttcttgg
     7681 ttttcatgaa gcatactatg agaggcattt tcacctgtca ctactttttc ctctatttca
     7741 tttccgcgtt gcttcaacaa cgcatagacc gctaatgcac tgtttaacgg tactgttcca
     7801 tcactcaagt ctgtttcatc tagttgacca gcaatcaaga aaaatcgagt ggttatagga
     7861 atattaccga tcatttgctg gtaatcttga tagcggttag aaacgacagc aggccccttt
     7921 gctaactcat ctgtcagaga ctgcgcacta tcatcgacaa aatcattaaa aggcgcgcca
     7981 attgctgtta atgtctgaac ttgtggcaat gacgtatcct gtccatacgt tcctaaatag
     8041 cgtagtgcac taactcctcc catggaatgc cccactatgt tgactttatc tatgccgtag
     8101 ttttctttca gatacaaaag acaagttttg atccattctg cttgattcca ctcgttattt
     8161 ttattatctt caaacaatac ttggaccatc ggattgtctg cttttccaga caaatctcct
     8221 gttgcttgta tttgtccatc tgttcctact gttaaaacca attcttttac tgcttgctga
     8281 tttttttcca aacgccgcaa catcccttta aaggaatttt ctgtcccgct gtagccgtgg
     8341 aaaaaaagtg ttggaatagt ggttttttct atcactttac tggattctgc cgttttttct
     8401 ttatcagaaa cttcagtagt atttatcttc gtcgtctggc aaccacttaa cgcaaacaaa
     8461 ctgataagga ctaaagctgc tgcagttgca cgtttgcata aatttttgat tggttctgtc
     8521 atacacctct tcctttccat atagaaaaaa gaaagacttg aaaggccaat catatgatcg
     8581 acatttcaag tctctttatt aatcgatttt atctacttga tcgaaatcaa gttctgtact
     8641 ggtttcacgt ccaaacatat cgatgttgac tttcaatttt tctttttctc cgtcaacttc
     8701 tgttacttgt ccttctaatc cagcaaatgc gccttcgatg attttcacga cttcgccaac
     8761 ttctacttct agatcatttt gtcgcaggct cataccgata gaacgcaaga tatgattgac
     8821 ttcttctgga agtaatggtg ctggtttgct tccggctccg tgtgaaccaa cgaatcctgt
     8881 cacaccaggt gtgttgcgga caacatacca tgaagcgtct gtcatgatca tttcaacaag
     8941 tacgtatcct gggaatgttt tatgaacgat ttctttttct ttcccatttt tgacttcagt
     9001 ttctttttct tcaggaacaa cgacacggaa aataaagtcg gccattttca tactttgcgc
     9061 acgagattcg atatttgctt ttactttgtt ttcatatcct gaatatgtat gcaagacata
     9121 ccagtttttt tcaaaagatt ccattgaagg ctcctcattt cattgtaaaa taaaaaaacc
     9181 tcagtacacc cgaagttttt ctttcgcttc attatagcac taaaagtacg ttgtggctag
     9241 cgagttattt taaaatccag ccaaataagc tttggatggc tgtatccatt acgtaaaaca
     9301 tcaatccgaa aataatagaa gtttcgatga ctactaacgt atctttacgg agttgttttc
     9361 tgcttggcca agttacttgt ttgatttcat cttttacgct ttttagaaat ttcatgagac
     9421 aacctccctt gctactgttt atttcgtttc tttatgtaat gtatattgat tacaatattt
     9481 acaaaactta ttgatttcca aacgttcgcc gctttttcct tcactgactg attttgtgta
     9541 gttgcgagac ccacaaacgg aacaagcgag tgctgctttt ttctttgcca tttacttctg
     9601 cccccttgct gagaatcaga cttatacttc ataacagtat cacgtaactt tttacttgtc
     9661 aatttgtgaa ataaactatc tattgttttg gataaaatta tgatatgatt aatttgaaat
     9721 taagctaaaa tgagacaatt ggaggtatag cgatgctatt aaaaacactt gtatataaga
     9781 aaaaagatct gacaaccgtt acagagacta gtacattaga agaagcatta aaaattttag
     9841 aaacttccgg ataccgttgt gtgccgatct tagattcttc aggtaatatt ttccgtggaa
     9901 acatttacaa aatgcatatc tatcgtcata aagcaaatgg cggtgatatg acgcttcctg
     9961 tcactcatct tttgaaaaac gctacaaagt tcatttacct ggatacttct ttcttcaaag
    10021 tattctttac gatcaaagag cttccttata ttgctgtcct tgacagtgaa aatcattttt
    10081 atggtatttt gacacatagt acgttgctta atatgctctc tcaatcttgg agcgtagaac
    10141 aaggaagcta tgtactgaca attgcttcca caggaaagca aggagatttg gctgctattg
    10201 caaaaatcat ttcaaaacac agcagcattg ccagctgtat tactcttgat atcgaaaaag
    10261 acgaatacat tcgacgtaca ttgatcacgc taccggctaa cactgaagcg aaagtatgtg
    10321 aaacgatcgt caaccactta gagaaaaaga attataaagt ggtagaaatt gaaaatttgc
    10381 aaaaccaaga agcataatca aaaagcgaaa aaagaaaaca gctaatctgc tttctttttt
    10441 cgctttttat aattagacac gcttttcaaa atcaagcgcg cgatctaaat aatacatcaa
    10501 tggtgctgaa acagccatga cgataaactc acttaatgca agcgtgccat aggttgtcca
    10561 aaatgcttgg ccacctgttg gaactaacat ataagcaatc agtcccatgc tgatggtaaa
    10621 gaagatcgtg ttcaatacta aacgcatctt tacatttttc actttgtttt gcaataaagc
    10681 tgtcaggcct aaagaaagca atgtttggcc gccaccaaaa accacatcca tgataccaaa
    10741 accaaagaag gcattataga cgatgacccc gcctaaaact ccccaaagca atttacggtt
    10801 aaagacaact aaatgattca aactttctga aatacgaaac tggatcggcc ctgaggatac
    10861 aggcgcaact aaaatagtta acgctagata aagagccatg atgatgccat ttacaacgat
    10921 tacggataac cgttgtctgc ttttcgtttt ttgcattttc tctcctcttt tctcctagtt
    10981 tttttaacgc gggatggttg atgaaccgcg gttatgtgaa acaaacaata attataacag
    11041 acttttcatt tatttcaatc cgtcttatct gcttttaaaa aagcaaaagc ttaaacaatg
    11101 taaacgtttg ctaaaaatcg tgggatatgg tataaagtaa gtgtaagggg tcataagaat
    11161 tcccagtaaa gcagacgaag taggatctgc aagaacagaa ttgttgtgaa acttaaataa
    11221 ataaaaaagg atgtgggaat ttgagcaacc tcttactaga gaacggtcta gcaagcagct
    11281 gaagatctaa gtggacatgc cgaaccttgg aacttctcct tacgtaagta atggatcatg
    11341 cgcttgctag gcttttttgt gtttttcggt cttcggacct ttttcatttt cctagacttc
    11401 tgctataata accaagaatt aattttgtaa cagatttttt tgaaaaaaca agtttctttc
    11461 attcaaaaaa tagaaaaagc ttgctaatta ttggttaacc agcaaacagg agtattaaaa
    11521 tatcttgttt tattgaatag caggaggaaa tcatgaaatt ccattatcat atattgatca
    11581 atccatcggc aggcagcgga aatggctata aagtagcaga aagaatttta ccggtattaa
    11641 aaaataagca tattgactat acacttcatt atagtgaata caaaggacac gatgctgaga
    11701 ttgctgaaac tttggcaaaa gaaacattga ttccttggat agaagaagaa cagaaaacaa
    11761 tcgatacttt cccccttttg atcatcgtag gaggtgacgg caccttacat caggtacttg
    11821 atactttcta tcagatggaa gtagaattcc cagttgctta tattccagca ggttctggaa
    11881 atgattttgc tcgaggggca ggccttccaa aaaatcccaa aaaaggactt cagctgattt
    11941 tagcagctca atcaccagaa aaagtccaca taatggctta tgaagaaaaa ataagtgaaa
    12001 aaaaaggaat agctgttaat aatttcggta taggattaga tgcagctatc gtccatgcga
    12061 caaatcattc ttccacaaaa aagcgattga acaaatacaa cttaggatca ttttcgtatt
    12121 tattctctat tctccgtgct ttattcactc aaaaaggatt tccaattctg gtagatgcag
    12181 gaggaaaaca attaagtttt tcaaacgcat ttttatgtac agcaacgaag catccttttt
    12241 ttggcggagg aatcgcgatt gttccaactg ctgatgcgtc taaaccagtc attgattttg
    12301 tcgtggtcga acgaatcaat ttctttaaaa tcttgtggct cattctttta cttatacaga
    12361 aaaaacaatt gaaatcgaaa tatttccatc actacacaac aaacagatta cgtatcgttt
    12421 caacaacacc gcaacatggt caagaagatg gagaagaaat ggaaaaacga ccttttgata
    12481 tcacaataac cacaactaaa cagttgtttt ggtgttaata aaagaggttt tgtcagaagc
    12541 tacatctgga acaccgttta ttcggaaaaa aggactgtga cacgactttt gtcacagtcc
    12601 tttttttact atgcagttaa ttctttgccc aattgggttg ccatcgatag tttctttctt
    12661 tacccaaaat aaattggatc attgaaaaca ccgcagcaaa agcaactaag acacaaccat
    12721 tgaaccaaaa agattctgca aatgtttgat tgtaactgag tgtttcactg atcaagttat
    12781 tattttgaac aaaccaatat gttggtgtga atgccgctat tttgctaacc atttctggca
    12841 agtattctgc tggtacaaac accccaccga taaagcaact gcctgtgata aaaatatctt
    12901 tgatcccacc gctggtttct gagtttttta ccaatgaagt gatacaagcc gaaaagctaa
    12961 tgatcggcaa taaaaacaag aaagtattta aaatatgata ccataccgtt atatcccacg
    13021 aggtgtggat cactaacaga accattagaa gtaagaagcc actgaacaac agcagcgagt
    13081 aactaatcaa actaaaggtt actttgcgat tcaagtttcg tttggtaatg ggcgcactct
    13141 ggtttcgttt actgatctct ttgcgattaa acgctagatt gatgacgctg aaaccgctaa
    13201 aaatggatag aaacaaccca taagacaaga aattaaaggt tgtgcccgtc aacagctttt
    13261 tcatccgctg actatatccc gcacttagct caacttctcc agtaaccgag agtgccattt
    13321 gtgtctgttc catagctgca tcgattgttt tatcttcttc ttgaaacaga atcagtgttt
    13381 gcaaaaaggt gttcacttgc tgtgtaacaa ctgttttaga aaaggcatct gggcgactct
    13441 gtatcttgat cgtcgccatc tttcctactt cgacttgttc ggtaaagtct gcaggcagat
    13501 gtaagataat gtttacacga ttaaaataaa gagcatcatc gatttctttt tgtgaggttc
    13561 catccaatgt aacgactgtt tccttgtcat tcaaatattt acgaaggcca tcgactacag
    13621 gcgactcttc ttcactaatc aaggcgattt tcgcatcttg cagagaggta ttttcaacat
    13681 caatattttg cgcaaaaaag aatgtggcaa caacagtgat aattacacct atcagtaaat
    13741 tcgatttatt tgctttaagc aatgtccaaa tcgttttata aagcgtcata acgcacccct
    13801 ctttccatcc aagcatttcc taacgcaaaa aggaaaataa atccgatcaa ccatagaaga
    13861 ttggtataaa aactagccaa atcagtgtag aaataaagtt tatacaaact ttcgctgatc
    13921 aagttgacga gatttaattg accaacaatc ggaatatgaa gatcaatcca atacttcact
    13981 tgttccgacc ccatcatacc agcaaaaaag ctcatcgcaa tcgtcactga aatcaagatg
    14041 ctatcctttt gcaccagatt catttttggt atcaaattac caaccaatgt acctaacaaa
    14101 atcgcacaca acgaccccag agcggtaaca atcatcaacc attgccaacg ttcaccaaag
    14161 tctacttgat agataaaacg aaagacagct aacataatat aaatctctgt caaaacaatc
    14221 gtaaagcttg ctgccaaatt agcgattgaa actaacgatt gctttctagg aatcaaggac
    14281 aagcgaatac catttgacga ttgatttgct tgctgatcct gtacattgcg gaccccccac
    14341 atcgtcccgt agagaatcgc cattccaatc agagtgaaga aataaaaact tttgaaactc
    14401 atattacgac ctgcatgaac ttcttgaaaa gatacttctt gttcaaaaac agtcatgatg
    14461 ggcgcgagat caacgttctc cacttctgcc actttactcg aaattatacc aatacgctgt
    14521 aaaaattgat ccatgacgtt tttcatcaac gtctgactca ttcctgcttg acccacatgg
    14581 agcgaaacag atgaaccatc aatgagataa aaaccagcca aatcatctgc atttagcttt
    14641 tcattcgctt ctacttccga tagttcctgt acttcaaata atggtttatc attgacttcg
    14701 acttgttcta agactgtggt aaaattttcc gaaagcgctg tttgatccgc tttgattaca
    14761 attccagtat taatcgtttc aagattgcca ccttgatcaa tctcgccaaa ggccgccata
    14821 aacatcaatc ctaaaagaat tggaaaggcc aatgtccaaa acaacatgga tttatttcgc
    14881 agcagtattt ttgtgcgata tttataaaaa tgccaaaaca ttatttcccc tcctctagtc
    14941 tctcaaatcc ttgccagtaa tctctaaaaa gacatcattc aaggacgctt ctttggttgc
    15001 tatttttccg taactgatct tttcttcttg taagattgta agaatcggca acaatactgt
    15061 atttagttca gtagttgtta cttggagctg acctttttta taagcgattc catcagaagc
    15121 tattgttcgc tgaatcgctg acaacacatt ttctgggagt aatgggatgt cgatcgtcaa
    15181 acgatccgcc gtccgtacca tatcttttag agattctttg gttcctttag caatcacctg
    15241 tccttgatcc atgatcacga tctggtcgca aagaatttct acttcttcca tgtaatgtgt
    15301 tgtatagaca atggttgctc cttgtcgatt cagctccttg atactttcta aaattttatt
    15361 ccgactttgg gggtctacag ctactgtcgg ctcatctaaa aaaattaacc gcggcttgtg
    15421 ggcaatccca catgcgatgt tcaaccgacg tttcaagcca ccactaagtt ctcctggacg
    15481 aaacgaaaca tatttttcta atcccactaa ttgaatcacc tcttcaatca aggctttcct
    15541 tttctctttt tcggaaacat ataaaccgca aaaataatcg atattttctt gcacacttag
    15601 ttcgtcaaag accgcaacgt cttgaggaac gaccccaatc attgccttga cagcataatt
    15661 ttcaggagtc attgttgtcc cgaacaattt aatggttcct ttgtcataat ttaacaaaga
    15721 aagcatacag ttgatggcag tcgatttccc actgccgttt ggacctaaca gacctaagac
    15781 ttctccttct tgtacttgca gatcaaaatg attcaatgct acaaaatctc catagcgttt
    15841 gactaattta tcaatttcga taatcatcat gaaaaactcc ttccaaattt cttgttgatc
    15901 tgactataat aaagtgcaag aaaagaaact agtgacgatt ggctaaacca cacatgacat
    15961 ttgtcacaat gaaggagtct gctatgcata aatctcggct actcaacgaa actagctttc
    16021 tactggttat ctcattgctt ttgctggtaa gtcaaggatt cgttgctatg caagttatct
    16081 atttattgat cgccgtttta ttcactggtg tcagttattt actgcctaca aagccaaatt
    16141 ggattttcca agttattcta tttcttttat gtgccttttt acctgatctt gtcctgtttc
    16201 tgccagcgac gatgcgagtg atcgcccctg aagaaagcca ccttgattac ttgtttttgt
    16261 taggtttttt gttgatttcg acggttggta atcatccccc catcaaggtc gcctttgtcg
    16321 taattttgct gtttttttcc ttttacttac gaaaaaaaga tcaacgaacg accgatcttg
    16381 agaaaaagta cattgtctcc aaagatactc attgggaaaa acaacaagag ttatcggaac
    16441 aaaataaagc attggccctg tcacaagaaa cacaattagc cttgcaaatt gtggaagaac
    16501 ggaaccgaat tgcccgagac atccatgaca atgtcggtca tctgctgtca agtgcgattt
    16561 tacaaattgg tgcgcttgaa atgatcaatc aagaaccaaa actaaaagaa ccattagaaa
    16621 atttaagtgc caccgttcac actgggatgg atcggattcg tcaaagtgtc catgacctcc
    16681 atgagacatc gatctctttt caacactcct tagagtttct gatcgctgat tttccttctt
    16741 ctgttacgat tgaaggaaac ttgtttgaag gattgaatga aacgcagcaa aactgcttct
    16801 taatggtcat caaagaagcc ttaaccaaca gtatcaaaca tagtcatgcc aaaaccgttg
    16861 ttttacattt tcgaacgttg ccggcctttt atcgcttgca aatcacgaat gatggcacca
    16921 gcccacaaaa aaattctgct cccggtattg gtttgaaaac gatgcgtcaa cgtgttcaag
    16981 aacaaaaggg acaagtccat attttccaag aaaaccagca atttcagtta acgatcattt
    17041 taccaaggga gggacaccaa tgataacagt agtcattatt gatgatgatc catttgtgac
    17101 gaaatcgtta caaaccattt tagaaagcac gaaagagatc cgtgtgttag gcattggtca
    17161 ttgtgccaag gatgcgcgaa acccatcgtc ccgatgtttt gctgacggac atccgcatgc
    17221 ctaaacaaac gggcatcgat gctgccaaag aaattttggc taaatttccc aaagccatcc
    17281 ttttgctttt gacgacattc aaagatgaag aatacatccg cgaagcattt tccatcggtg
    17341 tcaaagggta tttaatcaaa cagaacttgc aagcgattat tccttctgtc aaatccgctt
    17401 ataatggaca ggccgtattt ggtaatgaaa tcatcgagac tttcactcaa atgatgaaga
    17461 ataaaccgac gattgatagt catgcttatg cttcttttag tgaacgtgag cttgcaatca
    17521 tcaaagaagt agctgccggg aaaaacaata aagaaattgc agatgccttg tacttgagtg
    17581 acggcactgt tcgcaattac atcagccaat tactagaaaa gctagattta cgggatcgca
    17641 cgcaattggc tatctatttt tatcagcatt tgcaataagt cttatctaac acaaaaaaac
    17701 ctgaatgatg ctccttcgca tcattcaggt ttttttcaca tcttctattc aattgtcccg
    17761 caaaccattt cctcacgatt gaaagaatca aggattcgca gggctgccag gattcgttgg
    17821 attgttcggc gtgttaggcg gaaaaatagg cgccttgtct aacgtttttt ctagttttga
    17881 ttcttcacga tcgtctcgtt ctacatcagg actttcattc aatttgaatt ctttttccat
    17941 ctcatctaac tttttaaagt cattgccaga ttcttttgct aatttcgcta atttatcttc
    18001 ggtttcttta gccataaagt aacgcccccc ttttgatttc agcttagcat atcacactga
    18061 aaaaacaaaa gaaaacgcta accaacgatc atttttagct atttctcatc tttaaaatca
    18121 agcatttttt gccggtataa aatcgtaggg agaactgttt tccataccaa tcatcggatc
    18181 tactaactgg ttatcgatca cttctgctgt aagaacgaaa tctttagaaa cagcaggttc
    18241 tacctcttct ttcttttctt ctccaacaaa tgaagaaaac agatctggtt ccactgtttc
    18301 cattacttgg tttttcgttt cattcgtccc actgtcatct tctacaggta gcttttcttt
    18361 tacaacccgt ggctcttttg tatagttccc atcttcaaat ggatcatttc cgaccaaaga
    18421 atcttcataa gctgctagtt tggtccggag agtgatattc attttatcat tatccatgat
    18481 ccttgatttc aacgtagtca tccggcttgc tgattcattc gctacacaag tgacataggc
    18541 ttgctcttcc cctaacaaaa tcaacagttc cttactgcga gtcactgccg tgtagagcaa
    18601 attacgctga agcatccgct gatattgatg gaccatgggc aaaataacca tcttgaattc
    18661 actgccttgt gatttatgga ttgagcaaca ataagaaaga gtgattttat tccattcgtt
    18721 tcttttataa gtgacctcat ttgcatcaaa ctggataact aattcatcca ctttatcttc
    18781 agaatctttt gccaagatga tacccgtgat ttctcccata tctccattga atacattcaa
    18841 ttcgggagta ttgactaatt ggaggacttt gtctcctatc cgataaacgg tgtcgttcca
    18901 atgtacttcc ttttttccag gtttccctgg attgaatatc tcctgcatca ttttatttaa
    18961 cgcatcgatc cctgcaggtc cccgatacat tggtgctaat acttggatat cttgtgcacg
    19021 gaatccctta tttttcgctt tttccacaat tttagagatc aagggttcaa tttgataagc
    19081 atcacttcgg aaataggaac gatctttttg attctttgtg aaatcttttg gcagacgtcc
    19141 ttctttgatc tcatgggcaa gaggaataat actagaacca tcaccttgcc gataaatctg
    19201 attgagttcc attttgggaa tttgttcgat ttccaaaaga tcatggagta cttgaccagg
    19261 accgacagag ggaagctgat ctttgtctcc tactaagata acttgcatat tcgtcggaat
    19321 cgctttgaat aatgtgttag ccagccatgt atcgaccata gacatctcat caacaatcaa
    19381 aagtccgcct tctaattctt tcgtactgac tgaaggtgtt ttttcccgtc cattcagccc
    19441 cagaagacga tggatcgtac tggcaggcag acctgtcgtt tcgttcattc gtttagctgc
    19501 tcggccagtt ggtgctgcaa gtagaatagg aaaaatttct tgggtatatt ttgaaggatc
    19561 caattccagt ccgttcaact ctgcaaaaag attgacgatt ccgttgatca cagtagtttt
    19621 ccccgtacct ggtcctcctg ttaaaataaa tagaggggaa cggattgctt cagcgatagc
    19681 ttgttcttgc gaaggtccat actgtatgcc gaatattttt tcgatacgcc gaatattctt
    19741 ctgcacttct ttttcaggat aatggatttc ttttttacga ctgagaaggc gctggatcga
    19801 attaccgatc ccccattcag aaaagtacaa actgttttcg taaagattag tctcttcttg
    19861 ttgtatcttt ccttcttcaa caagttggat aattacagta gcaacctgat caggctggat
    19921 ttcaattggg cgacttgttt ctaaaatacg gatcgtttgc tgaagcaatg tctccgccgg
    19981 tacgtatgta tctcctgttt gaactgcatg ctgaaaaatc tgatgcaaga tagctgctcg
    20041 aattcttctc ggtgaatctg ctgcaatacc gatttgttcg gctagattat ctgcacgttt
    20101 gaacccgatt ccttctatgt cttcgactag ctggtacgga ttttcttcga tgatatccaa
    20161 agactcgttc ttataggcct ggtagatact gaaagctaac tgactaccga acccgtaacg
    20221 attcagtccc atgatcactt gatccatccc gtggtttagc cgaatcgtct cagcaagcat
    20281 ttctcttttt ggcttcgtca aaccggagat ttgttttaat accgaaggat cagcaatgat
    20341 tttttcgata gcatcttctc ccagcaattc tacaattttt tctgctgttt tcttcccgat
    20401 tcctgggaat ttttcgctgg aaagatacgc tacgatccca tttgcagttg ttggcttttc
    20461 ttgctcatat ctttcgagtt taagctgcct tccgtattta ggatgatcca ctaattctcc
    20521 ataaaaacga taagtctcat tttcttgaat atcgccgaaa cttccggtga ctacaatctc
    20581 tttttcacgg taatcagctg tggtttcact gatgtgtacc aaaagcactt tgtaaaaatt
    20641 actaggattt tgaaaaaaaa tcgcggcaac tgtaccaacg aaataaggca tttcttctgg
    20701 ctgcatcgga agccgcctcc ttcttctata gtaaaggttc tggtgctgtt tcagttccta
    20761 aaaaatctgt ttggttccat actttcagtt catatggcaa taatctgcaa ggctcttcag
    20821 tctctaaaat cgtcaaacta ctattgaaca atccacccat ttcacgcaac tcacttagct
    20881 cttttcctgt catccattga atggctgcag ttaaagaagc tccatgtcct acgaataaaa
    20941 gtgggccatc tttatgtcgg gcaaccgcat ctgctacaac agtttcgata cgtgtgattg
    21001 ccgattcaat cgtttctccg tgaaaaggag aaggatcata cagatctaaa tgattacgca
    21061 aattcggcag attatccgga tatttctggt acatttcatc gatcgactga ccttctaaag
    21121 tacccagccc tagttctctt agcttatctg tataaaaaat ctctaccgga cgagcaagct
    21181 ctttgttgat accttctgct gtatcacgtg ctcgctttgc tgtactggaa taaattgctt
    21241 taaaaggaac atattttacc tttttcccaa atgctttgat ttcttcgtaa ctttgtggca
    21301 aaagcggaga atcgccattg ctcccttgaa aacgtctttc ctgattccat tgtgtcttcc
    21361 catgtcgggt aaaatatagt tccatacgca gcaaactcct gtctttcttt tattttactc
    21421 tataataaac tgtctaatcc agcttgtcat tttcatagtg atgcgtcaat tctaaattag
    21481 ggaatccttg ctggcgaagt gcttcataca ctatcattgc agctgtattc gataaattca
    21541 atgagcggac atgctcatca ttcataggga tgcgtaaaca cttttcttcg ttttcacgca
    21601 taaatgtttc tggcaaaccg gttgtttctt ttccaaataa aaagaagtgc tcttctccat
    21661 cagcaaaatt ttcgtcacta tatactttat gggcaaattt tgagatcaaa tgtagtttac
    21721 gattacctaa aaatgttaaa aaagcttcta aattactgtg gtaagtaata tttacatcat
    21781 tccaataatc caaccctgcc cgttttagat gtttgtcatc agttgaaaaa cctagtggct
    21841 cgattaaatg aagcggagta ttcgtggctg cacacgtacg ggcaatattt ccagtgtttg
    21901 cagggattaa tggttcaaat aaaacgatat gattcatcag gatcattcct ctcatattta
    21961 tgttcgtttc tattttctga caatttgatt tttgcataaa aaaaaacgta tcaactcggt
    22021 gtcagtcact gcgagtcgtt acgttagtga agctcttctc actaactttt atcagaacag
    22081 gaacctgata aaaaccaatg aaaaaacaac ttgttgctaa tataacaccc tcaacttttt
    22141 tttgcaacct ctactcatta aaaactgcta gaaaaacgtt ttctcttagt tccttttaat
    22201 aattctatgt caattgtaat cttcttcaaa ggattcttat ataagtctgc tttgattcgc
    22261 tcttctacct gccattctaa aggtgacatg gccaaaagat ctttttgatt ttcctctggt
    22321 atctcaaatt cataggttac acgctgacgt tcagttaatt tcattgcttc agcaaacttg
    22381 gctactacac gttcattgga ataactctgt ttttcaggtt gattcggata aaaagcctga
    22441 cgtagttcct ttaaataatt ttcttgtggc accaccttca acacttctcc atcttctgag
    22501 agtacacgtt ggaattcttg gtaatgagaa ggcgaaaaga tatttaaaac cgcgttgaat
    22561 gtttgatcag caaacggcaa attggtcaaa tcagctacac accaaaatgc ttcggcagat
    22621 tgttctgtag ctgcgtagac tccttctttt gaaatatcaa atccaacagc attttgaatc
    22681 tttttcaatt ttgaaagttc attcaagaag ctaccttctc cgcagccaac atctaatagc
    22741 gagacttctt caggtaaatg ctgcgcaata gtctcaataa cgggctgata catgccagat
    22801 tggatcattc tacgccttgg aacgaacatt ccttgatcgt attctgtttt aaccgcatgg
    22861 gataaaaaat aaagtgttcc ttttttggaa aggtcaaaac ggtgattatt tttgcatatc
    22921 aagccattat cagacttttt tacttcttct tggcaaaccg gacagcggaa cagctgatga
    22981 ttttctgcca aaaactggcg tcctcggtca atttttttta acatagttcc ccctcatttc
    23041 tgttttatct taccgttaga tgctcacttt ggcaactgct aaaaatatga tacaatgcct
    23101 agaagaaagt gaaagataaa ggagaagatt agatgatcaa agaattttgc gctgaaaact
    23161 acacatctat tcctctagca attgctagag gagccgatcg gatcgaattg tgtgacaact
    23221 tagcggtcgg tggcacaacc ccgagtactg gtgtgatcga agaaacgtta agttatgctg
    23281 gggaaaaaga tatccccgta atgacgatta ttcgtcctag agggggcgac ttcgtctata
    23341 acgatatcga attgaaaatc atgcatactg atttgattga agcaaagaaa ttagggacgg
    23401 atggcgtagt atttggttgt cttactcctt caggctggct agacgaagag gccttagaac
    23461 tattgatcga aacagcagaa gggttgcaga tcaccttcca tatggctttt gacagtattc
    23521 ctgaagatcg gcaattcgaa gcaatcgatt ggctggtaga acatggtgtt gaccgtatct
    23581 tgactcatgg cggtcctgct gacaaaacta ttgtagaaaa tttcccacgg cttaaagaat
    23641 tgattgccta tacagatggc cgcttaatca ttttgcctgg tggtggtgtc actgcagaga
    23701 atgcagcaca tgtagctaaa gaattgaacg taagcgaagt acacggaacc aaaatcgtgg
    23761 atcttcagtt ataatcttat aaacaaaaaa acatttgcaa caggcataat gcttattgca
    23821 aatgtttttg tttttttaca taaaatagcc cataaataaa gaagcaatat tgaaataaat
    23881 cagtacactc gtcaaatcgc tcaaagtcgt gataaaggga ccgcttgcta ctgctggatc
    23941 aaatcctaga cgatccatta gcatcgggat taaactacct gcaagattcg ccactgtgat
    24001 tgcaaatagc atagccatcc ctatgacaaa ccccaagata aaattatgtt tccaaaaacc
    24061 tacgattaga aaaatcgtga tccccgtaac agctcctgtg acaacgccgg tcaagacttc
    24121 agccaaaaca agtcgaacaa atccatgatc tttctcatca gaaatcgcaa gtcgacgaac
    24181 agccacagct agcgactggg ttccagcatt accggcagtt cctgtaatca gcgaaatgaa
    24241 gactgctaaa atactcgctt cacttaccaa gtcttcatag tgactgatta aagaagcggt
    24301 cgacatacct aaaaacaaca gagtgatcag ccaaggcaaa cgtcgagacg ctgcctttac
    24361 tggattttca ttaatttctt ccacattgac cccggcaagt cctgaataat cgctagcagc
    24421 ttcatcatca ataacgtcga tgatatcatc gactgtgacg attcctaaca aatgatcatc
    24481 ataatcggta acaggaagag ctaagaagtc ataatctcta aatgtttgtg ccacatcttc
    24541 ttggtcgtcg cctacatgaa ctgaaagcac tcgttcgctc atcagatcag aaatcattgc
    24601 gtcgtcatca ttcacgatta ggtcgcgcag agaaataacc cctactagct gaccttcttg
    24661 attaacgaca tagatgtaat agattgtttc agctacatct gcttcgttct tcagcacgta
    24721 catcgcagag cgaacagttt gattggctac gatcgaaaca aattcagttg tcatgatcgc
    24781 gccagccgtt tcatcctcgt aatggagaag ttccttgatt tcactggcat cgtctgccga
    24841 catcaaactt aaatatttag caatttgctt tttatccagc gtattaagca agtcaacagc
    24901 attatctgta tacatctcag aaagcatatc agctgcatag ctaggacgca tttcatctag
    24961 gtattctttc atatgttcgt tgtcttcttc aatcacatcg aacatatccg ctaattcttt
    25021 aggcgacaga taggaataga tcagctgcct gttctcttct gtaagagatt ggtagaattg
    25081 cccctgctca tagatatgca tctctaaaaa actgtttctg aatgcctgaa tattattttc
    25141 ccttaaatct tgagtcaact gggcaaatct ttcctctaat tcttgatttt catccaaacc
    25201 aatctcacct cgccttattc ttcaaaccgt ctcacaactg cctccatgtc tgcggctaaa
    25261 ggctgcttga actccagcaa ctcttctgta aatggatggt aaaaacgcag atcataacaa
    25321 tgaagggctt gtctttttat tcccagatcc attcgcccgc catacatatc atcaccgagc
    25381 agggcacagc caattgcgga aaaatgaact cttatttgat gtgtccttcc tgtatgcagc
    25441 tggatatcaa ctaacgcgat ttctgttagt cgcttctcta tccagtactc agtctgtgcc
    25501 gaacgtcctt catcagagac cattcgcttc aatagcgaag aataatctcg ggcgatcggc
    25561 aaatcgatat gtccatgtgc cgataaatct gaaagccttc cactgactaa ggcctgatat
    25621 tttttcacaa acttcttttc acgaagttgc atatctaatt ttgcgtgcgc aaatccatgc
    25681 tttgcaaaaa gcatcaagcc agatgtatcc cgatctagtc gcgtcaccac atggattact
    25741 tggttttcgt aaccttgttt tttataataa gcctttacac gattagccat tgtcccattt
    25801 ggatggtatt gggcaggaat agacgaaacg cctgctggtt tatttactac cagaacgtgt
    25861 tcatcttcat acacgatatc gatcggtgtt tcatccaaaa gtacggtttc atgttctcct
    25921 tcagcaggaa tcacaatggt taccttatca tccttagcta gagaaaacaa gacattttct
    25981 acttgatcat taactttgat ttgaccgcct tgaaatttta ttttcgctaa cagacccttt
    26041 gagatccctt tttcttttaa aaaatatttt acttgctgag aatgatcttt ctcataatcc
    26101 catgtaaact gcatatcaat cctcactaat aaaggcatct ttcacacgat gccaaaaatg
    26161 catatgtcga taagaagcaa aatggatccg ttcttctgct attcgataat aaattgagcg
    26221 gatatttgct tttgcgacat tcaattgatc aaccgttaca agataatctt ctgtattttc
    26281 caattttatt tctagccatt catcatgggc aatcacgatc ggagaaccca aagtacgaaa
    26341 cactcgatta ttcagtgaag caatctctgc caactgaaag gcattgatac taggatggat
    26401 cacagcaccg ccgacacttt tattatatgc tgtcgaacca gtaggcgtag aaatcgtcaa
    26461 tccatctcct ctaaaacttt caaacagctc gtttttgatg tatacatcgg ctaccatcgt
    26521 acgattggcc cgtttaatcg ttgattcatt cagtgctaaa aaatgctggt ccggtgtttc
    26581 atccaaataa ctgatccgaa catccagcaa gggataacta acactttgtt cccggttcgt
    26641 tcgtaagctg tctactagtt cttccagctc gtaatcccgc caatccgtgt aaaaccctaa
    26701 atgacctgta tgcacgccca agaaacgcac atcattcaga caatgactgt agtgatggaa
    26761 cgccgacaat aatgtgccgt ctccgccgac tgagatgacc aattctggct catgatcatc
    26821 tcgttgaatc cctgcttgtt ctaaaagtgc gttcaaacgt tctgtcactt ctatagtctt
    26881 tgcttcttta ttatgaacga tcgctacttt catcccctgc ctcctctctt tcgctttctt
    26941 tcttcaaaag cgttcgatag tagacatcat ctgattttcc tcttccatgg gagaataacc
    27001 gctgtgcttc ttggatttct tcacggatac tggacatctc ttcatccaac tgataggcag
    27061 cttctgccgc acgctgaagt cgttcactca tttcttctgg aaaaacgcct tgatatttat
    27121 aattcagcga atgctcaatc gttgcccaga aattcatcgc aagagtccga atctggattt
    27181 ccgccaaaat tttcttctca ccgctgatca gctgtacagg atactcgatc accagatgat
    27241 aagaacggta gccacttgct tttttatttg tgatgtaatc tcgttcttgg agaactttca
    27301 tgtcttttct tttacggatg atctcaacaa cttgatggat atcttctaca aactgacaca
    27361 tgatccttaa cccggcaata tcagacattt cttcttctaa acgtcccatt ggaatatgcc
    27421 gtaattgtga ttttgttaca atactatcga ctggcttgac tctcccagtg acaaattcaa
    27481 tcgggacatg tcgattttgt tcacggaact gtttgcggat cccccgcagt ttcactttca
    27541 attctgatac agtttgttca tatggtgcta aaaatgcttc ccaatctcgt tccatagctg
    27601 atacctctac ttcattaaca ttcattgttt attctaccat atatgcaaag ttttttcgta
    27661 ctcttgattt atgcattgac caaaaaaaga aaattaggca aaatagacaa aaaggagtcg
    27721 atcaaatgac acaaatgctt gaaatcgaat ataaatctat gctgacaaag caagagtacg
    27781 agatattcat cgctcactat caattaacag ataaagattt ccgtgtacag actaatattt
    27841 atttcgatac cgttgatgaa cagctgaaga aacaaaattg tggcctacgg atccgtttcg
    27901 ttggtcatca agctgaatat acattaaaaa cacctgctga aaaagggcgt ctcgaaacaa
    27961 cggatacctt tataacagaa gaagcagaag catttatctt cgaaaaacgt ctgcctcgtt
    28021 caggcgcagt ttttcaaaaa ctttctgatt tgaatatcga tcctgcttca ttaatccaaa
    28081 ccggaaagct tacaacaaaa cgagctgaat tccctattga agaaggactt ttagctattg
    28141 atgaaagctg gggagacaat ctacacgatt ttgaactgga actagaggta ggggatgcat
    28201 ctgtgggaaa aattgctttt ataaattttt taaaacgttt ttctttacct tatcgtcctg
    28261 ctaagaacaa gatccaacgt atgcttgaag ctaaaaatta gaaacctttc attttcacaa
    28321 ggcacttgag ttcatttttt tacttttttc tgttaagtta taggatgtga aagaatctag
    28381 tcactagttg tatagaatct attttggggg agattcatat gatcgaaatc tatttatttg
    28441 ttaatccttt aggggaatac tgtttcgaaa tggaacaaca gttattacaa tttatcgaag
    28501 aagagtacgg gacaccatca aaagaaaaga tgcaatttcg ctttcttcct ttggtcaatt
    28561 tgcagacaat tggggatgtc atgcaacaaa aaggaatttc tcagaacaat cttgaggaac
    28621 gtaatcactt attctcaatg acttattctg cagcattgga ctgcaaagcg gcgcagtttc
    28681 aaggaaagaa aaaaggccgc cgttttttga tcaaattgca agaagcagtc ggctgtaatg
    28741 acataccata ttctcaagaa cttgctgaat ccatatttga agaaatcggc ggcgatttga
    28801 atatgtttaa agaagatcgt cagtctgact tcgttaaaga agtattcttt tctgatcaaa
    28861 aaattgctcg ggaaatgggc atcacaaaac acccttctgc agtcgtttac aattatgcct
    28921 gcgaccgtga ttttggtgtt ttagtagaag taaaaggtac aagtagcctt tggagaatca
    28981 cagagctgtg taaaacaaca gataactcat atcaagtttt taatggtgaa catttacata
    29041 caaatgattc tcagttccat tcaagaacta gccatttaca cttgctttct aattaaaa
//
LOCUS       DAFENC010000033        27497 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.033, whole genome shotgun sequence.
ACCESSION   DAFENC010000033
VERSION     DAFENC010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27497
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.033"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(716..3865)
                     /locus_tag="LP493_001881"
     CDS             complement(716..3865)
                     /locus_tag="LP493_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HBL2134028.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDSFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKILMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMEPVKKESYLDPTVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSVQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSSTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKANHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(3879..5123)
                     /locus_tag="LP493_001882"
     CDS             complement(3879..5123)
                     /locus_tag="LP493_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBL2134029.1"
                     /translation="MSNDIQPEIRFPGFTEAWEQRKFECLLDKKDGVRRGPFGSALKK
                     EFFVSNSNFVVYEQQNAIYDNYETRYKITEKKYNELIKFKLEPGDFIMSGAGTIGRIS
                     RVPKQIKPGVFNQALIRLRINKEITDSEYFIQFIRADFMQRKLTGANPGSAITNLVPM
                     SEVKKWIVQFPILEEQKKIGNFFKQLDDTIALQQRKLDLLKETKKGFLQKMFPKNGAK
                     VPEIRFPGFTEDWEQRKFKEFSKKTGKKNTKDLDFPAYSVSNKAGLISQTEQFDGSRL
                     DDLEKTNYKFVEPNEFAYNPARVNVGSIAFNNLGMTVIVSSLYVVVKMSEDLDNEFIL
                     QFIKSPTFIKEVKRNTEGSVREYLFYENFANIKFPFTRNKEEQQKIGAFFKQLDDTIA
                     LHQRKLDLLKETKKGFLQKMFV"
     gene            complement(5116..6708)
                     /locus_tag="LP493_001883"
     CDS             complement(5116..6708)
                     /locus_tag="LP493_001883"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HBL2134030.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLANFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHE"
     gene            complement(7218..7943)
                     /locus_tag="LP493_001884"
     CDS             complement(7218..7943)
                     /locus_tag="LP493_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134031.1"
                     /translation="MKKKKLLWICLAILLIIGGIEIFTTYRLKTNQPKQYVSDMLNII
                     EEIDSEMKAFSKTSMDLGERYDFKGFMEDKMDEVSSREIPEGTPKAVRDTKDTLLEAI
                     DNVNTALLTNDVKLLEQGQLCFSIAQAIYTEFLDGNIKEKSLNEKLNSFVETYTAIPP
                     TWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNAVTEKVGKDIPLRLLENGKK
                     DYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(8097..8423)
                     /locus_tag="LP493_001885"
     CDS             complement(8097..8423)
                     /locus_tag="LP493_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134032.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSRMTGSSGLEKSSVPLVTQ
                     ILQEQYNLNRTCDDVTITHDNGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            complement(8460..8825)
                     /locus_tag="LP493_001886"
     CDS             complement(8460..8825)
                     /locus_tag="LP493_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBL2134033.1"
                     /translation="MYCRKCGKEITNESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEQMGTILM
                     IAGVAGAIFGVLLGMSMSY"
     gene            complement(8862..9077)
                     /locus_tag="LP493_001887"
     CDS             complement(8862..9077)
                     /locus_tag="LP493_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2134034.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            9206..9541
                     /locus_tag="LP493_001888"
     CDS             9206..9541
                     /locus_tag="LP493_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2134035.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAKKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVDIDYEEEFLALYRSLSTEDAIRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(9617..11614)
                     /locus_tag="LP493_001889"
     CDS             complement(9617..11614)
                     /locus_tag="LP493_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134036.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFKHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVRDNSVKNALIENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPIYQFTSVTRDDGRRVRNRRDPIILN"
     gene            complement(11712..11987)
                     /locus_tag="LP493_001890"
     CDS             complement(11712..11987)
                     /locus_tag="LP493_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2134037.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            12219..12953
                     /locus_tag="LP493_001891"
     CDS             12219..12953
                     /locus_tag="LP493_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2134038.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            12992..14134
                     /locus_tag="LP493_001892"
     CDS             12992..14134
                     /locus_tag="LP493_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL2134039.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(14762..15247)
                     /locus_tag="LP493_001893"
     CDS             complement(14762..15247)
                     /locus_tag="LP493_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HBL2134040.1"
                     /translation="MVRRVFFSFHYADVTRAMVVRNSWTLRGTKEAGFVDKAEFEKVK
                     RNGDIAIKNWIDNQLIGTSVTVVLIGKETLDREYVKYEIQESYKRGNAILAVNIGKIK
                     DFNQMTTTSQSVIKIIGQKPDGEYLWFDEIIDGQYDYISDDGYNNLGTWIDSAAYKKG
                     K"
     gene            complement(15249..16685)
                     /locus_tag="LP493_001894"
     CDS             complement(15249..16685)
                     /locus_tag="LP493_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HBL2134041.1"
                     /translation="MDKKVLIKRFSEAIEKGNAAIFAGAGLSMSQGYVSWPELLNDPA
                     TEIGLDSKKETDLVTLAQYYKNENGGSRGILNQILMDNFGEELEISENHRILASLPIE
                     TYWTTNYDHLIEKSIREAYKNPQVKKNYTQLATTNPNVDTIVYKMHGDIDDVSSTVIT
                     RDDYEKYDDDSYALFKETLKGDLLTKTFLFLGFSFTDPNLERILSDIRWVLRENQRPH
                     YCIMRKILKENFVDSEDFFDQERYNYELTKRRLQINDLSRFSINVVEVDDYSEITDIL
                     KSIRKKYLRKTIFISGSAVDYTPFTSESKGLKFVEKLAYRLSESGYRIVSGYGLGIGN
                     SIVSGVLKQRRNLRKNNIQDVLSLRPLPLDMPHEWRRYRENIIAESGISIFVFGNKLE
                     SGEIVTADGMIEEFELSVQNENIVVPIGFTKGASKVLFDKIQENFSDYFDDSLKSKFQ
                     ALEKLDTEGEVDKKVEQIVSLINSIQED"
     gene            complement(16718..17569)
                     /locus_tag="LP493_001895"
     CDS             complement(16718..17569)
                     /locus_tag="LP493_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HBL2134042.1"
                     /translation="MYKAYELDFTNADLNAFSSSSQSYTHVVNQIDHNQKSINKRIEN
                     LFESENDLVDYYSKDSKILDADEIIKDWFPTIKADIFISHSHADEKLAIRFASWLFEN
                     FGLTAFIDSSVWGYSSDLLKKIDQKYCYKEQTKTYDYDKRNVTTSHVHMMLSTALNNM
                     IDSTECLFFLNTPNSISLSNEITNEQKFTYSPWLYSELTTASIVEKKNPRLESNPQMS
                     TEDVRSIIKHYSSQENLQIKYSLNLSELTYLRKADLKKWALDAVECTKGSNTLDILYK
                     NTIFTNL"
     gene            complement(17725..17970)
                     /locus_tag="LP493_001896"
     CDS             complement(17725..17970)
                     /locus_tag="LP493_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2134043.1"
                     /translation="MLFLKEEKIIDKENVIGSNIRRVRLEKGIGQTELIRDLQLRKIA
                     ITRETLVKIEGGRQHIKLDQLKAIKDILQVSYEDLLQ"
     gene            18075..18848
                     /locus_tag="LP493_001897"
     CDS             18075..18848
                     /locus_tag="LP493_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134044.1"
                     /translation="MKKFAIILTCALLIGTISGCTTSDTSSTSTETSTTTSEKNYPIH
                     FFPVPDGFEAYYHDKKLDVPLSETESTEKILPIEIERNQDDIKLKADLPLLNSTQIDR
                     HENIKVNIEKGALAQLYTEKVEQFFEAGANKDFSKISDYSDNFFNETQDEITNSTFMA
                     EDMYNMKLKKIKSYDYPLNLTLNKGILSFVLAGYVDYEYTADYLETPLQHDNNDINFR
                     FIYNSKSKTWLVDQLSTINTGFHELPKPDNETALVIKTF"
     gene            complement(18901..19215)
                     /locus_tag="LP493_001898"
     CDS             complement(18901..19215)
                     /locus_tag="LP493_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134045.1"
                     /translation="MADENKVVPLETLVINKEEFEQLFLDFFVQYDRIYDFSSSLDLF
                     ELEAEIIENSREENGKIIISVEKFNELFSETFEIDTDYYQPQEVFQSFRNQIIRSGKT
                     VN"
     gene            complement(20734..20952)
                     /locus_tag="LP493_001899"
     CDS             complement(20734..20952)
                     /locus_tag="LP493_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134046.1"
                     /translation="MKLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKHEIKNNLKYCYLEKSEEIIHELNGF"
     gene            complement(20967..23594)
                     /locus_tag="LP493_001900"
     CDS             complement(20967..23594)
                     /locus_tag="LP493_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134047.1"
                     /translation="MKAIKEKIVSRKINWLALSVLVLMISVVFTSNIVEASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSVINTIVVGLMILSLMFVGYKMITGKGTIDLRSVGMNIVMSVALI
                     LLMPTMISSGIQFAKIFYNDATTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNKLTRKNFQQTDLTQVLTDKVIDKLEKENPAADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNAGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSTGFNRAKGSGN
                     GNGSDSGEGEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERAIK
                     PFKSMRDMANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSMPTRLSDR
                     KDGAKVENADRIMSSSERMREAMKNNAESNNNPVSAIQQKVQQDIEERKNAMHGQAKS
                     AEELINQKRQEAKYTPEAMNREEMLRKRVEGRTGANTDEKEALTKERIQEAKNSNTGL
                     EKLVKENLQNSTSSQGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNGQGTKTIDV
                     RENVQNSTSSQGFKSMDVRENVQNSTSSQGFKSMDVRENVQSSTSSQGFKTVDVRENV
                     QKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKPRRRFTYEDNE
                     LFRDTLNDPNPLFDNLLKK"
     gene            complement(23581..23799)
                     /locus_tag="LP493_001901"
     CDS             complement(23581..23799)
                     /locus_tag="LP493_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134048.1"
                     /translation="MIKNRLIDQMWCLDQNTDTLELIESICFNTVVLDLRAENDNCVT
                     HIIINQKMAQQLSESLRKWAEGENYESN"
     gene            complement(23796..24671)
                     /locus_tag="LP493_001902"
     CDS             complement(23796..24671)
                     /locus_tag="LP493_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134049.1"
                     /translation="MNAIVILAEITYWYRPKKIFNDDGQLLGYQKKFLEDILQKSYKQ
                     LSKKTGLSERAIKDAIVYLEKKGIIKRVFRNIYYEKRAVTLSNVMYIVLNVHKLIEIT
                     FPTLDCEKKEYMPKIRQRGIEKKRYVSLKKGRGMYKFVYTYTKTTSQNISKTTLVMEE
                     EDINIKRIYSKISVLYDANNEDGRKLFQVYHYLRNANVDTEDIRKIIEYLSENTQYLI
                     AECIIKQHEACFFQRKTEEGLYDYVTYFLNGLQKRYKSQFLENVEPIDQFKKAFEIKE
                     LPEITMHNWLKGEES"
     gene            complement(24936..25235)
                     /locus_tag="LP493_001903"
     CDS             complement(24936..25235)
                     /locus_tag="LP493_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2134050.1"
                     /translation="MEAIKLMISEEQEEMFLKQFYQIATKAIEKAQENAGMTREYLNQ
                     KEMAEYLNVSENFLKNAVRNEGLPVVELGARKFYSKKAVNEFMFARMKRGENIGR"
     gene            25437..26234
                     /locus_tag="LP493_001904"
     CDS             25437..26234
                     /locus_tag="LP493_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2134051.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNSTIDWIKWGTLEEYITSYLIDIGYELYIKDFPEIPHKVFKD
                     IQERYSDTFSLDKDYELLNPIIKNIFTKYYSKDFEIYLNEILANNINPLIEEYANQRH
                     SISKELFFKRANSKLQDKIRNGDFKYGEKERMIDSLKQLLDEMDLAYKDISKYSSVED
                     FFYKITKNQFETEKFISDLSKKYNFPYEKNSIIAKFLTDNHDKFKNN"
     gene            26285..27427
                     /locus_tag="LP493_001905"
     CDS             26285..27427
                     /locus_tag="LP493_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL2134052.1"
                     /translation="MATFFSYKLQNGEKYWGFETYLGKDPKTGKDIRTKRRRFKSKAE
                     AQTALNRLLVDFKEKQEFKINVTTFQELYELWIDNYRTRVKPSSVAVAQRFCKNHILP
                     AFGELRLDKISVSYCQKQVNEWHKTLKQYGFLRKTTAQIFKFGVAMEVCKDNPMSKTL
                     LPRKIEEEQPLKFYTKDQLQLFLQNTKENNSVKLYTFFRLLAYTGMRKSEALALQWED
                     IDYFNKTITIGKTIAQDEFNQVVLQVPKTKNSSRTIQLDDFTLKQLRIWQQEQMKIMI
                     LYGYNTNSPKQFLFTTNTNKLYYLQVVNDWLDWIYKKTPMEPQITPHGFRHTHCSLLF
                     ESGASIKEVQERLGHKDIKTTMNIYAHVTPQSVKKTGDRFAKFMGE"
BASE COUNT         8667 a         5154 c         3887 g         9789 t
ORIGIN      
        1 actaatacag gtagtcctct tttttgttat tttgatattc taaatcattt tttattggat
       61 tattcccttg ttcgatatag acccaaattg atctatcaat aattatcaaa ctgagtcata
      121 tagagacaaa aatttcaaaa atgacctgtt aaatggtcat cgaatatcat ttaaaatcaa
      181 tacgacggag tcagacacgg agtcaaaaca agcccgctga gagtaaaaaa tatatacagt
      241 cccataggta aagtgccaca ggactgtata tttttttatt tgagattacc tgaaatgatt
      301 ccatttactt tttatctcat tttttcctac tagttagtat caaatactct cctattttct
      361 caataaacta ttttgggtta catggtatct gaaacagcta aaaccttgtc attacagcaa
      421 aaaatcactt tatctccgtt tcatttcaga tacatttcac ttaagcggat tccaaaaaaa
      481 caaaagaaaa aggaacccct agttagccta tgctttttat tggttcctct caaaacacgg
      541 tcatataaca acggggtggg gtaaatgaat gaaaaaggtg gaggaaacat tattcaatag
      601 ctgtcttaaa tacttcgtta taaaatgtga acaaataaaa gacatctatc cctattttct
      661 acacttccac tttactacca tctttgaatc gtacaatttt cttaactctt ctcgtttacc
      721 tcaattcatt ttcaagtgga atcagctcat catctaacat tttacgccat gctcgcttca
      781 tttcttgtgg gtatttaaat ggcttcgctt ctggatggtt ggctttatat ccttcgtaat
      841 ccttactgtt gataattgct ttcatattag gaattggatc ttcacctggc atatattgca
      901 gattagaagc atgtaattct ttctcagaaa caaaccactc attggaaaag acatgaatca
      961 aatcatcact cgcttgtgta aaatagcgac gtttaatgac aaagatatct tcattactat
     1021 ctaaagtccc cacatcaaac gcatttaaaa tttgtcggta aacttctttg actccttctg
     1081 ttttattcaa tttagccaaa gctttttcaa tttcttctcg tgcatctgaa ctattcgccg
     1141 cataagttcc tagtaattga tcaatataag tagaatcaat atcatacaac ttcgtggtat
     1201 tttcactata aaattcgatc gtggaaaaat cttctccctc tttttctggt tcttcctcta
     1261 ttaatgaacc cttcacggtc tcgtacacgc caatttgttc ttccaaaagt tgaatttgat
     1321 tgttcaaggt tgaagatttc accatgtcat cattgtaatc gtcataagtc actaacgatt
     1381 cataagcacg attcaattct tggaatgctt tgacgtactc gatacggatt tcaagtggcg
     1441 tatgttcatc aatggattcc atggatgaaa cctcttttaa cttaccatat gcttgcttga
     1501 atcttttttt ggattcctga taacttggat aaatcaaacc cgattcttct tttgcttctg
     1561 aatacagttt tgtcgcatcc tcgacattct tctccattgt ggctggcttt cggaaagtaa
     1621 caattagtcc ttttgttttt tctggatacg tacggttcgt acgtgaaaaa gcttggatca
     1681 atcctgcata ctctagatta cgatccacaa atagggtttg aatcgtaggt gcgtcaaaac
     1741 ctgtcaatag acgatccact acgatcacta aatcaatttg tttcccaaat tgtttgaatt
     1801 ccgctctttt tcgtgccaaa cgattattga tgtctccgtt ataacgctca atgtctgcta
     1861 atgaccagga agtatcataa tactgattat attcctcaat aattttttgc atttcttctt
     1921 gttggacact tgaatctcgg ctgttttctt ctaatgaata ggtaatagcg attcgtggaa
     1981 aatcaggatc ctccatcgtt cttccttcac gaatgggctg attaggaaac tcttttgtta
     2041 accagtcagg ttctttcgtc atttctttga tcgctcgata atactttttg gccatgtcaa
     2101 tggaactcgt ggttaagatc gcagacttcg ttggacggcc atttcgaaaa tcaaattttg
     2161 tataggcatt gtctggacgg aacattttat gaatgacttt ttggatatgt tcatctgctt
     2221 caaaaacagt agggtccaaa taactttctt ttttgacagg ctccatttga tcaatcatac
     2281 gattgatctg ttccggtgaa tactctgcat atgtttctac ttcttttaat ttccgataga
     2341 ttttattctc taatgaagtc ggctccacgg tgttttcatg ctctacttga aatcctaaaa
     2401 ccgagccatc ttctaatgca ttcttgatgg tataggtatg caagacctct ccatactgat
     2461 catgggtcgt acgtgccaat tgccctttgg cttgtttccg attctcaggg aaaatcggtg
     2521 tacctgtaaa gccaaaccaa gtggatttcg gaaacatttt tttgatttct tccatatttt
     2581 cagcacttaa cgctcgatga cactcatcta ctacaaacac gatatgttgc cccattaatt
     2641 tttggaagcg attggttcct tttttctctt cttgtttttt tgcatatttc aacgccgcat
     2701 ctagcttttg acgggttgta ataatcacaa catttgcatt ggcatctgcc aacagagttt
     2761 cacttaactc tttggcactt cctgttccca cgatcaagct attcgctttg gcgttcccgg
     2821 aagaaatccc agtattaaat tccgaagcaa atttcgtaaa ctctgtggtg gtttgattat
     2881 ctaaatcttt gcggtccact aacatgatcg tccgatcgat ccccgatttt cgtgctaaaa
     2941 gcttagtaga tacaaaacta gtcaacgttt ttcctgaacc agtcgcatgc cacacatatc
     3001 ctgattgatg tttatttgca gcaataaaca aggcttgaat cgcatgtact tgataaggat
     3061 gtaacaccat gaggatttta ttgtcttgat cttcactgac aatcgtataa tccgcaatca
     3121 agcgatgagc atccgggata tttagcactt gtttgcaaaa ctcatataag ttttctacct
     3181 ttttattatc tttcgttcgc caactaaata aaaacttagg atgcaaatcc tttggtaagg
     3241 catttgcaaa ataccgagtg gtttgttcat tggaaaccac aaacaactgt aaggtcgaaa
     3301 agatattgtt ccgaaacata ccttcttctg catatttttt gatttggtta aacgcctgat
     3361 aaaaactatc ttttgcggtt acttgtttca gctcgatttg gacaatcggt aatccattga
     3421 tcagtaaggt gacgtcaaaa cgtcgatccc gtgcttctat gttacttcca cgttttgcaa
     3481 tttgatggac cacttcatag gtagagattc ctccaccaat gtcttgatta gaataaagaa
     3541 tgagcgagac agaacccagt tgcggatctt cccgttcaat cgtgatccga gccattccat
     3601 tttcaccttt taaccatttc gcagcatcaa agggggtttt cgttcgtagt aacaattctg
     3661 ttttgatcgt ttcaaattct ttatcggtca aaggaaaatc attcagttct gcttgattat
     3721 ttgagatgat tttttggcgt aaattgaccc aaagatcttc ttctgatttt agatcgggac
     3781 gatacgtcca ctgattatgc ccttccccca atacacggat caactgttct tcgacttccg
     3841 cttcctcacg gtgactaatt ttcatttatc ttccctccct aaacaaacat cttttgtaag
     3901 aagccttttt tcgtttcctt cagcaaatct aacttacgtt gatgaagagc gatcgtgtcg
     3961 tcgagttgtt tgaagaaagc gccgattttt tgttgttcct ctttattcct agtaaaagga
     4021 aacttgatat tagcgaaatt ctcatagaat aagtattctc gtacgcttcc ttcagtgttg
     4081 cgcttgacct ctttgataaa tgttggtgac ttgataaact gaagtatgaa ctcattatct
     4141 aagtcctcgc tcattttcac aactacataa agagagctaa caatgaccgt cataccaaga
     4201 ttgttaaatg caattgatcc tacgtttact cttgctggat tataggcgaa ttcatttggt
     4261 tcaacgaatt tataatttgt tttttctaaa tcatccaacc tactaccatc aaactgttct
     4321 gtttgagaaa ttaaacctgc tttattactt accgaatagg cagggaagtc taaatctttc
     4381 gtgttctttt ttccagtctt cttactaaac tctttgaact tacgctgttc ccaatcttcc
     4441 gtaaatccag gaaaccgaat ttctggcact tttgctccgt ttttagggaa cattttttgt
     4501 aagaatcctt ttttcgtttc ctttaataaa tctagcttac gttgttgaag agcgatagtg
     4561 tcgtccagtt gtttgaagaa gttcccaatt ttcttttgtt cttctaatat tggaaattgt
     4621 actatccatt ttttcacttc tgacattggt acgagatttg taattgctga acctggatta
     4681 gctcctgtga gttttctttg cataaaatct gcacgaataa attgaataaa atattctgaa
     4741 tctgtgattt ctttatttat tctaagtcta atcaaagcct gattgaatac acccggtttt
     4801 atttgctttg gtactcttga aattctccca attgttccag cgccactcat gataaaatcg
     4861 cctggttcta atttaaattt gattaattca ttatattttt tttcagtaat tttatatctt
     4921 gtttcgtaat tatcataaat agcattttgt tgttcataga caacaaaatt gctattagat
     4981 acaaagaatt ctttctttaa ggcactccca aatggtcccc tccttactcc atctttttta
     5041 tcaagtaagc attcaaactt acgctgttcc caagcttccg taaatcctgg gaaacgaatt
     5101 tctggttgta tatcattact catgtttgaa cacctccagc gcaccttgta accacgcttc
     5161 attttcaggt gttgtttgca gggaagagat agcttctaaa agttcttttt ctagcacttg
     5221 ctgttcttgt cgtatcttct tgatgtcatt tccgacatga accatatcaa ttggttcttc
     5281 ttcttcaaac gtatctacat agcgtggaat atttaagtta tagtcatttt ctttgatttc
     5341 atcaaagttt gccaaatgag cgtatttctc gacatctttt ctttcagcat aggtttcgag
     5401 gattttttga atgttttctt ccgataattt attctgattt tttcctttga caaattctcg
     5461 actagcgtca atgaataata cgtctcgagt ttggcggttc tttttcaata caatcaccgt
     5521 cgttggaatc gatgtcccga agaacaagtt cgcaggcata ccgatcacag cataaatact
     5581 gccgtcttct agtaattttt gacgaatgac cccttctgca gcgccacgga ataaaactcc
     5641 gtgtggcaag acgatggcca tagtccctgt ttccttcaaa tgatagaaac catgaagaag
     5701 aaacgcaaaa tctgctttgg attttggcgc taattttcca taacgattaa accgagaatc
     5761 gtctaagaag gtcgtatctg ctgaccaatt agccgaataa ggtgggttca ttactactgc
     5821 atcaaatgtg taaggttcat ctgttggcca atccttattc aacgtatccc cattgcggag
     5881 attcatttct tcggcatcta ccccatgtaa aatcaagttc atttttgcta gattgtatgt
     5941 cgttgtattt aattcttgcc catgatattt aacgttatct gggtgagtta agtagttacg
     6001 cacatttaac atcaatgaac ctgaacccat ggttggatca aaaacactaa agaatcgtcg
     6061 ttctttttga tccaacgtca cgatttgtgc catcatatca gaaaccatat gaggcgtgta
     6121 aaattctccg gctttcttcc ctgcttctga agcaaattga ctgatcagaa attcataagc
     6181 atccccgatc acgtccccat cgtgacctaa aacttccacg tcattcaatt tcttaatgac
     6241 ttcggtaatc gtcacatttc gttgttgctc atctgttcct agtttttttg attggagatc
     6301 cacatcatca aataacccat taaattgatt gtaggtagat gccaattgca caaaggcttt
     6361 gtttagatca ttcaattgga acgttgcttg ttttgcttga tccgctaaga cgttgaaaag
     6421 atactctggc gaaatcgcat accccaaaat atcaacgatt gttgcaatca gatcttcttt
     6481 tgattcttca tctgaaagta attcgcgata caacatcgtt tgtttgctta ccgtatcata
     6541 ttcctctaag gattcatctg ctaaaagaac cacttgttcc aacaaacggt cggataaata
     6601 tttatagaaa atcagtccca ataaataatt tttatattct gacgcatcca ttttgctacg
     6661 gagattatct gccgcactaa ataatttttg atttaattct gcacccaaaa agatacactc
     6721 ctatctctta tttaaagttg ctatataccc tcttatttta gcatactccc ttttagaaaa
     6781 agcaaaaaaa aaaagaaaga aacttattct tgctaataaa ctacgcgaaa ggagtctaac
     6841 gttgtttgat ataacttaga ctgatcgtta acttattttt tatatttcta catagttatc
     6901 tttagaacca tttcagatac atatgaaaca attacatatg attttttcat aaaaaaacag
     6961 tactgtctag tagtataaaa tatacaaatt tcttaaaaat tttttcacta aaatcactac
     7021 ctgaaacagt ctaaaacact tatatatcaa cgtttaatga aactatctcc gtttcatttc
     7081 agatacaaat aaatatagtc gggctccaaa tccgaaaaaa aataccccca gtagcttatc
     7141 ctaagctact ggagatgtat aagtacggtc atataacaac ggggtagggt aaataaatga
     7201 aaaagatgga agaatcatta ttcaataact tttttaaata cttcgttgta atcagttacc
     7261 tgtccgttct taaataccac agaataatct tttttcccat tttcaagtaa ccgaagtgga
     7321 atatctttac caactttctc tgtcactgca ttactgatac ctgttagatt agctaataaa
     7381 tctgataaag attgagcatc tgtagaaatc tctgtatcag tatttatcgt gattccttta
     7441 tcttcattta caagtttcca agtaggtggt atagctgtgt atgtttctac aaatgaatta
     7501 agtttttcat taagtgactt ctcttttata tttccatcta aaaactctgt atatatggct
     7561 tgagctatac taaaacaaag ctggccttgt tctaataatt ttacatcatt agttagtaaa
     7621 gctgtgttca cgttatcaat cgcttcaaga agagtatctt tggtgtccct aacagcttta
     7681 ggtgtgcctt ctggaatttc cctacttgat acctcgtcca ttttatcttc cataaacccc
     7741 ttaaaatcat atctttctcc caaatccata gaagtttttg agaaagcttt catttctgag
     7801 tctatttctt caataatatt taacatgtct gatacatatt gtttaggctg attcgttttt
     7861 aatctatatg tggtaaatat ctcaattcct ccaattatca ataaaattgc caaacaaatc
     7921 cataataatt ttttcttttt catttttcct cctatacact gctgttataa cagtgactaa
     7981 tgtaaagatt ttcccagcaa tcatcagact attatttaca gggaatcaaa aaaactcctt
     8041 agtaagctta cacctttagg agttcctgtt tgaacggtat gcataataca tttaaatcaa
     8101 tttaacatta acacctcagt atatggtatc tctacatata cacggtcttt ttttggatag
     8161 tactcgacat ttatattgat agcacttcca ttgtctaacg tagctttagc ccggtacgtg
     8221 ttatcaccat tatcatgagt gatcgtcaca tcatcacatg tccgatttaa gttatactgt
     8281 tcttgtaaaa tctgagttac caatggtaca gatgacttct ctagtccaga tgaacccgtc
     8341 attcttgaaa aaattatacc tataatagcc aatacaacga tacctataat gacaaacttc
     8401 ttattcatat ttactttatt caacttttta tctcctatct ccaaaatgat tttctctcat
     8461 cagtaactca ttgacatccc caatagtaca ccaaagatgg ctccagctac ccctgctatc
     8521 atcaaaatcg tacccatttg ttcatctttc tctcgatata agtaacccat aataacagca
     8581 acagcaccaa ataccacagg aataaatgct aatgatacta ccatagaaat ccaaccaata
     8641 atcaaataca gcttccctgt ctcttgtcca tgtacgattt gttccttcat ttcattaatt
     8701 gtctgctcag tacttttctt tactgtgtct gttccggttg tctcatctgt ttcttgtaat
     8761 gctccgcaaa actggcaata cttactttca tttgttattt ctttaccaca ttttctacaa
     8821 tacatgtctt ctcctcctaa aatcattcaa ttgcttatta gctaactgtt tactttatta
     8881 aatacatcag aaaacagctc atttattggt acacttaata tctcagaaag cattttcatt
     8941 tgatagggtt taggaatcgt tctccctgtt tgccacgaac ttacacattg ctgtgtaaca
     9001 ttcatttttt tggctaactc agtttgggaa agtccttttt cttttctgta tcggctgaga
     9061 ttacttactt ttttcatgat tctcccctcc tgttttatta tatacaacaa tatgatgtat
     9121 ttcaactcat aaaatatata aatacttcaa atgtcattac aaatacaaca acttgttgta
     9181 ctctactgag aaggggggtg tattaatgaa acagaagcaa tatgcaaagg tcattagaga
     9241 aaagcgaaaa gcactcgggt ggacacaaaa agaattagct aaaaaaatct tctctacaca
     9301 acaggcagta gcaagatggg aaaattctgt aacagaacct aacctcgata gcttaacagc
     9361 tctttctaga gccctaggaa cccctgtaag ccattttcta gacaatgttg acatagatta
     9421 tgaggaagag tttttggctc tctatcgctc tcttagtact gaagatgcaa ttcgaacaat
     9481 tgactatatg aagctattaa aaaggcaaga aaatgaacgc aatcagctat tgaaagattg
     9541 aaaaataaat aacccaccga actttaacgg tgggtgtatt gagatgaaat aagattaaga
     9601 gctatggata acctgtctag tttaatataa ttgggtctct tctattcctt actctccgtc
     9661 catcatctct tgttacactt gtaaattgat aaataggaac taattcaact cctgataata
     9721 tcaattcttt tattacttca tctatccctg cccctttcgc tagatatact aaaaaactac
     9781 tgcttgcttt cacattgtat agtttcttaa tatccttaga agctcgttca agagtgaatc
     9841 cttgtttaac aaagtagcct ctgttttcta ttaaagcatt tttcacgctg ttatccctga
     9901 catttcgtag gcgttcacaa acagtgttaa taagttcttt ttctgtcatt agatatgtcc
     9961 cttgccacga taagccctgt aaaacttcat gtgcttcatc taaaatcaat tgtttttcct
    10021 tgctaagttc tgatcgggaa ttttgaggaa atactctttt agcctctttt tcgttaaaac
    10081 atatcttaac ccattcataa gaaaaatatt gatatgtaaa atgaaatttt tccagaagtg
    10141 gaaggatatc ttcattcaat ttttgaatca cagaagttgc attaaaaacg tctaatcgat
    10201 agacattgct tctcttatgt ttaaagtttc ctaacgcttt ctcttccttt aacctattta
    10261 ggtattcgag catcttcaaa ggaacatctt catcatctaa tttttttatc aatcctataa
    10321 aagtcataag tgatagtaac ttattacatt tatctatgtc ataagtttta ccatagtaag
    10381 aactcatttt tttagctaat tgttcccccg acaaaataca agtcacactt tccttactat
    10441 catcaaaaaa attaacatca gaaagcaaga catcatagac acgtcgcatt tcctctagat
    10501 aattccttat tgtcctgaaa agtttgtctt tcattgattc aagagtgtca aaaagtactt
    10561 ttgattcctc tttcaatttt cgaaaatgtg taggatacaa gtctaggttc tctaatagcc
    10621 aattaaatgt ttctacccga ctgtctttct ttaaaattag catcacaact ccaataaaat
    10681 tttcactgat atcacaatta ctggaatgac aataaaaaat ggaatgccca gttttactgg
    10741 taaaaatact agcagaggga ttatgatcgt tgtgaaacag acatcttaag tttttacttg
    10801 acttaagtaa tttattcata tcaatggtta acaatctttc ataaatctca ttaaaagaca
    10861 tgtcggagga atcaaacagg cagtctttaa accactgttt catttcttct ttgtcgtcat
    10921 tttttatcaa cttaacaaaa tcggtttcat tgactagttc atactctctc cctgaatcac
    10981 tttgacaatt tttagaacat gtcatggtaa aatcaatcgg aagctcagta atatctaaca
    11041 tgttgtcttc attaattatt atcactgcat ctgacttata tcctccaaaa aacattctat
    11101 tcgaagcatt tacattgtca tcacacccgg ggatgttctt tttcaagtat tcgtaaacag
    11161 caaccatttt accatagtca gtaattgctt cttttaatag aaagacaatc ttgtattttt
    11221 ctagattttc agagtaccga atactttttt gtatcgcaaa cgcagaatta tgaactaaat
    11281 tgatagataa aaccttttct atgcttaagt atctactatc atctttactc aaatctacta
    11341 ccttcccctt ctcatcttta acagtgttat cgacatccag aataattact ctggtttcca
    11401 caaaactctc cttgtcattg cctttattct ttgtcttgct tggaataaat gattgtgatg
    11461 aatttagtat ctctacaaac tcatctcttg taacttctct atagttatct aaacacctat
    11521 ctcttacatc agttttttct ttttttgtaa ctggcttctc taataatttt tctttatcta
    11581 cataaattgg aatattaatc attgatgttt ccatttgtgt ttcctcctta taaaattctg
    11641 ttaaagacta aaacatacag ataataaaaa caaactcttt attactatat gttttagtct
    11701 tatttgttta ctcaaccttt ataccgttcc atgaaactat caatatcaga ttttttaaat
    11761 ctaatgaccg tatcaatttt tataacaggt aacccgtatt gagaaacata ttttctaatc
    11821 gttcctactg atacacctag atattcactt gcctgctgat agtccatata ctctagagtg
    11881 actccagaaa taatgtcttc tagcataggc tttagcactg taattatctc tttcacttgt
    11941 tgttcaactt gtatagaaac aatgctatca atgatttgta gagacatatt tccccctcct
    12001 ttcgtgattg cttgaacaaa ttttctaaga attatcttcg tattttttgc tcaaaataaa
    12061 agtattttgt tattaaccga ttaatcaaac aaaaaatgat taccagttca tcgacataca
    12121 cataatacct cgataaaaaa ggggtgtcaa tagttttgta aaatttattt acaacacccc
    12181 ttttttgagg tatactaatt ttaggaggtg tggtcaatat gataaaacgt ccaccaataa
    12241 attatttaga acgaaaaaag atactcggaa caaaaataaa agctataaga aagagtaaaa
    12301 aattaacaca accagcattt ggtcttatga ttaacaacgg tcaattaatt gacaaaaaga
    12361 ctatctacga atgggagaag ggaacctatt taccaatacc agagcgatta tcccgaattg
    12421 ctgatttggg aaatatgagt atagaggagt tagtttgtgg caatgtagaa gaatatattt
    12481 tgggaattat tctttataga gatagcattg tactagatgg tataacattt ccagataaaa
    12541 acctgttcca gcatcttcgt caacagttcc caccagtaca ctctaattta gatacatggc
    12601 tggatagata ttccaaatta gaaccagaga tgcaagaatt tattgctaac aagacttgta
    12661 ataaagttaa aaatgaaaaa attagtcttt tcaatatctt aaaaatagaa gaattattca
    12721 tcaatgctat tgtagaagaa tttgacaata acattctttt cctcactagc agtatagaag
    12781 aactactaga aagaatggta gatgaatggc tacctattca attgaaagac atgtcttatc
    12841 ccgaagaagc tgtgagagaa attactgata atataaacaa gctagaacaa acgatttcat
    12901 caattgggaa aaaatacact aagaaaaaaa tgaagggagg tgataccatc tagtggtaag
    12961 tactccttgt aaactaagag gagatgattt catggcaaaa atatcaaagt acaaaaagaa
    13021 aaacggtcaa gtggcgtgga tgtataaagg acacattgcc accgatccac gaactggtga
    13081 aaaaataaat actacgagaa gaggttttag tagcaaacaa gaagctcaaa aagattatga
    13141 cgagtacaga catcaaatat tatacggtgt taaaaagaaa gcacctgata tgacatttga
    13201 agacctgtat aatgaatgga taactcatca gcgtaccagt gttaaagctt caacaatcgc
    13261 aatctcagta agatacgcaa ataatcaaat acttccagca tttggtaagc ttaaactatc
    13321 gaatatctct gtcccatatt gtcaaaaagt ggtagatgaa tggcacagta aatatgaaag
    13381 ttacgattat atgagaaaac agactgcaca aattttacgc tacggggttg caatgcaata
    13441 tattgacaat aatcctatgg aaaaaacact tcttccacga aaaaaagagt atgagaaaaa
    13501 tcgtaaattt tactcaaaag aggagcttaa taatttactg gatgctttta aagattttgg
    13561 taacatgaaa caatacgcct tcttcagatt attggcatac acaggtatga gaaagagtga
    13621 agtactcgct ttacagtgga aagacataga cacgtttaat aaagaactac atgtcaataa
    13681 aactcttgct gtagatgaat ttggtaaagt tataattcaa tctccgaaaa caagagcttc
    13741 tagacgagtt atctctttag atactgagac tctttctatc ctcaacaact ggaaattaca
    13801 gcaaaaagaa gagtatttaa aacttggata caatactagc tctaaagagc aacatgtttt
    13861 tacaacagtt aaaaacactc tatacattcc aaacactgtt aatgattggt taagatatat
    13921 tttgaaaaaa tataacttgc ctcgtattac acctcatggg tttagacata cacatgctag
    13981 tttattatta gaagcaggag aatctgtcaa ggtagttcaa caacgattag ggcatgaaaa
    14041 tagtaaagtg acattagaca tctatgcaca tattacaaat aatgcaccta agaaaacagg
    14101 tcaagacttt gctgatatga tggctcatca gtaaaagagc tggtcaaaat ctggtcattt
    14161 ctagtataca ggcaaaacaa aaaagctaga acccttatat atcaagggtt ctagctccta
    14221 taacaggttt acccaacact gccttccaat gactcttttg ggaatcagag gaaagaatca
    14281 ggctttatag agatatttca tctaacaaat tactttagac tgacagtata tatcagcagg
    14341 tactgtcatc gggaacgtag ccaatatcgt atccaaaaca gcaggtagag aagctatttg
    14401 aggattcaag ttattctatt tcaaccatga agttaagttc attaaaaata aagatagttg
    14461 gtatttcaat aatttttgta tagagttaat cactttattg atgctaattc atcttgattg
    14521 gtattataat cgtattcaag ttgcgtggcg tgcttttgct agaaaatata taactgttct
    14581 ttataaagaa atataaggat taaacatttt ttatcataga gttttactta tctatagaat
    14641 tatgtctgtt cctaattcag tttgatgaat taactgataa aaaaatatct actatttaaa
    14701 gatacaggga taagtaagta aaaaaataac atgtcattag atagtagaca gttccaactc
    14761 tttatttacc ttttttgtat gctgcactgt caatccaagt tcctaaattg ttgtatccat
    14821 catcacttat ataatcatat tggccatcaa taatttcgtc aaaccacaaa tattctccat
    14881 ctggtttttg cccaattatt ttaattactg attgactagt agttgtcatc tggttaaaat
    14941 cttttatttt acctatatta acggccaaaa tagcatttcc tcgcttataa ctctcctgga
    15001 tttcatattt aacatattct cgatcaagag tttctttacc tatcagcacc acagtcactg
    15061 atgttccaat taattgatta tctatccagt tttttatagc aatatctcca ttacgtttaa
    15121 ctttctcaaa ttcagcctta tctacaaaac cagcttcctt tgttcctcgc aaagtccagc
    15181 tgtttctaac taccattgct cttgttacat ctgcataatg gaaactaaaa aaaacccttc
    15241 tcaccatatt aatcctcctg aatactattt attaaactga caatttgttc aactttttta
    15301 tctacttctc cttcagtatc taatttttct agcgcttgaa atttactttt taaggaatca
    15361 tcaaaataat cactgaaatt ctcttgaatc ttatcaaaca aaaccttact tgcacctttg
    15421 gtaaatccaa tcggaactac tatattttca ttttgaacag ataattcaaa ttcttcaatc
    15481 attccatctg ctgtaactat ttcacctgat tcaagtttgt ttccaaaaac aaaaatacta
    15541 atcccagact ctgcaataat gttttctcga tatcttctcc actcatgagg catatcaagg
    15601 ggaagtggtc ttaaagaaag tacgtcttgt atgttatttt ttcttaaatt tcttctctgc
    15661 tttagaactc ctgaaacaat actattacca attccaagtc cgtaacctga tactattcta
    15721 taaccggatt cagaaagcct atatgctaat ttctcgacaa attttaatcc tttcgattca
    15781 gatgtaaatg gagtataatc aacagcactt cccgaaataa aaatagtttt tctcaaatac
    15841 ttttttctaa tacttttcaa aatatcagta atctcagaat aatcatctac ttcaacaacg
    15901 tttatcgaaa atctggacaa atcattgatt tgtagtcttc tttttgtcag ttcataatta
    15961 tatctctctt gatcaaaaaa atcctcagaa tcgacaaaat tttcctttaa tatttttctc
    16021 attatacaat aatgaggtct ttggttttct ctcaaaaccc atcttatatc tgataaaatt
    16081 ctttctaaat tagggtctgt aaaactaaat cctaaaaaga gaaaagtttt tgttaacaaa
    16141 tctcctttta aagtttcttt aaataacgcg tacgaatcat catcatattt ttcataatca
    16201 tctcttgtta ttactgtcga actgacatca tctatatcac catgcatttt ataaacaatt
    16261 gtatccacat ttggattagt tgttgctaac tgagtataat ttttcttaac ctgagggttt
    16321 ttataagctt ctcggattga tttttctatt agatgatcat aattagttgt ccaataagtt
    16381 tcaataggta aacttgctag tattcgatga ttttcagata tttctaattc ttcaccaaaa
    16441 ttatccataa gtatctgatt caaaattcct cttgatccac cattttcatt tttataatat
    16501 tgagccagag taactaagtc tgtttctttt ttagaatcca acccgatttc tgttgcagga
    16561 tcattaagta gttccggcca acttacatat ccttgtgaca tcgataatcc tgcacctgca
    16621 aatattgctg catttccttt ttcaatagct tcagagaacc tctttattaa aactttctta
    16681 tccattctac ccggttcctt tcgattcagt aaattgatta gagattagtg aaaatggtgt
    16741 ttttatataa aatatctaat gtattacttc ctttagtgca ttccacagca tctaaagccc
    16801 attttttcaa atcagctttt cgtaaataag ttaattcact taaatttaaa gaatatttta
    16861 tttgcagatt ttcttgcgaa gaatagtgct ttataatgct tctaacatcc tcggtgctca
    16921 tttgaggatt actttccaat cgtggattct ttttttccac tattgaagct gtcgtcagtt
    16981 cgctatatag ccatggcgaa tacgtaaatt tctgttcatt agtgatttca ttgctcaaac
    17041 taattgaatt aggtgtatta agaaaaaaca gacattctgt actatcaatc atattattta
    17101 aagctgtaga aagcatcata tgaacatgac tagttgttac atttctttta tcataatcat
    17161 atgtttttgt ttgttcctta tagcaatatt tttggtctat tttttttaat aaatcagaac
    17221 tgtatcccca aaccgaagaa tcaataaatg cagtaagacc aaaattttca aatagccatg
    17281 atgcaaaacg tatagctaat ttttcatcag catgagagtg agatataaaa atatctgctt
    17341 ttatagttgg aaaccaatct ttaataattt cgtctgcatc tagaattttg ctgtccttag
    17401 aataataatc aactaaatca ttttcacttt caaatagatt ttctattctc ttgttaatag
    17461 atttttggtt gtgatctatt tgatttacta catgtgtata tgattgcgag cttgaggaga
    17521 atgcatttaa gtcagcattt gtaaaatcca attcatatgc cttatacaag gatatccctc
    17581 cattcttgta ttttgatcca caatttatta ggcaacataa cagtataccc tatcgttaca
    17641 tatcccattc attattatac cagtatttct tcgtgacaca taagggtgta acataataat
    17701 ttcaaacgaa atgactacaa gtagtcattg aagcaaatct tcataagaca cctgtagaat
    17761 atctttgatg gctttcaatt gatccaactt aatgtgttgg cggccacctt caatcttaac
    17821 caacgtttcc ctagttatag caattttacg aagctgtagg tctctaatca gctcggtttg
    17881 accaattcct ttttctaatc ggactcgtct aatattgcta ccgattacat tttctttatc
    17941 aataattttt tcctctttca agaatagcac accttttgga ctaaaattag tcctttttct
    18001 tattaatctt aaagattcgg tatgctacaa tgggactagt attagtccat attcaatttt
    18061 aaggaggaat ttttttgaag aaatttgcaa tcattctaac ttgcgcttta ctcatcggaa
    18121 ctataagcgg gtgtaccact tctgacacaa gttctacaag tacggaaact agtacaacaa
    18181 cctcagaaaa gaattaccca atacattttt ttccggttcc agatggattt gaagcttatt
    18241 atcatgataa aaaactagat gttcctttat cagaaactga atctactgaa aagattttgc
    18301 caattgaaat tgaaagaaat caagacgata taaaactaaa agctgatctt cccttactga
    18361 acagcacaca aattgataga catgaaaata ttaaagttaa tattgaaaaa ggagcgttag
    18421 cacaacttta tactgaaaaa gttgaacaat tttttgaggc tggtgccaat aaagactttt
    18481 caaaaataag cgattattcg gataactttt ttaatgagac ccaagatgaa atcacgaact
    18541 caacttttat ggctgaagat atgtacaata tgaagttgaa aaaaataaag tcgtatgatt
    18601 atccattaaa tctaacatta aataaaggga tactctcttt tgtattagca ggttacgttg
    18661 actatgaata tacagcagat tatttggaga cgccccttca acacgataat aacgatatta
    18721 attttagatt tatctacaat tcaaaaagta aaacatggtt agttgatcaa ttgagcacta
    18781 taaatacggg atttcatgaa ttacctaagc ctgacaatga aactgctttg gtcattaaaa
    18841 cattctaaaa aagaaacgtt gaaggaataa ttattctttc aacgtttctt ttattgtttt
    18901 tcagtttacg gtcttacctg agcgaataat ctgatttcta aatgattgga aaacttcttg
    18961 tggttgataa taatctgtat ctatttcaaa tgtttctgag aataattcat tgaatttttc
    19021 tactgaaatg atgattttac cattctcctc tcgactgttt tctattattt ctgcctctaa
    19081 ttcaaataaa tctagtgacg aactaaaatc ataaatcctg tcatattgaa caaaaaaatc
    19141 aagaaaaagt tgctcaaact cttccttatt tatcactagt gtttcaagcg gaacaacttt
    19201 attttcatca gccattcttc caatttcctc actttcattt tcaattgtcc attgttgcgg
    19261 acgtatcaga ttttctctat catttttcag tgtatagatc acttgtaata cacaacaatg
    19321 ctttgtaaac ttattttttt agttagtcga atctttttaa atgtgcgttt cataccatgc
    19381 gcttgatata ttttctccta ttttttaaat cgtttatcac aacttttatc gttttttctt
    19441 ctgaaaaaaa tcttgtttac atcgttacat agtttccaaa aagatacatt actagtagaa
    19501 acaacaagat taattttact tcccactgaa atgggaagta tattttaaat attttttctc
    19561 cttcaactta cactataaag tatcttaatc acacgatatg ctagccacta aattcatcat
    19621 atttgattcc ttttttaaga taatgtagca tctttttatc caataacgca attgttttta
    19681 aggataaatt tcttaagatg gtacatttca aaatggcatt tgacatatga aacaaaaaag
    19741 aaagaaaaga gcataaggga aaactgatag caccttccta caggaaggtg gctaagttgg
    19801 ctgtgccaac tggttttctt tcaaaatcat ttcataattt ttgatatcat aaaaaaatcc
    19861 attttggacc tattttcggt cataatttag tacctacttt tggtcatagt ttcgtccgta
    19921 gttttggtca tagtgactaa ggcttttctg ttcacaaaat tggtttaaat ttgctttctt
    19981 taacacttca tttatatcat agcaattata atgtttacac aacatcattc ctaattttaa
    20041 cggttgttcc tctttatatt ttttaagttc tacatttttt tgcgtttaat tacttttctc
    20101 ttttctttat attccgctcc aactttctct ttaatagtga taatagaatt acatattttt
    20161 gttaaacttc cttaaaaaaa ttggatctcg attactcaaa tttgcttgca ggcttttcta
    20221 attgctttgt tttttcttcc taattatttg attttatttc cattttcttc tagtgaaaat
    20281 ttattatttt taataatcgt acgcgtagaa ctgatttcat tttttgtatc tgtttgatta
    20341 tctaacgttt gaaattcaaa gttttgattg gctttatcaa tatcttttta tactacttta
    20401 tttgcaagat atattttctt gcttaatttg gtcatagttt cattcgtcac ttcggtgata
    20461 tttttttaat ttgcaaataa aaagagttaa accgatatac attaggttca actcttttgc
    20521 aggtttcatg ggtgtactat cacttttaat ctgatagatg taaacctctc tttatctttt
    20581 tgttacttca attttcaaca atagctcctt tataggttgt caatattgct ctacgtattc
    20641 tggcttttta acccattatt tctctaaagt ggaagagaat aatcgcttaa tccccactaa
    20701 ttccttgtcg taaattcatg tcaaatacaa tttttaaaag ccatttaatt catggattat
    20761 ctcttcactt ttttctagat aacaatattt caagttgttt tttatctcat gtttcatctt
    20821 taattcttct tgaatcatca gttcaatata attagtgacc gtgatttttt catttgttgc
    20881 gttctttact gattcacata attcgtcaag ttctaagaaa tcatgcgtac taatctttag
    20941 aattaatttc atgacaattc ccccttttat ttttttaata gattatcgaa aagcggatta
    21001 ggatcattaa gtgtatctct gaataactcg ttgtcttcat aggtaaatct tcgtcttggt
    21061 tttgatccct tatcattttc acggatttca ctatcaataa tcactgtttc atgatttgaa
    21121 tcaaattttt tcgctgactt tctgtcttca acgatattga ttttttgtgt tttttctttc
    21181 atttctccac tatctttttg aacgttctcc cgaacatcta ctgttttgaa tccttgacta
    21241 cttgtagaac tttgtacatt ctctcttaca tccattgatt taaacccttg actacttgta
    21301 gaattttgta cattctctct tacatccatt gatttaaacc cttgactact tgtagaattt
    21361 tgtacatttt ctcgaacatc aattgtctta gtaccttgac catttgaaga gctttgtaaa
    21421 ttctctctta catcaacatt ccgtccgaca tgaccattca atgaaccttg aatattttct
    21481 cggacatcta ctgatcggcc accttgacta cttgtagaat tttgtagatt ttctttgacc
    21541 aatttttcta atccggtatt tgagttttta gcttcttgga ttctttcttt ggtcaacgct
    21601 tctttttcgt ccgtattagc tcctgtacgc ccttctacac gtttccttaa catttcctca
    21661 cgattcattg cttcaggcgt gtatttagct tcttgtcgct tctgattaat taattcttca
    21721 gcagacttag cttgaccgtg catagcattt ttacgttctt caatatcttg ttgaactttt
    21781 tgctgaattg cacttacagg attattattc gattcagcat tatttttcat tgcttcacgc
    21841 atacgttcag aactagacat aattctatcg gcattttcaa ccttagcacc atcttttcta
    21901 tccgaaagac gtgttggcat ggaatcagca tattttccag tttcatcttc tttattttta
    21961 gctaacatag gtttgctatt tttattaata gcggacactg taccatcatc taaaccttct
    22021 ttgaacttat tcttggtatc attagccata tcacgcatac tcttaaatgg ttttattgct
    22081 ctttcactag ccattgtagc tccatctgaa gctaaacctg ataatccacg ttcatgggca
    22141 tatcccaaag ctcttccagt tttgccagct ttttttgata gagtttcgcc gaaattcttt
    22201 tctggttttc gatcttctcc ttctccactg tctgatccat ttccatttcc gcttccttta
    22261 gcacgattaa atccagttga tccttttcta aacagcattg cgcccatacc aaaagcagaa
    22321 gcaagttgcc catagccttc tttgagtcca atatcaacac caaagtatct catgactgtt
    22381 ccactgcctt ttatcagcac aaacacagca cagatataag caattgtttt tataaaaata
    22441 tttgtggaga taccttgtcc agcatttaaa aaattgataa acatagcaaa catagatagt
    22501 ccaaaccctt gaaatccaac tgttaagtaa cattgtaaaa tatcggataa aacaactttt
    22561 gaacgttgtc ctgtttcaat atctgtcgca aaaacaagaa cacctaacac acgtttaaat
    22621 gcaagttcta atattgctgt aatgatcaca aacgcgctga acacataggc gattgccaac
    22681 gctgtcaacc caatcgaaat cccccaaaga tttgcttgat atcgataata acctgatttc
    22741 aagctatcag aaaatgttga taagaagtta tcagaaaact ttgtggcaac aaattcatta
    22801 ttagaatttt caactaattc atagcgaaga ttatccgcag ctggattttc tttttccaat
    22861 ttatcaatca ctttatccgt caacacttgt gttaaatctg tctgttgaaa attttttcgt
    22921 gttaacttat ttcgatcctc cgttttatca atgcttgagt attgatctgt tttattaata
    22981 tatgccagat ctgttactcc ttgttttatc aatgaccaag cgactccgtc atctgaattt
    23041 gtaatcgtag tagcatcatt gtaaaatatt ttggcaaatt gaataccgct agaaatcatt
    23101 gttggcatta aaagaattaa cgctacagac atcactatat tcattccaac agatcttaaa
    23161 tctattgttc cttttccagt aatcatcttg tagccaacaa acatcaatga aaggatcatt
    23221 aatccaacga caattgtatt tatgactgat tgataaacat tatttagccc tgtactttca
    23281 atgaaattga acaaatccaa cacatctgga atcatatttt gaatcgaatc agtcacagta
    23341 aacatgcctt ttaccacagc ccatccaagc caaatcccga actgactaag gaaatctcca
    23401 ttgtattttt ttaggtaagg tctataaaga gaattattca aaaactctgt ttgacttttt
    23461 gtgtcatcaa accaattgaa aatgctagct tcaacaatat tacttgtaaa aacaacgcta
    23521 atcattaaaa caagtacact gagtgctaac cagtttattt ttctactaac gattttttct
    23581 ttaattgctt tcatagtttt ctccttcagc ccattttctt aggctctcag agagctgctg
    23641 agccattttt tgattaatta tgatatgagt tacacaattg tcattttcag ctcttaaatc
    23701 gagaactact gtgttgaagc agatactctc gattaattcg agagtatctg tattttgatc
    23761 aagacaccac atttgatcta ttaagcgatt tttaatcatg attcttctcc tttcaaccaa
    23821 ttatgcatag taatttcagg taactctttg atttcgaaag cttttttgaa ctgatctata
    23881 ggctctacat tttctaaaaa ttgactttta tatcttttct gaagtccatt caaaaaatat
    23941 gttacataat cgtataaccc ttcttcagtt tttctttgaa aaaagcatgc ttcatgttgt
    24001 tttataatac actcagcaat aagatactga gtattttcag ataaatattc aatgattttt
    24061 ctgatatctt ctgtatctac attagcgttt ctcaaatagt gatacacttg aaataatttt
    24121 cgaccatctt cgttatttgc gtcataaaga acactaatct tactgtaaat cctctttata
    24181 ttaatatcct cttcttccat aacgagagta gtctttgata tgttctgtga agtagtcttt
    24241 gtatacgtat atacaaattt gtacatacct ctaccttttt ttaaagagac atatctcttt
    24301 ttttcgatac ccctctgacg aattttcggc atatactcct ttttttcgca atccaaagta
    24361 ggaaaagtaa tttctatcaa tttatgtaca tttaaaacaa tgtacataac atttgataat
    24421 gtaactgctc ttttctcata ataaatattt ctaaaaaccc ttttgataat cccctttttc
    24481 tctaagtaca caattgcatc ttttatagct cgttctgata atcctgtttt tttgcttaat
    24541 tgcttatatg atttttgcaa aatatcttca agaaactttt tttgataacc aagtagctga
    24601 ccatcatcgt taaaaatttt tttaggtcta taccaatagg taatttctgc taagataact
    24661 attgcattca aatagggctt ctcaacacct tttttcgttt tttttcttaa ttgatcgtac
    24721 catgtgtgtg gattacattt ccgtcaaaat ttatttctct aagtttgtca actacaacat
    24781 ttccagaaga aaacaccttt tcaccttctt ttttgatata atagctataa ataaagtttt
    24841 ctcagcactt tattattgag tgttccccca gtctgcaaac ttttgggaac actttttttc
    24901 tttttttaaa gcattttttt ataatttcta cttcatcatc ttccaatatt ttcccctctt
    24961 ttcattcgag caaacataaa ctcattaact gcctttttcg aataaaattt tcttgcccct
    25021 aattcaacta cgggcaatcc ctcatttctc acagcatttt ttaaaaagtt ttcactcaca
    25081 tttaagtatt ccgccatttc tttttgattg agatattccc ttgtcatccc cgcattttct
    25141 tgagcctttt caatagcttt tgtagcaatt tgataaaact gctttagaaa catttcctcc
    25201 tgttcttctg aaatcattaa ttttattgct tccacaaaaa cctctccttt ttaattaatt
    25261 attctataac tcctctacct ttataagtac aaataaatac aaattgcgta aaaaaatgta
    25321 tttatttgta tttataagaa taaagtatca tactccagat aaaaagtaaa tacttttaaa
    25381 tacttttatt ttataaatat gatatactat ctttaaaaat aaaaaggaga aaaaagatga
    25441 agccaaatcc ttcagaagca ggaaaacgaa tcaaacaatt acgcctttca tgtggtttta
    25501 ctatggaaga acttggaagg aaaatagata attcaccacg tgcgaccata tccaactggg
    25561 aacgtgggac caatttacca aatccacaaa agctgaaatt attatcaact atcactaatt
    25621 caacaattga ctggattaaa tggggaactt tagaagaata tataacttca taccttatcg
    25681 atatagggta tgagctatat attaaggact tcccagaaat acctcacaaa gtctttaaag
    25741 acattcaaga aagatatagt gatacgtttt cgctagataa agactatgag ttattgaatc
    25801 ctataataaa aaatatattt acaaaatatt actcaaaaga ttttgaaatt tatctaaatg
    25861 agatacttgc taataatatc aatcctctga ttgaagagta cgctaaccaa agacactcta
    25921 tctctaaaga gctatttttc aaaagagcca acagtaaact tcaagacaag ataagaaatg
    25981 gtgatttcaa atacggtgaa aaagaaagaa tgattgattc tttaaaacag ctattagacg
    26041 aaatggactt agcctataaa gatatttcaa agtattcatc tgtcgaggat ttcttttata
    26101 aaattactaa aaaccaattt gaaacagaaa aatttatttc agatcttagt aaaaaataca
    26161 atttcccata tgagaaaaat agtataatcg caaaattttt aactgataat cacgataaat
    26221 ttaaaaataa ttgattcttc aaataacttc tctacctgca ataatgaagt aaggagagaa
    26281 tcaaatggca acatttttta gttataaatt acaaaatggc gaaaaatatt ggggatttga
    26341 aacttattta gggaaagatc ccaagactgg aaaagatata cgtacaaagc gtagaagatt
    26401 caaatcaaaa gctgaggcgc aaacagcact taatagacta cttgtagact ttaaagaaaa
    26461 acaagagttt aaaatcaatg ttacaacttt tcaagagttg tatgaattat ggattgataa
    26521 ctacagaaca agagtaaaac cgtcttctgt tgccgttgct caacgttttt gcaaaaacca
    26581 tatattacct gcttttgggg aattacgatt ggataaaata agtgttagct attgccaaaa
    26641 acaggtgaat gaatggcaca aaacattaaa acaatatggt ttcttgagaa aaacaactgc
    26701 tcaaatattt aaatttggag tagcaatgga agtctgtaag gataatccta tgtctaaaac
    26761 attgcttcca agaaaaattg aagaagaaca acccttgaag ttttacacga aagatcaatt
    26821 acaactgttt ttacagaata ctaaagaaaa taattcagtt aaactgtaca cttttttccg
    26881 tttattagct tatacaggaa tgcgtaaaag cgaagcattg gcgcttcaat gggaagatat
    26941 agactatttc aataaaacaa taacaattgg taaaactatc gctcaagacg agtttaatca
    27001 agtagttcta caagtaccta aaactaaaaa ttcatcaaga acgattcagc ttgatgattt
    27061 tacacttaaa caactgcgta tttggcaaca agaacaaatg aaaataatga tcttatatgg
    27121 ctataacacg aattcaccaa aacagtttct tttcactaca aacacaaaca agttgtacta
    27181 cctccaagta gtaaacgatt ggttagactg gatttacaaa aagacaccga tggagcctca
    27241 aattactcca catggattta ggcataccca ctgtagctta ttgtttgaaa gtggtgcgtc
    27301 gataaaagaa gtacaggaac gattaggtca taaagatatt aaaactacca tgaatatcta
    27361 tgctcatgtc acaccacaat ctgttaagaa aactggtgac cgatttgcaa aatttatggg
    27421 cgaataattc caaacgtagc caaaaacgta gccaaccatt aaaatacaaa taaaaaaacg
    27481 ctcgaaacgc tttaata
//
LOCUS       DAFENC010000034        26154 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.034, whole genome shotgun sequence.
ACCESSION   DAFENC010000034
VERSION     DAFENC010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26154
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.034"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(56..1087)
                     /gene="queA"
                     /locus_tag="LP493_001906"
     CDS             complement(56..1087)
                     /gene="queA"
                     /locus_tag="LP493_001906"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HBL2134053.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            1280..2455
                     /locus_tag="LP493_001907"
     CDS             1280..2455
                     /locus_tag="LP493_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HBL2134054.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            2459..3100
                     /locus_tag="LP493_001908"
     CDS             2459..3100
                     /locus_tag="LP493_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2134055.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            3097..4014
                     /locus_tag="LP493_001909"
     CDS             3097..4014
                     /locus_tag="LP493_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HBL2134056.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            4011..4682
                     /locus_tag="LP493_001910"
     CDS             4011..4682
                     /locus_tag="LP493_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2134057.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(5223..5711)
                     /locus_tag="LP493_001911"
     CDS             complement(5223..5711)
                     /locus_tag="LP493_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HBL2134058.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(5912..6178)
                     /locus_tag="LP493_001912"
     CDS             complement(5912..6178)
                     /locus_tag="LP493_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBL2134059.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(6178..6441)
                     /locus_tag="LP493_001913"
     CDS             complement(6178..6441)
                     /locus_tag="LP493_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBL2134060.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            6917..7102
                     /locus_tag="LP493_001914"
     CDS             6917..7102
                     /locus_tag="LP493_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL2134061.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(7244..9067)
                     /locus_tag="LP493_001915"
     CDS             complement(7244..9067)
                     /locus_tag="LP493_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HBL2134062.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(9665..12370)
                     /locus_tag="LP493_001916"
     CDS             complement(9665..12370)
                     /locus_tag="LP493_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HBL2134063.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(12676..13623)
                     /locus_tag="LP493_001917"
     CDS             complement(12676..13623)
                     /locus_tag="LP493_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HBL2134064.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            13813..14082
                     /gene="rpsN"
                     /locus_tag="LP493_001918"
     CDS             13813..14082
                     /gene="rpsN"
                     /locus_tag="LP493_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBL2134065.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(14258..14620)
                     /locus_tag="LP493_001919"
     CDS             complement(14258..14620)
                     /locus_tag="LP493_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBL2134066.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(14631..15752)
                     /locus_tag="LP493_001920"
     CDS             complement(14631..15752)
                     /locus_tag="LP493_001920"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBL2134067.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(15768..16118)
                     /locus_tag="LP493_001921"
     CDS             complement(15768..16118)
                     /locus_tag="LP493_001921"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HBL2134068.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(16248..17759)
                     /locus_tag="LP493_001922"
     CDS             complement(16248..17759)
                     /locus_tag="LP493_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBL2134069.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(18081..19433)
                     /locus_tag="LP493_001923"
     CDS             complement(18081..19433)
                     /locus_tag="LP493_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HBL2134070.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYLEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(19586..20662)
                     /locus_tag="LP493_001924"
     CDS             complement(19586..20662)
                     /locus_tag="LP493_001924"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBL2134071.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            20858..22603
                     /locus_tag="LP493_001925"
     CDS             20858..22603
                     /locus_tag="LP493_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HBL2134072.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(22883..23320)
                     /locus_tag="LP493_001926"
     CDS             complement(22883..23320)
                     /locus_tag="LP493_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HBL2134073.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(23304..24677)
                     /locus_tag="LP493_001927"
     CDS             complement(23304..24677)
                     /locus_tag="LP493_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134074.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(24999..25487)
                     /locus_tag="LP493_001928"
     CDS             complement(24999..25487)
                     /locus_tag="LP493_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2134075.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(25509..26111)
                     /locus_tag="LP493_001929"
     CDS             complement(25509..26111)
                     /locus_tag="LP493_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBL2134076.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         7503 a         5560 c         4837 g         8254 t
ORIGIN      
        1 cataaaatct ttgtaaagct tttttgttat tcaaaactag cggcttttca taaccttatt
       61 tcacgaacat cgcatctcca aaactaaaga aacgatagcg ctcttcaatc gcatgctggt
      121 aagcagataa agtcaattct cttcctgcaa aggcactaac taacatgact aaagtcgatt
      181 ttggcaaatg gaaattagtt gagaaagctt ctaccacttt gaattcatag ccaggcgtaa
      241 tgaaaatatc agtccatccg ctgtctgctt tgatttctcc attaaatttc gttccaatcg
      301 tttctaatgt tcgaattgaa gttgttccga cagccacgat tttcccgcca tttttacgta
      361 cttggttcaa tcgctcagcc gcttcttccg tcaaacggta gaattcacta tgcatatggt
      421 gttcttcaat tttatctacg ctgacaggtc ggaatgtacc taaccctaca tgtagtgtca
      481 gatagactaa ttcaacaccc tttgcttcga tctcatcaag taattctttc gtaaaatgca
      541 atccagctgt tggcgctgca gcagaaccat tttctttcgc atagacagtt tgatagcgat
      601 ctgggtcttc cagacgttct ttgatatatg gaggcaatgg catttctccc aatgattcaa
      661 gaatctctag aaaaattcct tcatactcaa agtcaatgat ccgtccgccg tgttccaatt
      721 cttctttcac tactgcttgc aatctgccat caccaaaaga gattcttgtc ccaactttgg
      781 cacgtttcgc aggtttgatc aatgtctccc acgtatctcc ttgtgtattc gttagaagaa
      841 ggacttctaa atgcgcacca gtatctggtt tttctccata taaacgagca ggcagaactc
      901 gtgtattatt cataactagc gcatcaccag gctgtaactc ttcaatgatt tcatggaaat
      961 gtttatcttc catctctcca gttttccgat ccaaaacaag taaacgagaa tgatcgcggt
     1021 cttttaatgg tgtttgtgcg attaattctt ccggcaagtc aaaatcaaaa tcttctgttg
     1081 ttaacatatc gtcactcact ttctatcatg tgcttcatca ttctatcatg tttttcgttc
     1141 tgttggcaaa atcagcactt tttcacttct attttttgtt ttcctaaata aaaaaactac
     1201 cctatttgta ttttttcatt gttttaggca tactagtaat agatagttct tcattgaaaa
     1261 tagaaaaaga ggtggcacca tgattgaatt tcaaaatgtg tcaaaaattt ataaaggtgg
     1321 aaaagtcgct gtagaggacg tcaatctttc atttgaaaag ggtgagttca tttgttttat
     1381 cggtacgagc ggaagcggaa aaacgacgac gatgcggatg atcaaccgaa tgactgatcc
     1441 aacacaaggg aaaattttga ttgatggaaa atccatccaa gaaattgatc cagtggaatt
     1501 gcgacgtcag atcggctatg ttatccaaag tattggattg atgcctcaca tgacgatccg
     1561 tgaaaatatc actcttgtcc aaaaattgtt gaaagtcagt caagaagaac ggaataaaac
     1621 agctgaaaaa atgattgatc ttgtggaatt gccccgtgag atgttagatc gctacccaca
     1681 tgaattatct ggtggtcagc agcagcgtat tggagtcgtt cgtgcccttg cagcgaatca
     1741 agatatcatc ttgatggacg agccattcgg tgcgcttgat ccaatcactc gtgattcctt
     1801 gcaagacctt gtcaaagatt tacaagagcg tttgggaaaa acgatcgtat ttgtaaccca
     1861 tgacatggat gaagcgatta aactagcaag ccgtatcgcc atcatgagtg aaggccgtgt
     1921 gatccaattt gatacaccag aaaatatttt acgtcatcct gcaaacgatt tcgtagaaga
     1981 gttgattgga gaagatcgcc tactacaagc caagccaaat gcgacaagag tcggcgaagt
     2041 tatgctaaat acagcaatca cgattacacc ggaaaaatca ttacaagaag caatcaaact
     2101 gatgagggaa aaacgtgtag atacgttgtt agttaccgat aattcgaatg tattaaaagg
     2161 atttatcgat gtagaaacgt tgaataaaaa acgaggaaaa gtatccagtg tcggcgacat
     2221 tttgaataaa catgtttttt acgtaaaaga atccgcctat cttcgtgata ccttgcaacg
     2281 cattttaaaa cgcgggctga aatacgtgcc ggtcgttgat gaacagaaca aagtcgtagg
     2341 tatcctgact cgtgcatcat tagtggatat cgtctacgat gtgatttggg gagaagatcc
     2401 cgcaactact gatgttgcag agtcagctac tcctgaagaa tctaaggagg tctgacctat
     2461 gcagcagttt tttcatcagc acggttcaga aattctctca aaaggttttg aacatcttta
     2521 tatttcagga cttgctttga tcattggtat catcattgct gtaccgcttg gtgtcttact
     2581 gacacgtttt ccaaaagctg ccacgattgt gattggctta accagtgcct tgcagacaat
     2641 cccttctctt gctttattgg cattgatgat cccgctattt ggcgtaggta aattacctgc
     2701 gattatcgca ctctttattt attcattatt gccgatttta cgtaatacgt acattgggat
     2761 gaaaaatgtc gattggaatt atcgggatgt ggcaaaaggc atggggatga ctgagttcca
     2821 atccattttt tccgttgaat tgcccattgc tatgccaacg atcatggctg gtattcgttt
     2881 agctgccgtt tacgtgattg catgggctac acttgcctct tatatcggcg ctggtggttt
     2941 aggcgatttg atttttagtg gactgaataa ttaccaacca gatctcattt tggcaggtac
     3001 gatccctgta acaattttag cactattggc tgattggctt ctaggtctct tggaacaccg
     3061 gctgacaccg atcgcactta gagaggagaa tgaagaatga aacgtatact aaaaatgacc
     3121 atggttcttt tctctcttct tatacttgcg agttgttcct tccctggtct tgccagcaat
     3181 acagatgaag acaccatttc gatcacaggt ggaatcactt cagaagcaca gatcttagca
     3241 agtctagttg ccggaatggt tgaacattat acagataaaa ataccgcaat catcaacaat
     3301 ctggctacta caactatcaa ccatcaagcg atgatgaacg gagatgcttc aatttcagcg
     3361 gctcgctaca caggaacaga tttaacgact acattgaacc ttcctcctga aaaagatccg
     3421 aaaaaagcgt ttgctaccgt gaaagatgaa tttgagaaaa gatacggtca aacgtggttc
     3481 ccgtcctatg gttttgaaaa tacgtatgtc tttcttgttc gaaaagacac cgcacaaaaa
     3541 taccatctat ctaaagtcag cgatctgaaa aatgtagcgg atgaattagt agctggtgta
     3601 gatacttctt ggatcaatcg taaaggagac ggttatgacg gcttccaaga aacttatggc
     3661 ttctccttca attcgatatt acctatgcag attggacttg tttatgacgc agtcgaagca
     3721 ggaaaaatgg atattgttct tggctactct acggatggac ggatcgccag ttatgatcta
     3781 gtcatgttgg aagatgatcg tcaattcttc ccaccatatg atgctgctcc agttgtagac
     3841 aacaagatat tagctgatac gcctcattta aaagaagcct taaataagtt aggtcatacc
     3901 atcagtacgg aaaaaatgca ggaattgaac tacgaagcag ataataatct agtggaacca
     3961 tcagtagtag cacaacgttt cttacaagaa aaccactatt ttgaagggaa gtgaagcaat
     4021 tggataaaat gaatgtcttt caacaatttt tctattattt ccaggaaaat ggctcctata
     4081 tctttgcaca atttatccgt cacttcctga tttctatcta tggtgtcctc tttgcagcag
     4141 ttgtcgggat tccggttggg atcatgattt ctaggagacg taaattagca aactgggtga
     4201 ttcgtttggc gaatatcatc cagacgatcc cttctctagc catgatctcc attttaatca
     4261 ttggattagg cctgggagtc aatgtcgtga ttgttactgt atttttgtat tccctcttac
     4321 cgatcatcaa gaatacgtat accgggatga tccaagtaga caaaaacatc cttgatgtcg
     4381 gcaaaggcat ggggatgact gctagacaac gactattcat ggtagagtta ccactctctg
     4441 tttctgttat catggcaggc ataagaaacg cgttagttgt tgccatcggg ataaccgcga
     4501 tcggtgcatt cgtcggtgct ggtggtcttg gagatatcat tatccgagga accaatgcaa
     4561 cagagggcac atcgattatt ttagcaggtg cattgccaac tgcattaatg gcgatcatca
     4621 cggactggct tttaggtatt ttggaaagac ggctagatcc agccagccgt acatcacgct
     4681 gatgttattg taaaaaacaa aagcttctgc gaccatttgt tggtcgcaaa ggctttttta
     4741 gttctgtcat ttttaaggca ataatccact ctgattcttc cctccttatg ggcaaagagt
     4801 tgcttttctt agctatttat ccattccgta tactccaact tcatactgcc aacgggttca
     4861 tatctgcatc caccgactaa gtttttttct tatccgctaa ggcattttgc caatccattt
     4921 tcccatcact cgtcatggaa ttcataccac atgatctcta aatactcgtc tgcttgttct
     4981 ttgaattggg catcaattct tacatccttt ggcgtggctt tcatttaagc cttttccatc
     5041 agtcctcgat tgttcgatgc cttcagctgc atcatcaaaa ctggtgactg ccgtatcggt
     5101 aacttcgatc atcttttata caatcgggaa cttgccatcc tcatccttgg ctaaaaacat
     5161 atctagccat tccagcttct cgccatggga ggtttgcggt tcctaaaacc ggtacacgat
     5221 tcttatggac tgcatccgtc gcaactagac ttggcgatac gatgatcctt caccagaaga
     5281 gcacccccgt aaaccaattg atcgatatat tgccaataag aaaagacatt ggcgtaaaag
     5341 atatcgatcc ctcgtgatgc attgccgttg atactgctat tcatggccga aagcgccacg
     5401 actttaactt cttccgtttg agtgacattc atgttcggca atgtcgcttt ggatacccgc
     5461 tctgctaaag gaacgacact ggtattgtat ttcgtatctg tatcttttcc aaaagaccat
     5521 gccaacgaat cctctgggaa ccaataagac gactccggtt gattgtccat tgcttttttc
     5581 aacatacttt tggctgtttc tcgataaacg acatttccaa ttgtcttcgc ctcactttgg
     5641 cgataatcga tggtcgttgc cactgccaac actaacaacg atgctccaat tttactgatt
     5701 ttccttgtca cacttcttcc tccttgtttt acataaaccc gtcaacattc cattcctaaa
     5761 ctcaaacaat gacccttcaa aggtggagat ataggaacaa attaaagaaa tcatgcaata
     5821 aatccaagaa ggttggtttt agaacaaaaa aagagtctcc tttttgggga gactctttgt
     5881 taactatcta aaaaggttgg ctcttctcac ttcactcata atgtgtccag gcagaataaa
     5941 tttctacaac tttattttcc tcatcaactt tgtaaaccac tcgatgctgt ctattcagcc
     6001 tgcgtgagta tctgccttca tgtgtaggtc tcagcttttc aaaagactgc gtgggcatat
     6061 atggatcttc cttcaatgtc tgaatcactt cttcaaattg tttctttaaa ttcgtttgct
     6121 tgatttttct taaatccact ttcgcagagt ttttgattgc gactgtatag ttactcatca
     6181 aagagcttcc caatcaatat catcgatatt cgtaaagcta ctgtcgtctt tttcgcggtc
     6241 tcgtacttta tctaaagtac ctgtttgctc aagaaaaagg gtttcttgaa tcgctctcca
     6301 gtcttccagc ccaatcaata cagcattgtt tccactacga tcactaataa tctcgatttc
     6361 agtatgattt tcatttacct ctttcaataa ctgataaaaa tttttacgag cagtgctagg
     6421 attcatcgtt gtattagcca ttgtctctcc tcctttttct gatataatta tagcgtactt
     6481 gattaagtac gtcaaaaaaa tacaataaag cacttaaatt cagcaaactt ttcctctttt
     6541 ttacatagag aaaaagaccc ctttttaggg aggatctttg tccacgctca cttcttactc
     6601 ctttacgact agcggtagcc aaacgtaaag taattggtaa caacgtatca tctttagcaa
     6661 aggtcgaatc caaagcctgt gagtctatgc aacaacacca atacacgaag gttcctcgtt
     6721 gcagtgtgac ttgattgata tcttgaataa cctgaggata cgcacgaaag atttgtaacg
     6781 gttattcaaa actgattttg gccgtcaagt cttctactgc ctcaaaaatg attgcctctt
     6841 tcgtctcctg tcattcatgt tcactatcga tttgatactt gcttagaccg ttgggtttgt
     6901 gaatcaccaa ttaaaaatgg cactgagtta tggtaacaaa aaatggtcac ttgacgaggc
     6961 tgagattcct acttatgaag acacatggca cttaagagtc gaggtaaagg aagaagctga
     7021 aaatatagga ggctgtacat tatttggcaa aggattcgga aattatgatc aagacatcaa
     7081 aatcaaaatg ttttacagct aaataggaag aataataaca tttcatacgc tgttcccatc
     7141 tttaatggct tatagagggc acctttagct gagaataaga caaaacagac cctctagctt
     7201 caattaagag ctagagggtc tgtttttgat tttaaaactt ggtttatttc ttcaaatggt
     7261 agctataggt gctgacaacg atattttcac gccaagacaa tcgcaatctt aaccgcaaac
     7321 ttgtttggtt atggagaata ttctgccagc gtctgtttgg tacaaattga ggaatcaaca
     7381 cagtagttgt atagttttgt ttcgctgcat ttttacttac gatatctaca taacggataa
     7441 ttggattttc aatcgagcga taagaagagt ggacgattga aaaacggaca tctgggaaat
     7501 gctttttaaa ttctgcttcg atttcttttt ctttttcgac atcttcgtct agcgaaacat
     7561 gcatcgcaac gacataatca ccgatcgaac gtgcgtaatt caacgcaccg atatttaccc
     7621 gtgtcacatt cccgactaat acaagaacgg tattcccgtc ataatcatgt agttttgcat
     7681 cattttctaa acgaagctgt tctgctactt ttttataatg atcatggatc ttataaaaaa
     7741 tgaacataac gattggcata atgatgaaga aaggccaaat gtcccctaac cgatagacaa
     7801 acaaaatcgc aatgattgca tatgagatga acgcacccgt aatattggca atcgatttgc
     7861 ttaaccatct ttttccttct tttttccatt tgacgaccat ccctgtttga gataaagcaa
     7921 atggaatgaa cacgccgata gagtataacg gaatcaagcg ttctgttgag ccatggaaaa
     7981 taaacagcaa tacgatcgaa cctagcgcta gtgtgataat cccattggaa tagcctagtc
     8041 gatccccacg atcttgatac atgtgaggca tgaatttatc ttttgccaga ttgtatgcaa
     8101 gaactggaaa agcagaaaaa ccggtgttag cagcaactgc taaaatcagc gctgtagcaa
     8161 attgaaggac gtaatacaaa ataccatgtc caaagacagc tttaccaatt tgagacaaaa
     8221 cagtgacttc tttttcagga acgatcccat accaatagtt gataaatgtg atccccacga
     8281 agaagaaacc taagatcaat gccatcatcg tcaatgtagc agcggcattt tttgctcttg
     8341 gcttcttaaa gaatggtaca gcattactaa tcgcctccac cccagttaaa gaggaagaac
     8401 cagaagaaaa tgctcgtaaa atcaaagcga tagaaacacc cggcacagcc gctcctggaa
     8461 gtgcagtagc ttgcaatggc acagcacctg tcacgatatt atataaacca acaacgatca
     8521 gtaacgagat cacaaggata aatgtgtaca ccggaaataa taggaacgat gcagattccc
     8581 tcagcccacg aagattcagc atcatcagta gcaaaacgat tgtcacagaa atagcgactt
     8641 gatgaccgta gagtgctggc accgctgatg tgatcgcttc agcacctgct gagacagata
     8701 ctgctactgt caacatgtag tcgatcaata aagagccacc ggaaatcaag ccagcattct
     8761 ttccaagatt ctcactgctg acgacatatg ctcccccgcc atgaggataa gcatggatga
     8821 tttgacgata tgatagcgtt aatgaaatca ataaaataat aacaaaagcg gcaatgggta
     8881 gcgaatacca gatggctgca gcagacaaag cgactaaaac gacaacgatt tgttccgtac
     8941 catatgcaat agatgataac gcatcagacg acaataatgc caaagcagca aatcgggtta
     9001 atttgtgctc atcattttca gcagatttta aaggcttacc tactaacaac ctttttaagt
     9061 aatccaattt ctaaactcct ttacacacaa ttttacttca agttttatag tcgaaaattt
     9121 atagtaaaca agatgttata gtacgctcac tgaccttaaa agtcaataaa ctttaagaaa
     9181 ataattggaa aaaaacagaa aaatatcaag cgctttttca aacgctttaa tacagcaaaa
     9241 atctaacatt tttttatggg ctttttcttt gaattctata ataaaaggat agaacttgac
     9301 ttagaaaatc aagttctatc ctttttgata tcttaacttt tggaagagag atgtaaggct
     9361 gctttctacc catcattctt actactcgaa gcatagcgca gttgtcacaa cctcttgata
     9421 aacggtgttt aaaagcttgc atctgcggta ataagcccaa ccaaattaaa aacataagaa
     9481 gctgttttta tttggtcgtt cttattactt gatgcagagc agctttttta caacctcttg
     9541 gtacacggtg ttcaatcagc tgaccctcgg tattagctca aaaaaacggc aaaatatgag
     9601 gaactatttt tccatttttt tctctaatac tcaggtcaaa acactgattt cacaacctct
     9661 ttttttaatg aaaaatatgg ctctcatgcg ccgcttcttt gaatttcgtc attttttctt
     9721 cgatgaacgg atagattgcc gttcctacga ttccaaagac aacaaacaaa ccgatcatga
     9781 tccagattgc tttcgtagca tttggccaat aaattcctcc tgcagattcc cgtaacaagt
     9841 ttaccgcatg agtaaatggc aagaacggat tgatcatttg gaagaatttc cctgagactt
     9901 ggatcggata gttcccgcct ccgccagaga tcgacagtac taagatgata atagcgatcc
     9961 ctttaccgac attatcgaat aatgcagcca agacatagac gatcatcatg aacgctaagg
    10021 cgatcaagac agcaaatgac acgctgtaga ccggattttg gacatctact cctagtaaga
    10081 aaatattccc taatgtaacg atcaagcttt gcgcaatcgc cattgtcaaa aatgtcagca
    10141 tacgagcaac gaattgttct cgtttcgtaa aattgtttcg gtctttcttt cctaaatagt
    10201 attctgtcgt agcaacactt gaaagaagaa cagcgccgac ccacagacat agtgcagtat
    10261 aaaacggggt gctagctgaa ccgttatttg cgattggata aagcgcattg gtttgtagct
    10321 caacaggttg tgtaaagaag tcactttctt ttgttgcgtc tagtttcaat aatttgatga
    10381 cttcgcctag atcgacttct tgttcgcctt ttcggatcgc gtctgctgct ttttggatac
    10441 cagctttgat atttggccag tcattgttga tcaagtccgc agcagcgttc acagctgttt
    10501 cgacttctgg cattttttca tttactgttg tcaatgtacc ggtgatttca ttttttagtg
    10561 ctggccaatc attttggata aaatcagcgg ccaatcctaa tttttgctga atgatcggta
    10621 attcattgtt gtataggtct gccccttcat tgatgccatt gacgatggta tccatatttc
    10681 cattcagcat tgtattggca tcatggattt cttgtccaat tgcaggcatt tctttttgat
    10741 atttttctaa aattgccact gcattcgtta cagttgcttt cgttgagctg agaagcgaat
    10801 caaagtcgat ctggtccgct ttgctcagtg cgccttgtgc agtcccaatc gtatcgatga
    10861 cttggtctag tagagaagtg acagtggaac tgatttgacc tgtattgata ccagcaatga
    10921 tgccattgat attattaaca acggcatcaa tttgatctag caattcatca atagccttcg
    10981 tgtcttcatt ttgaacagct gtgttcaaag cagataggcg gttttgcaga ttgcttagca
    11041 agggttttaa ttgatttagc tgatcaataa ttggctgtaa tttcgtattt ccagcacttg
    11101 tttgcaattt agtcaggaac tcgaccagtt tatcgattgc attttgttgt tgagatattc
    11161 cgtcaataaa gccgttcaat acattgctga tgtttttctt ttcatcatca gtcagcttac
    11221 catcttcaat agctgttctt acagtatcta ttaacgaacc tgtcgttgtt gccacttgtc
    11281 caattgactt caatgtaaca tctacactgt ttgtgatgct tggtatcgca tctttcagct
    11341 gagaggcacc tgattttgtt tggtttgcta gatcacttgc ctgattttct aaatttttca
    11401 catctggcaa gatatcttgt acttgttgga tgatcgtcaa gccttgtttt gcttcatcga
    11461 ttccttggtt cattgtctct tggatcgaag caaaatcgcc gtcgatctct gctagttgct
    11521 taccggcatt ttggatctct gggatttttt cttgcaaatc aaggatgatt tttgcttgat
    11581 ctttcaactc aggcattttg tcattcaatg caacgacttt ttcacccatc tcatctactt
    11641 tagggatgta atccacgaat tcatttgctt tattcagttt ttccttgatt tcaggtagtt
    11701 gactttgtaa ttcgaggact tgttttgtgt agccgtcgat cgtgtccaaa ttttcatctg
    11761 ttgataaaat catatcttta actttattga tacttactag gttcgtatcg atgtcgtaac
    11821 ctatctcatt gaatactttc aataaagtcg aactggctgt tttgataaat tcatttgtga
    11881 tttgcgattg gatcgaactt gctcctttat cggtgatttt cggtgcaatc gcattgattt
    11941 tttcatttac cgtatattcg atttttggtt tcttgatatc accactagta aaactcagca
    12001 gatcttctga gaaatccttt ggcaagtaaa tacctgcgta atactttccg gaacggactc
    12061 cgtcttctaa ttgttctttt gaatcaacga attgccatcc taattgttta tttttatgaa
    12121 gcgattcgat gacttgctcc ccaatggcca cttctttacc ttgaaactct gctggcttgt
    12181 ctgcactgta aacagcaatt ggcagctctc cagtatttcc atatggatcc cataatgctt
    12241 tgatgttaaa ccacgcatat agcgaaggga tgatcatgat cgcgatgatc agaagtgttg
    12301 caatcgggtt tttgaaaatc cgtttccagt caagcaaata taatcgaagc gtatttttga
    12361 ttgactgcat agttctcccc cttcttcttt tttcagctga attactttac catgtatttc
    12421 atactttttt caatcggctt ttttcaaaaa agtcgaattt ttggacatat cacggcaatt
    12481 gtctcattgt aatctcttac atattgagaa ataattaagg attacagcct ttactttatc
    12541 atgaaataaa agggaaagat aattttatgc caaagttttt atctattata cgtatacgca
    12601 aaaaagctaa aacatttttt gtctttgccc ctacaaaaat gtttcagctt ttttcgtttt
    12661 ttattcctgt atttcttatt tttcgaatga caggatgatt ttcccagcag gaggatgtcc
    12721 ttcaactagc tgatgtgctt ggatgacatg cttaagtgaa gcagacagat tcattgaaat
    12781 aaaaacatga aaggctcctt tttggtaggc tttgattatg ccagcaaagg cttctgcatc
    12841 tagatattcc tttcttggaa caaacgattc ataaaagcct tccttttttt gccgcaaatc
    12901 tagatctggg aggtcattta atgcaacata cctgccgcct ggtttcatga tctggatgcc
    12961 ggtttctcct ttgatacttc ctttcgtcgc atcgattaca aggtctgcct gatcagcaaa
    13021 ttgcagacct ggatttgttt tatcataagc agcaaatgct gaagctccta atttttttac
    13081 cttttcctca tttttactgg atgcactggt taagattcgg attccctttt catggagaag
    13141 ctggatcaga cttgacccga ccgcacctga tgctcctagt atcattacag tatctgtcgg
    13201 ctggatttcc gtcaaatggt tgattagatt ataagccgta attcctggcg tgaccattcc
    13261 ggctgcttct tcccaactca ttttatctgg aatttttgct acttttgctg atggcaacac
    13321 gacttcttct ccgtaagtcc cgccgactgc atggacagct actcgatcac ctacatgaac
    13381 agttgtgaca tctgaaccaa tctctgtcac aataccagcg ccatcattac ctggtacata
    13441 agggaatttc aatgttcgta tctctttcat ttctcctaaa cgcaaggcaa catcataagg
    13501 attcacactg aatgctttta tttctacacg aacatgtcca gaaccgactt ctctgggatg
    13561 agcatcgatt tcttcaaaaa catcttgtgc ttctccgtaa ccgttaattg caaatcttcg
    13621 catggtcacc atctcccttt ttctttaagt ttacgtttat gcctttattt tgacaaaaaa
    13681 aatgtctttt cgttttggcg catgattcaa aacaaaatag ttgtcttttt tcgcgtaacg
    13741 tgttaaatta tttatctaaa agcgtaaaga ttacgattta cgctaataaa aaataattgg
    13801 aggaatttgt tgatggctaa aaaatcaaag attgccaaag caaaaaaaca gcaagaaacg
    13861 attgaacgct atgctgcttt acgccaggaa ttaaaagcgc aaaaagatta cgaaggcttg
    13921 cgtaaacttc ctttagatgc tcgtccagaa cgattgaaaa atcgtgattt aatcgatgga
    13981 cgccctcgcg gatacatgcg taaattcggg atgtcccgta taaaattccg tgaattagca
    14041 cataaaggtt tgattccagg agtaaaaaaa gccagctggt aatccaagtc tggctgtaat
    14101 gtaaaggagg agggcgcatg gaccactcct tggatcatca aaaaagatac gttcgcttct
    14161 tctagcagaa atgctggtac tagaagcaga cgtatctttt tttacgcaca gctggtcctt
    14221 ttttatatgt aaaggctgca tggttacttc gctatattta tttagtaaca ggagtcagtg
    14281 cttcgatacc cacactaatt ttcaatgctc ggtcaacttc tgccataatg ggtcgatcca
    14341 aatggcagac cttttctttc aatcttgatt tatcgatcgt tctgatctgc tccaacagga
    14401 taacggagtc tctttctatt cctgttccag tagctttgat cccaatgtga gtcggaagct
    14461 taggtttagc catttttgcc gttatggccg caacaatgat cgtcgggcta aaatggttac
    14521 ctagattatt ttgaataacc aaaactgggc gtgttccgcc ttgctccgat cccacgactg
    14581 gagaaagatc agcaaaataa atatctcctc tttttaccat aggatcctcc ttattcttga
    14641 tattctcttg gtatccgctg tcctaatccg caagccactt catagtggat cgtacctaat
    14701 tgatctgcta tatcctgcat agtgatttct ttgtctgcat ttttgccgat aagcgtcact
    14761 tttgttccga caggaaattc ttgaggcaat cggatcatca gttgatccat acatacacgc
    14821 ccaatcgttt cacagtagtt cccttctacc aatagagaaa aaccctgcat ctttcgtggc
    14881 cagccatctg cataaccgat cggtatcgtt ccgatccact ctgcttcagg agtgatatat
    14941 gtttctccat agccgattcc ttcacctgct gggagttttt tgacttgaat caattcagaa
    15001 accagctcaa gtgctggctg caatggataa acttccggta gtgcgtgccc agagggatta
    15061 agtccgtaca ttgctactcc ataacgaatc atattgccga ttgtttcatc atgccataaa
    15121 gccgttgcac tattgctgac atgtacatat cgaggaagtt cgggaagttt tttcagcact
    15181 tctataaagc gttctttttg cagattccaa tatgtatcat ctgcctgatc tgctgtagaa
    15241 aaatgggtaa ataaaccttc ccattctaat acacgacttt ctttgatgaa tgcagctgcc
    15301 tcttttactt cttcaggtgt acaaaatccg atacgaccca tcccagtgtc tgcttttaga
    15361 tgaatcgaaa gaggcgtctc tagcttactt ttctctaaaa cagcagctgc tgcttgcaac
    15421 cattcccgtg tacctgcagt tactgataaa tcatgagcaa cagctacagt cagtgcgtcg
    15481 taaggaacca tattcaagat aaggatgggc tgagtaaatc cagcttctct caactcgact
    15541 ccttcatcta aatttgaaac acaaaagccc gaagctccac ctgcaactgc tgcctcagct
    15601 gtttcaatag ctccatgacc gtatccgttc gcttttacta ctgcaaacaa ttcttttcct
    15661 tgcggaagtc ttgcaacttc atttgctaca ttttcagtta tagctttttt atgtatcact
    15721 gctttcgttg ggcggtgcca agcgacaacc atcgtttttc cttctttcta gtcttccaaa
    15781 ataatttgtg caaaagctgt ttcatttgta tgagtaatac tgacccatac attgccttca
    15841 tgaggtgaac gcgtcacaac aggctgacca ttttcatttt ttaaaatctc gacatcttga
    15901 aaggtaactt ttccgatccc agttccccaa gctttagaga aagcctcttt gcaagcgtaa
    15961 cgcccgccta aaaattctac ttggcgatga aaaggcaagg actggaatag tttcatttca
    16021 tcagaggtca agattcgtgc aatgaatttt ggtttttctt cgatcagccg agtgatccta
    16081 ggaagttcga ctgcatcgat cccaattcct tttatcatat gcttttctct tttcaataaa
    16141 tttagaacac tctcattcta ccaaattata accattttgc cacaaataag tccacaaata
    16201 acaaaaatga aagtttctct taaaaaagag aaactttcat tttatgttta atcgttattt
    16261 gaacggatta caaatccgcg ttttttatca ttgtgacgtt taccgccatc tttttggctg
    16321 ttattatttt tgctataacc gccttttgat ttgtttccac gataattacc gccgtcacga
    16381 cgattacggt tgtttccgcc accacgtttg ccatttttat tgtatccttt tttctgcatt
    16441 ggcaatgggc gttctggtgt gatcttcact ggcactgcat cagctggatc ttttgctgtc
    16501 gtttttagca aaagtgcaac taaatcttgt gcagaatatt cttctaataa tttatctgct
    16561 gtttgcaggt atttatctag accattttct gcaagttttg tttcgatttg ttcaactgca
    16621 gcacctaatt gacctttgaa tgcttctttt tcggttggtg gacgtaaagt cgtcatccgt
    16681 tttttcgtca agttttcaat cacatgcaag tagtccattt catttggtgt aacgaaagtc
    16741 acagacatac cgccttttcc ggcacggcct gtacgtccga tacggtgaac gtagctttct
    16801 ggatcttgag ggatatcata gttgtacaca tgagtgacac ctgaaatatc taatccacgt
    16861 gcagcaacgt ctgtcgctac aaggatatct aaatgaccgc tcttaaatga acgcaatacg
    16921 ctcattcgtt tttgttgaga caaatcgcca tggattcctt ctgcacggta accgcgtgct
    16981 tctaatccgc gtgccaattc gtctacacgg cgttttgtac gtccgaagac gattgttaat
    17041 tcaggtgttt gaacatcaaa caagcgagtc atgatatcga atttttcgta ttcttttgcg
    17101 cggacatagt attgatcgat caagtcagct gtcatttctt tcgctttgat cttcacatga
    17161 tgtggatttt tcatgaattt aacgccaata ttcttgatag ctggcggcat cgttgctgag
    17221 aaaagtaatg tttgtctttg atcaggaact tgtgaaatga ttttttcgat atcttccaag
    17281 aagcccatat tcaacatttc atctgcttca tccaaaacta atgtttgaac ggttccaagt
    17341 ttcaatgtgt ggcggttaat gtggtcaagc atacgtcctg gtgtacccac aacgatatgt
    17401 ggacgatctt tcaagccacg gatctgacgg ccaatatctg ctccgccgta aacggcttgt
    17461 acacgtactt ttttgtcgcg ccctaaacga tataattctt cttgtgtttg gatagctaat
    17521 tcacgtgttg gtgcgataac taaaccttgt aattcgtgac gatctggatc gattttttct
    17581 aacattggta atccaaatgc agctgttttc cctgtacctg tctgtgcttg tccaataacg
    17641 tcttttccag ctaatgctag tggaatcgtt tctgcttgga taggcgttgc ttcttcaaaa
    17701 ccagcgcgtt cgactgattt caacaattct ggtgataatt ctagttcttt aaatttcaaa
    17761 tgaatcctcc tatatggttg ttaactgagg atgtagcttt tttgctaccc cgtcgatttg
    17821 ttcggtcaaa gtgtattgtt tctttttgac agtggccacg cacgttttta tccattctta
    17881 gcccctgtgg caccaccgaa aaatcacttt gcgaagttta ggcattagaa aagccaaacg
    17941 ggtcgcgttc agctttatca ttattatgac atctggcttc aacaagttgt ttctatggca
    18001 aaaccagtcc aatttctctt catctttcgg caataggtta ttctaacata gtttttcgtt
    18061 ttctgcaagt ttacagattt ttatttcatt tgctgaagtt gttctaccac ttcaaataag
    18121 cccatgctgt tgctgccttt tagcataata ctatctgttg cttcaagatt ttgtttgata
    18181 gcatcaatca atttattctt ttctttttcc aaatagaaca caggtagttg ggggtatttt
    18241 tggttcaatt cttcttttag tgcatgcatt tgttccccat aaaggaaaat catggcgaat
    18301 ttctcaggat cgatatgttc actcatttgc gcatgcatat ttaaagactc tttccctaat
    18361 tccagcatat ctgctaacac agcgattctg cgtccttttg ttggcagatt tttaaaagta
    18421 tctaatacca gtcccatggc tgttggattt gcattgtaga catcgctcaa aatagctgca
    18481 ccatttcctg ccgttagcca ttcggttctg ttttgagtga tagaaacatg ggcgagccct
    18541 tggcgtatct caggtatgga cagtccaaag aagcgcccga tcgtatacgc aatcaaagca
    18601 ttcgttacat tataacttcc aggcagcggg atcgtaaatg tttctccttc tactacaaaa
    18661 tcggtttgtg cttttccttt tgctgtcact tccgcatgaa catcgccatt tccaataccg
    18721 aatgttgtga ctgtttgtac taatgttgcc gttaaaggtg tcagcaacgg ttcatctgcg
    18781 ggcacaacga gtaatccgtc tgatacaagt ccgtcagtga tttccatttt ggctttagcg
    18841 attccttctc gcgacccaag attttctatg tgtgcttcac cgatcattgt gattgctgca
    18901 gcttttggtt gagccataag tgaaagttcc gtgatttcat tggcgtgatc catgcccatt
    18961 tccaaaacga tcttttctgt atcttggggc atgtgcaaaa tcgtgtaagg aagaccaata
    19021 ttattgttgt aatttccttg cgtcttatat gttttgtatt tttcagacaa gacagacgcg
    19081 gttagatctt tcgtggtggt tttaccattg cttcctgtaa ttgcaacgac ttctgcgcct
    19141 actttttcca agtaataggt tgccaattgc tgcatggctt tcaaaggatc tgctacagga
    19201 ataactggaa aattttttgg agcttgttca acaggcaagc tccaaaatga agcagatgct
    19261 ccgtttgtga tcgcttgctg gataaattca tgtccatctc gcgtaccagc aagaggaacg
    19321 aataaacttc cttcggttat cttccggctg tcaaattcga cattggtaat ctttgtcagt
    19381 gcagagcatt cgctgcccac ggcttgtgca atttcttgta ttgttagatt cattgagatc
    19441 tctcctaaaa aaggttgtga aaaaagcgtt tggcctaaac ggcgggttcg catgactctc
    19501 acttccaagt aaatttctct attcgtattt agaagctaga atgaacgcgg ttacgcaatc
    19561 actccagcct cttctttatt tctctttatt catttttttc aaaaaaagat tgacgctgat
    19621 ggtatcgatt cattcctaac tggatcagtt cttcaatcaa atcaccgtat ttcaagccca
    19681 tattttccca taagagtggg tacatactga actccgtaaa tcctggcata gagtttaatt
    19741 cattcaggaa taattcattt ttatttgtca aaaagaaatc gcaccggctc aatccgcttc
    19801 cacctaacat cgtgtaagct aacttcgcgt actcttgcgc tttttgataa acttcttctg
    19861 gcacttcggc tggaatctgc atttcgattt tattattgat atattttgct tcataatcat
    19921 agaatgctac gtcttttacg acttcaccag gcaaagtcgt ccgaacgtct tcatttccta
    19981 atacagcaac ttcgatttcg cgcgcttcaa ttccttgttc aacgattgct cgagaatcat
    20041 actgataggc tgttgctaaa gcattttgca gctcttctcg gttttctgct tttgtaatgc
    20101 cgacactaga acccatattc gccggtttga caaacatcgg ataaagcaaa gaaccttcac
    20161 attgatcaaa tactttttta ggattttctt tccattgatt cttaagtact ggtacataag
    20221 gaacttgcgg cacaccagca gcttgtaaaa tatacttggt catgatttta tccatggcac
    20281 atgcactggt caatacgcct gcgccgacat aaggcatatt caatgtctct aagaagcctt
    20341 ggatcgttcc atcttccccg tttggcccat gtaaaactgg aaaaacgatg gctccttctt
    20401 ctttgatttc gcccggattg atcacttttc ctgtaaagcc ttcctctgtc tgtccacttg
    20461 ggtcccatga aagatgcaag acatctttgc tggcaggttt ttctgttagt aatggacctt
    20521 tgacccattg tccttctttt gtaataaata cgagttgaac ttggtaataa ttataataaa
    20581 tggcatttaa aactgaaaat gcggaaagaa tggacacttc atgctctgcg ctgcgtccgc
    20641 catatagtaa agtaatcttc aaaagattgt cctcctgtat tctaaatcgt tcagtgattt
    20701 actctcatat tttagcacaa aacaaaaata aacgaataac ttatttataa aaaaacgagc
    20761 cagcttctaa aagaacgagc gtcatttatt ttttgtcagc tagattattt gtcccgtttt
    20821 ttataaaaag ttatgataaa gaaaaggagg gatgatgatg gcgcaaacaa atccacgcag
    20881 ccgcttggca gaaatcattc gagtgttcat caattacaat gtagtgccaa actttgtaca
    20941 gcaaaaaaat cccgaacagg taaaaaaagc ctttgaagaa ctaggcccca ccttcatcaa
    21001 gataggacag atgctttctg ttcgagaaga tttgctttct tctgccttca ctcaaacatt
    21061 caaaacatta caagatagtg tacctagcga cacattttca acggtcaaaa agacgatcga
    21121 aacagaactt tctctttcat tatcagatat attcgatgat ttttcaaaat cgccttttgc
    21181 ctctgcttct atggggcagg ctcatcgtgc caagctgaag aacggtgacg cggtagtcgt
    21241 taagatccaa caccctaaca tcgccgaaga gatccgactt gatcttcaac tatttgaacg
    21301 agcgatccct ttgatcaaat acattcctga aactagcgta gttgatctaa aaggggtact
    21361 ccaagaagta aaacgttcct tgatcaatga aatggacttc ttaaaagaaa gtcaaaatgg
    21421 cgaacaattc tatcaaaaga acaatggctg gaaagagatc cgcagcccca agatttatga
    21481 cgctttttgt tcgaaaaaag tgatcgtgat ggaagaaatg tctggtaaaa acttgaatca
    21541 tttaatgaac gccgaaaaca aaactgaaac ttttatcact ggaattcaaa acaagcagct
    21601 gaaacaagaa gttgcaaagc ttttagttga gaactttatg aaacaggtgt ttgatgatgg
    21661 ttttttccat gctgatcctc atccagggaa tctgctattc catgtactaa caaaagaaga
    21721 acagacacaa gctagccgaa aaactgaaac agtccatgaa aaagagttcg gttcctttgc
    21781 ttttcgagcc tccacttctg cagaagaccc tgttgcgcca tataccatca actacatcga
    21841 ttttggtatg atggggcatc tttctgcagg acttaggcaa aaactcacac aagccgtttt
    21901 agcgctgtat acgaaagatg cttatcgaat cgaaaaagcg gtccttcgac tttgtcagca
    21961 agaaggctcg tttgatgaaa gtcggttcca ccaagaactg acaagttttc ttgaacagta
    22021 ttatgattct cctattgatg aaatcaactt gcaagaagta ttcacacatg tcgtgacgat
    22081 ttgtcatcaa aataatctgc agttcgatcg tgatatcacg cttttgctga aagcatttgg
    22141 gacattagaa ggggtgatcc gcgtcctcga tcctgaagtt tccctcatgg aagtcgcttc
    22201 gccttttgct caacattatt ttctcactca tctggatgta gaagatacat tgaaacaaag
    22261 cggattagac ttattggaag ggatgaaggc tgcgcctaag atccctcaac agctccacca
    22321 tctattagaa atgtggactt cgggacaagg aaaagtcaat ttggaattga aaaagcaaga
    22381 caaattattg agcaggatcg aaagtatgat caatcggctt gttttcggta tgattttagc
    22441 tgcattgatc gtagggtcct ccctgcttgt ccaagcagca cctgtagaaa acgcagaggt
    22501 cgtttcctta ttagggatat ttacgtatgc tattgccgca ttcgtcatta tttttttggc
    22561 aatcgatgca ttgatccaaa tgtataagaa gaggaaaaag tagaaaaagg ttgtgacaga
    22621 aagaatcagc ttcaagaaat aagaaggggt tttacataaa ttgtttctca aatttttgtg
    22681 aaaattcggc ttatttttcg aagaggctac ttctgaaaca ccgagaataa aaaatgtgaa
    22741 aaagctgttc tgcacccagt aataagaaca atcaaaaagg gaacatggaa cacatttatc
    22801 ctgtttccct gttccctttt tgatgtattc gagcataaat aaaatacctt cgttacctac
    22861 tatcttctgt acttggtaaa ccttagtcaa ttgccttttt taacgcttga cgaaaagaca
    22921 tatgatcttt ctccgtaaag ggttttggac cctttgtcct tatgccagct tttcttaact
    22981 ttccactatg ataacgttgt tctagaagcg tgccgatatt cgcttcgtca aattcttttc
    23041 cagagtgatg gaacactcgc acacccttcg gcaatacaag tgaagctaaa ccataatctt
    23101 gcgtgatcaa aaagtcattc ttcttaacca taccgacgat tttataatcc gcactatcag
    23161 ctccgcggtc tacgtagacg atttggacat gattagcgta ttctttggtc gtataatggt
    23221 ccacactggt cacgataacc acgtcaagac cataggattc tcctaatttt atgacatctt
    23281 cttttactgg agaaccatct ccatcaatga atagcctcat tctttttcgc cttcttccat
    23341 aaatgataaa cagttactaa tccgctcagt aaaagaccaa cattgatcca ttttgccaag
    23401 ataagcagtt gtacactttc tatcggcact gattcatggt tcagcgtgat caataataga
    23461 tggattggct ctcccatttc ttttgctaaa acaaacaaaa gcgtcatcaa taaaaactgg
    23521 tggatcacac tccctttatt ttgagtagta tacttgacaa cgatccggcg atccattgga
    23581 atagctgtat cagtttgata atattcctta tttagccagc tgcctgttac tacgtgccag
    23641 aaactaagca gaaagacacc tatcgcaaaa ccatttggaa tcaagaggac caataaagaa
    23701 gaactcagtc caagcaattg catagccaat ggagaccatg ttaaacgttt caaaatccat
    23761 ggtccgacta tttttgctgc aatcaagcct gctgcataag gcaaatacat aaaaatcgaa
    23821 agtttttcta atccgtacag tatgccaaca taaaaactgc taaataaaaa aaggaaattc
    23881 cctagcattc catttagaaa agtaaacaga tttagccagc ttggcaactt ccattccttc
    23941 ttctggtgtc ctaaaacaaa cacgaacaag atgaacagca gcaagaaacc ataaatagca
    24001 agatcaaaaa gcctttcatc gaataacaat cgggcatttc tcaaaagaaa caataagcca
    24061 aagaatatca aaaataaaac aagctctcgc gtagctacca gatttctttt gatgtctttg
    24121 aaatccagtt cgtaacgcgg ataatgacta accgtatggt aggccatgac gtaaaaaagt
    24181 gtataaatag taaagcttgc tgcaatctga gtcggtgcag gcaactcaat cgcttgatac
    24241 aggagaaata gccagatagc tgcaaataag tactttttcc catccatatt gataaaacct
    24301 tgcgtctttt cgtgaaaatt gaccgtggta ttagcaggta caagccatgc tgcactcagc
    24361 cctagcaaaa cacttgaaaa ataaaataaa ggaaaataaa atacgcctaa tattccaagc
    24421 aatgaaccag caccaccaat cagcagagcg atcatcagca acgtgtaact atctagacca
    24481 aatcgtagac tgttgactaa aaatagtcca gtcatccgaa aggcataaaa cagcgtaaat
    24541 ggcaaaatcg tcagccaatt atgcgagtct gttagtccca aaaataaaag ataaggaata
    24601 aaaataaccg tgttacttaa gataaagggc gttgtttgtg taaaattacg cccaaatcgt
    24661 ttgagttttt cgaacatgac aatggctcct taaacagtct tataactaat ctgctcttcg
    24721 attttagcat taaaggggaa ataaaccaat tttacagaat atattcttgt aaaaaaaaat
    24781 acagaaagaa gcataagctt ctttctgcat ttttacggta cttgattact caagcagaca
    24841 agcccttctc cacaaaagtc ttgcccgaca cccctgcatc cggcaggtga taaagataga
    24901 aatcaattat cctgtgcctc caaaatcaat taggagctct gtaaaccaga gtccttctcg
    24961 acccgtcgca taaatttact ttaacacagt tcctatgttt atgcgagagc ttttttcatt
    25021 ttataatcga ccatttgaaa tccttgaccg atatctgaaa taagttcttc tgtaatctca
    25081 aatccttcat gcttataaac ctcgattgct tgatgattcc cctgattcac tcgcaaaaag
    25141 atctctcttt cctttgtttg cgcagcaagt tcttcatacc agcgaaaaac tgaagaagtc
    25201 aatccttgac cacgtacttt atttagcaaa tataatttac ttaaataaat ttttccattt
    25261 atctcttcat aagcagtgta accgacagtc ttttcttcgc tttttaataa aaagtaggac
    25321 acaccttctg tcagttcttt ttgaatctgt ttttttgact gataagtttt cagcatgtaa
    25381 tccacttgtt tttgaccaat gatcggcaca aaagcttccg gccatacttc ttgtatgact
    25441 gccatcagct catccagttc attttctgtt acttttattt tttccataca cccacgtcct
    25501 tttttacatt ataaatgacc ttgcgcttga tggaataaaa agagcatgat catgctatac
    25561 acacccaccg accatggttt caagaaaatc acaatctgca taaattccct aaaagataat
    25621 ttcgtcaaac cagctactag acagatcaag tcgtctggcg caaagggaag cagcaaggta
    25681 acaactagta cttttttaat atctttcgtt tttcttgtca gcaattcatc aaatttctga
    25741 tacttttttg gcgataaaat aagctggaca aaggctacgc catagtaacg gacaagcaaa
    25801 aatccgattg cttccccaat cactaggcca atacaactat ataaaagccc aaatccattg
    25861 ccaaacatca gcatgcccgc tactgaggag atccctcccg gcaaaatagg aatgatcact
    25921 tggatcactt gcaacagaac aaatatcatc actgcatact tgccaaattg ctggataaac
    25981 gcttgcaaag acgtgctcga tcgaaaaatc ccatgatgat aagcataaag aatcaacaca
    26041 aagaaaaaaa acagaccaat aatgggcatg atctgaagac atttttgtaa aactgatcct
    26101 tttttagaca tctatattcc ccacatcttt tttcatttat taaaactgcc tcct
//
LOCUS       DAFENC010000035        25495 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.035, whole genome shotgun sequence.
ACCESSION   DAFENC010000035
VERSION     DAFENC010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25495
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.035"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            127..3654
                     /locus_tag="LP493_001930"
     CDS             127..3654
                     /locus_tag="LP493_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HBL2134077.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3651..7373
                     /gene="addA"
                     /locus_tag="LP493_001931"
     CDS             3651..7373
                     /gene="addA"
                     /locus_tag="LP493_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HBL2134078.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7442..7783
                     /locus_tag="LP493_001932"
     CDS             7442..7783
                     /locus_tag="LP493_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2134079.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8092..9135
                     /gene="pheS"
                     /locus_tag="LP493_001933"
     CDS             8092..9135
                     /gene="pheS"
                     /locus_tag="LP493_001933"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HBL2134080.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9140..11560
                     /locus_tag="LP493_001934"
     CDS             9140..11560
                     /locus_tag="LP493_001934"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HBL2134081.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11730..12740)
                     /gene="trpS"
                     /locus_tag="LP493_001935"
     CDS             complement(11730..12740)
                     /gene="trpS"
                     /locus_tag="LP493_001935"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HBL2134082.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            12994..13731
                     /locus_tag="LP493_001936"
     CDS             12994..13731
                     /locus_tag="LP493_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBL2134083.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13745..14560
                     /locus_tag="LP493_001937"
     CDS             13745..14560
                     /locus_tag="LP493_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBL2134084.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14573..15220
                     /locus_tag="LP493_001938"
     CDS             14573..15220
                     /locus_tag="LP493_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBL2134085.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15236..15892
                     /locus_tag="LP493_001939"
     CDS             15236..15892
                     /locus_tag="LP493_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBL2134086.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16054..16875
                     /gene="racE"
                     /locus_tag="LP493_001940"
     CDS             16054..16875
                     /gene="racE"
                     /locus_tag="LP493_001940"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HBL2134087.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16878..18233
                     /gene="rph"
                     /locus_tag="LP493_001941"
     CDS             16878..18233
                     /gene="rph"
                     /locus_tag="LP493_001941"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HBL2134088.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKEQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18234..18752
                     /locus_tag="LP493_001942"
     CDS             18234..18752
                     /locus_tag="LP493_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBL2134089.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18859..19359
                     /locus_tag="LP493_001943"
     CDS             18859..19359
                     /locus_tag="LP493_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBL2134090.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19639..20559)
                     /locus_tag="LP493_001944"
     CDS             complement(19639..20559)
                     /locus_tag="LP493_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HBL2134091.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20724..21737
                     /locus_tag="LP493_001945"
     CDS             20724..21737
                     /locus_tag="LP493_001945"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HBL2134092.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(21847..22602)
                     /gene="fabI"
                     /locus_tag="LP493_001946"
     CDS             complement(21847..22602)
                     /gene="fabI"
                     /locus_tag="LP493_001946"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HBL2134093.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22822..23262
                     /gene="fabZ"
                     /locus_tag="LP493_001947"
     CDS             22822..23262
                     /gene="fabZ"
                     /locus_tag="LP493_001947"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBL2134094.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23377..24138)
                     /locus_tag="LP493_001948"
     CDS             complement(23377..24138)
                     /locus_tag="LP493_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL2134095.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24327..25421
                     /locus_tag="LP493_001949"
     CDS             24327..25421
                     /locus_tag="LP493_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBL2134096.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
BASE COUNT         8447 a         4424 c         5383 g         7241 t
ORIGIN      
        1 cgtatactta aaaaagtaga aatatcagaa ccttaaaagg atataatttg aagaatatag
       61 aacaaatgtt cagtattttt tgatataata aaggagcacc gtatcatgtg ttgaaggagg
      121 aaaagcatgt ctttacaatt tattcttgga aacgggaaaa aagatcaccg tcaagtcttg
      181 atcgacgaag catccgcttg gctcgaccag gatgcaagta accaagtatt tttccttgtt
      241 cccaactaca gcaaattcga acaggaacaa gaaattttag cggagatgcg aagaagaagc
      301 ggaaaaaaaa ctttcagcac aacaaacgtt caagtattta gtttttatcg tctggcttgg
      361 tatttgctgc aacagacaac tcttcttaca ggaaatgaat tatcagaatc aggatctgca
      421 atgatcttgc gacagatttt agaaaaaaat gaggaagaat taacaatctt tcgcggagaa
      481 atcaataaaa gagggtttat tcgtcaatta caagaactct acagtgaatt gcgtacagga
      541 aatattcaac cagaagacct gatgctttta tttggtgatt cacctaatgc agaagaccag
      601 caacttaaaa tgaaagactt gaagctgatt ttttcagctt atgacagcga attgactcaa
      661 cgtgcactaa caaatgaaga tgcactatct atactagcaa attatatgca gacacaagat
      721 ttcaacaacg tcaaatttat tgtcagtggt ttttctcgaa tcaatggtca agagtatcaa
      781 ttactgcagg caatgatgga aaaggggcaa ttggttgtcg atttattgct ggatcgtcct
      841 tatacagcgg atcttccaga agtacttacg ctctttcatg agactggaaa gctttatttc
      901 cgtctttttc aaagtgcaag agaacggaaa gtccctatat tagtggaccg atttgcacca
      961 gagcagactc gtccgacaga gcttcaactg ctgcaaacaa tgtgggaaga gacatctagc
     1021 caaaagaaag cggcagtaca caaaataggg ggacaagagc atctccattt gtgggaagct
     1081 gaaaatccaa ctgaagaagt ccgacaatta gctgttgaaa tcagacgact agtcagtgaa
     1141 gaaaactacc gttatcgtga tatccaagtg ctgacaaaaa atatgtcttt atatggaaat
     1201 atccttcggc cgatctttca agaaatggca attccttttt atatcgatga agaacaaatg
     1261 atggaaaatc atccgctgat cgaatggatc aacagtctgt tcgctcttga ccgctattct
     1321 tatcggctaa gtgatattat gcgttttttc aaaactgaat tatttctgtc gacggaagca
     1381 gaaaccgaac ttgatgaatg gaaacaagag cgagatgaat tcaggaaaaa actggacatc
     1441 actgaaaatg tagcacttgc ttacaattat caaggaactt attggactcg tgaaaaagac
     1501 tggcagtttg tggcgtatga ttttgaagca gaacagattg aagacgtaca gtatttggaa
     1561 gaacagtcaa atacgattag acgattattt cagaaagctg taccagtatt tttgaaaaaa
     1621 ataaagaaaa gcaaaacagg acaagaggcc gcaaatgttt tttatcaatt tttgatccaa
     1681 agtggcgtac agcaacaatt attgttttgg cgtaatcagg aagtagacag aggaaactta
     1741 gaagcggcaa gaaaccatga gcagacatgg ggagcgctga ttgatctgtt ggatgaatat
     1801 gtagtaattt atggtgaatc ggcttttgac tggtcactgt tccaagaaat cattacaagt
     1861 ggtctagaaa atctaagtta tggtaaaatc cctaccgcaa tcgaccaagt gcgaatcaat
     1921 cgtttggaat tagttcgacc aaatcaagct gccgtcactt ttgcattagg gttgaatgat
     1981 caagtgtttc cagaccgaaa agagacaaaa ggattgttgt ccagtgaaga acgagaagta
     2041 ttaaatcagg ccttgccaga tggacagttt ttattcgacc catcaaagga aagtatctct
     2101 tttgagcctt tccaagccta tcttgttttt ctttccggaa cagatcgatt atatcttagt
     2161 tatgcacaaa gctatgacac agatggttcg ctgaagatgt ctccttattt gcgtagaatc
     2221 acagaatatt tatctgttcc cgtcgagaga aaagagcatt tgacgatcga aagcgaccct
     2281 aattgttatg tagggactta cagaagcgga atcaatacag tcaataggat ttatcgatta
     2341 gctttagatg aaaaaaaacc tgtaccaaag cactggcaaa agctcaaaga attagtactg
     2401 aattcgtcat ggcgaaattt tgctttacag atttttgaaa gtcaggaaca tttaaatgtt
     2461 cctgtttcga tgccagaaaa aatggcggaa gagctttatg gaaaagagat ttatacttca
     2521 atttcacgta tggagaattt ttataattgt gaatacaaat acttcatgca atttggtttg
     2581 aaattgaaag aacgaactgt ttatggtcta actccagcag caactggtga tttttatcat
     2641 gaatcattgg atcgtttctt caagctactg ttttcaaacc aattatcctt agtgaatatg
     2701 tccgatgcgc agcgtagaga ctttactgaa aaagtgctgc aggaagtatt cggagaactt
     2761 cggtttgaga tattggatag ttctgcaaga atgaactata tccgctacca gttaggacag
     2821 acgattcaaa aagtgacatg ggctttgcaa aaacagagca aaaatacagg catgcatcct
     2881 cttcagacag agattctatt tggtcagatt gctggagcaa aaggtatcac aggtctggaa
     2941 ttaccgttga gtaatggtgg aaaactccat gttcgaggga aaatcgatcg aatcgatgta
     3001 gcttctgaac aagaagatac ttggctaagc gtcgttgatt acaaatctag cggacgttca
     3061 ttcgatgtca cagaagctta ttatggcatg gctatgcaat tattgacgta tctggacgta
     3121 gcattgatgg atgcggtacg tttgactgga aaggcggctg ttaaaccagc aggatcatat
     3181 tatttacatg ttcataatcc tgtattgacg gagacagatg atgtagagaa gaatacattg
     3241 aaaaaattta gttatgatgg cgtttttgtc gatgatcccg ctcttttaga agtactagat
     3301 cattcactgg aagcaaaaga acaatcactg atctatccag tgaaaaaaaa tgcgaaagat
     3361 gaataccaaa aaggtagttt cagtaaagac aaatttttca cggaagaaga actgcaacta
     3421 ttcatggcgc ataatcggga aaatatgcgg ttagctggag atgcgattac ttccggagaa
     3481 atcaaactaa atccagctta taaagataaa cagcggattg cctgcgaatt ttgtccattc
     3541 agaagcatct gtacgtttga tgtgatgctg aaagaaaata attaccaccg tctggagaaa
     3601 atagataagg aagaagcact gcgtagaata ttgaaaagga gtgaagaaga gtgaatcaaa
     3661 ttcctttaaa accgcaaaat gaacgattca cagatgatca gtggcaagcg atttttgatc
     3721 aaggagataa tctattagtc tctgcgtctg ccggatcagg taaaactaca gtgcttgttc
     3781 gaagagtgat tgaaaaacta aaaatgggtt ttgatatcga tgaattattg attgtgacat
     3841 ttactgaagc tgccgcaaga gaaatgaaag aaagaattca agaggcatta caagaatccg
     3901 tcaatagcga aagtgaccct gtacgtagac agcattttac taagcagtta gttttattgc
     3961 ccacagcgaa tatctcaacc ttacatgctt tttgcctgac agttattcga cgttattatt
     4021 acttaattga tattgatcca gtctttcgca tgttaacaga tgaaacagaa acgatcttga
     4081 tgaaggagga tgtgtgggac gagctgagag aagcacttta tgcagaaaat gatgaacgat
     4141 ttttccaatt aacaatgaat ttttctaatg atcgttcaga tgacggcttg acgaatctgg
     4201 tgttttctct ttatgagttt gcccgtgcca accctgaccc ccaaaaatgg ctagaacagt
     4261 taagcgataa ttatcgtttg cctgaggggc tagcgaaatc tcgattatat caaaaacaaa
     4321 tccgtccttt agttttggca gatatatacc aatgtgtaca gttatatgaa cagatgactc
     4381 agttagcaca aggtgaagga ttagaaaaaa tgcatgagca agtagctgga gaacaacagc
     4441 agatcaagaa tatctatgaa gcgttctcgc aagatcggtt agaagaagct tatgctggtt
     4501 tggaacaact aactttttca acttttaaga gcagtcggaa agcagaattg aaagaaattt
     4561 ccaatgaagt caagggcatg agggataaag caaaaaaact gattcagcag ataagtaaaa
     4621 gttattttcc tgtttcccca agccaaatgg aagaattaac ggacaaagca ctaccgttag
     4681 tcgaagaaat gacaaaagtc acgcaaagct tcatggacgg tttcagtatg cgtaaacggg
     4741 aaaaaggtgt gctggatttc aatgatctgg aacatttagc gttgcagatt ctcacagaaa
     4801 aaacgaaaga tgtatggctg ccaagtgaag cttcaaaaca ttatcgaaaa aaattcaaag
     4861 aagtaatggt agatgaatat caagacgtga accaattaca agaagccatt ttatactggc
     4921 taagagaacc cgatgataca aaaggaaata tgttcatggt tggggatgtc aaacaatcca
     4981 tctattcttt ccgtttagca gatcctagtt tatttatcgg gaaatacgag aatttctcaa
     5041 agaaagaagg cggacgtcga atcgttttgg ctgagaactt ccgctctaga aaagaagtcc
     5101 tttcttttac gaatcttatt tttgaacaac taatggatcc agcagtgggt caaatcaatt
     5161 atgacgaagc agccaaactg atccaaggat tttcagactt tccagagaat gaacagtttg
     5221 agccggaaat catgatctat gaaaaagaac aggaagaatc agagattgag attccgacgg
     5281 atgatatact ggaagacaaa acagaaggcg aactttttat gacaggacta aaaattcgtc
     5341 aattaattga ttcctccttt atgatttatg ataaaaaatc aaaaaaaagt cgtccgatag
     5401 agtacaaaga cattgttctc ttgacaccta caaagaagaa caacttaacg attttagaga
     5461 ttttcaaaac attggatatt ccattagaga tgaatgatgc tcaaaactat tttcaagcga
     5521 cagaaattcg cacgatgatc tcgctgctac aattaatcga taatccctat caagatattc
     5581 cgcttgcggc tgtattgcgc tcaccgatcg tgggtctgat tgaaccagaa ttagccagca
     5641 ttcgattagc taaccgtgca catacttact atgatgctgt gcttgcttat caagcatcaa
     5701 acgaagatga attagcagct aagctggaac attttggcaa gcaactagag cattggcgag
     5761 aacttgctcg ccgttcttcg atcactgact tgttatggga tatctattat gagacgggat
     5821 atctagagta tgtggtcggt ctgccagcag gggcacagag acaagccaat ctttatgcat
     5881 tggttgatcg tgccaaagct tacgagcaaa gttctttcag aggattatac cagttcgtgc
     5941 gtttcattga aaaaatgcaa gaaaaagata aagacttagc agaaccagtc atttcaatag
     6001 aagataatgc tgttcgcgtt atgacgatcc atgcaagtaa aggcttggaa ttcccagttg
     6061 tatttttgtt agatatgaca aaggagttca acttacaaga cttgcgcaat cggtatgctt
     6121 ttgaagaaaa acttggagca ggaattcgct atatggatcc tgaaacacga gtgttatatg
     6181 atacgttacc gtttcaagcc atcaaattgg caaagcaaaa caaattgttg tcggaagaaa
     6241 tgcgtaaatt gtatgtagga ttgactcggg cagaacaaaa gcttttcatt gtcggttcct
     6301 ataaaaataa agagcaaatg atccaaacgt ggtctgaagc agctgatcat gaggagttag
     6361 tttttgatcc tgcgctacgt ttgaagggca gaagcagctt gatgaattgg attggttacg
     6421 gattgatccg tcatcctgaa atgcagaaat acttagagga agaaatttcg acttctcttc
     6481 ttcaacattc aaatgcacag ttttctattt catggatgaa tcagcaatcg atcattgaac
     6541 aaagacagtt gcttgctgaa aaagaactgg ttaacttaga tcagcagatg aaagaagatg
     6601 aaactttatt agcagattcg ttacaaaaac gtctggcata tgaatatcct tatcaagctt
     6661 cttcacaaac cacaagttat caatctgtat ctgaaatcaa acgattattc gaagatccag
     6721 atgatacaca agaatcacgt ttgactctgg aaagcagtca gaacaaagca gcatcccgtc
     6781 aatttcgtta tacgcaagaa caactagcag aaccaaaatt tttgcaaaaa gatcggcaag
     6841 tgtcagcagc tgctgttgga actgctacgc atgctttgtt acaattactg ccattagaga
     6901 tgccaactac agagagtatc catcaaaaat tacaggaatt ggtaaggaaa cggttagtag
     6961 acgaaaaagt cgcgaaaaaa gtagatgttt cttctattat atggttcttt caaacagaac
     7021 ttggtcaaca gctgattgcc aacaaagaaa acgtaaaacg agaacaacct ttttccatgc
     7081 tgcttcctgc tgacgaagta tttcaagact atccaaatca agaagatgaa ctattaatcc
     7141 acggaatcgt cgatggatac ctagaagaaa aagatcatct caatatctat gattttaaaa
     7201 cagattttat tttacatccg gatgatccag cagaaataga tgcaatcgtc caaaaatatc
     7261 aaggacagct aagactttac caacaagcaa tgtcagaagc tttgaataag ccagtagaaa
     7321 atgttttcct aattttgctt cgagtgaaac aaattataaa cattaacaaa taattataat
     7381 tgagcaaact tgacttatgt tttgtaagga ttatgctata ctctgggaag aggtgagtat
     7441 gatggagcta acacagacag aattcgtttt atgccctaaa tttgaaaaaa cattctctat
     7501 tttaggaaaa aaatggaacg gattgattat cgatgtacta ctcgaaaacg gtccgcaacg
     7561 ctttgttgag cttgcggcaa aaatcccgat ggtcagtgat cgagtattag tcgaacgctt
     7621 gaaggaatta gaaaaagaag gaatagtcac tcgaaacttt gcctgtagcg aaaagagccg
     7681 ttcagaatat ctcttgactg aaaaaggagc agacttgcaa aaagcgatgc gtcaaataca
     7741 agtttggagc gaaaaatgga tcacagagga agaatgcggt tgattttgta aaaaaaatct
     7801 tgtaaactat agtccatacg aataagtaaa gaacgatgac gaaaaagagt agtttggcta
     7861 aaccagttca gggagatctg tcgcagactg aaagcagatc ctgtgtttga aaaatgaagt
     7921 tcactttccg agttcgtctg ataaaatcag accggcaatt gtcgttaacg aagtaagagt
     7981 gcggtgtaag tcatttatcc gcaaattagg atggtaacgc gaagacctcg ttccttaaca
     8041 ggaatgaggt ctttttgttt tgtatttgga atttaaagga ggaacaagca catgtctcta
     8101 caagcacaat tagagagctt gaaagaagca acgctcgtca aaatcacagc ggcacaagat
     8161 ttaaatgaat taaatcaaat acgtgttgaa acgttaggaa aaaaaggacc gatcacagaa
     8221 gtattacgtg ggatgaaaga tctaagtcca gaagagcgac caaaagtcgg aagtttcgca
     8281 aatgagatcc gagatctttt gacagaagag atcgagcgaa aaaaacaagt attagaagaa
     8341 gaagcgttaa atgcagcttt ggcaaaagaa acaatagacg tgacactacc tggtagaaaa
     8401 gtaaaacatg gtacacgtca tatcgtgaca caaatcatgg aagaaattga agatattttt
     8461 gtgggtatgg gctatcagat cgtagaagga tatgaagtag aatctgatca ttacaatttc
     8521 gaacggatga atctgccaaa agatcatcca gcaagggaca tgcaagatac tttctatatt
     8581 tcagacgaga tattgattcg gacacatact tcaccagtcc aagcacggac aatggaaaaa
     8641 catgatttct ctaagggtgc tctacgaatg atctcgccag ggaaagtctt ccgcagagat
     8701 acagatgatg cgacccacag tcatcagttc catcaaattg aagggctagt tgttgataaa
     8761 aacatcacaa tgggcgacct taaaggaaca ttagaagtcg taatgaaaaa aatgtttggg
     8821 gaagatcgtg aaattcgttt gcgtccaagt tatttcccat ttacggaacc atcagtagaa
     8881 gtagatgtca gctgtttcaa atgtggtggt gccggttgta acgtatgtaa atacactgga
     8941 tggatcgaaa ttttaggagc tggcatggta cacccgaatg tgttgaagat gtcaggaatc
     9001 gatccagaag aatattcagg ctttgctttc ggccttggac cagaccgcgt agctatgttg
     9061 cggtatggag tgaatgatat ccgtaatttc tatcaaaatg acttacgttt cttaagtcag
     9121 ttcaaggggg agtaagaaaa tgttagtttc atataaatgg ctcaatcgtt atgtagattt
     9181 atcgaatgta acaccaaaag aattagcgga taagatgtct gtgacaggaa tcgaagtaga
     9241 gggagtaacg gttccagaag aaggcttgaa aaaaatcgtt gtcggtgaag tcaaggaatg
     9301 cgtaccacat ccagattctg atcacctttc tatttgtcaa gtcgatattg gcgaagacga
     9361 actgtctcaa atcgtttgtg gagcgcctaa tgtgaaggtt ggaatcaaag tgattgttgc
     9421 acttcctaac tcacgtatcg ctggtaatgt aaaaatcaaa aaaggaaaaa tgcgtggcca
     9481 agtatcaaat ggcatgattt gctcattaca agaaattggc tattcagata gtgttatacc
     9541 gaaagaatac gctgaaggta tctattatat gccacaagaa gctgtaaatg gcgatccagt
     9601 ttttccttat ttggatatgg atgattcgat tattgaatta tctatcacac cgaatcgtgc
     9661 ggatgcattg tcaatgcgtg gcgtagctta tgaagttggg gcaatttatc gtcagactcc
     9721 tacattcgat gacgaaaagc tggtagaatc ctcacgtcct gctagcgata aaattcaagt
     9781 ggaagttgaa gataaagaag cagttcctgc ttatcaaatc agaatcattg aaggagtaag
     9841 aatccagcca agtcctcaat ggctgcaaaa tcttttgatg aacgaaggca ttcgtccaat
     9901 caacaatgta gtagatgtga cgaactatat tttgctttta ttcggacaac cactacatgc
     9961 atttgactac gacaaattga aatcaaaaga gatctttgtc cgccgtgcaa aagaaaatga
    10021 aacattagta acactagatg gagaatctcg ggaattgaca actgacaatc tcgtcattac
    10081 taacggcaaa gaaccagttg ctttagctgg tgtcatggga gggttagact cagagatcac
    10141 gaatgaaaca acaacagttg cactagaatc tgctttattt gatccaattt cgattcgtcg
    10201 tacagcaaaa caatttaatt tgcgtagtga atcctctgca cgttttgaaa aaggaatcaa
    10261 ccatgcgact gttggagaag ccagtgaggt tgctgcagca atgatcgttt ctcttgcggg
    10321 tggggaagtt ctacaaggcg cggtcaaagg ctcagagatc aaagcagaag acgtatcagt
    10381 gaagatttca cttgaacgca tcaatcaata tttaggaaca tctcttgtcg ttaaagaagt
    10441 aaatgagatt tttgaagcac ttggatttag ctatgaagaa aaggagtatg tttattccgt
    10501 agtagtacca ccaagacgct gggatatcca aatcgaagca gatattatcg aagaagttgc
    10561 tcgtatttat ggatacgacc agttgccatc tacacttcca agtggagaaa cggttgctgg
    10621 aagcttgtca aaagaacaag aaactactcg taaaattcgt acaatctttg aaggaagcgg
    10681 attgagcgaa gcaatcagtt atgcattgac aacagaagaa aaatcaagac agtttgttat
    10741 aaatgaaagt aatattacac gtttggactg gccaatgagc gaagaacgtt ctgtattacg
    10801 aatgaatttg atcagcggac tattagatga tatcagttat aacactgccc gaaaaaatac
    10861 agagattgct ttatatgaaa ttggtcgggt gttcttccaa gaaaatgatc cacgtacaca
    10921 tctgccgcaa gaagtaaaac atgcagcaat cgctatttct ggtatttggg aagaaaaaga
    10981 ttggcagacg aaagctcaaa atgtagactt tttcaccatc aagggtcttt tagaaaactt
    11041 atttgaacaa ctaggcatca ctgaagatgt ccattatcaa acagtgacag aaatgaagga
    11101 aatgcatcct ggaagaactg ctgcgattta ccttggcgaa aaatttattg gttttgtcgg
    11161 tcaagtgcat ccaacgatta caaaaagtta tgatattcca gaaacatatg ttgctgagtt
    11221 tgatttatct gctatagtgg aagctgctca aaaagggatc gttttcgaag cagtgacaaa
    11281 attcccagca gtcagccggg acatcgcttt gcttgtaaaa gaaactgtga caaatcagga
    11341 attaacagaa gttatccgtt ctgctgccgg aagattttta acagatatcc aattatttga
    11401 tgtctatcaa ggagaaaaca ttgaaaaagg acataaatcc atggcgtata gcctgacatt
    11461 cgtcaaccca gaagcaacat tgacagatga agaaatcaat aaagcaatgg aaaaagtcga
    11521 aaaagcgttg gtagaaaacc tagaggcaag tattcgctaa gaaggaaaat atagtaagta
    11581 acgatcaagt agcttttgaa gaccatacat ttgaaaaaaa gatgtgacac aacttcgtca
    11641 catctctttt tttgatttta aaaaaggaat agcacagaga cgagataaaa aaacaggcct
    11701 ttacagcctg cttttttaga gtaaatgaat taatggaagt aattgattcc cattgctgat
    11761 tttacttcag aaagtgtttg tgcagctact ttagcagctt cttcactacc tttacgtaag
    11821 atttccataa cagctgaagg atctttttcc aattcttctc ggcgcgcacg gatcggtgca
    11881 aattcagctt ccaatacatc aatgaggtat cgtttgatct ttacatcacc aagtccgccg
    11941 cggcggtaat gagctttcat ttcttcaatt gcttctttat ctgttccgaa tacatccaag
    12001 taggtgaaga ccatattccc ttctacttgt ccaggatctt gtacatggat gtggtttgga
    12061 tcagtataca tactcatgac ttttttctgt aagacatcgg caggatcgga gatataaata
    12121 ccgtttccta acgatttact cattttgcca tttccatcga ttccaggtaa tctacccatt
    12181 ccttttggtg ggaatacgcc ttttggttcc accaagactt caccatatgt atgattgaag
    12241 ctttgtacga tttcctgtgt ctgctctagc attggttttt gatcctcacc aacaggtaca
    12301 agattcgctt tgaatgcagt gatatctgct gcttgagaaa caggatagat aaagaatcct
    12361 gtaggcacgc tttcaccgaa ttttttttgt tcgatttctg ttttgacagt cggattgcgc
    12421 cgaacgcgtc ctacgctgac taagttcaaa taatacatgg ttaattcagc taattccgga
    12481 atttgtgatt ggataaataa agtagatttt gcaggatcta atcccacggc taaatagtct
    12541 aaagcaactt gcaagacatt tgatgaaacc ttctcaggat ttttagcatt atctgtcagt
    12601 gcttgcatgt cagcaatcat gacaaacagt tggttgtctt catctgcctg catagccact
    12661 cgggttttta gagaaccgac gtaatgccct aaatgcagct tcccagttgg tcgatctccc
    12721 gttaaaataa tatttttcaa aaaagacacc tctttacgat ttgtaagtct gagcacttaa
    12781 tatcttaccg tttttcctga aaagaaacaa cagttcctaa ggaaaaaaca aggaaagagg
    12841 ataaaataac taatagatta gaaatggaag aaatatttat gggagaataa acgttctaag
    12901 aaactttaca aattactaaa ctatcagata taatgtattt tattatacat ctttaaaaga
    12961 aatcttacta aataataatg ggagtgtaat tctatggcaa tgattaaatt tgatcacgtg
    13021 gataaatatt atggcaagtt ccacgcatta aaaaatatca atctcgaatt cgagaaagga
    13081 gaagttgtcg ttgtcattgg tccttctggt tcaggaaaga gcacgatgct tcgctgtatc
    13141 aatggattag agacgatctc ttcaggtaag ctgctgatta atgatactga cttgcatgat
    13201 aaaaagacaa aactgacaga agtccgaaaa aacatcggca tggttttcca acatttcaat
    13261 ttgtacccaa ataaaactgt tctggaaaac atcaaattag caccaatcaa agtgttgaag
    13321 caagaccagg caactgcagt caaaaacgcg gagaaatttt tgaaaactgt caatatgtta
    13381 gataagaaag attcttatcc ttccatgtta tccgggggac aacagcaacg ggtggcaatc
    13441 gccagaggtt tagcgatgaa tcctgagatg ctgctgtttg atgaacctac ttctgctttg
    13501 gatccggaaa tgattggtga tgtattagac gttatgaaaa aattggctca tgacggtatg
    13561 tcaatgattg tcgtgacaca tgaaatgggc tttgccaaag aagtggcgga tcgtgttatc
    13621 ttcatggctg atggagaagt attggaagac agcagaaatg tgagagactt tttcgaaaat
    13681 ccaaatgaag tccgagcaca gcaatttatc agtaaagtta tcaatcattg ataggaggaa
    13741 aaagatgcgc aggttaaaaa aaatacgcct gattttcctt ttaggcattg cttttcttgc
    13801 actagccgga tgtaaaggaa atgggttggc aaatgaagat attttagagc gaagcaaatc
    13861 taccaatgaa atcatctggg gtgtcaagta tgatactcga ttatttggaa tgatggatat
    13921 tgagagcaga actgtacaag gatttgatgt agatattgca aaagcaatca ctaaaaagat
    13981 ccttggtgac aatggaaaaa cagaatttgt tgaagtcact tctaaaactc ggattccatt
    14041 attgaaaaac ggaaatatcg atgcaattat tgcaacgatg acgatcacag atgaacgaaa
    14101 aaaacaggtt gacttttcag atgtctattt cgatgctggc caagctttgt tggtaaagaa
    14161 aggaagccaa atcaaaagtg tagatgattt gaatgcttct acaacggttc tagcagtcaa
    14221 aggttctaca tcggctgcga atatccgaca gcatgcacca gatgcaaaaa ttttagaatt
    14281 agaaaactat gcagaagcat ttactgcttt acaatctggt cagggagacg cgatgactac
    14341 ggataatgcg attttgttag ggattgcaga tgaaaatcca gagtatgagt tagttggtgg
    14401 aacgtttact aatgagcctt acgggattgc gatcaacaaa gggcaagaaa acttcttgaa
    14461 agctgttaac caagcgctag aggaaatgca tgcagatggc acatacgata aaatctatca
    14521 aaaatggttt ccaaatgaaa ctgaaggaaa agtagagtaa gggggagagg caatgagcga
    14581 attgatacaa acttatggac caatctttgt cgacgggttc aagatcacat tgttttcgag
    14641 tgtcttagca cttgtgttta gtttgattat cggaacgtta atggcaatct tccaattatc
    14701 aaagaataaa gtagtgagcg ccttagcaaa ggcatatgta gaatttttta gaaacattcc
    14761 attattaatc atcgtgatgt ttttttatgt tgtcgtaccg atttattggt ttaatctaga
    14821 tggattccaa gcaggtacga ttggattaac gatctataca tctgctttta ttgctgaaac
    14881 agtacgttca gggattcaaa ccgtaccaaa aggtcaaaca gaagcaggac tatcttctgg
    14941 ttttacctat tcagaaatca tgcgttatat tgttttaccg caagcattca aaatcgttat
    15001 cccgccatta ggcaaccaat ttatcaacct cgtaaaaaac tcatctattt tagcaatcgt
    15061 agctggttta gatttgatgt atcaaggaga cttgatcgct agtgaaacat tcaatacctt
    15121 cgatacgtat atcatcgttg ggttatttta cttagttatc acgctaccgt tatcttactt
    15181 aatggtttat cttgagaaaa aatgggcggt tcgttcatag aaggagggga aatacatgga
    15241 ttttagcggc gctttttcat ggatgaatat ccgtttttta ttggaaggat taaaggttac
    15301 tgttgaagtt tcattgtttt cgatcatttt tagtttcttg atcggtggtc tgacaggtgt
    15361 gattcgtttt gcgaatatcc ctttcttttc caaaatcctt ggtgtagtga ttgatattat
    15421 acggaatctt ccattattat tgatcatttt cttcacttac tttgccttac ctcaaatcgg
    15481 cattcagatg aacatcttct ggtccgctgt cgcagcatta acgatttttg agtcagctat
    15541 gttgtcggaa attttccgag ctggactcaa tgctgttcca aaaggacaga tggaagcagg
    15601 attatcaacg ggactgactt atgtagaatc gatgcgaacg atcgtgttac cgcaagcatt
    15661 taaatcaatg atcccggcaa ttgtgagcca attgatttca ctgatcaaag atacttcatt
    15721 agcagtaatc atttctttac ctgaactttc tcatcaggca cgtattattt atggacagaa
    15781 caccaattat gtgcttccga tgttcatcat catgacactt atgtacttcg tggtatgtta
    15841 cgcgctttct ctgctttccg gttacttgga aaagagacgg tacagttatt aatagatgat
    15901 tcttttagcg gttgtggcaa actaaagtca caaccgcttt tcctctttcc attcgaaaaa
    15961 aagagatttc gattgtttta agcaagtaag agcacttgaa aattcacgct aaaaagtaca
    16021 caatagggag gatagaattt attgaaaaaa aggatgatac gattgacaga taatcgccct
    16081 atcggattta ttgattcagg tgtcggcggc ttgactgtag taaaagaagc cctgaaacaa
    16141 ttaccgaatg aaaatatttt atttgtagga gacacagcac gctgcccata tggccctaga
    16201 cccgcggaac aggtaatcca gtatacttgg gaaatgacgg attatctggt ggagcaagga
    16261 atcaagatgc tggtgatcgc ctgcaatacc gcaactgcgg tggctttaga agaaatcaaa
    16321 gctgctcttt ctattccagt catcggtgtg atccttcccg gtactagagc ggcagtaaaa
    16381 aaaacacaaa ataaacaagt tggcattatc ggtacgattg gtacggtaaa aagtcaagct
    16441 tatgaaaaag cactgaaaga gaaagtacca gaattgactg tgacaagtct tgcttgtccc
    16501 aaatttgttt cagttgtcga aagtaatgaa taccattcat cggtggcgaa aaaaattgtg
    16561 gcagaaacat tagctccttt aaccactaaa aaaatcgata cattgatttt gggatgcacc
    16621 cattatccat tattacgccc catcattcaa aatgtaatgg gagaaaatgt tcaactgatc
    16681 gattctggag cagaaacagt aggtgaagta tctatgctgt tagattattt caatttgagc
    16741 aattcaccgc aaaatggtcg gacattatgc cagttttata caactggctc tgccaaactt
    16801 ttcgaggaaa tagctgaaga ctggcttgga atcggacact taaatgtaga acatatcgaa
    16861 ttgggaggaa aataaggatg cgtcatgacg ggagaaaagc ccaagagctt cgcaaactgg
    16921 agcttcaaac aaatgttttc aaatatccag aaggatcggt agtgatccgt tttggtgata
    16981 caacagttat ttgttctgca acaatagaaa attctgttcc cccttttttg agagaaacag
    17041 gaacaggatg ggtgacagca gaatatagta tgctgcctcg agcaacgagt acgagaaatc
    17101 gtagagaaag cagcaaaggg aaactttctg gtagaacaat ggaaatccag cgtcttattg
    17161 gtcgttcctt gcgtgcagta gtagacttgg aaaaattagg agaacgtagt atcatcgtag
    17221 actgcgatgt gatccaagcg gatggcggta ctagaacagc aagtatcact ggggcatttg
    17281 tggcattgaa attagccatt gaaaaacttt taagagaaaa agaattgtca gaagatccaa
    17341 taaaagaaca tcttgctgca gttagcgtag gaatcttacc agatgggact tgcgtcacag
    17401 atttggatta ccaagaagat tccgcagcac ttgtagacat gaatcttgta atgacagaat
    17461 ctggaaaatt cgtggagatt caaggaactg gagaagaagc aacgtttgat ggtgaacagt
    17521 tgaatgaaat gctctttttt ggaaaaaacg cgattgaaga tttgatcaaa gagcaaaaac
    17581 atgctttgct aacagagttt gctcaaaatg atgagcggat agaagaaaca aaaacaatca
    17641 tcattgcgac aagaaatcca ggaaaagcag aagagtttcg aaatatgttc aaagaagcgg
    17701 gatatcatgt aaaaacatta cttgactatc ctgaattgcc agatgtggaa gaaactggca
    17761 gcacatttga agaaaatgcc cgattaaaag cagaaacgat tgcacaattg cttgatcagc
    17821 cagtcttagc agatgattca ggtttgaaag tggatgcttt aggcggtatg ccaggaatct
    17881 attctgcacg ttttgcaggg gaacaaaaaa gtgatgcggg gaataacgcc aaattattat
    17941 atgaattgac agatgtgccg gatgaaaaaa gaacagcaca attccattgt acgttagtat
    18001 tcgcggcacc caaaaaagac agccttgtag tagaagcgga atggcccggt cgagtagccc
    18061 gtataccatc tggcgaaaat ggctttgggt atgatccttt atttatccca gaaggtaagg
    18121 aacaaacagc agcagaatta tcgagcgaag aaaaaaacaa gatcagtcat cgggctcaag
    18181 caatgaaaaa attgagtgcc gagtggaaac aatggctgga aggagagaga tagatgcggt
    18241 atttagtagt aagtgataat catggagaca gagatatcct cgttgactta gtagatcgtt
    18301 atcgttctga agtggatatc tttttccatt gtggtgattc ggaattagaa gcttctgacc
    18361 cattatggga tacattccaa gtggttcaag gtaattgtga ttatggacca ggattcgaac
    18421 agaaaaaagt gatccaaact ggtcaggata cagtattcat gactcacggt catttatcga
    18481 atgtccgatt tggtttgaca cagttagcaa tcgaagctcg agctgcaact gccgatatgg
    18541 tgttttttgg tcatacccat caaataggct gtgagatgga tcagaaaatc ctgtttttga
    18601 atcctggtag catttctcag cctagaggcc cgatccaaat cccatcatat gctcttatcg
    18661 aaagtttaga tgaccaaatt tctgttcaat actataaccg tgcccatcag gcagttgaag
    18721 agttggcctt ttctttttcg agagagcgct gaataaaaaa actctaattt ttaataaaaa
    18781 taagctttat tttatgaatt ttgcatccgg tttcggtaaa atagtagtgt tgaatgaaat
    18841 agaaatggag gccatcagat gattggacct atagtaagag aaatgctgct ggaaaatcag
    18901 gaaacgtttt tgattcctgc agaaaatgtg gcaaatgtta tgtatcatca tccattgtcc
    18961 catggtttac ttgtgttatc gaaggtcggt tattccaaaa ttcctgtatt aggaaaagat
    19021 gatcactttg taggactagt aagtttatca gatgtggtca ataaaatgat tgacttgcaa
    19081 acaatcagca tggacccgtt agaaggacta acggttgctg atgtgacaga aacagatgtt
    19141 ccgacaattg atgaaaattg ggaactagaa gaagtactcc atttgttagt cgattcgcct
    19201 tttttaccgg ttgtcacaga agatcggatt ttcaaaggaa tcattacaag aaaagagctg
    19261 cttaaagccg taaacttcat ggtgcatgaa ttagaacgtc gtaatatatt gtctccgaaa
    19321 atcgaagaat taaaagaaca aatcgatatc gtgagctaaa gaacgagaaa ctaaaagata
    19381 atcaaaaaat aagtagaaaa aacagcgtac cagttttgac tttatcttga aaaagaggct
    19441 gggacaaaag cgtttaactc caagaaataa gaaggaattc acgaaaattg cttttcaaat
    19501 ttttgtgaat ttcagcttat ttccgaagga gttgcttctg cttccgccgt ttatacgtgt
    19561 ttagagcgtg ggacaaaagt gttctttact tttgtcccac gctcttttta gtgagattcg
    19621 ttgcatcgtt tgtccaaatt attttccgac agcaattgga ctgttcggaa tcgtgaaacc
    19681 agaagctgtc aattctttga cataggagct caagaactct tcttttaagg catattgttt
    19741 tccgttcaat gcgtagcaga ccgtacgaat cgcaaaattg ctgtttccaa gatccactaa
    19801 tccaaagata gaaggttcag tttggagctc ttcttggtat ttttcagcta atgtacgatt
    19861 tactcgatca atgatctcat agattttgtc atatccttct tcaggaacaa tccgaatatc
    19921 taaaagtact tgcatatttg cacgagagag attgctgatc gtggtgatgt ttcgattcgg
    19981 gatgaaatgg acagtaccat ccgttgcttt cagctgaagg gtacggatac caacagatac
    20041 gacggttcct tcaatcgtta agtttgctag cttgatgtag tccccaacat ccatctgttg
    20101 ttccatgata ataaaaaatc cggtaataac atcactcatg aacccttggg caccaagacc
    20161 gattgccaca cctgcaattc cggcaccagc caaaagtgat ccgatcggca caccgatagc
    20221 agataaaatt gcatagataa aaaagaaacc aagggtataa tgaaaaatag tatttaaaag
    20281 actatgtaaa gtctttaagc ggctctcgtt tagaatggct tttttagaat actgattaaa
    20341 agacttatca atcagatatt ttcccacacg gtgaagaatc caaaaaagga cgatcaaaaa
    20401 aatcagatat aaactttttt ggataaaggc agccaaaatg gcgtcccaat caatcccgtc
    20461 ccaaaaccgc tgaaacgcat ttactttgct gacagcttga tctgtcaatg tctcgccaga
    20521 agagtctgtc gtaccggcag ttgctaataa tgaaaacata aaatcctctt ttctaaaatt
    20581 tgattctttc tgtattgtac caagaagttt tcaaaaaagg aaatagcaaa aataactata
    20641 atgaaggaaa aaagctgaaa ataaaatgac aaataatatg gataatgata aaatgtggag
    20701 aaaataacga aggtggtaag tatatgcaaa tcgattggaa caatctaggt ttttcttata
    20761 tcaaaactcc ttggcgtttt attgccaaat ggaaagacgg acaatgggaa gaaggagaat
    20821 tgacagaaga taattacctg acgattcatg aaggctctcc agcgcttcat tatggtcagc
    20881 aatgttttga aggtctaaaa gcttatcgtc gaaaagacgg caaggtcaat ctctttcgac
    20941 ctgaacaaaa tagtcgacgg atgaatcaaa gtgctagacg attgctgatg ccaatggtcc
    21001 ctgaaaagat gttcgttgat gctgtcaagc aagtggtaaa agcaaatgaa gattttgtgc
    21061 cgccctatgg aacaggcgct acattatact tgcgcccttt actgattggg gtcggtgaaa
    21121 acattggtgt ccatccagct ccagaatatt tatttgtcgt cttctgtacg ccagtaggag
    21181 cgtatttcaa aggtggacta aaaccaacga attttattgt atctgattac gatcgtgctg
    21241 ctcctaaggg gactggtgca gcaaaagtcg gcggaaatta cgcagcgagt ttacttccag
    21301 gaacagaagc aaaagaactg gattactcag attgtgttta tcttgatcca gccacacata
    21361 cgaaaatcga agaagtaggt gcagcaaatt tctttggaat tacaaaagac ggaaaattca
    21421 tcactccgca atcgccctct atcttaccaa gtatcacgaa atattccttg ttgcagttag
    21481 ctgaagaacg actaggactg caagcaattg aaggagatat tttcattgat gatctagatc
    21541 aatttgcaga agctggtgca tgtggtacag cggctgttat ttctccaatc ggtgggattt
    21601 atcacaataa caatcttcat gtattttata gtgaaacgga agtaggacca gtaacaaaac
    21661 ggttgtatga tgaattgaca ggtattcaat ttggagacat agaagcacca gaaggctgga
    21721 ttgaagtcgt ggaataattt caaagtaatg agttgaaaaa aacgtaaaaa gaaaaaatca
    21781 ggaagagact ttaaaaagtt ttttcctgat ttttatatgt tttactttaa agaatgcaac
    21841 aaaagtttat gaaagatgga cacctttgtc aacgtagata atatcaccga tgattccgct
    21901 ggaaagtggg ctgattaaga aagcacaagc attaccgact tcttcgatcg tcacaccttg
    21961 ctgatcaggc gtacgagatt cagataactg gatcagtttt tgatagtctt taacacctgt
    22021 gacagctaat gttttgattg ccccagctga gattccattg acccgaattc ctttaggcga
    22081 gaactcagct gccaaataac ggatagcagc ttcaagagaa gctttcgcaa tacccatcat
    22141 gttataattc gggattgcgc gttctgaacc tagataagtc atgctaacga tcccgctgtt
    22201 tggtgcaaga aacggttgtg cgtattttga tacagcaatt aaagagtagc tgctgatatc
    22261 ttgagctaat tgatagccgt ctctggaaat atcagacaca tttccggaca attcttcttt
    22321 gttggcgtaa gcaactgcat ggacaaggcc gtggatctcc ccagcatatt caccgatggc
    22381 attcattgct ttttcgatgc tttcgtcgct agaaacatca cattctacag tgaatgcttc
    22441 ttcgccgacc aatttgacta atgatttttt cattcgttca ttttggtaag tatagataat
    22501 ttctgcccct tgtttcaaca ttgcttcagc acaaccccaa gcaatgcttt ttttgttagc
    22561 gacgcccata atgacgattt tttttccttc tagaaatgac ataatgactc tcctttgttt
    22621 ctgataaaaa tttgatagtc gtaaaaaaat agagaataat agctaaaata acttcttgat
    22681 ttcttaatta ttagtcaaaa tgttttgatt gtcaaactat tttttcttaa attaaaaaaa
    22741 gattgctaaa tatttaggaa tatgatactt tgatagtcaa agtaatgaaa atggcaattg
    22801 cctgaaagaa ggagtttaat tatgtcttac gtattatctg ctactgaagt aatggaattg
    22861 attcctaatc gttatcctat ttgttatatt gattatgtag atactttaga accaggaaaa
    22921 aagatcgttg cgacaaaaaa tgtaacaatc aatgaagatt ttttccaagg tcactttcct
    22981 gacaatccag tgatgccggg tgcgttgatt ctagaaacac tggcacaagc aggttcgata
    23041 cttatcctaa aatcagaaga gtttctagga aaaagagctt atatcggtgg gatcaataag
    23101 gccaaattcc gtcaaaaagt tgttccagga gatgtgctga aatgtcattt tgaaatcacc
    23161 aaaatgaagg gatcagtcgg tacagcgtta tctgcagcat atgtagatga taaaaaagtc
    23221 tgtgagtgcg agttcacgtt catcgtcaac caaaatgctt gactataaaa cctgatatag
    23281 caaaacaaaa ggaagcttac ttgcttttta tgtaaaaaga agacgcctga atcctagcat
    23341 acgttgtcat ctatgcagga ttcagacgtt atttttttat ttttgttttg cttcttgcag
    23401 tatattgatt ttatcgattt ttacttcttc ttttggtttg tctgaactat ctgtttcgat
    23461 atttgcaata gcatccacga catccattcc ttcaatcact tggccgaaga cagtataatg
    23521 gccatctagt gaaggataac cgccgttttt ataagcgtcg atgattgctt gaggatagtc
    23581 gtcttttaaa agaccatcat gcatatcatc tgtattttga acgataaaga actggctgcc
    23641 gttactgtta ggatcttgtg agcgagccat agataacgca cctcttatat tataaaggtg
    23701 gttgttgatc tctgtttcaa atccttctcc ccaaatgctt tcccctccag tgccatcgcc
    23761 tttaggatcg ccaccttgga tcatgaaatc tttgatgacg cgatggaaag tcagtccgtt
    23821 gtagtaaccg tcttttgcat gtgtcataaa gttttcaacc gcttttggtg cgtgttcggg
    23881 aaataatttg attttgattg tgcctttatt cgtcaccatt tcgaccagat cttcattttc
    23941 ggcgacatct ttcgtcaatt gtggtaattc caatgcgttc aaatcgacgc tactggcagt
    24001 cgtgctttcc gcagtagatg tactttttga actttctgta gacgaactag aagaagtcgt
    24061 gttgtttgca gaacaaccag cagcaaacag caatgctgct gctaaactaa tacttaaaat
    24121 aactttattt ttcttcataa ctgttccttt ccaatttact attttgttat ctttaatgat
    24181 aacaaaatag agggaaaata cctacttaaa ttattggaat ttatcattta ttttaaaaga
    24241 aaaagaaaag gtgtagacca tttactttgt gtttgctata atgtaagtgg atacaaaaac
    24301 gaaaagatgc aggaggaaat ggtaatatgg gaaaattagg aatctcgatt tatccagaac
    24361 ggtcaacatt tgaaaaggac aaagcgtact tggatttagc tcataagtat gggtataaac
    24421 gggtttttac cagtttgctg cagatcaatg atgataaaga aaaagttctt tcagaattta
    24481 aagaagtagt tgattacgcg aatagcctag gcatggaagt aatggttgat atcaatccag
    24541 cgttatttga acagttggag atttcttacg atgacttatc ttttttccat aagatgggtg
    24601 cctacggggt ccgcttagat atcggattca caggagcaga agaagcaaaa atgacgcgca
    24661 atccttttgg tatcaaaatc gagatcaata tgagttcggg cacgaattac gttgacaaca
    24721 tcatgagtta ttcgccaaac acggataatt tattaggttc tcataatttt tatcctcatc
    24781 gatactctgg tttaggatac gaacactttg ttttttgttc agaaaaattc agaaaatata
    24841 atttgaatac gatggcattc gtcaattcgc aatctgctga gtttggccct tggcctacgc
    24901 aagatggctt gtgcacgctg gaagaccacc gagatcttga aattgcgaca caagtgaagc
    24961 atttaatcct tacaggattg attgatgata tttctattgg aaatgcgtac gcaagtgaag
    25021 aagaattgaa agaaatggca gaagcattta acgcggatta tccaacattg aaagtagata
    25081 cggaagaagg tattacagaa aacgaacgaa tctgcttgtt tgataacctt catagttatc
    25141 gaggggatcg ctcagaatat atccttcgtt caacgatgac tcgtgtatac tacaaagata
    25201 aagatttccc gcctcataat acgcgagata tgcatcatgg ggatgtactg attgacaatg
    25261 aagggtacgg tcaatacaaa ggagaaacac aaatcgcctt gaaggatatg aaaaacgacg
    25321 gacgtgtcaa tgttgtagga agaatctccg atgacgaatt attcctcctt gactttttga
    25381 aaccatggtc aagctttaaa ttaattgaaa ataaaaaata gataattagt tattgcagaa
    25441 ataatccgct agaaatagcc agttatttct gcttttttat tttgtttttt tatag
//
LOCUS       DAFENC010000036        24937 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.036, whole genome shotgun sequence.
ACCESSION   DAFENC010000036
VERSION     DAFENC010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24937
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.036"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            168..974
                     /locus_tag="LP493_001950"
     CDS             168..974
                     /locus_tag="LP493_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2134097.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            986..2206
                     /locus_tag="LP493_001951"
     CDS             986..2206
                     /locus_tag="LP493_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2134098.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            2196..3782
                     /locus_tag="LP493_001952"
     CDS             2196..3782
                     /locus_tag="LP493_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBL2134099.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            3821..5959
                     /locus_tag="LP493_001953"
     CDS             3821..5959
                     /locus_tag="LP493_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL2134100.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(6327..7310)
                     /locus_tag="LP493_001954"
     CDS             complement(6327..7310)
                     /locus_tag="LP493_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HBL2134101.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            7688..9079
                     /locus_tag="LP493_001955"
     CDS             7688..9079
                     /locus_tag="LP493_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBL2134102.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            9095..10135
                     /locus_tag="LP493_001956"
     CDS             9095..10135
                     /locus_tag="LP493_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL2134103.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            10154..11239
                     /locus_tag="LP493_001957"
     CDS             10154..11239
                     /locus_tag="LP493_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HBL2134104.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            11272..12234
                     /locus_tag="LP493_001958"
     CDS             11272..12234
                     /locus_tag="LP493_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBL2134105.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQIKHKEFYYKHIDVYQKHDYPRINRNNTTAFKIFR
                     AIINRCLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTELIQMYEQNQQDYLNFKIGM
                     FAPDEKFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTLQTSKLANIHIIDPSMNKW
                     FDERDIDQIKESEKLFVRKVKSDYSDKLLNRIDKEILKVGNIDE"
     gene            12227..13654
                     /locus_tag="LP493_001959"
     CDS             12227..13654
                     /locus_tag="LP493_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HBL2134106.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKEN"
     gene            13656..14726
                     /locus_tag="LP493_001960"
     CDS             13656..14726
                     /locus_tag="LP493_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134107.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYF
                     VYCPELLLYDVKNIKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYG
                     IDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTL
                     LISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLS
                     EEKILLPENWAELRKLVEYGII"
     gene            14713..16134
                     /locus_tag="LP493_001961"
     CDS             14713..16134
                     /locus_tag="LP493_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBL2134108.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTS
                     LLIISLVIYFLKIKNRIIDDYNS"
     gene            16147..17154
                     /locus_tag="LP493_001962"
     CDS             16147..17154
                     /locus_tag="LP493_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBL2134109.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            17166..18170
                     /gene="neuB"
                     /locus_tag="LP493_001963"
     CDS             17166..18170
                     /gene="neuB"
                     /locus_tag="LP493_001963"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HBL2134110.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            18167..19315
                     /gene="neuC"
                     /locus_tag="LP493_001964"
     CDS             18167..19315
                     /gene="neuC"
                     /locus_tag="LP493_001964"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HBL2134111.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            19288..19965
                     /locus_tag="LP493_001965"
     CDS             19288..19965
                     /locus_tag="LP493_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBL2134112.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            19955..21097
                     /locus_tag="LP493_001966"
     CDS             19955..21097
                     /locus_tag="LP493_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBL2134113.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            21110..22087
                     /locus_tag="LP493_001967"
     CDS             21110..22087
                     /locus_tag="LP493_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBL2134114.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            22087..22995
                     /locus_tag="LP493_001968"
     CDS             22087..22995
                     /locus_tag="LP493_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HBL2134115.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            22996..23748
                     /locus_tag="LP493_001969"
     CDS             22996..23748
                     /locus_tag="LP493_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HBL2134116.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            23753..24700
                     /locus_tag="LP493_001970"
     CDS             23753..24700
                     /locus_tag="LP493_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HBL2134117.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT         8766 a         3478 c         4658 g         8035 t
ORIGIN      
        1 ttttttggtt tattgcaatt gtctagcatc ttctgtaaaa tagaaacgtt agagaaaatc
       61 ttgtatcata gaaaattaag aaagaaataa gaacgcagct cggtaccaaa aatatggtaa
      121 aatggcactt gactgtaatt cactgaaaat cgcttggagg aacacaaatg tttaaagatt
      181 tgtatttatt tatgaaggac atttatcaga acagaaaatt attgctacag ttttcgatca
      241 atgacttcaa atcaagatat gcaggatcgt ttttaggaat cttatgggcg tttatcaatc
      301 cgctatttac tgtattgatt tattggctgg tatttggtgt tggactgaaa gcacaaatga
      361 tcgatgcaaa atacccattt atcgtatatt tagttaccgg gatgattccc tggttcttct
      421 tctcagatgc atttgcatca actacggttg tttttcggga atatacttat ttagtaaaga
      481 aagtcgtatt caatattcgt atcttgccca cgacgaaaat cctatccaat ctgtacaccc
      541 acttattctt cattctgatt ggcatagctg tcgcgcttat aaatggtata tatccttcag
      601 caatgtcttt acagctgatt tattatttat tttgcatgtg tgctttcttg acaggattga
      661 cttggctgac ggcatcgatc caaccatttt tacctgatat catgcaatta attacgatcg
      721 tgctgcagtt gatcatgtgg acattaccga tattatggag ccctaatcag tttgattcag
      781 gtcttgtaag catattgaaa ttaaatccgc tgtactatgt tgttcaaggt tatcgtgagt
      841 catttttaag tgaagcttgg ttctgggagc atggaacata tactttgtat ttctgggttt
      901 tcacgttagt aatgttcgta atcggctctg cagtgttccg tagattgaaa ccacattttt
      961 cagatgtgct gtaaggagaa tagctatgac agaatatgca attagactaa aagatatcac
     1021 aaaatcttat aatatgtacg caaaaccttc ggatcgattt cgtgaagccc tcaatccttt
     1081 taagaaatcc tatcatgatg tattttatgc gttgaaaaac gtgaatgtag aaataaaaaa
     1141 aggtgagatg atcggtttcg tgggagaaaa cggatcggga aaatctacaa tgttgaaaat
     1201 cattacggga gtactgacac caacatccgg cacgatggaa atcgaaggaa aaatctcagc
     1261 tttgctagaa ctaggatcag gattcaatcc tgagtattct ggctatgaaa atatctattt
     1321 aaatggaatg gttctaggat tttcaagaga agaagtcgat gaaatggtcg atgatatcat
     1381 tgaatttgct gacatcggag accatattta tcaacctgta aaaacttatt caagcgggat
     1441 gttcgttcgt ctagcttttg ctgtagcaat caatgtgaat cccgatattt tgattgtgga
     1501 tgaagcattg gcagtaggcg atcttgaatt tcaactaaaa tgtatggaaa aatttacaga
     1561 aatcaagaac tcgggaaaga cgattttatt cgtttctcat gatatcagtt cgattcgtcg
     1621 tttttgtgat cgttcctatt ggttgaaaaa cggagaagtc gtcgaatatg gcgatacgat
     1681 ggaagtaacg acgaattatg aaaacttttt aaagaaaaaa tcagttaaaa cagtggatcg
     1741 gaataaaaac caagtagaac ggttcgccgc tccagatatc gtcgacgtga cgaaagcgga
     1801 attgttggat aaagacaaaa atccggtgga tatgctggaa caaggagaaa aactatacgt
     1861 taaagtaact tatgaagtaa aagatgatac aatcaaaaat ccggttttag gaattgcgct
     1921 acgaacagtc gacaattttt atgtatgcgg acttaatact ctactagatg gtatcaagat
     1981 tccttggaaa aaaggagaga atatctttta tctggagtat gaaaagttag gtttgttagc
     2041 tggtgaatat tattttgacg ttgcggtctt tgaagaaaat gcaacggttc ctttggtata
     2101 taagacaaag tacatgaact tgtttgtcag cggttcttat atcggagaag gcatcgtggt
     2161 cttagaccat aaatgggaag aagggactca tagcaatgaa atatgatttt gaaatggacc
     2221 tagatgaaca aagcagtgtg ggaaaaattg ccgcacagat caaaccagga agtaaagttt
     2281 tagagtttgg tcccggaaac ggccgattaa cgaaacattt aatcggagca aaacaatgtg
     2341 aagtgagcat tgttgagtta gataaggaat tgttcgattt tgtcagcgaa tttgctcaag
     2401 atggatttta tggtgatatc gaaagttttg agtgggcaaa ctattatgct ggacagacat
     2461 ttgattacgt cttgtttgcg gatgttttag aacatttggt agatcctgga aaaacattga
     2521 agaaagtcag agaatttttg aatgaagaag gagagatcct gattacattc cctaacttgg
     2581 cgcataattc tgtcatgatc gatttgttca ataaccaatt gccgtgggct tcttatggtc
     2641 tcctagatga aacccataat tctttttata ctcatgatgg cttccaaaaa gtttttgaaa
     2701 aagcgggatt attcattaat attgaagatt atttgtactt agctgtaggt gatacagaat
     2761 taaaatcaac ttatgaagaa ttgccggaag ctgtacgcta tgatttcaaa atgcgaccat
     2821 ttggtgaagt ctaccaatac tttttctcat tgatgaaaca tccagtagca caaagttcca
     2881 ttgcagagcc acaaaattct aattatgtaa aagtgttaga agtaacccag caaacgaaac
     2941 aagatgaaac aatccaacaa ataccattca ataatttcac aggggaaaat gagacactaa
     3001 gtttccccgt atcagaaaca acagaaagaa tggtgtttcg cttcgcgcaa caacctagct
     3061 ttatcgaatt cagcgcagaa gctgccggag aaaaactaac atttatcgat tcgaatgctg
     3121 tagtcaaaac agtaaatgat tgttatttgt ttgatgggaa agaattacca gagttcgttc
     3181 taacggatat ttctgggaaa gaagtgacta tccattgtca ctatcgcttt atcggggaat
     3241 tgacaccaac aatgaaagaa ttgttggaaa cgattcgtcc catggctgaa gtcacaaagc
     3301 agctttctga gaaaaatgac gaattagaaa gagaaaatca tcatcttctt gaggaaaata
     3361 caagactaga ccatacgtta aaaacaacca caaatcgcta ttgcacattg ttggaaagtg
     3421 atgaatggac aataaaacat agactaggac gacgtaagaa agaaacttcg aaaaaaatcc
     3481 aagaaaaaga actttctata tgtattgacg agaaaatctg ggatgcagaa acaaaaatat
     3541 taaaaatcat cggatgggga atcgctaatt cggatcgcca gcccttgtcc tataagttat
     3601 cagctgacca atcgccattt ttcgaagcaa ttcctgtttc acgagaagaa gtcaatcaag
     3661 cagaacagct cgcaaaagga acagaagcgg gatttgagtt acgaatcctt tgcgagcaag
     3721 aacgttcatt cttagtggaa gcagtagctc aaaatggcca atcatggatc attgaaatgt
     3781 aaataatgat taacttataa agataaggag taaacgaatc gtgcaaaaaa aagaaattgc
     3841 cgtatttatc gatcaaatca ctcgtgaacg ggccactggc gatttgctta ttgtgggctg
     3901 ggcaattgat gaagtgacca aagaaatccc tacgataaag gtagaaaaag aaaatgtgat
     3961 tgctgaagca acacatgtcg taagattgga tatcaatcat ttatataatc ttgatgttaa
     4021 gacccaaagc ggttttaagg tacgtttatc agggaaaatg agaggaaaag ccatcttaga
     4081 cttccaaaca gcgagacatc aaaatggcat agctgtgaaa ttaaacggta aataccctta
     4141 tgatgacggc attgaatctt catgggaaag aaaaaaaaga ttactgaaaa aagggataaa
     4201 ttatgcaagg actcatggcg taaaaaaagc gatccgtcgg gtcaaattgg aattgaagcc
     4261 aggatcgatc gactatgcag agtggatcag tcgtcatgag aaaccagatt tgaaagagca
     4321 aaggaaagaa gcacaaggat ttgcgtaccg tccattgatt tccatactta tgcctgtcta
     4381 taacgttgaa atcaaatggc tcgaaaaatg cattgattcg gtactggatc aaacgtatga
     4441 tcattgggaa ctatgtatca gtgatgatgc ttctactgat ccagctatcc gaaagtgtct
     4501 ggaatcctat caagcaaaag atgatagaat caaagtcgtt ttccgaaaag aaaatggaca
     4561 catcagtctg gcaactaatt ctgcattgga aatagcagaa ggagaattta tagcactctt
     4621 agataatgat gatgaattac cgccatttgc attatatgaa gtggcaaaag tgctaaacgt
     4681 acatccagaa ctggatgtga tctacagtga cgaagataaa atcgatgcag atggcaatcg
     4741 ctttgatccg catttcaaag cagactggtc gcctgataca ttgatgggaa ataattatat
     4801 ctctcactta ggcgtatatc gaacaagcat tgttaaagaa cttggcggtt tccgtaaagg
     4861 ctatgaaggt tctcaagatt atgatttggt ccttcgtgtg acagaacaaa tccctgcaga
     4921 tcatatttac cacattgacc gagtcttgta tcattggcgg acgatcccag gatcaactgc
     4981 aagtaatggc gaagccaaaa gttatatcta tgattccgga gtgaaagcat tgacagatgc
     5041 cctgtctaga agaaacatca aaggaagcgt acgtcctggc agaatttctg gattttatga
     5101 gattgcttat gacgtcttgc aagaggattt ggtcagtgtg atcattccaa cgaagaatgg
     5161 ctatgaagat ctaaaaactt gtgtggattc gatcatcgaa aaaacgtctt attcaaatta
     5221 tgaaatcatt attgcggata acggaagtac agatccaaaa atgcaagaat tatttgcaga
     5281 atacaagcat cagctgaaag accgctttat cgtagaattg attgacattc cattcaatta
     5341 ttctcgaatt aacaatttag cagcagaaaa agcaaacggc aaatactttt tattcttgaa
     5401 taacgataca gaagtgattg agccagattg gatgacggtg atggtttctt atgcacagtt
     5461 tgatcgaatc ggctgtgtag gagcaaaact gttttatcca gatgatacaa cgcagcatgc
     5521 aggagtatta ttaggaatcg gtggtgttgc agggcatgca ttgaataact atgatcgaac
     5581 acattgtggt tatttcggcc gattggtcat tgacgtcaat tacttagcag tcactgcagc
     5641 ttgtatgatg gtcaaggcag ctgacttcaa tgctgttaac gggtttgatg aaacattaga
     5701 agtagcattc aacgatgttg acttgtgctt gaaagtttat gaactgggtc gttacaatgt
     5761 ctatgcacat caagcagaat tgtaccattt cgaatctaaa tcaagaggtt atgaagatac
     5821 tccagaaaaa caaagacgtt ttgctggtga aatcaaaaaa atgcaagata aatggccagc
     5881 atatattgcg catgatccat tttacaatga taatttaaca aaagaaggaa tcggcgactt
     5941 ttcgttgaga ccagattaaa ctataataaa aagctgttat gttgtgattc gctcgcacat
     6001 aacggctttt tatagttttt tgtcaaaaaa aggcagaagg tgccgactca aaaaaataag
     6061 tcgaggttgg gacagaagtg tttaactccg agaaataaga agaaattcac gaaaattgct
     6121 tttcaaattt ttgtgaattt cggcttattt aagaagaagt tgcttctgct cccaccgttt
     6181 attcgttttt aaagaatgag acaaaagtgt ttcttacttt tgtcccacgc tcttattcat
     6241 gctcagagcg ccaatagata caaaatcata gccaaagttt cacgaaccct agctgtcaaa
     6301 gaatcgatat tttattttaa tataggctat tttaaaataa atggtttaag gtattcctct
     6361 acaaaagcca ctctatcaat tatcatgggt ttaaaataag aagtgatgga gataaccaga
     6421 ttgttcttag cgtcaatata aagaacattt ccactattac caattgctga atatatttcg
     6481 ttctcagaat ctaataccca ccataaatag ccatatctca tattttgtaa gtcttctaaa
     6541 gcactggttc taggtttgaa catctcgttt atccacatgg gtggtacgat ttgttttcct
     6601 ttatacatcc ctttatttag gcataataca ccaatttttg ccagatcact tgccgataaa
     6661 cacaaaccat atcctgccgt cccgatattt agtggatcac aaaaccagac attggtttta
     6721 ggagacttat ccattgtaaa ctgcttatgt tcttcagctg tttcagcata ataattgaca
     6781 tggtttggta tccctatagg atcaaataga tacttattgg caaaatcaac agttgttagc
     6841 ttacttgtct gatacaacaa gccagttaat atgtgtaaac agacagtttg atagttgaat
     6901 tcgccggtta taccttttct tcctcccaat aaatctagtg atgtttttgt ccaatcttca
     6961 cttgaacaga cttttgtcca tggatcgcct ttacatttgt agggtgcttt cattgttagc
     7021 aagtgcttga ttgtaatagc gtaaatagtt ttctccccgc gtttcacttt atactctgga
     7081 aaataatcta atactttatc atcgatactt ttgattaatc cttgctctaa agcaatgcca
     7141 atcagcaaag atacaatact tttcgttgct gacatgatat gacaagtatc gtctttttta
     7201 taaccattcc attcatctgt ataaacttct accccatcct tatatgcgac aatttgacat
     7261 atatttggtt gtcgaaaacc aataaaatca tgcaactctt gtttattcat aagatattac
     7321 ctcactttct tctataagca taatgtcatt aaaaatcgat ttcaattttt tcgattcttc
     7381 acgtaataca ggtattctta tggactagac agcgctttgg gaagatggat tctctgaaaa
     7441 atataaaggt tcactttatg agtggataaa aaaagcagca aatacttcga cttctttaat
     7501 ttaccaacat tagtgaaaat cgattcatct ggagatttgt aatttagagt ccttgtcttg
     7561 attagaggtg tataaagctt tttattagac atttttaaat tccattacaa tttgcttata
     7621 aactaggttt ttaaaggtga ctatggtaag ataatagaga tattattttg tgattaggag
     7681 tgtatatatg aataaaaatg gagaatggag tgctgcacga cggatattca ttatattaat
     7741 ggatgttatt gtatacaatg cagcaatata tagtagtttc ttactgaagt ttcgtggaga
     7801 gatcccatta cgaaatttag aaactttcca acactcagca attattattt cagtgatttt
     7861 tattgcgttg aacattttgt tgggtgcata tgttttttat aatcgaatga tcagtgacat
     7921 cgtgtttgtc acagtcatcg gtcaggtatt gatgacacta gggatcatgg tagtgacttt
     7981 tgcgggccgc tggtttgctt ttccacgtct tgttatctta ctttcatttg ttctcggtac
     8041 gcttttctta agtatctatc gtattctcgt atataaactt tatttacgcg taagtcgaga
     8101 taaaaaggtc gtcattattg ggttagaaaa ggatgtcgca ccagcaatcc aaaattttgg
     8161 ttcaaagaaa aacaacaaac ataaagtcga agcagtcatt cttgataact attatgcaaa
     8221 catcaaaaat atgattaaag acatcgatat tgtctatctt gcttctcata tcgaagaaac
     8281 tgaaaaaatc aaaatctatc aattagttac taaaaatgaa aaaaaattgt ttttgaatac
     8341 aacatttgaa aacttgacat tgatcaatcc aaatattatg aatttcgaag atgaaagtat
     8401 tattgaagca tctggattta gaatccaacc tgaatatgaa ctattcaaac gtttgtttga
     8461 tatcatcgtt tcacttgttt tattagttat tgcttcacca tttatgttat tcacagcaat
     8521 tttagtcaaa gtgacatcac cgggaccaat catctataaa caagtgcgga tcacaaaaaa
     8581 tcaaaaggaa ttttcaatct ataaattccg ctcgatgacc gccacagccg aagcaaaatc
     8641 tggaccagtt ttagctaaga gcaatgatgc acgagtaacg cctgtaggta aatttattcg
     8701 agctgtccgc tttgatgaat taccacaaat cttcaatgtg ctgaaaggcg atatgtcgat
     8761 cgtaggacca cgtcctgaac gtcctttctt cgtcgatcag ttcaatgcag aaaaccctta
     8821 ttactactta cggcataatg ttcgtgctgg tatcactggg tatgcacaag tctatggaaa
     8881 atatgtctct gattacaaca gtaaattacg ttttgattta ctttatatca aaaaatattc
     8941 attgatgctt gatttaaaga tcttgctgca aaccatcaag atcctatttg ataaaatgtc
     9001 ctctcaagga cttgaagaag acgaaaatgt gatctcattg gcagaaattg cttttccgaa
     9061 tgaaaaaatc tttcgctagt tgggaggcgt aaaaatgaac aatccgaaat tcagcataat
     9121 cgtaccagta tacaatgcag aagcaactat tggtcgaacg attgatattc taaaagaatt
     9181 ggattatgaa gagtacgaag tcgttttagt aaatgatgga tcaacagatc aaacacagga
     9241 aatcattcaa gaactgattg aaaatgatga acgttttgaa ttgattacta cgaccaatca
     9301 agggcccgga ttagcaagaa acgaaggaat aagacagtca aaaggagaat atctcttatt
     9361 cttcgatgca gatgacacgc cagtaaaaac gatcttgtca gattatgatc atttgctaga
     9421 aaagagtcca aaagcggatc ttgttgttag ttcgtttgtt tttcgtacaa tggacgaggg
     9481 aagaatcgtt tccgaaaaag aaaacttagt tacagaatgt cactatctaa ctcacgaaga
     9541 gtttataaaa gacatgtatc agttaatgaa tgaacagttg atgtatgttg tatggaacaa
     9601 atgctatcgt agcgatattc tgaaaaataa ccaaattcta tttaaaactt ataatagttg
     9661 tgaggatcga atatttaact tacattatta tgaatactgt catcaagtga tcatgaaccc
     9721 aaaagtagaa tatatttatg aatttgaagg tgggaagggg atcactaatc aataccgacc
     9781 taacaagttc gaaacattta aagaattcta ttcattagca aatactgtaa cagacgatat
     9841 taataaagac ggtatggcgg cgcttctttt aaaagggaca acttcagtta ttttttctat
     9901 ttatagtacc tctgcaagaa cttcaaaaga gaagaaagac gaagcaaagc agatattgag
     9961 tgatccagtg atccgagaag ccaagcaaat tgctaagacg gattcttcag caaaaaaaat
    10021 aacaaagttg ctttacaata tgccagctcc actattttta tctgctgtaa aagttggaag
    10081 cttcgttgaa gtgaaaatgc cagggttaat ggctgctttg aagcgagtat attagttaat
    10141 ggaggaaaat ataatgaaaa gaattttgca ttttcaggga cgaatgggtt taggtggagc
    10201 agagtctttc atgatgaatt tatatcgtaa aattgatcgt acaaactatc aatttgattt
    10261 tttgatttat gaagattatg cagatgttca agactatcat tcagagattg aaagattagg
    10321 aggccgtatt tttgttgtac ctaatcctaa gaaaaatatt tttaaatatt taatagaagt
    10381 gaataagtta ctaaaaaaag aatctttttc tatagttcac aatcaggttt attttggcgg
    10441 gggaattaat ttatggttag ccaaaaagaa tggaatcaga cagagaattg ctcatagcca
    10501 tgcaactgaa gatggaaaat ctcaaaatat tgtaatgaat gtattgcgta aatttttaac
    10561 caaattgttg ttacaaaatg caacagacta ccttgccgtt agtcaagaag ctggtgaaag
    10621 tctgtttcaa aaccacccct ttgagatagt tcataatggt attgatttag agctttatag
    10681 taaaaattca gaagctaagg ttaataagag aaaagaattg gatatctcaa tgagtacttt
    10741 tgttgtggga aacattggac gattagagaa acaaaaaaat caatcttatt tgttagagat
    10801 ttttttagaa atactaaaaa tgaattctga ttcttacttg attttagtag gtgaagggtc
    10861 acttagaaat aaactgaaag ccaaagcagt agaattggat atagagaaaa gagtaaaatt
    10921 tttaggagaa agaaacgata ttcccgagtt attatctgtg atggatgttt ttgtaatgcc
    10981 ttctctttat gaaggtctgc caatggttgg attagaagca caagcagcaa aattaaaatt
    11041 agtcttagca gatactattt ccaaagatac aaagttaaca aataatgtgg attttgtatc
    11101 attagatgaa acaccacaag aatgggcaaa aaaagtaata aaagagccgt atgctaataa
    11161 aataacacaa gaactaaaga gttatgatgt ttcgtacact actgaacaaa tggagagtat
    11221 atatagtaga gatcattaaa aatgttcaag atattttagg agtgattatt tttgaaaata
    11281 tgttatttga tattggcata caatgatatt ggcaacttaa agagattggt caatcgattg
    11341 aacgaaaatg cagtttttat tattcatata gataaaaaaa ctgatataga accatttatt
    11401 gaagcattta aatcatatga taatgttgaa tttttatgta ataaaaaccg tgttaaaatt
    11461 tattggggtg gtttttccat tgtacaagca gaaatcaatt tagtaaagag agcattacaa
    11521 aatgagaaat atttaaaata tgtattatta tctggtgctg attatccaat caaagataat
    11581 gagtatattt ataattattt taaaaagaat agttcagtgg agtttattcg tggaatagat
    11641 ctagatcaaa ttaaacataa agaattttat tataaacata tagatgtata tcaaaaacat
    11701 gattatccta gaattaatag gaataacaca actgcattta aaatttttag agctataatt
    11761 aatcgttgtc tgaggatgat taaacttccc ccaaaaatta gacaccataa atttgatttg
    11821 tatcatggtt ctcaatggtg ggctttgtcg aaagaatgcc taacagaatt aatacaaatg
    11881 tatgaacaaa atcaacaaga ctacctgaat tttaaaatag gtatgtttgc cccagatgaa
    11941 aaattttttc atacactttt ttttaattcc tcgttcaaaa ataaaaatgt tattggagga
    12001 ccagatttac cacttgaatt gaaaaatatt gaagaaacta ctttacaaac ttcgaaatta
    12061 gcaaatattc atattattga tccttccatg aacaaatggt ttgatgaaag ggatatagat
    12121 caaataaaag aaagtgaaaa attatttgta agaaaagtta aatcggatta ctctgataaa
    12181 ctattaaata gaattgataa agaaattttg aaagttggaa atatagatga atagaatagt
    12241 acctgtttta gagaagagtt tattaagtcg agatgcgttt cgagtaataa atttaatcat
    12301 ttgtctgctt tattttatgc ctagtacttt taatgtaact aatatcccga tgaaaatagc
    12361 ttttgcttgg ggtggaatta tagttttgta tgaggttttt ataaagaaaa atttttttaa
    12421 aatgcgtttt tcttggctac tgattggagc aatgattagt tttatcttaa ctataatcat
    12481 taacagagaa aattttttaa ttccatctat ttataatttt ggatatttgc tgattacttt
    12541 gatagtaatt tttcctgcag acttttcaca aagtgaagag gaaaaaaaga aaaaaatggt
    12601 gtattttaat aatgttttca ttatcataat ttttttagct gcgctaatat ctatctatca
    12661 atttattttt ttgatttctt atcatgtccc aacaggaacg ccaggattac ttgcaagaca
    12721 aggttttatt gaacatcggt tatttggtgt ctatacaagt ccaaatgttg gagctatgtt
    12781 tggatatact tctattattt taagtttaat tagtgtatta atttcaaaaa taacaaaaac
    12841 gattcgtgtt ttttatatga tgaattttat cgtacaaata ttttatatta cactttcttc
    12901 gtctagaggt gcccaggtag taatttgttc ttttttagta ttatttcttt tgttgtttgc
    12961 caattcaaaa tttagaaaga gcattagaga agtactacct gtaaaaatca aatggatggt
    13021 aagcatatta ttagttctat tggtatattt ttcttttggt actaattatg ctaaggattt
    13081 tttagcaaca attcctgtat cgattgatag aaaagtagaa gttatagagt caaatgaatc
    13141 agataaaact ccacttccag aaaaagaagt aatattacag cattctagtg ataactccga
    13201 aatttcagct ggtcgtttta cgatttggaa agctgcgctt aaagttataa gaccaacttt
    13261 gttatttggt tatggagaga ccgatttcta tgggaatagc gatgcaaaat ttttgaaaaa
    13321 agtagatctt gatactacag atgtgaatga actaaaaaga gcacatggaa acatgcataa
    13381 tggatttctt caagtacttg tatcaagtgg tataattgct tttatatgta tctatgcttt
    13441 ctatgtgtta aatatcttta gtttactcaa aacatttttt agaagtaaag tgaattatgc
    13501 gtttcttggt attgttttaa tttttatact atctattttt atagatgaaa tggtggaggc
    13561 tcatgtactt ttcaataagc gcgatgtcat ttcaattgtt ttctggtatt atttgggaag
    13621 catttcttac ttgtatttaa aaaaggagaa ttaatatgaa gacagctttc attgcttgga
    13681 ctcctttaca tttgattaat atattaaatg tttatcaaaa tttttaccga gaatcaaaag
    13741 gagatttatt tatttattct gaatttgaaa acgctagaag atatagtgag cgtataaaag
    13801 aattagggct atttaatgat gttgtttttg tgaatcaccg gaaaatcggt tcttccttta
    13861 aacgtaaaat taacttgtta actaaccata atcaattttt ctcggatgat ttatccgttt
    13921 atgatgaaat ttttatacag ggggaaaatt atttcacaaa aatacttttc tccaatgttt
    13981 acaaaaaaaa tccagatgta aaactaaatt atatagaaga tggtttgggt acttatttga
    14041 agaagagtat attttcaaca agtaaaaacg ttcaaagagt ttttaaaata ttaaataaaa
    14101 atagcatctt caaaaaaaaa attgacgatt attttgtcta ttgtccggaa ttgttacttt
    14161 atgatgtaaa aaatataaaa aaaattccca aaatagatga aaacagtaaa ttgatgaaaa
    14221 acatacaatc aatctttggg atagaagaag tttttgtcgg agataaatgt atcttttttg
    14281 atcaaccttt attatctgat ggttatggca tagatgaaac agatattttc gctaaagtaa
    14341 atagtatatt ttctggaaaa aaagaaactt taattaagct tcatcctaga gcaaggacaa
    14401 atcgttatgg tgaaaaaaac atattgaatt ccagtttacc gtttgaagtc ttgctacttg
    14461 aaaatgactt ctcttcaaca cttttgatta gtcctatatc tacaatttct ttttcaccat
    14521 ctatgatgtt tgaaaagacg atcaactcta ttatgttggc taaattaatt ttaaatgaat
    14581 atacagcatt atctgaagat aaaaaagaaa cattgacaaa tattgttctt ttctgtgaac
    14641 attataaccg tctatcagaa gaaaaaattt tactcccaga aaactgggca gaattaagaa
    14701 agttggtaga gtatgggatt atttaacaca ctttccaagt caaaattagt taagtccagt
    14761 ttctggtata ctatagggaa tttttttatt aagggaattt cattcataac tattcctatt
    14821 tttgtaaata ttactactca agcagaatat ggtttgatta ataatttcac ttcatttgta
    14881 tcaatttttt cgattcttgt tgggctaagc ctaaattcgg caattaataa tgcaagtttt
    14941 gactataaag atgacataaa tgaatttatg tcatcggtac tttctctagc tacactttcg
    15001 ttaattgtgt tcttattaat agggaacata tattttttgt tttcaaatgc tttttttgat
    15061 atgaaccaac ttgtatttaa tttgatgtta ttacaaagtt ttgctagttt tgtaattagt
    15121 tatatccagt cttattttac gattaacttt aaccatttta aatatttgat tttatctttt
    15181 atatctactt ttttgaatat tgcaatctct gtagctttga tgcagacatt atattttgat
    15241 gataaatatg ttggcagagt agtcggcgga acactgtcat ttgtgttgat aggtttagta
    15301 atttatttaa gaataatgat aaagggtgct catttttttg ataaaaaaca gtggagatac
    15361 gctttaaaaa tctctttgcc gctaatccca cattccttag caaatatagt tttagcacaa
    15421 ttcgatagaa ttatgattaa ttcttattta ggtcctgctg cggggggaat atattcctac
    15481 attagtaaca taggtattat tctaagcgta atatggatgt ctactaataa cgcctgggtt
    15541 ccatggttct atggtgagat gagtaaaaat aatgaaaaaa aagtgaagaa agttagtaac
    15601 tattatttag tagtctttac tttgattacg atgattgtaa tggtagtttc gattgattta
    15661 gcaaaattta tggctccgaa agactattat tctgggttat ctttagtggt tccgataacc
    15721 ttaggctatt tctttcagtt tttatatagt ttaccagtta atgctgaatt ttatgagaaa
    15781 aaaacatcgt ttattgcgat tggtacagta gcaagtgcta tagttaatat actattaaac
    15841 atgattttca tacctaggtt aggaataatt gctgctggat acacaaccgt atttacgtat
    15901 tttttacttt ttatttttca ttataatatc gctaaaaaaa ttacgaataa acaattattt
    15961 gacacaaaaa aaatatgtat cataataatt tttgtatcaa ttttttcttt gatacttcat
    16021 attttaatca atcaaatgtt gattcgttac gttttgacat cattattgat aattagttta
    16081 gttatatatt ttttaaagat taagaatcga attatagatg actataattc ataggaggag
    16141 atataagtgt ttaaaggaaa aacaatatta gtaactggcg gaactggttc cattggaagt
    16201 gaaattgttc gtcagctttt aaaatatgaa ccaaaagcta tcagaattta tagtagaggt
    16261 gaagaaaaac aattttatat gcaacaagag ctctcaaatc acactaattt gagattttta
    16321 attggtgata tcagagactc tcaaaggatt gattatgcat gtcgtgatgt ggatattatt
    16381 tttcatgctg ccgcaatgaa acacgttcca gcaagtgaat ataatcctat ggaagctgta
    16441 aaaacaaatg tgatgggaac tcaaaatgta atagatgcag cgatcaaaaa taatgtaaaa
    16501 cattttgtag gtatcagtac agataaagta gtgagtccta ctaacaccat gggtgcgaca
    16561 aagttattga gtgaaaaatt aataatagct gccaatcagt ataaaggaaa aacagaaaca
    16621 atattttctt gtgtaaggtt tggaaatgtc atggggtcaa gtggatctgt tattcctctt
    16681 tttagtaaac aaataaaaaa caataaagat attactttga cagatgttga tatgacacga
    16741 tttatgatgt caataccgga tgctgcaaga ttagttctgt ctgctgctat gaattcaaaa
    16801 tttggagaaa catatgtctt aaaaatgccg gcaatcaata ttttaacttt agctcaatca
    16861 ttaataaaaa tatataatga tacacatgat gaaaaatata gaggtgaaat aaaagttgta
    16921 ggtatcaggc caggagaaaa attatatgaa gagctaatga ctacagacga aattgaacgc
    16981 tcatatgaaa atgataaaat gtatatcatt ccaccacact atcatgctac tgacgaactg
    17041 tacaaagatt atgaaaaaat taaaatcact gcatactctt cagatgcaac agaattaatg
    17101 agtggacagg aatttattag aatcgcaaaa gagaataatg tcgtgacttg gtaaggagtt
    17161 ttatgatgaa atcagaagta tatgtaattg cagaaattgg tgtaaaccat aatggaagtc
    17221 tagatttagc tttagaaagt attgataaag ctaaagaatg tggagctaac gcggttaaat
    17281 ttcaaacatt taaaacgaat aagctagttt ccaaaaaggc tccaatggca aaatatcaga
    17341 aggataatct taaagaggac agttctcaat ttgaaatgct aaaaaaatta gaattatctc
    17401 aatctgattt tattagaata aaagattatt gtatacaaaa taaaattgat tttttgtcta
    17461 ctccttttga tgaagaaagt gcagactttc taaaacaaat tggtgtacaa ggatttaaaa
    17521 ttggctcagg agatttaaca aatttacctt ttcttagaaa aatagatatg tatgggttgc
    17581 cagttttatt atctacaggt atggctgata ttcatgaggt cagtgaggct gtagattgtt
    17641 tcatagatag tccagttact attttacatt gtacttcaaa ttatccggct agttctgaag
    17701 atattaattt attggcgatt aacacattaa aagaaatgtt cgggataccc gttgggtact
    17761 ccgatcattc attgggatat gatgttggta tttgtgctgt tgcgatgggt gctaaggtaa
    17821 ttgagaaaca ttttaccttg gataaggaac tacctggtcc agatcataaa gcttctttag
    17881 atcctcagga atttgcagat tttgtaaagc atattagaaa cactgaaata tttttaggtg
    17941 atggtgttaa gcgagcaatg ccttctgaac ttagtacaaa agaagtatca agaaaaagcc
    18001 tagtggtcac tgagaattta aatgtgggag atattcttac agagaaatct cttacaataa
    18061 aacgtcctgg aaatggaata gctcctaagt ttttatatca atatattggc aaaaaagtta
    18121 aaagaccaat aagtgcagat agtgttctgc ttgaggaaga tgttgaatga aaaaaatact
    18181 tatagtaagt ggaacacgag ctgattatgg aatatataaa cctgttgctg agaatttact
    18241 acaagataat tgggatgtat catttgttgt ttctggaatg catttatccc ataaatatgg
    18301 atttactaaa gaattgatct tagctgacgg atttagaatt agtggagaag ttcaaagttt
    18361 gtttttagag aacaataagg gaaacatggc tcggtctgtg gcattagaga taaatggttt
    18421 cacaaatata tttgaacaaa ctagccctga ttttgtatta ttactagggg atagaggaga
    18481 aatgttggca gctgcgatag cttgtttgta tcttggaatc aaaacagcac atattcacgg
    18541 aggcgaagtg tctggtactg tagatgaatc aataagacat gccataacga aaatagcatc
    18601 tgttcatttt gctgctacgg aaaaaagcaa agagcgttta ataaaaatgg gggaagattc
    18661 ttggagagtt tttcccgtcg gagctcctag aatagatact attttaaata atagattacc
    18721 tagttttaga gatataaaag aaaaatatca tctaaaattt gaaaagaaaa aatacgtttt
    18781 gcaagtattt catccagttg taaccgaact agaaaatata gaaaaacaaa ttttagcttt
    18841 gatcaattca atggaacaac aatctcaacc aattatttgc attttaccta atagtgatgc
    18901 tggtagcgaa attatcagaa aaatgtacca gaaatattta aaaacggata ttatttatat
    18961 tacgaattta gagccggagg aatacctgac tatattaaaa gagtgcaaat ttatgatcgg
    19021 aaattcttct tctgggataa ttgaagctgc atcattcaaa ataccagtaa taaatttagg
    19081 aaccagacaa aatggacgag aacaatctaa aaatattata aatgcaaatc taaatgaaaa
    19141 tgaaattgaa actgctttga ataaaataca agatcctcag tttataaaaa gcttgaaaaa
    19201 tgttaagaac atctacggtg acggcaacag ttctagaaga ataacaaaaa cattgaatca
    19261 aatattgaat gatggggaag atattaagtg gattcaaaaa caaatagctt attaaaatat
    19321 actagtgatc catacattat tattggggct ggcggacacg caaaagtcat tattgaaacc
    19381 ttaagattag aaaataagtt aatatatgga ttttttgatg ataagcaaaa taaaatgcaa
    19441 gatctgaaat atcttgggaa aataaacgaa ttgaatagct gggcggatag caaaaaaaaa
    19501 atctataaat ttattgtagc tattggtgac tgtgtagtaa gaaaaaagat tataaaaaaa
    19561 ttgaatatgc caagtgagca atatggaata gctgttcatc caagtgctat agtggcaaaa
    19621 gaaatttcaa ttggttatgg aactgttatt tttgcgaatg ctgtaattaa cccagatgct
    19681 gtaattggag agcatgctat aataaacaca ggtagcattg ttgagcatga ttgtagaatt
    19741 aataactatg ttcatttatc tccaggtgta tgcttagcgg gtggagtaca tgtaggtgta
    19801 ggaactcaaa taggaattgg ttctcaatgt atccagatga agaaaattgg atcttggtgt
    19861 atgataggcg cagggagcac tattgttaag gatattccct cacattcctt agcttatggc
    19921 aatccagcta aaattaagaa agaaggaatt aattttgaat tctagaattt tattatcaag
    19981 tcctcatatg ggaggaacag aagaaaaata tgttgctaag gcttttaaag ataattggat
    20041 agcgccatta ggtgaaaatg tggataaatt tgaagaaagt attacaaaat atactggttc
    20101 taagggcgga gcttctgcgt taagttcagg tacagctgcc atacatcttg ccttaagact
    20161 gcttaatgtt ggaaaaaacg atattgtctt tgctccttca tttactttta tagctacagt
    20221 aaatcctatt ttatatcaag gggctgtacc agtgttcatt gactcagaac ctaatacatg
    20281 gaatatgagc cctgttgcac tagagagcgc attagaagaa gctgaaagaa acaaccaatt
    20341 acctaaggca atcatcgtag tgaatttata tggtcaaatg gctgattatg aacgaatttt
    20401 agctattgca aaccaattta atgttccagt gatagaagat gcagcggaat cgttaggttc
    20461 tacttataag ggaatttcgt caggcttatt tgggacaatt gggatctatt catttaacgg
    20521 taataagatc atcacaacct caggtggagg agctctagtg tctagtgata aaaaatatgt
    20581 tgagcattca agatttttag caacacaagc aagagatcaa gcaccgtatt atcaacatag
    20641 cgaaataggt tataattacc gtctaagcaa tatttctgcc ggtatcggac gtggacaaat
    20701 ggaagtattg aatgatagag tagctaaacg aagagaaatt ttcaatcgat ataaggaagc
    20761 tttttctgga attgatagaa ttgaaatgat gccagaagtg gatggcatgg tgccaaatcg
    20821 ttggttgtct actttaacga tcaatgatta taattctatt gatcaagtag ttaacgtaat
    20881 aaataaacta aatgaaaaaa acattgaaac aagagctttg tggaaaccac tacatttgca
    20941 accagtattt caaggggtaa aaatgtatta ccatgataat aatcttagtg tgtcagaaaa
    21001 gttatttaat agcggcttat gcttaccttc tggaagtaat atgacagata gtgaacaaga
    21061 atttgttatt gatgagttta aaaaaatatt caagtaggtg tgatatttta tgaacatagg
    21121 aattattggt ttaggttcca tggggaaaag aagacttaga ctcattcaag aacactttaa
    21181 tgatatttta ctatgtggtg ttgatactaa tgaggcgaga cgaaaggaag ttgaaaagga
    21241 atttggaata ccaacttata atagtctaac agaggcaaaa aatttgtttg aaataaattc
    21301 agtttttgtt tgtacatccc ctataaccca tgaatttatt ataaaagagg ctttaaattt
    21361 agattgtaat atctttacgg aaatcaattt attaaatgaa tattatgatg aaataatcga
    21421 agtagctaaa aagaaagata gattacttta tctatcttct acatttttga agagaaaaga
    21481 aattcaatat attaagtcta aagtgacgca taataaaaaa atttcttatc aataccatgt
    21541 aggacagtat ttacccgact ggcatccttg ggaagattat cgcaattttt ttgtttcaaa
    21601 caaaaaaact aatgggtgta gagaaatatt cgctattgaa ttaccttgga ttatagatac
    21661 atttgggaaa gttaaatcgt ttactgtaat gacccagaaa ttatccaatc ttgatattga
    21721 ttattcggac agtttcactc ttattattga gcatgaaact ggtatagttg gaactttaag
    21781 tgtagatgtt gtttcaagag tagctaaaag aaatttaact ataattggtg aaaagatttt
    21841 aatagaatgg gaaggtaacc cggattctct attttcatgg aatgaagaaa cttctagtat
    21901 gacagatatt caattgtacg atgaggttat gcatgataat aattattcac atactattat
    21961 tgaagatgca tatttagagg agattaaaga atttttcacg cttttggaaa agaaaatgga
    22021 accccaatat acttttgaaa aagataagta tattattaac ttaattaacg acattgaggt
    22081 aaattaatga tgaaagtaat tttttttggg ttagggtcaa ttggaaagag acatctaaaa
    22141 aatctaataa gctatggaaa aaagaattct attaattttg atataacagc ttatagtagc
    22201 agtggaaaaa aagagtttga agaaataacg tatattcaaa atagagacga tttggataca
    22261 cattatgata tagcttttat tacaaatccg acttttaagc atctggaaac actaaatgta
    22321 attgttgaaa aagttgatta catattttta gaaaaacctg ctttttctga gagtattgat
    22381 cttactcaat ataattatga ttacaaaaat atttatgttg ctgctccact gaggtataaa
    22441 aatatcatgg aagttgttcg taatagtatt caaagtaaaa aagtatattc tgtaagagct
    22501 atttgttcta cttatcttcc tgattggaga aaaggtactg attatagaaa taattattct
    22561 gcctttaaat ctatgggggg aggagtagaa ttagactgta tacatgaatt ggattatatt
    22621 ataaacctat ttggtttccc taaatcagta aaaaaacagt ttggtaaata ttcgaatctt
    22681 gaaattaaca gtaatgattt agcaacatat atattgagat acgatgataa aattatagaa
    22741 attcatttag attattttgg aagagttcct acaagaaaat ttcaattgtt tactttagat
    22801 gaatgtatca atgttgactt attaaataat aaaataagtt ttgaagaaaa cattgttaaa
    22861 gaaatgcctg aatctgctaa tgatatgtat gagaaggagt tgaaatattt ctttgaaaac
    22921 gtagtaacag gcaaagaaaa ctggaatgat ttatatcatg caaacgaagt attgaaaata
    22981 gctgaggaga aataaatgga aattttattt actatttgtg gtagagctgg gtctaagggg
    23041 tttaaaaata aaaatttgaa atatttggca ggaaagcccc tagtccattt cgctttagca
    23101 atgatagata tctatcaaca aaaacatcct gaacataatt gcacgacttg tttgaatacg
    23161 gacagtaatg agttagtaga attgacgact aagttaaatc cgtctgtgaa aattgtagaa
    23221 cgtaaacctg aattagctac agatactgta gggaaaattg aagtgatacg tgattcattc
    23281 ttacaactag aaagagaaga taatatattt gatttaatta tagatttaga tttgacttca
    23341 cctttacgtg aagtttctaa tcttgaagaa ttaatagatg aacatctaaa aaatttagat
    23401 aaagacgtct acttttcagt tgtttctgca agacgtaatc cctattttaa tatggtaaaa
    23461 agaattgaaa atgaagttac tatagttaat aaatcaagat acacatctag gcaacagaca
    23521 cctgaagttt ttgaaatgaa tgcctcaatg tattctttta aacctgaatt tctaaaaaaa
    23581 agtaattata tttttgatgg gcaatgtggg ataataaaaa tgagagatta tctaatttta
    23641 gatattgata gtgaagaaga ttttaaatgg ttagaatttt tgtttcctaa atttttagaa
    23701 gattcttcgg agcttcaaga tatctataat tatttatatc ggaggtaaaa ggatgagctg
    23761 ttatcttatc accggtgggg ctggcttcat tggttctacc ttagccaatc atttaggaga
    23821 agaacatgtg gtaatcgtcg tcgatgactt atcaatggga aaagtagaaa atcttgatat
    23881 gacgaaaaat atcactttta ttgagggaga tgtcgctgag aaatccttga tggaagagat
    23941 catgaaagct aataaatttg attatatctt tcatttagca gcagttgcta gtgtggcaga
    24001 ttcagttgcc cgaccagtag aaacacatcg tgtgaatttt gaaagtgtat taatgatttt
    24061 agaattgatc cgcaagtatc aacctgattt aaaacggatc gtgtttagtt cttcagcggc
    24121 tgtttatggg gatgaaccga ctttaccaaa aaaagaagag tccgtgattc gcccattgac
    24181 gccttatgcg gttgataaat tcgctgcaga acaatatgtg ctagattatt gtcatttata
    24241 tgatgtaccc ggtagcgcag ttcgtttttt caatgtctat ggtccaaatc aaaatccgaa
    24301 ttctccatac agtggtgtga tttctattct cgtagatcgc tataagaaac aaatcgtagg
    24361 agaagcaact tcatttacat tatttggtga tggaagccag tctagagact ttgtttatat
    24421 agatgatgta atccaagcat tacttttagt tgcgaatgag gaagctgcac tggggaaaca
    24481 attcaatgtt ggaacgggta aagcaaccac acttttggaa ttgattcatg caatcaatga
    24541 aattctcggt gtagaattga cacttgaata caaagaagag cgttcgggtg atatccatga
    24601 ctctctagca gatattacta agatccagtc aattggctat caaccgaaat atggtatttt
    24661 aagtggaatg actaattatt tgaaaactga aatcaattaa aacatactaa gataagatta
    24721 gagggtaaat tcaggctctt tgtcaataag gactgatgag ttttgtaaaa tcaaatctgg
    24781 gatagaaggg ctctttgtca aatgatgttg gtaaagagaa atcttagaat aatttggaca
    24841 gaacagaaag aagaaaacct ctttctgttc tgtttatttg gttaaaaatg ttttgccatg
    24901 acgaatcata attcgtagtt tgaaattgta aaagttg
//
LOCUS       DAFENC010000037        24497 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.037, whole genome shotgun sequence.
ACCESSION   DAFENC010000037
VERSION     DAFENC010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24497
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.037"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(24..599)
                     /locus_tag="LP493_001971"
     CDS             complement(24..599)
                     /locus_tag="LP493_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBL2134118.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(604..1578)
                     /locus_tag="LP493_001972"
     CDS             complement(604..1578)
                     /locus_tag="LP493_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleosidase"
                     /protein_id="HBL2134119.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIASALKVNPNIGKHMERFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEEAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(1602..1646)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1861..2829
                     /locus_tag="LP493_001973"
     CDS             1861..2829
                     /locus_tag="LP493_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL2134120.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     gene            2926..3219
                     /locus_tag="LP493_001974"
     CDS             2926..3219
                     /locus_tag="LP493_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBL2134121.1"
                     /translation="MRSAAYGNQRRKNRLALFNDEQQEIGEMTWSDAGPDIMIVDHTF
                     VDPAYRGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            3337..3573
                     /gene="secG"
                     /locus_tag="LP493_001975"
     CDS             3337..3573
                     /gene="secG"
                     /locus_tag="LP493_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HBL2134122.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            3676..4431
                     /locus_tag="LP493_001976"
     CDS             3676..4431
                     /locus_tag="LP493_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBL2134123.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            4434..6791
                     /gene="rnr"
                     /locus_tag="LP493_001977"
     CDS             4434..6791
                     /gene="rnr"
                     /locus_tag="LP493_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HBL2134124.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKTRNGKSGKRE
                     GKQAGKRPERNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            6813..7277
                     /gene="smpB"
                     /locus_tag="LP493_001978"
     CDS             6813..7277
                     /gene="smpB"
                     /locus_tag="LP493_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HBL2134125.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIIRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            7579..8298
                     /gene="atpB"
                     /locus_tag="LP493_001979"
     CDS             7579..8298
                     /gene="atpB"
                     /locus_tag="LP493_001979"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HBL2134126.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            8351..8566
                     /gene="atpE"
                     /locus_tag="LP493_001980"
     CDS             8351..8566
                     /gene="atpE"
                     /locus_tag="LP493_001980"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HBL2134127.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            8657..9181
                     /gene="atpF"
                     /locus_tag="LP493_001981"
     CDS             8657..9181
                     /gene="atpF"
                     /locus_tag="LP493_001981"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HBL2134128.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            9168..9710
                     /locus_tag="LP493_001982"
     CDS             9168..9710
                     /locus_tag="LP493_001982"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HBL2134129.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHKGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9733..11289
                     /locus_tag="LP493_001983"
     CDS             9733..11289
                     /locus_tag="LP493_001983"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HBL2134130.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            11303..12205
                     /locus_tag="LP493_001984"
     CDS             11303..12205
                     /locus_tag="LP493_001984"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HBL2134131.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            12228..13634
                     /gene="atpD"
                     /locus_tag="LP493_001985"
     CDS             12228..13634
                     /gene="atpD"
                     /locus_tag="LP493_001985"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HBL2134132.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            13648..14070
                     /locus_tag="LP493_001986"
     CDS             13648..14070
                     /locus_tag="LP493_001986"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HBL2134133.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            14539..14769
                     /locus_tag="LP493_001987"
     CDS             14539..14769
                     /locus_tag="LP493_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HBL2134134.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            14866..16167
                     /gene="murA"
                     /locus_tag="LP493_001988"
     CDS             14866..16167
                     /gene="murA"
                     /locus_tag="LP493_001988"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBL2134135.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            16180..16356
                     /locus_tag="LP493_001989"
     CDS             16180..16356
                     /locus_tag="LP493_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBL2134136.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            16491..16787
                     /gene="yidD"
                     /locus_tag="LP493_001990"
     CDS             16491..16787
                     /gene="yidD"
                     /locus_tag="LP493_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HBL2134137.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            16851..17318
                     /locus_tag="LP493_001991"
     CDS             16851..17318
                     /locus_tag="LP493_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2134138.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASNQTRIIIRTGTTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            17403..18287
                     /locus_tag="LP493_001992"
     CDS             17403..18287
                     /locus_tag="LP493_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL2134139.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKTQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLD
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLIGAAANYLAVRQGEN"
     gene            18401..18637
                     /locus_tag="LP493_001993"
     CDS             18401..18637
                     /locus_tag="LP493_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HBL2134140.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            18725..18805
                     /locus_tag="LP493_001994"
     tRNA            18725..18805
                     /locus_tag="LP493_001994"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18759..18761,aa:Tyr,seq:gta)
     gene            18812..18883
                     /locus_tag="LP493_001995"
     tRNA            18812..18883
                     /locus_tag="LP493_001995"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18844..18846,aa:Gln,seq:ttg)
     gene            19009..19179
                     /locus_tag="LP493_001996"
     CDS             19009..19179
                     /locus_tag="LP493_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134141.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
     gene            19399..20106
                     /locus_tag="LP493_001997"
     CDS             19399..20106
                     /locus_tag="LP493_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2134142.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRRDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(20165..20809)
                     /locus_tag="LP493_001998"
     CDS             complement(20165..20809)
                     /locus_tag="LP493_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HBL2134143.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKNFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSANHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            20936..21223
                     /locus_tag="LP493_001999"
     CDS             20936..21223
                     /locus_tag="LP493_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134144.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            21331..21651
                     /locus_tag="LP493_002000"
     CDS             21331..21651
                     /locus_tag="LP493_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2134145.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIA
                     LIGE"
     gene            21969..23045
                     /locus_tag="LP493_002001"
     CDS             21969..23045
                     /locus_tag="LP493_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBL2134146.1"
                     /translation="MFDQPEAKPREVVFFWTGQLTEKQTEIAKRILCHSEKRHHLIWA
                     VTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNELFLRYRYVFPEEKITLLHGNTA
                     TAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYNGDAGLAHAVQTAIRSNGRFIY
                     LSATPDEKLLKEIKQTFELHKLALRFHRRLLPEPVLVFMNNWRQKCGNKKKINSLVRI
                     IQQLIKENRILLFCPSITMMHRLKITLQEAFPEYEITDVSSQDDQRAKKVQKMREAIY
                     EILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQIAGRADRKGPYTNSRVYFFYE
                     EKTSAIRKACQEIKEMNEEGKQML"
     gene            23042..23761
                     /locus_tag="LP493_002002"
     CDS             23042..23761
                     /locus_tag="LP493_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HBL2134147.1"
                     /translation="MRCSCCGKDIIQNLTFSEIIGVSKSRLPQTCSVCRAQFHLLEAK
                     GCAGCQKPIHLKYEETKKKANTSFVYCNDCQEWKKKYPAYDFQHRAFFTYDEKMQAWI
                     NRYKFMGDIRLAGTFAYKWTQIKKDYPAYIYCPIPLSEKRWLERGFNQVSEMLKAAKI
                     PFQMLLKREQHLLAQAKNTRKERLEMPQPFELAVPLSKIQHKKILIIDDVYTTGQTLF
                     HAADCLQNAQPKIIRTISLAR"
     gene            23889..24440
                     /gene="raiA"
                     /locus_tag="LP493_002003"
     CDS             23889..24440
                     /gene="raiA"
                     /locus_tag="LP493_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBL2134148.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
BASE COUNT         8120 a         4275 c         5269 g         6833 t
ORIGIN      
        1 tttgctaatc cagctctgtt tattcagcct atttttcttt ttgaatatat caagcgttgt
       61 ggcaacatag tgatgactaa tgaaacaacg acgatagaca acaaacgatc aaggtagtct
      121 gtacctgcct gtaccaagat cacacttgtt gtctgactta aacctaaccc atgtaatagc
      181 tgaacgatca tactggatcc tgaggaggtg atcccgccaa ataactgaac ggtaatgatc
      241 gaagaaacga tcgttccagg taccgacaaa atcaaagcga gtaataacag tttcaagctg
      301 tttttatctt tgccgagata tcttggcaaa atcaatccag caagcaagcc tgtgagaatt
      361 tggattggcg aataatacag agaaaaaata tctgtagtca ctccacttaa aataccgctg
      421 gacaatcctg tcagcattcc aggtacaggc ccaagcaatg caccagcaaa aatcgttccg
      481 atagaatcga gatagattgg caaacgaagc cataaagcaa tcgttcctcc aatataattg
      541 atcccaatac acaaagccat cactgtaagt acgcgagttg ccattttgtt tttattcatt
      601 ttgttagccc atctttaacc tttccaaatc tttcataatc gtttcttctt gtgcatttaa
      661 aagaacggtt aaaaactttc ggaaaaaaag acgagtatct acttttgtca taattttact
      721 gttagcaggt ttctgccaaa attcataacg atcaaccaat gtttgtccac gacttattcc
      781 ttgagtttcc acagcagtga agcttttgaa accttcacag atggcctcct cgataaaata
      841 agcaacagct aacggatcat tgatgacaca tcctaaaatt ctttcttgtt tccagtggaa
      901 gtcaaaataa aaacgagtga tcgcttttag atactctccc tcttcaggat tcatttgaca
      961 gcagtattcg aggatagtcg gtgtcaagac gatttctctt gtcacatcta acccaaccat
     1021 ttctatcgtt tgtttgagat tctcgaatac ataagaagct gcttcaggat cacaccagta
     1081 attgtattca gcaactggcg aacagttacc atggcttttg taagttccac ccatcgagac
     1141 aaaacgttcc atatgtttcc caatatttgg gttgactttc aaagcagaag cgatattggt
     1201 caaaggaccc aaagcaatga ctgatgtatt tgtcttttct ttgaaataat cagccaaaaa
     1261 atcaacggca tggagaggtt ctgcctgttt tctcaagatc atcgggaaat ttgtttcccc
     1321 taaaccatcc ataccatgag tgtcttgtgc actgatgaaa ggttgcttca aaggtttttc
     1381 cattccttga taaacaggaa tgtctaaacg atcacagcgt tccaggcatt tcagcacatt
     1441 ctgcgtacct atatctgcag ggacattccc acaaactacg gtaatagcaa ctacttcgat
     1501 atcaggggat ttgacagcta atgataaagc taaagtgtcg tcgatccctg gatcgcaatc
     1561 aataattact tttcgcatta tttccaatct cctttcttta gagatactta gttttttatt
     1621 ctgggaagtt tccgaaccag tccaagacga gcgtcttgat tataatgcac gaaattagta
     1681 tactggcttt tattgcgaat gtaaatgctc tcttacaagt aaatctattg aggagaactt
     1741 taagtaaatg atacaatgaa aaagaaatgg aatttacgtg tgccgaaaat aaagaatcct
     1801 atggatcggt acattggata atagatagat tatagtttgg cagaaagcgg cgggtgtaca
     1861 atggttattt tttatttcat tcttattctg ataattatag ggatcagtta ccattttctt
     1921 tcttattttt atgcaaagaa attagtaaga gcgggagtac agagaggata tgactggtat
     1981 gaagacactg gtcatcgttt gatggaccct gctgcagtca cgtcagtaga aaaaaaacga
     2041 caaaaattag aagaagagtg tgaaagcttt tgggagcagg gaacacccaa aacaatcaaa
     2101 agttatgacg ggttgaaact agctggtcag atgttcatcc atccaaataa gcagaataaa
     2161 tgggtcattt gcgtacatga ttaccgaagc acagggaaaa gagacatgtc tcatataggt
     2221 aaaagatatg cagagaaagg attcaacgtt cttgtacctg atttacgtgc gcacggagaa
     2281 agtgaaggag aaatcatcgg aatgggatgg ctagatcggc tagatttaat tgcctggatc
     2341 caactcatct tagatgaaca gccgaatgcg tccattattt tacacggcgg atcaatggga
     2401 gcttctacga tcatgatggc aagtggtgaa aaacttccat cagcggtcaa aggatttatt
     2461 ttagacagcg gatatgtttc tgtttatgca gaattccgat atatgttaag taaaatcact
     2521 gtctttccta aaaaaatggt catgagatat gcgaatcatt atgcccagaa atacgccggt
     2581 tactccttaa agcaagcatc agctacgaga cagcttggca gcaatcatct gcctttatta
     2641 gtcatccatg gtgaaagaga tcattttgtc cctacagaag cagcgtacac gattcaaaat
     2701 gctacggcag gggataaagc actgctgctt gttccggaag cagaacactt ggaagcatcg
     2761 atgaaagatc cgaaaaccta ttggacagtg attttttcat ttattgaaca aagaataacg
     2821 atgaattaat tttctcttct tttttgtaag taattcgagg ataaataatt gtttatagat
     2881 caggagactg ctaaaataag gtaggaataa aaaaatatca gttatttgag gagtgcggca
     2941 tatggaaatc aaagaagaaa aaatcgtctt gctttattca atgatgaaca acaagagatc
     3001 ggagaaatga catggtcaga tgcgggccca gacatcatga tcgttgacca tacatttgta
     3061 gatccagcat atcgtggtca aaagttagct gaaaagctag tgtatactgg agtagaatta
     3121 gcaagacgag acgggaaaaa gatcattcct ttatgccctt atgcaaaaaa agagtttgaa
     3181 aagaaaccag aatatcaaga cgtcttacgt cagtcataag aataacagct gaaagttttg
     3241 aactttcagc tgttattcca tttatataga gttgtcacgg acttttatct atgataaagt
     3301 taaagagacg atatcttttg ggaaggaggc tgcgatatgt ataatttaat tttgggaatc
     3361 gtgatcgttt tatcgattgt tatggtcatt gcgattatga tgcagccaag caagcaaaat
     3421 agtgcagcga gtgcatttac cggcggtgcg gatcaactat tcggcaaaca aaaagctcgc
     3481 ggctttgaag ctgtcatgca gcgatcaact gcagttatgg gagctatctg gatgatctta
     3541 ttatttgtcc tagcatattt atcttcgaag tagttgaata agcctctcgc aaaacggcgg
     3601 gcggcttttt ttattgcaaa gagaacgctt aagaagaagt tatgaaagaa actatggtaa
     3661 aatgaggcga aagaggtgag acgagtgaga caattaccaa aaccccttta tgcaaaacat
     3721 ggaaagcgag cggttttgct gcttcacgct tactcaggaa gtccaaacga tgttcgaatg
     3781 ctcgcacgat ttttggaaaa agcagattat acagtttatg cgccgctttt taaaggacac
     3841 ggaacaatgg agccatatga tatcttgcaa gaaaaagcag aaagctggtg ggcagacact
     3901 aaaaaagcca tccatttttt acagtctgag cagttttctg atattgccgt attaggatta
     3961 tcaatgggcg gcatctttgc tgtacgagca ctagaagaag aatcagtgat tggcggcggt
     4021 tttttctgtt cgcctttgtc tcctgtaaaa acaaacgtgc ctgaaaactt tgaaaaatac
     4081 gtacgtcaag tgctgaagac agcaggtaaa tcagagaaag aaatcaatga aaaagcagtt
     4141 gcttaccgct cgttagctga acaacaatta atggatatac aagatcaggc agcaatcgta
     4201 gaaagtaggt tgtcagatat ccaacagccg atatttttag ctcaagctgg gaaagatgaa
     4261 atgatcgacc ctaatggcgt atttgaaact gcacgcaagt tgagccgtca gcgagtgaca
     4321 cttcaatggt atcctgaaag tggtcatgtg attacagttg gtacagcaag acgcgaatta
     4381 gaaaaagacg tcttggaatt tttagaaaaa ttaccttgga atgaggaata aatatgacaa
     4441 aagaaacgat aaaagagaaa attctctttt tcatggaaag cagtcgcaaa cgcagttttt
     4501 ctatggaaga aatcgctgaa ggtttagggt tccaaaaaag cgatgatttt aaattactag
     4561 tacaaacgat tgctcaaatg gaaagagaac agagtatagt tttcaataaa aaaggaaaag
     4621 tgaaacttcc tttaaaacca atcctgatcg aaggaacatt tcgagcaaat gaacgaggat
     4681 ttggatttgt aacgattgat cccgaagaag atgacatcta tatcccaaaa gaagcgactg
     4741 gttttgcaat ggatggagac accgtagcaa tcgatatcat gaagcgagca aatacagata
     4801 tggatcgcgg agcagagggg aaagtagtcg agattcgaga ccgggcgact actcagttag
     4861 caggggaatt cgttgcttat tcagaagaag aaatacaaga aacagatctt tacggcgttg
     4921 ttatcccgaa agatagaaag ctcaaccaat ttaaagtata tgcagcagca gagggagttc
     4981 gtccagttga cggaagtatt gtgctgatcg aactgaccca ttaccctgaa aaagggtatg
     5041 cgactagttt agaagggata atcaagcaag tgattggtca taagaatgac cctggcatgg
     5101 atatcctctc aattgtcgtg gctaatggta tccctacgaa atttcctgat gatgtattgt
     5161 ctgaagcaga tgaagttcca gatcaaatca gcgaaaagga tataactgga cgtagagatt
     5221 taagaaatca gctcattgtt acgattgatg gagaagatgc aaaagatcta gatgatgcag
     5281 ttacggttaa aaaattagat aacggtaatt attttcttgg agtacacatt gcagatgttt
     5341 cttactatgt gacacaaggc agtcaattgg acagagaagc atatgaaaga gggacaagtg
     5401 tatatttgac tgatcgagta attccgatga tcccgcaacg tttatcgaat ggtatctgtt
     5461 cactgaatcc ccatgttcca aggctgacca tgagttgcga aatggagatt gatccaaatg
     5521 gacaagtagt ctctcatgat attttcccaa gtgtgatcca aacaacagaa cggatgacct
     5581 acacagctgt caatcaaatc ttagaagatc aagacgaaga aacgatgcaa cgctatgctc
     5641 agctcgtacc tatgttccaa gaaatgggtg aattgcaccg aatccttgaa acgatgcgaa
     5701 tcaaacgtgg cgcgatttct tttgaggatc gcgaagcgaa aatccttgtt gatgctgaag
     5761 gacacccaaa tgacatccag ctaagaagca gaggaattgg tgaacgcttg atcgaatctt
     5821 tcatgcttgc ggccaatgaa acggtagctg aacattataa taaattaaat ctgccgttta
     5881 tttaccgaat ccatgaacag ccaaaagaag aaaaaatgca gcgcttcttt gattttgctt
     5941 cagctttggg cattctggtc cgaggaacga aaggaacgat cacaccaaaa gatttacagc
     6001 atgtgatcga aggagtagaa gacaaaccag aagctgcagt tatcaatact atgttgctaa
     6061 gaagcatgca acaagcacgc tattcagaag acaattttgg gcattatggc ttagcggcag
     6121 attactacac acactttaca tctcctattc gacgctatcc cgatctaatc gtccatcgtc
     6181 tgatccgttc ttacagtgaa gataaaagtg aaagcaatca aagttcgtgg gctgcggaac
     6241 ttcctgaaat tgcagatcat agttctaaga tggaacgtcg tgcagtagaa acagaacgtg
     6301 aagtagattc catgaagaaa gcagaattca tgatggacaa agtgggagaa gaattcgatg
     6361 ggatcatcag ctctgttgtg aaattcggcc tgtttatcga actgccgaat acagtagagg
     6421 gattgatcca tatcaatgaa ttgaaacagg actacttcca ttttgttgaa aatcatttag
     6481 ctcttgtagg tgaaagaact ggtctgactt ttaaaatcgg acagaaagtg cgagtaaaag
     6541 tagtcaaagc tgatccagat gaacgagcag tagattttga acttgtttcc gcagaagagg
     6601 ttacagcgtt ggaacggcca aaaacacgaa atggaaaatc aggaaaacgc gaaggaaaac
     6661 aagcaggaaa acgcccagaa agaaatggca agaagaacaa acgatatagc gatagtaagc
     6721 aaacgttcgg taagaaaaaa gggaagaagc cattttacaa aggtgttaaa aagaagaaaa
     6781 agaaaaaata aaatgagttg gaggaaacag ctatgccaaa aggcgaggga aaattaattg
     6841 cacaaaacaa gaaagctcgc catgattatt cgatcatcga cacgatggaa gcagggatgg
     6901 tcttgcaagg aaccgagatc aagtcgatac gaaacagccg gatcaatcta aaagatggat
     6961 ttattcgcgt ccgcaacgga gaagctttct tgcataatgt tcatatcagt ccttatgaac
     7021 aaggaaatat ttttaatcat gatccgttgc gcacgagaaa gttattatta cacaaaaaac
     7081 aaatcatccg gcttgaaaat gaattgaaaa atactggaat cactgttgtt cctttaaaag
     7141 tctatattcg taacggctat gccaaggtat tgattggtct ggcgaaaggg aaaaaatctt
     7201 atgataaacg ggaagatttg aaacgaaaag atatcgatcg acaaattgat cgaacattaa
     7261 aaaatttctc tagataattt cattatcctt tttcgcatat tcggtgcttt tgcttttact
     7321 taatgataaa atttgttagc atttaatctg ataaaacatg attatcatag gttttttctt
     7381 agatcaggag caccgtgtat aaagaaaaat tcgcttcgtt tttgactgaa ataaaaaagt
     7441 gtctaatttt catgaaaatg ttttgaattt tctgtttcat ggtggtatga taccgtgtgg
     7501 ttagaaaccg attggaaaaa accagatacg cacatgaatt gattttatgt gaatttcggg
     7561 gaaaagaggt gaaatggatt ggatgaacgc tcgctaacgt tccacattgg accaatttgg
     7621 tttgatggta cagtttgtat aatggtgtta ctgacctgtt tgattgtttt cttcttagct
     7681 tactttttta caagaaatct taagttgaaa ccaacaggca aacaaaatgc gatagaatgg
     7741 gtcattgatt ttagtcgagg aatcgtaaca gataatctgc ctagaaaaga attgagcaat
     7801 ttccatttgt tggcatttac attgttttta tttgtttttg ttgcaaacaa catcggttta
     7861 gtaacaaaaa tcgttttacc taacgaaaca acactttgga aaagcccgac agcagacccg
     7921 tttgttactt taactttggc atttataatg atcttactta ctcacttatt cggggtgaaa
     7981 aagttaggct tcaaaggata tttcgtaaat tcgttcttga aaccctatag ttttatgttt
     8041 ccgatgaaac tgattgaaga atttacaaac ttattaacac ttgctttacg tctttatggg
     8101 aatatttatg cgggggaagt tttgctaacc ttgattgcaa aaatgatgac aagcttaggc
     8161 tggttctcat taccattagc aattccatta gagatggtct ggatcgcgtt ctccttgttt
     8221 attgggagca tccaagcatt tgtctttgtc actttgtcaa tggtttatat gagccataag
     8281 attgaagtag aagaataata ctcggttaaa aaacaaacta ctatttatct attttaggag
     8341 gaaaacaatt atgaattata tcgcagcagc aatcgcaatc atgggagcag caatcggagc
     8401 cggttatggt aacggtcaag ttatctctaa aacaatcgaa tcaatggctc gccaacctga
     8461 aatgtctggt caattccgta caacaatgtt tatcggggta gctctagttg aagctgttcc
     8521 tatcttaggg gtagttatcg ccttgattct agtttttgcc gtttaattga atcagtatta
     8581 aggcagaaac aacatcgttt gttactgctt ttttacatgg aaactagaaa tactccaaag
     8641 aaaggaaggc tcgcctatgc tgaatcaatt ggcaattgca gaagttggca atgcgatgtt
     8701 aggtaatatc atcgttgtca gcggctcatt tttgatacta ctggctctct tgaagcactt
     8761 tgcttgggga ccaatcagcg atattttgaa aaaacgtgaa gacaagatcg ccaatgattt
     8821 agattctgca gaacaatctc gcatcaactc agcgaaaatg gaacaagaac gcgaacaaca
     8881 attgttagcc tctcgttctg atgcagctga tatcatcaaa aatgcgaaag aaagtggaga
     8941 attaagccgc caaaatattt tgaaggatgc tcaagaagaa gcagctcgtc taaaaagcaa
     9001 agcccaagct gatatcactg tagaacgtga ttcagcgctg aactctgtaa aagacgacgt
     9061 tgcagaactc tctcttcaaa tcgcggaaaa aatcttgaac aaagaattat ctccagaaat
     9121 gcatgaatca ttaatcaatc aatacattga aggtctaggt tcttcaaatg aaactagata
     9181 aatatacagt aggaagacgt tacgggaaag ctttatttga actggcgatc gattcaaatc
     9241 aagcagaaga aatctatcaa gatctcgtaa gtttacgtca aatctatgaa caagtacctg
     9301 gattagggaa tatgttaagt gatgttcgtc tagaacctca tgaaaaacga gaaatcatgg
     9361 acaagcttgt cagcggttat gatgggatcg ttaaaaactt tttagaagtt gtttatgagt
     9421 ataaccgaat ggatgacctt ttgttcatga tcgaagaata tgaacgtcga tatgatgaac
     9481 ataaagggtt actattggga agtgtcacaa cagcagtccc actttcagac gaacaacgaa
     9541 tacaattaga aaagaatgtt gcaaaaacaa tggactatca atcagttgaa ttaaaacaaa
     9601 tcgttgattc ttctattatt ggtggcgcga ttgttgaagc caaccatcga gtaatcgacg
     9661 gaagcattcg cacgcaatta gaaaaaatgc gtaatcaatt aaacagatag tacaaagagg
     9721 taggtgaatc gaatggccat caaagcagaa gaaattagtg ccttgattaa agaacaaatt
     9781 gaaaattatc aaaacgtgct ttcagtcgaa gaaatcggta ccgtaactta tgtaggtgac
     9841 gggatcgctc gtgcacatgg tttagaaaac gcgatgagtg gtgagttgct tgaattttca
     9901 aacggctcat acggaatggc gcaaaactta gagtcaaatg atgtaggtat cattatcctt
     9961 ggcgatttcg agtccattcg tgaaggagat aaagtaaaac gaacaggtaa gatcatggaa
    10021 gttccagttg gagaggcctt gatcggtcgg gtagtcaatc cgctaggtca accaatcgac
    10081 ggactaggtg aaatcgttac tgacaaagct cgtccagtag aagcgatggc accaggtgtt
    10141 atgcaacgta aatctgttaa cgaaccaatg caaacagggc taaaagcgat cgacgccctt
    10201 gtgccaatcg gacgcggaca acgtgaatta gtcatcggtg accgtaaaac agggaaaact
    10261 tctattgcga tcgatacgat catcaaccaa aaaggtcaag atatgatctg tatctatgta
    10321 gcaatcggac aaaaagattc tacagttcgt acacaagttg aaacattgaa aaaatatggc
    10381 gcaatggatt acacaatcgt tgtgaatgcc ggtgcgtctc aaccagcacc attgctttat
    10441 atcgcaccat atgctggtac tgcaatgggt gaagaattca tgtacaacgg taaacatgta
    10501 ttgatcattt ttgatgatct ttcaaaacaa gctgttgctt atcgtgaact ttccttgcta
    10561 cttcgccgtc caccaggtcg tgaagcttat cctggggatg ttttctactt gcactcacgt
    10621 ttattagaac gtgcagcaaa attaagtgat gatttaggtg gcggttcaat gactgcctta
    10681 ccatttgttg aaacacaagc tggagatatc tctgcttata tcccaacaaa cgttatttcg
    10741 atcactgatg gacaaatctt cttagaaagc gacttgttct acgcaggtac tcgtccagcg
    10801 gttgatgccg gactatctgt atctcgtgta ggaggttctg cgcaaatcaa agcaatgaaa
    10861 aaagttgctg ggactttacg cctagactta gcaagttacc gtgaattaga agcatttaca
    10921 caattcggtt ctgacttgga tgcagcaaca caagcaaaac taaatcgtgg acgccgtaca
    10981 gtagaaatct tgaaacaaaa attgcatgca ccgctagctg ttgaaaaaca agtagtgatt
    11041 ttgtatgctt tgacacatgg attcttagat agtatccctg tagacagtat tttagacttc
    11101 gaacatgaat tattcgaata tctggatacc aatcattcag atatctttga aacaatccgt
    11161 acaacaaaag atcttccaga agaagaagcg ttgaacagtg cgattcagga atataaagac
    11221 atgttcttag ctacaaaagg aagtaattcc tctacagaag ataaattgaa atccattcaa
    11281 aatgcatagt gaggtgagat gaatgggtgc ttcattaaat gaaatcaaga cacgtatcgc
    11341 ttcaacgaaa aaaacgagcc aaatcacgcg ggcaatgcag atggtgtctg cttctaagtt
    11401 gacaaaatct gaagcttctt cacagaagtt tcaggtttat gcaacaaaag taagagaaat
    11461 cgttacgcat ttgactgcta ctcagttaaa tgatattgcc tcagaaaatc ctagagggga
    11521 tatcaattac aacagcatgc tgctcagccg tcctgtgaag aaaactggtt atatcgtcat
    11581 cactgcagat ggcggtttag tcggtggata taacagctcg atattgaaac aaacgatgtc
    11641 tattttagaa gaagaccacc aatcacccga tgattacgtg atgatcgcaa ttggcggaac
    11701 tggtgcagac ttctttaaag cacgcggtat caatctagca tatgagctgc gcaatctatc
    11761 tgatcagcca agctttgatg aagtccgcaa aattgtaaat atggcaacaa ctatgttcca
    11821 aaacgaagta ttcgatgaat tatacgtatg ttataaccat catatcaatt cgctaactag
    11881 tcagtttcgt gtagaaaaaa tgctgccaat ctcagactta gatccagaag aagcaacgac
    11941 tttcgaacaa gaatatattt ttgaaccttc aaaagaagaa atcttgtctc agttattgcc
    12001 tcagtatgct gaaagtttga tctacggtgc gatcgttgac gccaaaacag cagaacatgc
    12061 tgctggtatg acagcaatga aaacagcaac tgataatgct gctaatatca ttgatgagct
    12121 gacggtttct tataaccgtg caagacaagg ggctattacc caagaaatta ccgaaattgt
    12181 tgccggagct tcggcactag aatagtattg agattggagg aaaaaagatg agttcaggca
    12241 agattgttca agtaatcggt cccgttgtcg acgtggaatt ttctttagac caatccttac
    12301 cagatatcaa caacgcatta gttgtttata aaaatgacga aaataaatca aaagttgttc
    12361 ttgaagcagc gttagaatta ggggacggag tgatccggac cattgcgatg gaatcaacag
    12421 atggtttaca aagaggaatg gaagtcattg atacaggcaa agcaatctct gttcctgtag
    12481 gtaaagaaac attaggtcgc gtattcaacg tactaggaga tacgatcgat ttagaaacac
    12541 ctttcccaga agatgcggaa agaagcgaaa ttcataaaaa agcaccagcc tttgacgaat
    12601 taagtacaag tacagaaatt ttggaaacag ggatcaaagt tatcgatttg cttgccccat
    12661 atttaaaagg tgggaaagtc ggactattcg gtggtgccgg tgttggtaaa accgtactga
    12721 tccaagaact gatccataat atcgcccaag aacatggtgg tatttctgta tttaccggtg
    12781 taggtgaacg tactcgtgaa ggtaatgact tgtattatga aatgaaagat tcaggagtta
    12841 tcgaaaaaac agccatggtg ttcggacaaa tgaacgaacc accaggtgca cgtatgcgtg
    12901 ttgctttgac tggtttgacg attgcggaat atttccgtga tgtagaaggt caagatgtac
    12961 tgttgtttat cgacaacatt ttccgtttca ctcaagctgg atctgaagta tcagccttgt
    13021 taggacggat gccttctgcg gttggttatc aaccaacatt ggcaacagaa atgggtcaat
    13081 tgcaagaacg tatcacatct acgaaaaaag gttcgatcac atcgatccaa gcaatctatg
    13141 tgccagccga tgactacact gacccggcgc cggcaacagc attcgcccat ttggatgcga
    13201 caaccaactt ggaacgtaaa ttaacagaac aagggattta tccagcggta gatccattgg
    13261 cttcttcttc aagtgcttta gcacctgaaa tcgtgggaga agaacattat aaagtagcaa
    13321 cagaagtcca acacgtattg caacgatatc gtgaattaca agatatcatt gctatcttag
    13381 gtatggatga attatccgat caagaaaaag tgttagtttc tcgtgcccgc agagtccaat
    13441 tcttcttgtc acaaaacttt aacgtggctg aacaatttac tggtcttcca ggttcatatg
    13501 tccctgtaga agaaacagtg aaaggattcc gcgaaatctt ggaaggcaaa tacgatgatc
    13561 ttcctgaaga agctttccga agtgttggcc gaatcgaaga cgtcgtagaa aaagcgaaaa
    13621 cactaggcta ctagaaaggg gtgccccatg gatcaatatt taacagtaaa tgtggtaact
    13681 cctgccggtt tggtctatga tcaccatgca gctatcgtcg ttgcacgtac gacagctggt
    13741 gagcttggga ttttgcctaa acatgcacca atcatcgttc cattgacgat tgatgaagtt
    13801 cgtgtaaaac gaacagattc agatacccac gtcgattgga tcgctgttaa tggcggaatc
    13861 atggaagttc gtgataatgt tgtttcaatc gttgctgata gtgcggaacg tgaacgtgat
    13921 atcgatgtat ctcgtgcgga acgtgcaaaa caacgcgcag aacgccaaat cgaagaagca
    13981 aaagcaaaac aagatacgaa cgaattgaaa cgggcaactg ttgcgttgca ccgagcaatc
    14041 aatcgtatca aagtatctaa gcactcataa aatgagatgc ggatgtttat ccgtgtttaa
    14101 gaacagtaaa aagaggttat gacagaagtg gtcagcttca agacataaga aggaatttac
    14161 gaaaattgct tctcaaattt ttgtgaaatc tcagcttatt tttcgaagaa gctacttctg
    14221 gaacaccgta tatcagaggt tgtgaaatca gcgttttgtc ctgagtatta gagaaacaaa
    14281 tggaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt cagatgattg
    14341 aacaccgttt atttggaata agggactgcg acaagacttt tgtctcagtc cctttttttg
    14401 catattttta gcatttattt cctaaaaaat gtaaggggat tcctatattt ttaagtatac
    14461 ttgtttttcc ttttatacat tttatggtat tatcatttta ttagttatta taaaacaatc
    14521 gttagaaagg acgtcattat gcaagtatac ggaattgatg cggtgcttcg aatcgtgagt
    14581 catttggcgt ttatctactt agccttctgg tctttacgtt cgttacgcat tgaaactttt
    14641 ttcagaccaa tgcataatac gcaaattaga atggcaatcg tacttttttc aattttttta
    14701 gggtacactg caagtaattt tttcttagag gttatcgctt tatgccgaaa tcttttcgtt
    14761 agcctgtaaa ttttaaaaaa aggtactatt ttaaaagcaa ggatgttata atagaaaaga
    14821 ttttgagtaa gtgtatgctc attggaattt tttggaggga acaacatgga agagatcatc
    14881 gtaagaggtg gcaatcaatt aaatggaaca gtaagaattg aaggagctaa aaatgctgtt
    14941 ttgcctattt tagctgctag tttgttagca gaagaaggta ttacgacatt agacaacgtt
    15001 ccgattcttt ctgatgtctt cactatgaat caagtgattc gtcacttaaa cgtagatgta
    15061 gattttgatg aacaaaagaa tcaagtaaca atcgacgctt caagacaatt agaaatcgaa
    15121 gcgccttatg agtatgttag tcaaatgcgt gcttcaatcg ttgtgatggg tccgctactt
    15181 gccagaaatg gacatgcaaa agtagctatg cctggtggat gtgcgattgg taaacgacca
    15241 atcgatttgc atttaaaagg atttcaagct ttaggagcaa aaattattca aaaaaacggc
    15301 tatatcgaag caattgcgga tgaattgatc ggtaacacga tttatttaga tttccctagt
    15361 gtaggtgcta ctcaaaatat catgatggct gccgtaaaag caaaaggaac aaccatcatt
    15421 gaaaacgtag ctcgcgaacc agaaatcgtt gatttagcaa acattttgaa taaaatgggc
    15481 gctcaagtct atggagctgg tactgaaaca atgcgtattg aaggcgtgga tcatttacat
    15541 gcagtcaacc actcaatcgt acaagatcgt atcgaagcag gtacctttat ggttgctgct
    15601 gcaatgacac aaggcaatgt gctgattgca gatgctatct ctgaacataa ccgcccattg
    15661 atttctaaat tgatcgaaat gggtgcagaa atcattgaag aagaaggcgg agtccgtgtc
    15721 atcggaccaa aacatatctt acctacagat gtaaaaacga tgcctcatcc tggtttccct
    15781 acagatatgc aagctcaaat gacagctatc caattagttg cagaaggtac aagtgtggtg
    15841 actgaaacag tgtttgaaaa tcgtttccaa catttagaag agatgcgccg tatgaacgct
    15901 catgtcaaaa tcgacggaaa tgtagcaatc atggatggaa accatgaatt gcaaggtgca
    15961 gaagtatatg caacagactt gcgggcagca gcagcattag ttttagctgg cttgaaagca
    16021 aatggaatca cacgtgtgcg taacttgaat tatctagacc gtggatatta taatttccat
    16081 atcaaactac agcaattagg tgcagacgtc gaacgtgtag acatggatca aacttctgct
    16141 gaaaaaacag cacaaacgat tgcttaagga agtggctgaa tgagtaacca acgatatatc
    16201 ttattaactt tgataaagat tttagtggtg atcttattgc ttatccttct ttttgtggcc
    16261 ggaacgatga tcggatatgg tgtcatcggt ggcggcaatc catttaaagt attccagcca
    16321 agtttgtgga ttcatattcg agactttttt cattgataaa taagaatcac agtggttcta
    16381 gtcgatatga agtgagccat gaagcagaac atgataaaag aaaacagaag ggaacgttga
    16441 cgttagtcgc gatccctttt tttagtaaaa gaaaagaagg aatctaattg atgaagaaga
    16501 tattgattta tttagttaga ggatatcagc gctttatttc gcctgcattt ccacctagct
    16561 gccgttatta cccaacctgt tccaattata tgataaaagc aattcaaacc catggtgcgc
    16621 taaaagggac ggtaatgggg actgcacgga tcttacgctg tcatcctttt gtcaaaggcg
    16681 gtatcgatta tgtaccattg acattccgat taacgcgaaa taagaaagat aaaaaagaac
    16741 cagattataa aaaggttgtg aaaaatacgg gtagcactga gcgataaaga aaaagaggaa
    16801 atttattgtc aaagtaacaa ctccgcaact acttatatgg gggacaaaaa atgatcgaag
    16861 aactaaacaa gaaagattta ccatggtcct tgttattaga tgcagatcct gataaagaaa
    16921 aagttcaagt atatgtttcc agagggagtg gctggatatg gaaagaaaaa gaaaaaacaa
    16981 taggtgtact gatctatgtg gcaagggaaa aagaatacga aatcgtcaat gtagcagtaa
    17041 ccccaacgta tcaaggaaag gggattggcg gaaaattact tgagacagct tttcagaagc
    17101 tttcacagct agcttcaaac caaactcgga tcattatacg tactggcact actagtagcg
    17161 ctgcgttaca cctctatcaa aaaatgggct atgtggagat tggtcgagtc aaagactatt
    17221 ttatccatca ttactctgag cccatttttg aaaatggaga tcaattaagg gatcaagtga
    17281 ttttagcaat tcacttacct aaaaatagct ttaactaata aactttcaat tcgagaaaat
    17341 gctttcaaat gctaaataga tacattacaa tagctttagc aaacaaaaag gagaatattt
    17401 ttatgggaat attagttttt gattttggtg gatcggctgt caaatatggt tgttgggatg
    17461 gcaaagagat taaaggtaag ggacaatttg caacgcctga atcttgggaa gaaatgaaaa
    17521 cgcaattatt tcaagtttat aaaaaaatac tcgtttcttt tgaagtcgaa ggaattggaa
    17581 tcagctctcc tggagtagtg aataatgaga aacaggtgat tgagggaatc agtgcgattc
    17641 cttatattca tggatttaat attttccgag atttggaaac tctgtttcaa ctcccagtaa
    17701 cgattgaaaa tgacgccaac tgtgccggaa tggctgaatt ttatgaaggt gctgcccgtg
    17761 attatcaaga tgttgctttt gttgtggcag gaactgggat tggcggggcg ttgttcacga
    17821 aaggacaaat aaataaaggg gcacatcttt acggtggaga atttgggttg atgttcttag
    17881 atggcgataa gacattcagt aaacttggta cagcggtaca gatggcttgg cgttattgtg
    17941 aacgcaaagg tctcgataaa aatgcttata ccggaaaaga tgtctttgaa ttagcagaaa
    18001 ctggagatgc aatagcaaaa gaagaagttg agagttttta tacgtatctt acaaagggat
    18061 tattcagtat tcaattttcg tttgatccag aagtgatcgt attaggcggc ggggtttctg
    18121 caaaagaagg gctcattgat gagatcaaaa gccgaatgaa gaagctgaca gaacaattcg
    18181 atctgcatga tttcgaaccg cagattttat tatgtgagta cagaaacgat gctaatctta
    18241 taggtgcagc agcaaactat ctcgctgtac gtcaaggaga gaattaagag ctttagagaa
    18301 ggtgcagctt gcataaaaga agagaatgaa atgaatagga gatttttacc taaggaatgt
    18361 tttatttgct gcagtatgat aaaatatctg agaggtgaaa atgatgtcaa aaaaaaataa
    18421 agatattgaa gtgcgtatag aagaagtgaa aaaagatatc aaaggtaaga attatgaagt
    18481 cactcagtta tttataggga aaaaaatgat tggtgagatc ttagcctatg ggccaaaaga
    18541 atatgaaatt ttctttggtg aagaagattt tggaaaagaa aaaagtcttg aaaatgcgat
    18601 agaaacagtg attcgacact ggaatctgca cgaataaaaa aatatcaaaa aaactttcaa
    18661 taaagggttg caaaaatctg gaaaattagg tattataact aagtcaggtt gatacaaacc
    18721 tttcggagga gtagcgaagt ggctaaacgc gacggactgt aaatccgttc cttagggttc
    18781 agtggttcga atccactctc ctccatttca ttggggtata gccaagcggt aaggcaaggg
    18841 actttgactc cctcatgcgt tggttcgaat ccagctaccc cagtatacca caatcgtaag
    18901 ctctcgttag ttcgagagct cttttttttt gctttgctac cttgttcctt gaagattctg
    18961 ctgaattaag atagagttaa gttaactaca agaattggag ggatccacat gaaatggaaa
    19021 gaaaaagtag acgaagcagc tgaaaagtta tatgatttgg tcaaatcaga aaaatacaat
    19081 attgaagtga atattccgaa aaaaggcgga aaagcggtcc aggtaaaatc aaaacgccca
    19141 acgaatcata caaaaaaatg gatggctaaa aaccgctaat aataacaaaa gatccataag
    19201 tcggcatttt catcgatttt agggtctttt gttattttct aggttgaaca tatctaaaaa
    19261 attgtttctg acaataggag tagggagaac gatgtgtgtc taaatcctct gttgatggat
    19321 agaaaccttt atctttttca gttgtgaatc aggtatatac cagttataat agaagaaacg
    19381 aaaggacggg tgtacgttat gtcgaatcaa ttacctgtat atatacagat tcatgaccaa
    19441 ttaaaaaatg aaatcgaaca aggtatatgg aaagtcggag accgtcttcc ttcagaaaga
    19501 gaattagcag tgaaattcaa tgtcagccgt atgacgttga gacaagcaat tcaaaacttg
    19561 gcagatgaag gaatcttaga aagaaagatc ggttcgggta cgtatgttgc gcgagaaaaa
    19621 gtacaagaaa aaatgtctgg tgcaacaagt tttacagaaa ttatggaatc acaaaatcga
    19681 gtaccgtcta gtcggacaat ctcttatttc ttgacttcgc caagctcaag tgaaatggaa
    19741 aaactaaact tgagtaaaga tgacacgatc ttgcgaatgg aacgtattcg tttcgcagat
    19801 gatgtcccta tttgttttga agttgccagt gttccacaaa agctgatcga tggctacagc
    19861 aaagcagaga ttactgaatc gttgtatcgc acgctagaag aaaaaggcgg gaaaaagatc
    19921 ggtccagcga atcaaacgat tactgctgtg ttggcttctg agaaaattgc tgactattta
    19981 gaggtaaaac gaagagatgc agttcttcgt ttgcgccaga tttcttattt tgaagacggt
    20041 acgccgtttg agtatgtgcg tacgcaatac gtaggaaatc gttttgagtt ttatttggaa
    20101 aaataaaaaa caggtgatcc ctgattcctt attagaaata aaagagaatc agaatcacct
    20161 gtttttatat atgatcagtt atcagttgct cgtgataaga aacagaaccc tcttcaaatt
    20221 ggacttgtcc gttcagcagc tcaatgatgg attctttaaa gtggttagca cttttttcat
    20281 ctacagcaca gatgacgcta acttgatcag tatattggat ttcttttata aaaaaatgtt
    20341 ggagttcaag ataattctgt aattttccta gttgcggata cgtgatcatc acagagatct
    20401 cctgttgcaa ggtaccttct acgattccaa tgtcagacaa tgcttgagag accgcatgag
    20461 tgtatgctcg tattaatccg cctgtgccga gtttcgttcc tccaaaatat cgagtgacta
    20521 ctgcagctac attgatcagt tgattttttt tgaggacttc caacatcggt acgcccgccg
    20581 ttccacttgg ttctccatca tcgctgcttc gctggatttc atttttttct ccaatgatga
    20641 aggcgctgca gttatggttc gctttccaat gttctttttt tatttcttga atgaaatttt
    20701 ttgcttggtc ctctgattct attcgtctaa gagaacagat aaagcgtgat tttttgatct
    20761 caatctcact ttgtccattt tcttttattg tacgatagcg ctcgatcatc ttgtcacctc
    20821 tttttttcat tttctttatt cagtataaat aaagttctag gttgtttcaa cactgtaacg
    20881 gttgcgcaat tgctgtagta tgcgataata aagacaaagg caggtggatc tggggatgca
    20941 ggaacgaatg aaaaagtacg atgcaattac gcattatttg aagaacaatg gcggctctca
    21001 agtaacgttg acctttaccc aatttgacga actgctgttt cccagtaacg gacttcccaa
    21061 aacagcaagg gaaagtacag attggtgggc aaatgattat aaacaccctg aaaaaggtgc
    21121 ctatggctgg ataaatgcag gctatgaagt agttgtcatc aatttggaca aagaatatgt
    21181 cgtgttcaat aaattagtga aatctagttg gctatttgat taaataaacc gcgtttagaa
    21241 aacgttgaca aatttctttc tttttatata ataaagtaac agacgcgaag aaaacgtttg
    21301 cgtagtttgt tttaaaaagg agagaaaaat atggctaaaa aaacaatcat gcttgtatgt
    21361 tcggctggta tgagcacaag tttactagta acaaaaatgc aaaaagctgc tgaagcaaaa
    21421 ggaatcgact ctgatatttt cgctgtgtcc gcttctgacg cagataacaa tcttgcaaat
    21481 aaagacgtgg atgtgttgtt attaggccca caagttcgct ttatgaaagc tgattttgag
    21541 aaacgtctgg aaccaaaagg cattccttta gatgtcatca atatggctga ttatggtatg
    21601 atgaatggcg aaaaagtgtt agatcaagca atcgcgctca taggtgaata aatagaacag
    21661 tataactatc gaacaagcga tccaaaaaat agatcgcttg ttttttcgta tattttttta
    21721 gggcgaataa tatgaatcat ttttggggta gaaggcttct gacgagagat attaaagcaa
    21781 tagactgtga ggaggtaaat ttaccaaatt atgagaagat cgcagcagtg gaacgtttgg
    21841 gcaactggat tctttgtcat cgctgtggaa tgaggacgtc cgtcattgtt ggacagcttg
    21901 cagattacgg ttatttttgt acacattgtc tatatttagg gtgatgcgac actcaacaag
    21961 atttatattt gtttgatcag cctgaagcaa aacctcgaga agtcgtcttt ttttggacag
    22021 gacagcttac tgaaaaacaa acggaaatcg caaagagaat actttgccat tcagaaaaaa
    22081 gacatcatct tatttgggct gtaacaggtg cagggaaaac agagatgctt tatcctattt
    22141 tagtggaaac tttaaaagct ggaggaagag tagcgatttg tacaccgcga gtcgatgttt
    22201 gtaatgaatt gtttttacgc tatcgttatg tttttccaga agaaaaaatc acgttgctcc
    22261 atgggaatac agcaacggct tataccttta cttcttttgt tatctgtacg attcatcagc
    22321 tataccgttt ttatcggtcc tttgatttaa tagtgatcga tgagatcgat gcgtttcctt
    22381 ataacgggga tgctgggcta gctcacgctg tgcaaacagc aatcagatca aacggccgat
    22441 tcatctactt aagtgccacg cctgatgaga agttactaaa ggaaatcaag cagacatttg
    22501 agctccacaa acttgccttg cgctttcatc ggcgcttgct tcctgaaccc gtgcttgttt
    22561 tcatgaataa ttggcgacaa aaatgtggaa acaaaaagaa aatcaactct ttggtgcgga
    22621 tcattcagca actaatcaaa gaaaaccgta tccttttatt ttgtccaagt attacgatga
    22681 tgcatcgttt aaaaatcaca ctgcaagaag cttttccaga atatgagata acagatgttt
    22741 cttcacaaga cgatcaacgg gcaaagaaag ttcagaaaat gcgagaagca atatacgaga
    22801 tactgttaac cacaatgatc ctagaaagag gagtcacatt tgaaagaatc tctgtcatcg
    22861 ttttaggagc agatcatcca gtttttacta aatcctcttt ggtgcaaatc gcaggaagag
    22921 ctgatcgtaa aggtccttat acgaacagtc gagtctattt tttctatgaa gaaaaaactt
    22981 cagctattcg aaaagcctgt caggaaatca aagaaatgaa cgaagaaggg aagcagatgc
    23041 tgtgagatgt agttgctgcg gtaaagacat cattcaaaat ttaacattca gcgagatcat
    23101 cggagtgtcg aaatctagac ttcctcagac atgttcagtt tgccgcgcac aattccattt
    23161 attagaagca aaaggttgtg caggttgtca aaaaccaatc catttgaaat acgaggagac
    23221 gaaaaagaaa gcaaatacta gtttcgttta ctgcaacgac tgtcaagaat ggaagaagaa
    23281 atatcctgca tatgattttc aacaccgcgc cttttttacg tacgatgaaa agatgcaggc
    23341 ttggatcaat cggtacaagt ttatgggaga tatccgatta gcagggactt ttgcatataa
    23401 atggactcag ataaaaaaag attacccggc atatatttat tgtccaatac ctttatctga
    23461 aaaaaggtgg ctagaaagag gattcaatca agtaagcgag atgttgaaag cagcaaaaat
    23521 tccttttcag atgctgctca aaagagagca acatctgctt gctcaagcaa aaaacacgcg
    23581 aaaggaaaga ttggagatgc ctcagccttt tgagcttgcc gtacctcttt ctaagataca
    23641 acataaaaaa atattgatta ttgacgatgt ctatacaaca ggacagacgc tttttcatgc
    23701 agcagattgc ttgcagaacg cacagccgaa aatcatccga accatttctt tggcaagatg
    23761 aatcagatgt ggaaatttga tagcgattta atttgcaaat aacctagagt tcgatataat
    23821 agaattaaga agagggaaag agtggtcctt ctccttcttg attgtggtag acgaaagggg
    23881 taatttttat gtttagatat aatgtacgcg gcgaaaatat cgaagtaact gaagcgattc
    23941 gcgactacgt tgagaaaaaa gtaggcaaac tagaacgcta tttcagtgac gcacccgatg
    24001 caacggcgca tgtgaactta aaagtttata cagaaaaaac agcaaaagtg gaagtaacga
    24061 tcccattacc ttatcttgta ttacgtgccg aagaaacttc tccagattta tacgcaagta
    24121 tcgatttggt tgttgacaaa ttggaacgcc aaatccgcaa attcaaaaca aaaattaatc
    24181 gtaaatcccg tgaaacgggc atgaatactg cagatgctgc tgctttattc aatgaagagg
    24241 acgaaaacga aaatgattct gaattagata tcgtacgtac gaaacgcctt tcattgaaac
    24301 caatggatag tgaagaagca gtcttacaaa tgaacatgct gggacataac ttctttattt
    24361 ttgaagatgc agaaacaaat ggtacaagta tcgtttaccg ccgtaaagat ggaaaatacg
    24421 gactgattga aacagactga tcagccttac ttaaataaca acgaaaactt gcagcagcta
    24481 ctgacagctg ccgcaag
//
LOCUS       DAFENC010000038        24000 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.040, whole genome shotgun sequence.
ACCESSION   DAFENC010000038
VERSION     DAFENC010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.040"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..181)
                     /locus_tag="LP493_002004"
     CDS             complement(<1..181)
                     /locus_tag="LP493_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBL2134149.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGS"
     gene            454..2925
                     /locus_tag="LP493_002005"
     CDS             454..2925
                     /locus_tag="LP493_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBL2134150.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(3028..4764)
                     /locus_tag="LP493_002006"
     CDS             complement(3028..4764)
                     /locus_tag="LP493_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBL2134151.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(4761..5465)
                     /locus_tag="LP493_002007"
     CDS             complement(4761..5465)
                     /locus_tag="LP493_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2134152.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            5596..6099
                     /locus_tag="LP493_002008"
     CDS             5596..6099
                     /locus_tag="LP493_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBL2134153.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            6059..6397
                     /locus_tag="LP493_002009"
     CDS             6059..6397
                     /locus_tag="LP493_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HBL2134154.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            6418..7836
                     /gene="ffh"
                     /locus_tag="LP493_002010"
     CDS             6418..7836
                     /gene="ffh"
                     /locus_tag="LP493_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HBL2134155.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            7948..8526
                     /locus_tag="LP493_002011"
     CDS             7948..8526
                     /locus_tag="LP493_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HBL2134156.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            8530..9051
                     /locus_tag="LP493_002012"
     CDS             8530..9051
                     /locus_tag="LP493_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBL2134157.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(9130..9684)
                     /locus_tag="LP493_002013"
     CDS             complement(9130..9684)
                     /locus_tag="LP493_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBL2134158.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            9937..10212
                     /gene="rpsP"
                     /locus_tag="LP493_002014"
     CDS             9937..10212
                     /gene="rpsP"
                     /locus_tag="LP493_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HBL2134159.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            10224..10475
                     /locus_tag="LP493_002015"
     CDS             10224..10475
                     /locus_tag="LP493_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HBL2134160.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            10600..11391
                     /locus_tag="LP493_002016"
     CDS             10600..11391
                     /locus_tag="LP493_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134161.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            11561..12082
                     /gene="rimM"
                     /locus_tag="LP493_002017"
     CDS             11561..12082
                     /gene="rimM"
                     /locus_tag="LP493_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HBL2134162.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            12072..12833
                     /gene="trmD"
                     /locus_tag="LP493_002018"
     CDS             12072..12833
                     /gene="trmD"
                     /locus_tag="LP493_002018"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HBL2134163.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            12969..13316
                     /gene="rplS"
                     /locus_tag="LP493_002019"
     CDS             12969..13316
                     /gene="rplS"
                     /locus_tag="LP493_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HBL2134164.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            complement(13448..14584)
                     /locus_tag="LP493_002020"
     CDS             complement(13448..14584)
                     /locus_tag="LP493_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL2134165.1"
                     /translation="MWIETKTDKNGKKVYKYNERYIDPKTRKRKKVSITYKNKSRETQ
                     KVALLELNKKIDIKLNEKTLQKPNLTFHELVEEWLVIYKRQVKESTYYPTNNILNTIK
                     KKMPETYIVSGINTVDLNNIFEDMIYKDDLSNKYVSVIKSKLNLLFSYAMKKGYVEKN
                     PINEVVIDYKRESKTIKIKDKFLEDDEYKRLVDFTTSHNKRYSLLFQWLYLTGMRPGE
                     AIALSKDDVHITNNNASVVINGTMMYRERSIADMKKSDSTKTAAGMREIDLPKKAIAI
                     YNELLELNPKGQFLFQTTKGTPFQLTAINTYLRNHKADMKIDKKLSSHIFRHTHISKL
                     AELGTPLYAIQDRVGHENSDITEKIYLHVTKGVKEKLKEDIEKL"
     gene            complement(14701..15393)
                     /locus_tag="LP493_002021"
     CDS             complement(14701..15393)
                     /locus_tag="LP493_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134166.1"
                     /translation="MKKVILGLVFGAFFLTGCSQSNVVDNTGKTNEKDSSVTLSESTT
                     QSSKNSQEVDGPLLKVGQWTKEKRDTSGKIELIGTASPQSDIPLGDIGIYISNIKLLK
                     YSNYADPSAAGYYDANNHKDSEGNFYGLQIAFKVKNNSEVDYGYNGLAHAILDNGQQI
                     DFSSDDLMHTMTTNSFFKKTESKEFYSLAYLDPSKVNDITKVTIKTGVLYNPSDYSTV
                     AESAESTFNINR"
     gene            complement(15531..16184)
                     /locus_tag="LP493_002022"
     CDS             complement(15531..16184)
                     /locus_tag="LP493_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134167.1"
                     /translation="MKKVSVMLLLSTALLLSACSNNKKAESTDATSNQETKVSKTKET
                     TETSSSTSKSTSKTDSSSTVTSSNQATAEPSPTVISSSQDTIQTAPQEETYEQMKQRT
                     LQSTPADRANWSNKEWEAFGVALYENGLTTDDAGNIISQDQKEQQAASQQNPEDQQTS
                     GQQDADTLSLTDFVNKYGMSPVAWKVQNGMSEEEALRTTQQKTSGEVQLGFSKYGIQ"
     gene            complement(16234..16662)
                     /locus_tag="LP493_002023"
     CDS             complement(16234..16662)
                     /locus_tag="LP493_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBL2134168.1"
                     /translation="MEMDTINLVEELKRKYRSANPFYICEKMGIKIQYVPFIENPKGQ
                     FQEIRGRAIIFLNDELRDSEERFYICAHELGHAIFHRGLSSYYVSTRTSRSKSESEAN
                     CFAANLIVSLYKEDNDQYPKKIDELKNLYGLPESAYRFLI"
     gene            complement(16667..17041)
                     /locus_tag="LP493_002024"
     CDS             complement(16667..17041)
                     /locus_tag="LP493_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2134169.1"
                     /translation="MNLLDRIKELAHKRGISITQLEEELNIPKNTIYQWKNRTPSTKR
                     LQLVADYFNVTTDYLLGRNQVPDWATKDEVVELDKLLDSNVNMSYGGETLTPEQVQRV
                     KDILIGTFWDIVKEDKEKGKKM"
     gene            17326..17511
                     /locus_tag="LP493_002025"
     CDS             17326..17511
                     /locus_tag="LP493_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2134170.1"
                     /translation="MSENLDLKIRAEMRKRRMTFKELAALVGISGAYLSDILNGNRDG
                     KKAQQHIETVKKILDIR"
     gene            17524..17772
                     /locus_tag="LP493_002026"
     CDS             17524..17772
                     /locus_tag="LP493_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134171.1"
                     /translation="MTKLKKQDFVKKYNYSPSTYQRRMSELKNTAIFSAAYERVTGQE
                     VWINTELYDKFLSFKSYNRLRTRKITPKEFIEKHLVDL"
     gene            17803..17982
                     /locus_tag="LP493_002027"
     CDS             17803..17982
                     /locus_tag="LP493_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134172.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(18025..18495)
                     /locus_tag="LP493_002028"
     CDS             complement(18025..18495)
                     /locus_tag="LP493_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134173.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            18582..19280
                     /locus_tag="LP493_002029"
     CDS             18582..19280
                     /locus_tag="LP493_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HBL2134174.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            19458..19799
                     /locus_tag="LP493_002030"
     CDS             19458..19799
                     /locus_tag="LP493_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134175.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            19792..20463
                     /locus_tag="LP493_002031"
     CDS             19792..20463
                     /locus_tag="LP493_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HBL2134176.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            20469..21155
                     /locus_tag="LP493_002032"
     CDS             20469..21155
                     /locus_tag="LP493_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134177.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGREISLK
                     DESNTTVSDANILANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVTNFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            21158..21385
                     /locus_tag="LP493_002033"
     CDS             21158..21385
                     /locus_tag="LP493_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134178.1"
                     /translation="MINLNAVAFEQTWRTKYKKMSPRDKLFLEIMTFAFIGTQAEQSD
                     ISVEKIKTNRLVNGITETCYQYTIIVVDEEE"
     gene            21388..22215
                     /locus_tag="LP493_002034"
     CDS             21388..22215
                     /locus_tag="LP493_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replisome organizer"
                     /protein_id="HBL2134179.1"
                     /translation="MAERRMFAKTIIDSDAFLDMPLSTQALYFHLSMRADDDGFINNP
                     KKIQRMVGCGDDDLKLLMAKRFILVFESGVIVIKHWKIHNYIRNDRYKPTLYQDEKAL
                     LADKDNKAYTFAEELSKHDEKLGIPDDNQAVYQMDTQVRLGKDRLGKDSKEIKDLTPS
                     KKSKAKPIRHKYGEYKNVLLSDEQMEKLKTEFPNDYQERIERLSEYCESSGKTYKNYL
                     ATIRSWARKEKSEPKNASSGYKRTGRREKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            22227..22496
                     /locus_tag="LP493_002035"
     CDS             22227..22496
                     /locus_tag="LP493_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134180.1"
                     /translation="MKIDYLELINEIAKYKTGEEIEILRDVYDQLEEAGIEGINNDRS
                     SWSKLRYYFALYIDTTQLRNLAYTKLLFVDCVKGLQKHLSELEQV"
     gene            22501..22665
                     /locus_tag="LP493_002036"
     CDS             22501..22665
                     /locus_tag="LP493_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134181.1"
                     /translation="MDLKTFTAQIELMHQEALRQSASYEDKWLNTFHGGRESALDQVL
                     KLLKGERRDG"
     gene            22658..22975
                     /locus_tag="LP493_002037"
     CDS             22658..22975
                     /locus_tag="LP493_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134182.1"
                     /translation="MDKKAAMKRIIELTHSESWQEDEEVVAEVQRLGKIANGRIRKKP
                     DKRKQRKRKIVVVLHEGKILMQGTASELSAETGYTRGTIRTYAWRNHTDRKGHEYKYL
                     EEE"
     gene            22975..23790
                     /locus_tag="LP493_002038"
     CDS             22975..23790
                     /locus_tag="LP493_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prohibitin family protein"
                     /protein_id="HBL2134183.1"
                     /translation="MNENKLIKLGVAGAVIVGIGVIGGFKFFEKIDNGYVGVRYSMNG
                     GIKDEALTQGVKFVGIDKVIQYPIRLQTIQSKNISVSTSDGKKTTIDIKYDYKVDSTK
                     AAKMYKEFGNITSEDIESGWLKSKLQKVAREVYAKYSLLDVLSGDSSKVEAEVLTNFA
                     KSVESKGFEVEDVTLGVPDVDKETQKSIDAIIRAGQENEKAKLDAETAKTQADSEAYK
                     KTKAAEAEAESNRKVAESVTDNLIRYEEAQARKKHGWVTVNGADTVVTDEAGK"
BASE COUNT         8011 a         4143 c         4809 g         7037 t
ORIGIN      
        1 aggaaccgtt gcggataata cgaaccgatc gacagtgttc acaataggaa gaagagtcat
       61 ccaattttcc tttaataaac tgcgcttgaa cgcctttata ttctttttca atcagccatt
      121 cttcatcaaa aaataaatgt ttatctgtta atccgagtaa ttttctagta tgattatcca
      181 ttgagagact cctttggtag gatgacgttt tggtcgacta aattttacca aaagtgagtc
      241 tctttttgag ttgaaacgaa gaaaaagtgt tagtagaaaa tcgccttcga ttttccacca
      301 acacaaaata ttatagaacc cttttttttt gctatatgac aggaatgaaa ggtgtttgca
      361 agcttaatgt gaggaacact ttccatatct gttctatact ggataggaga agtttggaaa
      421 tatccagaaa acgaaatcaa tcgaggtagc cacatgaaga ataaatggat aaatcgaagt
      481 aaaaaaaaga aagtaacaca aagatcatca gataaagtca tccgtctttt tccatcgtat
      541 aaagaaggat taacggcaga tcaagtcaag gaacgaatag aaaaaggtgc agcaaataat
      601 tcagtcgatc ccacattcaa aacaaatcag caaatcgtat tggaaaacat atttacgtat
      661 ttcaatttga tctttcttat cttagccatt ttgctttgtt tagtagaatc ctataagaac
      721 ttgacttttt taccagttat catagccaat acaggaatcg ccatttttca ggaaattcga
      781 tccaaaaaga tcttggacga actaaatgtt ttaaatacag caaaagtcaa tgtcatacga
      841 gacgggatag aacaaacaat agatatagaa gaccttgtaa tagatgacat tgttatttta
      901 gagactggat atcaaattcc agcagatgca gaggtcgtgg aagggaaact gcaagttaat
      961 gaggctttat tgacaggcga agcagatgaa ataaccaaag aaataggtga tccattaatg
     1021 tccggcagtt tcattgtttc cggaaaagct tacgcccgat tagacaaagt tggagcagat
     1081 tcgtatattt cccagctgac agtcaaagcc aagacaatgg gagaaggaga acagtcggag
     1141 atgattgctt ctcttaatca attgatcaaa tggattggga tcatcattat tcctatcggt
     1201 atcctgcttt tttctcaaag ttactttttt aatggaaaca cgatcaaaga aagtgtcgtt
     1261 gcaatggaag cagcattgat cggtatgata cctgaaggac tgtacttgct gacgacgatt
     1321 gcattagcat taagtgcgac taaactagca aagcaaagag ttcttttaca caatatgaaa
     1381 agcattgaga cattggcaag ggtaaatgtc ctttgtgtag ataaaacagg aacgatcaca
     1441 gaaaataaaa tgtctgttca aaaaatgatc gtctctaaaa aacaagaaat aatcagtcag
     1501 tcagatcaat tggaagcatg cattgctgac tatgcaaaag cgatggcagg agacaatgca
     1561 acaatggaag ctgttaaagc atattttaca aaaaccactg atcaatccta tcaccatgtt
     1621 attccttttt cttctgtcca aaaattcagc agtgtagcgt tggcagacaa ggtgtatgtt
     1681 ttaggagcgc ccgaaatggt tttgcgcgat caattgccgg aatatgcgga agagtttgtt
     1741 tctttcgctg aaaaaggcta tcgcgtgttg gtctttggtg tgtacgatgg gattcttgaa
     1801 gaaccagtat tgacagaagc agtcacacca ttaggctata ttctgattgc taatcctatc
     1861 agaaaagaag caagagccac atttgattac ttcaaaaaac agcaagtagc catcaaagtg
     1921 atttctggag ataatccgct caccgtatcc aatgtagctg tccaagcagg gatttcacat
     1981 gctgatcagt acgttgatgc atctaaatta tcagaagaag aatatgaagc agctgtcgaa
     2041 aaatatacag tttttggacg cgtcaagcca gaacaaaaga aaatcttcgt tcaattgata
     2101 aagcgtaaca atacagtagc tatgacaggt gatggcgtga atgatattct agccatgaaa
     2161 gaagcagact gcagtatagc gatggcttcc ggaaatgaag ccgccatgca ggcctcacaa
     2221 gtggtcttac ttgattctga cttttcacgc atgccagaag ttgttgcaga aggacggcgc
     2281 gttgtgaaca atattgagcg atcagccagc ttgtttttag tgaagaatat tttctccttt
     2341 ttgctctcac tgttttcagt gatctttgct ctgacctatc ctttagaacc atcacaaatc
     2401 acattgatta gtttgtttac tatcggactt ccatctttct tgcttgctct agaagaaaac
     2461 aaaaagcgaa tcagagggaa attcatcatg aatgtgatgg aaaaagctgt gccaggtgga
     2521 ctaacagata tgatcgtagt cggtgcgttg gtgatctgcg gggtgacttt gaatctaaat
     2581 aaaacagatg tttctacagc atctaccatg cttttgattg cagtagggtt cctcgttctc
     2641 tataaaatct gttcaccgct gaataaattc agaagtcaga tcattctttt ctgtgctagc
     2701 ggtaactttt tttcggtcat ctttttgcat aagctgtttt caatcaccgg tatctcagct
     2761 gtatcacttt tgctgttgag cattctattt ttctcggcag attcgatttt taggcatttg
     2821 accacattgg tagaatattt gtttgaacgt aaaaatgaaa aagagcaaaa gccgtttagt
     2881 cgcgtagcta aaaaatttct atcgatattt aaacgagaaa attgacgaaa agtatctcaa
     2941 aaaagagtaa aaaagaacaa ccactcgtgt atctttcgaa gcaggatgag tcatccaact
     3001 ttaaaacgca cgagcagttg ctctttttta cattttcgga atggtaacgg tgaaagtcga
     3061 acctgttcca agatgactgt ctacagtaat cgtaccatta aggagttgca cgtagtcttt
     3121 tacaatcgct aaccctaatc cggtcccgcc tgaatgtcgg cttcgcgcct tgtctacgcg
     3181 gtaaaaacgc tcaaagatcc gttcctgatc ctcaatgtcg atacctatac caaagtcttg
     3241 gacagaaaac gatagatcat ctgttgcctg atagcggata ataatctcgc tgtcgctttt
     3301 tgaatattgg acagcatttt caattagatt tttgataatt ggataaagga tatctgtttt
     3361 agtagtaaat ggttcgttct ttccaatcaa tcgaatcgtc aaccgtttct tttcgatgat
     3421 tggctgataa ttttgaacga tttgctggaa ataaggttct gtataaattg tctggatctc
     3481 gtaagaattc tcgccatctt ttgacagctg gatgatttcc cgaatcagtt tatctaaccg
     3541 gatcgcatct ttttgcatga tctcaagaaa agaagtcaga gtttgcgggt catcttttgc
     3601 accatccagt aaagtctcgg taaaaccaat cagtgaagtc acaggagttt ttaattcgtg
     3661 agagacgttg ccaacgaaat ccttttgtag cttttctaaa cgtcgcactt tcgttaagtc
     3721 atacgccacc cctagaatct gtccggtacc ttctgaatta gtaaagtagc gcaaactcaa
     3781 gtctaatgtc tgccgacctt ctgtaagggt gatctcctga tggatcagcg gatgctcagg
     3841 agtcacttga tgaatcagct gaatgagttt tggctcttga atgacttctg tgtaccgctg
     3901 ttcaggttga tagcttacca cgtttaaatg tagctgcatc tttggattaa gcagtagtaa
     3961 acgagaatca gcatcatcaa tcaggaatac gccaatcatc agttcgttca gtaacgtata
     4021 taattgctct tctgtggtag tacacgcccg atacatctta ctcatttgtt cgctcaacgc
     4081 attaatcgtc tgatacaatt cttcccattg atcgggtgtt tgcatgatta cttccgcctg
     4141 attaggattt tgcaccattt tttttagtac gggcagcacg gttttcaatg gctggttttt
     4201 ttgatagatc agataataga tcattcctgc aagaacaagg aagaaagaca gaaagaagaa
     4261 aaagacccaa cggcgaaaac tctcagttct cggtaaaaaa ccgcttgtcg gttctgcgat
     4321 acgtaaaatg gcttctaact ggccactttt tttgactggt aatgcgacat ataaaagatc
     4381 ctcattcaaa gtagtacttt tgcgcaaagc gctacctagg ttcccaccat tcaatacggc
     4441 tttgatttcg ggacgggagt ttcgctgttc attcaatgtt tcattgtttg tgtcaaataa
     4501 gatctttcca gtagcatcca ttaaagtaat ccgttcgttc gactgatgga cgaattcttc
     4561 caaagcagtt ttgttttgcg ctgcttggag gttttcgaca tctaattgcc ggatcagcag
     4621 ttgtgctttt tttgtcaggt agctttcttg ctgttccacg atctgctgtt gaaaataatg
     4681 ggaaatcaat tgccagccac caaaaaacaa actaactaaa agaataagaa agaagagacg
     4741 ttcataaatt tttttccatt tcatcgtttg ggttcctgaa acttatagcc aaatcctcta
     4801 atagtcacca agtactttgg gtgttttgga tctcgctcga ttttttctcg caaatgacta
     4861 acgtgtacat ctacgattcg gctttgtcct gcgaagtcaa aattccaaat gcggtctagc
     4921 aatgtgtctc ggtcgatcac acggtctttt cgtttcatga aataaacaag taattcaaat
     4981 tctttcggtg ttagttcaat cagatggtcg tctacggtca cttgataatt ggtcaaatca
     5041 gcagtgattt gtccaatcga tagatattca ggctcagctt catcttttga ttgcttacga
     5101 ggttcaattc gtctgaatat tgctttcata cgggctaata cttcgcgagg actaaatggt
     5161 ttggtcaaat agtcgtcagc acctatttct aggccaatga tccgatccac ttggtcatct
     5221 ttagccgtca gcatcaaaat cggtgtttca tttttttctt gacgcagccg ctgagtgatc
     5281 tccatgccat ccatcgttgg aagcatcaca tctaaaatga tgaaatcaaa tgattgttct
     5341 aatgctaatt ctaatccttc gcctccatct gtggcactgg ttaccttgta gccttctttt
     5401 tccaaattga acgtcaagag cgttacaata gaaggttcat catcaacaac tagtattttt
     5461 ttcattcaaa tctcctttaa ataggtttca ttctgtttat attttagcat agaatcagta
     5521 caaagggcta ttttacaaaa gaaataaatg gtataatagg aaggcacttt gctgaataga
     5581 aaggaagagc agtcaatgat tggaatcagt gcatgtttag gcggtctggc ctgtcgctat
     5641 gatggacaga aaaaagaagt accagaattg atggaactag ttgaaactgg agaagctgtc
     5701 atggtctgtc cagaagtgat cggcggatta ccaattccta gagatcccgc tgaaatcatt
     5761 ggtggaaatg gattcgatgt gtggaaagat caagcaaaag tatggacgac aagcggcgaa
     5821 gatgtaacgg aagcgtacaa aaatggcgcg atcaaagcct atcaaaaatt gcaggaaaaa
     5881 cacattgatc tagtcatcat gaaggaaaaa agcccttcat gcggaaccca ttcgatttat
     5941 gacggaagtt tttccggaat aaaaaaaaat ggtgccggag tggctactgc ttattttatt
     6001 cagcaaaaaa tgactgtgct ctctgatgaa gaatggctga aaactagagg tgagcagaat
     6061 ggaaatcgaa aagaccaatc gaatgaacgc gctctttgaa ttttattcga ccttattgac
     6121 agaaaaacaa atgaactaca tggaattata ttatgcagat gatttttcat taggtgagat
     6181 cgcggaagaa tacgaagtaa gccgacaagc agtatatgac aatatcaagc ggacaagcaa
     6241 gatcttggag gattatgaaa aaaaactcca tcttttttct aattatattg ttcgagaaca
     6301 ggtattggaa aatatgactg catatattac agataagtac ccggaagata aaaaactact
     6361 tgaatatgta cagcaaattc aagcaatcga agaataaata aaaggaatga agaaaatatg
     6421 gcatttgaaa gcttaactga acgtctccag caggcgatgg gaaaaataag aaaaaaagga
     6481 aaagtatcag aagctgacgt aaaagaaatg atgcgggaaa tccgccttgc cttactagaa
     6541 gccgatgtta acttgcaagt agtcaaagat tttactaagc gcgtacgcga acgtgcggta
     6601 ggggcagaag tgctggaaag tttatcacct gcacaacaaa tcgtaaaaat cgttgatgaa
     6661 gaattgacga tcacacttgg ttctgaaaca gcagagttaa ataaatcacc aaaaatacca
     6721 actgttatca tgatggctgg tcttcaaggg gcaggtaaaa cgacctttac tggtaaatta
     6781 gccaattatt taaagaaaaa tgaaaatgct cgtccgctcc taatcgcagg ggacgtatat
     6841 cgaccagctg cgatcgacca attgaaagta ttaggtcaac agctagacgt tcctgtattt
     6901 gatatgggaa ctgaagtcag cccggtagag atcgtccgtc aagggatgga gttagcaaaa
     6961 gaaaagaaaa acgactatgt attgatcgat acggcaggac gtctgcatat cgatgaaaca
     7021 ttgatggatg agttgaaaca aatcaaagaa ttgacgcaac caaatgagat tttgcttgtt
     7081 gtcgatgcca tgactggtca agatgccgtc aacgtagctg atagcttcaa ccagcaatta
     7141 ggtattacag gggtcgtcat cactaaactt gatggggata ctcgaggcgg ggcagcacta
     7201 tcgatccgct cagtgacagg cgcaccaatc aaattcatcg gttctggtga aaaattgact
     7261 gacttagaag tattccaccc agatcgtatg gctagccgta tccttggtat gggggatatg
     7321 ctgacattga ttgaaaaagc gcagcaagac tacgacgaga aaaaagcgga agaacttgca
     7381 cagaaaatgc gggaaaattc attcgatttc aatgacttta ttgaacagct tgatcaagtg
     7441 atgggtatgg gcccactgga agatctaatc aaaatgatcc caggaatgaa tcaagtccct
     7501 ggaatcgaaa acgtcaaggt agatccaaaa gatgttgaac gcaaaaaagc gatggtttat
     7561 tctatgacgc cagcagaaag agcaaatcct gatctgttga acccaagccg tcgtcgccga
     7621 attgctgccg gttctggaaa cagtgttgtt gaagtgaatc gaatgatcaa acaattcaag
     7681 gaatcaagaa aaatgatgca gcaaatgtcc aaaggggata tgaacatccc aggtatggac
     7741 caaatgtttg gttcaggcgt caaaggaaaa ctaggcaaaa tggcgatgaa tcgaatgatc
     7801 aagaaaaata agaagaaaaa gaaaaaacgg aaataagatg aaaaaaacag cttcggtaca
     7861 gactgaaaat gtctactgcc ggagcttttc tatcagcaat ttttattctt tactaataca
     7921 attactctaa acgaagaggt ggcacagatg agatgtccgt ggagtgaaca aacagaaagt
     7981 atgcggcaat atcatgatac tgtctggggt gttcctgaat atgatgacca aaagctgttc
     8041 cgaaaattga tgcttgatat taatcaagcc ggattgagct ggcagacgat tttaaataaa
     8101 agtgaagcat tcgatgaagc atatgatcga ttcgatatca aaaaagtcgc aaattatgga
     8161 gaaacaaaaa tcagtgaact aatggaaaac aaaggaatta ttcgtaaccg aagaaaaatc
     8221 gaagcagccg tccaaaacgc caaagcagtc ttgaaaattc aagaagaaat cggcagtttt
     8281 tcagagtatc tttggtcgtt ttctaatgga aaaatcgttg attcttctta tcattcacaa
     8341 gaagaagtcc caacaacaag tcctctttca gatgaattag caaaagatct aaagaaaaga
     8401 ggatttaaat ttatcggaag cacaacaatc tatgcttttt tagaagctgt cgggatcatc
     8461 aatgatcacc ttgacagttg tttccgcaaa gaagaggtcg tacgtatcgg cagaaagggc
     8521 gaataaagca tgcgaaaaat catattttat ggtgctataa gtttagatgg ctatttggca
     8581 acgaaaacgg atgatcttca atggcttttt gacactccaa caggtaagca aactacttat
     8641 gaagcttttt atgaaacaat cgatacgacc atcatgggca gaaaaactta tcaggaagca
     8701 aaaaaatatt tggagaccga agcaatttat ccagagaaaa agaatttcgt tttttccacc
     8761 cacgcacaat tacaattgcc agatgctgag gtcgtaaacg aagatcctgt tgcttttcta
     8821 aaaaatctac aaatgacaga aggaaaagat atctgggttg tgggtggcgg tcgattgatc
     8881 aaaccgctat tggaacatca aatgattgat gaatggtata tccagattac ccctgtatta
     8941 ttaggggacg ggattccttt attccaaaaa ggaacatatg aagcgcgttt tgaaatgcta
     9001 gacacgacac gattcggtga atttatcgaa ttgcattatg tacgaaagta gaagtaaata
     9061 aaataaaaaa ggcaactata tgcagaaatg tcctgtacat agttgccttt tttattaccg
     9121 ttatgctttt tactctgtta atttgttaga aaaatctaga tacgcatcta aaatcgtttg
     9181 gaagaaactt aatgttcctt caacgatatt accattttca tcaattagat tcgcaacgtt
     9241 tccgatatat gcttccggtt gctgcaaggt tggcacattc aaaaagacaa gtgattggcg
     9301 tagatggtgg tttgcgccaa agccgccgat cccacctggt gatgcagtaa cgactaaacc
     9361 tggtttatga tcccaaacac tgtgtccata aggtcttgag cctacatcta aagcattttt
     9421 caatactgct ggcacagaac ggttgtattc aggagtaacg aaaacgacac cgtctagtcc
     9481 cctcacttcc tcacgaaaac gagtccattc agcaggagcc tgttctggag tttcgagatc
     9541 ctcattgtaa aatggcagat catcgatttt tacaaataca ctttcgtacc cttcaggaag
     9601 caatttcgca aaagcttctg ctactttttt gttgtaagaa tcttttctta aactaccaat
     9661 aaaaaatcca attttttttg tcatacgatt tttcctcctt caaactatct ataataatct
     9721 tacaaaagat aagtaactgg agcaaataaa aacacttact gacaaaagct acatagaaga
     9781 tagattactt atttttaaca aaaaagaagt ctaaaatctt ctattttcta aaaaaaatcg
     9841 aatttaatca agctgtaaag aaaaaaagct ttacagggta aaaaaaaact gttacactac
     9901 atcttgtgaa taaaacaatg gaggtggaaa taaataatgg cagttaaaat ccgtttaaaa
     9961 cgtatgggtt ctaaaaagag tccgttttac cgtatcgtcg tagctgattc acgttctcct
    10021 cgtgatggac gtttcatcga aactgtaggt acttacaatc ctttgaaaga ccctgcagaa
    10081 gtagttttaa aagaagactt agttcttgac tggttatcaa aaggtgcaca accttctgac
    10141 actgtacgta acatcctttc aaaagaaggc gttatgcaaa aacaccacga agctaaattc
    10201 tcaaagaaat aaggtgaccg gatatgaaag atttaagcga cttagtctta acaatcgttc
    10261 gtccgctagt cacttatcct gatcaagtca agttagacgt cgtagagtcg aaagactttt
    10321 acgagtacaa tctaacagtg gctcctgaag atattggccg tatcattgga aaacaagggc
    10381 gtgttgctaa agcaatccgc acaatcgttt acggtgttcg gatcaatgca ccgaaaaaag
    10441 tgcgtttgaa tatcatcgat gataaggaaa agtaaataaa cgtgctgtac tcgaattttc
    10501 gagtgcagct tttttgtttt ttttattaat tgaagaaatg attatttggc aaaacaagca
    10561 agaaagcgta tccttatagg aggagggagt gaacagccaa tgagaaagaa aatgttattt
    10621 attccatttg ctctattgtt aagcgcttgt agttcggtta ctcaagaatc agacaataca
    10681 catctatcaa gcagtatatc tgaaactgtt accagtccag aaaaaagtag taccaaaacg
    10741 gcttccacca ctgaacaaac aatggctacc tcaaataatg agaaaaagac tgctttagac
    10801 cagttgaaag aacaacagcc aaatgttccc atgcctctag atgtaccagt ctcttcaggc
    10861 tatctcaata tcgcagcgac acatacaaag caaggttatt ctattttata ttacagaaca
    10921 gatcgtcccc tcgggttgaa tgctgacgaa ttgaatcaag aaacgcctat tgcaacctat
    10981 ctatatcaat atgggtttgc ttctagtcaa gaaacaatcc aagttttgca gccatttgag
    11041 atcgacacaa atggtcagca agtggactta ggttctcgaa tcacagggta tcagcaaggt
    11101 gcagcaggtt caagttttct tgaatggcaa gaaggaaact ggcgtattcg aatccgtggg
    11161 aataatatag aaggccaaga tcccttacta ttagctaaag aaatcgtagc ttatttggaa
    11221 gaaaacagtc taccagcacc tgaacaattt ggtaaaatta ctgttgatat gggtgatacg
    11281 acgaatcgag ccgtagaagt aagctggcaa gaaccgaaaa atgcctatac gatcactcat
    11341 caagatccta tgtctgcgtt gaagatggca gtttctatga agaggttgtg aaatcagcgc
    11401 gctgatctga gcccatcatt taactccaag tcacaggaag taatcaaaaa tagcacgccg
    11461 catttttgca taattttggc ttaatacctt aaaagaaaac tagaattgcc tcttcacaca
    11521 tgctaaaata aaacagacaa aaaagaaatg gggatataag ttgactgaat acttgaatgt
    11581 aggaaaaatc gtaaacacac aaggtatcaa aggcgaagtc cgtgttatct caacaacgga
    11641 tttcccagaa gaacgttaca aaaaaggaac ggtgctaaca ctattccaag acggaaaagc
    11701 acctgtggaa ttaacagtca aaagtcatcg caaacataaa aattttgact tattgagttt
    11761 tgaaggacat ccttctatca atgatgtgga aaaatatcgg gatggcatat taaaagtgtc
    11821 aaaagacaac tctgtagatc tagctgaaaa tgaattctat taccatgaga tcatcggtct
    11881 gcatgtatta gaagatggaa ctgagttagg taaagtaaaa gaaatcttgt caccaggtgc
    11941 caatgatgtt tgggtcgttc aacgtccgaa aaaagctgat atattgcttc catatatcgc
    12001 ttctgtcgtc aaagaagtcg atttagaagc tggagtggtc cgtgtagaaa ttccagaagg
    12061 actgattgac gatgaagatt gatgtattga ctttatttcc aagaatgttt gaaggtccta
    12121 tgggggaatc catcatcggt aaggctgtag ataaaggatt attagatatc aatatctcta
    12181 acttccgcga ttattcagat aacaaacatc agacagtaga tgattatcca tacggcggtg
    12241 gagcaggtat gctgctcaaa gtccagccca tctatgataa catccaagcc attgaaaaag
    12301 ctgcaccgga tgtcaaaaaa agagtaattc ttcttgaccc agctggtaaa cgattcgatc
    12361 agaaaatggc agaagaattt tcacaagaag aacacttagt attcatttgt ggtcattatg
    12421 agggatatga tgaacgtatc cgcacattag tgacagatga agtttcctta ggagattatg
    12481 tccttactgg gggagaatta ggtgcgatgg tcatgatcga tgcaacagtt cggcttttgc
    12541 cagatgtgtt agggaatcag acttcagctc aaacggattc ttattcaacc ggtttattgg
    12601 aacatcccca atatactcgc ccggcagaat ataaagggat gaaagtacca gaagtattga
    12661 caaatggaaa tcataaattg attgaagaat ggcaattaaa agaatcacta agaaggacct
    12721 atcaacgtcg gcctgatctt ttggaaacac ttgaatggac acctcaaatg acgaaatttt
    12781 tagaagaaat caagaaagaa gaacaagaaa aaacagcaga tgaagccaag tgactttttc
    12841 taaaatcttc tttacagtag gttgataata tgttagtatt ttatggtgag tgcaaaagca
    12901 cttaactatt acgatattcc gctgtgagaa aagctcataa gaatatttgg aataaggaga
    12961 agaaaaccat gaatccatta atcgaagaat taacaaaaga acaattacgt tctgacatcc
    13021 cagcgttccg ccctggtgac actgtgcgtg ttcacgcaaa agttgttgaa ggtactcgtg
    13081 aacgtatcca gttatttgaa ggtgttgtta tcaaacgccg cggtgctgga atcagcgaaa
    13141 cttatacagt acgtaaagtt tctaacggag tgggcgttga acgtacattc ccattgcata
    13201 caccacgtgt tgcaaaaatc gaagtagttc gctacggtaa agtacgtcgt gcaaaattgt
    13261 actacctacg tgcattacac ggaaaagctg ctcgtatcaa agaaatccgt cgttaatcat
    13321 tgttatcaga ctgagaaaga acccttggta ttcaagggtt ctttttttat tatctgtttt
    13381 tttatattaa cgatttctat ttggtacatt tttgattaat aaaaaggggc aaaaaagggg
    13441 caacaagtta cagtttttct atatcttctt tcaatttttc ttttactcct tttgtcacat
    13501 gcaaataaat cttttcagtg atatcactat tttcgtgccc aacgcgatcc tgaatagcat
    13561 acagaggagt tcctagttcc gctaattttg aaatatgggt atgtctaaaa atatgtgaac
    13621 taagtttttt atcaatcttc atgtcagctt tatgatttct caaataggtg ttaattgctg
    13681 ttagttggaa aggagttcct ttcgttgttt gaaatagaaa ttgacccttc ggatttaatt
    13741 ctagaagctc attgtaaata gctatcgctt tttttggtaa atcaatttct cgcattccag
    13801 cagcagtttt tgtagaatca gattttttca tatcagctat tgaacgttct ctatacatca
    13861 tcgtcccatt tataactact gatgcattat tattggtaat gtgtacatcg tctttactta
    13921 atgcgattgc ttctccaggt ctcattccag tcaaatatag ccactggaaa aggagagaat
    13981 atcttttatt gtgtgaagtt gtgaaatcta ctagtctttt atattcatca tcttctaaaa
    14041 acttatcttt aatttttatc gtttttgact ctcgtttata atcaataact acttcgttga
    14101 taggattttt ttctacatag ccttttttca tagcgtatga aaaaagaaga ttcaatttgg
    14161 atttaattac actgacgtac ttatttgaca agtcatcttt atatatcata tcttcaaaaa
    14221 tattatttaa atctactgta ttaataccag aaacgatgta agtctcaggc atcttcttct
    14281 ttatagtgtt taagatatta ttcgtaggat aatatgtaga ctccttaact tgccttttgt
    14341 aaataactaa ccattcttcg acaagctcat gaaatgttag attaggcttc tggagtgttt
    14401 tttcatttag ttttatatca atttttttat ttaactccag taatgccact ttctgagttt
    14461 ctcgagactt atttttataa gtaatgctca ctttttttct ttttctagtt tttggatcaa
    14521 tatatcgttc attatattta tatacttttt ttccgttttt atcagttttg gtttcaatcc
    14581 acattgtttt catctcctat ttgttgctat aataggaatg gataagtaag ccgattatag
    14641 caggtttatt tttcatcacg tccacaaact ttggcgaggg agggggcgtg tttttgtatt
    14701 ttaacgattt atattgaatg ttgattcagc actttcagca actgtactat aatcagacgg
    14761 attatataac actccggttt ttatcgttac ttttgtaata tcgttaactt tagatggatc
    14821 taagtaagct aaactataaa attctttact ttcagttttt ttgaaaaacg agtttgttgt
    14881 cattgtatgc ataagatcgt ctgaactgaa atcaatttgt tggccgttat caagtatggc
    14941 gtgtgcaagc ccattataac cataatctac ttcagaattg tttttaactt tgaatgcaat
    15001 ttgtaaacca taaaaatttc cttcactatc tttgtgatta tttgcatcgt agtaaccagc
    15061 agcgctaggg tcagcataat tggaatactt gagtagtttg atattagata tataaatgcc
    15121 gatatcacca agaggaatat ctgattgtgg gcttgccgtt ccaattaatt caattttgcc
    15181 acttgtatct cttttttctt tggtccattg accaactttg aggagggggc catcaacctc
    15241 ctgtgaattt ttagaagact gtgttgtact ttctgataac gtaactgaag agtctttttc
    15301 gtttgttttg ccagtattat ctacaacatt agattggcta catccggtaa gaaaaaaagc
    15361 accaaatact aaccctaaaa tcactttttt cattctttat tctccgtttc tatgatatta
    15421 tttttatgta ggatcttaga aacgagatct tagtccgtgt tgcagcacgg gcttttttct
    15481 ttataacttt tttagagatt ataggcaaaa tagtaggaca caaaaatata ttattgtatt
    15541 ccgtatttag aaaatcctaa ttgaacttca ccagaagttt tttgctgtgt tgtacgcaat
    15601 gcttcttctt cagacattcc attctgtact ttccatgcaa caggcgacat cccgtatttg
    15661 ttaacaaaat cagtaagtga taaagtgtca gcgtcttgct gaccgcttgt ttgttggtct
    15721 tctggatttt gttgagatgc tgcttgttgt tctttctgat cttgactgat aatattgcca
    15781 gcatcatctg tagtcaatcc attttcataa agggccacgc cgaaagcttc ccactctttg
    15841 ttggaccaat ttgcacgatc agctggagtt gactgtaaag tgcgttgttt catctgttca
    15901 tatgtttctt cttgaggtgc ggtttggatt gtatcctgac tggagcttat aactgttggg
    15961 ctaggttccg ccgtagcttg gttagagctt gtaactgttg aactagaatc tgtcttagat
    16021 gtagatttgc tagtagagga actggtttca gttgtttctt ttgttttact tacttttgtt
    16081 tcttggttag aagtggcatc tgttgattca gcttttttat tatttgaaca agctgaaagt
    16141 agcagagcag tacttaacaa caacataacg ctaacttttt tcattttata attcctcttt
    16201 ctcgttgtaa tatgtgtgct aacacgggct tttttatata agaaaacgat aagcgctttc
    16261 tggaagtccg taaagattct ttaattcatc gatttttttg ggatattgat cattatcttc
    16321 tttataaaga gaaacaatga gattagcagc aaagcaatta gcttcgcttt cagatttgct
    16381 tctagatgtt cttgttgata catagtaact ggataagccg cgatgaaaaa tagcgtgacc
    16441 taattcgtga gcgcaaatgt agaatctttc ctcagagtct cgcagttcat catttaagaa
    16501 gattattgca cgacctctaa tttcttgaaa ctgtcctttg ggattttcga taaaaggaac
    16561 gtattgaatt ttaatgccca tcttttcaca aatataaaaa ggattagcag accggtattt
    16621 ccgcttcaac tcctcgacta aattaatcgt atccatctcc ataagctcac atctttttgc
    16681 ctttttcttt gtcttctttc acaatatccc agaaggttcc aataaggata tcttttacgc
    16741 gttggacctg ttcaggcgtc agtgtttctc cgccataaga catattgaca tttgaatcta
    16801 gtaatttatc aagttcaact acttcatctt ttgttgccca gtcaggaact tggtttctac
    16861 cgagtaaata atcagtagtt acattaaaat aatctgctac aagttgtagt cttttagtac
    16921 taggagttct atttttccat tgataaatcg tgtttttagg tatatttaat tcttcttcca
    16981 attgagttat acttatgcct cttttatgag ctaattcctt tattctatct agtaaattca
    17041 ttttcgcacc tcacaagcta cgaaaacact aataaaaaaa ttagttaaag gtgttgacaa
    17101 ctaataaaat tgttagtata ctgttttcgt aagctaaaat attagctaaa aagacttgat
    17161 aactaataaa cacttcacgg tcggcaaact ctgaaatgta aattactagg catttctgtg
    17221 tcttatttag ctatatctat atactaataa aaatattagt tattgtcaac gaatattagc
    17281 taatttttta gcttacagac tattttttag aaaggagcta tttttatgtc tgagaattta
    17341 gacttaaaaa ttcgagcgga gatgagaaaa agaagaatga ctttcaaaga actagctgcg
    17401 cttgttggta tttcaggagc ttatttatca gatattctaa acggcaatcg tgatggaaag
    17461 aaagcacaac agcatatcga aacagtgaaa aaaatattgg acatccgata gggggggtag
    17521 gcgatgacaa aactaaaaaa acaagatttt gtaaaaaaat acaattattc tccatctact
    17581 tatcaacgtc gaatgtcgga actaaaaaat acagcaattt tctcagcggc gtatgaacgg
    17641 gtcacaggac aagaagtttg gatcaataca gaattatacg ataaattttt gtctttcaaa
    17701 tcctataaca ggttacgcac aagaaagata acacctaaag aatttatcga gaagcattta
    17761 gttgatttat aaaaaacaga acattttgag aggtgaaggt taatgggcaa attcaacaga
    17821 gcgctagtgt tcagcgcacc gctaatcatc tacgctttag gcctctgggg aagcaggcaa
    17881 gcgttgatag gaacgattgt ttacatggtt tggattttta tggggcttga tgaagctgaa
    17941 gctgagtaca gagcgaaaaa gccaaccgag ggggctgact aaaaatgaat agaaaagaga
    18001 aactagaatg tatattacta ttactcagtt taattctttc actaatttct ctattgggaa
    18061 gtttgtattt ttgatatcaa caattttgtg gatttgggtt ctatttagag taaatatcat
    18121 ttttgtttgg tgattaagga gtttattaaa attaattttc cctacttcaa atgcaaggta
    18181 acaagatata gcacttttag gaggaatatt tagcggtaca gcttcagagt atattctatt
    18241 atcatcgact gatcctcctt tagcaattaa tttcttaaat ggagtagctg accatctgcg
    18301 gtttaagtta gcggatgaaa gttctaaatt aactaacata gctggttctg ttgaatagtt
    18361 agaaatgatt acttttgtat aaatcatatc tgcagcgaag taagaagcat taagttcaac
    18421 ttctagttga gggcgcattc cttttatttt tatccctgtt aaaaacgtac tcaatataaa
    18481 acttattatt gacatccatt gaaaaattgt taagtgaaaa aaattcaaaa taaacaccac
    18541 cagtttttaa ctaaattata ccaaaaagga gagaagaaat aatgcaagaa ttagtaattt
    18601 tgaaaaataa agaagctgtg actacgagct tacaagtggc agaaagcttc gagaaaaaac
    18661 atcaacatgt tttaagagat attgatgcac taaaaaaaga tgtgtccaat tttggacaga
    18721 tgtttgtaga aggtaatgaa ccagattcat atggcagaaa tcgacgagtt ttcttcatta
    18781 gtagagatgg atttttcttg ctggctatgg ggtttacagg aaagaaagct atctacttca
    18841 aacaaaaata cattgaagca ttcaacgaaa tggaagatgt tattcgcaag aatactgttc
    18901 ctcaaacaat tgaagatatg atgatctatc aattagaaga aatgaaagat gttaaaaaag
    18961 atgtttccat gcttaaagat actatgcgaa ttagcggaca acaagagttt gaaattaagc
    19021 aaaaaggaaa tatgaaagtt atgggagttc tagggggaaa agaaagccga gcttatgaag
    19081 aaatcagcaa aaaagtattc tcaaaatttt ggtctgaatt taaacgtacc ttttcaatcc
    19141 caagatatgg cgagttacct cgtaagagat tcgatgatgc tgtttcattt attgaaatgt
    19201 ggttgccaga aactgcgatc cgtatggaaa ttgatcaact gaacagacaa cagagacttt
    19261 ttggtgatga caatgaatag agctgaagcg ctaagaatag ggacggcaat tgctaattgc
    19321 tggtggaaat actataaacc aatcatccta agccaacaac atattgacaa gcaaaaagca
    19381 tggcaacaaa taaaaaagtg actccgccgg caagcaaaga gtcacaaaga aaacacatca
    19441 taaggagatt ttagcatatg gaaaaagaac tttccactct agatcaatat ttgattgatc
    19501 ctgattgggg caagccgaaa attgaggaaa caagtggtcg aaaaatcaga cgaaatcttt
    19561 tgacgaatga agaactagct tgggatcaag atgatttagg caaccatgta actatttggg
    19621 atcatgttta tcttatccat ctatcgaagc attcgaataa acctgaatat atttacgtca
    19681 tcgaagatgg cttgattgat gcgctagaag agtacgacag agataacttg attgatatct
    19741 cttattacgg accaggtaag aaatacattg ctgaaatgga ggcagaattt gatgagtgaa
    19801 atcaaaggga caacgaactt tgaaaaactt tttagtcgta agttaaataa aattctcaag
    19861 aaaaaaggaa attttgatta tttatcttgg gctcacgcgt gggagattat gaaaaagaat
    19921 gatccacagg caacggtaac tattaatgag tacaaacact acagggttgt ttctggaact
    19981 catcaagact ttcttgttga ggaatataaa ccttttctta tggatgaaac tgggacttat
    20041 gtatctgtct cagtaacggt taaaggacac acggaaaccg aattatttcc tgttttagat
    20101 tatcgaaacc aaccagttgt taaaccaaat gcaatgcaaa tcaataactc attgaagcga
    20161 tgctttgtga aagcattggc tctacacgga ctgggattat atgtatttca aggggaagat
    20221 attccaacac cacctagaat cgatacaaag aaattaaaca tgctagagac gattctagaa
    20281 gctttcaatg agcagatggg taaagatatg accaaaacct taatcgaata tgttaatgag
    20341 cagacagata agttagggct cttagctgat aacgttgaaa ctattgaaca gttaagctat
    20401 gagcaatgtg ccttgatgga gcgagcaata gcagctaaga gaaaagaatt agataagaag
    20461 tgatatgagt gtttaaacca ttaatcgatt catattcagc ggttctgaaa aagttcaaag
    20521 gaaaagacat aagcgcaacc atcaatgagg aagtgaacat tgatcgacta aagacgatgt
    20581 atgacggcta cgatggtgat cgagttattg aaattcgttt tattgatcct agacgtttca
    20641 cagtacagca acgaaacttc atctatgcac tcataggcga tattttcatc gatacaggca
    20701 tgccaacgga cttctggaag gaattctttt acttccgttt cgaaggtgtc acagggcgcg
    20761 aaataagcct caaagatgaa tcgaatacga ctgtgagtga tgccaatatc ttagcaaata
    20821 tcatcttaga ttttatcttt gaacatcata ttcctttcaa agaaggctat gagattttac
    20881 cagcgaatca agaatattac ttctacaaat gcatcacaaa aagagtctgc tgtatctgtg
    20941 gcaaaacagg agctgatatc gatcactttg acaaagcgct aggaagacga aagcgcaaag
    21001 aagttgatca ttcagagtac acatttgcag cactctgtag aattcatcac acggagaaac
    21061 acaaaatagg tgtgaccaat ttcaaaaata agtatcaaat caaagggatt aagttaaacc
    21121 aggagacaat caagaaatta agaatcgggg gctaatgatg attaatttaa acgcagtagc
    21181 gtttgaacaa acatggcgca ctaagtataa aaaaatgagt ccaagagaca aattgttctt
    21241 agaaatcatg acatttgctt tcattggtac acaagctgaa caaagcgata ttagtgttga
    21301 aaaaattaag acgaatagat tagttaatgg aattacagag acttgttacc agtacacgat
    21361 tatcgtcgtg gatgaggagg aataattttg gcagaaagaa gaatgttcgc aaagacaatt
    21421 attgattctg atgcattcct agatatgcct ttatcgacac aggcattata tttccatcta
    21481 tcaatgcgcg cagatgatga tggatttatt aataatccca aaaaaataca acgtatggtt
    21541 ggttgtggtg atgatgattt aaaactgctt atggcaaaaa gattcatctt agttttcgag
    21601 agcggtgtga tcgtcattaa gcattggaaa atacacaact atattcgtaa tgatcgttac
    21661 aaacccacgt tatatcagga tgaaaaagct ttactagcag acaaagataa caaagcttat
    21721 acatttgcag aagagctttc taaacatgat gaaaaacttg gtataccaga tgacaaccaa
    21781 gcggtatacc aaatggatac acaggttagg ttaggtaagg ataggttagg taaggatagt
    21841 aaagagataa aagatttaac gccttcgaaa aaatcgaagg ctaagcccat ccgtcataaa
    21901 tacggagagt ataaaaatgt tcttttgtca gatgagcaga tggagaaact caaaacagaa
    21961 ttccctaatg attaccaaga gcgaatcgaa cgactgtcag agtattgtga atcatctggt
    22021 aagacttata aaaactattt ggcaactatt cgaagttggg caaggaaaga aaaaagtgaa
    22081 cctaagaacg caagcagtgg atacaagcgc acaggaagac gagagaagct tcctgaatgg
    22141 gcaatcgacc aagaagccta tctcaagaaa aaagcgctag aacgagctaa tagacaatca
    22201 aaagcaccat tttaagaggt ggaaaattga aaatcgatta tctagaacta attaatgaaa
    22261 tagcaaagta taaaactggt gaggaaatag aaatcctgag agacgtatat gatcaactcg
    22321 aagaagctgg aatcgaagga attaataatg atcgttcgag ttggagtaaa ctcagatact
    22381 atttcgcact ctatatcgat acaacacaat taagaaattt agcttataca aaattactat
    22441 ttgttgattg cgttaaagga ttgcaaaaac atcttagtga acttgagcag gtgtaatcag
    22501 atggatctaa aaacatttac agcacagatc gaactaatgc atcaagaagc tttaagacaa
    22561 agcgcctcgt acgaagacaa gtggctcaac acgttccatg gtggacgtga gagcgcactt
    22621 gatcaagtac tcaaattatt gaaaggggaa cgtcgggatg gataagaaag cggcaatgaa
    22681 acgaatcatt gaactgacgc attctgaaag ttggcaggaa gatgaagaag tggttgctga
    22741 agttcagcga ctaggaaaga tcgctaatgg acgtatacga aaaaagccag acaaaagaaa
    22801 acagcgcaaa aggaaaatcg tcgttgtttt acacgaaggc aaaattttga tgcaaggaac
    22861 agctagtgag ctgtctgcag aaactggata tacgcgtggg actattcgaa cgtacgcttg
    22921 gcgaaatcac accgatcgaa aagggcacga atataagtat ttggaggaag aataatgaac
    22981 gaaaacaaat taatcaaatt gggtgtagca ggagcagtaa tcgtaggtat tggagttatc
    23041 ggaggattta agttcttcga aaaaatcgat aatggatatg tgggtgtgcg ctattcaatg
    23101 aacggcggta tcaaagatga agcactgacg caaggtgtga aatttgtagg gattgacaaa
    23161 gtgatccaat atccaattcg cttgcaaact atccaatcaa aaaatatttc agtatctaca
    23221 agcgacggca aaaagacaac gattgatatc aaatatgact acaaagttga ttcaactaaa
    23281 gcagcaaaaa tgtacaagga atttgggaat atcacttcgg aagatatcga aagtggatgg
    23341 ttaaaatcta agcttcaaaa ggtcgctcgt gaagtttatg cgaaatatag tctgcttgat
    23401 gtcctttcag gagattcctc taaagttgaa gctgaggtat taacgaactt tgctaaatca
    23461 gttgaatcta aagggtttga agtcgaagac gtaacacttg gtgttccaga tgtcgataaa
    23521 gaaacacaaa aatcaatcga tgcgatcatt cgagctggtc aagaaaatga aaaagcgaag
    23581 ctagatgcag aaactgcaaa aactcaagct gatagtgaag cttacaagaa aacaaaagct
    23641 gcagaagcag aggcagaatc taatcgcaaa gtcgccgaat cagtaacaga caatttgatt
    23701 cgttatgaag aagctcaagc tcgcaaaaag catggatggg taacagtaaa tggagcagat
    23761 actgtagtta cggatgaagc aggcaaataa tatgggattc tttatggcta aaattctctt
    23821 gttcttaggt ttagtaggag cagcatatct cgtgtatgcg ctcctttccc aaactgatga
    23881 caaagaagat gacaacaacg atgaaatgaa attttaggag gagaaataat ggatctcatt
    23941 acacaataca gtgatatcat cctcaagaaa atcatggcaa agattcagaa agataaaaaa
//
LOCUS       DAFENC010000039        23827 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.041, whole genome shotgun sequence.
ACCESSION   DAFENC010000039
VERSION     DAFENC010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23827
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.041"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(53..787)
                     /locus_tag="LP493_002039"
     CDS             complement(53..787)
                     /locus_tag="LP493_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBL2134184.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1114..1524
                     /locus_tag="LP493_002040"
     CDS             1114..1524
                     /locus_tag="LP493_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBL2134185.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1517..2218
                     /locus_tag="LP493_002041"
     CDS             1517..2218
                     /locus_tag="LP493_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBL2134186.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2218..3804
                     /locus_tag="LP493_002042"
     CDS             2218..3804
                     /locus_tag="LP493_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2134187.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3823..4044
                     /locus_tag="LP493_002043"
     CDS             3823..4044
                     /locus_tag="LP493_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HBL2134188.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4041..4802
                     /locus_tag="LP493_002044"
     CDS             4041..4802
                     /locus_tag="LP493_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HBL2134189.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5182..5691
                     /locus_tag="LP493_002045"
     CDS             5182..5691
                     /locus_tag="LP493_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBL2134190.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5766..6305)
                     /locus_tag="LP493_002046"
     CDS             complement(5766..6305)
                     /locus_tag="LP493_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HBL2134191.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="LP493_002047"
     CDS             complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="LP493_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HBL2134192.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7318..8169
                     /locus_tag="LP493_002048"
     CDS             7318..8169
                     /locus_tag="LP493_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBL2134193.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8197..8832
                     /locus_tag="LP493_002049"
     CDS             8197..8832
                     /locus_tag="LP493_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBL2134194.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8852..9625
                     /locus_tag="LP493_002050"
     CDS             8852..9625
                     /locus_tag="LP493_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL2134195.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10033..10830
                     /locus_tag="LP493_002051"
     CDS             10033..10830
                     /locus_tag="LP493_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HBL2134196.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10808..11221
                     /locus_tag="LP493_002052"
     CDS             10808..11221
                     /locus_tag="LP493_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBL2134197.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11205..13850
                     /gene="mutS"
                     /locus_tag="LP493_002053"
     CDS             11205..13850
                     /gene="mutS"
                     /locus_tag="LP493_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBL2134198.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13868..15976
                     /gene="mutL"
                     /locus_tag="LP493_002054"
     CDS             13868..15976
                     /gene="mutL"
                     /locus_tag="LP493_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HBL2134199.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRQTGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15998..16558
                     /gene="maf"
                     /locus_tag="LP493_002055"
     CDS             15998..16558
                     /gene="maf"
                     /locus_tag="LP493_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HBL2134200.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16643..18631)
                     /gene="treP"
                     /locus_tag="LP493_002056"
     CDS             complement(16643..18631)
                     /gene="treP"
                     /locus_tag="LP493_002056"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HBL2134201.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18854..19567
                     /gene="treR"
                     /locus_tag="LP493_002057"
     CDS             18854..19567
                     /gene="treR"
                     /locus_tag="LP493_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HBL2134202.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19644..20090
                     /gene="msrB"
                     /locus_tag="LP493_002058"
     CDS             19644..20090
                     /gene="msrB"
                     /locus_tag="LP493_002058"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HBL2134203.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20260..20862
                     /gene="ruvA"
                     /locus_tag="LP493_002059"
     CDS             20260..20862
                     /gene="ruvA"
                     /locus_tag="LP493_002059"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HBL2134204.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20875..21876
                     /gene="ruvB"
                     /locus_tag="LP493_002060"
     CDS             20875..21876
                     /gene="ruvB"
                     /locus_tag="LP493_002060"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HBL2134205.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21905..22483
                     /locus_tag="LP493_002061"
     CDS             21905..22483
                     /locus_tag="LP493_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL2134206.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22535..23017
                     /locus_tag="LP493_002062"
     CDS             22535..23017
                     /locus_tag="LP493_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HBL2134207.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23134..23508
                     /locus_tag="LP493_002063"
     CDS             23134..23508
                     /locus_tag="LP493_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134208.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7781 a         4286 c         5115 g         6645 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatatac caaaaaaaaa acgttttttt
     1021 tctcaaaaat tgtatcttag aaacagcatg ttttgaaact ttcagaaaag gtttgttagt
     1081 aaaatgaaag ctatacgtaa ggagtgttgt ttgatgaaat tttttcaaga gtttttcatt
     1141 attattttct tttctgtatt aggagaaggc atacggattt ttgctcattt acctattcct
     1201 ggaagtatct taggtattct ttttttattt ttagcatttg aaatgcatct tgttgatcct
     1261 gaaaaaatcg gagcaactgg tgatttttta ttgaataatc tagccatttt atttgttcct
     1321 gctggtgtag gtttattgga atattttgat gatattgctt cgatatggcc tgttttactg
     1381 ggagcagtcg tcgtgtgttc catcgtcacg atggttgcag cgggaaaaac ggcagaaggt
     1441 gtagaagctt tgctgggcta tgtccgtaag aaaaaagcag aaagggtatc tgtaaacgaa
     1501 atggaggaga atcaaattga ctgagttttt tgtgaatcca ttatttggct taagtttgac
     1561 tttaggagtg tacgtattat ctgacaaatt tttgcggaaa tataaactgc ctgttttgaa
     1621 tcctctcgta ttatcgattg ttgttattat cttatttttg catttttctg ggatcagcta
     1681 taaagactat aatatcgggg gcaatttttt gactatgctg attactcctg cgacagtggc
     1741 acttgccatc cctctttata aaaacttccg tttactgaaa gagaattttt atcctgtaat
     1801 ggctgcgatt ttagcaggaa tagtcgcaaa ttgcttggtt agtgtagggt tcggttactt
     1861 cttctctctt cataaagaga tggtgatctc attactacct aaatctgtaa cgacggctat
     1921 ttctgtcgat ttatctcata cgatgggcgg ggtgaatgcc gtgacacttg ctattgttgt
     1981 ctctacaggt atttttggtt cgctgatcgc cactcatatt ttccgcctat tcaagatcga
     2041 aagtccagtt gctcgcggtg tggcgttagg aagtacttct catgctattg gtacagcaaa
     2101 agcaatcgag attggtgaaa tagaaggaat catttccgga cttgcgatat gcgtcaacgg
     2161 aatattgacc gttttattgc taccgttatt ctttcagcct tttgctggct tgttttgatg
     2221 cgaaaaccac tattttatgc tacaataacc aaaacgttcg agcataaaaa aggagggaaa
     2281 gacgtgtatt tgtcttccga gtatcttaaa caatttgata aagatctata ttataagatt
     2341 ctcctcctag aaagttttga ggatcaagct tggcataccg ctgcacaatt agcgcaagtt
     2401 gttcagctgg atgcccgcag cgtgtcgaaa tacctgaacg agctgtctaa aaactatcag
     2461 cagtttagcg gtaagacaca ccctttgttt acaaaaaatc accgttctgg ttataacttt
     2521 tatgatacgc tcgattcaat tgaacatgag cgttttttga tctatctcgt gcaaagtacg
     2581 ctgaaattcc agttgctgca cgacattttt tttgaagaat tccatacaat gtaccaattt
     2641 gcgcaaaagc attacattag tgaatctact gctcatcgaa aaatcaatga atggaaacag
     2701 caactgcaaa cttacggaat tcggctgcaa cgaggtacat atatcgctca aggcgaagaa
     2761 gaaatcattc gactttactt gcatatgaca ttctggcagt tgtttcgagg gaaaatctgg
     2821 ccatttgaaa cgatttctca aatggacgta aagaatatgg cagaacatat catggctttt
     2881 tttaatgttc gtctgaacga gatcaaaaaa agacgattgg aatatatgct aggtgccttt
     2941 tttttaagaa aatcacagaa gcattatgtt gtattgaatg agaaaaaaag acggctgatt
     3001 tctgacaatc tgttgttcca gcgattttgc caggtcatgg agccggtatt tcctaattat
     3061 tttcaagtag aagacgagtt aggcgcatta tttcttgtac tgatgactcg tgaagaatat
     3121 tatagtgatc ctaagatacg gaagaaaatt tttgattttc atcaacaagc aaaaacaccg
     3181 ccctttacag ccctttcaga agcaaaagcc gctctttctc tttatcagga agagcagggg
     3241 ctgccagcag aaaatctaac cttcgaggca gaaaactatt tattcagcag tcattttttc
     3301 gcctatcttt ttcctaatgc gaaagaaacg attgatggca atagtagtga ttttattaat
     3361 catttagtta ttgaaaacaa ggaattgaaa caatggctcg tacatttttt tgaaagtaga
     3421 cacaaacatc ccaatcatct ggcatttaaa aatcatgcgt ttttgatggg gcggtatctg
     3481 actgtgttta aaacattagg agcctttact ccacagcttc caaagatcac gatcctttta
     3541 atgacagatt tcccattatt tgaagagcaa ctgttagagg agggattacg gacatttttc
     3601 cgtaatgagt atcagctgat ttttctgcca acagattatc gggggagaga agttgatctt
     3661 ctgatttcga caagtaaagt ccaccgcaaa ccatgggcgg atcttgacta ttttattgtg
     3721 actgaagaac taaaattaat tgattacatc caactatctc aaaaatttga aatgattcaa
     3781 aaacaaaaac tattaaaaca ataacaaaga aggagaaaaa agatgacatt tgaagaaatt
     3841 ttaccagaat tgaaaaaagg tgcaaagatt attcgtaaag gatggagtgg atttgaactt
     3901 tatgttgttc tcgtatccga tgatgaattt gatggctgtc cggtgacgcc gtacttattg
     3961 atcaaaacaa gtgacgaagg tttttccagc ttcgctccta cagtttgtga tattttagca
     4021 gatgattggg cgatcgtaga atgaaaaacc agtatccaga tctagctaaa caggttgtat
     4081 ttatcacagg agctgcttct ggaattggtg ctgcgcaagc ccgagcgttt cttgaacaag
     4141 atgcttttgt atttggatta gatcaaaagt tcggtaaaat ggaagaaatt tctttgcgat
     4201 ttcctgaaac ttttgcctac gcactaggtg atgttcgaca aatgaaagaa ctccaacaag
     4261 cggtatcgaa atgccaaaat cattttggtg aagttacgat tttactgaat acagcgggga
     4321 tattggatgc ctacaaaccc ttgatggaaa ctgacgaatc gctgtgggat ctgatttatg
     4381 agacgaatgt gaaaagcatg tatcagctga caaaaatcat ccttcctgat atgatccgcc
     4441 aaaaaagcgg aacgatcatc aatatggctt cgattgctgg cttgattgct ggtggaggtg
     4501 ggatcgctta tacaagcgcg aaacatgcga ttgtcggatt taccaaacaa ctcgctctgg
     4561 attacgcagg acagggtatc cgagtaaaag gaattgctcc aggagccatc caaacaccaa
     4621 tgaatgcggc tgattttgaa gggaaaggtg agatggcaga gtgggtggca aatgaaacac
     4681 cagtcaagcg atgggcacag ccggaagaag tagctgagct gacgttattt cttgcctctc
     4741 ctcaagcaag ctacatacaa ggaacgatca tcccaatcga cggcggatgg ttgttaaaat
     4801 aaccttgtgt ttttttcaag cttctgtatg ataaaactaa agagagaaac aacggttgat
     4861 gataaaaaaa gtcgatgact gttcccgaca ttcgatgccg aacagccagt tcaaaaaatt
     4921 ctttttaata atcgttaata ttcgaaacta agcggctttt cacgacctct tgatataaac
     4981 gatattcaaa agcttgcaac tgcggtaaca agtccagcca aatgaaaaat ataaggagct
     5041 atttttattt gaccattctt attacttgtt gcagggcagc tttttcacta ccttctgcga
     5101 cacttcagtt ggaattttct tcccatcctt tggtcgcggt cattaccaag ataaaattat
     5161 cttgcaaagg agaaatagaa catggaaaaa aataataccc gttcagccaa acgctggaca
     5221 acgacagatg tgactcggat ggcgctagtc actggtttat atgtggcagt gacgctggtt
     5281 ttgtctgtct ttagctttgg agtgattcag attcgtctct cggagatgtt caactatctg
     5341 tccttgtata acaaaagata catcgtcgcg gtaacagcgg gagtagcttt ggctaatatt
     5401 gcttctcctc ttggactgat agatgttgca gtaggaagcg tcagcacgct gcttgtattg
     5461 cttatcaact ataaaatcac tagtcgcatc aaaaacatga aaatcaaaat ggccgtgaca
     5521 gcatgcgtat ttgctttttc catgtttaca gtagctggtc agctaacgat tttatatcaa
     5581 ctaccttttt tcttgaattg gtgggtgatt gctttaggag aattggcatc aatgattgtc
     5641 ggtgggataa ttatttattg gatcggtaaa aaagtggatt tgtcaaaata aagatctgtt
     5701 taatttaaaa tagggcagca tggaagagac tgaatgttga gtcttcttcc atgctgcttt
     5761 tttgattaat ttgtatgaag aaatcgattt agccgttttt tcatcaagat accgatataa
     5821 gctgctccag ttgccttgat tgcttccggc agtaaaaacg gcagtagtcc actggcaaat
     5881 gcagttgtaa aagtaagatc accacttatt ttcagccaga tcgttccgca gatcaatgca
     5941 gcaagagagc ccattagatt ggcaaagatt gcatataagt aatgagcatc cgttctttcg
     6001 atcatccaac cagttatcca cgtttgtaag agaaatccaa tcaaatatcc gccagttggc
     6061 ccaaataaaa cagctatacc tccagtcatc cctgaaaata caggaagacc aatcaagcca
     6121 agtaaaagat aaactccaac agatatcaat cctagttttc ttccgagaaa agttgctgtt
     6181 aatccaatag caaatgtttg ccctgtcaaa ggaaccaaac caaaaggaat ggtcatctga
     6241 gaaaggacag aaataatcgc ggcaaattcc gcagcaagta tcaattcttt caatgttcgg
     6301 ttcataacgc cctcttttcg ttaacttaat atttttattt ggttaacgaa attgtaaaac
     6361 aaagtgatta ctttgtaaat agaaaatata aaaaaagacc agctatccaa tagatagcgg
     6421 tctttttcaa gaaagctttt gaaattataa gctttggttg tagtattcaa cgacaagagc
     6481 ttcgtcgatt tctggatata gttcgtcacg ttctggtaaa cgagtcaatg aaccttccaa
     6541 tttttcagcg tcaaagctta cgaatgctgg gcgtccaaca gttgcttcta cagcttcttt
     6601 tactgttacg atgttttgtg atttttcacg aactgagatc acttgaccca cttctacgtg
     6661 gtatgaaggg atatcaacgc gtttgccatc aactaaaatg tgaccatggt taactaattg
     6721 acgtgcttga cgacgagtcg ttgcaagtcc taaacggtaa acaacattgt ctaaacgttg
     6781 ttctagtaag atcatgaagt taacaccatg tttaccttct ttgattttgc tagcttttac
     6841 gaacaagtta cggaattgac gttcgttcat tccgtacatg tgacgaagtt tttgtttttc
     6901 agttaattgc atgccgtatt ctgattgttt gccacggcta ttaggtccat gttgacctgg
     6961 tgcgtaaggg cgacgtgcta attcttttcc tgtgcctgac aatgagatgc ctaagcgacg
     7021 agaaattttc catgatggtc ctgtataacg agacattaaa atttcctcca atgaatataa
     7081 gtttttggag taaaataatc cgttgaaaaa ttcataatca tatagtttgt tcttcaatct
     7141 tcacctttgc agccgcggtt acacaatcga acccgagacg gggcaacaaa ctagggatga
     7201 gttattattt ttctgctgca ttattttaca caaattacag tatatgatag atcatccacg
     7261 aatgtcaaga taattagtac ataaaaacgc tttacaaacc taggctgtct ttataaaatg
     7321 agagggtatg tgcaaatgga aaaaagcgaa ggaagtttaa ggagaaaatc aatgaatccg
     7381 gtatcaccat tatttgagaa aatcgatgct tcaattgaaa agaaggcgaa tctttttgaa
     7441 aacagctttt cacgttacgc tgttcgagcg gttctcgcct gtttgttttt gactttagga
     7501 acggctgtgg catttgcgat cgcgatgaag ggggaagata tcgcgcatgg tctaggaaag
     7561 attttatacg catttatgtt cagctggggt ctggtcatga ttctatacat gaacgccgaa
     7621 ttaggaacat cgaatatgct ttatatgacc gtgggtgttt ttcggcagag acttgcttta
     7681 agtaaggcag ccaagattct atttgcctgt atttttttca atatgattgg cggtatatta
     7741 tgtggatttc taatttctat gactacgcca tttcaagatt taacgttgga caactttatg
     7801 ttagaatcaa tagcagtaaa actagcaaaa ccttcagcaa cgattttggt ggaagggatg
     7861 tttgcgaata tcgttgtcaa taccgctgta ctgatcagca tgcggatgaa agaggatgtc
     7921 ggaaaagtga tcacagtcgt attcatcatt ttcatttttg cttttttagg atatgaacac
     7981 gtgatagcga attttcctgc ctttacgctt acttactttg cttctcacgg acagatggat
     8041 ggaatgacag tcagcaatgt gttacataat ttgttttttg ctttggcagg aaattatatt
     8101 ggtggcggtt tagtaatggg actgggatat gcttggctga atcagtcaaa atcatcctat
     8161 gtggactaaa aagtcgttca ttaaagggga agtgccatgg aagttttagt ttttccaaaa
     8221 aatgaggaaa aagcgttaca aatggaaaag tacatgaaaa atcttttttc ctttgctgga
     8281 gtacctaagc cggaacgcgc tcttttacaa caaccgttac tggatgagag caaaaattta
     8341 tctatttctg aagttttagc ttttgttcat tattattatg aacaaatcga aagagagtat
     8401 cagtatgtag cgatcgattt agtccagaaa aacatcaaac ggcttacatt tgaagactta
     8461 gtcgtattgt tgccactagt tcagaaaaaa gaatggtggg acagcatcga ctcttggaga
     8521 aaagtataca gcacatggtg taaagcctac ccagagcagc gtgaagaagt ctttcaattg
     8581 tttgaaaaaa aggaagattt ttggctacgt cgaatagcaa tcacgttgca attaggttat
     8641 aaacagcaaa cagacacagg actattgatc cgagcaatag acgaagatcg tcaaacaaag
     8701 gaattcttta tccaaaaagc aattggttgg gcattacgcg attatagtaa gaccgatgcc
     8761 gattgggtaa aaagacagct gacaacagat ttgagtaagt tagctgttcg agaggcaagt
     8821 aagtatttat aagaaagcga gacgacaaga gatgagacgc aaattatttg cttttgatat
     8881 tgatggaacg ttgttagatt caaacaaaca agctttagat agcacaagag aagcattgga
     8941 aaaattacgc aaagccggtc atctggtcac gattgctaca gggcggagcc gatttcatgc
     9001 gcaagagatc attcgcgatc ttgattttac gaactacatt ttatgtaatg gagcggccgg
     9061 ttttttagac catgaacaag tatataagaa tttactagat cgcgaccagt tggatgcgtt
     9121 cgttcaagaa gcgcatcatg agcagatcga tacagctttt gtcagcttag acaatatcaa
     9181 gcgttcttct tccaatgatg taacggtgat ggaagaagcg atgcattctt tcggtgctgt
     9241 cttgcctgaa ttagatcagt tttttgcaga ggaacaagaa atataccaag cgttagcatt
     9301 tttcgatcaa acatatgatg ggaagttctc ttcatatgat aaaattcgat ttgtccgctg
     9361 gcatgagaac agtgtagatg tcgtacctaa aaatggttct aaagcagcga caattctgca
     9421 cttagcagaa caagtaggca tccctcatga agacatcatc agctttggcg atggacaaaa
     9481 cgaccgtgaa atgttgcgca tgtcaggaat tgggatagct atggggaatg ctgtgccaga
     9541 agtacaagca gaagctaaga tggtcactga tacaaacgat caggatggaa tttggaaggc
     9601 attgaaagag ttaagcgtga tttaaaagag gttgtgaaaa agctgttctg catcaagtaa
     9661 taagcccagc caaacaaaaa tagctcctcc tatttttcgt ttttctgggc ttattaccgc
     9721 agatgcaagc tttcgaacac cgtttaagga agaggtcgtg acagaagtgg tcagtttcaa
     9781 gaaataagaa gggatttacg aaaattgctt ctcaaatttt tgtaaaatta cggcttattt
     9841 ctgaagaagt agatgaaaca acgtttattc gggaaatggg actgtgacaa gatgtttgtc
     9901 atagtcccat ttttttattt tatttttcaa aactaagaaa taccaggaaa gagttccttt
     9961 tgtttgacct tttctttctt attgaaaaca actataatat agagtgatgt taaaagagaa
    10021 gaggaattta gtgtgcgggt attgtttatt ggtgatgtag taggttcaat gggacgagag
    10081 atgattactg aatatcttcc tagattgaag aagaagtacc gtccgcaagt aacgattgta
    10141 aatggtgaga atgccgcttc tggacgtgga atcacagaaa aaatctataa aaaatttttg
    10201 caagacggcg tagatgtcgt gacgatgggg aatcatacgt gggacaaccg cggaatcttt
    10261 gagtttgtaa atgaagctaa aaagatggtt cgtccggcaa attttccgga agggacgcct
    10321 ggacaaggga tggtctttgt caaagtgaac caagtcgaac tggcagtgat caacatgcag
    10381 gctcgttctt ttatggtgga cttggatgat ccttttcgta aaatgaatga gctggtagaa
    10441 gaagccagaa aacgtacgcc gatcattttt gtagattttc atggagaaac aacaagtgaa
    10501 aaacaagcaa tgggctggtt tttagatggg aaagtttcag cagtggtcgg tacacataca
    10561 cacgttcaga caaatgatgc gcgaattttg ccaagaggaa cagcgtatct gacagacgtt
    10621 gggatgacag gtccctatga tggtattttg ggtatgcgca gagaacctgt aatcgaaaag
    10681 tttctgactg cattaccaaa acgttttgaa gttgtggaac aaggccgatc gattttaagc
    10741 ggctgtatct tggaattgga tgatacgaca ggtcatgcaa aagaaatcca gctgattcag
    10801 atcaacgatg atcgaccgtt catggagtag aaagagaggc agttttttgc agcaggagcc
    10861 ggaaattcaa aaagaagtaa ggaaactgac aaaactttta agagagaatg aaacgatcat
    10921 tcgctacaaa gaacttgaag aaaagatcca gcaaaaccag tatttagctg agttgagaga
    10981 aaaaatcaaa caagcgcaaa aagatgctgt tcattttgcc cactatgaca aaccagcagc
    11041 agaaaaagaa gcaatcaaac aagcggatca attcatgcaa gaatttgatc agcatccgct
    11101 tgttgtagct tatagaaaac agctgttgga agcagatgat ctgcttcatc atttaacaac
    11161 tatgatacaa gaagaaatca atggacaaat agaggaggaa aaacatgcct caaaaaacta
    11221 aaaatactcc tatgatggaa caatatctaa gcatcaaggc ccaataccaa gatgcttttt
    11281 tgttctatcg tttaggagac ttttatgaac tattttacga agatgcgatc aaagcgtcac
    11341 agcttttgga attaacgttg acgagcagaa atcgaaatgc agaagaacct attcctatgt
    11401 gcggtgtacc tcaccatgca gcacaaggat atatcgatgc cttgattgaa aaaggctata
    11461 aagtagcgat ttgcgagcag gtagaagatc caaagacgac taaagggatg gtcaagcgcg
    11521 aagtgatcca gctagtcact cctggtacag tcatggacag caaaggattg tcggcaaaag
    11581 acaacaattt tttaacagct gtagttagtc aaggaaatga atttggcttt gcttatgccg
    11641 atttaagtac gggagaattg aagacggctc ggttgcatga tgaagaagct gttttaaatg
    11701 aagcctctgc attgcagaca aaagaactcg tattaggcag tgagatcact gatacccttc
    11761 gtgaacagct aagcgggcgt ttagggctag tcttttctca acaaaatgag atggaagaaa
    11821 acgcggaatt tagctttttg acaagcgaac tagtcgatcc gctggaaaaa gaagcaaccg
    11881 gcaaactatt gacttattta tcggtgacac aaaagcggag tttagctcat atccaaaaag
    11941 cagtagaata ccaaccagat cattttttga aaatggatta ttattcaaaa ttcaacctag
    12001 aattaagcca atctattcgg actgggaaaa agcacggcac tcttctatgg ttgttagatg
    12061 aaacaaaaac agcaatgggt ggccgtttac taaaacaatg gctagaccgt ccgcttatcc
    12121 aggcaaaaca aattaaagca agacaagaaa tggtcgcttc tttgctagac agctattttg
    12181 aacgtatcga tttgcagtca gcattaacga aagtctatga tctggaacgc ctagcaggtc
    12241 gagtagcttt cggtaatgtc aatgggcgag acttgatcca gctgaaaact tctttagaac
    12301 aagtgccaat gatcagaggg ttgattgaag gaatcgatca aggtcaatgg caaagtctgc
    12361 tttcagaaat gcagccgatg gaccatctcg tccaattgat cgaccaagct atccaagatg
    12421 atccgccgtt acaaataacg gaaggaaaca tcatcaaaga tggattcaat gagcagctcg
    12481 atatgtaccg ttctgctatg agaaacggaa agaaatggtt ggcagaactt gaagcaaaag
    12541 agcgtcaaga aacaggaatc aagaacttaa aaatcggatt taaccgcgtt ttcggttatt
    12601 atatagaaat tacaaaagca aatcttggaa atgcagaact ggagaagtat gaacgaaaac
    12661 aaactttagc aaatgcagag cgtttcatca caccagaact aaaagaattg gagacacaaa
    12721 tcctcgaagc agaagaaaaa tctgttgatt tagaatatca gttgttttta gctgtgagag
    12781 aagaagtcaa aaaggctatc cagccgctac aagtacttgc aaaagcaatc agtgcagtag
    12841 atgtgctaca aagttttgca acgatcagcg aacgctatca gtatgttcgg ccagaacttg
    12901 tcagtgacaa gcatcagctt ctgatcaaag acggacgaca tcctgtagta gaaaaagtat
    12961 taggacatca ggaatatatc cctaacagcg tagaaatggc agaagacgaa atgatcttgc
    13021 tgattacagg accgaatatg tctggtaaaa gtacgtatat gcgacagttg gcattaactg
    13081 ttctgatggc gcaaatgggc tgtttcgttc cggcaaaaca agcagtttta cctatttttg
    13141 atcggatttt tacccgaatt ggtgcaagtg acgacttaat tgctggacaa agtactttta
    13201 tggtagagat gatggaagcc aatcaagccc tgcgttatgc tacgccaaac agtttgattt
    13261 tgtttgacga actagggcga ggaacagcaa cctatgacgg aatggcgttg gcccaagcaa
    13321 tcatcgaata tatccatcgt catgtacaag caaaaacact cttttctact cattatcatg
    13381 aactgacggt acttgagaaa gaacttccgc agcttaaaaa tgtccatgtt ggagccgttg
    13441 aaaaagacgg agaagttgtc ttcttgcata aaatgatgga tggacctgcg gataaaagct
    13501 acggcataca tgtggcaaag atcgcaggat tgccttccaa tctactagaa cgagcagcag
    13561 atatcctgca tacgctagaa aatggcgata acggacacca tactgttcca gctgaagtag
    13621 aagagaaaac taaaacagcc aaacaggagc aaataaaacc acctgcagaa aaagtaaatc
    13681 aagaccatat acaagaccgt gtaaaagaag aaaaccaaca gctttcttta ttcagtgaat
    13741 tatccgaaaa tgaaacagaa gtcattgaat cactgaagca aataaattta ctagaaatga
    13801 cgccaatgga tgcactaaac acattatatg aattacaaaa acaactgtag gaagaaggcg
    13861 gatatcgatg gccaaaatcc aagaattatc tgaacgttta gctaatcaga tcgctgcggg
    13921 agaagtagtg gagcgaccag cttccgttgt gaaagaatta gtggaaaatg caattgacgc
    13981 cggcagtact cagattgata tcttagttga agaagcggga ctgcggacga tccaagtgat
    14041 tgataacgga gaaggcattt tggcagacga cgtagagaat gccttcaagc ggcatgcgac
    14101 aagtaagatc cataatcgcg acgatctttt tcgcatacga acgctgggct ttcgagggga
    14161 agctttgcca agtattgcct ctgtttctga aatgactctg gaaacggcga atcaggaaga
    14221 aaaacaaggc acctatctgt cgctgaaagg cggagaagtt attgagcatc gaccagcacc
    14281 actgcgtcaa ggaacgaaga ttaccgtcag caatctgttt ttcaatacgc cagcccgctt
    14341 gaaatacgtg aaaacactgc acacagaatt agcgaacatc ggggacatcg tcaatcgact
    14401 ggcattgagt catccatcga ttgcttttcg tttagtacat gatggaaaca aaatgctggc
    14461 aactgctgga aatggcgatc tgaaacaaac aattgcggga atctacggat tatctaccgc
    14521 aaaaaaaatg ctgaaaatcg aaggaaaaga tctagatttt gagttatttg gctatgtttc
    14581 attgcctgag gtgactcgtg ccagtaggaa ttacttatcg acgatcatca atggacgttt
    14641 tatcaagaac ttttccttga ataaagcaat cgttgcaggt tatgggtcaa aattaatggt
    14701 cggtcgtttc cctattgctg tattggaaat caaaatggac ccgcttttag tagatgtaaa
    14761 tgttcatccg acgaagcagg aagtccggct gtcgaaggaa aaagaactaa cagagctaat
    14821 tagtaacgcc attcaaaaag cattgtctca agaaaatctg attccaagtg cagcggataa
    14881 tctacggttt aagaaaaaag tacctgatca gcctaaaaca gaacaaatcg aaatcgattt
    14941 gtcctacgct tttgaagaag aaaaacctaa aaagccaagt agtttgaatt ttgatcgaca
    15001 gacaggtacc tttttcgtag aagaactaaa gaacacattt gttgacagaa ttgttgataa
    15061 gtctgtggaa aatgttgaaa actattctgg tttttctgaa gaaaacacca cttatccaga
    15121 aaaaacagcg aaaacggtgg ataagtttgg tgaaaatgtt gataactttg tagaaaaaac
    15181 agtggaaaaa tctgaaaaga aagaatttcc cattgtggat aacatggaga aaacaaatga
    15241 agaacaagca gataaatccg tagaagagga tgaaaagatt tacgaggaag aattgacact
    15301 ccatcctgaa tttgatttca ctcaaggaaa cgacaaaaca ttagaacaag ccatcaagaa
    15361 attagaaacg gaaaaaccag tacaacgttt tcctcagttg gaatattttg gacagatgca
    15421 cggaacgtat ctttttgccc aaagtagcga tgggttgtac atcattgatc agcatgctgc
    15481 ccaagagcgc attaagtatg aatatttccg ggaaaaaatt ggggaagtat ctgatgatct
    15541 gcaagaattg cttgttccat ttgtgttaga ctatccaaac agtgatgctt tgaaattaaa
    15601 agagcaaaaa cacttgctag aagatgcagg gatttattta gaagaatttg gtcaaaacag
    15661 ctttattgta cgggcccatc ctacttggta tcccaatgga gaagaagaat cgattattcg
    15721 ggagatgatc gatatgctgc tgacaactgg aagtgtgagt gtaaaaaaat tccgtgaagc
    15781 aacagcaatc atgatgagtt gcaaacgatc gattaaagcc aaccattatt tgaatgaagc
    15841 acaagcacgt gtgctgctga aggatctggc acgatgcgaa aatcctttca attgtcccca
    15901 tggccgtcca gtattgattc actttaccaa ttcggatatg gaaaggatgt tcaaacgaat
    15961 ccaagacccg cattaagtca aagagaagag ggaaaacatg aagattgtat tagcatccca
    16021 atcaccaaga agaaaagagt tattggctca tatcgtttca gaattcgaga ttgaacctgc
    16081 tgatatcgat gaaacgccat ttccagacga acagcccgtc gattatgttc gtagaatggc
    16141 tgaagaaaaa gcacgaactg tctgggaaca agatgaaaaa gaagaccatt tagtgattgc
    16201 cagtgacacg actgttgttc tcaatcaaga gatcatgggt aaaccagaag atctggctga
    16261 ggctgaattc atgctgaaaa aactaagcgg ggaaacacat actgtatata cagctgttgt
    16321 tttaaaaaca aaggaacgag aagaacggat actagcagaa gcacatgtca ctttttatcc
    16381 tttgacagac gaagagatca aacgctactt ggagacgggg gattatgcgg ataaggcagg
    16441 ggcatacggc atccaaaatg ctgcgagtgt attcgtcaaa gaaatttctg gagattatta
    16501 cagtatcgta ggatttccga ttggtgctgt caatcaggca ctgaaaacat tcatttaaac
    16561 aaaaaagcgg actatctgat tttcgattga aaatccatga tagcccgttt tttttattga
    16621 aaagattact tatctactct gactaagatt ttacttcagc tttaccgact gcttcgcccg
    16681 ggcgaacaag tcctgattgg tcaagagaaa gtcctgcaac tttttcatta ttggtcaaag
    16741 caacaataat gtcagttttc ttgccagctt gttctatttc tggcaaatcc atttcagcaa
    16801 tcagggtctc tggtgtgaca aggtatcctt ctttcacgaa tacattgaaa ggaacaccct
    16861 ttagttcaac agtatctaat cccatgtgaa caagtacttc cagcccctca ttagaaagaa
    16921 taccaatggc atgttttgtt tcaaagacac tcgtcacttt accgtttact ggtgcataga
    16981 ctttgccgtt tgacggttcg acagcataac cgtcacccat cattttttgt gagaaaactg
    17041 ggtcatttac ttcagttatt tccttgatgg tccctgcagc gactgcgaat aatgtttctt
    17101 ttgttgcaac tgccgtacca gttgctgaaa caggttcgaa agactgtggc gttgctgttg
    17161 cgccatttgc tgtttgaagt tgtacatcag cagcattttc aggaacagca ggatcaatct
    17221 tattcaaaat tccctgacgt ctaaagatga tcgtcaagcc aaatggaatg atgacagcaa
    17281 tgatcattgc gatgatgaaa ggtacccatg tttctgcttg gatagctagt attcctggca
    17341 aaccgcctac tccgatcgcg ttagctcgaa cacccatcaa gttagcaaac atgccagcta
    17401 atccagagcc gaccattgca gcgacgaaag gatagacgta tttcaaattg attccgaaca
    17461 tagcaggttc agttacgcct aagtaacaag aaatcattgc tggaatcgag atttgttctt
    17521 cttttttatt cccacgatgt aagaagatga tggctaagac tgcagagcct tgggcgatat
    17581 ttgataaagc aatcatcggc cataaattcg ttgatccgaa atctgcaatc agctgcatat
    17641 cgatggcatt ggtcatatgg tggagaccag taatcactaa aggagcatac aggaatccga
    17701 atacggcact aaacaaccag ctgatagaag acgtcaatcc agtatttacg atatttgaga
    17761 tccagcttcc gactgtccag ccgataggac ctaaaataac gtgtgcagct aaaacagttg
    17821 gtaacaatga aaacaatgga acaaaaatca tcgagatcga ctgagggata tatttgcgga
    17881 agaagatttc tagatacgct aacataaacc ctgccagcat ggctggaata acttgcgctt
    17941 gataaccaat catctggact tgagcaaaac caaaatccca aaatggaata tctgctgcgg
    18001 ctgtggaagc tacactataa gcatttaata attgcggaga aactaacgta attcctaaaa
    18061 cgattcctaa tatttgtgta gtacccatct tttttgcaat actccaagtg atacctactg
    18121 gaagaaaatg gaaaattgct tcaccgggta accacaaaaa ggcattgaca ccattccaaa
    18181 acttcgagtg ttcaacgatt gttccaccaa gactttcaaa ctggatacct tcaagtacat
    18241 ttctgaatcc aaggatcaat ccaccgacaa tgattgcagg aatcagtggt gtaaagattt
    18301 ctgctaaaac ggcaatagca cgttgaacgg gatgaaggtt ttgttttgca gctgcttttc
    18361 cttgttcttt ggaaacccct tcaactccag atactgcaac gaagtcgtta taaaaagtag
    18421 aaacatcgtt tcctatgatg acttggaact gtcctgcatt cgtgaacatc ccttttacgc
    18481 taggtatatc ttcgatcgct ttttcgtccg cttttcctgg atcattcagg acaaaacgca
    18541 tacgagtcgc acaatgacta actgcagcaa tattttcttt tccgccgata tcatgtaaca
    18601 gcttctcggc atctgcttga tattttgcca tatcaataaa cccctttctc ttaacttgtc
    18661 tatgcaagtt gtttcttcat ttactatact ttttttcgga gagaattgca agcgttttat
    18721 taaaaagtac gagagaaaat gatatcgttt taaaaagctt aaaataagct tttcttaaaa
    18781 ataggaacat tgaaatacaa aaagagctgt agtatagtga agaaatgatg gaagaacgag
    18841 tgagggaaaa aacatgaata agttcaatga aattttttta gatttggaac agaaaatttt
    18901 agcgaaagaa tatcctccgc attcgctttt acccagtgag aaccaattga tcaaaattta
    18961 tggtgtttca cgagaaacaa ttagaaaagc gctgaatctt ttgactacgg aaggttatat
    19021 tcaaaaaaaa caaggaaaag gttcgatcgt actggatcgg aatcgcttcg actttcctat
    19081 ttctggattg actagctata aagagctaca ggagacccaa cgtattccaa gtgaaacgat
    19141 catccatacg ttagaagaaa cagaagtgac aaaagcattg aacgagatca ctggctggga
    19201 gatcggtgcg cctgtttggc atttgatacg cgaaagaaaa atcaatggcg aagtagttat
    19261 attagacacc gattatctat taaaggaaat cgttcctatt ttaactccag cacaagcaca
    19321 aggatcgatc tatgaatatt ttgaaaatga gctttctttg acgattgctt acgcgcaaaa
    19381 ggagatcaca gtagaagaag taacggaaat catgaaaaca gcgatggatc ttcacgatga
    19441 cacttatgca gtagtagtca gaagcctcgt tcatctggaa gatacccgct gtttcgagta
    19501 ttctgagtcg gttcaccgat tagataaatt ccgtttcgtt gagtttgccc gacgccgaaa
    19561 agtgtaaata gttcaaaaga aagcaaattg ttggcatctg tccactttgg cgctatgata
    19621 ggatcacaaa gggggcattt ttaatggata aaccaataag accagaaaaa gaagaactga
    19681 aagaaaagtt atcacccatg gcttatgcag tcacacaaga aaatgcaaca gaacgaccat
    19741 ttagcgggaa atatgatgat ttttacgaaa aggggatcta tgtagatatc gtcagcggtg
    19801 aaccgttatt cagctctgca gaaaaatatg atgcaggttg tggctggcca tcattcagca
    19861 aaccaataac gaaaagacaa gtgcgcgaaa aagccgattt ttctcatggc atgcatcgaa
    19921 tagaagttcg aagcaaagaa gcagattctc atctcggaca tgtgtttacc gatggaccag
    19981 tagatcaagg tggtctacgt tactgcatca attctgcctc actgaaattc attccatatg
    20041 aaaagatgga tgaattaggt tatggggaat tcaaatcact tgtagaataa tggaaataca
    20101 caaagagcgg tacaatacgg ggatttactc gatcgtccgc tcttttttta ttcaagcgat
    20161 tgctatttga aagaaacgct ccctagactc cttttttcac aaggtgaaat gtgctacaat
    20221 aaagggaacg tatgtgtgca aaagaaagag gactagaata tgtatgaata tctgacaggt
    20281 gtggttacct ttatcaaccc ctattacata gtagtagaaa ccaatggtat cggctaccag
    20341 atcgcactag gaaatcctta ccgctacagt agcaaactaa atcaaaaaat aaaaatttat
    20401 gtccatcagg taatacgtga agatgcgcat cttctgtatg gatttgattc gctagaagaa
    20461 aagcaactgt ttttgcgatt agtaagtgtt tcaggaatcg gtccgaaaag tgcccttgca
    20521 atcatggcaa gcgaagacca ctccggtttg attcaagcag tagaatccag tgatgtcact
    20581 tatttgacga aatttccagg agtagggaaa aagacagcac aacaaatgat cttggatcta
    20641 aaaggaaaat tcggtgagct gagtatcgat acacctttta gtctatttga tgaagcaaac
    20701 acaaaagacg ctacagctct atctgaagca atggaagctc tctcggctct tggttacagt
    20761 gatcgagaaa tcaaacgtgt agaaaaacaa ttaaaagaag tagataatca gacaacggat
    20821 gagtatctac gccaagcact caagctaatg atgaaaaaat aaggaggaga ccaaatgaca
    20881 gatgaatact tgttatcacc agaatctggc gaaaatgaac tgagtttgga aaaatctctt
    20941 cgaccacagc tgctttctca atatatcgga cagagaaaag tcaaacaaga acttcagatt
    21001 tacatcgaag ctgccagaaa tcgggaagaa cctttagatc atgttctgtt gtacgggcct
    21061 cctggattag gaaaaacgac gatggccatg gtcattgcta atgagatgac cgtaaatatt
    21121 cgtacgacga gtggccctgc tatcgaacgt ccgggtgact tagtagcaat cttgaatgaa
    21181 ctggaagcag gggatgtcct gtttatcgat gagatccatc gattacctag agtggtagaa
    21241 gagatgcttt attcagctat ggaagatttc tatgtagata tcatggtagg acaagggcca
    21301 accgcacatc cggttcattt ccctcttcct ccctttactt tgattggcgc gacgacacgg
    21361 gcaggtatgc tttctgcacc tttacgagat cgatttggca tcatttctca tatggaatat
    21421 tatgacgaac aggatctgca ggagatcgtt ttacgttctt cggatatttt tcaaacagag
    21481 atcattgaag aaggggcatt ggaaattgct cgccgatcac gaggaacgcc tagaatcgct
    21541 aatcgcttgc tcaaacgggt tcgtgatttt gcgcaagtcc aaggagacgg gaaaatcgat
    21601 cgtcctatag cggatcaggc acttactttg ctacaggtcg atcaggctgg attggattat
    21661 gttgaccaga aattgttgcg aacaatgatc gagttatatg gcggcggacc agtagggtta
    21721 agtacgcttt cagtaaacat aggagaagag cgtgagacgg tagaagatat gtatgaaccg
    21781 tatctgatcc aaaaaggatt tttaaagcgt acacctagag ggcgaattgc tactgcttat
    21841 gcctatgaac attttggtta cgactatcat atatgatttt tgcttttaga ttggaggaaa
    21901 atgaatgagt gatacaacac gtacgaaaca attgatcaaa aacgtattga ttgatttgtg
    21961 ccaaacgcaa tcttttcgaa aaatcagcgt ccaaaaaatc gcaaacgaag caaaaatcaa
    22021 tcgacaaaca ttttattatc attttacaga taaatacgat ttgcttcgtt gggtctattg
    22081 tgaggatgca ttgcattatt tagatccaca atgtctttca cttgataatt gggaagagca
    22141 agcattgaaa atgctgaaag caattgctga gaagaaagaa ttttatgcaa atactgtgct
    22201 ttctgaccca gaaattttac aaaaagagtt ttctcaactg atccaaaaat catttatcaa
    22261 gatttttgaa caaatggatg aagaaagaca actttctgca agagacaaac tattttatgc
    22321 tcgttttttt tcttacggtt gcagtggtgt attagtcaat tggatcacga atgaatatga
    22381 agaaacaccg atggaaatcg ctatgcagct tttccgttta gccaaggata cggaattata
    22441 ttcttatcgt ctttatgcaa aagaagagtt ggaagaacag taatagaaaa attttttgtt
    22501 ggaaaagcaa taatcgctaa aaggagatgg ggaaatgaca aaaattttat ttgtttgttt
    22561 gggaaatatt tgccgttcac cgatggcaga aggcttgctg agaaaacgaa tagcattaga
    22621 aggaagggaa gcagaatttt ttgtggattc tgctgctaca agcacgtatg aagttggaaa
    22681 gacaccgcac cctggaacga aaaaaatatt aaaccaagaa aaagtagata tgacgaatat
    22741 ggttgctcgg caaatcacac cccacgattt tgaaactttt gattggatca ttggcatgga
    22801 tcaagaaaat gtagaagaac tgaaacgaag agcaccacgc tcagcgcagg ggaaaatcca
    22861 tttgttttta agtagcattc ctggaaaaga aaaagaaaat gttcccgacc catactatac
    22921 caataacttt gatgagacat atcacttgat cacagaaggc ctgaatcatt ggtggaatat
    22981 ttggattgat gaaaataaaa taacaaacaa tttgtaaagt taacgctttc tttttaaggc
    23041 gatgttagag catttccttg tttttttgta aaatgttagg taaaataaaa ttaattaagt
    23101 aacactttct tagctaaagg aggagtgcat tcgatgaacg aagagacagt atcgccaatg
    23161 aagaagctta cgaagttagt tactcatact tcgtatcaac tttttgattc ttttgtaaat
    23221 gacactgaag aacatgctaa gaatgtacga ttgcaaggaa agtttattct tgagctgcaa
    23281 aaagctgcta ctgaacatag tctagttatc ttacaagtaa gagcaaatcg tttgagtagc
    23341 aagtatgaaa cgatctcagg ctgggtggcg acaaaaacgg tcgaaaaaga ccgagtgatg
    23401 atccgcctac aaaacgaaga gcagcagatc cggatggttc ctgtagaaca aattgaaaaa
    23461 ataacaatcc tttcaccagc aggggaacag gaacggttat caaaataatt tataccagat
    23521 agaaaagcac gtatgagctt gtaccatcaa tcattactaa tcaaaaataa ccgaatgctt
    23581 taagctgata tcagtaaaac ggaacgtttt aggatgagta tcatagcatg acagcattcg
    23641 gttgattagt tgaatcgatt ggatggtaca agtttttttg ataaaaaaag gtcctgctag
    23701 ccggggagct agcaggataa ggagttaaaa atgaaaaagt gttgttaggg ttgtttgttg
    23761 gtatgcttat ataatagtca ttagttgtga atattttgtg acgaaagttt tcgaaagttg
    23821 ttaagtt
//
LOCUS       DAFENC010000040        23156 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.042, whole genome shotgun sequence.
ACCESSION   DAFENC010000040
VERSION     DAFENC010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23156
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.042"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(21..221)
                     /locus_tag="LP493_002064"
     CDS             complement(21..221)
                     /locus_tag="LP493_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBL2134209.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(674..994)
                     /locus_tag="LP493_002065"
     CDS             complement(674..994)
                     /locus_tag="LP493_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134210.1"
                     /translation="MKKRLLWCLLSLSLSLTSQPVFAEETQRFPITGTRLYKNVYVQT
                     PDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(1497..2615)
                     /locus_tag="LP493_002066"
     CDS             complement(1497..2615)
                     /locus_tag="LP493_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134211.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            3086..4393
                     /locus_tag="LP493_002067"
     CDS             3086..4393
                     /locus_tag="LP493_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBL2134212.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSVT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETARLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAE
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            4514..5713
                     /locus_tag="LP493_002068"
     CDS             4514..5713
                     /locus_tag="LP493_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBL2134213.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYSSTWTFAVI
                     LTYFVVLEIFYSTFYFLIPLVFFSIFAFSYFSEKRRLLNGLLFNIFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVFLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCIPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYWAQSRATLNPPILLMSGGQGADEKVPE
                     AMAMKQYAMEQGIPERDILVETNSTTTLENMRYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(5740..7008)
                     /locus_tag="LP493_002069"
     CDS             complement(5740..7008)
                     /locus_tag="LP493_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HBL2134214.1"
                     /translation="MEKQLPSPVRILMYMLKWLVVTAILGVFMGSLSAFFLNSLTFVT
                     DIRLAHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNIAHLFRLDKAEREILVISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHAYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAVLA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAAYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRIKEKNKV"
     gene            complement(7178..7819)
                     /locus_tag="LP493_002070"
     CDS             complement(7178..7819)
                     /locus_tag="LP493_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HBL2134215.1"
                     /translation="MEQTMKPYQYFFIKREVEQLLNAYSSVNDSKTVQTVQALAAEKI
                     RDVLGYEPSEIDTFLTTVLDVKLTKTQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQAHTYIGWNDPGTQKKFMVYYEDGKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKK"
     gene            complement(8228..8731)
                     /locus_tag="LP493_002071"
     CDS             complement(8228..8731)
                     /locus_tag="LP493_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBL2134216.1"
                     /translation="MTEKWREDEEYMSYVEDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(8854..9618)
                     /locus_tag="LP493_002072"
     CDS             complement(8854..9618)
                     /locus_tag="LP493_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HBL2134217.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKEEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAANKEISTFLVSDEVMDAVSDLPTPQGILAVMALTAE
                     GTPDFSGGWLLLDNVQDPGNVGTMIRTADAFDMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLTEVIPLMKDKGFTVYGTELNEEAHALDKVEKSDNFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            9726..10001
                     /locus_tag="LP493_002073"
     CDS             9726..10001
                     /locus_tag="LP493_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HBL2134218.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            10561..11511
                     /gene="yidC"
                     /locus_tag="LP493_002074"
     CDS             10561..11511
                     /gene="yidC"
                     /locus_tag="LP493_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBL2134219.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVVIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPANNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(11557..11958)
                     /locus_tag="LP493_002075"
     CDS             complement(11557..11958)
                     /locus_tag="LP493_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBL2134220.1"
                     /translation="MSRQLVLISHGKFCEELKKSTEMIMGPQEDIYTLPLLPEDGTET
                     YKQKFLTVTDSLNDFVVLCDLLGGTPANIISKLIMEGQQITLYAGMNLPMVIEFINSQ
                     MIGSEPEFVRAGCESIVSVNELINGIAEEEE"
     gene            complement(11972..12781)
                     /locus_tag="LP493_002076"
     CDS             complement(11972..12781)
                     /locus_tag="LP493_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL2134221.1"
                     /translation="MTKSNYKLTKEDFKQINRRSLFTFQLGWNYERMQGSGYLYTILP
                     QLRKIYGDNTPELKEMMKTHTQFFNTSNFFNTIITGIDLAMEEKEGIASKETVSGLKA
                     GLMGSFAAIGDSVFAALIPTIFGALAANMATDGNPIGVFIWIFAQIVVMVFRWKQLEF
                     AYKEGISLVTTMQSRLTALTDAATLLGVFMVGALVATMINVKFSWAPTIGDVTLNMQN
                     YIDMILPKILPAGIVGGVYWLLGKKNMTPTRAIFIVLIVCVALSALGVISK"
     gene            complement(12768..13658)
                     /locus_tag="LP493_002077"
     CDS             complement(12768..13658)
                     /locus_tag="LP493_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2134222.1"
                     /translation="MDIQWWQILLLTLYAGYQILDELQIYSSMSAPVFAGLYAGLVMG
                     DLNAGLIIGGSMQLTVLGVGTFGGASKIDANSGTILATAFSISLGMNPEQAIAAIAVP
                     VASLMIQLDILARFANTYFAHRIDRHVEDMNYQAIERNFLMGALPWSLSRMIPVFLAL
                     AFGGGLVENVVSVLNGNLKWLGDGLSVAGAVLPAVGFAILLRYLPVKKHLSYLILGFT
                     ITALLATLFSNVQLLGTSVASVVKDLPATFNSLPMLAVALIGLALAMISYKNDQNKDH
                     QPLASEPSHSVEGEIEDDEI"
     gene            complement(13671..14150)
                     /locus_tag="LP493_002078"
                     /pseudo
     CDS             complement(13671..14150)
                     /locus_tag="LP493_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632653.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
     gene            complement(14326..15267)
                     /locus_tag="LP493_002079"
     CDS             complement(14326..15267)
                     /locus_tag="LP493_002079"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexose kinase"
                     /protein_id="HBL2134223.1"
                     /translation="MITTVTLNPSIDIAYTIEELNLDKVNRVETVNKTAGGKGVNVAR
                     VLNLLGEEVIATGLIGGQHGEYLKNQLDQLGIMHQFVPIKGETRDSIAILHSSRQTEL
                     LERGPFITKKEQQTFTDHFEQLLEISDIMTISGSLPQGCPLDYYKQLVALADKKGKDI
                     LLDTSGKFLLEVLEGKEKPLLIKPNLEELGELIGQRICSSIQLEKIQSLLAHPIFEGV
                     PWVVVSLGERGAVAKVAQCFYEVIIPKISVVNPVGSGDATLAGSAHALSKRQSIEEIL
                     AFSMACGMANAQQEKTGWIDPMKVTMLMKHIQVKKIK"
     gene            complement(15264..16259)
                     /gene="lacD"
                     /locus_tag="LP493_002080"
     CDS             complement(15264..16259)
                     /gene="lacD"
                     /locus_tag="LP493_002080"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBL2134224.1"
                     /translation="MNEEKNRAMERLSTKDGIISALAIDQRGALKKMIKSLGKEPSED
                     QISEFKELVSAELTPYASAILLDPEYGLPAAKVRAKETGLLLAYEKTGYDATTPGRLP
                     DLLADWSSLRLKEQQADAVKFLLYYDVDEAPEINHLKHVFIERLGSECEGENRPFYLE
                     LVSYDAQISDSSSPEYAKVKPHKVIEMMKEFSDPKYKVDVLKVEVPVNMNYVNGYSTG
                     EFIHSKEEAAAFFKEQSEATPLPFIFLSGGVSTELFQQTLIFAHESGSTFNGVLCGRA
                     TWKDGVKAYVENGKDGAIHWLRTNGRENIETLNKVINETATPWFNKTKSKKVKMK"
     gene            complement(16252..17448)
                     /locus_tag="LP493_002081"
     CDS             complement(16252..17448)
                     /locus_tag="LP493_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL2134225.1"
                     /translation="MFELSKNKLKQIGAAITTQEIKQQPDLWKETIDRLMQSQENLAL
                     FFDQIKKEANGRRIRVIFTGAGTSQYIGDTLLPYLNEHGDNQFFIFHSFGTTDIVASP
                     KEFLFPNEPTLLVSFARSGNSPESVAAVQIANEQVETLFHLTITCAKEGMLAKNAQDD
                     KQNYLLLMPERANDAGFAMTGSFTCMLLSALWIFDQTAMEKKERYLEQLVKIGQDLLS
                     RDQEIQKLLPDFFERIAYLGSGSLAGATREAQLKILELTAGKVATIFDSSMGFRHGPK
                     SFLNSETLVVGFVSNQPYTRNYDLDILEEIKEDRVTANVIAIAQPGTIDFSGMTVLLE
                     DSVSKLPDAYLALAMIMTAQIIALYTSIKVANKPDTPSPTGTVNRVVKGVIIHKYETE
                     GEMTDE"
     gene            complement(17466..18194)
                     /locus_tag="LP493_002082"
     CDS             complement(17466..18194)
                     /locus_tag="LP493_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2134226.1"
                     /translation="MESSNKGKSLYYQLVDLLKDRIETQMTPHDKLLSERELCQHYGV
                     SRTTVRLALQELENQGYIYRRHGKGTYVSDLSDKSSNLAGAYSFTEEMREIGRVPKTV
                     ILEFRQMEANKRIAKNLNIHLGETVFKLKRLRLADEEPLMVERSYLPAKLFMGLDLPL
                     LESKPLYDVFSQDYEQQVQLADEEFYASIVQKKDAVVLRIADGAPVLHLTRITYNVKN
                     EIIEYTDSVARADQFHYKIRHIRK"
     gene            complement(18635..19609)
                     /gene="lacD"
                     /locus_tag="LP493_002083"
     CDS             complement(18635..19609)
                     /gene="lacD"
                     /locus_tag="LP493_002083"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBL2134227.1"
                     /translation="MKKMSIEKQERLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPEYGLPAAALREKECGLLLAYEKTGYDAKMPGR
                     LPDLLNSWSVKRLKEVGADACKFLLYYDVDEPVEINVQKQIVIERIGSECEAEGIPFF
                     LELLSYDATIGDPSSLDYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVEGYG
                     QDTCYSQAEASAYFYEQSKVTEQPFIFLSAGVSAALFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLEETATSIYVNK"
     gene            complement(19606..20064)
                     /locus_tag="LP493_002084"
     CDS             complement(19606..20064)
                     /locus_tag="LP493_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL2134228.1"
                     /translation="MTIIHEENIFLQQPLDNQEEAFKFLAKQTFCLGIAHDEKEVYQK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSLIIVTLKKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRAAKSKIEIATILTKEIGEDI"
     gene            complement(20061..21524)
                     /locus_tag="LP493_002085"
     CDS             complement(20061..21524)
                     /locus_tag="LP493_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL2134229.1"
                     /translation="MGKYQLIAATGCPTGIAHTYMAQEALEQAARKKGITIKVETHGQ
                     IGIENELTAEEIKQADAVIIAADKDVHSERFVGKRVIDVSVSTGIKDAQRLIDEALAG
                     KGTVLADNEAADTLEPEAISGANFGRSIYKNLMNGVSHMLPFVVAGGVLIAISFAVWG
                     IYSSDPDHAQYNATAAMVKAVDDAAMGMMVPVLAAYIAEGIAKRPGLVVGFVGGIVAM
                     NGGTGFLGGILAGFLAGYFILFLQKLLIILPKQLDGLKAIVLYPVIGVAFIGIVMSLL
                     AGPMKAINEGMMSFLAGFEYSNPLVLGVIVGCMCAFDMGGPVNKAAYVTGTALLTQGN
                     TTFMAGASAACIAPPLITGFATLLFGKYFDTNDRNAGLVNFILGSTHITEGAIPFAAK
                     DPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVTGKIQWVTAILIGSIVGG
                     VILGLIQKKRVTDKDKKRDNKATNRTVIEEGRAGGLS"
     gene            complement(21506..22438)
                     /gene="pfkB"
                     /locus_tag="LP493_002086"
     CDS             complement(21506..22438)
                     /gene="pfkB"
                     /locus_tag="LP493_002086"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBL2134230.1"
                     /translation="MSIYTCTMNLAIDLFIETDEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQQKQIQTEFIEVPGMTRINVFTQVNQTGEE
                     YKLVNQGPEIPQTAVHNFLNQIRALQAGDYLCVSGSLPRGLSPKVLIEISRICLIIDS
                     SDQEVMDCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVESGAENVLLSLGE
                     KGAILFTKDRVIRGNSPKGKVVNTACAGDAMLGTFLAGYMNRRSLDETLRKSIAAGSS
                     TAFRKGLTDFLDVEELSKQIKIKEERFERWENIN"
     gene            22580..>23156
                     /locus_tag="LP493_002087"
     CDS             22580..>23156
                     /locus_tag="LP493_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL2134231.1"
                     /translation="MNHKLSETEQYLWNFIEHLILEIPNYSIVKLSEQANVSTATIVR
                     TMKKKGYEGFTSFKHHLKEGENKNINFSFLDKVDKGIRRAILKNEQEVVRTINMLEIG
                     NIEDAIQRIKFADRVFVFARGFSEMIGQEMLVKLQLTGKNCQMHTDPEIIKSISRKLT
                     KKDSVIFVSLNGEKTNKNIKNKIYVFIFQFFK"
BASE COUNT         6954 a         4957 c         3889 g         7356 t
ORIGIN      
        1 tattttttag tataggttaa ttaagcttta gtaacgtttg ttgcttgagg tccgcgttgg
       61 ccttcttcaa catcgaaagt tactgcttgg ccttcttcta aagttttgaa tccgtcgcct
      121 tggatagctg agaaatgaac gaatacatcg tttccgtttt ctgcagtgat gaatccaaat
      181 cctttttctg agttaaacca ttttactgta cctgtttcca taataaaaat cctccttgtg
      241 tatcaacaca tattttgcaa ttacttgaat ggtgtatatc tggaagatgt ttatttgaaa
      301 caagctacca cagattaccg aacaaaaact actcctatag tatatcatac cgtttacaaa
      361 aaagctagag tttttcgact ttttttatta aaaaaagttt tctcagcgat tacataaagt
      421 gaaaaaccga actttttttt aaaataaacg acatattgtt cagttggtgt ttttttgctc
      481 tgatgttctt ttttaaacta aaaaaattat tctttctgac tacttatcgg ttctgtttca
      541 acggtcgagg ctggggaaga ttctttagta ggtctgatgt tctcatggta tttctgatag
      601 cctatgacag ttaccagaag aacaaggcaa accaatacga ccaacgagat tagtttttct
      661 tttttgctca tatctatacc tcataaataa caggatgatg tccatcatat ttctgagtat
      721 gagtaaaagc aaaagctgca gctgtagaat gtaagaaatg ccagcaactt tcataatcac
      781 aggtcggaca gtaccaaaag taaccaaatc ttggctgcaa agaccgttct tctgtttcag
      841 gaatcgcaga atcaagatct ggtgtctgta cataaacatt tttgtacaga cgtgtgcctg
      901 taataggaaa ccgctgtgtt tcttcagcaa aaactggctg acttgttaaa cttagggata
      961 gagacagcaa acaccataac agtctttttt tcataaagac ctccttatcg ataagttttt
     1021 cccaattaaa atcatatctc aagaacgccc gttattcaca ttttgttcat aaatgatgtt
     1081 ttttgtatca taatcgtcaa aaagaggtcg tgaccacgtc acaacctctt ttttaaacgg
     1141 tgttccagaa gtagcttctt cggaaataag ccgaaatttc acaaaaattt gagaaataat
     1201 ttttgtcaat ctcttcttat ttcttgaagc tgaccacttc tgtcacaacc tcttccttaa
     1261 acggtgttca aaagcttgca tctgcggtaa taagcccacc aaacaaaaaa tatgaagagc
     1321 tatttttgct tgctgttctt attacttgat gcagaacagc tttttcacaa cctctcatac
     1381 acggtgttta atcagctgac cttcggtatt agctcaaaaa acggcaaaat atgtgaaact
     1441 atttttccgt ttgtttctct aatactcagg tcaaaacact gatttcacaa cctcttttaa
     1501 taacgaagaa tcgctgtcag actcttttca tctggcgcat ctttttgatc caaaataaac
     1561 acttttccgc cattaatgat cacatcatct gctaatgcat tcaacacttg acgccgatca
     1621 tattctgttt caggatcttc accgaaacca tcagctaagt ttgacgtagc gataaataaa
     1681 tgtgacactt ttccttcttt cgcagctgga acgatatcaa ctaactgatc gatgaatttc
     1741 ttatctaaga gtttattgta ttcttttgat tcttgagctg cgagttcact tgacagcttc
     1801 ttcgcccctt cttcgatatc tctaaaggat agctgcgcag gagaagcaga aatcgcaacg
     1861 tctgcacaat aatagggatt tttagcaatt tttttgaaca tcgtctgatt ttctggtaga
     1921 gcaaataaat aaatcggcca ttgttctgga ttttcgaaag aatccttcaa gtacgtatca
     1981 actgcttggt aatagttgac ccaatcgatc tctacttctt catcttttgg atttacgcca
     2041 tggaaagtta ctccatctcg ggctccgcct cctccattag aagagaagtt caaaccgcca
     2101 cctgtcagtt cagatcccaa tgcagtaacg acatcaaccg gtgccccttc tggtagagat
     2161 acttctttta cttgtttgtt gctgacttca tacaatttca tggagtcgcg gttcaatccc
     2221 aataaataat aagaatagtt gaactgccca tttttgataa tagccagtaa ataaggaaga
     2281 tcacttacat agtattgatc gtctaccggg atactcaaac gatggatata ggtttggtca
     2341 gcagttataa tgaccgctac actcgtagtt gcactacgcc aaaacgaagg atctcctaac
     2401 aaattttcaa ttttttcttg gaacggggac cagtcatgtt cggaatattt tttctcaaaa
     2461 cgtttctttg cttctttcgc aaaatttttg aatttgatct gatctttttc cacatcttga
     2521 tgggcgacat gcgtattcag catgatcgtg acgaatggtc ctttagcgcc ttctgaagtc
     2581 aattgtgaca ataattcttt atcctttttt gccataaacg tacccctcct aaaaaaatca
     2641 ttcctttgtt tctatctaaa gtctaccaca acactatttt tccatacaat aaaacgtatc
     2701 taaaaaaata aaacggtttc tacggtttta aatttagcta tttttttaag ttatcttcat
     2761 aatttcctca attatttagc cccagtcttc aactattctt catgaaatgc tgataaacta
     2821 agaaaaagaa taaaagaggt ggatcttatg catttgatta tgattttcag tttattaagt
     2881 attatcagtt tatttgcttt cagcgcttcc cgcttattag atgcggaaac acagcctatt
     2941 cctgtaaaag tacgtaaaaa cgaccgctaa ccttccataa cgtgcgttct tatcctaaag
     3001 ttttttcaga aacattgaaa ctctctcccc tctctgataa aattttaatt tgtagcgaaa
     3061 caaattaatt acaaggagat cggatatgtc cataaaaaaa acacgtctag tcctattatt
     3121 ggctagtctc attctttgcc ttgcttcttt tctaccagct gttgctgtgc aagctgaaga
     3181 tactttcaaa gtaaatgcaa aagcagcctt tgctgtagat gcgcaaagcg gtaagattct
     3241 ttatgatcaa gatggagaaa aaaccatggg gatcgcttca atcacaaaaa tcatcggtct
     3301 ttacatcgtc cttgatcaag taaaagaagg gaaactatca tgggatgata aagtttcaat
     3361 ttcagattat gcagaaaatt tgagtgtcac cccagattta tcaaatgttc ctttgcataa
     3421 agaaaacacc tacaccgtta aagaattatt cgactctgca atcatccagt cagccaacgc
     3481 ttcaatggtt gccttggcag aaaaaatctc tggcagcgaa gcaaaattca ctgaacgaat
     3541 gaaagaacaa ttgaaagatt ggggtatcaa agatgcaacg atcgttaatg catcaggact
     3601 gaataactct tatcttggcg aaaaccgacc agaaggtact ggagaaaacg acgaaaatca
     3661 aatgtctgct caagatgtgg ctatcgttgc ccgtcatttg atcttggatt ttccagaaat
     3721 actggatgta tctagcacta cgacacaaat gtttggcgaa aacacgcaat caccagtaga
     3781 aatggtcaac tggaactgga tgctcccagg attcgtgaat tataaagaag gcgtggacgg
     3841 attaaaaact ggtacgactg aacttgcagg agcctgtttc gtcggtacga tcactaaaaa
     3901 cgatcaacga atcatcactg tcgtattgaa tgcagacggc catgcggaaa acccaagtgc
     3961 ccgtttcaat gaaacagctc gcttaatgga ttattgctac gacaattggt cagaaaaaga
     4021 gcttggaaaa gccaatgcaa gtatccctag tctaaaaacc attgatgtaa aagacggaaa
     4081 agaatcaaca gtgcccgttg tgcttaaaag tcctgtaaaa gtatgggtac ggaacgatat
     4141 ggatactgga aaattaacaa tcacaccaac tcttgacaaa aaacaagtca ctgacaatga
     4201 gatccaagca cctatggata aaggaacaaa aatcggtacc gcaacgatca ccttggcaga
     4261 agataaatta ggttatcttg aagacaacaa cgcgccatcc acagaaatca tcacggataa
     4321 aaccgtagaa aaagcaaata ttttcgttat tggctggcga cgcgtcgcag aatttttcgg
     4381 taacttgttt taattgaaca aaaagaaaaa agcatctttc catgtggaag atgttttttt
     4441 gctttttcta gtttaaataa cagctttttt catctatttt cgttatactg tataagaaaa
     4501 aggagttgaa tttatgaatc taaccagaga tctgattttt ttggttctct atcttattgg
     4561 ggtattctcc atcgtttatt ggcgaaaaca gaaaaaggat ccttccttgt tcttttacag
     4621 cagtacatgg acgtttgcgg taatcttgac ttattttgtc gtgttggaaa ttttttattc
     4681 gaccttttat tttttgattc ccttagtgtt tttcagtatc tttgcctttt cctatttttc
     4741 agaaaagcga aggctgttga atggtctttt attcaatatt ttcctcatta gttttggtat
     4801 ctacttgttt gtcttgctat acgaaacaca aaatattttt cttggcggac tgattgcctt
     4861 gatcacgatc ccgttactgc ttgtctttct attcggcatt tatggattga tcgtttttct
     4921 tttttggaac ggtgtcacag ttttacgtag agagtcgcat tcattagcta atcttttaac
     4981 gttgatacta gccatttttc ttacattgtt tcttgttttt gactttttct tgttaaaata
     5041 tttaccacaa tggataaatg ctttgttttt ctgcatccca ttgatcttga tctatctatt
     5101 tatcgtattc tacaactttt tgactgtctc attcttgtat cagttcaacc gccctcgata
     5161 caaccaagac ttcatcgttg tgttaggcgc cgggttgatc aatggagaaa cagtttctcc
     5221 tcttcttgcc aagcgaatca ataaggcgat tgctttttat tgggcacaaa gccgtgcgac
     5281 attaaatccg cctatcctat taatgtcggg tggacaggga gcagacgaaa aagtaccaga
     5341 agcaatggcg atgaaacaat atgccatgga acaaggaatt cctgaaagag atattcttgt
     5401 cgaaaccaat tcgacaacca ctttggagaa tatgcgctat tcaaaggaaa tcatggatca
     5461 gcaaatgaaa ggtccctatc gcgcgatctt cagttccaac aattaccaca ttttcagagc
     5521 tggtctctat gcacgacaag cgaaactgaa ggcaaatggc attggggcaa aaacagcttt
     5581 ctattacttg cctaacgcgt ttttaagaga atacatcgcc atcttgatga tgaacaaaaa
     5641 aagacatatg atcatttgcg gattgctttt cgcaggttcc gcattcttat cactgatcac
     5701 tttacttttc taaaaaaaca aggtgtgaca aaacatatgt cacaccttgt ttttttcttt
     5761 tattctcttg acgattggca agaatagtat tccttttttg acggctactt gctgtgcaga
     5821 ataaataccg ctgtttcctg aacacataaa gctgatcaag cagatcataa agaagtaagc
     5881 agcagcttgt gaaccaaata attcgattcc catcacaaaa caggcaatcg gtgtatttgt
     5941 cgcaccagaa aataccccga taaaacctaa tccagcaaga aaaggaacag aaacatggag
     6001 caaaggcgct agtactgcgc caagcgttgc accaatctca aatagtggtg tcacttctcc
     6061 cccttggtac cccgcaccta aagacaagac cgtgaagaat aatttcccaa taaaatcata
     6121 agcatgtgcc tgtccattaa atgattcctg cagtaacgga agactcaacc caaggtaacg
     6181 ttgtgtttgc aaaatcaacg ctgcggctac aactactgct ccacctatcg tatttcgcca
     6241 aacaggatga ggaatccatt gcgcataccg cgcttttaaa aagacgatcg aacggctgaa
     6301 tacccaacca atcaaaccaa aagcaatccc agcaacaaaa actttgaaga acagcaacat
     6361 actccattca ggaatcacac ccatttggta atgtagatga gaaacaccat agctttctgt
     6421 catgaaattt gcaaaaagcg cagcaaagaa gctaggaaat attgcttctg ttcggacttt
     6481 accgattgcc aacacttcta atccaaataa tgttccagct aaaggtgtgc caaatacaga
     6541 actaaaaccc gcactgattc cactgataac caaaatctcc cgttctgctt tatccaatcg
     6601 gaataaatgc gctatattat cagctaatgc tccccccatt tgaactgctg ttccttcacg
     6661 accaacagat cccccaaata aatgggtagt gatggtccca aacaaggtca atggaatgag
     6721 ccgcaaaggg atcttctctt ctcctccatt cccttgatcg atcactaagt tattcccacg
     6781 actagaaaga ccgccatgat acgcataaag ataagcaaaa agcgcgccgc tgactggcaa
     6841 tagataaagt agccaaggat gtgctagtcg gatatctgtc acgaacgtca ggctatttaa
     6901 gaaaaaagca gacaagctcc ccatgaatac tccgagaatc gctgtgacca ccagccactt
     6961 caacatgtac atcaaaatac gcactggact cggtaattgt ttttccataa aaaattcctc
     7021 ctcaaataaa aaaacgccta ctaaagaaag gggctggccc cagactttag taggcgtcat
     7081 tagctatctt acgttagcat ttaaaggcga acaccatcac ctattcactt ccattaaaag
     7141 atagcatatt tttctgtaaa aaacaataaa attatcgtta tttctttaca cgttcagcaa
     7201 attcatagaa aggagccaat ttcgttaact gttgattaca ttgatcacta tcatgacaaa
     7261 tataattccc ctttttcgta tacgtgccat cagaaccggc tttcgttgta gaaagaaaga
     7321 gcgagacatt cgatgttttc tgacagatcg cacagattcc cttattaatc gttggtgata
     7381 aagtaccgct gatccctttt aattttccat cttcgtaata aaccatgaat tttttttgcg
     7441 tccctggatc attccaaccg atgtacgtat gtgcttgcaa gtcgatttca ttccaagcgg
     7501 gttgtttgag ttttttcact tttcggaata atttctcgat ttgtggtttg ctcggctgca
     7561 taaacggctg gacgatttgc ttcagctcct ccaatgctcg ttctgcttgc gtttttgtca
     7621 gttttacatc taaaactgtc gttaaaaacg tatcgatttc tgatggttcg taacctaata
     7681 catcgcgaat cttttcagct gctagagcct gaaccgtttg taccgttttt gagtcattga
     7741 cagatgagta cgcatttaat aactgctcta cttctctttt tataaaaaaa tattgatatg
     7801 gtttcattgt ttgttccatg attttaaagt cctttcttct aaccaaagtg catactttgt
     7861 agaaaaaagt gatcttctgc aaagtatgtg ttacctgaag atcccggact cttttaaata
     7921 agatacgttt tgcatcttat catcaccccc tttaatgttc attcttctat gtacatgatt
     7981 cattcgataa ataaaagtaa accgtatctt gagcagatag tcaactgcaa acagaaaaag
     8041 gactgtgaca aaagtcgtgt caaagtccct ttctacaaac aaacggtgtt ccagaagtag
     8101 cttcttcaaa aaataagccg gaatttcaca aaaatttgag aagcaatttt cgtaaattcc
     8161 ttcttatttc ttgaagctga cccacttctg tcacaacctc aatatggtct attattggtt
     8221 ttacctgtta aatcgaggat tcttttccga agtaacgttg ccatctctta cgcatacttg
     8281 ctgacatagg ctgagcggct tctttgactg cgcagtattt gtctacgaat gttacgatat
     8341 atccttcttt gtacttaggc ggtgcaatcg ttgcgcccca catgtgcttc aaaatgatat
     8401 ctcgctcaag atccgacaaa tcggtgatct tttctgcatt ctttacagcg attcttggat
     8461 ggatatacgc atgtgtgcct tcatcaaatt tcgtcgtacg ccaatcatag tagaacagat
     8521 catgcaaaag tccagcacgc gctgttgctt tagcattgcc accccatttt tttgcgagca
     8581 gataactata gtaagaaaca ctgatggaat gctccaaacg agtggaatga acatgctgtg
     8641 tgtaattcgc taattttttc actgcttctg tttctaaaag atcttctaca taagacatat
     8701 attcttcgtc ttcacgccat ttttctgtca taattatcga tctgccacct ttttgaattt
     8761 cattttcttc tgaaattgat ctaagtatac caccagtgtt cggattattc tagtcgcctt
     8821 ggataaaata gccaaagctt aatagttcct taatcataaa gaaaaatgat aaagaacaat
     8881 ccctgccgca accccaacat tcaacgattc cgcatttcct ttcatcggga tatatacgtt
     8941 ctgatcagtc aaagacaaga tttcctgact taccccctga ccttcgttcc ccatgattat
     9001 tgcgaagtta tctgattttt ctactttgtc taaggcgtgt gcttcttcat ttaattctgt
     9061 gccatacact gtaaaccctt tgtctttcat taaaggaatc acttctgtca aatctttttg
     9121 caacacaggc aaatgataat tgcttccctg catgctgcgc agcacctttg tactataaat
     9181 atctgccgtt cctttgccta ataaaacacc agccatatca aatgcatctg ccgtacggat
     9241 catcgtccct acatttccag gatcttgtac attatctaat aacagccatc ctcctgaaaa
     9301 atctggcgtg ccttcagccg ttaacgccat cactgctaag attccttgtg gtgtaggtag
     9361 atccgataca gcatccatga cctcatccga aactagaaaa gtagaaatct ctttgtttgc
     9421 ggccagccag tctccccatt ctttcatgcc tcgctgtgtc acaaaaagtt cttttatttc
     9481 tgcatcagac gacgcagctt cttcaatcag atggaaccct tccaaaagat attcttcctt
     9541 ttcttcccga tatttctttt tatgtagttt ttttaattct ttgattcttg gattttttgc
     9601 tgattggatc tctttcacat tcctcacctc cccatgatta tatcatggaa taggtgcttg
     9661 agcttgtttc atcctaaaaa aatcggtatc attaatttat aaaataggaa agaaaggtga
     9721 cgaacatgcg caaagttaaa atgaacgtcc aaggacgcgt ccaaggcgta ggatttcgct
     9781 acatgaccaa gatggtcgct gatcaactag gcgtgactgg aacggtaaaa aacgaagatg
     9841 acggctcagt cacgatcgaa gcaatcggca atgacgacat catccagaaa tttattgaag
     9901 aagtcaagaa atctccgagc ccaagtggac gagtgcagta tgtggatgtc caagaagacc
     9961 cgatgattga ggaacgaaag aaatttgatg tggtgggata aggttgtgaa aaagctggtc
    10021 tgcatcaagc attaaggaca ggttgtgaaa aatagctctc catatttttc aacaggctgg
    10081 acttaatgcc gtagatgcaa gcttttgaac accgtcaata aggttgtgag aaagtcgctt
    10141 agttttgagt agtaaggaga attttgtgaa aatggctttc cacatttttg cataaaattt
    10201 gacttaatac cgagaaactg acttttgaac accgtcgata aggttgtttt tgagacgctt
    10261 tgcctcaagt attaaagata ggtagtaaaa aagctgatct ataacttgca ataaatttgc
    10321 ttaacccata ttttccagac agaacaaaaa agtttttagt tttttaaata agaaagaaac
    10381 acttggaatc actcttttct ttccaagtat ttctttcttg attttttgtc tttttttcaa
    10441 aatttttcgc tacgtaaaag aacgaatatt tatatgaaat ttctatgaag ttgattgaat
    10501 tccatgcgct tttttagtat agttaagttt gtgtaaaaat tatagaagag gaagtattct
    10561 atgaataaat ggaaaaactg gttattggga tccggacttg tcagtatcct gctcttttta
    10621 tctggctgtg tgcggatgga ttcaaacgga aaccctgaca cttcgggaat cgtttatcga
    10681 gtactcgtcc atcctatggg ccaagcgatt acatatctag ttgagaattt caattggtct
    10741 tatggctggg cagttattgc aatgactgtg atcgtccgta tcatcatctt gccactaggt
    10801 attagtcaat cgaaaaaaac aatgatccaa tctgaaaaaa tgcaagcgtt aaaaccacaa
    10861 gttgaagcag cccaacaaaa attgaaagct gcaacaacac gtgaagaaca aatggcagca
    10921 caagcagaaa tgcagcaagt ataccgcgaa aacggattga gtatgaccgg cggaatcggc
    10981 tgtctgcctc tattgatcca aatgccgatc ttctctgcct tgtactttac ggcacgttat
    11041 acagaaggta ttcgggaatc atctttctac ggcatcgatt taggctcacc aagtatggta
    11101 cttgttgtca ttgcaggggt cgcctatctg cttcaaggat acatctcaac gatcggtatt
    11161 cctgaagaac agaaaaagac gatgcgtacg atgctaatcg tctctcctgc tatgatcgtc
    11221 ttcatgtcga tcagtgcgcc agccggtgtt acactttact gggtagtcgg tggtgtgttc
    11281 agctgtctgc aaacattcat cacaaacgtt atgatgaaac cacgtttgaa agcacaagtg
    11341 gcagaagagt tgaaacaaaa cccgccaaaa caagtcgtca ctccaagaaa agacgtgaca
    11401 gaatcagcaa agccagctaa caacaaacaa gcaacaaaac aaatcaaaca accaaaaaac
    11461 agtacaaaca acaaaggccg caacgcagga aagcagcaga agcggaaata aaaacatagg
    11521 acaaaaaaga tgagagctaa gccctcatct tttttgttac tcttcctctt ctgctattcc
    11581 attaattaat tcgttgacag agacaatgct ttcacatcct gcacgaacaa actcgggctc
    11641 tgaaccaatc atttgtgagt tgataaattc aatgaccatc ggaagattca tcccagcata
    11701 aagagtaatc tgttgtcctt ccattattag tttagaaatg atatttgcag gtgtaccacc
    11761 taaaagatcg catagtacca caaaatcatt taacgaatct gtgacagtga gaaacttttg
    11821 tttgtatgtt tcagtgccat cttctggtaa taaaggtaac gtgtagatat cctcttgagg
    11881 ccccatgatc atttctgtac tttttttcaa ttcctcacaa aattttccgt gactaatcaa
    11941 taccaattgt ctactcattt ttcgctctcc cttatttcga aatcacaccc aatgcagata
    12001 aagcaacaca cacaattaat acgataaaaa tcgctcgagt aggagtcatg tttttctttc
    12061 ctaataacca ataaacacca ccgacgatcc cagcaggtaa aattttaggt aagatcatat
    12121 cgatatagtt ttgcatattc aatgtcacat cgccaatcgt tggtgcccat gaaaatttaa
    12181 cattgatcat tgtcgcaact aatgccccta ccatgaatac ccctaataaa gtggctgcgt
    12241 ccgttaatgc agttaagcga gattgcatag tagtaactaa ggaaattcct tctttgtatg
    12301 caaattcaag ttgcttccaa cgaaaaacca tgacaacgat ctgagcaaaa atccatataa
    12361 acacacctat cggatttcca tcagttgcca tattcgccgc caaagcccca aaaatcgttg
    12421 gaatcaaagc agcaaatacg gaatctccaa tcgctgcaaa ggaacccatc aatccagctt
    12481 tcagccccga tacggtttcc tttgaagcaa ttccctcttt ttcttccatt gcaagatcaa
    12541 tcccagtaat gattgtatta aaaaaattag aagtattaaa aaattgcgta tgtgttttca
    12601 tcatctcttt taattctggt gtattgtctc catatatttt tcttagttgt ggcaagatag
    12661 tatataaata gccagaaccc tgcattctct catagttcca acctaattga aaagtgaaca
    12721 aacttcttcg attgatttgc ttaaaatctt cttttgttaa tttgtaatta gatttcgtca
    12781 tcttcgattt ccccctcaac agaatgtgat ggctcactag ctaatggttg atggtctttg
    12841 ttttgatcat tcttataact gatcattgct agtgctagac caatcaatgc tacagcaagc
    12901 atcggcagcg aattgaaagt tgccggaaga tctttaacaa cgcttgccac acttgttcct
    12961 aataattgaa cattagagaa taacgttgct aataatgccg tgatcgtaaa tcctaaaata
    13021 agataagata gatgtttttt tactggtaaa tagcgcagaa gaatggcaaa cccaacagct
    13081 ggtaaaacag ctcctgctac tgaaagtcca tcgcctagcc attttagatt cccgtttaaa
    13141 acagaaacaa cattttcaac taatccacca ccaaatgcta aagctaaaaa tacaggaatc
    13201 atacgagaga gcgaccaagg taaagctccc attaagaaat tgcgttcgat tgcttgataa
    13261 ttcatgtctt ctacgtgacg gtcaatacga tgggcaaagt atgtgttagc gaatctagct
    13321 aaaatatcca attggatcat taagcttgct acaggcactg caatagcagc aatcgcttgt
    13381 tctggattca ttccaagaga aatcgagaag gcagttgcta aaatcgtccc agagttggca
    13441 tctatttttg atgcgcctcc aaacgtcccc actcctaaaa ctgtcaactg catactgcca
    13501 ccaataatca aacctgcgtt taaatcaccc attactaaac ctgcatataa ccctgcaaac
    13561 actggcgcac tcattgaaga atagatctgt aattcatcta aaatttgata acctgcatat
    13621 aatgttaata ataagatctg ccaccattga atatccatgg atcattcctc ctatttgatt
    13681 aaaagattca taaagtcttc tgctttatcg tttggtacca tttgagcaat taaatgtata
    13741 ccaagctgat ctaatttttt aaatacttcg atatctgcat ctaccacatt gattgatttt
    13801 gtaatggacc gtgtttcatt cgtttgtgac atattcccca catttacttc tttgatagga
    13861 actccttttt ctactaaaga taagattcga tctggctttt ttgctacgat caatactcgt
    13921 tgagagtcat atttgccagc taaaatattt gttgctgctt tttcgattgg caaaatgctt
    13981 aattttaccc ctgctggagt cgctaacttc aatccacttt tttcaattgt gtttgtggct
    14041 acctcatcat ccacgaccat gattcgacta atattcagtt tcgttgtcca aagatttgct
    14101 acttatccat gtatcaaacg tccatcgatt cttacaccaa taattgccat catgcattct
    14161 ccttatctat tttttctatt tattgttcaa ttaaaactgt gacatcatca aatatccctt
    14221 ctgtttcaaa gataacgttt tcattttttc tttcttatat ttcattttta agctaagaac
    14281 aaattccttc ccaactaaag aaaacgcttt cttttatatt taagttcatt tgattttctt
    14341 aacttgaatg tgtttcatca acatcgtaac tttcataggg tcgatccagc cagttttctc
    14401 ttgttgcgcg tttgccatac cacaagccat agaaaatgcg agaatctctt cgattgattg
    14461 cctttttgat aacgcatggg ccgatcctgc aagggtcgcg tcacctgaac caacaggatt
    14521 aacaactgat attttaggaa taatgacttc gtaaaaacac tgagcaactt ttgccacagc
    14581 acctctctct cctaaagaaa caacaaccca tggcactcct tcaaatattg gatgagctaa
    14641 taaggactga attttttcta attgaatcga agaacagata cgttggccaa tcagttctcc
    14701 taattcttcc agattgggct tgataagtag tggcttctcc ttaccttcca atacttcaag
    14761 caaaaattta ccagaagtat ctagtaatat gtctttccct tttttatcag ctaaagcaac
    14821 caattgctta tagtaatcaa gagggcatcc ttggggtaaa ctacctgaga tcgtcataat
    14881 atctgatatt tcgaggagct gctcgaaatg atcggtaaat gtctgttgtt ctttctttgt
    14941 tatgaagggg cctcgttcca aaagctctgt ttgtctcgaa ctatgcagga tagcaataga
    15001 atcccttgtc tctcctttaa ttggaacaaa ctgatgcatg atccctaact gatctagctg
    15061 gttctttaga tattcaccgt gctggccacc tattaaacca gtagctatca cctcttctcc
    15121 taataaattt agaaccctcg ccacattcac tccttttcct cccgctgttt tattgactgt
    15181 ttcaactcga ttgactttgt cgaggtttaa ttcttcaatt gtatacgcga tatcgatgga
    15241 aggattcaag gtaactgtcg taatcatttc atcttcacct ttttgctttt tgttttattg
    15301 aaccaagggg tagcggtttc atttattact ttatttaaag tctcgatgtt ttctctccca
    15361 tttgttctta accaatgaat agctccgtct tttccatttt cgacgtatgc tttgacccca
    15421 tctttccatg tcgcacgtcc acacaataca ccattgaagg tggaacccga ttcatgagca
    15481 aaaatcagtg tttgttgaaa taattctgtt gaaacacccc cactcaaaaa aatgaatggt
    15541 aatggagtcg cttcactttg ctccttaaag aaggcagcag cctcttcttt gctgtgaata
    15601 aattcacctg tggaatagcc attcacataa ttcatattga ctggtacttc tactttcaac
    15661 acatcaactt tatattttgg atcagaaaat tctttcatca tctcaataac tttgtggggc
    15721 ttgactttcg catactctgg agaagaacta tcgcttattt gtgcgtcata agaaactaac
    15781 tccaaataga agggacgatt ttctccttcg cactcactac ctaaacgttc gatgaacaca
    15841 tgcttcaaat gattgatttc gggtgcttca tcaacatcgt agtaaagtaa gaattttact
    15901 gcatccgctt gctgttcttt caatctgaga gaagaccaat ccgctaataa atcaggtaga
    15961 cgaccaggcg tagttgcgtc atagccggtt ttctcataag ctaacaataa ccccgtctct
    16021 tttgctctga cttttgctgc tggcaatcca tattccggat ccaataaaat agcagaagca
    16081 tagggtgtca gctcagctga tactagttct ttgaattcac tgatttggtc ttcacttggc
    16141 tcttttccca acgatttgat catttttttt agagcaccac gctgatcgat cgctaatgca
    16201 ctaataatcc catcttttgt tgatagtctc tccattgccc tatttttttc ttcattcatc
    16261 tgtcatttct ccttcggttt catacttatg aataatgacg cccttgacta ctcgattgac
    16321 cgtgcctgtt ggagatggtg tatctggttt attagctact ttgattgaag tatagagtgc
    16381 aatgatttgt gcagtcataa tcatcgctaa tgcaagatag gcatcgggca atttactcac
    16441 cgagtcttcc aatagcacag tcatacctga gaaatcaata gtacccggtt gcgcaatcgc
    16501 aatgacattg gcagtgaccc gatcttcttt tatttcctct aaaatatcta agtcataatt
    16561 tcgcgtatat ggttgattgc tcacaaaacc tacaacgagt gtctcgctat ttaaaaaaga
    16621 ctttggtcca tgacgaaacc ccatcgaaga atcaaaaatt gtagcaactt tacctgctgt
    16681 taattctaaa atttttaatt gtgcttctct tgtcgcacct gccaaacttc ctgaacccag
    16741 ataagcgatc cgttcaaaaa aatcaggtaa taacttttga atttcttgat ctcttgaaag
    16801 aagatcttga ccgattttaa ctaattgttc aagatatctt tcttttttct ccattgctgt
    16861 ttgatcaaag atccataaag cactcaataa catacacgta aaacttcctg tcatagcaaa
    16921 acctgcatcg tttgctctct ctggcatcaa taacagataa ttctgtttat catcctgtgc
    16981 gttttttgcc aacatcccct ctttagcaca agtaatcgtc aaatgaaaca atgtttcaac
    17041 ttgttcattt gcaatttgca cagccgctac actttctgga ctgttgccac tgcgagcaaa
    17101 tgaaactaat aaagtcggtt catttggaaa caaaaattct tttggtgaag ctacaatatc
    17161 tgtcgtgcca aaactgtgga agataaaaaa ctgattgtct ccatgttcat ttagataggg
    17221 taagagcgta tccccaatat attgagacgt tcctgcaccc gtaaaaataa cacgtattct
    17281 tcttccgttt gcttcttttt ttatttgatc aaaaaataga gctaaatttt cttggctttg
    17341 catcaatcta tcgattgttt ctttccagag atctggttgt tgttttattt cttgtgtcgt
    17401 gattgctgca cctatttgtt ttaatttgtt cttcgatagc tcaaacatgt tgttctccct
    17461 ctcaatcatt ttcggatatg ccgaatttta taatgaaact ggtccgctct tgctacacta
    17521 tctgtatatt cgataatctc atttttcacg ttataggtta tcctcgtcag atgtaagacg
    17581 ggagcgccat cagcgattcg tagcacaaca gcatcttttt tttgcacgat acttgcataa
    17641 aactcttcat cagctaattg aacttgttgt tcataatcct gtgaaaacac atcatacaac
    17701 ggtttacttt caagtaacgg caaatcaagt cccataaata gtttcgccgg tagataagaa
    17761 cgctcaacca tcaatggctc ttcatctgcc aaacgcaatc ttttaagttt aaatacagtt
    17821 tcacctaaat ggatgttcaa attcttagca attctcttat tagcttccat ttgtctaaat
    17881 tctaaaatga ccgtcttagg gacgcgccct atttcgcgca tttcttctgt aaagctatat
    17941 gctccagcta agttcgatga cttatcagac aaatcagaga cataggtacc ttttccatgt
    18001 cttcggtaaa tataaccttg attttccaat tcctgtaaag ccagacgtac ggtggtacga
    18061 ctcaccccat agtgttgaca aagttctctt tcagataaca gcttatcatg cggagtcatc
    18121 tgtgtttcga tacgatcctt caataaatca actagttgat aatacaatga ttttccttta
    18181 tttgagctct ccataaaaat cacctcttct ttactggtta taaccacaac acaagaatag
    18241 tgaattatta atcatttgtc aaaggttttt tagaccaaaa aagctattat aacagctctt
    18301 taaagcttta tatcttgaat agacaaagat acctcaaaaa taccagttac caataaaaga
    18361 acagaaaaaa agacgaacca cataagcgat ccgtcaaaat ggtctaactt atcgagcagc
    18421 gtgatccaca ttaatcccta tgatattcct acaactatcg ttttattact tccaatatca
    18481 tttacaacaa ctaaaaatag cttattaatg acaaatgtta ttattagttt tagataactt
    18541 ttgcagtttt atactttttt tctataaaat ttgacaaaca tttttttaaa taactaatta
    18601 ttttttgaat ctgtcactca gacaatcctt tctcttactt gttaacataa atagaagttg
    18661 ctgtttcttc taatagtgta cttaattctt taatattttg ttttccttct tctaacatcc
    18721 aactactcgc tttttcttcg ccttcggtaa caaaaggtgc tactcccttc gcccatgttg
    18781 ctcgcccaca taagacacca ttgaatgtcg aacctgattg ttttgcaaaa cgcaatgtat
    18841 cttgaaatag tgcagcgctg actcccgcac ttaaaaaaat aaacggttgt tcagtcactt
    18901 tcgattgttc atagaaatac gcggatgcct ctgcttgact ataacaagta tcttgcccat
    18961 atccttccac aaatctcata ttcactggta cttctacttt caatacatcc acttgataac
    19021 gttcttttga aaattctcgc atggcttcaa tcactttatg cggttttact tttgcatagt
    19081 caagagaaga cggatcgcca atagttgcat cgtaagaaag gagctctaaa aagaaaggta
    19141 tgccttctgc ttcgcattct gaaccaatcc gttctataac tatttgtttt tgcacattaa
    19201 tctctactgg ttcatcaacg tcatagtaca ataaaaattt acaagcatcc gcacccactt
    19261 cttttaacct tttcactgac caactattca gtaaatctgg tagtcggcct ggcattttcg
    19321 catcatagcc ggttttttca taagctagca acaaaccaca ttctttctct cgaagcgctg
    19381 ctgcaggcag accatattct ggatcgagta aaatagcgga agcatacgga gtcaggtact
    19441 gagaaaccat ctgtttaaat tggatgatat cttctgatgt agcttcttta tattggttga
    19501 tcattttctt caaagcacca cgttggtcga tagctagcgc gctaataatt ccagcttcat
    19561 ccgtcaatcg cttcaaacgt tcctgttttt ctatactcat tttcttcata tatcttcacc
    19621 tatttcttta gttaatattg tagctatttc tatttttgat tttgcagctc tcaactgttc
    19681 tgtaacctct tttcgcatca atgatcgtgc aacgagagac aataatttca aatgagtcgt
    19741 tcctgcttct gaatctggga taaataacgc aaaaataaaa tcaactgact gtctatctaa
    19801 actgttccat tcaattcctt ttttcagtgt gacgataatc aaactaggtt cattgattgt
    19861 ttgagacttc gcatgaggga tagcaaaacc tgacattatt cctgtagtac cttctttttc
    19921 tctttccaga agtttttgat atacttcttt ttcgtcatga gcgattccta aacagaatgt
    19981 ttgctttgct aaaaacttaa atgcttcttc ttgattatct aatggctgtt gtaaaaaaat
    20041 gttctcttca tgaatgattg tcatgataaa cctcctgctc ttccttcttc gataactgta
    20101 cgatttgttg ctttattatc cctcttcttg tctttatcag ttactctttt cttttggatc
    20161 aaacctagta tcactccacc aacgatcgaa ccaataagaa tcgctgtaac ccattggatt
    20221 tttcccgtca ctacaggtaa cactaaaaaa ccgccatgtg gggctggtac ttggacacca
    20281 aacagatagg tcaagacagc agcaattgat gagcctaaca tcatcgttgg taatactcgg
    20341 atcgggtctt tcgcagcaaa cggaatagct ccttccgtaa tatgagttga tcctaaaata
    20401 aaattaacca aacctgcatt acgatcatta gtatcaaaat atttaccaaa caataaagta
    20461 gcaaaaccag taatcaacgg tggtgcaatg caagctgctg acgcaccagc cataaaagtc
    20521 gtgtttcctt gtgtcaaaag agctgttcct gttacatatg ccgccttatt aaccggtcct
    20581 cccatatcaa acgcacacat acagccaaca atcacgccaa gaacaagtgg attcgaatat
    20641 tcaaatccag ctaaaaagct catcattcct tcatttatag ccttcattgg acctgccagc
    20701 aaagacatca cgatgccaat aaatgctaca ccaataactg gatataagac gattgccttc
    20761 aagccatcta gttgtttagg taaaattatc agtagctttt gcaaaaataa gataaaataa
    20821 cctgctaaga acccagctaa aatacctcct aaaaatccag taccgccatt catggctacg
    20881 attccaccaa caaatccaac gactaaccct ggacgtttcg cgatcccttc tgcaatataa
    20941 gctgctaaaa ctggaaccat cattcccatt gctgcatcgt caactgcttt taccattgcc
    21001 gctgtagcat tgtattgtgc atgatctgga tcagaagaat agattcccca aacggcaaat
    21061 gaaatagcaa tcaatactcc gccagctacc acgaaaggca acatatgaga gacaccgttc
    21121 atcaaatttt tatagatgct acgaccaaaa ttagcaccac ttatcgcttc tggttctaaa
    21181 gtatcagcag cttcattatc tgctaagaca gtaccttttc ctgccaatgc ttcgtcaatc
    21241 agccgttgtg catccttgat tcctgtactg acagaaacat caatgactcg ttttcccaca
    21301 aatctttctg aatggacatc tttgtctgcg gcaataatga cagcatctgc ctgtttgatt
    21361 tcttcagccg ttaattcatt ctcgatccca atttgtccat gggtctccac tttgatcgtg
    21421 atgccttttt tcctagctgc ttgctctaat gcctcttgcg ccatgtaggt gtgcgcaatt
    21481 cctgtcggac aaccggttgc tgcaattagt tgatattttc ccatctttcg aacctctctt
    21541 ccttgatttt gatttgttta cttaattcct ccacatccaa aaaatcagtc agtcctttac
    21601 gaaaagcagt agagctgcct gctgctatgc ttttacgtaa cgtttcatca agcgatcgtc
    21661 gattcatgta tcctgctaaa aaagtgccta acatggcatc acctgcacat gctgtattga
    21721 caacttttcc ttttggcgag tttcctcgaa tcaccctgtc tttcgtaaaa agaatcgctc
    21781 ctttctcacc gagggataac aaaacatttt ctgcgcctga ctctactagt cgttgtccat
    21841 aaacaaagta atcttcatct gtaaccattt ttcgtccgaa ccaagaagaa agttcttcct
    21901 catttggttt cagcaaaaac ggtcgatagg gtaaacaatc catgacttct tgatcactac
    21961 tatcaataat caaacaaatc cgactgattt ctattaaaac ctttggagac agccctcttg
    22021 gtaaactccc agaaacacaa agataatccc ctgcttgtaa tgctcttatt tgatttaaaa
    22081 aattatgaac agctgtctgc ggtatttcag gtccttgatt cactaatttg tattcttctc
    22141 ccgtttgatt gacttgtgta aatacattga tacgcgtcat accaggcact tcaataaact
    22201 ctgtttggat ttgtttctgc tgtaaatagt cttctatata ctttcctgtg aacccagcag
    22261 aaaaacctaa tgccgtactt gggaaatcta gcatctttaa tactagtgac acattcaccc
    22321 cttttccgtt tgcctgaatg tcatcctctt ttgtgcggtt taccataaaa ggatgcatct
    22381 catctgtttc aataaataga tcaattgcca aattcatcgt gcatgtgtag atagacataa
    22441 ccaacgacct ccttgattct attatgaaat acgcgaaata gaaaatgttt tcttaatcgt
    22501 cccaacacaa agaaaacctt tacatttata aactcgtcgt gcttttttta actaactttt
    22561 ggtgaaagaa ggaaagaata tgaatcacaa attaagtgaa acagagcagt acctctggaa
    22621 ctttatcgaa cacctcatcc tagagatccc taactattcc atcgtgaaac taagtgaaca
    22681 agcaaatgtc tcaacagcca ccattgtgcg gacaatgaaa aagaaaggct atgaagggtt
    22741 tacttcgttt aagcatcatc taaaagaagg agaaaacaag aacatcaatt tttcattttt
    22801 agataaagta gacaaaggaa tccgccgagc cattctaaaa aatgaacaag aagtggtacg
    22861 tacaatcaat atgttggaaa tcgggaacat tgaagatgca atacaaagaa tcaaatttgc
    22921 tgaccgggtt tttgtctttg cccgaggatt ttcagaaatg attggccaag aaatgctggt
    22981 aaaacttcaa ttaacgggaa aaaattgtca gatgcatact gatccagaaa ttatcaaaag
    23041 catcagtcgg aaactaacta agaaagacag cgttattttt gtttctttga acggtgagaa
    23101 aacaaataaa aacatcaaaa ataagattta tgtctttatt tttcaatttt ttaaat
//
LOCUS       DAFENC010000041        22494 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.043, whole genome shotgun sequence.
ACCESSION   DAFENC010000041
VERSION     DAFENC010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.043"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            150..278
                     /locus_tag="LP493_002088"
                     /pseudo
     CDS             150..278
                     /locus_tag="LP493_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
     gene            392..631
                     /locus_tag="LP493_002089"
     CDS             392..631
                     /locus_tag="LP493_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134232.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKDVFKSLSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            743..937
                     /locus_tag="LP493_002090"
     CDS             743..937
                     /locus_tag="LP493_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134233.1"
                     /translation="MEEKLLKTMKQKHLKRLSVMQYINDMQITGKEKACLLGSMKNFE
                     QLRRTYVKTSSNCQLLLEVS"
     gene            1023..1694
                     /locus_tag="LP493_002091"
     CDS             1023..1694
                     /locus_tag="LP493_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HBL2134234.1"
                     /translation="MRKWLFGFLGVALIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQQEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            1747..3723
                     /locus_tag="LP493_002092"
     CDS             1747..3723
                     /locus_tag="LP493_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBL2134235.1"
                     /translation="MAINRYVKKAGMLIGMLGIIAGCFQGYRAYAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PREDSDLTNAKVDEIVQDVEDKGSNSEYVKNATNKITSAVDENGEITFTDQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDKTGSGFLKNIHLYPKNIVSKLSFELTK
                     FGDDGADQSKQTLLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GQGLSYVAAKANIKVTNKDGSVVLKENTDYKIQNSENGFVIDFIVNNGQVSDTVASLH
                     GQDLQMTYNMYVNDSAAVANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLVDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGEYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQTYVLISCLLLGAGALSAVVYFKKKA"
     gene            3738..4490
                     /locus_tag="LP493_002093"
     CDS             3738..4490
                     /locus_tag="LP493_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL2134236.1"
                     /translation="MIIRKPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIAAIDRTGTAAETDSSLDVAKIELGDPVGILTILSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLESNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEEN
                     KKQKLSWKWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            4506..5261
                     /locus_tag="LP493_002094"
     CDS             4506..5261
                     /locus_tag="LP493_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134237.1"
                     /translation="MRNRKWLFVCAAALFSFTAYTQLTFADRQESTDSTEQTIQTSDS
                     STIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGHEKQEGVNG
                     AKFSVYDVSDILQKMDVKDLTTDQIESQLKNRVKKLSSDQLKLVSNEETKTIDQQTGV
                     FEFSVEVQANQKQAYYIVNESSPENISNSEDILLLTPVSDKNGEFLKDVWIYPKSEAS
                     QPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            5274..5534
                     /locus_tag="LP493_002095"
     CDS             5274..5534
                     /locus_tag="LP493_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134238.1"
                     /translation="MKLIKLLLFNFSCLTAVFLYCGLLFSKLSILPSYQLYLMRILNI
                     PAASMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            5531..7621
                     /locus_tag="LP493_002096"
     CDS             5531..7621
                     /locus_tag="LP493_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBL2134239.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKSTDLKGEYAHYDKMNTTDWYVRKDTVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVNDKMLQVGDTIQYRIKQKVNRLGVDLLAV
                     YDRFELIDNLPKEVNYVDAHVESGTNKKFDVSGEVTYDKTKHQVKYAAKADTLKNRMK
                     YNGETYELVINVKVNELANQNSVAKNQGTSIINKVEKDTNIITVYFPKIPVKEVQQNG
                     KDVNGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDPIEARLT
                     YKEGSAQVIDKSKGKDITSEGTLTYDSNSRTLKWEASADFLSNNLLDGREIQLIFTAK
                     TPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTISAVSLLL
                     LVLATFSYAVLRYI"
     gene            7648..8112
                     /locus_tag="LP493_002097"
     CDS             7648..8112
                     /locus_tag="LP493_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134240.1"
                     /translation="MKKLIIVVTSLIAMIVILVGCSNEKNKQTNQDNGVLKSGTMWKE
                     EVGGLVYNLKIIDETTWEYSESVWHPDPVQITVKRQKDYKGLERYKIVDSAGVREFIN
                     KSDSLFIVVPYEKNGVKKIIFLGSSKDEKRTKEKLIHDGSQSNKYKLQKTSE"
     gene            8109..8351
                     /locus_tag="LP493_002098"
     CDS             8109..8351
                     /locus_tag="LP493_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HBL2134241.1"
                     /translation="MIASLFICPEGGITVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            8369..8671
                     /locus_tag="LP493_002099"
     CDS             8369..8671
                     /locus_tag="LP493_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134242.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAAAA
                     VASIVIGGLFFLFGRRGAENGKMHVGYVLMGVGVILAAASIVVSLFGLFGQTPQGL"
     gene            8741..10804
                     /locus_tag="LP493_002100"
     CDS             8741..10804
                     /locus_tag="LP493_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134243.1"
                     /translation="MYFTIAGNTKTDKELIKKATKEVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGKVLEHESRSSVKLTLTLHDTEGKIEKAGTEYVFGPLDYQISEGFYPTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVNQGSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETAEVEVDPVEA
                     NEESTWTEGDSQEYIEPLISEEVEKNEIEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKAKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCVA
                     KINNFTQTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMEKYEKIQQELQVQIPKWKKEYEIQQQELKEQEEKQRQKEKEREQLELKKREQD
                     LAEQQMAIEKQRLNQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPTPSVAAVQTPM
                     NNQTNLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTTSIKEE
                     AQEQARKEYEQQLEELLNRTNQSTTESSMENSKESDSSKAKEGSSDSTVQSNTSESSE
                     SNEVK"
     gene            10804..13416
                     /locus_tag="LP493_002101"
     CDS             10804..13416
                     /locus_tag="LP493_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBL2134244.1"
                     /translation="MRVRETTKRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     KKIFYSGLVYLPLEYLVTRVPEVFNRLEIVKGSLQGINLFQLQEMPQVFHFDSAGFWN
                     PFTPTTSLGTRLAISTVCVVPAVLMGLKMDMWFRPLADGQKGDNRLMTLKEIQQIYPQ
                     IPETKTTFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     KQSSMVVNDPKTELYVGSKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPDNEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSVGFPKYLDLKLHESLLNQRVVVEFYHKGK
                     KFHEERVKVGYKGFCEINFDCHLVAGDQVCLKYDHQGKEYVAWYEFSQRVLKDEEGNI
                     VYRKKRGETHLPELEKEAVLTLDEEKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNML
                     WDLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENS
                     TINSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNH
                     GETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGL
                     HDQLEEKNEENMFYKIVQSLENETAKKLLIQFYEEQAADRLQEYVEKLIKNKEISEMI
                     GKRLLLESEKVVKE"
     gene            13413..15944
                     /locus_tag="LP493_002102"
     CDS             13413..15944
                     /locus_tag="LP493_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134245.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDANPKTVTKVLQDYGNYLQYQDV
                     FSWIWNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNALFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKSFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PKQAKEMADKDKSGLSDLQKDRLRALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYR
                     RYSSKPGIILAGESSLAVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSA
                     IEDISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQ
                     SVTKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGF
                     GHRKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGT
                     AEDLTEKAKDTLEEKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLKDAYGEGQV
                     NAAVKANTTTEKENQEGIVIPSVKDHQEALHSNENSIEEKNSIEERNSEEGKNGQLPK
                     TDPEQYRYKPNSDLENEKRISDLSKVNQEDKAENEGQLPKTDPEQYRYRSVNSENEKR
                     ISDLPKRNQEVQTDEDSIVLPNDNGIEVGTEKSTKIGLPKAQNLPMKDSRLNQFKEND
                     QSFVHQSTAGTVQMKPSRLPENGNLTTVSYNLSESGETGNASVQNVVTREAAPKPIQN
                     VHTGYKPANVAFTAPTKINVTRETKNRNNALKEQLLRDIKQDIKP"
     gene            15994..16326
                     /locus_tag="LP493_002103"
     CDS             15994..16326
                     /locus_tag="LP493_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134246.1"
                     /translation="MDKYINMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKMVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFADKNHYHALDPNRNY
                     HGTYKEDE"
     gene            16327..16920
                     /locus_tag="LP493_002104"
     CDS             16327..16920
                     /locus_tag="LP493_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134247.1"
                     /translation="MRVKGQNSVERKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLKKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            17083..19107
                     /locus_tag="LP493_002105"
     CDS             17083..19107
                     /locus_tag="LP493_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HBL2134248.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTETQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNAINPDFIETVNYVTNFQ
                     REMRKVEAMTVLATQSPQEMVPENMSSDNFSKLKKVFEFSSTKIFMRMDESILRHIEG
                     LVGKSMTNSELESIPQQNQGDAVINFGSKETIRVHFSPNKRQLKLFDGGK"
     gene            19107..20312
                     /locus_tag="LP493_002106"
     CDS             19107..20312
                     /locus_tag="LP493_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBL2134249.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWVFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYK
                     LLPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKF
                     PNSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMS
                     IITSNKLTEYDEFAIKHWGEGGNNNGTITGEWTNPFPGSSLDKSSFSGGQLFGTNPGG
                     EFRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVY
                     QEFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFTDDGTWIDP
                     LPFLNSSKK"
     gene            20328..20972
                     /locus_tag="LP493_002107"
     CDS             20328..20972
                     /locus_tag="LP493_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134250.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQETNTFKIEEVAK
                     NASEKLKKNSSEAQAKIDKLNQTINEKNQEIEQLKQQDGTKAKEEVTEAQSKTAEEFG
                     KLAIDKSLSRNELTEKLKDVATQEVIDKLSPADDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVTDFSYFTR"
     gene            20983..21789
                     /locus_tag="LP493_002108"
     CDS             20983..21789
                     /locus_tag="LP493_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134251.1"
                     /translation="MSKKKGERQRFKKRKSYLRWLGIFMILGFLILASPIYTHQKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIKAKVIKVSDDYFAVKLSHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQMKDQEEIIQKLQEKIDRMTKEKI"
     gene            21811..22041
                     /locus_tag="LP493_002109"
     CDS             21811..22041
                     /locus_tag="LP493_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134252.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYVAAKKYFTADNK"
BASE COUNT         8317 a         3519 c         4629 g         6029 t
ORIGIN      
        1 atcaaataaa caagaaccgt aggaactacg gggatagctt ggtaaataag aggcacctct
       61 gttagtaaag taatacgcta tcaagtatgc tctcttccca agaagctccc acttcaagcg
      121 taagaaaccg ttaggtttag ctaagtggtg agtagttcac aatgacgctt acgaatgata
      181 atggagacga attatctgtt gaagatactt ggtcatattt gagtgattat attgtcagcg
      241 ttgaaatcat tgaatttgta gcggataaag aagaataaaa actggaggaa taaattttac
      301 agataaaggc ttagaagaag tcacgacgaa taataaaaag gtagtattac cttaggcatt
      361 gagtaaggaa ttcatttagg aggaaaatta gatggcgcga ccagttttag aggcgatgga
      421 tatggatact ttgacaaaag gaaggtatgt acagctgtta gctcgtggtt attcacctaa
      481 agatgtattc aaatccctgt ctaaaggaac agatatggaa aaagaaagat tacgaaaaga
      541 attcgattat tggagaaccc ataatggaat caaggatttg aaaccagcac ggccagtaat
      601 taaacgaaag aaaaagataa cccaagactg aagtgtagag cgtatgtgat cataggcttt
      661 tttatttttg caaaaaacaa ggaaggtagg aaaactcatg aattatgaag aaatcgaaaa
      721 cagaaaaaaa gtgtcgaaat aaatggaaga aaagttgcta aaaacgatga aacaaaaaca
      781 ccttaaaaga ttatctgtca tgcaatatat caatgatatg cagataacag gaaaagagaa
      841 agcttgtttg ttaggttcaa tgaaaaactt tgaacagttg agacgaactt atgtgaaaac
      901 aagttctaat tgtcaactat tgttagaagt ctcatgacat tcattaatag aattcatttt
      961 taaaactttt tctatggaaa tgagaaaaag attttttgtt ttgtctgaaa gggggtagct
     1021 ggatgagaaa atggttattt ggttttttag gagtcgcttt aatcgtcttt tgcagtgtgt
     1081 ttggctatgt tagctaccaa aaacatgaag gagaggtgtt taagcaaaat atagaaaaaa
     1141 agatgcccgt agatcaaatc aatgcacatg caaagagtta taaggaggat gcaacgaacg
     1201 tcaataatga tatgtctttg gggcaaatgt tgtccataca acaagaagca atcgaaatgg
     1261 gcgtcaataa acaagtattt gcacaaattc agattcctgc acttggttta gcattgccaa
     1321 tttttaaagg ggcaaatcaa tacactttga gtcttggagc ggctacttat ttttatgaag
     1381 atgctgaaat gggcaaagga aactatgtcc tagcaggtca taacatggaa atgccaggtg
     1441 ttttattttc tgatattcaa aagttgtcat taggggaggt gatggactta gttagtaacg
     1501 atggcgtcta tcgttacaag gtaacgcgta aatttatcgt acctgagtac tttaaattaa
     1561 tcgatggcgt tcctgaagag aactctttct tgtctttgcc aaagaaagga gagaaaccct
     1621 tattaacgtt gtttacttgt gtttatacgt cacaaggaaa agaaagatac gtggtacagg
     1681 gagaactaca ataacaaggt tttaatcaac gtgagtcgtt gaaatatgaa atgaggagag
     1741 taaaaaatgg caataaatcg gtatgtaaaa aaagctggaa tgcttattgg aatgttagga
     1801 atcattgcag gctgctttca gggatatcga gcatatgcag aagatgtcac gcaaaaaacg
     1861 ccaccagaga aggtcaatat cacggttcat aaattaatgt acgatcaagg aacgcaattg
     1921 aatgttgata ttgacgggat caaaaacgat ggttatacgc acgatcaata tcctacaggt
     1981 gtaacgaaat acaacaaggc agattatggt gatgttgagt ttacgttagg aaatattacg
     2041 gatcaagtat taccgagaga agattctgat ctaaccaacg cgaaagtgga cgagattgta
     2101 caagatgtag aagacaaggg atctaacagt gagtacgtca agaatgcaac caacaaaatt
     2161 acttcagctg tagatgaaaa tggtgagatc acttttactg atcaaccagc ctatgtcaat
     2221 tccaaaggga atgtatatgt ggtttatgaa agtaaatccg ctgctggatt agtcacacaa
     2281 aaagcaaaac caatggttgt gattgcgcca atgacagata aaacaggatc aggattttta
     2341 aaaaatattc atttgtatcc taagaacatt gtttctaagt tgagttttga attaacgaaa
     2401 tttggtgacg atggcgcaga ccaaagcaaa caaacccttt taaaaggggc aaaatttgag
     2461 ttatacaagg gcgaacctgg aaaaggaaca aaattgggtg atcttgtatc ggatgatcaa
     2521 ggaaagctga ctgcgactga tttgacgtta ggaaaatact attttgtgga agttccttcg
     2581 gaagttgtag tgggatcaga tcaagaacca acagcagatc aatatttatt aggcgcagac
     2641 gctcgcaacg atgcgcacaa taaattaacc tttgaaatta cgaatgatgg cgtgacaagt
     2701 gacttaaaag cttcatacgt aaactataaa gcaccagtga tcgataaaac agtaacaaat
     2761 ggaacaggac aagaacattc tttccaaatt ggtgacgcag taaattatca aggaacgatt
     2821 catattccaa cagacattgc aggtggcgca gacggtatca cagtaaacgg tgtgaaaagt
     2881 gaaacttctc cttacagtgt atttaaatgg ggagatacag caggacaggg actttcttat
     2941 gtcgctgcta aagcaaatat caaagtaaca aataaagatg gatctgtggt attaaaagaa
     3001 aatacagatt ataaaatcca aaattcagaa aatggctttg tgatcgattt tatcgtgaat
     3061 aatggccaag taagtgatac tgtagcaagt ttacacggac aagatcttca aatgacttat
     3121 aacatgtatg taaatgacag cgcagctgtt gccaatccat taacaaatag cgtggatttc
     3181 gtttataaca acaatccatt taatcaggaa gaacaccacg aaaaaacgaa agctgacgtt
     3241 gtgacttatg gtgcaaaatt cttaaaagtc gatagcggac tatttggaac aggaatcaaa
     3301 gcaacaccgc ttgaaggcgc agaatttgct gctaaaaacg cagaaggaaa atattatggt
     3361 ggattagttg atacggataa agacggtgtc aaagaagcag tatgggtaga cgatgtagca
     3421 aatgcagcga tcctaaaatc agataaagaa ggtcactttg aaatcactgg tttaactgaa
     3481 ggtgaatatt cactggaaga aacaaaagcg cctgaaaact atcaaaaatt aacgaaagag
     3541 atctctttca aagtagacaa agattcatac aaagaagaaa accgaatcac gatcaaaaac
     3601 aatcaaaaag cttccgtacc aatgaccggt agcaacggtt ttcaaacgta tgtattaatc
     3661 tcttgcttgt tgctaggagc aggggcactt tctgcagttg tttactttaa gaagaaagcc
     3721 tagaaggatc aaaaccaatg attatcagga agcctaagaa aaagcgaatc atgggtaaat
     3781 ggatcattgc tttctggtta ctttcagctg taggtgtctt acttttgatg cctgctgaag
     3841 cgagcgtggc gaaataccaa caaaatcagc agattgccgc aatcgatcga acaggaacgg
     3901 cagcagaaac ggattcttct ttggatgttg ctaagattga gttaggcgat cctgttggta
     3961 ttcttacaat tctaagtatt tctttaaaac taccaattta tgacggaacg tccgacaaaa
     4021 ttttagaaaa tggtgtaggt attacggaag gaactggtga tattacagga ggaaacggta
     4081 aaaatccttt aatcgcaggt catagtggac tttataaaga taatcttttt gatgatttac
     4141 cttcagtaaa aaagggagaa aagttttata tcaaagttga tggtgagcag cacgcttatc
     4201 aaatcgatcg gattgaggaa gtgcaaaaag acgaactaca aagaaacttt gtcacttact
     4261 tagaatcaaa tcccaatgaa gatcgagtaa cgctaatgac atgtacgcct aaggggatca
     4321 acacacaccg ttttctagtg tatgggaagc gagtaacctt tacaaaatca gaattaaaag
     4381 atgaagaaaa taagaaacaa aaattatctt ggaaatggct tttaggaagt actgtttttc
     4441 tttcagtcat gatcattggt tcgctatttg tttataaaaa gaaaaaataa aggagggtaa
     4501 ccaacatgag aaatagaaaa tggctatttg tttgtgcagc cgctcttttt tctttcactg
     4561 cctacacaca gttgacgttt gcagacagac aagaaagcac ggatagcaca gaacaaacaa
     4621 tccaaacgtc agatagcagc acgattcaaa gcagcgatga aaccgtcgat tcgtcaacag
     4681 ttgattcttc agaagaacct aaaattgctg aagacgatca aatagtcaaa cagaccattc
     4741 acgttcaaaa gattatttct tcagaacaat tagacaacca ggggcatgaa aaacaagaag
     4801 gagtaaatgg cgcgaagttt tctgtttatg atgtatcgga cattttacaa aagatggatg
     4861 ttaaggatct cactactgac caaattgaat cccaattaaa aaatcgagtg aaaaaactat
     4921 ccagtgatca attgaagcta gtttctaatg aagaaacaaa gacaattgat caacaaacag
     4981 gtgtctttga attctcggta gaagtacagg caaatcagaa acaagcttat tatattgtca
     5041 atgaatcaag tcctgaaaac atttctaata gcgaggatat tttgctatta acacctgttt
     5101 ctgataaaaa cggtgaattc ttaaaggatg tgtggatcta tcctaaatca gaagcttcgc
     5161 aacctaaaga agaagtaaaa aaaatcgttt ctactggcgt aaagaaaaac ttctttgaga
     5221 attgttggga ttttgttact cacttgtttt ctagagatta aggaagaaat aaaatgaaac
     5281 tgatcaaatt attattattc aatttttctt gtttaaccgc agtctttttg tactgcggtt
     5341 tattattttc taaactatct attttgccaa gctaccaact atacctaatg aggattttaa
     5401 acataccagc tgcttccatg ccgctagata ttatggaaaa gctcattagg aatccattat
     5461 ttactacgat caatttgatc gttattgtcg gaatttcact agtcatttat aaaaaagagg
     5521 ggatgaaggg atgaatttta aacactcgtg gacaagacgg ttaaaatatg tttttcccat
     5581 aatgatgatg ttaggtacat tgtttgggtt aaaaacagcc aatgtctttg ctgaaaaagt
     5641 tattgtcgat ccgtcaaatc caatccagaa cgtaaagaat aattttatta ttccaaaaga
     5701 tgttcctaat gcaaaaacaa atattactgt aaacggagcg tcaaaagttt acaaatatca
     5761 tgttgatgcc aacaaaggtg gttttacaga cgactacgta ggattagtgg agggaaacaa
     5821 aaatatacgc tatccttctt tccaaaaaga atacggtgaa acaaaccttg ttttagaagg
     5881 cgtaacaacc aacaccaaag tcaatattga ctatggaaaa atcggtacgt ataacgggaa
     5941 aaaagtcaat atcaagctag ttctatctaa tattcactta tactcggata cgttgccgtg
     6001 gaatctacta gataacaact atacaaaaac tcattttcga gacgatggct ataaaaatac
     6061 gaatggtgca atgagtaaat ctaaaaaaag aacagtactt tggatctcag acaatctttt
     6121 ctcaggaatt gtttaccatt caacacaaat gaatgtgcag ctagtagcca catatgagga
     6181 cggtagcccc gttcaatttt caggagatac atttatcagt tttaactctt tgaaccctgc
     6241 aggaggaaaa agcacggatc ttaaaggaga atatgcccac tatgacaaaa tgaatacgac
     6301 agattggtat gtcagaaaag atacggttct ttcagaattt aaatctttct acaacaatct
     6361 gaacgtggta ggtggccacc caggaggaag ctctaagctg acacaagcgg ataatgattt
     6421 caataatttg catgataaat taggagatcc gaagtttggt caaggtactg tgtcctttaa
     6481 aatatctgaa gcaaatccga cgtttgtgat tggttcttct aatgttcaaa cctggtttac
     6541 tttatcttct gcgacaatct ttagtgttgt tcctgatcaa cctgaaaaaa caggggttga
     6601 taaaaatgga aataacgtga acgataaaat gttgcaagta ggagacacga ttcaatatcg
     6661 aatcaaacag aaggtgaatc gattaggagt ggatttacta gcggtttacg atcgatttga
     6721 gttaatcgat aatttaccaa aagaagtaaa ttacgtcgat gcacacgttg aaagtggtac
     6781 aaataaaaaa ttcgatgtat ctggtgaagt gacctatgac aaaacaaaac accaggtaaa
     6841 atatgcagcg aaagctgata cattaaaaaa tcgaatgaag tataacggcg aaacttacga
     6901 attagtgatc aatgtaaaag tcaatgaatt ggccaatcaa aatagtgtag ccaaaaatca
     6961 gggaacgtcg atcattaata aagtagaaaa ggatacaaat atcattaccg tttatttccc
     7021 taaaattcca gtgaaagaag tacaacaaaa tggaaaagat gtaaacggac gaaatgacgg
     7081 taagaagggt acgccgacag ctcctttaaa cgcaggatct gaagtacaat atctagtcac
     7141 acaaaaatgg cacacaaaag gcgtagacgc tgcgtcagat cactacaaac aatttagtat
     7201 tcaagatcca attgaagctc gtttgacata taaagaaggt tctgcgcaag taatagataa
     7261 gagtaaagga aaagatatta cttctgaagg cacactaacc tatgatagca attcaagaac
     7321 gctgaagtgg gaagcttccg ctgacttctt aagtaacaat cttttagatg gacgagaaat
     7381 tcagctgata tttacagcta aaactccatt acaatcagaa aaaaatattg ataaccaagc
     7441 cgtagtagca gtagataatg tttctaataa aacaaatgtt gtgacaattg gggttgatcc
     7501 taacttgcca caggtcattg ttcctaaaac aggttctaca catttagtaa cgatttcagc
     7561 ggtcagctta ctattacttg tgttagcaac ttttagttat gcggttctga gatacattta
     7621 aaataaaaaa acgaaagaat gaataaaatg aaaaagttaa taatagtagt tacttccttg
     7681 attgccatga ttgttatttt agtcggatgt agtaatgaaa aaaataaaca aactaatcaa
     7741 gataatggcg tattgaaatc aggaactatg tggaaagaag aagtaggtgg tcttgtttat
     7801 aatttgaaaa ttatagacga gactacctgg gaatactctg agagtgtatg gcatccagat
     7861 cctgtacaaa taacagtcaa gaggcaaaaa gactataaag gtttagaaag atacaaaata
     7921 gtagattcag ctggtgttag ggaatttata aacaaatctg attctttatt tattgttgtt
     7981 ccctatgaga agaatggcgt aaaaaaaata atttttcttg gatctagcaa ggatgaaaag
     8041 cgaacgaaag agaaattgat tcacgatgga tcacaatcca ataaatataa gttacaaaag
     8101 actagcgagt gattgctagt ctttttattt gtcctgaagg aggaatcaca gtggcaaaag
     8161 ctaaaacgcc atttgaaaaa gccgcgtcta aaatcttaga acgccgcggt gtatctgaaa
     8221 cacagtggaa acaagaagtc cttgaaaaag cacaatttga cctattacgg ggaaaagaca
     8281 aggacttaga aggatatatc tatcaacgtg aacgtgaaaa gcttgttttc gatgaaatta
     8341 ttaaacacta aaaggagcga acaattttat gtttgaatca attacaatga attttttaac
     8401 acaaccgaaa gtagtagctg cggttgatat ttttagagca ttacaaactg ccgcaactag
     8461 tttaaaaaac aatctgatga tttttgctgc tgctgcggcc gttgcttcca ttgttattgg
     8521 gggtcttttc ttcctatttg gacgaagagg agctgaaaat gggaagatgc acgtaggcta
     8581 tgtattgatg ggggtaggag ttattttagc agcagcttct attgtggttt cgttatttgg
     8641 attgtttgga caaacacctc aaggattata agaaagtaaa aaagtaggag taagaagtag
     8701 tcgatacttt ttactccttt tttatgaaag gagaatactc atgtacttta cgattgcagg
     8761 caataccaaa acagataaag agttaataaa aaaagcaacg aaggaagtag gaaagcgtac
     8821 ttctttttta ccgaaaacaa ttaaatattc tgtcattgaa acggaagaac agctacatgt
     8881 gttagggaaa gtactggaac acgaaagtcg atcttctgtt aagttgactc tcacgttaca
     8941 tgacacagaa ggaaaaatag agaaagctgg tacagaatac gtttttggcc cactggatta
     9001 tcaaatttca gaaggtttct atcctacatt gatggattta atccgccttg atgtgtttaa
     9061 agaaacggat gaaactatga gtgtggaaga gtcttatcga aacgaaaaac ttttacaagt
     9121 tttagaagaa gagttagaga gcgaccaaag aaaagtgaat caagggagtg aagtcgaagt
     9181 aaatgaagaa gtaccatggg aacgaccaat atttccaaag aaggagtcaa aagaaaaaga
     9241 gacagtctat gttgacgaac aagctgatat tccgactcag aaatcgatat ttgaggaaga
     9301 gaacgatgtg atgggtcaat tggaggtaga tccctttgaa gaaacaatgg aggatgaaga
     9361 gacggccgaa gtagaagttg atccagttga agcgaatgaa gagtcaacat ggactgaagg
     9421 ggattctcag gaatatattg aaccacttat cagtgaagaa gtagaaaaaa acgaaataga
     9481 gatacaaaag gcaactgtat ttgattatat tttggatcaa tatccgccag agcatgaatg
     9541 gatgaaagaa aaaaacaaat tatttttaaa tgagctttat tcgaaatatc aattacccca
     9601 aacctatcaa gcatttttag agagtaaaga agaattaatc tcacagggta aaggcacact
     9661 tttagaacag ttagagtctg tccaatcaac aaattggcat gagcttgcac aagaagattt
     9721 attagccacc tttgaagaac gtcaacaaga aacagatcaa gaaattaatg agtatgcgac
     9781 ggaacagtcg tctaattggg agaaagcaaa agaggaacta aataaagaag aacagcgagt
     9841 gattgaagaa gaagtacaaa aaattaaaga gcgatacgaa aagaaacgcg acaatgcgta
     9901 ttccttgtgt gtagcaaaga tcaataattt tactcagacg aatcaagaag cgttatcgaa
     9961 agaaaaagaa aacttgttaa aagaacgtat taaagaacga aaagaagaat tttaccgagg
    10021 tttgcgtaca gataagctaa agattagcaa agaattaaat gaacaactga ataagctata
    10081 tcaaacaacg actgaagttc ttatggaaaa atacgaaaag atccagcaag aattacaagt
    10141 gcaaattcca aaatggaaaa aagagtatga aattcaacaa caagaattga aagaacaaga
    10201 agaaaaacaa cggcaaaaag aaaaagagcg cgaacaatta gaactaaaaa aacgtgaaca
    10261 ggatcttgcg gaacaacaaa tggcaataga aaaacaacgg ttaaaccaag aaaaggaaaa
    10321 agaagcagct gctcgtaagg aacgtcaaga acaaatggat acattgcgac aagctcagtt
    10381 aaattatcta gcacaacctc aaccaacgcc ttcagtagct gctgttcaaa ccccaatgaa
    10441 caaccaaaca aatctaactc cttcaccaca gcgttccttt aacggatgga tggtgggatg
    10501 tattgcaagt ttaagcttac ttctaggtgg aggaacagta tttgctttta atcatatcaa
    10561 tcaatcttca caggctgatt ctgtggccac aacgacgtca atcaaggaag aagcccaaga
    10621 acaagcaaga aaagagtatg aacaacaatt agaagaatta ttgaatcgta ccaatcagtc
    10681 aacaacagag tcaagcatgg aaaatagcaa agagagtgat tctagtaagg ctaaagaagg
    10741 atcaagcgat tcaactgtac aatcaaacac ttccgaaagt tcagaatcaa atgaggtgaa
    10801 ataatgcgtg ttagagaaac aacgaagcga aaagacaaac gattcaattt agaaaagaat
    10861 aggtatcttt ctcatttcta tcgctatact ccctcaggag aagagctacc agaaaaacat
    10921 gacaaacgca tttcgaaaaa gattttttat agtggacttg tatacctccc tttagagtat
    10981 ttagtaacaa gagtaccaga agttttcaac cgattggaaa ttgttaaggg aagcttacaa
    11041 ggaataaatc tgtttcaatt acaggaaatg ccacaggtct ttcattttga ttcagctggt
    11101 ttttggaatc catttactcc tacaactagt ttgggtacac gtttagcaat ttcgacagtt
    11161 tgtgtggttc cagctgtact tatgggattg aaaatggaca tgtggtttcg tcctctagca
    11221 gatggacaaa aaggggataa tcgattaatg accttaaaag aaatccaaca gatttatccg
    11281 caaatacctg aaacaaaaac tacttttcca ggttatggag gtattccaat cacacattac
    11341 aaaaaatatt ggtacattca aacagatact gttaatacgt gtattgttgg tacctctcga
    11401 tcagggaaag gtcagattga agtgttagcc accattgaca atttatctcg tgcagaaaaa
    11461 caaagttcaa tggtcgttaa tgatccaaaa acagaattat atgttggtag taaagatgaa
    11521 ctagaagcta gagggtatga tgtatatgcc tttaatatca ccgatccact gcaatcaatg
    11581 agtgataatc cattggcact catcgtgaaa tactggaaac gaggagacat agatactgca
    11641 acacagttaa ccaatacttt cacaaatacg atttattatg atgccaacgc ttcagataac
    11701 aaatacttta acgaaaacgc gcagaaagct gtcaatgcgc ttatttttgc gttgttagaa
    11761 caagctgatc aaacaggaga ttactccaaa ttgacaccga ataatctcgt tgagcttctt
    11821 tctgagattg gcggttttaa ttattatcca gatccagaca atgaattcaa acagttgaat
    11881 gccttagatg aatttatgaa tcagttgcca cctggaaaca ttgcaaaaaa acaatatggg
    11941 gcaacgaaaa ttggatctga taaagcgaag ggaaatattt tatcaacggc aatcacggga
    12001 ttgaatccat ttactctaac gaaaattgca aagatgactt ctcaatcaac gattgattat
    12061 aaatcggttg ggtttccaaa atacttagat ttgaaattac atgaaagtct tttaaatcaa
    12121 cgagtcgtag tagaatttta tcataaggga aagaaatttc atgaagaacg tgtcaaagta
    12181 ggctataaag gattttgtga aatcaatttt gattgtcatt tagttgcagg tgatcaagtt
    12241 tgtttaaaat acgatcatca aggaaaagaa tatgtggctt ggtatgaatt ttctcaaaga
    12301 gtattgaaag acgaagaggg taatatcgtt tatcggaaaa aacgaggaga aacccatttg
    12361 ccagaattag aaaaagaagc cgttctaaca ttagatgagg agaaaagtaa cttattagta
    12421 gagtctattc ggatgcacta taccgataaa ccaatggcta tttttatgct tacacctgat
    12481 tatgatccat ctaaccatat cattgttagt atttttctta gtcagttata taaagaatta
    12541 tctacgcaat gtgttaagac taaaggagat aaatgtcacc gcaggattca ttttatttta
    12601 gatgaatttg ggaatatgcc accaatggat aatatggaag gaatcatgac ggtcacagct
    12661 ggccgaaaca tgttgtggga tctgtttatt caatcttatc agcaacttta tgcgaagtat
    12721 ggagaacaaa acgcagcgat tatcaaagaa aattgtcaga cacatattta tattatgtcg
    12781 acagatgata ataccatcga agaattttct aaaaaagtgg ggaataagac ggttgaacaa
    12841 gagaacagta ccatcaattc attaggtatg aatactcata tcaatcgcaa tgttgattca
    12901 gatcgtatct taactcctga aagaatttct acttttttag aaggtgaaac gattgtactc
    12961 gctcctttaa aacgacaaga tttgaaaggt cataaaatac ggccgtatcc tatttttaat
    13021 catggggaaa cgaatcttcc ttatgcttat caatatattg aagatttcaa tccatcgtgg
    13081 gatatcaatg atatagacat acattgtaca catgcggact tggatcttaa ggctttacaa
    13141 attgattatg attatttcct accagatgaa tatgctagaa atctctatca tggactgcat
    13201 gatcaattag aagaaaaaaa cgaagaaaat atgttttata aaatcgttca atctcttgag
    13261 aatgagacgg ctaaaaaatt gttaattcaa ttttacgaag aacaagcagc agatcgactt
    13321 caagaatatg ttgaaaagtt gatcaaaaat aaagaaattt ctgaaatgat tgggaaacgg
    13381 ttgttattgg aatctgaaaa ggtggtgaaa gaatgatcat tggaggaatt ttttctggca
    13441 tagccgactg gtggtcaggc ttattcggag aaggggatgc aaaccccaaa accgtaacga
    13501 aagtcttaca agattatggt aattatctgc agtatcaaga tgtatttagt tggatttgga
    13561 acacttttct gtggggattg attaaaggat tatataatct caatacttta ctagaaaaaa
    13621 ccatttatca aagctttgat ttaaaagact tattgaacgc cgctggggta aatgcactat
    13681 ttcaaagttt gattagtaag gtattggctc ttttttgtgt cgtcacatta atttatttag
    13741 gcttgaaatt ttttatgagt aaacacccac caaaagtcaa aaatatcttg gttaatttat
    13801 ttatggccat gatcttgatt tttggtggga gttctttaat cgatgaaggg ttaaatatca
    13861 gtaaaagctt ttacggagac gtcactgcag caaataaagc agataaaacg ggttcacctg
    13921 cttttcaaat tattcaaaat aatgtgatcg atgtcagtac attactagca actgacccga
    13981 ataaagtaga atccctgcca acagacaaaa gaaatgcttt aacagcgaaa aattttaaaa
    14041 cagcgaatat caatgggatt attactccta aacaagctaa agaaatggcg gataaagata
    14101 agagtggttt atcagattta caaaaggatc ggttaagagc gttacaatac cgattggaac
    14161 tagatgataa tgggaaagaa attcctgttc aaattagtga cgaaggctta gcaaaatatg
    14221 tctatacttc agggtatcgt cgatacagta gtaaaccagg tattatctta gctggtgaat
    14281 cttctttggc ggtggcctat ttatttatcc tatttacgat cgttacttgc attattgagc
    14341 tggtatttaa aaaattctat ttagtgattg ccgcgtcaac ggactttgag acaggccaac
    14401 ggatgaaaag tgcgatagaa gatatttctc aatccttctt gttattggcg tttacgattt
    14461 tagaattacg aatctataca ttaatgcttt caggtatcgg tgatttgcat gcggcaggaa
    14521 agatcaatgg attcttgtat gttgttgctt taattgtgct aactattgcg ctattcaaag
    14581 gctctcaatc ggttacgaag attttcggtg ttgatacgag tctgaaaaac ggcagtaatt
    14641 ctcttcttag catgtttgcc ttaggaaata ttgcgaaaaa tgtgggtagc ggagctaaaa
    14701 accttgcaag tgctggtaag agtggtttaa gccatttaaa tgatattcgt aaaaatggat
    14761 ttggccatcg aaaagatgtt acccctgata acggggaaga acaatcagac gataaagcta
    14821 caactgtacc taatagtaag aaaacagttt ccgaaatgtt cgggaaagcg aaaaatggtg
    14881 tttctaaagc cgcagaaggt cttggttacg tcaatgaacg tgggttaaaa ggaacagctg
    14941 aagatcttac agaaaaagcc aaagacacct tagaagagaa attagacggc acgagagcta
    15001 aagaattggc tgaagctgtg aagaatccat ccgaagcact agaaaaacaa aaagaaaaag
    15061 cttcagaagt caaagaagga ctaaaagatg cgtatggtga aggacaagtt aatgcagcag
    15121 taaaagctaa tacaacaacc gaaaaagaaa atcaagaagg tatagtgatt ccttcagtca
    15181 aagatcacca agaagcgttg cactctaatg aaaattcgat tgaagagaaa aattccatag
    15241 aagaaagaaa ttcagaagaa ggaaaaaatg gacagttacc aaaaactgat ccagaacaat
    15301 atcgctataa acctaacagt gaccttgaaa atgagaagcg aatttcagat ttatcaaaag
    15361 taaatcaaga agacaaagca gaaaatgagg gacagttacc aaaaactgat ccagaacaat
    15421 atcggtatag atctgttaac tccgaaaatg aaaaacgcat ttcagattta ccaaaacgaa
    15481 atcaagaagt acaaacggat gaggattcca tcgttctgcc aaatgataat ggaatcgaag
    15541 ttggaactga aaaatcaacg aaaattggtt tacctaaggc acaaaattta ccaatgaaag
    15601 atagtcgttt gaatcaattc aaggagaatg atcaaagctt tgttcaccaa tcaactgcag
    15661 gtactgttca aatgaaacca agtcgtttgc ctgaaaatgg aaatctgaca actgtttctt
    15721 acaatttatc tgaaagtggt gagacaggga atgcgtccgt tcaaaatgtt gtgacaagag
    15781 aagctgcacc aaaacctatt caaaacgttc atacaggtta caagccagca aatgtggcat
    15841 ttactgcacc aacaaaaata aatgtgacaa gagaaactaa aaacaggaac aatgcattga
    15901 aagaacaact attgagggat atcaaacagg atatcaaacc ataaaaggcc tacaagttag
    15961 gccttttatt tatatgaaaa ggagaaatca attatggata aatatataaa catgaaaaac
    16021 cctccaagat ttagtggaga atggaagttt ttcgcttttt tctttttaga tctattaacg
    16081 cttggtggct gctttttttg ggcgaaaatg gtcaataatc ttgtccactt accactcttt
    16141 tttgcactct tgaattatgg cttatggatt gcgatagcgt tagtgattgt ttggcgaccc
    16201 tataataacc caggtcaacg acaaattttt gcgattatcg agtctatttt ttttgcggac
    16261 aagaaccatt atcatgcgtt agatcctaac cgaaattatc atggtacgta taaggaggat
    16321 gaataaatgc gagtcaaagg acaaaattca gttgaaagga aatccatttt gcagtttgga
    16381 aaaccagaag agcgctctat cttggactta tttccgtata aatcctgtac agaagaggga
    16441 gtcttaatta ctagagaaga tcattttcaa cgttattatc gtgtagtttc tacagacgtg
    16501 gaaggattaa atgaacaaga gaaactagaa cgaatgaatc agttgaccac cgtcatgcgt
    16561 acgtatgtgc caacaattaa gttagttagt ttgaccacag agacggatct aacggaacaa
    16621 atcgtgcaaa agcggcaatt attagataaa aatcgtatgg aacagtcctt aggaagaaat
    16681 ctacaacgat taaaaaaata tgaaaagaaa ttagtcgaag aaatccagga attgaaacga
    16741 gcagaacaag aacgtcctga cttaagcttc tttttcgtca ttgaaggaaa gacaatcaag
    16801 gatttacaaa ccagaaaccg tcagttaatg cgatctagtg gcattttagg gttaaaacca
    16861 ctctacaaaa aagaattgat caagattctg tatcgaatga acaatatgaa tgatgagtag
    16921 gaatggagaa gagagaatga aatatccgtt gatatggtta gaaaaagatg ttccgaagga
    16981 agagaccact agaaaatttc ctcacacttt aagcctgggt aagttgggaa aagggcaatc
    17041 ttttaaccaa gtaaagaatc aaacaagaag aggtgactgt acatgttaga agcaattaaa
    17101 acagcttttt caccacaaaa tgatcaaaaa gtacttgatc cattaaagca actaggaaat
    17161 cgggaaatag aaattttaaa atccaaaggg tatgatttag attttttaaa acaagtgatg
    17221 ccacaaggtg ggttaaattt tgatgaagaa tatgtgacgt atggtaatgg ttattcacga
    17281 tgtgtgacag tttatcacta cacaaaaaat cctacgcttt tttggttggc caatctcatg
    17341 aacaatcctc atacagtggc cacactcgat gttagcacag atgaaaagca aaaagtgatt
    17401 gatcaaatca atcgtgcctt agatgaatta aatgatcgat cagataatga acgaaaagcg
    17461 actgaccgaa ataaaagcgc agaagaatac ctggaactag cggaatatgc tcgtaaattg
    17521 acttctaatg gggaaatttc taagcaagtc aaagtgagag tacatgttta cggaaacacg
    17581 attcaagaag tagatgaacg agcgcaggaa ctgatcgaaa atctaaaagg gatggattat
    17641 cgtgcggtga cttatctgca taaaaccaaa cgagattggc aatcgatgtt taccatgttc
    17701 gatgaacaag ctgaatggtt cggaaatatc aaagggcaat cactaccatc gttaaacatt
    17761 ggcggaggtt tcccgttcca ccaccaaacg ctaaaagatc caggagggac acaatatggg
    17821 gaaaccatga caggcggccc atttgtctgg aatgcgacgt ataaaaatag tgtacggttg
    17881 tctactaata ccttgcttct aggaatgatg ggagctggta aatcgaccgt tcttaaaatg
    17941 atcgcggaag cccatttagc tgcaggagac tttatttggg gctttgaaaa gggaaaagac
    18001 tttattcctt tcttaaagga atataacggt attatggtgc gtttagacgg atctgacgga
    18061 atgatcaatc ctttagagat atttgccaca cggacgtatg atgaagcatc cagtttatat
    18121 gacgatggat cagtcaaaga tttgaagatc aatgaagcag cgtcctatca aacacactta
    18181 gacaaagtgg tctatcaggt acagttagtg agtcctcagc taaaaggaac gatgaaagca
    18241 gaatttaaga cctacttaaa tcgtttttat gaagagtatg gaacagtacc acgcggcttt
    18301 acttcctcaa attcgcgttc aaatacggag acgcaagtca caggtaaaga tccagaagct
    18361 tatccgacgt tcaaagaatt tttagacttt ttaggacaac tggaattacc aggtgcttcc
    18421 caagagaaaa agaatcgaaa agaagaaatg gaatccatcg tagaatcctt atgtgagacg
    18481 tatggcatga tttttgatgg gcatagtacg attcgacacc ttgaccaaca acagttggtc
    18541 ttttttgaca ttgactctat tacaggctta gatcgagggg tacaacaatg tcaaatgtac
    18601 atggctatga cgttgatttg gaatcaggca ttgattcaag gaagaagaca acgacgttta
    18661 attaaagaaa aacaaatgga agaacaagac ttcaaacgct tcttggcgat gattgatgag
    18721 tgccataatg cgattaatcc agattttatt gaaacggtaa attatgtcac aaactttcaa
    18781 cgagaaatgc gtaaagtaga agcaatgact gttttagcta cacaatcccc acaagaaatg
    18841 gtgccagaaa atatgtcttc tgataacttc tcgaaactga agaaagtctt tgaattttct
    18901 tctacgaaga tctttatgcg tatggatgaa tctattttac gtcatataga aggattagtg
    18961 ggtaaatcaa tgacgaactc agaattagaa tccattcctc aacaaaatca aggagacgct
    19021 gtgatcaatt ttggctcaaa agaaaccatt cgtgttcatt ttagtccgaa caaacgtcaa
    19081 ttaaaattgt ttgatggagg aaaataatgg aaaaccaaaa tgaaagttta atcaaacagt
    19141 atgttaagcg tcgtgcaaag cggcgcttat ttttgtgggt gtttggtact tctgcaggtt
    19201 tgattactat tttgatcact gtgtttgtga ccctatttct aatacttgcg gcaggttcga
    19261 ttgataattc ggattcagat tcaagcagtg gtggcgaagc ttttacagga gaatattcgg
    19321 aaggcttacc gatttataaa gaaatcaaag gaagaggccc tttttctgat gagattgcgc
    19381 aatatgctgt aggtgcagca gtgaaatata aattattacc aagtgtgatc ctttcgcaat
    19441 acggttacga atcagcgttt ggtacgtcgg cgtccgcaag aaatgatctc aactattttg
    19501 ggattacgtg gtttgatggg tgtctgtttc ctaaaggaac tgcgcgagga atcggtggta
    19561 ttgaaggtgg ctggtacatg aagtttccca actcaaaagc tgcattttcc tattacggat
    19621 ttatggtagc cacacaatcc aattttaatg cttgtgtcgg aaataaaagc cctggcgcaa
    19681 gtttattgat cttaggacga ggcggttatg ccgctgcagg aattactgaa gatagtccgt
    19741 attatacagg ttgtatgtca attatcactt ctaataaatt aaccgaatat gatgaattcg
    19801 ccatcaaaca ttggggtgaa ggtggcaata acaatggcac aattactggt gaatggacga
    19861 atccattccc tggcagcagt ttagataaaa gttccttcag cggtggtcaa ttatttggaa
    19921 caaatccagg cggtgaattc cgtccgaatg gcttccatga tggattagac tttggttcag
    19981 ttgatcatcc aggaagtgaa attcacgcgg tgcatggagg aaaagtcgtg tacgttggca
    20041 atcctggtat ttcaggttta ggtgcatgtg tgatcgtgat taattacgac ggtttgaata
    20101 tggtatatca agaatttgcg aatagtacag gaaattctcg tgtgaaggtt ggcgatcaag
    20161 tgaaagttgg tcaagtaatc gggatacgag atacagcaca cttgcattta ggtttcactc
    20221 gaatggattg gcgtcaagca caaggacacg cattcacaga tgatggtaca tggattgatc
    20281 cattaccatt tttgaatagc agcaaaaaat agatcaggag aaaaaatatg gaaaataaaa
    20341 ctttaaaaat cgtcttaaca gctgcaatta gcgttagttt aatcggcaat atcgcgttgt
    20401 tttggcagct gaaagaagaa caagagacaa atacctttaa aattgaagaa gtggctaaaa
    20461 acgcgtctga gaagctcaaa aaaaattcct ctgaggcaca ggcgaagatc gacaagttaa
    20521 atcaaaccat caatgagaaa aaccaagaaa tcgaacagct gaagcaacaa gatggcacaa
    20581 aagcaaaaga agaagtaact gaagcacaaa gtaagacggc agaagagttc ggtaaattag
    20641 ccattgataa atcattaagc agaaatgaat taacggaaaa actaaaagat gtcgcaaccc
    20701 aagaagtgat tgacaaatta agtcctgcag acgatgatca ccaacatgat gattacggaa
    20761 gttactcctt tacattaggt gacgtgcaaa cttacgctca aacaagcagt gtaaaagagg
    20821 aacaaaattt tgtcgtattt gttgattata caatcggcaa tcctcaattc aaagatgtca
    20881 aaccacaaaa aataaaaggt ggattaactg tcactgaaaa acaggtagat ggtcaatgga
    20941 aagtcactga ctttagttat ttcactcgtt aggaggaaga aaatgagtaa gaaaaaagga
    21001 gaaagacaac gtttcaaaaa acgaaaaagt tatcttagat ggctgggaat ctttatgatt
    21061 ctcggatttt tgattcttgc tagtccgatt tacacgcatc agaaggtaga cataccagat
    21121 gaagtaagca cgaacgcatt tttaaacacg aaggaactaa cgatggtttc aaaagaaaaa
    21181 ggagcgaacc agcaattagt ttttgaattt gcaatcgacg atgaagatca aagcttatta
    21241 aaagaactgg ctaatcttaa ttatcgcgta gaagtaaaga cagctaaagg ggattatcaa
    21301 gcaataaaag ccaaagtgat taaggtgtct gatgattatt ttgcagtgaa gctatcgcat
    21361 gtaccagaag aatatattgc tatgcgatta accattattc ctgaaaaaat tgatccaaag
    21421 gtggatatgc aagaaccaca agatctgatt tattacgttc acgaagataa ggttaaagat
    21481 caagtgaaag atgaagatta tgaacaacat gcgatcaatt acaaagtgaa aggatacaag
    21541 aaagaacaaa aagcagctca aaaacaaatg gaatctttcc aagcaaccat tgatttgaat
    21601 gaagaattag tgaagaagct aaaagatcaa ttgccttatc aagtcgcaga tgatcaggaa
    21661 aatactgaaa acaagattaa tagctaccag caagaaattg aaacatcgaa aacgcaaatg
    21721 aaagatcaag aagagatcat tcaaaaactt caagaaaaaa ttgatcgtat gacaaaagaa
    21781 aagatttaga aggacaggtg gagtgaaaaa atgaagcgaa caaacttggc tgacaaagat
    21841 actttcgctg agcagaaagt attgattaaa gcctatctca aagttgtaaa agctaaagaa
    21901 atatgtcgag aagtgaattt atctaataca acaatatctg agttgaagaa tggtcgaaag
    21961 aatttagata ctttaaaatt cagatcattt gaagctctat atgtagctgc taaaaaatat
    22021 tttacagctg ataacaaata aaaaacagga gtattttatg tgaaaaaagt atataaaaaa
    22081 tgcttatgaa tcagctatat caccttaacc atttgttaat gagatgggag aaaacattaa
    22141 ccacgattct aacgcaaaca tcaagcacat aaaacattta acactcctcc tttctggctg
    22201 aagatttcaa ccaaacagga agacagcgta tcaattatag catacacttt ttcttaaatt
    22261 catttttcat atgacaaaat atttccttct aatcgacaaa gttagaagga ttttttattg
    22321 tctaaataca caaataacct taatttataa agagcataag gaaacgtggg aacacttttt
    22381 aaaaaaagtg ttccaatagg ctgtgcctat tacgtttctc aaaaataaat gtgggaacaa
    22441 aatatttaaa aataggatag tgaaaggata gtgaaggata gtaaaaggag ggta
//
LOCUS       DAFENC010000042        22440 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.044, whole genome shotgun sequence.
ACCESSION   DAFENC010000042
VERSION     DAFENC010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22440
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.044"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(29..1261)
                     /locus_tag="LP493_002110"
     CDS             complement(29..1261)
                     /locus_tag="LP493_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBL2134253.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1516..2085
                     /locus_tag="LP493_002111"
     CDS             1516..2085
                     /locus_tag="LP493_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL2134254.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2263..2703)
                     /locus_tag="LP493_002112"
     CDS             complement(2263..2703)
                     /locus_tag="LP493_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBL2134255.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2861..3625
                     /gene="map"
                     /locus_tag="LP493_002113"
     CDS             2861..3625
                     /gene="map"
                     /locus_tag="LP493_002113"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HBL2134256.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3657..4580
                     /locus_tag="LP493_002114"
     CDS             3657..4580
                     /locus_tag="LP493_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HBL2134257.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            complement(4805..5044)
                     /locus_tag="LP493_002115"
     CDS             complement(4805..5044)
                     /locus_tag="LP493_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2134258.1"
                     /translation="MSKDYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFY
                     HSESGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(5049..5468)
                     /locus_tag="LP493_002116"
     CDS             complement(5049..5468)
                     /locus_tag="LP493_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBL2134259.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            complement(5695..6933)
                     /locus_tag="LP493_002117"
     CDS             complement(5695..6933)
                     /locus_tag="LP493_002117"
                     /inference="COORDINATES: protein motif:HMM:NF017760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2134260.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
     gene            complement(7040..7675)
                     /locus_tag="LP493_002118"
     CDS             complement(7040..7675)
                     /locus_tag="LP493_002118"
                     /inference="COORDINATES: protein motif:HMM:NF012655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL2134261.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINETKLSKG
                     AIYHHFDSKEDILKAIFQRIGNENAVIFAKIRDNDSLNGLEKLREIFKTAVFNSNQSV
                     LLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQGIKDKSLEIENSHEIAEVIMV
                     LSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLLDEETISAFIQFCK"
     gene            complement(8017..8652)
                     /locus_tag="LP493_002119"
     CDS             complement(8017..8652)
                     /locus_tag="LP493_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2134262.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            9164..10306
                     /locus_tag="LP493_002120"
     CDS             9164..10306
                     /locus_tag="LP493_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBL2134263.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEVIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYRNGGAECRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVEFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDISDVIESEGVFYE"
     gene            10299..10505
                     /locus_tag="LP493_002121"
     CDS             10299..10505
                     /locus_tag="LP493_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBL2134264.1"
                     /translation="MSNTQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEKVIDKLDAI"
     gene            10584..11777
                     /locus_tag="LP493_002122"
     CDS             10584..11777
                     /locus_tag="LP493_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL2134265.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDALGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRTNVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVIENDTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQRVINSRPKIKSIEVDGHSGFVFINPKGNPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            11982..13121
                     /locus_tag="LP493_002123"
     CDS             11982..13121
                     /locus_tag="LP493_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HBL2134266.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            13114..13914
                     /locus_tag="LP493_002124"
     CDS             13114..13914
                     /locus_tag="LP493_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL2134267.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            13914..14741
                     /locus_tag="LP493_002125"
     CDS             13914..14741
                     /locus_tag="LP493_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBL2134268.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            14719..15453
                     /locus_tag="LP493_002126"
     CDS             14719..15453
                     /locus_tag="LP493_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL2134269.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            15553..16419
                     /gene="rfbA"
                     /locus_tag="LP493_002127"
     CDS             15553..16419
                     /gene="rfbA"
                     /locus_tag="LP493_002127"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBL2134270.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            16433..17005
                     /gene="rfbC"
                     /locus_tag="LP493_002128"
     CDS             16433..17005
                     /gene="rfbC"
                     /locus_tag="LP493_002128"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HBL2134271.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            17027..18055
                     /gene="rfbB"
                     /locus_tag="LP493_002129"
     CDS             17027..18055
                     /gene="rfbB"
                     /locus_tag="LP493_002129"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBL2134272.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            18153..19004
                     /gene="rfbD"
                     /locus_tag="LP493_002130"
     CDS             18153..19004
                     /gene="rfbD"
                     /locus_tag="LP493_002130"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HBL2134273.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            19038..21071
                     /locus_tag="LP493_002131"
     CDS             19038..21071
                     /locus_tag="LP493_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134274.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            21115..22395
                     /locus_tag="LP493_002132"
     CDS             21115..22395
                     /locus_tag="LP493_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HBL2134275.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
BASE COUNT         7070 a         4007 c         4446 g         6917 t
ORIGIN      
        1 tattttttgc atgtgtgcga aagtatactc aagcccaatc gccatttcgg aaaatcggta
       61 ctgtagagcc atcttcacgg attccgtcga tatccatctt gtcagatcct accatgaaat
      121 ctacgtgggt ttgacttcta ttcaatccag cttctgctaa ttcttcatcg gacatttctg
      181 taccgccttt cacactgaag gcataagcag aacctagtgc taagtgattc gatgcgtttt
      241 catcaaataa tgtattgaaa aagatgatgc cagattgaga aataggtgaa gggtcaggta
      301 caagtgcgac ttctcctaaa cgacgcgcac cttcatctgt atcaagcagt tttgctaaga
      361 catcttctcc ttgttcggca gaaaaatcaa caacttttcc atctttaaaa gtaaatttca
      421 tacccgagat gatggtgcca gcataactca gtggctttgt acttgaaatg taaccatcta
      481 ctcgatgact gtcaggtgct gtgaacactt cttccgtcgg catatttgcc atgaattttt
      541 ctccacgagc attatagctt ccagcgcctt cccaaagatg gtttttaggc aatccgataa
      601 tgatatctgt accgggagca gtatagtgaa gggcagaaaa ttgttctcga ttcaattctt
      661 ctgctttttt tgctaatttt tcatcatgct tcttccatgc taagacaggg tcttcttcat
      721 agacacgagt cgttttgaaa atctgatccc ataatgcctc aacttgtttt tcttctggca
      781 gttctgggaa gacttttgct gcccattgtt taccagccgc agccacgaca gtccaactga
      841 ctttatttgc ttgagttgcc ttgcgtaaat tcattagtgc tttgccattc gctgattgat
      901 aagacgctac tcgatggcta tctacaccag caaatgcatc gggatcggca gaaacaacgc
      961 tgatcctgct tgctcctttt tcaagccatt catccgcttg atcgatttta gattgtggta
     1021 cattctcaat acgatccgtt gcagcatgta aaagaaattc tctttggatc tggtcgtcag
     1081 tccattgaac gataacctca gcggctccta gtttataagc ttcttgtgtg atcaatcgag
     1141 caaggggtgc ctgttccacg ctgatctgta aaacaactgt gtgtcctttt tctgtggcta
     1201 cgccagtttc tgcaattaag cgtgcatatt tttttagaag ttcattaaaa tcagataaca
     1261 taataaaaat tcctcctcac cattttttct ggtaactatt agcatgatac catttaatta
     1321 tgattcaaac aatgaggctt taaataaaaa aaggaggtta tttttttaag gttaagtttc
     1381 atgatatatg ttactacttg ctatttcagc ttgtgaagaa aatcaaaaac taattttgca
     1441 tatcaaaaaa aacatgttac aatgaaatta atcaatggtg gaagcgttat aaaaaaatta
     1501 aggagattaa aaaatatggc aagaaaaaag acgattacta gagaacagat tttggcagct
     1561 gcttatgaag tagctgccac cgatggattt acacgattta ctgcgagaaa catcgcgaac
     1621 aaaatgaatt gttccacgca accgatttat cttgagttta aaaatatgga tgacttgaga
     1681 caagctcttt ttgagcagat ctatgatcat ttacaatatg aagtgttcac tgttgagcat
     1741 acagggaata cgattatcga tcttgctttt aattatatcc attttgcaag aagagagaag
     1801 aagttgtatc gttcactgta cttagaagaa tatggtggag gaaaagagat gcagaatttc
     1861 tcttatactt actttgtgaa tacagtgaaa cgcgatccag cttatgtgaa tctttcagaa
     1921 gagcagatcg aatctttgta taatgggaca tggatcatag ctactgggat cgcagctttg
     1981 atgtcttcaa gcatcatcca tccaactgat gaacagattg aaaagatgat ccaagacagt
     2041 atagatgcta tcttgaaatt caaagaacca atcgaaatcg attgaatata ctcaaaagtt
     2101 ccacaaatca gtaggtaaca agagatgtgt caaaataagg aaaagttcgt ttttcttaca
     2161 gcgtatgcat ttttaactcc cgaagaactc ttccatgaat gcaatgaata aaagagccat
     2221 acagattgaa taaatctgga tggctctttt attgcaagta tattaaattt ttgcgactag
     2281 ttctttagcg aaagcttcta aattttcgat atcttcttct tcagcattca gatccacttt
     2341 aacattttcg gctccttttg atgcgcctgt ttttgcaaaa gcagcatcga aatcatccac
     2401 cgatttgcag aattcatcgt aaaaagtatc accagatccg cagacaccgt aaatttttcc
     2461 caatagatcc aattcttgca agtcttcata aaagtctacg atctcatcag gcagatcgcc
     2521 atcatcgtat gtataagtag ctactacgca aatatctgcc tcctcgaatt catctgcatc
     2581 tacttgggta cattcgttga tttcgacttc gatatccaga ttttcaaatg cttctgcaac
     2641 aatatcggcg atttcttcag tgtttcctgt catgctagca tatacgattt ttgctaaagc
     2701 catgatgtgc ctcctcgttt ataattattt aacaattatg aattatacca aaacatcatt
     2761 gaaaagaaaa taaaacctag agacacctgg ggaatgtcat ttggctaaat gtatgccgct
     2821 atgttaaaat gagagggatt tgtaaaaagg agacgaaaat atgattactt taaaatcagc
     2881 acgtgaaatt gaaatgatgg cagaatctgg agctttatta gcagatgtac ataaaaatct
     2941 gcgtgatttt ataaaaccag gaatcacaag ttgggatatt gaggtatttg tcagaaacta
     3001 tatcgagagt catggcggaa ttgctgcgca aattggcttt gaagggtatg aatatgcgac
     3061 ttgtatcagt ataaatgatg aaatttgtca tggattccct cgtaaaaagc ctttgaaaaa
     3121 cggtgatttg gtaaaagtcg atatgtgtat cgatttgaaa ggcggcattt ctgattcttg
     3181 ttgggcctat gtagttggag aatctacacc tgagatcgac cgattgatgg aagtaacgaa
     3241 gaaagctttg tacatcggta ttgagcaagc acaagtaggg aatcggattg gtgacatcgg
     3301 tcatgctatc caaacttatg tagaaggcga aaatctagcg atcgttcgtg attttattgg
     3361 tcatggcgtt ggtcctacga ttcatgaaga accagcagtt cctcattacg gagaagctgg
     3421 aaaagggttg cggttgaaag aaggcatggt tatcacgatc gaacctatgg ttaataccgg
     3481 aacttggaaa atgaaaatgg atcctaacgg ctggactgcg tatacaagag acggcggact
     3541 ttcttgccaa tatgaacata cattggctat tactaaagat ggtccaagaa ttttgacatc
     3601 acaaggagaa gaaggcactt attgatctat ccagtcaata ggtacgggag aggtacatga
     3661 aagtttggaa caaaataaaa caaaatgaaa atctgatgcg ctttattgag acgactcaaa
     3721 agcgcatcac tgattcagaa atgagtacga cctctgtcgt cgttgcttat tatttactct
     3781 tgtctttatt tccattgatt attgcttttg gtaatatttt accgtttctc cacatcgatc
     3841 aagagactgt actgacctat ttacgagaag tgattcctga gaccgtttac cagtttatcg
     3901 gtcctgcaat caaagacctt ttgacacaaa gttcaggagg cttgttatcc gtttctgcat
     3961 tagcggcttt atggtctgca agtcaaagta tcaatgcttt gcaaattgcg atgaataaag
     4021 cgtatggcgt agaaaataga aaaaattttt tgatcgtccg tttcttctca ctaattgtca
     4081 ttgtcttgtt catgattgct attagtgggg taactatcgt tcttgggttg ggacagctga
     4141 ttttggatgc tattcagcca atcgtacaaa tacccgtgaa ctttatcgat cagttccaaa
     4201 ctttgaagtg gccaatcaca ttggtagctt tatttgtcat catgttcttg atttatttaa
     4261 ttgtccctaa tgctcagttg aagttgaaga cgatcattcc gggcacgatc ttcgctactg
     4321 tcggctggat gctgttatca caagtgttta gtatctatgc taggtatttt gcaacgagga
     4381 tcagcggtta tcagatcata ggaagtttta ttgtactcat gctttggctt aattttgctg
     4441 ctacgatcat cattttgggc ggaatcatca atgcagttgt tcaagaatac gtgacgggtc
     4501 atcaaatcaa aaaacgtcga gatccaagcc gaaaatggtt caataaattg aaaactaaat
     4561 tttctcataa aaaaaagtag aaacaagagt tcttattgta aatttatatc agtaatttat
     4621 ttgaaatttt atatctaatt ttcaattatc cgcataaaca ctatacattc aagcattttg
     4681 aagtatagaa aaacactcat cttaccacga atttaccacg attgaatgag ccttgatatg
     4741 accgtaaaac tactaaggga gatagcacga aactgtgtat ctcccgattt ttttatacag
     4801 ttgattactt cactccgatt tcaaatttca atattgcttt catcatgtct gtatgaattt
     4861 ctccttttag ttcttcatca acctgcataa tgattttacc actttcagag tggtaaaaag
     4921 gacgcaagca taatttagaa atataaccgt cataaaactt caaaatctct ttaactgcca
     4981 tttcatctcc gcttgacgct ttgcaaatca attcaaaaga gggatagcca taatctttac
     5041 tcatttcttt acttcctttc gctcaaaagc atttttaact tccttagtcc tctagttctt
     5101 ctactgcaaa tagcagaacg tgatacatgg tacagttctg aaatttctct gtcgttcatt
     5161 ccttgaaaat aacgtaataa aatcgcacta cgctgttttt ctgacagtct atgtaaaact
     5221 gtaccaagtg tttcatcaga tacataaatt gtaaagtgca agactttaaa tgatacacaa
     5281 tcataaaaac aggtatcaat cgttccacgt tcaacttgtt tcgtttcggc tatttcacaa
     5341 aacaatactt cacgtttaga atgtcttgca agctgtctgt ttcgactttt cactttgttc
     5401 ttaatgacaa tcagcattaa agaattgaac tgtaatctga cgatatgctc gaaagaagat
     5461 gtcctcataa tctcaccccc tttctgctaa tgctgaaata tataaacgga ataccgttta
     5521 taccctttag aaatacagaa aaatggtaag aaaaaagccc acacaaaaca tatatttgtg
     5581 cgagccttaa atactgcaat attactcttt cttttataac actatccttt tagcagattt
     5641 caaattttct tttatatatt gtttttagcc taacatacta tttaacccct tgtattatat
     5701 ctctaacttt tgaaaaattc tttttgaata tattgaaatc atgattgaag caatagaagc
     5761 tacaaacata acaacccatg tttcttgtat aaatacatcg aataaaatac cgtaaaccat
     5821 ttgtccaata ggttgaccgc acatagcaac tgctaccagc gtagccatta tctttcctac
     5881 taattgcggt ggtgtttgtg tctgaacaag agtgtaaatt tgaacaacaa acatagtaga
     5941 tacacccata gccacaaagc acatcactgt aactacccag taggaaacta ttgcaggcaa
     6001 ttctaaaaat agcgaaattc ccataagtaa aacagaaaca gaacaaataa gtaacaaggt
     6061 ataaaggttt tttagtttta actttgaagc aacaagagct gttaaaatac caccacataa
     6121 accacctaat gataatgctg attgtgaaaa accatatagt gtatctggca tttttaaaac
     6181 ttcagaaatt aagataggca gaccaacaat taaaacagca cttaaaacca aattgaaaat
     6241 gcaaaccaaa aagattacgg atataaaaat gggtttctcc tttttcaaaa aggtataact
     6301 atcttttaaa tcgtttttag caactgcaat tacacctact tcacgaggtc ttttttggtg
     6361 tggaatatgg ataaaaattt ccataatggc tgaaaaagta aaacatataa tactaacaat
     6421 taaaatggga ttgataccat aaaattgaaa aactactccg cttatagctg gtccgataaa
     6481 gtttgctaaa gtatttactt gatttattat agcattaccg acggtaagtt tatctgatga
     6541 taccaataga ggaatacttg cttgtaccgc tggttgatat gcaccagaaa taccataaag
     6601 taacatcaaa gcaacaataa acaaaggtat gataggaatt tttcccaatg acaaataaaa
     6661 tactaaaatt atgattgctg ttacaaaatc tagtatgacc ataatgtttc ttttatttgt
     6721 cctgtcagca ataataccac ctaccagcga caaaataacc ataggtaaaa aagagcaggc
     6781 tgtagcaata ccaaacaaag ctgatgaacc agtttctttt aacaaatagt acggtaatgc
     6841 aaatcgtagg atagcgtttc caaataaaga aattatctgt cctataacaa caagtataaa
     6901 atcacgatta aaaagttttt tttctgcttg cataaaatct ctccttttta tttaatcaaa
     6961 cagaccgtcg gtttatataa tggtttaaat aaactgctct tttatagagc agtctatcgt
     7021 atagggataa caaatacagt tatttacaaa actgtataaa tgcagaaatt gtttcttcgt
     7081 ctaataatgt gtctatgcct attccattta aaagggcatt gaatgtattg caacgttttt
     7141 ccataccctc tttatccgtc atttcaacta atgggttgag ccatacatta cttaatacca
     7201 tgataacttc tgcaatttca tgtgaatttt caatctccaa agacttatcc ttgatacctt
     7261 gttctaaaac gggttcaaca aattcaggta ctacaatttc atacatttgt tctatttgca
     7321 tagcaagaaa acgaggattg tttaatagtt gaggagaaac tgtcaataaa acgctttggt
     7381 tagaattgaa taccgctgtc ttaaatattt ctcttaactt ttctaaaccg tttaaactat
     7441 cgttatctct aattttagca aatattactg cattttcatt tccaattctt tgaaaaattg
     7501 cttttaaaat atcttccttt gaatcgaaat gatgataaat agcaccttta gaaagttttg
     7561 tttcattgat aatatcttgc aatgatgtgt tatcatatcc tttttcacaa aacatttttg
     7621 tagaaacatc taaaatgagt tttactgttt cttctggata tttatttcgt gccataactt
     7681 acctccaata caaaccgttg gtctgattaa agtatatctt agtattttat gcttgtcaat
     7741 ataaagactt gcaattttat aaaaatgcag aatgcaagcc tttttcattt attctacaat
     7801 cttccagttg ctttccttat gcggtgtcaa ttcatactgt gatacctgcg ttgcctttgc
     7861 ctgatttacc acaaatcaga ttttatccct ttcttcctct tgattgccca caacagaaaa
     7921 gaaaaagccc tgtcaagagc tttgccacca ttggtggtgc tttgcactct tgatcgggct
     7981 ttttgtttgc tgtatcttct cgcaagagga aaaaagttac tcgtcctcat catcaaaatt
     8041 gttattcctt aatacttctc gtaacagttc catatcttct tttgagttcg ggtttatcat
     8101 tttcacgact tgataaggtg tcttatactt atgtccctct atgctttccc caaacatatc
     8161 catactgtat aaatcatcat agcggtctaa taatttttga aacttcaaat gctggataaa
     8221 ttctttgatt gggtaaaggt cggacgcttc aatgcttttc ccgttgatat agtctgtaat
     8281 atattcccgt aacttttcta actcatattc cagccattct tcctcgctgt caaagaagtt
     8341 atcatagtgt ccatgtttca gttctgcatt tagacgttct tcggctctta aaaactgaca
     8401 gacttccttt tcagattgat tgacatactt ccattctccc gacaacaatt cattgggcgt
     8461 aacgtccagc acttccatta tcttttccag cgtttcatag gcaggatagt tcaaccctct
     8521 ttcaatcttg gaaaggctct gcatattgat accgattttg tccgcaagtt cctgttgttt
     8581 cattccccta aattttctta tggtctgtat attatttcct aaatggctta ttttcattgc
     8641 ataaccctcc atatctcgtt atatcttcgc tattataagt ctatcatgct taatatgatt
     8701 tgtaaaggca aaaaaagata ttgacaaata agcatataag aattactatg ttcttgtaat
     8761 cgaataagca caatagaatg aaatataaaa acattcaaaa agaaatacct atctgattaa
     8821 atccgtagat atgaatatcg gttgaaatgg aacttgttag aaaaggcaaa acagaacttg
     8881 ctgacaaagt atttctgaca cggtggcgga agcctctcag gcttaccgcc atgacacctt
     8941 gtgtcaaggg gaagaaatgc tttgtcggct ggcgagcctg cgagccttgt ctgtgccccc
     9001 gttatctaac aggggggcac tatttcacaa aagacaagtc aaaaaccata cacccccaaa
     9061 cctgtgagta gtaatgagag gttttaagaa gatagtacat atcacacttt ttgaaaggtg
     9121 gtttacaggt atttcaaggc tattgtggga ttggaggaat acaatgaaca atttagaatt
     9181 tgcacttgaa atgaagaaca aacgtcttgc cagcggtctt tcacaaggag aacttgcaag
     9241 tcttacccat gtatcaagat atagtatcaa ccgctttgag aacggaaaag ctaacgccag
     9301 caaggaaaca cagaacatta tcctgcgttg tctgaattac tatatctgcg ataagccttt
     9361 ttatctgctc gttgattatc tgtctgtccg ttttccaacg actgacgcat tggaagttat
     9421 ccgaaaggtg cttggcatga aagcagatta ttttatccat tatgactatg ggtattatgg
     9481 ctataaggag cattatgctt acggggaaat caaggtcatg gcttctgatg atgaacacat
     9541 gggcgtattt ttagaattaa aaggggcagg ctcacgcaac atggaatatg tcttacaggc
     9601 acagaacagg gactggtatt cattcttaaa ccgctgtctt gactgtggcg gtgttatccg
     9661 acgttttgac ttggcaatca atgatatgtg cggtctgctg gatattcctg tgctatctga
     9721 aaaatacaga aatggtggtg cggaatgtcg ctgtaaaaac tatgaaaatg tacaaggtgg
     9781 aaaattaagc ggaaaaaacc gtaatttagc aagtaccctt tatatcggct caaaggcaag
     9841 cacaaaatat ttctgcctgt atgaaaaaca aaaggaacag gcaacgaaaa agaaacatac
     9901 cgatattatc aaccgttttg aaattcgtct gcgtgacaaa aaggcggtac aggcagttga
     9961 agaactgtta ttgacgtata accctcatgg gctggtgttt tatctcatta ccgattttgt
    10021 ggaatttcct gactatccat tgtgggagat attcatttcc catgacagtt taccttttga
    10081 aatgaaccct gtacctgtca atatggaacg cactctgcaa tggctggaaa gacaggtcat
    10141 gccgtcaatc gtgatgatag aggaaatcga caggctgaca ggttcaaact acatgaaaat
    10201 gattgatgaa tgtacccacc tttctgaaaa acaggaaatg cttgtggaac agatgtgtac
    10261 ggacatatca gacgtaatcg aaagtgaggg ggtgttttat gagtaataca caggatattc
    10321 ccgtatggga aaaatacacc cttaccattg aagaagcgtc aaagtatttc cgcattggag
    10381 aaaacaagtt aagacgattg gcagaggaaa acaaggacgc tggctggctc attatgaatg
    10441 gcaaccgcat acagattaaa cgccgacagt ttgaaaaggt tattgataaa ttggacgcaa
    10501 tctaatgcaa atgagccttg tatgtgttat gatgaacaca agtcatatca aggctctttc
    10561 caacaaggaa aggagcagac accatgaaag aaaaaagacg ggataacaaa ggtcgtatcc
    10621 tgcatactgg agagagccaa cgaacagacg gaaaatactt atataaatat gtagacgcat
    10681 tgggaaacac aaaatatgtg tatgcttgga gattgacacc cacagacccg acaccaaagg
    10741 gaaaacggga aaaaccctca cttcgagaac tggaacagca gataagacgg gatattgagg
    10801 acggtatcga cagcacaggc aagaaaatga cgctttgcca actctatgcc aaacagaacg
    10861 cacagaggac aaatgtgaag aaaagcacac agaaacaacg ggaacaactc atgcggttat
    10921 taaaagagga caagttaggt gctaggagca ttgatacgat aaaaccctct gacgctaaag
    10981 aatgggcgtt acgcatgaaa gacaaaggct tttcctacaa taccattaac aaccataaac
    11041 gctcgttaaa agcgtcattc tacatagcca tacaagatga ttatgtgagg aaaaaccctt
    11101 ttgatttcaa gctaagtgaa gtcatagaaa atgataccaa agagaaagtc gcattgacag
    11161 aggaacagga gcaagcctta ttgtcattta ttaagacgga caacgtgtat cacaagcatt
    11221 atgatgatgt gctgatactg ttaaagacag gacttcgtat ctcggaactg tgcggactga
    11281 cagtagccga cattgatttc aagaatgaag ttgtgattat cgaccaccag ttactaaaga
    11341 gtaaggaaca gggctattat attgaaacgc ctaagacgaa aagcgggata aggcaagtgc
    11401 cattaagcaa agaaacgata caggcatttc aacgggttat caacagccga ccaaagataa
    11461 agtcgataga ggtagacgga cacagcggtt ttgtgtttat caatccgaaa ggtaatccaa
    11521 aagttgccat tgattataac gccttattta tccgtatggt aaagaaatac aacaagcacc
    11581 acaaggacaa tcccttgcca catattacac cgcatacgct acgccataca ttctgcacaa
    11641 ggctggcaag caagaacatg aacccgaaag atttacagta tatcatgggg cattcaaaca
    11701 tcagtatcac aatgaactgg tacgctcatg cgtccataga taccgcaaaa tcagaggttc
    11761 agcgtctaat cgcatagaag tatttaccac gattttaacc acgattgaca gggaaaatat
    11821 aagaagatag acctagatat gcgaggttta ccacaaaagc aaaatgcccg tagagccgat
    11881 aaaataaggc tttgcggaca tttgagaaga tataaaaaga tagtcaaaaa gacatatata
    11941 atttataata attatgactc ttaattaaag taggtgccca tatgcttgtt tcttttagta
    12001 tggttataag attttttctg acaattttat tatcactgat attaacacct gtattcaaaa
    12061 tcatttcagt acaaacaggt atggtcgaca aaccaaatga aagaagaata aataaagttc
    12121 caatgccttc agcgggcgga ctgcctatct ttatttcatt tgttatatcg actttattct
    12181 tattccgtaa aattatccct caatcgtata ttgtaccgat cttgattgct tctttagtaa
    12241 tcatagtcac aggagtgctc gatgataaat atgagctgac acctaaacaa aaaagtatag
    12301 ggatcttgat tgcttctctt attatttatt ttgtagcaga tatacgtatt gattccttca
    12361 cgcttccttt tattggatat atccaactag gctggcttag ttttcccgta acgatttttt
    12421 ggatcttcgg tatcacgaat gcggtcaatc tgattgacgg tttggatggg ctggcggcag
    12481 ggatttcatt gatcggttta attacgatag gaatcattgg atattttttc ctccatgctt
    12541 ctacagtgta tattccagtt gttattttct gtcttgtagc aagtattatc ggtttttttc
    12601 cttacaattt ttatccggca aagatttatt taggcgatac aggagctcta ttcctagggt
    12661 ttatgatggc cgtcctttca ctacaagggc tgaagaacgt gacttttgtt tcatcgattt
    12721 ctttgctgat cgtcatggga gtgccggtaa cagacacgtt ttttgctatc attaggagaa
    12781 aagcaaaccg tgtttctttt tctacagcag ataaaaaaca tcttcatcac cgactaatca
    12841 gtttaggctt tactcataaa ggtgctgtcc tgacgattta tgcgatggct ttgatgtttt
    12901 ctttcacagc tatggtcatg aattatactg gaagaatcgg aacgatcata ttgattattg
    12961 ccatgttgtt tgctgcaatt ttattatttg aattgattgg tctgatcaat gagaaacatc
    13021 agtttatttt aaaaacattg cgatttttag ggaataaaga gtaccgtacg caagtaaaac
    13081 agaaatattt gaagaaatgg aaccgtcata tagatgaata acaaattaaa ccagccgatc
    13141 cttattagta ttgtgacggc aaacagtgat aaaatttttc ggacactaga taattttatt
    13201 tcaactgtaa aagatgaaac agcagtaaaa atccgaattt ttgacaacaa ttcacttccc
    13261 gagtacaaaa aaagactaac agagtatagg aaatatccct acatcgatat ctattttcat
    13321 gatgaaaatt ccggatttgg ttatggacat aatcacaatc tgatagctag cgattctcgc
    13381 tatggcatta tttgtaaccc agatatttta gtggatgaag agacagttac agcattggtc
    13441 ttgttattga aagaacatcc ggaatgtgcg atgttagcac ctaagattct taatgaagat
    13501 ggaacaactc agcacctcat ccgtgagcag ctggctgttt ttgattacgt tttgcgcttt
    13561 gtgcctttca aatgggtcaa aaaaaagttt gacaaacgac tggctgtgtt tgaatgccga
    13621 ggattgccta ctgatgctaa tagttatgta cggatgatct caggtagttt tatggtagct
    13681 gatattgata aatttaaaga gataaagggg tttgatgagc gtttcttcat gtactttgaa
    13741 gacaacgact tgtgtttgag ttttgaaaaa gcaggttaca agttattgta cacacccttt
    13801 tatgcagtta tccattttta cgggaagggt gcgcatcgaa atgcaaaact gtttcgcgtg
    13861 tttttgactt ctatgatgaa atttttcaat aagtgggggt ggcgtttttt ctgatgaaac
    13921 cagaaatatt agtagtcgtt gtgctttatc agcaactatt cagtcaatct ccagcttatg
    13981 gaccattaag caaagcactt agcgaaaagc aaattcagct tattatttac gataatagtc
    14041 ctcaaaggca gcaaaatgag ctgtttgaaa aagaaaatat cgtttatcat catgatccgc
    14101 aaaatcctgg tttagcggtg gcttataatt ttgcgttgtc tcaagcagat gaaggaacac
    14161 gttgtctcgt cactctggat caggatacga ggctagtcga cgattatttt gaactattgc
    14221 gtaaagtaac ctttacagat gaatgtgttg ctgcagttcc gatgattttt tctgggagcc
    14281 gacaagtttc tcccctatat tcagatcgtt atatcaatcg tacagctcaa gcagtagaag
    14341 ttgaaggccc aacagctgaa cgaatcatgg caatcaattc aggtgttgcc tggtctgtca
    14401 aatttctaaa aaagattggc gggtttaatc ctgctttttc tttagatttt ttggatcatt
    14461 ggctgttttg gaaagtggat cagttggaaa aaactgtgga gatccttcct gtacgaatgg
    14521 aacatgatct ttcggtttta gactatgaaa aagtttcaag taatcgatac cgttctattt
    14581 tacaagcaga aaatcgattt tatcatgaat atgatcaaag gcatttatcc agtcaccgac
    14641 gacaattatt gttaagaaca gctaaacagt tcttgaccgt caaaaaccgg catatctggc
    14701 ggatgacttt gcgctcatat gttaagaatt ggaaggtgtg aattcgtgcg ttcggtttgt
    14761 atagctacct ttaatggagg cagatattta agagagcagt tagatagtat tttatctcag
    14821 ctttcagcag aagatgaagt agtcatttct gatgatgggt cagtagatga tacatgggat
    14881 atattaactg aatacgcaga aaaagataag cgaatccagc ttttttcggg gcctcgtcaa
    14941 ggattgatcg ctaattttgg ttatgcgatc cagcagacga aaggagatct aatctttttg
    15001 gcagaccaag atgatgtttg gttggagaca aaagtgaaaa agatcactga ctattttgag
    15061 cagaatccgg atcagctagt agtagtttct gatttaatca ttgtggacag cgagctgcaa
    15121 gagatccatg attcgtattt ttcgtttcga aattccaaag aaggatggct taataatgtg
    15181 ataagaagtc actatattgg tgctggtatg gctttccggt cttctttaaa acccgatatt
    15241 ttgccgatcc cgtcagaagt gccgatgcat gatatgtgga ttggtttgct gggaggaaag
    15301 aagactgggt tcctaagaga accgttaact ctgtaccgaa gacatgattt aaacgcgagt
    15361 gagattgaaa cacattctaa attacggcaa aaaatttctt ggcgtgttca tctgattacg
    15421 gcgttgatca aacgaaaatg gtttaaacgt tgataaaaga tgtttaaatc cttaatattt
    15481 ccatgacaaa tataacaatt gatgagataa taacaaagtg aaatttgaaa tcaaaaagga
    15541 gagcagatat ccatgaaggg aatcattctt gctgggggca gcggaacacg tctgtaccct
    15601 ttaacaaagg caacatcgaa acaattgatg ccgatttatg acaaaccaat gatttattat
    15661 ccaatgtcta ctctgatgtt ggcgggaatc aaagaaattc tgattatttc aacgccacaa
    15721 gatacaccac gtttcaagga attatttgga aacggaaatg atttaggact gcagatcgaa
    15781 tatgcagtac aagaaagtcc agatggattg gcacaagcgt ttatcattgg agaagaattt
    15841 attggagatg atagtgtctg cttggtatta ggggacaata tttactatgg tggcggtctg
    15901 tctaaaatgt tgcaacgagc agcttcaaaa gatacaggcg cgacagtatt tggctatcat
    15961 gtcaatgatc cagaacgctt tggtgtagta gaatttgatg agaatatgca agctttgtcg
    16021 attgaagaaa agcctgctca gccaaaatca aattacgctg taactggcct ttatttttat
    16081 gacaatgagg taatttctat cgctaaaggt atcaaacctt cagaacgtgg agaactagag
    16141 attacggatg tcaataaagc atatttggat aaaggaaaac tatccgtaga acttatggga
    16201 cgcggatttg cttggcttga tacaggaaca catgaatcat tgcttgaagc atctaccttt
    16261 atcgaaacaa ttgaaaaacg tcagaactta aaagtggctt gtttggaaga aattgcttac
    16321 cgtatgggct acatcgataa ggaacaattg ctggcccttg cacagccatt gaaaaaaaat
    16381 caatacggtc aatatttatt gaatttggcc gctgaataag gagtccttac agatgaaagt
    16441 aacagataca aaattaacag atgtcaaaat cgtagaaatg gacgtctttg gcgatcatcg
    16501 cggtttcttc acagaaagtt attcaaaagc aaaatttgca gaacatggat tgaaatatga
    16561 ctttgttcaa gacaaccatt cactatcagc tgaagctggt gtccttcggg ggcttcattt
    16621 ccaaaaagga gaagctgcac agacaaaatt gattcgggta gtcactggag cagttttaga
    16681 tgtagtagtg gatatccgca aaggtagccc gacttatggt caatgggacg gatttatctt
    16741 atctgaacat aatcatcgac agttgcttgt acctaaagga tatgcccatg gattcgttac
    16801 tttgacacca aatgtgaact tcctttataa gtgtgataat tactataatg cagaagcaga
    16861 tgggggcatc gcatttgatg atccagattt agcgattgat tggccaattg atccatcaag
    16921 agcgattatg tcggaaaaag atcaccgtca tccgacatta aaagaatttg aagcagaaaa
    16981 tccatttgtt tacggagaaa tctaagaatt aaggagaaat tttcttatga aaaacatcat
    17041 tgttaccgga ggtgccggat tcatcggctc taatttcgtt cattacgtgg taaacaatca
    17101 tccagaagtg catgtcactg ttttggataa actgacttat gcaggaaaca aagagaactt
    17161 ggctggactt cctagcgatc gcgtagaatt ggtcgtagga gatgttgcag atgcagaatt
    17221 agtggaccgt ctagtaaaag aagcggacgc agttgttcat tacgcggcag aatcccataa
    17281 cgataattca ttaaaagatc ctttcccatt tgtacaaacg aatatcattg gtacgtatac
    17341 acttttagaa gcttgccgca agtatgatgt acgctatcat cacgtatcta ctgacgaggt
    17401 ttacggcgat cttccattac gtgaagacct gccaggacat ggggaaggcg aaggagaaaa
    17461 attcactgcg gaaacaccat ataatccttc aagtccatat tcttctacaa aagctggttc
    17521 agatctgtta gtaaaagcat gggtgcgttc ttttggctta cgtgcaacca tttcaaactg
    17581 ttcaaacaac tatggtcctt atcagcatat tgaaaaattt attcctcgcc aagtaacgaa
    17641 tatcttaagc ggtattcgtc caaaattata tggcgaagga aagaatgttc gtgactggat
    17701 ccatacgaat gatcattctt cagcagtgtg gctgattttg acgaaaggca gaattggcga
    17761 aacctatctg atcggtgcag acggtgaaga agataataag accgtgatgg aattgatctt
    17821 agaaatgatg ggtcaaccaa aagatgcgta cgaccatgta aacgaccgtg caggacacga
    17881 cttgcgttat gcaatcgatt cgacaaaatt acgggaagag ttaggatgga agcctgagtt
    17941 tacgaacttc cgtgatgggt tggctgacac gatcaaatgg tacgaagaac atgaagactg
    18001 gtggaaaaaa gaaaaagagg ccgttgaagc agcatatgcc aaaaatggac aataatacag
    18061 agaaaatgtc actgtattaa tggaaaaaca catgtgaggc aggcgctcgc ctgtctcttt
    18121 tttaaaataa aaatcaagga gcggataatc atatgttttt attaactgga ggaaatgggc
    18181 aactaggtac agaattgcgc catttattag atgaaaaaaa tctgcaatat gtttcaacag
    18241 atgcaaaaga cttggatatc acagatgccg agaaaacaat ggcttacatc acagaattaa
    18301 aacctgatgt tattttccat tgtgcagctt acacagcagt agataaagca gaagaagaag
    18361 caaaagaatt agatgagaag atcaatgttg atggtacaag aaatgtagca cttgcagcaa
    18421 aagctgtgaa tgctcaattc gtctatatca gtacagacta tgttttcgat ggaaaaaaca
    18481 aaaatgtaga atacgaagta gacgaccaaa cgaatccact aaatgaatat ggtcgtacga
    18541 aattattagg cgaaaaagca gtagaagaga ttttagaaga ctattatatc atacgaactt
    18601 cttgggtttt cgggatctat ggacacaatt tcgtcttcac gatgcaacgc ctagcggaaa
    18661 cccgcgacaa actgactgta gtaaatgacc agtttgggcg accaacttgg acacgtactt
    18721 tggcagaatt tatggtatat gtcatcgaag aaaaagcacc atttggtatt tatcatttgt
    18781 cgaacgaaaa tagctgttct tggtatgaat tcgcaaaaga aatattgaaa gatacagatg
    18841 tagaagttgc acctgttacg tcagaagaat ttccgcaaaa agcaacacgt ccgcagtatt
    18901 cagtcatgag cctgaaaaag acagaagagt taggatttgt cataccaact tggcaagaag
    18961 cacttgcgca aatgctggaa gctgccaaaa aaatgaataa gtaatttcct tttatcaaat
    19021 agaatttgga gcatgatatg gaaaaacaaa caagaagtgc acgacgaaaa gaaaagccaa
    19081 aagcgaacca ggcagattcg aatttggtgc ttgacctgtt tctaaaactc cgctatctta
    19141 ttggcgtttt agtcatcgtg gtcatcgtta cttttaattt aaacggaagt tcacttggtg
    19201 tttgggataa atatgtgtcg caaagagacg atgggaaaaa aactgatgtg atttttggac
    19261 agaatcggga agtgcggtca gacgaatggc tggtgcagac acctttttac ctctcacaag
    19321 ctgaagagga ctttccgttg gtgaacgagg attattcatt aaacggacaa aacatgatca
    19381 ttgcgtataa ttctcctgta aaggatatta cggttatcgg aaaaccattc aactggggat
    19441 tctttttcct cggaagagat cgaggacttt ccttttattg ggcgatgaaa ttagtcgtca
    19501 tggtcttgct tggattcgaa gtactgatga tattaacgaa gagaaaaaaa gctctatcgc
    19561 taatcggtgc atttgcgctg acattttctc cagcagtcca gtggtggttc atgcaacatg
    19621 tgggcgattt gattttcttt actttgggac tgatgactgc tttttatcat tatttctaca
    19681 atcatgataa aaaatggcta cgaacgttga tgatgctttt ggtggttatt ttcggtattg
    19741 ggtttatttt agtgatttac ccagcccatc aagtgatgct ggcgtacttg ctgatttttt
    19801 attttgttgg cctgcttatt tactatagca agaaagtttc atgggatctg ttggatgtag
    19861 tgttgattgg aggggcagtt ttatttattg gcggagtcat ggttcatttc tggctaacgt
    19921 caaaagacgc attgttagct tctttgaata ccttatatcc aggaaaacgg gtaagtactg
    19981 gaggaaagtg gacgattggc gaattttttt ctttccttac aaattggaaa attccttttg
    20041 aagatatcaa ctattcgaat aactctgaag tggccctgtt ctatcacttt tttccaactg
    20101 tattcctagc aagtccattt gtgttatttg gcaaaaaaga tagcgaacaa aagttactgg
    20161 gacgtatttt gatgattttt tgtctgtttt ctatcttttg gattaccgtt gggttgccaa
    20221 aatggctagc agaaatcact ctgctgtctt atgttcctcc attaagagcc atccttactt
    20281 ttagttttgc ggcttgttta ttatcgatct ggtttatcgc ttatatttgg agagaagatg
    20341 ttattcctat ttggtataaa ttcattttgt tggcagtaaa tgcatggtct tatttctatg
    20401 cgattacgca ttcgaaaatg gataattatt tttcggattt tgaaaccatc gcagttgctg
    20461 tgttgggaac agtgatttta gcttttgcat tatttggctg gagacgcttg ttttacctcg
    20521 cttttgccgc cttagttatc gtatctggct ttttcgtcaa tccagtcgta gaaggtacag
    20581 gagcgatttt tgaaaaaaca ctggcaaaag aaatccaaaa aatcgatcaa caagatcctg
    20641 gtaaagtttg gttgtctgaa gatgaattat ataacttcac cccaacattg ggagtgaaat
    20701 ccttcaatac agtacgcttt tatccagata tagctgcatg gaagaaaatc gatccgaaag
    20761 aagaatacga gaagtattat aatcggtatg ctcatacaag agcttttatc gctaaggaag
    20821 atacaaagtt cattttagat cgtccagata tgttttcggt cacgttgaat tttgaagacg
    20881 cagaaaaatt agggatcgac tatgtgatca gtaaacgacc attaactgat tacaaccaat
    20941 tatatgaagc gcagttcacg cagctatatg gaccggataa agacggttat atgattttta
    21001 aagtagaata tccggattat ccagatgtac cacaaacaca aactcaggaa aatcagctag
    21061 tcgtacagta ataggctagc tgagaataat cctgaaatgt tagtagaaag gagagtggag
    21121 ataattcaag caatcgtaca aaaatttgtc aacaaaatga gtgtcggttt cttgcttttg
    21181 ttactgacgc tagtcttttt tgtttggaca gcagggttag gttttccagc aactttgttt
    21241 atatataaca atagttcatt acttatcgct tttagtgtgg ctattttgct cattttaaat
    21301 gtttataaag caaaaggcgt cgattttctt tatctaggtg ttgcgcttgc ccttttcatt
    21361 ttcttttctt actttcggga attaagaaat gagtctttat ttggagactt actgtttcct
    21421 ttgattattt tattttgttt agtaattaaa tggatcgagt ggacaaaatg ggatcgcggt
    21481 atttatctga ttgtcttttc ggtcttcctc ggaatcacgt tatatcgtgt atttacagag
    21541 atccaagtac cagaaggaca aagcatctgg gctccaggca attcgctttc tgatatttgg
    21601 atcaatacga atataatcgg aagttctttg atgactcttg ctttattgat cagtggattt
    21661 gccagttctt ttgaacgatg gtatgtacga atcatcggtg cagtagcagt tgttgcagct
    21721 tttctcggga tttgggtctg ccaatctaga ggtgcattag tcgcgttgat tgtttttgcg
    21781 atattggatc ttttacctaa atcgttgatg cgtgtcattc gtgcgccatt tattgcttac
    21841 acggttacga ttcttttagc tttgccgatt tcttatctgg cggctgtctc tgaaaaagtc
    21901 aatttgttta ccggtcgaga agatatttgg cataaattct atcagacgct aggagaaaaa
    21961 tctgaacaaa ttttactagg aatgaaaaca tttatcttcc aacgaggaaa ccaattttta
    22021 ggaaaccaca atagttataa ttctattttg aatatctatg gattgatagg atttgggatt
    22081 gctgctttgc tgcttatcct ttttattggt cgcttaacgt tgaaagcaga tttatccaac
    22141 gggcagatga cttttatctg ggcctttttt gcggtgatga tgcagtcatt tatggaggat
    22201 acattgactt catacccatg ggttccgatt atttatatcc tgttggctat ggccgttcat
    22261 cgatatgatg aaccagaagt tgcggaggaa ttctatgtta tggaagaggc atatgacgat
    22321 atgacttatg atgatacatc ttatgaggaa caaccagata gcgctcattc ttccaggatc
    22381 caacgctatc attgataggc acaaaatacg agagaggctg tgacaaccgt cgcagccttt
//
LOCUS       DAFENC010000043        22423 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.045, whole genome shotgun sequence.
ACCESSION   DAFENC010000043
VERSION     DAFENC010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22423
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.045"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            6..305
                     /locus_tag="LP493_002133"
     CDS             6..305
                     /locus_tag="LP493_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2134276.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="LP493_002134"
     CDS             378..1739
                     /locus_tag="LP493_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBL2134277.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="LP493_002135"
     CDS             1761..2021
                     /locus_tag="LP493_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134278.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="LP493_002136"
     CDS             2035..2787
                     /locus_tag="LP493_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBL2134279.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="LP493_002137"
     CDS             complement(2881..3486)
                     /locus_tag="LP493_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL2134280.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="LP493_002138"
     CDS             complement(3539..4513)
                     /locus_tag="LP493_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HBL2134281.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5610)
                     /locus_tag="LP493_002139"
     CDS             complement(4891..5610)
                     /locus_tag="LP493_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2134282.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="LP493_002140"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="LP493_002140"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBL2134283.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="LP493_002141"
     CDS             7161..8558
                     /locus_tag="LP493_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL2134284.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="LP493_002142"
     CDS             8639..9079
                     /locus_tag="LP493_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBL2134285.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="LP493_002143"
     CDS             9227..9553
                     /locus_tag="LP493_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBL2134286.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="LP493_002144"
     CDS             9554..10303
                     /locus_tag="LP493_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134287.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="LP493_002145"
     CDS             complement(10383..10838)
                     /locus_tag="LP493_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBL2134288.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="LP493_002146"
     CDS             complement(11265..11540)
                     /locus_tag="LP493_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134289.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="LP493_002147"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="LP493_002147"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HBL2134290.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(12978..14429)
                     /gene="cls"
                     /locus_tag="LP493_002148"
     CDS             complement(12978..14429)
                     /gene="cls"
                     /locus_tag="LP493_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBL2134291.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            14770..17436
                     /locus_tag="LP493_002149"
     CDS             14770..17436
                     /locus_tag="LP493_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBL2134292.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            17800..18552
                     /locus_tag="LP493_002150"
     CDS             17800..18552
                     /locus_tag="LP493_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL2134293.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(18574..19728)
                     /locus_tag="LP493_002151"
     CDS             complement(18574..19728)
                     /locus_tag="LP493_002151"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HBL2134294.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYSLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            19913..22354
                     /locus_tag="LP493_002152"
     CDS             19913..22354
                     /locus_tag="LP493_002152"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HBL2134295.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
BASE COUNT         7198 a         3933 c         4673 g         6619 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaag
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag ttgccctgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg
    12721 tttttaactt ggttggactt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    12781 aggtcgtgag cctgccgtcc agctccgagt cacaaggaac aagttcaaaa aacagcttct
    12841 catgtttgtt gaatattgtg acttgtgacc gaggagttgg caggagaaca ccgtttgttc
    12901 ggaagaaggg actgtgacaa gatttttgtc acagtccctt taatcttagt atatttttct
    12961 ctacttgaat aaaaaaatta taggattgga gaaaataatc gagaaatttg ttgcttgaat
    13021 aatagccagt tagacatttc cttgactgtt tcagttgtca tggatgaaca atgtgtctca
    13081 tcttctttga actgagtagc aagttcttct aaaaactcag gatcgtaaat gacagcactt
    13141 gtttcaaaat tcaatcggta gctacgaata tcttgatttg ctgaacctac catgcagatt
    13201 tcatcatcca ttatcaatgt ttttgcatgg aggaagccgt tctcatagac aaggatttgt
    13261 acattttcct tgatcagctg ccgagcataa tattgtgttg ctcgataaat aaaaggatga
    13321 tccggtttgt tgggaatcat gattttcaca tctacaccag aggcagttgc gatttttaaa
    13381 gcagcaatga cactttcatc aggaacaagg taaggtgtct gtatccaaac acgtttttta
    13441 gcagaagtaa tcaatttgat aaatgaaagc ttgatttgtt ccctttcgtt attcggtccg
    13501 cttgaaacaa gctggatgga tgtatcagca agcttagatt catctcgatc tgctttttta
    13561 aagaaataat tcaaatgata gccgaccttt ttttcttcag gtaccgagac gttccagtct
    13621 gttaagaagc gaagctggag caaagaagaa gcggcaccga aaatccgtat atgcgtatcg
    13681 cgccaatagc cgaatttttt tgttgtattt acatattgat tggcaatatt gaaaccaccg
    13741 gtataactaa tctttccatc gatcacaacg atttttcggt gatcatggta attcaatcgg
    13801 aaacgaagta atgccctttg tgaggtaaca aatgtatgga catgtccacc atttttgatt
    13861 agacgattga aatcttttgc ttttgtgcca tgagagccaa atgcatcata taatattcga
    13921 acttccacgc cttctgcggc tttttcttct aaaacatgta agacttgctg gccgatatta
    13981 tctgtcacaa atgcgtaata ttcgatatgg atcgaatgtt tggctttttt tagatcttga
    14041 agcagtgaat ccaatttctc ttgtccgtct gtgagaagag tgacagaatt cattcttgtc
    14101 agcggcatac gatttaatga agagaagaag tcaacaaatt gctgtttgtc tttatcgccc
    14161 atgtcaggat cgtaatgttc aatggtatct cctctaaaag actgaaagtt ttctaattct
    14221 ttcaagtcac tttgtcggag atagaatttt ttcttatccg ttaatccacg tccgaaaaat
    14281 aaatataata caaagcccac cccaggaagg gcaaacaata ctaagagcca tgcccaaatg
    14341 gctgctacat ctcggggttt gatcaaaata gccaccaaag caataagtgc atttaataga
    14401 taaagggcgg ttataatact agataccaca aaaatgttcc tccttacata caataacatt
    14461 agtatagcat gatagaagaa agaagcctac caaggtgaat atacttttca ctcctttcat
    14521 gaaaatgtag gtaaatcggg ctaaagtagt tgctttttgt aggttaataa ggtaggatat
    14581 tagtacagtt gaatatctcc ttaggggagt aaccggcaac gtttgttgcg ataatatcaa
    14641 cagtaagtta accaaatggt tttctggtat tgtatgaaat ggtgagacct aagacaaatg
    14701 cgtatttgtc ttaggtctct tttttttcag acaggactag ggccaagatc aaaaaatggg
    14761 ggatgaaatt tggaaaacaa ggaacaagca caacaagcgg tctataaaga aacgatcgac
    14821 tcgttgatgc agcaaacgca gagctcaacc gatggattga gcaccacgca agcgaaggaa
    14881 aaattagaaa gagatggctt gaaccagcta aaagaaaagc cgaagaagcc aacttggaaa
    14941 ttgttcttag aaactttcaa agatgcaatg gttatcgtat tgctgattgt cgcactgatt
    15001 cagatggtca tgggtgacta catcgaattc ttagttattt ttgcagtatt gatgttgaat
    15061 tctataatca gtgttgtcca aacaaaaaaa gcagaaggtt ctttagaagc gttgaaaaac
    15121 ctttcagcgc ccgatgctcg agtgattcgt gatggtaagg aaaaaacgat tccggcaaac
    15181 gaacttgtgg taggagatat cgtgttgtta gacgcaggcg attatgtacc tgctgatgga
    15241 cgtttactag atgcgggatc attaaaagta gatgaaggta tgctgacagg agagtcgact
    15301 tctgcagaaa aagaagtaac ggatatcaca agtacggtac caatcggaga tcgtacaaat
    15361 atggtattca gtggaacgat cgtaacttac ggacgcggta aattcttagt gacttcaact
    15421 gggaataata cggagatcgg acaagttgct ggccttttgg aatcaacaac tgagcaagtc
    15481 actccgttac aacgaggtct ggataaattc agtaaaaaac taagtttggc tattttggca
    15541 ttgtctttat tgattttagg tatccaactg tttcgtattt atcttggaga aggtacagga
    15601 gatatgactg cagatatcgt cagcgcagtg atgtttgccg tagccgtagc cgtagctgct
    15661 attccagaag cattacagtc tatcgtaaca atcgtgttat ctttgggaac gaataaaatg
    15721 gcaaaacgtc atgccattat tcggaagctt ccagcagttg aaacacttgg ttcgacaagt
    15781 atcatctgta cagataagac tggtacattg acacaaaaca aaatgacagt tgttgactac
    15841 tttttaggta atggcgatac tggggatttc acaaatgacc cttcaaaatg gacagctgac
    15901 gaacgtcgct tgatcgaaat cagtgtttta gcgaatgatg catcgatcag tgaagacggt
    15961 actaaattgg gcgaccctac ggaagtagcg tttatcgact ttagtgaaaa attaaaccag
    16021 ccttatcagg aaatccgaaa caactaccca agacaagcag aacttccttt tgactcagat
    16081 cgaaaattaa tgtctactgg acacacaatt gataacaaaa attacttgtt tgttaaaggc
    16141 ggaccagata tcgtcttcca acgcagtaaa aaagtattgc taaatggtga agtcgttccg
    16201 atgacggatg aattgatgaa aaaattccaa gagcaaaatg aagctttttc aacacgcgca
    16261 ttacgtgtac tagcttttgc ttaccgtcca cttgataatt ttgatttatc atttgaagat
    16321 gaagacgatt tgatccttgt tggtttgctt gctatgatcg atcctccacg tgctgaagtg
    16381 actcaggcgg taacagaagc aagaagtgca ggaatcaaaa caatcatgat tactggtgac
    16441 cacaaaacaa cagctgttgc tatcgcaaaa caaatcggga tttttgaaga aggaaacctg
    16501 gctttgaccg ggacggaact agatgaattg acagaagatc aactaaacga agttttagaa
    16561 aaagtcactg tttatgcacg tgtttcacct gagaataaaa ttcgtatcgt tcgtgcttgg
    16621 caaaataaag gtcatatctc agctatgaca ggtgatggtg taaatgacgc accagcattg
    16681 aaacaagcag acatcggaat tgctatggga acgggtacag atgtggcaaa agatgcagca
    16741 gcgatggtat tgacggatga taactttgct tctattgtca gcgcagtaga agtaggacgt
    16801 aatgtgtttg ataatatcaa gaaagctatt tcttatctat ttgcaggaaa tttaggtgcg
    16861 atcattgcga tcatctttgc cttagttgct gactggtcca atccatttac agcattacaa
    16921 ctgttgttca tcaatttagt caatgattca ctgccagcaa ttgcattagg tacagaaaaa
    16981 gctgaacctg ctacgatgaa ccgcccgcca agagatccaa attcaggaat ctttacggac
    17041 aaaacattga tttctgtaac gtatcgtggt gtgctgattg ggattgctgt tatctttgct
    17101 caatggcttg gcatgcagca ttcacctgaa ttcggtgtag ccatgtcatt ttcaacattg
    17161 atttggtgtc ggacattgca aacattccca gcacgttcaa acacacaaac agctatccaa
    17221 gcagggttct tctctaacag aagtgtctta ctagctgtag ttgtatgtag cgcgctttac
    17281 tgcttaacaa tgatcccagg actgaaagaa gtcttctcta tcccatcagc atttggattg
    17341 acagaagtct ttacatgtat gggaatcgca cttgtgacaa ttgttttgat ggaaatcact
    17401 aaattgatca ttgtacgagt acaaggaaat aaataaaacg aatcaacgag gttgtgagcc
    17461 tgccgtttaa ttctgagtca caaggtgcaa tttcaacaaa cagcttctca tgtttgttga
    17521 atattgtgac ttgtgaccga agagttggca ggagaacacc gtttaaggaa gaagttgtaa
    17581 aatcagcatt ttgagctaat actgagggtc atctgattgg acactgttta ttcggaaaga
    17641 gggactttga cacgactttg gtcacagtcc ctttttttat ttatgataga cggaaagcca
    17701 atcattttat tattcatcaa aagagataga atagataaaa gaggagaatg atttattccg
    17761 aaaagtgaaa acatataaca aaaaattaga ggaaatcaaa tgaatgaaaa agaatgggat
    17821 gaatttgctg aagaatatta tgaaatccag caagaatcgc aagtaactat tgctgaagat
    17881 gtaaaaaatt atctgaaaac ggagaaagtc ctgcctgctg aaacagcagc agacgttgct
    17941 ggaggatctg gcagatttct ttccttagca aaagaaatta atcgctatga tttgatcgat
    18001 ttttcttcag gaatgctaga aaatgcaaaa aaagaagcag aaaaaaatga gttgccaaat
    18061 gtttccttta tcaaacagtc gttagaagaa tttatccaat caaatgagac atatgaaatg
    18121 gtttttacag cagcaaatcc agcattggta catcttattc aattagaaaa attgatgaaa
    18181 aagtcaagca aatggtgcgt gataatcaga gtagtggaat caatcgatga tgttttttat
    18241 cctatcgaaa agcaactagg aatgatagaa gaagatccta atacatcgcc agttgtaatg
    18301 gatcaatttg aaacatactt aattgatgaa ggattcaaag tgaagaaaaa agattttact
    18361 tattttacac aggaatcaat tactgaagaa ttgatgaagc tatactatga cgcgtacgca
    18421 aaagatcctg ttgtgaccag gtacattcgc aaactattca gtgaaaaacg agaaatcctt
    18481 agtacgacta agctgaccta tagactgctc ctttggtccg cagataaaaa aagaaccttt
    18541 cacgactcgt gaagggttct ttttatgatt ttattatatt ttgtagtaac gaatatcatt
    18601 ttcgatcttt gtaatcgaaa aaggtacatc tgaagtatat tctgcacatt ctccgtgttc
    18661 aggaagcgtc tcactgaaaa tcgtttcata ttcgtcaaca gtgatccgtg ttcgagaatc
    18721 tagcatctct tgatgagatt gtgcgaagag atattcttga tagttttctt ccagataacc
    18781 tgtaaaaaat tcacttactg caccagaacc gtagctgaat agaccgatgc gatctcctgg
    18841 ctgtagtgat ttcgaatttt ccagtagaga agttagcccc aggtataatg aaccagtgta
    18901 aagattaccg attcgtcggc tgtaacggat gctttcttca tagcgagcca taagacgttc
    18961 ctgattttct tcgtctgttt ggtctaatac gctttgcaat gccttttttc ccatcttagt
    19021 atacggaata tggaaagcaa tcgcctgata atcttcgagt cctcgacccg acaattcttt
    19081 atgtcgattc caaacttttt ggaatgattc gatatacgta gaattagata aaggaccatc
    19141 aacaacagga aattcgctat aatctggacg ccagaaatca tagatatctt ctgtcagaaa
    19201 tacgctgtcg tcttcaatcg ataaaatacg cgggttttga gtgatcatca tcgcaacagc
    19261 accgacacct tgcgtcactt caccaccgct tgccaagctg taacgagcaa tatcacttgc
    19321 tatgactagt acttttcgtt ctggatgatt tttgacatat tctttcgcca tgtgcaaagc
    19381 tgcggtgcca ccgtagcaag cctcttttac ttcaaaagaa cgagcaaaag attggatttt
    19441 cagtaaatgg tggataatta ccgcactcgc ttttgaatga tcaatcccgg attctgttcc
    19501 gacgatgacc atgtcgatta gctcacggtc tttttctgtt acgattttgc tggcagcatt
    19561 tgctcctagt gtaatgatgt cttcatttgc acgattgact gccatttggt cttgaccaat
    19621 ccctatatgg tattttgcag gatcatcccc acggctttct gccaactctg tcatatctaa
    19681 atataaatta ggaataaaaa aggaaagacg atcaatccct attttcattt caacacctct
    19741 ttacttatga taaaaaactt actttactaa ggtatcataa aaagattaaa agaaatataa
    19801 aaaagagaat atttaaggat tgttaaaatt taatcttaga aaaaaataac tggaacaaga
    19861 gctatttgtt tttacagcaa agaatggtat atttttgtag gaggtggctt acttgaaaga
    19921 agtcgttatg atagatgctg caagaacgcc gataggaaag tatcgcggaa gtttaagtcc
    19981 atttactgca gttgaattag gcacacttgt gactaaagga ttattagata aaacaaaact
    20041 gaaaaaagat aaaatcgatc aagtaatatt tggaaatgtc ctgcaagctg gtaatggtca
    20101 aaatgttgcc agacagattg ctttgaacag cggtctccct gtagatgtcc cagcaatgac
    20161 gatcaatgaa gtttgcggat ctggtatgaa agcagtgatc ttagcacgcc agctgatcca
    20221 attaggtgaa gcagaacttg tgatagccgg cggaacagag agtatgtctc aagcacctat
    20281 gctgaaacag tatcagtcag aaacaaatga atatggtgaa ccaatttcca gtatggtcaa
    20341 cgacggattg actgacgcat tttcaaatgc acatatggga ttaaccgcag agaatgttgc
    20401 aacacaattt tctgtgagca gagaagagca ggatcgctat gccttgtcgt cccagttgaa
    20461 agcagcacat gctgtcgaag ccggtgtatt ttctgaggag atcatcccag tcaagatttc
    20521 tgatgaagac gtgttatctg aggatgaagc agttcgtgga aatagtacat tggaaaaact
    20581 gggcacgtta cgtacagtat tctcagaaga aggaactgta acagcaggaa atgcttcccc
    20641 gttgaatgac ggtgcctctg tggtgatcct tgcatccaaa gaatacgcag aaaataataa
    20701 tctgccttat ttagcaacca tcaaagaagt agcggaggtc ggtattgacc caagtatcat
    20761 gggaatcgct ccaatcaaag ccattcaaaa attgacagat agatcaggaa tgaatttatc
    20821 aacaatcgat ctttttgaga tcaatgaagc atttgcagct tcttctatcg tagttagcca
    20881 agaactgcag ttagatgaag aaaaggtcaa tatatatgga ggagcaatcg cattaggcca
    20941 tccaattggt gcaagcggtg cacgtatctt gactacatta gcttacggat tgcttcgtga
    21001 acagaagaga tacggtattg cttcattatg tattggtgga ggtttaggct tggcagtctt
    21061 gttagaagcg aatatggagc aaacacataa ggatgtgcaa aaaaaaaagt tttatcagct
    21121 tacgccatct gaacggcgca gtcaattaat agaaaaaaat gtattgacac aagaaactgc
    21181 gttgattttt caggaacaaa cactttctga agagctctcc gatcacatga tcgaaaacca
    21241 agtgagtgaa gtggaaatcc caatggggat cgcgcagaat tttcaaatca atggcaagaa
    21301 aaaatggatt ccgatggcaa cagaggaacc atctgtcatt gcagctgcaa gtaatggtgc
    21361 aaaaatctgt ggaaatatct gcgcagaaac acctcagcgg ctgatgcgag ggcaaatcgt
    21421 tctatcagga aaatcggagt atcaagcagt gatcaatgca gttaatcatc gaaaagaaga
    21481 gctgattctt tgtgcaaatg aaagttatcc ttcaatcgtg aaacgcgggg gcggtgttca
    21541 agatatctct actcgggaat tcatggggag tttccatgca tacttatcta ttgatttttt
    21601 agtggatgta aaagatgcaa tgggcgctaa catgatcaac tcgattcttg agagtgtggc
    21661 aaacaagtta cgggagtggt tccctgaaga agagattcta ttcagtattt taagtaattt
    21721 tgctacagaa tcattggctt ctgcctgttg tgaaatccca ttcgaacgct tagggagaaa
    21781 caaagaaatc ggtgaacaaa ttgccaaaaa aatccaacag gcaggggaat atgcgaagct
    21841 tgacccttac cgtgcagcaa cgcacaacaa agggatcatg aatggtatag aagctgtagt
    21901 ggcagctaca ggaaatgata cacgtgcggt tagcgcttcg atccacgcct acgcggcaag
    21961 aaatggatta taccaaggat taacagactg gcagatcaaa ggggataaac tagttggaaa
    22021 actaacggtg cctttggctg ttgccacagt aggcggagct tccaatatcc tgccaaaagc
    22081 aaaagcatct ttagctatgt tagatattga ttcagccaag gaactagcac aagtaattgc
    22141 tgcagtaggg ttagctcaaa acctggctgc tttgcgtgca ttagttacag aaggaatcca
    22201 aaaaggccac atgggacttc aagctcgttc attagcgatc tcaattgggg ctattggtga
    22261 ggaaatcgag caagttgcga aaaaattacg tgaagcagaa aagatgaacc agcagacagc
    22321 tatacaaata ttggaaaaaa tccgggaaaa ataaaaaagc aatatcttta gaagaataaa
    22381 gcaagattta cagttatttt atttactgca gatcttgctt ttt
//
LOCUS       DAFENC010000044        20942 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.046, whole genome shotgun sequence.
ACCESSION   DAFENC010000044
VERSION     DAFENC010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20942)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20942)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20942
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.046"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            168..362
                     /locus_tag="LP493_002153"
     CDS             168..362
                     /locus_tag="LP493_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134296.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            631..930
                     /locus_tag="LP493_002154"
     CDS             631..930
                     /locus_tag="LP493_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134297.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(1027..1461)
                     /locus_tag="LP493_002155"
     CDS             complement(1027..1461)
                     /locus_tag="LP493_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2134298.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1693..2403)
                     /locus_tag="LP493_002156"
     CDS             complement(1693..2403)
                     /locus_tag="LP493_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBL2134299.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2393..3253)
                     /locus_tag="LP493_002157"
     CDS             complement(2393..3253)
                     /locus_tag="LP493_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HBL2134300.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3258..3896)
                     /locus_tag="LP493_002158"
     CDS             complement(3258..3896)
                     /locus_tag="LP493_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HBL2134301.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3911..4210)
                     /locus_tag="LP493_002159"
     CDS             complement(3911..4210)
                     /locus_tag="LP493_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2134302.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4253..5737)
                     /locus_tag="LP493_002160"
     CDS             complement(4253..5737)
                     /locus_tag="LP493_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBL2134303.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5757..6218)
                     /locus_tag="LP493_002161"
     CDS             complement(5757..6218)
                     /locus_tag="LP493_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL2134304.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="LP493_002162"
     CDS             complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="LP493_002162"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HBL2134305.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7521..8291
                     /locus_tag="LP493_002163"
     CDS             7521..8291
                     /locus_tag="LP493_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBL2134306.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8564..9391)
                     /locus_tag="LP493_002164"
     CDS             complement(8564..9391)
                     /locus_tag="LP493_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2134307.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9959..11194
                     /locus_tag="LP493_002165"
     CDS             9959..11194
                     /locus_tag="LP493_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBL2134308.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12193..12453)
                     /locus_tag="LP493_002166"
     CDS             complement(12193..12453)
                     /locus_tag="LP493_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBL2134309.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12480..13781)
                     /locus_tag="LP493_002167"
     CDS             complement(12480..13781)
                     /locus_tag="LP493_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2134310.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14073..14531)
                     /locus_tag="LP493_002168"
     CDS             complement(14073..14531)
                     /locus_tag="LP493_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL2134311.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14544..15875)
                     /locus_tag="LP493_002169"
     CDS             complement(14544..15875)
                     /locus_tag="LP493_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HBL2134312.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15886..17328)
                     /locus_tag="LP493_002170"
     CDS             complement(15886..17328)
                     /locus_tag="LP493_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL2134313.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(17315..18079)
                     /locus_tag="LP493_002171"
     CDS             complement(17315..18079)
                     /locus_tag="LP493_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HBL2134314.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(18183..19058)
                     /locus_tag="LP493_002172"
     CDS             complement(18183..19058)
                     /locus_tag="LP493_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL2134315.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(19313..19397)
                     /locus_tag="LP493_002173"
     tRNA            complement(19313..19397)
                     /locus_tag="LP493_002173"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19361..19363),aa:Leu,seq:caa)
     gene            complement(19415..19486)
                     /locus_tag="LP493_002174"
     tRNA            complement(19415..19486)
                     /locus_tag="LP493_002174"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19452..19454),aa:Gln,seq:ttg)
     gene            complement(19496..19568)
                     /locus_tag="LP493_002175"
     tRNA            complement(19496..19568)
                     /locus_tag="LP493_002175"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19533..19535),aa:His,seq:gtg)
     gene            complement(19630..19714)
                     /locus_tag="LP493_002176"
     tRNA            complement(19630..19714)
                     /locus_tag="LP493_002176"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19678..19680),aa:Leu,seq:caa)
     gene            complement(19735..19805)
                     /locus_tag="LP493_002177"
     tRNA            complement(19735..19805)
                     /locus_tag="LP493_002177"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19771..19773),aa:Cys,seq:gca)
     gene            complement(19851..19922)
                     /locus_tag="LP493_002178"
     tRNA            complement(19851..19922)
                     /locus_tag="LP493_002178"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19888..19890),aa:Gln,seq:ttg)
     gene            complement(19934..20006)
                     /locus_tag="LP493_002179"
     tRNA            complement(19934..20006)
                     /locus_tag="LP493_002179"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19971..19973),aa:His,seq:gtg)
     gene            complement(20009..20082)
                     /locus_tag="LP493_002180"
     tRNA            complement(20009..20082)
                     /locus_tag="LP493_002180"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20048..20050),aa:Trp,seq:cca)
     gene            complement(20089..20169)
                     /locus_tag="LP493_002181"
     tRNA            complement(20089..20169)
                     /locus_tag="LP493_002181"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20133..20135),aa:Tyr,seq:gta)
     gene            complement(20171..20246)
                     /locus_tag="LP493_002182"
     tRNA            complement(20171..20246)
                     /locus_tag="LP493_002182"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20211..20213),aa:Phe,seq:gaa)
     gene            complement(20282..20354)
                     /locus_tag="LP493_002183"
     tRNA            complement(20282..20354)
                     /locus_tag="LP493_002183"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20319..20321),aa:Asp,seq:gtc)
     gene            complement(20364..20436)
                     /locus_tag="LP493_002184"
     tRNA            complement(20364..20436)
                     /locus_tag="LP493_002184"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20401..20403),aa:Val,seq:tac)
     gene            complement(20452..20523)
                     /locus_tag="LP493_002185"
     tRNA            complement(20452..20523)
                     /locus_tag="LP493_002185"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20488..20490),aa:Glu,seq:ttc)
     gene            complement(20538..20627)
                     /locus_tag="LP493_002186"
     tRNA            complement(20538..20627)
                     /locus_tag="LP493_002186"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20591..20593),aa:Ser,seq:gga)
     gene            complement(20667..20740)
                     /locus_tag="LP493_002187"
     tRNA            complement(20667..20740)
                     /locus_tag="LP493_002187"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20704..20706),aa:Asn,seq:gtt)
     gene            complement(20750..20865)
                     /gene="rrf"
                     /locus_tag="LP493_002188"
     rRNA            complement(20750..20865)
                     /gene="rrf"
                     /locus_tag="LP493_002188"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         6603 a         4390 c         3331 g         6618 t
ORIGIN      
        1 taagaacaat agccttttat tatatatatt attcaaatta gttatatcga gtgaaaaaaa
       61 ctttcaaatt gattcttttt atttatcata aagatataga tacataatca ttttcactta
      121 catatatttg aatattaact aaaaacagca agaaagaaga ggatcaaatg tattatgtag
      181 aagtaaaaac aaaaggcgtc aaaaacaaac aatatgtgaa aggtatcagt aacgaatatc
      241 ctttacttgg ttcatggaaa gaagctgctc ctttttccaa accatgtgcc ataaaaataa
      301 agaacgagct agaaaaagaa ctgacttgtg gtaaagctgt tgtagatatc atcgaaaagt
      361 aaatccaatg tatagaaagg aagatcacac atgaaaagcg acgtacaaat tgctaagatt
      421 atagaattag aagaagaaga cgcagtgttg acaattgaaa aaaaataaat gtttgtatac
      481 catatgatta tttcaatatg tatcctggaa ttggagatct cgtagagcta tatcaagatg
      541 aatcaaatat acttgtcatt catcatgaaa tatagagact tataaaattg tttattttta
      601 taatgtatca gtatagaaag gaaataaaac atggattata ctgttgaatt tgacagtgaa
      661 ctacttaagc aatttccaca agaagaacat ttcatgtata aagaagcaat ttcccacaaa
      721 gtgacagagt atttggagca taattttttt cgtataaagc cagtgcgtac tcgttcggca
      781 aaaggaatat acgagatgaa agtcaaaatt aataaaaaaa attatcgcat agcatttgct
      841 ttaaaaaaaa atcatgtgtt cattttttat attagttcga atttgcaaaa aattgtattt
      901 gataaagagg tgagtaaaaa aataaaatag ctgagcattg gaggatagat tgagtgatac
      961 taagtctatc ctcttgtttt tctaaagaac taagctagaa ttttttcttt tgtacgttat
     1021 tatatgttat ttgtcattac caaaaagcac cttttttctt ctagtatcta tgacataaga
     1081 aataccaccc atttccttta cttgaacaaa tcctactgat tcataaaatt tttttgtttt
     1141 ctcagtatca tctgtcaata attcgatttg gactggtcca taactagtga tcttctccaa
     1201 agcttcattc aaaagcactt tgcctattcc ttggcgctga tacctcggat gaatgaggat
     1261 atcttgaata aatgcgatcg tcgcaaaatc agtgatccaa cgaacgattc cgataatctt
     1321 cccttcccca ttacgcttta tcagagattc agattgttca aatgctctag ctaaccttgc
     1381 agtgtctttt gtgtaattcg tccaaccaac gctcttatat aattcagaaa tctcatcgat
     1441 cataagggaa tcaatattca tttttttctt cctttcttat acaattctcc ctctaataat
     1501 acagttcttt gactatttaa tctatcacat ataactctcc tgtaaagatt ctctcgattc
     1561 cttaaaattc ctctttcctt ttagaatgca tactttttga taaataaaaa ggttgtgata
     1621 aattttcttc acaacctctg tttctctcta tcaagtgtta tcttttaatt ttctaccctt
     1681 accctagcat ctctattgcc cgtagtatgc atactttcca tgtttgcgaa aataatgttt
     1741 atctagtaaa tattgcggga tttcacatat attggggttg atcagctcgt tttctttggc
     1801 catcagacaa atttcatcta agatcaaact gttttctact gctttcatag gtgaatcccc
     1861 ccatgtgaac ggtccatgtc catagacaag tactccaggg acttcgtttg gatctaattt
     1921 tctttcctta aacgtctcga caatcacatt ccctgtatga acttcgtaag cttctcttac
     1981 ttcttctttc gttaattggc gtgtacaagg aaccttacca taaaaagcat cagcatgagt
     2041 cgtgccataa gctggcaaat cgcgtcctgc ttgcgcccac atgacggagt gcgtggaatg
     2101 agtatgagta atagcagtta tatcttcaaa agtttgatac aaaacaacat gtgtggggag
     2161 atctgaagat ggttttaagc tatcttcttc tattatattt cccgacaaat ctgttaccac
     2221 catttgatct gcttgcatgc attcatatct gacaccgctt ggcttaatga cgatgactcc
     2281 tagctcacgg tccacttcac tcacattgcc ccaagtcaat ttgactaatc cgtatcgcgg
     2341 caatgccaga tttgcttcaa ggacacgttg cttcattgct gcaatttttt cttcacaaga
     2401 catcatagcc agcctccttc aatttagaac ttaagtagtc ttttgcctgc tggatttctc
     2461 ttcgaaagtc ttggcttttt tcactccaca tttcaatcag aaatgttcca tcataatcta
     2521 gacgtttcaa atgtcttaat aatccaagaa aatcaacaca accgctacca aaaggaacat
     2581 cacgaaactg gcctgaatat tcttttgtta cagggtaagt atcttttaag tggatagcag
     2641 tgatataatc gatccctttc tcaagttctc gagccggatt attttccggc catgcggaca
     2701 aattgcctag gtctggatat acttgtagaa aaggtgaatg aatctgttct ttgatttcta
     2761 aaaattttga aatggagttc ataaatggat catccatgat ttccacggaa agaatgatgc
     2821 catatttaga agcttccttt acgctttctt ttattccttc gataaagtct tctctggaat
     2881 tcattgattt ctcttcataa taaacatcgt atccagctat ttggattact ttgacgctta
     2941 gattatgcgc caaatggatt gcttttttca ttagttgttt cgctgctttt ttcttttctg
     3001 gatcagcaga accaaacgga aatcgccgat gcgcacttaa acaaatcgaa tggatacgta
     3061 caccggagct gaacatctct tctctcagct cagctatctt ttcttcagac caatctaatc
     3121 gtgctaaccg ctcatccgtc tcatcaatcg acatctcgat aaaatcgaag tccatttctt
     3181 ttacaaggga aaaacgttct ttccatgaaa tatctttggg taacgctttt tcataaatcc
     3241 caatttgagc catttcctta cccccagata cgaatgatct catctttgaa gttttgtgcg
     3301 gccttcatcg gatcatttgc tgctgtaata ccacgaccag tgataaaggt atacacatcg
     3361 atcccttcaa ataagtgtaa tgtgtgtgga tttaatccac cagttacaga aacattaaag
     3421 cctagttcaa tcagtttttt gatcttcgat aaatcttttt caccccaagt ttcaccagat
     3481 aacagcgcat cacggctttg atggtagatt acctgccgga taccgatgtt atgccaatcc
     3541 atggcttgtt caaaagtcca attgccgtag agttctactt gcaattcacc tatttctttt
     3601 tgtgctgcct ccatagttgg aatcgttgca caacaaatga ctgtcatcca gtctgctcct
     3661 gcttttgcaa cattactcgc cactgttcct ccagcgtctg cacatttcgt atcagcgact
     3721 agttttttat ctgggaacat actgcgaata cagcgaatcg ctttttgtcc ttcctgtaag
     3781 caaagaattg tgcccacttc aataatatct actacatcac caactttcat aacatctcct
     3841 aatgcatgtt ctaagtcatt gtgatctaac gcaatttgca aattcggcct gctcatctta
     3901 gttccttcct ttacttgttt ttttggtacc actttgtttc agcaaatttt tcactgattt
     3961 ctttgactga catcacattt ttgataccga taactgtaac tccttttttc tctgcctgag
     4021 taaacatatt caaaaaattg actggcgtaa aaactacatc gtattggcca gctgaacttt
     4081 ttccctctga aatggcacaa tgatggattt tggtaattgg tacgtttagt tctttcattg
     4141 ctttttccac acttctcatc atcatcaagc ttgttcctga tccatttgca cacgatacta
     4201 aaattctcat cttaatccct ccattatgag tgttgtctaa tcagattttc ttttatactc
     4261 tctgcttttc tgcatatgtg tcatagtctt ctacaatcaa aaaataacca tcaggatttt
     4321 tccgatattg taactgcgga atagccaata aaccaatgac aactacggca attccagcat
     4381 aacctaggac tttcatgatt actgtaaaca atggccaagc tgttgcccag tcgaacatcc
     4441 cgatataacc accgtatgtt gacatcccaa tccatgtagc gaataatgct gaaccgccta
     4501 cttgtatgat tcctgaaaga aacgggaaca ggcaagcggc tttgaatcca cctcggttat
     4561 tggcataaac tgctataacg gcattatcaa agaacaacgg aatgaaaccg gctatgacga
     4621 tcgttggtga tttcaataaa atcagtaaac caatcatcaa aaactgtccc aaagcaccaa
     4681 acaagaaccc aatcgttacc gcatttggcg aaccaaagcc aaaagtagca gctacgtcaa
     4741 ttcctggaac agctcctggt aaaatcgtgt ttgagattcc ttggaaagat tgagttagtt
     4801 catcgacgaa tgtccgaaca cctaattgca agatcgccag atataccgca aaatttaaag
     4861 aagtcgtcat aatgtagaat aagaaactct gcccttcttg catgaattgc gcttgaatca
     4921 aataatcttt gcctagtaca atcagaatga tcccaaagaa aaatagcatg agtaacgaag
     4981 tagcaaccat attctcattg aaaatcgaca agaatcctgg taatttgata tcttcaattt
     5041 ttttgtcttg cttgattgat ctatttttct tttcatcccg ctttttcatc cactcagcta
     5101 attttgcaaa tataaagatt ccgaacattt gctgatgtgc cactgcaaat ccggcacctt
     5161 ctgtcaattc ctgcgtgatt cctactgtta agttagaagc tactgtccaa taacaaccta
     5221 aaatcagtcc cataaaaatc aatgcttgta tcctacctag atcaggaaag caaaacagta
     5281 aaatccaaaa agcggtagct gcttgttgaa cctgaacgtt tccggtagtg aaaacggaac
     5341 gcagtttcgt atatttctga aaacggacta ataagatatt taaaacaaat gcaatcagta
     5401 ataaaatcat cacatctcca aaggtacggc caaatgtctc cattaatcca gcatccacag
     5461 cattttgtcc aaaataagga tctgtaacca tggcatccaa attgaaccgt tcctttagtc
     5521 caaccaagat tggccgaaaa ttattgacca aaccaccaga gccaacagtc aaaataaagt
     5581 aaccgaccgt tgcctttaag aatccagcga tgcattcatg aagcgggcgt ttcagcaaaa
     5641 tatagcctaa taacacgata aaaccaatca ggtatgctgg ctgcgtcaag atatttgttg
     5701 caaaatacgt ccaaatgctt aacaaaaatt cccccatctt ttttctcctc tatcaattaa
     5761 ttatattctg ccatcacaac ttggtaatca tcgatggagt tcgtagagat gagacgctca
     5821 accaatccat ctgtcattaa taattcggat aatttttgga tattttctag atgttcttct
     5881 ggatcttttg ctgcgagtgt aaaaaacaaa ctagccgttt tctcctcatt ctccccttca
     5941 ctttcaaaac ggattggctg tttcaacttg gtaaatgaaa tagctgttcc aaaaacacca
     6001 tcactttttt ctgaagaatg cggcattgct acttgaggtg cgatcacaat ataaggaccg
     6061 tatttttcta cacaatggat gatctcctcc acatacgttt catcaataat ttccttatcg
     6121 atcaatacaa gacagctttc ggcgatagct tcacgccaat ccgtgatttc tttatctggg
     6181 taatgaatca attgatggtc aaaaaagtat ttcagcaaga aactcccctt ctttcttata
     6241 aaaacgacgg aaacggtgta tcattttcaa tcgagaagac atcttcaaat cctcgataaa
     6301 aattaaactc aagatcatct ttgtttgtcg gatagatgaa tttcccgcct acttgccaga
     6361 tataaggttt aaatccatac ttcaggcgat cctttttgaa tttccaaatt tcagtgatct
     6421 cttttggatc agccataaaa ttagaccaaa tatcgtagtg gacaggaatc actacttttg
     6481 cattcaatga ctccgccatg cgcagcatat caacagaagt aactttgtct gttatccctc
     6541 gtgggttttc accataggcc cctaaacaga catcgatttt gtgttcatta ccatgtttgg
     6601 caaataaatt ggagtaatgt gaatctcctg catgataaag attccctcct gatgtttcga
     6661 ataaatagtt tactgcaatt tgatccatct cctgaggcat ttttcctttt aatacctctt
     6721 ctggatcttc acaagtgacc aacgctgtcc gatcaaacgc ttctaaagct actacattga
     6781 tgtctttgat tttgactgca tcacctggct ttactgtaat cgttttttct tcaggaattc
     6841 cccatttttg ccacgtgcga accacttctt ttggcccaat gaatgttgct tcaggacaat
     6901 tttgatgaac tgctgcggct gtatggatat ctagatgatc ggaatggata tgtgtaacga
     6961 ttaaagcgtc tacatttttt atcgcaaaag gatcgattac gaaaggctga gtacgtaaat
     7021 taggctgcat attttgaacg ccactcatac gcatcatctg atggcctttt ttcatcatgc
     7081 cattcccatg actacgtttt cccgtcccac accatagatc acataaaata ttcgttcctt
     7141 catgactttt cagccaaatt cccgtacagc ccagccacca catagcaaaa gttccaggat
     7201 ccactacttc tgtttcgatt tcttcattca agtatgtgcc ccactcagga aatgtttcta
     7261 ctaaccactt ttcttttgtt acttcattga cagttttact catttgcttg ctccccccat
     7321 atcgttgttc caacttacaa gtaaatatta atgtgtatca gcatccatga aaaccctttt
     7381 atatgaccgt ttgtttttta tatgattttc tttcagtaat caatgattgt ttcagtataa
     7441 taaagacaga tatgaatgtt taaatgaaca actagtcaaa taaatccatg gatcaagatg
     7501 tccctcagga ggcaaaagtc atgaaaaact cacttgtcaa tattgaaaaa cgtcaaaaag
     7561 aaattttgga actgcttcag cagactgaac aactatcaac tttcgaatta gctgaatccc
     7621 ttgatgtatc tattagtacg atacgaagag atttaaattt attagaagaa aaaaacgaga
     7681 tcatacgcaa ttacggttat tgttcttata attacaaaaa ccagactgat tttgatcaat
     7741 ctggtcctga aaggattaaa caagcgattg ccagagaagc tagtaaatac attaacgatt
     7801 atgatacgct gtttatcaat tctagctcga ctgcgttgaa aacactggat tttcttcaat
     7861 ctaaccattt gacagtcatt acaaacaacg tgaaaatcaa ttactctccg cacaaagata
     7921 attgtagtta tattttaact ggtggagaga tgcgctttcc aaaagaagca ctagtgggcg
     7981 acatcgcatt aaatacgatt tcttcagtca atgcagacat ttgtatcatt ggctgtagcg
     8041 gagtcgatgt agtacatggg gtcacaacaa agatattaaa tgaatcaacg atcaacgaaa
     8101 tgatggtcaa caagacaatc aaatgtaaga ttttagtcgc tgatcatcga aaaatcggac
     8161 tgacatcaaa gttcaagatt gctgatattt cagtctttga ttatttgatc actgataaat
     8221 tttgttctga aaaagtatta gaggagatca gaaatacggg gataaaaacc attcaagtag
     8281 attcatttta agaaccagga cgtaaatatg taaataggat tatcaaaaaa atgaataaca
     8341 aatttatcga taaatgaaaa acacgctacg ctcaaattga taaaggaatc ccaagatgta
     8401 tccatccaat cgataccatc ataatctatt gcttctttta taaccgttat atgttgccta
     8461 aataggaatc aaacaatatc gaaaaaagga ggtatgacaa aagtcacacc tccttttttc
     8521 gaataaacgg tattcaaatc agaacactga tttcacaacc actttatttc aggtcgtttt
     8581 caatcacctt taccgcgtaa tcatttccgt tgaaacgcgc tatttttttt gcgtccatat
     8641 atctttctaa ataatcatct tctcctaatt gcttatggca agaagcaatt tcataaagca
     8701 agtattccaa tgcataagtc gatttatgtt tcttattata ctcaataccc ttctcacata
     8761 attggattgc tttatcataa tcctcgattt tacggtaata ggtggcgata tcataatata
     8821 caatgcagac catcagatta tcaaaatcag tctcactcaa tattttaagt gtacgctcca
     8881 cataaacttt cgcaaaatct aattctcctt ttgacaagta gatcattgcc acgtttgcag
     8941 ctgcttgtaa gtgatggata tctgtttcgg tcgtttgttc caacacttga ttaaaataaa
     9001 ataatgctgc atctggtttt ttcgcataaa gatgatcaag cagtccttga taaaataaaa
     9061 tttgatttaa aagatcagaa ttacttactt tttcctgatc gatcgtttgt aaaattttat
     9121 aagattcttg gtattttgat acagaattca atgattgaat ctcatttatt tttttcctga
     9181 ttttgtcttc ttctgtttct actaatatat cggagatctc gacattcagc tttttgcaaa
     9241 gcgcacttaa gatattgatg cctggcgaca tattcttgtt ttcgatattg ctgacagttg
     9301 cttgttcaca aatgccttct gctaattgta cttgtgttaa cccctttttc tttcggtatt
     9361 cttttagtaa tgctccatct actttaatca aaacaatttc cttcccttta aaaaattatt
     9421 tctcctttat atcatacaca aaaaaaagtt ctaaacaacc aaaaatgttt agaacagaat
     9481 aaaaatttta attttaaaat aatattcaaa ttaaacaact ggcgtatctg ctccttgatt
     9541 tctttttgtg ttatctgaat aattatcgtt tacagttata acacatagtg aaaattgtca
     9601 tggcgagaaa gtctaagaat atttttaaac ataactattt ctttcttacg tgtgtataat
     9661 gacgacagca cacctatcaa ttaatataat tattttattt ttttatgttc tcatgtttat
     9721 ttttaatgac acaacttctc gtatttatct ggcacaacat ataaatcgat caaaaaattg
     9781 ttgcgtgttt ttttgaaaat tggagtttca acttgattac aaaatttaaa tttagaagtt
     9841 gtgaaaacag cgagagacag tttaatattc aaaatataca taggctactc gaacgctgtg
     9901 ttttttagta tactagtaag aaacgaaggg atagactcat tccaataagg aggatttcat
     9961 gaagacaatt ctttttgctc ctgcagtatt caatttagct gagacaacac gaatgattga
    10021 ggttgccaaa gctatgaaag accgttatta ctgtgtattc tttggctttt ctaaaacttt
    10081 tgctcctttg atcacagaaa gtggctttga gtatcattta ctagcgccga tccttacgaa
    10141 aaaacaagaa gaacaaatca taaaatttga ccagttgcgt acacttaaaa acccttttac
    10201 caaagaaatg gttgcctctc gtatcactag tgaacagagt ctgattgcta agtttgagcc
    10261 tcgactgatt gtgacaggtt cgaatgtgac aattttttta tcggcccgca ataaaaagat
    10321 tcctttagta tatgttaaac cctatgcttt gagtgaacct ttttttcaat cagagcatgc
    10381 gctgatgccc cacgagttac gtttcttcgg ccctttaagc aatccccttt ggcactggac
    10441 aaaaaagcgt atagtaaata cccgatggat ccccaatgcc ttcaaacacg ctgcacaaaa
    10501 agaaatgctt cctttaccaa aaacaagttt acaaatgatg gatgctgatc taaatctcat
    10561 cacaacgcct aaactatttt tggaagaaga acagctgccg gaaaattatc gaatcgttgg
    10621 tccaattttt gctaagctca gtacttcctt gcctgaagaa gtgctaactt ttatacagcg
    10681 aaagcaacaa gaaagaaaac gtattatcta tttcgcaatg ggtagttcag gcaatccgcg
    10741 tatgttacgc aaaattttgt tcttcttaca aaaacaaccg gatctagcgg ttattgcacc
    10801 tattgactat ctgcttgatg acattcaatc tgactcagaa gatcttttaa taacagaata
    10861 tctgtctagt catcttttgc atgaattcat tgatttttct tttatccacg gcggggaagg
    10921 gaccgtccaa actgcctgtg aatccggcaa accgtttatc ggtgtgggga tgcaatttga
    10981 gcaaagctgt aatattgact attgtgtaaa atacggaaac gcaatcgccc tcacaaaacc
    11041 agtgactgaa agaaaactgc agattgctct gcgcgaagtt tcttcaccca agattcgtca
    11101 gcaggcacgc acgctgcaag ccgtttttcc aataaatggt ccacaacaag caattcaaga
    11161 aatcgaaacc ttcctgagca accacccaat atagtttcaa gtagaaaaag cttttttaat
    11221 agagactcat cagtaatttc gctattcgag acccagacag tgaaaataca aaaaaagtaa
    11281 atagtggatt gaaaagttag agttacttaa attacggtgt ctaaaaaaca caaaatcatc
    11341 cttaaaataa aagatctgac gctatccaaa tgagcatagg tagcgtctgc catttattct
    11401 tagtcaaatt ctttgacacc tttctctggt tggatcatct caacgtttct tcaaaagaaa
    11461 gaccataata attaggcaaa tacattttct taaaatgtgt catatagatc tagaagcatc
    11521 gctttgtaga gatttgtgcc gctagtcccc tcaacaatta ctaaatcaaa tgtaggattt
    11581 accactttat ctttgataat caacctccct cttctgttga gacaatgatc tcgcaatccg
    11641 atgcatactc ctatataaac tgccagcaat ccccacatat tgagtagatc atgtcagaat
    11701 gttctatgtc gtcagcaacg atacactaaa agtcacgttc accatgactg attgctattc
    11761 ccagcacaat tatttctata cacgtttcat gatttgaata aacactcaca tcatacatat
    11821 taccattcat acaccatact gcagccccta ctatatggtt gtaagctccc aaatctatat
    11881 ttgacttgat cactttggta gtagatctac taattctaaa tccattgctg ataaaatttc
    11941 cattttttcc tccttctttc tgccaaaaca gttaaaacaa taataatctt tatgtaaaaa
    12001 agggctgtga caaaagcctt gtcacagtcc catattccga ataaacggtg gtcaaaagct
    12061 tgcatctgcg gtaataagtt caaccaaacg aaaaataagc caacatttca caaaaattta
    12121 agaagcaatt ttcgtaaatt tcttcttatt tcttgaagct aaccacttct gttacaacca
    12181 cttttagaac atttaaagct tcgatgtgac aaaccatcta tgctgctcga tcataaaatt
    12241 gatagcaaaa attccacaaa gtacatatgt cccccatgaa aacaaaacat tcatatgcgg
    12301 tacaatgatc tttggaagaa tcacgatcaa aaatgatgcc agtgcccaaa tccatcgatt
    12361 gatttgaata tgatatgtag ctagcatatt caatataagg tgactagccg ttaataaaaa
    12421 gataaaaaca aaaaataaaa tcagccaata cattgtttcc caccttctaa aaaccaaact
    12481 tagacagtct ggacttcgtt ttctccacga ctttgttcat ctgacagcat ctttttatca
    12541 taagctttta caaatggata atagataata aatgctatca atgtgttgat catgatcaag
    12601 ataacaacac gccagtcatt tcctgctgaa agataaccgc cgattggagc tggtaatgtc
    12661 catgttggca aaacagtaaa tctattgacc atttctaatt tgactgcaaa ataactgata
    12721 atagtcaaaa ctaaaggaac taagttgaac gggatgaaca tgtaaggatt caacatcata
    12781 ggagctccaa aaattatggg ctcattgata ttgaagatac caggaataat agaaaaacga
    12841 ccaacctctt tcaagaattt tgatttacag aagaatataa acaaaacaga taccacgatc
    12901 gttgctcctg caccaccaat tgttaccgtc cattgataaa actgttcagg agcgatatag
    12961 ggtaattggg tggcagctgt accatctgcc aatgcctttg cattctcatc caacatgatc
    13021 agccacattg gacgaacaac agcccctaca atactcatgc catggatacc aaatgaccac
    13081 aacaaatgga tcaaaaacat tggtagtaaa acaccaagca aattattccc taaaatattg
    13141 gttaaaggct cgaataacga taataaggca gcgtttacat caaagcccgc gacgcttcga
    13201 atcagccaag taattgttaa aatgactgca cctggaatca atgcctcaaa actacgggca
    13261 acagcaggtg gcacttgttc tggcattttg atagtaatat ttcgattttt aaagaaacga
    13321 tatacttcca ctgcaaaaat catagataag atccccgcaa acatcccaga tgctcccaaa
    13381 gaactcatag gtaagaccca gccaagaggt gcctcttcag gagttaaaac gtttacagga
    13441 acttgtaaca taaagaacgt tcctaaagat aatataccac ctgtcacact atctaatcca
    13501 tatgatttag ctagatccga acccataaca aaagttgcat aaatagccat caatcccatc
    13561 gtcatcctaa agggtaaaac aatcgttgcc gaataagggg caataaattc attccatcca
    13621 ggaaacggta aattgataaa gaccataaaa aatgtcccaa tcaaaatcaa tgacaatgtt
    13681 gaaacaaccc cattacgaat tgctaataaa tgacgctgtg taccaatttt tgccattggt
    13741 gggacaagtt tctcttcgac ccatttcatc agcttttcca ctaaaaccac tccttttcaa
    13801 taaaatatga accattcatt gcatgacaac gcaaagaatg ttcataacta attatataat
    13861 taagaaattt tatttcaata tattctctta aataatcaaa tttattttta agaatcctga
    13921 aaataagttt tctaaatcat aggagcaaca aaaaaattcg ataattaaca aaaatcaaaa
    13981 tgattaaatc tagtgattga aacatatcat ttcaaaaaaa ttttgtaaat tcacccataa
    14041 atatcaccct atttaacttt tttcatcgta cactaaaatt caaaacaact atctttaatc
    14101 tttacttctt ggttttgttt taataaattt ccttcaaaaa tgcctggaga aactacaatg
    14161 atcaccgtat ctttttgtgc ttgctccaac ttcttcaaat ctataatagc taacagtgtc
    14221 ccttctttta cctcctggtt actttcaacc cgtatctgaa acggacttcc ttcgagttca
    14281 actgtatcta aacccatatg gatcagtatt tttctgccag attcactttc gatcgttatg
    14341 gcatgtcggg taggaaatat attatcgatt attcctttaa ctggcgcatg gatatatcca
    14401 tcatgattcg ttatagcgta tccaactcct atcatttttg aagaaaagac ctcgtctttt
    14461 actgctgtta atggaataat ttgaccacta gctacagctt ttagaatgtt tcttgtttta
    14521 aagaaatgca ctttttatca cctctacttt aatgctggcc aatatttttt gtttactttg
    14581 atcatttcat ctagtatttt ttttgcgact ctggcatttg gtacggtttg attcaatgta
    14641 aatgcttgta aagctttttg ataagaacct tcaaagtaag catctactag taacttctct
    14701 actgcaactt gtgcctccat caatccttta tgaaaatcac tgattggttt tcttagtgta
    14761 attggctcca caccagttgc accaacatat gccggtattt caacaactgc atctgaccgt
    14821 agattcggaa tcgccccttg attaggaacg attagcataa agcgacgacg atcatcattc
    14881 aacaaggaaa tagctatatc gacgatatat tgtccatgct ccccaaaatt aaagttcaat
    14941 acttcttcca caataccgcg gcgtatttta tcagccattt ctttggtatt tttctctcgt
    15001 ccatccatga ccatattagc acgtgtatac tctttgtcag tatgctcaac gaccatatca
    15061 ggatataagt aatactctaa gtaattattc gggatattac ttggaaaatt tttcgtgatg
    15121 actgacatca tttgaaaggt tttttgccaa gttttatctc ctatattaaa atcggcgact
    15181 tgcatttctt ttgttattag tttttcaata atctctggca taatttctcg ttgcaattct
    15241 ttatcataaa tcgatgtata ccagccaaag tggtttaaac cataatacgt aacgatccaa
    15301 ttcttacgat cataaccgta attcactgca atcgtttctt caattgaaat agtcatatca
    15361 caggcattaa tcatttttac attcggatat ttacgacgaa cagcttcaga aacgatcgac
    15421 tctggatttg tataattcaa aatccatgct ttgggggcat agtcttgtat atgatcgaca
    15481 atttccaata aacctttgat tgagcgcatc ccataagcaa atcctccgag tccacacgtt
    15541 tcttgtccta ctaatccatg tttaagtgga atcttttcgt ccttttctcg catctccaat
    15601 cctccaacac gaatttgtga gaaaacaaaa tcgcatcctg taaaagcaag ctttggatca
    15661 tccgttgcac gaatgcgaat atttgaaaaa ccttttcttt tcagcataaa tttaacaatc
    15721 aagtacatat ccatatttct ttcttcatca atatcatata aacgtatttc agataatggc
    15781 aaccgttttt cattgttcaa aatggcttga acgattcctg gtgtatacgt actcccgcct
    15841 ccagctatag tgataatctg ttttttcatc atcatctttt cctttctatt cttctaataa
    15901 tttattgaat tctgccataa cataagtcac ttctaagccg atgataattt gataattttt
    15961 ttcagttggt ttaatgatcc cgcttatccc taattgcttg attcgctgtt cctcgaccat
    16021 ggtgggatcc actacctcta cccgtaggcg tgtattacaa ctatagacat ccaggatatt
    16081 ggcttttcct ccaaacgctt gtagcatttt tgttgccata tattcataat ttttacttgc
    16141 taaccctaac tctgtttctt ctaaggttac ttcattgcca aactctgcct tagcttcacg
    16201 tcctaatgtc tgaatgtttc tcttattgat caaataataa aaagtaacgt aatacaaggc
    16261 aaaaaagaaa attccgattg gaagaatcaa aatagcattg gtagcgattc gaaaattgat
    16321 gagataatca acaatacatg ctccgaatgt aaaaccaatt cgtatattga ataagtaaca
    16381 gacaatccct gctaaaccgg caaaaagtgc atggatcacg tacaacatag gagaaagaaa
    16441 catgaaacta aattcaacag gctcagtgat atttgcaata aatgaagttc ctgcaccgct
    16501 tcccatgatt cctttgacca tctctttatt ttctttataa gctgctttat agatagctag
    16561 acatatagct ggtataccaa acatcattac tacaaaaaaa actgataaaa acagtccagc
    16621 ctgaggatct ccgttgataa agcgtgtcat ctctcctctg aaaacttcct tgctaggaga
    16681 tgtatagctt cctaaatcgt aataaatata cgtattcaac acatggtgca gtccaaaggg
    16741 gatcagcaaa cgattcaaaa acataaatat ccccacacct aatgctccca tatcaacgag
    16801 cagttttgca aaattatcaa tcccaatttg gatgagcggc cagataaagc ccaaaaaaac
    16861 agctgcgatt gtttgtagaa tcatcaccat agtcaatggg aatttttcgc ccgcaaaata
    16921 agaaaaaact actggtaatt tttgttcttt aaagcgatta tacgtccatg ccgctactaa
    16981 accggaaata attccaccaa aaatccccat attcacttct gggtccataa tttctaagcc
    17041 ttttttcaag gtagcaatcg ctaaaaaacc agtaagtgca ggtattcctt tgtccttatt
    17101 tttgacaaaa ccgattgcaa ctcctatagc aaataagata tccaagtttc caaaaacggc
    17161 atttccagct gcaccaatta ctgggatgtt cagcatatcg tcagctgata aacgcatgat
    17221 caatcccgct aatggcatcg ctgcaactgg aagtagcatc gctcttccaa gcttctgcac
    17281 atttgattta acattcattt ttattcctcc tctattaaat atcctcatat gttactaact
    17341 caatcaaagg atcatttttc actttttgag caaatgctga atgaattaaa aattcgactt
    17401 ggtgggtacg aggatacaca aaacttgaac catttaacaa ttcctgatcc aaatacgctg
    17461 cgtgacacat gacttcgatc gttttatctt ctctcaatat catgagtaaa cttgccaaat
    17521 attcttccac actcgtattg atttgtcgtt ttttttcatc agtttctcct acgacatcga
    17581 aacaaggctc aaaataatcg acatgacgaa cttcatcttt tcgttcaaag ttgctccgaa
    17641 ccggcaaatc atattttttt gctaatgtaa caactacctc ctgattttca tccaaagtat
    17701 gagtatgatg atgactgtct aaatgagttg gtatgatccc cgcatgataa attttttgaa
    17761 tctgagcatt ccattcctga tacagttgat ctttgtcaat gttaaatgga tgctgataat
    17821 aagataagga tctgaactct ccgctttcga taagagtatc gacagttttg aggagtggtt
    17881 tgccacacgt caatgttaaa tggactccta cacctagcct aggcatttcc tttcttagtt
    17941 tcacagcatg ctcgaaaccc ggcatatttg ccatcaatgt agttgatgtc aaaattcctc
    18001 gctgataagc atccataatc ccataattca caccatggct atagccaaaa tcatccgaat
    18061 taaaaatcac ttttcccatt tcattctcct tcttttttct actaaaatag gcgcaaccaa
    18121 ataatcatag tccatttact atgtgtcatt tggttgcgcc tatagatagt tacgccctta
    18181 ttttaataga ttcttgctag atgaattgcc aaatagatga tttcattttc ttgaatggca
    18241 agttgaaatt gctgttcgat gatatcttta atctttagtg ctgtacaata cgctttgcta
    18301 tgtttaaatg tttcagtaaa aaaaccaata ttttctactg gcgtttcttc ctgataaatc
    18361 aagcgtttaa ccaggaattt gatatgaacc attaagcgat gataagtcag tgattcttta
    18421 tcataaacgt ttgaatagga tttttctaga tgggacaaaa tcgtggtcgt catttctact
    18481 atttttaagc tctttaaact attaggctct cctagctcag cattaatgat atgcatagtg
    18541 atgaatccta cttcatttga ccctaactcg gtttgatatc gatgattgat tcgctcgacc
    18601 acttctactg ctatatcata ttcatttgga taaaggaatc tcatttctgg caacataatt
    18661 gctgtgacat ctctatcttc tctttttcgt tgaatagcaa aataaatatg atctgtcaat
    18721 gtaatataga tatttgaatc taatggagag gagatcctag ctgttatcag ttcaatcact
    18781 tcttccgcaa aatccataaa ttcgattgga atctgcgaga ctatctcact gaatcgtttg
    18841 atcttttctt tagaatctaa tacaaataat ttgtcagcat cctcaacatc aaatggctta
    18901 ctcactttag cagaaaagcc aatccctttc cccatcgcaa ttttttctat tccatcgtca
    18961 tcgatcaata cagcattatg attcagcttt ttcatcacat acaccgttaa ttcacctcct
    19021 ctatatgata aaacaaaaca acttgcagac tccttcatac atatttttgt ctccaaacaa
    19081 tttttaaaga caaaaaacga cctaagaaag aaccctttct taggtcgtgc ctaattgaat
    19141 agtagcaccc tacataattt acaaaaatag tttaacacat aataaaagcg ttatcaatat
    19201 cttttttact cgttttatga taatacttgt atcgaattga tttggaggta attacataaa
    19261 aacaaaaaaa atatagcaac tctctataag aaagttgcta tattgataat tataccggcg
    19321 gccggggtcg aaccggcacg tcctcaacgg acactggatt ttgagtccag cgcgtctgcc
    19381 aattccgcca cgccggcaaa tttaaaaata ataactgggg tagctggatt cgaaccaacg
    19441 catgagggag tcaaagtccc ttgccttacc gcttggctat accccaagaa taaagggcga
    19501 atgatgggaa tcgaacccac gaatgccgga gccacaatcc ggtgcgttaa ccacttcgcc
    19561 acattcgcca tcataaaaga tgttatttaa tttctcaata aaaaactaag atgaagacat
    19621 cttagtcaat accggcggcc ggggtcgaac cggcacgccc tcaacgggca ctggattttg
    19681 agtccagcgc gtctgccaat tccgccacgc cggcaagttg atttattagt actaaggcgg
    19741 taaccggatt tgaaccggtg atgaaggttt tgcagacctc tgccttacca cttggctata
    19801 ccgccattat actattatca atctataaaa taaagaataa attatagaaa ctggggtagc
    19861 tggattcgaa ccaacgcatg agggagtcaa agtcccttgc cttaccgctt ggctataccc
    19921 caagaataaa aagggcgaat gatgggaatc gaacccacga atgccggagc cacaatccgg
    19981 tgcgttaacc acttcgccac attcgccatg gcaggggcag caggaattga acccacacta
    20041 acggttttgg agaccgctgt tctaccttta aactatgccc ctataaaatg gaggagagtg
    20101 gattcgaacc actgaaccct aaggaacgga tttacagtcc gtcgcgttta gccacttcgc
    20161 tactcctcca tggtggcgcg ggacagaatc gaactgccga cacacggagc ttcaatccgt
    20221 tgctctacca actgagctac cgcgccatat tttaaaatta ttaattgaat aacaagaacg
    20281 acggttccga cgggaatcga acccgcgatc tcctgcgtga caggcaggca tgttaacccc
    20341 tacaccacgg aaccagttca ttatggaggt taacgggatc gaaccgctga ccctctgctt
    20401 gtaaggcaga tgctctccca gctgagctaa acctccaaca ttcaattaaa atgacccgta
    20461 cgggattcga acccgtgtta ccgccgtgaa agggcggtgt cttaaccgct tgaccaacgg
    20521 gccaggtaaa tttgctacgg agagtaaggg attcgaaccc ttgagacagt ttggcaccat
    20581 ctacatgatt tccaatcatg ctccttcggc ctctcggaca actctccaga gtgaaagaag
    20641 ctcaatactc tttctcaaaa tgagaactcc ggcagtagga ctcgaaccta cgacatcatg
    20701 attaacagtc atgcgctact accaactgag ctatgccgga ataacatcag cgtggcgacg
    20761 tcctactctc acaaggggca acccctcact acaatcggcg ctaagaagct taacttctgt
    20821 gttcggcatg gttacaggtg tatccttctc gctatcgcca ccacactgtg gtgttatctt
    20881 ttattgagta aattttgttc actcaaaact ggatttgaag tcacataagt ttttttccga
    20941 gt
//
LOCUS       DAFENC010000045        20539 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.047, whole genome shotgun sequence.
ACCESSION   DAFENC010000045
VERSION     DAFENC010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20539
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.047"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            2..74
                     /locus_tag="LP493_002189"
     tRNA            2..74
                     /locus_tag="LP493_002189"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            78..150
                     /locus_tag="LP493_002190"
     tRNA            78..150
                     /locus_tag="LP493_002190"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:111..113,aa:Phe,seq:gaa)
     gene            155..225
                     /locus_tag="LP493_002191"
     tRNA            155..225
                     /locus_tag="LP493_002191"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:187..189,aa:Gly,seq:tcc)
     gene            238..311
                     /locus_tag="LP493_002192"
     tRNA            238..311
                     /locus_tag="LP493_002192"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:272..274,aa:Ile,seq:gat)
     gene            323..394
                     /locus_tag="LP493_002193"
     tRNA            323..394
                     /locus_tag="LP493_002193"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:356..358,aa:Glu,seq:ttc)
     regulatory      583..662
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            660..1853
                     /locus_tag="LP493_002194"
     CDS             660..1853
                     /locus_tag="LP493_002194"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBL2134316.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            1983..3455
                     /locus_tag="LP493_002195"
     CDS             1983..3455
                     /locus_tag="LP493_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2134317.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            3538..4326
                     /locus_tag="LP493_002196"
     CDS             3538..4326
                     /locus_tag="LP493_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HBL2134318.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(4393..5061)
                     /locus_tag="LP493_002197"
     CDS             complement(4393..5061)
                     /locus_tag="LP493_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HBL2134319.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            5176..6888
                     /locus_tag="LP493_002198"
     CDS             5176..6888
                     /locus_tag="LP493_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2134320.1"
                     /translation="MKLILRHAKKYKVSVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            6891..8663
                     /locus_tag="LP493_002199"
     CDS             6891..8663
                     /locus_tag="LP493_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2134321.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
     gene            complement(8745..9866)
                     /locus_tag="LP493_002200"
     CDS             complement(8745..9866)
                     /locus_tag="LP493_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL2134322.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQDMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNGVS
                     LARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGELI
                     SLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKLIK
                     NNKDKYIFISKNGNPISIQAYNQSLRAVSKELNLDKKVSSHMLRHSHISLLTELGIPL
                     KAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
     gene            complement(9938..11218)
                     /locus_tag="LP493_002201"
     CDS             complement(9938..11218)
                     /locus_tag="LP493_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HBL2134323.1"
                     /translation="MLLLIGLILLIIGITKLSKANTIKKEAYELEQKNDEKLNKLHDR
                     ERFILSKEETLSDLNKQITMLKNDIILLKKEKEDLNDEINQKYDETLKNVYSSLIVSN
                     IEETSSSEIKNKLSLLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGL
                     LNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITE
                     EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKEL
                     YANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEP
                     MDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLD
                     EIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            complement(11309..11761)
                     /locus_tag="LP493_002202"
     CDS             complement(11309..11761)
                     /locus_tag="LP493_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBL2134324.1"
                     /translation="MHLNKYWILEEIEKLFVEFGSDAINPYKIIKYSDIDLIETDLGN
                     KTLGQTIHNKRCYVILINQNLSPSMKRFVLWHEIAHVRLHKGICTAAFRANNLSCMIY
                     GIEAEANMFAIEMLTRTIDEQDLSDMSQFQIIEYLGLPHNLEHLVLQH"
     gene            complement(11774..12184)
                     /locus_tag="LP493_002203"
     CDS             complement(11774..12184)
                     /locus_tag="LP493_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2134325.1"
                     /translation="MLLDRIKILLKERSMTLAELERKLNFGNGSMSRWNKSTPSGDKI
                     QKVADYFNVSTDYLLGRTDKRHYYDLTEKDKQDIALQAEKLLEGLNSDAETNYYGEPL
                     DDEDKEKLYDAIQLALALTKVKAKKKFTPKKYRQ"
     gene            12459..12671
                     /locus_tag="LP493_002204"
     CDS             12459..12671
                     /locus_tag="LP493_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2134326.1"
                     /translation="MTLKQQVLIALVKKGWSQRELARRMGISITYLRDIFIEKRKPKE
                     RLKQIEELLDIKLEVDSNDQPSEQEA"
     gene            12674..12886
                     /locus_tag="LP493_002205"
     CDS             12674..12886
                     /locus_tag="LP493_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134327.1"
                     /translation="MVQRLSKAEFKEKYKYSESTYQRRMKEFKKSRFSEGYNAVTSKE
                     ITIDVDLYEQFRTWRSKNRFRVRAVC"
     gene            13026..13181
                     /locus_tag="LP493_002206"
     CDS             13026..13181
                     /locus_tag="LP493_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134328.1"
                     /translation="MKEESKIGILNENNYTRLIIETEEGKKVAEVTLTDATPADGYRI
                     RLTPKYD"
     gene            complement(13178..13402)
                     /locus_tag="LP493_002207"
     CDS             complement(13178..13402)
                     /locus_tag="LP493_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBL2134329.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            13480..13668
                     /locus_tag="LP493_002208"
     CDS             13480..13668
                     /locus_tag="LP493_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134330.1"
                     /translation="MAYTLQQEHQILGLIKQRRKQLQDDRAALRKADELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            13994..14329
                     /locus_tag="LP493_002209"
     CDS             13994..14329
                     /locus_tag="LP493_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134331.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            14562..15503
                     /locus_tag="LP493_002210"
     CDS             14562..15503
                     /locus_tag="LP493_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="HBL2134332.1"
                     /translation="MSKSTLEMSHQEWLEDRKKGIGGSDVGTILGLNKWKSPYQLWLE
                     KTGQVVLEESGSEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPIIDGSQATADFLKEKYADVEDVQTT
                     LPIHFDELVEQKNELKRTKKEIESAIRQVDNEIISELGKREASIGITQKNIISWKFVR
                     TRRMNSKKLAEKYPDVANDEEIYNVTESRRLTEREIK"
     gene            15505..16395
                     /locus_tag="LP493_002211"
     CDS             15505..16395
                     /locus_tag="LP493_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HBL2134333.1"
                     /translation="MATNESLKNQLAAKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            16438..17238
                     /locus_tag="LP493_002212"
     CDS             16438..17238
                     /locus_tag="LP493_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HBL2134334.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWNLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADDIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            17253..18104
                     /locus_tag="LP493_002213"
     CDS             17253..18104
                     /locus_tag="LP493_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL2134335.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGAIA"
     gene            18305..18766
                     /locus_tag="LP493_002214"
     CDS             18305..18766
                     /locus_tag="LP493_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL2134336.1"
                     /translation="MPKILDACCGSRLFWFDKNNSDVTFMDCRQQYEELSTGHVINVD
                     PDVVADFRDMPFEDDVFDMVVFDPPHLRHVGENSWLAKKYGKLDELWPEDIRQGFAEC
                     MRVLRPSGTLIFKWNEEQIPLSDVLEAIGEQPLFGNKRSKTHWLVFMKKFS"
     gene            18792..19244
                     /locus_tag="LP493_002215"
     CDS             18792..19244
                     /locus_tag="LP493_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134337.1"
                     /translation="MKIVLNKCFGGFGLSHEAKMEIFKRKNIEVFPYINNFSYDSDDE
                     YTRYTGQKLGSMDFIYYFKKDPKIDKVTGIYSEIDRLYGIADDSSFSSDSNRGDKDLV
                     AVVEKLGSEASGPYASLKVVDIPDGAEWEISDYDGVETAHYGFQTGSI"
     gene            19350..19544
                     /locus_tag="LP493_002216"
     CDS             19350..19544
                     /locus_tag="LP493_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134338.1"
                     /translation="MDASEVVNKINSLKEVFGDVEVVINAQGYDNEFFKQITDISIQQ
                     GMEDEDGNFIDEVAILVTCE"
     gene            19575..19868
                     /locus_tag="LP493_002217"
     CDS             19575..19868
                     /locus_tag="LP493_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134339.1"
                     /translation="MKLKDGFYSSGHGIGGLMLDMPTKNPKTRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVVRLVDMEVIKS"
     gene            19898..20338
                     /locus_tag="LP493_002218"
     CDS             19898..20338
                     /locus_tag="LP493_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL2134340.1"
                     /translation="MSVIPQLEGEEAIVNILENIDIKQTRKNARRLLKRYRNLERLVG
                     PVKIDFSVMTVTKNLKFTIDSQNEEIIEAISTRDSVIEALTRLSRIHFQVLYYSYCFP
                     NKMSMYQIGEKLGYSDRTIERMKAVALVEFAEAYKSGELISRTK"
     gene            20413..>20539
                     /locus_tag="LP493_002219"
     CDS             20413..>20539
                     /locus_tag="LP493_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HBL2134341.1"
                     /translation="MVLFDVKKYETPSAKDVDMERTKHNVAVFLSAYLSARCRVGQ"
BASE COUNT         6680 a         3309 c         4184 g         6366 t
ORIGIN      
        1 tggttccgtg gtgtaggggt taacatgcct gcctgtcacg caggagatcg cgggttcgat
       61 tcccgtcgga accgtttggc tcggtagctc agttggtaga gcaatggatt gaagctccat
      121 gtgtcggcag ttcgattctg tcccgcgcca ttatgcgggt gtagtttagt ggtaaaacca
      181 cagccttcca agctgttgtc gcgagttcga ttctcgtcac ccgcttttag tttttatggg
      241 cctatagctc agctggttag agcgcacgcc tgataagcgt gaggtcgatg gttcgagtcc
      301 atttaggccc atttatttta ttggcccgtt ggtcaagcgg ttaagacacc gccctttcac
      361 ggcggtaaca cgggttcgaa tcccgtacgg gtcatggaag atactttttg agtatctttt
      421 tctttttatc tgaaagaatg attttaaaaa gcttagcaga gttatcttta tggatgattg
      481 tgctaagctt ttttggacag ttctaatgta aaatattttt atatttttta agcaaaaaaa
      541 tgaaaaaata cgagcagaaa actgttttat ctgctatact tggttcgttg caagttcccg
      601 aaaggatccg caggacggag atgccttgta accgaattta actaggggga atcattataa
      661 tggtagaaag acacttattt acatcagaat ctgtttctga aggacatcca gataaaattg
      721 ctgaccaaat cagtgatgca atcttggatg caattttaaa acaagatcca acagcacgag
      781 tagcgtgtga aacgtctgta acaactggtc ttgttttagt atttggagaa atatctacga
      841 cggcatatgt agatattcaa aaagtcgtac gggaaacaat aaaagaaatt ggttatacac
      901 gtgcaaaatt cggatttgat ggagatacag cagctgtatt ggttgcgatt gatgaacaat
      961 ctcctgatat tgctcaagga gttgatgaag cacttgagat ccgggatgaa gataaaaaag
     1021 acgtattaga tgagattggt gctggtgacc aaggtttaat gtttgggttt gctgtagatg
     1081 aaacaccaga attgatgcct ttaccaatcg ctttgagtca tcgtctggta cgacgcttgg
     1141 cagatttgcg taaatcaaat gaattaacgt atttacgtcc agatgcaaaa tctcaagtaa
     1201 cggttgaata tgatgatcaa ggacaaccgg aacgcgtaga tacaatcgtt atttcaacac
     1261 agcatgatga tgcagtagat aatgaaacaa ttcgtcatga tgtcatcgaa aaagtagtga
     1321 aggaagttat tccagctgaa ttattagatg atcaaacgaa atattatatc aatccgactg
     1381 gccgatttgt cattggtggt cctcaagggg atgccggatt aacaggaaga aaaatcattg
     1441 ttgatacgta tggcggttat gctcgtcatg gtggcggtgc tttttctggt aaagatgcga
     1501 caaaagttga ccgttctgcc agctatgctg cacgttatat tgctaaaaac attgttgcag
     1561 cagggcttgc tcgcaaagca gaagtacagc tagcttatgc gattggtgtt gctcaacctg
     1621 tttcgatctc aatcaatact ttcggtactg gaacggttcc ggaagaagaa ctgattgctg
     1681 cagtgagaga aaacttcgat cttcggccag caggaatcat cgagatgctt gatttgcgtc
     1741 gtccgattta caaacaaaca gctgcttacg gtcattttgg tcgtacagat gtagatttgc
     1801 cttgggaaca tacggacaaa gtagatgcgt tgaaagcaag tttagcaaaa taagttatat
     1861 tcagctggaa cgatcgccaa gtggtggttg ttccagcttt ttttatggca gttaacctct
     1921 tgaaaaagat agtaattatt tatctatttt tagatcctgt cataatgaaa gggaggaata
     1981 agatgaaaaa agaaacaaat gttactttgg tcacagtgag tattttcatt gcaacgttca
     2041 tgacggctat tgaaggtaca atcgtaacaa ccgctatgcc aacgattgtc ggttcattac
     2101 atggaatgga aatcatgaac tgggtatttt cgatttattt gctgacaaac gctatgctta
     2161 ctccgattta cggaaaactt gcggataaag tgggacggaa accaatcttt atttttggga
     2221 cattattgtt tattatcggt tcgttatttt gcggtttatc tcaaagcatg attgggttga
     2281 ttgctgctcg tgcgattcaa gggatgggtg ctggggcaat gatgccagta gctttgacga
     2341 tcatcggcga tctttattct attgaaaagc gagcaaaagt tttaggtttg aatagttcag
     2401 cctgggggat tgccagtgtt tttggaccgc ttgcgggagg attcatcgtt gaaacgatca
     2461 gctggcactg gatctttttt atcaatgtgc cgatcggaat tctattaatt attttgattt
     2521 ggctatattt aaatgaacca aaaatcatac atgagtctaa accaatggat atttttggta
     2581 gttttagttt gatggccatg cttgtctcat tgctgttagg gttccaatta ttaggagacg
     2641 aaggaatgag tccgcttgtt tctgctttgc tgctaggtag tatcgtaatg ttaggtattt
     2701 ttgtttttgc cgaaaaaaga gctaaagatc ctgtcatcat gatgcattta ttcaaaaatc
     2761 cactatttgt tgtggtcaac ttggctgcag cattggctag tggttttttg atgggaatcg
     2821 atgtttatat ccctatgtgg atgcaaggtg tattagggct gaatgcagca attggtgggc
     2881 tggtattagc accattatca ctagtctgga tggtcggttc tttccttgca agcaagtgga
     2941 tgactcaaat gaaaactcat tgggtcttga gaattggact actaatcgca gctattgggg
     3001 gcgcttggtt gtatcttatg cctttcagaa gtaactattt atggtttttt gctatatcaa
     3061 cggtcatcgg tataggctta ggtgtgacca tgactacctc gactgtcagt gcacaaaata
     3121 gtgtatctcg tgaccagctt ggtgtagcaa cttcttttaa tacgttagtt cgaacaattg
     3181 gtcaaacagt catggtttct atttttggtt tattgataaa tggggtaact aaacgagaac
     3241 ttgcagcagc aaatttaaca aatgatgcag atatcatgaa taaactggtg aatccacaaa
     3301 cggctaaata tattgatgcg gatattttgt taccattaag aaaaattctt tatgatgggt
     3361 tacattccgt ttatctagtt ggcttgttac tcgtgatcat tgctttggtc ttaacgcttt
     3421 tcgttcatga aaaaagtggt aaaataaaac agtagtttcg gttaagatat gtacgtagcc
     3481 gaatcattca aatttaaagt tattcaaaaa taacttctta ctaaggaagg cgaaaatatg
     3541 gcatttattc aagcaaatat ttattcgaat gtgttagaaa tggaagtcaa tctaaatgtg
     3601 atactaccgc aaacaacaaa aaaggtgatt ggcaccagtt cagagcaaga gacaacggat
     3661 atacctgttt tatatttact tcatggaatg ggtggcaatc atagtgtatg ggaaagacgt
     3721 acgtcgattg aacgttatgt agcaaactac ggattagctg tcatcatgcc atctactgat
     3781 cttggctggt acacagatac agtttatgac atgaagtatt ggacattcat tgcagaagag
     3841 ctacctgaga tttgtcatga attattcccg caattaacaa gaaaaagaga aaaaacatat
     3901 gccgctggat tatcgatggg cggatatggc gcgttaaaac taggccttgc aaaatcagaa
     3961 aatttcgcag cagtaatctc tctttcaggc gctgtttctg taggaaatcg aatggatgat
     4021 cttttgatgg ttcgtaaagc atctttttgg gaagggatct ttggaccatt ggatcaaatc
     4081 gaaggttcaa aaaatgatcc gcaatactta ttgaaagaac tagtaaaaag cggaaaacca
     4141 gttccaagat tttatatggc ttgtggggaa tctgattttc tttatcaggc aaatcaggaa
     4201 atggtatctg ctatgcagga acaaggcttg gcggtcacct ttgaacaagg acctggcgat
     4261 cataactgga tcttctggga ccaatggatt caacgtgcat tggcgtggct aatggaagaa
     4321 aaataaaaaa agagtcttaa aaagatagct cctatagaga tcacaaacat agtgatctct
     4381 ataggagctt ttttactgct cgttttctct tcttttattt tgttggcata agccttcaat
     4441 ataggtttgt gcactcgtta gaaagagtgc tttttcattc aattctgcat gggactgcat
     4501 actttcttta aatccctcta attgattttc aactacataa ttacgcataa atagaactgt
     4561 ttctttcaaa aattcatttc cgtccataat tttttgtcga agctgctgtt catgctgctg
     4621 atccattaac tgtccaatca ataaattgtg gagagaggca atggcctgat gactttgggt
     4681 gactgaaaat ccttcacgaa caagtaattg gatcatttgc tccaaatgtt ctaatcgact
     4741 cggaaaagcg ggcacagtat tgatttctaa ttctgcccca caagggaaac gtgtataaag
     4801 gtcatagtaa ttttccatat actgcagcaa ctgttcattc caaggcaaag ttggatctgg
     4861 aagcgctaat tcttcttcca ttgtttcagc cattttttgc aagagctgtt gtttgttttt
     4921 gaaataccaa tataaagcag gtgcttgaac atgaattctg tttgcgatgt ttcgcatgga
     4981 aagctgcgaa agagcttgtg tttcagccag gatatcaaag gcggcctgaa tgatgattgc
     5041 ttgagaaagc tttatttcca ttttatcaac ctcgtgtatt gcattatctt tttaaacatg
     5101 gtaaattgtt agtcggtcta attttacagt gttaaattag tcctgtcaat ttaaacaaag
     5161 gggtgtaatc aacgaatgaa attaatctta cgacatgcga aaaaatataa agtatctgtt
     5221 tttatttcct tgctgtccgt agcagtcatg gttgcagcag cattatggca acctaagtta
     5281 ctacagcaag tattggaagc tattattaca gaagataatg atgaaatgaa aacaattggt
     5341 atttacctga tcagtctggc tttgctagga ttagccgcag gtgtaacgaa cacgattttc
     5401 tctgcaaaag tagctcaagg cgtaagtgca gatatccgag aagaagcatt tcgaaagatc
     5461 cagacatttt catttggaaa tatcgaacag ttctctgctg gaaatcttgt tgttcgtcta
     5521 acaaatgata tcacgcaaat ccaaaattta gtgatgattt ctttgcaatc actttttcga
     5581 attccattct tatttattgg tgccttcatt ttagctatga tcacgatgcc gcaattatgg
     5641 tggatcatcg tagcgcttat cgttacggta tttctgatta cggcactttc atttacaagg
     5701 atgggcaagc acttcatgat cattcaaaaa ctgattgatc gtgtgaatag cattgcaaaa
     5761 gaaaacttac tagggattcg tgtagtgaaa tcttttgtac aagaagaaaa ccaattgaag
     5821 tcattcagca aagtaagtga ggacttaaca aaacacaaca tcatagtcgg tacattattt
     5881 tctgtgatga tcccgtcctt catgctggct gccaatttgg ctgtggttgg ggcgatcttt
     5941 tttgtgagcg atcttgttaa agatgatcct acgttaattg gtggaattgc ttcattcatg
     6001 aactacttga tgcagattat gatggcaatc attattggcg gaatgatgat gatgatgact
     6061 tcaagagcag ccgtatcgct gaagcggatt gcggaaattt tagatgctga accagatctt
     6121 acttatttag acgttccaga acaagagttg acgggttctg tcacttttga ccatgtttct
     6181 tttcgttatc ctggtgagga tacagatacg cttaaagata tcagcttttc tatcaaacct
     6241 ggagaaatgg ttggtatcgt cggggcgact ggtgccggga agtcaacact agcacaattg
     6301 atccctcgtc tatttgatcc gacagaaggc aaagttgaag taggtggtgt agatcttcgt
     6361 caagtaaatg aaaagagttt aagacaaacg gtttcctttg ttttgcaaaa agcaatttta
     6421 ttctcaggaa cgattgctca aaacttgcgc caagggaaaa agaatgcaac agaaaaagag
     6481 atggaacatg cttcttctat tgctcaagca aaagaattca tcgaaaagtt atctgatcgt
     6541 tacgaagcac caatagaaga acgtagcagt aacttttctg gtggtcaaaa gcaacgttta
     6601 tccattactc gtggcgttat cggtaatcca aagatcttga tcctagatga cagtacgagt
     6661 gcactggatg ctcgctctga aaagctggtc cgagaagcac tcgatcgaga tttgaaggga
     6721 acaacgacga ttgtcatcgc acaaaaaatt gcttctgttg tcaaagcaga ccgcatctta
     6781 gtattggatg aaggcagatt agtcggcgaa ggaacccatg aggaattggt agctggaaac
     6841 cgtgtctatc aggaaatctt tgaaactcaa aaaggaacgg aggagtaagt atgactgatc
     6901 taataaaagc aagtaaattt ttctatcact atttgaagcg gtacaaactc tcctttttct
     6961 ttatctttat cacagtgatc attgctacct atctacaagt aaaggcacct caatacatcg
     7021 gggaagcttt tcaagaatta gctaattacg taggaggctt gatgcaaggc gtagacgata
     7081 aaagcaaatt tgtttctgta atatggaaac tcttgctgtt ttatgtacta gctagtgcag
     7141 ccaactttat ctatagtatt ttgttcacac aagtagtagg gaagtcaacg aaccgaatgc
     7201 gtatcggtct attcaacaaa ttggaaaaat tgacgatccg tttctttgat tctcatcaag
     7261 acggtgaaat tttaagtcgt tttaccagtg acttagataa tattcaaaat agtttgaacc
     7321 aagctttgct tcaagtcatc acgaatgctg ttttacttgt cgggatcttg atcatgatgt
     7381 tccgccaaaa tgtagagtta gcttgggcta caattgcttc cactccagta gccgttttga
     7441 tagctgtctt gattatccgc aaagcacgga aatatgtgga tcttcagcaa gatgaagtgg
     7501 ggaaactaaa tggttatatg gatgaaaaaa tcagcggaca acgtgtcatc atcacaaatg
     7561 gcttacaaga agaaacgatt gaaggattct tagagcataa tcaaagtgtt cgcgaagcaa
     7621 ccttcaaagg acaagcttat tctggtctac tatttccgat gatgcaagga atgtcactgg
     7681 tcaatacagc gatagttatc tttttcggcg gctggttagc attaaatggt gatttggaac
     7741 gttcggtggc attaggctta gttgtgacat tcgtccagta ttcacaacaa tattaccaac
     7801 cactgatgca gatttcatct ggatacagca tgatccaatt agcgattaca ggggcaagac
     7861 gattgaatga aatatttgat gaaaaagatg aagtcaaacc agaaaacggt aaagcatttg
     7921 atggtgttga aaaaggtctt gcgttgcagc acgtagattt tggttattct ccagaaaaac
     7981 tagtcttgaa agatgtctcg atcaatgtgg acaaaggaga aatggttgct cttgttggtc
     8041 caacaggatc ggggaaaacg acgatcatga atctgctaaa ccgtttttac gatgtcaatg
     8101 atggttcagt agtcatcgat ggaatagata tccgagatta tgatcttgat gcattacgta
     8161 gacatgtagg aatcgttttg caagaatctg tattgttctc cggaacgatc aaagacaata
     8221 tcacattcgg caaaccggac gcttcagatg aagaagtcat caatgcagca aaacaagcga
     8281 atattcatga cttcatcatg acgttagaaa aaggttatga tacagagata tccgaagaaa
     8341 ataacttatt cagtacaggt caaaagcagt tgatcagtat tgctcgaacg atcatcacaa
     8401 atccatcttt attgattttg gatgaagcaa caagtaatgt agacacggta acagaagcaa
     8461 ggatccaaaa agcaatggat gaagcaatca aaggaagaac cagctttgtg attgctcacc
     8521 ggctgaaaac aatcttgaat gcagatagaa tcgttgtctt gcgtgatggg gaagtcattg
     8581 aagaaggcag tcatcatgag ttattagcag aaaatggatt ttatgcggaa ctttatcata
     8641 atcaatttgt atttgaaagt taaattaaaa gaacctcgtt ataacggggt tctttttata
     8701 tattttatgt tgtttgtttt tataaggggc agaaaagggg caatttaaat ttctattttt
     8761 cctagttttt ctactagttg attttgcata tttttagttg tatgagtata aatctttaat
     8821 gttgtttttg aatcttcatg tcctacacga tccataatgg cttttaatgg gattcctaat
     8881 tctgtaagta gagaaatgtg ggaatgcctt aacatgtgag aagaaacttt tttatctagg
     8941 tttaattctt tggatactgc tcttaaagat tgattatatg cttgaataga tatcgggtta
     9001 ccatttttag agatgaaaat gtatttatct ttattattct taattaattt gttttcttca
     9061 attaattgat ctatgatttc tttagcatta cttgataatt caatggttct ataagaacct
     9121 gtatttttag ttgttgtttt aatttttaac tcgtaatcat aagtaccaga aaccgtaatt
     9181 ttattaccat cataatcaga ttcagtcaaa gatatcaatt caccataacg tagtccagtt
     9241 aaaaacaaaa atttagtaat taaagaataa cgtgactgtt gatgtgaact tttttgttta
     9301 ctagcaatca tttgaacttc ttcttttgat aaataaccat ctttttcttt ttttatttct
     9361 tcgtttgtct taggttttct tgctaaagaa accccattta cgggattata ttttaatcca
     9421 tatcgacggt tggcgaattt aaaaatcatt cctgtaaaag tttttaaatg tattacataa
     9481 ttatatgata aatttttttc aaaatagtag taatctagca tatcttgtat aagattacta
     9541 ttaacgtttt ttacaagtac atcatctttt atatattttg aaattaatga tagataaacc
     9601 tgagttgttc gataggaact ttcttttaca gttggcttgt atttttcatc ccatttagtt
     9661 tttaattctc caaaagttag tggtaattct tcatttcgtt ttattttttc tgcgattttt
     9721 tcattcaaaa gtaagttagc ttgattccaa gcttggcgtg aattgctaga taaagtaacg
     9781 gacacttttc tctttttttc agttaaggga tccgtataac gttcggtgta cttaaatttt
     9841 ttgtcattta ttttttctaa ccacattatt tctattcctt tcgaatatac gttcctatta
     9901 attgttaaaa gaaaaagccc gaaggctttt tatatattta atcttttgac aattctaaag
     9961 atcgtctata ttgttcagct ttagctaatt ttgtaaatgt tactgttcca ttataatttt
    10021 ctaaaacaac tttctctatt tcgtctagtg aaactttgaa aaattctttt ctttgattaa
    10081 ttttattaac ttcttgtttt ctaaaatgat tatgcaattt agtttccaaa gacggagcgt
    10141 cctctgaaaa aatcatcgca tgaacgtcaa attcaaatgg aaccgatgca ctactcaatt
    10201 cttttattct atccataggt tctaatcttc tagtcatacc aattttatat atgtcttcac
    10261 caaaagaccc aatattacta attacataca cataaccggc tctagtattt aattctcttt
    10321 gtaatacatt ttcacgtata acttctaatt cttttaattt ttcttccagt tcttgaattt
    10381 tatttgcata taattctttt tccacatctg cattagcttt ttgcatatat gcgattaatt
    10441 tggaaatttc agaattgaat tgacgttgtt ctttatcaat acgtttcttt tcacgatcaa
    10501 tttctctacg aactttttcc tcttctatca tctgttcttt tattgctttt tgttgttctt
    10561 tttcttcggt aattttcact aaataagagt aatgaagttc tagttcttga agtttaaact
    10621 ctaaaagacc cttccttaat tcagcattgt cattcttgaa taaattatta attttatcaa
    10681 atatttttat gattttttcc ctagtcgagt ctatattaga aatagttagt ttattgagta
    10741 atcctttcac ttctgaatca aatggaatga gcattttttt ctttaaatta tttttctctc
    10801 gtttatttaa aataagaggg acagaaacag catcgtcaat aatatattcc ttttctttta
    10861 attttaacaa agaaagctta ttttttattt cagaagatga agtttcttct atatttgaaa
    10921 cgataagtga agaatagaca ttttttaatg tttcatcata cttttgattt atttcatcat
    10981 ttaaatcttc tttctctttt tttaataaaa taatatcatt ttttaacata gtaatttgtt
    11041 tatttaaatc tgatagtgtt tcttccttac ttaatataaa tctttctcta tcatgtaatt
    11101 tatttagttt ttcatcattt ttttgttcta attcataagc ttcttttttt attgtgttag
    11161 ctttcgacag tttagtgatt cctataatta ataaaataag tccaatcaat aataacattc
    11221 aaaactcctc atttctttga tataattatt gtagagttta ctcagaaatg aggaaagagt
    11281 ccatgtgaaa gcatgggctt ttttattttt aatgttgtaa tactaaatgt tcaagattat
    11341 gaggaagccc taaatattca ataatttgga actgactcat atcagataaa tcttgttcat
    11401 ctattgttct agttaacatt tcaattgcaa acatattagc ttcagcttct ataccataaa
    11461 tcatacaact aaggttgttt gctctaaaag ctgctgtgca aataccttta tggagtctaa
    11521 cgtgggctat ttcatgccat aatacaaatc ttttcataga aggtgatagg ttttgattaa
    11581 ttaatatcac ataacatctt ttattgtgta tcgtttgtcc taatgtttta ttccctaaat
    11641 cagtttcaat taaatctata tcagaatatt tgattatttt atatggatta atcgcatcag
    11701 atccaaactc tacaaataat ttttctattt cttctaatat ccagtatttg tttaaatgca
    11761 taccaaagcc cacctattga cgatattttt taggagtgaa ttttttcttt gctttaactt
    11821 tggttaaggc aagtgcaagt tgaatggcat cgtataattt ttccttatct tcatcgtcta
    11881 aaggttcacc ataataattt gtttcagcat ctgaattcaa gccttcaagt aatttttcag
    11941 cttgtaaagc aatatcttgt ttatcttttt ctgttaaatc ataataatgg cgtttatcag
    12001 tacgtcctaa aagataatca gttgatacat taaagtaatc tgcaactttt tgtattttat
    12061 ctccagatgg agtactttta ttccatctag acatgcttcc atttccgaaa tttaactttc
    12121 tttcaagttc tgccaacgtc attgaacgtt cttttaataa gatttttata cggtctaata
    12181 gcataggata tgcattcctt tcaaaatacc gacaaaaaaa gtatttttct gcaaattatc
    12241 tatttacaaa tagagaattt gcagttatac tagttttgta agcaagatat ttacggcata
    12301 caaagactaa aagcaataaa ctaatagtct ccccagacat cagtaagctc gctttttgtg
    12361 cgctgtattt tgtatgctta cataatagca tatttgcagt ttttgtcaaa cttattagac
    12421 aaaaatatta gaaaatattc gataaggggg tatgaagcat gactttaaaa cagcaagtat
    12481 taattgcttt agtaaagaaa ggttggagtc aaagagagtt agctcgacga atgggtatat
    12541 caattactta tttacgagat atcttcatcg aaaaaagaaa acctaaggaa cgtttaaaac
    12601 aaatcgaaga acttttggat atcaagttag aagtagattc taatgatcag ccatcagaac
    12661 aggaggcgta aaaatggtac aacgtttgag caaagcggag tttaaagaga aatataagta
    12721 ttctgaaagt acttatcaaa gaagaatgaa ggaatttaaa aaatcacgtt ttagtgaggg
    12781 gtataacgca gttacttcca aagaaataac aattgatgtc gatttatatg aacagtttag
    12841 aacatggcgt tctaaaaatc gatttagagt tagagctgtt tgttaatagc taaaaaatct
    12901 aaattcacca cttctgaaaa gaggagttgc tgctctcctt tcaagtttgc caaagtccac
    12961 gttttttcat tttggcaact cctcttcttg gaggtggtga cggcgagaga cgaaggaggg
    13021 atgacatgaa ggaagaatca aaaataggga ttttgaatga gaacaattac acaagattaa
    13081 ttattgaaac agaagaaggg aaaaaagtag cagaagttac attgaccgat gcaactcctg
    13141 ctgacggtta tcgtattcga ttaactccta aatatgatta accttttggt gggtgtggat
    13201 cgtttccgtg actatcacgg ctttgaattt ttccatctct gccatgaata aatagctcag
    13261 atccttgatt tttagaaatc tctctagcga tttttactgc ttctgatttt gtattagtat
    13321 gtgcagtcgc tttagaattt ccagcacctt tgacattcca accaccattg gaattaggta
    13381 caacatgttg attttttccc atagttttca cctccatttc tatagaaata ttttatcaaa
    13441 tagaaatgga gaaattcaat aaacgaaagg agaagtgata tggcatatac cttgcaacaa
    13501 gaacatcaaa ttctcggttt gattaaacaa cgcaggaaac aattacaaga tgaccgtgca
    13561 gcgcttagaa aagccgatga gctatcagat aggcaagctg aactaattgc ttctgaactt
    13621 gaggatttga gaatgctaga aataaaaaat agggagatta gattatgaag aagacagaca
    13681 cactttttat aggattcatt ttggggttat tagtgattgt agcgcaccaa agtattatcg
    13741 ggggaagctt gttcgcagca ttgatggttt taatcaatct gcttgattca aaagaaagga
    13801 gcaactatgg cacgagaaga agcgctaaaa atcggtaaag tgattgctga taatcggtgg
    13861 ggaaatagcc gccctattat tttaagcaag caacatatcg aaaagcaaaa agcatggcaa
    13921 caaataaaaa agtgactctg ccagccagca aagagtcaca tacaaattta taaaactagg
    13981 agaattatat cacatgaata agaaaattga aaatcttatc gaagaattga aacgtgaatg
    14041 ccaaaagcaa ggtgtttcta ttatttgtac agcccaaaaa gaaggggaac ttaaaagtct
    14101 cgtttatggt gagacaacag aaattttact ttgtcttgct atgcaagaag aacatttaga
    14161 tgaaaatctc ccattgtcag cacatattat gcgtagaatt gctgtggatg cttacgaaca
    14221 agcgaaaaat gaagaagaaa atcaaccttc aaatcatact tttgttatta ataacaagga
    14281 agatttagct gatgtgatga ctcgtattct caagggggaa tttcaatgat gaatgaaaaa
    14341 acaattgatc tactcattat tttatttttc acgttagtga ttgtagcgaa aagttatgta
    14401 atctttggct tgttattcgc aattaccatg cttgtgcttt gcgtgttagc aagcagaaaa
    14461 gaggttaaac atgaacgagt tagcaaatct tgacaactat ttaactgatc ctgattatgc
    14521 taaaccacca tatgaagcac caattgatga ggaggatgaa gatgagtaaa tctaccttag
    14581 aaatgagcca tcaagaatgg cttgaagacc gtaagaaagg catcggaggt tcggatgttg
    14641 gaacaatttt aggattgaat aaatggaaat ctccttatca actatggcta gaaaaaacag
    14701 gacaagtagt acttgaagaa tcaggaagtg agcccgctta ttggggtaat gttttagaag
    14761 aagtggttgc taaagagttt caggaacgta caggcaaaaa agtacgcaga agaaaccaag
    14821 tatttgaaca tccattacat ccatttttaa gagcaaatat tgatcgggaa gtagtgggag
    14881 aaaatgccat tctggaatgc aaaacagcca atcaatttct cggtaaagaa tgggaaggcg
    14941 aagaggtacc gcttagctat ctctgtcaag ttcaacatta catgaacgtt ctaaacaaag
    15001 actattgtta catcgctgtc ttaatcggtg gtcaaaaatt tatctggaag cggattgaac
    15061 gagatcaaga gctgatcgat acaatcactg aacaattagt agagttttgg gaaacaaacg
    15121 ttcttggagg tatcgagcca attattgatg gtagtcaagc gacagctgat ttcttgaaag
    15181 agaagtatgc agatgttgaa gacgttcaaa cgacgttacc aattcatttc gatgaactag
    15241 ttgaacagaa aaacgaactc aaacggacta agaaagaaat tgaatcagct atccgtcaag
    15301 tagacaacga gattatcagc gagctaggta aacgtgaagc cagtatcggt atcactcaaa
    15361 aaaacatcat cagttggaaa tttgtccgta cgagacgtat gaactcgaag aaactagcag
    15421 agaaatatcc agatgtcgca aatgatgaag agatttataa cgttactgaa tcaagaaggc
    15481 taaccgaaag ggagatcaaa taatatggca acaaatgaat cgttaaaaaa tcaattggca
    15541 gcaaagccac agaaacaagt tgcaccaggt caattaggac ttaaagcttt gatgaataca
    15601 ccaacaatga gaaagaagtt cgaagaggtg cttcatgaca atgctaatgc ttttatgtcg
    15661 aatgttatga ctcttgtatc taatgacagt tatcttgcag atagtgaacc gatgtctatc
    15721 atgagtggtg cgttaactgc tgcaacatta aatcttgggc tagataagaa tttaggttat
    15781 gcatatttag ttccattcaa tagtaaaaac aagcaaacag gaaaatggga aaagaaagct
    15841 caattcatgc ttggctataa aggatatatc caattagccc aacgatcagg taaatacaaa
    15901 gcattaaatg tgatcgaagt ttacgaagga gaactaaaaa gctggaaccg actgacagaa
    15961 gagtttgagt ttgatccaaa tggtagaacg tctgatgaag tcattggata tgttggctat
    16021 ttcgagttac tgaatggatt caaaaaaact gtctattgga ccaaacaaga aatcgaagct
    16081 catcggattg ctaacaataa agatcgcgat aagacaaagt taagtggtgt gtgggcatct
    16141 gattacaatg caatggcacg aaaaactgtt ttgagaaatc ttctttctaa atggggaatc
    16201 ttgtccatcg aaatgcaaga agccaccaca tcggatgaga gagtccaaag ggttcaagaa
    16261 gacggcagca ttattgctga aacagaagtt gaagaagata ttcctgaaag aaaagaagca
    16321 gaggttatat ctgaagaaaa tgaagatgta caaactggat tatttgatgc atctaatccg
    16381 ccgttaaaca aataatgagg gagctttctc ccttgctttt ctagaggaga aatacgaatg
    16441 aacacaggat atgtcaaatt acatcgaaaa gtgatgaatt cattcgtttg gaccaatcct
    16501 tatatgtata aattatggaa cttgtgtttg atgaaagcga gtcatgagaa tcgcaagata
    16561 ctttttaatg gaaaagagat acaagtgaac agcggagaat tcgtcacagg gcgcgatgct
    16621 atcacatctg agatgaacga aggcgtgaaa cgtgaacatc aagtgaacag cggttctgta
    16681 tggagatggc taaaacaatt tgaaaaaaac ggaatgttga acatcaaatc aactacgaaa
    16741 tacagcgtta tatcaataaa aaactggtct ttgtaccaaa gcagtgaaca acaaatgaac
    16801 atcaaacgca caacaagtga acaacaagtg cacacaaaca agaatgaaaa gaattataag
    16861 aatgaaaaga ataataaaac atcatcgtcg caaccacgca aaaagcgtgt ttacgacacc
    16921 gactcagttt actacattct cgcggaggag ttattcaaac agatttgtca gaatcaggaa
    16981 atcaaaaagc cgaatctgca aagttgggca gatgacattc ggaaaatgat cgagatcgac
    17041 aagcggaccg aaaaccaggt acggggaatg attgaatgga gtcagcacaa tgtgttttgg
    17101 gcatcgaata ttttatctgc taaaaaattg cgagaaaaat acgacacaat ggcagcgcaa
    17161 gcaaatcgtg attataaaac aaaacaaact aaaacgcttg aatacgagaa atttagcaca
    17221 gatgagttgc ctatttgaga ggaggcgtag gcatggaaac tgttggggaa atcatggaaa
    17281 agctgataca gaaagtgctt gtccaacgtg gcgaatgtcc tgaatgcgga cagcctttgt
    17341 atggatggcg tacgaagaac cctgatggct cagaacgttg taagccaacc tgtatgcaat
    17401 gtgggtataa agcattgcga gttcaggaag acttacaaac agaacgaatt tacaacgaga
    17461 gcctgaaagc aagagcaatc aattttttca aaggtggttc tgttgtgcct aatcaagcgt
    17521 tgtttgattg cacattgcag aattatcaaa ttgtcgatca agaaacaaga caagcggttg
    17581 aagtaaccaa acgctttgtt aattcagtct tgttaggaaa tccaagtcac cttgttttaa
    17641 ctggaaaaca aggaacaggt aaaagtcacc tagcgatggc agcggcttgg gaagtcttga
    17701 agcgatcaaa ctacgataaa aaaatcttat ttatcgggtt acaggaaatg ctggatcaaa
    17761 tcaaattttc gtacaacaat cctgaactca gaaaaacgat tgagggatcg ttgattgcag
    17821 atatcaaaac agcggattta gtcatcattg atgatatcgg ttcagaacta ggaaaagatg
    17881 catcagatag tcgagcgttt ggcataaaca cgctaaattc gttcttggat gcacgacaga
    17941 acctagcaac gattatcaca acgaacttgc ttggtgaaga actgaaaaaa gcttacggta
    18001 cgagaacaat atcaagaatg tttgtcaact ctgatggatt tacgatggta ttttctcaaa
    18061 cagcagacaa gcgcataaaa ccagtcaaag gagcgatcgc atgaatttga ctaaacaaga
    18121 aaaaagaatc tgtcgtcaga taatgttgca aattataggt gatcgtgaca tggacgaatt
    18181 atctcaacaa gagagtcgaa tggttcggaa gataagtaag ctaattattt atcgggatac
    18241 agaaagattt ctcactgttt taggtaacgt ctacgagaat ccagagttat tggaggtaga
    18301 gtaattgcca aaaatattag atgcatgttg cggtagtaga ttgttctggt ttgataagaa
    18361 caattctgac gtaacattta tggattgtcg tcagcagtat gaagaattat caacaggtca
    18421 tgtgatcaat gttgatccag atgtggtcgc agactttcgc gatatgcctt ttgaagatga
    18481 tgtgttcgat atggttgtat ttgacccgcc acacttaaga catgtcggcg aaaactcatg
    18541 gcttgccaaa aaatatggaa aattagacga actttggcca gaagacatca ggcaaggttt
    18601 tgcagagtgt atgcgagttt tacgaccttc aggaacatta atttttaagt ggaacgagga
    18661 acagatacca ctttctgatg tgttagaggc tattggagaa cagccattgt ttggtaataa
    18721 acgaagcaaa acacattggc ttgtgtttat gaaaaaattc agctaacgga ggaaacaaag
    18781 gaggaaaagt aatgaagatt gtattaaata aatgttttgg tggctttggg ttgagccatg
    18841 aagcaaaaat ggaaattttt aaaagaaaaa atattgaagt attcccatac atcaataact
    18901 ttagctatga ctcagatgat gaatacacga gatacacagg ccaaaagcta ggttcgatgg
    18961 attttatcta ctatttcaaa aaagacccga aaatcgacaa agttacagga atttatagcg
    19021 aaattgaccg actgtacgga attgctgatg attccagttt ttcaagtgat tcaaacagag
    19081 gtgataagga cctcgttgct gttgtcgaaa aactaggaag tgaggccagt ggaccatatg
    19141 caagtcttaa agtcgttgat atacccgatg gggctgagtg ggaaataagt gattatgacg
    19201 gcgttgaaac tgcacattat ggttttcaaa caggtagtat ttagtccact aatgacaact
    19261 aaagaggagg cagaaggatg agtgaagatg aatactttga acagtagtct attaacgaca
    19321 gagattttta actggaaagg ggtgtagtca tggacgcatc ggaagtagta aataaaatta
    19381 atagtctcaa agaggttttc ggagacgtcg aagtagtgat aaacgcacaa ggctatgaca
    19441 acgaattttt taagcagatt accgacatta gcattcagca aggaatggaa gacgaagacg
    19501 gaaactttat cgatgaagta gccattttag tgacttgcga gtaagtaatt gacagctaaa
    19561 gaggaggaag cggaatgaaa ctaaaagacg gattttactc cagcggccac ggcatcggcg
    19621 gtttaatgct agatatgccg acaaagaatc ctaaaacacg taagaaacca aaattcaaag
    19681 tcggtgacat ggttcgctgc gaagcagaag gattcatcta tccatttcgt ggatatgtag
    19741 aacacgtcta taatcactca gcaatcattc gcattgaaaa cacgatggaa tgtgataagt
    19801 ggttagcgaa aagcaaagag aatttagcag tggtgagatt ggtggacatg gaagttataa
    19861 aatcttaatt ttgctttttt acaactatcc tacaacaatg agcgttattc cacaactgga
    19921 aggagaagag gcaattgtga acattttaga gaatatagat attaagcaaa caaggaaaaa
    19981 tgctagacga ttactaaaaa gatacagaaa tttagaacgt ttggtcggac cagtgaaaat
    20041 agacttttcc gtgatgactg ttaccaaaaa tttgaaattc acaattgaca gtcaaaacga
    20101 agaaatcatt gaagcgataa gtactcgaga ttcggttatc gaagcattaa cacggctaag
    20161 tagaatccat ttccaggtac tttattatag ttattgtttt cctaataaga tgtcaatgta
    20221 tcaaatagga gaaaaattag gatattccga tagaactatc gagagaatga aggcagtagc
    20281 tttggttgaa tttgctgagg cgtataaatc aggagaactc atttcacgta caaaataaaa
    20341 aaagtcggat tcctccgact atgaataata tttccgacat aagtattata tcataattgg
    20401 gggaatcaga ggatggtact tttcgatgta aagaaatatg agacaccaag cgcgaaagat
    20461 gttgatatgg aacgcacaaa acataatgtc gctgtgtttc tttcagcata tctatcagct
    20521 agatgtagag tagggcaac
//
LOCUS       DAFENC010000046        20511 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.048, whole genome shotgun sequence.
ACCESSION   DAFENC010000046
VERSION     DAFENC010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20511
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.048"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..96
                     /locus_tag="LP493_002220"
     CDS             <1..96
                     /locus_tag="LP493_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HBL2134342.1"
                     /translation="QRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            843..1073
                     /locus_tag="LP493_002221"
     CDS             843..1073
                     /locus_tag="LP493_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134343.1"
                     /translation="MRNYWYVSLTNEYPRTIDDCSVRVVRSVQIKGKYSIVEMGREAE
                     PCEIDACKLVYCGHGFYDEPNIQNNINKNLRD"
     gene            1232..2065
                     /locus_tag="LP493_002222"
     CDS             1232..2065
                     /locus_tag="LP493_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small subunit of terminase"
                     /protein_id="HBL2134344.1"
                     /translation="MARQRDPRRDEAKRIWLESNGEKQLKEIASELNVSDSQVRKWKS
                     QDKWSAELISNVTNGKSNVTNQGGAPIGNQNAKGNKGNSRASPPVGNKNALKTGEYET
                     IFFDTLTDNEKDIYSSLNDDPSFALSEEIRLLKIRQLRMMKRIQQAEAGLNDEEVERL
                     QQLRKIKTPIEKNGKKLEIKREVMQDVQISRKKHRKIDDILSIEDSLTRISNQLAKAI
                     KQMNELYMNEYRTDLIKAQTDKIQAETNEIGGNNSGEEIEEWKQAVLNAANKRAVKEN
                     E"
     gene            2058..3473
                     /locus_tag="LP493_002223"
     CDS             2058..3473
                     /locus_tag="LP493_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBL2134345.1"
                     /translation="MNNEFIPFADIGSAIDYYYDKPVAFCQDILHLNPDEWQENVLND
                     LAEFSKVSVRSGQGVGKTALEAGAILWFLTCRPYAKVIATAPTMKQLYDVLWAEVAKW
                     LNDSLIKNLLKWTKTKIYMVGDSERWFATARTATKPESMQGFHEDHMLIVVDEASGVS
                     DPIMEAILGTLSGFDNKLLMCGNPNNIEGVFYDSHNSDRDKYRVHKVSSYDSKRTNKD
                     NIEMILKKYGKESDVARVRIFGEFPKGALDSFISLETVELATEKQISDSLVNKTKVAH
                     IGVDVARYGDDSTILFPRIATRALEYEKYSKRSTMETTGYVINMAKNLMSQYPSIDKV
                     MIKVDDTGVGGGVTDRLEELIEDKHYPFEVFGVNNGSTSEDDFYDNLGTQLWGNIKEM
                     LEENMTANLNGEQPVIELPSDSSLIKELSTRKFKMTSRSRIRLESKDDMKKRNIGSPD
                     IADALALAFYEPPSHYQFIQF"
     gene            3485..5014
                     /locus_tag="LP493_002224"
     CDS             3485..5014
                     /locus_tag="LP493_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBL2134346.1"
                     /translation="MISTVLSLERYKKLRVKYATQIEDGMFDPNGFIEDMKPFFADRE
                     RKYLAYTSEKNEIDNRPKPNTDIVKVNNKLHAGMYSIVVDQAVNHFTGIPIKWDYDVS
                     EQKRTLIQRLKDKFLKNDIELPTVPEAFNKLTSNLDSMRFAMLDSETATFQGACGVAF
                     RLLEPVEEDDGWKLRASNIEPWRAERYGNAGIYIKEKYDSYQKKFFQEMKVMTRNKIL
                     TYACYGDLNFVTSGTFKKIDETDNPLGTITLAEFKNNTNRYCDFEVAEEIGDAIDRAL
                     SDQQNEIEQFKLAYMLVTGTTMSKGTAKEMMNQLGIINLKAPTAKAEYVTKNLAKDFN
                     EYHMDLLKKQFYTICKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAETIAAFLKFHDKVEIEPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMMELESGSAYPDSEYNFGGGGNSDDRNEVLDQTSRTGGSSKAQTRKSD
                     T"
     gene            4932..5984
                     /locus_tag="LP493_002225"
     CDS             4932..5984
                     /locus_tag="LP493_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBL2134347.1"
                     /translation="MTIETKYWTKRRELEDQARLKQENQTLKKLTSVFPEALKEIQAK
                     LLSQADLHNITYPEMMEFYSTSNQKKYREYVEKNYKSLKMYDAKYKEFIDEFFPPFDY
                     AKVNRLLQIRSDVFKILAEYAMDADVNQYFSDRLEEILQRTYSSNANVFVQLLNVDIP
                     NYLPENEIKHYLNYPWSGKTFSRRLWGNISSLEQKLSNAIVKSVASGEGVIHALNTMR
                     LDSEICDMFKLEESKYNKAIENLVRTEYAKFAQDGIEKSYLETGIEEYNVLTAKDERV
                     CRICGGKASKNPYKLKDAVIGENRAPFHSRCRCTDVPNLPKLGKDIDEEYDRLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            5986..6303
                     /locus_tag="LP493_002226"
     CDS             5986..6303
                     /locus_tag="LP493_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134348.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYEKMGCIVVRTDYKEGK
                     SSN"
     gene            6430..7053
                     /locus_tag="LP493_002227"
     CDS             6430..7053
                     /locus_tag="LP493_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HBL2134349.1"
                     /translation="MSMKHKSLMPMNLQYFAEGDDQKFSFDDFKSFVESNEEAQKFIQ
                     SQSQSVADKQLEAWKQNNLDKIKQDTIKEYEESKKNKSPEQIQLEKLQAEFEAEKALR
                     VTSDNKAFVAEQIAGLELDGELKESISQFMLNNLVSSDTDFTKNAVEGFTSVLNAINE
                     KHADALKELQMKSAFGGTQQSNNQVQQNNETLTNPEEQLGQILQQFN"
     gene            7068..7958
                     /locus_tag="LP493_002228"
     CDS             7068..7958
                     /locus_tag="LP493_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HBL2134350.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            7981..8196
                     /locus_tag="LP493_002229"
     CDS             7981..8196
                     /locus_tag="LP493_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134351.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            8208..8549
                     /locus_tag="LP493_002230"
     CDS             8208..8549
                     /locus_tag="LP493_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134352.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            8549..8920
                     /locus_tag="LP493_002231"
     CDS             8549..8920
                     /locus_tag="LP493_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134353.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            8913..9308
                     /locus_tag="LP493_002232"
     CDS             8913..9308
                     /locus_tag="LP493_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBL2134354.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGEVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            9310..9687
                     /locus_tag="LP493_002233"
     CDS             9310..9687
                     /locus_tag="LP493_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134355.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNNPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            9688..10296
                     /locus_tag="LP493_002234"
     CDS             9688..10296
                     /locus_tag="LP493_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL2134356.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            10296..10637
                     /locus_tag="LP493_002235"
     CDS             10296..10637
                     /locus_tag="LP493_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134357.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGTVVEDAAGVMEE
                     MQTATDKQSVKKALSRAYSFIADTLFEGQFTGEDYCKGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            10879..13668
                     /locus_tag="LP493_002236"
     CDS             10879..13668
                     /locus_tag="LP493_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBL2134358.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANPFVLIIGAVVGAI
                     AVFGYFMATNEELRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVEGVK
                     DAWSGTKEWFSNTWKGIKDGATGLFDKTVETSRNAVDSVKNAWSNMKKWFSDTWQSIK
                     DSAREKWNGIKGSIMSVAGPLITGIKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LAPVLFITSMISGGWEETKNNMIAVWNNIKESAINIWESIKNIFVSYFTNIYFAALNI
                     WTGFKLTLINIWNEVVNQAKSIWLNIKYFFINLWIDIKYFAIQKWIELKFSIIQTWID
                     LKYNAITTWNNIKQFFKDTWKNIKDTAYNTWISIKNTMINTWNNIKDSFWNIVTGIVN
                     SAENAWTNLKNGVSNAINRVKEIFNSLREVNLFEIGKNIIDGLINGVKEKWNALKDTI
                     KGIAGNIKNWIKGALDIHSPSRWMRDMVGKNIVQGIIVGIDKEQSKLDQTMTNLVKTP
                     SVQPVVNGISHLPITQTKQNISASETKEIHLHLNVYGDLPDSMVRKITTKIKTELTRQ
                     MKRDAGAVGGTLYAT"
     gene            13658..14398
                     /locus_tag="LP493_002237"
     CDS             13658..14398
                     /locus_tag="LP493_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL2134359.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYKNVTRKIECYYKAPSIDMVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            14395..17157
                     /locus_tag="LP493_002238"
     CDS             14395..17157
                     /locus_tag="LP493_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL2134360.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCGIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLVEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRIIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     VLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSVGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWRIYDILCNNGFTK
                     QSACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNLF
                     NAAGIKEPITSLDAQVRLLIWTFTNGQWMGVVQPTTVDGFKACTDPRQAAYAFERNYE
                     RPAATHPERQDYAVNWYNKFKDLKPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYS
                     GYLGGCGMGAGTKYGLTHVIGNTSAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIIN
                     WARGGQVGSWFADGTYGHTGVIRGLANGRMQTYEQNTELGMICGKLDRQYYSASAISS
                     IVIPPK"
     gene            17170..18078
                     /locus_tag="LP493_002239"
     CDS             17170..18078
                     /locus_tag="LP493_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HBL2134361.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKINYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FERWRQEQEHSFQDWREGQESDYLAWFESIKDILKTIDPGGVMLAELTDARVDIQGVR
                     HASISERLLADMDYLYQKLRATLFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVAFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            18078..18698
                     /locus_tag="LP493_002240"
     CDS             18078..18698
                     /locus_tag="LP493_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134362.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVLTELPYASEEDDGIITAEMYQKILNSGEGDYVLPVATI
                     DRLGGIKVGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGTI
                     SSTGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            18702..19151
                     /locus_tag="LP493_002241"
     CDS             18702..19151
                     /locus_tag="LP493_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134363.1"
                     /translation="MTDIVKIKQSNVQVYPQTHWNAIEGKPTTVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKAKLDGLANITFEKVGTV"
     gene            19151..19645
                     /locus_tag="LP493_002242"
     CDS             19151..19645
                     /locus_tag="LP493_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134364.1"
                     /translation="MADIVQLKEDGVAKYLKTHVEAIDGKEALVQTDGDQAIAGHKNF
                     SGSVTINNKRVLTTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGN
                     DSVILTVPEGYRTPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSAYSFVI
                     TYSI"
     gene            19659..20090
                     /locus_tag="LP493_002243"
     CDS             19659..20090
                     /locus_tag="LP493_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134365.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
     gene            20092..20229
                     /locus_tag="LP493_002244"
     CDS             20092..20229
                     /locus_tag="LP493_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBL2134366.1"
                     /translation="MYSYEDIKLMYDWGCFTNEQVMVFVPLCITEEEADKIISKEESA
                     S"
     gene            20267..>20511
                     /locus_tag="LP493_002245"
     CDS             20267..>20511
                     /locus_tag="LP493_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134367.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLV"
BASE COUNT         7420 a         2829 c         4227 g         6035 t
ORIGIN      
        1 caaaggaata atactagcga agaatcggtt aaagtagaat caaacagaat tatcatccaa
       61 tttgcttcat cgttagaact ggttgctttc aagtagccag tttttacact ttttataccc
      121 ttttattacc aatttggttt ccattttata ccttttttat accaatcact tacctattca
      181 acgttgtatt atgatagtgt cgaaaaatta ggaaacagga tcgacaaaat aaaatgtaag
      241 ggaggaaatc tccctcatcg tttaattaag cttcgatagg cagcaacgga aatattaaga
      301 ataaggatgt gaatttcaac tccttctaaa ttgttcttat tatctatcat ccgttgctgt
      361 ctattgtttt tttaattatt cacacgataa ctaaaggtaa gtgaagagaa atgattccat
      421 taataatttc aatttttgcg ctttgtctta atgtatatat gattggattt aaaaatgggc
      481 aaaataaaaa atagtagcag ccaagaataa ttttatagtg tcactgtggc ggaaagggta
      541 gacgctaagc atgtgtgcta ggtcaatgct tcggcaacca tgcaaggttc gattccttgc
      601 cagtgacttt ggcaaccgag gcatcggcgg tttaaaaata taggggtgcg caatttcgta
      661 cgcgttttgt gcatcgtgta ggttgctatt acataactgg ttaggttaga ttgagatttg
      721 ggattcggta caaatgaatc gtcaaatgtc tcaagcacag gatcggaaac gtccctgcct
      781 gtgcattaca tattagatca ctctttgagt ggtctttttc tttacataaa ggaggctaca
      841 taatgagaaa ctactggtat gtatcgctaa ctaatgaata tcctcgaacc attgatgatt
      901 gttcagtgcg tgttgtgcgt tctgtacaaa tcaaagggaa gtactctatt gtcgaaatgg
      961 ggagagaagc agaaccatgt gagattgatg cgtgcaagct cgtttattgc ggtcatggtt
     1021 tctatgatga accaaacatt caaaataata ttaacaagaa tttgagggat tagaatgcaa
     1081 gaaatggctt aaaaatctcc aatcaggaca aatcaagtta gacaaagttt ccgatttaaa
     1141 gatattgatt gaagctgatt taatgctaaa agatattgaa aattagaaaa caaaactcaa
     1201 cctaaacaga atgtgaggtg gtgtgtattg aatggcaaga caacgtgatc caagacgtga
     1261 tgaagccaaa agaatttggt tagaatccaa cggagaaaag cagttaaagg aaattgcatc
     1321 tgaattaaat gtttcagatt ctcaggttag aaaatggaaa tcgcaagaca aatggagcgc
     1381 tgaattgatt agtaacgtta ccaatggcaa aagtaacgtt actaatcaag gtggcgctcc
     1441 tattggtaat caaaatgcta aaggtaacaa aggaaatagc cgagcttctc cgccagtggg
     1501 taataaaaac gctttgaaaa caggtgagta tgaaacaata ttttttgaca cgttaaccga
     1561 taatgagaag gacatctatt ctagtttgaa tgatgatcct tcttttgctt tgtccgaaga
     1621 aatacgactt cttaaaataa gacaacttcg aatgatgaaa agaatccaac aagctgaagc
     1681 tggactaaat gatgaagaag tcgaacgatt gcagcagcta agaaagatta aaactccgat
     1741 tgaaaaaaat ggtaaaaagc tagaaatcaa gcgtgaggtt atgcaagatg tgcagattag
     1801 cagaaaaaaa catcgcaaaa ttgatgatat tctttcaatt gaagattcat tgactcggat
     1861 tagcaaccag ttagctaaag ccatcaagca aatgaatgaa ctttatatga atgaatacag
     1921 aactgattta attaaagctc agactgataa gatccaagct gagacaaatg aaattggcgg
     1981 aaataattca ggtgaagaaa tagaagaatg gaaacaggca gttttaaatg ccgcaaacaa
     2041 acgggcggtg aaagaaaatg aataatgaat ttattccttt tgctgatatt ggttctgcca
     2101 ttgattatta ctatgataaa ccagtagctt tttgccaaga tattttgcat ttgaatcctg
     2161 atgaatggca agaaaatgtt ttaaatgatt tagctgaatt ttcaaaggtt tctgttcgtt
     2221 ctggtcaagg agttggaaaa acagcattag aagcaggagc aatactttgg ttcttaacgt
     2281 gtcgacccta cgctaaagta atagcaacag ctccgacaat gaagcaactt tacgatgtac
     2341 tttgggcaga ggtagctaaa tggttaaatg atagcttgat caaaaactta ctgaagtgga
     2401 caaagaccaa aatttatatg gttggtgatt cagagcgttg gtttgctacg gctagaacag
     2461 cgactaaacc agaaagtatg caaggttttc acgaggacca tatgttgatt gtggtagatg
     2521 aagcttctgg tgtgtctgat ccaattatgg aagctattct tggtacgcta tcaggttttg
     2581 ataataagct gttgatgtgt ggaaacccca ataatattga aggtgtcttt tatgattccc
     2641 ataattcaga ccgtgataaa tacagagttc ataaagtatc aagctatgat agtaaacgta
     2701 caaacaaaga caatatagaa atgattctta aaaaatatgg aaaagaaagt gatgttgctc
     2761 gtgtccgtat ttttggagaa tttccgaaag gtgcgttgga ttcatttatc agtcttgaaa
     2821 cagttgaatt ggctacagaa aaacaaatta gtgattcttt agtcaataaa acaaaggttg
     2881 ctcatattgg tgtcgacgta gctcgatatg gtgatgattc tacgattctc tttcctagaa
     2941 ttgctaccag ggcattggag tatgagaagt attcaaaacg tagcaccatg gaaacaacag
     3001 gatatgtcat caacatggcc aagaatctaa tgagtcaata tccgagtatt gataaagtga
     3061 tgattaaagt cgatgacact ggtgtcggag gtggtgtaac cgaccgccta gaagaactta
     3121 tagaagacaa acattatcct tttgaggtgt ttggagtgaa taacggttca acatcagaag
     3181 acgattttta cgataattta ggtactcaac tatggggaaa catcaaggaa atgttagaag
     3241 aaaatatgac agcaaatctt aacggagaac agcctgttat tgaattgcct tctgatagtt
     3301 cgttaatcaa agaattaagt actcgcaaat tcaaaatgac aagtagaagt cgtatacgtt
     3361 tagaaagtaa agatgatatg aaaaagcgaa atattggtag tcccgatatt gctgacgcac
     3421 tggctttagc gttttatgag ccaccaagtc actatcaatt tattcaattt taggaggtga
     3481 gcttttgatt agtacagtat tatctttaga gagatataag aagctacgtg ttaaatatgc
     3541 aacacaaatt gaagatggaa tgtttgatcc gaatggtttt atagaagata tgaaaccatt
     3601 ttttgctgat cgcgaaagaa aatatctagc ttatactagc gaaaagaatg aaatagataa
     3661 tagaccaaag cctaacactg atattgtaaa agttaataat aaacttcatg ctggtatgta
     3721 ttcaattgtc gtagaccaag cagtcaatca ttttactggt atacctatca aatgggatta
     3781 cgatgtatcg gaacaaaaaa gaacactcat tcaaagatta aaagataaat tcttaaaaaa
     3841 tgatatagaa cttccgacag ttccagaagc ttttaacaaa ttaacaagca atcttgattc
     3901 catgagattc gcaatgcttg attctgaaac tgcaactttt caaggagctt gtggagtagc
     3961 tttccgattg ctagagcctg tggaagaaga tgatggttgg aagttaagag caagtaatat
     4021 tgaaccttgg agagcagaaa gatatggaaa tgccggaatc tatatcaaag aaaagtatga
     4081 ctcttaccag aaaaaatttt ttcaagaaat gaaagttatg acaagaaata aaattctgac
     4141 atatgcttgc tatggtgatt tgaattttgt tacaagcgga acgttcaaaa aaattgatga
     4201 gaccgataac cctttgggga cgattacctt ggcagaattt aaaaataata cgaatcgtta
     4261 ttgtgatttt gaagtagctg aggaaattgg agatgcaatt gatcgtgctt tgtctgatca
     4321 acaaaacgaa atcgaacaat ttaagcttgc gtacatgctt gttactggca caacaatgag
     4381 caaaggcact gctaaagaaa tgatgaatca gctagggatt atcaacttaa aagcccctac
     4441 tgcaaaagct gaatatgtca caaaaaattt agcaaaagat ttcaatgaat atcatatgga
     4501 tctattgaaa aaacagtttt acaccatttg taaagcaatc gattttaacg atgaggtgtt
     4561 taaatcaaac agttctggag aagctcgcaa gtggcaaatc attagcctag aagcgaaaac
     4621 aaatactaaa gagcaatatt ttagagaagg attgaaagaa tgcgcagaaa caattgctgc
     4681 ttttcttaag tttcatgaca aagtagaaat tgagcctgaa aaaattattt ttactttctc
     4741 tagatctttg ccaactgatt taagttattt agctgaagct ttacctaaac ttgcaccata
     4801 cgtatccaaa cgaactattc agagccaaat tccatttgta acagatgttg attatgaaaa
     4861 tgaaatgatg gaattggaaa gtggaagtgc ttatccagat agtgaataca attttggcgg
     4921 aggtggcaat agtgacgata gaaacgaagt attggaccaa acgtcgagaa ctggaggatc
     4981 aagcaaggct caaacaagaa aatcagacac ttaaaaaatt aactagtgta tttcctgaag
     5041 cactgaaaga gatacaagca aaactattat cacaagctga cttacacaat atcacttatc
     5101 cagaaatgat ggagttttac agtacaagta atcagaaaaa atatcgtgaa tatgtggaaa
     5161 aaaattataa gtcattaaaa atgtatgatg caaaatacaa agagtttatc gatgaatttt
     5221 ttccaccatt tgactatgca aaagtcaatc gcttattaca aatacgatca gatgtattta
     5281 aaattcttgc agaatatgcg atggatgcag atgtgaatca atatttttct gatcgcttag
     5341 aggaaattct tcaaagaaca tattcttcta atgctaatgt ttttgttcaa cttttaaacg
     5401 ttgatatacc aaattattta ccagaaaatg aaattaaaca ttatttgaac tatccatggt
     5461 caggaaagac attttcaaga agactttggg gaaatatttc atcgcttgaa cagaaactct
     5521 ctaatgctat tgtaaaaagt gttgctagtg gagaaggcgt tatacacgca ttaaacacca
     5581 tgagattaga ctcagaaatt tgtgacatgt ttaagttaga agaatcaaag tataacaaag
     5641 cgatagaaaa tctcgttcga acggagtatg caaaatttgc acaagatggt attgaaaaat
     5701 catatttaga aacaggtatt gaggaataca acgtattgac tgcaaaagat gagagagttt
     5761 gccggatttg tggaggaaag gcaagtaaga atccctataa actgaaagat gctgtcatag
     5821 gtgaaaatcg agcacctttc catagtcgtt gtagatgtac ggatgttcct aatttaccaa
     5881 aattaggaaa ggatattgat gaagaatatg accgtttatt tggcgattta ttagatgagt
     5941 ttgcacatga ttcttttgga attaatttga aacggaggaa gtagaatgaa agattttttt
     6001 gaagcagtac taacaattaa tgtaaatgct gatattgcag aagcctacaa aacagctatt
     6061 gagtctgaga accatcctaa tggcttgaga gaccattgga atggcaatta tgcctacgtg
     6121 gttattggcg atcaaactgt taattatcaa gataatactc cagttgataa gaataccgtt
     6181 aatttaacga ttcaattatt atctcattca ttaccaaatt taaaagaaac agttgattgg
     6241 tatgaaaaga tgggatgtat tgttgttaga actgactaca aagaaggaaa gtctagtaat
     6301 taggcttttt tattttgtcc gaaatgacgt taaactagcg caatactggg cttggttgaa
     6361 tggtggggcg caactattaa aactcaaagc aatgcggggc gtgaaaacga atcgtggggc
     6421 gaaaggagaa tgagcatgaa acacaaatca ttaatgccaa tgaatttgca atactttgcc
     6481 gaaggtgacg atcaaaagtt ttcttttgat gacttcaaat cttttgtgga atccaatgaa
     6541 gaagctcaaa aatttattca gtcacaatct caaagtgttg ccgacaaaca attggaagct
     6601 tggaaacaaa ataacttaga taaaattaaa caggatacca tcaaggaata tgaggaatct
     6661 aagaaaaaca agtcacctga gcaaattcaa ctggaaaaac tacaagctga atttgaagca
     6721 gaaaaagcgt tgcgtgtgac aagtgataat aaagcatttg ttgcagaaca aattgctgga
     6781 ttagaactag atggagagtt aaaagagtct atttctcaat ttatgctaaa taatcttgtt
     6841 agttcggata cagatttcac taagaatgct gttgaaggtt ttacaagtgt tttgaatgca
     6901 attaatgaga aacatgcaga tgcattaaaa gaactacaaa tgaagtctgc atttggtgga
     6961 actcaacaat cgaataacca ggttcagcag aacaatgaaa cattaacaaa tccagaagaa
     7021 caattaggac aaattcttca acaatttaac taggagagtg aaaaattatg aaaaaaacat
     7081 ctttaaataa tttagagtat ttggatattt caccagcgat taatgctatg caagtaccaa
     7141 atacaccttt tttaagctat ttacttggtg ctggaaaaac agagccagca aactcgacag
     7201 aaattaaatg gcgtgaatat gatatcaaca acgatgattc ttctgaaaaa cttgagggcg
     7261 gagaatatcc agatgctgaa tcaggtcgaa cttggtttaa caactatact gaaattttta
     7321 gaaaatcaac ctctgtatct ggtacattag atgctattaa tgtgaatgga gtcggaaatg
     7381 aattaactaa tcaagtagca ctacgtggta tggaaatgaa aattgatttg aaccgaaaat
     7441 tgattactgg tgtaaaagct gatgaaaatg gttctaaagg tcgtcgaatg aatgggattt
     7501 tgaacttgat caattcagca aataaggcag aaacagccac tgcgggtgca gtaacaagaa
     7561 aagatatcga tactttattt aaattgatgt atgaaaaagg ttatatggga gaaaaactat
     7621 gcttgatttc tccagatatg caggagttaa tgactgatga gttagatgga aaatcaacaa
     7681 aaattgttca gttcggggaa agagtaactt ttggattgca aattggaaat atcgtgtcta
     7741 attacggtac aggtattgct ctactagaac catcattgcc aaaaggaaca attgccgcaa
     7801 tcgatactaa ttatgtgaaa ctacgtccat tacgtgaatg gagagcagaa gaacttgcaa
     7861 aaacaacgga ttctagacgt atcggtcttg taggtgaata ctctcttgaa tacaatgctt
     7921 caaactctgg ggcaatttta aatttaaagt ctgaataaaa gggagttagt actccctttt
     7981 ttgataggag gaattacagt ggtaaaaaaa gatgaaacta aaaaagatga agtcgtgaaa
     8041 tatagagtag gtaaaactaa aaattttgtt gggtttgttc atcctaaaac tcgtagattt
     8101 atcacagcag attcaaataa cgaatttatc atttctatag atgataaaga agcaattgca
     8161 attttggaag atgcaattga tgttaatgaa atttaggaag tgatctgatg gatgaatcgc
     8221 taaaaacgga aatcattgag tctacaaaag aagattttcc agatttgagt gaagaacgca
     8281 taactaattt attagaaata attttgctag aaattgaatc atacaacact tgtaaaaatg
     8341 atatttcatg ggaaaagtta aaaagcgtga ttagtgaagt gttgtataaa ataataaaaa
     8401 atgaatcaga aaaaacagta tcttcagtta gacgtggcga tacaacgatt agttatgctt
     8461 caacaacaaa tgatgttagt gagttacttc taggctatgg tgatttgata cgaagagtta
     8521 ttggttgtgg aggattggag tttttttaat gaatgaagca gatattttag aaactactta
     8581 tgaagatagt tgtattattg aaagactgac ggacattgaa gattctaata caaatattac
     8641 tattcaagat tacaaaaaag tatatgataa tcctatttct tgcgctcttt cacaaggtca
     8701 aatcgatgga ctagcagtca tagaagatgg agagatggta aatgtttcaa ctgacacata
     8761 taaattattt gttcatccta agattaaact aaaaaaagga gatcgaataa caataactca
     8821 aaaggccagt ggcttaattt tttctctatt tgctactaag cctttttact atcctagtca
     8881 ttgtgaagtg aatttgatag gaagtgagaa aaatgggtaa tctcaaatat gaatcaaatg
     8941 cagaaaagat cattgagaat tttaaaaata tgactgtaat tgctcaaaaa gaaggaatat
     9001 ccttcgttaa cgattcaatg aataaagtcg ttagtttagc taaaccatta actcctgtaa
     9061 aatcaggtaa tttaaggcga ggatatcgtg tagtaaaagc tagaaaacta tcaagcggtc
     9121 gaattgttgg agaagttata aacaatgaac attattttaa atatgtagaa gaaggtcata
     9181 ggactaaaaa tggtggcttt gtcaaaggga aattcatgtt aactcgtgca acgaatcttg
     9241 caaatatgtc ttatattcct cgaagattta aacaaatggc aataaaaatc gttaagaaag
     9301 gaaagtaaca tgaaagatga aatcattgct gcaatcagta gcaaattaaa agaaatctat
     9361 cctgatggga caatatatct tgattcagtt atgcagtcaa ctaaagattt ttatttcgtt
     9421 ttatcagtaa tggaatctgg aactgaaaat gtaggaattg atattcaaaa tgtttctttc
     9481 ttaattgata ttgcattgat tgataataac cctaatagaa atttaattaa tgaattagtc
     9541 tcacgttgtg ggactttttt taatacgatt acaatcgatg agcaaatatt atttccaaaa
     9601 gcctatttac ctgatgaagc agatggtgtt caacatattc gttttacatt agaatttcca
     9661 caatatattg aatggagtga aagataaatg ggagaaaaaa gaagtaaaac cggaattatt
     9721 tctgtcgaaa aacctacttg gtttcctttg gaagatgaga cagggaattt tccggtatat
     9781 ggtactgcgt tgccaatggg aacagcagta agtatcaaac caacagctaa ttatgaaaca
     9841 acacaagatt atggggattc agtggttcaa gatcaattta cagcttttgg tggtgcagaa
     9901 gttgaactgg aagcaaatgg atatactcat aaagttttat ctacaattac tggagggaaa
     9961 attgttaaag gtggtgcctt gcgttctgga gaagatattg cgcaagatgg tgcgtttgca
    10021 tatagacgta aaaaatcgaa tgggaaatac cgttatacgg tcttttataa aggacagttt
    10081 gctctagatt cagatgaaac atcaacgatt gaaggaagta aagtaagttt tactcatcca
    10141 acttggaagg gttcatttgt agatgtacca ggacttggat atatgtattc agttgatgaa
    10201 gatgatgaag gcgtggataa agcaatgatc ggaaattggt ttacaaaagt agcaattcca
    10261 attgaagaag cagaactttc aggaggtaca gaataatgtc aaaatatcaa acaacgatta
    10321 aattaacgaa aaaagacgaa gaaggtaaat atgagcaagt acaatttaaa tctgctgaat
    10381 ttttaccagg aacagttgta gaagatgctg caggagttat ggaagaaatg caaacagcga
    10441 ctgataagca atcagttaaa aaagctttaa gtcgtgctta ttcatttatt gcagatactt
    10501 tatttgaggg acaatttact ggtgaagatt attgcaaagg aattgatgct cgtgagattg
    10561 cctcattgac aggaaaatta ttgaagtctg ttactgcagg ttttgatgaa acttatacag
    10621 agacgaaaaa aaagtaagtg aggcgctcaa gtcaccttca tttaagtatt cgattactta
    10681 ccgagaatta gatataaaga cgcaattact cgaagcaggt tggacgttac cagaaattga
    10741 acgtactgac ttggatgagt taatgcgtct ttttgctttt agagatgcgg taaaagagca
    10801 tgaagatgtt gagtactatg ataatttcac tcaattttag gaggtgatac tttgaataac
    10861 gatgacctaa ttctgaagat gatactagat gaatctggtt ttactgccgg tatgaataat
    10921 gctgtcaaaa agttgaactc ttttgatgaa acaatcgaaa gaaaaagtag aaatagtggc
    10981 agttcattag gtagtatttg gaaaatattt gctggaagtt ttctagctag cggagtaact
    11041 agaatcgtag gagctggctt tgatctaatc aagggttcca taagtggagc ggttgatcga
    11101 gtagatacga tgaataacgc tctacgaaat ttccaaaata tgggatttag taattcagaa
    11161 attatgaaga atatcggaaa gaatgggctt ttatctcaag gtattcaagg acttcctact
    11221 gctttgaatg atgcgataag tcatgttcaa cttcttgctt cttctacagg tgatttaact
    11281 cgttcaactc aaatatttaa agctttaaat gatggaattc ttggtttcgg tggttcaact
    11341 gatcaagtta atgaagctgt tattcaatta tctcaaagtt tctcaaacgg aaaagtagac
    11401 gcacaaactt ggaactcaat gatcaacgct caacttggac ctactctttc tgctattgct
    11461 aaaaagatgg gaattacaat gggagatctg aaagaaggtt tatctcaagg taagatttct
    11521 gttgaagaat tccaaaatca attaatagaa atggatacca aaggtggcgg aggacttaaa
    11581 tcattaagtc aaatcgctaa agattctact aagggaatta aaacctctat acaaaatgca
    11641 aaaacagctg ttacacgtgg tgttggtgag gtaatagaag gattaaataa agcattagta
    11701 gattcagatt taggtggatt taagggaatt attgataaag tgggcagttc aatggaatcg
    11761 ttcttaaaag taattgctgc aaatattcct acagcagtat catttttaag taatttattt
    11821 aacgaaattc aaaaatttgg ttctgctttg aaattcatga tgccctttct tgttcctgca
    11881 gctaccgctt ttggagcgtt catgtttcaa cttaaaggta taccagcaat aataaaaagc
    11941 ttcaataatt ttaagaatgc cataattggc gttggaaatt cattaaagat tatgggggca
    12001 atagctgctg ctaatccatt tgttttaatt attggtgcag tcgttggtgc aatagctgtt
    12061 ttcggttact ttatggcaac caatgaagag cttagaaaca aggttatatc tatttggaat
    12121 gatgtgaaag attccgtaat tggtgtatta aaaaatataa aggactgggg aattgatact
    12181 tggaattctg ctaaagaaat ggcatcaaat gcagttgagg gtgtcaaaga tgcttggtca
    12241 ggaacaaagg aatggttttc taacacctgg aaaggtatta aggatggggc cacaggttta
    12301 tttgataaaa cagtagagac ttcaagaaat gcagtcgata gtgtaaaaaa tgcatggtct
    12361 aatatgaaga aatggttttc tgatacttgg caaagtataa aagattcagc cagagaaaaa
    12421 tggaatggaa tcaaaggttc tattatgtca gttgctggtc cattgattac aggtataaag
    12481 aatgcatttt tacatgttac tttttatcta gagaccttat ggaataattt agttgagatt
    12541 ggtaaaaacg tctttgagat tttaaaaaat gttatacttg cgccggtttt gtttattacc
    12601 tccatgattt ctggtggatg ggaagaaaca aaaaataata tgattgctgt ttggaataat
    12661 attaaagaaa gtgccataaa tatttgggaa tctataaaga atatatttgt aagttatttt
    12721 acaaatattt attttgctgc actcaatatt tggacagggt tcaagcttac attgataaat
    12781 atttggaatg aagtggtaaa tcaagctaaa tcgatttggt taaacataaa gtattttttt
    12841 attaatcttt ggattgatat aaaatatttt gcaattcaga aatggattga attgaagttt
    12901 tctattattc aaacttggat cgatttaaaa tataatgcca ttactacttg gaataatatt
    12961 aaacagtttt tcaaagatac ttggaaaaat attaaagata cggcatacaa tacgtggatt
    13021 tctataaaaa ataccatgat taatacatgg aataacatta aggactcttt ctggaatatt
    13081 gttactggaa ttgttaattc tgctgaaaat gcatggacaa atctaaaaaa tggtgtttca
    13141 aatgctatta atcgggtaaa agaaatcttt aattcgttaa gggaagtcaa tttatttgaa
    13201 attggcaaga acatcattga tggacttata aatggtgtaa aagaaaagtg gaatgctttg
    13261 aaagatacta tcaaaggtat tgcaggtaat atcaaaaatt ggattaaagg agctttagat
    13321 attcattctc catcaagatg gatgcgtgat atggttggta aaaatattgt tcaaggtatt
    13381 atcgttggta ttgataaaga gcaaagtaag ttagatcaaa ccatgacaaa tttagtaaaa
    13441 acaccgtctg ttcaacctgt agtaaatgga ataagtcacc taccaattac acaaacaaag
    13501 caaaatatat ctgctagtga aacaaaagaa attcatttac atttaaatgt ttatggagat
    13561 ttacctgatt caatggttcg gaagattacc acaaaaatta aaacagaatt gacaagacaa
    13621 atgaaacgag atgctggtgc agtaggagga acattatatg caacttaaga gaggacaatt
    13681 ttttattaat caacattatt cttctgaatt taatgtgtat attcaaaaca ggcctgcttc
    13741 tgtttcagct agtcgagtaa ttgaattgag agagcgagaa ggaaatgatt ctatcattat
    13801 tgataaaggc tattacaaaa atgtgactag aaagattgag tgttactata aagcaccttc
    13861 aattgatatg gtgcaggagt gggaagatcg aatcactgaa tggttagata tgtcgtctta
    13921 tagtgatttt attctttact atgatgaaca atatatttat caagctgtag taatagaagg
    13981 acctgaattt aaaggaacaa gaaaaacagg aaatattgtc ccttttgaat ttacagtgag
    14041 tattcgacca tttaaggaaa attacaatgg tagatttact attcgacaaa cagaaacttt
    14101 tgaaatttat aacccagaga agtattcttc aaaaccgctt attaaattga gtggttctgg
    14161 agatgcttct ttttatatta ataaggataa atatgatttg aaatcgttgg acagagaatt
    14221 atttatagat tctaaattag aagaggctta tcgaaaatta gatggtaatt tagaacatca
    14281 ggatcaggtc accttatttt tagattttcc atttttatat cctggaaaaa atgaaattaa
    14341 atggacgaaa aatattcatt catttgaaat aatgcctagg tggtggagaa aagtatgaaa
    14401 ccaagaatat atagtcctac tgaaacagat ttctcaacga atggcttagg aattttaaag
    14461 gattgtacaa gatgtggaat atatgaagta gctaatggaa aatatgaatt agagttggat
    14521 tatcctttag gaactagatt tgatgaatat tttgaaaatg actatcaaat aaaagcaaag
    14581 ccaaacgatc aagaagagta tcatatcttt tttattgatg ataaagatat agatactttt
    14641 ttaaatacag taactattta tgctcagagt cgtacaaatc gacttggaag acgggtagtc
    14701 actcttgtgg aagtggactc taaaactggt caagaagcga tatcaattat tgaaactaaa
    14761 atggataaaa aatctgacat acgactttat tctgatatta cggctgtttc tagcacaatc
    14821 tttgaagcga gaaatgtttt aaattgtatt gctggtgaac aaggatcatt gcttcaatat
    14881 tggggcggag aaattaaacg tgaaccattt aagctttctt tgttaaagcg aagaggtcgc
    14941 aataatgttg gaacgattcg gtatggaaaa gatatgtctg gtttgaaggt caaattagat
    15001 tggacaggta taaaaacaag aattattcca tatgctgatc ctcaaagtga agtaggtacg
    15061 actaatcgaa tttatggttc gccagtagat agtgcctata ttaataacta tcctgatgtc
    15121 tatacagaac atgttcagtt tacagaagaa caaggagtaa aagacattaa gagcttaaat
    15181 aaaatagcta aaaattactt taaaacgatc aatcctggct gtgataagcc taaagtttct
    15241 attacggttg aatttgataa gttgactgat agtgaagaag cgaaagaatt tgcgaagatt
    15301 agaaattatg gtctgtttga tacatttaaa atatatcata aaaaatataa tatttatctt
    15361 gaatcaaagg ttagtggact acaatacgat tctttatctg aaaaaacttt gaaattagaa
    15421 gcaggagaca ttcaagttgc tttttatcag caacaagctg taactattca ggataaatta
    15481 aaagattatg caacgaataa ttatatgagt gattttaatg attatgtttc ttcaatgatt
    15541 acaggtcaag gcagtgcagg aggatatgta gttttatggc caaaagaaaa accttccaac
    15601 atctttatta tggataatcc agatttagaa aaggcaagag aagtactaag aatgaataaa
    15661 aatgggattg ctttttctaa gaaaggatgg cgggggcctt ttaattcagc ttggacatta
    15721 gatagtatat ttaatgccaa ttttatacaa actggattaa tcaaagcaga tatctttcaa
    15781 aattctttta acaagactgg agatgtattg aaattagtta atggactact ccaaatttgg
    15841 aacaacaaaa agaaaataat ggagttaact aaaaaaggaa tggaattttg gaattctaag
    15901 ggttcaattg gaacgattgg aacaactgat tctgttggta atccttttcc tggggcttct
    15961 actccaaccc ctattgaaga taattcttta gttattcgta caaatggaga cggcaaatat
    16021 attttgattt ctcctaaagt aggaaaagga ttagttttat taggaaatgg taaagcaatt
    16081 tattttggag acttagatgt acaaggaaaa cttacagtta aaggaaaaga aataattcct
    16141 ggacaaggtg gtggtccatc gggaggtgga gaatctactg gtgggtatcc tagtgaatta
    16201 aaaacagatg cagaaaagag agcttggaga atttacgata ttttgtgtaa taacggattt
    16261 acgaaacaat ctgcatgtgg aatattgggg aacattcaac aagaaacagg aggaactttt
    16321 gatcctgata ctgttcaaat aggtggacca gcatacggat tagttcagtg ggatggttct
    16381 tcatatcctc ttgttggtcc agcaacatgg gatggaaaag tttatgttca aaacttattt
    16441 aatgctgcag gtattaaaga accaataacg agcttagatg cacaagttcg attgcttatt
    16501 tggacattta caaatggaca atggatgggc gtagtacaac ctacgacggt tgatggattt
    16561 aaggcctgta ctgatccaag acaagcagca tatgcttttg aacgaaacta tgaacgtccg
    16621 gcagcgacac atcctgaacg tcaagattat gcagttaact ggtataacaa atttaaagat
    16681 ttaaaaccag gaggagctac tggagaagca ggactaaaac atttagagtc tttgattgga
    16741 caacgaattg gcaatggtca gtgttatggc ttgtctgcag aatattcagg atatctgggt
    16801 ggttgtggca tgggtgctgg aacaaaatat ggtttaactc atgtgatagg aaatacttct
    16861 gcagcatctg atattggtat tgcctatgat tggtctgctg ttggttggaa agtgattcaa
    16921 aaccctagat atgatcaatt agtagttggt gcaattatta attgggcaag aggtggacaa
    16981 gtgggttcat ggtttgcaga tggaacttat ggacatactg gcgttatccg aggcttagct
    17041 aatggtcgta tgcaaactta tgaacaaaac acagagttag gtatgatttg tggaaagtta
    17101 gatcgccagt attatagtgc aagtgcaatt tcttccattg tcataccacc aaaataggga
    17161 ggtgatttaa tggcaaagtg gaatgtcata ttaagtacaa cagaacccta taattacgtg
    17221 gggatgattc aagttcgaca aggcaataag aatacagagg ttatggaagc gactatagtt
    17281 gaaaatggtc ttccctacga tttatcagaa tgtaaggtat attttgaatc agttgtaggt
    17341 gggaaatatc cagtccaatt agaaacaaaa attgtggatg ctaaaaaagg gaaaattaac
    17401 tatatttttg ataaatattc catgcagtgt ttacatcgac aaacagccaa tttcattata
    17461 tttaaaggag aagacttgat tggaacaact caagacttct cttattttgt cattaatgct
    17521 gtttcaaaaa cagaaggaga aatgggttct tattggcaat caatcgaaga tttaattgcg
    17581 gatatgacgg actttattaa tgaaaataaa ggcgatttta cggactggat gaatgaaagg
    17641 aaagaagaat ttgaacgttg gagacaagaa caggaacaca gtttccaaga ttggagagaa
    17701 ggacaagaat cagactattt ggcatggttt gaatcaatca aggatatttt aaagacgatt
    17761 gatccaggtg gagtcatgtt agccgaacta acggatgcgc gagtagatat tcaaggagtt
    17821 cgtcatgcgt ctatttcaga gcgtttgctg gcagatatgg actatttata tcagaaattg
    17881 cgagcaacgc ttttcacgat tgaatacggg gagattgaag tgactgatat tttgcaggat
    17941 gatctctttt cagataatca tgaagtcgaa aaagttggaa ctgtagcatt cccgattgaa
    18001 gaaggagcct tgatcatcgc aaccgttgat gatccaaagc aaaatgtgtt cactcttgag
    18061 aaagttgggg tgatctaatg gctaaaacta aacgaatgat ggaaacggat gaaaaaacgg
    18121 gtgtacaacg ccaattcttt ccaatcacac atgcttccgc agttcttggg ttagaagaaa
    18181 taatagcagg agaagcaaca gttttatctg ttaatggaaa aattggagcc gtcgtcatta
    18241 ctaaagaaga tttgggatta gagaatgttc tcacagaatt accctatgca agtgaagaag
    18301 atgacggcat tatcacggca gaaatgtatc aaaaaatttt aaacagtgga gaaggtgact
    18361 acgtgttgcc agttgccact atcgaccgtt tgggtggcat aaaagttggt gaattattga
    18421 cgattgatga gacagggaaa gtctctgcag tcagacaatc tgatgtcaat ttttcgctgg
    18481 agttaaaaga aaaactcgat tcactgaaaa attatactgc tggagaaaac atcactattg
    18541 atgaagatgg aacaattagt tctacaggtg gtagtgggac tggtggtgtc aatcagtcat
    18601 atgtagatca aaaattccaa gaagctgtaa atcaagcaga aaattacaca aacgaaagaa
    18661 ttccaaattt tacttttgaa aaaattgggg aggtatagag aatgacagat atcgtaaaaa
    18721 taaaacaaag caatgtacag gtttatccac aaactcattg gaatgctata gaaggcaaac
    18781 caacaacggt gaagggagat aaaggcgatc ctggccaagc agcaacaatt accataggaa
    18841 ccgtttctag tggttcaacc gcttctgtta cgaatgtagg aacatcatct gcagctagat
    18901 ttaattttgt tttaccaaag ggagataaag gtgatcctgg aataaatgcc acaactacag
    18961 ctgtagctac aactacagca aatgggttga tgtcgtccac agataaaact aagttggatg
    19021 gaattgcagc tggagcacag aaaaatccag gtaatgctac aactacgaca gcaggtttaa
    19081 tgtcagcaac tgacaaagct aaactcgatg gattagccaa tattacattt gagaaagtgg
    19141 ggacggttta atggctgata ttgtgcaatt aaaagaagac ggagttgcta aatacttaaa
    19201 aacgcatgta gaagctattg atggtaaaga agcattggtg cagacagatg gagaccaagc
    19261 cattgcagga cataagaatt tttcaggttc tgtaacaatc aataataaac gtgttttgac
    19321 gactgatgat aacagatatg aagtggtaaa tctggttgtc actaacggta atacagggac
    19381 agcaaagctt tatcgtgaag gaaaaacagt ttctatatat tttgtggctt taaacggaaa
    19441 aagtagtggc gggaatgatt cggttatttt aactgttcca gaaggctatc ggacaccaat
    19501 tagttttgaa caactggttg ggtcaataga ccgttctact ttgaacagtg ctcaactatc
    19561 tattggcgca gacggagcca ttaaatggag aagaaattca agttatggat cagcttattc
    19621 atttgttatc acttattcaa tttaagggag gaaatctaat gaaagtagtt tacaaatcaa
    19681 tcaagcctta cggattcgag caaatcattt tgaacaatca agaaaatatc cctgaaaact
    19741 gtacagagat taaaccacca gttcctaact ggagaccaag atttgatttt gataaaaaac
    19801 agtgggttga gttagctact gaagaagaga aaaaagggaa tgctgttgat agcgtagatg
    19861 aattggctaa tattaaggca ttatacgaaa cgctgaaggc agaaaatgat gaattgaaac
    19921 agctaaattc taaagcaatg ctaaacaatg tagcaatcaa gcaagaaaat gtcttattga
    19981 aagaaaagtc agaaagttta gcgcagttga attcaaaaac gatgcttgct tctgtacaaa
    20041 ataccaagga aatcgaagaa atcaaaaaac aattacaagg tgggaagtaa catgtattca
    20101 tatgaagata tcaaactaat gtatgactgg ggctgtttca ctaacgaaca agtaatggtt
    20161 ttcgttccgt tgtgcattac tgaagaagaa gcagataaaa tcattagcaa agaagagagc
    20221 gcatcttaat tgatgtgctt tttattttga ttcaaggagt tgtcacatga ttaatttagg
    20281 ggaatgggga gcgatagcag gatcaataac cgctatcgtt tctttgattt tattagtaat
    20341 aaaaccaatt actgcatctt tctcgaagat tactgagact ctttcaaaag taagtcacaa
    20401 tttagatttg ctgactaaag atttagaatc gagcaaatca gatcgattga tgattcatga
    20461 agaactaaag aaacacgatg aaagattaga tacacataca gaaaaattgg t
//
LOCUS       DAFENC010000047        20497 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.049, whole genome shotgun sequence.
ACCESSION   DAFENC010000047
VERSION     DAFENC010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20497
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.049"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(9..482)
                     /locus_tag="LP493_002246"
     CDS             complement(9..482)
                     /locus_tag="LP493_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBL2134368.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(587..1450)
                     /locus_tag="LP493_002247"
     CDS             complement(587..1450)
                     /locus_tag="LP493_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBL2134369.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(1646..3745)
                     /locus_tag="LP493_002248"
     CDS             complement(1646..3745)
                     /locus_tag="LP493_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBL2134370.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            complement(3965..5074)
                     /gene="rpoD"
                     /locus_tag="LP493_002249"
     CDS             complement(3965..5074)
                     /gene="rpoD"
                     /locus_tag="LP493_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBL2134371.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(5098..6939)
                     /locus_tag="LP493_002250"
     CDS             complement(5098..6939)
                     /locus_tag="LP493_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBL2134372.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(7121..9436)
                     /locus_tag="LP493_002251"
     CDS             complement(7121..9436)
                     /locus_tag="LP493_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBL2134373.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(9621..10481)
                     /locus_tag="LP493_002252"
     CDS             complement(9621..10481)
                     /locus_tag="LP493_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HBL2134374.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(10540..11061)
                     /locus_tag="LP493_002253"
     CDS             complement(10540..11061)
                     /locus_tag="LP493_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HBL2134375.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            11339..12100
                     /locus_tag="LP493_002254"
     CDS             11339..12100
                     /locus_tag="LP493_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL2134376.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            12126..14717
                     /gene="mprF"
                     /locus_tag="LP493_002255"
     CDS             12126..14717
                     /gene="mprF"
                     /locus_tag="LP493_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBL2134377.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(14905..16092)
                     /gene="tuf"
                     /locus_tag="LP493_002256"
     CDS             complement(14905..16092)
                     /gene="tuf"
                     /locus_tag="LP493_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBL2134378.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            16460..16816
                     /locus_tag="LP493_002257"
     CDS             16460..16816
                     /locus_tag="LP493_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBL2134379.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            complement(17057..18061)
                     /locus_tag="LP493_002258"
     CDS             complement(17057..18061)
                     /locus_tag="LP493_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBL2134380.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            18227..19078
                     /locus_tag="LP493_002259"
     CDS             18227..19078
                     /locus_tag="LP493_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBL2134381.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            19095..19340
                     /locus_tag="LP493_002260"
     CDS             19095..19340
                     /locus_tag="LP493_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134382.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            19527..20231
                     /locus_tag="LP493_002261"
     CDS             19527..20231
                     /locus_tag="LP493_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134383.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
BASE COUNT         5804 a         4202 c         3584 g         6907 t
ORIGIN      
        1 ctagacactc agacggactg gtttcttttt tctttttcat agcattcctg acagattcca
       61 tggaacgtta gccgatgatc ttttactaaa aaatgataac gttcttctac tacttgctcc
      121 acttcaagta aaagatcctc ttctacttcc tcgatcgtgc cgcagttcaa gcatagtaaa
      181 tgatgatgga aatgtttggc gccttctttt ctcaaatcat aacgggctaa tccatcatta
      241 aaacttactt tatcgacaat tttcaattct gtcaagattt caagggttcg ataaacagta
      301 gcaagtccaa tttccggact cttttttttc actaaaaaga agatttcttc tgcagataaa
      361 tgctctttct cattttccaa aagcacaagc agagtagctt ctctttgcgg tgtcagctta
      421 aaccccgctt catgtagctg ctgttttgtt tttttcatcg ccgaaatagc attcatgacc
      481 atttactcaa ccccaacaat ttataataat tacaaataaa aaaagatata acactatgtt
      541 aattaaaatt attataagct agttaagaaa aacatgcaag ggattctcaa ttagattttt
      601 tgactagttt tgtcacaccg ttttcttgtg taatcaatcc ttgtttcaaa agattaccta
      661 atgcgcgctt aaatgctcct ttgctgatac caaaagcttt catgatttct tctggatccg
      721 atttatctgt aaagttgatt tgctgatctg cagaacgttc taaaatggtt aaaatcattt
      781 gtgcatcatc tgatatagct tcatatgctc ttggcttcaa tgaaagattc agtacaccgt
      841 ctggtcggac accaatcact cgacctttta tctgctcgcc tagacgaggt tcattatatc
      901 gttcagaagg atggataaac ccaagataga aatcttccgt taaaacgtac gtacctgtta
      961 atttcaagcg gtatgctgtt cctatcacat ctttgttttt catttcttct gttccatatt
     1021 tgcttaaaga tttgaatatt ttttcatctg ctaaactgcc ccaaatacgg tcttttgcat
     1081 caactctaag ggaaatcatc aagcgatccc cttttttagg ccatagctct gtcattgtcg
     1141 gcaattcatc aagagatacg acaaagtctt tatctggaag accgatatcg acaaacgcac
     1201 ctaaatcttt tcgtgtagca gtaacgattc caaaagcgta atgaccgata cggcttttag
     1261 gaatttgtgt agtgatccga ttttcatgtt tttgattttg gtaaccgaat ccttcaactg
     1321 cttcaccgat tttgtgttca ccttctgatt tgcttaagcc aaaggtttgt ccgttttttt
     1381 ggacaaagta gtttttttca ttttcatcaa taataatacc tgtaaatata gttgctaata
     1441 aatcgttcat ttttttctcc ctctatagtg aaaggttttc ttaatacatt tctttgctat
     1501 cataacataa tgttatctac ttgaatagct gagccttggt ttggaaaggt gaaaaaagga
     1561 gtatgacaac agttgtgtca tactcccctt tttcgaataa acggtgttaa acggcaggct
     1621 cacagcctct ttcatttgcc taaaattaat tgctcccatt tcctccgaac catccagttt
     1681 tacagttgat ggttacgatg taaaatggca aagcactttc tccaatgcct ttcatcaatg
     1741 cagattttgt tgaagtggca tatagattat aatagccttc cccattttcg attctggctt
     1801 tttctaatct gtaacctcct tcaacgatat atccacgttg gatacatgta gcaatcactt
     1861 tgctttggac acctggtgcc cacgtccatg ctggattaga tgcatcggca atatcacttg
     1921 ctctggcaga tttgattggc tgattcgctg agtttgaaga ggaaggggtc gaggatgccg
     1981 cttcttgctg tgctgcttgt gcgaccgcag cttgttgagc ggcttgagct gcagctgctg
     2041 cttgagcggc ttgttttgct tgttcttcag ctgctttttt cgcttcttct gcttttttct
     2101 tttcctcttc ttcttttttc tctttatcag tgagcatctt atctacttgt ttcaattgtt
     2161 cattcaactg agcagataga tctgtatttt tcactttttc tactgcttct tttgccgtct
     2221 tgtattggtc gcgtgttgct gaatccacta cttttccgtc tttaaagact atagctgttt
     2281 tttctttagc tgtttgcaat tcagcatatt gatttttagc ttctgtttgt gcttgttgaa
     2341 tcaattttcc aaaatctgtg ttatccgttt cgattgcttg gatctcttta tctgctttca
     2401 acttgatgtc atctgctaga tgatcatcga cgatggcagg tgctatgaac cactcattca
     2461 ctttttggat atctcggatc ttagattgga tatcttggta agttgtttct aactctgaat
     2521 atcctttttc attcttaaga ctggataaat cattttttag ttttgataaa tcttgatgaa
     2581 tcatatctgc acgaataaat tgatggtgat catctgtata aaaggcagca agtttctcat
     2641 gaagttcttc catttgttgc tgtctttttg cttctgctgc tacttcggct tctacttttt
     2701 gatgatggtc ataataagcc cagcttcctc caccgagtag aagtactgct gctaaaacga
     2761 gataaggtac tttttttgat tttttctttt gcgctttatc tggatctgtt ttttctaagt
     2821 ttgattcttg atgtgttttt tcagtatctg gcacgattgt tattgatttc gcttctgctt
     2881 caaacagctt aggctggttc tcttcttttt ctatttttgc ttcaagatca gtaccctctt
     2941 tgcttacaga ttgattttca gcatcggatt cactatttat ttcatcgggc tctgttgact
     3001 ttttgtctgt gttttcgagt atttcttttt tctctgcttc cggcagttta ttcgtttttt
     3061 ccttttctaa ttgtttttca gtaaatactt cagttttttc tgtgatatcc gtttttacgt
     3121 cttttatttt tactgtttct ttacctgtgg cgttttctct atcagagtct ttttcagttt
     3181 cttgttcctt ttctggctct actttgtttt cctgtgcaat tttttcactg atcattttga
     3241 gcagctcttt cgcgtgctct tcttttgtat cttcacgatg tgctttgata taagcggata
     3301 gtatcgaatt ttcttcctca ttatcgacga tttctttcag ttcagctact cttctttttt
     3361 gttttgattc aagcgtttct tcttgattct ttcctgattc ttccgaagtc tcatgaacag
     3421 ttgctttctt ctgttcattt ttctctatat tagttacttg atcgtgagca ggtggttctt
     3481 cgtcttctgg ttctgctttt tcgaataatt ccattacaga ttctagaggt aaatctttca
     3541 attccgacca ttcgattgga tcgtttaatt ctgtatcagg aaagactgca tcttcagttg
     3601 atttatcctg catagctgca tctgtatttg tttcttcaat tgattctttt atttgctgat
     3661 cttctgcagt tatttgatga ccgcagtctg gacagatagt attctgctcc atttttttcg
     3721 atccgcaatt tggacatttt ttcatcactt agcgatcggc tcctttacta ggtttacgct
     3781 accatttaat ctatcatatt ctatacgtca cgccaatagc ttatttttag gatttactta
     3841 aaaataatga atgaatttcc ttcctataga aaaaaaagct tgagactgcg tagtctcaag
     3901 ctttttttct tttaaaataa accaaacagt tttactgatt tctcttctgg tcaatagtcc
     3961 acgcttattc taagaaatct tttaattgtt ttgaacgaga aggatggcgc aattttctta
     4021 atgctttagc ctcgatctga cgaatacgtt cccgagtaac accaaatact ttccctactt
     4081 cttccaatgt tctcgtccgg ccatcatcta aaccaaaacg taagcgaagg acattctctt
     4141 cccgatcagt caatgtatct agtacatctt ccaattgttc ttttagtaac tcataagctg
     4201 cgtgttctgc tggacttgtt gcttcctggt cttctatgaa atcacctaag tgagagtcat
     4261 cttcttcacc gattggcgtt tcaagggaaa caggttcttg cgcgattttc aagatttctc
     4321 ggactttttc tgttggaaga tccatttccg caccgatttc ttctggcgta ggttctcttc
     4381 caaggtcttg cagcaattga cgttggatac gtatcaattt attaattgtt tcaaccatat
     4441 gaactggaat acggatcgta cgtgcttggt cagcgattgc tcgagtgatg gcttgacgaa
     4501 tccaccatgt agcataggtt gaaaacttaa atcctttgcg gtagtcaaat ttttcaactg
     4561 ccttcatcag tcccatgttt ccttcttgga tcaagtcaag gaactgcatg cctcgtccta
     4621 cataacgttt agcgatactt actactaaac gaaggtttgc ttctgccaga cgctgtttcg
     4681 cttcttggtc gccttcttcg attttcaatg ctaacgctac ttcttcttcc gcagttaaaa
     4741 gggagacacg gccaatttct ttcagataca tacgaaccgg gtcattgatt tttacaccgg
     4801 ttggcgcaga aagatcttct gtttttgctt gttcagcttt tttctcagca ctcttcaagc
     4861 tgtgaattga tggatcacca ttttcatcca ccacactgat acctgcgtct tcaatctttt
     4921 ggatcaattt gtccatttca tctgcattca aagtgaatgg tgtagcaagc tgattggata
     4981 aatcatcata tacaacttgt cgtttgggtt tgttttcttt gatgaaagct gctactgctg
     5041 cttcatacgt ttttttatct gttccatttg ccataaaaga aggcccccct tgagtagcta
     5101 tttggcttgt tttaactgtt tcgttaaatt gatgatttca atcgtcaatt caagctcaag
     5161 ctgtttgttt ccagttcgtc tggcttcttg ctgcatttgt ttttttaatg ttatttcatc
     5221 agctaagcca gatttgctga tcacatctag caagtcttgg atttctcgtg gcgaactttc
     5281 ttctgccacc ggtaaatatt cgatttccac caccaaccgc cttaaatttt catcttgcaa
     5341 aaagtctaaa aactctgcaa ggttgaattc ataatgttgt gagacatatg catcgaataa
     5401 aaaataaact tctgcatatg catcatgaat aaactgaaat tctcgttctt ttaaaatatt
     5461 acggacagaa acttctttaa atgcacgata taatagaatc tgctctgcct tttctacttg
     5521 cgtcaaaggt ctctttttcc gtgcagtttc ttgtctcgta acctgagtgt gttgactttc
     5581 ctgaggttct tgacgatttt gctgatttgt ccttcgaaga tcgcgcagtt gtttttgtat
     5641 cgtctctctg ccgatctgaa actctgttga cagttgagat agatacatat cttgttcgat
     5701 tggtgaaaca actcggctaa gttcaactag taattcttcg aggtattcga tcttgtcttt
     5761 ttcattatct aaatttttcc cttgttttaa ataacgtgat ttaaaagtaa agactgtttc
     5821 gcgcccatga gccactaatt cttggaaaga tgcttctcca tacttacgga gatattcatc
     5881 aggatcaagc ttttctggaa cgactacgac agaaagtgct aatcgactgt tttgccgaag
     5941 caattcaatc cctcgattgg ttgcttcaaa acctgcgttg tctccgtcat agcaaaagac
     6001 caattctttc gtcagctttt ccatttgttg gatctgttga gctgttagac ttgtccccat
     6061 agaagctaat ccagttttga taccagcctg ccatgcagca atcacatcca taaacccttc
     6121 gaacaacaaa atttctccgt ttttccggat atcgcttctt gctttatcaa gattaaataa
     6181 aacttgtctt ttattgaaca gttctgtttc tggactattc aagtatttgg gctgatcttt
     6241 ttcctgccct ttttcaggtg caagccagcg tcctgaaaaa ccgatcgtct ggccttgaga
     6301 attacgaagt ggaaacatca ctctttgata aaaacgatca gacatacggc catcatcatg
     6361 cgtgacaaac aatccagagc gttctaacaa ttcatttgaa attgattcat tcttgaatac
     6421 ttgctgaaga aaagaacgct cattaggtgc aaaacctatg ttgaattctt caattaattc
     6481 taaagacaac ccacgacttt gcaaatattc taaagctggc tgtccagctt ttgtatgcaa
     6541 tagcatgtga tgatagattt ccgctgcttt ttcatgagca gcaatcagtt tccccgtagc
     6601 agattcagga ttttggacag ctatagtacg ctgacgccat tgatcttcta acggtatctg
     6661 ttcgaagtct gccactttta ccactgcttc tggaaaactt agaccttcta gttcttgaag
     6721 aaaagtaaac acgtttccgc ctttaccaca accaaagcaa tgaaaaatct gcttgtcttc
     6781 tgcaacagaa aaagacggtg tacgttcttc atgaaaagga cacagcccca agtaattttt
     6841 accagacttt ttcaactgga catattgtcc aatcacctca acgatattcg tttgactgcg
     6901 tactgtttcg ataacctctt gaggaatccg ttgagccatt ttttcacccc ctgctctatt
     6961 gatatctttt gggtttaaca gaagatattt caggagaata accggtaaaa aatcgcacta
     7021 actgaaatca gtgcgatttt aaaggacaca attatacatg tttgattgta tcatatttca
     7081 ttgctttttc aagtataaca catttctatc tcattaagca tcaatttgct actcttttca
     7141 gtaactgatt ttgaatatca gccttccagt acaatactcg aagaacaata tttacgagca
     7201 tgaatacaaa gaagtatcct acgctctctc ccaaccctaa gtttacttcc aaaattccat
     7261 ggaacagcat tgcagctaca tatatcccta cgatcgtcgt tactgctagg aagatgcgca
     7321 atgggttgaa gggataacaa gcttttacaa ctgccatgca actgatccca atcagcaagt
     7381 aatacatcaa agtagtagtt tcagcatttc cccatgcgaa tgtttttcca agtagataca
     7441 ccgcaatgat attcactact acaagcaagg catttggtaa agcattaata agtgctgtag
     7501 gcaaataacg gtaagtgatt tttcttttat cttgttcaaa agataaaaag aaggaaggat
     7561 acccttcaat cgctaaatca atcagcgtga tttggatagg gataaacgga aatccaattg
     7621 ctgtaacggc acatataatc gataaaataa atgaataaat cgttttgata aaaaagatgc
     7681 ctgagacttt cgtcacattg ttgaccactc ggcgtccttc aaacaggact tctggcaatg
     7741 tagtaaaatc agagtccaac aataccagat tcgcaatctg acgtgttgct ccatcacctt
     7801 ctgccatagc aatgctgcaa tctgcttctc ttaacgccaa aacatcattc acaccgtcgc
     7861 ctgtcattgc aaccgttctg ccgctttctt tcaattcatt taccagcaat ttcttttgct
     7921 gcggactcac tcgtccaaaa accgtatagc gatgagcagc ttctcgcact tccatttctt
     7981 cagtaatttg agaaagatcg acatacgcat cataattcgg taatcctgca cgtctagcga
     8041 tattggagac agtaaaagga ttgtctccag aaatcacttt cagatccaca ccttcctcat
     8101 gaagataagc tagtgtttct tgagcgtttt ttcggattgg atcatcgatt tcaaacagag
     8161 caaccggctc aacaaatgct ggtttttctt cgttcaattg ctgatttgga gcgatcccca
     8221 acataagtac gcgatagcca ttcgcttggg ctgtttttag actgtccgga agccgatctt
     8281 cttccaccaa acgttcaggc gctcctacgt acacgactcc cagttctgga aattccatcg
     8341 cgccccattt gcgatcagaa gaaaatgcga ctttgtttgt cacatcatac cgattagaaa
     8401 gctcaaaata atctctcata gcccgcatag tgatgttgtt atcactgctt tctgccagat
     8461 acgtccccat aatttctggg atggctttct cgtacagcgg atgtagtgct tctacccgct
     8521 ggatactcat tttcccttca gtaatggtcc ctgttttatc caagcataat gtatcgacat
     8581 gggccagcgt ttcaattgaa tacatgtctt gaacaaggat tcgttttttt gccagtttgg
     8641 ttacccctgt cgttaatgca atacttatta gcaataccaa accctttgga agcatgccta
     8701 acaaagctgc tgcagatgca ataacagaaa ttttgataga agcatcgcgg atgaacagtg
     8761 cttccaaaaa tagtatgatc cccaaaggaa taatcacgaa actagtgaat ttggatactt
     8821 tgcgaatcga atctacaagt tcagaacgaa tagctttgtg agtctttgcc tcgctagtca
     8881 agcggacagc ataattatct gcacctactc ggataacttc agccatgaca gaaccgcttg
     8941 tcaaaaagct tccagaaagc aattcagctc cagtttcttt gacaatcaaa tcagattcgc
     9001 ctgtcaaaag agcttcattt gcttctgccc gtccagatat aacctgtaaa tcggctggta
     9061 tctgttctcc tgctccgatt tttaccaaat ctcctaatac cagctcttta gtagaaatcg
     9121 attgttcttt accgtcccgg atcactagta cttctgattg ggaaacaatc gataatttcc
     9181 gtacaagatt tcttgcatgt atttcttgat aaattccaat aacgatattg acgacaataa
     9241 ttgctaaata cgccatgttg gaatacgcac ctacaaataa cagacaaatc ccaataccaa
     9301 agttcagaaa attgaataac gtcaatatat tatcgctgaa tatttgtttt gtactttttg
     9361 atgcatcttc ctggtagtca ttttgctggc cagaagccat tttctgaact acctcttgct
     9421 gtgtaagtcc attcattttc tttttctcca ttttccgcca actttcaaaa ataatcacgt
     9481 gtttaagtct agcgtgttcc aagattaaaa acaacttgtt tttataaaat ttatagaaaa
     9541 acacacgaat gattttacaa aaaagatgcc aacctttttg tttgaatcac ccgtgtgctg
     9601 tttttattat caatctatct ttacttatat tgttcctcca aacggctcat ccaccaacct
     9661 agtgctgtac cggctataaa aagaacagga caagctagta ccccagcaac tcccaatccc
     9721 gcgtaatcgg taggaatgat cataatcgtt gaagcaaaaa ctacacctaa aatgaaatgg
     9781 aatagcttgc tatatgcctt tgagaaaatg taatccatga tttttgacaa tccaagaaca
     9841 caaagaatcc caccaattcc gatcggcaca atcacttcaa gtcgtacttc tttaaatccg
     9901 tcagccatcg ctttatacaa tcccatatac accaaaaaat tagaagggct caatcctggg
     9961 acgatcatac ccaaaccaat caatccgccg gcaatcagcc atgttccaaa attctgatcg
    10021 acttgcccgt caaataattg agcgccgtat aataaaaaca aataagccag aacaaaagta
    10081 acaaccatga tgatcacatc agaagtatct cttccttttt tccctgcttc tttccataac
    10141 gcaggaacag ttccagcgat acatccgaca aaaaaccata atatcgttgt ttcatacgca
    10201 cctaataaaa aactgactaa aaaagaaagt agaaagatgc ctgtcactcc gcctagacca
    10261 acaggcagaa aaaacaaaac attttctttg aaattttttg taaggtgggc taaaaaagaa
    10321 atcagccgct catacatgcc aaagacagct gctaatgcac caccgctgac tcctggcaag
    10381 ataaatcctg aaccgataaa cattcccttc acaaaccgta acatccagtc tttggttgtg
    10441 taccccactt cttgattttc cattttttgc cttttttcca ctatttgcgt actccttctt
    10501 tcatttaatt ttattcatga ttgaacattt cctgctattt tacttaaaga ctttttcata
    10561 ggtctctatt attttttcat tcattttgac aatatcagga taaaacatgt tacctccatt
    10621 atgatagaga tagccgccat tgtaaagcaa ggactggatc cgccaatatc ggtattgttt
    10681 cccttcctca tttcctaaaa gtgggctcag cacatcttta gaatacgctt ctgctaattc
    10741 tactgtgttt tctccgccat gattttttac ataggcaata taatctttcc caaaattata
    10801 tgcttggaca gctgtccata aatcgcatcc ttgtttcttt gcttctacta tcatttccgc
    10861 caaatatttg acaccttgat caatactgtc agctggatta tcaatgatct cagcttctcc
    10921 atgcagactt tccgagctct gcatgagatc tgtccctttt ccttttgatt cggtcaatat
    10981 tatcgccttg atcaaattct cgtagttttc catatgataa ttttttgcag ctgttgttat
    11041 ttctatttga tagctttcca ctcgttttac cgaacgataa gttcttcctc ataaaaacaa
    11101 caccgcacca ataaccgtca gaatgatcat gtaaaaaaga atacggataa tagataatcg
    11161 ttttcgcttc atttcatcac ctagttattt tgacatcttt ttttatctta ctatttcttt
    11221 atcttcttgg ctatttcttc cttgatttct gtgtacgcct taagaaaaaa tgaattttcc
    11281 tgtatttttt gacatcttac gaaaatgatc gttgtttttc agtaaaaaca attgcccaat
    11341 gactgatata atcgttatac tttacacagt aggtgattat gtgaaaaaag aaaagaaata
    11401 tgcaaaaatg ccagatggga gcgaaattta ctatgaaaag agcggtcaag gcttccctct
    11461 ctttttactg catggcaatg acggcagcgg ccgctttttt tcagaacagg tccctgtact
    11521 cgaacgctac tataccgtgt atctagtaga tagccgagga catggtcgtt cgacaaacga
    11581 agcatctatg ttgaattttc agttaatggc cgaggatctg aatacgatca tgttgctgga
    11641 aaaaatcgat caggcagatt ttcttggatt tagtgatgga gcaaatctag cactggtatt
    11701 tgccagcagc ttccctaaaa aagttcatcg attgatttta aattctggaa acacgcttgt
    11761 taaaggcgtt cgtttttctg ccagagtcat cagtaatatt cattatgcat gggtatggtt
    11821 actctcttta tttcgcccaa gtcttcgcaa aaatctttta gttatcaaac ttttgctgca
    11881 tgacatcggg cttacagaaa atgatttaaa aaaaatcaac tcccccactt tgatcatcgt
    11941 gggaaaaaaa gatgtaatca agctaaaaca ttctttgtat atagctaaaa ctataccaaa
    12001 agcttccttt gtgcttgtga aagaacaagg acatgaatta gctagaaaag atcctgaacg
    12061 cttcaatcga gaagttcttc aatttctttc tgaaacataa ctattaggaa tagaaggtga
    12121 tttatttgtt aaaaaatacc atacaatggc tgaaaaacca cctaggactg ttcaaaacaa
    12181 tctttttgat ttctgtcatt gtcattattg tcggtgaatt gatgtccatc ggtaaaactc
    12241 tatctatcca gcaattagga gaaacgtttg ccactatacc tgtatggaaa agcggactaa
    12301 tgctattgat tggtcttatc tctgtgttac ctatggttgg ttatgatatt attttgaatc
    12361 ggatgcttga acaaaagcag aatcctcgtt acctgtttga gacaagctgg ctgatcaata
    12421 cgatcaacaa tattgccggt ttcggcgggt ttgttagtgt ggggcttcgc tctgaactat
    12481 atggacaaaa gaaagagagc agaaacgtga tccaagcatt atcgaaagtt ttcttgtttt
    12541 tgatggctgg actttctatt tacagtctgc tttctttttt acttgtagtc ttcacgccag
    12601 ttgctccttt tttgaagcaa tattggatat ggttgatcgg cggcggtcta tattttcctg
    12661 tcgtcttttt atttactact ttcaaaaaga aaggattcct tggtggtacc tcacttaaaa
    12721 ctcaaggaca gctattgcta gtttcattgt tggaatggac cggtgtcctg tttagtttcc
    12781 tttctgttgg ttatttaatg gaaatccgga ttgatctgtg gcaaacaatt ccattattca
    12841 ttgctgcttc agtgatagga atcgtgtcta tgattccagg agaaattggg agtttcgatg
    12901 taatgatgat tatcgggttg tccgctattg gtgtgccaag agaaatagtc gttgtgtgga
    12961 tcttgctcta tcgcctgttc tactacatca ttccgttttt gattggaatc gtctttttct
    13021 tcaaaaatat cggttccact tttgatcagc gttattctgg tatccctaaa caattagcaa
    13081 cagaaattgc gcataaaatc gtggttgtct tattatactt ttctggaatc atgctagtac
    13141 tttctgccac tatcccgcaa gcttttacag agtttcgctg gcttcatagt ttgaacccat
    13201 tgaaatttca ttttattatc caatttccta gtatactatt gggatttctt ttaatcatta
    13261 tgggcagagg gatcgcagca cgtgtgaaac gagcatattt gcctacaatc ttcttgattg
    13321 ttctagcttt actttatgtt ttattaagtg attttagttt cacaccggtg gttttcttgt
    13381 ctattctgct tctgatcatt cttgcttcta aaaacgaatt atttcgggaa caattgatct
    13441 attcatggga gtggcgtacg atcgatggaa tcattattgg tgcactgtcc ttgctttaca
    13501 tcgttattgg ggtatacaat ctgccggatt tccctcatcg gcgtcaccat tttatttcct
    13561 ttttcttatt tccttctgaa aagatttggt tttcgggatt gttggccatc atcgctgtta
    13621 gtttcatgat cgttctattt gttcatttcc ttcaaggaga aaagaaacag attggcgaag
    13681 cctttaatga agaaaaggcc ctgaagatcc ttacaactta tggaggaaac tccgatagtc
    13741 aattgatctt cttaaaagat aagcggatgt ttgcctatga aaaagacggt gaaccaactg
    13801 ttcttctcca attcgcttgc ttcaataata aatgtattgt aatgggtgat ccttctggta
    13861 agaaagaaga ttttccagaa gcaatcgaag cttttatcga agaaacagat cgactatgct
    13921 atttaccagt tttctacgaa acaagcgaag agattgttat gattttgcat gaattcggct
    13981 acgatttcat taagatgggg gaagaagctt atgtagacct gaatagtttt acaacttcag
    14041 ggaaaaaaat gaagggcact cgtgctgtct tgaatcggat cgaacgagaa ggatttacat
    14101 ttgatgtctt acaaccacca ttttctactg agcaaatgag tactttcaaa aatatctctg
    14161 ataattggtt gggttcacga aaggaaaaag ggttttcttt aggctttttc tctgaagatt
    14221 atctacaaag agcgcctatt gcagttgtca aaaataccca agaagaaatt gtcgcttttg
    14281 caacgatcat gcctacttac acgaacaata aagtaggaac gattgatctg atgcgatatg
    14341 attctaaaaa agcaccttct ggcagtatgg atttcttgtt cttgcatttg tttgcctata
    14401 tgaaagaaga acatatccaa tggttcaatt tagggatggc ccctctttca aatgtcggaa
    14461 cttccagaaa gagtttttta caggaaagga ttgcatactt ggtttacgag tttggttctc
    14521 atttttattc tttccatgga ttaagagaat ataaaagcaa gtacgctaca aactgggtct
    14581 cacgttatac tctatattct agagatagtt ggattgcata tgttatgatt gctttgctga
    14641 ttattgataa tgcgccagtt gagcagacac aaggtagaat aagtggtttg aaaaaatgga
    14701 tacgaagaaa gtattaaaaa ctgcataccg atagatgaac actctcatga tgaataaaag
    14761 agactgaagt aaaacgaaag ttcatgcttc tacaatctct tcttatacaa ttgaagaaca
    14821 aagagcggtc caaacagaaa tcctgtttgg accgctcttt tattttaaac atttttcatt
    14881 accaaaatat tcgagtcgcg tttcttatgc ttcgatctct gtaacgatac ctgaacctac
    14941 tgtccgtccg ccttcacgaa ttgagaatgt cgttccgttt tcaacagcga ttggatggat
    15001 caagtcaaca tcaatcgtca cgttgtcacc aggcatgacc atttctgtat cttctggcaa
    15061 tgtgattgtt cctgtaacat cagttgtgcg gaagtagaac tgtggacgat agttgttgaa
    15121 gaatggagta tgacgtccac cttcttcttt tgtcaacacg tacacttctg ctttgaattt
    15181 tgtatgtgga gtaatggaac ctggtttagc aagtacttgt ccacgttcga tatcgtcacg
    15241 ttggatcccc cgtaacaaca cgcctacgtt atccccagct tccccgtaat ctaacgtttt
    15301 acggaacatt tctacacctg ttacaactgc tttttgtgtt tcaggtttga tccctacgat
    15361 ctctacctca tcaccgacac gaacagcacc acgatcaata cgacctgagg caacagttcc
    15421 tcgacctgta attgagaaga cgtcttccac tggcaatagt aatggtttat ctgtatcacg
    15481 ttctggtgtt gggatatatt catctactgt atccatcaat tccataatag cagcttcagc
    15541 atctggatcg ccttgcaatg cttttaatgc ggaacctttg atcacaggag tgtcatcgcc
    15601 tgggaaacca tattcgctca ataactcgcg aacttccatt tctaccaaat cgatcaattc
    15661 ttcatcatcg actaaatcaa ctttgttcaa gaaaacaatc aggtatttta caccaacttg
    15721 gcgtgacaat aaaatgtgtt cacgtgtttg aggcatcgga ccgtcagttg cagaaacaac
    15781 taagattgca ccatccattt gtgctgcccc tgtaatcatg tttttcacat agtccgcgtg
    15841 tcctggtgca tcaatatgcg cgtagtggcg tttttctgtt tcatattcta cgtgtgcggt
    15901 attgatcgta atcccacgtt cacgttcttc tggagctgca tcaatactag catagtcttg
    15961 aggatttgct aggccttttt tgcctaatac tgtagtgatc gcagcagtta aagtagtttt
    16021 cccatggtca acgtgtccaa tcgtaccaat gttaacgtgt ggtttacttc tgtcataatg
    16081 ttcttttgcc ataatttaca aacctcctaa ataatataga tcactgaaaa atttcagctc
    16141 tcaccttttt attatagtct ttttttgact aaatcaaaaa gaatacgtcc gacttacttt
    16201 ttgtaagatt cgaactaagc ttattatacg tcaatattgg tcaaagtcaa ctaagagcac
    16261 tcgtctgtct tatacgcgaa aaaagtacct tttataaata aaaaaatgtg ttttttgaga
    16321 aaaacttcaa gatagtcctt aactttcttt tgaagcaata agaacaaaat gaggaaaagt
    16381 ttaaaattca gctgttgcca acaactttca atagacgaaa tcttctattt cgttaataat
    16441 aaggaaagag gtgaagtaca tgaaaaaatt aattggcgta cttgtcgttt taggcatatt
    16501 tctcggcgga agttttgcag cttatcatta tttttacggc ggcgaagctt attatacaaa
    16561 aatcacgacg aatggcgaaa tgtcagctac ccaagcagat aacggagaga aattcacgac
    16621 ttatacctac aagcaagcgg cttataataa agatggtgaa aaaaaacagg tgacgcttcg
    16681 cgaagaaaga gaacatccat taaagatgaa tgcgtatctt aaactcaaag tcaatcctcg
    16741 taaaggtgta ttaagctggg aagaaataaa ggcttctgaa gtgcctaaaa atgcggcaga
    16801 aaaaatcgat aattagtaaa tggtcttaaa attttattag ataaaaagag gctgggacag
    16861 aagcgtttaa ctccaagaaa taagaaggag ttgcttctgc ttccgccgtt tatacgtgtt
    16921 tagagcgtga gacaaaagtg ttctttactt ttgtctcacg ctcttttttt gttatattcg
    16981 tcttttccga tccttctctt gacacaattc atttaactga tcactggtac ttgaacacct
    17041 aatattctag tcatttttat aaacgattca atacttcatc cacatttttg atcatcacgg
    17101 atatcgtacc atccggatta ttcacaaatt caatcaaatc tgggttgcga tatacatcta
    17161 ctggtacgat cagttcgatc ccgtttgata gcttgaattt ttgttttcca aattttttct
    17221 cagaaatttc ttgtacttct tttacaggag gtgcttctgg gacaaatcct tgctcttgta
    17281 cttcttcttt aaaagccatt tttgccgtga tgttttcctt gaagactttt tccgcaatca
    17341 tctcatgatc caaccgacct ttttcttcta tcgtatcata gacagcttct ttcaaatcag
    17401 ccatgatatc aaattcttct gtctcaaatt tttttccaag atgcttggct actttttgga
    17461 tcacttttac attttcttct aaagaaggtg caggaacact ttcgatcact cttccagaaa
    17521 aataaagctc ttttttgcca gaaaactcat attttttttc aattaattcg taggtccaat
    17581 cagtcaaatt cacagcgaat gcttcatctg ctttttgtgt tttcgcccct agaattgctc
    17641 gattcaaaat caagcggttg tcgatccctg cttcgtctgc ttcaacaaag tgagtgtaag
    17701 cctcacgata attgactttc aataaagata agtacatcac tgtatctaat tcatacaaga
    17761 caacaaatac atctgcacta ggtgcttctt cactttcttg gtagatatcg aaccaccgct
    17821 gaacgattgc ttcacttgct tccacaaaat tttcttgagc gattttaagt gattcaacga
    17881 tcatgctttc ttctgctagt tgtccagttt ttgtttgagc agaagagatt ttttggatct
    17941 tcttttgaag aaaatcacga atatattctt ttgtcagatc cagctctttt tgtgaaaaga
    18001 ctggagaacc agtttctctg tcaataatat gcagaattgc tttttttaaa tagatatcca
    18061 ttttctcatt cccttctgtc ttagtttacg gaaaaaaaat caaaaatacc agaatcaaaa
    18121 tcattttctt ttaaacaaaa atttcaagag tagaaacaaa atggattctt tttttcgaaa
    18181 aatgcgctac acttatagtt gaacgaataa aaaaggagct gaaagtatga attcattaac
    18241 aagcacttat cgtctatcaa atggttacga aatcccggta gtaggattcg gcacatggca
    18301 aacacctgat ggggatgtcg ctgtttcctc tgttaaagaa gcgctggctg caggttatcg
    18361 ccatatcgat actgcccaag gatacaagaa tgaagaaagc gtcggccaag cgattaagga
    18421 aagtggaatt cctagagaag agatattctt gacaacaaaa ttatggaatg caaaccacag
    18481 ctatgaactt gtgatgtctt cttttgaaga atcattgaag aagctccaaa cagattattt
    18541 agatctgttt ttgatccact ggccaaaccc tgttgctttt cgtgataatt gggaacaagc
    18601 aaatgcagat acatggcgag catttgaaga actgtatgaa gcaggtaaaa tcaaagcaat
    18661 cggtgtgagc aatttcttac cccaccatct agatacacta gcaaaaacag caaaaattat
    18721 gccgatggtc aatcaagttt tccttgcacc aggcgaatta cagacaactg tagttgagta
    18781 tgcaaaaaaa catgatatga tcctcgaagc atatagtcca ttaggcactg gtaaaatctt
    18841 cgatgtgcct gaaatgaaac aaatcgctga agcacatgac aagacgattg cacaagttgc
    18901 tttgcgttgg tcgctgcaac acgaattcct tcctcttcct aagtcagtga caccaagcag
    18961 aatcaaagaa aatactgaat tatttgattt tgaattaaca gaagaagaaa tgaaacaaat
    19021 cgatcagtta gatggtgtag tcggcaaagc aaaagaccca gatactaccc aattttaagt
    19081 cgaaaggtga ttttatggat ccaatcgaac gcttgaattc tctctcggaa gaagttaccc
    19141 agacttttca ttccgatttt gtctttttga tcgatgcaga gaaaatccaa cattttcctg
    19201 caagaaactg gacacatgat caaatcatcg aagaactgaa aaaacggttc gatcattcgc
    19261 taatggtcaa accctggcac gaacatgaag tcatttattc acctgaacta cctgtttttg
    19321 ccttgatacc gaaaaaatag aaagaatgga acggattatg tatatataca taatccgttc
    19381 cattttttat ttttctttca aaaaacggga aaatacgcaa atttttctgt tgtaatttgc
    19441 gtatacgcaa gtttttttgc attactcctt ttcatttggc tgtttttttc ttataatcga
    19501 aagggtatga gcgaaggaga gaacatatga agaaaaaaca gaaacaaaaa ttattaaatc
    19561 aattccgtcc ttcattggat ggtgtaagag gacaattatt ccgttctcta gaagaagaga
    19621 gcttgcgacg ttatggtttg ccgttacaag tcatgcttga tcccaaaaac cgtcaaatct
    19681 taacgatcgg attagctggg aaaacaaatg aagatacacg gatcaacgtg ccaatcgatg
    19741 acaacttcaa tactgtatta aagagaattc gttcaggaga aaacgggatt ttcgaacgat
    19801 tccgtgacaa tcttcttatt gaaatcgtgt cttactggaa tgatcaacga ttgaaaaacg
    19861 atgaaccaac tgcgcaagct gttgcgacac cagttacaga agaaacagtc agtgtgccag
    19921 aagaaaaaac ggaaaaacca aaagcggaca caactgaaaa tacacgctca actgatacga
    19981 atgccgcttt aagttttgct gatttttcaa aagccgttgc tgagtatcct aaattttaca
    20041 cagaacaaaa tgaacatgaa gtagttatta atgaaaaaaa tgctgatgaa cctcgtaaat
    20101 tagcaactat ttctatgact actgaaaatg agttcgttat cgaaaaagca ctcgaacgga
    20161 aatacaaagt caaattgact ttgattcctt tgatcgaaca atttgcagcg acagcgatta
    20221 ctgatcgata aaaattctat ttgtcataaa aggctgggat ttaaaatccc agccttttta
    20281 gtcatataat aatttctaca gcaagtaaaa agaaattcct tctaacatca ggctcaaata
    20341 tcagcttgac ctgtccaaca aatcacctat gatcctacaa tgttaggcga cttctcttct
    20401 acctgaagat atcttggagt tgcctgattt cttaagatgc ctaaccttaa ctataaaaaa
    20461 ttctaataat aaacatattt tctgatagag aaaaaag
//
LOCUS       DAFENC010000048        20367 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.050, whole genome shotgun sequence.
ACCESSION   DAFENC010000048
VERSION     DAFENC010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20367
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.050"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..1350
                     /locus_tag="LP493_002262"
     CDS             <1..1350
                     /locus_tag="LP493_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBL2134384.1"
                     /translation="TNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDT
                     VKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNLPALPEGTTVTDVTPGGT
                     IDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNPEGQKVTTDLNKEPDA
                     SEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSDEVEVDVTVTDTRSD
                     ADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGTVVVT
                     YPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLPDGSQHHG
                     TADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNKKDSGKNGSKGSKTD
                     NQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTLGLLGYKNRKKENE"
     gene            1484..2815
                     /locus_tag="LP493_002263"
     CDS             1484..2815
                     /locus_tag="LP493_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL2134385.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFIFSFVKLS"
     gene            complement(2802..3761)
                     /locus_tag="LP493_002264"
     CDS             complement(2802..3761)
                     /locus_tag="LP493_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL2134386.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFLSYVTKDDLSNLI"
     gene            4005..5408
                     /locus_tag="LP493_002265"
     CDS             4005..5408
                     /locus_tag="LP493_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HBL2134387.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTISS
                     TESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFSTPQQIESTESFQSQPI
                     LSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIAQAILESASGQSQLAQA
                     PNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYENYEESFEDYAKLLTKGI
                     SGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNELIKTYDLTNYDKEVKGP
                     QMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIHAVKAGKVVKAEFHYSW
                     GNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGSTGNSTGPHLHLEICKDS
                     SLSQSMLVDPKTLLFGD"
     gene            5757..6389
                     /locus_tag="LP493_002266"
     CDS             5757..6389
                     /locus_tag="LP493_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HBL2134388.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLTGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            6977..8416
                     /locus_tag="LP493_002267"
     CDS             6977..8416
                     /locus_tag="LP493_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2134389.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            8711..8929
                     /locus_tag="LP493_002268"
                     /pseudo
     CDS             8711..8929
                     /locus_tag="LP493_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251366.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            9178..9393
                     /locus_tag="LP493_002269"
     CDS             9178..9393
                     /locus_tag="LP493_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134390.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(9610..9866)
                     /locus_tag="LP493_002270"
                     /pseudo
     CDS             complement(9610..9866)
                     /locus_tag="LP493_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(10053..10964)
                     /locus_tag="LP493_002271"
     CDS             complement(10053..10964)
                     /locus_tag="LP493_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL2134391.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(10983..11987)
                     /locus_tag="LP493_002272"
     CDS             complement(10983..11987)
                     /locus_tag="LP493_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBL2134392.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(11984..14107)
                     /locus_tag="LP493_002273"
     CDS             complement(11984..14107)
                     /locus_tag="LP493_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBL2134393.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(14112..15032)
                     /locus_tag="LP493_002274"
     CDS             complement(14112..15032)
                     /locus_tag="LP493_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL2134394.1"
                     /translation="MPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILT
                     FLTGISSRDGEKFPVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTD
                     YDFAHLLFSDGSITQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVIS
                     TFALDFIHSNREIFKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDD
                     LLDERLKNNIGLKFAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLY
                     GRVGVVQVHPVFEELFHAFDTRPPVQERME"
     gene            complement(15166..16992)
                     /gene="ltrA"
                     /locus_tag="LP493_002275"
     CDS             complement(15166..16992)
                     /gene="ltrA"
                     /locus_tag="LP493_002275"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBL2134395.1"
                     /translation="MLKKNKLRYNEYYDMQHIYDELYAQSKNGNNFYKLLEIIGSEQN
                     ICLAYRNLKSNSGSKTAGTDGMTIDDIKQLSNAEIVATVRESLSNYRPKSVRRVFIPK
                     AGSDKMRPLGIPCIWDRLVQQCILQVLEPICEPKFHNHSYGFRANRSAHHAVSRVTTL
                     INLSKYHYCVDVDIKGFFDNVNHGKLLKQIWTLGIRDKRLICIISKMLKAEIDGEGVP
                     EKGTPQGGLLSPLLSLIVLNELDWWVSSQWETFQPKNRSKNGWLQYAKKYTKLKSGFI
                     VRYADDFKIMCSTYGEAQRFYHSTVDFLNKRLKLEISPEKSKVVNLKKNSSDFLGFKI
                     KVIPKGRTKHGYVAKTDMNQKALKKAKTNLKLKVKDIARHTTGFNISRYNLTVIGMQN
                     YYCIATNVYNNLTEVSYALLPTIRIRLRNIAKSVPFESTSSEFQSRTKGIRPKTKIVM
                     IADNPLLPIQGVQHKNPMNFSQDICNFTKQGRNKVHEDVVVVTKEEIRALLENENPAD
                     SVEFNDNRISAYIAQQGNCYVMNRRGTPSTLICIHKSDKGDNLDRYSNLAFVEIPIAK
                     AILTESADEAKSLLKGYVLNSQQKKKLNRIRTNYGYQTITGK"
     gene            complement(17692..19239)
                     /locus_tag="LP493_002276"
                     /pseudo
     CDS             complement(17692..19239)
                     /locus_tag="LP493_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346907.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            complement(19226..19615)
                     /locus_tag="LP493_002277"
     CDS             complement(19226..19615)
                     /locus_tag="LP493_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL2134396.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(19675..20178)
                     /locus_tag="LP493_002278"
     CDS             complement(19675..20178)
                     /locus_tag="LP493_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBL2134397.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(20191..20352)
                     /locus_tag="LP493_002279"
     CDS             complement(20191..20352)
                     /locus_tag="LP493_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134398.1"
                     /translation="MAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGVKDVLL
                     SLFNRIVGA"
BASE COUNT         6315 a         3887 c         3722 g         6443 t
ORIGIN      
        1 actaacttgc cagcgttacc agaaggaaca acagtaacag atgttactcc cggcggtaca
       61 attgatacca acacaccagg taattacgaa ggtgtcattg aagtaacgta tccagacggt
      121 acgaaagata cggtgaaagt tccagtagaa gtgacagaca atcgttctga cgccgataaa
      181 tatgaaccaa cagtagaagg cgaaaaagta gaaattggag gcacagtaga tttaacagat
      241 aatgttacta acttgccagc gttaccagaa ggaacaacag taacagatgt tactcccggc
      301 ggtacaattg ataccaacac accaggcaat tatgaaggtg tcattgaagt aacgtatcca
      361 gacggtacga aagatacggt gaaagttcca gtagaagtga cagacaatcg ttctaatgca
      421 gataaataca atcctgaagg acaaaaagtg actacagact taaataaaga gccagatgca
      481 tctgagggaa ttaagaacaa agaagattta ccaaaaggaa ctacttatgc ttggaaagag
      541 aaagtagatg ttagcacagc tggaaataaa aaaggtacta ttgtagtgac atatccagat
      601 ggatcatctg atgaagttga agtagacgtt acagtgacag atactcgttc cgatgcagat
      661 aaatataatc ctgaaggaca aaaagtgact acagacttaa ataaagagcc agatgcatct
      721 gagggaatta agaacaaaga agatctacca aaaggaacta cttatacttg gaaagaaaaa
      781 gtagatgtta gtacagctgg aaacaaaaaa ggtactgtag tagtaacata tccagatgga
      841 tctaaagaag aagtagaagt tactatttct gtagtagata aaaaagcacc gaataaacct
      901 caagttgatc ctattacaga gggtgaccaa attgttactg gtaaaactga accaaatgca
      961 gaggtgacag ttacattacc agacggaagt caacaccatg ggacagctga taaaaatggt
     1021 aattttacag ttaaagttcc taaattagag gcagggacaa aagtgatagt aactgcaact
     1081 gatgaatctg gtaatactag tgaacctact aatgtagttg tttcttccaa caaaaaagac
     1141 agtggaaaaa acggtagtaa aggtagtaag actgacaatc aaggtagcaa cagcaatcaa
     1201 gacaaaaata gaggcaaaag ccagtcctca aaagtttttc ctaagacggg agagagtgac
     1261 agtaatatct ttactattag cggtggttta atactgttag gaacgttagg attattaggg
     1321 tataaaaatc gaaaaaaaga gaatgaatag aaaatcaatt tcttaagtct tctctgagaa
     1381 gaggaagaat ctttttcttc ctctttttgc ttttttatga tgggaaataa gtgttagtta
     1441 aagatgaata tactttttat agaaaggaaa agaatgtaat taagtggaaa aaatagtaat
     1501 tattggttca aaccattcag ggctagccgc agctcgattt ctaaacttaa gcgattcaaa
     1561 ttatgaagtt attctaatcg ataaaaaatc agaaattagt tacttggaat gtgggacatc
     1621 gttatttata aaaggagaag taagtaattt agaagatctt ttttatcaaa atagaatgac
     1681 actaaattct gagataaaaa agttatttct agagacagaa gttgacaaaa ttgatattca
     1741 aaataaaaag attagttgtg taaaaaaaga tggtacaaga ttctctcaag aatatgacaa
     1801 agttatatta gctacaggtt caaagcaaat tatgctagat ataccgggga ataatttagc
     1861 taatattttt tcgataaaga attttccaaa tgcaaaagag atttttaaag ctttggatga
     1921 tagtactatt aaaaaagtag gaattattgg agcaggatat attggagttg aaattgctga
     1981 agccataaga aaaagaggga aagaagtata tcttttcgat gttgcagata gagtgttgtc
     2041 gacttattac gaccgtagtt tttcagataa agttgaagaa atactatcaa aaaatggaat
     2101 acatctttgt ctatcagaaa gtcctaaaaa atatttagga agaaaaaaga ttgaaaaaat
     2161 agtcactaca agtggtaccc aatactctat ggatatggtc gtacaagcta taggatttct
     2221 atctaatagt ccaattgggg aaaaggaact cttgagagat gttagtggag catatctaac
     2281 taatgaatac cagcaaacaa atataaaaga tatatatgct attggggatt gtgctacaac
     2341 tttttttacg tccattaata gaagtagtgt tgatttttct atttctaatg ctctaagaac
     2401 agcttatatt gcaactcaac atattaacaa tcaagatttt acaccttctg gttcccaatt
     2461 tacaaatggc ttttctatat ttaattacaa tttttacgca gcaggtttga atttaaaaac
     2521 agcacgatta ttaagtgagt ctatagatta tatagaaata gaagatttca ttagacctgc
     2581 ttttttgaga aaaaatagtc gtgtaaaatt aagaattagc tttgaaaaaa atacaaagag
     2641 aatagtaggt gtacaacttt gtagtcaaga agatttatct ggactattat caatgttttc
     2701 tcttgctata gaagaacaaa ttacattaga caaattgaaa atgttagatt atttatttca
     2761 tcctagtttt agccaaccct ataattttat tttttcgttt gtcaaattaa gttagacaaa
     2821 tcatcttttg tgacgtaact caaaaatact tccattggtg tccgatagtg taatgatttt
     2881 ctaggaatat gatttcgttt cgatgccacc gattggataa aggtttcaga tacaccatta
     2941 aaatccatag ctttatacaa accatcttta cgtaataagc catttgaatg ttcattcaat
     3001 cctcgttgag aaggtgttcc tggatccgca aaataaattg aaatatcgtt ggtattacta
     3061 atctttttcc aatttgagaa ttcttttcca caatcaaatg tgatggattt aaataagttt
     3121 tttgggacac aacgaaacca ttgattcagc ctattttcaa tgtctttagc ctgtctgcct
     3181 tcgggtttca aggtaatgat gactttagat agccgttcaa ctaatgtgat gaccgcgctt
     3241 ttatgttttc cacccacgat agtgtcacct tccaggtgac caaattcatg atcaaactgg
     3301 gtatagtctg tctttctgtc tcggattgac cggcgaaacc cttgttttcc tcttttttct
     3361 ttatgaccgt ttggttttct ttttcccttc attggtaaat cgtgagtgtc aaaggtttta
     3421 tctttaaaca ttcgatacag tgtgcgtacc gaacaagcaa taggaaactc tgctcgacca
     3481 ataaggacat caggagccca cccttgaaca accttttttt gaatgtattc ctgttgctca
     3541 tcaggtaaaa caatcggatg tcttccgcag ttacgtttgt ttttcttata ttgtttatag
     3601 tagctcattg cgcttccacc agatttaaga aaacgataga ccttataaat agtttgtcga
     3661 gaacgttgta acagattggc tacttttgaa acaggttgtg attgattgaa ataagcttct
     3721 atcattacga gttcagttgg tgtaagatgg ttataggtca tttgtactca ctccttataa
     3781 ttctttcgtc ggaactattt tgagtgtagc acaaatgact ttttttagtt gtctagctta
     3841 attttacaat cggcgtttta aaggcagtaa caggattaaa cattgaaaca taatcgttac
     3901 taaatgaaat caagaaatat actgtattac tcaattcatt gaaaatattt atcataattt
     3961 ttaatagaaa acactattaa agagaaaaaa gagaggtaaa tcaaatgaaa aaatctttaa
     4021 aacttgcatc agcagttata ttaatgtccc aactccttat agcaacacct ttccatgtgt
     4081 tggcaagcga aaattcaaca tacaaaattg caaaagaaag aaccgagacg actgaaatga
     4141 gtaattccga tgtaacagca gagagtagtg aacttttgac aacttcatca agtgaaagta
     4201 gtacgacttc aaatgccgag tcttcaacaa cttcatcaag tgaaagtagt acgacttcaa
     4261 atgccgagtc ttcaacaact tcgtcaagtg aaagtagtac gatttcaagt accgaatctt
     4321 caacaacttc aagtagtaca agtgaaataa cttcttcgaa agtgacaaaa ccaaaccata
     4381 tagaatcttc aaaaaaggaa gcgccaaaaa cggaaggaca aacaaaaact ttttcgacac
     4441 cacagcaaat agaatcaaca gaatctttcc aatcacaacc aatactatct ggtaatgaag
     4501 aaattcattt tgacaaaaat gaatctgtag aaaattttat tatgaaaatt ggtgagtctg
     4561 cgagaaaaat tggtcagaaa tatgatttat atgcttctgt tatgattgca caagcgatct
     4621 tagaatctgc cagtggtcaa agccagttag ctcaggcacc gaattacaat ttatttggga
     4681 taaaaggaac ttataatgga aactttgtca ttatggtaac aaacgaagat ttgggtaatg
     4741 gaacgcttta tacgacccaa tcaaaattta gagtgtatga aaactatgag gaaagctttg
     4801 aagattatgc caaattatta actaagggaa ttagtggaaa taaagatttt tatgcaggag
     4861 cattaaaagc taatagtaaa acatatcgag aagcaactaa attccttaca ggacggtatg
     4921 caacagatac acaatactat ttgaagctaa atgaattaat taaaacctac gatttaacca
     4981 actatgataa agaagttaaa ggtccacaaa tgagtaagac tggataccaa gtgcctattc
     5041 ataattattc aataaccagt ttgtttggaa atcgtggaaa tgaatttcac cgaggacttg
     5101 atatggcagc tacacagggt gagccgattc atgcagttaa agctggtaag gttgttaaag
     5161 cagagtttca ctactcttgg ggaaattacg tggtgataca acacgaagat ggatcaaccg
     5221 cgttatatgc tcaccagcaa caatacctag taaaaactgg agataatgtt ttgcaaggac
     5281 aaataattgg ctatgtagga agtactggga atagtactgg cccacacctt catttggaaa
     5341 tttgcaaaga tagtagtctt tctcagagca tgttagttga tccgaaaacc ttattattcg
     5401 gagactaaaa aaggtaatca atctgacaaa gtaacaagaa aatggttgga ttcttagacc
     5461 tttgatcagg atattgagac tggaattgat atctcgatta cgatgggttt gacaaataaa
     5521 acaagtccat tatcgaatat cgagtgtatt attgccgtct ttatgctcat attttgagca
     5581 ggtttcacta gatgaaaaca atttatctat cttgaggatt tcgtgtacgt atcgttcagt
     5641 cttgtattgt aaattagtca taaaatcaga ctaagaaaaa ttggaaatat ttttttctga
     5701 tttattaaaa gttaattgaa attatatggt acttctttct tgggagggta ggtgcagtga
     5761 aggaaagata tggtcacctt actgttgttg aggagattac tcataatgga tataaaaaat
     5821 atcgttgcct atgtgactgt gggaatgaaa cgattgtata tcgatcaaac ttactaacag
     5881 gtagaaccaa aagttgtgga tgtggaaatt ataaaaatag gcataaatat aaaaatttga
     5941 caaataaaac ttttggtaag ttagttgcaa tcaagccaac taaactgcga agtgaaggaa
     6001 ctgttgtttg ggaatgtcaa tgtctgtgtg ggagaaaaaa gttagtatcg gcaaagcgac
     6061 ttctaaaagg tgatgtaaaa agctgtggat gtttgaaatc aaaaaagcat cacattgaaa
     6121 ataaaaaatt cggattactt actgcaaagt atcctttgga caataactgt tcatggaaaa
     6181 caaaatgggt ttgtcattgt gagtgtggca gtatgtgtga gataagttat agtaacttat
     6241 tttttggaca tactcaaagt tgtggatgtt taaaaaggca agaaacaagg acatgtgttg
     6301 aagggacagt aatagagtgt ctaacgtcaa aattaccgaa aaataataca agtggtgtta
     6361 agggagttta tcgttctaaa gagaaataga ttgcgtatat aactttaaaa aaaaagaggt
     6421 actatttagg atcgtatgat tctattaaga gtgcagctca agctagaaaa gatgctgaaa
     6481 ataaattgtt tcaacctttg attgacaaat atcgaggtaa tcattaatta ttgtggataa
     6541 taattaacag tgatatataa acatctataa tatattattc atactattga tatttagtat
     6601 aatcctatgg aattgaatat catagcaatg tatttgaaaa gcaaattgga aaacaaatag
     6661 gtgcaacacc ataaatatga aaaaattggg aaaaagtaga atggaaattt gcttacgtct
     6721 cacgagatag ctcacactat taatctgaag aacaatgaag tcgactttta gaaattgcta
     6781 gaagaaagta aagcgaatta tcactagtta ctatagagta agttcaaata aagcatctcc
     6841 aacttacatg gttacatgag gatatcaaat cgaaattact caagcttcct atggctagag
     6901 tcgcgagaag ttgttgggca gtagacatag gttatattgt tcttagctac acgatcatta
     6961 gaaaggaaat cctattatgt atagttatca agaagatgca aaagtccaaa aaaatcgctg
     7021 gtggattttg attgctatat ctatgtttac cttcatgtcc acattggatg gcagtattgt
     7081 caatattgca ctacctacca tctcagatga tatgggcata ccaatgaatc aagcggaatg
     7141 ggtagtgtcc gtttatctga tgattgtctg ttcttgtttg ttgctgtttg gtaaaattgg
     7201 cgatagccgt gggaaaatca aagtatttcg gattggtacg ctgatctttg tcttgggatc
     7261 gctgttgtgt gggttcaatc attcgctagg tattttattg ttcgcacggg tggtacaagc
     7321 cattggtgct agtatgacta tggctacaaa tgccggaatc atcacggaag tctttcccat
     7381 acatgaacgt ggtcgggcat tgggagcaat aggtgcgttt gtttcattag gctcgattgc
     7441 tggaccaggt cttggcggct tgattttgtc ccaattttct tgggcgtaca ttttttggat
     7501 caatgtaccg gtgggaatcg taacgatgtt gattgctgaa aaattcttac caaaagatat
     7561 caccatgagc ggccatacaa tcgatggagg gggctttgct gccattgcgg ctacgattat
     7621 cagctttttt ggagcaatct ttttggggca agaaagtggc tttttccatc cagtccccct
     7681 tgtactgttc gtaatttcag tgattgcctt tgtcagcttt ttaaaagttg aaaagaaagc
     7741 agcctctcca ttgatttctt tcggtatttt taagaacaag atttttacca tgagcttgat
     7801 tacagccttg ttgatttttt cttccaactt ctttgtcaat gtagtgattc ctttttatct
     7861 gcaaaatgct cgcgggttga gtcctagcta tgctgggctg ttgatgatgg tctttccttt
     7921 gatgatggtc gtcggggcgc ctttaagcgg ctacctgacc gaccgggttg gcccggagat
     7981 tttggtatta gtaggcttgg gcttattgtc ggtaacccag gtcatgtata tgtttttgtc
     8041 agtggactct cctttgtggc tatacattgt cgctactgcc atcatgggtg ccggcaatgc
     8101 cttgttccag tcccccaata atacgatggt tatgagctcg gtcactatcg aaaacttggg
     8161 actggcaggc tcgatgaatt cctttgcccg aaatttgggg atggtcagcg ggatttcgct
     8221 ttctacgacg gtcttatatc aagcgatgtc tgctaagatg ggccagcaag taactaacta
     8281 tatcgcaaat cggccggatg tctttttata tggaatgaag attacctttt taggcagctt
     8341 tgttttgtgt tttgttgcct ttttcctgac tatctggcgt atcaaaaaac aaggaggtat
     8401 tcagaaaaat gtctgaaaaa accactgttg aagaattttt ggaggcctgc gtatgggtga
     8461 gtgggatttc catggatgat ggaagatgaa gtgaacttct aaaagccgaa aaactcaagt
     8521 attatcttca aaatactagt gctcaatgag atgcttgatt tgatcacaag aagactgcga
     8581 aagccgctgg caaccgcaag ctaggtatcc caccgatgga ctacgtttta gaggctactg
     8641 gttatgaata cggagccaac gctctcatct gcataagaat acatcaccca gattatgtaa
     8701 agattttcga tacttctgtc aaaaaatcat taagatagat aaatgatttc cgtctagtca
     8761 aattggttca gaatgtagac acacagatgg taagaagtca ctcacaattc gagaatggac
     8821 ttgtcctatt tgccgtatac atcataatcg aaacgtcaac gatagtatca atattttgac
     8881 caagggctat gaatacaagc attgccttag aaaacatcaa gaaccttagg aacaacgggg
     8941 atagcttggt taataagaga taccgctgtt taggcttgca agtatactct tttatcaaga
     9001 attccgtggc tttagtcatg agaggcttaa tactatgaaa attttcttta gcatttttga
     9061 tttaggttcc ttttctaatt ataataagat gaccactaca gtaacctact gaaatatata
     9121 aacagccact gtagtaccat tttcaaagta gtctatgaga ggagaatctt cattcttatg
     9181 aacgctggaa ttgcggatat gaatttaata aaaaaaaccc ttaatgattt tacttccaat
     9241 tcaatatcaa aaggtactgg tatcaattta agcacaataa aaaagctgaa aagtggtgaa
     9301 agatcagtgg aaaagctgaa tcttttagat gctataaaaa taacggaatt tgctatgaaa
     9361 aatggaaaag ctgagattga aatatggaga taattatcgt ctagtgaatt acttgccact
     9421 tagctgaatt taacgatcct tggtgcttga agggggagat tcttgggaat agagcatact
     9481 tgcaagccta tgtctttact aacaacgata tctcttatta accaagctat ccccgtagtt
     9541 ctaaggcttt tacttttatc taagcaataa tcgtattcaa aggaaatttt tgacccttag
     9601 aaagtctcat tttatcagac gtgagcttag gcattgctga attttgttaa ttcggtttta
     9661 ggttgtgctt tgagcataat atgaaagtat tctttatcac gatttcattc atctaaggta
     9721 atgtgatgtg attctgaaat tctttcaaag gcagtttttg cataagctga cattacatca
     9781 tcaatgacat gtttacaatg tttcactact aaaataaggg ggtaaccaag aagaaaaact
     9841 gaatgattat ttgtatctaa ttccatggta tatcaaccat ttcctatata gactgattat
     9901 gacatggatt aaaataaaaa ggcactatgt cttaattgtc ggttttcgag ttaccgaatg
     9961 gcattcatca cccacctata gaggatgggc gacttctgcc tgaaataagt tacactactt
    10021 ataacttcta ataaaattag attgagtcat tattatttaa catcaacgat tttccagttt
    10081 ccattttttt gtaatactaa tttgtactga aagtagctag tggtttttga tacattatca
    10141 aggtatttta tctttgtact cactagaaaa ttttttccgt tttgtagata aactggattc
    10201 tctaactccg aaaactttaa gtcaatattg attggtcgca tcgcaccatt ttcaacataa
    10261 tactccaatt ctttttcaga agctgatgga taaagtttaa aaaatgtttc taaaaaatcg
    10321 gtgatttctt ccgttgtttt ggcatcaatt tctgaatcgt tttctacttg ttttgcttca
    10381 tattttgcct tgtctggctt tccaatcatt gttggcaaac tagttactaa atgattcctg
    10441 ttttcatctt caaagattgt cactcgatat gcagaagaaa ttgattgcgt cttttttccc
    10501 tctgtaatat gttgctccac taaaaatgaa acgacaaatt cttccgagtg tttttcaaca
    10561 tctagaattt ttacagattg aacttcggaa ctcgtgggaa tatctgctcg aaccatatct
    10621 tggattaaag cgagaccgtt ttctgtaagg tactgttcga gattactcat tctcttttca
    10681 attgcttctt tgttattttt ccatgaaaaa tattctttcg caaaatcctc tgtaaaactt
    10741 tcaacgccag aagtattcac taccttctct tttataacca ctttttcatg agttgtatgt
    10801 tgatcaatgg cggtgaaatt tttataaacg ccaaaagcaa gactacaaga caataaaagc
    10861 caaagggcaa gcaccatttt tcgatgctta cccacggata caactcgttc ttttttcttt
    10921 tttgggctct tttccttttg attccgttca atttttatct tcattctttt tcctcttttc
    10981 tcttatttgt atcggccagc tccgataaga tgctgccgcc aatagttttc cgttagattc
    11041 gtccacccca ctggatctcc tgcatgaaac atgcgattct cccctgcgta aatgcccaca
    11101 tgggtcacat aagtaccggc atcataggtt gaatgaaaga aaactaaatc acctggtttg
    11161 gcatctttta gatcaatatg agtcatggca tcatattgat cctgagccac ccgaggaagt
    11221 ttcaggtcaa ctttggcata acaccattgg gtcaagccac tacaatcaaa ccccgtttct
    11281 ggacttgagc caccaaacac ataggccgtt ccttcatact taaatgcctc atcaaaaatt
    11341 tcttggacta ttttgtcatc aaactgagtt gtagttaggt attgcttcac taataaacag
    11401 taaaacatat tgccataatt ataccgccac ccaccatttt ccttaatcgc gattgggttg
    11461 gggtaatcga ctttttgacc acctgatttt tcctttgaaa aagattcagc taaagcaaaa
    11521 ctatgcttct tcccgttttt cccgacatga tctagatacc cgccaccata gttataggcc
    11581 tgaataatac tatcttgatc acaccctagt tctttggaac gcttaaccaa agacgcaaaa
    11641 tagagacagc cttgtttgat ggatgcctcg gtacttaatg aattaggtgg taatccggct
    11701 gactcagaac tttgcataac gtcttccatt gtgccaccag attccacttg aataatcgcc
    11761 aaaagaattg gaatatactc tgttatatcc gattctttgg catacttttc caccattgca
    11821 cggtgtttca atacttcttc tgagacacta gttccgccag gagaagtgcc agaactacca
    11881 tttccctcac tgtcttcacc aaacaacaaa cccacacaca tcaaaatacc cataaaagag
    11941 atggtcagaa aagttaatga aataacaccc actttcttca agttcatttt ttctcacctg
    12001 accttgattt tggacgatgg ttcattcttt tttgtacttt ttgattggtc tgctttggca
    12061 gagtggacct ctgtttcact tgttggaaag aatttttctt acttgctgat tggcttttcc
    12121 cttttgaaat gatttcttga ctagttagtt ttcgtttgat ttcgggattc agatttgctc
    12181 tcacaatccg ctttggtgct tcttttttca gcatcatatc tttctgaggt tgagctgctt
    12241 tatctattgg aatattcgcc cttctttttc cctgacgatt tgttgcttca ctcagtatct
    12301 tgcgtttttc gtccattttc gcatttcttc gttgtcgttg tttttctcgc aaatccactc
    12361 gatccgcttt ttcttggaac agtccgcgct tgaattcttc tggtgctttt ttcgactttt
    12421 cgattccttt atggagattg tatttcaaat tcgttggcgt attccttacc tgatccttta
    12481 cttgtttagt cttatctttc accaaagctt gggtatccaa aactttgccg atttttctcc
    12541 cagccaaatt cattcgggat tgtttcttat tatttgaaac tggattctcc ttagttaagt
    12601 cagatagtat ttcgtgatcg ttcggtaatc gtgaattctt tcgtagagaa gaaccggatg
    12661 gcttaaattt ggattttgat tgttcctttg ccaacttatt tccgactgct gcaccaccac
    12721 caaaagccaa agctcgtccc acatttcgat tgagttgccg caattttcga ttcattaaca
    12781 tttgcggttt tcgcatgacg cgtcttccca ttgactggct atcattactc tggaggttga
    12841 acatactcat aatgtcgccc aatttgaaat agataccggc aaaggtcaca atttgcagaa
    12901 aagcaaccat gaaaaatgga taggttgccg aaatattgaa aaacatcgtg gagatgctaa
    12961 atgcagtcgt aatcaccaaa gtaacacccg ctcgcatcat aatcgtattg aataaacgaa
    13021 taatcgcctt ctttcctaaa ctttcataag tcggcaacat ggacaataag aaactaattg
    13081 gcagaaacat cgcaaagata atgaagagaa tttgcgagaa caacataatc cctgttagaa
    13141 gaaaaacaaa gaaggaaatg ccaatattga acaataccaa aaagaccacg gtccctaaac
    13201 ggttcatggt cttggtaata ctgagattcg cattgtcatt gtcttcaatc tctgccttga
    13261 ccgcttcttc ccgatctttg cctttgtttt catctggact cacagataga atcttgttga
    13321 cccggtcttc accaatttct tctatgttgg aatcatcaaa ttgcagtagt aaccaaggtt
    13381 gttggacttg aatcgaaaac aaactatccc gaatcaaatc cacactatct tttccttggc
    13441 tttctgaatt gggtacaacg atctcggttc caagggtaag ggccgcttca ctaacatctg
    13501 agctaaagtc attgattttt gtgatatagg taggcgcata agcaatgaac gaacccgata
    13561 gtagaaaaat catcacaaaa ttaatcacgg ctcgaactgc tttcgtggtt tctcgtttta
    13621 ataatccggt atacgccaca tacaccccca gagctaaaat catcaataat agaaacccaa
    13681 aataaaatcc ggaggtctgg agtccatttt cagtaatacc agccaatgtt tggatattct
    13741 ttccaatact ttcagccgta tccgaaatga aatctaattt gtaagcctct tgaaccacat
    13801 aacccgtggc gttcgacaaa tacaaactca ccgtccaaat gaaattagta atggcataaa
    13861 gaccatacat cacgcttttc cctaagccat caccccaatt ccaaggcaac caatcccaag
    13921 agctatccac aaagaaatct agttgatagt tgttcagtga atatttggaa tatagatttc
    13981 ctgcttcaac tgtatcatca actagccctg tcgcctcggc taccgtacca actaaactca
    14041 atagaactat cagagtgagt atgctaataa aaacgattcc cacaatccga aaaagtttct
    14101 ttttcatccc ctcactccat tctctcttga acaggtggac gggtatcaaa ggcatggaag
    14161 agttcttcaa agactggatg tacctgaacc acgcctaccc gaccatacaa atcctgcatc
    14221 aagcattggc cattttccaa atctcgtagg cgtttttgat tgctttcatc ttctcgatcc
    14281 aagccaaaga attccaaggt tttcttgatt tcatgaatat cggtactgcg aaacgcaaac
    14341 ttcaacccga tattattctt caagcgttca tccagtaaat catcactatt ttgcgtgaca
    14401 aagtaaaccc cggcattcat agcccgccca gcacgaacga gcttattcga taatgttttc
    14461 ccttgcgcta cttgaagaaa actccacgcc tcatctaagt ctacaatttt gaagatttct
    14521 cgattactat ggataaagtc caaggcaaaa gtggaaatga cgattagcat ggaaacacta
    14581 agcaattcca tggtggtata ttcttcaaaa gtggtttctg catctggtaa aaccaaatcc
    14641 gctacttgaa tgatatttaa ctgcctatct aaactaatcg actgggtaat cgaaccatct
    14701 gagaaaagca aatgggcaaa atcataatcg gtaaaggact cgatgtgatc cgcgatattt
    14761 tccgcaactg gtgagccttc ttttcgaagc tcattaatta cttgtaataa tccccgttga
    14821 ttgctttggg taaccgtccg aatggcctta cgcaacactg gaaacttctc cccatctcga
    14881 ctagaaattc ctgttaaaaa ggtcagaata tcaattgcta gactttcaga atccttcttt
    14941 ttctccataa tcacataagg atcaagtaat ccttgatttt ttggcttact agttaagttg
    15001 agaatattga tttcatccgc aatttctggc aaggtttctt tccagccacc ccgttatagc
    15061 gataggtaac tttttgatgt tatctccaag ttttcccccg cttcacaccg tacatgaaac
    15121 tttcgcttca tacggcgttc catcatatcc aaatagattt ataagttatt tcccagttat
    15181 tgtctggtat ccgtaattcg tccgtattct gttcagtttt ttcttctgct gactattaag
    15241 aacataacct tttaacagtg attttgcttc gtctgctgat tctgttagga ttgcctttgc
    15301 aatgggaatt tccacaaatg ccagattaga atatctgtca aggttatctc ctttgtctga
    15361 tttgtgaata catatcagag tggacggagt tcctcgacga ttcattacat agcagttgcc
    15421 ttgttgtgcg atatatgccg aaatacgatt gtcgttaaac tctacgctat cggcagggtt
    15481 ttcattttcc aacaacgctc ggatttcttc ttttgttaca actacaacgt cctcatgcac
    15541 cttgtttctc ccttgctttg taaaattaca aatatcttgc gagaaattca taggattttt
    15601 gtgttgtact ccttgaatcg gcaatagcgg attatccgca atcatcacta tttttgtttt
    15661 tggtctgatt ccttttgtcc tgctctgaaa ttctgaactt gtactttcaa atggaactga
    15721 ttttgcaatg ttccttaaac ggattcgtat ggtcggtaag agagcgtaac ttacttctgt
    15781 caggttgtta tatacgttag ttgctatgca gtagtaattc tgcataccga taactgtcag
    15841 attatatctg ctgatattga agccagtcgt atgtctggct atatctttta cctttaactt
    15901 tagatttgtt ttcgctttct ttaatgcttt ttggttcata tctgttttgg caacataacc
    15961 gtgtttcgtt cttccttttg gaatgacttt gattttgaac cccagaaaat ctgatgaatt
    16021 tttcttcaga tttactacct ttgatttctc tggactgatt tctaatttca gccttttatt
    16081 aagaaaatct acggtactgt ggtaaaatct ttgtgcttct ccataggttg aacacatgat
    16141 tttaaaatca tcagcgtaac gtacaataaa accgcttttc agtttggtat atttctttgc
    16201 gtattgaagc cacccatttt tactgcggtt cttcggctgg aatgtttccc actgactgct
    16261 tacccaccag tctaattcat taaggactat gagggagagc agtggactta acagaccgcc
    16321 ttgtggcgtt cctttttctg ggacaccctc gccgtcaatt tcggctttca gcattttgct
    16381 gataatgcaa atcaatcttt tatcccgaat accaagtgtc cagatttgtt ttaatagttt
    16441 tccatgattg acattatcga aaaatccttt aatgtctacg tcaacacagt aatgatattt
    16501 tgataaattt atcagtgtcg ttactctgct gactgcatgg tgggcacttc gattcgcacg
    16561 gaatccatag gaatgattat ggaactttgg ttcgcatatc ggctctagga cttgcaggat
    16621 acattgttgt accagcctgt cccagataca cggaatcccc aatggacgca ttttatcgct
    16681 cccagctttt ggaatgaaaa cacgtctgac tgatttgggg cggtagttgc taaggctttc
    16741 ccgaacggta gcaacaatct cagcattgct gagttgtttt atatcgtcta tcgtcattcc
    16801 atccgttcca gccgttttac tgccactgtt tgatttcaga ttacggtaag ctaaacaaat
    16861 attttgttcc gaaccaataa tttcaagtaa cttataaaag ttattaccgt tcttgctctg
    16921 tgcgtataac tcgtcataaa tatgttgcat atcataatac tcgttatagc ggagcttgtt
    16981 tttctttagc atggtctgta ccctccttgt ttgcaggagc aagtacatct cttagtctta
    17041 ctcgaaccca taccattttt cttagtaatt ctattcttca tatgactagt ggctatccct
    17101 ccaccgcttg ttatcacggt ttcataggta ctgtgccacc actctcactg acattaacac
    17161 accttatatc attgctaatc tcacaataac tttctgatgt gaacacttca cagacagtaa
    17221 aatctccatg ttgtcagctt tcaacgttcc aaacacacta tctgtacata tatccttagg
    17281 tttcctctat aagcctgcta ccttgataac gcctttaacg ttatatggat tttcataaat
    17341 gcggagtctt actcacccac agtagcgaca ctgtttgtgt cactggacat ttctatccag
    17401 ccccgatata gacctgtaca ttcaaggatt cgtcagtaga cctctcatct acattctaac
    17461 catagatatt ttatagactt ccggcatata ggacacaacg cccacctctg ggaatctttc
    17521 gtcagcatta tctgttacgg tgtctgtctg ccgacttcac cgagcttctg acagagcctt
    17581 gtttactcaa gtttctgcca gtcagagtat taaagtagcc tttcagggcg ttaccccgtc
    17641 attcgactat tcgtgtgttt agttctccaa cacacattaa atattgattt aatgaagtgc
    17701 tgtgcctact cttttcaagt aggaacgttt cgcaccccct tttggatcga caatcacagc
    17761 ttgtccacca aaaaggacgg cgtaataaac taagagattg ttactaaagg actttccgcc
    17821 accgagtgaa ccgaggaatg ccgctgctag cgcattggta actgaatcct tgaccccttg
    17881 tgaggccaat gccggtttca ggtaaacatt gcgccccgta tctacgttat aaccaaagta
    17941 aatgccttcc aactccccta acatctgagt ggcgccaaaa ccaagtccgg cgagaaaatc
    18001 agacgtaaca tactggatat aatcattcat gtatcgctta ctagaaggta agaattcttc
    18061 atgtagcccc atcatatcgc caaaaggccg gactagtttt acattggtat catcataaaa
    18121 atctagcact tcatcacacc ggcgctttag ttcatctact gattcggcac ttactcgaac
    18181 cacatagctc agtttgtaca tggattcttt ggactgatcc aaggtagttt ccaattcatc
    18241 tacggaatcc aatgcatcta agacattgga atttgtttca ttgtcagatt gataggcatg
    18301 gttgtccaag tcttttaatt cctttttctt attgcgaacg gtagcaagtg cctttttgtt
    18361 cgtcacaatc tccacattca tactagtgtc aattgggaat gtaaattgtt gttgctggta
    18421 atagaaaagt tctgaggagg gaaactccat ttcccccaca attgtattaa ttgttaagta
    18481 cgctacatat gattcatgat tctcatgttc catgcataag taccggggct tttcttcaat
    18541 caaacaacga ctgggacgta ataagtcgta acgtttcacc aaagtttccg acttcagctt
    18601 tttctttggt agctgaaatt catattcttc aaatggtgta cccttttcgc catagatatg
    18661 ttcaatcaaa tacatcagat cactcggtgt gactcgtctg actttaaatc ttcgagccaa
    18721 tttactttcc attagttttt caagcttggt atatcggcga atttcttcat tggataagga
    18781 aacaaaatcg cccatcaaat gatgattcac tccatagaca aattcttgaa agccggagaa
    18841 gaaagatttc ttgagattct ttagattgac ctcttcatct gtcgcaatca gtttgaagcc
    18901 aataaaaaag cgataatcaa tctgactatc gccaatcatg gatactaatg cctctgtctg
    18961 taaatcaatt cgttgtttcg ctacttctgt taatcgcccg gtaatttcct tttttgatcg
    19021 ttcttgcgtg gcacgaatac tactttctgt ggcaatttgt aaggcatgaa tcttgccttc
    19081 acgattttgc gcaatcaatt gacgaaagtt atcgtggact tgatatttct gttcaggtga
    19141 caaaaaggag taattgtaag gtattaactc atagtaggca aaacattctc cctcttgatt
    19201 aaagacaaga ttattttcaa tatacttaat cgggtacata gttcacactc cttaccagag
    19261 taatgggttc gtcccatcgt ttcttctgtt ctttgacttt ctttcctgcg aaagtgacct
    19321 taaatcgtaa gtgatagcta ataaaagatc gtaaaaatcc caatggtttc ttaccgtcaa
    19381 acgttttttg cgacatgaac caagtaactg ccaccggtat acctaagtat tttaaaaagg
    19441 ccccctctat catagatagt ggaggcacat gggcaaatac gatgacaaac agcaaggata
    19501 aaacaaacca agccatctgg ttaaaagtca caggaaaagg cagttgaaag tcattaattg
    19561 cataaatgac cttttcaact gcccaaatac tggtgtagct ttttattttc ttcatcaaat
    19621 cattccttta aaaagaagga tagtttagaa atcaactacc cttcaataat tttgttaata
    19681 tggatactca aaaacacctc gactcgttac caaataattg cctccaatct ccaagtctct
    19741 accacacgca tcaaaatcaa tatacgtctt caagtgttct ggtacttctc caaaatcacc
    19801 agcttctaca atcaagaaat atgctacatc actcatatca tcgcaatctg gataatagat
    19861 aatatcatcc acatgctcta ccatctcctc aaaagaattg aagaaagcat gttgaatctc
    19921 agaagcaact tcaccaactg gcgttccttc aagttcctcc gctaagccac acaaccgatt
    19981 aatttcctca attggcgtat actcatcaat ctcaaaggga agttcataat catgaattgc
    20041 atattcctcg tattcgtcat ttaacccaat tcgttctttc acttcatcaa aatcgacagg
    20101 tggggtaaac cacgccccca ccaattcacc ttcgttatat ttcccgaggt tcgcaatata
    20161 aacacgcatc tgttccatcg tgcttccccc ttacgcaccg acaattcggt taaacaaact
    20221 gagtaagaca tccttcaccc cagaagcatt aaagaccaat ccgaccgcaa tcaaagcaat
    20281 caccaaaaag ccaatcagtt tggaaaactc ccgcttaaat cctaaaaaca aaccaatgac
    20341 cacaattgcc agtaagacta aggattg
//
LOCUS       DAFENC010000049        19682 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.051, whole genome shotgun sequence.
ACCESSION   DAFENC010000049
VERSION     DAFENC010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19682
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.051"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            311..1090
                     /locus_tag="LP493_002280"
     CDS             311..1090
                     /locus_tag="LP493_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134399.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKIFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVIIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADIQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTVLSQIEQIRNEKISAAYATKAQTVAEQMGYSNISY"
     gene            1136..2080
                     /locus_tag="LP493_002281"
     CDS             1136..2080
                     /locus_tag="LP493_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBL2134400.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDYGRQGR
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMNFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            2096..2875
                     /locus_tag="LP493_002282"
     CDS             2096..2875
                     /locus_tag="LP493_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HBL2134401.1"
                     /translation="MEETISLKEIFETLRKHLVIIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     EQIKDAISVNQAENSQMFSIQAISTNAVAAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLMTGLMLGMMVGVGLAFLLELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGPAQTQPKATNDKTAPSRRSRSRV"
     gene            2887..3585
                     /locus_tag="LP493_002283"
     CDS             2887..3585
                     /locus_tag="LP493_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HBL2134402.1"
                     /translation="MARTQKQKAAQTHAVSLVTLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVIYKTFKLNNAS
                     GLSTVLSSSGSVADEIQRTPVDNLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLTKAKELLDMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            3613..4377
                     /locus_tag="LP493_002284"
     CDS             3613..4377
                     /locus_tag="LP493_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HBL2134403.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKIPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKEFG
                     KEKVVQMKQVAKDLINGDEINYPIYEEVKKKKFGLF"
     gene            4421..5872
                     /locus_tag="LP493_002285"
     CDS             4421..5872
                     /locus_tag="LP493_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBL2134404.1"
                     /translation="MYRKNSSGWSKHIDFILLDLFCVQLAFYISYVMRQGDWNPYVIP
                     IYRHMAIFIELENLTIIFLFEAYKNVLKRGYYKEAVASIKQSFMLLLVCSLYLITMQD
                     GNDYSRVSLFIMGVVYGLLTYIIRILWKGLLHHRMKNGEDVSLVIVTSQKIAKNVVRN
                     LKEKNYGMYKLSGVIVVDRDMYGTTIGGVPVVANADNAAEYLLQNWVDEVFINVDESV
                     PYPKELIARCSEMGLAVHMNLTKVSDSTRGKQFIGRVGDYTVITSSINVMTMRQAFIK
                     RTIDILAGIIGCIATGVIFIFVAPVIYIKSPGPIFFAQERIGQNGKTFKMYKFRSMYM
                     DAEERKAELMKENKMSNNLMFKMDFDPRIIGNKILPDGTKKTGIGQFIRSTSLDEFPQ
                     FYNVLMGKMSLVGFRPCLKSEYEKYDFHHRARIAMKPGITGMWQVSGRSDITDFEEVV
                     KLDAEYIRNWSMGLDFRILFRTVKTVLHRNGSM"
     gene            5904..7040
                     /locus_tag="LP493_002286"
     CDS             5904..7040
                     /locus_tag="LP493_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBL2134405.1"
                     /translation="MARKKLKICMLGHKRIPSREGGIEIVVEELATRMVALGHEVTCY
                     NRSGHHVSGKEFDQHKNKEYKGVKLKTIFTLNIKGIAAMSSSVFGGIRAAFGKYDIVH
                     FHAEGPCAMLWLPKLFGKRCVATIHGLDHQREKWNKLASTYIMLGEKCAVKFADEIIV
                     LSESVQNYFEDIYGRKTRFIPNGVKKIEIKSAGLITEKYGLTKDSYILFLGRLVPEKG
                     IRYLIEAFKDVQTDKKLIIAGGSSDTDEFANELKELAKGDERIIFTGFVQGQELEELY
                     SNAYIYTLPSDLEGMPLSLLEAMSYGNCCIVSNISECTEVVEDKAMIFKKSDVSDLKI
                     RLEEACNQSEMVKVLKNQATEFICSKYNWDKIVQETLNLYRGNI"
     gene            7040..8146
                     /locus_tag="LP493_002287"
     CDS             7040..8146
                     /locus_tag="LP493_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HBL2134406.1"
                     /translation="MIRILQCVNDMHRAGLETMLMNYYRNIDRTKIQFDFLTHRPYKS
                     DYDEEIISLGGKVYYAPRLYPQNYPKYFKWMEQFFKDHPEYEIVHSHIDAMSYLPLKA
                     AKKAGIPIRIAHSHNTSIDRDFKYLLKQYYRCKLTSVLTHEFSCGKVAGDFLFRNDKF
                     TLIPNAVDAKKFYYDESIRNDVRMKLGISSQTFVMGHIGRISYSKNHRFLIEIFKEFH
                     AIKNNSVLLIIGTGDMEEEIKNYAKKSGIDDDIKFLGNRNDIEKFYQAFDVLMLPSLF
                     EGVPLVGIEAQFADLPCFFSEKVPTEVAFSDKTNFISLNQSAKEWAREIANVDISHRD
                     SERSILIKADYNIQTAYKILESKYYELFELIQRG"
     gene            8152..9174
                     /locus_tag="LP493_002288"
     CDS             8152..9174
                     /locus_tag="LP493_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide synthesis protein"
                     /protein_id="HBL2134407.1"
                     /translation="MTQKHSSIKRIIHRISEELNATRRIAKITSWKEAFATLQAKIDI
                     QVMNRNGYNESKKQKEHLLKKHEVMLKYYEKTFSDFLKTYDYSQNQIINQSKSPYSNC
                     IWVCWWQGLDQSPEIVKACVKSIKRNAGKHTVIILTEDNYRQYVDIPKWVEEKKNKGI
                     ITRTNYSDLLRLSLLAKHGGLWLDATFYCTKPIPDEYFDIDIWSIRRPDYAHASVASG
                     YFAGYSLACNQESRWMFAIIRDFFLNYWKNNDMMVDYLMIDYMIVLAQRINHEIAQTF
                     DKIPSNNPLCDELIKNLNNIYDEKVWNLLKKDTLLFKLTWKQSFKKQKDDKVTFYGML
                     VENKLL"
     gene            9196..10251
                     /locus_tag="LP493_002289"
     CDS             9196..10251
                     /locus_tag="LP493_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBL2134408.1"
                     /translation="MKHKVSVIVPIYNVEKYLRKCVDSLLSQTLKEIEIVLVDDGSPD
                     ASGEIADEYQKKYSNVKTIHRENGGLGPARNTGIENATGEYVAFLDSDDWVESDMYEK
                     LYLVASKENADIVVSGHCDFANDKAMVKKQHPLSGNVYDTPNSIKNVRKNLFGHSPKD
                     QEVEAFPMSVCMSLYNKNLLDKYRLRFEKILSEDTIFNLNAYDVANKIAFTEYTDYCY
                     RKEEQESITKSLSPNKQTEFKEFLITLKAIASKEDLECQIRAKRMAIDYCRLYVGLVD
                     DANLGIKEKRKYIKKFIEDEGLIQCWKGYPTNTLPFQQKFFHKMLECKCYTILLLLSR
                     IRKIIKNMTRKKLFIIL"
     gene            10869..12104
                     /locus_tag="LP493_002290"
     CDS             10869..12104
                     /locus_tag="LP493_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134409.1"
                     /translation="MSVKKMLFMVSTIIVLTSRFWGINTSLSMRYFIMAIWDLYFMLS
                     YFSYREKTYKKYVIKNNFWLTIMPFVIFSIYTLIIWGIGSNAEFENFIKLCSTLLYLI
                     LAYGYACTAFYLFKAEGIDFIFWSGVISYMSGSVFYLIVSYGLNGLISYIKSLITGET
                     NTANFAMEVHDLTFAMGVFFLYYVFFENKNTKKHKIKIIVSLILIFMGLKRIELLALS
                     GAILVYYVLLKWGKKIQIRALVCTICATVISLVFIYIIDTGILALLMSNLGITDDGAR
                     LSFYLYSSKFYELGLGYVGTGWTWFSKYFFNLYLSHFRLNGGRIAASLHSDILTIYIE
                     VGCIVFIIWMFWLFFVKPIRLTKKFGLKTGECVLLLTIYMFILYLTDNTLTYPDTQMI
                     FLLVPMIVSWVDNQQRISE"
     gene            12188..13276
                     /locus_tag="LP493_002291"
     CDS             12188..13276
                     /locus_tag="LP493_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134410.1"
                     /translation="MKKILVLANTYYQIIVAIQMKNTIFSDEYVEIIISDHSKNTKEI
                     AKKIEEKKVFDGCHYLESKSFDDNIGYFQKIKDCLQISCGKSNRYAYYLKNCKSEYFD
                     EFICFSMGEVWLEGIYACLYRNNKNVQVSILEEGILSYGVDIIPTARTKAIAVLNYLK
                     KRTPLYNKSYNFYCFFPNIYTGRENTIQIPLVTAGSRTALQLSDIFNPMIDIYKEKKY
                     IFFTSVYDFEGGEPVGEYELVCKIADLVGKDNLIVKTHPRDVRTIYKDNGFIEDKNSS
                     IPWEAIQLSGDFNDKIFMTINSGSVISGSTMSAKPVRTYYMYKLCNIEGNPSCKKNAY
                     DIERLLKQKTMKNILKNVKIAESLDDIL"
     gene            13273..14694
                     /locus_tag="LP493_002292"
     CDS             13273..14694
                     /locus_tag="LP493_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBL2134411.1"
                     /translation="MSKTKYLIKNMGILTISNFSSKILVFLLVPLYTSVLSTTEYGTY
                     DLTISTATLLFPILTLNIVDAVMRFLMDKDKNKKNIASIAIKVIFLSVIVFGSVMYLL
                     NITKLWQDVYGLEKYIFLYYISYVWNQFLIQFAKGLEKVKAMGIAGIISTIVTIIANI
                     FFLLILKWGLIGFFIANILSQIISATYLSVLVRIWEYIDFEAKDPQLKREMLNYSIPL
                     IATVVGWWINSTADRYVVSFIVGVSANGLLSVAYKIPQIINTLQGIFIQAWQISAIKE
                     YGDNETAKFYGNTFVMINLLMCITCSSLIILTRPFSHILYAKDFYEAWKYVPFLLIAN
                     VLNCASGLLGPILSAKKDSKSMMWSAIIGALVNVIMSVVLVYKIGVQGATIATVICSY
                     VIYVVRKRAVGKDIFIKHYHIVVESWGLLFVQAIIEIYFKNYVIEIIIMIILIIINIS
                     YIKQLCYRGRNIISMIKSREHKR"
     gene            14730..15446
                     /locus_tag="LP493_002293"
     CDS             14730..15446
                     /locus_tag="LP493_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HBL2134412.1"
                     /translation="MVDNYERKNILKKKSIGCRMKIVAIVPMKLNNKRLPQKNTKAFT
                     NGKPLCYYILSTLLKVKQIDKVYVYCSNPDIKEFIPEGVTFLKRSSSLDQDTTSITQV
                     LAGFTKEVEADVYVMTHTTAPFISEKSIEKGLDAVLTGEYDSAFAAKKLQDFLWKDGE
                     PFNYELDNIPRTQDLPPLYEETSGFYIYNRNVMTELHRRIGKKPCIVEVGEIESVDID
                     EAEDFMIADAIYNHLILQGS"
     gene            15465..17048
                     /locus_tag="LP493_002294"
     CDS             15465..17048
                     /locus_tag="LP493_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase catalytic domain-containing protein"
                     /protein_id="HBL2134413.1"
                     /translation="MNNVQILDCTLRDGGYCNNWEFGFDNTKKIISGLIESGIEIIEC
                     GFLTNKTVYNKNVTKYTTLEELAQIIPEKREGKLFVAMMNYGEYNIEDLPDYDGSSID
                     GIRIAFHKKNCNEALKLCREIKKKGYLVFVQAMVSLNYTDEEFLAVIKNVNQFKPYAF
                     YIVDSFGMMKGKDLTRLFYMIEHNLEKDIQIGFHSHNNMQLAYSNAQKLITVQTNRSL
                     IIDSSVYGMGRGAGNLNTELFVEYLNDNAGKKYQLKPLLYIIDEILNSFYQKSYWGYS
                     LPNYISAVHNAHPNYASYLSYKNTLTIEAMNEIFEMMDEEKKVSYDKQYIEDLYYKYM
                     ETGKIQEEYMEELRKFLSDKKILLIAPGKSSVDEVERIKEFVTKEEVVIISVNFEYSH
                     IDIDYVFLSNLRRFHELPKESRTKCIVTSNIQASDVYLRTSYKKLLSEREVVRDNAGL
                     MAIRFLADMNVDEIFLAGFDGYSHNEDENYGEQSMEIITKFALLDAMNVQMRDELSEL
                     AKKVKVTFLTDPRWVRIDK"
     gene            17183..17761
                     /locus_tag="LP493_002295"
     CDS             17183..17761
                     /locus_tag="LP493_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134414.1"
                     /translation="MISILCIVAYHANLRLNYNADGIIVHGSLTANQIFLNYIGIWGQ
                     LGVNCFIFISAYFLSEKRNIHFENVLGIVLECIFYSVLVYGILCACGIETFSLNSFVK
                     EILSFALGRYWFITSYLALYILSPYLNIMLNNLEKLQLQKISMLLFIGVCCYRMLFKT
                     SLFGDCAVLIALYVICYTLKKTIIIFLRDTES"
     gene            17707..18225
                     /locus_tag="LP493_002296"
     CDS             17707..18225
                     /locus_tag="LP493_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134415.1"
                     /translation="MLYTEKNDNNIFERHRIIGTIVCITVIPLLISIGILFKFIPNAM
                     VNQMVHIGSPLMVIASIFLFYVFKNFSFYSKYINKLARTSLGVYILHENHYFIDGMKS
                     RGLIWDGIFGLGKRFLDRDFWIWFIIAVVVVCIICMAIDVVREKFERQIFKIKSVKNL
                     CKLMNHVINIYP"
     gene            18233..19273
                     /locus_tag="LP493_002297"
     CDS             18233..19273
                     /locus_tag="LP493_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBL2134416.1"
                     /translation="MRRKEVKVISFGELLLRLAAPGYSKLFQRDSLETTFCGGEANVA
                     VSLAIFGYQSEFITKLPDSDVGYAAANALRYFGVNVDNIIFGEGRMGLYYLEKGAAQR
                     PSKVIYDRKFSAISLADSDEFKWKEILNDANWFHWTGINPALSENLFETSLDACQAAK
                     KRGITISCDLNYRSKLWTSEEAKEKMEQILPLVDICICNEEDAEKVLGIKAEHTNINS
                     GELNKDGYVQVAREIHKKFGCRYVATTLRRSYSASRNGWSAMLYEAEKDKAYFSTEYN
                     IQIVDRVGGGDSFSAGIIYALCENMSGQKAIEFATASSCLKHTIEGDFNRTTIEDVYN
                     LMNSGGNGRVLR"
     gene            19522..>19682
                     /locus_tag="LP493_002298"
     CDS             19522..>19682
                     /locus_tag="LP493_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL2134417.1"
                     /translation="MTYTYLTTDELVIIESYLKINQSVAKTAHCLNRSSQTIHKVYLF
                     FKQRKSALE"
BASE COUNT         7180 a         2484 c         3842 g         6176 t
ORIGIN      
        1 tattattaat tcaatgttaa tttttttgtt attctatttt ttgtgtaact tttaaaaaca
       61 cctatgaaaa ttatggaaat aaaaatgaaa tcgattaatt tttatcttat taatgtttta
      121 tttactttta aatcgtaaat tgccctagtc aagaaaacag tttgtggtat gattatatag
      181 ggaaaacttg tttacaaata tttctgtgaa tatattagtt taattatgtt tttttaaata
      241 aaaagctgtc atttttatgt aagtgaatta tatcttaatt tatctatcat caatacttag
      301 gagtgaatct atggaaaagc cattcgtcaa gtcattgact gctgtggcgg taggtgcagg
      361 tgctattgcg atctgtttgt ttggatacca tatcaataat cagcggcaac atcagcaacg
      421 gatcaattat gcagaatctg ccatcaccaa tcaaaaagac accttgactt ctttatcaaa
      481 agaagtagac aagctgtata gtacaaaaga aaaaattttt ctaaaccctg aaataacaga
      541 agaaacaatc acaagtttgt caaataagct atcctctgtc aaactttcag cagatgatta
      601 cgacatcaaa gaatcagaat tgcctaaaga agctgttgca atccaagatg agaagaaagc
      661 aatcgtgaca cagttagata gtgcagaatc aaaactgaag atccagacag ctgtcaacga
      721 tttatttact aaaaatgtat caaactggca gcaagctgta gacgatgtca tcatcaaaga
      781 aaaggtgaca agtgcagatg tcgctcgtgt acgtgaaaat atgagctttt ttaaagatag
      841 tccttggaaa acggttgtta tgcaatatct aggattcgct gatattcaga tcgcgcaagt
      901 cacgcaacta gatcagttat tcgatacgat gttaaaggat ggtcaagtga ctgccaccgc
      961 tacttacgat caatatttga cggtgctcag tcaaatagag cagatccgga atgaaaaaat
     1021 aagcgcagca tacgcaacaa aagcacaaac tgttgctgag caaatgggct atagcaatat
     1081 aagctattga cagttaaaac gttgattcaa gcaaggttag caaacggagg aaactatggc
     1141 aagacgaaga agaaaatcaa gagggaaaaa aatatttctg attattttag cagttcttat
     1201 cgtattagta ttagcaattg taggagtagg agcaaaatta tatctggatc tctcacattc
     1261 tattgagaaa acttacgaat cagtggaacg aacccaagga gaacgaacga aaccagttga
     1321 tctggacaaa caagaatctt tctctgttct attgatgggg attgatactg gagatttagg
     1381 tcgggtcgat caaggaagat cagatacgat gatggttgcc acagtcagtc ctgaagacaa
     1441 acagacaacg atcgtcagca ttcctcgtga tacgtatgtc gacatcgtag gtcgtgacac
     1501 aaaagacaag atcaaccacg cttacgcatt cggcggagct gccatggcga tggataccgt
     1561 acaaaaatat gtagacatcc caatcgatca ctatgtctct atcaatatga aagggctaaa
     1621 ggaactcgtt gatgcagttg gtggtatcga agtcaataat gacctcactt tctcacaaga
     1681 tggctatgac tttccaatcg gtaaaattac attgaacggg gatcaggcat tatcttattc
     1741 tcgtatgcgt tatgaagacc caaatggtga ttacggtaga caagggcgcc aaagaaagat
     1801 cgtagaaggc gtagcgaaaa aagtattgag tctaaacggt gtcagcaact atcaatccgt
     1861 tttgaatgct ctagagtcga atatgaaaac agacatgaac tttgatgaaa tgaaaaaaat
     1921 tgctttagat tatcgggagg catttggtac gattaagcaa gatcagctgc aaggagaagg
     1981 cttcatgcaa gataatatct cctatcaaaa agtcagtgat caagaacttg atcgtgtgaa
     2041 aaaagaatta aaagatcaaa tgaatctaga gaataaatag gaaagtggag aaaaaatgga
     2101 agagacaatc agcttgaaag aaatttttga aacattacgc aaacacttgg taataatcat
     2161 catctcaatg tttgctggct tggccatctc aggaatcgta acatttttca tcttgacacc
     2221 aaaatacagt tcacaagcac aattgatcgt gacactgcca caatcagaca ctgcaaatgt
     2281 caatgatgtc aatacgaacc tgcaaatgat caatacgtat aaagatatga tcgtcagtga
     2341 tttagtgctc aatgaagtca aagatcgttt agaaacagaa gacaatgtga aaatgactgc
     2401 tgaacaaatc aaagatgcca tctcagttaa tcaggcagaa aattcacaaa tgttctcgat
     2461 tcaggcaata agtacgaatg cagtggctgc tcaacagatc gctaacacaa cttcacaagt
     2521 tttccaagag aacgcaaaag atgtgatgaa tgttgataaa atctcgatca tttcaggtgc
     2581 agttgccaat acgacacctg tttcgccaaa taataaattg aatttaatga ctggcttaat
     2641 gttaggaatg atggtaggtg taggtctggc attcttattg gaattactcg atcggacagt
     2701 gaaagatgaa aaatatgtga cagatacatt aggattccca atcttaggaa cagttccaga
     2761 aatgtcagcg aaagaattga atgctggtat ccgtaaaaaa ggaccagctc agacacaacc
     2821 aaaagctaca aacgataaaa cagcgccatc acgcagaagc cgctcaagag tctaggagga
     2881 aagaaaatgg cacgaacaca gaaacaaaaa gcagcccaaa ctcatgcagt cagtttggtc
     2941 acactcacca atccctcttc accaatcgct gaacaatatc gtacgattcg gacgaatatc
     3001 cagtttgcct ccgcagctgg tcagcaaatc aaaacgattg ttgtgacttc atcaggacct
     3061 ggagaaggga aatcgaccac tgcagcaaac attgccgttg tttttgccaa atctggtcaa
     3121 cgggtgctgc tagtcgatgc agacttacgt aagcccgtca tctataaaac gttcaagttg
     3181 aacaacgcaa gcggattaag tactgttctt agttcatcag gaagtgtagc agatgagatc
     3241 caacgaacac cagtcgacaa tttgtcgatt ctgccaagtg gacctaaacc accaaatcca
     3301 tcagaactac taagttcgcc aagaatggat cagattttag cagaagcaag acaactattt
     3361 gatgtagtga tcttcgacat gccgccagtc gttgccgtaa cagatgcaca gatcatgtct
     3421 tcaaaaacgg atggcacctt attggtcgta cgggaaaata cgtcacgaaa agaatcattg
     3481 actaaagcaa aagaactgtt agatatggta caagcacgag tcttaggtgt cgtatacaac
     3541 ggagcagaac acagcaaaga tgctggttat tactacggaa attaaggaat aagaagagag
     3601 gagacaagag aaatgatcga tctacattgc catatcctac caggaatcga tgacggggca
     3661 gaaaacttag aagcaagtat tgcaatggct gaaaaagcga ttcagcaagg cattacgcat
     3721 attttatgca caccacacca caataatgga aaatacagca atgaaaaatc acaagtcatt
     3781 tctctagtcg cttcgttaca agccgaatta gagaaaagac agttgccttt gacgttattg
     3841 gaaggacaag aagtacgtat taccggaacg ctcatcgaag acatccaccg agatgaaatt
     3901 ttatttacag atttagatga tacatatctt ctgatcgaat ttccgacact ggaagtgccg
     3961 ttatatgcag aacggctttt ttttgagttg ttagaactag gaaagatacc agtgatcgtc
     4021 catccagaac gcaacgcgca ttttcgagaa gacccaaatc atttgcttcc gttcctagat
     4081 atgggatgtt tggcccaact tactgcgcca agttatgttg gtgtatttgg caaagatatc
     4141 cagaaaacag ccaaaacaat ggtcaaacat aatctcgtgc agatggctgc ttctgatgca
     4201 cacggggtct ctaagcgcac cttttactta aaagagtgct atgagcagat tgccaaggag
     4261 tttggtaagg aaaaagtagt acagatgaaa caagtcgcaa aggatctgat caacggggat
     4321 gagatcaatt atccaatcta tgaagaggta aaaaagaaga agtttggttt attttagttc
     4381 tttattcgta gataaaaagg aaatgaggag agagtgagag atgtatagaa aaaactcaag
     4441 tggttggtct aaacatattg attttatttt attagactta ttttgtgtcc agcttgcttt
     4501 ttatatatca tatgtaatgc gacagggtga ctggaatccg tatgtgattc ctatttatcg
     4561 ccacatggca atttttatag aacttgagaa tcttacgatt atatttttat ttgaggcata
     4621 taaaaatgtt ttaaaaagag gatattataa agaggctgta gcttctataa agcaatcttt
     4681 tatgctgtta cttgtgtgca gtttatacct tattacaatg caggatggaa atgattattc
     4741 cagagtttct ttatttataa tgggggtggt gtatggatta ttaacatata taattcgtat
     4801 actttggaaa gggttgttgc atcaccgcat gaaaaacggt gaagatgtat cgttagttat
     4861 tgtaacatct caaaagattg caaaaaatgt agttcgtaat cttaaagaga agaattatgg
     4921 catgtataaa cttagtggtg tgattgtagt agacagagat atgtatggaa ctaccatcgg
     4981 aggtgtccca gtagttgcaa atgctgataa tgcagcggaa tatcttttac agaattgggt
     5041 agatgaagta ttcatcaatg ttgacgaaag tgttccatat cccaaagaat taatcgccag
     5101 atgttcggaa atgggacttg ctgtacatat gaatcttaca aaagtgtctg atagtacacg
     5161 tggaaaacaa tttattggcc gagttggtga ttatactgtt attacatcta gtattaatgt
     5221 tatgacgatg aggcaagcat ttataaagag aacgattgac attcttgctg gaattattgg
     5281 atgtattgca acaggtgtta tttttatctt cgtagcacca gttatttaca tcaaatcacc
     5341 agggccgatt ttctttgcac aagaacgtat tggtcaaaat ggtaagacat ttaagatgta
     5401 taagttccgt agtatgtata tggatgcaga agaacgcaaa gcagagttga tgaaagaaaa
     5461 taagatgagt aataatctca tgtttaagat ggattttgac ccaagaatca ttggcaataa
     5521 aatacttcct gatggaacaa agaagacagg aattggacaa tttattcgat ctacatcatt
     5581 ggatgagttt ccacaatttt ataatgtcct aatgggaaaa atgagcctgg tggggtttag
     5641 accttgcttg aagtcagaat atgagaagta tgattttcat catcgtgcga gaattgcgat
     5701 gaaacctggg attactggaa tgtggcaggt gagtggtaga agtgatatca cagacttcga
     5761 agaggttgta aaacttgatg cagaatatat caggaattgg agtatgggat tagattttag
     5821 aattttgttt aggacagtca aaactgtgct tcatagaaac ggttccatgt aagataaaga
     5881 tactatagaa ggagtaaaac gtgatggcaa gaaaaaaatt aaaaatctgt atgctaggtc
     5941 ataaaagaat tccatcaaga gaaggtggaa ttgagatagt ggtagaagaa ttggcaacgc
     6001 gaatggttgc acttgggcat gaagtgactt gctataatcg aagtggtcat catgttagcg
     6061 gaaaggaatt tgaccagcat aaaaataaag aatataaagg tgtaaaatta aagactattt
     6121 ttacattaaa tataaaagga attgcagcaa tgagttcttc agtatttggt ggaattagag
     6181 cagcattcgg aaaatatgat attgttcatt ttcatgcaga aggaccatgt gctatgttgt
     6241 ggttgccaaa actttttggg aaaagatgtg ttgcaacaat tcatggtcta gatcatcaaa
     6301 gagaaaaatg gaacaagctt gctagtacat acatcatgtt aggggaaaag tgtgctgtaa
     6361 aatttgcaga tgaaataatt gtacttagtg aaagcgtcca aaattatttt gaagatatat
     6421 atggaagaaa aacaaggttt ataccaaatg gcgttaaaaa aattgaaata aaatcagcag
     6481 gattgattac agaaaagtat ggattaacaa aagattctta tattttgttt ttggggcgat
     6541 tggttcccga aaaaggaatt cggtatctaa ttgaggcatt taaagatgtt cagacagata
     6601 aaaaacttat aatagccgga ggaagctctg atacagatga atttgcaaat gaactaaagg
     6661 aattagcaaa aggtgatgag cgaattatat ttactggatt tgtacaagga caggaattag
     6721 aagaattata tagtaatgcg tatatctata cacttccaag tgatttagaa ggaatgccat
     6781 taagtttgtt agaagcaatg agttatggga actgttgtat agtttcaaat atctcagagt
     6841 gtacggaagt agtagaagac aaggctatga tttttaagaa atcggatgta agtgatttaa
     6901 agataagatt agaagaggca tgcaatcaat cggaaatggt taaagttttg aagaatcaag
     6961 ctactgagtt tatttgtagt aaatataatt gggataaaat cgtacaagaa acattaaatt
     7021 tgtatagggg aaatatataa tgattcgaat attacagtgt gtgaatgata tgcatcgtgc
     7081 agggttggag acgatgctaa tgaactatta taggaatata gatcgaacta aaattcagtt
     7141 tgattttttg acacatcgtc catataaaag tgattatgat gaggaaataa taagtcttgg
     7201 aggaaaggtc tattatgcac cgagacttta tccacaaaat tatcctaaat attttaaatg
     7261 gatggaacaa ttttttaagg atcatccaga atatgagatt gttcattctc atattgatgc
     7321 gatgagttat ttacctttaa aagctgcaaa aaaagctggg attccgatac ggatagcaca
     7381 tagccataat acatcgatag atagagattt taaatatctt ttaaagcaat attatcgatg
     7441 taagttaacg tctgttttga cacatgaatt ttcatgtgga aaagtagcag gtgatttttt
     7501 gtttcgaaat gataaattca ctttgattcc aaatgcagtg gatgctaaaa aattttatta
     7561 tgatgaaagt attagaaatg atgtacgaat gaaattagga atttcaagtc agacgtttgt
     7621 aatgggacat attggaagaa tttcatattc taaaaatcat cgttttttga ttgaaatttt
     7681 taaagaattt cacgctatta agaataattc cgtattatta attattggaa ctggtgatat
     7741 ggaagaagaa ataaaaaatt atgcaaagaa aagtggcata gatgatgata ttaaattttt
     7801 aggaaataga aatgatatag aaaaatttta tcaagcattt gacgtattaa tgttgccatc
     7861 attatttgaa ggggttccgt tagtgggtat tgaagctcaa tttgcagatt taccgtgttt
     7921 cttttcggag aaagttccta cagaagttgc tttcagtgat aagaccaatt tcataagttt
     7981 aaatcaatcg gcaaaagaat gggcgagaga gattgcaaat gtagatatct ctcatcgaga
     8041 ttcagaacgt tcgattttaa taaaggcaga ttataatatt caaacagcat acaaaatctt
     8101 agaatcaaaa tattatgagt tatttgaatt aatacaaaga ggttaaagaa tatgacacag
     8161 aaacattcaa gtataaaaag aattatacat cgcatatccg aagaattgaa tgcaacaaga
     8221 cgaattgcaa agataacatc ttggaaggaa gcatttgcca cgttacaagc taaaattgat
     8281 attcaagtca tgaatcgtaa tggatataat gaaagtaaaa aacagaagga acatttatta
     8341 aaaaaacatg aggtaatgct gaagtattat gaaaagactt tttcagattt tttgaaaaca
     8401 tatgattata gtcaaaatca aataattaat caatcaaaat caccatattc taactgcatt
     8461 tgggtttgtt ggtggcaggg attggatcaa tcgccggaaa ttgtaaaagc ttgtgtaaaa
     8521 tcaataaaac gaaatgcagg gaaacatact gttataattt taacagaaga taattataga
     8581 caatatgttg atataccaaa atgggtggaa gaaaagaaaa acaaaggaat cattacgaga
     8641 acaaattatt ctgatttatt aagattatct ttgctagcaa aacatggagg tttgtggtta
     8701 gacgccacat tttattgtac aaaaccaata ccagatgagt attttgatat cgatatttgg
     8761 tctattagga ggcctgatta tgctcacgca tccgtagcat caggatattt tgcgggttat
     8821 tcattagcat gtaatcaaga gtctagatgg atgtttgcta taattagaga ctttttttta
     8881 aattattgga aaaataatga tatgatggtg gattatttga tgatagatta tatgattgtt
     8941 ttagcacaga gaataaatca tgaaatagca cagacatttg ataaaatacc tagtaacaat
     9001 ccattatgtg acgaattgat taaaaattta aataatatat atgatgaaaa agtatggaac
     9061 ttattaaaga aagatacttt actgtttaag ttgacatgga aacaatcttt taaaaagcaa
     9121 aaagatgata aagttacttt ttatgggatg ttggtagaaa acaaattatt ataaatatta
     9181 gaggtataaa aagttatgaa acacaaggta agtgtgatag taccaattta caatgttgaa
     9241 aaatatttaa gaaaatgtgt ggatagttta ttgagtcaga cattaaaaga gatagaaatc
     9301 gtattagttg atgatggttc gccagatgct tcgggggaaa tagcagatga gtatcaaaaa
     9361 aaatattcta atgtaaaaac aatacataga gaaaatgggg ggttaggacc ggcaagaaat
     9421 acaggaattg agaatgcgac aggagaatat gtggcttttc ttgattcaga tgattgggta
     9481 gaaagtgata tgtatgaaaa attatactta gttgcgtcca aagaaaatgc tgatatagta
     9541 gttagtggac attgtgattt tgcgaatgac aaagctatgg tgaaaaagca acatcctttg
     9601 agtgggaatg tatatgatac gcctaatagt attaaaaatg tacgaaaaaa tttatttgga
     9661 catagtccaa aagatcaaga agtagaggcc ttcccgatgt cagtatgtat gtctttgtat
     9721 aataaaaatc tgctagataa atatagacta agatttgaaa aaattttatc tgaagataca
     9781 atttttaact tgaatgcata tgatgtcgca aataaaattg cttttacaga atatacagat
     9841 tattgttata gaaaagaaga acaagagtct attacaaaaa gtttatctcc aaataagcag
     9901 acggaattta aagaattttt aataactcta aaagctatag catcgaaaga agatttagaa
     9961 tgtcaaatca gagcaaaacg tatggcaatt gattattgta ggctttatgt gggcttagtt
    10021 gatgatgcaa atttgggaat taaagagaaa agaaagtata taaaaaaatt tattgaagat
    10081 gagggattaa ttcaatgttg gaagggatat cctacaaata cgctaccatt tcaacaaaaa
    10141 ttttttcata aaatgcttga atgtaagtgt tatacaatat tgttgttgtt aagtagaatt
    10201 agaaagataa ttaaaaatat gaccagaaaa aaattgttta taatattata aactaaaagt
    10261 atatcaaata atagaaatta acaagttaca aaaaaatatt ataaagaata atattttcta
    10321 aaaagtaaac tatagtaatg tggattatca ccttccaaca gtatataaaa tgagcgtaaa
    10381 aacggctatt tttgccttaa caacgatttt tttgtataca aatacgatat gctcattaat
    10441 tattggaatt tgtagtgctg tttaaattaa tgaaggtgta attatatgag tgatcatttt
    10501 gaaaaagttt gttgagaaga tgtgcttcta gtcatgtgat gggagaaaat aatttaactg
    10561 ttagagtgaa tagttaaatt attctggtta tatgaaaaaa gtagtttcta aaataatctt
    10621 gcagggatta acttaaagaa attgagagaa tagtttcttt gaaatttcta tatacaatga
    10681 gaagctgaaa tttactttta tttgatgact ggaaatagaa attaaatata ttgtattgtt
    10741 acattaaaga aaacttgtat ggaaaaatca gtacaatacc attatttaat gttcttcact
    10801 taaagcgcaa aaaatatcag tttattaaac tcgtatatag aacaaatata tgtagacggg
    10861 gcgaaacgat gagtgtaaaa aaaatgctat ttatggtaag tacaataatt gtattaacat
    10921 cccgattttg gggaattaat actagtttat ctatgcgata ttttattatg gcaatatggg
    10981 atttatattt tatgttaagc tatttttctt atcgtgagaa aacatataaa aaatacgtta
    11041 tcaagaataa cttttggttg actataatgc cgtttgtgat attttctatc tatactctaa
    11101 taatatgggg aattggttca aatgcagaat ttgaaaattt tataaagtta tgttccacgt
    11161 tgctttattt aattcttgca tatggttacg catgtacagc attttactta tttaaggcag
    11221 aaggaattga ttttattttt tggtcaggtg ttatttcata tatgagtggt tcagtttttt
    11281 atttaattgt atcttatggt ttaaatggtt taatttctta tataaaaagt cttataacag
    11341 gtgaaacaaa tactgcaaat tttgctatgg aggtacatga tttaactttt gcgatggggg
    11401 tttttttcct ttattacgta ttttttgaaa ataaaaatac aaaaaaacat aagataaaaa
    11461 ttatcgtatc tttaatttta attttcatgg gattgaagag aattgaactg ttagctttaa
    11521 gtggtgcaat tctagtgtat tatgttttat taaagtgggg aaaaaagatt caaatccgtg
    11581 cattagtgtg tactatttgt gcaactgtta tttcgttagt gtttatttac attatagata
    11641 caggaatttt ggcattgctt atgtcaaatt tgggcattac agatgacggt gcaaggcttt
    11701 cattttatct atattcatct aaattttatg aacttggttt aggatatgta ggaacaggat
    11761 ggacatggtt ttcaaaatac ttttttaatc tttatttatc gcactttagg ttaaatggtg
    11821 gaagaattgc agcaagccta cacagtgata tattaactat ttatatagaa gttggatgta
    11881 tagtttttat tatatggatg ttttggttat tttttgtgaa accgataaga ctaactaaaa
    11941 aatttggatt gaaaacaggg gagtgtgtat tattattaac tatatatatg tttatattat
    12001 atttgacgga taatacgctc acttatccag acactcaaat gatttttctc ttagtaccta
    12061 tgatagtttc gtgggttgat aatcaacaac gaatatcgga atagatagct aaagtatatt
    12121 ttaattatga atttataatt agttgtaaaa gttaatattt aacggacagg aagtagggtg
    12181 aaaaaatttg aaaaaaattt tagtgttagc aaatacatat tatcaaataa tagtagcaat
    12241 acaaatgaaa aatacaattt tttccgatga gtatgttgaa attattattt ctgatcattc
    12301 taaaaacact aaagaaattg cgaaaaaaat agaagaaaaa aaagtgtttg atggctgtca
    12361 ttatttagaa agcaaatctt ttgatgataa tattgggtat tttcaaaaga ttaaggactg
    12421 tcttcagatt tcttgtggta aatcaaatcg atatgcctat tatttgaaaa actgtaaaag
    12481 tgaatatttt gatgaattta tttgtttttc aatgggagag gtttggttgg aaggaatata
    12541 tgcttgctta tatcgaaata ataaaaatgt acaggtatca attttagaag aaggtatttt
    12601 aagctatgga gttgacatta ttccaacagc aagaacaaaa gctatcgcag tactcaatta
    12661 cttaaaaaaa aggactccac tatataacaa aagctataat ttttattgtt tttttcctaa
    12721 tatatataca ggaagagaga atacaataca aattccatta gttacagctg ggtcaagaac
    12781 cgcattgcaa ctttcggata tttttaaccc tatgatagat atttataaag aaaaaaaata
    12841 tatatttttt acgtctgttt atgattttga gggcggagaa cctgtcggag aatatgaatt
    12901 agtatgcaaa atagcagact tagtaggaaa agataatcta attgttaaga cgcatcctag
    12961 agatgtaaga acaatttata aagataatgg atttatcgag gataaaaatt catcaatacc
    13021 ttgggaggcg attcaattgt caggcgattt taacgataaa atatttatga caattaattc
    13081 aggaagtgtt atttcaggta gtacaatgtc tgcaaaacct gtacgcacgt attatatgta
    13141 taaattgtgt aacatagaag gaaatccgtc ttgcaaaaag aatgcgtatg atattgagcg
    13201 attgcttaag caaaaaacga tgaaaaacat tttaaagaat gtgaaaatag cagaaagctt
    13261 agatgatata ctatgagcaa aactaaatat ttaattaaaa atatgggaat attaacaata
    13321 agtaattttt cttcaaaaat tttagttttt ttgttagtcc ctttatatac aagtgtatta
    13381 tccacaacag aatatggcac atatgatttg acaatttcaa cagccacatt attgtttcca
    13441 attttaacct taaacattgt agatgctgtg atgcgctttt taatggataa agataaaaat
    13501 aaaaaaaata tagcatctat agcgattaaa gttatatttt taagcgtgat agtctttgga
    13561 tccgtaatgt atttgttaaa tattacaaaa ttatggcaag atgtttatgg attagaaaaa
    13621 tatatttttt tgtattatat atcctatgta tggaatcaat ttctaataca atttgctaaa
    13681 gggttagaaa aagttaaagc tatgggcata gcaggtatta tcagcacaat tgtaacaata
    13741 attgccaata ttttcttctt gcttattctg aaatggggat taattggttt tttcattgca
    13801 aatattttat cacagattat ttcagctact tatctgtcag tattagtgag aatatgggaa
    13861 tatatcgatt ttgaggctaa agatcctcag ctaaagagag aaatgctaaa ttactcgatt
    13921 ccattaattg caactgttgt tggatggtgg attaatagta cagctgatag gtatgtggtt
    13981 tcctttatag taggtgtctc ggcgaatggc ttattgtctg tggcatataa aatacctcaa
    14041 ataattaata ctttgcaggg aatatttata caggcctggc aaatttctgc aattaaagaa
    14101 tatggagata atgagactgc aaaattttat ggaaatacat ttgttatgat taatttgtta
    14161 atgtgcataa cctgttcaag tcttatcata ttaactagac cgttttcaca tattctttat
    14221 gcgaaagact tttatgaagc gtggaaatat gttccatttt tattaatagc taatgtttta
    14281 aattgtgcat caggtctgtt aggacctatc ttatcagcaa aaaaagattc taaatccatg
    14341 atgtggtctg caatcatagg ggcattagtt aatgtgatta tgagtgtagt ccttgtttat
    14401 aagatagggg ttcaaggtgc cacaatagcc actgttatat gttcatatgt aatatatgtt
    14461 gttcgtaaac gagctgtggg aaaagatatt tttataaagc attatcatat tgttgtggaa
    14521 tcttggggat tattgtttgt tcaggcaatc atagaaatat attttaaaaa ttatgtaata
    14581 gaaattataa ttatgattat tttaattatt ataaatatca gttatattaa gcagttgtgt
    14641 tatagaggaa gaaacattat ttcaatgatt aagagtcgag agcacaaacg gtagacgatg
    14701 ttatttttat aaaaagatat aatttattaa tggtcgataa ttatgaaagg aaaaatattc
    14761 ttaaaaaaaa gagtatagga tgtcgtatga aaatagtcgc tatagtacca atgaagttaa
    14821 ataacaaaag attgccacaa aaaaacacga aagcttttac caatggaaaa ccattgtgtt
    14881 attatatact ttcaacactt ttaaaagtaa aacagattga taaagtgtat gtctattgta
    14941 gtaacccaga tattaaagaa tttataccag aaggtgtaac atttttaaag agatctagtt
    15001 ccttagatca ggatacaacg agtattacac aggtattagc cggtttcaca aaagaagtag
    15061 aggctgatgt atatgtaatg acacacacaa cagcaccatt tattagcgaa aaatctattg
    15121 aaaaaggact agatgccgtg ctgacaggag aatatgattc tgcatttgct gcaaaaaaat
    15181 tgcaagattt cttatggaaa gacggtgaac catttaatta tgaattggac aatattccta
    15241 gaacacagga tttgccgcct ttatacgaag aaactagtgg attttatatt tataatcgca
    15301 atgtgatgac cgagttgcat agaagaattg ggaaaaaacc ttgcatagtt gaagtaggtg
    15361 agattgagtc agttgatatt gatgaagccg aggattttat gattgctgat gcgatttata
    15421 atcatcttat tttacaaggt agttaagaca gggggaaggt taggatgaac aatgtacaga
    15481 ttttagattg cacacttaga gatgggggct attgtaacaa ttgggaattt ggatttgata
    15541 atacaaaaaa aattatttct ggacttatag aatcaggaat tgagattata gaatgtgggt
    15601 ttctcacaaa taaaacagta tacaataaaa atgttacaaa atatacgacc ttagaagaat
    15661 tagcacagat aattcctgaa aaaagagaag gaaaattatt tgtagcaatg atgaactatg
    15721 gcgaatataa tatagaggat cttccagatt atgatggttc atctattgat ggaattagga
    15781 ttgcgtttca taaaaaaaat tgcaatgaag cgttgaaatt atgtcgtgag ataaagaaaa
    15841 aaggctactt agtttttgtt caagctatgg tatctctcaa ttatacagat gaagagtttt
    15901 tagcagtaat aaaaaatgtg aatcagttta aaccatacgc tttttatatt gttgatagtt
    15961 ttggaatgat gaaaggaaaa gatttaactc gtctttttta catgattgag cataatctag
    16021 aaaaagatat acagataggt tttcactcac ataataacat gcagcttgca tattctaatg
    16081 cacaaaaact tataaccgta caaacaaatc gaagcctgat tattgattct tcggtgtacg
    16141 gaatgggaag aggagcaggt aatcttaaca cagaactatt tgtagaatat ttgaatgata
    16201 atgcaggaaa aaaatatcaa ttaaaaccat tattatatat aattgatgaa atactaaata
    16261 gtttctatca gaagagttat tggggatatt cattaccaaa ctatatttca gcagttcata
    16321 atgctcatcc taattatgca agctatctgt catataagaa tactttaaca attgaagcaa
    16381 tgaatgaaat attcgaaatg atggatgaag aaaaaaaggt atcttatgat aaacaatata
    16441 tagaagattt atactacaaa tatatggaaa ctgggaaaat acaggaggaa tatatggaag
    16501 aactgagaaa atttctctca gacaaaaaaa ttctactgat tgcaccagga aaaagttctg
    16561 tagatgaggt agaaagaata aaagagtttg ttaccaaaga agaagtcgta ataattagtg
    16621 taaattttga atattctcat atagatatag attacgtatt tttaagtaat ttaagacgtt
    16681 ttcatgaatt accgaaagaa agcagaacta aatgtattgt tacatcaaat atacaagcat
    16741 cggatgtata tttacggacg agttataaaa agttgttatc tgaaagggaa gttgtaagag
    16801 acaatgcagg attaatggca attagatttt tagccgatat gaatgtggat gaaatattct
    16861 tagctggatt tgatggatat tcacataatg aagatgagaa ttatggtgag caatccatgg
    16921 aaattataac aaaatttgca ttattagatg caatgaacgt gcaaatgaga gatgaattgt
    16981 cagaattagc taaaaaagta aaggtgacat ttttaacgga tccacgttgg gttcgaattg
    17041 ataagtagta gtaataatgt ttttaaaatt ttgataaaga gatagtgaga gaataaaaat
    17101 gggtaaagtc ttaaataaaa aagaagaaaa atatttaagg gccgatgggg cgagatgaaa
    17161 ctctaatttt gaacttttaa gaatcatttc tatattgtgt attgttgctt accatgctaa
    17221 tttgcgttta aattataatg cagacggaat tatagtacat ggttcattaa ctgctaacca
    17281 gattttcttg aattatattg gtatttgggg tcagctagga gttaattgtt ttatatttat
    17341 ttcggcatat tttttaagtg agaaaagaaa cattcacttt gaaaatgttt tgggaattgt
    17401 attagaatgt attttttata gtgtattagt ttatggaatt ctttgtgcat gtggaataga
    17461 aacattttca ttgaacagct ttgtaaaaga aatattatca tttgctctag gtagatattg
    17521 gtttattaca tcctatttag cattgtatat tctaagtccg tatttaaata tcatgcttaa
    17581 caatctggaa aaacttcagt tgcaaaaaat aagtatgtta ttgtttatag gtgtatgctg
    17641 ttatcgtatg ttatttaaaa catctttgtt tggggattgt gctgttttaa ttgcactata
    17701 tgtcatatgt tatacactga aaaaaacgat aataatattt ttgagagaca cagaatcata
    17761 ggaacaattg tatgtataac agttatacca cttctcatat ccataggaat acttttcaaa
    17821 tttataccaa atgcaatggt taaccagatg gttcatattg gttctccatt gatggttata
    17881 gcaagtatat ttttatttta tgtatttaaa aatttttcat tttacagtaa gtatataaat
    17941 aaacttgcga gaaccagttt aggggtatat attttacatg aaaatcatta tttcattgat
    18001 ggtatgaagt ctagaggctt aatatgggat gggatatttg gattaggcaa aaggttttta
    18061 gatagggatt tttggatttg gtttataatt gcagttgtag ttgtgtgcat aatttgcatg
    18121 gctatcgatg ttgtaagaga aaaatttgaa agacagattt ttaaaattaa gagtgtaaag
    18181 aacctgtgta aacttatgaa tcatgttata aatatatacc cataattaat aaatgaggag
    18241 aaaagaagtg aaagttatat cattcggaga attattattg agacttgcag cacccggtta
    18301 ttcaaagtta tttcaaagag atagtttgga gactacattc tgcggagggg aagctaatgt
    18361 agcggtatcc ttagcaatat ttggatatca atcagaattt ataacaaagc ttccggattc
    18421 agatgttgga tatgcggcag ctaatgcttt gcgttatttt ggagtaaatg ttgataatat
    18481 tatatttgga gagggacgca tgggactgta ttatttagaa aaaggagcag ctcagagacc
    18541 atctaaagta atttatgaca gaaaattttc tgcaatttcg ttagctgata gtgatgaatt
    18601 taagtggaag gagatcctaa acgatgcaaa ttggtttcat tggacaggga taaatccagc
    18661 attgtctgag aatctctttg agacgtcctt agatgcatgt caggctgcca aaaaaagagg
    18721 tataacaatt tcttgtgatt taaattatcg atccaagctt tggacatcag aggaagcaaa
    18781 agaaaagatg gaacagatac taccattggt tgatatttgt atttgtaatg aagaagatgc
    18841 agaaaaagtg ctaggaatta aagctgagca tacaaatatt aatagtggag aattaaataa
    18901 agatggctat gtgcaggtgg ctagggagat tcacaagaag tttggatgta ggtatgtagc
    18961 tacaactctg cgtagaagtt attcggcaag tagaaatggt tggagtgcaa tgttatacga
    19021 agcagaaaaa gataaagcgt atttttccac agaatacaac atacaaattg ttgatcgcgt
    19081 tggtggtgga gacagctttt ctgctggtat aatatatgcg ttatgtgaaa atatgtccgg
    19141 acaaaaggct attgaatttg cgactgcatc tagttgttta aaacatacta tagaaggtga
    19201 ttttaatcga actacaattg aggatgtata taatttaatg aatagcggtg gaaatggtcg
    19261 cgtgttgcgt tagtcaacat ataaagataa atcacagtaa tttttatggt gattatctgt
    19321 cttagtagtg attagaataa cgtgaaaata aattgttgag cgtttatact gttttgaaaa
    19381 ataaatttaa catattgaaa aatacaaata tatacgtata ttataaagcg ccgattgtaa
    19441 aattaagcta gacaactaaa acagtcattt gtgctacact caaaatagtt ccgaccaaag
    19501 aattataagg agtgagtgca aataacctat acctatctta caacggatga acttgtaata
    19561 atagagtctt atttgaaaat taaccaatct gttgctaaaa ctgcgcattg cttgaatcgt
    19621 tcaagtcaaa cgatccataa agtatatctg ttcttcaagc aaagaaaatc agccttagaa
    19681 ta
//
LOCUS       DAFENC010000050        19507 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.052, whole genome shotgun sequence.
ACCESSION   DAFENC010000050
VERSION     DAFENC010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19507
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.052"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(460..1089)
                     /gene="udk"
                     /locus_tag="LP493_002299"
     CDS             complement(460..1089)
                     /gene="udk"
                     /locus_tag="LP493_002299"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HBL2134418.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1173..1868)
                     /locus_tag="LP493_002300"
     CDS             complement(1173..1868)
                     /locus_tag="LP493_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HBL2134419.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1881..2597)
                     /locus_tag="LP493_002301"
     CDS             complement(1881..2597)
                     /locus_tag="LP493_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HBL2134420.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2927..3532
                     /locus_tag="LP493_002302"
     CDS             2927..3532
                     /locus_tag="LP493_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HBL2134421.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3857..4180
                     /locus_tag="LP493_002303"
     CDS             3857..4180
                     /locus_tag="LP493_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBL2134422.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4362..5732
                     /locus_tag="LP493_002304"
     CDS             4362..5732
                     /locus_tag="LP493_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBL2134423.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5862..7163)
                     /locus_tag="LP493_002305"
     CDS             complement(5862..7163)
                     /locus_tag="LP493_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBL2134424.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7393..9351)
                     /locus_tag="LP493_002306"
     CDS             complement(7393..9351)
                     /locus_tag="LP493_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HBL2134425.1"
                     /translation="MAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9528..9794)
                     /locus_tag="LP493_002307"
     CDS             complement(9528..9794)
                     /locus_tag="LP493_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBL2134426.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10304..12430)
                     /gene="pnp"
                     /locus_tag="LP493_002308"
     CDS             complement(10304..12430)
                     /gene="pnp"
                     /locus_tag="LP493_002308"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HBL2134427.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12618..12887)
                     /gene="rpsO"
                     /locus_tag="LP493_002309"
     CDS             complement(12618..12887)
                     /gene="rpsO"
                     /locus_tag="LP493_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HBL2134428.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13138..13701
                     /locus_tag="LP493_002310"
     CDS             13138..13701
                     /locus_tag="LP493_002310"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBL2134429.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(13954..14475)
                     /locus_tag="LP493_002311"
     CDS             complement(13954..14475)
                     /locus_tag="LP493_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HBL2134430.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14478..15320)
                     /locus_tag="LP493_002312"
     CDS             complement(14478..15320)
                     /locus_tag="LP493_002312"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HBL2134431.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15313..16038)
                     /locus_tag="LP493_002313"
     CDS             complement(15313..16038)
                     /locus_tag="LP493_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HBL2134432.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16214..16510
                     /locus_tag="LP493_002314"
     CDS             16214..16510
                     /locus_tag="LP493_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134433.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17078..18670
                     /locus_tag="LP493_002315"
     CDS             17078..18670
                     /locus_tag="LP493_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBL2134434.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18683..19423
                     /locus_tag="LP493_002316"
     CDS             18683..19423
                     /locus_tag="LP493_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBL2134435.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
BASE COUNT         5580 a         4002 c         3702 g         6223 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaaa cagttggctg gtgactgttc aaaaagcaga atccttgctt
      421 ttcaaacggt cgcagtccgt tcaactgttt cgctgcgcac tatttatggt ttaagaaact
      481 agctactttt gttgtaatca aatcaatagc aacgtggttt tctccgcctt ctggaacaat
      541 gatatccgca tagcgcttcg ttggttcgat aaattgatga tacatcggtt taacaactgt
      601 caaatattgt tcgatcacgg agtccaatgt gcgtccccgt tcttccatat cccgtttgat
      661 acgacgaatg atacgaatgt catcatctgt atctacgtat actttgatat ccatcaagtc
      721 acgcagacgt tcgtcttcta aaatcaggat tccttctaga atgatcactt cttttggttc
      781 ctgaatgatc gttgcctgac ttcttgtatg cgctacatag tcatacacgg gtttttcaat
      841 ggctttatag ttcagtaagt cgcctacatg ctgaatcagc agatcattat caaaggcaaa
      901 tgggtgatcg taatttgtgt tcaatcgttc ttcaaaactc aaatggctct gatccttgta
      961 ataagaatct tgttcaagca tcatgatgga atggtccggg aagttgttga aaatcgcacg
     1021 gctgacactt gtctttccgc ttccggatcc acccgtcaca ccaatgataa ttggcttgct
     1081 ttttgtcatt gactaaaacc tctttcgtat ccgttttttc attctaatct attatagcga
     1141 aaaaacacga aaatgctata tttttctgaa aattaatcct tttcaatttc caataatgaa
     1201 taaagttcct ctaatgaatc gattcgataa gtaggctgga tttcttcgat ttctggtaat
     1261 ttatttctat tgaaccaaat cgtatcgatc cctgccatat ttcctccttt gatatcagaa
     1321 gtcaaagaat caccaatgat cacagtttgc tttttatcaa aattaggaat gtgggaaaag
     1381 acatgatcaa aaaattcttt catcggcttt tgcgctccga cagcttctga gacaaagata
     1441 tccttgaagt aatcaagcat tcctgcatct gttaatcgcc gatgttgcgt gtgcgacaca
     1501 ccgttcgtca caatataaag atcagcatgc ggatggacct ttttcaggat ttctagactt
     1561 cctggaacaa gatcatgacc ttggttcaag tagtggcggt agcgtttttc catttgatca
     1621 ctatctactg ttttcccaaa ttgctggaaa agtaacccaa aacgactgcc tattatttct
     1681 tctcgtgata gtctgccttt ttcaaactcc tgccataaat gatgattcaa agccttatag
     1741 ctggtttcga tttctggtgt caatgtgatt ccttgttctg caaacaaagc acttaaagca
     1801 ttggcttcag ttaattgaaa atctaacaat gtatcatcta catcgaacaa taaagtttta
     1861 tatttcatct ttttgacctc ctatttaaaa taaatactta actttttcat ctctgctaat
     1921 gtcaacgatc gatactcgcc tactcctagc tgttcatcta attccaatgg tcccatgctt
     1981 agccgtttca atgcggtcac tttctttcct tgggctaaga acatcttttt gacttgatgg
     2041 aattttcctt cttggatcgt caataaaacc gtactttggt gcttgtctgc tttgagtatt
     2101 tttaaatcag ccggcttaca ttgataccca tcagcgaata cgattccatt ttcaaatgct
     2161 gttacgtctg ccggtgtcac cctttcgttc acaactactt gataagtctt tgaaaccttt
     2221 ttttctggaa gtagcatttc atatcccaat tgtccattcg aagtgatcag caatagtcct
     2281 gttgtatctc tatctagtct tcccactgga tataatggtt ggaaacgatc ggcacttgca
     2341 atcagatcga ttactgtcgt cttttctgga tctgatacag ctgtaacagc tttttcaggt
     2401 ttattgagaa gataatagga ctcatttgtt tctaagtgtt cacctgctac ttcgatttga
     2461 tgcagtaaac tatctacatt tcgattttgt cgaaattcga ctgtgccatc tatcatcact
     2521 tgcttcaaag caaacagccg cttcatttcc ttgcgtgtcg tttctaattt ttcttctatt
     2581 aatttatcta aacgcatgct gtttcctttc ttattactac taattaatta taccttgaat
     2641 attcttgctt gcaaatacat catcatagtt attccttgac ttaattaaca gttcacgtta
     2701 cggttaaata gtaaagtgaa ttggatttct catacacagc gtaatgacct ggtggagaaa
     2761 agttgaatcc tgactttcta aggggagatg cgcgcatctc tccttttgcg cttttttaag
     2821 cgccctgcct tcgatgatgt gcacgagatt agcctttaga attcacttaa ataaaatctg
     2881 tccgttacca aagcagacag tcacatttta aggaggaatt ttggttatgt cagtatcatt
     2941 agaagtaagt aaaagagaag tacgtccccg ttcattaaga aacaaacttc gtcacgaagg
     3001 gaaagttcca gctgttgttt atgggtataa agtagaaagt acccctatct cattcgatgg
     3061 tttgacacta agcaaattgt tgcgtgaaca tggagcgaac acagtcatca cgatggacat
     3121 cgatggacaa aaagtcaata cattggttca caagatccaa acgaacactt ttaccaatca
     3181 tttcgaacat gcagaatttc tatctgtaaa catgtcggaa gaaacagaag tcgaaacaga
     3241 agtcgttctt gttggcgaat cagtgggtgc taaatctggt ggagtgttag ctcaaaactt
     3301 gtatacagta gtcgtatctg ctacaccaga caaattgcct gaacgaattg aagttgacgt
     3361 gacaaacttg gaattaggtg attctattac agtagccgat cttccaaaaa acgacgatta
     3421 caaattcgtg accgacagtg aagagcaaat cgctgctgta gtcgctcaaa gtgaagaaga
     3481 aagcacaggt gaaggtggcg aaccagaagt gatcggttca acagaagaat aatactgaaa
     3541 caatcaggtg gtgttagaag cggcgggtca gcagctttta acacgccttt tttatttcta
     3601 atcgtttatt ttcatatggg gcttccactt ttgtaaatgg ctttacaaac gaaaaatcct
     3661 aatttaccaa gcttttcctc gcatactttt atcgtacctt tataaaaatt tatactttga
     3721 aaaaaagtat tcaattattg ttgcattttt cctgattctt tattagaatg aaccctcgtt
     3781 gaagtaagta tttctagttt atcctaggat taattataaa aataaaacat tcgttgattc
     3841 gaaggaggtt aaacagatgt ttgaaagttt tgatagcagc cgcaaccgtt acgcttcagt
     3901 tggtgtcgta tcaagtttgc cagatgaatt gattgacagt atatggttta ttattgacct
     3961 agatcttaag ggagtcattc cattagaaaa tatattaacc tttgatttga tcgaaaatcg
     4021 tggaaaagtg acgatgcatt tttctcaagc aggaagcaat gtggaaatgg atattgattt
     4081 gccgtttgcc tattcgaacc aatttcctgc tcaagtatac gcctatgatg acggtacgag
     4141 agaaacgatc cttttaccaa gtgagattag acaatattaa ggtgatagat aaacgtggat
     4201 gtcccttatt ttacagacca ggccaagttg ttgattcttt gactcaattc ttggcttctt
     4261 tttatggagt ttcataaatt atcattgatt tctaattggt attctcagga taaacgctat
     4321 atactactaa ctaaatttta aagatataag gagtttaaaa gatgcgcgat ttaacaaaag
     4381 gaagccccgc taaactgatt ttgatgttca ctgttccttt actgatcgga aatgtttttc
     4441 agcagttcta caatatgatc gatatgatca tcgtgggtca gacgctaggt aaaaatgcgc
     4501 tggcagcggt tggtgcaact ggaagcctga catttttgat cattggcttt gcccaaggtt
     4561 taacagctgg tttagccatt attaccgcac aacgttacgg tgcaaaagat tatcggggtc
     4621 tgaagaaaag ttttgctgct agtgttgtca ttagtcttgt cgtcactgtg attttaactg
     4681 tcctaagtct cctgtttatt cgtccgatgc ttcaattgat gcaaactcct cctgaaatac
     4741 ttgatcaagc acaaacattt atttcaatta ttttattagg gatctttgca tcagtcagtt
     4801 tcaatttgct ttctaatgtc attcgcgcac ttggtgacag ccgcacacca ctattctttc
     4861 tgatcattgc ggtcatcatc aacgtcgtac ttgatttgat ctttattatc tattttggca
     4921 tgggtgtgga aggtgcagct attgctacag taatcgcaca agtttcttcc agcgtactgt
     4981 gtctagtgta tatcaagaaa aaaatgcctt tgttacagtt acgcaaaaaa gatttcaaat
     5041 ttgaaaaaga agagtttgct gtacacctaa atgctgcttt gccaatggcg tttcaatctt
     5101 cgatcatcgc tgttggtgct atcgtgttac aagcagcact aaatagtcta gggacagatg
     5161 tcgtagctgc tcaagccgct gctggtcgta tcgaccaatt tgcaaatcag ccgatgatgt
     5221 catttggtat tgcaatggca actttcactg cacaaaacta tggtgcgaaa gaatatggcc
     5281 gaatcttgca aggggtacgt caaactttac tgatgagtgt cggatttagt ctcttagcag
     5341 gtgctatcgt cattttcttc ggtcatttct ttgttcaatt gtttgttagc ccatcagaaa
     5401 cacgtgtatt tgaattagca caaacctact tcaatatcaa tgggtctctt tactggatct
     5461 tagcagtcct gttcatttta cgctacacac ttcaagggct tggacaaagc aagatcccta
     5521 cgatcgccgg tatgatggaa ttgcttatgc gttcttttgc agctatcgtt cttacaggaa
     5581 tgtggggata cccaggagca gcagcagctt ctcctttagc ttggatcggt tctgttgccg
     5641 tgttgcttta ctcttatatg cgttcgatga aacaattgaa acacatgggt gaagaggaac
     5701 atttcacatt agaacatgca gaagcaagat agccttgatt aaaagaaatc gttgcggcta
     5761 aaaatgaaaa cttttattga aaatatcttc ttcgtttacc gaaaacaggt tttttagata
     5821 acaaaaaggc tgtgacaaaa aatgtcacag ccttttttct tttattctat ttttctttcc
     5881 gtggactcta ctttgaaata atcgatatgt gcatgctggt attctaatac cgtgaaacgg
     5941 aatgatgcaa tctcaatgat tgttcctgct tttatttctt tatatcggct agaagcaaag
     6001 cccgcaagtg tagtaaaatt cgtttcttca aactctggaa tctctacatg aaaataacgc
     6061 tggaaatcat ctaatgttag tttgccggag atgatataag agccatctga ctgttccgct
     6121 atcaatgctt cgtccaaatc tgtctcatct cggatttccc cgacgatttc ttctaaaata
     6181 tcttcaatcg tcactaagcc gcttgtccct ccgtattcat cttttaagat agcaatatgc
     6241 tttccctttt ttcgcatgat cgtcaataat ttttttatag ggatcgtttc agttgttacg
     6301 atcggctctt caatcaactg ttctactgtc agctggtcat ctttataaga ttgcttgatc
     6361 aaatctggca aggtgacata acctaaaaca ttgtcttttg attctaagat aaccggatag
     6421 cgagtatgtc cttgttcaat cgaagctttt atcgcttctt tgacggtttc tgaagcttcg
     6481 aatacttgca tggacgtacg gtctacttgt atatcttttg ccaaggtatc atcaaattca
     6541 aacacgtttt ccaaataatg atattcttct ttggtcaact ctcctttttc ataagaattc
     6601 aatgcgacta atgtcagctc ttcttgagac aatgtctctt ctccttcaga tacgagacgc
     6661 acacctaata gcttccctag ccctgcagct gaatgattca atacccaaat aaaaggaaac
     6721 attactttat aaaaataatg aagtggttta actacgaaca agacgacctt ctccgtattg
     6781 acgatactat agctcttagg aagcagttcg ccaataacca catcgatata cgtaactaaa
     6841 ataaatccca gcgccacaga gattgtactg ctaatagccg aactaaaagg tagtttaccg
     6901 atcactggtt ctagtaaagc cgcgacagat ccttcaccga cccacccgat gatcaaaccg
     6961 gttagcgtaa ttcctaattg actagctgat aaatagttat ctaaatggtg tgtaacatga
     7021 agagctagct tggcgttctt tacattttcc ttttctagtt gttccaatct tgatcgtctg
     7081 attttcacta aagcaaattc acttgctaca aaaaatgaag taattgcaat catcaaaaat
     7141 aaaataatga aattgataac catattctcc cgcctttctc tttttctatt gtaccctttt
     7201 tctacaaaaa gattgaaaat aatgcgtatt catatttagg aataaaaaag gagatgcggc
     7261 atttttcagc cacatctcct tatcacttca aaatcattgc gttacttgtt gctaaacagc
     7321 tttttcatga cctctgataa acggtgttca agtagctgac attcgacatt agttcaggtc
     7381 aaagcgctac tttcacaacc gctctttcaa ccatgttttc cgagtatttc caatgataag
     7441 cggaacagtt tcatgtttta cttcgctgta ctctagccca aaccatgttt ctggcgaggt
     7501 agcgattttt ttgattgcca gttttgcctg catgatttga cgttgccatt ttcctagagt
     7561 tgtcacattg gaaactactt catcaatcag gacaaattgg aaatcgccaa cttctcgccc
     7621 tggtgtcaga gagtatcttt gtggctgttt tggcaaacgg ccttgtttca tcaaatcatg
     7681 gatgacttgg cgaacatata cgttgatttc ctgttggacc ctgaaaccta agaacagatt
     7741 cacttggaca ataaaatcag tgtccatcat atctacttga tattctttcg tatatggctc
     7801 atccgtcact tccacatgaa caaaccaata gactcgtgct cttttaggcc gtttatctaa
     7861 aatcgaatag atgaactgtc ggccaacttt atcttcagcc atatcaggaa ccaagaagac
     7921 cacatttgtc tgatagattg gtaaagaagt atcatcacgt aattctctaa gctgcgggat
     7981 ataatctctc aaagacacat cctcggttga cgattcgcga ataatgttcc cttgttccca
     8041 aataaacatc acgactaaga tgatcaaacc aatcagaacg gctacaaaac cgcctcggaa
     8101 gaatttgaca acacttgaga taaagaaaac gacttctatc gcaccgaaga aaaaggtaac
     8161 taaatatgca agccaacgag aatgcccatt ttggataaga taaaagtaaa gcagtgctgt
     8221 tgtcatcaac atcgtcacag tgatcgatag accgtaagca gcttccatat gatgagacgt
     8281 tcggaatgtg acaaccacta gagaacaggc gatccataaa atcagattga ctgctgggat
     8341 atacatttgc ccgatactgt tcccaggata catgatcttt aaccgaggca gcagtttcaa
     8401 cttgattgct tctgaaacta gcgtaaacga acctgtaatc aatgcttgcg aagcaatgac
     8461 tgcagcgact gttgcaaaag caacgccgat cacgatccaa ctttgaggca tcatttggaa
     8521 gaatggattc aggttcttga tttgctgtgc ttcagggttt tgataaacat tcaacaacca
     8581 cgcagcctgc ccaaaataat tgataaccaa acaaattttg acgtaaggcc agctcagacg
     8641 aatatttcgt ttgccgacat gtccaagatc ggaataaagc gcctctgcac ctgtcgtagc
     8701 caggaaaata tttccaagaa tgaacaagcc taatttgtta tctgcactaa aaagcagctg
     8761 gatagcataa taaggattca gtgcacggat aactgtccag tcttgactga agttcattaa
     8821 tcccattacg cctaaaaaag taaaccaagc gaacatgatt ggtccgaatg cttttccgac
     8881 aatatctgta ccaaagcgtt ggaccatgaa taaaacaaaa ataataacta aagtgataat
     8941 gacgatcacg ttctggttat taccgaaccg gtcaaaaaac tgcggaattc ctcgcaagcc
     9001 ttcaatcgca gtcgttaccg tcacagcagg ggtcaatacc ccatctgcta gtaaggcagc
     9061 tcctccgatc attgcaggaa tgatcaaata tttcccacct tttcggacaa gtgtgtagag
     9121 tgagaaaatt ccaccttcac catggttatc tgcattcaat gcaatcacga catatttgat
     9181 tgttgtcagt agagtcaatg tccaaaaaat caatgagact gatccgataa caaaatcagg
     9241 attgattcct gacaatccgc cattatcttc aacaatcgat ttcataacgt aaagcggact
     9301 tgtcccgatg tctccgtaga cgactcccat cgctacaagc aggccagcca ttgatatctt
     9361 tttggtattg tgcgttgttg ccacgttttt ccctcatttc ttgttatatg gatatccttt
     9421 aggtaagctt gaatgataga tgatattctt atccatgaca cccgctttcc taaattgctt
     9481 ctaattatcc aagtaacaca ctgaagtgtc aacttatttg aataaaatta ttctttcttt
     9541 ggacgttctc tgatacgtct tgccacaaat gaataaagag caaggcaaaa aattgcaccc
     9601 aataatgctg gtatcaaata aaaaccgccg agttccggtc ccagtggtcc tagtaaaaat
     9661 tcgccgagcc aactacctaa aaaaccgata atgatatttc cagatacgcc tcccgggact
     9721 tcctttccta aaattgcgcc agctatcaaa cctaatatac cgccgataaa taacgaccat
     9781 aaaaaattca gcatctcctt tccctccttt atccatattt ctcactttta ttttacgctt
     9841 tattcagaag gactccaaaa atatgcgcca agaaactcca gaaaaaaaga agttgtaaca
     9901 aaagtgttca gcttatttcc gtagaagctg cttctggaac accgtgaatc agaggttgtg
     9961 aaatcagcgg tttgacctga gtattagaga aacaaacgga aaaatagttc ctcatatttt
    10021 gccgtttttt gagctaatat cgagggacag ctgattgaac atcgtttatt ggagaggttg
    10081 taaaaaagct gttctgcatc aagtaataag aacagccaag taaaaacagc tcctaatgtt
    10141 tttaacttgg ctggacttat taccgcagat gcaagctttt gaacaccgtt tattcgaaaa
    10201 aaaaggactg tgacacggct tttgtcacag tccccttttt tcgaataatt attgtccccc
    10261 tgtcaccttc acgatcacaa gtacattatt cctatgaatt aaattatttt tcttcatttt
    10321 tcgttgaacc atcttcgttc aacattgctt ttcttgacag atttacgcgt ccttgtttat
    10381 cgatttcagt tactttcaca aggatctcat cacctagttt aacaacatct tcgactttat
    10441 tgacacgatc gtttgctaat tgggaaatat ggacaagtcc atcttttcct ttgatcaagt
    10501 tgacgaatgc accgaatttt tcgatacgga caactttccc tagataaact tcaccaactt
    10561 tgacttcttt ggtcaaatct tcgatgatct tgatagcttt tttgatcatt tctgcatcag
    10621 ctgaagcaat acttactttt ccatcttgat cgatatcgat tttcacacca gtttcatcga
    10681 tgattccgtt gatcgtatcg ccgcctttac cgataacatc tttgatttta gcaggttcga
    10741 tctggatcat ttcgattttt ggtgcatatt ggcttaattc ttcacgtgga gcagcaatcg
    10801 ttgaagtcaa ttcttctaag atttccatac gtgcttgttt tgcttgagtt aatgcttcag
    10861 ttaggatttg ttctgtgatt ccttgaatct tgatatccat ctgtaaagca gtgataccat
    10921 cttttgtacc ggcaacttta aagtccatat cgccaagatg atcttccagc ccttggatat
    10981 cagttaggat cgtatagttt tcaccatcag aaacaagtcc catcgcaata ccggcgactg
    11041 gcgctttgat tggtacacct gcatccatca atgctaatgt gccagcacag atacttgctt
    11101 gggaagaaga accatttgat tccaatactt ctgctactaa acggatcgta taaggaaatt
    11161 cttcttctga agggattact tgtgctaacg cacgttcacc taatgcgcca tgtccgattt
    11221 cccgacgccc tggagagcct gcacgtcctg tagaaccaac agaaaattga gggaaattgt
    11281 agtggtggat gaatcgtttg ctgacttcca cccctaaacc atcaatgatt tggtgctctc
    11341 ctagaggtgc gagtgtacaa gctgataaag cttgtgtttg tcctcgtgtg aacaaacctg
    11401 atccatgtac acgtggcaat aagctgacct ctgatgacaa tggacggatt tcatccaatt
    11461 tacgcccgtc aggacggatc ttatcgatgg tgatcaattc acgtacgaca tctttttcaa
    11521 gatcttctgt gatttgttta acttctttca acaagtgatc ttcatcttca tgacctgcaa
    11581 atttctcagc ataagcttcg cggatatcga tcttcacctg ctcgatatta tcttcgcgag
    11641 caagtttttc ttcagtcatt actgctgctt tcattgtagc gtaagaagca tcaaagattt
    11701 cttttttcaa tacttcatca acttgcagta aagtcacttc cattttttct ttccctactg
    11761 cttgaacgat ttcttcttgg aaagcaacta actctttgat agcgtcaaaa ccaaacagca
    11821 atgcaccaag catgtcttct tctgaaactt ctttcgcgcc gctttcaacc atattgatgg
    11881 cttgtttcgt tccggcaaca gtcaattcga tatctgtttg ttctgcttgt tctactgttg
    11941 gattcaagac gtactcgcca tttacacgac caacttctac gcctgcgatt gggccgtcaa
    12001 atgggatatc tgagattgat agtgctaaag aagaacctag cattgctgcc atagctggcg
    12061 agcagtctgt ttctacactc atcacgatgt tcgttacttg gacttcatta cggaagcctt
    12121 ctgcaaacat cgggcgaatt ggacggtcga tcaaacgggc agtcaatgtt gcttccgtac
    12181 ttggacggcc ttctcgtttg atgaaacctc cagggatttt ccctgctgca tacatttttt
    12241 cttcataatt gatcgttaat gggaaaaagt ctgtatcttt tgcttcttta gaggccacag
    12301 ctgcacttaa gactactgta tctccataac ggactaaaac ggctccgttt gcttgttttg
    12361 ctagctgacc gacttcgatt tgtaagggac ggccgcccca tgtcgttttg aatacttgtt
    12421 tttctgacat aacttctcct tttccttctc gtgaaagcaa gacgctacta aacaaatgaa
    12481 aactgccgaa agccgtcttt tgagcagctt tcatttggtt agtaggagtc catctagctt
    12541 gatcacggaa ttttacttaa ttgatatacg agtaaaaaaa gtgagattca tgtgaatccc
    12601 actctttttg actaaaatta acgacgcaag cctaaacgtt tgatcaattc gcggtaacgt
    12661 tgaacgtcag ttttacgtaa gtaagctaac aagttacggc ggtgaccaac ttttttcatt
    12721 aggccgcggt atgaatgatg gtcttttttg tgcacgcgtg catgttcatt caagtggttg
    12781 atttcttcag ttaatacagc gatttgtact tctggagaac cagtatcccc ttcatggcga
    12841 gcgtattcgt tgatgatttc attcttgcgt tcttttgaaa ttgccatttc tttcacctct
    12901 ttcgattatt cccctgcgac tgagtaaaac gttggtgatt cgcttaacca agtggcaggt
    12961 catgtgccta gagcacacag ctatacttta cctgaaaccg ggttgaaaat caagtagtta
    13021 atcattaaga aaaggtagtt ttcaaacaat cttactacta cttttccatt tttgtggtaa
    13081 actataatgc gaaaatagac ttgaaacaca gtcttttaag aaaggggtac atattccatg
    13141 attacaatgg atgatatcat tcgtgaagga aatccgacct tacgcgaagt tgcaaaagaa
    13201 gtttctcttc cattaagcga agaagatatc tctttaggaa aagagatgct tgagttctta
    13261 aaaaacagcc aagatccaat caaagctgaa gaactacact tacgaggcgg tgttggctta
    13321 gctgctcctc aattagatat ttctaaaaga atcattgctg ttcacgtacc aagtcctgac
    13381 ccagaggcag atggaccttc tctaagtact gttatgtata atcctaaaat tttgagccat
    13441 tctgttcaag atgcttgttt aggggaaggt gaaggctgtt tatctgttga tcgagaagta
    13501 ccaggatatg ttgttcgcca tgccaaaatc actgtgtctt attatgatat gaatggtgaa
    13561 aaacacaaga ttcgtttgaa gaattatgaa tcgatcgtcg ttcaacatga aatcgaccat
    13621 atcaacggtg tgatgttcta tgaccacatc aacgatcaaa atccatttgc actaaaagaa
    13681 ggcgtattgg tgatcgagta gagaattggc aggttccttc gatactatgc tacaagaaag
    13741 ctttataaaa aaggggagtg ctcaaaagct gcacttccct tttttatgtt tctccactaa
    13801 tcgaaattta gatagacatc tagaaatcgc aattccaaaa aattctgtgt attggatacg
    13861 catcttttct tattttttct tatttcttcc atatgggtgt ttatctcaga gatgatagaa
    13921 tagtttctag gataaaaagt agcagctacg atgttatcct tcgtagagga ttcctgcttc
    13981 agctagtttt tgtttgatgt ttttcagcat atgcttttct gggtagcgga tcgtatgcag
    14041 atggatgccg cctgttaatt cggataacaa agtagcatta cttttttgat aacgtctcat
    14101 aaaggaatcg atatcttgtg gcgttttgat gtgcaaagtt cctgctaact caccgtaaag
    14161 gggatgttcc acaattacat caatgatttc accaccattt tcaacgatta gtctcagttc
    14221 ttcttctgtt tgatcttttc catgctggac agcgatttta ctgatgtgcc cagtattggt
    14281 ttcttctgtt tcgaggatat aacctcttgc tgttgccacg atacttttac ctgcagctcg
    14341 tagtaaagca atatcgccta caatgatctg acggctgact ccaaaagttt tcgcaaactt
    14401 gctagcactc actggttttt ctgtatttgc caaggtttgc atgatttgtt ttcgccgtgt
    14461 ctctccttcg atcacactta ttcctccttc attttgtttt ggtattcgcg cgagtgtttc
    14521 atcaaatcaa catacgtgtc tgttattgtt tccttatatc ccttattttt cagcagacta
    14581 acaactttat ccaatacttg ctgctctctt tttgcatcat aaactgcttg gttttcttct
    14641 tttttcactt gtcctatttt agttaccgta tccattcttt tttctaataa agcaaccaac
    14701 tctcgatcga tcatatcgat cttatgacgt aatgtttcaa gagactcttc tgttagttct
    14761 tcctctactg tcttgatgat acgagcagga tttcctgcaa tcactacatt gtcgggaaaa
    14821 gatttggtca caaccgaacc tgcgccgact actacgttgt cccctagagt gacacccggc
    14881 gtgacgataa ctcctccgcc taaccaaaca ttattaccga ttttaatggg ttttgcgtac
    14941 tccagaccgc tgttacgttt cactggatgt agtggatgcg tcgccgtgta aagctggaca
    15001 ttcggagcga acatgcagtt atcaccgatt tcaatcgtgc tgacatctaa aaatgtacaa
    15061 ttgaaatttg cataaaaatt ctccccaaca aatatattat atccgtaatc aaaattgata
    15121 actggctcca tatagatttt tttccctgta cggccaaaag tctctttcaa caattgggat
    15181 cgcagttccg ctgattctgc ttggttgatg atttggcttt gacttcttgc aaacatacgg
    15241 tcggcaacca gctcaggatc attggcaaaa taaagctcgc ctgcaatcat tttttctttt
    15301 tcggttttga attcagtcat aatctgctcc taattcttgt atttttttga aaacaaccgc
    15361 tccgtcttct tgaataaacg tataaggctc cgctaaataa acaggcgttt gattgattac
    15421 taagattttg gctgacggct ggcgaaactg taccagatca caaaacggat gaacttgaaa
    15481 actcgttcca acaatgacga tcagctctgc ttggctgacg gcataagccg cctgctccat
    15541 gactccatct tgaaaccctt caccatataa cacgatgtct gggcgtattt gtcctccgca
    15601 tgcttgatgt ttgtcgctgt gaagatattc tttccagtct accgtttgtt gacattttcg
    15661 acaatgacat tgatacagac tcccatgaaa attgacgagt tgcgggcttt tagcctttgc
    15721 gtgcaaaccg tcgatgtttt gggaaacaac ccaaacattt ttttctttcg ctagatgtgc
    15781 tatttccaaa tgaatgatat tgggttttgc ttcaggatga taaatctttt tgacaaattg
    15841 atagaattta tccggttcat tcaccattgc ttgatgactc agcaagtatt ccggctgctc
    15901 catcccgtgg tagattcctg acaaagatcg atagtctggc actccagaag gtgtggatac
    15961 ccctgcaccg gtcaaaaatg taatttgctg ataagctaat atctcttttg ctgcttcgtc
    16021 tactgttaat tgtttcatgt tttgtcacct cactttccat tatagcccat actcgaacaa
    16081 atttattgtt gaaaagtcag aaaaatggga ataaaaaagt gttatgggca tttgagcaat
    16141 ttatcacaat gttcactgac aaaagaatga aaacgtgtta caatactgct gtataaaagt
    16201 gaggtgaatc gatatgttac cattctttat ttattggggc gttattctgg cttgtatcgc
    16261 ctggttagcg ttaagcgttt atttctctgt tttttatctt gtacgcaaag aaaatggaaa
    16321 tctttgggct tttgctttat tcaacgtgat tgccgcaatt gttttagcca ttacattagc
    16381 cgtatatcga acatggggct ggggaatcac ccaatactca agtttgattt atctaatatt
    16441 agccatttat ggcgtcgttg ttcttttgca agcgatccta ggacgtgagc caaagaaagc
    16501 ggcagcttaa atgatcgaga tggaactgga cacaggaaat tttctgttct agttcttttt
    16561 ttattgtatt acatacattt ttgtgtataa ttatactatc gtttgcaatg gatagatgat
    16621 tcacattttg attgtttttt cggtaaaagt aaagatttct atatttatca gtattttttc
    16681 aaaaaccagc agttatagat tgacaaagcc tctcgagtat cgtaaacttt ttttgtataa
    16741 ataactgaat acgagatgcc tcaatcaatg aggtagaggt cgcgagaatc attaaccctg
    16801 tggagtgaag caaacatgga gaagcaggaa tagggaggat cgccgaaatg tgcacttttt
    16861 tgcttggagt gtatgttggg acgcaagtta agagcttgcg gactgtctta gcagtgatgc
    16921 taagttgcgc tatgttttgt gagaggttta tcaccttatg gaattttagc ggccttttta
    16981 tatctataaa tcggtcgctt tttatttttt cagataaagc tttaccgcat ttcatctaga
    17041 ccgctcgtgt atcatataat cagaaaggga gaaaaaaatg aaaaaaaata tggtttcagt
    17101 tgccgtacta tttgcttttg tcttctcact attcagtgtg ggatctctgg caaatgcaga
    17161 tgaaaaaaca ccgagcgatg agtttcgcgt aggtatggag gctgggtatg cacccttcaa
    17221 ctggtctcaa caaacagatg agaataatgc cttgccaatt caaggccaaa atagttacgc
    17281 cggcggttat gatgttcaaa tcgctaaaaa agtagcagat ggtttaggga aaaaattagt
    17341 catcgtccaa acgaaatggg atggtctggc tcctgccctt caatcaggca agatcgacgc
    17401 gatcatcgcc ggaatgagcc ctactgctga acgacgaaaa gaaattgatt ttaccgatcc
    17461 ttattacgaa tcacaattag tagtagtagt tcaaaaagat agcaaatatg caaaagcaaa
    17521 aagtttagca gatctttctg gagcaaagat cactgctcag ttaaatacat tccactatac
    17581 tgtgatcgat cagataccag atgtgcagaa acaacaagca atggataatt tctcagcaat
    17641 gagaacagct ttagcttctg gaatgatcga tggttatgtc agcgaacgtc cggaaggtgt
    17701 aacggcaact agtgtgaaca aagacttgga aatgcttgaa ttcagcggtg cagatggctt
    17761 ccagacaaac ccggaagatg ttcagatttc tgttggtatg cgtaaaggcg acccggatat
    17821 ccaaaaagta aaccagattc tttctggcat ctctaacgat gaacgaacca aaattatgga
    17881 ccaagcagtc aaagatcagc ctgctgcaac tgatagtgaa gaaaaacctg gcatcatttc
    17941 tgatttcact acgatttgga aacaatacgg caatatgttc ttacgaggtg ctggacttac
    18001 cttgttcatc gcattgatcg ggacagttgt cggtactaca cttggattac tgattggtgt
    18061 cttccgttcg gtacctgaat caggaaatgc actgactcgc ttcttccaaa aaatcggaaa
    18121 tgcacttctt tctatctatg tcgaagtatt ccgcggaaca ccgatgatgg tacaagcaat
    18181 ggtcatcttc tacggtctgg cactcgcttt tggcatttca ttgaaccgaa cgattgccgc
    18241 tttgtttatt gtctctctca atactggagc ttacatgaca gagatcgttc gtggggggat
    18301 ttttgcagta gatgaagggc agttcgaagc tgcgcaagcc attggtatga cccatggcca
    18361 aacgatgaga aaagttgtta ttccacaagt tttacggaat atcttgccag caacaggaaa
    18421 tgagtttgtt atcaatatca aagatacagc agttttaagt gtaatcggcg tagctgattt
    18481 gttcttccaa ggaaactctg cttccggtgc gaatttccaa ttcttccaaa catttacgat
    18541 cgtcgggatc atctacttag tcatgacctt tacgatcacc agaatcctgc gggcggtaga
    18601 aaagaaaatc gatggtcctt cagcttatac caagcttgaa gaaatcgaca attcaaattt
    18661 gcaggaataa ggaggaagaa tcatgaatga aaaaattatt gaaatcaaac atctaagaaa
    18721 aagcttcggt gaaaatgaag tattgaaaga tatcagcgta acagtcaata aaggtgaagt
    18781 tgtgacgatc atcggttctt ccggttctgg taaatctact ttcttgcgct gtatcaattt
    18841 actggaaaaa ccaacaggcg gcgagatcat ttataatgga gaaaatgtat tagctcctaa
    18901 atataattta cctaaatatc gaacgaatct aggtatggtt ttccaatcct tcaacctgtt
    18961 caacaatatg aatgtcttgg aaaactgtat gtctggtcaa acaactgtcc tgaaacgaga
    19021 taaagaaact gccaaaaaag tagcaatcga aaatctggaa aaagttggta tggatcgtta
    19081 tatcgaagcc aaaccagcac aattatctgg tggacagaaa cagcgtgtcg caattgctcg
    19141 ggcattatca atgaatccag atgtattgct attcgacgaa cctacttcgg cgttagaccc
    19201 tgaaatggtt ggcgaagtgc ttaatacgat caaagactta gcacatactg gcttgacaat
    19261 gcttatcgtg acgcatgaga tggaatttgc aaaagatgta tctgaccgtg tcatttttat
    19321 ggataaaggt gtgattgcag aagaaggtac accagaagat atctttgtcc atccgaaaga
    19381 agaacgtaca aaagaattcc tttcacgtat tttaaatgct taggatcaat agctgattgg
    19441 gacaaagagc tgcggtgttt accgcagttc ttttttatga attactcata aaaggtaaat
    19501 ttctgaa
//
LOCUS       DAFENC010000051        18915 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.053, whole genome shotgun sequence.
ACCESSION   DAFENC010000051
VERSION     DAFENC010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18915
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.053"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(41..271)
                     /locus_tag="LP493_002317"
     CDS             complement(41..271)
                     /locus_tag="LP493_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134436.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            complement(707..1273)
                     /locus_tag="LP493_002318"
     CDS             complement(707..1273)
                     /locus_tag="LP493_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBL2134437.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1273..2229)
                     /locus_tag="LP493_002319"
     CDS             complement(1273..2229)
                     /locus_tag="LP493_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HBL2134438.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2229..2885)
                     /locus_tag="LP493_002320"
     CDS             complement(2229..2885)
                     /locus_tag="LP493_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBL2134439.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3255..5273
                     /locus_tag="LP493_002321"
     CDS             3255..5273
                     /locus_tag="LP493_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBL2134440.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    5343..5549
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5700..8114
                     /locus_tag="LP493_002322"
     CDS             5700..8114
                     /locus_tag="LP493_002322"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HBL2134441.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8462..10015
                     /locus_tag="LP493_002323"
     CDS             8462..10015
                     /locus_tag="LP493_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBL2134442.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10396..12180)
                     /locus_tag="LP493_002324"
     CDS             complement(10396..12180)
                     /locus_tag="LP493_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2134443.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12195..13916)
                     /locus_tag="LP493_002325"
     CDS             complement(12195..13916)
                     /locus_tag="LP493_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2134444.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            14016..14777
                     /locus_tag="LP493_002326"
     CDS             14016..14777
                     /locus_tag="LP493_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBL2134445.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            15744..16012
                     /locus_tag="LP493_002327"
                     /pseudo
     CDS             15744..16012
                     /locus_tag="LP493_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            16684..>18915
                     /locus_tag="LP493_002328"
     CDS             16684..>18915
                     /locus_tag="LP493_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134446.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
BASE COUNT         6215 a         3357 c         3785 g         5558 t
ORIGIN      
        1 aatttaaacc ataattgcgt ctcattaaaa agcataacca ttactccgat ctatttttaa
       61 acttagtctc tacctctaat atatatcgag tttttatttt gccttcagag aatactgttt
      121 ctttttttgc agttacaggt tgtttatttt cggaaaaagc taatatagct aaaattgaaa
      181 catccatctg gaatttatct tttttactgc tttgatcata aaagtctgca tattcatcac
      241 tgatattttt tctaataaat tcttccatca taaaaatcac ctcaaaacga ttatacgaac
      301 ttacgttctt gttgtaaagc gatatttgag gggcaaaaaa ggggcataat ttgactgata
      361 ttaagttagc tattgatata tgaatgacat acaaaaatat aaaatctttt aaaaatgctt
      421 atatatcaat gtttttgcca ttcttttata tatctgttat atgtcaaaaa aatgtgttca
      481 atttcaattt gtatttgaat aaagaggttg tgaaaaagct gtcctgcatc aagtaataag
      541 aacagccaat caaaaacagc ttctcatgtt tttgatttgg ttggacttat taccgcagat
      601 ataagctttt gagcaccgtg aataaagagg ttatgaaatc aacgctctaa cctgagtatt
      661 agagaaaaaa acgcaaaaca tatcatttat gttttgcgtt ttttatttat ctttttttct
      721 caatacaata taaaataggc ggctggttct tttggttgat aaaccgataa ttcagcacat
      781 tatatgtttc ctgtggcagt ttggaacaaa aagaatcaac catatccagt tctttttctc
      841 caccttcatg accatagtag acgacaagga tcaatcgtcc gcgaggcaca agtcgtttca
      901 atatttcttc catagctgtg cgtgtagtct ctggcatagt gatgattgct ttatcacttt
      961 ttgggagata ccctagattg aaaatccctg ctttgagatt ttgttgttca gctatcactt
     1021 ctcctaacgt ttcgtggcct tgtagaaaca atgagacacg ttcttctaac tgacgctgtt
     1081 ctagcctttc acgagtagca tcgattgctt gttgctggat atcaaaacta tagacatgac
     1141 cagtttttcc gatgtgttct gctagaaaaa ccgtatcgtg gccattgccc atcgttgcat
     1201 ctacgacgtg atcccctggt tgcaagattt cttgcagtaa tgtatggctg aaatgcaaag
     1261 cagtttgcaa catcagacgc tcaccttttt ccgtacatca tattttcctt ggaagctatc
     1321 tctgcgaaga agttcttcat caattgcatt caagacttcc cattttttca agctccacat
     1381 tggtccaatc aaggaatccc acggcgcatc ccctgtcaaa cgatggatga tgatctcttt
     1441 tggtatcatt tccagctggt cgcaaatgac attgacatag tcaggacggc tcattaattg
     1501 aaggcgacct tcatgatagt cccgcaacat tctcgttttg cgcatcagat gcatcaaatg
     1561 gagcttgatt ccttggatat ctgaatctaa aatggtgcgt ctgacatttt ctttcatcat
     1621 ttctaaactt tcgcctggta atccgttgat caaatgcgta caaacacgga tattatgttt
     1681 gcgtaattta gccacgccat ctaaataagt ttgataatca tgtgctcggt tgatcagttt
     1741 tgaagtttct tcaaaagttg tttgcaatcc aagttctacc cataaataca tccgctcgtt
     1801 cagttcagca aggtaatcaa ctacttcatc tggcagacaa tccggtcgtg taccgactga
     1861 taatcctacg acacctggta aattgactac ttgctcaaat cgttctttga ttatttcaac
     1921 tggcgcatgg gtgtttgtaa aattttggaa ataaacgatg tattgttgga catgaggcca
     1981 tttttgatgc atcatgtcga tttctttctg gaattggatt ggaagagggt cttcaggtgc
     2041 aacgatcatg tctcccgaac cagatacact gcaaaaagta caaccgccat gggcaacagt
     2101 cccatctcga ttcggacagt caaatcctcc atcgatcggc accttgaaaa ttttcccgcc
     2161 aaactcattt cgtaaagcgt aattccaaga atgatatctt ttatttcctt ctgaataagg
     2221 aaaagtcatt aaaagtcctt ctttctgtaa gagttatcta tttgttttct tttttctcta
     2281 tacactggat aagtcaggca cagccaagaa agactgagta agtaaccgcc gatgatatca
     2341 gtaggaaaat gaacgcccag ataaatgcgg cttatcccga cacttactat aataaacatc
     2401 atcagcaatt gaagcaatgt gcgtaaggtt cttttttgaa caaaagctgg aagcagaaat
     2461 agtaaagaac cgtaaagaat catactgcct gctgcatgtc cactagggaa actgtaactt
     2521 gtttcaacta ctaagtgcgc caatgaagga cgctctcgca tgaaaaatag tttgatcacc
     2581 gggttgatga ttccagcaat tacaataaat ccagaaacga accaaaatgt ttctgccctt
     2641 tttttcttat accacatcca taaagccgca caagcaaata aaatgatgac ggtaagagga
     2701 ttaccgaatt tagtcataaa gagttggtag ctgttcagat caggataaga agctctgaca
     2761 atgcctgtaa accactgatc gaaaccagaa agccacgaca gatggaactt tacgatccag
     2821 cccaaaatga aaaacaggac aagaaagaag ctaccagcca cctgaaatga tgttttatat
     2881 ttcatacaat tcctcctttg aagcaatgac ttattatagc atttttggtc cagcgaaaaa
     2941 aacggtaaag agataaaacc aatgtatgat tcctctttga ataaccaata ttcttataaa
     3001 aaaaataact gtaatcggaa agacattttt tggtaatgca aatgaaatgt tagggaaata
     3061 aaatcagtgt ttttcgaaat ccttttaaac aagaacgtag acgtaggaag aacttgaaaa
     3121 tgaacagaag ttgttcatta cggtaaatta caatatgatt acaaaaaaca acaaagctct
     3181 taaataactt ttaataaata ttaagagaag ttataattat taataataga taaattgaag
     3241 ttggaggata gaagatggaa aacattgcaa gaaaagaacg gagacgttta gaacagacca
     3301 aacgttttcg aaaagcaaaa cgaggggcag caatcgtggg aactgcgatg gtaggctgtt
     3361 ctgtcgctgc cccattagta cagccggttc ctgttcaagc ggatgaaaca cctgttcagt
     3421 tcggcgcaag aatcaataca gcggcattta tcacagaaat tgctacttat gctcaaccaa
     3481 tcgctcaagc caacgatcta tatgcatcag tgatgatcgc acaagcagtt gtagaaagcg
     3541 gttggggcag tagtgcgtta tctcaagcac cttattataa tctttttggg ataaaaggca
     3601 gctatcaagg acaaaccgtc tacatggata cgcttgaatt tttaaataat caatgggtaa
     3661 ataaaaagga gcctttccga caatatcctt cttttgctga atctttcaat gacaatgcct
     3721 atgtacttag aaatacttca tttggcaacg gttattacta tgccggtact tggaagagca
     3781 acacgaaatc ctatacagat gcgacagctt gtttgacagg gcgttatgcg actgatcctg
     3841 gttacgcagg caaattaaat aatatcatcg caacttacgg attgacccaa tatgatacac
     3901 cagctagcgg aaacgcaggc ggtggagcga ctacaggtgg caataatact ggaagtgcag
     3961 gtagtactgg cggttcaagc aattctggta atacaaactc aggttcagca acttcgacca
     4021 cttatactgt ccaatctggt gattctgttt ggggaatctc aaataaattc ggtatcacaa
     4081 tggatcaatt gatccaatgg aacaacatcc aaaacaattt catttatcca ggacaaaaac
     4141 tgacaatcaa aggtagccag gaaaatggct cttcgacgaa taattccggt aacaatacca
     4201 attcttcagg aaatgctggt acatcaaacg gaggacaaac aactggtgcg aaatacactg
     4261 ttcaatctgg tgattctgtt tggaagatct caaatgatca cggaattacg atggctcaat
     4321 tgattgaatg gaacaatatc aagaacaatt tcgtttatcc aggacaacag ctaatcgtat
     4381 caaatggcgg ttcttctaat gctggagcaa atactggctc aaatactggg aatacaagtg
     4441 gctctagttc gtccagctca agttcttcta atacagcttc aggaacgaaa tatacagtta
     4501 aagccggaga ctctgtttgg agcgtctcaa ataaatacgg aattacgatg gctcagctaa
     4561 tccaatggaa caatatccaa aataacttta tctacccagg acaacaactg actgtttcaa
     4621 acagtggatc aacaaacagc acgtcaggta atacaggttc gtcaaccaat acaaataaca
     4681 gcagttcagt taatactggc agcagttcgt ctcaaggcac ttataccgtg aaagcaggtg
     4741 aatctgtttg gagcgtggca aataaaaacg gcatcacgat ggatcagtta atcgaatgga
     4801 ataatatcaa aaacaacttc atttatccag gacagcaatt gatcgttaaa ggtggaactt
     4861 cggcaaatac aaatacaggt tcaactactt ctgcagcgaa accaaataca ccgaatacgt
     4921 ctgctacgac aagtacatca tccactggta atacgatgta taccgtgaaa gcgggcgagt
     4981 cagtttggag cgtagcgaac aaacatcata tcacgatgga tcagttaatc gaatggaata
     5041 atatcaaaaa taatttcatc tatccaggac agcaagtgat tgtgaagaaa ggttcatctc
     5101 aatcaacaaa ccaacaatca gttactggtt cgaaaaccta tactgtgaaa tctggagaat
     5161 ctgtttggag tgttgctgac agtcatggaa ttacaatggc tcaactaatc gaatggaaca
     5221 atattaagaa caactttatt tatccaggtc aaacgttgat tgtagctaaa taaaatagct
     5281 gttcgaagaa ataacgattg aattccacaa aaatatttgt tactataagg ctacttaaat
     5341 atgacaacac ttgaaaagga agtagtaaaa agactgaagt ttcagagagc gcatggctgg
     5401 tgagaatgtg cacggatgct tttgaactcg cctttgagtt gcccttgctg aatacccgag
     5461 taagcaagcg gcggtgacgg ccgttacaac gttcgaggcc ttttcactaa ggtaaaatta
     5521 ggtggtaccg cgtagattac gtcctataaa aagagcaatc tttttatagg atttttttat
     5581 ttcttttgtg aagtttgaga aaacaaagca aaaggaaata aaaataaaca gattctgccg
     5641 gttttttcgt tatatttata atagaaacaa gtgttttcaa tagaacagga ggacagcaaa
     5701 tgagttacaa tcataaagaa attgagaaaa aatggcaaaa atactgggca aaaacgaata
     5761 ctttcaacac ccatgatgat cctgaaaagc caaaatttta cgcactggat atgtttccct
     5821 atccatccgg tcaagggcta catgtagggc atcctgaagg ttatacggca acggatatcc
     5881 tttcacgtgt gaaaagaagt caaggataca acgtgctgca tccaatgggg tgggatgcat
     5941 tcggtctgcc tgctgaacaa tatgcgctag atacaggaaa cgatccagct gagtttaccc
     6001 aaaaaaatat cgaaacattc cgacgccaaa tcaattcttt aggatttagt tatgactgga
     6061 atcgcgaagt gaatacaact gatccggagt attataaatg gacacaatgg atctttacga
     6121 agctttatga aaaaggtcta gcttatgaag cagaagtagc ggtaaactgg gtacctgaat
     6181 taggaacagt tatttcaaat gaagaagtga tcgatgggaa aagtgaacgt ggtggctatg
     6241 atgtagtcag aaaaccaatg cgccaatgga tgctgaaaat cactgcttat gctgatcgct
     6301 tattggatga tctagaatta gttgattggc cagaaagcat taaagaaatg caaagaaatt
     6361 ggatcggtcg ttcagtagga gcaaatattg aatttaaagt ggctggtacg gataaatcct
     6421 ataccgtatt tacgacacga ccagatactc tattcggtgc aacttactcg gttcttgcac
     6481 ctgaactaga tcttgttaga gaaattacga cccctgaaca aaaagctgct gtagaagctt
     6541 atatcgaaga gacagctaaa aaatcagatc taaagagaac ggatcttgca aaagaaaaaa
     6601 caggagtatt tactggtgct tatgcaatca atccagttaa tggcaaggaa atcccaatct
     6661 ggatcgccga ttatgtatta tcttcatacg gcacaggagc catcatggct gttccagcac
     6721 atgatgaacg tgactttgaa ttcgctcaaa ctttcggact agaaattctt ccagttatcg
     6781 aaggtggaga tgttgaaaaa gctgcttaca cagaagatgg tacgcacatc aactctgaat
     6841 ttctagacgg catgaacaaa caagaagcaa tcgataaaat gaatgaatgg ctagaagaaa
     6901 atggcgtagg gaaaaaagaa gtcagctatc gcttacgtga ctggctattc tcccgtcaac
     6961 gttactgggg tgaaccaatc ccaatcatcc attgggagga cggaacagtc acagctgtcc
     7021 cagaagaaga gctaccatta cggttgccta agacaaaaaa catcaagcca agcggtactg
     7081 gagaatctcc attagcaaat atcgaggagt gggtcaatgt cgttgatcct gtaacaggta
     7141 aaaaaggccg tcgcgaaacg aatacaatgc cacaatgggc aggaagctca tggtattacc
     7201 tgcgttatat cgaccctcat aacaaaaaag aactagcaga ttatgaaaag ttgaagcgtt
     7261 ggctaccagt tgacatctac attggtggag cagaacatgc ggtacttcat ttactatatg
     7321 cacgattctg gcataaattc ttatacgata tcggtgttgt tcctacaaaa gaaccattcc
     7381 aaaaactata caatcaagga atgatcttag gcgaaaacaa cgaaaaaatg tcaaaatctc
     7441 gtggtaatgt agtcaatcct gatgatgtgg tcgaaactta cggtgcagat acactgcgca
     7501 tgtacgaaat gttcatgggg ccattagatg cttcgattgc ttggagcgaa aatggcttag
     7561 aaggaagccg taaattcttg gatcgtgtat ggcgtttgat cgttgatgag aacaataaaa
     7621 tgcgtgaccg tatcactaca ttgaatgatg gcaagcttga taaagtgtat catcaaacag
     7681 tgaaaaaagt gacagaagac tatgaaaatc ttcatttcaa tacagcaatc tcccaattga
     7741 tggtctttat caatgaagcc tataaagtgg acgctctgcc ttatgaatat atcgaaggat
     7801 ttgttcaact actcgcaccg attgctcctc acatgggtga agaactatgg gcaatccttg
     7861 gaaatgatgg tggtatttct tacgcaccat ggccaacata cgatgaagca gcacttgttg
     7921 aagacgaagt agaagttgtt ttccaagtaa acggtaaagt tcgtgcgaaa agcaatgttc
     7981 cccgagactt aggaaaagat gagctagaaa aagcagcatt agccaatgaa atagtgcaag
     8041 aatatattga aggcaaaaca gtcagaaaag ttattgcggt accaaacaag ttagtcaata
     8101 tcgttgctaa ttaattggct ctttgtcaat aaggactgat gagttgtgca aaatcaaatc
     8161 tgggccagaa tgaacttcat tctgtctcag attttttgtt atttcaaatt gattaattga
     8221 ttgatcaaaa aggttttgat tttcatgttc tcaaacacgt tcaatgtctt tttcttctga
     8281 atggtcttgt aagagatctc tgtaatcatc aaatttttgt ctattaatct tagtattttt
     8341 tgatgtataa actacctgaa attgagagta cataccaaat tcataaattt tttattagtg
     8401 ggactagtga ttgtatggat tttgacgcat aatgaatgaa gtatgagaaa aggagagaca
     8461 aatggatcaa gaactattta ttatcgaagt attatcagct aaacaaaaaa ttatcgagaa
     8521 agcgaaaaaa agagcgaaaa gaataatgtt caagctttta agcttagtat ttttctctgg
     8581 tttgcttttt ttcggagctg tatcgttcct atatcgccat atgagtgcag tagtccgttc
     8641 agctgaaggg atgcaaaaat taaataattt gtatcacttt tcgtggggag ttggcggaat
     8701 aacaattgtt gtgcttattg tttttcttct acttatttgg ctccgttacc atcaattgtc
     8761 gcgtcatttc gatcaatggc ttagtcaaag agcacaacag tttttacata ataaaccaac
     8821 ttctcaagat gatgactatc tttattttga gaagacttcg acgagtcaag cttttcggat
     8881 acaaaaaagt gattgccagt tattgctgag atcacttgat gatttaccta tctacttagg
     8941 cgaaagcaaa tcaaaattcg gaatgaacac attccatatt tttttactag aaaacgaacc
     9001 cagatgggaa aaaagccagt cttcgcctgg tggatacctg acaactaaga tgagtacatt
     9061 agtcactggt tttttcctca ttcttttagc tggaacaatc tattatggga gatacactca
     9121 gccaaaaatg tcttctcata taaatgctgc ttctcacatg acaatgaact caactaacga
     9181 tacgcatata caaaagacaa atgaagggtt gttagctgat cctaagcaaa aggtaaattt
     9241 gacaacacaa aagataaatg atctcaaact tgatacagag acgcactctc tctatatgac
     9301 aacagatagt ggtgctaatt gggtatttgt gccgattgat tcgcaatggt tgcgttttgg
     9361 cgaatacacc ctgacaacgg ggctgattcc tgaaggttat tggatggaca acacatatga
     9421 tatttccgcc gatttctcat ggtttatcta ttcttctggg gatgatgtac gtctgctgac
     9481 ttcaagagat aatggtaaaa catggcaaac gtctattatc acccaatcag ttcagccgat
     9541 acgttatcga aaagcggtat tttatggcaa cgatggtcta tttatctgta catcagccag
     9601 tgggatgtct gcagaaactt tgtacattta cactactatg gatggcggaa tcacttggat
     9661 aaaaagtgga agtacaatga tcaatcagcc agtacaaaat gtcagcttcg ttacaacttc
     9721 tttaggtttt gtttcgacac gtgaaagttt gttttataca aacaacggag gacgctcatt
     9781 caaagaatca gttctgtcga ttccggaaaa ctatcagaca ggggggatag atctttttca
     9841 atcaccaaat gaagttactc aaataagcgc gaatacgtta gagacaaaat tttatttgtt
     9901 gaaaaaagga ccaatcgatg cagggaaaat gtttgcctgc ctcttccgtt caactgataa
     9961 cggggaaaca tggcaattcg ttcagcaact atcgcaagta gaacaaggag attaaagaag
    10021 agagattgtg agcctgacgt tcagcaccga gtcacaagaa acaaattcaa aaaacagctt
    10081 ctcatatttg ttgaatagtg taactcgtga ttcggagttg acaagagcaa caagaagcga
    10141 ttttgaagta tagcttctcg tattttacaa gatcgtgtct tattgccgat aggttgtctc
    10201 ttgaacaccg tttattcgta aaaagggatt gtgacaagtc ttttgtcact acttaccgaa
    10261 cgaaactgaa ggagctatcc aaaaagtatc attagtatta ttctttgtgt ttctagtggc
    10321 accactagta catttaaaaa agctatcgat catggactaa tcatacatga tcgatagctt
    10381 tttagataat gtttgttacg ctatctgaaa ttgactatta taaagactgg cataaagcgt
    10441 tggtgattgg agtagttcag aatgtgttcc tttttcgacg atatcgccat tcttcattac
    10501 aaggatcatg tctgcatttt caatcgttga caaacggtgt gcaatcacaa aacttgtcct
    10561 atcttttgtc acagcttcca ttgcttgctg aatcaatgct tctgttcgtg tatctacgct
    10621 agaagttgct tcatctaaaa taacgacagg aggattcgct agaatgactc gagcaattgt
    10681 caataattgt tgctgtcctt gagataacgt gccgttttcg ctagaaatga tcgtatcata
    10741 tccgtctggc agtgttcgaa taaagtgatc acattgtgcg atttcagccg cttcgataat
    10801 ttgttctctt gtggcatcca ttttcccgta ggcgatatta tcagctaccg ttccttcaaa
    10861 cagccaggta ttttgtaaaa ccatcccaaa agaacgacgt agttctccac gtgaaagctt
    10921 ggtaatatca agaccgtcga attcgatctt tcctttattc agttcataaa aacgcatcag
    10981 cagattgact aaagtcgttt ttcctgcacc agttggacca acgatcgcta ccgtttgttt
    11041 tggctttact gaaaaatcga cttgattcat caatatttta tctgatgtgt aaccaaactg
    11101 tacatttttg aaagctattt ttcctttcgg ttgttctaaa agtcttgcat ctggaaggtc
    11161 tggaatttca tctgtttcat ctaatatctc aaatatccta tcgattgctg ccattgcgga
    11221 ttggatcgag ttgatcacat aagaagcggt agaaattggt tcagaaatct gattgatgta
    11281 ctgaagataa gcttgtaaga agccgatcgt cacaccacct gatagaacaa gcatagcacc
    11341 gaataccgca cttatgatga aggcgagttg attaatgaaa cgaatggccg gatagatagc
    11401 acagttcata aattgagcac gtttaaaagc gttgtattgc tttttattta cttcgtgtat
    11461 agcagcttct gcatgagctt gctgattgaa tgttttgacc actagattac cagctaagat
    11521 ttcttccatt cgattattta aaacacccag ttcatactga ttctgttcag aaatctgttt
    11581 gtttttgttc gcaatcttag ttgtaacaat tgaactgcca acgatcagca ataagacgag
    11641 caaagtaagc ttgctttcga tataaaacag catcagacca gcagcagcta ttgttacgac
    11701 agaagtaaaa aattgattga tacctgtcaa taacacttga gaaagttgat tgagaccggt
    11761 agttgtccga ctaatgatgt cacctacttg atgattgtca aaaaacgaca tcggtaatgt
    11821 tttgaatttt tttgtgattt cttttcgcac cctcaatgtg atcttttcgc ttaacgctgc
    11881 cattgtccgt tcctgaataa atgaagtgat gctgcttaag actgaacagc cgatcagcaa
    11941 taagacaggg aacaacaatg cttgtttgat atcactgaaa gaaagctgtc caatacctgt
    12001 ttttcttatt tctgataaga gatcatcgat cccgattccc atgatcaagg gcatggctac
    12061 gactaatagg ttcccgaata aactgcatag aaacaatccg taaaaatatt tatgttcagg
    12121 tttgatcatt ttccaaaaac gtatcaaagc acgcgtgttc aacgtttttt tcttttccat
    12181 cgtatccctt ctttctatat tccttgtgat tttgcaaact cctgataagt ttggcaatta
    12241 gacagtagtt cttcatgagt accttgtcca acgatttttc cttcatctaa aacaatgatg
    12301 ttatctgctt gttggattgt actgaggcgt tgagcaacaa tcacgagagt tttctccgac
    12361 atgtgtttat gaagggctgc tcttaatgct gcatctgttt tatagtctaa agcggagaaa
    12421 ctatcatcga atacatagat ctctgctggt ttgatcaacg ctcgagcaat acatatccgc
    12481 tgtttctggc cccctgaata attagaaccg ccttgagcaa caaagctgtc caatccgtca
    12541 ggaagggtgt ccactagttc ttctaattga gcgatcttga tcgctttaga caactcttct
    12601 gttgaggcat attcatttcc catctgcaag ttgcttaaaa ttgtcccgct gaataagaaa
    12661 gccttctgag ggacataact gatgtgggag cggatctgtt cttgagtcat ttgagtaaga
    12721 ggaataccac caagggttac ttttcctatc gtagggtcac taagtctcaa gagaagtttc
    12781 gccaaactac tttttccaga tccggtcccg ccaacgatcg ctgttgtttt tcctttaggt
    12841 attgtgaaat caatatcttc tagaactgga tcagagattt cagtatattt aaatgtgaca
    12901 tgttcaaaag cagctgcatt tgtctgatca aaggttggtt cagctactgt tttgatcgtc
    12961 tcttcctcaa tttcgatctc tgcttgcagt atttcttcta tccgtcgtaa tgaggcaaac
    13021 gatttaggga taatgaccaa taccatagct gcgatcatca agtaagcaag tgtcagcata
    13081 gagtattcga ctacagcagt cacgacaccg atttgtaatg ctccttctgc tacaagattt
    13141 ccgccaaacc acaaaataga agcataaacg attcccatga gcaaaaaagc aattggagtg
    13201 acccaagcaa atattcggtt cactttgatc atttgattag catagtcagc aaagctctta
    13261 ttcgttcgct tttcttcata tgattgatta tcaaaggcac ggatcatatt aatcccagta
    13321 aagaattctc tcaatgtgat ggtgatccga tccatttttg gctggatact caaagataaa
    13381 ggtgcccctc gtttcatcag tcgataaaca atccatacat aaaaaacaac agagatcaat
    13441 gtaacccatg ttagtaatag agaataacga aacatcatga gaatggtgaa aacgcaaata
    13501 accggtgctg gtaagatcat ttggcaaaat aaaacaatca tttgctggac attatcgaca
    13561 tcattcgtca ttcttgtcaa aagagatcca gaactaaaac gactgatatc cttcattgac
    13621 agctgttgga atttacggaa atatttctcc cgcgtttgga atccaaacct agcggaagcc
    13681 aatgctgaaa agtaactaga ggcaactgca gcgattgttc ctagaaacgc tacaagcagc
    13741 atttcaactc caattttttt tataactgag gcttcgccac ttgctatacc tgtgtcgatc
    13801 agctttgcta ctaattttgg tacacctaat gtaccggcga tttctaaaca gatcatcaca
    13861 aaggtaagga gagcgagtcc tttgtttttc tgtaagaatg tttttaagat agacatatta
    13921 ttcctccttt tttcctgata cttttcgatt ctataccttc aagtaacttg aaggtcaata
    13981 gaaaaaagaa taaactgaaa aagaggtgag aaaaaatgaa aaaaatgtat acgattggcc
    14041 aagtatcgga actatttgat ttgccaaaat caacgatccg ctattgggat gaacaaggat
    14101 taatccgttc aagtagacaa gaagagaatg attatcgatt gtttgatatc gatgatattt
    14161 ttatgcttta tgatatcgtt ttttatagaa aattagatat accgatcaaa cagatgaaga
    14221 atttatatgg aaaaacattg acggagttat atgagacact tgatgaaaca gaaagaagaa
    14281 tccataaaga actggtggtg atgaaacaaa aacaaaaaga gataagggag caaaaaaaac
    14341 agttgaaatt gatgatcgat acaaacgagg aagaatttcc tgtagaagag atcccttttg
    14401 actgtatgat ctcaacggag tttgaagata ttgtggaaat caaaaaattt ctacctaact
    14461 attcaagctt tgggatgatg agtatgccag cttccagttc acagacgatg tatggatttt
    14521 ttatcgaccc tagtgaagta catttattta ctcaagacgt gatttgggag aaaaaagata
    14581 cggctgttta tcgtcgattc ttattgaaat ccgagatgaa ccatgcggaa cgtaataata
    14641 ttttagaaat cagagaaaga atgtatgaaa aaggatggaa aacaggagaa gtgatcggcc
    14701 agtatctatt gacgaatacg gatgaaaaca atatcagaac tgaatattat catgcatgga
    14761 tagaaatgaa aaaataggaa atatgtgttt aagataactc gaaaatgatg gttgttttag
    14821 ttataaagaa aaattttctg gttcgattac gggtttaatg tgggggatta ttagtcgtgg
    14881 atagatagaa ttttagtttt ttagaggaaa tatgtcttta aaaatggaat ggttgcaatt
    14941 cttagcgata tatacgatgt aattgtcctc ttaaaaaagt atggaaaaat aattgtattg
    15001 ggtgttatgt ataattcatg gtgaactgag actaatgaga agaaaaattc atattgttat
    15061 gagtgagatt gtatcagatg agaatgataa attaaatagg tgcataaaag cattacactt
    15121 aaaatacatt gttgcttaca ttattacaat atgttaataa ggcaaaaata aatagatgga
    15181 ttgaataaac atatttttta atcaaatagt ccctactgtg actttcctca gctatcggtg
    15241 atactaccga tagcattttt ttgcttataa aataattata agtatttaga gatttttctt
    15301 ctaacattct tcaaacaaga aaaatcacaa aggttattgt tatttttata tattcttttt
    15361 aagaatgatt gtttttttat agaaatttta aaaaataaaa cacgttattg atggatagtt
    15421 agtttgttat ttggtaatat tatagaagtt gactggtagt gatttatttt tcgtcgtttt
    15481 ataaaaatgt tattttttgg aaaaattcac aaatatgtaa cgaatgtttt tctggaattt
    15541 gctgtgttaa aaagcagtat gactaatata aatactattg tcatttatgc aattttttat
    15601 ggatagtaat tttagagggg aatcaatgaa ggaagaatag aagggaaaaa tagttgcaaa
    15661 tacgccagtt agcaaaaata gcaatacatc ttcaagcttt aaaattcgag agaatcatct
    15721 tggtagtgga atcaactaca acaaaaggat taaaccaatt aatagataga attaccaatg
    15781 gaaaaataga aaaggtagtt attctataca aaagttgttt aattcgcttc ggttatgaac
    15841 ttagtgaaac cctttgcaat atatggtaca gaatatagaa attattgaca ttacagaaaa
    15901 tgatgaagat ttaatacaga ttgtcactat ttgtagatac cttttacaag gaaaccgagc
    15961 caataaagct aagaagatga ttaaggagtt gatggaagac gatacaagtt aagaaagtga
    16021 aactacgccc aaataaagag caaaaagagt aattggacgt ggaaaatgca agaaatgaac
    16081 catcgattcg gtggacagtt tattagtaat gacggtttga gaacatccat gacgagaatg
    16141 aaggaacatc ctaaatgcgt ttagttgaac caagtgccaa ataatatggc caaataagcg
    16201 atcagttatc gatgaatccc aagtattcta aactatatat tcattttgat gctaagcatt
    16261 gatatatttt tttgggattg atgaaggtta accaatacag ggactcactg atgaaattct
    16321 agagtctgac cttggtatca acgatttagt gattgtttct aatggaaaag tataaaagta
    16381 tataagtaca ttaacaaaat aactattagg gttacgctcc agcttgtgca aggcactggc
    16441 aggaggaatc gtgaaatcat aattatggtt aagccacacg gacaactaaa agtcatacaa
    16501 agctatcgaa tcaatcaaca gaagacaatc ggcaatcatt agctttgttt acagcttaca
    16561 ttgcaacgct tgagttgaac cgaaaatacg agggaggtaa cgcagccatt ttgagttggg
    16621 gaatcttttt agaaaattat cgggtacctt gttgtttagt caaaattata agggggagta
    16681 atagtgagga acaaatttca taaactgtta agtatgtttc tagttatgct tattgtgatc
    16741 aatcaatttg ggaacataac ggttctagct gagtctttag cagaacagcc agagcgttcg
    16801 ctgacgatcg aagttgatca agaggaggct gctttgggtg agcagttcca gttgcgagtc
    16861 agaggaacac cagacctgct aaatgcattg gtcattgata agagtgagga tttgattgaa
    16921 ggggaagtga agcaactcaa tgattacgaa cgtctgatta cttattcttc ccagcattca
    16981 ggtaaatacg aattgaccgc aagaagcggt gatattcaat caaatacggt ctcaatagaa
    17041 atcagtgtac cagaagaaag cacaagtgag tcttttaatg taccagaaga aagcacaagt
    17101 gaatctttta atataccaga agaaagctta agtgaatctt ttaatgaagc cagatcatct
    17161 gagccatcta taacgcagga atctcagatt gaaagacaag aggagctctt gaattatgac
    17221 atcggcatct ctgctgagcg ccccactttg ccgagcaggc atacacaaac gttaaaggga
    17281 tacattcaag gaggcgctgg cgatattctt gaagaatatg gggagatggt cgtacgagtt
    17341 cctagagcat cgattggctt aattgagttc attagagtgg aggtcgctga tgattcacct
    17401 ttaaagccac tggcatttta ccaagaaggc acagacgttg tttttccatt tacctttgat
    17461 tatgaaggat taaatgaagc cgctcagtcg tatacattca gtatcacgtt tgaagttgct
    17521 ttctttcaat caggcggtac tgagccaaat aatgactttc aagtgagtct tacttatgct
    17581 gagcgagcag caaacacgga attttcaatt acgcctattc cttcatcaag acccattttt
    17641 tcgaaattat actatggctc tagagaaatc gacagccaag gaaatcttgg gaatctgctg
    17701 attgacgggc aagacgtgac caacagtaat aaatttattt tgcaggtaaa ttatgaagga
    17761 tcacgaaaag acggtgtagt ggttaccgat gtactaccgc aaggaacaac tttggcaccg
    17821 aatccgacta catggagttc cactggaaat agagaaccta tttcaggtgg ggttcggatc
    17881 gcagaagtaa cgaatccagg tgaagcaaac gttagaactc attatgtttc cgaggaattt
    17941 gtggacaaag tatcttttaa taaggaaacg aatacacttg ttgtggactt tggtaatcta
    18001 gcagagggtc aatcgtattt tattgaatat gctcttgaag tgaccgatgt cgacttgttc
    18061 aatgaaggaa gacaagagga tgggttttct cggaatcgag cgagtatgac ctacaataat
    18121 caggtaatga gccgagacta ccgcttgaga atccctgaaa gtaatcttcc ggcaatctct
    18181 ttaagaaaaa gtgtggacaa aaatgttatc aatctcaatg aaaatgaact aacgtatact
    18241 ctgcatgtct cgatgttttc tggaacaaga aatacgcttg ttattgaaga tgttttggaa
    18301 gaaggcatgg aatttgtgtc atttctatca gatattccct ctttcattga tgccgaagtc
    18361 aataatggaa tagttcgttt cagtgcgaat aatacgattg gtggtccgac aagttttacc
    18421 ctctctttta aggtcaatgt agaggcgtat gcggtcggcg atcaaatttt aaactttgca
    18481 acgcttgtga atagtgacaa tcgattgaat acgagtactg taagaacaag gaaaatcgat
    18541 gggcgtatta aagtaattaa aactgatgag aatggccaaa ggctggcagg agcaaaattt
    18601 gaaattttat caagcgattc acaagtgata caagaaggta taacggcaga aaacggagaa
    18661 tttttaagtg aaccgcttcc tgtaggtagc tatcaagtcc gagaaacaga agcaccggaa
    18721 gggtatcttt tagatgcgac ggtacatgat gtttttataa atgaatactc catagaagaa
    18781 gtgacgttaa ccattgaaaa catccttgat acgggtggtg ttgaactaat taaacatgct
    18841 gaaggcagtg gtgaagtcct tcaaggagct gtttttgagt tacagaaccg agaaggagaa
    18901 acgctacaaa ccggt
//
LOCUS       DAFENC010000052        17550 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.054, whole genome shotgun sequence.
ACCESSION   DAFENC010000052
VERSION     DAFENC010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17550
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.054"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            278..787
                     /locus_tag="LP493_002329"
     CDS             278..787
                     /locus_tag="LP493_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL2134447.1"
                     /translation="MVQGIERGVYVVDKIQFNQVIEEFIKVNNLMTHIQKRPIRITND
                     LKLSTSMIHLIDVIGNYPETSITELADRLGVTKGAVSQQIPTLEKMNLISISQKKGNK
                     KTKLVSLTKYGRKVYESHNYLHEELYSSINEALESFSPDQISTIKQILEKVSYTINEY
                     QVSLTRKED"
     gene            880..2042
                     /locus_tag="LP493_002330"
     CDS             join(880..1156,1156..2042)
                     /locus_tag="LP493_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBL2134448.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLIPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
     gene            2322..3302
                     /locus_tag="LP493_002331"
     CDS             2322..3302
                     /locus_tag="LP493_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2134449.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
     gene            3424..4842
                     /locus_tag="LP493_002332"
     CDS             3424..4842
                     /locus_tag="LP493_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HBL2134450.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            4913..6382
                     /locus_tag="LP493_002333"
     CDS             4913..6382
                     /locus_tag="LP493_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL2134451.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            6392..6859
                     /locus_tag="LP493_002334"
     CDS             6392..6859
                     /locus_tag="LP493_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL2134452.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            6895..7767
                     /locus_tag="LP493_002335"
     CDS             6895..7767
                     /locus_tag="LP493_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL2134453.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFIKSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            7848..10382
                     /locus_tag="LP493_002336"
     CDS             7848..10382
                     /locus_tag="LP493_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL2134454.1"
                     /translation="MKKKMKDEVLEYIKNNLKYYDFSAQDIAMKFCIKRNVASHYLNQ
                     LFSDGKLLKNDSVRPVMFKYNQQKPKDCFSKFIGADISLKSTIDKCKATVMYPPNGLP
                     LIIKGNSGVGKSFLASLIYQYALDRKVIHNDAKFVVVNCADYANNPELLSAVLFGYKK
                     GAFTGAEKDTAGMLSSANGGYLFLDEVHNLSAENQEKLFLLMDSQKYRKLGESVQWEY
                     ANVRLILATTEDKNTSLLATFRRRIPAEITLPDYNNRSTSEKIQLLFEFLKDEAITID
                     SKIFCSIELFTDLLSKTFEGNVGELRNEIKLLCAEGYLGNKRKSSIYLGDKLDSGFWI
                     DPEISIDLKKMFLKSLSEIDLIELFQNHISIEESMSQLRDRILKECAGSSEYNYLESD
                     EFIALRNYVVNKISPIIDSTGLCLLDEFLADISLFIMFIDVIEETSRNFLLSKFRKFR
                     MKNDKQKLLANEIWSSLEVEESKQELLLKWILFLVKKFYVKIPETHCLIVMHGKITAS
                     AIARETNKLLNTYVYEAFDMPIEGETSDLINLINNFCKSIDTTNGLILLVDMGSLEQM
                     YEKIESNVIGDLVILNNVSTALAIECGIQVCQKKPISHFYQMDFDSFQVKVQYYKGLS
                     QKKNVIVSCLSGEGISEKVKDILKRYLDNQVEILIFDFNALKKIAKEKDTMIFKNTIC
                     VLSTTEFYIQGIDCLNLENLINGNQTLEKLNKYMDSDSCEFCLNELVKLFTIEGASTK
                     LRFLDSKKVFNEIEKVLYLYEKYYDVKIPSFLRINLFLHLSGMIERIMIGDGITNEHL
                     KEGAQLFDTFLNVSKDFFSEIKDIYCIEIPKGEYELIYTIFEQTIF"
     gene            10538..11311
                     /locus_tag="LP493_002337"
     CDS             10538..11311
                     /locus_tag="LP493_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2134455.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
     gene            11304..12095
                     /locus_tag="LP493_002338"
     CDS             11304..12095
                     /locus_tag="LP493_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL2134456.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            12105..12596
                     /locus_tag="LP493_002339"
     CDS             12105..12596
                     /locus_tag="LP493_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2134457.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            12614..13024
                     /locus_tag="LP493_002340"
     CDS             12614..13024
                     /locus_tag="LP493_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBL2134458.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            13028..14428
                     /locus_tag="LP493_002341"
     CDS             13028..14428
                     /locus_tag="LP493_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HBL2134459.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            14451..14825
                     /locus_tag="LP493_002342"
     CDS             14451..14825
                     /locus_tag="LP493_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBL2134460.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
     gene            15314..15508
                     /locus_tag="LP493_002343"
     CDS             15314..15508
                     /locus_tag="LP493_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134461.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
     gene            15498..15851
                     /gene="tnpB"
                     /locus_tag="LP493_002344"
     CDS             15498..15851
                     /gene="tnpB"
                     /locus_tag="LP493_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HBL2134462.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            15953..17500
                     /locus_tag="LP493_002345"
     CDS             15953..17500
                     /locus_tag="LP493_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBL2134463.1"
                     /translation="METTDTLLQLLQEAHKTNQTQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKTDKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
BASE COUNT         6063 a         2550 c         3525 g         5412 t
ORIGIN      
        1 ttttttattt gtctcgctta attatacaaa cggcgtgata aaaaacgaga aatgaattat
       61 aggtttagac ctttatcatt tctcgtttta ttttattgta tcaaggctct atcataagtg
      121 gtaaaatcta cttttaaatc acatgtaatc attgataagt ccagtgtttt agcggataat
      181 cagcttttta tttatttttt cttataaatt tgataaatag aaattagtat agccctaaac
      241 aaattatttg tgttttattg tttagggcta tactatattg gtacaaggaa tagaaagagg
      301 tgtttatgtg gttgataaaa ttcagtttaa tcaagttata gaagaattca tcaaagtaaa
      361 taatttaatg acccatattc aaaaacgacc aatcagaata actaatgatc taaaactcag
      421 tacgagtatg attcatttga ttgatgtgat tggaaattat cctgaaacta gtattacgga
      481 attagctgat cgattaggcg ttaccaaagg agctgtatcc caacagattc ccactttaga
      541 gaaaatgaat cttataagca tttctcaaaa aaaaggaaat aagaaaacta aacttgtatc
      601 gttaacaaaa tatggtcgaa aggtgtacga atcacataat tatttacatg aagagcttta
      661 tagctcaata aatgaagcgt tagaatcatt ctcaccagac caaatttcaa ccattaaaca
      721 gattctagaa aaagtatctt atacaatcaa tgaatatcaa gtaagtctga caagaaagga
      781 agattgacat gaaaaaaatg atttttgaat cggctacact agactagaca gaaaaaataa
      841 ggtgtgtaaa ataaatgaaa acacactgga ggaattttta tgtcaagacg tcaacgtaga
      901 acctattcaa aagaattcaa acaacaagtc gtcgatcttt atctcgcagg aaagccccga
      961 gctgaaatca ttcgagatta tgagctgact acctcggcct ttgataagtg ggtcaagcaa
     1021 gcgcaaacta ctggctcgtt tcaggaaaaa gataacttga tccctgaaca agtagaacta
     1081 attgcattac gaaagaaaaa taaacagctt gaaatggaga atgacatttt aaagcaagcg
     1141 gcgctgatat tgggacgaaa agacaagtaa ttgataccaa taagcacaaa tactcaatat
     1201 cagcgatgtg taaagtgtta aacatctctt gccaaaccta ttattatcaa gccaaaccag
     1261 ttgaagatga atcagaactg gaagaactcg ttcaagaaga atttattcgc aatcgaaaag
     1321 cttatggtac caggaagctg aagcagtgct tggccaatct aggtcttcaa gtgagtcaac
     1381 gcagaatcgg ccgtatgatg aaacagcgtg gcttgcgttc aacatacaca ttggctcatt
     1441 tcaaattcca ttcttctact tgtaacgaag ccaagaccgc caatattcta gacggaacct
     1501 tcctacagga aaagtcatta gaagcgattg taaccgacct tacctatgtt cgtgttggga
     1561 agaaatggca gtatatctgc ctgattcttg atttgtttaa tcgagaaatc atcggctatt
     1621 catgcgggga gaagaaagat gcgacgttag tcaaggaagc ttttgcaaag attccgtact
     1681 cgttgaataa tgtacaactt tttcacacgg atcgtggaaa agaattcgat aaccagacga
     1741 ttgacgaaat tttatgggcc tttaatatca cgcgttcctt aagcaaaaaa ggctgcccct
     1801 atgataacgc cgttgcagaa tccacctata aatctgtcaa agtagaattc gttcatcaat
     1861 accgctttga gacattggct aatttgcgat tagagctatt tgattacgtc cattggtgga
     1921 ataccatccg gctgcacggc acgttaggct atgagacacc gatcagtttt cgacagcaga
     1981 gattggcgca gcgaatcctt gataatgagc tcggatgtga taccggtggc gaggcacctt
     2041 aattatttga atgagcttct gccttagaga atcagattcg aggaggctcg ttgtcaaggg
     2101 cagtcggaac accagcagca agcttacgca ataccttata atttttgtca aaaaaagtgt
     2161 tgccattcca catatatctt taaacagcta ttgccagata aaaataaatg atattatata
     2221 tataaatact tatccgaaaa ggggaatgag agagtcaagg ttcttggaat gtcgaatagt
     2281 cgagtaggta gattttctat ctacaacctt gttgtttaaa aatgaaaaaa attggaatta
     2341 gagaagttgc gaaagaggca aatgtttctc ctacgactgt gtcgagggta ttgaatgatc
     2401 gtggatattt gagtgaggaa acaaaaagaa aagtttttga tgccatgaaa aaattagaat
     2461 actatcctaa tgaactggcg agagcacttt ttaaaaacga aacatatacc gtaggtttga
     2521 tttttcctac aattactaat ccatttcacg ctgagttaat tcaagatatc gagttcgagc
     2581 tttccagcag gggatataaa gtgttgctgt gcaatagctt aaacaatcca acaaaagaaa
     2641 aagagtactt gacgatgttg agaaagaatc aggttgatgg aattatagta ggaacgcaca
     2701 ataaagatat tgcggattat gatattccag ggctacctat tgtagcgatt gatagaagtc
     2761 ttggtgaaaa tacagttaca gtatcttgtg ataattacag gggtggggaa ttagctactc
     2821 aactacttgt aaatcatggc tgtcagaata tactgtgtat tcggggagat agtaagataa
     2881 agctacccgc gaatagtagg actttagcat ataaagatgt tttgaataaa ttcatgctgg
     2941 aaccgttagt cctagaagta ccatttgtaa aagaaatcaa tgaaaaaaat gaaataatta
     3001 agacatatct ggaaactcat ccaaatattg acggggtttt tgcaggagat gatttattgg
     3061 cttctttggc gattaacaac ttaggaagtt cgggcaaaag agttccaaaa gaggttaaag
     3121 tgattggatt tgatggagct caacaaacat tgatttataa tccagaatta tcaactattc
     3181 aacagcctat agatcaaata tctaaagtag cagtaaaaaa attattgaat atgattaagg
     3241 gcgaaaagga gacggatgaa ctttcacttc cagtaaagct cataaaaaaa aatacagcat
     3301 aagttaaatc ggcgaaaaat tccttcgtcg atttaaaaat atttttatga aacgggttga
     3361 catatgaaac gggttgacat atattagttg tgaagataaa aaccttttca ctggaggaag
     3421 aaaatggaga aattattaat taaaagcaat aatcatcaac tttactacca acctaaggat
     3481 gtttgggtcg gagatgttat gccttacggg aaagaaggaa aattctttat ttatcatcaa
     3541 cgtgatacta gaaatccagt tccttttgga gaaccgtttg gctgggcttt agcaactacg
     3601 aaagattttg ttcattttga agactttggg gaatctcttt taagagggga tgacaatgag
     3661 agagaccagt ttatctacgc tggttctgta tttgaggcaa atggaaaggt tcacgcattt
     3721 tatacagggt ataatcgtga attcttagcg cagggaaaga catctcaagt gttgcttcat
     3781 gctgagagtg atgattttgt tcattgggaa aaatcagaaa cagcattgga gttagaacca
     3841 caagaagggt atgatattcg aaactggaga gatccatttg tcgtttggga tgatgaaaaa
     3901 gaagaatatt tgctaatttt aggggcgcga aagggtcagg ataaacatct acaaaccgga
     3961 cgtttagtgg aatttacatc aaaagattta actaattggg aattcaaagg tgatttttgg
     4021 gctccgggat tgtataccat gtttgaaatg ccagaacttt tcaagattgg tgactggtgg
     4081 tatcttgtct attcagaata ctcagatgga aataaaatac tctatcgaat gagtcaaagt
     4141 ttggaaggtc cttggattaa gcctaaagat gaagcttttg atggacgggc ttattatgca
     4201 ggtagaacag cttatgatgg aaaacgtcga gtcctatttg gatgggtacc aacaaaagat
     4261 caagaaaatg ataaaaacaa ttatttatgg ggaggtactt tggttcctca tgaagtctat
     4321 caaaaagagg atttttcact tggggtaaaa cccatagacg aagtgtggaa tgcattcata
     4381 aatttacatg atattgccga tgtagagata gaaacagcag acacaagaga agaagtaacg
     4441 cttgtcaaaa atagtggaac tttgtttaat ttagaaacaa caatttcatt tgatgagaat
     4501 cttagtgact tttcactgag attatataaa aaccttgaga cagatgaatc ttacgaatat
     4561 cgcttcaatt tagatgaggg gcgtcttaca tttgataaaa acccttgtta cccttggttt
     4621 caatatatgg ataaaggact tattagacct atatctttaa agcctaacca atcttataaa
     4681 ctaaaagtga ttgttgatga caatataatg acactttata ttgatggaat cgctcttaac
     4741 gctcgtgtac atggttgttt tggtcaagca attactatta cagcaacaaa tggatcaatg
     4801 actgcaataa ataccaagtt ttcaaatgaa ataaagaaat aataaacgtc aatcatgtgg
     4861 caggtctgaa aatcaaacat gacctgtcac atttaaaagg gaggataaat gaatggacta
     4921 caaaaaaatt gccgaagatg tattggaaaa cgttggagga aaagagaata tctcaagcgc
     4981 tacacactgc attactcgtt tacgtttaat tcttaaagac aaaagcaaag cgaatatgga
     5041 aatgcttgag gaaatagaag gtgcaaaagg tgttcttttc aatagtggac agttacaagt
     5101 aattttcgga acaggtataa ttgaaaaggt ttacaaagag ttcgttgaat tgacaggagc
     5161 taaggaagta tccgtttctg aaatgaaaga cgaaggagtc aataattcag gaaatagact
     5221 tcaacgagct tttaaagttt tctcggatat ctttattccg atcattccag cttttattgg
     5281 ggcagcaatg gttttaggaa ttcgttcgtt gattaccact cctggaatgt ttggaatgga
     5341 tggctcattc gctgatcaca atgtattcct aaatgattta tccaaatttc tgggtattat
     5401 tgcaaccaca tttgattatt taccagtttt agttatgtat tctgcaacaa aacgttttgg
     5461 cggaaaccct attttaggat tacttgtagg atttgttatg attcatccag gactagccaa
     5521 tcggaatgat ttcgtcatgg gaactataaa gcctgattat tggcatttat ttggattaag
     5581 cattccagca gttgcgtttc aagggggtgt ttttccagca attttgactt cttggttttt
     5641 agcaaaagtt gagaaaatta caaataaata ttctcctcaa gtacttgctt acattttagt
     5701 cccaactgtg acaattgttc ttgccaactt tgcactattt ttagtgtttg gtccattggg
     5761 gaattttatc ggtaatgttt taggtggaat cattgatttc ctatatatga agatgggtgc
     5821 ctttggtgct tttgtttttg caggcgcgtt acaaccatta gttgtaacag gaacacaaca
     5881 tgctattcaa ggtattgagg caaacttagt cgcaacaact ggattcaatt atatccaacc
     5941 tatttggtca gtttcaatta ttgcccaagg tggcggttgt attggtatgt atttactctt
     6001 taagaaaaaa tctaaagata gagatattgc gatttcaagc tttattccaa cactggtagg
     6061 tattactgaa ccggctatct ttgctgttaa tttgaaatat tcaatcgttc cttttgtttg
     6121 ctcgtttatt ggtgctggtt ttggtggagc atttatgaaa atttttgatg taaaagccat
     6181 tggacaagga ttgactgtat tgccaggtct gactattgct aatccagttc ttccttatat
     6241 atttggtaat ctcatagcat tcattttacc aatcattttt attctcgctt atgataaata
     6301 taaagtgttt atccctgaag ctaaacaccg taaatttgca gaaaaaactg actcaaaaaa
     6361 attgccagtt caagtaaagt gagatgagag catgttaaat ttttttagaa aaaatgaaat
     6421 aagcgttgta gcacctgcaa ccggtgtttt tgaaaaactg gagaaattaa gtgatccagt
     6481 cttttcaaaa ggaatgatgg gacaaggatt tgcaattgat gcaaaaaacg aaacgattgt
     6541 atctccaatc gatggttttg tttcaagtat ttttcctaca aaacatgcct taggaataaa
     6601 aacaaaatca ggaattgaga tacttgttca tgtaggaata gatacagttg agctaaatgg
     6661 tgagggattt gatattaaag ttcaagaagg acaaaaagtt aaggctgggg atattcttat
     6721 gaccattaat tttgtagttt ttgaaaagaa tcacaagact aaagatgtca ttgttgtttt
     6781 tccagactac caagacgaaa ttttcattcc gaaacttgaa gaagtaaaac aaggacaaga
     6841 attgtttgtt cttggctaat gataagtaat taataataga atcgaggaaa atgtatggtt
     6901 tttggggcta ttgaagctgg tggaacaaaa tttgtttgtg ccattggaga taaagatttg
     6961 aacatatttg aaaaagtcag ctttcccacg actacaccca aagaaacaat gaatttagtt
     7021 ttagattttt ttaatcatca taaagatgat ttagaaggta tcggagtggg atcgttcggt
     7081 cctattgata ttcattgtga atctaaaacg tatggcttca ttaaatcaac gccaaaactt
     7141 gcttggcagg attttgattt tattggaagt ttaaaaaagc aacttaatat tccaactgct
     7201 tggacgactg atgtaaatgc ctcttgctat ggtgaatatg tttctggaaa tggcagaggc
     7261 ctttcaagtg ttgtttacta taccgtagga acgggcatag gaggtggcgc tatccaaaac
     7321 ggaaacttca ttgaaggttt tagtcatcca gaaatgggac atatgcttgt aaaacgacac
     7381 aataaagaca acttttctgg gacatgtcca ttccacggag actgtttaga gggcttagct
     7441 gctggtccgg caatcgaaag aagatcaggg aaaaagggac aagaagtgac tgaaaatgac
     7501 gttacttggg aaatagaagc ttattacatt gctcagtgtg catataatac aacattgatg
     7561 ttatcacctg atgtcattat atttggtggc ggagtaatga aacaaaaaca cttaaaaaag
     7621 aaagtacaag ataagtttat tgagttgatc aacggatatg tcgctattcc cgatgttgac
     7681 aattatatta tgacaccaaa attgttagat aattctggta ttgtaggttg tttagcttta
     7741 gcaagagacg ttaaagaaaa atcttaattt ggaaaaaaga tcgtctcgac tatttgtttg
     7801 gttgatgcga tctttttttc aattagtaat tgaagggacg cctaaaagtg aaaaaaaaaa
     7861 tgaaagatga agtattagag tatatcaaaa ataatttaaa gtattacgat ttttctgctc
     7921 aagatattgc aatgaaattt tgtattaaaa gaaatgtcgc ttcccactat ttgaatcagt
     7981 tattttcaga tggaaaatta ctaaagaatg attctgttag accagtaatg ttcaagtata
     8041 atcaacaaaa gccaaaagac tgcttttcta agtttattgg agcagacata tctttgaaat
     8101 ccactataga taaatgcaaa gctactgtaa tgtatccccc taatggcctc ccattaataa
     8161 taaaaggaaa cagtggcgtt ggaaaaagtt ttttagcaag tttgatctat cagtatgctc
     8221 ttgatagaaa agtaattcat aatgacgcaa aatttgttgt tgtgaattgt gcagattatg
     8281 caaataatcc agagctattg tcagcagttt tatttggata taaaaaagga gcctttactg
     8341 gggctgaaaa agatactgca gggatgctat cttctgctaa tggaggatac ctttttttag
     8401 atgaggttca caatctaagt gcagaaaacc aagagaaatt gtttcttctt atggattctc
     8461 aaaagtatcg taaacttggt gaaagtgtgc aatgggagta tgcaaatgtt cgccttatct
     8521 tagccacaac agaagataaa aatacctctt tgttagcaac ttttagaaga cgcatcccag
     8581 ctgaaatcac tctgccagat tacaataata gaagtacatc tgaaaaaatt caattattat
     8641 ttgaatttct taaagatgaa gcaattacga ttgattcaaa aatattttgt tcgattgaac
     8701 tttttactga tcttttatcg aaaacatttg aaggaaatgt tggagaattg aggaatgaaa
     8761 tcaagcttct ttgtgcagaa ggttatttag gaaataagag aaagtcttca atttatttag
     8821 gggacaaact agacagcggt ttttggatag atccagaaat tagtatagat ttaaaaaaaa
     8881 tgtttcttaa atcactttct gaaattgatt tgattgaact ttttcaaaat cacatttcaa
     8941 ttgaagaaag catgagtcaa ttaagagata gaatacttaa agagtgtgca ggttcttctg
     9001 agtataatta tttagaaagt gacgaattta tagcattaag aaactatgtt gttaataaaa
     9061 tatcaccaat tattgattcg acaggtctat gtttattaga tgaattcttg gcggatatca
     9121 gtctatttat aatgtttatt gatgtaattg aagaaacatc aagaaatttt ttgctgtcta
     9181 agttcagaaa atttcgtatg aaaaatgata aacaaaaatt attggcaaat gagatttgga
     9241 gtagtttaga agtcgaagaa agtaaacaag aacttttgtt gaaatggata ctttttcttg
     9301 taaagaagtt ctatgtgaaa ataccagaaa cccattgtct gatagttatg cacggtaaaa
     9361 taacagcttc tgcgatcgca agggaaacaa ataagttgct gaatacatat gtttatgagg
     9421 ctttcgatat gccaattgaa ggtgagacta gtgacttaat taacctaatc aacaattttt
     9481 gtaaaagtat agatacgacg aatggactca ttctgctagt tgatatggga tcattggaac
     9541 aaatgtatga aaaaattgaa tccaatgtaa taggtgattt ggtaatttta aacaatgttt
     9601 ctacagcttt agcgattgaa tgtgggattc aagtttgcca aaaaaagcca attagtcatt
     9661 tttaccagat ggattttgat tcgtttcaag ttaaagttca gtattataaa ggattatcac
     9721 aaaagaaaaa tgtaatagta tcttgtctct ctggtgaggg gatttctgaa aaagttaagg
     9781 atattttaaa acggtatctc gataatcaag tggagatttt gatttttgat tttaacgcat
     9841 taaagaaaat agcaaaggaa aaagatacta tgatttttaa gaatacaatt tgtgttcttt
     9901 caaccactga attttacatt caaggaatcg attgtttaaa tttagaaaat ctaattaatg
     9961 ggaatcaaac cttagaaaaa ttaaataagt atatggactc ggatagctgt gagttctgct
    10021 taaatgaatt agttaaactc tttactattg aaggcgctag tactaagctt cgctttttag
    10081 attccaaaaa agtattcaat gagatagaaa aagtactata tttgtatgaa aaatattacg
    10141 atgtcaaaat cccaagtttt ctgagaatta atctatttct acatctttct ggaatgattg
    10201 aacgaattat gattggtgat ggaataacaa atgaacattt gaaagaggga gcgcaactat
    10261 ttgatacttt tttaaatgta tcaaaagatt ttttttcaga aatcaaagat atttactgta
    10321 ttgaaatacc caaaggagag tatgagttaa tctatacaat ttttgagcag actattttct
    10381 aaatagcata ctagcgtcta aaaaaatgaa agggtgtcca aagtatattt agacgctcat
    10441 ttaattaata tttactgtat tttcccgctt tattggataa tgttagttgg cacagtaatt
    10501 gcttatataa aagtataaga agaaaggaga gaacaaaatg gcgttttggc aaacattttt
    10561 agttgtgttg tatggatttt tcattaactg ggataaggaa gggcccaaaa tcggaacctc
    10621 ccaacctgtc gttgcaggtt tcttgaccgg acttattatg ggagatattc aaactggact
    10681 ttatatcggt gggactttgc aattaatgac actaggtatt actagttttg gtggtgcatc
    10741 agtaccggat tatcaaacag cagcattgat cggtacttat ttagcaatct caactaacca
    10801 ggatgcttct ataggaataa ctttagcaat accggtagca atgttaattg tacaactaga
    10861 tgttctaaag tggtcaacaa acattttttt tcaacaaaag gcagaaaaat tcgcacaaaa
    10921 agaagattat caaaaattag agtggatgca atatttggca tcaattaata caagctttgt
    10981 atctggaatt cctgttttgt taactgtgat attaggccca acgttagtgg gaagtgcaat
    11041 caattatatt cctgaatggg ttaccggtgg tttaaaggta gcagggggac tattacctgc
    11101 tgttgggata ggaatgctac ttaaatattt acctacaaaa gattactttg cctatttgtt
    11161 agttggtttc gttttggcag tttatttcca aataccaatt ttagggattt cgttacttgg
    11221 cgctgcaatc gcactaatcg tatataaaaa tagatcaaat aatactcaag tagcaccagc
    11281 tgcaacagga ggttttgacg aagatgaata agaaactgac aaaaatcgac aaacaagtaa
    11341 ttttccggtg gattctcaat ggtgcaactt cattaaatta tgaaaaaatg gaagggttgg
    11401 gttatgcgta ttctatgctt ccttttatca aggacacata taaagatgat cctgaaggaa
    11461 tgaaacaatc cgttttagct cacttacaat tttttaacac tacgccgtat acagcgcctt
    11521 acattattgg tatgaatgtt ggaattgaaa aagaagaaaa aaataagtct ttggaagcag
    11581 taagtgctct gaaaacaggt ctaatgggtc ctttagcggg aattggagat agtgtatttg
    11641 tagttattcc atggactatt tttggagcaa ttgcagctaa tatggcattg gaaggtagtt
    11701 ttgttggaat tattttgtgg atactggcat caattttatt aaggattact gcttatcctt
    11761 tataccttgc tgggaaagaa tcgggtgcga gcctactaac tcaaattgaa acaaaattaa
    11821 agtctattac tgatgcagta tcaattttag ggttaatggt ggtcggtgca ctcattgcca
    11881 cagttgtaaa agtgaatgtt ggctttgaat ttaaacaagg cgacttaaca atgaccggaa
    11941 atgaaatctt tgatcaagtt atgcctggtt tattacctgc atgtgtagta gcaattgtgt
    12001 attatttgtt aggacgaaag gttaaaccag tttatgtaat tctattaatc ttagtagttt
    12061 ctattgcgtt aagagcgtta aatattttga agtaggtgtt gaatatggat gaaaaaatga
    12121 aaggtattat acatgttcgt attgatgatc gaatgattca tggacaagta gcaacacaat
    12181 ggacaaatca attgagtgct aacagaatta tggttattaa taatgaagta gccaatgatg
    12241 acgtaaaaaa agctgtagtt cgcctcgctg caccacctaa tgttagaact tcaataatta
    12301 caagggaagt agcagttaaa aatattcttt ctggtaaata tgaaggacaa aaagttctta
    12361 ttgttgcagt ttctccaatc gatgttaaat ttttgattga taacggttta ccaataacaa
    12421 gtgtaaacgt aggaaattta tcaagaagga atggaacaga acgcatccgt ccgacgataa
    12481 atattactga agaagagaga gaggctttta aagaactaat tagtgatgga gttgaagtga
    12541 cagtgataca aactcctaga gattcaaaag aatttttaaa ggattttatt tattaagaac
    12601 agaggatgag tggatggagt ttataattac atctcatgga aatattgcca ttggatttgt
    12661 agatacatta aaaatgtttt ttggcgataa tttaaattgt catgtggtaa cacttggaga
    12721 tgcaggcatt gaagaattcc gtgaaaacat tgaaaaaata gtttctcaag taaaaaatca
    12781 agaagttatg gtatttgctg acttgattgg tggaacacct ttcaacgaat ttgctaaaag
    12841 aagtgaagta tttcaaaatg ggtttcaact tcttggtggc atgaatttag gaattttgat
    12901 tgaggctgtc aatttgagat tacaaggaaa aaaaagcgat gatatcatcg aaaatctaag
    12961 aaatatgaat acaattgcgt gtcttgcaga tatgcaaaga catactaacg aagaggatga
    13021 gtgataaatg caaaaaattt tttacaagcc taaagatttt tggtttgggg attgcatgcc
    13081 tttttataaa gatggaactt tttatctatt tcatcaacga gatacgagaa atcctaaacc
    13141 tttaactgat ccttttgggt ggtcactagt tacaaccact gattttgtga aatttgaaga
    13201 atacggggaa gtaattcatc gtggtggcaa cgatgacatt gatcaataca tttacgctgg
    13261 aagtattgtc caaggaatca atgagtattt agctttgtat actggacata atcgcaaagc
    13321 taagttggat ggaaaaactt cagaagtgtt aatgattgca agttctaaag atttaattca
    13381 ttggaaaaag gatggcgaag cagcaaaact tgttcctcaa gaaggatatg ataagaatga
    13441 ttggcgcgat ccttttgcaa tttttgatca agatcatgga aaatacgttt tgatactagg
    13501 agctagaaaa ccagcaagta agaaaaagcc gacggggaga ttggtctatt ttgaatccga
    13561 agatttaaaa gattggaatt tcaaaggaga ctactgggct aataatgaat ttaacatgat
    13621 tgaaatgcct gatatatttg aaattgatgg aacgtggtat ttactttttt cagagtattg
    13681 tgaagataaa aagactaaat atcgagtcgg agcaggatta ttttcagatt ggaaatcacc
    13741 agtagacgaa gctttcgacg gaaaagccta ttatgcagca agaacagtcg gaactaatga
    13801 aactggccgt tttctaactg gctgggtggc aacaaaagaa ggggagaacg atcaaaataa
    13861 ctgggattgg ggcggtgcac ttgttccaca tcaaattatt caaaagacag acaaaactct
    13921 tggtgttaaa ctgcctgaaa aaataattga gaattttaaa gaaatcactc cattttcaag
    13981 ttttaagtta gagaaagaat ttggaaaaaa agaaagagta attgttccta aaatcgaaga
    14041 ttattttcta tttgaaacaa ctttgactat tacatcgtta acaaaggagt ttgctttaaa
    14101 attatttgta gatagtgata ctcaagaagg atacgaattt cgtatttcat tgattaataa
    14161 tcagcttact ttcggaaaaa ctccgaacta tccttggcct caaatgtttg ataaggggct
    14221 gcaacgacca ctatttttgg aaataggcaa agaatatgaa ctaaagttaa ttgttgatga
    14281 tacgatagct gttttatata ttgataatgt tgctttaagt actagaatgt atgataaagt
    14341 cggaacagca ttaagtatga ctgttacgga gggagcaatc aaggtagata aactagacta
    14401 ttcaataaat tatgaatgtg gattttaaaa caattgaagg gatgatgtaa gtgaaattaa
    14461 atggtttaca acatattgga attccaacaa aagattttgg agcttcaaaa atcttttatg
    14521 aatccttagg gtttagtctg attaatgaag aaatgaatgt gggaagtaaa gtcggctttt
    14581 tcgagttgaa tggaacgata atagaaatat gggaagataa aactactgag tgtagaggag
    14641 ccattgatca tctagcatta gatacggatg acatagatga ggtattcaat tcaattcaag
    14701 atttaggata tgaattatta gataaaaata ttatggaatt accgttctgg gaaaatggaa
    14761 tccgttactt taatttctac ggaccaaatc atgagattat agagataagc caaatgaaga
    14821 aataaataga taacgaagtg ctctaagttg gtatgaacga aaagtacttc attttttggt
    14881 atcagcattt caatagttta atgagaattt actatttcaa attaattcaa agtgacagta
    14941 ttttttactt atttggtttc aaattttgta atccttccta tttattggaa tacactccac
    15001 attttgtata caagtcatat catgttttag caaagctctt accaagcaaa gttataatga
    15061 tgttttccaa agtttgatct ttcgatggag gctaacacat attttttgca ggacagccaa
    15121 aattagatgt atagaataga gtctgtgagg cgtatagaca gtttattgtc tgtatgcctt
    15181 tttttatttt gaaaaatttt tagtattttt cgaaaaatgc tcactcctag agtaagcgcc
    15241 ccatagaaca gtaccttact aacaaatgca cctcaagata tacttgagct atcaagaagt
    15301 ctggaggttt tctatgtata aattaaatga gattgttcct gtccaattag gaaacgaaaa
    15361 gagtgcacca gaaaaaggta aacccgcggc tgccaagtta gcgatgcgca tcaaaagaga
    15421 gaatggttct gaagttttga tctataacgg tattaacaat tatattcttc aagctatttt
    15481 gaaagaactg ttgtccaatg ctttatgatt tacttcaaac caaacatatt tatattgtgt
    15541 gcggaaaaac agatttgcga aaaggaattg atggtcttgc cagtcttatt caacaagagt
    15601 atcaactcga gctttacgaa gatgccgttt ttttattttg cgggaaccgt caagaccgtt
    15661 tcaaacttct ctattgggac ggtgatggtt ttcttctctg ttataagcgg atagaaaacg
    15721 gcaagttaaa atggcctcgg acgaaagacg aagttcgaac cttaacgaac caacaggttc
    15781 gatggttgtt agaaggatta agtatcgatc aacctcgagc tattttgcca ggaaaaaaag
    15841 gagtttttta agctgggggg ttaacacaaa aaatgtgttg aacccctatt tcttgtgcgt
    15901 ttcttgtggt attctgtaac aaaatcagtt cgattcaagg tggtgaaaaa ttttggaaac
    15961 tacagatacg ttgcttcagt tgcttcaaga agcccataaa accaatcaaa cacaacaaca
    16021 aaccattcag aatcttacaa ctgaaatcca actattgaat gaaaaggtca attatttaac
    16081 caacaaatta tttggacgct ctaaagagac tctctttgaa gaaacgaatg ggcaattgaa
    16141 tctttttagt gatgaagaaa tttctgtaag tgttccagaa gcagctgcca ccattattcc
    16201 agtaaaagga catcaacgag ttgtaggaac gaaaacagac aaaatcaaac acttacctat
    16261 aacagagaaa gaacatctcc ttcctttgga agaacaattt tgtgaacatt gcggttcaca
    16321 gatgaaagat atcggacgga caaaagtacg agaagaaatt cgtttccatc aggctatgtt
    16381 ggattgtctc acccattatc aacataccta ttgttgtaaa agctgcgaaa aagaaggact
    16441 ttcttctttt aaaaaagcga tcgttcctaa acctttgatt tctaatagct taggttccaa
    16501 tagtttagtg gcggaaacga tccggatgaa atttggtcag aaagttcctg cctatcggca
    16561 agagaactat tggaaacaaa cacatgggtt ggatatttcg agagataata tcaccaattg
    16621 gcatattaaa gcagtgcaaa acgcgttaga ccctttagga gaacgattaa gagtctatct
    16681 taatcaagaa gagattctac acggggatga aacaagttat cgtgtgattg aaagtgccaa
    16741 aacagatacc tattactggc agttttgtac aggaaaagac agtcagcatc ccatcgttta
    16801 ttatcaccac gacgaaagtc gtgctggaga tgttccgaaa acttttctca aggagtttac
    16861 agggtattta cactgtgacg gctatagcgg gtataatgcc gtggaaagtg tacgacttgt
    16921 ctattgtttc gcgcatgttc ggcggaaatt tttcgaagca attccaaaag gaaagaaaaa
    16981 cacggatatt cccgcagctc aagcagtcaa acaattggat aaatggtttg tcctagaaaa
    17041 gaaatggaaa gacttttctc ctgagaagcg attaagctgt cggcaacaag aactgcgtcc
    17101 attatttatt gctttttatg agtggatggc aacgatagat cctgttgcaa aatccaagtt
    17161 ggatgcagcc gttcaatatg cgtgtaaact acgaagtggt tttgaaccta tttttgaaga
    17221 tggtcgttta gaactcacaa ataatcgtgc ggagcgaaat atcaaagagc tggtgatagg
    17281 acggaaaaat tggttgcatt ccacaagtct tgaaggagca cgaacttcag gaatcattct
    17341 gagtgtatat aaaacagcag aacttaacgg attgaatcct gtaaagtatc tagagtttct
    17401 atttgataag ataccaaatc ttcccgtact ttcagcagaa actttagatc aactgttgcc
    17461 ttggaacaag gatgtacaac aacatttttc tcgtaactaa aaacgccaaa cattcccgat
    17521 tctattctat aggtcgggtt atttgacgta
//
LOCUS       DAFENC010000053        17005 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.055, whole genome shotgun sequence.
ACCESSION   DAFENC010000053
VERSION     DAFENC010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17005
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.055"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..124)
                     /locus_tag="LP493_002346"
     CDS             complement(<1..124)
                     /locus_tag="LP493_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HBL2134464.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVF"
     gene            complement(228..539)
                     /locus_tag="LP493_002347"
     CDS             complement(228..539)
                     /locus_tag="LP493_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBL2134465.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(541..738)
                     /locus_tag="LP493_002348"
     CDS             complement(541..738)
                     /locus_tag="LP493_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HBL2134466.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1132..2859)
                     /locus_tag="LP493_002349"
     CDS             complement(1132..2859)
                     /locus_tag="LP493_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HBL2134467.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2852..4045)
                     /locus_tag="LP493_002350"
     CDS             complement(2852..4045)
                     /locus_tag="LP493_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HBL2134468.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4232..4876)
                     /locus_tag="LP493_002351"
     CDS             complement(4232..4876)
                     /locus_tag="LP493_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2134469.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4970..5104)
                     /locus_tag="LP493_002352"
     CDS             complement(4970..5104)
                     /locus_tag="LP493_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HBL2134470.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5106..7238)
                     /gene="feoB"
                     /locus_tag="LP493_002353"
     CDS             complement(5106..7238)
                     /gene="feoB"
                     /locus_tag="LP493_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBL2134471.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7235..7708)
                     /locus_tag="LP493_002354"
     CDS             complement(7235..7708)
                     /locus_tag="LP493_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBL2134472.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8109..8333
                     /gene="nrdH"
                     /locus_tag="LP493_002355"
     CDS             8109..8333
                     /gene="nrdH"
                     /locus_tag="LP493_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HBL2134473.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8492..10651
                     /gene="nrdE"
                     /locus_tag="LP493_002356"
     CDS             8492..10651
                     /gene="nrdE"
                     /locus_tag="LP493_002356"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HBL2134474.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10701..11666
                     /gene="nrdF"
                     /locus_tag="LP493_002357"
     CDS             10701..11666
                     /gene="nrdF"
                     /locus_tag="LP493_002357"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HBL2134475.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11755..12894)
                     /locus_tag="LP493_002358"
     CDS             complement(11755..12894)
                     /locus_tag="LP493_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBL2134476.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13203..13916)
                     /locus_tag="LP493_002359"
     CDS             complement(13203..13916)
                     /locus_tag="LP493_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBL2134477.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14170..14871)
                     /gene="nagB"
                     /locus_tag="LP493_002360"
     CDS             complement(14170..14871)
                     /gene="nagB"
                     /locus_tag="LP493_002360"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBL2134478.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15105..16637
                     /locus_tag="LP493_002361"
     CDS             15105..16637
                     /locus_tag="LP493_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBL2134479.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16828..>17005)
                     /locus_tag="LP493_002362"
     CDS             complement(16828..>17005)
                     /locus_tag="LP493_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2134480.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5278 a         3495 c         2909 g         5323 t
ORIGIN      
        1 aaaaaacaca ttccactaaa tttgatgccg gttttccttg aggttttgtt ccagcacctc
       61 ctttaatttt tttaagctct tgatctgaac attgtttagc atttagtcta tttttttctt
      121 ccattacgat tccccctaca aactataaat acttttatgt cactgattca atatacctat
      181 ttttctaatc aaaaaatttt gagacatatt taatattata agtatcatta aaattgagat
      241 ttatctccat aatctgctcg atataaacca tttattccag cagttcttcc aatttcactc
      301 aaatttctta ttaattcctc ttgatattca gtgaatctta ttttattagt ataagcagta
      361 aaatatagat aattcaccaa tctatttatt aaaggactgg gatctaattc atatttttgt
      421 ttttctaatt ttaaatatac cttttgtaaa acctcaagaa tatcagaata tttaggatct
      481 ttacttatag atatatcatt atataattca tgaacaattt gcttagcatt ttttttcatt
      541 ttagcacttc cctggaattg ctccacctaa aaaaccacct atagacattc ctgcaataca
      601 agtagttgcc ttggcccaat cgaccgtaca tttattttta gtgcaataca ctccatttcc
      661 ataatatttt ccactatgag tggtaccccc atagataagt tgtgtctctt taatagacaa
      721 aatttttaaa tgtttcataa tctaatcacc cctaaattaa tgtttttaga ctattattct
      781 aacattcatt aaatttcaaa aaacaattcc ttcttgaaac gtagcaaaat aattcctgaa
      841 taagaattta atcactttta agtatataaa ctatgtatat tctttaatat tttttgagaa
      901 tgcacttcgt acataataaa ctttaatcac attagtcttt catacctacg atcgatctct
      961 ttgactcgca cccataaatt cataatagtt tgtcggcgtc tttgaacgtt tcgaagatga
     1021 gctacgcatt ctcttttttt atagacaaaa aagatagaga cgaacatgga gcttccaaat
     1081 ttggatattt gatccaattt tggaagctcc atttatttcg tgtctgtctt tttatttttt
     1141 ccagctttcg actaattctt ggttctcttt gatccagtct tttgctgctt gctgtggatc
     1201 ttttccattg ttgatttcca acataacttt ttccatatct ttttctgacc aatggaaatt
     1261 gtctaatact ttgtaagctt ctggctggtc ttctttcaat ccttttcgaa ccatcgtatg
     1321 gatctgctct tcgcttccca ttccgttttc aggatcttct aagtatttca gatcatattt
     1381 ggcaaacatc caatgaggtg tccatcctgt aactacaatt ggttcgtgtt ttttgatcgc
     1441 ttgacctagt gcaacggtca ttgctcctga agaagatgtc tctactttcc agtctttcaa
     1501 gttgtcatat ttttggatcg tgttttcagc agccgtaact acaccagctc ctggctcgat
     1561 tcctatgatt ttcttacctg cctgatcggt taactcatcg atcgaattta catccatgta
     1621 ggctggcact gctaaaccaa cttttgctcc tgtcaaattg gcacctaggt cttcgacttg
     1681 atctttatat tgtgcatatt gtgaaccatg agttttaggt agccaagctg aaaccatggc
     1741 atctgactcg ccatttgaaa cagatttcca catgattgaa ttatctaatg gcgtcatcgt
     1801 tacatcatag cccatttgtt tcaatacttc accgactaca tttgttgaag caacttctgt
     1861 atcccattca acataagata agttgatacg ttttgtttct ttggcagatg aaaaactccc
     1921 tataccaatc gcacctaaga tcactactac tacagcacca atgatcagtc cttgacgttt
     1981 tttacttttc tgtgttgttg ctcctgcagc ttttttattg tttggctggt tcaaatgctg
     2041 tgtaaaacgg tcaatgatga ttgctaagat aactaatgca accccgttga caaatccatt
     2101 cccgacttgt gctctttgca atgctgataa tacgccgcgt cctaagccgg gtgcaccgat
     2161 catagaggca ataacgacca ttgaaagtga cagcattgtt gtttgattga tccctgccat
     2221 gatcgtactt ttagctaaag gcaattctag tttgaatagt ttttgacgac ttgtgctccc
     2281 gaatgaatca gaagcttcta ctaattcttt aggaacttgt cgaatcccta aattcgtaaa
     2341 acgaacggtt ggtggcagag caaagatgac tgaggcaaat acccctggaa ccatcccgat
     2401 accgaaaaat gcaactgctg gaatcaaata aacgaatcct ggcattgtct gcataaagtc
     2461 aaggatcggt ttgataatac tttgggcttt actgcttttt gccatcaaga tccctaatgg
     2521 taccccaatg atgatcgaga tcacactaga taaaagaaca agtgtgacag tattcatcaa
     2581 atcattccat agaccttggt tataaataaa ccatagaccg attaatgtga acaacgtaag
     2641 tcctggacgt ttcttagaaa taaagaaagc tgctaccgtc aataacaaga taaacaaagg
     2701 agctggaatc actaacagta aatttgtaat ccccgacatc actgcctgtc caatcgtttg
     2761 taaaaatgaa aataggccag aaaaagttgt cgtaaaccat tctgtgatat tttctaccca
     2821 gtttgccact ggtaattgat agttcaatag attattcatg ttcactcacc tcgcttgttt
     2881 ctgctaatgc ttcaatcaca ctacctcgga tgacgacacc ttttaatttt ccatcctcta
     2941 caactgcaag tggagtcggt gagtcataaa taatattgaa aatatcactt accaccatgt
     3001 ctttcccaat caccgtcaca ttttcatcta ggaagtcgat caatggacgt ttttgcttcc
     3061 tagcttctaa cgcttgatct gcagtgatga tccctttcag gtgtctcttt ctgtcaacag
     3121 ccatcagcat gctgacttct tcattacgca tccttgtcaa tgcaacgttt ggtccatcag
     3181 attcgatatt cgtcgtcaat gcaggtacca tgatgttttg agccgtaagc actttggaac
     3241 gatcgacttc ttccacaaat tcacgtacat aatcatttgc tggattggtc aatatttctt
     3301 cacctgttcc gatctgcatg atttcgccgt ctttcatcaa ggcgattctg tccccaatcc
     3361 gtaaagcttc attcaaatca tgggtaatga aaataatcgt tttttgaaca ttggcttgca
     3421 ggtccagtaa ttcgtcttgc atttctcgcc ggatcagcgg atcaagagcc gagaacgctt
     3481 cgtccatcag caagatctca ggatcatttg ctaaagctct ggctaggcca acccgttgtt
     3541 gcatcccacc agataactga ctaggatatt ggtctttaaa tgaaagcaaa ctagaatttt
     3601 ctaatgcttt ttctgctttt tcttgtcgtt cttctttagg tacaccacgg acttctaacc
     3661 cgtattctgt attttccaag atcgttcgat gtggaaacag accgaagttt tggaaaacca
     3721 tattgatttt atgacgacgg acttctcgca attcttcttt gcttaacttc gatacatctt
     3781 ctccatcaat atagatactg cccgaagttg gctcaatcag acgattcaat agacggatca
     3841 atgtggattt cccactcccg gaaagcccca tgatcacgaa gatttctcct tcttttacgt
     3901 caaaattcac gtcatacaca ccaaccgttg caccggtttt ctttaaaatc tccgttttcg
     3961 gctggtgatc attcatcata tctaaagcgg cttgtgtctt tttaccaaat atctttgtta
     4021 aatgttttac ttctactttt accaaacaaa ttctcctttt ttatgtaaat tcatttttct
     4081 ttctgaaaaa agtgaccaca ctatgttaac atcatgtagt cactttgtca aaaatgaaag
     4141 aaatttgctt gtccaaactg aaaaaaactt ggctaaatct ttgtaaataa aaggtttagc
     4201 caagttaata tttttttaat atttcacaca atcattctgc aagctgatgc tccgggtaaa
     4261 aaaagtttgt catacgctgt agtgtatatt catttccaat aaaatgaacg atgtcccctg
     4321 ccgtaaattt agcatagggg ccaggtgaaa caagcagttc ttcattatga gaaattgcga
     4381 taactgtggc gccagtcgcc tgccagatat tcaactcgct aattgaacgg tccagatgca
     4441 ttgctttttc tgataaagat aattcaaacg gaagtaaagg attcatctta tgtattcgct
     4501 tcgtttgatt gaccagctga tccaataatt gagaaaaatg attcagctca tcttgttgct
     4561 tctccacact tgccatgatt tctgcttttg tatcttggat ggattgtaca tcttgatatt
     4621 gcaataggaa atcttttgct ttttccttcg aagcaacaaa tgccccactt ccatgccgta
     4681 cttccatgat tccaagatct accagcacat tgatagcctt gcgggtagtc tcaggagaag
     4741 cattgtacgt actggcaagt gttgagcggg catggatctt ctcacccact ttatatcggt
     4801 tttcaacgat acgttcggct aaatcaacag caatctgctg gtagcgcggg cggacgattt
     4861 ttttctttcc agacattttc tttcctcttt ctttttttac tttccctcat cttactatgc
     4921 tctagcaaaa taagcaaaaa aggggagaat agcctcttgc aacgactgat catcgcttga
     4981 tctgttcctt ttttactggg caagctgttt gacagtcatc acaattctta ccggatttta
     5041 aacgagtata gacaattgcg cctgcacttc caaagattaa cacacttaat aagaatgtcg
     5101 ccatcctatt cctctccttc taatgacaat atagtataaa actggttctt ggattttggc
     5161 tgacggaaca aaacataaac gagtcctatc atcagtaaaa tagcaagata cgtccctaac
     5221 gctacctgtc caccctccaa taagtgtccc aactgataaa tcacaaaact aactaaataa
     5281 gctaaaccgc attgatagcc tatggcgatc caagtccatt tcttggcatt catttcccga
     5341 tggatagccc caattgccgc aaaacaaggc gcacaaagta aattgaaggc taacaatgaa
     5401 taagctgctg cgggagtata tgtgtgttgt agcacttgcc agatttctct gccattttcg
     5461 gatacttccg catgaccaaa caaaatacca aatgtgccaa taatattttc tttagcgacc
     5521 aatcctgtaa tcgctgcgac tgttccttgc cagtttcccc aaccaagcgg ctgaaaaaca
     5581 actgccagga ttcgcccgaa aaaggctaag atactttggt cttcagaaac aggttgagca
     5641 taaaaattat aagaagagct gaaccagatc acgatactag aaacaaagat aatcgttcct
     5701 gcttttttaa caaaagactt gctgcggtca taggtttgtc ttaggaccgc tgaccattga
     5761 ggaaaatgat atgcgggcaa ttccatgata aaaggagctg tatctccagc aaacaaacgt
     5821 gtttttttca agctgattcc agagaaaata attgcagtca taccaagaaa ataggcagaa
     5881 ggagctaccc aagattgatg aggaaaaaag gcccctgcta ctaaggcaat aatcggcaac
     5941 tttgcagaac aaggcatgaa ggttgtgacc atgatcgtca aacgacgatc ttgctcgttt
     6001 tcaatcgtgc gactggccat gacgcctggc actccacatc ctgtagcaat cagcatagga
     6061 atgaaggatt ttcctgaaag accgaatttc ctgaaaagtc gatccatgac aaaagcgatc
     6121 ctcgccatat atccgcagtc ttccagaaag ctcaagcata aaaacaatat aatcaattgc
     6181 ggtagaaatc ctaacactgc tcccacgcct gcgatgatgc cgttcaagat cagctcctgc
     6241 atccatcccg ctacttgcca ttcagctaac aatctgccaa catgttctgg taaccatgta
     6301 ccaaacaatg tgtcattgat ccaatctgtc cccattgttc ctactgtttg aatagccaga
     6361 taatagatca gccacatcac aaatgcgaag atcggcaagg ctaaccaacg attcgttgca
     6421 atctgatcga ttttgtcact catcgataat tggaaagaat catttgacac aacacagagt
     6481 gtacatagtt gggtaataaa ttcataacgt tcattgacca gaatcgtctc actatcgtcg
     6541 tccaatagtt tctctgttaa ctggatcagt tgctcgatct ctttttgctg agaaactgct
     6601 atctcgtaat cctctcttac cttctgatct cgttcaaaat atttcattgc ataccagcgt
     6661 ttcttgccgc tttgttctcc tagtacatct tcaatttcat gtaaagctgc ttctaaacgt
     6721 ggatcatatg tacagggaac aggaatagaa ggccgctttt ttgcagactc ctgaatcttt
     6781 tcgattagtt tttcgattcc ttgctttttc aatacgctga ttggtaaaac tggtacacca
     6841 agaccatagg aaagcttttc tagattgatt ttttttcctt cttttttgat gacatccatc
     6901 atattcagac caatgatcat aggaatgtct aaatccaata actgcgtagt taaataaaga
     6961 tttcgttcta aattggtagc atcaataatg ttgatgatca gttcaggctg ttcctgaacc
     7021 aaataatctc ttgcaatcac ttcttctggt gtataaggag acaaagaata gatgccgggt
     7081 aggtcctgaa tatgaatgtt cggatttttt ttcaacgatc cttctttttt ttctactgtt
     7141 acgcccggcc aattccctac atattgattc gaaccagtca agagattgaa caagctagtt
     7201 ttcccgctgt ttggatttcc gactaacgcg atattcattc tttttcctcc ctttgtatca
     7261 agattagttc ggcctctgac tttcgtaacg tcagttcata ccctcgcact gtcagttcga
     7321 ttggatctcc cagaggggct agttttcgga taactatttt tacatttcgc gtcaatccca
     7381 tatccattaa ccgtcgcttc actgcgcctt gtccgtggat tgctacgacg atcccagtct
     7441 ctcctgcttt taattgatca agagaagtcc agctttcaga ggaagcagtc tttttattga
     7501 caaagatttg acctagtatt tcccgactta ctgccactcg atgacttttt accagtaaaa
     7561 tggcattgtt gcctgataaa ttgacgacga cgattttact tccggcaacg atcccgatat
     7621 tttgcaaatg gcgttttgtt ttttcttctg tttcgattcg ttcgacttga taaacgaaat
     7681 tctgctttgc ctgcgctaag gtctgcatat tgattcctct cttgtgaaat aaatcatgta
     7741 ttaaaatcat tcattatatg ttctaatttt cttacgtgtt acgcaaataa atgagaatca
     7801 ttctcacata gaatactctc ggtaattgag aatgtcaatt atacttgtga tattatgagc
     7861 gaatctttag tattgataga taaaaatgag aaaaaaatat ttcttcatag ttttccacaa
     7921 ttttttctct attaaatttg ctattttccc acacgatact tgttttcagc tcttttttca
     7981 aaaacacaaa acttagtatt ccacagtttc cacaacacaa tatgtagtgt ttgttgtttg
     8041 acttttttac taagagtttt atactatcta ttatagataa taagaatgtg ttagaggagg
     8101 cactcaccat gaacgtaaaa atcttttcta aaaataattg tatgcaatgt aagatggtca
     8161 aacggttttt aacagaaaat caaattgctt ttgaagaagt caatatcgat gaacagcctg
     8221 aagcagtaga ctggttgaaa gcacaaggat tccaaagtgt tcctgtcatt acttctgatg
     8281 cagaaacagt tatcggattc cgtcctgatc agttgcgtaa acttgccagc taacatgact
     8341 aaaagaatca aaacgtgata catggatttg aagggcttga gacagcacca gtttttgtcg
     8401 caaacttcca aatccttttt taaagcttaa aaacaatgca atgatttgca atcaagcatc
     8461 atcaaatacg aaatgaaggt tgggcgtacg tatgagtctt aaaaatttac aagatgtcag
     8521 ttatttcaag ctgaataatg aaatcaatcg gccagtcaat ggtcaaatcc ctttgaataa
     8581 ggataaagaa gctttagttg ccttttttga ggaaaatgtc aaaccaaata cgatgacttt
     8641 tccatctatt atggaaaaaa tcaattactt gatcgatcaa gaatatatag aagcagaatt
     8701 cattcaattg tattcaccat catttattga aaagctatat caatttttgg acgagcaaca
     8761 tttttctttc aaatctttta tggctgctta caaattttat tctcaatatg cgttgaaaac
     8821 caacgacggt tccgcttatc tggaaactta tgaagatcga gtagccttca atgcgcttta
     8881 ctttgcgaac ggggatgaag aattagcact tgctcttgca gacgaaatga tccatcaacg
     8941 atatcagcca gctacacctt ctttcttgaa tgctggacgt aaacgtcggg gcgaattggt
     9001 gtcttgtttc ttgactcaag tcactgacga tatgaactct atcgggcgct caatcaactc
     9061 tgctttgcaa ttgtcccgta ttggtggcgg cgtagggatt actttatcaa atcttcgtga
     9121 agccggcgct cctatcaaag gatatgaggg tgctgcaagt ggtgtcgttc cagtcatgaa
     9181 attattcgaa gatagtttca gctattctaa tcaattaggt cagcgtcaag gagctggcgt
     9241 ggtttatttg aacgttttcc atccagacat tattgctttc ctttcagcaa aaaaagaaaa
     9301 tgcagatgaa aagattcgcg taaaaactct ttctcttggc gtgatcgtac ctgataaatt
     9361 ttatgaattg acacgtaaaa acgaagatat gtatttattt agtccatata gtgtcgaaaa
     9421 agaatatggt gtcccattct cttatgtaaa tattacagct gagtatgatc atctagttgc
     9481 aaatccaaac attcgcaaac aaaaaatcaa agcgcgtgat cttgaaaatg aaatctcaaa
     9541 attacaacaa gaatctggct atccttacgt aatcaatatt gatacagcga accgcgagaa
     9601 tccaatcgat ggcaagatca tcatgagtaa tttatgttca gagattttac aagttcaaac
     9661 gccttctgtg attaacggca aacaggaata tgaagtatta ggaacagata tctcatgtaa
     9721 cttaggctcg acaaatatcg tgaatttgat gcaaagccct aactttggtc aatctgtgcg
     9781 tacgatgact cgtgcattga catttattac agatgcatct gatatcgatg tcgtaccacc
     9841 gatccaaaac ggaaataagc tgaatcatac gattggatta ggtgccatgg gcttacacac
     9901 ttatcttgca aaagaacaaa tggaatatgg ctcagaggat tcattagact ttacaaatat
     9961 ttacttcatg ctgttgaatt attggacact tgttgaaagc aacaatatcg ctcgtgaaag
    10021 aaaacaagtt ttccataatt ttgaaaaatc agcttatgct gacggcactt atttcgaaaa
    10081 atacgtaact ggagaattcc agccaaaatc agaaaaagtc aaagcattgt ttgaaggcat
    10141 ttttatccca actgctgaag attggaatgc tttgaaacaa gcagtaatga aagatggact
    10201 gtatcatcaa aatcgcttgg cagtagcacc aaatggctca atttcatata tcaacgatac
    10261 gagtgcaagt attcatccta tcactcgcat gatcgaagaa cgccaagaga agaaaatcgg
    10321 taaaatttat tacccagcgc cttatctatc caatgagacg attccgtatt acacttctgc
    10381 ttatgatatg gacatgcgta aagtaatcga tgtttatgca acggcacaac aacacgtcga
    10441 tcaaggcatg agtttgactt tattcatgcg ttctgaaatc ccagaaggca tttatgaatg
    10501 gaagacaaca acgaagcaaa cgacacgtga tttgaatatt ttaagacatt acgctttcca
    10561 caaaggaatc aaatccattt attacgtacg tacctttact gatgatgcag aagaaatcgg
    10621 aagcaatcaa tgtgaaagct gcgtgatcta atatcataga tagattcgct tattcatatt
    10681 ttaattaaag gagcattctc atgtcagaaa catattatga agcaataaac tggaatgaaa
    10741 ttgaagatat cattgataaa tccacttggg agaagctgac agagcaattt tggctagata
    10801 cacgtatccc actttcaaat gacctagatg attggcgtac attgtctcaa ttggaaaaag
    10861 atacagtagg acatgtattt ggcggtttga cactgctaga tactgtccaa tctgaaagtg
    10921 gcatggatca gttgcgtaaa gatgtccgca ctccccatga agaagccgtt ttgaacaata
    10981 ttcaattcat ggaatccgtt catgccaaaa gttattcttc tatttttagt acactgaata
    11041 cgaaaaaaga aatcgaagaa atttttgact ggacaaatac gaatccttat ctgcaaaaaa
    11101 aagctgagcg tatcaatgaa atctacaaac acggtacacc gctagaaaag aaaattgcca
    11161 gcgtcttttt agaaacattc ttgttctatt caggttttta tactcctctt tattatttag
    11221 gaaacaacaa attggctaac gtagcagaga tcatcaaact aatcatccga gatgaatctg
    11281 tacatggaac ctacatcggt tacaaattcc aattaggatt caacgagtta cctgaagcag
    11341 aacaagaaac gttaaaagac tggatgtaca atcttcttta tgagctttac gaaaacgaag
    11401 aacgttatac agaagaatta tacgatccaa tcggctggac agaagaagtc aagacattcc
    11461 tacgctataa tgccaacaaa gcattgatga acctagggat ggatccactc tttccagata
    11521 ctgccaatga tgtcaaccca atcgtaatga acgggatttc aacaggcaca agcaaccatg
    11581 acttcttctc acaagtcgga aacggctatt tgttaggtca tgtagaagcg atgaaagacg
    11641 acgattattt gattggattg gaataaggat ttattttaat tcaaaaattt ttcgaaaaat
    11701 aaaaagagtt tagcgtacag atattttaaa tgtacactga actctttttt atgcttattc
    11761 acttgtttct tccagcactt ttggactgtc taacttttcc gaaacatgtt ccattcttct
    11821 caataaatag attttccgga tatttaatat tatcgtctta atcactgcat agacaggtat
    11881 gcaaatcagc atgcctaata ttcctgcgac acttcctgct ccaatcaata ccaagatgat
    11941 cgtcaaagga tggatattca ttgatttccc aaataacaac ggcttgatca aatttccatc
    12001 taattgttgg atcactaaaa tcgacaacgc catatacaaa gcttgaaatg gagagataaa
    12061 caaaccgaca atgattgctg gtaccgctcc aataaaaggg ccgacatacg ggataatatt
    12121 cgtgattccg caaatgaccg caagcaacaa gctataaggc tgatcgaata ttctcattgc
    12181 caaaaagctc attacaccaa taatcaaagc atctaagatc gtactgctga tataggcaga
    12241 taatgtttcg tttaattctt ttaccgtttg gcgtaactct ttacgaatcg ctttcggaaa
    12301 gaagtgagac aacgcatcaa taaatttgtg cccatccttg aacataaata gcaaaataaa
    12361 tggaacggta aataacaaaa taaaaaattg catcataaat gaaatgattt ttgagacact
    12421 tgcagataaa ctgactaata tgatattgaa caaattacta agagataaat ttgctgatgc
    12481 taattgttct tccaaattga aatttttaaa ctcttcccgc tgcgccaatt catttaacca
    12541 tttgcttgtt tcatctgcat acattggcaa gctctgggtc aattgaattg tctgttccat
    12601 taactgaggc actacattca tgacagttaa aacaactaaa atgattacga ccaaaaacgt
    12661 caataaaaaa ccgaacactc tcgggatccg atgcttttcg agaaaaacaa cgattggatc
    12721 gaacatataa tagataaaac cagcaacaag caatggtaaa aaaattgccg aaagcatttt
    12781 caatattgga ctaaaaatat tcggcatttg taaaataaag tacacgccga tgatcgtgag
    12841 tactagctcc actgtccaga aaaataattt tgattgttta aaacgtgatt gcatacatct
    12901 cctccaaggt cctttgatac ttctattcta tcatttaaca aagagttacg cgctgagatt
    12961 ttcatttgct taaaaaaaac aaaaaaaata aacatatttt aatgagtaga cgagtactta
    13021 aacaaaaaca cggtttggag tagtgacaaa aattatactg cagtcccttt ttccaaataa
    13081 acggtgttca aaagcttgca tcttcgtaat aagcccagcc aaacgaaaaa tataaggaac
    13141 tatttttatt tggctgggct tattacttga tgtaggacat ctattttaca acctcagatc
    13201 atttattgcg caatactgac taaatgcaac tttgtgatat ttttgtgtac ggacaactcc
    13261 tcgatcacat cggcataagt gagccctttt ggaagatcaa tcgtatagat atttttgtac
    13321 actcggtagt catcaacgaa ttttacgtca aaattcacat cttcgattac gatatttttc
    13381 tcttcaaaat aatcggtaag aaaatctttg gtttcttttc tatggataaa ttggatttct
    13441 aactttttag tcgtaggtac atggatcacg cgtttcacta ctgtgagtgc aatagcaatc
    13501 ccgataaaac tgatgatcgc aatggaatag taacccatgc cgatggcgat ccctaatcca
    13561 gcaattgccc ataaagaagc ggcagtcgta agtcccgtca ccgattgttt cgtgacgatg
    13621 atcgttcccg cgcctaagaa accgacacca ctcaccactt gagcaatcag ccttgcttca
    13681 tctgaacgaa tcgttccagc aagctgtgga tactctaaag catctcttaa tgcaccacta
    13741 gcgatctcaa cttggatcaa tgcaatgata catgctccca tacaaactaa aatatgcgta
    13801 cgcatacctg ctggacgatt tttatattgt cgttcaaaac cgattgctcc gccaaatagc
    13861 atagcgatcc ctaaacgtaa aataatctct ggaattgtca ataccatatc attcatctaa
    13921 acaccctcca gtccaatata tcatgtctga aaggagcaga caaaaaaagt gcaattttta
    13981 cctcttacga aaaaaggact gtgacaaaat ttttgtcata gtccttttta tgaataaacg
    14041 gtgttcaatc agctgaccct cggtattact caacaaacgg caaaatatgg ggagctattt
    14101 ttcctttgtc ttctctaata ctcaggtcaa aacgctgatt tcacaacctc tttagcctac
    14161 tattgaaaat tacaacttac ttgctgcttc ttcatcgatg atcacaacaa cattgtcgtg
    14221 attttgcaat acacttgctg gcaaatgatt cgttacaggt ccttcaatca tccctttgat
    14281 tgcatcagct ttgctttcgc caaatgccat caagacgatt tctttacttt tcataattga
    14341 accgattccc attgaaacag cttttgttgg tacatcttct gctttatcga agaatcgttt
    14401 gtttgcattg attgttgatt ctgttaagtc aactactgaa gtcgttccgt caaatgaagc
    14461 accaggttca ttgaaaccga tatgtccatt ttgcccgatt cctaagattt ggatatcgat
    14521 tggatgtgca tcgatgattt gatcatactt tttgcatgct gcttccagat cttctgcttt
    14581 tccatctggt acaaacgttt ctttgaatgg ttttttatca aataattgga catccatgaa
    14641 atgacggtag ctttgttcat ctgaaccgcc tagtccaacg tactcatcta agtttacaga
    14701 agtcatttca ctgaaatcca aatcgcttga agtcatttct ttatataaag taactggtgt
    14761 gcttcctgtt gccaatccta atacttttgc acctttgttc ataccttctt tgatgatttc
    14821 aaatgctttt tttccgcctt cttcagcgtt ttttacacga atgatttcca tagtgattgc
    14881 tcctttatat tttggtatag cccaattata gcattctttt tttcttttta caataattag
    14941 tatagaccaa attgcatttt tttcattttc ttgacaataa ataggaatcc gtgttaggtt
    15001 tcataagatg gttcaatcaa acaatccatg ttgcatgaaa accaagcaag tgattcactg
    15061 tggacgcttt atgtctgcag tttttttatg aaaaaggagt tattatgagt atactgacat
    15121 taaacaacat tacccagcaa tttggcgaca aaatcctcta tgaaggtgtc gatctgcaat
    15181 taaatgctgg cgaacatctt gggctgattg gacaaaacgg agccggtaaa agtacattga
    15241 ttaaaatcat cactggtgag atcttaccag atgacggaca gatccattgg caaaaaaata
    15301 ttcacaaagg ttacctcgat caatatgtgg aagtcgatga aacattaaca atcgaagaat
    15361 ttctaaaaac tgcgtacgca aaagaatacg aaaaggaaga aaaaattgct tttctttacc
    15421 aaacatatag cgagaccttc gatgattcct tgctggaaaa agctgggaaa ctccaaacgg
    15481 aattagacca aggagtgttt tatcaaatcg acaccttagt tgctgagatg agcagcgggt
    15541 tggggatcga tgtcttaggt ttagattcac tgttgaaaaa tctaagtggt ggacaacgtt
    15601 caaaggtgat tttagcaaaa ctacttttag aaaacccaga tgttctgatc ttagatgaac
    15661 caaccaatca cttagatgat cagcatatcc aatggctgac gcagtttctt caggattttg
    15721 acggtgcgta tatcgtgatt tcccatgacc aagaatttct tgatcagatc accacccata
    15781 tcgcagacat cgagtttgga aagattacta agtatactgg ccatctaaaa caagcattga
    15841 aacaaaagga acaaaatcgc gaaagctatt tgcgccaata tcatgctcaa caaaaacaaa
    15901 tcgaaaagac cgaagcttat attcgaaaat acaaagccgg ttcccgatca acgatggcaa
    15961 aaagccgaca aaaacaatta gataaaatcg aacggctgac gcctccagct tcagcaagta
    16021 aagctgtctt tgattttcca ttctcgccta ttgtcacgac attagcagtg gaaacaactg
    16081 atttagtcat cggatatgat cgaccgctac ttgcacccat caatttgacc atccgctttg
    16141 gtgaaaatat tgccattcga ggcttcaacg ggattggaaa atctacttta ttaaaaacac
    16201 tgatcggtga gattgaaaaa ataagtggcg atttccactt cccagataac acaaaaatca
    16261 attacttttc acaagatctg tactgggaaa atccattaga aacaccacta caatatttaa
    16321 gcagtcaatt tccaaaagcg actatcaaag aattacgtcg ccaactagct aaagcagggt
    16381 tagttaatca attagcaagt gaacctctca ctacattaag tggtggggaa caaactaagg
    16441 tgaaacttgc acagttgaca atgaaccaag gtaatttact gattctcgat gaaccgacga
    16501 accatatcga tcaagaaacg aaagaaagct tacaagacgg gatacagaaa tttccaggaa
    16561 cagtaatcat cgtctctcat gaacaagaat tttatcaaga tcttgtgcaa cgagtcattg
    16621 agattgaacc aaaataaacg tttgattgaa tagttgaaaa aaaggagctg tgacaaaagt
    16681 tttgtcacaa ctccttcttc tgaataaatg gtggccaatt agctgacctt cggtattagc
    16741 tcaaaaaacg gcaaaatatg aggagctatt tttatttggc tattcttatt acttgatgca
    16801 gaacagcttt tcacaacctc ttttcgtcta ttttttattt tcgagatttc tctttccttt
    16861 aaaaacaact gtttgaaaga agaacgcaca tccttgaaaa acaagcccgc taaccgttac
    16921 acctaaccag ccatactgct gccacattgt cgtccctagc aatgaaccag ccgcacctcc
    16981 aataaagtac ataaacataa ataca
//
LOCUS       DAFENC010000054        16074 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.056, whole genome shotgun sequence.
ACCESSION   DAFENC010000054
VERSION     DAFENC010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16074
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.056"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            59..174
                     /gene="rrf"
                     /locus_tag="LP493_002363"
     rRNA            59..174
                     /gene="rrf"
                     /locus_tag="LP493_002363"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(227..697)
                     /locus_tag="LP493_002364"
     CDS             complement(227..697)
                     /locus_tag="LP493_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HBL2134481.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(856..1314)
                     /locus_tag="LP493_002365"
     CDS             complement(856..1314)
                     /locus_tag="LP493_002365"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HBL2134482.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1485..2629)
                     /locus_tag="LP493_002366"
                     /pseudo
     CDS             complement(1485..2629)
                     /locus_tag="LP493_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
     gene            complement(2642..3559)
                     /locus_tag="LP493_002367"
     CDS             complement(2642..3559)
                     /locus_tag="LP493_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HBL2134483.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3987..4550
                     /gene="efp"
                     /locus_tag="LP493_002368"
     CDS             3987..4550
                     /gene="efp"
                     /locus_tag="LP493_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HBL2134484.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            4651..4821
                     /locus_tag="LP493_002369"
     CDS             4651..4821
                     /locus_tag="LP493_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134485.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            5036..6295
                     /gene="lysA"
                     /locus_tag="LP493_002370"
     CDS             5036..6295
                     /gene="lysA"
                     /locus_tag="LP493_002370"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HBL2134486.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            6282..7082
                     /gene="dapF"
                     /locus_tag="LP493_002371"
     CDS             6282..7082
                     /gene="dapF"
                     /locus_tag="LP493_002371"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HBL2134487.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            7085..7966
                     /locus_tag="LP493_002372"
     CDS             7085..7966
                     /locus_tag="LP493_002372"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBL2134488.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            7963..8679
                     /locus_tag="LP493_002373"
     CDS             7963..8679
                     /locus_tag="LP493_002373"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBL2134489.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            8685..9380
                     /gene="dapD"
                     /locus_tag="LP493_002374"
     CDS             8685..9380
                     /gene="dapD"
                     /locus_tag="LP493_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HBL2134490.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            9396..10397
                     /locus_tag="LP493_002375"
     CDS             9396..10397
                     /locus_tag="LP493_002375"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBL2134491.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            10394..11755
                     /locus_tag="LP493_002376"
     CDS             10394..11755
                     /locus_tag="LP493_002376"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBL2134492.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            11715..12866
                     /locus_tag="LP493_002377"
     CDS             11715..12866
                     /locus_tag="LP493_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBL2134493.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            12841..14010
                     /locus_tag="LP493_002378"
     CDS             12841..14010
                     /locus_tag="LP493_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBL2134494.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            14185..15564
                     /locus_tag="LP493_002379"
     CDS             14185..15564
                     /locus_tag="LP493_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBL2134495.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            15845..16074
                     /locus_tag="LP493_002380"
                     /pseudo
     CDS             15845..16074
                     /locus_tag="LP493_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5255 a         2840 c         3428 g         4551 t
ORIGIN      
        1 tgacttcaaa tccagttttg agtgaacaaa atttactcaa taaaagataa caccacagtg
       61 tggtggcgat agcgagaagg atacacctgt aaccatgccg aacacagaag ttaagcttct
      121 tagcgccgat tgtagtgagg ggttgcccct tgtgagagta ggacgtcgcc acgcaaaggc
      181 aaaaagatga actagaaata gttcatcttt ttttattttt attaagttaa agaacggatt
      241 caattgcagc ggtcattttc aatggagaag tttgtggtgc aaatcgttcg attactttgc
      301 catttctatc aatcaaaaat ttagtaaaat tccattttat tgctttagtg acagtaccag
      361 gagcttcatt tttaagataa gtaaaaagag gatctgtatt ttctccattt acgtcaatca
      421 attgatgcat agggaaggta acgccataag tggttttaca agcttctgct gcttcagtcg
      481 ctgaatctag ctcttgttta aattgattgg aaggaaagcc taagataacc agaccttgtg
      541 tctgataagc ttggtaaagt tcttctaatt gtttaaattg aggtgctaga ccgcattttg
      601 ttgcagtgtt aacaatgatt atcggtttgc ctgcatattt tttcaatgaa tagacagtgc
      661 cgtcttctaa agtagtttca aaattataaa tagacataaa gttttctcct ttctatttta
      721 tataataaaa agagcgctaa actgaaaact agctatttgt tttcccgttt agaactcttt
      781 tcagacaata aatatttaat aaaatacgaa gataagatag ctatattgct tctcatcttt
      841 acgttctttt agaaactatg cttctacttc agaccattca tcgcgttttg ctaaaaattc
      901 acgagccaaa gcttgtgcac cttctagtgt atggctggca gcccagccac attgtgtttc
      961 attgcttgca ggtacttcag tagcttcaag aacatctttc attgttgctt caagaacatc
     1021 taaaatgtct tcgtagcttt catgattcaa tacagtcaag taaaagcctg tttggcatcc
     1081 cattggagac cagtctacga tgtaatctgc gtgattgcgg attagttcgg cagtcaagtg
     1141 ctcaagtgaa tgtagacttg gcatgtccat gtgttcttta tttggttgtt taaagcggac
     1201 gtcgtattta atgatgacat cgccatgcgc acccgttttt cgatcagcta cacgtacata
     1261 aggtgctttg acttttgtat ggtcaagatt aaaactttcg acattcattc tcatttgtaa
     1321 gactcctatc tgtttgttca ttcgttttga tgcttttcac taaagaatta tttagtgaaa
     1381 tttacaaaaa cgtctttcta cttgattcta acacttatcg tttccaaggt gtagcaatct
     1441 gaaatatttt ttagattttt ctgctaagtc gtttattggg acttctagtt cttgattctg
     1501 tcaaatgcct gagctaaatc gtttatgaga tcctgaccat actcaattcc tacagaaaga
     1561 cggatcaagc cgtcctttat gccagcctct tctcgttttt cttttggaat agacgcatga
     1621 gtcatgacag aaggaatttc cactaaactt tctacgccac ctaaactttc tgctaaagta
     1681 aatagttgga gtgattcaac aaatggaata gcagattctt cattttttaa agtaaaagaa
     1741 atcattccgc taaagccgct catctgctgc ttagcaactc catggagttc atgatcgggt
     1801 aatcctggat agtagacctt ttctactgct ggatgagaaa atagaaaatc agctaccaca
     1861 aaagcatttt tttgatgttc ctccatacga acacttagtg tcttgattcc gcgctgaagt
     1921 aaccagctat cttggggacc aagtacggct ccgatagcat tttggtaaaa tccgatctga
     1981 tcggctagat cttttggtta gaagtcacta aaccagctac tacatcgctg tgtccgccta
     2041 gatatttggt accgctatgg acaacgatat cagaaccgag atctaaaggt ctttgaaaat
     2101 aaggagtagc aaatgtattg tcagcaataa ctatcaatcc atgttgatga gccagagtgg
     2161 cacttttttc taaatcagta atctttagaa gcggattgct aggtgtttca agataaagtg
     2221 cttttgtatt gggtttgatg gattgttcta ttttatcaag attactcgta tctatgatcg
     2281 tgtactcgag accattttta gtaagaactt tgtcaaatag acggaatgtt cctccataga
     2341 catcatctcc taataagata tgatcgccag cttgaaaaag agaaaaaacg gcatgaatcc
     2401 cagaaagacc agaagaaaaa gcgaatcctc gaacaccgcc ttccaaatca gcaatcagtt
     2461 cttccaatgc aaaacgagta ggattaccag atcttgaata ttcatattgt ttaggctggc
     2521 cgacgccatc ttgccgataa gtggatgttt gataaatagg tacactgaca gctcctgttg
     2581 tgggatcttc actgatgcct ccgtggatca attttgtttg aatgtgcatg tttctttcct
     2641 cctataagta aatgtttttt gataaatagc ggtctgctgc gtctggaaaa atcgtaacga
     2701 cacgatgacc aggtggtaaa cgacgaattt ctcttaatgc tgctgcaaaa gccgcaccac
     2761 tcgaacttcc aactaatagt ccttgttctc gtgctaactg cctagtatag ttaaaccctt
     2821 ctacatcaga gattgtctcg atctgattga ttgaaagggg agaaagaaac ggcggaatga
     2881 attctacacc gataccctca atttcgtgag gggctggatc accaccattt aacacagagc
     2941 cctctggttc tacaccgatt attcgaatgt cgggatattt ttctttcaaa aaggtagaag
     3001 ttccagcaaa ggttccacca ctcccaattc ctgctacaaa actatggata ttttctttga
     3061 tttcatgaaa gatttctggc cctaacgtat gatagtaagc agcaggatta tctttatttt
     3121 caaattgaag aggcagatag ctgtttgata tctcctctgc aagtttttta cttttgctga
     3181 tggcaccgat gattccttgc tcactaggag aatggatgat ctttgctccc aatgctttca
     3241 tcaattgttg tttttctaag ctaaacttct ctggaacaac aaaaaccgtt cttaatttgt
     3301 atgtgagtgc ggccagagcg atcccaattc ctgtatttcc ggcagttggt tcgatgatcg
     3361 tcgttttttc attgattttt ccttgggcaa atccttcttt gatcaaataa ctgcccaatc
     3421 tatctttgat acttcctcca ggatttaaat attctagttt tgcataaata gcagaacctt
     3481 taggcataga atagtgctga ttgtcaaagc gataaagcgg tgtggaacca atagcttctg
     3541 taattgtcga gataatcatg tgggcctcct aaaaaaagat aataaaaaaa ggagctgact
     3601 attaaatcag ctccttgaaa gacatagaga aaaattgagt agataaaaag ataagttacc
     3661 tggtactcat tctatgaagg gcaattaata gacatgacaa atagtatgct gcttttatgc
     3721 accatacaac agcaacgatt caattgtttt tggttgctga ctgtcatgtg tatccctcca
     3781 agtaaaattt ttattaacga tagcatgaaa aaaaataaaa gtcaaaggct tgaaagaaaa
     3841 aaatatttcg atagcatcgt ttacccgtgt ttatttttct gacaaatagg catgagacct
     3901 taaaagatag agaatactct agttttctgg ccggttgtct gatacaataa agttgattat
     3961 gataaagaaa agaaggagca aaaataatga tctcagcaag tgatttaaga gccggtatga
     4021 ctttcgtaca agacggcaaa ctgattaaag ttctggatgc aagccaccat aaacctggta
     4081 aaggaaatac agttatgcgt atgaaactga aagatgtccg ttcaggtgca acatacgaca
     4141 caacgttcag accagaagaa aaatttgaaa aagcacatat cgacacaaaa cctgtacaat
     4201 atttgtacac gatggatgat acagctttct tcatggattt ggaaacatat gagcaatatg
     4261 aaattcctgt agaaacagta gaagaagaaa tgaaatatat cctagaaaac atggaagtaa
     4321 aaatccaatt tttcggtagc gaagtcatcg gcgttcaatt accaacaact gtcgtattac
     4381 gtgttgtgga aacacaacct tccatcaaag gtgcaacagt cactggttca ggtaagccag
     4441 cgacaatgga aactggctta gtagtcaatg ttcctgactt catcgaaaca gatgaattgt
     4501 tggaaatcaa tacagcagaa ggttcttatg taaaacgtgc gtcaaaataa ttcgctaacg
     4561 gattgataag aatttgaaaa cagagcttga cctcttgaaa ggcagatcat cggatctgcc
     4621 tttcaagagg ttttttgtgg aatcagcaaa ttgaaaaata aaaaagtatt tgattttatt
     4681 tatattttga aagatgaatg gcaaaagcta gagaaagaaa aaactgcact tatttatgaa
     4741 gaaattgaaa tgattcataa aattgaaaat atccgaacta ttccgaacta tattgaagcg
     4801 aaaatatttt ttcatcacta aatagtgttg aatttatgtt tttatgtata aatagcttct
     4861 aatagttcgg gtattttgtt tttataacca tttttattct tatttttaaa aaaatatttc
     4921 gaaatatact agacaattca gaaaattttg tttaatatta ttccaataaa attcaaatct
     4981 ttatcaaatg aaattccaat aaaaacggaa aaaaagtgaa aagaggaatg aaaaaatgac
     5041 agaattgata attggcggag tcacagcaag cacattggca gaaaagtata agacacctct
     5101 gtatgtgtat gatgaagaaa agatgagaca aacgatgctg tcattcaagc gaggctttgt
     5161 atcgaaacgt tttgatacaa aagtgcttta cgcctctaaa gcattccaaa cgattgagat
     5221 gctgcattta gttcgtgaat atggattcgg gctagatgtt gtcagtggtg gggaaatcta
     5281 taccgctttg caagctgatt ttcctagaga tactatctac ttccatggta acaacaagac
     5341 gccagaggaa ctgatctatg cacttgaaaa tgatttgttg catattgttg ccgataattt
     5401 gatggaagtt gaattattag cagaattaag ccaacgctat ttaaaaaaaa tctgtatcat
     5461 gcttcggttg aatgtcggag tagaagcaca tactcatgaa tatatcgtca ctgcgcatat
     5521 tgattcaaaa ttcggcatga gctatgaaag taaagagtgc caacaagccc ttcagttgat
     5581 aaaagaaagc agctatctag agttagaagg atttcatgct catatcgggt cacaaatttt
     5641 tgatgttact gcttggttag ctgaaatcga caaattgacg aattacttaa ccgattttga
     5701 ccaacctctt tccttgaatc ttggcggagg gtttgggatt cgttatacac aaaatgatca
     5761 gccgatccca gtcgaagagg cactaaaaaa actgattgaa tatacggaag aagctttgga
     5821 aaaacgaaaa ctgaccattc gtcaattact gatcgaaccg ggtagaagta ttgttggaga
     5881 agctggtaca acactataca cgattggttt catcaaaaag acaccacata aaaaatatta
     5941 ctttgtagat ggcgggatga cagataatat ccgtccagct ctgtatcagg cagaatacga
     6001 ttgtgattta gcagcaaaac tgtcggaaga aaaaacagag aaagtgacga ttgcaggaaa
     6061 aatgtgtgaa tcaggcgatg tggtaattaa agaagcttat ttgccgaaag cagaatcggg
     6121 tgatctttta gctgtttatt ccacgggagc ttatggatac tcgatgagca gcaactacaa
     6181 tcgagcgaca cgaccagcag ttgtttttgt caataatggc caatcaagac tgattgttcg
     6241 cagacaagca ttttctgatc tactaagggg ggaagtttcc tatgatcctt cataaatata
     6301 atggctgcgg aaatgatttt atcttattag attacgcaga agacacagat tatagtcaat
     6361 tagccgcttc tttatgcaca aaagaaaaat atgatataga cggattgatc gccgtaaaaa
     6421 tcgatccgtt ggaaatgatc tattacaaca aagatggcag ccgcgcgccg atgtgcggaa
     6481 atggcattcg ctgttttgct cgatacgtaa atgatcagaa catgatgaat gaacaggaat
     6541 tcaacgtaga gacattagca ggcacaagaa aaattacggt gttggatccc tcaccttttt
     6601 attgcagcgt agatatggga gtgccagatg attctccgga aaaaatcaaa gctaatcaaa
     6661 cttatccaat aaaaaaccag gaaatagaga tcaatggtga aaaagtaacg atcactagtt
     6721 tatttttagg aacgattcat accgttgttt ttgttgaaaa tgcgcgtgag gaagtctgga
     6781 gaaaaagagg tgaactgatc tgtcatcatc ctttgttcaa agaaaaaacc aatgtcaact
     6841 ttgtagaagt agtcaatgaa caagaattga tcgtccgtac ctatgaaaga ggagtaggtt
     6901 ggacacttgc ttgcggtaca ggttgctgtg cctcttatgt ggttgctaag gaaactggga
     6961 aaatttcagc agatcaggta gttgttcact tggaacaagg agacttgatg atctctggtg
     7021 aggatgcgat acaaatggct ggcccagcag ttcatgaatg gacaagaata ttggaggaat
     7081 gaagatgata aaaggttcga tcgtggcgct gatcacgccg atgaatgaag agggatcagt
     7141 agattatgct ggtttggaaa aattgatcca attccattta gatgaacaaa cagatggatt
     7201 attagtttta ggtacaacag gagaatcttc tacgctcaca caatctgagg aggagcagat
     7261 ccttcaactg acagtaaaga aagtggctgg ccgtgtgccg gtgattgcag gagctggaac
     7321 gaataatacg aaagaaacga ttgaaaaagc gaagcatttt gcttctttgg gggcagacgc
     7381 acttttggtc atcacccctt actacaacaa aacaagtgat gcaggactag ctgctcattt
     7441 tacagcaatt gcagaagcct caccgattcc gcttattttg tataatgttc cttctagaac
     7501 aggcatgtcg attccaatcc atgtattagt aaatttagca gaacatccta atatcattgg
     7561 tttgaaagaa gcctcaggag atatggctta tgtgatggat gccgctcggt tgattggaga
     7621 agaattcttc ctttacagtg gaaatgatga tttgatccta ccagtaatga gtgtaggagg
     7681 aagcggtgta ataagtgtat gggcgaatat ccaacctaaa atagtccatg aattagtaaa
     7741 agatacgcag gacggaagat ggcagcaagc aaaagaaaag caattaaatg cacttgaact
     7801 gatccatgcc ttgttcagtg agaccaatcc tattcctgtc aaagcagcca tgtcattatt
     7861 agacttacct tccggacctc tacgcctgcc tttagtttct ctttcaaaag agaaaaagaa
     7921 acaattagct cagcttttgt taaaagaaag gacggttgaa aaatgaaaat cggactgatt
     7981 ggcagtggac agatgggaaa tagagtcgaa gaagttgcac aagaaagagg agatacggtc
     8041 cttcttttac ggacggcacc taaagaagca actacgcttg cttttacgga actgccagaa
     8101 ctgcttattg atttttctca tccagataat ttagagaaaa tcctttcgta tagcttatca
     8161 tatcaacttc cgttagtcat tggcacgaca ggttatacac aatcacagtt ccaagaaata
     8221 aaagaacatg ccaaacatgt acctgtgatg tatagtgcta atttttcgtt cggcatcatg
     8281 gtgatgaatc aactaatcaa gcaagcagct gcaatgttgc aaggctggca gatcgaactg
     8341 attgaaaaac atcatagtcg taaaaaagat gcaccatctg gtactgcaaa tatgctgctt
     8401 caaacaatcc aagaagtgca aaagctgcag cccgtataca actggcaagg gaaaaaaaga
     8461 gaagaaaacc aaattggtgt acacagtatt cgtgcaggtt ctttacctgg tgaacatgat
     8521 gtattgtttg ctgctactga tgaaatattt acgatcaaac atgaatcttt ttctaatcga
     8581 atctttgctg caggcgcagt agaagcagcg gactggttga aagatcagtc accaggttat
     8641 tacaaattag aagatttatt aatggacaaa ggggtgtaaa aaacgtggaa gctcaagaaa
     8701 tcatccgcta cattcaaacg gcatctaaaa agacgcctgt gaaagtctat ctgaatgtaa
     8761 ccgagccaat cgaatttaaa gaaagtaaag tttttggtga aggaagcagc ttcgttgttt
     8821 ttggtgacta tgagacgatt gctccggttt tagaagctga atcagaaaaa atcattgaaa
     8881 tcgaaatcga aactgctgca agatacagcg cagttccttt gctagatatt aaaaaaatta
     8941 atgctcgtat cgaaccaggt gctattatca gagatcaagt gtcaatcggc aacaatgccg
     9001 tgatcatgat gggagcgatt atcaatattg gtgcagtaat cggtgaaaac acgatgattg
     9061 atatgggtgc tgtcttaggt ggacgagcga cagtgggcaa aaactgccat attggtgcag
     9121 gagctgtctt agcaggtgtg atcgaaccag catcggccaa accggttatc gtagaagacg
     9181 gcgtactggt aggtgcgaat gcagtgattg ttgaaggtgt ccatatcgga aaagatgcag
     9241 tcgtggcagc aggagcagtg gttttagaag atgtggcagc agaaactgtt gtcggtggaa
     9301 tacctgcacg tgtattaaaa ataagtgatg atcagacaaa agaaaataca gcattgattg
     9361 ctgcgttacg cgaattatag aggagatgga gaaaaatgcg cgaaatagat acctgtattg
     9421 tgggggcaac cggattagtc ggccaaacga tgctcaaagt gttagaagaa tatgattttc
     9481 cagtaggacg attgaaatta ttagcttcaa aacgttcagc cggtaaagtt tgtgtattca
     9541 agaaaaagaa acacactgta caggaattga cagaaacttc atttgaagga tatgatttag
     9601 cgctattttc tgcaggtgct tctgtatcca aagagtttgc gccaatcgca cgaagtcagg
     9661 gactatttgt catagataat tcctcagcat ggcgggaaga ttcggatatt ccattaatcg
     9721 ttccagaggt caatctggaa gactatacat tgaatcggct gattgcaaat ccaaattgtt
     9781 caaccattca agcggtactt ccgcttaaag ctttacaaga agcctttggt atccagcgag
     9841 tcaattattc gacctatcaa gcagtttctg gttccgggca aaaaggcatt gaagatcttc
     9901 atcgtacgca aaatgacgag gaaccagttt tgtatcctta taatattagc caaacggtga
     9961 ttccggaaat cgatcagcct ttggaaaatg ggtatacaaa agaagaacag aaaatgataa
    10021 atgagacccg taagattctg catcagcctg ctttgccagt atcagcaacc tgcgtacgtg
    10081 tgccaatcga aaatggacat ggagtctctg tggcagttca actgcaaaaa gagtttacga
    10141 cggaagaaat tagagagtgt ctcagccagt ttccagggat tcaattagaa gatgatctag
    10201 cagcacataa atatccgacg agcattcttg ctagaggaac agatatggtt tatgttggga
    10261 ggatcagaaa agacacttct ttagagaacg gattgttgtt ctatacgact gccgataaca
    10321 tacgcaaagg agccgctgcg aatgccgtac agattgctgc agctttaatg cagaaaatag
    10381 cggaggtggc aagatgagta atacgctgaa agtagcgaaa ttcggcggaa catcgatgtc
    10441 tcatgaagag caattcaaaa aagtccgtac aattgttctt tcagatccca atcgccaagt
    10501 gatcgttgtt tctgctttag gcaaacgtac gtcagatgat gacaaagtaa cagacttact
    10561 ttatttgatt tatgcttacc ttcagcatca tgttgattgg acaccccttt ggaaaaggat
    10621 ttgtgatcgt ttcattcaag taagagatgt tcttgccctg cagttaccta ttgaagatga
    10681 actagcacgc atacagaaac aactggaaga cgaaaagata actgaagatt atttagtaag
    10741 tagaggtgaa tatctgactg ctcaactgat ggctgagtat cttggttacc agtttattga
    10801 cgcaaaagac ctgattttct ttgactatga tgggaaaatc gatcaggaaa aaacagcaca
    10861 ggaaatcaca aaagcattta aaagatatcc gaaaatggtt gttccagggt tttacggggc
    10921 gaaccctgca ggaaaagaaa aattattggg ccgtggggga agcgacatta ccggcgcgat
    10981 actggcgaag atgttgcaag cggaaagtta tgagaattgg acggatgttt caggaatcat
    11041 gatggctgat ccgcgaatca tcgatcatcc taaaatcatc gaggaaatct cttttagaga
    11101 actgagagag atggcttata tgggggctaa cgttcttcat gaagcagctg ttttcccagt
    11161 tcaagaggct gatatcccca tccaaataaa aaataccaat gatcctttcg ctcaagggac
    11221 aaaaatatcg aatcacgaaa tagaaaagga aaatggactg acaggaatag ctggacgcaa
    11281 ggattttctt tccatcactt tattcaaacg tcatatgtcc gatgaaatcg ggtttatctg
    11341 gaaagcaatg agcatttttg ctaaacatga gatatcaatc gaacatattc cttcagggat
    11401 cgacaatatc ggagtgatcg tctcagcaga agcgattgcc gataagttat ttctcatcac
    11461 gaaagaatta aaagaaacac ttggcgtgga agaaatcgtc gtgatcgaag acttagcttt
    11521 gatctctgtc gttgggggtc cgcataaaga attgattgga ttatctggga aagtgttatc
    11581 gatattgaac aaattagaaa ttcgcacatc gatcttatca caaggagcac aggagttgaa
    11641 tctgatcatc ggtgtaccga ataatcaata tgaaacagta gtgaagggta tctatgaagg
    11701 gatggtgaat acggatgctg aaagaatatc gaatggcact ccatcaaatt cctgaaatcg
    11761 ggtttcatga attcaagaca aaaaaatatt tatatgaaca agtaaaaaac agcgaggccg
    11821 ttatccatga aatcggcgaa acaggactac tcctttattt tgataatcag caagaagaaa
    11881 cgattgcttt tcgaacagat atcgatgcac tgccagtcaa agaagaaacg aatctctctt
    11941 ttgcttctaa gcatgaaggt tatatgcatg catgtggtca tgacggacat atggcgatgc
    12001 ttttagggtt gactgacttt ataactaaac acattgagga tcttatttat aatgtagtac
    12061 tgatctatca gccatcagaa gaaatttccg gtggcgcaca aagcgttatt cagtcaggat
    12121 tgttggataa atatgaagta caagcaatat ttggctttca tctatggcct ggactagcta
    12181 agggagaagt tttctctcga ccaggacctt tgatggcaca aagcagtgaa acagacatta
    12241 tcattaaagg ccagtctgca catattgctt ctagtgaaaa aggaatcgat agtctggagg
    12301 cagctgtacg atttttgaag aatgtttatg attttgaccg gcaattaccg gcagagtgga
    12361 atcatctaat gaaatttggc caaatccaag gtggaacgat ccgaaatgtt ttagctggag
    12421 aagttattgt atccggaagt atccgttctt acagttcaga tatgcaaaat tatttgaaga
    12481 ggggattaga ccatttagca gaacagtttc actctacagc tactatttct tttcgctata
    12541 atgacggcta tccagctgta atcaaccata gaggcttata tgcagcactg ttagattcaa
    12601 acaaactaca tgaattagat gctccagttc ttcaagccga agattttggc atatatacgc
    12661 aacaatatcc atgtgtattt ttctttttag gtgtcggtga tacccctgct ttacatgatc
    12721 cgacgttcga ttttgatatg gatgttttag aaaatggtgt agaatggtac aaaacgattc
    12781 tttttacaga aaatcttctt gtaaaaatcg atagcagttc aaaagaggag cgagtaaata
    12841 atgatgaatt tatccaatcg atttagtcct aggctttcta gaatagaagt atcaaaaata
    12901 cgacaattcg atcagcaaat atcgtcgata ccagatgtga tcaaactcac cctgggagaa
    12961 ccggattttc caactcctga acatgtcaag caagcaggaa tagcagcgat tgaagaagac
    13021 ttttctcact ataccggaat gagaggatta gaggaactgc gggaagcggc ttgtatattt
    13081 cagcaacagc gttatggatt aacttatgat ccgcaaacgg aagttttgac gacagttggt
    13141 gcaacggaag cgattgcctc tgcgttgtta tctgttttgg aagaaggaga caaggttctt
    13201 attccagcgc ctgcttattc aggatatcag ccattagtgg aactagctgg tgctgaattg
    13261 atcccgatag atacttctga cacagggttt gtctgtcagc cggaacaatt tgaacgagca
    13321 tttgaacaat atggatcagc tgtcaaagca gtcattttaa actatcctaa caatcctact
    13381 gggacgacat tgtctgcaaa acaattgaaa gcaatcgctg aggttttaaa aaaatatccg
    13441 gtatttgtta taagtgatga agtatatgct gaattgactt atagtggaac gcatatgtcc
    13501 atagctactt atcttccaga acaaacaatc gtgataagcg ggttatccaa gtcacatgcg
    13561 atgactggtt ggcgagtggg ctttattttt gctcaaaaag cccttattga cgaactaatt
    13621 aaagtccatc aatatctggt gactgccgct acaacgatgt cgcaaaaagc tgcggctgaa
    13681 gcgctaataa atggggtgaa agatagcgag aatatgaaag agcaatatca aacacgaaga
    13741 gactatctgg tccagcaatt ggcgccttta ggatttgaag tgacccagcc aaacggtgca
    13801 ttttacttgt tttgcaaact cccagctgcc attcaaactg actcttggca gttttgtgta
    13861 gaattagcgg aacaggcaaa agttgcgtgt atcccaggaa ttgcatttgg cccagaagga
    13921 gaaggttata tccggatttc ttatgctagc agcatggaaa aattacatga ggcctgcaaa
    13981 cggatcaaag actttttaac agaacagtga ttcatagatt ttatcaaaaa aacaatcgtt
    14041 aattttgcgg tatattctgc aaggagacga ttgtttttta aatttagttc aaatgaacgc
    14101 gtttcttttg attcataact aatgtaatgt taagtttaaa ttgtttagaa tgattttaaa
    14161 agaatattca aggaggtttc atcaatggaa aaaatcaaag ttgtcattgt aggtgcatct
    14221 catggagggc atcaatcgat cttggaacta ttgacacgat acggtgaaaa tgtagatatc
    14281 acgctatttg aagcaggaga ctatatttcc ttcatgtcat gtggtatgga gctgtattta
    14341 gaagacaagg taacagatgt aaatgatgta cgtaatttca gaccagaaaa ctttccgcaa
    14401 tccaatgttc atattttaaa taatcacgaa gtaaaaacga tcgatgccga taaaaaaaca
    14461 gtaacggtta ctagcgcatc agataacgaa acaaaagaat atccttatga caaattgatt
    14521 ttgagttctg gtgtcaaacc aaacaatctg ccagtaccag gagcagatct agaaaatgtc
    14581 tacttgatgc gtggatacaa ttgggcaacc aaaatcaaag aaaaattaaa tgatccggct
    14641 attaaaaaaa tcgctgtcgt aggtgcgggt tacattggga tcgaagcagc agaagcaagc
    14701 cgaaaagctg ggaaagaagt cgtattgctt gatgtgatcg atagaccttt aggcacttat
    14761 ttagatgctg agatgacaga tattttagaa caacacctaa atgaaaacgg tattgaagtt
    14821 ttgacaaatg caaaaatcga agcttttact ggtaacggaa aagttgaggc aatcaaaaca
    14881 agtgaaaaag aaatcccagc agatctagtc attcaagctg ccggtgtgaa ggcaaataca
    14941 gaatggttaa aagggatcgt cgacttagat gaacgtggct ggatccaaac aaatgaatac
    15001 ttgcaaacga atcttccaga tgtgtatgca gtaggagatg ctacacttgc ttattctatc
    15061 ccagcacgca aaaaaatgcc gatcgcttta gcgactgttg cacgtagaga agcacgttat
    15121 gtagtaaaac atctttttga agaagtacca aacaaaccgt tcggcggagt cgtaggttcc
    15181 tctgcattaa gtgtctttga ctatcatttt gcagcaagcg gattgaatag ctttacagca
    15241 gcaaaagcag gagtagatgt acgagtgtct tattatgaag atacgttacg accaaaatat
    15301 gtaccagaag aacaaggaaa tccaaaagtg tccatccaat tattctcgga tccaatgacc
    15361 catcaattgc taggaggagc agtattatct acctatgatg ttacaggtca aggaaatgta
    15421 ttggcactag cgatccaaaa caaactgact ttagaagaac tagcagaagc tgacttcttc
    15481 ttccagccag gctttgaccg acaatggagc atgttgaatc tagccgctca acaagcgtta
    15541 ggagaagaac catttgtaga ataagaaaac gaaatatttg aaaagaggtt gtgaaaaagc
    15601 tgccttgcat caagtaataa gaacagccaa gtaaaaacag cttcttatgt ttttaacttg
    15661 gctggactta ttaccgcaga tgcaagcttt tgaacaccgt ttattttcaa aaaagggact
    15721 gtgacacgat ttgtgtaccg acccccaaaa gttagaccaa aaaatctaac ttttggaggt
    15781 cggtattttt tatggttaaa tatacttttg aacttaaatt aaagatcgtt catgattatt
    15841 tggatggcaa aggcgattgg accgtaaaaa tccagatcaa gagattgaag cggaaatgct
    15901 taaaattcgg gagaagcaca aggattatgg ctgtttacgg atgaccaatg aactaagaaa
    15961 ccgcggtttc tctatcaata aaaagaaagt tcagcgcttg atcaagaagc taggaataaa
    16021 agtaacggca tacacgcgta aatcacgtcg ctacaattct tatcgaggaa aagt
//
LOCUS       DAFENC010000055        14793 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.057, whole genome shotgun sequence.
ACCESSION   DAFENC010000055
VERSION     DAFENC010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14793
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.057"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            141..398
                     /locus_tag="LP493_002381"
     CDS             141..398
                     /locus_tag="LP493_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134496.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(630..1061)
                     /locus_tag="LP493_002382"
     CDS             complement(630..1061)
                     /locus_tag="LP493_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HBL2134497.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEK
                     LLYITKTSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
     gene            complement(1412..2104)
                     /locus_tag="LP493_002383"
     CDS             complement(1412..2104)
                     /locus_tag="LP493_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBL2134498.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            complement(2541..3110)
                     /locus_tag="LP493_002384"
     CDS             complement(2541..3110)
                     /locus_tag="LP493_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBL2134499.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(3184..3507)
                     /locus_tag="LP493_002385"
     CDS             complement(3184..3507)
                     /locus_tag="LP493_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134500.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(3661..4473)
                     /locus_tag="LP493_002386"
     CDS             complement(3661..4473)
                     /locus_tag="LP493_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134501.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            4827..5675
                     /locus_tag="LP493_002387"
     CDS             4827..5675
                     /locus_tag="LP493_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HBL2134502.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            5820..6761
                     /locus_tag="LP493_002388"
     CDS             5820..6761
                     /locus_tag="LP493_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HBL2134503.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            6751..8922
                     /locus_tag="LP493_002389"
                     /pseudo
     CDS             6751..8922
                     /locus_tag="LP493_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(9034..11205)
                     /gene="copB"
                     /locus_tag="LP493_002390"
     CDS             complement(9034..11205)
                     /gene="copB"
                     /locus_tag="LP493_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HBL2134504.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIR"
     gene            complement(11225..13411)
                     /locus_tag="LP493_002391"
     CDS             complement(11225..13411)
                     /locus_tag="LP493_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HBL2134505.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGLIAVADQIKLEVKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLCLNRHMKK"
     gene            complement(13411..13620)
                     /gene="copZ"
                     /locus_tag="LP493_002392"
     CDS             complement(13411..13620)
                     /gene="copZ"
                     /locus_tag="LP493_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HBL2134506.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(13633..14073)
                     /locus_tag="LP493_002393"
     CDS             complement(13633..14073)
                     /locus_tag="LP493_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HBL2134507.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYYPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(14147..14686)
                     /locus_tag="LP493_002394"
     CDS             complement(14147..14686)
                     /locus_tag="LP493_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL2134508.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQLFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
BASE COUNT         4282 a         2991 c         2564 g         4956 t
ORIGIN      
        1 ttctgtccac gttcatttta ctccaaagtt ttcctcattt caaaagaaaa tcacagaata
       61 cacgaagaag cgtttctatt tgtataaact atatcaaagt tctatactta aattatcaaa
      121 taaaaaggac gtgaagataa atgtcaaatt tagaaaacaa agaagaaaaa gttgtaaaca
      181 aaattgtttc tgttgtcaat aaactggata aagagttaga cgaacttgat acgttatctg
      241 aaaatccaga aaaaaaacat aacctaaaaa aatggttagt tgaacgaaag gctattcatg
      301 aaattaaaaa agttcttcat gaagctgata aatatgaaaa atatgatgaa aaagaacttg
      361 ataaagaatt taaagaaatc aatgacttat tactataatt gatttatacg actcattttt
      421 gagtcgtcag actgcaaaca acactctaaa tttaggagtt tgtctacagt ctgaatagat
      481 tttaaattta ttgtccataa tgttattatg aatttatagc attaagaaaa gagataagac
      541 tttacatttt tttaggaatg taaagtctta tctcttttct taattgtaca attagtatta
      601 tctgcactac tttctaatta aataaatttt tagttattaa cttgattaaa atcagagata
      661 atatcattta attcagtttg aagggttgta acgattaaat ggaaattttc ttcatctgtt
      721 ttattatatg gggatgtttt cgttatatat aacaactttt ctttttcaat tttcattaat
      781 aactctgtcg aagtctgtac tttatcttga taattaaatg cagacatacc actttgtata
      841 attgtaatta ttgctgaagc aattgaaaca atcaatagta aagacctgtg ttcggaagcc
      901 tgatcaatta atattgggat actagctgat aagactattt ttataatatt tccgatacca
      961 attactctat tataaaatcg aatttctttt tttaatctat cgattgtaga atcaatagat
     1021 tcgataaacg ctttttgatc catcattttc tctccaatca ttttattaaa atcattaaca
     1081 aaaatattat aataggattt aagtaagttc taactaatca catataaaaa taaaaaaaca
     1141 tttgtatttt atcaaagttt tattatactt gtcaatttgt gtacatccta aaatataagc
     1201 tatttgttta cttctgtaga atatatactt tgttgttaga taagttgcac atgtttatag
     1261 aatctaaata ataaattttt atgtaccgcc cctcaaagtg aactgaaccc caaaagttga
     1321 actatttaat ggactgtttc cgatattcta ctggagatag tccattaaat agttcaactt
     1381 ttggggttca gttcaaagag ggggggattt tttatcgttg tggaatattt aaataccaac
     1441 gcttgtcatg aaaatcttgt gctccaccct tagtatttcc ttctggatcg tttgtcgcac
     1501 gcatcatgac gtatactttc ttattaggga aatcacgcat attgaaagat acatgatagc
     1561 caacatttcc taaagtatta taagcttgat ttacgtctgg tctataaatc ccatcagctc
     1621 ttactctagc tagttctttt ccagtattgt agtccataat gaaaatatac tcgtatttat
     1681 aattagcaat gtgccatcca gctacatgca agtttgcgtt ttcgatttct ccgaactgat
     1741 caatgtgggc gtaatttgtt ccatctgtca gcgtagaatt tgcagcacct gctcgagttg
     1801 gatcaattac tggtttatcc tccgaagtag ttggattatc atccgtaaaa ccatgagcca
     1861 aatcataggc tagtttttct ttacttacac ccatttcaga aagataaccg taaggatctg
     1921 tatgatcgcc ccaaatattt tgtgttaccc ataaatgcga tttgattcct ggttggttat
     1981 aaggagtgtc taatgttaat ggaataccat atttcattgc tgaatctctt gccaattcaa
     2041 cgtatacttt atagttcttt tcaaaagttt ctttatcatg tgtatgttgt aactcgattt
     2101 gcacaggact tttggctcac gaggttgtcc tactctacat cttgctgata gatatgctga
     2161 aaggaaaaca ccaacattat gttttgcttt ttcagctaga acgagacaag caggaatacc
     2221 tttagaagat atcaaaggtt ttttaggtca taaagatgtt tccactacac aagtctatgc
     2281 ccatatttct cccgaagtga aaaaaagatc aatgaatcaa ctagaaaact atatagaaga
     2341 gcaaataaaa aagcactcaa attgagtgct tttttaagct cactatcact aaaactatca
     2401 ctaattttat ttataagcga acatgtttct atcactgatt ttttaaatct agcgaaaaac
     2461 ccttatctta aaggcgttcg ttcaattctt tggcaaggtc ttcaaagcct ggcttgccta
     2521 gaagtgcgaa catggttttc ttatagctca tgtagaaaaa ttttcttgat gatgatttta
     2581 tccatcaatt gagattgact gttttgctct cctatgattt cagctatgat tgtccgattt
     2641 tgcggttttc ttcttaactg gtagttgatt ttcccagttt ccatcaactc gctaagcata
     2701 tccacgactc cgccaaatcc ggtctttttc gtaataaaac ctagtgctac cattcgttca
     2761 tctagatttt ttgctgtaat cgtcacacca gtaatgagcg agtgctgtaa tgtttgggcc
     2821 agctcttcca tcccttcagc attggatacg acggaagctg ttttgttaat aggttcttcg
     2881 tttatttctt ttggttcttt cctctccact ttcactgttt gacgaaggac atctagttct
     2941 tgcaagagcg tttcgtattg ttcttgggtc agcatcacgc cagctacttt ttcacgatta
     3001 aatatatata cgccagttcc cgcgtctcgc gcttgagcaa atacatccat cggcgatcgt
     3061 ttcacttctg tgatcgaaga tgtgggaact tctaatttct ttaattccaa tggatttcct
     3121 cctttactaa tcgcttttta ttatagcaca gactgacttg ttttgatctt ttttccaaag
     3181 gttttatcgg tttttgccta accagtaatt gatatcggta agaagtcttt cgataccaaa
     3241 tgaaggatgg tacagatacg ttttttgatc ttcgttatgg tctagtggaa aaaaatgatc
     3301 gatgatcact agatctgcat accgaggcgg cttatttcga gtacatacat gtatagagat
     3361 ccgttttcga tgtcttagcg ttttgttcag taccccagca agtcttcttg cttcttggtg
     3421 ttcatagcga aaaaaaaaga cgattttcac ttcaggaggg tggacatcta aataccctcg
     3481 ttcctggagt gttttcagta aaagcatccc ccactctact gcggggtgtg caagtgcttg
     3541 ttggatcgct agccgaaatt gatatagttt atctttggaa ttgggaaatt tttctaatgt
     3601 ttcctgataa taacgaactt cttctatcag ccggtcatgg ataccaatta cgtaacgaag
     3661 tcattcttgg taaagtactt ttgtcagctt tgatttgctt tcgctctcaa attcgctatt
     3721 cagccaaaac agcgaatcaa gcttttcagt cacaatcgtc aatttccgat agtcttgtgt
     3781 ctcttctatc cgtttccacc gcttttcagt aatctggtta cagctcaagc gcaaaattgc
     3841 tagataattt ttttctttta ttggcaaaat ctgctcctct ctaaatagca attcaggaaa
     3901 caattcaaag aatagtgttc gactgtctcc taaaatctcg atttctgccg gatcctttct
     3961 ttgcttcaat aattggatga acatctcaga aaaggactgc tctccatcat ctgcaaaaaa
     4021 atgcggaaaa tctttcaaaa agcaaaacag cagatatctt acttttcttt ctgaaccaaa
     4081 gatctgtgct tttttataag aaaaagaaag gtggtactcg ccaaaccact ttctcaatcg
     4141 ctcttgcgta gaacgatcgt acttctgctc gtaaggttca ttcaatagca gatttttcag
     4201 taaacaaaac gggggtgatt ggatcagaaa aacaaacaag agataaggtt cgctatatcc
     4261 ttgatcataa actaactgaa cggttttctt atgaagaatc agctgaatgg gacagtcgct
     4321 ttccgccaaa cgtttcagat gccgatccac tgttttaaca tcgattttca gttcttcagc
     4381 taaatcagct tttcgccaga tcaaatcttt cattagattg attagtgaaa ataaattctg
     4441 tgcatttttt gataatagtt tttgccatct catcgatcat ttctcacctg atttctaaac
     4501 atattgtttg atcaaaatgg gttcactcct aaaaagataa aaaactccct ttctatttat
     4561 ttaaatacgc aaatcttcct cattattttt tattttactc aatttaatcg tattctcatt
     4621 tcaaaacgaa tgtactttaa aaaaacataa taagatcact ttgcttgtag gatgtattcc
     4681 cttccattac aatgaaataa atagcgattt tatgagaagg tgatgtgaaa atggaagaaa
     4741 aaatagaaga atccaaacaa aaaatcgatc agttgatata agaattagaa aaagcggtca
     4801 tcggcaaacg ttcaactatc caattgatga tcgtggccct attagcaggt ggtcatgtct
     4861 tattcgaaga tattcccggt gtaggtaaaa cgttactggt caaagcacta gcaaaagctg
     4921 tacagggaac cttcagcaga gtccaatgta ctcctgatct gctgcctagt gatattcttg
     4981 gtttttccgt atacaattca caatcaaaag agtttgaatt tcgtccggga ccgatcttta
     5041 ccacgatctt gttagcagat gagatcaatc gtacgactcc tcgtactcag tcagcacttt
     5101 tagaagcaat ggccgagaat catgcaacga tcgacaacaa tacataccct ctagacaatc
     5161 atttttttgt cttagctacg caaaatccaa tcgagtacga aggaacatat cctttgccgg
     5221 aagcacagct cgatcgtttt ttattccgac tacaaatcgg ttatccttct tttgatgacg
     5281 aacttttgct acttttggat aaattcgaaa aagtgttgga taacttaaat gaagtattga
     5341 acagttatga aatagaagaa ataaaaacaa atgtggcgaa tgtctttgtc agtcccgaag
     5401 tggcatctta tgccttgcag ttagtgtcag caacaagaag tcatgctgcc atccagcttg
     5461 gcatcagtcc acgaggaagc ctttccttta ttcaggcagc aaaagcttat gctttaatcc
     5521 atgggagaaa ttacgtcacg cccaaagatt tgcaggattt agttccttac gtgttttccc
     5581 atcgcctgat tttttacgat cgttcattga aggaagacga aaagaaacaa atcattcata
     5641 ctcttgttgc acaaattcct attcctgtga ggtagattga ggtagacaat ggaaaaaatc
     5701 aaagattatt tcattaattt tgtgttattt ctggtatatt tcatcattgt gctttttgct
     5761 cttgtattca acaattcttt aggctggttc ttgttggcct tttttactct ttatgtatca
     5821 tggagcttga tttcattaag cagctttcta aagaaacttt cggttacttg tacattgcag
     5881 ccactcgttt atcgcaaaaa aagtatgcag gttatttttt ccatagcaaa aaagagaact
     5941 ttttctttac ctctccctcg tttacaaatc ggcttcccag caatctttgc agaaaaaaac
     6001 aagagatttt gattcttaca aataaaccgc aagaagtcca attgctttgg cagccaaaag
     6061 aaagaggatg ccatgaaaca ttaactgtca tttttacagc ctatgatagt ctaggacttt
     6121 tcagaaaaag tgcaaaaaga gagatctctt ttcctgtgac tgttctgcct gctttttgta
     6181 agattcaagc agaaaaatta cagagagttc tggaaaaaaa acagcagctg aacgcgtacc
     6241 aaagaggtct tgattttcgg gaacatcgcg cttatcgtcc aggtgattct ttcaaccgaa
     6301 tcgattggaa attgtctgct catactcaag agtggttata ccgtgaatac gattatcaag
     6361 aagaagaatg ttctcctctt ttttgctttt ggggttcgcc cagtccaaaa tttgaacctc
     6421 tgctagactt gtatttttct ttatggcatt tgagaaaaga aaagcagccg gaacttctga
     6481 tattaggcaa ccgcgccttt catggcaaag accccggtca tacctatttt gcttctttgg
     6541 aagctggcga tgagaaagct tttttcgcac acttgaaaaa atatgcaaaa aaacaaatcg
     6601 tcctctttgt tcctgagaat tctcctgaag tctcagaagc tattgaaaca ttgtcaaaag
     6661 atcgaacggt ttatcttgtt tatttcgtag aaaaacaact catggtccaa gaaaaagaca
     6721 agatatgttc attgccagga ggtgaatgga ttgacgatta aacgggaaaa atggctgcgt
     6781 ggcgtttact cctttgtgat actaagtgta ggtgctccga tatttgtagt agctaatcaa
     6841 ttgcaaaaca gctaccttct tatcctaact attggtgtcc tatgccttat tgtctgctgt
     6901 attcctaaaa aatgggtacg tttgctgctt tctttgccag taatgatagg ttgtttgttt
     6961 ttatattttc cttcgaagac attttccata ttatggatct tacagttttt ttcgtcagtc
     7021 acagaggaat tcttccatct atcccaaggt aaactttatt atttgccaga aaagacagct
     7081 ttttttctca taatgttgct gatctattta tttattacat tgaccgtgga ttacgactat
     7141 tggtacgcac cctttctttc tttgatggct tacttcatga tgcttaccgt ttttcggaaa
     7201 aaagatttac tgtacgaaat gattgcggta gtaactgttt tgttcgtgta tctggcagca
     7261 aggcaatttt tctccatccg gttgttgtcg ggaaacactc gattccagtc attgactaca
     7321 gttctgctta tttgtttctt aacttttagc gctatcttgc ctttatatct tccgaaagta
     7381 caccaatctc tcgaggaaac gagtgaaccg atccgagaat atcttaatga tgaagggctt
     7441 tatgacacac tccatgagta tcaattaacc ggaagtgcaa gaacaggctt cagtgagaat
     7501 gatgaacagc ttggtggacc tttatatgat aatggcgaag ttgtttttac agcgaaccaa
     7561 aaaggaaatg gctattggaa gatcgaaaat aaaaatcatt acaccggttc tggatggata
     7621 gaagatcagg acgcacccat ccaaccaatc caagaattcc ctgttgacat cacgagctac
     7681 caaaccgtta tagaagacaa agaaaacatt acattgaccc taaaaaaaca agttttctta
     7741 ccttatcctt atggaaatac taccttgact gatttttcat tagctagtgg acaaacgctt
     7801 tactatttgc ctgaaagcca gcgattcatt cctgtcccga atgaatcgac acgttctgca
     7861 actttacaaa cagaaaggtt agtttttacg agagaagaat taaaaagcag tcagttaaaa
     7921 gctgatgatt tagaaaatca gcagacaaat cttcaattgc caaaaagttt gcctaaacgt
     7981 attgaggact tggcggtcga attgaccaaa aatgaagcaa ctttaattcg taaagtcgaa
     8041 gctgtctaac agtatttaaa aacaagcgga aatttccgct attccaaaac ggataccggg
     8101 catactccaa aagaacacga ttatgtggat tatttcctct ttgattcaaa agtcggctat
     8161 tgtgacaact tttcaacttc tatggtcgtc cttcttcgaa cacttggtat cccagctcgc
     8221 tggacaaaag gttttacaaa tgggctcaga acaggcacag ataatcaagg gaatgaggaa
     8281 tacagcattc tcaatagtca tgctcattct tggccagagg tatactttcc tggatttggc
     8341 tggcttccat ttgaaccaac cccttcattt gccaatccaa tgggttcaca accagttgct
     8401 gaaacaaccg aaaccgtcca gcctgctatc gaacaaccaa atgaaagcga aaatatggca
     8461 gaaactattt ccagtgagag atctgaggtc attccatcag aagaaacaac actcacacca
     8521 gcttataaaa tcgtcttatt cagccttgga gtgtgtttat ccgtcttgtt gttctttcta
     8581 ttgttattca gaaaatctct gcgctggaca agttatctta tctatcttca tttttttgct
     8641 tctactaata cgattgcata tcaaaaactt cttaaccctt tggaaacatt ggtaccgcgc
     8701 aaacccgcag aatctttgca ggaatatagc ctgcgaatag aacaagaatt caagctagat
     8761 ctgcgtttca ttcgattaac tactcaatat gaagcagaaa tatatggacg acaagcagat
     8821 ccggtaaaat tcgataaaaa aacctattta gaaataacgc atataataag aaaaatggta
     8881 tacaaaaaaa ttctgacaaa agggagccgc ttcaaaaaat aagataaaat ttctggagaa
     8941 tctacttctg gaatgccgag aaccagctga ttgagtatcg attactcgaa aaaaaggttg
     9001 tgacacgttt tttgtcacaa ccttttttca ttattatctg attttcaatg tcaaagcatt
     9061 tagagctaca actaccgtac ttaacgacat caagacagca ccaactgctg gacttaatat
     9121 gataccaatt ggcgcaagaa ttccggctgc tagcggaatt gcaagaatat tgtaacctgc
     9181 cccccaccag aggttctgga tcattttctt tcgcgtttgc ttggctagat caagaaaatg
     9241 caaaatatct tttggatcgc tgtttgtcaa tacgacatcc gcagaatcga ttgcgatatc
     9301 tgtccctgca ccgattgcca tcccgattga agcacgggct aaacttggcg catcattgat
     9361 cccatcaccc accatgatta cttttttccc ttggtcaagg tatttctgga caacagcttc
     9421 tttatcatct ggtaataaac cgccataata ttcttcgatc cctaaataat ctgctactgc
     9481 ttgggcagcg tttttattgt caccagtaag catgacagga gtgatttttc tttctttcaa
     9541 tgttcggata aattcttttg cttctgtttt tactacgtca cctaaagcaa cgattgcagc
     9601 tagatgattt tctaaaatca ggaagctgat ggtatttcct tgttcttggt aaggtttcaa
     9661 taatgcttgt tctacgttta atccgagacg ctcaacttct ttttcattaa ctattttcac
     9721 ttgttgtttt ttgactgttg cctctagccc gactcctgaa agatttttta gattttcagc
     9781 ttgataaggc ttgatttcat gttctttcaa ataattcata atgccaacag ccaatggatg
     9841 attggcattc gcttccaagg ctcctagata ttgaaggatt tcatttttat tgaacgcatc
     9901 atcaagtact tcgacacccg ttacagtaaa ttttccttct gttagtgttc ctgttttgtc
     9961 cagcatgatc acatctagat cattggcttg ctccagtgca ttgcggtttt tcaaaagtaa
    10021 tccgttttta gctgctattg atgtggaacg agcaacaact aatgggatag ctaaacctag
    10081 agcatgagga caggcgatga taaagactgt taccatacgt tctaatgcat taggaagatc
    10141 tgtcaagaac aaccaggcga tgaatgccag gatacccaca attaatgcga cataaaacag
    10201 ccattttgcc actttgtcag ataatgactc tagcttggat ttttctcctt gtgcttttcg
    10261 caccatttcc ataaccttcg ctagataacc attttcacca gttccagtta cttcgatttc
    10321 gatcgttcca tccccattga tagaaccgcc aatcactttg tcattggctt gttttttgat
    10381 tcctcttgat tcgccagtca cagctgattc gtcaacaatt gtttcacctt tcaagattac
    10441 accatctgtt ggcattttat caccagaccg gacgatcaaa cgatcacctt cgtttacttc
    10501 tttcaatgaa actgtctctt cttttccatc tttcgtcaag cgtttcactg attctggcag
    10561 taattctgct agtttttgta aagcattgct ggcattcgac acagcattca tttcaatcca
    10621 gtgacctagt agcataataa cgatcaaagt agccaattcc cagaagaaat ccatgacgtg
    10681 tgtatgtgga ttgagcagat ttgcgataaa cgaatagaca ctataaatat atgcaactgt
    10741 aatccccatc gcgatcagtg tcatcatagc aggacttttt tgtttcaatt ccatcttagc
    10801 tccacttaaa aatggctgac cgccatagat aaatagtata gttgctaaga tcaatacgag
    10861 ccaatcagaa ccaggaaacg ttacttgaaa tggaaattcc attcccatca ttggtgaaaa
    10921 aagaatgatt gggatagcta ggataagcga tagccaaaat ttttgtttga aattccccat
    10981 gtgcatggaa tgatccatgc cgccgtgttc gtgatccatg tgcatcgaat ggtccatttg
    11041 tttgctgttt gctatatctc catggttatg tcccatgtgc atggaatgat ccatctgact
    11101 atggtcatgt ttcatctcca tctgtttttc atgagattct gtactttctt tgtttactac
    11161 ttctttttta tgctcatgtt ttttctccat atcgttccca ttcattttta ctccatccct
    11221 tctcttactt tttcatgtgt cgatttaagc acagggagtt caacaataca ctgacggaac
    11281 taaacgccat cgctcctcct gcaatgattg gattcaaaaa gcctagtgcg gcaaaaggaa
    11341 taccaatcgt attatagaca aaagcccaga aaagattttg tttgattttt ctcaatgtca
    11401 acctagacaa ctcgattgtt tgtgcaatgg atgccaaact gctattcatc agcgtcacat
    11461 cggctgtttc catcgcaatg tccgttccac ttcccattgc cataccgaca tcagctaatg
    11521 ctaaggccgg tgcatcattg attccatcgc ctgccatacc gacttttttg ccatctttct
    11581 gaagtttttc tacgtaggct gctttatcct ctggaagtac ttcagcaaag atatgctttg
    11641 gatcaatacc aacttgttta ccaatcgttt cggctgccag tttgttgtct cctgtcagca
    11701 taaaaacatc taatccttta ttctggagct gcttgattgc ttgtttgact tctagtttga
    11761 tttgatcagc cacggcaatc aacccgatca cttgcttttc atcagctaaa aacatgactg
    11821 tttttccctg ctgttctaat tctaacgcgt gttcttggta ttcatcaaat gataggttca
    11881 attcaattaa tcgtttacgt gtacccgcaa aatagcgtac tccgttaatc gtaccgctga
    11941 ttccagcacc tgggtgggct gtaaaatcaa tcatatcgta tgttgctgct tcttgcagtt
    12001 ttccgtattc cacgattgct ttacctagtg gatgttcaga agcttgttct aaagtataaa
    12061 aaatagatag gacttcttta gaaccgacta gatctgtaac tttgggcttt ccttctgtaa
    12121 tcgttccagt tttatccaaa acaatgctgt ctaagtgagc agctgcttct aatgcttctc
    12181 cgcctttaat taaaattcca tttcgtgcac caacacccgt tcctaccata atagctgttg
    12241 gagtcgctaa acctaatgca catggacacg caatgactaa tacagagaca ctatggatca
    12301 atgcgagttg ccaatcacca gtgatcaaac ctgtagctat gagcgtgata aacgcgatga
    12361 ctaatacgat cggaacaaaa atccctgaga tccgatctgc gattttttgg attggggctt
    12421 tgctcccttg agcatcttcc accatttgaa tgatttgcgc taatactgtc tgcttgccga
    12481 cttgtgtaac ttccatgtga agtagaccat tcgtattgat tgtcccgcca aagagcgtgt
    12541 catccggatt cttttctaca ggaagatttt caccagtaag catactttca tctatcgcac
    12601 tgcttcctga aataattcga ccatctgctg gaatctgctc accaggacgg atgactagtt
    12661 gatcaccaac gactacttct tcaatcgcta acgtttcttc tttcccgttt cttatcactt
    12721 gggcggtttt tgtttgaaga gacatcaatt gtttgattgc attacctgtt ttcgtttttg
    12781 ctgtatgttc caaatatttg ccgagcaaaa tcagcgtgat gatcatactg ctgctttcaa
    12841 aataaagatc ttgggggtgt ccacggaaaa atccgttgta aatgctcaat gcaaaggcag
    12901 ccgatgttcc aattgctacc aatacatcca tatttggtgc tttcgtcttg attgcatggt
    12961 acgcaccttt ataaaaacga gcaccgacat aaaattggac aggagcagac agcactaact
    13021 ggacgattgg aaaatgaaaa aagtgaacaa tcgccgcatg gcttcctaac atcatagcaa
    13081 tcattgacaa catcaacggc aaagtcaaaa ccgtactcaa tataagatcg aatagcattt
    13141 ttttcaaata cgcttgcttt tcttctgcaa ttttttgttt gtgggcttca tcgtacaaaa
    13201 ttgcaccata gccgatgttt tctacgcttt ggattaattt ttcagtggtc gtcccttcat
    13261 atttgacact tgctttttca gtggccaagt tgactgtggc attgaccaca ccaggttgtc
    13321 cgttcagctc tttttcgatc ctagcagaac aatttgcaca agtcatacct gtaatgacga
    13381 acgtatccat tttggtttct gctgttgcca tcaaatcacc tctgctttat aacccaatcc
    13441 attgattgct tgacaaatct tttcggattg aacttttgtt tcatcaaact tgaccgtacc
    13501 gtttgctttt ttcaaattta ctttcacttt ttgcacgccg tcaagtgcgc ttactgtttc
    13561 ttctactctt gctgcacaat gattgcagct cataccttcg attgaaaatt gttgtttcat
    13621 tttttcttcc tcctattgat gttgtttaca ttcacattga cctgggatac agttacattc
    13681 gatcgtatct actggttgct tttgttccag ttgtttcaaa atctcattga tatcttcttg
    13741 agtcaaagtg gcttcttcta ctagatccgc aatcgtctct ccaatccttt ttgcacagat
    13801 atgggaaaaa agattttccg tcgcactgcg aactgtttcc atctccgaga cagctggata
    13861 ataaatgaat ttttttcctt cttgttctgt ccagatcact tcttttttta ccaaacgacc
    13921 cagcaaagtt ttgatcgttg ctggtttcca atccatcgaa tcagctaaga tctgcgtgat
    13981 ttcttgggct gtcgtctgtc caagtgtcca aataacacgc atgatctccc actctgaatc
    14041 actgatcttt actggcgttt tgactttttc catttatttc acacctttcg tttacaaatg
    14101 taatcattat cttatgaata cagattacac ttgtaaacaa aaactgtcaa ttatttttgc
    14161 tctctatttt caatttagtt aaaaattctt gtttctctcg tcttgtttta aggatgatca
    14221 gtttatttct tgcattagct acttggatca gctgctgtat tttcggttca ttgttttctt
    14281 caaaatgcca gataaaagat aaaaattcta agtattccct gtttagtttc tccgaaaatg
    14341 attcaggcat atctggccga gattttttgt ttatctttct ttttagagaa cgccaaacta
    14401 ctcggtagat ggcgagataa cgcggcactt taagccaaat gatcttatct gcttctttaa
    14461 tcctttcctc taatgtagaa gtataatttc cttcaacgat ccatgacgga ttagatacca
    14521 taaacaattg ctgttcttgc aaaaaccact tttttgcctg aatactgtag tctgttgtat
    14581 gccataaaag gtctagcggc agtagcggaa agtcggtgat ttctttgatc ttccttgcga
    14641 gggtcgattt tcccgaccca ctttgtccaa tcacgatgat cttcattctt ctccctcact
    14701 tctctttgga atttggttcg atcataccac ttataacgcc gcaaaaaaac aagggactgt
    14761 gacaaaagtc gtgtcaaagt cccttgtttc gaa
//
LOCUS       DAFENC010000056        13851 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.058, whole genome shotgun sequence.
ACCESSION   DAFENC010000056
VERSION     DAFENC010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13851
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.058"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..138)
                     /locus_tag="LP493_002395"
     CDS             complement(<1..138)
                     /locus_tag="LP493_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HBL2134509.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LK"
     gene            complement(369..1499)
                     /locus_tag="LP493_002396"
     CDS             complement(369..1499)
                     /locus_tag="LP493_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBL2134510.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     gene            complement(2040..2246)
                     /locus_tag="LP493_002397"
     CDS             complement(2040..2246)
                     /locus_tag="LP493_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134511.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(2262..2876)
                     /locus_tag="LP493_002398"
     CDS             complement(2262..2876)
                     /locus_tag="LP493_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBL2134512.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(3023..3706)
                     /locus_tag="LP493_002399"
     CDS             complement(3023..3706)
                     /locus_tag="LP493_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBL2134513.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(3815..4273)
                     /locus_tag="LP493_002400"
     CDS             complement(3815..4273)
                     /locus_tag="LP493_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HBL2134514.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(4357..6120)
                     /locus_tag="LP493_002401"
     CDS             complement(4357..6120)
                     /locus_tag="LP493_002401"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBL2134515.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(6341..7801)
                     /locus_tag="LP493_002402"
     CDS             complement(6341..7801)
                     /locus_tag="LP493_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134516.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(8009..8935)
                     /gene="glsA"
                     /locus_tag="LP493_002403"
     CDS             complement(8009..8935)
                     /gene="glsA"
                     /locus_tag="LP493_002403"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBL2134517.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(8958..10385)
                     /locus_tag="LP493_002404"
     CDS             complement(8958..10385)
                     /locus_tag="LP493_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2134518.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(10416..11630)
                     /locus_tag="LP493_002405"
     CDS             complement(10416..11630)
                     /locus_tag="LP493_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HBL2134519.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            complement(11971..12213)
                     /locus_tag="LP493_002406"
     CDS             complement(11971..12213)
                     /locus_tag="LP493_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBL2134520.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(12245..12802)
                     /locus_tag="LP493_002407"
     CDS             complement(12245..12802)
                     /locus_tag="LP493_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBL2134521.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(12815..13003)
                     /locus_tag="LP493_002408"
     CDS             complement(12815..13003)
                     /locus_tag="LP493_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBL2134522.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(13016..13582)
                     /gene="amaP"
                     /locus_tag="LP493_002409"
     CDS             complement(13016..13582)
                     /gene="amaP"
                     /locus_tag="LP493_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBL2134523.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
BASE COUNT         4136 a         2847 c         2263 g         4605 t
ORIGIN      
        1 cttcagttga tcagtatttc ttcggttttt aatcttatct ggtacacaat tgtggtatat
       61 gttagaaaca gttctcataa tttccttgaa tgttataaaa gtatctgtat aatgttcagt
      121 atattttgat gaacgcatat gtagtcctca tttcttggga gttttgagac tactatatgc
      181 gtttttttgt tgatttacca acatgtttag acattttcct ctaggaaaaa attaactagc
      241 accacgggta taatatgatt ttttgagata ctttcattgc gaattcctct ttctaaaaga
      301 acctctcgct tgaaaaataa aagattgtac tttatgataa ttcaaactga gagtttctca
      361 gtttctcttt attgtttttc aggtcgatag agcgccaact cttcggcctg tatctttgaa
      421 gaaatattca acgtgattcc gattcctaaa gaaaggatca gataacttgt tcctccgtag
      481 ctaacaaatg gcaatggcac accagtcatt ggcatcagcc ccgcgatact tcccacgttc
      541 attatcgtct gaacgaatag caaagttccg aatcctaaaa gaaacaatcc agcttgctga
      601 tttttacagc gactgcttaa acaaaagatt ctcatgcata atgagaacaa taagaaaagc
      661 acacacaatg caccgattag cccaagctct tctgtaataa tcgaaaaaat aaaatctgtt
      721 tctgtctctg gaagataccc tttttttgtg atactatttc ctaatccccg cccaaatatg
      781 ccaccattat atagtgcata aaacgaatgg gtcatttgat agcccgcacc atgactatcg
      841 ataaaagaat ctcttaaagt cgcgatcctt tcataagcat gattaaacat ctgtggaagc
      901 caacctttat ttcctaaata taataccccg cctgctgctc caatcagcaa tgcagaaaaa
      961 gtaacgatta gatagatccc ttttttaaat ggaaccgccg ctgcccaaaa tatgacccac
     1021 gcaatcgaaa ggatcatcaa tgctccagca atctttggct gaaataaaat cagaaaagtt
     1081 atacctactg taatcaggaa tggttttttt agatcttttg ggctactatt tccgtcacga
     1141 aaaaaccagc ttaaataaaa aatcaaaaaa agatttgcca gttcagaagg ctggaattga
     1201 atgccaaaca gagagatcca acgttgtgcg ccgttgacag tgacaccgaa tatccctatt
     1261 cttactaata ctaaaaagaa aatcgataag gctaaaccgt atcctgctat tttagggtga
     1321 agtaaatagt gtagtttgac tgaacgagct aagaagatca cgctccaact caaaaatatg
     1381 aaaattagtt gacgcaataa tagacttttt gtattttcat cggcttgcaa taaacgataa
     1441 gaactggcac tgtatacttc taaaagaccg atcatggaca aagtcaaata aggacccaaa
     1501 atccaccaat cgatcttttt tcaccgcatc tcctcctcac acagcaatcc acttgtcagg
     1561 tgaggagcga gtttgtctca tcaaataagt cagtcacaaa aatataaaga aaaggtcaga
     1621 aaccttttcg aacaagaatt ctgacctagc atcatctcat cgtccgagtt ttagcactat
     1681 acaacgtaaa gaaaacattc ttagctattg gaaaaagcct taatccaaca gtttctgttt
     1741 tacccattgg cgactttcga cgtttctggg caacagccta tgtttgtata ggagcctcac
     1801 ctaacaaggt tattactata ttctatttac gagttcatga tagacttttc ctaatgatta
     1861 ggcaatggaa tttgaaatga aatagtgaaa tttaacaatc tttaatattt tttagaaaaa
     1921 aataacaaat aagttgaaag aatcccgttg caaattcttt cagttgcacc aggattcttt
     1981 gataattttt tagttttatg tgttttttta tatgtttttt cacttttcgg aataaatatt
     2041 tatttgttaa agtaattaaa caatccgcta atcgtttgat ctggcatttc tatttcctta
     2101 ccatctaaag taacagtagt aacgacaaaa tggtcttgca atggcggaac ttctaagtac
     2161 tgcccttgca gaaaatcatt cactgtttca tattcttttt tcatttcttt tgaatctgtc
     2221 gatggtttat agcttatttt taacataact agtgctcctt tttattcggg acgtgcaatc
     2281 gtgaaaattt ctcctattgc tgcataatca tttcctgcca aacggcttac agcattcaat
     2341 tttcttggat cgatccttcc tgtcttatca tcatagactg tttcatttaa atgatatttc
     2401 tgtacttcta gcaaaaataa atcagctgtt actttatttt tattccgtat ctcgacatgt
     2461 tcatataagg atgtttcaaa acgaactttt gcttctgtca atgctggtac tgaaatgatt
     2521 actgaatcag ttaaagtcaa gtcagtcagg tacagttcgc tttcctcatt aggcagattg
     2581 gctgctgttt tatttacttc ttctacgttg tcctcatcaa ggatatggat aacagcttct
     2641 cttgtctcaa gaatattctt tgctgtgtct tttactgcat cttgttttct ctggatcgcc
     2701 aaggataaga tgggtcgatt cgaactgacg atattgaagt aactgaaggg tgcgatattc
     2761 actatatctt ttgctgattt agtcgttact actgctactg gtctagggat gactgaacca
     2821 atcagcaact tgtaattttc acgttctgtc aattctgaag gactccgttc aaacatggtt
     2881 tcgccttctt tctataaaat tcgttaaaaa gcagatcttg aagacaaaat gaaaagtaat
     2941 gcttttttca tcttcttaga atctgcttta aactatctat caatttttct tttttgtcaa
     3001 gaatctgtgc cgtgcgtgtt ttttagttat ttgctttact tgcggcttcg acatatcttt
     3061 tagtgatcaa ttgcggacgg gtgataatag atccaactac gactgaaaaa gcacctaatt
     3121 catatgcttt ctctacttgt tcaggagagt cagtatgtcc ttccataatt actgggatat
     3181 cgacttgttc tatgatttga ttcaataaat caaaatcagg tgtctgcgtc tttcgtgaat
     3241 attctgtata gcctgctaaa gtcgtagaca aaagatcaaa accatcttct tgcgcttgaa
     3301 gcgcttcctc aaaagtcgaa atatctgcca tagctaaccg accgtgttcg tgaatcattt
     3361 ggacaagttc agcagttgtt ttttctgtcg gacgtttacg agaagttgca tccagtgcaa
     3421 tgatttctgc ttgcgtctcc aaaagttctt ccacttcttt ttctgtcgca gtaataaaca
     3481 cttctgaccc atcgtaatct cttttgataa tccctattac cggtaaatca acgattcgct
     3541 tgatttcatt gatatcttct gtcgtatttg ctcgaatacc aactgctccg ccttcttttg
     3601 cagccaaagc cattctcccc ataataaaag aactgtgtag cggctcgttt tccaaagctt
     3661 gacaagaaac gacgactccg cctttgattt gttccagtgt atccacaata tctcctccag
     3721 taatgttata taaaaataca gcttcatata aaaatgtaac ccttttctat tcaggagaca
     3781 ataatgagct atttctttca gcagaccttt cttactaaaa gaaaattact tcaaattctt
     3841 cgtatacgac cagcttctct tctgtaaatt ctatgttcaa cgcttcttta taagcatgtt
     3901 taaaaaactc agcatggact ttccgccaat aagctaatgt ccgatcccct tctccttctt
     3961 tccaagcatg ctctttcgtg acttcactaa aaggcaagat ggtcacattt atatttttga
     4021 tgatacaaac tggttcattt tttccattca ggaccacgtc taattgacca acttttggta
     4081 aaggctcatt ctcttgttta tacagatcgt aaccacttga tgtaccagtc tttatctttt
     4141 ttacaactag ttcgctcaac tcgtctgcca ttttttctgt atccccaaat gaaaagaaac
     4201 ctaatttttc tgattgataa ctaggatatt tttcttggaa ctttttgaca tattcttcta
     4261 cttgctgata cataacatcc acccctttgc tttttataat gaaaaaacca tccagatact
     4321 agtataaaca attatctgga tggtgagcat aatgaattat tgaatattca agacacgcag
     4381 actatcttca acgatttgtt ttggtgttaa atgataacgt tcataaagct gccctacagg
     4441 aacgctatcc gtgaattctt tctctgcacc aaaatttaat acgttcattg aagaatcacc
     4501 ataataacga ctgatatttt cgccaaatcc tcctgacaaa ctaccatctt ctaatgtgat
     4561 gactaattcg tgtgtttctt ttaatttatc taatgtttct acgtcatttt ctgtgatcgt
     4621 tcctggattg atcaacgttg cttcgattcc tttttttcta aaagctttta ctgtttcttt
     4681 tcctaattca agaaaaccgc ctaaagctaa aattgctact tttcctccat tatttactgt
     4741 ttgataggct ggaatactat aatcatttgc gatagctgta ccatgttcta caccatgtgt
     4801 aggaattcgg attgctacag gctgcgctgt ttgttcgaac gcccaatcta gcatagagat
     4861 catatcctct tttgttgctg gagcaagata tttgatgttc gggatacttg ataagtaagg
     4921 aatgtcaaat gttccttggt gtgttcggtc actagctgag atcgttccgc caccgactaa
     4981 aataatcact ggattctcgt tgatcgctaa atcatgtgat aattgatcat atgcccgttg
     5041 caagaaagta cttgattgga agacgactgg acgtactccc tgagaagcca aagcagaagc
     5101 gaaagtgata gagtgctgtt cagcgatccc cacgtcaaaa taatgatctg gatgtttttc
     5161 ttggaatgtt ttcagtccaa aggcgcctgg tatcgctgca ttgactgcgg caataggagc
     5221 tgtacttgtt tgcattttct tatccaaata atccatgatg atcatattaa atgtttctcc
     5281 agaagttact tgctttgcct ccccggtgga cagatcaaat ggtacatgcc aatgatattt
     5341 cattttatta tcgattgccg gctgataacc gcgacctttt tccgtatgga cgtgaagtac
     5401 aatcggatga tcaatatctt ttacttcttc aaataaacgg atcaccgttt ccagatcgtt
     5461 tccattatcc acgtaacgat aatcaaatcc cattgcttta aataggttat tgctgctttt
     5521 accgttggtt tgacgaagct cagctaagtt tttatataaa ctgccatgat tctcatcaat
     5581 agacatctca ttatcgttta ctaatacgat tagattggat tgtaaaacac caccattgtt
     5641 caatccttca aaagctaagc caccacttag ggagccgtca ccgataaatg ctaccacatt
     5701 tcctgattct ttcttcagat ctctcgcttt agctaaacct gttgctaagc tgatagatgt
     5761 agatgtgtgc cccactgtaa aatagtcatg tttactttca tgttggttgg aatatccgct
     5821 cacttcacgg taatgtcctt tttcaaaacc attttttcga ccagttaaaa gcttatgacc
     5881 ataagactga tgggaaacat cccaaacgat tttatccttt ggtgaatcaa atacataatg
     5941 aaacgcaatc gttaattcta ctacacctag attcggacca acgtgcccac ctacatcgct
     6001 gtccttttgc aagatttttt ggcgcatctc ttctgccaac tgtttcattt cctcaacaga
     6061 taattttttg acatctgcgg ggctattgat tgcatccaat acatgtaata ctgtactcat
     6121 aatacattct ctcctccgta ctatcttctt ttaatgaaaa tagatttgtt acactttatc
     6181 tattctacta cttagagttg actctaagtc aatagcattt taaaaaaatt tcagagaaag
     6241 cttgttatat aagtagatct tcgcacgaat caggactcaa ataaaaacct tctacagaca
     6301 attaaaaagc tttgtagaag gtctcctaat taaggtctca tcaagaaata tgttttttta
     6361 ataggtgaag ttcctgagca atatgataca aatggatgtt tgcacctttt aatgagattg
     6421 gatagatctt tgtcttttca gtttctaatc cattttgata gctagcagca tcgcacaaaa
     6481 ccactctttt tttcgcacat agacattcat caggcaattc ttctaatgaa cgaaataaaa
     6541 taggatttat ttcagcgatg ccttcttccg catacaaatg aaattgggtt cgataaaaaa
     6601 attgtttgac tgaactttct gaaacaacaa aaatttctat ttcctgtctc cccgcttgtt
     6661 cactgttgat caaagaaaga cttttgacga attttcgaat gaaattttca ttccatctta
     6721 gttggatttg atttttcttt ttccactctt ccaatatttc tacaattttt ccgtacagaa
     6781 gttgttcttt ttctgataga agatagatcc tttccggtaa aaatacttgt ccatctgccc
     6841 acaacgtacg gacaaattgt aaaaaggatt gcttgaaaat aaaattttct gcatcgtcga
     6901 tttcagcgat actaataatc tgtaaaatca attcattcag tgataggtca ttgagaacaa
     6961 aatttttata aacaacttcg aaatcttttc ttaacagctc catgttctca ttggtataat
     7021 ttctactgtt gaacaaagaa aaaatataat agacatcttc ttcttgtaag tctagaattc
     7081 ctttttgctc ttccaatcct tgacagacta attgaaataa cggcttcgtt tctgcgcttt
     7141 tcttatcttc ttctttcagt ccaaggggaa atgcctttct tccgattgcg atctctattc
     7201 ctcgtatgat aaaggacttt tcatcttccg aatatcttct tttaaaaaaa tgagtctcta
     7261 cataatcaat caactcgtta caagcttctt ctacatacgg atttttattt tcatagcctt
     7321 cccaattgac ataacgtact aaagctagca agatgttccg cgagtcaaat tctgggataa
     7381 tgatttcttt atttttcaaa taatcatttt ctttaaaaaa atccaatacg atttttttga
     7441 ttgtatatac tttgctcaaa gaaataaatt caagatcagc cagttctgta ctcgtgaata
     7501 taccattaaa ataataactt aaaaacttta aaaaataaga ttgaccgtac agaaactgtg
     7561 tgagctcaga aagagcaata ccatgtttga atacgagttt atacttatgc ttctctctta
     7621 cttgttcttt tatacaatat tctagacact cggctagact ttctagatcg tgaaggatcg
     7681 ttggtgtagt cacccttaga gaaatagctg tttgttcgat gtctatttct tggaattcaa
     7741 ataattgttc acacagatac acttttctaa atatatttcg ctcgatgtaa ttttccagca
     7801 ttcctgatac acgcctccag tttttcttat gattttattt aatcatatct gtaaatcgta
     7861 tttttgtttc ctttttattt agaaaagccc tttcaaaaac caataaaaaa agaaactggg
     7921 acaaaagtca aacaagctca caatttcagc ctcattgtag gtagctttga gccgtttgga
     7981 cttttacccc agcctctttc aagaatggtt attcaaagat gtcagcgtct agttctttga
     8041 ctacatcttt caacaattgg ataccagctg cgctgttacc aaatggatct agtgccgggc
     8101 tgaagacacc tatgccgtaa cgatttggca cagctgccat caacccgccg cctacaccgc
     8161 tttttgcagg tacaccaaca tggacggaaa actctcctga ttcatcatac aaaccagcag
     8221 ttgtcataat tgatttgacg attgtagcac tttcttcagt aatgatttgt ttgccattcc
     8281 aaggagcaat tcctttattt gccagcacag cagctaattt tgctatgcct gtagcggtga
     8341 cattgaggga gcattgtctg aaataagcat cgagtatctc cggtacgtct ccttcgatca
     8401 tttgattacc tttcatatag taagcaagag agcgattgat atcacctgtt cttgattcag
     8461 aatgatagat ttcttcattc aatgtgatat taggatcatc acagatctct ttcataaatg
     8521 acaagattcg ctcaaatttt tcatctgcat ctttaccggc aatcaacgag gttgttgcaa
     8581 tcgctcctgc attaacaaaa ggattcattg gatgtttgcg atgattgatt tccatattca
     8641 tgatagaatt gaaggcaaaa ccggttggtt ccgtgttgat tgtttgaaag actttttcta
     8701 ttccgttgtc tttgattgct aataacaata cgggaacttt tgacatgctt tcgatggcaa
     8761 agcgcacatc ggcgtctcct ccctcaatca gttgttttgt atccaaatca taaatcgcca
     8821 tacctaattg tttgggatcc acttcagcta atgctggaat gtaatccgcc acttgtcctg
     8881 tttgataata gtggaaattt tttccaatca attgttctaa ttcttttact tccatttgaa
     8941 taaccagctt tcatttttta tttttctgca tgctggaatt tatgacggca tgcgtagatc
     9001 gtaaatggaa taactaagac gataagataa gaaacaatca gaatcgtttc ataaatccca
     9061 tgctgtccag ctgcgatact agcaggtgga acaaatgaga tacaaaaagc aaaaagtgaa
     9121 gtcaaaagac ctaaacaagc aacgattact tttacaactt ttccgcctgg aacctgatag
     9181 gctctttcaa gactgtcatc tttaaaaacc agcttcaaat agcccgcgaa aaacataaag
     9241 tacaacatca ggtagattac aacagtcaat gacatcgctg caagaaatga aagattattc
     9301 cccccgccgc ttaatgtaaa gacggctgcc cagattgttg caacgatccc atttgcgatc
     9361 atcaaatgag caggaacacc gtgtgtgttt tcttttgcaa aatattcagg aagtaatcct
     9421 tcttctgctg ctacgtgaag tgcttttgaa ggagaggtta cccaagaagc aatttctccg
     9481 atgacaccta aacaaacaag aatcgcaaga attttcgcaa tccatgcaag atttggatca
     9541 atgtgtctta ataggaattc taacgattga atcacccctg tattaagaga caaaccatgt
     9601 tgaggtactg tagtagcgac ggtcaatccg ccaaaagtat ctaaaatgat tgccagaata
     9661 accaatacaa acattgctaa tggataatcc tttttagggt tttccatttc atttgcatga
     9721 ctggcagatg tttctacgcc catatatgct aaaataaagg aaacaaaaac aaccagcgta
     9781 ggcaatttcg aaaaatcagg aatcaatgtt ttcatagaca gtatcgtttg tagtggagcg
     9841 cctgaagcga cataatggat ccctaagcca aacaagacta atgctggcaa caagatacca
     9901 gctacaaaac cgatccgagc aatcaatgaa gtgtatttgg ttccttttaa ctgtgagagt
     9961 aaaatagccc agaaaataat caataggatt gccaatttca gatatttatt gttttgtata
    10021 gcaccaatac ccgttgcata ggataatgca ccagttaaga aatacagcat ggtcaagtag
    10081 ccaactgtta tctcaaacca ttggaaaaag attgcggcaa aaccgaatcg ttttcccaat
    10141 gtgcgactga cccaagtata gacaccgcct ttttcccatc ctttcaccgt tgccatctct
    10201 gctgcgcaca atgccacagg gataaaccat agcaaaccgc ctaataacaa gaaaaatact
    10261 aagctgaagc ctgaggtcgc gaatgtggga tattcatata atgaaacgac cattgagatg
    10321 gtcatagcca aaaagccaaa gaacgttaat ttttttgcag gaattttcgt tttgctttgt
    10381 tgcatgaatc ttcctctttt ctatttgaat ttgtttcaat tgagtttgtt gccaaagaag
    10441 aaaaagtcca atccttcttc ttgttcttct tttgtagtag tgatcgttgt aaagtgcatc
    10501 gccgatttta aaatcactgt tgtcagcaca taggcataca cggcagtaat gatgacacca
    10561 atcacttgaa tccctaagaa gtaccagctg cttggattcg ttagtaaatg gctgttagat
    10621 gcaaagatcc ctatcagaat cgtacctgtg aatccgccca tgccatgaac accccacaca
    10681 tcaagtgcat catcccattg tttcttttta cgaaaatcaa cagcagcatg acagacgata
    10741 cccgcaatga tcccaatcag catggcactt tttgcttcta cataaccggc acaaggcgta
    10801 atggctgcca atccagcaac ggatcctgtt agtacgtcga caaaatcaaa gccatttcct
    10861 tttacttttg caatgatcag ccaagtaatc atcgcaaatg caagagcgat gaatgttgaa
    10921 ccaaatgcat tgactgcttg ttcatctgct cgaagtgcac caccggaatt aaaaccgaac
    10981 cagccaaacc aaagcagtcc tgtaccgata gcagctgcca taagactgct atgctgactt
    11041 ctttctccta aaggaatctt tctttgacca agtgtgagga tacatgctaa agagccgaat
    11101 ccagctgtcg tgtggatgac tgctccacca gcgaaatctc taaatcccat ctgatccaaa
    11161 aatccgccac cccatatcca gtggcaaaca gggaaataaa tcagcagatt ccaaaaaata
    11221 acaagtataa tatagccttt taaattcaat ctccctgcaa aagctcctgt catcaaagga
    11281 acggtaatca cgataaacat cagttggtaa agaaagaaca ttaaaaatgg aatcgttgca
    11341 ccatgaaaca tgttggggaa gcttgtaaca tgtctcatca aaaagaaatc tgccgggttt
    11401 ccaataacac cgccgatatc ccgtccaaag gccaatccga atccaccaaa tacccacata
    11461 atcgttgtta tcccaacgga gagaaaagat tgagacatga tcgttagtat attattcttc
    11521 cgtgctaatc cgccgtaaaa aaaagctaga ccaggagtca tcaggcaaac cattgctgta
    11581 cataaaatca tgaatgctgt atctcctgta ttgataggta atgtattcat ttttttcgcc
    11641 tcctttctac gattacgagt ataaaagaag gtgtagttgt ttttttcttc tgtttttttg
    11701 aattaatact tgcatttata aaagacagac aattaataaa agcttgatgt gttgtgctct
    11761 ttttcgtttt tcacacaaat aaagacaaaa aataaacggt cttcttttta tagaaaaccg
    11821 tttattttcg tcttttttta tttttaaaga tattttttca taaggaataa agaatacttc
    11881 atataaaata tataaaaaag aaccgcagcg agtgtcgcta cggttctcaa atttgttctt
    11941 catttcaaca taagtttttc ttcaatttgc ttataattta cgtgcaaaga atgaaacgac
    12001 taatactaaa atgattgcac cgatcaatga tggaatgata gccattcctg caattgttgg
    12061 tccccaagtt cctagtaaag cttgtccaat tgctgaacct actaaaccag caatgatgtt
    12121 tgcgatgatc cccattgatg atcctttatt cgtgattgct cctgcaattg ctccaatgat
    12181 accgccgacg attaatgccc aaataaatcc cattttaaat tcctcctaac tgacttctta
    12241 cttcttattg tacacgtggt tcgttatttt ctttgacttt ttgtgcacct ttgcctacag
    12301 cagattttgc tttatctgtt tggcgtgaag caaattgtcc tgtggatttt gctgcttctg
    12361 ttactttgtc ttgtactgtt tcttgatctt tttggtattc ttcttgtgtt ttgatgtctg
    12421 caacattcac attcacttcg ataacatcta aatgtgtcat attgtttact tcagtactga
    12481 tcaattcttt gatttggttg taaatatctt cgatgtcttt accgtattct acgatcacat
    12541 ctagatccac agctacttgt ttcttaccta cttctgtatt gatacctgct gttacgttat
    12601 ctgtgttgac taatttttca gccatatttg agaaaaatcc gccatctaat gtcaatagac
    12661 catctacatc tttcaatgca taaccgatga ttttttggat gactttgtct tcataagtca
    12721 attcaccatt catcatgcgg ttttctcctt tttcatttgc caaaactgat ccatttgttg
    12781 tattcatgtt tttgttttcc atctttgttt cctcctatga tttaaaaaat tgatcaacta
    12841 ttcctgactg tttcaaataa aaaccgattc ctgcgccaat tgctgtcatg attatgatca
    12901 acaatgtctt gaaaaatcca atcgttaacc ataaaacagc tagcagtagt ccaagacccc
    12961 caaagataat agggagcttg tatgctgaaa atagttcttt cattatttgg ccctcctatt
    13021 ccactcgaga gtgcttgtag tctcttgtat cttcttgttc ttcataaccg ctgtatgtga
    13081 ctgccacttt gaccgtttct tttgttccga gtactttagt tacttcttct tcgatatctt
    13141 gcatcaatac acctgttttc cctactaatg aagaagttcg tttcaagtct ccgttgacat
    13201 ggatatggat tcgatttttc gttgaacgta tccgtacttt aggtgaatga atgaactctt
    13261 cttcgtgtaa atgggaacgt accaaccctt cgatcgcttt tttgtcgatt gttagtttgc
    13321 catcttcccg tttcataacg aaagttcctc ttgactttgg atagaaaaga acgactagca
    13381 agatgataat agcaagaacg gcaaatacta cagctgccca gaaaatatat tgttgcatgt
    13441 agtaattcgt taaagtaaag aagcgaaatc gttccaattg ttcaggcata atatacggcg
    13501 cattgatcaa cgcaatcgct agaaatactg aaagtagcag taaactcatg ataacaccga
    13561 ttatttttaa ccccttattc attttccacc tcctataaac ttatttttac cctgtaaata
    13621 actctaccga caatcacagt atagatagcg aacagttagc atagcatcag taaataaagc
    13681 gctaccaaac attgctggat cataacggcg ttttattgcc agtctgatac tgaaataaca
    13741 attgcttact tattctctat ttacttttga ttgctggcta tacttaaagg atattattca
    13801 agattaaaaa ttgcaaagat tatgctcagt tattattaca agattctatt t
//
LOCUS       DAFENC010000057        13511 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.059, whole genome shotgun sequence.
ACCESSION   DAFENC010000057
VERSION     DAFENC010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13511
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.059"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            269..3058
                     /locus_tag="LP493_002410"
     CDS             269..3058
                     /locus_tag="LP493_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBL2134524.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLVQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            3105..3632
                     /locus_tag="LP493_002411"
     CDS             3105..3632
                     /locus_tag="LP493_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HBL2134525.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            3653..4843
                     /locus_tag="LP493_002412"
     CDS             3653..4843
                     /locus_tag="LP493_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBL2134526.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            4883..6181
                     /gene="asnS"
                     /locus_tag="LP493_002413"
     CDS             4883..6181
                     /gene="asnS"
                     /locus_tag="LP493_002413"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HBL2134527.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            7357..8031
                     /locus_tag="LP493_002414"
     CDS             7357..8031
                     /locus_tag="LP493_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBL2134528.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     KFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            8028..8369
                     /locus_tag="LP493_002415"
     CDS             8028..8369
                     /locus_tag="LP493_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134529.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERVDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            8399..8758
                     /locus_tag="LP493_002416"
     CDS             8399..8758
                     /locus_tag="LP493_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HBL2134530.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            9283..11367
                     /gene="cadA"
                     /locus_tag="LP493_002417"
     CDS             9283..11367
                     /gene="cadA"
                     /locus_tag="LP493_002417"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBL2134531.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKKFMQYIASAEQFSTHPIAQSVLEGYAGPLLP
                     TTNIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPLSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKKEDE"
     gene            11658..13124
                     /locus_tag="LP493_002418"
     CDS             11658..13124
                     /locus_tag="LP493_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2134532.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
BASE COUNT         4469 a         2344 c         2917 g         3781 t
ORIGIN      
        1 gactcctttg gtagggtgac gttttggtcg actaaatttt accaaaagtg agtctctttt
       61 tgagttgaaa cgaagaaaaa agtgttagta gaaaatcgct ttcgattttc caccaacaca
      121 aaatattata gaaccaaaaa taaacgccca gacatttgcg tgtctgggcg tttttgtcta
      181 ttttctttaa aaagcgatga gagtattttt ctgcactttg tagtataatt tcaaaagaac
      241 attagaggca ggagaagagg aagatatttt gaaaccaaga acttatgcag tcgttgatat
      301 cgaaacgact gggacgaatc caaaagaaga tcggatcatc caatttggct gcgtcatgat
      361 tgaatcaggt cggatcactt cacgtttttc gatcgatatt catccagggc ggaagatttc
      421 aaaacaaatc cagcatttaa cagggatcac gaatcaacgc gtccaaaaag cgccttattt
      481 cgaagatgtc gcccaaacga tttacaatct tttggcagac accatatttg tcgcgcataa
      541 tatttatttt gattataatt ttttgaacca tgaactcatg cgatgcggac ttcctagttt
      601 gaagatacca ggcatcgata cagtagaact tgcacaaatt ttcttgccga cggaaccaag
      661 ctttcgctta gctgatttgt cagaaagcct tggatttatt catgagaatc ctcatcaggc
      721 agatagtgat gccgaagtga caggtcaact tcttttgctg atcgaagaac ggatgagaaa
      781 attgccaatc atcacgttag agcagattgc gcgattaagt agacacacag gtatggatac
      841 gagtcgtttc atttatcatg tgattgaaga aatgaaagaa aaaccagagc cacttgatcc
      901 ctcattagaa atcgtcgatg ggctagcttt gcagaaaaaa gaagtggaac tattcacatc
      961 cgtccattat ggcgagcgga catatccaag aaaaaaacaa gcaaaagaaa aaatgtttgg
     1021 taaaacactg atgtatcgaa aagaacagaa cagactgatg aatgcggtct acgaccattt
     1081 cacaaaagat gaatcaaaag atttgatgat cgaagcagct acaggaatgg gtaaaacaat
     1141 cggttatctg ctgccattga gttatttggc tacacctgaa aaacccgctg tcatcagtac
     1201 cgtttcgcta gttttgcagc agcagatcat agaaaaagac attccattgc tgaatcaatt
     1261 gctagatcag cccatacaac ctgtaattat caaaagctat cgccactata ttgatttgca
     1321 gcgttttaaa ggcacacttg tggaaccgcc agaacaaaaa caatatgctt tgtatcaaat
     1381 ggcggtctta gtttggctga cgcaaacgaa gactggtgat ttggatgaat tacatttaac
     1441 aaatttgaac cattcattct ttgcagatat cgcgcacaga ggtattggat ttttagcaag
     1501 aaatcagtca ttttacgaac aagactttgt tcgtttcttg caaaagaaaa tcaggcaaag
     1561 taattttttg attgtcaatc atgcgttttt agtacaagaa acacagcgaa aagaaccatt
     1621 gcttccagct agtccatttt tgttgatcga tgaagtacat catttgccgg aaatcgctga
     1681 aaaagtaaat gacaaacgat taagtattaa ctatttccat aaacaaatcc agcaattaga
     1741 agaaccaaat cagctgtttg accgaataca aagctattta ccgaaagaac atgaagcctt
     1801 acgctggtta tcgatttatc gagaagaact ttctgcgcta tgcgaagcac agatttgtat
     1861 ggcagaagga ttaatgagtt tagtgagcgg caagcaacct aacggacagt atccagaaga
     1921 agtcatgatg acaaaagaga tgttggatca gctgccactg gaatctggga cagccattga
     1981 tcacctgcag cttttttatc aggagatcca gcagctacag tcacaaatgc gtctgacttt
     2041 tgagattatc caagaaagct ggacaaacca gatgcggatc gatttagcaa gtttatatag
     2101 cctatttgat caattagaca agcaatactt gctgatggat caatggctgg aagactggcg
     2161 agatcatttg atccattggt tcgttcctgg gaacacagcg cagcagatga tttttcatct
     2221 ccatgatttt caagcggcta tgttgccgtc gactgtttgg tatcctcgat atgatcgtat
     2281 tctttatatt ggaggaacgc tgaagatcgg ccctaatcga cactatctct ctaagaggct
     2341 tggcattgaa gcagcacctc ttaaagtgat tgcctctcct tatgattatg agaaacaggc
     2401 aaggatctat gtgccaaaag aggcacctgc cgtccatcaa gtcagcaatc aagcatatat
     2461 cgattattta gagacagcac ttacaggtct gatcgaacaa gaagatcggc caatacttgt
     2521 gttattcact tctcatgatg ttttgcagaa ggtctatcag aaaatgcatc tgtctatgct
     2581 agaaaaagga cgagaaatac tagctcaagg gtttggtgga agccgggaga agcttttgaa
     2641 acgcttcatt ttgtcagaaa aaagcgtatt gtttggcgct gacagctttt gggaaggtgt
     2701 agatttgcct ggagatgctt tgcagatcgt tgtagtcaca cgtttaccct tcgataatcc
     2761 gcttcgcccg atggtcaaag ctaggaacgc ttatttagaa tcagagggga tcaatccttt
     2821 ttaccaggaa tccgtaccta aagcagcttt gaagttacgc caagcattag gtcgcttgat
     2881 aaggacggag acagatcgtg gcgtattgct tattttggat cgaagactag tcactgcaaa
     2941 atatggcgca cggatcatcc atgcattacc gaaaaaagta ccgatcaaag agctagctat
     3001 ggaggaaatc tatcaggata tccatgaatt cttaaagaaa aatgaagaag gaagttagag
     3061 gagctgtctt ttttcataat taaaatctgc tataatgaaa aggaatgaag ataaaggagc
     3121 gacgaccctt gaagaaaaaa cagacaaagg aaaaaacgat taatcgcgtg ttacttggct
     3181 tgatcgtatt tttattagcg gtcatcgtga tcagctcgat tttttacttg cgttccagtc
     3241 gtccggcggt gcaggcgaag aaagaagcag tagaaatcgc aaagaaatat gcaaatcttg
     3301 aggaaaccga tcatttttat tggtttactc gaaagaagac atacttttca ctgacaggta
     3361 caaatgataa aggaaaagaa atcgccgtta tcattcctaa atctggtgaa aaagtaaaag
     3421 tattggatca aacaaaggga ctgactgaaa acgaagcaaa acagacaatt gctgcggccc
     3481 atcctgaaat ccaaatcgaa aaagctgctt tagggatgta tgatgatcag cctgtgtggg
     3541 aagtagtagg aaaagaaaca aatgggaaac tgaattatta cctgattggc tttgaatctg
     3601 gagatgaagt caagacaatc aagggaattt aaaaggtaaa ggaatgaatg ggatggagtt
     3661 atcaaaaaga acaaaacgat tagaaccgtc tgtcactttg gcagctgcgg caaaggccaa
     3721 ggcattaaaa gcaaaaggca gagatgtgct gagtttgact gtgggagaac cggattttgc
     3781 gacaccagaa aacatccaag aagcagcaat cgaagcaatc cgcaatggga aagctagcta
     3841 ttatacacca acagcaggaa tcccagagct tcgacaggca atcgttgatt atctgaagaa
     3901 aaactatgga cttgtctatg aaccttcaca aacagtcgta acagacggag cgaaatttgc
     3961 tttgtatacc cttttccaaa cgatccttga cccgcaagat gaagtcatca ttcctgtgcc
     4021 ttactgggtc agttacggtg agcaagtaaa actggcagaa ggacttcctg tctttgtgaa
     4081 aggggaagaa tccaatagct ggaaagttac tgttgaacag ctagaacaag cacgttcaga
     4141 aaaaacaaaa gccgtaatca tcaattctcc atcgaatccg actggaatga tttatagcaa
     4201 gaatgaactg caggcaatcg gtgaatgggc agtaaaaaat gatattttga tagttgctga
     4261 tgatatttat ggccgtttag tttataatgg caatgagttt actccaattg caacgatttc
     4321 agaagcaatc aaaaatcaga ccatcatcat caacggcgtg tctaaaacat atgcgatgac
     4381 aggctggcgc attggttatg cggtgggaaa tcctgtgatc atcaatggaa tgatcgctgt
     4441 tgcttcccaa tcaactagca atccgacagc agtcagtcaa tatgcagctg ttgaagcatt
     4501 gaaaggtgag caagatacag tagaagaaat gcggaacgcc tttgaagaac gcctgaatac
     4561 gttatatccg cttgtggcag aactgccggg tgtttctctt gaaaagccgc aaggagcttt
     4621 ctatcttttt cctaatgtaa aagaaacgct acgcatgtgt aagtatgaaa atgtcacaca
     4681 atgggtagaa gatcttttag aagaaacagg ggtagcgctt gtgactggcg aaggctttgg
     4741 ggcaccagaa aatgtccgca tgagttatgc cactgatcgc gctacgttag aagaagcggt
     4801 acgcagaatc aagcaattta ttgagagtaa aagtcaaaat taatcctgaa gaaattcaag
     4861 gaatataaaa ggagagtcat acgtggaaca aattcaaatc atcgattcga aaaaccatgt
     4921 gggagaaaca gtaacaatcg gcgcttgggt cgcaaataag cgatcaagcg gaaaaatcgc
     4981 atttttacaa ttaagagacg gaacagcctt tttccaaggt gtagttgtaa aaagcgaagt
     5041 gtcggaagaa gttttccaaa cagctaaaaa tctacaccaa gaaacatccg tgttagtaac
     5101 tggagaaatc cgtgaagaca gtcgttcaaa atttggttat gaaatcggaa ttacaaatgt
     5161 ggaagtggta agcgagagcc acgattatcc gatcacacca aaagaacacg gaacagattt
     5221 cttgatggat catcgtcatt tatggctgcg ttcttcaaga caacatgcga ttatgcagat
     5281 cagaaatgaa atcattcgtg caacgtatga attctttaat caacatcatt ttgtcaaaat
     5341 cgatccgccg atcttgactg gttctgcacc agaaggcact acggatctat tcgaaacaaa
     5401 ttactttgat caaaaagctt atttatctca aagtggccaa ttatacatgg aagctgctgc
     5461 tatggctttc ggaaaagtct tttcattcgg tccgactttc cgtgctgaaa aatcaaaaac
     5521 acgacgtcat ttgatcgaat tctggatgat cgaaccagaa atggctttca ctcatcaaga
     5581 agaaagttta gaagtacagg aacaatatgt agcattctta gtacaaaatg ttttagatca
     5641 ttgcgaatat gcattagatg tactaggacg agacaaagaa gtcttaaaaa cttatacaaa
     5701 attgccattc cctcgtatta cttacgatga tgcaatcgaa ttactgaaga aaaatggatt
     5761 tgatgacatc gaatggggcg aagactttgg ttcacctcat gaaacgttca ttgcgaattc
     5821 attcgaacag cctgtcttta tcctaaacta tccaaaagcc atcaagccat tctacatgaa
     5881 accacatcca acaagagaag acgtggtaat ttgtgcagat atgatcgcac cagaaggtta
     5941 cggtgaaatt attggcggaa gcgaacgggc aacagactat gatttcttgc tagaacaaat
     6001 ccgtaatcac ggtttggatg aaaaagaata ttcatggtat cttgatctac gtaaatacgg
     6061 ttctgttccg cactctggtt ttggtctagg ccttgaacga acagtcactt ggattgctgg
     6121 tatcgaccat gtacgtgaag ctattccatt cccacgtttg ttgaaccgaa tttatccata
     6181 agaggtgatg aaaaagctgt tctgcatcaa gtaattagaa cagccaagca aaaacagctg
     6241 ttcatgtttt tgaattggcg ggacttatta ccgcagatgt aagcttttga ataccgttta
     6301 gtggagaggt tgtgaaaaag ctgtttagtt tcgagtatta agaaaaattt tgtggaaatg
     6361 gctttccaca tttttgcata aatttggctt aataccgaga aactggcttt tgaacaccgt
     6421 ttaaggaaga ggttgtgaaa tcagtgcctt gacctgagta ttagagaaac aaaacggaaa
     6481 aatagcttct catattttac cgttttttta gctaatatcg agggtcagct gattgaacac
     6541 cgtttatatc aagaggttgt gcgcctgccg ttcagctccg agtcacaagg agtaatttca
     6601 aaaaacagtt tttcatgttt gatgactatt gtgacttgtg accgaggagt tggccggaga
     6661 gcaacgttta tttaaaaaaa agaactgcga actctcgcag ttcttttttt aaaatacggg
     6721 ataaaggaag tttccagcag acaagagaag aaagcaaaag aaattgctat ttgattcaca
     6781 aggttctata acgaaatcgc aatcaatcaa acatatacaa agaaggttat tcaaatggaa
     6841 atctgatttg atgatgcttc tgctgttgaa ataaagcagc atctagtacc tgaaaacaaa
     6901 ctaatagtaa cattcgaaga tggagtaggt ccgtattttc agcatgcaat gatccatatg
     6961 taagtttaat tcatccttga aatcatcgga ccagataaag ttatgaccaa tctatcccaa
     7021 gcaatctaga agagatatta gtaaaagaac atttactgga agtcttagat gagcctataa
     7081 atatatgttc tgatggcgtc atcagtggtc tgattgacgg aagcttaggt gtgatcgatt
     7141 tctctggacc aaacaacgaa ggaatcaagg ggaatccggc acgttaagaa aaaaagtata
     7201 aaaaactaga cacttgatga gcgttcattc aattgattga agggactagg ctggtgtcat
     7261 tttttataca tatattttct ctttcgtctt gatagggctt atgggataat ataaggaaga
     7321 aaatcatcgt tttattcaaa aaggagtttt tgacaaatga aaaaacgtat attatttatc
     7381 ggtgacagca ttacagacgc aggaagagac cgagcagaag caactgatct aggtaaaggt
     7441 tatccacttt tgattgccgg aaaactaatc tcccaatatc caacgatgaa atttgaatgc
     7501 atgaaccgtg ggataggagg agacaaaatt gcagatctgc aagtacgctg gcaagaagat
     7561 tgtttagctt tacaacctga ctatgtatcg attttgatcg gaatcaatga tacctggcat
     7621 aatactagcg atcaggctat attcggaact gagaaatctg cgcagcaatt tgaatccgtt
     7681 tatcgaaaat tactaaatga acttcaaaca gcggaaatct gcaacatcat cttgatggag
     7741 ccgtttgtac ttcctataac cgacgaccgt catggctggc gtaaagactt agaccctaaa
     7801 atccaaattg ttcgtaaact tgctaaggaa tatggcgcat tgctggttcc tttagatggc
     7861 atattcaatg ctttagggat tgcttatggt ttttcgaaat atacaagaga agatggggtc
     7921 cacccaacga ttggcggaca tgagatcatt gcacaaagct ggatagatgc aattgccgca
     7981 gtcgattttt ttagtggaga taaaaatgag cgaaagaaaa gtgagaaatg atggaaatac
     8041 ggtgggcagt aaaagaagat ttacctcaaa tcaatcagct gattactgat catccagaat
     8101 cattcgtaaa agcaaaaacg gcagctgacc taaatgataa gaataaacta ttgctcgttg
     8161 ctgtaacaaa agaaaaacgg attatcggat ttgcgcaagc ggacgtgcaa cagtcagaag
     8221 aacgggtgga tcagcgacca tcaggaaaac taatccaaca cacattagta acaaaagaaa
     8281 atacggaaga aatccaaaaa aaatttgcag aatacttgat gctggaagct aaaaaaagaa
     8341 gaataaaatc aatttttgcc cagttttaat caaaaacagt aatagaagga gaaatacaat
     8401 gagttgttta ggaaatgtca tctggtttat attcggcgga ctaatcggtg gtcttagctg
     8461 gttagcagcg gggatacttt ggtgtatcac gatcataggt atcccaatcg gtatgcaatg
     8521 ttttaagatc gcctcccttt cttttgcgcc ttttggcaaa gaagtaattt atcaccagtc
     8581 tggcatgtca ttgatcgtta atatcatctg gctgatcgtt tcaggcctac caattgctct
     8641 cgcacatgtc gtcagcggca tccttctatg tatcacgatc atagggatac cttttgccaa
     8701 gcaatctttc aaacttgctc gattggcgtt gatgccattc ggtgcagaaa ttgtataaaa
     8761 agagaataat aaaggttaga aaacgcatag agtcaggtgg gatacatgta tttcacctga
     8821 ctctatgtgt tttcctgtat aagttctccc atgtgacttt tacgtctttt atttatatgg
     8881 gattactgtt tatggaaagt tgaaataatt ttcattaaag aactctttct atatttttga
     8941 aagcgtagtg gagcttcgaa tatctgggaa ggacattttg cagggattga aaaaagatat
     9001 tgtcctatcg aaaaattaat gaatttagac aaattgccag caacaggctt caaacttagt
     9061 tgctatcctg tcaagatcaa gaaggcaagt gcgggttgga taagagcagg ggcaatgatc
     9121 gaagagaaaa agaaagaata agccaaaaca tctgtatgga agaaattttc cgatgcagat
     9181 gtttttcatt ttttctttcg gataccttga catatgaata accattcatt tataattagt
     9241 tatgaagaga tgttcatatg ttgaggcgag gaggtcatta aaatgaaaag ttacagatta
     9301 gaaggtttag attgtgcgaa ctgtgcaatg aaaatcgaaa aaggagttca gaagatcaat
     9361 ggagtcaagg aagcaacggt aaacttcact tctggaaaac taacgattga cgcagaggaa
     9421 gatcatttgg ctacgattga acaagaaaca aaaaaagtag tgaaggaatt agaaccagat
     9481 gtcaaagtaa cagaaataga taaggaaaaa gtatctgaac atggaaatga aaaagagaga
     9541 aatacgctgt tccggatttt attttccctt gcaggtatcg ctttattgct attatttgat
     9601 tttaatgaac caattcgctt gatagggtat ttattgattt atctgctgat aggatatgat
     9661 gtagtgaaga aggcagtgat gaatatcgtc aaaggaaaaa tctttgatga gaattttctt
     9721 atgtctgttg ctacgattgg cgctatgttg atcggtgaat atccagaagc cgtagcagtg
     9781 atgctatttt atcaaatcgg cgagtatttc caaggattgg cagtcagtca ttcaagaaaa
     9841 tcgattcgcg aattgatggc gatccgtcca gaaacagctc acgtgcagac gacggaagga
     9901 ttgatgaccg tgaaccctga agacgtgcag atcggtcagt ttgtacttgt gaagcctggt
     9961 gaacgtgtac cgttagatgg aacgatcatc gaaggagaat cattagtcga tacgtcagca
    10021 cttacaggag aatcagtccc taaatctgta tatgttggtg aaacagtatt aagcggattt
    10081 atcaataaaa ataaaccatt tttagttcaa gtagaaaaat cttatgaaaa ttctactatc
    10141 agcaaattat tagaattagt agaaaatgcc agcagtaaaa aagcaccagc tgaaaatttc
    10201 attactaaat tcgcgcgcta ttacacacca gtcgttgtag gattggccgt tttattagct
    10261 gttttacctc cacttgttgt ttctggagcg gcgttttctg aatggatcta tcgagcattg
    10321 acatttttag tgatctcatg tccatgtgca ttagtgattt ccgtgccact tagtttcttt
    10381 ggcggtatcg gaggcgcaag taaaatcggt gtattagtaa aaggttcaaa ttacttggag
    10441 ttgcttgcgc aaaccgagac agtggtattc gataaaaccg gcacattaac gaaaggtgac
    10501 ttttcgatcc agacgatcga tacaaaaatc gatccaaaga aattcatgca atatattgcg
    10561 agtgcagaac agttttctac acatccgatt gctcaatctg ttttagaagg ctacgcaggt
    10621 ccgcttttac caacaactaa tatccaggaa tttgcaggtg aagggatctt agctgaagtt
    10681 gatggcaaac aagtattagc aggtaatcac aaattgatgg aaagatttga aatctctttt
    10741 cctttaagtc aagaaatcgg tacattgctt tatctagcga tcgatcaaag ttacagtggt
    10801 tatcttgtta ttgcagatac cttgaaagaa gatgccgtag acgcattggt tcaattaaaa
    10861 caggctggtg tgaagaacac agtcatgttg acgggcgact cgaaaaaaat tgctgatcat
    10921 atcgggaagc aagtaggcgt ggacaagata tatagcgaat tgcttcctga agataaagtg
    10981 cagcggttag aggaaatctt acaaagaaac aataaaaaga ccgcatttgt cggagatgga
    11041 atcaacgatg caccggtgct agcaagagca gatgtaggaa tcgcaatggg tggattggga
    11101 agcgatgctg caattgaagc agcagatgta gtcatcatga atgatcaacc atcgaagatt
    11161 gcagaagcaa tccatttagc aaagaaaaca ttgaaaatcg tcaaacaaaa cattgtcttt
    11221 gctattggga taaaaatttt ggtacttgcc ttaggtgctt ttggttttgc atcaatggga
    11281 gatgcagtat ttgcagatgt tggggtgaca gtattagctg ttttgaatgc catgcgaagc
    11341 ttgcatgtaa aaaaagagga cgaatgaacg tcctcttttt tttatatcct tttcttaatg
    11401 aaaaatgtaa agaaaataga taggattata aaataactaa tgtttttaat tttgcagaaa
    11461 attcaaaata gcttgaaatt caataaggtc aatgaaataa aagaaaataa cttatttttt
    11521 tgatggaaaa aatatgaaaa aacgatgtgt attaaataaa agaatacaca cataaaataa
    11581 cactgtcttg taagtttgtt aaaaattgaa tatgattaca tctggataac aaatttttat
    11641 cataaaggag agaacgaatg aacaacaaac aattacgctg gtttactgtt gcgttaattg
    11701 catttaacat ggtttggggc atggggaatg tagttaataa ctatgctcag caaggagtat
    11761 cagttgtcac ctcttggcta ttgattttgg ccatttattt tattccatac gcattgatcg
    11821 ttggacaatt aggatcagcc ttcaaggata gtaaaggagg cgtcagttca tgggtcgaaa
    11881 atacgacatc taataaacga ctggcatact atgccgcttg gacttactgg gtcgtccata
    11941 ttccttattt ggcacaaaag cctcaagcaa ttctgattgc tggtggttgg gcagtccaag
    12001 gaaatggaaa tatcgtaaat acgatgtcag tacaaatggt agcagttatt tcacttatta
    12061 tatttcttgc ctttttatat ttatcaacaa aaggactttc tactttgaaa gtgattggcg
    12121 gactggccgg aacagcgatg ttcgtcatgt cgatcttatt tattctttta gctgtaacgg
    12181 caccgttcat caatccaacg atggaatttg ccacaccaca tatgaatcaa gtgaaaacat
    12241 atattccaac atttgatttc agttatttca caaccgtttc gatgctagta tttgcagttg
    12301 gaggggcgga aaaaatatcc ccttatgtca actctacaag aaatcctgca aaggaatttc
    12361 ctaaagggat gatcttctta gcagcaatgg tagggatttg tgctgtatta ggctcagtcg
    12421 caatgggtat gctgtttgct agtgataata ttcctaaaga cttgatggca aatggggcat
    12481 acagtgcttt tcaaatttta ggtaattact atggtatcgg taactcattg atgatcattt
    12541 acgcattgac aaacatgatt ggacaaatct ccgcattagc cttttcaatt gatgcaccac
    12601 taaaaatctt gttagcagat gcggatccag aatttgtacc aaactggcta cgtaaacgta
    12661 atcgtaaagg tacattggtg aatggttatc ttctgacagg tatactagta ggaatcatta
    12721 ttttgttgcc gatttttggt atcaaagata tgaatgaatt agtaaaatgg ttgacgaact
    12781 tgaactcagt tgtcatgcca atgcgttacc tatgggtgtt cttggcatat atgatgttga
    12841 ataaagctta taagaaattc aattctgaat ataaatttgt taaaaatcca aaaatcggtt
    12901 ttatctttgg tgcttggtgc tttgccttca ctgcgtttgc atgtatccta ggaatggtgc
    12961 caaaagtaga ttatactgct gatcctaaag catggtggtt ccaattattt acgaatatca
    13021 tcacaccaat cgtcttgatc ttattaggta tgatcttgcc agcaattgct cgtcgagaca
    13081 aaaacaaaga aatcactgaa ccagaaacag tggttcagcc ttaaaataga aatacttgtt
    13141 acaagaggtt gtgacagaag tggtcagctt caagaaataa gaaggaattt acgaaaattg
    13201 cttctcaaat ttttgtgaag tttcggcttg tttttcgaag aagctacttc tggaacaccg
    13261 tgaatcagag gttgtgaaaa agctgtcctg catcaagtaa taagaacagc caaacaaaaa
    13321 tagcccctca tatttttcgt ttggctgggc ttattaccgc agatgcaagc tttggaacac
    13381 cgtttaagga agaggttgta aaatcagcga tttgacctga gtattagaga aacaaacgga
    13441 aaaatagctc ctcatatttt gccgcttttt gagctaatgc tgaaggtcag ctgattgaac
    13501 accatttatt c
//
LOCUS       DAFENC010000058        13146 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.060, whole genome shotgun sequence.
ACCESSION   DAFENC010000058
VERSION     DAFENC010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13146
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.060"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(78..150)
                     /locus_tag="LP493_002419"
     tRNA            complement(78..150)
                     /locus_tag="LP493_002419"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(115..117),aa:Lys,seq:ctt)
     gene            531..1100
                     /locus_tag="LP493_002420"
     CDS             531..1100
                     /locus_tag="LP493_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HBL2134533.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1087..1947
                     /locus_tag="LP493_002421"
     CDS             1087..1947
                     /locus_tag="LP493_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBL2134534.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2137..2841
                     /locus_tag="LP493_002422"
     CDS             2137..2841
                     /locus_tag="LP493_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2134535.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2846..4681
                     /gene="walK"
                     /locus_tag="LP493_002423"
     CDS             2846..4681
                     /gene="walK"
                     /locus_tag="LP493_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HBL2134536.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4678..5994
                     /locus_tag="LP493_002424"
     CDS             4678..5994
                     /locus_tag="LP493_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134537.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5995..6864
                     /locus_tag="LP493_002425"
     CDS             5995..6864
                     /locus_tag="LP493_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HBL2134538.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6919..7728
                     /locus_tag="LP493_002426"
     CDS             6919..7728
                     /locus_tag="LP493_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBL2134539.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7831..8460)
                     /locus_tag="LP493_002427"
     CDS             complement(7831..8460)
                     /locus_tag="LP493_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HBL2134540.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8630..9922
                     /locus_tag="LP493_002428"
     CDS             8630..9922
                     /locus_tag="LP493_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2134541.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9998..10660)
                     /locus_tag="LP493_002429"
     CDS             complement(9998..10660)
                     /locus_tag="LP493_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBL2134542.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10885..11169
                     /gene="groES"
                     /locus_tag="LP493_002430"
     CDS             10885..11169
                     /gene="groES"
                     /locus_tag="LP493_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HBL2134543.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11220..12845
                     /gene="groL"
                     /locus_tag="LP493_002431"
     CDS             11220..12845
                     /gene="groL"
                     /locus_tag="LP493_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HBL2134544.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4370 a         2264 c         2833 g         3679 t
ORIGIN      
        1 ataaaaaaag aacagcgtaa atgttttcga aatgctttcg caccaacatt tacctgttcc
       61 gtgggtttgg cacccaatgg gccgtgaggg gctcgaaccc gcgacccgct gattaagagt
      121 cagctgctct accaactgag ctaacggccc gtacaaaaag tacttaataa tagtagcact
      181 aagaatttta aaatgcaaga ctacatttaa agaaaatcag aaaaatcttt acttccttat
      241 aggaaatcat tcatagatta ttcacatttg ctcgctatta tataagcata ccaacaaaca
      301 aagttcttgc aagagaacaa accctaacac ttttttcatt ttttactcct ttcccgccgt
      361 ctccccggcg ggtctcctgt tcttaacgat aaaagacaag aaggcttagc cttcttgttt
      421 tttgttttca tggaatcccg ctaatcaaat cacctagtta aagcaactag attgaatgtt
      481 tatcataagt ctgatatcat gtttatgaaa tgaaaaaagg agcggttatg atggaaaaaa
      541 tgcgtcagca attaatggag tgggggaagg aactagaaac attccgtctg cctcactggg
      601 aagaactccc tgacttagaa ctttatatgg accaagtcag aacgttagtt gatcgttatc
      661 tttcacctgt gatacaagga gaaaagcatc cattgcttac ctcttctatg gtaaacaatt
      721 acgttaaact aggtttgata ccagcaccag ttaaaaaaag atataacaaa gaacacgtag
      781 catttttact tgcaatcact acgttgaaac aagtattgac tattcctgaa atcaaagaag
      841 ggatattgtt ccaaggaaaa acagtaggaa ttcgtgaagc ctataatcta ttttgcgatg
      901 aacaagaagc agctgtgtgg atggtcagcc aattagcaca aggtaaatct catccgcaaa
      961 aattcgacca ggcaacccct gtagaatata ttgctgtaag agcggcaact ttatcgtttg
     1021 caatgaaact tcttgcggaa aaaacgattg ttctagaaac cgaatattta aaagaggaga
     1081 aaacaaatga aaaacaataa aatcgcaatt ttagtagatt caggtacgga tgtgccagaa
     1141 gaattgataa aaaaatacga gatgtatatg atcccattga aaattattta taaagatcag
     1201 gtatatacag ataaaattga cattacctct gaagagatct atcaacgttt gccagaggaa
     1261 atccctggta catctttgcc ggatggtgag tcgatcacag aaatctttga gcaaatcaaa
     1321 aaagacggtt atgaaaaggt acttgcggta acaatttcca gtggattgag cgggacatat
     1381 aatgtggttc gtttaattgc acaacagcaa gaagaattgg aagcatatgt actagatacg
     1441 aaaaatattg gtattggtgc aggtttttct gcgatccaag cagcaaaatg gctggaagaa
     1501 ggagtagaat gggatcaact gatcagtaat ctgaatgagt tagtcgaaag aacaaaagtt
     1561 ttctttaatg ttgcgacatt ggaatatctt caaaaaggtg gacggatcgg tttagttgct
     1621 tctattgtag gaaccgcttt aaagcttaac ccaatcatct catgtaatga agaagggatt
     1681 tattacacag taggaaaagc taggggacgt aaaaaaagtt tggataaaac ggttgcttac
     1741 gtcaaagaaa aaatcggtaa tgcaaaggtc ttcaacttag ctgttgccca tggggatgcg
     1801 aaagaagaag caattgaaat ggaagcgaga cttaaaagag agttcccaca agcaaaccaa
     1861 atctactttg gccagatttc tccggcatta gtagtccaca ctggtccggg attattgggt
     1921 gtcggtgtac aagttttaga aggataaatc aaaaaaagga aacactgagg tgaaaatcag
     1981 tgttttcctt ttttattgaa gttagaacaa aaaataataa agtattttgc actttcattt
     2041 taattttctc ttttgtttta taggcaaaga tgaaacaaaa gcagaaatac ggtataatga
     2101 gaaggtatga caataatata taagaggtgg ctctttatga aaaaagtttt agttgtcgat
     2161 gatgagaagc cgatttcgga tatcgtcaaa ttcaatttag ccaaagaagg ctatgatgtt
     2221 tatactgcat atgatgggga agaagccttg gaaaaagttg ctgaggtaga acctgatttg
     2281 attttacttg atttgatgct acctaaaatg gacggcttag aagttgctcg tgaggtacgc
     2341 aaaacttatg atatgccgat cattatggta acagccaaag attctgaaat tgataaagtc
     2401 ctaggcttag agttaggcgc cgatgattac gtgaccaagc cattttccaa ccgagaatta
     2461 gttgcacgtg tcaaagcaaa tcttcgtcgc ggtgccacgg ctgcgaagga accagaagag
     2521 gcagcacctg cggaattgac gattggtgat ttgacgatcc atccagaagc ttacatggtg
     2581 acgaaacgag gagaaacaat cgagttaaca catcgtgaat tcgaactact cttttacttg
     2641 gcgaagcacc ttggacaagt gatgacaaga gaacatttat tacaaacggt ttggggttat
     2701 gattattttg gagatgtacg aacagtggat gtaactgtac gtcgtttgcg tgaaaagatc
     2761 gaagataatc caagccatcc aaattattta gtgacacgtc gtggtgtcgg ttactatttg
     2821 cgtaacccag aacaggagta attggatgaa aagaaaagtc cgcttttttc gatcagtcaa
     2881 ttttaagatc gctattacct ttattctgat tttattgatc tcgatcgaaa ttattggtgc
     2941 ctactttata cgtggtttag aacgttccac gatcaataca tttattaaag atatgaatca
     3001 aacggtggaa tcattagcaa caacaatcag cccggaattg aatcgaaaag ataatgcaga
     3061 tgatgaagag gtaaatgcga atatcaaaag atttattgaa aacagtgcga ctagcgatat
     3121 catcgaaata cgggtcgttg acgaaaaagg gatcatccga ggaacaaccg atgtcaatga
     3181 acaaagcgct gtgggaaaga aaaatgatta tgttgatatc aatgatttca cgactaaacg
     3241 ttatgttgct ttagataacg acgataaacg ggtgaatatc aatgttcaac cgatcctgtc
     3301 cccgaccggc gatgccgtta tcggggctct ttacgtcaaa agtaatatcg aacaaaaata
     3361 ttcggaaatc aataacacag cagtcatttt ctttactgcc tcactaattg cggcatttat
     3421 ttcaatgatc gtatctgttt tagttgctcg ttcgattaca cagccgatcg gtgaaatgag
     3481 agaacaagcc attcgaatcg ctagaggaga ctacagtcgg aaagtcaaag tgcatggaca
     3541 agatgaactt ggacagctgg ctgatacctt caatcagtta gctgaacgta ttgaagaagc
     3601 tcaagataca atggaagctg aacgcaatcg tttggatagc gtgctatccc atatgacaga
     3661 cggcgtcatt gcgacagatc gcaggggtaa agtcattacg atcaatgata tggctgtttc
     3721 cttgctagat atcaaaaacg aggaagcaat cggacaatcg attttgacac ttttagatat
     3781 cgaagaagaa tatacgttgc ggaaattatt agaagatcca aacgaaatgg tacttgaccg
     3841 ttcaaccagt acattggaaa gtgatcagat gatcttgcga gtagactttt ctatgatccg
     3901 tcgcgaatca ggttttatca gcggattagt agctgtcttg catgatgtga cagaacaaga
     3961 aaaaacagaa cgggaacgtc gtgaattcgt ctctaatgtt tcccatgaac ttcgtacacc
     4021 gttgacaagt atgcgtagtt atatcgaagc attgagcgaa ggtgcgtgga aagacgagga
     4081 agtagcacca aattttttga aggtaacgct agatgaaaca gaccgaatga ttcgaatgat
     4141 caatgacctc ttaaatctat ctcgcatgga tacaggtaat acccagcttc aattagaata
     4201 tgtcaatttc aacgagttag tgaattttgt tcttgaccgg tttgatatga tggtgggaaa
     4261 tcaggaaaaa aattataaga tccgtcgtga atttacgcaa agagatcttt gggtcgaagt
     4321 agatacagat aaaatcatcc aagtagtcga taatatcatg aataacgcga tcaagtattc
     4381 accagatggg ggaacgatta cttgtcgctt attagaaacg cataataacg tggttttaag
     4441 tatcaccgat caaggattgg ggattcctaa aaaagatctg aaccgagtgt tcgagcggtt
     4501 ctatcgagta gataaagcac gtgcaagagc acaaggtggg acaggacttg gattagctat
     4561 ttctagagaa gtgattaagg cgcatcgagg cgctatttgg gcagagagca aggaaggaaa
     4621 agggtcgact ttttatatct cgctgccata tgaaccttat gaggaggaat ggtgggaatg
     4681 agaatctctg aaaaagtcgt tcgtatagga ctcattttga tggttgcgtt aagcatatac
     4741 ttctcttatg caatctggct gagcccagca ggaaaaagtt caatcaacgt agatgagaca
     4801 aacactcaaa tgatcgagtc tcaaagcaat cgaaaaactt ccgaagtctt tcttccgctt
     4861 catgttacat ggcaccattc gggaatgatc caagaaacca acagtgaaaa tctcgtgtac
     4921 cgattgcaat tgatcatcga taaagcaaga tttggaaagc tttctgaagt agtttcagga
     4981 gacaaatcac agtttgaaca ggtgaaaaat ctgaactctg gttttgagtt ggcctataat
     5041 gcgccttttt tgctaagaga atacaaggaa gcatttgatt tagatttaga tgtgtcgaac
     5101 ttggcaaaag aaagcgaaaa tatgtatttt actagaatac aattcgatca aggaaataaa
     5161 aaaatccgat ttttgaatta ttcgaaccat ctcgtatatg aagcaaatat ttcgttgaat
     5221 tggacagata tcaataaaga attaacagca aaagacacaa aatggacaga aatgacaaca
     5281 gaaccatcga cgatcgacac gcaatatgct acgaaacatt cgatcaaact gaaaaagtat
     5341 agttatatcc tgtcacagca accctataca ctttttagaa atgctttttt ccagaaacca
     5401 gatagcgtga aaaataatga tgaaagcaat gaattgattt tttacggtgg gaatgaaaca
     5461 atgtctatcc attcggaaac gcaagtagtt gattttcgtg gagagctgcc agagaaaaaa
     5521 gaaaatgcta gtgtattttc tgaaagtttc ccctatatta gcaaattagg cagttcttta
     5581 gggaacctca gatattttga ccgcagtgac aatacgatcg attatcggat attcgtggaa
     5641 ggcttcccgg tttttgggac agacagcaga ggacagattg gtgtggaagt tggcggtgaa
     5701 acgaatggtt ctgtgcaagt gaatatccaa accagtttga atacgattca agtgccgata
     5761 ccttcagacg aagaagtaga acttgcaagt acgaatgaaa tcatccagca gttaaaagct
     5821 aagggagcag atagcaacaa gattggttca gtgatcgttg gctatacatg gcaaaatgtc
     5881 aaagaaacga atcgtgtcgt tgatctctta cctgaatggt atgtgaaata taaagataac
     5941 tggtattcag ctaacgacct tctggaaaaa ttacctggat tggaggcgaa ttaattggat
     6001 ttcaaaaaaa tcgaatggat atttttcgtc gcttttttag ggttgaatgt gtttttattc
     6061 agcagttatc atgacgcggt ataccaagaa aacaatgtca ttcgctctaa tcagactgaa
     6121 tcaatccaac aacgtctggc tagcgacgat atcacttaca cggggaagat ttcgtctgag
     6181 aacaagcaag gctattatct tagcgcggag cagaccaatc ttagcacttc attagcgaat
     6241 tatcgcaagg ctggtaaaag cggcttgctg gcaagtggtg tgtttttaga cggtgatgtt
     6301 ttgacgaaat ctttatccag ttcagatgct gaaaagaacg tgatcgatcc agataaaatt
     6361 agtagttcct tggaagattt tttatctaac aaagacaata ttttattcgg taatgattat
     6421 gtgtacacga aaaacttttc tcatttagaa gaagaaccac tagaaatcca agcaagccaa
     6481 gagtatgaag gcatcccatt caatgatgat acagcaaaaa tcgttctttc tttagaaaaa
     6541 aacgataatg attatagcat cacgaaatac atgcagacgc atttatctga tatcgagcag
     6601 ctgcgcgaaa agacggaact gtatacggaa gaggaagcaa tcaatacatt gtacatcaat
     6661 aacaaaatac caagaggatc aaaaatttta tggcgtcagc tagcttattc ctgtattctg
     6721 aaagtccggg aaaaaaatgt gtatgttcct gtttggcatg tagcgatcga aacaagcgat
     6781 aaagtggtcc aaattgagag tgtcaacgct ttcagcaata cgatcgtgac aaacaatact
     6841 gtaccaaaag tggaagatca ataaaaaagc gagtataatg aaaaaagttt acaaagtaag
     6901 aagggaagta ggagtcaaat ggctgaagaa aaaccagctt ttaaaatcag tatcctagca
     6961 agtggaagtt cgggtaattc actttatatc gaaagtgaaa aaaaacggct tttggtcgat
     7021 gcaggactta gcggtaaaaa aatcacttcc ttgatggctc aaattgatcg gacaccggac
     7081 caattagatg gaatacttgt gacgcatgaa catcgagatc atatacatgg cgtgggtgtc
     7141 ttggctcgta agtatcattt ggatgttttt gccaatcagc agacttggga agcgatggaa
     7201 ccactgattg gaaatgtacc agtggaacaa aaacatctat ttgagatggg gaaagtcaga
     7261 acattcggcg atatcgatat tgagagtttc ggcgtctccc atgacgcagc ggctccgcaa
     7321 ttttatcgtt tccataaaga aaatcggtca ttcgtcatgt tgacggacac cggatattgc
     7381 agtgattata tgcgaggtgt cattgaaaat gccgatggtt atttgatgga aagtaatcat
     7441 gatcttgaga tgttacgcat gggaccttat ccgtggaatt taaaacagcg tattttagga
     7501 gatagaggac atctttccaa cgaagacggt gcacttgtca tgactgatgt gatcggtaat
     7561 cggaccaaac gaatctatct tggccatctt agcaaggaaa acaatatgaa agaacttgct
     7621 catttaacaa tggaaaatgt tttgaaagaa aaagattttg gcgttggaca tgattttgaa
     7681 atctatgata cagatccaga tgaagcaact gagctatttt cgatttaaac agttcaatca
     7741 ataaaaatat aaaaagcaga agataaaatc aatcagggtt ggttttatct tctattttta
     7801 tttttttagc atattaaaaa aataaccgta ttatcgactg actacactga tgtgctgctt
     7861 ttcatgtttc tcatccagta tctcatctac taatgcaatc gcgtaatctg ccatgctgat
     7921 cgtactgtcg ccagcagcgt ttctttgtaa ataatcatca cttaacaaat aagtacctgt
     7981 acgtttgcca tgtggatcaa ataaagaagc tggactgata taagtccaat gtagattttt
     8041 agattgtttc aattttaaca atccttcgta catattgaaa gctgttggat agaagggtgc
     8101 atttttaggt acttggtcaa tcatacgagt cgtcttttct gtatctaaga ataacgaaga
     8161 ggcaccccca acgacaatta agcgtgtatc ggttccttca agcatctcaa tcaaatggga
     8221 caaagaagtt tgatgcattt cttcttttcc tttgggagcg ttgaaagcat caacgacaac
     8281 atcaaaagat gcaagatcag tagttgtcaa ctcaaataaa tccttttgta taaacggaac
     8341 atctgatggc aatttttctg gatgacgcac gattgccgtc acgtctaaat ctctggacaa
     8401 tgcttcgtct aaaataaatg aacctgcatg gccagtagct ccaatgagtg caattttcat
     8461 aaaaaacctc cttttttatt cctgtccatt gtaagcagtt gctgaatatt cgtcaaagaa
     8521 tccgattttt gaaaagctca gtgcgcattc ctttcatggt tcgtgatcat tgggtatagt
     8581 taaattaaga aaactgattg ataaaaatag aagttgaagg agataagaaa tgaaagagtg
     8641 gttagatcgt gcctttttac caatgataac atctgttgtg aatcttagac ccttaactgc
     8701 tttgcgtaat ggaatgactt acacgatccc aataattatt gttggctcgc tgtttttctt
     8761 atttgctcat tttcctgtgg attacatcgc tcagtggata gacaaaacag gattttctat
     8821 gtattttaca caagtatacc aggctacatt tgatgtgata gccttttgga tcgtttttgc
     8881 cattgcatac gcttatgcaa aagaagaaga catcgatcgc ttaccagtcg gcataacagc
     8941 cttgtctgct tatctactgc ttattcagcc actaaatact cagatagata ctgtctggac
     9001 aggtgctgaa gggatactag gagcagttac aactgggctc atcatcggat ggggctatgc
     9061 acgtttagta agacttgcga aagggtggaa gcaaagagag aagatacctg aaaatgtttg
     9121 gcagtctttt acttcattga ttccaatcat tgttatagtc acttttacgc ttatcggttc
     9181 agcggttttt caacagttgt tcagaatgac tgttgttcaa ggagtatgga catatgtcca
     9241 gcttcccatt caatcgttca tagacacgtt gtttggtgtg cttttattag gtttttttgt
     9301 tccgttttta tggttatttg gtcttcatgg atctgcgatg gtcaatgggt tggttagtcc
     9361 cgtcttgcaa gcgaattcat tagcgaatgc agaaatctta gcctcaggac aagagttgac
     9421 ggtggcaaat ggcggacata tcgttactca gcaatttctc gatcagttca tgacggttac
     9481 gggtgctgga ttgacgttag gggctgtatt ttttatgacg gtttttgcga aatcgaagaa
     9541 atacagagaa ttaggaaatc ttgctctttt accagccttt ttcaacatca atgaatcaat
     9601 tattttttcc acaccgatcg tgatgaaccc gatgatggct gttcctttta ttttcgcacc
     9661 ggtcgtttca ggattgatta cctattccgc tttatatttt ggattcgttc ctttatttac
     9721 agcagtccaa gtcccttgga caacaccgcc gatcctctcg ggtttcttag taggcggagt
     9781 gcctgcagcg attttacaag gtatcgtgtt gtcaattagt tttttcattt atttcccatt
     9841 tttgaaaaaa atagattctg caaactgcaa aaaggaaaga cagacaaaaa atgatggagc
     9901 agcagaaaag atgaacgact aaaaaacaaa aatactcctg tcgctttaga ttgggaaaat
     9961 caccaatcta ggatgacagg agtatttata gtcatgttta tactagccct ttttggacag
    10021 ctaattgaac aagaacaact aatgtgttca ttcctacgtg tgtgatcatc gatgtccaga
    10081 tccgaccagt tgctttgtac tctaggctga agaagaaacc taggaaaaag tagattagca
    10141 gatgaccatc attatgagca aacgcaaaca gcaaagagct gatcactgct ccgacccaaa
    10201 aatttgaata tcgactgatg atccccagta tactgcggcg gaatacgaac tcttccatga
    10261 tgggtccagc aacagttgtc gccaaaataa aagcgggtgc ttccatgatc atctggatga
    10321 tattttgtgt attctcggaa ggggttgctt tgccaaacaa tacagattct aacatgacag
    10381 cgatgctttg cagaatcaat gcgacaaaga ttccaaccaa tccataaata acaatctttg
    10441 gagcagaagc tttttttacc gctgattcga tcgctaaggg ttcacgttgc ttaaaataaa
    10501 aaatagctag gacaacggcg cctagtatat acatgactgc agttgctgtg atcaattcag
    10561 acgtagattt tacaagtcct atcgaagcta ggatcaaggg tgagataaaa attagaccat
    10621 agcaaaaaat gctgaggaag ctatattttt ttaaagacat gtaattcctc cttttaaggg
    10681 ataacaagca tgcaaggcaa gcttatatcg attgatttca attatatcat aatttcaata
    10741 agcagctgtc agaataaaat ttcttttctt tgatttaaaa gcttgcaaaa aagagggaga
    10801 atgagtatta ttaaaaatgt aggttagcac tcgaaggtta agagtgctaa cagattaaaa
    10861 aaagagttat cggagggatt tatcgtgtta aaaccattag gtgatcgcgt cattatcgaa
    10921 gtcgcaaaag aagaagaaaa aactgtcgga ggaatcgttt tagcttctgc tgctaaagag
    10981 aaaccccaaa ctgggacagt tgttgcagtc ggtgaaggcc gtttgttaga aaacggtgaa
    11041 aaagttcctg ccgctgtaaa agcaggcgac caagttatgt tcgaaaaata cgccggtaca
    11101 gaagtaaaat acgaaggaaa agaatatctg atcgtcgcag gaaaagatat catggcgatt
    11161 gttgagtaaa tttggaagat aaaaaaataa tcaaaaataa tcaatgaggt gaatcaatca
    11221 tggcaaaaga attgaaattt gcagaagacg cacgcgcagc tatgttacgc ggggtagata
    11281 aattagcaga tacagtgaaa gtaacattag gacctaaagg ccgaaatgtc gtactagaaa
    11341 aatcttacgg ctctccattg atcacaaatg atggtgtgac gatcgcaaaa gaaatcgaat
    11401 tagaagatca ttttgaaaac atgggtgcaa aacttgtatc agaagtagca tcaaaaacaa
    11461 atgatattgc aggagacggt acaacgacag caactgttct gacacaagca atcgttcgcg
    11521 aaggtttaaa aaacgtaact gcaggtgcta atcctctagg cattcgtcgc gggatcgaat
    11581 tggcaacaaa agcagcagtc gaagaattgc ataatatctc aactgttgtt gattcaaaag
    11641 aagccattgc acaagtagca gctgtttctt cgggttctga taaagttgga catttgattg
    11701 ctgatgcaat ggaaaaagtt ggaaacgacg gtgtcatcac aatcgaagaa tcaaaaggga
    11761 tcgaaacaga actagatgtt gtagaaggta tgcagtttga tcgtggttac ttatcacaat
    11821 atatggtaac agataacgac aaaatggaag ctgttctaga aaacccatat atcttgatca
    11881 cagacaaaaa aatctctaac atccaagata ttctgccatt gttagaacaa atcttgcaac
    11941 aatcacgtcc attgttgatt attgctgacg atgtagatgg tgaagcattg ccaactcttg
    12001 tattgaacaa aatccgtgga acattcaacg tagtagctgt aaaagctcct ggtttcggcg
    12061 atcgtcgtaa agcaatgctt gaagatatcg ctattttgac aggtggtaca gtaattactg
    12121 acgatctagg tttagaattg aaagatgtaa caatcgaaaa cttaggaaat gcttctaaag
    12181 ttgttgtaga taaagacaat acaacgatcg tagaaggttc tggagaaaaa gaagcaatcg
    12241 aagctcgtgt gcaattgatc aaaaaccaaa ttgctgaaac aacttctgat tttgaccgcg
    12301 aaaaattaca agaacgctta gctaaattag caggtggtgt agctgttgtt aaagttggtg
    12361 cagctactga aacagaattg aaagaattaa aattacgcat tgaagatgca ttgaatgcta
    12421 cacgtgccgc agtagaagaa ggaatggtct caggtggtgg tacagctcta gtgaacgtta
    12481 tcagcaaagt ttctgctgta gaagcagaag gagacgtggc aacaggtatc aagatcgttg
    12541 ttcgtgcttt agaagaacca attcgtcaaa tcgctgaaaa cgctggttat gaaggatcag
    12601 tgattgttga taaattgaag aacgtggaac taggcactgg tttcaatgct gctactggag
    12661 aatgggtaaa catggttgaa gcaggtatcg tagacccaac taaagtaaca cgttctgcct
    12721 tgcaaaatgc cgcttccgtt tctgccttgt tattaacgac agaagcagtc gttgcagata
    12781 aaccagaacc agcagcgcca gcagctcctg caatggatcc atcaatgatg ggcggtatga
    12841 tgtaagaaaa agcaacttgc ttatctacaa ctgatcatta gtgaaagaca gataaaaaga
    12901 ggctggaaca gaagcgttta actccaagaa ataagaagaa attcacggaa attgcttttc
    12961 aaatttttgt gaatttcagc ttatttccga aggagttgct tctgcttccg ctgtttatac
    13021 gtgtttagag cgtgagacaa aagtgttctt tacttttgtc ccacgctctt ttttgtgtgt
    13081 aattataatg aaaatagtta tttttaatag ttataatatt ttatctatta aaagtaaata
    13141 tccatt
//
LOCUS       DAFENC010000059        12762 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.061, whole genome shotgun sequence.
ACCESSION   DAFENC010000059
VERSION     DAFENC010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12762
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.061"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(161..2158)
                     /gene="tkt"
                     /locus_tag="LP493_002432"
     CDS             complement(161..2158)
                     /gene="tkt"
                     /locus_tag="LP493_002432"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBL2134545.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2260..2511)
                     /locus_tag="LP493_002433"
     CDS             complement(2260..2511)
                     /locus_tag="LP493_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HBL2134546.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2658..3281
                     /gene="lexA"
                     /locus_tag="LP493_002434"
     CDS             2658..3281
                     /gene="lexA"
                     /locus_tag="LP493_002434"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HBL2134547.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3461..3679
                     /locus_tag="LP493_002435"
     CDS             3461..3679
                     /locus_tag="LP493_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134548.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3968..4480)
                     /locus_tag="LP493_002436"
     CDS             complement(3968..4480)
                     /locus_tag="LP493_002436"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBL2134549.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4494..6791)
                     /gene="recJ"
                     /locus_tag="LP493_002437"
     CDS             complement(4494..6791)
                     /gene="recJ"
                     /locus_tag="LP493_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HBL2134550.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6933..7376)
                     /locus_tag="LP493_002438"
     CDS             complement(6933..7376)
                     /locus_tag="LP493_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HBL2134551.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7377..8165)
                     /locus_tag="LP493_002439"
     CDS             complement(7377..8165)
                     /locus_tag="LP493_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL2134552.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8162..9103)
                     /locus_tag="LP493_002440"
     CDS             complement(8162..9103)
                     /locus_tag="LP493_002440"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HBL2134553.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9280..9867)
                     /locus_tag="LP493_002441"
     CDS             complement(9280..9867)
                     /locus_tag="LP493_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HBL2134554.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10088..11395)
                     /gene="obgE"
                     /locus_tag="LP493_002442"
     CDS             complement(10088..11395)
                     /gene="obgE"
                     /locus_tag="LP493_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HBL2134555.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11689..12699
                     /gene="gap"
                     /locus_tag="LP493_002443"
     CDS             11689..12699
                     /gene="gap"
                     /locus_tag="LP493_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBL2134556.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
BASE COUNT         3528 a         2858 c         2269 g         4107 t
ORIGIN      
        1 tcaagaaaca caaactaatc cgaagaattc tttgttttgt catttaaatg taacatagcc
       61 gaaaacgaaa agtaatattg atttattctt ctaacacata aagaacagct gtctccaact
      121 tgcagacagc tgttcttatc agtcaaacaa ttgcttggat ctatgatagt tgattgtacg
      181 tattcacgac attttctact gtaaatccaa attcttctaa aattttagtg ccaggggcag
      241 atgcaccgaa atgatcgatt gtaatcgttg cgccctctgt tcctacgtag cgttcccatc
      301 caaatgatgc agcagcttcg atagccacac gtttcttcac tgatttagga agtacacttt
      361 ctttatattc agaagattgt ttttcaaaga ggtcaaagct tggcatagaa acaacagaaa
      421 catctttgcc tttttcagcc aattcttttt gagctttcac agccaaatca acttcagaac
      481 ctgttgcaat caaaatacct tctggtgttt ctccttgtga tggagaaaga acatacgcgc
      541 cttttttcac catttcatct gctacttctt ttgtagaagg caatactgga aggttttgac
      601 gactcaatac aaggatagta ggcgcatctg ttgtctccat cgctactttc caagcagcac
      661 gtgtttcatt tccgtctgcc ggacgaatca cttgaacacc aggcatgcag cgaacagatg
      721 ctagttgttc aatcggttcg tgcgttggtc cgtcttctcc gacagcaacc gagtcatgtg
      781 ttaagacgta aacaacagga gtatgttgga ttgctgctaa acgaactgct ggtcttagat
      841 aatcgacaaa gacaaagaat gttccaccgt agatacgagt tccgccatga agttggatac
      901 cattcatagc cgaagccatt gcaaattcgc ggacaccgaa ccagatgttg cgtccttcat
      961 aatgttcagg agtgaaatct ttatctgcag ccaccattgt attattggaa cctgacaagt
     1021 ccgctgaacc accccagaag cttggtatag ctttcgataa ttcttggatg acttctttac
     1081 ttgaaacacg gcttgcttga ctgcttccaa cttcataagt tggcaattct gcatcccagt
     1141 tttctggtag tttgccatca aaagcatctt caaattgttg tgctaattca ggataagctt
     1201 ttttataatt ggcaaacatt tcattccatg catcttcagc tttttgtcct tcttctatca
     1261 tcgtttgatg gaagcgggca gctacttctt ctggaacagt gaaatctgga tactcccaac
     1321 cataaacttc tttagccatc ttgatgccat cttcaccaag aggagcacca tgaacagcag
     1381 atgttccttc tttaggagca ccatagccga tgactgtttt tacttcgatc aatgttggtt
     1441 tgtctgtttc agcttttgct tcttcaatcg ctttagagat tgcttctagg tcatttccgt
     1501 ctttcactaa gatatgttgc cagccatatg cttcatagcg agcaccaacg ttttctgtga
     1561 aagcttttga agttggaccg tctagtgaaa tatcgtttga atcgtataaa acgatcaatt
     1621 tccctagttt catatgacct gccatcgaac ttgcttcttg agatacccct tccatcaagt
     1681 ctccgtcacc gcatattgca tacgtatagt gatccatcac attaaagttt tctttgttat
     1741 acgttgctgc aaggtgcgct tctgccattg ccataccgac agccattgca atcccttgtc
     1801 ctaatggccc tgtagtggct tctacaccat ctgtatgatg tacttcagga tgtcctggtg
     1861 ttttagaatc ccattgacgg aattgtttca aatcatcgat tgtcacttga tagccagcta
     1921 aatgaagcaa gctatacaac attgctgacc catgtcctgc cgaaagaacg aaacggtcgc
     1981 ggtcagccca gttttttgat gtcgttggat ttactttcag gtgttttgtc cataacgcat
     2041 atgccatagg tgctgcgccc atcggcaatc caggatgtcc tgagtttgct ttttggactg
     2101 cttcaatact taatgtacga attgtgttaa cgccaagttg gtcaattttg tcaaacaaaa
     2161 taacccctcc tattaattta ggtttttttt acctttattt cttacacttt cattctataa
     2221 gatgtcacac gaaaaagcaa tctttttcag tattttttac taaaagttgt catttcggtt
     2281 gtgtaagcct tttttctttt ggatttcttt taatttttcc ggggtcacgt cattgccctc
     2341 aggatcgacg actttcattc cttcgatatg atgacgcata ccggaacgaa aagcttccaa
     2401 atactctttg cgcaagttga tttgttcttg ttcttcggct tttgagagac cattttcctt
     2461 ctttttacgt gcaagttcat tgatccgctc tattttttca ggtgacagca tgctcagccc
     2521 tccttttact ctccttcata ttatataaaa actgaaaaaa aaacaactag ataaactaaa
     2581 taaaatacga acattcgttt gatttagcgc tttttatatg gtactattta tttatcaagt
     2641 gaaagaaggt gtaccttgtg gcccgacaaa ctgaatcaag acaaatcgaa gtcttacgat
     2701 atatccatga acaagtaacc caaaaaggat acccgccgac tgtccgtgaa atcggggaag
     2761 ctgttcagct ttcttctact tctactgttc acggtcatct tgcacggctt gaaaaaaaag
     2821 ggtttatcca aagagatccg acgaaacctc gtgcaatcga gttgacaaaa caaggtttag
     2881 aaaagattgg gattcgtcca acaactattc cagtacttgg cgtcgtaaca gctggagaac
     2941 ccattttagc agtagaggat gcttcagact tctttccaat ccctcctaat ctttcttccg
     3001 aagaaggcag tctctttatg ctgacaattc gtggagatag tatgatcaat gctgggatat
     3061 tggatggtga caacgtgatc gttcggaagc aagaaactgc tcaaaatggc gatattgtca
     3121 ttgcaatgac tgccgaggac gaagcgactt gcaaacgatt ctataaagaa aaaaactttt
     3181 tccgtctgca gcctgaaaac gacttgctcg aaccaatcat cttagatcaa gtatctatat
     3241 taggacgagt agtaggactt tatcgtagtc atatctatta attgctacta attaaaagaa
     3301 aactttttaa aaagagtttg agacgttggt ctcaaactct tttttcgccc gggttcttct
     3361 tctttcaaat ttttatcact tccctcttta caaaccgaac aaatattcgt atactaaata
     3421 tacgaacaat tgttcgcata aattaaagag gtgagaattc atgaaatcaa tgagacgtct
     3481 tggcttagta ttaactgttt tgtttttagg tattattatt ggtaatttcg gcatacgtcc
     3541 agctttactt gtgtttgttc cgttatttac tttgtggttc atgttgtggg atgaaaagaa
     3601 gtaccgtcaa tctgagcggc gcagaattca tgaagatcat ttctatcatg agccctacta
     3661 cagatccagg caatcataat aaggattgac tgctaattat tcaaaagaca agaagttaaa
     3721 cttttacggg ggtgtgacaa aaatcggtca catccttttt ttcgaataaa cggtgttcta
     3781 aagccagttt ttcggtatta agtcaaattg cggaaaaagt gattttttaa acttctactg
     3841 gtctttgctt gtttccattt ataaaaaaat agcgaccctc aaaagtcaga tagagaatct
     3901 gacttttgag ggtcgcttta aaatcgcttc tttaagaata acatcaagaa tagcttcttt
     3961 tttctgctta atattccatt aatgtaatga tgtcatatcc tttgattttg tcgcgtccat
     4021 ggagatccat caattcgatc aaaaatgcgc agcctacgac tacaccgcct aattgttcga
     4081 tcagttcgat cgtcgctttg attgttcctc cagtagctag caaatcgtca caaatcagca
     4141 cacgttgacc tggtttaatg gcatccttat gcaatgtcaa tgtatctgtt ccatattcta
     4201 atccataagt cacttcgatg gtttctcgag gtaacttccc ttttttgcgg actggggcaa
     4261 aaccgactcc taactcataa gcaacaggac atcctacgat gaatccacgg gcttctggcc
     4321 caactaccat atcaattcgt ttttcttttg cataatttac gatttgttta gtagcttccc
     4381 gataagcgtc accatctgcc atcagtgggg aaatatctcg aaacacaatt ccttttgacg
     4441 gatagtcggg aatactggca atataatctt ttaaatccac tctttgtttc ctcctaggtt
     4501 gttaaccatt tctttatggt aggaatatcg ctcaaaagca aaaattcctc aactttgatt
     4561 ttattgagcc gtcgctggta taatctgctc tcagtcaaag gatgactttc tgggctagcg
     4621 actttttgta aaacaccgtt ctctattgta acaaatttca attcaaaaaa cacctgtatc
     4681 ataaaaatta ataatttttc agggatacgc aaatattgag ctattgcttt tattttatga
     4741 cgtatatcaa ttcgttcttg agaatggatc aatttaaaca attttgcgta ctgttctctt
     4801 gtgcctaccc cattcaaata ggcctcatca ggtgaaatcc ccatcagata aacacgattg
     4861 aatgaataag accgaaaaac ttctttcaga tccgctaaat catctggaca atccataaca
     4921 actagagagt ttggttttct tttttcaatt attgccttta cagaatctag tccttcgaaa
     4981 acaatcgcag cttcctggat aatctcaggc acgaatttca acgtcgaaga atcaaatgct
     5041 aaataaaggc taccttccga cgttcggctc tgttcacgga aacgttttgc ccgccaatca
     5101 aatacttgca gaccacccac agaaaaatca gataccatca gctgcggttt cttacgcccg
     5161 ttccattcat tgatcgaaag ctttcctacc acatctacct gattattcag cagttcttct
     5221 tcttgagtac caaaaccaaa agcgaccgca tcaagctgac tcgatgcatc ggaaaggaca
     5281 aatttcagat gctgttggtt tgctccgatt cttttgatat tttctgcttg gacttgtcga
     5341 aataaaaact gaggcaaagg attatccgta ccaaatggcg ccaatagttt cagctcatca
     5401 attcgctcta ctgttacttc atttggcagc aatacttcat caattctcaa ctcaggccct
     5461 ctcatcaagt caatttgatg atcgactata tattggttca tcttctcctg tagtatagtg
     5521 acattttcac ttggcatcgt taaaccgact gctgcatgat gtcctccgaa gtaagtaaat
     5581 aaatctcgca tctggtcaag catttcaaaa agattcaagg cttcaatact acgtccagat
     5641 cctttagctg atccatcttc ttttaaagta aggacaagcg ttggtttacc cgtttcattc
     5701 attattttcc cagcaacaat gcccaaaacg ccttcatgcc atcctcggtt taccaataga
     5761 tggatatgat tctccttatt gaccatcgct aatgcttctt gtgttatctg ctctacgatt
     5821 gcttttcttt cttcattgat ctcattcaat ttttttgctt gaacggatgc ttcctcttca
     5881 tcaaacgtcg caagtaacga gacggcagga cgtggatcgc ccatccgacc gattgcattt
     5941 agtctgggag caatcgaaaa accgatcgtt gtttcgtctg cgtccctcat ttttacgccg
     6001 ctttcttcaa atagcgcctg aagtcctatc cgttctgaat gatgaatggc atcgattcct
     6061 aatgaaacaa ggattcgatt ctcatcagtc aatgaaacta aatcggcgat cgttcctatc
     6121 gctactaaat ccaaaaattc tgcaggcggt tcttccaata atgcagaagc tactttgaat
     6181 gctactccga ctcctgccaa atctggaaat ggatagtgcc ccgctggatg acgagggtga
     6241 acaatcgcat aagcgtctgg taaattctca ggtagttcgt gatgatctgt aatgatcacg
     6301 tctacaccag cttgctgagc gtatgctacc gcatcatttc ctgctacccc gttatcaaca
     6361 gtgatgatca actggattcc ttcttcgatc ttttcttggt ataccgattg gtttggtcca
     6421 tacccatgct caaatcgatt tggcaggaat acttctactt ctgcaccaag taattccagt
     6481 gtttctttca ttaccgttgc actggtgatc ccatctgcgt cataatcacc gtaaacgagg
     6541 attttttctc cactgattac agcttcttgg attcggctga ttgctttatc catatcgtgt
     6601 atcagatacg gatcatgtaa ttcttgttcc tttggatgta aaaatcggtt gatatccttt
     6661 tcctcatggt aacctctttg ccacagtaac ttaccgacaa atggagataa tttcagttca
     6721 cggatcattt ggagaaagga ttcagaaggc tctgtctcgc ttaacttcca atcaaaattt
     6781 gcttgtctca ctttctcact cctaacttag ttattatagc aaaggaaatc agcaaaaaaa
     6841 agcagaaaga aagaataaaa acagatcaga tccgctagac agatgttcag caggacctga
     6901 tcttttgtac gaccatttat gaaatatccc tattagtcaa aataattgaa gctttgtttg
     6961 ggcgattgag ttttttgttc ttccggcgct ttcaattgac tgatttgtgc ggttttcgct
     7021 tgtaactccg cctgataagc agcttccaac tccgcacgtt cgtttctaaa ctcgcgttgc
     7081 tgttcttctt ttgcttcttc aattttcttt tgaagttctg tttgatattc tgacatttcc
     7141 tgagtcagct gtttgatttg ctttttttgc tgccatagtg ttgccgaagc agtcaaaaat
     7201 acaatcagtg caccaatcag cgcagaaccg atgatcacta agatcaatgg cgcagaaaag
     7261 gaagtgaagc caaaacttac aggaacattt ttattgttca atacagcaaa aagaacaata
     7321 atcaaaacta aaacaaatcc aagaatcaca ttgctttgct ttttcaattc cttcacctac
     7381 tttttgttaa aaattccgct ggctaaataa tcaccaatcg ttggaaacag cgtataaaat
     7441 tttgatgcaa cttctaaaat aaacggttga ttgatttccc gttttggatg tctcatattg
     7501 cggacgatca tttttgccaa cttggcaggt tctaaaacga tttgtccgac tttttccaaa
     7561 tagcttccgc ttggatcagc cttatcgaag aaatttgtct cgattggacc tggattcact
     7621 gtcgtaacag ctacgccaag tggtttcaat tctaatcgca aagcgttgga gaagccaagg
     7681 actgcaaatt tcgtggcaga ataaaccgtt gattttgcag ttgccatttt tccagccata
     7741 gaggcgatat taatgatatg accttgtctt ctttctgcca tatcgatcgc aaatttttgt
     7801 gtcaaaacca tcattcctaa gatgttgact tcaaacatat cgtatgcttt tccaaggtcg
     7861 aatgtaagga agtcttcgaa aatcccaaaa cccgcattgt ttaccagaat atcgacgcgc
     7921 ccgacttctt ccatcacctt ttcatataat tcgtccacgc tttcaggatt gctgacgtct
     7981 accttgaaag cataagcctc tttgccgctc aagcgtctgc actcgtctct gacaccttct
     8041 acaaatgcca ttcttcgtgc gcaacttata acgattgctc cttgctttgc tgcttcataa
     8101 cagatttgtg cgcccagacc gcctgaacta cctgttacta aaacaacttt atcttctaaa
     8161 ttcatgcctc ttcctcctcg cgaaatggaa tctcaatgct atcaaaatct ttcataatcg
     8221 tcgtgttttc aaacacttct tgtgcttctt tttcaagctc taaagctgct tttcctaaat
     8281 atctcgcact gatatgagta agtagcagcc gttttgcctg cgcttctttt gcaacttcag
     8341 cagcttgatg agtcgtggaa tggaaatagt tgtgcgccat tcttgcttca tctttattaa
     8401 atgtgctttc atgtaccaga atatcgctat tttccgcaag cacaacggaa ttatgtgttt
     8461 ttctcgtatc gcctaaaata gtcacgattc gtcctttttt atctggacct acgaaatctt
     8521 ttccattgat cgtccgccca tcttctagtt ggatcgtttc accttgcttc agtttgccgt
     8581 acagtggtcc agctggaata cctaattctt ttagacgatc cacctgcaat tctcctttat
     8641 gatcatgttc aaccacacga taaccaaaac tgtcgatccc atgatttagt ttttttgtat
     8701 aaacagaaaa ttgctgatca gtaaaaatcg gggctgtttc atttagctca atgaatttca
     8761 gcggataact taaacgcgtt tgcgaaatac ctaaagagac ttttatgtat tcctctatcc
     8821 cttttggccc gtaaatctct aatggcgtat ccccaccttg aaatgaccgg ctgctgatga
     8881 gcccgggaag tccaaaaata tgatcgccgt gtaaatgtgt aatgaaaatt ttaccgattt
     8941 ttctcggacg aatagtcgtt cgcaaaatct gcatttgcgt gccttcgcca cagtcgaaca
     9001 accaaacttc attgcgctcg tctaaaagtt tcaatgctat acttgtcaca tttctatgtt
     9061 ttgcaggaac acctgcacct gttcctaaaa attgtaattc cataatctac ctgactttct
     9121 ttaagttcct ctttaatttt agggtaaaaa gaagggataa tcaaccgtaa gtcgagaatg
     9181 ggttcaaatt aaaaataacg ttctaaagcg atagcgtttt ctttgaaaat tactataaaa
     9241 acagcagcga acccgtttga gatcctctgc tgttttttat taatttgaag atccagaact
     9301 ttcattgtcg ttggaagttt gcggatgttt gtccttccaa gtcttttgtg cagcttcttt
     9361 cgcatgattt tcagcttctt tcgcatcatg cacatctttt tcgacatctt cataatccaa
     9421 gcgagtaatt tctccgccta attccatcat taccaattga ttcagtgggc gattgtcctc
     9481 ttcatcagca atcaagatca gtcctgtagc tccttcaccg attttatttc ctacaaagtc
     9541 gaacacggtc tgggcatctt ttatttcttt ggcatcttgt gtcgcaccga tcattcctcc
     9601 ggcaaaccat cctaataaaa tccctagcgg accacctaat acaccaacca acattccgat
     9661 taatccaccc gtagaagatt tgttattacc ggtaaagtcg ataaaatctt ctattttgaa
     9721 ttgatgtgtc ccattaggat catggctgac aactgccatc tgttctcctt taatcgaacg
     9781 aacagcatgt aactttttga tttctgaaaa tgcctgatat gcctggcttt ctacttgaaa
     9841 atttaaaatg attactcgtt tgctcattaa aaacgcccct ttcatacctt cttgttattt
     9901 attttacctt taattgaaaa ataagaaaag aaaagcactc tttttttcca ataaaatagg
     9961 gctgtgacaa aagtcgtatc acagctcctt tttccgaata aacggcgttc ttgaagctga
    10021 tcacttctgt cacaacctcc cttaaatctg aatctatatt ttttggtatt tgtttttatt
    10081 tgcttgccta ttcgacaaat tcaaattcaa actcaccgat acgtacaagg tcgccatctt
    10141 tcgcaccgcg tgcccgaaga gcttcatcca cacccatacc acgtaattga cgagcaaaac
    10201 gcatcactgt ttcatcatga tcgaaattcg tcatttggaa taatttttcg atcttctcac
    10261 cagataagat ccacgttgca tctgaatcac gatcgatttg gaactcagga ccttctggat
    10321 tgaatccata gtgtacagtt tcttcttcca gttcttcttc gtacaatggg aattctggcg
    10381 ttacttctaa caaatctgct gtagcattca ataacgcgtc caatccttgt cgagtcactc
    10441 cagaaattgg aaatactggg atgtcatcag caaattcatc ttctttttcc ttgttcagct
    10501 gttctttgaa tttcactaga ttttccggtg catccggcat atccattttg tttgccacga
    10561 tgatttgcgg acgctctagc aagcgtaagt tataagtaga taattctttg ttgatggcaa
    10621 gatagtcttc ataaggatct cgtccttcca tcccactcat atcgatcaca tgtaaaatta
    10681 ctcgtgttct ttcgatatga cgaaggaatt gtgtacccag cccaacacct tgcgaagctc
    10741 cttcaatcaa gcctggcaag tctgctgcgg caaaacttct gccatcactt gtagtaacca
    10801 ttcctagatt aggtacgagc gtcgtgaaat gataagcgcc gatttttgga cgagcagatg
    10861 aaataacgga tagtaaagtc gatttcccga cagatggaaa acctacaagt ccaacgtctg
    10921 ccaatacttt caattctagt tcgatttttc gctcttgtcc tggttcaccg ttttcagcaa
    10981 tttccggtgc aggattccga ggagaggcaa aacggatatt ccctcgtcca ccgcgtccac
    11041 cttttgccac aactagtgtt tgaccatttt caattaaatc tcctaaaaga gcaccagtct
    11101 ccgcatctcg gacagtggtt ccttgtggta ctttaacata ggtatcttct gaaccacgac
    11161 cgtgcatccc tttactcatc ccattttcac ctggctgcgc tttgaaatgg cgattgaacc
    11221 gaaaatccat caatgtacgt aacccttcat cgacgatcaa gatgacatcg ccgccacgac
    11281 caccgtctcc gccagccggt ccgccgtcag gaacgtattt ttcgcgacga aatgcaacca
    11341 ttccgtctcc gcccttgcca gctttcacat cgatcgttac ttgatctaaa aacatggaca
    11401 taattaagtc ctcctattat tcatttattt atttgactgc ctgaatttcc acaataaaca
    11461 aaagtcttac ttattttatc ggtgaaatct gattttgtct atcatttcag caaaaagatt
    11521 gtttaccttc ttcttttttt atcatttggt aaggtttcca accttttttc tgctaccaag
    11581 tataattttt tgacaaaata ttctttgcgt agcagaataa cagtgtatta attgtattaa
    11641 ttgaggatgc cgtttcacag cacccctaat aaaggaggaa cttttgatat gacagtaaaa
    11701 gtaggtatta acggatttgg gcgtattggc cgtctggctt tccgccgcat caaagaagtc
    11761 tcagatgata ttgaagtagt agcaatcaac gacttaacaa gtccaactat gttagcacaa
    11821 ttattgcaat ttgactctac tcatggtact tatcctggca cagttactgc aacagaagac
    11881 tcaatcgtag tggatggcga agcaactcgt gtttatgcag aacccgacgc aagcaaaatc
    11941 ccttgggcaa aagaaaacgg tgtagatatc gtactagaat gtactggttt ttatacatct
    12001 gaagaaaaag caaaagcgca tttagatgct ggtgtcaaac gagtagttat ttctgcccca
    12061 gctggtgcta tgaaaaccat cgtctataac gtcaatgatg atacattaga tgaaaacgac
    12121 aaaatcatct cagcaggttc atgtacaaca aactgtttag cacctatggc ttatttctta
    12181 aataatgaat ttgggatcga agttggtaca atgacaacag ttcatgccta cacttccaca
    12241 caaatgctct tagatggacc tgtaaaaggc ggtaatttgc gtgctgctcg ttcagctgct
    12301 gacaatacta tcccacattc tactggtgct gcgaaagcaa tcggcttagt tatccctgag
    12361 ctacaaggaa aattacaagg acacgcacaa cgtgttccag tcgttgatgg ttcattaact
    12421 gaattggttt cagtattgaa aacaaaagta actgctgatc aagtaaacga agcaatcaaa
    12481 aaacacacag ttgacaatcc ttcattcggg tatgatgacc gtcaaatcgt ttctagcgat
    12541 gtcattggaa caactcaagg ttcgatcttt gacccaacgc aaacagaagt aacaactgct
    12601 ggtgatttcc aacttgttaa aactgttgca tggtatgaca atgagtatgg atttacttgc
    12661 caaatgattc gcttactaga aaaattcgct aacttgtaat ttgatagatc aatcgataaa
    12721 agaagccttt gactggatcc agtcaaaggc ttctttcttt tc
//
LOCUS       DAFENC010000060        12743 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.062, whole genome shotgun sequence.
ACCESSION   DAFENC010000060
VERSION     DAFENC010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12743
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.062"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            102..545
                     /locus_tag="LP493_002444"
     CDS             102..545
                     /locus_tag="LP493_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL2134557.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(551..1735)
                     /locus_tag="LP493_002445"
     CDS             complement(551..1735)
                     /locus_tag="LP493_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HBL2134558.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            2003..2701
                     /locus_tag="LP493_002446"
     CDS             2003..2701
                     /locus_tag="LP493_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBL2134559.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2708..3385
                     /gene="nth"
                     /locus_tag="LP493_002447"
     CDS             2708..3385
                     /gene="nth"
                     /locus_tag="LP493_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBL2134560.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(3511..4044)
                     /locus_tag="LP493_002448"
     CDS             complement(3511..4044)
                     /locus_tag="LP493_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134561.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(4341..6722)
                     /locus_tag="LP493_002449"
     CDS             complement(4341..6722)
                     /locus_tag="LP493_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBL2134562.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(6712..7359)
                     /gene="recU"
                     /locus_tag="LP493_002450"
     CDS             complement(6712..7359)
                     /gene="recU"
                     /locus_tag="LP493_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HBL2134563.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            7423..7962
                     /locus_tag="LP493_002451"
     CDS             7423..7962
                     /locus_tag="LP493_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HBL2134564.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            8052..8471
                     /gene="gpsB"
                     /locus_tag="LP493_002452"
     CDS             8052..8471
                     /gene="gpsB"
                     /locus_tag="LP493_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HBL2134565.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            8493..8860
                     /gene="rnpB"
                     /locus_tag="LP493_002453"
     ncRNA           8493..8860
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="LP493_002453"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9069..10235
                     /locus_tag="LP493_002454"
     CDS             9069..10235
                     /locus_tag="LP493_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HBL2134566.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            10281..11777
                     /locus_tag="LP493_002455"
     CDS             10281..11777
                     /locus_tag="LP493_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HBL2134567.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            11858..12541
                     /locus_tag="LP493_002456"
     CDS             11858..12541
                     /locus_tag="LP493_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBL2134568.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
BASE COUNT         4273 a         2230 c         2630 g         3610 t
ORIGIN      
        1 ttttttcttg gtttcagatt gggttttcct acaaaatatt tttatctttg ttgaatagga
       61 aacaaaaaaa caatataatg aaagaaaaag aaggtgtaga aatggataaa agacaactgc
      121 taatagaaga atatctggat ttagctaatg agattattca tcgtaataaa ccagaaatgg
      181 aaaaagaatt tgcaggattt actctaaatg aactagaagt gattgaacat atcgggaaaa
      241 tccctgatcc taacgtgaca aaattagcga atgctagtta catgactaga ggagccatca
      301 gtaagctaac aaaaaaactg atagctagag ggatcataaa cacttatcaa agcgaagaga
      361 ataaaaaaga aatctatttt caattgacgc caatcggaca aaaaataagg aatagacacg
      421 agcaactcca tcaaaaatgg gtacagcgag atgctactgt atttgaaaat atgtcaaaag
      481 aagaatttga cacagtattt cgttttatcg gtcgatacag agaatttata cgaagtagca
      541 aatgaagcta ctatttttta ttgtagtgat aataggcaaa aatcataagc aaaaatccga
      601 ataccgtcgg aagaaatggt gctgcagcat aaagctgtcc tgcgattagc gggccgatga
      661 cgcgcgatag agattgtata ctttgggtac cgcccattac aagaccttgc tggttatctg
      721 agacagaatt ggatagttgg ccattgaata caggagtaaa aatagaatca ccgaaaccat
      781 aacagataat cccaaataaa aacaaaatcg gcagtagaag aattccagat aatgtgatga
      841 atagataggc gaggatttca ctgaacatcc ctattcttgt gatctgctgt tctgaaaatt
      901 ttttgagcaa tcgaggcata atgaacaatt gcgagacagt atccaagatt ccaatcaaag
      961 agaagcttaa accaaccaac ccagccttcc actgaaaggc gtcaatcgaa aattgagaaa
     1021 agatagattg aagagagcca gctgccaacc aaacagcaaa acctgctgtc aataaaggaa
     1081 taacggatga aatcttgaat aattgttgta attggtgaaa aggtcttaca tgggagaaac
     1141 ttaaatctac tgaacgtttt tttattggaa ggctttctag cataaatgtg tagccataaa
     1201 cggcatttaa gaaagtaaag agtgctccaa taaatatagg aacagaattc cccaactcag
     1261 ctaatagacc ccctataata ggacccagcg ttgttcctat accgactaaa gcacccatcc
     1321 atccaaaaac tttggttctt tcattaggtt ccgtgatgtc ggcaaagtaa gcatataagg
     1381 tggagatttc tcctgccgtc aatccttcaa tgatacgacc aaggaacaac atccatatcg
     1441 aatttcctaa accaaaaagc aaatatccga tacttgatcc taataaactg ataataagga
     1501 tcggatgacg cccaaaatga tcacttaagc taccgagaat gggggcagat aagaaggcag
     1561 ctagagcata aacagacatg agcaaagtga tatagaaagc ttgctgatgt atggagtgag
     1621 aataaggcag cgttaaaaac ggaagtacag gactgacgat agtaaatcct aatccagtga
     1681 ataagacaga gacgtatcca aaaactttag aatgtttatt tgtgaaactg tacatgtaaa
     1741 aactccttta tgcaataatg ttaacttgga aacaaaaata gtgtatagta attttgtttc
     1801 cttgtcaaca ttctaaggaa cagcgaaatc tacttaattt atttattccg aaaagtgaag
     1861 atacgcatca aaaacatgaa caaacaaaaa tcaagtagac gacattgtaa atctgaccga
     1921 tcagtgaagt aaatagaaaa gaaacctgtt cttgcttccc atgttttttt tacgtatact
     1981 gtgattgagc ggaggagaaa tcatgttgaa tttagaaaat tacttaagcg ctggacaaac
     2041 agtcatatct aatcttttac ttaaaaatta tcataggatc ggtctacaat ctgaagaatt
     2101 tttatttgtt ctacagttgc atatggcaca gcttgaagga gatactttcc ctgatttgca
     2161 gatgattgct atggatatgg gaatcaaaca agatcagatt tttcaaatac tggatcgtct
     2221 cgtaacaaat ggatttatca agatagaaac gacgattgtc aacggtaaaa aagcagatcg
     2281 atataatctt taccccatct atgatctatt aggtgagtat ttaaaaacac aagaaaaaaa
     2341 atacgaagaa aaaacacaag aaaaagaaat ccagtcagtg tatcaattat ttgaacaaga
     2401 atttggacgc ccgctttctt cgatcgagtt ccagcggatc ggacaatggc tagaagaaga
     2461 ccattatcag ccggaaattt tgaagctagc actgcgggaa gccgtattaa atcaggctta
     2521 tagttttaat tacgttgacc gcattttgct atcgtgggaa agaaaaaatc tacgtacaaa
     2581 acaacaagtg gaagaagacc aaaaacgaag aaaacagcag cttcttcaaa gagaagtaga
     2641 acagtcagct caacaagaag aattgccgaa agtctcactg aaaaattggt tggaggagta
     2701 gcggaatatg ttaagcaaac aaaaaacaat ggaagctcta gaaacgatgt atggaatgtt
     2761 tcccgaagca catggagaac tcaagcacaa taatccattt gagttattga ttgcagtgat
     2821 cttaagtgcc caggcgacag atgtatcagt gaataaagca acgccagatt tgtttgcctc
     2881 ttttccgaca cccgatgcgt tagcagaagc ttcaatcgat gaaatcattc ttaaaataaa
     2941 aacgattggt ttgtatcgaa ataaagcaaa aaacatcaaa gcgtgtgcac agcagctgat
     3001 tgaacgtttc gatgggcaag tgccaacgtc aagagaagaa ttgatgtctc ttcctggtgt
     3061 aggcagaaag acagcaaatg tcgtattggg ggatgcattc gggataccag caatcgcagt
     3121 agatacccac gtggaacgtg tctcaaaacg cctgaggatc tgcaaactag atgctacggt
     3181 catggaagta gaagaaacac tgatgcggaa agtaccacaa gaattatggg taaagacaca
     3241 tcatacactg attttttttg gtagatatca ttgcacggca agaaatccca agtgcgaggt
     3301 atgtcctttg ctatcaatat gtcaagatgg gaaaaatcgg atgcgtctaa aagaaaaggc
     3361 gctaaaaaag aaaccacgcc tgtagacgtg gtttctttaa ttgcaaataa atgtatgaat
     3421 tatcttgtta ttatggagaa aagctgtttc gtttatcttt tttgcatgaa aaagtaaatg
     3481 tacatactca gtagctagga tggtaactta ttacaattta ttgcgataaa aataaaagtt
     3541 gttattttta ttgggaaaat acccgatgta gaaaataatg ccttccaata tacctataaa
     3601 ataagtccag tattccaaag gattatataa ataagtgacg tatctatcta aaggtgtaat
     3661 aaaaatgata agtgataata aaaaaatacc atttataact aaacataaac taatggattt
     3721 gggcggtttc aggctcatca gaaaaatata gattctggtg aacaacaacc ataaaaaagt
     3781 gagaatcatt gcatgagagc ttctttccat aaattttcct ttaagagtag tgcttaaaag
     3841 tacagaaaaa ataataaatg caaggatagg agcaattaaa gtaaatttat ttaataataa
     3901 acaaaatttt tcagcttttt tattcttgga ataacgaggt attgttttcg ataaaaaaag
     3961 atggtgcaga caaattatga taattaagca tactatcaga taactcaaaa tgaagccttc
     4021 tttcaaaaaa ttattcaaaa ccatatattg tattttttat ttgataataa caatgggatt
     4081 attaagaagt ggcactaaat aaaagactag tgtgtattta gccgatttaa ttataaacaa
     4141 gtaaatggat aaagtatatg taatgataaa agaaaaatgg attttctaat ttttaagcta
     4201 aatgttagat cacacatgta tatgctggat agtcttataa aaaatcatgt aatacagctt
     4261 ggtacatgat ttttatttgt agctgttttt tacatagaca caaaaaagaa accacgcttg
     4321 tagacgtggt ttctttttta ctatctgttt ccagaagctg aggtgctgct ggatggtgta
     4381 tggtcatttg cagcatccgc tccgctagtt gctggctcac tggaagaagc aggaggagca
     4441 gatgaagacg gtgtcgagct ttcttcggat gaagaagaag gaaccgttgt tgaagacgct
     4501 ggctcgcttg tttctgctgt cgtgctttct tttgaggact cagcagttga ttcgctttga
     4561 ctagtagagc tagagctttg agtcgttgtc tctgttgttg agcttccagg agtctggaca
     4621 tagctggaag atggaatagt tgttgatggt gtaattgcat tcgatctagc tgtatattga
     4681 tctttgtagt acagttcacc gcccacacga attaatccgc ttggcatctc ccagtctgta
     4741 tttgtcacgt tagctgaaac atactgcata agctcgcgat aaacatcaga ggctacgtgt
     4801 gacgattctg aagtgacagg cgtcattttt ttattgtaac ctgtccacac ggaaatcgaa
     4861 taatttggcg tatagcccgc aaataggata tctggataca ccccagaaga aataccaagt
     4921 tttgcatact cgtcatctgt gtaattggat gttccggtct taccggcttg atataaccca
     4981 gcgatttgcg cattcgtacc agttccttca gtgatcgtat cttttaaaat gtctgtgatc
     5041 atataagctg tttctggaga catggctgtt tttccatctg gctcataagt ttcttctgtt
     5101 ccgtcttgga agacgatttt attaacatat tgaggtttgt aataagtccc tccattggcg
     5161 aaagccgcat aggctgctgc catttttaag gaagaagctc cgtattttgt cccatcttgt
     5221 tcttccgtat tactagagat cgcattcgat tgatggatcg tactgtattc gatcccaaga
     5281 ttttttaaga aagaagccac tttatctgaa ccgacttcat tgaataattt gactgctgga
     5341 acattacggg ataagtaaag tgcttggcgt aaagtaatgg tgcccatata ttgattatcc
     5401 cagtttccta caggagtcga agtcccttca tagttatacg gtgcgtcagt aatagttttt
     5461 ccagtagaat atttcaaata ttcaaaagct ggtccgtaat ctgtgacagg tttcatcgta
     5521 gaaccaaaat cacgggaagt attcactgct aagttgttgc ctaaagttac gtcttctgcg
     5581 atgtgacgtc cgccaatctg ggcttttact ttcccggtat tggtgtcgat aagggtggag
     5641 gcaacttgca tctcgtcgtc tgggtaagag acatactgat ccgtgttgac gatatcatat
     5701 agtttctttt gggcgtccag atccaaattc gtataaatct ctaaaccgtc tgtgtagaca
     5761 ttcttatctg ttttttcttg tacttcattg atgacttctt tgacataatt atcgacgatc
     5821 ttagtattgt catcggattg agttagttct tgcagaccat ccgttaccgg tacattaaca
     5881 gcttgatcat attctgtttg agagattttt tcgttttgaa gcatcgtata caaaacagta
     5941 tctcgtcttt tcttcgcctg atctggataa acataaggat cataggcgga aggggcttga
     6001 ggcatcccag caagcaatgc tgtttgcggt aaagaaagtt ctgataattt cttaccaaag
     6061 tacatctcag aagctgtctc catcccgtac aagccgtttg acatatacac tttatttacg
     6121 tagtaggtca agatctcttg tttcgatttt ttttgttcca atcttacagc catccacgct
     6181 tcttgggcct tgcgtttcag agtctgatcc tcggcactgg tggagaagaa ggaaagtttg
     6241 atcaattgct gtgtcaaagt acttccgcct tgcagtccgc cagaggtaaa gttagagagg
     6301 gcagaaccga tgatccgaat agggtcaacc ccgatgtgtt tataaaaacg gcgatcttct
     6361 accgacacga tcgcatcttc taatgttttc ggtaattcat tcgcagaaat tttttcacgc
     6421 ttttctgcgc ctaaatcttc gaatagttcg ccatcttgtg tatatagttt ggaagatacg
     6481 gtagcgtcta attttttatc cgtcaattcg ggcgcatctt ttgcgtaata ccagaaaagt
     6541 cctacacctg ctaaaaagag gatacagaaa aatgagagta ttcctaaaag gatcttgata
     6601 aataatcctt ttttatgtgt tccagaggac tttccagaac ctttgccaga attcttcttc
     6661 acactctttt taggagtagg ctgtttctgt cgtctagagc ttctagtttg ttcatttgcc
     6721 attcttgctt tctccttcaa tagataatgt tgataaatag aagtcaaccg cgtccaaata
     6781 aggaatccgc ggagaaatac cagttttgat ctctattcct agttcttcga tcaaagataa
     6841 aggtagtgat ttgcgtcctt tttccttttg ggcgtcccag taagcaatca aatgaacact
     6901 attcaaataa aaacagcgct tcaaagacga aaaccataac aagacaaagc agaccccatt
     6961 ttgttcgagg catgctttca tatgttcgat ttgatgggca tggaagtttt taaagggaaa
     7021 agatgttttg ttcttggttt cttttgcttc aaagtccaag taaaagcctc gatagacgcc
     7081 attatagtct gtagttgagg cttgggtaaa gtaggcttcc ttgatcacag cagcacttct
     7141 cttaggatag tctactttca cgatttggat aggggtaggc tttttatgga taaccgccaa
     7201 cccgcgggaa agataatatt tattactttc attgattgct tcttcaaagc gcatcccccg
     7261 attgccgaat tcagtgatct gatttctttt ttcttgaatt ttttcgacgg gagaggcatt
     7321 cttataataa ggttggccat ttggatagcg caataccatc tttaatcaca ctcctaggcc
     7381 acattatagc aaaaaagcgg atagaaagaa aaggaatctg agatggataa gtcaaaagta
     7441 atctatgtgt ctgggtatcg aagtttcgaa ctcggtgttt ttaaagaaaa tgatcctaaa
     7501 atccaagttg ttaaaaatgt tttaaaaaaa gaactccatc agttagcaga agaagggctg
     7561 gaatgggtac ttgtcagtgg gaatttgggc gtcgaactat gggctgtgca aatagtagcg
     7621 gaattgaaag aagaatatcc ggaactatct cttggtattt tgtatccttt ttctgatttt
     7681 ggtaataact ggaatgaagg gaaccaagaa aaaaaacaat tagcagaaca attagcagat
     7741 tatgtcgaag ctgttagcca tcaaccctac caatcaccta gtcagctaaa gaatcacact
     7801 cgttttatac ttgagcatac agtgggctgt ctgctgatct atgatgaaga attccctgga
     7861 aaaacgaagt atttttttga agatgcacag aattaccaag cagatcatcc ctacgaaatt
     7921 cggctgatca gtatggacga tcttcaaaat tttagtgaat aatcgatatt gtgtttgatt
     7981 tatcaacttt tttcctatac aatgaaaaag gtagaaatgt tattacgtaa atgaaaacta
     8041 gaggtgtaaa tatggcgaat ttggtttata gtcctaaaga cattttacaa caagaattca
     8101 aaacaaaaat gcgcggctat gatcccgttg aagttgatga attcttagac aatatcatca
     8161 aagattatga aacttacagc aaagaactcc ttgctttaca agaagaaaac gatcgattga
     8221 gtgcaaaagt agctcaatta tctaaaactc aaggagcagc tcaaacacgc gtgcaacaaa
     8281 cagaggcacc aaagagcgca gcagtgacca attttgatat cttaaaacgc ttgtcaaatc
     8341 ttgaacgtga agtatttggt aaaaagcttg atcaacaagc aagtgcagtc aaaccagcac
     8401 aacctaatcc aaataactac acaaatgcag acacaagctt agatgataat gaaaaaacac
     8461 gtcaatttta atttttgatt aatgaatttg cggttttcgg gtaatcgcgg tctgacttga
     8521 tcaggctgag gaaagtccat gctcgcacag gctgtgatgc ctgtagtgtt cgtgcttagc
     8581 gaaaccataa gctaaggtac tctttggagt aacggcagga aaacaagcta aggcttcggc
     8641 tatgcttaag tatccttgaa agtgccacag tgacgaagcg gctggggaaa cccatccggt
     8701 ggaacgcggt aaacccctcg agcgagcaac ccaaacaatg gtaggggcgc tttttgtctg
     8761 gaagaagaac aggacaaaaa ggcagtataa ctgcagatag atggttaccg ctttgttttt
     8821 tctccctgga aaagcaaagt acagaacatg gcttatagaa aaccgcaaac atcagggaat
     8881 taggtcgtga caaaagtaat gcgttataag aaacaagaaa aacatttgaa agctattttt
     8941 caatacttca gatgaatcgt tcttattaca aaacaaactt ttgtatcacc ggttattcgg
     9001 aatttgagta aaagtgtggg gtaggactga tgtcccacct ccttttttta taaataagga
     9061 gattgtgtat ggaaaaaaac aggaagttca acctcgtcgc aactgcggca agcgggctag
     9121 aagcactggt tggtaaagaa ttaagagatc ttggaatcga atgccaagtt gagaacggac
     9181 gtgcacgttt tgaaggaaca atggaaacga tcgctacagc taatttatgg ttacgtacag
     9241 cagatcgagt aaaaatcgtg gttggggaat tcgatgcgta tacgtttgat gaattgtttg
     9301 aaaacgtaaa agcattgcct tgggaagatt ttcttccact agatgcagct tttcctgtag
     9361 ctggaaaatc gatcaagtcg aaactatata gcacacctga ttgccaagcg atcacaaaaa
     9421 aagcaatcgt tgaacgtctc cgtacctatt atcaccgtcc agcttctgta ccactgacgg
     9481 aaactggcgc acattttcag ttggaagtag ctttgctgaa agaccatgtg atggtaactc
     9541 tggatacgac aggaccaagt ttattcaaac gtggttatcg cttagaaaaa ggtggagcac
     9601 cattgaaaga aaacatggca gcagcactta ttatgttgac aaattggcga aaagaccgtc
     9661 cattttatga tcctgtatgt ggttcaggta cgctttgtat tgaagcagcc ttaataggcc
     9721 ataatatcgc accaggattc aatcgtgagt ttgcttgcga atcttgggat tggttcagtc
     9781 aagaaatcat ggaaaatgtt cgatcagcag ccgaagaaaa agcagattat gatattgaat
     9841 tagatattac tggttcagat atcaatggac ggatgattga aattgccaaa gccaatgcag
     9901 aagaaatcgg attaggctct tcgattacct ttaagcaaca agcagtcaaa gacttcaaaa
     9961 cggataaaga atacggggtc atcgtggcta atccgcctta cggagaacgt ctaggagaag
    10021 aagaaactgt tcggaaatta tataaagaaa tgggcgatgt attccgtcca ttaaaaacat
    10081 ggagtaaata tatcttgact agcgacttag cgtttgagga attttacgga caaaaagcaa
    10141 ccaaaaaaag aaaattgtac aatggtgcat tgcgtacgga tctattccag tattggggaa
    10201 ctcgtccgcc tagaaaaaaa gagaaagacg aataatctta ctaattgatt cattcaattg
    10261 gatgtttgga ggaataggga atgaaagaaa aagagttttt acaagaagta aaagaaatca
    10321 atcttctaca acaagcttta ggaatcctcg attgggatac acaaacaggt atgcctgaaa
    10381 aagctagtgc ataccgaagt gaagtagaca gctatcttta cagcatttat ttttcaaaaa
    10441 aaatcggtcc aaaaatcaaa gaagccattc gctatttttc tgaacatccg gaagaattgt
    10501 cggaagttgg aactgccgtt tttgccaaag taaaagaaga gtatgatttg gaacatcgcg
    10561 taccggaaga tcttatgaga aaatatacag ctgccgtttc ttcagcacac ggacaatggc
    10621 aaaaagctag agaaacacaa caattttctg attttcaaca cgcattgaat caaaatattg
    10681 aattaacaaa acagttgata ccttactgga gaaaagatga aaagacgaat tatgatgttt
    10741 tgctgaatca atacgaaccc gggatgactg tcgaaatcct tgataaggta tttgatcagc
    10801 ttaaagaagg aattctttcg atccgccgta cgctccaaga aaaagggact gaacctgaaa
    10861 cagacttttt aaatcggaga atgacgaaaa aacaacagaa gagatttgta gtgaaagtaa
    10921 tcgaacaact tggttatgat tttagtcgtg gtcgtttaga tgacactgtc cacccattta
    10981 tgactggaat taatccgaat gatgcacgaa tcacgacacg atggaacgaa acagatttca
    11041 aaatggctgt ttttggagtg atccacgagg ctggtcatgg tatgtatgaa caagacatcg
    11101 atgataaata tgcgtataca ccggtttatg aaggtacatc aatgggtatc catgaatcac
    11161 aatcgttgtt taacgagatc attattggaa gtagtcgcag cttctggaaa aagcaatatc
    11221 ctttctttca agaatgtgca gaaggaacat tcgatgatat tccttttgac aaattttatc
    11281 gttcattgaa ccatacaaaa tcaagtttgg ttcgtatcga ggcagacagt ttgacttacc
    11341 ctctccatat catcattcgt tatgaaatcg aaaaaatgat tttcaatgaa ggggtagatg
    11401 ttgctgaact acctgaaata tggaatcaaa aatatgaaga gtatctggga atacgaccaa
    11461 caaatgatgt ggaaggcatc ctacaagacg ttcattggtc aggtgcaagc tttggttatt
    11521 ttccctctta tgcattaggg tacatgtatg cggcacaatt acttcattct ttgcagcaag
    11581 aaatagatgt ggaaaatgtt ctagcgtcag acgattattc tccaatcaaa aactggatgt
    11641 cagagcatat ccatcaatat ggtgcatcta gaaaaccaaa tcaattaatc atggatgcaa
    11701 cacatgaacc gcttaatccg caatacctga tcgactatat gaaagacctg tattttaatg
    11761 tatatcaggt aaaataaaat acaatttaca aagatagctg aaattcatct aatctataga
    11821 tgttttcagc tatttactta agaaagaagt ggaacgaatg gataaattac aagtgatcgc
    11881 tgattatagt atggaccaat tagcgcatga tcaaacagga catgggagcg atcataccaa
    11941 aagagttgtc aagttagctg aaaaaatttt ggagacggaa ccgcaggcag accgctttgt
    12001 gacgcttgca gcagcttacc tacatgatac gattgatgat aaagtcgtta aaaatgagaa
    12061 cgaggcaaag caacagcttc gtgtattcct tcgctctttg ccaatagtag aggaacagat
    12121 ctcgatgatt ttttccatta tcgaaaatat gtccttttct aaaaatctct ctgaagcggc
    12181 cgaactatct ctggaaggta agatcgttca agacgctgat cgtatcgaag cattaggagc
    12241 aatcggcatt ttgcgtactg cttatttcgg cggtggacat gggcacccga tttttgatcc
    12301 tgaactgtat ccgcaaacat tcaaggacaa agaaaattac cgaaaaggca cgacagtgat
    12361 caatcatttt tatgaaaaac tgttcttgct gtctgataaa atgaatactg attacggata
    12421 tgaagaagcc aaacgaagag aaaccttcat gcgtgaattc ttagaagaat tttttctgga
    12481 atggtctatt gacgatgaaa attttactcc agacaattgg atcaaaaata acaaaaaatg
    12541 atggaggttg tgacagaagt ggtcagctcc aagatatttc ggatcatttt ccgtaaaagt
    12601 tacttctgga acactgttta ccaagaggtc gtgagcctgc cgttcagctc cgagtcacaa
    12661 ggaacaattt caaaaaatag cttctcgtgt ttgatgaata ttgtaacttg tgattcggaa
    12721 ttggcaggag aacaccgttt att
//
LOCUS       DAFENC010000061        12734 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.063, whole genome shotgun sequence.
ACCESSION   DAFENC010000061
VERSION     DAFENC010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12734
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.063"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(86..265)
                     /gene="rpmF"
                     /locus_tag="LP493_002457"
     CDS             complement(86..265)
                     /gene="rpmF"
                     /locus_tag="LP493_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBL2134569.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(323..892)
                     /locus_tag="LP493_002458"
     CDS             complement(323..892)
                     /locus_tag="LP493_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HBL2134570.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1078..1980
                     /locus_tag="LP493_002459"
     CDS             1078..1980
                     /locus_tag="LP493_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL2134571.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="LP493_002460"
     CDS             complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="LP493_002460"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HBL2134572.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="LP493_002461"
     CDS             complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="LP493_002461"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBL2134573.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="LP493_002462"
     CDS             complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="LP493_002462"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HBL2134574.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8548..8733
                     /locus_tag="LP493_002463"
     CDS             8548..8733
                     /locus_tag="LP493_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HBL2134575.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8795..9991)
                     /locus_tag="LP493_002464"
     CDS             complement(8795..9991)
                     /locus_tag="LP493_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBL2134576.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10161..11597)
                     /locus_tag="LP493_002465"
     CDS             complement(10161..11597)
                     /locus_tag="LP493_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBL2134577.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11890..12699
                     /locus_tag="LP493_002466"
     CDS             11890..12699
                     /locus_tag="LP493_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL2134578.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3801 a         2673 c         2250 g         4010 t
ORIGIN      
        1 tattttttat ttaccgacta caaaaaaata aacctcaagg ctccatggtt agccttgagg
       61 ttttacattt tctaattaaa atgtattaag cttcttttga cattacgtcc ttaccatcat
      121 agtaaccaca atttgcacat acgtgatggc tttttttcat ttcaccacag tttggacatt
      181 cgtttaaccc tttgattgtc aatttgtagt gtgtacgacg ttttgctttt ttagcttttg
      241 atgttcttct agctggtact gccattttgc tacacctcct tgtaaagtct tgtatctaaa
      301 ttagacacaa tatattccaa tcttacttgt tatcgtcgtc ttttgattta gaatcaaaaa
      361 gttcagatag ttttgcaaga cgaggatcaa ttttattctc ggcttcttcc atttttctgc
      421 gctggtattc ttcttcggaa acaacttccc aatcattgcc ttttggaagt tctgttgctg
      481 cttcctcttc ttttgtcaat acccgcattg gaatcgccaa taagatgttg tcttcaatcg
      541 actctgctaa attcaataat ggaccttcaa ttagcaaaat ctcatctgca gacatttgtt
      601 catctctact ttggaattgt tcttctgtca tgaatacttc gtctacagaa aaatccatgg
      661 gcagttcaac aggttctagt gaacgtgttg aaggaactgt caaagtcgtc tgcacagtgt
      721 aatgaacgat atagcctttc ttatcaactg agaccaaacc ttcgacttcc actggcgcaa
      781 catcaagtat taaattgtct cgcttcatga gagcggcttt caagtcgagc gtctcatgaa
      841 aagttaacgg tgtctcctgg tattttctca attccaataa agaccatttc atttttcatc
      901 actcctaagc aacaaaagca attatacagg gcaaaaagca tgttgtcaat gaaattttct
      961 tgacaccttg cagttcataa aaaaacagaa aaatctttat tagaaagcct ctgtttgcta
     1021 tcatcctcag aatcatttac aataatcatt attccattaa aggagcggat gatcttcatg
     1081 aacacgaaag atatcgaata ctatgtccaa atcgtcaaac aaaaaaattt tacgaaagtg
     1141 gctaattatt tccgtgtgag ccaacctact attacatatg cattacaacg tcttgaaaaa
     1201 gagtttgaca ccgtacttat tacaagagat cgatcgcatc acgaattaat cgtcacgcct
     1261 tctggaaagc agctgtttct ccatgcacaa accattctcc aagagatttc tactgcaaga
     1321 gctgaaatca ctcagttgca aaagaaaaag cttcgttttg gcatgcctcc tattatcggc
     1381 aatgaatact ttcctaaact gtcaagttac tttatcaagc atgaattgat gaatcaaatt
     1441 gagattaccg atggaggctc tcgggactta tacgggatga tccgacaagg gaggatcgat
     1501 ttagctgtat taggctcaac acagccaatc gtggatcaat atttagaaac agagttactt
     1561 ttggacaaac gtttcatgat cgtcgtgcca cctacacatc ctctttccaa gcaggatact
     1621 gtctctttca aagatatagc agatgaacag tttgtactat tgaacgaaca ttatgtccac
     1681 cccgcagcat tcactaagct ttctaaacaa acacatactc atccaaaagt tgtttatcaa
     1741 agcaatgact tgacgatttt aaagagtatg gtccgagaaa atgtgggtat cggttttttg
     1801 gcagagattg ctgtccatcc tgaagatcat ttagtttgcc tccctctttc agatgaagtt
     1861 cagcctcgct tcttgatttc attggcaaaa cgaacacagc agatcgtcac gcctcttcaa
     1921 gaacaagtag tccaagttat ccatgaattc gttacagcac aaaaaaacag ctcttcgtaa
     1981 aagaagagct gtttttattt tttattaagc taaattagat agctgttgtt tcgccacggt
     2041 aaacgatgcc gcgacgtgaa tcaacggtaa tcaattcacc ttctgtaatt gttgttgttg
     2101 cgcctttagc accaacgatt acaggaatat cttgtgcaat tcctacaact gcagcgtgag
     2161 aagtcaatcc gccttcttca acgataacag cagctgcttt ttcgattgca ggcatatatt
     2221 ctttgtcagt tgatggtaca actagaacca ttccgtcttt tgcttttttt acagcttctt
     2281 cagcagatga agcaataact gcatttgcaa cgacagattt ttgtccaacg ccttgagctt
     2341 ctaataattt agaaccaatc atttgaattt tcatcacgtt agttgttccg cgttcaccaa
     2401 ctggtacacc agcagtgatc aagattaaat cgccttctga tgcgaaacct aattcaacag
     2461 cttttttagc tgctagttca aacatttcat cagttgttga tggtttttca gcaactgttg
     2521 ggtaaacgcc ccagtttaac atcaaaccac gttttgtgcg ttcgtcaaaa gtaacagcca
     2581 agatatctgc atctggacga tattttgaaa tcatttttgc agtgtatcct gattcagttg
     2641 cagcaacgat tgttttcacg cctagatttt ttgcagcacg agctacagat aaaccgattg
     2701 tttcagttac atctgtttta tcgaattcgt tcaattggaa tgtacctaat tctgataatg
     2761 cattttcagc ttcttggtcg atacgtgcca ttgttgaaac agcttcaact gggtagtccc
     2821 cgtttgcaga ttcaccagat agcattgttg catctgtgcc atcaaataca gcgttagcaa
     2881 cgtcagaagc ttccgcacgt gttggacgtg ggttttcttg cattgattct aacatttgtg
     2941 tagcagtgat aactgggata ccagcagcat tacatttttt gataatgcgt ttttgaacca
     3001 ttggtactag ttcagctggg atttcaacac ccatatctcc gcgggcaatc ataacaccgt
     3061 cagaaacttt gatgatttcg tcaatgttgt cgataccttc ttgagattcg attttaggga
     3121 agatttgaac atgagtcatg tctttttctt ctaagatttc gcggatatct agaacgtctt
     3181 gtgctttacg tacaaaactt gcagcgataa agtcgatatc gttgtctaaa ccaaaacgaa
     3241 tatcgtcagc atcttttgga gtaatacctg gcaaactaat agaaacgcct ggtgcattta
     3301 cccctttacg tgatcctagc atacctgcat ttttaacttc tacgactaat tcacggtttg
     3361 cttcgtcttt ttcaatgatt tgcatatcga tcaaaccatc atcaaataaa atgtgtccgc
     3421 caacgtgaac atcgtcaaat aatcctgggt aagtaaccgc gattttttct tttgaaccta
     3481 catgttcagg atccatagag atgcgtgttt gatctcctac ttcaaatttg atgtatcctg
     3541 cacgaccaaa atcagcttct gttgtgcctt gaacagttgt acggatttca gctccttttg
     3601 tatctaaaag aataccgaca tcttttcctg tctttttaac tgcttcacgg accatagtca
     3661 tacgtgataa ttgttcttca tggtcaccat gagaaaaatt aaagcggaag acatttgccc
     3721 cagattcaat caattgagaa ataatttcta ctgagttact tgctggtcct aatgtactaa
     3781 cgattttggt ttttttcatt taaaaaactc tcccattcaa ttttgtttat ttaaagctgt
     3841 acacagctta aatagcttgg tttctttcac tcttaaaatg aaagtgaatt atttagatca
     3901 tatagtgata agtctggttt atgtttgttg ttttcaagtg tatcaatgat gtcagacgca
     3961 acgatttcgt tgtcatggat accgacacat aatccacctt ttccttcttg aagcaattcg
     4021 acagcgtaag caccgaattt acttgccaac acgcggtcgc gtgcgcttgg tgctccacca
     4081 cggacaacgt gtcccaagat agatacacgt gtatgatagt caccaaattc tgaaagtttc
     4141 tcagcgaatt catttccgcc cattacacct tcagccaaga tgatcaagca atgtttcttc
     4201 ccgcgatcgc ggccttcttg gattttttta gcaactgaag ccatatcaaa atcatgttct
     4261 gggatgatga tttcatccgc tccgccagcc acacctgacc ataaagcgat gtctcctgca
     4321 ttgcgtccca ttacttcgat aacgaatgta cgaacatgag aagtcgctgt gtcacgaata
     4381 cggtcaattg attctagtac tgtattgatt gctgtatcaa aaccgattgt gaaatcagtc
     4441 ccaggaatat cattatcgat tgttccagga atacctactg ctgggaaacc gcgttttgtc
     4501 aaagccattg cgccatgata agagccgtct cctccgataa ccactagacc ttcgattccg
     4561 aattttttca attgttcgat tccttttaat tgaccttctt cagttgcaaa ttctggataa
     4621 cgtgcagaat acaagaatgt accaccacgt tggatcttgt cacctacatc tgccacatca
     4681 agacgacgaa tatctccagc aactaaaccg gcaaaaccat aattgatccc gtatacttcc
     4741 agtccttcgt aaataccttt acgaacaacg gcacgaacag ctgcattcat tccaggtgcg
     4801 tctccgccac tggtcaaaat tccgatgcgt ttcataataa acattcacct cattaaaata
     4861 ctttatccta agtatgactt aggtttacaa ccatttttgc gttaaccacg actaacattc
     4921 taacattatt tttctcactt gtcttgattt acggataaaa aaatgaaaaa aaatgaaagc
     4981 aagtagtatt ttttaccgta agttatttga aaaccacatt atcttcgcca agcagataaa
     5041 taagttgccc ctttatactc ttgctgtcat ccacccaata agcatctgac agaactactt
     5101 ttcgttgcgt tttttcgtga tacataacta ctggtatata tcctgggtgt ttctgaaaaa
     5161 tcacttgtaa ttgtttcatt atctcgggat cttcccgttc ttctgtaata cgcaaatagc
     5221 aagtttgtga aggatactgg gcttctaact ggttaggatc agcaaagctt tctccaatta
     5281 gttgcagttc ctgattatat ttgctgattt cgctccgccc ttgaacaaag atcactcgat
     5341 caacggcaaa caaattacga tatttacgat aaagagttgg aaaaactgtg acagaaattt
     5401 ctccactact gtcggttcct tcaacaaagg ccatcagttc tccttttttt gtccgaattt
     5461 ctctaacttc cttgatcatc actaataaat tgactggttg attagggacg atatctgtaa
     5521 tcagctgaac ttgtttagct aaacgaagac gatcaaaccc ttctgcagga tgacctgaca
     5581 aataaatacc taagtactcc tcttccagct tcaagcgttc ttctagtgta tagtcagcga
     5641 cttcttcttc ttttaatgcc atgattccca gcaagtcaag acttccacca ctgtaaacga
     5701 tattttggat ttttccttcg agatcaagca tcaattgttt cctgttagga gataattcat
     5761 caaaaactcc tactgctgtc agtgattgca gtaactctaa tttcagccaa cgcttatcga
     5821 tccgtatgag gaattgatcc actgactgga acgggccatt ttgttttctt tcgtttaata
     5881 tatcttctac aaaatcacgc cgaatacctt ttatcgctgt cagtccgaat ctgatttctt
     5941 ccttattgac caactcaaaa ctggaattac tttgattaat ggacggcgag gaaagtttga
     6001 gtttattttt acgtgcttct gcaatatatt ctttcaattt tgatgtgtta tgccgaacag
     6061 aattcatcag gctggtaaag aaagcacctg gatgatgggc ttttagatac gccatttgga
     6121 atcccacgaa tgaataagca aatgcatgtg accgattgaa tccatagttt gcaaattttt
     6181 cgatatattc atatacggtc gctgctgttt tttccgaata tccctgttgt aatgctcctg
     6241 atacaaaatg cgacttttct tcatctaata cgtctttttt ctttttactc actgcccgtc
     6301 gcagaatatc tgactgccct aatgtaaatc cagccatagt cgaggcgatc tgcatgattt
     6361 gttcctgata gacgatcact ccatatgtgt ttttcaaaat cgggatcagt gaatcatctg
     6421 ggtagcgaat ggcttctttt cctttcttcc tggcaatgaa ggtatctata ttttgcatag
     6481 ggcctggtcg atacaatgca ttgactgcgg caatatcttc gatgttttct ggatctaatc
     6541 ttcgtaaaac gttccggata ccagcagatt caaattgaaa tactcctgag gtttcgcctc
     6601 gttgaaacaa gagcagcgtt tttgcatcat ttagcgggat ctcttttaat cggatctcat
     6661 acccttctac tcgcttaaca gctttcaaag taaaatcaat aatcgataag ttgcgtagtc
     6721 ctaaaaagtc cattttcaaa agaccgattg cttctacctc attcatcgta tactgggtca
     6781 gaaaagcttc atcagaaccg cgttggagcg gaactagttc aagtagattc ttatcgctga
     6841 taactacacc tgctgcgtga gtcgaaacat gtcttggcaa tccttctaaa atcactgcag
     6901 ttttgaataa aagttggttt ttttcgcttg cctgaactaa ttctactaat tgatgcgaag
     6961 ttttataagc ttgggtcaat gtgattttca attgattggg tattgctttt gaccagcggt
     7021 ttgcttcact ttgcgataaa ccaaacactc tagctgcatc tctaagaacc atttttgctg
     7081 ccattgtgcc aaatgttgcg atttgtgcca tatgatattg tccatacttt tctcgaacat
     7141 aattcaatac ttcttcacgt cgattgtcag gaatatccaa atcgatatct ggcatcgtaa
     7201 agcgttcggg gtttaaaaag cgttcgaaca gcaaatcata ttctaatgga tccacatctg
     7261 tgatttctaa cacataggct actaatgaac ccgcagcaga accacgacct gcaccggtaa
     7321 cgattttgtt tctatgagca aaagccatta catcccatac gatcaagaaa taatcatcga
     7381 atcccatttg atggatgaca gataactcgt agtccaaacg ttcttggtat tcctttgtat
     7441 agtcagtgat tcggcgttcc acttgcgaat agcataactc tcttaaatat tctccagctt
     7501 gttttccatt aggaactgga taatgcggaa gtaatttctg atggaactgg aattcaaatg
     7561 aaatcgattc agctaaacgc tgggcgccta ttacagcttg ggaaagaccc gctttttcga
     7621 atcgtttgat catttcttgt tctgaaagaa gatagacatt tgctgttagt ggtaaagatg
     7681 cagataaatt ttctaaaggt atttggcttc cctctttgat atgtttcatc acttcaagtg
     7741 caaaaagttc ttcttgttgt aaactagcga tgggatgtaa tgcacaaagc gaataatttt
     7801 cttttatcac atactgatac cattcaggca attgatcagg cgtgttttct gtcaagccga
     7861 tataaaaatt tctagtaaaa acattttcaa gtaaaaactg ccaatgaccg aaaaagttat
     7921 cctctttatt gaaagcctca gaaacagaat gatttgccgg aacaacaaac gctagatggt
     7981 cggtttctgt catttctgca agttccaatt tttcttggat catttttcgg ctggaaagtt
     8041 tcatcagctg ctgataacct atttcatctt ttgcgtacgc aagcaagcca taattttttt
     8101 cttcataagt ataactaaga tgtaatccaa tgattggctg tactccttct tctacacaaa
     8161 tacgatagaa ttcaggtgca ccgtataaga catctttatc cgttatggct aatgaagtgt
     8221 agccttgttt ttttgcttct tgtacatatt ctcgaatacg tatcgtactt tgtaaaagag
     8281 aataagaagt aattgtataa agttgtggga aaaacatctt gcattccgcc ttttttttcg
     8341 ttaaaattca ctagcgttaa aaggtttgat ccttttactt tcattaagat agcaggcgct
     8401 gaagttgatt attccacttc atttgcttgc ttgtaatctg taggaatgag ttctttcgca
     8461 agaactcaaa ttttattgag atttggtctc gtttctttac attcaaagaa aatctggtaa
     8521 aattaagata gaaaagaggt gttctttatg cgatatatcg ttacattatt ctgggctgtc
     8581 gttctaggtc aagtagtcgg ttatattggt gctgcattaa caagcggaac atatgatttt
     8641 actttgacaa caatcatttc attcattgcg ggtgtcatta tccttttgat tggtgcagtt
     8701 gcgccaagaa aagaaacctc tgcccattcg taaaaaaaca gccaagagct tgagatttct
     8761 caagctcttt tttattttct actcctcacc accattataa tctgctgcga agaactttac
     8821 gaaagttgaa taaagaaaga agaatatttg acagaacaaa caaacttgtc acaataaaaa
     8881 cagcactgta attataagca tgcgcgactg tcgatcctag catgggacct aaaacttgtc
     8941 caaagttgct aaacatctga ttgtagctat agattcggct gactccttct tgaggcgtaa
     9001 tcttactgat cagtgtattg acagaaggca tcaaagcgcc agttgaaaag cctaaaataa
     9061 agcgaagtat acctaattgg agcggtgtag tgacgaatgc cataggtaaa taacagcaaa
     9121 atgataaaat gagtcctcca attagaactt tttgattccc aatcttatcc cctagttttc
     9181 ctagtttcgg tgaagaaaag acagcggaaa caccagctat cgaaacaatc aagccgctga
     9241 caaaaaggat attttctgta cttccgctca attcacgaat atataaggtc aaaatagggc
     9301 tgatcgtagt gattcctatc tgtaaaatca aggtcgtaat gaagagaccg atcaaaatag
     9361 agagatgatc catttttgaa aaaatttctt tggtgcttat cagatctttt ttctcgattg
     9421 gatggaaatc ttctttgact aagaaaatgg tcaataccgt tgtgatcatc aacaaagccc
     9481 ctgtgatcaa gaatacattt tccataccaa accactgagc cagtgcaccg cccattgaag
     9541 gtccgatcag atttccagca atcgctccgg tagacaatgt tcctaacgcc catccgctct
     9601 tttctctagg tgcctgtgaa gcaatcatcg ctgtggcatt tggaatatat ccagacaaaa
     9661 tcccattcca aaaccgcatg atcaaaagcc aatacgcgtt tggtacaaaa gccaaagatc
     9721 ccattgttaa tgtcatccct gctgctgcac ggatcatcat gagttttcgg ccttttcgat
     9781 cagctagatt tccccagatt ggtgcaacca cggcagatgc aaaagcagtc acagagattg
     9841 ctagtcccga aaacaattcg atttgatctt ttggtgttcc tagttgctca acataaactg
     9901 gtatgaatgg cataactaaa ctaatacttg caccagtgaa aaaacagcca atccacgcaa
     9961 tcactaaatt ttttctccaa ttaatctcca tctatcatcc ctctttcgtc tcttttatca
    10021 tacctatttt cgaataaaca agcaacgatc tcgccagtaa aaagagaaaa atcccgcaaa
    10081 ggtcatttta tatgtaacgt tctttttatg taaaacaaaa agagatcaga acaaatactg
    10141 ttccaatccc ttctctttag ttaaattgtt gctagaatga tgaagttgat aatgaataaa
    10201 atatcaacga tccacaaagc aacagaaact tgattgtatt ttcctttgat tactttcaca
    10261 attgtataga aaataaatcc tgctgcaatc ccataggaaa tgctatagca caatcccata
    10321 aagatcgatg caaagaaggc cggtaaagct tcttccatat ctagccattt gatgtctgca
    10381 aaagaagcca tcatcattac tccaactaaa atcaatgctg gcgcagttgc ttgatttggt
    10441 acaatggcga tcagtggaga gaataaacta cttaatgcga atagcactgc cactactact
    10501 gaagtcaaac cagtacgtcc accggccccg atcccagctg cagattcgac ataagttgtt
    10561 gtattcgatg taccaaagat agcccccaca gaagtagcga tcgcatcggc aaatagtgct
    10621 ttatccattt ttgttttgaa cccacgacca tcttccaacg cgatctcgtc ttcttttgag
    10681 aaaatacctg tgcggcgtcc tgtaccgata aatgttccga tcgtatcgaa agtatcagat
    10741 aaactgaatg cgatgatcgt catcaatact tgaggaatct tggaagaatc actgaataaa
    10801 gattgcatgc cttcagaacc aaatgctgca ccgaaagttg ttcctaattc tttaaatgaa
    10861 ttacctaacg aattcgtttg ccaatcaatg gaacttaaat caacaacacc cataaaaata
    10921 ccaaggactg tggtcgctac gataccgata agaatagccc cacggacatt ttttacaact
    10981 aaaatggctg tcagtaccaa accaatcaca gccaataaga taggagcgtt gtcaaagttg
    11041 gctaacgcag ggacgattcc accatttatc gtaacatttg tcgcttttcc gccttcaacg
    11101 acagagctcg aaatagctga ctggtctgct gaaaaagata agaatcctgc atttttgatt
    11161 ccgacatacg caacgaaaat accgatcccg ccaccaatcg catgttgaag actttcggga
    11221 atcgcccgaa taatcatttt tcgaatattt gtgacagtaa taaaaatatt gattaatccg
    11281 caaataaaca ccattgccaa ggcttgttgc caagaataac caagcccaaa aacgaccgta
    11341 aaagtgaaaa atgcgttcaa tcccatacca ggtgcctgag catatggtac atttgcgaac
    11401 aatcccatta ccagcgtacc aataatcgat gcaatgattg tcgctagaaa tactgcttgg
    11461 aagggcatac ctgatgctga caaaatcgtc ggatttacga ataagatata actcatggca
    11521 aagaatgtcg ttactcccgc cattatttca gttgatacat ttgtattgtt tttctttaaa
    11581 ccgaaaaact tttccataaa aagttccact ccctgaattt ttttctgatg gaaaactata
    11641 ataataaaaa ataagtaaaa tagggcaaat ccatcgaaca atttcaaatt atatagacgt
    11701 ttcattcgct tttcaacgtt tttttaacaa aaaaagcgaa aataatactt aacgttcgtg
    11761 tttagcttat gtttagctat ttatatagcc ataactgtag tttttgttag gaatagctga
    11821 ttgctcttgt taattaccta aaatatgcta gactaaaaca aatgctagtt gaggaaggaa
    11881 ggacccttat tgaataaaaa attaattgcc atcgatctgg acggaactac cctcaatcaa
    11941 gattcgatga ttacatctaa aacaaaagag actctaaaaa aagcaatcaa tgccggtcat
    12001 catgtcagta ttgctacagg acgcccattc cgaatgagcc atcagtttta ccaacaatta
    12061 gaattaacaa caccgatggt taattttaac ggcgcattag tacacatccc taatcagcac
    12121 tgggatggtg aaagagaaac gttgatcaat cgtgaaatcg cttttgaaat cttatcgcaa
    12181 aaaaagcagc taaatttaga ttttatcgct gctgaaaatc gtgatacttt ttttattgac
    12241 agttttgatt tctttgatga aaaaattttt gcttcttctc gtccaggaga gaagaatttg
    12301 ctttctccta aaaatttgac gacaaatcct acatctttgc ttgtccgaac agacaaacgt
    12361 tttgcaggag ctgtatctgc tgaattaaca cgtcaatttg gcagttatgt cgatgttcgg
    12421 acatggggtg gacctactgc catcttagag attgtttcaa aaggaatcca aaaagcaaaa
    12481 ggcgtgcaag agattgctaa ctacctgtct atcgatcaaa aagacgtcat tgcctttggt
    12541 gacgagcata atgatttgga attgttggat tatgcaggtt ggggagtagc tatggctaac
    12601 ggtactgacc aactcaaagg cattgcaaat gatgtcactc ctttgagcaa tcaggaagac
    12661 ggtttagctg tttatctgga aaaactactt aaactataat agagaattag attccacaaa
    12721 aaagaggttg tgac
//
LOCUS       DAFENC010000062        12728 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.064, whole genome shotgun sequence.
ACCESSION   DAFENC010000062
VERSION     DAFENC010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12728
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.064"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(241..1206)
                     /locus_tag="LP493_002467"
     CDS             complement(241..1206)
                     /locus_tag="LP493_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HBL2134579.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            1440..2285
                     /locus_tag="LP493_002468"
     CDS             1440..2285
                     /locus_tag="LP493_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL2134580.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            2476..3663
                     /locus_tag="LP493_002469"
     CDS             2476..3663
                     /locus_tag="LP493_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBL2134581.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            3669..4025
                     /locus_tag="LP493_002470"
     CDS             3669..4025
                     /locus_tag="LP493_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HBL2134582.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            4027..4365
                     /locus_tag="LP493_002471"
     CDS             4027..4365
                     /locus_tag="LP493_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HBL2134583.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     misc_binding    4441..4697
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            4760..5794
                     /locus_tag="LP493_002472"
     CDS             4760..5794
                     /locus_tag="LP493_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBL2134584.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            5787..6473
                     /locus_tag="LP493_002473"
     CDS             5787..6473
                     /locus_tag="LP493_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2134585.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            6497..7345
                     /locus_tag="LP493_002474"
     CDS             6497..7345
                     /locus_tag="LP493_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBL2134586.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            7542..8315
                     /gene="sufC"
                     /locus_tag="LP493_002475"
     CDS             7542..8315
                     /gene="sufC"
                     /locus_tag="LP493_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HBL2134587.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            8328..9614
                     /gene="sufD"
                     /locus_tag="LP493_002476"
     CDS             8328..9614
                     /gene="sufD"
                     /locus_tag="LP493_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HBL2134588.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            9611..10846
                     /locus_tag="LP493_002477"
     CDS             9611..10846
                     /locus_tag="LP493_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBL2134589.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            10833..11303
                     /locus_tag="LP493_002478"
     CDS             10833..11303
                     /locus_tag="LP493_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HBL2134590.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            11308..12699
                     /gene="sufB"
                     /locus_tag="LP493_002479"
     CDS             11308..12699
                     /gene="sufB"
                     /locus_tag="LP493_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HBL2134591.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKCEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
BASE COUNT         4209 a         2383 c         2808 g         3328 t
ORIGIN      
        1 gaagtagctt ctacggaaat aagccgaaat ttcacaaaaa tttgagaagc aattttcgta
       61 aattccttct tatttcttga agctgaccac ttcttttacg acctcttggt aaacggtgtt
      121 caaaagcttg catctgcggt aataagccca accagtacaa aaacatgaac agctgttttt
      181 gtttggccgt tcttattact tgatgcagaa cagctttttc acaacctatt gaatcgatta
      241 ttaagcgatt tttttagaaa caaattttcc atgtttgcta tgttctttaa ttaagaaacg
      301 tacgtaatga gcaagaacgt agaagacaac tacacttgca aacagacatt ccgcaacttt
      361 taagaaatcc aatacgctac tatagatacc taaactgttg aagtaatgaa cagtagtaaa
      421 tatagctgtt gcagagataa caagcgggaa tgtaaaggct gcatagcttg gataaaaacg
      481 aagcttgaac aaacgtggaa gcatagacag cacaacgaaa tacaatactt gagataaagc
      541 gaacaatgct acgacaagat aaaaattagg ttcagcaaag tttttaagat aacctgttag
      601 gcaaagagaa ccaggtgctg caacgatcgt aatcagcgga cgtgtcggat gagccatatt
      661 tcttacgaaa aagacacgtt tgatgatgat cggcaataag aacgcatagc agatcaatga
      721 aatccaaaag aaaatttttc caataagtgg gaagaagttc ccggcagtta cagtgatgac
      781 cccaaatcca acgtaaatga taaaccagct tggataaatt gcttcaattg aaagatcagc
      841 tttgataaca tggtgataat tgaaataaaa gacaaggatc acttggaaga taacagcgca
      901 cagccaaatg aatttgacaa ttggtgcaat actttcatat gaaacaaaat aagtacaaat
      961 aaccatgagt gacatcgtaa aagttggtga aacggaggcg atgattggat catgcaacgt
     1021 ttgtttcgtg tgttcgaata agataaacaa tttaacaaaa atgaatatca taagaatcat
     1081 agagataccg ccagttagat tgcctaaagc aacatggtga tagtctttaa acagatttcc
     1141 aagggaagct aacccaagga tcaacccgca gatcgggatc ggaataattt tcaaaaagtt
     1201 cttcatatat aatattctcc tttttattta atagatttta gtaccaagat gaacgaatac
     1261 attgtaaaat gaataggaat gtatgattac gagcaagcag acagctgatt gtcttcatct
     1321 aagttactag ttggatcagc aactgttttg ttgtacattt ctattataga tggttttttg
     1381 tatatttaaa tcaaatagtt tttatagtaa ttatcataaa aagttatgga agtggtgcca
     1441 tgtttaagtt attaacgact tttcgagcag tatatgaaac aagaaatttt tccagagcag
     1501 cagaagtact gtttttatct caaccagcag tctcgaatca aatcaaacag ttggagcggg
     1561 aattgaatat cgatcttttt caacgtaacg gaagaaaaga gatgcttcca actaagcaag
     1621 ccgacttatt atatgaacgg acactggttt tgttagaaga atgggaagaa actcagcaaa
     1681 aattgctcaa tgaacaaaat gaagaagaag tatgtcggat cgttgcttcc cacacctttg
     1741 ctgtctatct tttgcctcag ttgatgaaac atctgatcaa aaggtttcct aaagtgcatt
     1801 ttgagatcga aatcacgaat tctcatgaat cattagaaca agtagcgaaa catgaatccg
     1861 attttggttt tatcgaaaag ccattagaga cttccggcgt acaaagatac tctttgatgg
     1921 aagaccagct agtcatcgct ggggacccaa aaagcaaatt gtggcttgta agagaagcaa
     1981 actctggtgt ttttcattac acgcagcgtt attttgaaga gatgaatatc caagataaga
     2041 agatgatcgt gaaaagtaac gatgtaattg ttgcgttgct gaaggaagga atcggtcgct
     2101 cgattttgtc taagcgctct gttccagaaa atgtgccaat gactccgttg aatttccatc
     2161 gatattttta tttcatccaa cgaaccaatc tggtttctga tcagctgcta gagattgccg
     2221 aagagatcct tcgatacaat gaaagcacag aaacttctca cagcgaggag aatctcagct
     2281 ggtagataat tgcatgtatc aaaaaaagtt ctatgataca ctaaagataa gcagtaggct
     2341 tttgtactgc atttgctcaa gcaactgcac aaacggaaag ttaatttttc ccaaatgtct
     2401 atggaaagac tttccattat ctaactggac cgctataata atcagcagta tggtttttaa
     2461 gaaaagggat gaaacatgga aaaaaaatta aaagcttcga acgataatcg tattgattat
     2521 ggcgtgattt taccagtctt tctgttatgt ttgattggtc tgctctcatt atatgtagca
     2581 cttagccatg atccgaacaa tccagcagtc ttgaaaggcg tagggatgca agttgtctgg
     2641 tatttagttg gagcggcagc aatcgttgtc atcatgcatt tgaattccaa atggatctgg
     2701 aaactgactc cttaccttta tggtttgggg ttagtggtaa tgggactctt gctcaaattc
     2761 tatgatcaga atttagctgc ttcaacaggg tctaaaaact ggtttcgatt cggtgcgttt
     2821 actttccagc cagcagagtt gatgaagatt gcgtacatct tgatgatggc actgatcgta
     2881 actaaacata atacgcaagt aaaagaacgg acgatgaaat cggacttttg gctgattggg
     2941 aagctcttga tcgtgacaat accggtttta gcattgatca tggcccaaga tgactttgga
     3001 acgatgcttg tctttcttgc gatctttggc gggattttcc tgatgtctgg aatctcttgg
     3061 cgcatcatcg cacctgtagt aatcttggca gtagtcgttg gagcaggaac gatcttcttg
     3121 gttacgactg aaggcggaag agacttgctt tataaagttg gattcaaatc ttatcagttt
     3181 gcacgtattg attcatggct ggaccctttc catgatacgt caggaatgag ttatcagccg
     3241 gcccaaggac ttttggcaat tggtaccggt ggcttgtttg gtaaaggatt caacgtaagc
     3301 aatatctatg tgcctgttcg tgagtccgat atgattttta ccgttatcgg tgaaaacttc
     3361 ggctttatcg gtggtgcatt cgtcattttc ttgtatttta ttttaatcta tcgtatgatt
     3421 cgggtgtgtt tcgatacgaa taatgaattt tacgcctata tcgcaagcgg tttgatcatg
     3481 atgctgctgt tccatgtctt tgagaatatt ggagcaaata tcggattact tcctttaaca
     3541 gggatcccat tgcctttcat tagtcaggga ggatcctcga ttttagggaa catgatcggt
     3601 atcgggttga tattatcgat gagataccaa aatgaagcac ctgcaagatc ttcaaggagg
     3661 taagaaaatt gtacaccttt tactggtacc cgaaatgttc aacatgcaaa aaagccaaag
     3721 cgtggttaga ccagcatggc gttagttatc aaaccgttga tatgatcaaa gaagtaccga
     3781 aggcctcaac gattgagact tggctagaaa cgagtcaagt accaatccgt cgcctgttca
     3841 acacaagcgg gatgaaatat cgggaacttg gactgaaaga tcaagtaggc gagtttacgg
     3901 cttcaaaagc gagccaagtc ttatcgacag atggtatgct gatcaagcga ccactgatct
     3961 tacgagagga ccagcttgtt gcaattggat tcaatgaaaa aatttatgaa ggagaactga
     4021 tataaaatgg caggcaagca tttgaagaaa aaggacaacc tttggatctt atttaatgga
     4081 aaagaatact gtgttggttt gacaaatgaa gcgcaagaag aacttggaga catcacgttt
     4141 gccaatctgc caaaagcagg acaatcgcta aaaaaagatg aacctctgat cgaagttgaa
     4201 gcggaaaaag cggtcaatga atttgccagc ccgctaacgg gtacagtttc ttctgttaat
     4261 gataaaatcg gtgaagatat caatatcttg aatgattcag atgaaatgaa tgcgtggatc
     4321 ttaagtttca aagatgttga tccaaaagaa tttgacgaat tataaaatca gaaaatcact
     4381 tgaaaaaagt tgacactgat tcttccagtt gctataatca taagcaatcc tatatgaaac
     4441 gagaaagctt tgaaaagaag agtacatgtc acggacgttt gaagagagcc ctgtttgctg
     4501 aaaatgggta acgaaaatga gatggaagat ggtcttagag cagagtaagc gagcgtaagc
     4561 aaacttacta cgggagtgcc cgttacagcg cgacagtata cggaaagaag ctaagtccaa
     4621 gtactggaag aggctgttat tgcgaagtaa cggtaaatca aggtggtaac acggaagttc
     4681 aagctttcgt ccttttgctt aaggcaagag ggcgaaggct tttttgtttg aaaaattata
     4741 agagaaagat gtgaatggca tgtcattaat ccaactaacg aatgtcaaaa agacattcaa
     4801 tgggaaaaac ggaaacatcc aagccgtcaa tgacgtttca ctaaacgttg aaaaagggga
     4861 tatttatgga atcgtcggct attctggcgc aggaaaaagt acattagtcc gtctcctgaa
     4921 tggacttgag cttcccacga gcggcgaagt gatcgtaaac gatcaagata ttacaaaatt
     4981 aaaaaacaaa gaattacgta cattccgaaa gaaaatcggt atgatcttcc agcatttcaa
     5041 cctgttatgg tcaagaactg tacttgaaaa tatccagctg ccgctggaat tagctggcgt
     5101 accaaagagc aaacgtaaag aacgggcaga agaactgttg cgtttagtcg ggttagaagg
     5161 acgcggacaa gcatatcctt cacaactttc cggcggacag aaacaacgcg tcggtatcgc
     5221 acgagcattg gcaaatgatc ctgagatcct gctttgtgat gaggctacta gcgcattgga
     5281 cccgcaaaca acagaagaag tattagactt attgttagcg atcaataaga aattgaattt
     5341 gaccatcgtc ttgatcacac atgaaatgaa tgtgatccgc aaaatctgca acaaagtcgc
     5401 tgtgatggag ttggggaaag tcgtagaaga aggagacgta ttgactgtct tcagacaacc
     5461 gaaaaaagaa gtaaccaaac gctttgtaca acaagacatc gaaccagaag ctgattcgac
     5521 agaactatta gctgaactca tcaaagaaaa tccaagcggc cgtttggcaa ctttgacctt
     5581 tagcgaaaga aatgccaacg agccagtcat ttcccaagcg attcgacgct ataacatcga
     5641 tgtcaacgtt gtgtatggaa agatcaaaca agtgaaagaa ggttcctttg gttcattgac
     5701 tgtcttgatg actggtgaaa ccaaagaatt agatcaagca gaagtgttca tcaaagaaca
     5761 aggagtagga attgaggtga tccatcgtgg ataaaagctt ttcagaaaca tatctagatt
     5821 ttaaacaaat caacccggaa acgatgaatc aggctatcct tgatacacta tatatgacat
     5881 taatctcaat ggtcttagtg acgatcatcg gattagtttt gggattgatc ctttactcta
     5941 ttggacgcaa aaacaaaccg tatgctcgaa tcatttatgg aatcgtatcg atcatcagta
     6001 atattttccg gtcaacgcca tttatgatcc tgatggtttt gatcattcca tttactaaag
     6061 caatcgtagg cactatgcta ggtgcgcaag cagccattcc agctcttgtt ttatccgcag
     6121 caccatttta tgcccgtcta gtagagattg cttttcgtga agtcagccct ggtgtactgg
     6181 aagcagcaga tgcaatggga gcaagttact gggaaatcat ctggaaggtc ttgatacctg
     6241 aaagtattcc cgcattgatt tctggattaa cagttacaac gatctcgatg atcggattta
     6301 ctgcgatggc cggcgcgatc ggcgcaggtg gacttggagg tcttgcttgg caggaaggct
     6361 accagcgtgg taatctaaca gtgacattcg ttgcgacttt aattatttta ctaatcgtat
     6421 ttatcgttca aggaatcggt gatttcttaa ctaagaaaac agacaaaaga taataggata
     6481 tagggggatg taggatatga aaaagaaaat ttttggattt gcagcagcgc ttttgctgac
     6541 tgtaggatta gcagcatgcg gtaacaacag cgacagcaaa gattcagcaa ataaagcaga
     6601 cgacacgaca ttgaaagtcg gcgcttcacc gacaccgcac gcagagattt tggaacatgt
     6661 gaaaccatta ttgaaagatg aaggaatcga tcttgaaatc gtcaaattcg atgactatgt
     6721 attaccgaac caatctttgg aagaaggcga cattgatgcc aattacttcc agcatattcc
     6781 ttatttgaac aaagaaatca aagaaaaagg atatgacttt gtcaatgccg gtgctgtcca
     6841 catcgaacca atgggcttgt actctaaaaa agtcaaagat gtttccgaat taaaagatgg
     6901 tgcaacaatc attacttcaa attctgaatc agactgggga cgcatcatca caattctaca
     6961 agatgctggc ttagtcaaag tcaaagatgg agtagatctg gaaacagcaa cattcgatga
     7021 tattgaagaa aaccctaaga acttgaagtt caaccatacg atcgacccat cacttttagc
     7081 ttctacgtac caaaatgatg aaggtgacct agttgcaatc aacgcaaact tcgcttacgg
     7141 cgcagggttg aatccattag aagatgccgt attgcttgaa aaggacaact ctccttacgt
     7201 gaatattatt gcgactcgta aaggtgatga agacagtgac aaaatcaaaa aactgattga
     7261 agtgcttcac cgcaaagaag tccaagaatg gatcacagac aaatggggcg gctctgttaa
     7321 accagtaaag gctgatgcaa aataaggtat ggaacaaaaa agatgagaaa taagtctgta
     7381 atggcttatt tctcatcttt tttataccta ttctaattta gaaatcaaaa ttgtttaata
     7441 ataaataaaa gatatttgat tttagtaagg aaggtcattg cgcttcattc tcaattagtc
     7501 taaaatgagt gagaacgaaa gagaatttgg gggtataatg catgtctgtc ttagaaataa
     7561 aaaatctaca tgtgtcgatc gaggaaaaag aaatccttaa aggcgtaaac ctaacaatga
     7621 aaaccggaga aatccatgcc atcatgggac ctaacggcac aggaaaatct accttatctg
     7681 ccgctatcat gggcaatcca aactatgaag taacagaagg cgaaattttg tttgacggga
     7741 aaaatgtttt agacttggaa gtagatgaac gtgcgcgact tggcttattt ttagctatgc
     7801 aatatccaag tgagatacca ggtatcacga atgcggaatt catgcgtgca gcgatcaatg
     7861 cgaaacgtga tgaaaacgac aaaatttctg ttatggcatt tttgaaaaag ttagatgaaa
     7921 aaatggcttt actaaatatg ccagaagaaa tggctgaacg ttatctgaac gaaggttttt
     7981 ctggcggaga aaagaaacgg aatgagatcc tgcaattgtt gatgttagaa cctacatttg
     8041 caattttaga cgaaatcgat tcaggtctgg atatcgatgc tttgaaagtc gttgctaaag
     8101 gagtaaatga aatgcgcgga gacaatttcg gtgcattgat catcacccac tatcaacgat
     8161 tattgaacta tatcacacct gatgtcgttc acatcatgat ggaaggccga gtagtcatga
     8221 cagggaatgc tgacctagct aaacgtctgg aagcagaagg ctacgctggt atcagtaaag
     8281 aattaggaat cgactataaa gaagaagaag cgtaaggggg agcaagaatg aaagaaaaaa
     8341 actggctcga ttatcttgac gcggtaaatg atttttcttt aagtaaaggc gaacctgatt
     8401 ggatgagaac cttccgtcaa gacgcactag cgaaagcaga tgaactgcca ttgccgcata
     8461 tcgatcgggt gaaattccat cgctggtcgt tatttgatgt gaaagaaaca caaaccatca
     8521 gtgaaacagg cacgattccg gcatttgatg caatgaaaga caatcctgtg cttgtccaac
     8581 aaggttcatg gacgattttt gaacaactgc ctgtggaatt agcagaaaaa ggagtcattt
     8641 ttaccgactt gttcactgca atgatcgaat atccagaact agtccaagaa tattatatga
     8701 aaaaagcagt aaacatgaac gaagaccaat tgactgcact ccatgtagct tttatgaaca
     8761 gcggtatttt cctgtatgtg cctaaaaatg tcgtgatcga tgaaccactc gagtccttat
     8821 tcattcaaga tggcgcatcc gatgagcact tcttcaagca tgtgttgatc gtggcagatg
     8881 aacatagtga attttcttat ctggaacgtt tccagacaac caaagaacaa gtagcaaaat
     8941 catcaggtaa tatcatcgtg gaagtcatcg ctaaagctgg ttcaaaaatc aaatattcag
     9001 ccgtagatca attaggagaa aatattactt cttatatgaa tcgccgtggg cacattttac
     9061 gagatgcttc tgtcgactgg gcaattggtg tcatgaatga cggtcatgtg atcgctgact
     9121 ttgactcaga tttagcagga gaaggtgcac acgcagaagt caaaatcgtg gcaatcagct
     9181 cgggcagaca aatccaagga atcgatacac gagtaaccaa taaagcccct catacgatcg
     9241 ggcatatttt gcaacacgga gtgatccgag aaaaaggaac attgaccttt aatggtatcg
     9301 gccacatctt gaaaggggca aaaggtgcag atgcccaaca agaaagtcgt gtcttgatgc
     9361 tttctgataa agcacgtggt gatgcgaatc ctattctttt gatcgatgaa aacgaagtaa
     9421 ctgctggaca tgctgccagt gtaggacgag ttgatccaga agaaatgtac tatctgatga
     9481 gtagaggatt gcataaagaa gaagcagagc gcttagtgat tcgaggattc ctcggttctg
     9541 tcttaacagc aatccctgta gaacaagttc ggaaagaatt agtcgaagta atcgaaggga
     9601 agttgaatgg atgatcgatg ctaaaaagct acgcaatgat tttcctatct tatttcaaga
     9661 cgtcaatgat gaacctttag tttatctgga taatgcagcg acgacccaaa agccaaaaca
     9721 agtactccag gcattagcgt actattacga acacgataac gccaatgttc atcgcggtgt
     9781 ccatacgtta gcagaacgcg cgacccatga ttatgaacaa gcaagagaaa aagtacgggc
     9841 gttcatccat gcaaaagaaa cagcagaagt gctgtttact cgtggtacga cgacaagctt
     9901 gaattgggta gccagaacct tcggcgaccg ctatatcaaa gcaggagacg agatagtgct
     9961 ctcttacatg gaacatcatt ctaatgttat cccgtggcag cagttggcaa aacgaacagg
    10021 tgctgtcttg aaatatatcg aactaacaga agaaggcttc ctggatatgg aggatgcagc
    10081 gaaaaagatt acggacaaaa ccaaaatcgt ctccattgct catgtatcca atgtcttagg
    10141 tgtcttcaat cctgttcaag aattagctga acttgtccat gaaaacggcg gggtcatcgt
    10201 agtagatggt gctcaatctg ccccgcacat ggccattgat gtccaagcac tagactgtga
    10261 tttctttgct ttcagcggac acaaaatgtg cggaccaaca ggtattggtg ttttatatgg
    10321 taaacgaaaa tggttagaag aaatggaacc tgttgaattt ggtggcgaaa tgatcgattt
    10381 tgtcgaatta tacgacagta catggaaaga actaccttgg aaattcgaag cagggacacc
    10441 aaatatcgcc ggcgctatcg cattaggcca tgcaatcgat tatttgcaaa aactcggtat
    10501 ggacaatatc catcgatatg aagaagaact agccgcttat gtgttgccaa aattacaagc
    10561 aattgatgga ttgactgttt atggtccaca agacccgaat tttcggacag gagtcgttgc
    10621 attcaatttg gatgggttac atccccatga tgtcgcgaca gctttagaca tggaaggggt
    10681 agccgtcaga gcaggtcatc attgtgcgca accgctattg aagtaccttg aagtatcagc
    10741 gactgctcgc gcgagctttt atttctacaa cacaacgcaa gacgccgacc gtttagttga
    10801 agcaatcatg gcaacaaagg agtttttcca acatgggact atctaaatta gacaatttat
    10861 accgtcaagt gatcttggat cattcttccc atccgcatca tcgtggaagc ttgactgact
    10921 cgacaagcaa gatcgaattg aacaacccca catgtggaga tgtgatcgaa ttgcaagtcg
    10981 atgtaaaaga cggaatcatc aaaaatatcg cctttgacgg cagtggctgc tccatcagta
    11041 cggcaagtgc ctcgatgatg acagacgccg tcatcggaaa atcaatagaa gaagcagaac
    11101 atttaactgt agactttcta cagcttgtcc aaggaaaaga agtcaaagat cccgaccaat
    11161 taggcgatgc tgctatgctt ggtggtgtag ctaaatttcc cgctcggatc aaatgtgcga
    11221 cacttgcctg gaaagcacta ggaaaagcaa tggaaaacga tggtaccgca gctttccatc
    11281 attaccacaa ggaagaggag tgagaacatg ggcgtaccag aattagaaga atataaattc
    11341 gggtttcacg atgatgtcga accggttttc agtacaggag aaggcttgac agaagaagtg
    11401 atccgtgaga tgtcaagaat caaatgcgaa ccagaatgga tgcttgaatt ccgtctgaaa
    11461 tctctagaaa catttaacaa aatgccaatg caaacatggg gccccgacct ttcagacatc
    11521 gatttcgatg ccatcaaata ttaccaaaaa ccaagtgaca aacccgctcg tgactgggaa
    11581 gacgtaccag aaaaaatcaa agatacattt gaaaagattg gtataccaga agctgaacga
    11641 gcttatctag ccggtgcttc cgcacaatat gaatcagaag tcgtgtacca taatatgaaa
    11701 gatgaattcg aaaagttagg aatcgtcttt actgacactg actctgcttt gaaagaatac
    11761 cctgaattat tcaaagagta cttttcaaaa cttgtaccgc caaccgacaa caaattagca
    11821 gcgctgaatt cagccgtatg gtcaggtggg acctttattt acgtgccaaa aggcgtcaaa
    11881 gtcgatgttc cattacaaac gtacttccgg atcaatgcgg aaaacacggg gcaattcgaa
    11941 cgtacgctga tcattgttga cgaaggagca agcatccact atgtcgaagg ttgtacggca
    12001 cctacttatt caagtaacag cctgcatgcc gccatcgtag aaatctttac aagaaaagat
    12061 gcgtattgcc gttacacaac gatccaaaac tggtcagaca atgtgtacaa cttagtaacc
    12121 aaacgagcaa aagcatacga aggcgcaacc gttgaatgga tcgacggaaa cctaggtgca
    12181 aaaacaacga tgaaataccc aagtgtttac ttagatggaa aaggtgcacg aggcaccatg
    12241 ctctccatcg cctttgcagg agcaaaccaa atccaagata cgggtgcaaa aatgatccac
    12301 aatgcaccaa atacatctag ctctatcgtc tctaaatcaa tttcaaaaga cggcggagaa
    12361 gtaaactatc gaggacaagt aacctttgcc aaaaacagtg cgggttcgat ctctcatatc
    12421 gaatgtgaca cgatcatcat ggacgaatgg tcgaaatccg atacgatccc attcaatgag
    12481 atccacaaca gccaagtctc tttagaacac gaagccaaag tctcaaaaat ctcagaagaa
    12541 caactctact atctgatgag ccgaggcctg accgaatctg aagcaactga aatgatcgtc
    12601 atgggctttg ttgaaccatt caccaaagaa cttccaatgg aatatgcagt cgaactcaat
    12661 cgattgatca gttatgagat ggaagggtct gtaggttaat aactatttca ttgctcgaaa
    12721 cgttgata
//
LOCUS       DAFENC010000063        12546 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.065, whole genome shotgun sequence.
ACCESSION   DAFENC010000063
VERSION     DAFENC010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12546
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.065"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..263
                     /locus_tag="LP493_002480"
     CDS             <1..263
                     /locus_tag="LP493_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134592.1"
                     /translation="AQLWNMMYFNIGPKVHEELDFCFATDPIEKVKEVKILHNAGVTT
                     NDEDLFFKGRYVTSTPFDEDLSFVNKKKCSYAYVKAIKAVVR"
     gene            260..571
                     /locus_tag="LP493_002481"
     CDS             260..571
                     /locus_tag="LP493_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134593.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            561..914
                     /locus_tag="LP493_002482"
     CDS             561..914
                     /locus_tag="LP493_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBL2134594.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            904..1305
                     /locus_tag="LP493_002483"
     CDS             904..1305
                     /locus_tag="LP493_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134595.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            1298..1702
                     /locus_tag="LP493_002484"
     CDS             1298..1702
                     /locus_tag="LP493_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134596.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            1714..2319
                     /locus_tag="LP493_002485"
     CDS             1714..2319
                     /locus_tag="LP493_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL2134597.1"
                     /translation="MAKTTTVTTFDNISIKRISFNFKNATNAISTDCNGQLDGETEMQ
                     RIVKKCGSTEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDERIKSGIYSYGPDSVG
                     EDFSLAAEIVDDFEEKNKLIGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFGK
                     FYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            2339..2701
                     /locus_tag="LP493_002486"
     CDS             2339..2701
                     /locus_tag="LP493_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134598.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            2704..2886
                     /locus_tag="LP493_002487"
     CDS             2704..2886
                     /locus_tag="LP493_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134599.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            2903..6322
                     /locus_tag="LP493_002488"
     CDS             2903..6322
                     /locus_tag="LP493_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBL2134600.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASESEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLTKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDYAVAIGGLTAAFTLLMPIIVGFMALGGPTTL
                     IIGAVITVIAGVIAIIKNWGAITDWFKGIWSKFTDWLGGTWESIKEGASSVWDGVKET
                     WSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQETWQAFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWVSIAWNGIVTTFHTIFDPVVAWWNGIWTAISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISSIFDNLNISIPHIPLPHFKLSGEF
                     NPLKGKIPTLGVDWYAKGSVFNSPNIIGVGEAGPEAVLPLKRSVLQEIGDRILSSTSV
                     SSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKVQNDNASAWR"
     gene            6373..7110
                     /locus_tag="LP493_002489"
     CDS             6373..7110
                     /locus_tag="LP493_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL2134601.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVVGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINYFNCTGLSKIQIYRNGLR"
     gene            7120..9411
                     /locus_tag="LP493_002490"
     CDS             7120..9411
                     /locus_tag="LP493_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBL2134602.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYPISGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITASQAWQNAKTLAKPVIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKRLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLLNDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGADYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDNGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            9435..11516
                     /locus_tag="LP493_002491"
     CDS             9435..11516
                     /locus_tag="LP493_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134603.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDNVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAEIKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSIDFGNYDYSGNPNLMSKLKSSDFN
                     VGYHGSLTSDNEKLHFTSDGTGSIIMFTRINTPQLASGKTYTLSAKVRFDEGTTGAID
                     KLRLVYRTSPGEKILLEANSTNITTDDVGKEITIKGTANVNYQITNLDRFYMSISFVD
                     RDKINGGFKLYDIKIEEGSTATPYQPNLLDGPYWLGKVPLGENIADHTVKFPIESGDH
                     QIYQGYTEEELMIGQTYTITLKGTKPASQTFVAYNHWTARLGELKPVDGLTDVWSLTF
                     TPTNVVASSPKLFRVYQYPQSTVGACRIDWLKIEKGDTRTPNISEYKYRGTGMRDSNN
                     PKDYVWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSEINSQLTASINEVDTTAKD
                     AQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSAKLYREGKTVSIYFVALN
                     GKSSGGNDSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYG
                     SDYTFAITYTI"
     gene            11533..11682
                     /locus_tag="LP493_002492"
     CDS             11533..11682
                     /locus_tag="LP493_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134604.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPIPNWKPKFNY
                     WEGNK"
     gene            11679..12125
                     /locus_tag="LP493_002493"
     CDS             11679..12125
                     /locus_tag="LP493_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134605.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            12127..12264
                     /locus_tag="LP493_002494"
     CDS             12127..12264
                     /locus_tag="LP493_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HBL2134606.1"
                     /translation="MFSFSDVKMMYDWGCFTNEQVMVFVPLCITEEKADKIISKEESA
                     S"
     gene            12302..>12546
                     /locus_tag="LP493_002495"
     CDS             12302..>12546
                     /locus_tag="LP493_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134607.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLV"
BASE COUNT         4427 a         1915 c         2632 g         3572 t
ORIGIN      
        1 gggcacagct ttggaacatg atgtatttca atattggtcc taaagttcac gaggaattag
       61 acttttgttt tgctactgat ccaatagaaa aagttaaaga agtaaaaatc ttacacaatg
      121 ctggagtaac aacaaacgat gaagatttat ttttcaaagg gagatacgtg acttctacgc
      181 cttttgatga agatttatca tttgtaaaca agaaaaaatg ctcttacgca tatgttaaag
      241 caattaaggc ggtggttaga tgacgcctga acaagtgact gaagaattgc taatagctgt
      301 gaaggataat atttacgtta cctggaacga agaagatgag tcaattaaaa agatgatagc
      361 taaaaatgct gtttatcttc aaagtaaagt gagtacaaca ctttcttttt ctcctgaaag
      421 cttagaatac ggattgctaa tcgaaagatg tagatacgac tggaatcgtg ctttagatga
      481 gtttgaacaa aatttcgcta gtgagttatt aggtttcatt caacattatg cgctacaaga
      541 atatattgca ggtgatgtga atggcgaata atcgtagact cgaagaaaca ttcaacgatg
      601 gttggttaaa gattttgacg caaactacca aaagaaatga actaggaaaa aagattggtg
      661 tagaagatac agaaatcact tctttaaaat ttagaaatct ttccatgaga gatagtgata
      721 taacagctat ggatgcgatg ggatcgaaat taactaagaa agtaaagact ccatttcatc
      781 caatcgccaa gaaatttaat aaagatcaat attttatcgt aatcgatagt atgcgttaca
      841 acgttatcta tgccgattac gataattttt atatctattt ttatcttgaa agtgtgggtg
      901 aatatggtga ttgataattc taaagaaaaa gaacgtttaa ataagcaaat ttctgctatc
      961 aaaacttcct tagaagagca ttttggcctc aaactctttc aagactccgt aggcgaggat
     1021 gagctacctg atgattttaa ttacttcatt ctcgaaacag gagaaataga aatgatcact
     1081 gagccaaaat atagcgtggg tcaaaatcta tatctaactt tctattcaga aaatagagaa
     1141 gatttaacag gagattcact agatattatt tcattgattc aaaatcgttc gattcgtttt
     1201 cagagaatgg atcccaatca tttaaaacta gagaaccaag atcgctatat cgatcaattg
     1261 gtatttacgt ttagacgatt attgaagagt gattgtcatg gctaaaaata gttgggagct
     1321 aaaaataaat ggacatgatg aacttcttgt gcggatggaa cgctattcaa gcgagagcga
     1381 acgactgatt aacgaagcat tgaaatcaaa aggttcggct attgcagtgg ataggattac
     1441 agaaaaaatt cctgtttctg aagcagattt aagaagaggg caccaacacg caaaaaatag
     1501 tcgtccactt aagactcaat acattaattt gggtttcatc attagaccta caagaaaatt
     1561 tgagtattta aaatatcctg atttggggat aggtacttct aaaagaaatc agccggacga
     1621 atttatgaga agaggattag gtcttgcact tgatccaatt acagaacttc tgattcgtca
     1681 attcgataaa ttaaataaat aggaggaaca acaatggcta aaacaacaac agtaacaact
     1741 tttgacaata taagtattaa aagaatttct tttaatttta agaatgcaac aaatgcaatt
     1801 tcaactgatt gtaatggaca attagatggc gaaacagaaa tgcagagaat tgtaaaaaaa
     1861 tgcggttcaa cagaagtaaa atcgaaatct aaaccaatca atatgacggt aacaattact
     1921 gcacatgtac cgatggaagt ttatcgacgc ttcaatgggt tgaaacaaga tgaacgtatt
     1981 aaatcgggaa tttactctta tggtcctgat tccgtagggg aagatttctc tcttgctgca
     2041 gagatcgtgg atgatttcga agaaaaaaat aagctgattg gtatgttagc atgcacttcg
     2101 aatacaggat taacattctc tattgaaaat ggtgcggatg aagtagctgc gttagaacta
     2161 gaaacaaaag ttatgcaaga tgaatttggt aaattttatc atgaagcaat tgttgcagaa
     2221 cttgaagaag acttaacaga tcaatggatg acgaatctat ctgctgatgt gattaaaaaa
     2281 acttcagttg tgacaactac ggccactcaa tcacagtaaa aaaaacggag gtagcgaaat
     2341 gaacgaagat tactcaaaaa ttgaactaaa cgatggaaca attttgaatt tagaacctaa
     2401 actgaatatc aagaaattat tgatgatcaa tagagatttt aacacagacg agtttgcaaa
     2461 aatgactgtg ggaaaaggat ccatggatat ttctgttatt caaggtgcaa aggctgtgta
     2521 tattgcttac cgccaagcga acatgactga ttatatttca ttcgatgaat ttatcgataa
     2581 atgggatttt gatatggcta ctgccagcta tatttatcaa ttgatgatgt tcaaacaagc
     2641 acgcgatgct tatcaaaaag aatttgaaaa agcaaataag gaaaaaaagc ttcaaaagta
     2701 aaaatgccaa agctcttagt tgaaacgtgg gtcgatgtct attcgatgtt gaccgacgtt
     2761 ttttctatgc cttcagattt ggttttaagc gatatctgtt tagatgacat tttgcaaatg
     2821 gcttacaaca agagtgctta tgaaggatgg aaaaactatg caataaacca atcccagaaa
     2881 aactaaagaa aggaggtaaa aaatggctaa aaagagaaca gaagcagaag taacattcat
     2941 agctaacgat gacggattga aatctacgtt aaaagaaatc agtgctgaat taactaaaaa
     3001 tagagcagaa ttaaaactag aacaagctca attacaacag actggttctg aatcagacaa
     3061 gttaggaagt aaattatctt ctttagaaaa gcagtatgaa ttacaaagtc aaaaagttga
     3121 agtaactagc caacgtttag ccaatgccaa aaaatattat ggagaaaatt ccaccgaagt
     3181 tcagaaactt gagagagaac tgattaacca acaaacagcg caacaacgtt tgtcaaacga
     3241 aattgataaa acgagtaatg cactagctca agcaaaaggc gaaatacaga cgtacgagtc
     3301 tacaatgcaa cagttggata gtgaacaaaa aaatgttcaa gctagtgctt ctctgattga
     3361 atccgaatac aaaaaatggc aagcaactgc tggtcaatca gcttctgaat ccgagaaatt
     3421 agcgaaagcc caagaatatg tttctcaaca atctgaaaat gcagagaaaa cgatagatat
     3481 cctgagacga cagttagaag ctacacagtc tgagtttggc gctacatcca cagaagcaat
     3541 gcagatggag gcgaagctta atgatgctga acgtgaattt gaagagttag gacaagctgc
     3601 taaaaatgta gatacaacta acttggacga tatcggaagc aaaatagata tgaataatct
     3661 aatggaagct tctgacgttt taagcgacat tggcgataag cttacagaat tagggaaaca
     3721 agcagtggac tctgctaata gtgtaggtag ttcccagagt aaaatacaag ctaattttgg
     3781 tttgactaaa caagaggctg aagaattaac gaatgtagcc agagacattt attataaagg
     3841 ttttggagaa tcgttagatc agtccacaga tgcattgatt ttggtaaagc gtaatttagg
     3901 cgatttaaat aatcaagatt tacaaaatat cacggaacaa gctatggtcc tagaaaacac
     3961 catgggcgct gatatggatg aaacgttacg tggtgtaaat ggcttaatgg tcaatttcgg
     4021 cttgagcgct caagatgcaa tggatttaat ggtttcgggt actcaaaacg gtttagataa
     4081 aacgcacgaa ttaggcgaca atatggcaga atatagccaa ttatggagtc aaatgggata
     4141 ttcagctgat gaaacgttcg gaatgcttca aaatggttta gatgcgggtg cttataacct
     4201 tgataaagtc aatgacttag ttaaggaaat gggaatatcg ttaacagatg gtcgatttga
     4261 gcaaaacatg gatatgttta gtgaaagtac tagaaaagct tttgaagagt ggaaaaatgg
     4321 cggaggaaca caaaaagacg ttattaattc catgattcaa gattttagca atatggatgg
     4381 tcaatacgac caattaaata aagcttctac aatttggtct gcacttggcg aagataacgc
     4441 gatgaaagtt gtccaatctt tgactgatgt taaccataca tttgatgatg ttagtggatc
     4501 tgcacaaaaa atgaatgaag attctactac tccgttacaa gaattaaacg gaaaaatagc
     4561 tgaattaaag gattcattag ctcctatagg caacacaatc atagatgcac tcgaaccagt
     4621 aattgatttt ctaggaaaga tggctgatgc gtttaataat cttccacaac cagtacagga
     4681 ttatgccgta gcgattggcg gattgactgc tgcatttact ttattaatgc caataatagt
     4741 tggcttcatg gctctaggtg gtcctactac attaataata ggagcagtta ttactgttat
     4801 tgctggagtt atagcaatta taaaaaactg gggcgcaatt actgactggt ttaagggaat
     4861 atggagtaaa ttcactgatt ggttgggtgg tacttgggaa agtataaaag aaggtgcctc
     4921 atcagtttgg gatggagtta aagaaacctg gtctggattt gtagattggg ttcaagatat
     4981 ttggcaagga gtttctgatt ggtttggaga gctatggagc ggattagttg aaggagcttc
     5041 caacatctgg caaggagtcc aagagacttg gcaagcattc gttgattggg tttcaaatat
     5101 ttggaacgga gtcaaagaag tatggtcgat tatttgggca gacattgtag gaattgttca
     5161 aataccatgg accttaataa cgtcattgat tcaagccggt attaatatta tcgtgggtat
     5221 ttttgatgta gctggacagt tattaggcgc agcttggcaa gctgtttgga cacctatttc
     5281 tgatttcctt aaaaacactt gggatactat gacacaatgg gtaagcatcg cttggaatgg
     5341 aattgtaact acattccata ctatatttga tccagtagtg gcatggtgga atggtatatg
     5401 gacagctatt agtactacgg cttcaaatat ttggaattca attagtgcaa cagcttctag
     5461 tatttggaac agtatcaaga atacaatcac tagcttggta caagcagctg ctacagtaat
     5521 tcaaaatatt tggtcaactg tatctagttg gttaggtgga atttggaatt caatcagctc
     5581 tacagcatca aatatctgga atagcgtgac tagtagtata agcaatgcta taaacgcagc
     5641 taaaagtgcc attcaaagtg tttggaatag tatatcttcg tggatcagcg gaatttggaa
     5701 cggtatcaaa aacactgctt tgaatctttg gaatggaatt acaagcacta ttagctctaa
     5761 agtaaacgat ggaaaaaatg caatttcaag cggttggtcc aatctaacag gtattgtttc
     5821 cgacatattc aataatgtta aaagtacaat tgctaacatt tgggaaggta tcaaaaagac
     5881 tgttagcgct ccaattgatt ggatcagaga taaaatcagt agtatctttg ataatttgaa
     5941 tatttctata ccacatattc cgttaccaca ttttaaattg agcggagaat tcaatccatt
     6001 gaaggggaaa atcccaacgt tgggtgttga ttggtatgcg aaaggtagtg tgtttaattc
     6061 tccgaatatt atcggtgtcg gcgaagcagg acctgaagca gttttacctt tgaaaagatc
     6121 tgtgctgcaa gaaattggtg atcgtatctt gagtagcaca tcagtttcat ctagggcaca
     6181 aacgattcaa cctgtgaata actacgaatt caatttcaca attgatggta acgcagatga
     6241 ggttactatg aagcaaacaa ctcaacaaat cattgatagc attacaaaag ttcaaaatga
     6301 taatgcttcg gcatggcgtt aaacaggaga gtatttctcc tgttttttta gtattaaaaa
     6361 ggatgtgaaa aaatgactga ttgtatacat tctataatcg atggatttcc tgattatttg
     6421 cataaattgg ctttagctga aagaccaacc ataccttctc caaaaagaca gagagttgaa
     6481 acttctgttt taggaaggtt aggtggctta gtacaagatt actcgtttga agacatgtcg
     6541 tttacattgc actataacta tttagaggat gtggaagacc atcaagcgtt caagcaatcg
     6601 ttttatatca tgcgtcattg gttaaattat gcaaagaaat tagaattctc tgatgatccc
     6661 aacgtctatt atgttatcca gactatcgat attggggatg cagaaaacga tattgttgaa
     6721 tggggagagt tcgatgtaaa tattactgcg aaaccattcg caagagttca agaagatgta
     6781 cctataaccg tagataaacc acagtcattt aacttgctga ataatagttt agaagaaagt
     6841 tttccaaaga ttatcatcac tccttcagct acttcatgcc agttcatctt aaatgattat
     6901 gtgtttagtt ttgaaggctt agtagtagga actgacgtag tcattgatag tgatttgatg
     6961 ctttgctacg aagagcaatc ggacggagat attttagatc ggtccaacaa aatgaagacc
     7021 atgcaatatc cgacattgca agtggatatt aattatttta attgtactgg tttgagcaaa
     7081 atacaaattt atcgtaatgg gttaaggtag gtgaaataga tgatcgataa tttaataact
     7141 atttacgata aaaacgacgc gaataattta gctgaacatt tatatgatac gcaaggttta
     7201 ggcgctttgt cagactggtt aacagctact gttagcaata aattaaacgg agccgagata
     7261 tttcagggta cttatccaat aagcggaact aatgcagatt tgattgtaga aggacgtatt
     7321 attcagtgtt atgtagatga aaatcgagca aaacagcgtc tacggattta ttatgcaaag
     7381 acttctgtaa taggcaatac gatagaagta aaagctgaac ctattttcaa tgatataaga
     7441 aaatcggtgt tgaataaata tgacagtgga acagaaaaga tcactgctag tcaggcatgg
     7501 caaaacgcaa aaactttagc gaaaccagtt attccttcac agttttcttt ctcgtcatta
     7561 gtagatacgc ttgctaatgt gaagatagaa aaggcgaatt ttttagaatt ctttggtgga
     7621 aaagagggat ctattctaga tcgatttcat ggggaatttc taaaagataa taacacatta
     7681 cgtcatgaaa aaaggctagg cacggatcat aaaatcaaag cgatttatac taaaaactta
     7741 actggtcttg acttagagat tgatgctcaa agtgttttag ttggagttta tccattcatt
     7801 agcagctctt cagaaggaga agacgagatc actctaccag aagaagttat tttcacggat
     7861 tacgtggatg attatcctgc tggatatgtt tcttttgttg attttaaaga caaagcgact
     7921 gatgtagcca cattaaggga agctgctaaa gactggttga aaacaaacat agataaacaa
     7981 aaaccacaag tgagtggttc gattgaatta gtaccattga ggcatcaaag aggctatgaa
     8041 aaatttgttg atctagaaaa agtttcgatg ggtgacggag tagatgtgta tcatccacag
     8101 ttaaaagtga atatgtcagc gagaattgtg gaatatacgt ttaatgttct aaccaattca
     8161 tacgataaat tagttgtagg aaacgtcaaa acaaacttct tagaaaacac agagaataat
     8221 gtcagcaatt tgattaatga tgccattgat caattgaaaa acggtggcga aatcagtgat
     8281 ttactcaatg atattgtaga tcatcaaact gatatgatta ctggtcaaaa tggtggttat
     8341 gttttattag atcctaaaga agcgcctagt cgtattttga ttatggacac accagataag
     8401 aataccgcaa ggaatgtttt acaaatcaac aatgctggta ttggtttttc taaaactggc
     8461 attaatggaa catatgaaac ggcatggacg ttagatggcg gattcaatgc ctcgtttatt
     8521 acggctggtg aaatagtagg aattactatt agaggtacta cattaattag tgatggtgct
     8581 gattatagaa caagtattgc taatggcaaa atgacttggt actcaaaaaa agttaacaaa
     8641 gatattatgg agctagaagc acgtgattat gtaagtgctg atgccggtat tgtatcatac
     8701 accatgaaaa ctggtggtgg tttcatgatt agaaatccac agggtaactt ggtttttagt
     8761 acgtgggata atggtaataa cagaccgttt ctatcttttg gtgcgcccaa tttcaggtat
     8821 agcaatgcta gttatgtaac ttctggcgac ggtagttctt taagcattaa tggtagtgcg
     8881 ggtaactcat gggaatttaa ggtagctggt aggactatga aatttactag tgatggtatg
     8941 ctaacgttac caggttgttt ttttggttca tgggaagatg ggaaacttgc taggtttgaa
     9001 caatcaacgg tacaagtata taaagatttt actgttagag gtactaaaaa ctcaactgta
     9061 ccaacagaac attatggaca acgactattg aacgcttatg aaactccaga atattatttc
     9121 gctgattatg gggaagccgt tacaggtgac aatggtaaag ttcgtgttga tattgacccc
     9181 atgtttgctg aaacagtaaa tctaagtcgg tatatgacac atgtgacacc tacagaacta
     9241 gttttgtgtg ctgttactca tgaagatatt gaccatttca tcattgaaac tagtaagcca
     9301 aacgtattag ttagatggaa tttagtggca caccgtctag ggtatgaaga tattagatta
     9361 aaagaggata cagcatatga tagcacagtg cttgaccaaa aacgttttta aaacgaagac
     9421 aaggaggtat ataaatggct agcagtttat ataatttggc tttagatttc agcaaagaat
     9481 taaactacac caaagctatt atggctcgtc aaggtgataa agggattacg gtgacggtta
     9541 aaccgtttct aaatggcttg cagatggata cgagtggcgg aacatttact ttaaaaggaa
     9601 caacaccatc taaccgttac gtagataatg ttgcaactag tgtaactagt gaagaagtca
     9661 cgttttctct tgatggcaca tttatgagtg aagcaggata ttataaacac tgctacgtag
     9721 aatatagaaa agacaatcaa attttaacaa cgcaagatat catttttttc tcactaggag
     9781 tgtctgacat ttcgcaaggc caagccgatg aatatgtttc gcaattagaa gagttgattc
     9841 gaaagtacaa cgaaactttt gatgctttta tggctgaaat caaaggtaga gtggatagct
     9901 taaatcaaca gattactgat ttaactggtc aagctaaaac gctacaagac aagttagatg
     9961 ctctgaaaga agaaatttct aagttaggta acttacaagt gatgtacagt aacagcatcg
    10021 acttcgggaa ttatgattat agtgggaatc cgaatttaat gtccaaacta aaatcgagcg
    10081 attttaacgt tggttaccac gggtcactaa cttcggataa cgaaaagcta cattttactt
    10141 ctgatggtac aggaagcatt attatgttta cgcgtattaa tacacctcag cttgctagtg
    10201 ggaaaaccta tactctgagt gcgaaagttc gatttgatga aggaactaca ggagctattg
    10261 ataaattacg tttggtgtat cgtacatcac caggagaaaa gatattattg gaagcaaata
    10321 gtacaaatat tacaacagat gatgtaggga aagaaataac aatcaaaggt acagctaacg
    10381 ttaattatca aatcacaaat ttagatcgat tttatatgag tattagcttt gttgacaggg
    10441 ataaaataaa tggcggattt aagttgtacg acatcaaaat cgaagaaggc tcaacagcca
    10501 ccccatatca gccaaactta ctagatggcc cttactggtt aggtaaagtt cctttaggcg
    10561 agaatattgc cgatcataca gttaagttcc caatcgaatc tggcgaccac caaatatatc
    10621 aaggttacac agaagaagag cttatgatag gtcaaacgta tactatcacg cttaaaggaa
    10681 caaaacccgc aagtcaaacc tttgtagcgt ataatcattg gactgctcgt ttaggagaac
    10741 taaagccagt tgatgggttg acagacgtat ggtctctaac attcacacca acgaatgttg
    10801 tggcgagttc acctaaactt tttcgtgttt atcagtatcc acaatcaaca gtaggcgcat
    10861 gccggatcga ctggctcaag attgaaaaag gcgacacacg aaccccgaat attagtgagt
    10921 ataaatatcg tggtactggt atgcgtgatt caaacaatcc aaaagattat gtttgggatc
    10981 tagcaccaga atatgtcgaa gataacttgg ccacagatat taaaatttct gaaattactg
    11041 gtaaagcaaa caattatacc gatgggaaag tatcggagat taattcgcag ttgactgctt
    11101 caattaatga agtagacacc acagctaagg atgctcaaac aaaagcgaat gctaatgcga
    11161 ctgctataga tgaattagac aataagatcg atgaacgcat taatgataca gctactacca
    11221 cattaacagt tacaaacggg aataccggat cagcaaagct ttatcgtgaa ggaaaaacag
    11281 tttctatata ttttgtggct ttaaacggaa aaagcagtgg tggaaatgat tcaacgatac
    11341 taacaattcc agaaggctat cggccaccaa ttagttttga gcaactggtt ggctcgatag
    11401 accgttctac tttgaacagt gctcagttat ctattggtgc agatggagcc attaaatggc
    11461 gaagaaactc aagttatgga tcggattata cctttgcaat tacttacacg atttagaaaa
    11521 gcgtgaatcg atatgaaggc agcatataga ccaattgaac cttacggatt cgagcaaatc
    11581 attgtgaatg atgaagaaca tttaccggaa gaatgcacag aagtcgaacc accgattcca
    11641 aattggaaac cgaaattcaa ttactgggag ggaaataaat gaaaaacatt tggaaatatg
    11701 gacgtactgg cggagagtac gcaggaaaag tattggacga catgcttgta tccgttcctt
    11761 acacagatca gccaccgctt gaaggaattc gtgctgatgg cgaaccgtta acaatcgctg
    11821 atcaaatgtt tgatcctaaa ttgaatcaat ggattatttt agcgaacgca ctagatcaca
    11881 acgatttaaa caatctcaaa gcaatgtatg agtcgttaga aaatgagaac ggcgatttaa
    11941 aacagatcaa tgccaaactc atgctaagcg atgtagcaat taaacaggaa aatactgcat
    12001 tgaaagaaaa agcggatagt ttagcacaaa tcaattcaaa aatgatgctt gcttcgttac
    12061 aaaatagcaa agacatttca gaaattaaag agcaactaaa tccagcttca aagggaggtg
    12121 agtagtatgt ttagttttag cgatgtgaaa atgatgtatg attggggctg tttcactaac
    12181 gaacaagtaa tggttttcgt tccgttgtgc attactgaag aaaaagcaga taaaatcatt
    12241 agcaaagaag agagcgcatc ttaattgatg tgctttttat tttgattcaa ggagttgtca
    12301 catgattaat ttaggggaat ggggagcgat agcaggatca ataaccgcta tcgtttcttt
    12361 gattttatta gtaataaaac caattactgc atctttctcg aagattactg agactctttc
    12421 aaaagtaagt cacaatttag atttgctgac taaagattta gaatcgagca aatcagatcg
    12481 attgatgatt catgaagaac taaagaaaca cgatgaaaga ttagatacac atgcagaaaa
    12541 attggt
//
LOCUS       DAFENC010000064        12494 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.066, whole genome shotgun sequence.
ACCESSION   DAFENC010000064
VERSION     DAFENC010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.066"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            158..730
                     /locus_tag="LP493_002496"
     CDS             158..730
                     /locus_tag="LP493_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003706982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HBL2134608.1"
                     /translation="MTENKATQERTPQERLQEEQEHKEHVHHTKINAAAIADHLLGNM
                     HTLHVKLHQYHWYVKGANFFTLHEKFEELYNENEKWFDKLAERLITSGHKPASTTVEF
                     EKYSMLSEDAVNKYAKAEDMVENIIEDFRSTRDLTIRAIRLAQDEGDDALEDTLIAFK
                     NDLDKNIWMLQAFIGKEALEDDDALDEDED"
     gene            875..1579
                     /locus_tag="LP493_002497"
     CDS             875..1579
                     /locus_tag="LP493_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011476586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBL2134609.1"
                     /translation="MTKHTHHEIGDHAACIRLVPIFNHLEDSAMNYIAEKAHTKQYQK
                     GEFLFRSQEKEDTLYIINRGKIRIYRLADSGKEQLVRILNPGDFTGEWTLFNPDAVHE
                     EYAEATRDTVVCMIQQKDVQDFLEQYPAISLKLLAEMSKRLESSERQTTQVAVESVIT
                     RLVLFLAENVEPEMGNSPTITLPMAKKDIASYLGTTPETISRKFGELEDEGLIQQLSG
                     KRIKIQDLDDLLLYSE"
     gene            1807..2145
                     /locus_tag="LP493_002498"
     CDS             1807..2145
                     /locus_tag="LP493_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134610.1"
                     /translation="MHCFWVIVAITLSAAGAFFVVPFTKNTIGGEAKTSNVVEADRLA
                     MEKEEEVVKGAGVIGHGKVAYYEASDQGDKSVFTVWFPWSLAGILFSITMTRMTRKIE
                     EMEQIEWDSY"
     gene            2130..2984
                     /locus_tag="LP493_002499"
     CDS             2130..2984
                     /locus_tag="LP493_002499"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBL2134611.1"
                     /translation="MGFVLGVLNPHVVEIGSVVIHWYGVIIAAGILAALQLSTKEAKK
                     KGLEEDTIIDMALWAIPIGLLGARLYYVLFELGYYLQNPGQILAIWNGGIAIYGGLIA
                     GGGTLYWYAKKKGTSLALVLDILAPNVLLAQSIGRWGNFMNQEAHGGPVTRQFLENLY
                     LPEFIIEQMNMNGTYYHPTFLYESLWSLLGFVLIVTIRNRKQLLRQGEVALSYVLWYS
                     VGRFFIEGMRTDSLWIGEWIRVSQALSLALFIGAIVVWFIRRQDYPPISYYSDGNKGQ
                     KKTIKMVN"
     gene            3131..3364
                     /locus_tag="LP493_002500"
     CDS             3131..3364
                     /locus_tag="LP493_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HBL2134612.1"
                     /translation="MEKAILQLETLSCPSCMQKIEGAVKSVNGIDKDSIKVLFNSSKV
                     KTNFDSAVTSIEEIQKAIENVGYPVLKAKVKAV"
     gene            3562..5466
                     /locus_tag="LP493_002501"
     CDS             3562..5466
                     /locus_tag="LP493_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBL2134613.1"
                     /translation="MQQYILSKKNVITVISGLLIVLGFFSHFVLENVGLSEWSLIIAS
                     VFGITPIAIQAFQAMKVKVISIDVLVSIAAIGALFIQNYEESAIVTFLFLFGHYLEQR
                     TLNQTRSAIKELTEMAPESALKQMDNGEFEEVEVDDIDEGDILLVKTGAKVPVDGIVL
                     TGEGHINEASITGEAIPVNKLADAEVFAGTILENGTIQIRADRVGEDTTFGKIIELVE
                     EAQDSKSEAERFIDRFSKYYTPAVLVLAIVVWAFSQNIELAITILVLGCPGALVIGVP
                     VSNVAGIGNGARNGVLLKGSEVIQDFSNVDTIVFDKTGTLTVGNPTVAATELYEKDPA
                     ETLGYLASVERESDHPLAKAVLNQIGETNFYPVEGTEVVKGGGIVSSVAGHRVAVGNV
                     ALMEKENVTLSKKVQKDVKRFEQQGNSLVLTAVDGELKVLMGIRDQVRPGVKANLQEL
                     KDLGVKNLVVLSGDNQGTVDVVAGELGLTEAHGYMLPEDKSAYIGKLQQRGQIVAFVG
                     DGVNDSPSLALADIGIAMGSGTDVAIETSDVVLMNSNFSNLPHALGLVKATANNMKQN
                     IVISIGVVLVLLTSVFFSEWMNMSIGMLVHEGSILVVIFNGMRLMKYKLKGRKEQKEV
                     SAPAEKVKIS"
     gene            5776..6138
                     /locus_tag="LP493_002502"
     CDS             5776..6138
                     /locus_tag="LP493_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2134614.1"
                     /translation="MEKVCQVTIVHKEKVNVIKKKLDQKDFSNLLVLGKCFSDSSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVFLKLSENLSMKS"
     gene            6155..6766
                     /locus_tag="LP493_002503"
     CDS             6155..6766
                     /locus_tag="LP493_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HBL2134615.1"
                     /translation="MLQSIFSAIAVYISTSIDYLFILLIIFSQSHTKKGIRHIFWGQY
                     LGTGILVAVSLFAAYVLNFIPQDWIIGLLGLIPIFLGIRVAFVGEEEEEEEEVVEKLE
                     SRGTNRLFWTVALITIASGGDNLGIYIPYFTSLAFSEIIIALIVFAISVAVLCYISYK
                     LAKISFVSETLEKYERIIVPIMFIALGIFIMIENGTIQTLLGF"
     gene            complement(6868..7776)
                     /locus_tag="LP493_002504"
     CDS             complement(6868..7776)
                     /locus_tag="LP493_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBL2134616.1"
                     /translation="MSKSDKDHNHSNQNQPKKNIKIAFFINLIFSISEFFFGFLFNSV
                     SIMSDAVHDLGDSISIGFAWFFQGYSEKKQDERFTFGYNRFSLLGALITGVVLISGSF
                     FMIYRSVPRLIDPQPVNYSGMFWLSLVAIALNGYAAWILSKGTSKNESMLNLHMLEDV
                     LGWIGVLIVSILMNFTEAYRLDPILSILIALYILYKTVPEFFTTMKILLNGSPENVNV
                     KSLADSIKNVPAVKDLSHFHIWSLDGEENALIITVLIDPSDIDKAREIKEEIAEVAHK
                     SSVENHITIEITTSKEELEKGYSHNT"
     gene            complement(7818..8132)
                     /locus_tag="LP493_002505"
     CDS             complement(7818..8132)
                     /locus_tag="LP493_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBL2134617.1"
                     /translation="MDIKTTSPIDKGSILSISKLFKVISDPTRLSVLFLLQKKECSVG
                     NIAISLDMEQSAISHQLKTLKDARLVKSRREGKSMLYSLDDLHVFSILEQVLTHVNEL
                     EK"
     gene            8431..10362
                     /locus_tag="LP493_002506"
     CDS             8431..10362
                     /locus_tag="LP493_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBL2134618.1"
                     /translation="METIQEQQSQEKHNHNHNHDHDHDHGKMPVVLYFVGLALAVIAL
                     FLNEDYQLVQNVLFSIATISAGYHVILLEGLGETIENSKAQKKFIPNSHILMGLAAIG
                     ASLMGNFWEGTLLILIFSGAHFLEDYAEGRSKREITKLLEMNPTTARLILPDGSTKNV
                     DVSELKVGDQLQVLNGDQVPIDGVILSGSTSIDESSITGESIPKEKSKGDGVFGSTIN
                     GTGTFTMKVTKENKDTVFSKILQLVNQNQDNQTKAASIIQKFEPKYVTVVLIAIPLFM
                     LLAPFLLDWTWSQSVYRGLVLLVAASPCALAAATVSATLSTTSNLAKKGVLSKGSSYL
                     SQLADIKAIAFDKTGTLTKGKPEVTNYYFADSVNEENMIDIVVALEKESNHPLADAIL
                     RKFEQKNKLTIEVENQIGKGLTGDYKGRNYRIGKPTSFDDVSDEYSRLNNEWASEGKT
                     VVYVAVDEEVIGLIALMDVPSEYAKETIEYFRKQGIHTTLITGDSEMTGKAVAKQLGI
                     DEVIANVMPEDKSRIIDEQKEKYGVTAMVGDGVNDAPALVNADVGIAMGDGTDVAVEV
                     SDLVLMQNNLSKLVQSHNISSKMNRVIWQNIIFSMAVVAFLIVVSFLGLTDIAISVII
                     HEGSTLVVILNGLRLLKAV"
     gene            10655..11206
                     /locus_tag="LP493_002507"
     CDS             10655..11206
                     /locus_tag="LP493_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL2134619.1"
                     /translation="MGYNVQPLRSQQEINDFLFCLRRNKNAERDVFLFLIGINSGLRM
                     SDIVKLKKKDVITSKNPRIVEQKTGKTRILYLSSLQDLIHGYTAPLDPEAYLFPSTKG
                     GHLEVNTVYQMFQKVAKLLGRDDIGTHTLRKTFGYHYYKKTKDVATLMEIFGHSSEKI
                     TKRYIGINEDEISETLLNFRLGF"
     gene            11519..12061
                     /locus_tag="LP493_002508"
     CDS             11519..12061
                     /locus_tag="LP493_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134620.1"
                     /translation="MSIKETTQITRQLNAIYKAAHLLQEHFVDKKVSFVGEVSTVAII
                     FSTTNFMHLCGIDYRRGTHLFFQDALDRKINLQDIQIKTDGTTFQKLQVIGSLDLLLG
                     KHISIVGRGVYSSLRYDAAIRTRKKILALSLKQNGLIYIPISLLNLSSKEIGPGQKVT
                     GIFSEDLTSGELKMIMEVID"
BASE COUNT         4048 a         2093 c         2609 g         3744 t
ORIGIN      
        1 aatttaatag agaagcctgg cgtctattaa gaaataattt tcttgatgag cgtcaatttt
       61 tttaacggaa atctatccta tactaaattc agtaaagaaa aaggaggaat caaagaaagc
      121 tattttaaac aaaccaaaat tataggagga ataaatcatg actgaaaata aagctactca
      181 agaaagaaca ccccaagaaa gattgcaaga agaacaagaa cacaaggaac atgttcatca
      241 tacgaaaatt aatgcagcgg ccattgcgga tcatctttta ggcaacatgc atacattaca
      301 tgtgaaactg caccaatatc actggtatgt aaaaggagcc aatttcttta cgttgcatga
      361 aaaatttgaa gagttgtata acgaaaatga aaaatggttc gacaaacttg cggagcgtct
      421 aattacttct gggcataaac ctgcttcgac aacggttgaa tttgaaaaat attcgatgct
      481 ttcggaagat gcagttaata aatacgctaa agcagaagac atggttgaaa atattatcga
      541 ggacttcaga agcactcgtg acctaactat tcgcgcgatt cgtttagctc aagacgaggg
      601 tgacgatgct ttagaagata cattgattgc ttttaaaaat gacttagaca agaacatttg
      661 gatgctgcaa gcgttcattg gtaaagaagc attagaagat gatgacgctc ttgatgagga
      721 tgaagattaa ggtaaaagta gaagctgatt tagggattgg aattctttcc agtccttttt
      781 ccattttctt gatgtgcatc aatttttttg tagtaagaga cttatataat aaaagcagcg
      841 aatataaaca aaataaataa agggggagaa tgaattgact aaacataccc atcatgaaat
      901 tggcgaccac gcagcctgta tccgcttggt tccaatattc aatcacttag aggatagcgc
      961 gatgaattac attgctgaaa aagcccacac gaaacagtat caaaaaggag agtttctgtt
     1021 tcgttcacaa gaaaaagagg atactttata tattatcaat cgtgggaaaa tccgtattta
     1081 tcgattggca gactctggca aagagcagct agtgcggatc ttgaaccctg gtgatttcac
     1141 cggagaatgg accttgttca acccggatgc agtacacgag gaatatgccg aagcaacccg
     1201 agataccgtt gtctgtatga ttcagcaaaa agatgtccaa gattttctgg aacaataccc
     1261 agctatttct ttaaaactat tggcggaaat gtctaaacgg ttagaaagtt cagaacgtca
     1321 aacgacacaa gtagccgtgg agagtgtcat tacccgttta gttttgtttt tggcagaaaa
     1381 tgtggaacct gaaatgggca actctcccac catcaccctg ccgatggcaa aaaaggacat
     1441 tgcttcctat ttaggaacga cacctgagac catcagtcgc aaatttggag aattggagga
     1501 cgaaggattg attcaacagc tgtctgggaa aaggatcaag attcaggatt tagatgattt
     1561 attgctttac agcgaataat cggacacact tttttctaca cgttggtgtt ctgtcgctct
     1621 tcattaacaa cgggacagaa ctcagtgctt ttgcttccat ctgtccgttt ttggcttttt
     1681 taagacagaa cgaccttcat tcattggaaa aataaaagca caaacatgat aaccctcaag
     1741 tttttttgtt ttatttttct ttaagatagg gttgtcgaac aaaacgtaaa aataagtagg
     1801 gtgaatgtgc attgtttttg ggtgatagtt gccatcacgt tgtcagcagc gggggcattc
     1861 tttgtcgtcc ctttcaccaa gaacacgatt ggcggcgaag caaaaacgtc taacgttgtt
     1921 gaggcagata ggttagctat ggaaaaagaa gaggaagttg taaaaggagc cggcgtaatc
     1981 ggacacggaa aagtggcgta ttacgaagcg agtgaccagg gagataaaag tgtattcact
     2041 gtttggtttc catggagctt agccggaatc ttgttcagca tcaccatgac tagaatgacg
     2101 cgaaaaattg aagaaatgga gcaaatagaa tgggattcgt attaggcgtt ttgaatcccc
     2161 atgtggtgga gattggttct gttgtgattc attggtatgg agtcattatt gcagcgggca
     2221 tattagcggc tctccagttg agcaccaagg aagcaaagaa aaaaggactg gaagaggata
     2281 ccattatcga tatggcctta tgggcaattc cgattggact cctcggcgct cggctttatt
     2341 atgtgttatt tgaacttggt tattatctgc aaaatccagg acaaatcctt gcgatttgga
     2401 atggcggcat tgcgatttat gggggattga ttgcaggagg gggtacgcta tattggtatg
     2461 caaagaaaaa aggtacttct ttggcactcg ttcttgatat tttagcgccc aatgtattgt
     2521 tagcccagtc cattggtcgt tggggcaatt ttatgaatca ggaagctcat ggtgggccgg
     2581 ttactcgtca attcttggaa aatctttatt tacctgaatt tatcattgaa caaatgaata
     2641 tgaatggtac ctactaccat ccgacttttt tatacgagtc attgtggagt ttgttgggct
     2701 ttgtcctcat cgtcactata cggaaccgaa aacagctttt gcgtcaagga gaagtcgctt
     2761 tgagttacgt tttgtggtac tcagtgggtc ggttcttcat tgaaggtatg cgaacggaca
     2821 gtttatggat tggcgagtgg atccgcgttt cgcaagcctt gtctctggcc ctgtttattg
     2881 gcgcgattgt agtatggttt atacgcagac aagattatcc accaatttct tattattctg
     2941 atggcaataa ggggcagaaa aagactatta agatggtgaa ttgagcaaaa agataaaaag
     3001 aagtgcaaaa cttgatatgc gtcaattttc gtttgctaaa agtgagctat actacagttg
     3061 taaagaggaa aaggcagtgt tcattaatct gctgccgata aaataaaaac acataaagga
     3121 gataggaatt atggaaaaag ctatattgca attagaaacg ttgtcttgtc caagttgtat
     3181 gcaaaaaatt gaaggtgccg tgaaatcagt taacggtatt gataaagaca gcattaaagt
     3241 attattcaac tccagcaaag tcaaaaccaa ttttgattca gctgtcactt cgattgaaga
     3301 gattcaaaaa gctatcgaaa acgtaggcta tccggttctt aaagcaaaag tcaaggccgt
     3361 ttaacagatt aaatgaacta ggcaattctg gaagaaaagc tatttttcca ggattgcttt
     3421 ttttgttgca atccgattcg aggtgcttag aaacgataaa agagaacttt ctaaacttga
     3481 tgtcagtcaa ttaattactt aggcaattat cttatactgt gtttatcaat aaaagagaaa
     3541 ttaaatttgg agggaaaaag catgcaacaa tatatattaa gcaagaaaaa tgttatcacc
     3601 gtcatcagtg gattgttaat cgtactcggt ttcttcagtc actttgtttt agaaaacgta
     3661 ggactttcag agtggtcttt gatcatcgcc tctgtctttg ggattacgcc aattgccatt
     3721 caagcgtttc aagcaatgaa agtcaaagtc atcagtattg atgtcttagt cagtattgca
     3781 gcgattggtg cgctttttat tcaaaattat gaagaatcgg ctattgtcac gttcttattc
     3841 ttattcggac actacttgga acaacgaaca ttgaaccaaa cgcgatctgc tatcaaagaa
     3901 ttgactgaaa tggcacccga aagcgccttg aaacaaatgg ataatggcga atttgaagaa
     3961 gtagaagtgg atgatataga tgaaggggat atcttgctcg ttaaaacggg tgcgaaagtt
     4021 ccagtagatg gcatagtcct tacgggtgaa gggcatatca atgaagctag cattacaggt
     4081 gaagctattc cggtcaacaa gctagctgat gcagaagttt ttgcaggaac cattttagaa
     4141 aacggaacga ttcaaatcag agctgaccga gttggtgagg acaccacatt tggaaaaatt
     4201 attgaactcg tggaagaagc acaagattct aaatccgaag cggaacggtt cattgatcgc
     4261 ttttctaaat actacacacc agctgtcttg gttctggcaa ttgttgtatg ggcgttcagt
     4321 caaaatattg agttagcaat caccatcttg gttctaggtt gcccaggcgc attagttatc
     4381 ggagtgcctg tctcaaacgt tgccggtatt gggaatggtg ctcgtaacgg tgttctttta
     4441 aaagggagtg aagtcattca agacttcagt aatgtggata caattgtatt tgataagaca
     4501 ggtactttaa ctgtcggaaa cccaaccgtt gcagcgactg aactgtatga aaaagatcct
     4561 gctgaaacgc ttggctatct ggccagtgtg gaacgggaat cagatcatcc attagcaaaa
     4621 gcggtcttaa atcaaattgg agaaacaaac ttttatcctg ttgaaggaac tgaagttgtg
     4681 aaaggcggcg gaatcgtttc aagtgtagct ggacatagag tggctgttgg gaatgtggcc
     4741 ttgatggaaa aagaaaatgt cactctcagc aaaaaagtgc aaaaagatgt caaacggttt
     4801 gaacaacaag ggaactctct cgttttgaca gcggtcgacg gtgaattaaa agtactgatg
     4861 ggcattcgcg atcaagtccg tccgggtgtg aaagctaatt tgcaggaatt aaaagacttg
     4921 ggcgtgaaaa atctagtcgt tctttcagga gataaccaag gaaccgttga tgtggtcgcc
     4981 ggcgaacttg gtttgaccga agctcacggc tacatgttgc cggaagacaa atcggcttat
     5041 atcggaaaac ttcaacaacg tggtcaaatt gtagcctttg ttggagatgg cgttaacgat
     5101 agtccgtcct tagctttagc agacattgga atcgcaatgg gaagcggaac ggacgtagcg
     5161 attgaaacat ccgatgtcgt tttaatgaac tcgaacttca gcaacttgcc tcacgcatta
     5221 ggattagtaa aagccaccgc aaataatatg aaacaaaata tcgtgatttc aattggagta
     5281 gtgttggtct tgttgaccag cgtcttcttc agcgaatgga tgaatatgtc tatcggaatg
     5341 ttggttcatg aaggtagtat cttggtggta attttcaatg gcatgagatt aatgaagtat
     5401 aagttgaaag gtcgaaaaga acaaaaagaa gtatcagcac ctgcagagaa agtaaaaata
     5461 tcttaagaat aaattagaag aggctgagac aatagtccat ccttgaaatg acaaaagcgg
     5521 aaactcagat ttttaaatct gggattttcc gcttttttga gttcttgaaa aaaaataaga
     5581 gtatagagta tgttctttat aaaattaatt ttcgtgtaaa tgattaaaaa atttaataat
     5641 aaaatttaaa ttcctattaa gttgtaacac atgaaattgc ttataatagt gtattgaaat
     5701 taaggtagat tgacaaacga gtgatcaaat agatatacta ccttcaaacg accgtttgaa
     5761 tgtgaggtga gatgaatgga aaaagtttgc caagtgacta tcgtacataa agaaaaagta
     5821 aatgtaataa aaaaaaaatt ggatcaaaaa gatttttcaa acttacttgt gttagggaaa
     5881 tgtttcagcg attcttctag gattaaaatt ttctatgctt tagaaaccta taaggaaatg
     5941 tgtgtctgtg atttagcaga aatacttact gctagtgtcg ctacaacgtc acaccattta
     6001 cgttttttaa aaaaacatgg aatggcaaaa tcacgtcaag atggaaaagt agtttattat
     6061 tctttagcga atgaagacat cctttccgct attcgtgttt ttttaaagtt atcagaaaat
     6121 ctatctatga aatcttagtt tggaggaagt tattttgtta caaagtattt tttcagctat
     6181 cgctgtttat atttctacca gtattgatta tttgtttatc ttgctgatta tcttttctca
     6241 aagccacaca aaaaaaggta ttcgtcacat tttttggggt caatatcttg gaacaggtat
     6301 tttggtagcc gtaagtttgt ttgctgctta tgtgctaaat tttattccgc aagattggat
     6361 cattggtctt ctcggtctaa ttccgatttt cttaggaatc agagtcgctt ttgttggcga
     6421 agaggaggaa gaagaagagg aagtcgttga aaaactcgaa tctagaggaa ctaatcgctt
     6481 attctggaca gttgccttaa taacgattgc ttctggaggc gataatttag gtatttatat
     6541 tccatacttt acctcgttag ctttttcaga aatcattatt gctttaatcg tattcgctat
     6601 ctctgttgcg gttctctgct atatcagtta caaattagcc aagatttctt ttgtttccga
     6661 aacgttagaa aaatacgaac gaatcattgt ccctataatg tttattgcgt taggaatttt
     6721 tattatgata gagaacggga cgatacaaac gctactaggt ttttaaaaat cataatcacg
     6781 aaagataaaa agagaggcag cgactaatca aaatcgctgc cttttttgct tttcaaataa
     6841 tgaagtattt tttagcgtag aactatctta cgtgttgtgg gagtatccct tttcaagctc
     6901 ttctttgctt gtagttattt ctattgtgat atgattctct acgcttgatt tgtgtgcgac
     6961 ttctgcaatt tcttctttta tttccctagc cttgtctatg tctgaagggt ctataagaac
     7021 cgtgatgata agggcgtttt cttccccgtc cagtgaccaa atgtgaaaat gtgagaggtc
     7081 ttttacagca ggaacatttt taatggagtc cgccaagctc tttacgttta cattttcagg
     7141 cgaaccattc aataaaattt tcattgtggt gaaaaattca ggaacggttt tgtagaggat
     7201 ataaagtgca atcaaaatcg ataagatagg atccagacga tatgcctcgg taaagttcat
     7261 tagaatactc acaatcaaga ctccaatcca ccctaatacg tcttccagca tatggaggtt
     7321 caacatgctc tcgtttttgg atgtgccttt gcttaaaatc cacgcagcat atccattcaa
     7381 tgcaatagct acgagagaaa gccagaacat gccactataa tttacgggtt gtgggtcaat
     7441 caaacgtggc acactacgat agatcataaa aaacgagcca ctaattagca caacgccagt
     7501 tatcagcgcg cccagtaaag aaaagcggtt atagccaaaa gtgaaccgtt catcttgttt
     7561 tttctctgaa taaccttgaa aaaaccaagc gaatccaatt gaaatagagt cccctaaatc
     7621 atgaactgcg tcggacataa tggacacact attgaaaaga aagccaaaga aaaattcgct
     7681 tatagagaaa ataagattta tgaagaaagc aattttaata ttctttttcg gttgattctg
     7741 attcgagtga ttatggtctt tatctgattt tgacatttaa aaacctccta agtttgtatg
     7801 ctacatacta attggtttta tttttctaat tcattaacat gagttaagac ttgttcgaga
     7861 atactaaaaa catgaaggtc atctaaactg taaagcatac tttttccttc tcttcttgat
     7921 ttcactaagc gtgcgtcttt caacgttttt aattgatgag aaatagcgga ctgttccatg
     7981 tccagagaaa tagcgatatt tccaacacta cactcttttt tctgtaaaag aaagagaacc
     8041 gacaatcgtg taggatcact aatcacctta aatagtttgc ttattgacag aatagatcct
     8101 ttatcgattg gagaagttgt ttttatatcc atagtgtttt tattcctttc atatgacctt
     8161 ccgttcatat ctatattacc atatgagcga aacaatgcta atcttttgtt tataaaagag
     8221 aagtggcgtt ctctttatct tgacaaaatg tatatagcga tataaaatga gtatacaaac
     8281 atatgattaa ttagtcatat gtaaggtgga ttcattacga tttacttttg gaataaacga
     8341 aaggagtcag aaatagcaga aatttatgtg attcaagaag taaatgatgg aaaacaaagg
     8401 aattataaat tatataggga ggcaatagaa gtggaaacta tccaagaaca acagtctcaa
     8461 gaaaagcata atcataatca caaccacgat cacgaccatg atcatgggaa aatgccagtc
     8521 gttttgtact ttgttggttt agcattagca gtgattgctc tatttttgaa tgaagattat
     8581 cagttggtac aaaatgtttt gttctcaatc gctacaatca gtgccgggta tcacgttatt
     8641 cttcttgaag gccttggaga aacaattgag aattcaaaag cacaaaaaaa gttcatacct
     8701 aattctcata ttttaatggg attagcggca attggagctt ctttgatggg gaatttttgg
     8761 gaaggaacat tattgattct tattttttct ggcgcacatt ttttggaaga ttatgcagaa
     8821 ggaagaagca aacgagaaat aacgaaatta ctcgaaatga atccaacgac tgcccggtta
     8881 atcctgcctg atggtagtac aaaaaatgtg gatgtcagtg aattaaaagt gggagatcaa
     8941 cttcaagtgt tgaatggcga tcaagtacct attgatggcg tcattttgtc tggatctaca
     9001 tccattgatg agtcgtctat tactggagaa agtatcccga aagagaaatc caaaggagat
     9061 ggcgtcttcg ggagtacaat caatggaaca ggtaccttca cgatgaaagt caccaaagaa
     9121 aacaaagata cagtattttc aaaaatttta caattagtga atcagaacca agataaccaa
     9181 acaaaagctg cgagtattat ccaaaaattt gaaccgaaat atgtcacagt tgttttaatt
     9241 gccattcctc tattcatgtt attggctcct tttctacttg attggacatg gtcacaaagt
     9301 gtctatagag gattggtcct tttagttgca gcttcaccgt gtgctttagc agcagctact
     9361 gtctcggcaa cgctatcgac gacttctaat ttagccaaaa aaggagtcct ttcaaaaggt
     9421 agttcttacc tgtctcaatt agccgatatt aaagcaattg catttgataa gacgggcacc
     9481 ttgaccaaag gaaaacctga agtaaccaat tattattttg ctgattccgt gaacgaagaa
     9541 aacatgattg atatcgtagt agctcttgaa aaagaatcca atcacccctt agcagatgct
     9601 attctaagaa agtttgagca aaaaaacaaa ctaactattg aagtagaaaa ccaaattggt
     9661 aaaggattga cgggagatta caaagggaga aattatcgta taggaaaacc gacttcgttt
     9721 gatgatgttt cagatgaata tagtcgttta aataatgaat gggcgtcaga aggtaagaca
     9781 gtcgtatacg tagcagtaga tgaagaggtt ataggcctta ttgcccttat ggacgttccg
     9841 agtgaatatg ctaaagaaac cattgaatat tttaggaaac aaggtataca caccacatta
     9901 attactggtg actcagaaat gacgggaaaa gcggttgcta aacaattagg aatagatgaa
     9961 gtgattgcga atgtcatgcc ggaagacaaa tccagaatta tagacgaaca aaaagaaaaa
    10021 tacggcgtga ccgccatggt tggagacggt gtaaatgatg ctcctgctct tgttaatgca
    10081 gatgtgggaa tcgctatggg agatgggact gatgtggcag tagaggtatc tgatttagtt
    10141 ttaatgcaaa acaatttatc taaattggta caatctcata atatttcttc gaaaatgaac
    10201 cgtgttattt ggcagaatat tattttttca atggccgttg ttgctttttt aattgtcgtt
    10261 agtttcttag gcttaacgga tattgcaatc agtgtcatta ttcatgaagg aagtactttg
    10321 gttgttattt tgaatggact tcgattgcta aaggcagtct aaagaatgat tgcacaactt
    10381 caaattaatc gagtaataga gataattaag gattacacta cattttttat ctctattact
    10441 tgtttatatt tatctagatg ttcaaagtca aaatgatata tcaaccatac tcttgtggcg
    10501 cgggttgaat ataagataca tgaaattgga taaaatcatg tatcaagaat cctatcctta
    10561 tagggttctt tttttttact ccccctaaac acacgatttc gtgttgtaat aactataatc
    10621 atgtattcga acagactaaa aaggagggat tgtcatgggc tataatgttc agccactacg
    10681 gtcgcaacag gagattaatg attttttatt ttgcctgcga cggaataaaa atgcggaacg
    10741 tgacgttttc ttgtttctaa ttggaattaa cagcggtctg cgcatgtccg acatcgttaa
    10801 actcaagaaa aaagacgtga ttacctcaaa aaacccgcgc atcgtggagc aaaagacagg
    10861 gaaaacacgc attttatact taagcagctt acaggacttg attcacggct ataccgcacc
    10921 cttagatccg gaggcttact tgtttcccag tactaagggc ggccatttag aagtcaatac
    10981 ggtctaccag atgtttcaaa aggtcgcgaa gctgttagga agggacgata tcggcaccca
    11041 caccctacga aaaacctttg gttaccacta ttacaagaaa accaaagacg tggccacctt
    11101 aatggaaatc tttggtcaca gcagcgagaa gattaccaaa cgctacatcg gaattaatga
    11161 agatgaaatc agtgaaacgt tattaaattt tcggttaggt ttttgattgt attatataat
    11221 agataagcac agtaagacgg ttataatcac ccacagtatt ggacaaatca accttttttt
    11281 ggtatattat atatacaaat gagagcaggc tcatagtcaa cttgatataa atccggaaca
    11341 taagggtccg gcgggtggcg agcaccaaaa ctaaactcga tacaaatccg gaacgtaagg
    11401 gtccggcggg tggcaagcac caaaactaaa cctgtacaaa aggctgctct tttgagcagc
    11461 tttttttatt gggaaaaagg agcattcttc gcacgcggca aaaaaagaat acaaacgcat
    11521 gtctataaaa gagacaaccc aaattaccag acagttaaac gcgatttata aggctgctca
    11581 tctcttacaa gaacattttg tagataaaaa agtatccttt gtcggagaag tctcaacggt
    11641 agcgattatt ttttcgacaa ctaattttat gcacctctgt ggcattgatt atcgcagagg
    11701 cacacacttg ttttttcaag atgccttaga caggaaaata aatttacagg atattcaaat
    11761 caaaacggat gggacgacct ttcagaaatt acaagtaata ggtagccttg atttattatt
    11821 ggggaagcat atttctattg ttggcagagg tgtttactct tctcttcgct atgatgcagc
    11881 tattcgaaca aggaaaaaaa tattggctct gtctttgaaa caaaacggat taatctatat
    11941 ccctatctct ttgttaaacc tatcatcaaa ggaaattgga cctggacaaa aagttactgg
    12001 catttttagc gaggatttaa catccgggga acttaaaatg attatggaag tcatcgatta
    12061 atcattaata gtgatatgcg acgtcatttt gaagtaatta ttctattttg ggttataaaa
    12121 taaagcattt taagacgatt tcaaatcatt catgtgggtt atttatcacg gatgagcttg
    12181 aaatcgtctt ttatacgtat caaattgaaa tgttcggcat acaacctatc gttgttacta
    12241 cattactaat tgtcacttgt taaggaactt ggatcctttc taaacattcc ctagagataa
    12301 attttacttt atccctccgt taatatccaa tttaagcacc tttccgattc agggttaatt
    12361 tgcatatcaa gtgcagcttg tgttctagta agattagccc ttttagtccg gctgagttga
    12421 cttatggata taagatatgg tcatagcaaa tagatactac gtatagtctg ttaatttagt
    12481 gtcattaatc ttaa
//
LOCUS       DAFENC010000065        12432 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.067, whole genome shotgun sequence.
ACCESSION   DAFENC010000065
VERSION     DAFENC010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12432
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.067"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..190)
                     /locus_tag="LP493_002509"
     CDS             complement(<1..190)
                     /locus_tag="LP493_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134621.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGC"
     gene            complement(200..1015)
                     /locus_tag="LP493_002510"
     CDS             complement(200..1015)
                     /locus_tag="LP493_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBL2134622.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(1277..1720)
                     /locus_tag="LP493_002511"
     CDS             complement(1277..1720)
                     /locus_tag="LP493_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HBL2134623.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(1854..2192)
                     /locus_tag="LP493_002512"
     CDS             complement(1854..2192)
                     /locus_tag="LP493_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL2134624.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(2180..2557)
                     /locus_tag="LP493_002513"
     CDS             complement(2180..2557)
                     /locus_tag="LP493_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBL2134625.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKEIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            2781..3974
                     /locus_tag="LP493_002514"
     CDS             2781..3974
                     /locus_tag="LP493_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBL2134626.1"
                     /translation="MTTYQRKVLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(4140..4562)
                     /locus_tag="LP493_002515"
     CDS             complement(4140..4562)
                     /locus_tag="LP493_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2134627.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            4957..5151
                     /locus_tag="LP493_002516"
     CDS             4957..5151
                     /locus_tag="LP493_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134628.1"
                     /translation="MVAGSLLSGCGATTSTTQSTSSDQASSSSTTISESTADSSKEQE
                     QIEKKKEEKQKAEKAALEKK"
     gene            5148..5594
                     /locus_tag="LP493_002517"
     CDS             5148..5594
                     /locus_tag="LP493_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134629.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQEAIAQQQAEQARQQSA
                     AEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLS"
     gene            complement(5804..6976)
                     /locus_tag="LP493_002518"
     CDS             complement(5804..6976)
                     /locus_tag="LP493_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBL2134630.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(7182..7997)
                     /locus_tag="LP493_002519"
     CDS             complement(7182..7997)
                     /locus_tag="LP493_002519"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBL2134631.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNTI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            complement(8147..8593)
                     /locus_tag="LP493_002520"
     CDS             complement(8147..8593)
                     /locus_tag="LP493_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HBL2134632.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            complement(8590..9594)
                     /locus_tag="LP493_002521"
     CDS             complement(8590..9594)
                     /locus_tag="LP493_002521"
                     /inference="COORDINATES: protein
                     motif:HMM:NF037639.1,HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBL2134633.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKIKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            complement(9634..9963)
                     /locus_tag="LP493_002522"
     CDS             complement(9634..9963)
                     /locus_tag="LP493_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HBL2134634.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     TEIKTSD"
     gene            complement(10089..12416)
                     /locus_tag="LP493_002523"
     CDS             complement(10089..12416)
                     /locus_tag="LP493_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBL2134635.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSAIETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
BASE COUNT         3513 a         2430 c         2272 g         4217 t
ORIGIN      
        1 tgcaacctgg accaataaaa agtaaagaaa aaataaagga aaagacattc cttccatcta
       61 tcgacaaaag gaacgcagct gctatataca agatattgac acaccaaaaa caaaggctac
      121 ttgccaatga ttgatacaac caataaaaga attccatata aacatttttg tcaaaacgct
      181 gctctttcat aatcacctcc tattccttca ttcctgatga agcgatccct tctacaaaat
      241 atttttgcat cgctaaaaat ataaaagcaa caggaagaac agaaacaact gaggcagcca
      301 tgattaatgc gtactctgca tcaaatagcc caataaacat tttcaaccct aactggattg
      361 ttttattttc cgtagaagac aaataaatga atggccccat ataatcgttc catgtattaa
      421 cgaatgtgat gatcgtcaaa ctggcaatcg ccggttttgt aagaggtaaa atgatcttgc
      481 gatagattcc ccactctgat aagccatcga tccgcgcact ctcacataaa gaatctggga
      541 tactactgta gtattgcttc aacaagaaca caccaaaagc attgaacgct tgtaatagca
      601 ccaacgacca caacgtatat gttaaaccca cttttctcat cataatgaac tgcgggatca
      661 tataagactg ccaagggaca gcaatcgtgc cgatatatgc taaaaataaa atatcgcgcc
      721 ctttaaaatt tagtttagaa aacccgtaag cagcaaaact agaagtaaac aactgaatca
      781 acgtgatcac aacgcttaaa aaagctgtat tcttaaaaaa tgtcactaaa ggaatacgag
      841 accaaataac cagataattc tctaaatgcc aagttttagg gatccattga atcggaatcg
      901 tgaacacttc attatttgct ttgaatgaag cagaaaccat ccataaaaaa ggaatgatcg
      961 tcaataaagc taatacaatc agcagaatca tacccaacca ttgaataaag ggcatgtttt
     1021 ttgaacgaat ttttgctttt tttctttcat ttcgaacacc tccaaagtta taatcttcat
     1081 ttctttgtaa tgattacaat ccagaacaac ggttattata gctgattcat ttccgttctt
     1141 cttatgtttg taagcgctta tttaacaagt tatgtaaatc tctttatttt ttttgattta
     1201 aaaatgaaaa aatacaaaag caagactgtc atacgtctcg cttttgtatt gaaatttctt
     1261 cgattagaga tacttattac tgttcaaaag cttctttgaa acggtgaatc aattcattga
     1321 ctacaggtga taaaatccga ttctttttcc agactagcat gcagttcgtt tcaatcattg
     1381 ggtcaagcgg aacgaatgtc actcgctttg aaagatgact tacagcacct tctatgacta
     1441 aagcagcacc tacctgattc tcaattagcg caaatacatt gaaaatcaaa ttgtacgttc
     1501 ctgtgatcag caactgctcc ttttttatgc ctaaccagtc agcaaacatt cgctgtattt
     1561 ctggacgctt tgagatcaaa agaggtacat tcgcaaagtc ttcttttgtt atcacgtctt
     1621 tttttgctaa aacagaattt tctaaaatga gcaatcccca tttttccttt cttggtaaca
     1681 aaatcgtttc gtatttctct gtatctactg gatctagcaa aatcgctaaa tctaacaggc
     1741 ttttttctag tcactccgtg atatcatcac ttgttccgct gtggatatga aattgaacgc
     1801 tgggataatc acggatcaac ttttctagta atagtgccaa tgtattcgaa ttatcagctt
     1861 ccacacagcc gatcgtaaat cggccgctga ataattgttt ttttctgttc tcgaattctt
     1921 gagtggtttg attcgttaaa tctaaaattt cttctgctcg gcttttttag aaaataacct
     1981 gcttctgtca agatcatttt gcggttttcg cgtacaaaca gttctgttcc tagttcctct
     2041 tctaactcct tcagttgtcg gcttaaggtt ggttgtgtaa gatgtagaac ttctgcggct
     2101 tgagagattg ttccttcttc tgcaattgtc caaaaatatt ttagtaagcg taactccata
     2161 gcgatgctcc ttgatttttt tacttgatac attccatttt atttctagat aacacacgat
     2221 catatttctt gatttttcct tgtaaacgtt ccaaacactc ttgcatttca gcaatttctt
     2281 tcgtcaaaag ttcactttct tcaatcaaaa gcttacgccg ctcaaataca gttgcttctc
     2341 cttcgctaga taggcgaata tattcaatca aagactcgat cgataatccg gcatttcgca
     2401 tacagatcgt aaagtcgacc cattttaggt cttcttctgt ataatcacgg attccgcctt
     2461 ttgtccgatt aactggtgga atcaacccga ttcgttcata atagcgcaat gtatcggccg
     2521 aaatgccctt ttcttcactg acttgtttga tattcatctg atcactcttt ctcttaattt
     2581 cttgccactt tacttatgta ttttatttat tctacaactt taagtgtact ccaagtcaat
     2641 actcatttct attaaaacta agctggatta tctatatcgg ttgtttgtgt attatttcaa
     2701 ataaaaaagt cttgtttttt tattcttttt tggatatact tttaacaatt tagggaaatt
     2761 ttaggaaaag gggtataaaa atgacaacgt atcagcgaaa ggtattatta tcgacatcgg
     2821 cgggaattgc tttagagaat atggatatta tgtttttagc tttttcatta tcttcaatga
     2881 ttacttcttt tcatattagt ggtacgcaag cgggtttcat ttcaacgatc actaatttgg
     2941 ggatgctcat tggaggtatt ttttttggca tcatagctga taaatatgga cgtgtgaaag
     3001 tattttctca aacggtcctt ctgttttcga ttgcttcttt attgatgtat tttgcttcaa
     3061 acatctactt ggtttatctc tttcgcttta tcgcaggtgt aggagcggga ggagaatacg
     3121 gggcgtgtat gtccttgatt tccgaaagtt tttcaaaaaa acaaattgga cgagcttctt
     3181 cggttgctgg tattggtgcg caggtcggtg cggctttggc tgcgatttta gctgctgtga
     3241 tcattccaac gtttggttgg aagatgttgt atgtcgtagg tgtactgccg gtgttgatgg
     3301 tcttgttcat tcgtcgcggc ttgactgaac caaaggaatt caaatctgta caatctgccg
     3361 aaaagaaaac caaacttagc agactgtttg aatcaaaaca tcttgcttgg caaacatgtg
     3421 gccttagtat catggtaact gtccaaattg ccggctattt tgggttaatg aattggctgc
     3481 cttcaattat gcaaaatcga ttagggcttt cggtttctgg gtcttcattg tggatggtca
     3541 gtactatttt aggcatgtct ttggggatga tgacttttgg cataatcatg gataaattgg
     3601 ggcctaaact agccttttct ttgtttttaa tttgttcatc cttatctgtc tatctacttg
     3661 tgttagccca tagccagtgg agtttggtag cagccgctgt gatagtcggc tactttatca
     3721 atggcatgta tggtggatat ggcgcagtga ttagtagttt gtatccaaca gaaatccgcg
     3781 cgacggcgaa taatttcatt atgaaccttg gacgagctgt tggtggtttt tcttctatcg
     3841 tcatcggttt cttgatggat cattatagtt taactgccgt aatcttgttt ttgagcggta
     3901 tttacctagt cagtctgctg gtcttgacaa ctcttactgg tgttacagca ttaagggaaa
     3961 gcttgcagca ttgatagttg agtctgtaaa tgacaagaaa gaggtgtggc aaaagcttgc
     4021 atctgcggta ataagaccag ccaaatcaaa aacatgagac actgtttccg tttggctggt
     4081 cgtattactt gatgcagggc agctttttca actgctaatt tccttctatc tggcggcgac
     4141 tattctttga cgtccgtcat ttcaaagtac tttactaata acttagcata acgaaaaact
     4201 gtggatacac tcgtatattg agcgtctgca taatcttcca aatttttctc aggatgttga
     4261 tacatgaatt caatcaaatg ataattatat gattttctgt agaaatgaag ataaataatg
     4321 tagattggga agttctcctg cttttccata gaaaagcgcc gattattctc attcttcaaa
     4381 atgaccttat caggatattt ttggaacaat tcttctaaat ctgttagata attcaagata
     4441 gacttacttg ataccttcaa ttcgttttgt agttcttcta ttgaacacca acgttctgtt
     4501 tcaagcagta aatgaatcat tttaattttc ttttgagaaa cttttgttaa aaaagtctgc
     4561 atattttctc ctcctgtatc tactttacta tactacatac aagaaaaaaa acggatacaa
     4621 atatcatatt gtcacaccgt caatagtgca taaacctgtt attatttctc tttttttcct
     4681 aagtattcta ttgatatgaa tcatttaatc gtttattata taaatgtcaa taatctaata
     4741 ataaaataac gtacatattt tattattgca tacttaataa cagaactata gcaaaaaatc
     4801 ccgtgtatca acacgggatt agattaagtt tcctcaatca ctattcataa cacaattatt
     4861 ataacaagta agtaaacaat tgaaaaggac atttattgaa aacggttgtt ttttacttaa
     4921 ggaggaaatt tagcgaaaaa attagttgca ttgtttttgg tcgcaggaag tttgttgagt
     4981 gggtgtggtg ctactacgtc tactactcaa agcacaagtt cagatcaggc ttccagcagc
     5041 agtaccacga tctccgaaag tacggcagat tcatcgaaag aacaagaaca aattgaaaag
     5101 aaaaaagaag agaaacaaaa agcggaaaaa gctgcactag aaaaaaagtg acagaagcgg
     5161 aatctgcttt gtcacaagct gaagcaaatc ctacaaaaga aaactatgca actgcttcag
     5221 cagctatcca agcgctacct gaaaacaaac aagagttgac aagccgtctt gctgcaattg
     5281 attccacaat caaagcaaaa gaagcagaag aagaacggaa aaagcaagaa gaaattgcac
     5341 gacaacaagc agaacaagcg caacaagaag caatcgcaca gcaacaagca gaacaggcga
     5401 ggcaagaagc aatcgcacag caacaagcag aacaggcgcg acagcaatca gcagctgaac
     5461 aggcctctca gcaggcacaa gccgcagctc ctgagcaaaa taatgaacaa actgtctatg
     5521 tcacaccgac cggttcaaaa taccatacac ataaatgtgg aaatggtacg tatacccctg
     5581 ccactttaag ctaagctcaa gctcgtggtt taaccccttg ctccaaatgt tatggaaact
     5641 aattcaaaag ttatactata ataataaaat tcttctgaaa cataaaaaaa tagaagatgg
     5701 cgttccagat agtaaaccaa aaataacagt ttacacgtcc atttcgtcag cttctctctt
     5761 ttttcattta gtctgttccc tctgcttttt tggacatctt cattcattct ttctcaatca
     5821 aatagtacac ctctttttct tttcgcagtt tatatcttcc ttttttcaat ttcattgaaa
     5881 actgtttcga atgtttatgt tttacatgga ttttaagcag gagctcctca tgttgcaagc
     5941 gatagttcct gccttttaaa tcagaaaatc tcactagtcc gtattcatca gaagctttca
     6001 caaatggaac tttttctcta gtaatatagt gtttgccgtt gagcgttttt acagaaaaga
     6061 ccattccttc gattggtcgt ccgtttgtgt tctttacata aaaagataaa ggatagtttc
     6121 gcttagcgat ggccaaagaa tctaaataag cgatgagtag ccaaactaag ccgattgatc
     6181 caagtagtat accgataaac caaataaaaa atttccattt tttccattga tcaattcctt
     6241 ggatcgcttt ttttgcctct tttgcttgat aaggaatacg atgccccgtc acaagcagtc
     6301 gatgtgtatt gaccatataa ggagtacagg taagcaaagt cacgagatct ctgccttttt
     6361 ggatacccaa agaatctact tcatcaggta agaccacttg gattttttct acttgatacg
     6421 ccaatgtctt tccattgatc tggatgaaaa actggtctcc ttttttcaac ttaggcaaat
     6481 ctgtaaataa ttttgcttct gggagtccac gatgcccaga aagaacggca tgggtgtttt
     6541 tcccgccagt cggataagaa ctttcttcca ataatgacgt tcctttttgc aaaaatattt
     6601 ccgttgtctg atcgaatata ggtaagctga cattgatttt tgggatttcg atgactccaa
     6661 gcatatgttc cataaaaaag gcattactag gtaaatcttt taatgctttt gcatcaactg
     6721 cttggttgaa actgcctatc cctggtgata cgttttgctc tgccaactgt tggtttttct
     6781 ttgtcatttt ttcctgctgt ttttttattt cctctgaatt cttattcgat gcttgctttt
     6841 gataatggat gatcatttgc tgggcaagaa aatcattcag tgaatcttct acaaaaggat
     6901 aagaaaagat cccgatccca acgactaaaa tgattgccat gaagatgtcc agtattctta
     6961 ttctgctttt attcatcatg tccacctatt ttctaatatg tatatgaaga ggttgtgaaa
     7021 tcagcgcctt gacctgagta ttagcgaagc aaacggcaaa atagttcctc ctattttgcc
     7081 gtttgttgag cgaataccaa gagaccgacc acttgtcaca acctttctcc ccatttgaat
     7141 cactatcgtt tatttatcgt atgatttttg tttccaatag tttaagcttc tgtttcttga
     7201 tggcgttttt tgaaatagat cactgctcct ccaactaaag cagtacctac caagatgaat
     7261 acgatgatcc ccataccacc agttgaaggc aagattcctt taggttggtt atcgatcgtt
     7321 gtttcatcag aagttgttgg atcatcatct actgtaaatt cagtgtacgc agcttcattc
     7381 ttaggtaatg cgtagccttc tggtgctttt gtttcttgaa ggcagtatgc cccttgtttc
     7441 agcccttcga ttgaaaattt cccttctgaa tcagaaatca atttcacttc ttcccagtca
     7501 gaacctgtga cttcatctga ccaagcatat gggtattctc ctgaggcaag gtttgctatt
     7561 tttttcatta atttaacagt tggatctttt gctcttagaa tagaaaattc tgcatcggct
     7621 aatttttctt gcgtgttcac atcttgtttg atgaagtgga aatcaccgta gttttggaca
     7681 ttttctacag taatcgtgtt atccgtagtt gtattttccc gattgactac accgtttgga
     7741 ttcccaagat tggcttcatc tgcgccatgg atgataccgg ttgtttgttg caattttccg
     7801 ttttttacta taaaagtagt ttctttttgt ggattggtta attgataacc atctggtgct
     7861 tttgtttcaa ctaaagtata attgccgtct attaatccat tgacactgat ggatccttca
     7921 gtatcagttg tgaatgtcaa cgctgactca gcaggatcat agagagcgac accagtgttt
     7981 tcatcaaaac cggtcacgaa ttgattctct gaatttttga tctggaattg cgcccctgct
     8041 aacttatcta cccctgaaaa gttcccagct ttctggattt tgatattgct ttctttgatg
     8101 acatttttag catataggtg aatcgtgtct aaaggtttgt cagggtctag ggtaagctta
     8161 acacgatatt tggcgacgtt tcgacaccgg gctttggtgt ttctacaaag acgtatacag
     8221 catctttccc atcagattta cctggaagag tcaggttagc taatccttca ccagaagtcg
     8281 ttacacttgc gaagggtgta gcgtctgctg gaactgctgt gtctttactt ggatagtacg
     8341 tagcagtgat gtcatatacg ttgaattcaa cgccgttcaa cggttcgcta ttcggaaatg
     8401 tcaattccgt tccgttgttt atttgatttt ctggtgctga agtgaatttc aatttatgca
     8461 aattaaccgt aacattttct ggtgtaggtg atacggctgc agaaacctct gcagttccta
     8521 ggccgagaac gaaaggaagc agcatgatag cagttcctaa aaacgtccat atttttgttt
     8581 tgatgttttt cattttattt ccctcctatt gtttcctttt tgttgttttt tataaaacca
     8641 agctgtccct gttgaaagga ctagcaataa ccctaaaatt gagaaacctc caagcatctc
     8701 ttcgcttgtt tttggaaagc ttcctccatt tttttcattt gatggaccat ttgtctgcat
     8761 ctgaactggc gtttttccat tattcgtcgg atttgctttt ggttcgttga tgatttccaa
     8821 tggtatagga tgaagcggat cataactgcc tttttcaact tcaaagagaa tggttgattg
     8881 actcaatata tatcctttag gcggtttaat ctccactagt tcgtaacttc caaaagacaa
     8941 tccatggaca gaaaatgttc catctttact ggaagtaaaa atcgttgctc ttgaatcatc
     9001 tttggctacc caatgattta tcccgttttc ttgcgctaag tattggtcat tttttttgac
     9061 tagaaattga gcatctgcta gtttttgttt cgtttgccga tccactttga caaattgttt
     9121 gcctcctgtt tggatggcaa gatgtgtttc tactgtttga ttgtcagtcg tcaaacgtac
     9181 atcgttatca aatgtcgttt tttcactgtt ttctttcaat gtcatttggt aacggatcgt
     9241 taattttttt ccagcaaacg aactaagatc ttttccagaa tctgataaga caaaaccatg
     9301 ttttattttt tgtgtgtgaa atgtatgaat cttgtctcca ccaatcaaaa aatcgatcgt
     9361 ttctggttct agccataact gaggatcagc tgtatctttg atcgtatagg ttcctatctc
     9421 gttgatgttc tcaggaattg ttacggtgat gagataaggg actttatccc catctgcaaa
     9481 atctgtctgc ttattctcta ctgtttttgt taatgtgagt gcagcaggta ttttttgttc
     9541 gctctttgga tacaagtgga tggtcgtcaa tttatgatta gatgaatctg tcacaggaag
     9601 cacaacgaca aatggtgctg atttttcttt tacttaatct gaagtcttta tttccgtaaa
     9661 tcggtaaaca gcgtcacgac cttgctcatc tttgtccgat gcactaaaag aagcaatgcc
     9721 ctcttcctcg tctactgttt ttgtcacatt ttctgccagt attttttcac tatcactttt
     9781 ttgtgctagt tttctttgtg cgtcttccac actacttcct tctgaccgca gcttgtaaaa
     9841 ttcatccgag acatcatata tagcgaaagt aacgccgttc aaccctttta ctccttgaaa
     9901 gttatccggg atatttattc cgtcgttttg actgatactt ggcatcttat cgctttcgaa
     9961 cattcgatta tgcaaagtaa atgtaatagg tgattctcta gctgacacag tcggagaacc
    10021 tataaaaaag accagtagga taaaaaagag aacagcaaat atatccacac gtacattttt
    10081 tgtttttttc atcgctgttc acctgctttt ttcttacgat ggataaaata aaagaagcca
    10141 gaaaaaataa agatcagtcc taaaaagaca aagggcagta gacctatccc acctgtcgaa
    10201 ggaagcaaga gagtcggatt gatcgtcaac ttagcggtat ctgttgcgat aatcgtataa
    10261 ttattgttta cacttccttc gcctaaacta atcgttacta tttgtgatcc aatatctgtc
    10321 cggctgttaa ctgttagggt ataatccaat gattcgccta agacaacacc ggtaacgtgg
    10381 agatttccaa ccgaaatcga gtgactttgg gcatcataat taaaggcagc gtcatcgaca
    10441 gtaatcactg cgttagcttt atagatggta taagttcctg atgtgttggc tatatcagta
    10501 aatgacaact tgggatttgc tgctttgact ttgtctattc cgctattcgt tagtttaatt
    10561 gtatagctgc cagcattaac catatttttt gctgattgtg catctgctgt gtaatccata
    10621 ctgctaagtg ccacttgtac tggagtaagc gaactagtga caccctctgc tagcttgaca
    10681 tggattgacg ggacacctgc ttttccatca tatgtcttac tgccactgag ctctaccgca
    10741 ccgctgattt gcttaatcgt atagacatca gatgtctgca cgatagtaaa taaatagttt
    10801 gttctggcag ctagtttagc tagtccgctt tttgtcaatt gccaagacgt ataggttcca
    10861 atttcagtag gcgcagttac ttcaactccc ttttcattca tcgctttgaa atcagttgga
    10921 ttccatgtga tttgatcaat actgagatca ttgtttaaaa gggatgttga ttctgtttta
    10981 tcattaaagg catatttaac gatcggtaca acagaaagac catcatagta cttactgcca
    11041 tttgcattga ttgatactgt tgcatttgtc ttataatata ggatgacttc agaaatctgt
    11101 tttccatttg cgtcctttac gattacattt ccatttgtat ctaaactagc taaaacactc
    11161 attgctgatt ggttctttgt ttctatcgct gaaacagctg taaaggtata tccgttgata
    11221 gtaggcgtat tagtcgtcag gtcttgtgca gcacttccgt aagtaagatt cattatttta
    11281 gaaggagcaa tcatctgtcc aaaatagtct tgatacttaa tagtgattgg tgtttgtttg
    11341 cctgtatagg tcaccgtatc gacgttactt tctagggctg tgaaagaacc gtttgtttgt
    11401 gcaaaagaat agcccgttac tgctgttgga gtgataacca ctttgtcacc cacatggatt
    11461 ccagataatg tagtcccgta cgttccgatt tttgctgctc caccattgac tgtataagaa
    11521 aaagttcctg tccgattcgc attgacctga accgttgctg cttgataggt tggaaaattt
    11581 gaaacatttc ccttaccatc aacgatctgc ccatttttga tcgagtaccc cgtgaatgga
    11641 atatcatttg ctaactgtat accgattgaa aaagtactca tacctcctcc ggcaggaagc
    11701 cctccccatg ttgagggtgt aaaagaataa cttttatccg cattgggtgt aactgaatcg
    11761 atcgtatttc cagcggtagc cacccccata tagatacttt ttgggaatgt gatagtagta
    11821 ccatttactg tggagccaat aaacagatta tggatatctg gacggttatc aataaaagcg
    11881 attgctttgg ttacgccttg taacgcagtt ttatccgcac tcatcgatcc gttaaccgca
    11941 acaatgactc catctttggc atatatcact gtatatccat ctggtatggt atgtccgttg
    12001 aaattcgcag tggccgcaac agtactaaat gtctggcttc tacctgtttc tgaataagct
    12061 ttctcccctg ctgcttttgc tgctgtgatt tctttttctg tcggatcaat cagttgagtc
    12121 gaggatgtgg ttgaggttgt ctcgttgttg ctagactgat tggtgctttc tatggactgt
    12181 atttcagaat agggtggact atttgtctcc tctgtcgttt ggttagcaaa atttgacgtt
    12241 tctgtataaa cgtttacata aatacttgat aagctcccta agaaagtaaa aatcaagatg
    12301 atcgaaatca taatgggatg taagtatttt cttttagata cagctttgag tctagaaaca
    12361 aaatgttttt gacatatacg ttggatttta ttttgagttt tcttaatcat tttcatccct
    12421 cctctcaata aa
//
LOCUS       DAFENC010000066        12226 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.068, whole genome shotgun sequence.
ACCESSION   DAFENC010000066
VERSION     DAFENC010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12226
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.068"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..566
                     /locus_tag="LP493_002524"
     CDS             <1..566
                     /locus_tag="LP493_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBL2134636.1"
                     /translation="YFKSEKDTSSLTLTLEEGVEPDKVTSKVINQLKEKGSLKHLGEY
                     EVLDTAMLTKGIGQILSTITYFITAVAGISLFIAGVGVMNMMYISVSERTKEIGIRRA
                     LGATRKSIMLQFLLEGLILTLSGGLIGYLLGMALAYSVGSLIKVNVSLDLFTILLAVG
                     VSSVIGLVFSVMPASEAAKKDLIDILR"
     gene            967..1572
                     /locus_tag="LP493_002525"
     CDS             967..1572
                     /locus_tag="LP493_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HBL2134637.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            1588..2160
                     /locus_tag="LP493_002526"
     CDS             1588..2160
                     /locus_tag="LP493_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2134638.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(2412..2669)
                     /locus_tag="LP493_002527"
     CDS             complement(2412..2669)
                     /locus_tag="LP493_002527"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134639.1"
                     /translation="MANLYIENKGDLNAIITLIVVMVKSIGNITIGMLFIILAAVLIF
                     MIVIWFLNERSKDNQHRRDMEIKSIESIDYLSIITLKKPRS"
     gene            complement(2795..3610)
                     /locus_tag="LP493_002528"
     CDS             complement(2795..3610)
                     /locus_tag="LP493_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134640.1"
                     /translation="MVKIAGLSKGGKTVSQLYKQNYRDWRQFRKNIKDSYFILPTELE
                     KYLPNNKAINLYLYYCFKAKNEGGDSWHSVNTIAESLGVTTKTINTWNKTLVDLGMIA
                     RIDDNHLSKSTILLPLSSYYKLALDSSLKDVTESTVHEIDGNLVAVYHLFEWRKNEAD
                     ENYNVPYNTLCCVFKRKTQKDTIYKFILVQDEKISNFELSTPSSKIYDDAYRFECQDL
                     EALLSANNLNNIEHENFVVNTRFNLVSEKDSDLLDLLIELTKNLDKKENITVL"
     gene            4127..5452
                     /locus_tag="LP493_002529"
     CDS             4127..5452
                     /locus_tag="LP493_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBL2134641.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSMNLFTTEGTRSQRRKKLAQMIQENIKEELGLLA
                     TVGVGDNPLLAKLALDNEAKHNDGFLAEWTYQNVPDKVWNIPEMTDLWGIGSRMKKRL
                     NQIGIMSIKDLANWNPYTIKSHLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLYIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            5445..5795
                     /locus_tag="LP493_002530"
     CDS             5445..5795
                     /locus_tag="LP493_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134642.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEKIDADNEQRANQNLAKEQMTTE
                     EVAEVLNAAVIKNRSVCIQKEERNAEGYYPEDIVSKILGSDELGIYVGKNKVHYDEIR
                     HIEFYQDNKWGRLE"
     gene            5792..5962
                     /locus_tag="LP493_002531"
     CDS             5792..5962
                     /locus_tag="LP493_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134643.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHKYEYYIGY"
     gene            complement(6866..7141)
                     /locus_tag="LP493_002532"
     CDS             complement(6866..7141)
                     /locus_tag="LP493_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgO"
                     /protein_id="HBL2134644.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(7113..8066)
                     /locus_tag="LP493_002533"
     CDS             complement(7113..8066)
                     /locus_tag="LP493_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBL2134645.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            8678..10171
                     /locus_tag="LP493_002534"
     CDS             8678..10171
                     /locus_tag="LP493_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HBL2134646.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            10306..10602
                     /locus_tag="LP493_002535"
     CDS             10306..10602
                     /locus_tag="LP493_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HBL2134647.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
     gene            10703..11554
                     /locus_tag="LP493_002536"
     CDS             10703..11554
                     /locus_tag="LP493_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134648.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            11575..11858
                     /locus_tag="LP493_002537"
                     /pseudo
     CDS             11575..11858
                     /locus_tag="LP493_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345737.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         4205 a         1873 c         2286 g         3862 t
ORIGIN      
        1 attattttaa gtctgaaaag gatacatcgt ctctaacgtt aactttagag gaaggagttg
       61 aacctgacaa ggtgacctct aaagtgataa accaattgaa agaaaaaggt agtttgaaac
      121 atttggggga atatgaagtg ttagatacgg ctatgttaac gaaaggaatt ggtcaaatcc
      181 tcagtacgat cacttatttt ataacagctg tagcaggtat atctttattt atcgcagggg
      241 taggtgtaat gaacatgatg tatatatctg tatctgaacg aacaaaagag atcggtataa
      301 gaagagccct aggagctact cgaaaatcga ttatgctgca gttcctttta gaaggtttga
      361 ttttaactct ttcaggaggg ttaattggct atttattagg aatggctctt gcttatagtg
      421 ttggttcttt gataaaggta aacgtgtcac ttgatctatt tactatttta ctagcggttg
      481 gggtatcttc ggttattgga ctggtctttt ctgtaatgcc cgcttcagag gctgcaaaaa
      541 aagatttaat tgatattctt agataaaatc agaatgacaa gaatatttac gttctagatt
      601 ctaaaataaa acacaaagag accaaccagg caccctattg tttctttgta gtatagagat
      661 attctttggc ttgtaagaga tcaatagagt taggtgaccg gagttcgaaa taaaggaaat
      721 ttttgattgt ataggagaat tctttatccc taatatttag aattttgagt atgccatgtt
      781 gatgttttag attctctata aatatagagg tgtatcaaag gtcaactaga ctgtgcaaaa
      841 tagagacact tgaaaaatct atcgggggtc agaaacttaa tagtttttga cacataaaca
      901 aaatcgcgat ataatggggt tgagagtgtt tcataaactt atgtcataaa gttaaggaga
      961 tttcgcatga ttttagagaa taaattggga ttaaccaatc aagttgagtt ggctaaggtt
     1021 gaagaaaaac tcagtaaaca aaaagcgaaa gaattgtacg attgtggaaa aataaatgaa
     1081 atcgaagttg gtacatttaa aggtttatct gaaattcatg aatttctatt ttcggatatt
     1141 tacgattttg ccggaaaaat ccgatcggtc aatattgcaa aaggaaattt tcgatttgca
     1201 ccagttatgt atttagaaca ttcgttacag catattgatc agatgccaca aacttctttt
     1261 gaagagatta tcaagaaata tgtggagatg aatatcgctc acccatttcg agaaggaaat
     1321 ggccgaagta ctagaatttg gctggatctc attttaaagg aagaattgca aaaagttgta
     1381 gattggaact taatcgataa agcagactat ctttctgcaa tggagcgaag tcccataaac
     1441 gatttggaaa tacgctatct aatttccaat gctctgactg ataaaattga cgatcgcgag
     1501 ttatatatga aaggaatcga tgtcagctat ttctatgaag ggtattctga gtatacgata
     1561 gatgatttgt aaaagtaggt ggaccaaatg acgaaatatg gatatgcacg tgtctcaacc
     1621 gcttctcaaa gtacaaaaga acaaattcaa cagttgcttg agaacggcgt agagaagaag
     1681 aatatttttt cagaaaaatt tacgggtaca aaacgggatc ggccaaaatt caatcagctg
     1741 ttggctggtc tgaagcctgg agatgaaata gttgttacga agcttgatcg atttgctcgt
     1801 aacacgagag aagcattaga gatcattgaa cctttactcg atgataacgt aacgatcaag
     1861 gttttgaatc taggaacgat tgaaaatacg tccatggggc gaatggtgac acggacgttg
     1921 ttgagtgtag cagaaatgga acgtgatatg attgtggaac gtacccaaga aggaaaaatg
     1981 tttgcaagaa agaataatcc taatttcaga gaaggacgtc cgaaagcaac aatcacaccg
     2041 aagaagaggc acgcatatga actgcttact tcaggtaaat cgtataagga agttgaagct
     2101 ataaccggtt tcagtcgcag tacgcttttt agaataaaga agaaaattga agaaagttaa
     2161 aaaagaagtc tcagcgaacc agacaggtaa atacttaatg cgttctagat atgagtctat
     2221 tagcatgttg tgaaatataa tattttttta tttacttgat ttctgctcaa aaaatgtgta
     2281 tggtaactgt aaaaggtaaa gtaattaaag gtatgctagc cacgcttact atattaggat
     2341 accatcatat atttataatg aacgatttgt tcgtctacca aacaacacat atcgttcagc
     2401 gtaagtcacg tttaggaacg tggctttttt agtgttatta tcgataaata atctattgac
     2461 tctattgatt ttatctccat atccctacgg tgttgattgt ctttagatct ttcatttaag
     2521 aaccaaataa ctatcataaa aatcagcact gctgctaata taataaacag cattcctatt
     2581 gtgatattac ctattgattt taccataact acgattaaag taataatggc attcaagtct
     2641 cctttgttct ctatatataa attagccata aatcatcttc ctttcaaatt aagatacttg
     2701 tttgatacca ataaatagta agcgtggcta gcataccttt ttctgtaata gcaagtgttc
     2761 taatagtcca aacttaatga tggaccgatg ctagttatag tacagtaatg ttttctttct
     2821 tatctagatt tttagtaagc tctatcagca aatctaacaa atctgagtcc ttttcagaaa
     2881 ctaaattaaa tctagtgttt acaacaaagt tttcatgttc tatattgttt agattatttg
     2941 cggaaaggag ggcttctaga tcttgacatt caaatctata tgcatcgtca taaatcttac
     3001 tagaaggagt gcttaattcg aaattactta ttttctcatc ttggaccaag ataaatttat
     3061 agatagtatc tttttgtgtt tttcttttaa aaacacaaca gagtgtgtta taaggaacgt
     3121 tataattttc atcagcctca ttttttctcc attcaaacaa atgataaact gcaaccaagt
     3181 tgccatcaat ttcatggaca gtgctctcgg taacatcctt taaagaacta tcaagggcta
     3241 atttatagta actagagaga ggaagtaaaa ttgtcgattt actgagatgg ttatcgtcta
     3301 tacgtgcaat catacctaaa tcaactaagg ttttattcca ggtgtttata gttttagttg
     3361 tcactcctag agactctgct atggtattga ccgaatgcca ggaatccccg ccttcattct
     3421 ttgccttaaa acagtaatac agatataaat taatagcttt gttattcggt aaatattttt
     3481 caagttctgt tggtagaata aagtaagaat ccttaatgtt ttttctgaac tgtctccagt
     3541 ctctgtagtt ttgtttataa agttgtgaaa cggtttttcc acctttagaa agtcctgcta
     3601 tcttaaccaa tcttattgct cctttcttga atctgtcatg atcatacagt attttttact
     3661 tgtagtccag caccttaata tattatccta tgtaattaat ttcgtactag atagtaatta
     3721 ttttttattt aattctctag tcacttacaa ataagttata taaactacga ttaataaatt
     3781 attacaaaaa ctattaagaa aacttctaca tacaactatt acaaaactat taagaaactg
     3841 aatactccta ttttttgttt ttaaggaaag ttttttcttt tttgaatttc ttattttttt
     3901 ctaatataac taagcaaaac tggataatac gacacttatt ttcaaatttt cacaagacta
     3961 atagtaaata tccatttaat aaagtgatac aatgtgttga ttttacaaat caacagaaga
     4021 agtagggaaa taacttacct atgcttcttt ttttgtacat ttaatcgatt cttctttaca
     4081 aaaacgaacg tatgtttgta taatgtggaa gaatggagtg ttatttatga tggattattc
     4141 aaaagagcca gtaaatgatt actttttgat cgatatgaaa agcttttacg caagtgtcga
     4201 atgtatagaa aggaatttag atccattaac gactgaatta gtcgtcatga gtcgagcgga
     4261 taatacagga tcagggttga ttttagcttc ttcaccagct gcaaagaaga agtacggtat
     4321 ttctaatgtc agtcgaccac gagatctacc gcaacctttt cctaaaacgt tacatgtcgt
     4381 tccaccacgc atgaatctct atattaagcg aaatatgcag gtaaacaata ttttcagaag
     4441 gtatgtagca gacgaagatt tattgattta ctcgatcgat gaatcgatct taaaagtgac
     4501 cagatcaatg aatcttttta cgactgaagg aacaagaagt caacggagaa agaagctggc
     4561 tcaaatgatc caggagaata ttaaagaaga gctaggattg cttgctacag taggtgtcgg
     4621 agataatccc ttattagcta aacttgcttt agacaatgaa gcaaaacata atgatggatt
     4681 ccttgctgaa tggacgtatc aaaatgttcc tgataaagta tggaatattc ctgaaatgac
     4741 agacctttgg ggtattggat ctcgaatgaa aaaaagactc aaccaaattg gtatcatgag
     4801 tattaaagac ttagctaatt ggaatccata cactattaag agccatttag gtgtgattgg
     4861 cttacagctg tattttcatg cgaacgggat cgatcgaaca gatatagcga tcccaccaga
     4921 accgacaaag gaaaaatcat atggtaattc acaagtgtta ccacgagatt ataccaggag
     4981 aaatgaaatc gaactggtgg taaaagaaat ggcggaacaa gtagctattc gtatcaggca
     5041 acataactgt aaaacaggtt gtgtccattt atacattggc acgtcgatct tagaaacgag
     5101 accaggtttt tcacaccaga tgaagatccc tataacagat aatacaaagg aattgcagaa
     5161 ttactgtctt ttcttgtttg ataagtatta tgaaggacaa gaagtaaggc acgttggaat
     5221 aacctatagc aagcttgtgt acactgattc gcttcagctg gatttattta gtgatccaca
     5281 aaagcaaatt gacgaagaaa atttagataa aattattgac aagattcggc aaaaatatgg
     5341 ttttacgtcg attgtacatg cttcttctat gttagaaggc gctcgtagta ttactagaag
     5401 tacattggtt ggtggccatg caggcggcgc aggagggctt aaaaatgatt gattataatg
     5461 atcgtggacg tttaaagtgg gcaggttttt atttatctga tcatactgaa aaaattgatg
     5521 ccgacaatga acaacgagcc aatcaaaatt tggcaaaaga acaaatgacg actgaagagg
     5581 ttgcggaagt attgaacgct gcagtcataa aaaatagatc agtatgtatt caaaaagaag
     5641 aacgaaacgc tgaaggatac tatccagaag atattgttag caagatctta ggtagtgatg
     5701 agctggggat ctacgttgga aaaaacaaag ttcactacga cgaaatacgt catatcgaat
     5761 tttaccagga taataaatgg ggtcgattag aatgaacatt atccagcaat atgagctaaa
     5821 gtatataacc tttgatcagc tatcagaaga gatttggggt tatggccagc gtttgataaa
     5881 tgaggttggt gttgaacgct tctctttcta tgtagaagct gcagcaggat accataaata
     5941 cgaatactat attggctatt aaagtgcaat aaaattatat ttcttttatg ttttacattt
     6001 tgtatcaatt ctgataaaat tacctatagg taattaaaaa atataaaaaa actagttaca
     6061 accttaggac gttgtaacta gcttgaagca tactagagct aactaaaata gcactagaaa
     6121 gcaatgttaa acccgtccaa caaacttgat ttaacattga gaccagctta ttcagctaaa
     6181 tatagttgaa taagcttctt ttgttttaaa aaaacaaaag gtgtactacg aataacgcaa
     6241 gtaaaagaaa tactattaca accagtaggc tacaagtaag tattactaaa cattgcgtag
     6301 ttagaacctt tgctctattg tctaaagcca caaaattaga gatcagcttt atgatgctaa
     6361 gagcgagctg catccatgcg gacataggtt cttttgacac tattaattct cctttttagg
     6421 ataagggaaa ttgctagtag ttttttcatt agcaccatcc cccttcattt gattgagtct
     6481 agtgctgctg tgatagtttg ctgtttaata tgcttacatt cttattataa cataaatgaa
     6541 acaaacacat ggttagaggt cgtatcaatc aaaatagtgt ctcacaaacg atttattact
     6601 tactcctgct gactaacgga ctgttcttca gtaactgtaa ctatatgttt gttaaaacca
     6661 ccattacctg tagataaaaa ccaatatatt tactatactc actatattaa atatatttag
     6721 tatagtaaaa actagaaaca ataaaatttg tgaatgttgt atacccccaa acaatacaca
     6781 tattttgaag gattaggatt aataaagcta aaaatatagt aagtatacta aatatattta
     6841 ctatatctag tatacttact atattttaat cttttgatcg tctattatat ataatccgtt
     6901 cctcgtcgtt taaagtatca acataggcgt ccattgcaag tttgactatt tcatacatag
     6961 gaatatcttt tgcataacta agatcccgaa tggtttttag tacgggagga tctacttgaa
     7021 ctggttttct ttctttcgca gtgtactttc gttcccctaa ctcgacatta atatcatctt
     7081 taattgaaat atcttcagca ccaattttct tcttatcttt gttcgttggt aataatgcca
     7141 tttagtttaa tctcctttcc aagaggtagg atatgattgg ccattgagtc agcatattta
     7201 ggtgtataat caaatccttc aatatcacca tgttgttcat agtattcaat tctttcttct
     7261 aattctgtaa agatgtctgc aaaaatagcc caccatcttc gatctacata atcatttaat
     7321 tggataccat tctcaccata catttctaac cgatccgagc ctttaacaat gcttttaaaa
     7381 atgtttgatt caccatactt atcaattgtt ttttgatagt ttgcgtgttg agaggaacgt
     7441 cgcactgaga aaagaacagg caaaattcca atgatttgaa gatgagactc ttcaaaattc
     7501 gtgacaatcg gaactaaaac tttattaata aaatcttctg ttccttccat tgcgtaccgt
     7561 tttaattctt gcattgcaat aatataatct gcagcagtta agaatgcacg aaccacatta
     7621 tctgttgatg gtgggcagtc gataaagata taatcgaaat tttttctcaa ttcttctaaa
     7681 ggtttaatga aggccaatga tctcttacga cgatcaggat atttttcgga caagtattca
     7741 ttaagttctt cagatccagg agagccagcc ataatatata aatgtggact tacttgagta
     7801 atacctgaaa cccagtcccc ttttttgatt gctgcagaca tggatcgatc aaagctagta
     7861 atttgatacg ttgatccaat gttggaagta gtatttcttt gttggtcata atcaattagc
     7921 aacacgtctt tttcaaaaag ttgactagaa acaatcgcta ataaatcatt gtctgtagtc
     7981 ttaccaatgc cgccttttct acctgtaagc attacaactt ttcctagttt atctgatgtt
     8041 ttaaatgcag tccgtaagtt ttccatagtt ccctccaatt tcctatacta aatatattta
     8101 gtatacttca tatacttaat atattcgata tatctaatat actccaaatt gataagaatt
     8161 cagactttat aaggaatata gtggatatac taaatatatt tgctatattc agtatatcag
     8221 atatattcaa aatgtcaaaa tatatttgtg cgttttgcgt tgacaattta gagtgaaaag
     8281 aggtaaactt aattctatag aaaccacaga taattcacta tttacaaagt agcaaaagca
     8341 gtggtactct ttaaacagaa aaattacata aaaaaaagag acggaaataa ttgattttag
     8401 cagaatcaat tatttctgaa tcacatggtt aggacatgtg ttcacgctcg tctcaagaat
     8461 atgtaagtag ctaccaacta cttatattaa aagttgatcg gatacctttt ccgattgcct
     8521 ttattctacc aaaaaaaggc gagcaactca acagaagaac gtttatttag tgtacttaaa
     8581 ttaaatattc ttaaacactg aagagagaac acatactatg gctgagatta aagctaaact
     8641 gtgttctctt tttgtttgag aaaggacgtt acaatcgatg ttgagcgaaa tttattcagc
     8701 tattcttaaa aacggcttac gtacatacaa atatcgaaac agcaccatga aacctgcagg
     8761 tcatattgat tccagtagga gtggtgctat ctttgcgtac cgtagcaagc aattaatgaa
     8821 tgttgggcgt ggtatggtca ttacttcgga agaagctatt ttagagaacg aaaagaaact
     8881 aacgcattgg acacctaata cctatcgctt tggtacttat gcggatgatt atcgaacagt
     8941 ggttaaaggt cattctgaga aaaacttaag tcaaatcaac acatttgtag ttgatatcga
     9001 ttcaaaagag aaccatcaag gcgaaattat tttagcctgt ttagatcaag tgggctacat
     9061 gccaacgcta attttagaat cagatcatgg ttatcaagtt tattttgtac taaagacacc
     9121 aggctatgtc acaaagaaaa gcaatttcaa ggtgatcgat gtagcaaaaa aaatttcaaa
     9181 aacaattcgt ctacagttgg ctgaaaaatt gtccggagtg gatctaggat gtaaccactt
     9241 cggaattgct cgattcccac aagaaaataa tattgttttt aaagaaatga actatcagta
     9301 ttcttttgct gactggattc aatggtcgat gaagcttgaa tcagatcaaa aaacaaaaga
     9361 agatcgagaa cgaaaactaa ttgtctttcc tgagaaaaaa gaaattcgtc aagtagatga
     9421 accgtggttc gatatgttac ttcataaagc aaacatcgtc ggcggagaag gacgtcttgg
     9481 tcgaaataat gtgattttca cgctttcttt agcttattac tcttcaggtt atgcattgga
     9541 tacttgcgaa tacaatatgt tcacattcaa cgaacggtta caggaaccgc tatctgaagc
     9601 agaattagta aagattgtac gtagtgctta ttctggtaat tatcaagcag caagcagaga
     9661 attcattatt gaattgtgcc agcaatgggt ttcaccaacc ttaaaaaata atgatctgtt
     9721 cattcaacga cgtggctggt ggaaatttaa aaagccacga gatcaaagaa aatatagtca
     9781 taaaaatgaa tggaaagaag atctattggc ttatctaagc gaaaaaagtc ttgctagtga
     9841 gccttatttg aacctgtcaa aaaaagaatt ggcttcacaa ctaacgatgc ccaagcgaac
     9901 acttgataag atcttaaatg agttacgaga ggagaataaa gtcttctaca aggtaacacg
     9961 aggaagaaat ggcggaatga tcattgcttc agtcaaaacg ttgttcgcga gggttattca
    10021 actaagtaaa gaaaagagac tagattattc aacaaggatc acagaggtat ttggactcaa
    10081 cgagagctta gtagaagaga catttagaca attatcaacc cccttgaacc ctcttaaaga
    10141 agtgaatctt tttgaagtag atacaggttg aaaaataaaa ggtgcaaatt gccttataca
    10201 atatatctat gatacttctg taggtgttgc tccctttgcc tagctacgtg taggtggtat
    10261 acttataact gcgtatgcag tcttatgtat catggaggaa gttgtatgtc gttaaaaaat
    10321 tatgtctatt cacatcctgt taatgtgttt atcattggtc gtttgggatt atctgtggaa
    10381 gtgttctgtg agctttatgg ttttaagcag gggactttgt cttcttgggt taccagggaa
    10441 aaaacagttg cttctttgcc gattgagttt cttcatgggt tgtccttagc ttctggggag
    10501 actatggatc aggtatatga ttgtttgtgt gtgttagagc aggagtatat tgagtataaa
    10561 atagctaacg agttaagaaa aaggaagaag tatatccagt agtagttttt atttacttaa
    10621 aaaattggtt cattgagcaa cctatcgctg ctaaagtagc aaaggaaaac gttaaaggaa
    10681 agaatttagg gaagaaatcg aaatgaaatc ggacgactgg attgaacaca cctggcttcc
    10741 tctgaaaaga aatagcaaac gaaagaaatt ttgggtattg caattatggc cattaggaaa
    10801 actttgtagt tacggggcac gacttattct tgatttaacc gtttactcga ttggagtatt
    10861 tggaacggct tattacttga taaatgatcc caataggatt gcagcatcag acatttttac
    10921 agtgctaatg acgttgattt ttgtcatgct attgtctatt tttactcaat tagtcatgca
    10981 atttaccagg caaaaattaa cagcaggaaa acttttcaaa agcctattcg atttaattgt
    11041 tgtaaatgca attctagcga ctttaataaa acaaattgaa caatctggaa gaacaacaaa
    11101 aggagtgaag gattttttat tgacgtttat tcactttgta aatggacaca tgtatttgtt
    11161 tgaagtgggt attattctct tttttgtcgg gtatgtatcc acgaaactta ttaaacgttc
    11221 aattgaaaaa gaaattgaaa ttgacctgat tccgacactt cttggttatg agtacaatgt
    11281 tgattttgga agatatgacg aattgatcaa tacggatatc gttcacacga gtatccatga
    11341 atctactgtt aagggcatca gatctatttt aaaaaatggc caggaaatga aagcaataga
    11401 tcgaagaaaa gagatctaca atttttatga agtcgaagca agcctacgat atggcatcgg
    11461 aaaattgtgg ttagatggaa gtaatattcg tcaaaacaaa ccatacattt tttggaacag
    11521 tagtgattta gaacttccaa tgaaagataa ataattatgg agaatcgttt gaaaatgatt
    11581 cctctataca ggattgtgct tatagttggc atggagttaa aaaccttaaa gaaggagcag
    11641 ttattcaaag tgaaagaacg tcataatcag ttactatgta gtaaaacggg tacgatgaac
    11701 attgaatacc gaacagaata tttagaatta acgaatcaaa ctgatttttt gttgattcga
    11761 aagcaacaag agcaagaaaa aaattaatgg ctacttatag ccaattgatt gatgaatggg
    11821 aacaattcaa ggaatctaaa attccagaac gtctctaaaa gcctttattt gtaaagagca
    11881 taaggaaacg tgggaacact ttttaaaaaa agtgttccaa taggctgtgc ctattacgtt
    11941 tctcaaaaat aaatgtggga acaaaatatt taaaaatagg atagtgaaag gatagtgaag
    12001 gatagtaaaa ggagggtagt aggatagcaa aaaggatagg ctccttttcg ctatcctttt
    12061 taaattggag gaattaatat ggaagtaaga ataagaaatg tggatgagaa aatcgtaaga
    12121 gaaattgatc gaagatgtga cgaacggttc tgttgcaaag ttttaaatct actatcaaat
    12181 aaggtagaat aatagaaaaa gatagcagga ggaatgacga tgaatc
//
LOCUS       DAFENC010000067        10752 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.070, whole genome shotgun sequence.
ACCESSION   DAFENC010000067
VERSION     DAFENC010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10752
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.070"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            4..2376
                     /locus_tag="LP493_002538"
     CDS             4..2376
                     /locus_tag="LP493_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134649.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQKMTNGQ
                     PMNDKRNGRSWFNQQERIENKVQSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIENIPRIREEIERFEKGESSFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGEFEESKKYQATSEEEKVAVRELLEEA
                     APTDSLKEKENDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTLETPENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2437..3897
                     /locus_tag="LP493_002539"
     CDS             2437..3897
                     /locus_tag="LP493_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HBL2134650.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQIKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            3908..6112
                     /gene="topB"
                     /locus_tag="LP493_002540"
     CDS             3908..6112
                     /gene="topB"
                     /locus_tag="LP493_002540"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBL2134651.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLRAEEISTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTEATYES
                     LTPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGVLLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSIDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            6128..6277
                     /locus_tag="LP493_002541"
     CDS             6128..6277
                     /locus_tag="LP493_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134652.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKLRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            6352..6945
                     /locus_tag="LP493_002542"
     CDS             6352..6945
                     /locus_tag="LP493_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HBL2134653.1"
                     /translation="MQEKLKELLAIRDGNLSMKEARKLGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEIEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            6958..7857
                     /locus_tag="LP493_002543"
     CDS             6958..7857
                     /locus_tag="LP493_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HBL2134654.1"
                     /translation="MTPTQFAAKTRNLAKRTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTAQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIIGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            7860..8357
                     /gene="ssb"
                     /locus_tag="LP493_002544"
     CDS             7860..8357
                     /gene="ssb"
                     /locus_tag="LP493_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBL2134655.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMVTLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTTTFEQRDTATPNNNGLNALQNPFGNPFGGQSIDISD
                     DDLPF"
     gene            8723..8983
                     /locus_tag="LP493_002545"
     CDS             8723..8983
                     /locus_tag="LP493_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134656.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            9428..9634
                     /locus_tag="LP493_002546"
     CDS             9428..9634
                     /locus_tag="LP493_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HBL2134657.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGQRAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            9682..9885
                     /locus_tag="LP493_002547"
     CDS             9682..9885
                     /locus_tag="LP493_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134658.1"
                     /translation="MVDKEVISEKVAEALLIPRYWTIETPLVEDAPTMLFEDLVKIAG
                     YELHYQENMETYENEYWLTKLEN"
     gene            9901..10338
                     /locus_tag="LP493_002548"
     CDS             9901..10338
                     /locus_tag="LP493_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134659.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYGKFVETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            10331..>10752
                     /locus_tag="LP493_002549"
     CDS             10331..>10752
                     /locus_tag="LP493_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134660.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKHRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSCTICRKHYYSESEYYSIFESMELMEEEMEEL"
BASE COUNT         4063 a         1794 c         2251 g         2644 t
ORIGIN      
        1 gacatggcag aagaaaaaga accactagac aatagtcgtt tgggaaaatc caaaagaaaa
       61 ttagtacgat tgcaaaatga attaaatgaa caaatcgaaa agatgtttga acaccaaaaa
      121 atgacgaacg gtcaaccaat gaacgacaag aggaatggcc gttcatggtt taaccagcaa
      181 gaacgaatcg aaaataaagt ccaaagtctg agagaagaga tcaagcaaca agaaaaacag
      241 gtagaaaaac ttgaaagaca agaagagcta aaggaaatgg gttataacaa gtacggcgga
      301 ctagatatga cgatcgaaaa tattccaaga atcagagaag aaatcgaacg ctttgaaaaa
      361 ggtgaatcgt ctttttcagc cgccacgatc cgaaaatatc aacggaagtt ggaaacatta
      421 gaacagctga aagaaaaatc agaaaaagga aaagaaaata tcctccctga agtacaagcg
      481 atcattgaca gcggacgagt aacgcaatgg aaaaaaaatc cgaccattta ttttctgaaa
      541 ggctatcgaa aagtcgcttt agaactgaat gaaaacgggg aatttgagga atctaaaaaa
      601 taccaagcca catcggaaga ggaaaaagta gctgttcgtg aattacttga agaggctgcg
      661 ccaactgatt ctctgaagga gaaagaaaac gatcatttct atcgagtaga attcaacgaa
      721 aatgatccag aaaaaggatt gaaaagttat ggtggagaga tcgtaacatt agaattgatc
      781 gatcaactca aaacgttgga caaccaatac gctgcagaag caggttatta taaattctat
      841 tttgaagaag tgaagaacgg agaagtagtc gatcagatcc gaatggatct aggggatggc
      901 gtcaacagta atcaacccat ctatttagag ttagcaaaat tgtgcgaaca agtacctgag
      961 aaggaacaaa aacaatcggt caaaaatgaa cctgtttcga aagaacaaat gcagtcgaaa
     1021 gaaacaaaaa caaaacaaaa gggctatcaa aaacgaacgg cagaagagat taaacaagaa
     1081 gttaaatccc tttcgcaaca ggcactggat gcggtgaaaa agcataccca ttctcctgaa
     1141 gacgtcaaag aacttttgaa ctttatgtct cgttttccag aacgatcctt tagaaatcaa
     1201 ttattgattg aggaacaatt tccaggtgca acggcttgtt taggtcgtgc cgcgttgaaa
     1261 aaagaaggaa tctatatcaa aaaaggggaa caagggaaca agatctttgt cagaaaaacg
     1321 gtcaaagggt tttatgagaa aggacgtggc tttgttcgag aaacagaagc tacaccagaa
     1381 gataaaaaac gaatcgaaag tggtcaaatc gaagtgatca aaaaacctta ctatacgatt
     1441 gaaaaagtgt ttgatatcac acaaacacag ttaaaacctg aagactatcc gaaaatcttt
     1501 ccgaaccgtg tctttgattt tcaattggat aaaaaaggac agtcagaact tcaagctggg
     1561 attcaagcgg tagccaacaa tattggaata caaattcgag atatgacaga aagtgaagtc
     1621 tatcaaagag aattaggaca agcacgtggg gcgtatgttc gtaacgaatt tactggcgaa
     1681 gaagaaatcg tcatgaatac tcgaaatact cctacgcagc atttagctac aagtattcat
     1741 gaattagccc atgcaagaat gcacaaattt tcagaattag ataccgcaac taaagaattg
     1801 caggcagaaa tgacttctta tattgtgtgc aaacattttg gaatggacac gtcggagaaa
     1861 gctattcctt atattgcagc atggacgaag aatggtcaga cgttggatga taaggaagct
     1921 gcggaacgtg ggaaaatcat gaatgatgtc agccgtgtcg caaatgaatt cattcaaacc
     1981 atttctaatg aaatcaatca atacagagaa agagaaccag agatccaacc agcagaagtg
     2041 aagcaggagc ataaaaatac tttagaaacg ccagagaata agaatattgt gcccgttggt
     2101 tcactttgga tcgacaagaa agacgggaaa gtaatggaag aagatacggg tcgaacgtta
     2161 catttgaagg atgcggcgtt tattgaagat ccgcagcata atcaagtaat tttaaaagga
     2221 aaaagttatg gaaaagagat ccaaacggcg ttaccttcag aagaatttgc gctaggaaat
     2281 ccattccgat tttcacttga gacagtgtca gaagtggcaa aacgaaaaaa tgaaatctat
     2341 tatgaacaac aattgtcaca aaaagaacgt gtataaaaca agtaaaaaag actatctgaa
     2401 aaacggatag tcttttttct tttgggaggt tttaaaatga ccgagaaaaa aatgagtctt
     2461 attgatcgat gtaaacagat cgatatagtg gattttgctc gaaacaatgg aatggctgta
     2521 gtcaataaag gacgagatta tcgcttagaa gaccatgatt catttgtttt tgatcgaaga
     2581 aaacaacgtt tttattggaa cagtcaaaat attagtggcg acattattga attagctaaa
     2641 ctttttttca tagacaaaga gatccaagac cctaagcaac aatttaaagc agccactgat
     2701 tttattctaa agaatgaaga caaaacagaa cgagtggaaa atcttcattt tgaaacagaa
     2761 aagtacaaag atcaccccgt tgattatcaa ccactcacag aaaaaggaag gaattatctg
     2821 aaggaagaac gaaaactacc agagtggctg attgattatg cagaaaaaga agggttgatt
     2881 gccgaactaa agccaaaata tgaacggcaa aatttcttag ttcgagacga tcgtttagat
     2941 catgcggtcg cctttttatg gaaagatcca cagacaaaag agacagtagg ggcgagttat
     3001 caaggaacgt tcattgatta tgaacgtttt ggtgagagag gcacatataa gcatatagat
     3061 aaaaattcga cagcgaatca tggctttaac ctaaagatcg gtgaccctaa gcagataaaa
     3121 ttttttgaga gtagtattga tttacttagc tatgctgcac tgaatcgtga tcagttaaac
     3181 gatacgtggt tagtctctat ggaagggtta aaacaccatg tgatcagtca ttattttggt
     3241 gaggcagtat ctgaattgag aaagaaacaa gcctttcctc aatccatcga gatttgtgtg
     3301 gataatgacc gtgcaggaca tattttctac gaaaaagaac aattaatggg cgcagtcgat
     3361 ccatttacga atcagaaagt acgttgtgaa cgaggaatcg ctaatgattg gcaagtgcca
     3421 aaagaataca aaatcattta tgaagaagtc gcaaaagaag aaaaggtcac accagaagct
     3481 attatggcca tacacaagac agaaaacaat ctgcaattaa cgaaccaact ggtttccgct
     3541 cacaaagtaa atgcgttttt tggccagcag ctttctgtta acgattcaat agaagccatt
     3601 aatttgaaag atatttgtag agaagtcgca aaagaattaa aagtttgtga acgcgtggat
     3661 ggtacgtacg attttgatcg tttttatcaa gaaaaagggg atattaatgc gcagattctt
     3721 ttctcttata aagcagaaca atactacaaa ggctataaaa atcatgaaca tgaatttgta
     3781 cctgaagtaa aaaaggactg gaacgatcaa ttgaagcatg agatccagca acaagaaatc
     3841 agaaagcaaa aacgtgccat gttgtttcaa caaggcagac aacaagaaag ggagtgaaat
     3901 cgtcatgatg aaaaccgtta ttttagcaga aaagccgtca caagcgaaag cttatgccga
     3961 tagcttctct aaagccactc gaaaagacgg gtattttgaa atccaagatc gattgtttcc
     4021 tggtgaaact gtgatcacgt atggttttgg tcatttagtc gaattagatt cgcccgatat
     4081 gtacgatgaa aattggaaac aatggtcatt agaacatttg cctattttcc ctacacatta
     4141 tcactatcat gttcctaaag ataagaaaaa gcaattcaag gtggtgaaac agcaacttca
     4201 atcggccgac accattatta ttgcgacaga tagcgatcgt gaaggggaac tgatcgcttg
     4261 gacgatcatt caacaagtag gcgccgatca aggaaaaacc tttaaaagac tttggatcaa
     4321 ctccttagaa aaagaagcca tttatcaggg attccagcag ttacgagacg caaaagagac
     4381 ctatccaaaa tttgaagaag cacaagcacg tcagatcgcc gattggttaa ttgggatgaa
     4441 cggtagccca ctgtatagtt tactcttgca gcaaaaaggc ataccaggaa gcttttcctt
     4501 aggcagagtc caaaccccaa cgctttacat gatttatcaa ttgcaggaaa agattagaaa
     4561 tttcaagaaa gaaccttatt ttgaaggaaa atccgaagta atcgctcaaa atggcgcatt
     4621 tgatgcgaag cttgatccga atgaaaccca agcgacgcaa gaagcatttg aagattattt
     4681 aaaagaaaag ggggttcaat tgggaaaaca gccaggcatg attcgccaag ttgaaaccga
     4741 gaaaaaaagc gcggcaagtc cacgtctttt ttctctatcc agccttcagt ctaaaatgaa
     4801 tcagctcatg aaagctagtg ccaaagacac tttggaagcc atgcaaggct tgtatgaagg
     4861 gaaatatcta agctatccgc gaacggatac cccttacatt acggaagggg aatatgcgta
     4921 tctgttggat cacttagacg aatacaagca ttttttgagg gctgaagaaa tttcgactcc
     4981 tattcataca ccgaatagta ggtacgtgaa caacaagaaa gtccaggaac attacgcaat
     5041 cattcctaca aaaacagtta tgacagaagc gacgtatgaa agtctgacac ctttacaaca
     5101 agcgatttac gagcaagttt taaaaacgac agtggcgatg tttgcggaaa aatataccta
     5161 tgaagaaaca acgatcttga cgcaagtcca gcagcttcag ttaaaggcaa tcggaaaagt
     5221 accgatagat ctaggttgga agaagttatt tggcaaagag agcgacggaa aagagaagga
     5281 agaagagccg ctacttccta aagtgacaaa aggagaaatg gtgacggtag atctacaagt
     5341 ccttgagaaa gaaaccaagc caccacaacc ttataccgaa ggtacgttga tcactgcgat
     5401 gaaaacagct gggaaaaccg tggatagtga agaagcgcaa tccatattga aagaagtgga
     5461 aggaatcggt acagaagcga cacgggcgaa tattattgaa accttgaaac aaaaggaata
     5521 tatcaaggta gagaaaaata agcttgtggt gacgaataaa ggggttttgc tttgccaagc
     5581 tgtggaaaaa gagccgctgc ttacgagtgc cgaaatgacc gccaaatggg aaagctactt
     5641 gttaaagatt ggagaacgaa aaggaacaca aaccactttt ctagccaata tccaaaagtt
     5701 tgtctctcac ttattggaag tcgtcccagg acaaatccaa tccattgatt ttggatcgac
     5761 gttacaagaa gtgaaagcag ccagtgaaaa gcaagaagcc gcgcgtcatt taggaatttg
     5821 tccaaaatgc caggaacaag aagtcttact ctatcaaaag gtggcagctt gtacgtctga
     5881 agcctgtgat tttaaattat ggacaacgat tgccaaaaag aaactcacag cgacacagct
     5941 gaaggagatt attcaaaata gccgaacaag ccaaccagtg aaagggttaa aaggtcagaa
     6001 gggttcgttt gaagcaacga ttgttttaaa agaagacttc actacaggct ttgaattttc
     6061 tgaaaagaaa aaaacgaact tcaagaaaag aacacgacgc acgacaaaat aatggagggt
     6121 taatcttatg cgtaatacaa cacacaaaca acaagaaatc gaaaatcaaa aagccaaaat
     6181 tcgttcagaa caagagaaat tacgtgccag taaaagaaga cttcagcaat taaagaacca
     6241 gcaacggatt caaaaagaaa tcgaattaga tcgatagaca ttaaccttgt tacaaataca
     6301 ctatcatgat atatttaatg tagtgtattt gtaacaaaag gggggaagta aatgcaagag
     6361 aaactgaaag aattgttggc tattcgcgat ggaaatttat ctatgaagga agccagaaaa
     6421 ttaggaatcg cagcaaccac tgtacaaaga ttggtgaatc aaggaaaatt gatcaaagtt
     6481 gatcgtggtt attatgtaga ggatggtcat ggaatagatg atttattttg gcttcagcaa
     6541 cgtttttcca ggggaatctt ctctcatgaa acgactttag atatttacca gctttctacg
     6601 aatatgccga aattcattca cttaactttt ccccatggat ataacgttga tcgttcaatt
     6661 acaaaagagc agcagttaca atttcatttc gtgaagaaag aagtttatga actaggaaaa
     6721 gtagagggaa cttcctttca aggaaatcct attactatgt atgataaaga gcgtacactt
     6781 tgtgatattt ggaatccgag atatgaaatt gaatatgaaa tgaaattaga agcattaaaa
     6841 gagtacatgg aagacccatt gagagatcca agtaaattaa gagattacat gacaaaacta
     6901 catgtagaaa aagaaatgaa ataccacatg caaagcttat attgatggag gaaaaagatg
     6961 acaccgacac aatttgcagc aaaaacaaga aatttagcaa agaggacagg attaaatgca
     7021 cagttagtac aacggcattt tatgatggat cgtttaattg aacaaatttc tgaatctaag
     7081 tataaaaatg atttcatttt gaaaggtggc tttttattag gatcaaaata tggaatcgat
     7141 agaaggacga caattgatat cgacacgaca tttagaaata gcaaattaac tgaagaaaaa
     7201 ttgaagagta tttttaatga tttaactagg aaacccacga aagaaggtat tgttttctct
     7261 attcaaggaa tgaaggaaac aagagaagcc gatttttatc ctggatttca aattaaattg
     7321 gtggctaatt tagagaaagt acgtgtgcca tttaaaatgg acgtgacaac aggagattct
     7381 atttatcctg aagtagatac acactatcac caattaatgt ttgaagataa aaaggtggag
     7441 attccagctt atccaacagc acaaattatt gcagaaaagc taagtgctac gttcagcttt
     7501 ggcacagata attcgagagc aaaagattac tacgacttat ttaccattcc gaaactagaa
     7561 aatatcgata cgaaagagtt atacaaaagt gttcgaaata catttacaaa acgtggggat
     7621 acaaaaccgt tgtcctttta ttatgaaaga gaaatggata agatcatagg aaatgactat
     7681 ttggaaaagc agtgggaaaa atatcgctca gttaacacgt ttgcgaattc catttcattt
     7741 acagatacag tcaacgaaat tgatcaccta atgaaaagtg tgatcaaaat tgaaaatcaa
     7801 gaaagaaaac ggcagtttaa aagatcacaa caaatgaatc aagaaatgga gagataaaga
     7861 tgatcaataa tgtaacttta gtaggacgct taaccaaaga tccagattta cgttataccg
     7921 cgagtggtac tgcagtagcg acttttaccc tagctgtcaa ccgaaatttc acgaatcaaa
     7981 acggcaatcg agaagctgat tttattaact gtgtgatttg gcgcaaacca gcagaaacaa
     8041 tggtgacatt agctaaaaaa ggtagcttga ttggtgtagt tgggcggatt caaacgcgga
     8101 cttatgacaa ccagcaagga caacgtgtgt atgtgacaga agttgtggcc gataatttcc
     8161 aactattaga aagcaaagca gcgacagaaa gccgtgcgca cgctgatcaa tcgtccacca
     8221 gtccaagcac caccactttt gaacaacggg atacagcgac gcctaataac aatggattga
     8281 acgctttaca gaatccattt gggaatccat ttggtggaca atcaatcgat attagcgatg
     8341 atgatctacc gttctaagta gcattttcta ttggttgcat ttgctacggt ttatgttata
     8401 atttagtcaa caaaaagaat tttcaatcta taaccaaaaa ccactagctg gcgggctagt
     8461 ggttttcttt tacgtttcta ttataagaat taacgggtag gcttactgtc tttcttggca
     8521 aatttacaat caagccattt gcagatatag tgcgcggcta cttctgccat gattgcaaaa
     8581 acaaaatcaa aaagaatttt caaacctata acctcctccc cttgccagat taggccgggg
     8641 tagcagacag caagactatt atagcataat tgaaatatcc aaatgattgg atttttgcta
     8701 taattttagc gaggtgattg tgatgaacaa atatgttggt ttgcttgata aaatccgagt
     8761 aataaaaacg caaccgttat tggttcgctt tactttacaa acgattcatg aatcgattaa
     8821 ttgtgtagtt gcagatattg aaattatcga taaattgcta attatggatg atggaaaata
     8881 caatattgcc gtcacaggtc acttcaataa acgaaatcag ctagttattg ctagcatgta
     8941 tgttagaaat cccgatcatt ttacgcgatc gatgggcata taaaaaaaga agagttgcaa
     9001 tcctaatgta ggactgcagc tctttttgtt ttacatagaa acaagaaaaa tgaaaaggcc
     9061 tttttaggaa ggcgcgagcg ccttctcaat tgaaaaacct ctctcactcc aaccgccacc
     9121 gccgttcgag aagaaaggaa gtgaacgttg cacgttcact aagataaagg gtcttgcaaa
     9181 gcaagacaaa atagaaaaaa cttcctctca ccaaaaggtt cgttcctgtt cgttatctct
     9241 ttattgattt gccagaccgg caacaagttg ccttttatca ccaaaaagcg acaaggacaa
     9301 gggtaaatgg cacgctgcgc gcccttgtcc ttgtcgcttt tcgttgattc attctggcca
     9361 acaaatcaat aaagaaagaa ctaacgaaag gaagtaaaac ctttcctaag aggaggcaga
     9421 atcaatcatg cgaaagaaat ttgattattg gggtgttccc ttcagcgaat tattcccaaa
     9481 ctatcatgca ccacatactg tcgaatgcga ttgtggacaa agagcgaaat gtatcaaaag
     9541 ctatcgtttg tatcaatgtc caacatgcgg aaaaaaatac accttgtctt atggcgatta
     9601 tattttgatt gatgagaaag gaaagaaacg ctgatgaaaa cataacataa attattgact
     9661 gtaaaagaag tcgttcaaat tttggtggac aaagaagtca tttctgaaaa agtagcagaa
     9721 gctttactta ttccgcggta ctggacgata gaaacccctt tagtagagga tgcaccgact
     9781 atgctatttg aagacctagt gaagattgca ggatatgaac tgcattatca agaaaacatg
     9841 gaaacttatg aaaacgaata ttggttaacc aaattagaga actaaaaagg agaaaaaaat
     9901 atggctcaaa attactatga cgaatttgtc aaattacctt tggataaaat ggcacaaaaa
     9961 atggaggata tgacattcct ataccatgag acacgtgttc caaaaaaaca ttataaggaa
    10021 agattgtcgg tagctgtgga agaaatgatt gaatcaggtg tcgaaatgaa tctcattgcg
    10081 acgtactatc gaacactgga agaactgaaa aaacaaaatg caaaatggtt tttccaagcc
    10141 ttactatgct tggaagtagg tgtcaaacca agcactatta aaccttctga atatcaagct
    10201 ttagaactaa cgtatgggaa atttgtcgaa acgaaaaaag ccaagactgt ttcaagtgaa
    10261 tggttagatt attttgaaaa tatcaataag tatggcgcct attacaccat gaaaaaggag
    10321 gacaacgaaa atgaataagg tgatttatca actaacaacg gaagatgtgt cacacttttt
    10381 aacaaacaaa gaacatttga atgaagtaat cagacggatt caaaaagact ttagttgtat
    10441 ggaagaaatg aagtacttta ttcaaagagt cgaagaacaa ttgtatttgg aaagtgaaac
    10501 gagtcaaacg aaggttacag tcagcaataa ttatttagac gtgtataaac atcgtcctga
    10561 aacggtaaaa aaaggaacgg agcttctacg actagaaaca gaaaaataca tcatgaatgt
    10621 ttacctagaa aggagtgaac tggtcgaaaa ctttgtcagc tgcacgattt gcaggaaaca
    10681 ctattactca gaatcagaat attattcaat ttttgagagc atggaattaa tggaagaaga
    10741 aatggaagag ct
//
LOCUS       DAFENC010000068        10454 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.071, whole genome shotgun sequence.
ACCESSION   DAFENC010000068
VERSION     DAFENC010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10454
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.071"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(559..1599)
                     /locus_tag="LP493_002550"
     CDS             complement(559..1599)
                     /locus_tag="LP493_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBL2134661.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     LMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(1948..2274)
                     /locus_tag="LP493_002551"
     CDS             complement(1948..2274)
                     /locus_tag="LP493_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134662.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(2261..3064)
                     /locus_tag="LP493_002552"
     CDS             complement(2261..3064)
                     /locus_tag="LP493_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBL2134663.1"
                     /translation="MGDILMARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVD
                     IDPQGNATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAERE
                     FTQVGSEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLK
                     GLIKLSETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKT
                     YIRRTITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(3417..3707)
                     /locus_tag="LP493_002553"
     CDS             complement(3417..3707)
                     /locus_tag="LP493_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HBL2134664.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(3843..4022)
                     /locus_tag="LP493_002554"
     CDS             complement(3843..4022)
                     /locus_tag="LP493_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134665.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(4019..4369)
                     /locus_tag="LP493_002555"
     CDS             complement(4019..4369)
                     /locus_tag="LP493_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134666.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(4362..5687)
                     /locus_tag="LP493_002556"
     CDS             complement(4362..5687)
                     /locus_tag="LP493_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBL2134667.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
     gene            6137..6751
                     /locus_tag="LP493_002557"
     CDS             6137..6751
                     /locus_tag="LP493_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2134668.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(6916..7920)
                     /locus_tag="LP493_002558"
     CDS             complement(6916..7920)
                     /locus_tag="LP493_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134669.1"
                     /translation="MEYKFNLNLKEVLPTQGTININGQDNDDDIVIKKIEFIDSDINV
                     FFYSKEKLADFSNIAEMIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLE
                     LKTLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITA
                     CEIGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEK
                     RNKLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNK
                     SQITLSKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD
                     "
     gene            complement(8379..8636)
                     /locus_tag="LP493_002559"
     CDS             complement(8379..8636)
                     /locus_tag="LP493_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBL2134670.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(8629..8898)
                     /locus_tag="LP493_002560"
     CDS             complement(8629..8898)
                     /locus_tag="LP493_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBL2134671.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(9029..9208)
                     /locus_tag="LP493_002561"
     CDS             complement(9029..9208)
                     /locus_tag="LP493_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134672.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            complement(9589..10155)
                     /locus_tag="LP493_002562"
                     /pseudo
     CDS             complement(9589..10155)
                     /locus_tag="LP493_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            10231..>10454
                     /locus_tag="LP493_002563"
     CDS             10231..>10454
                     /locus_tag="LP493_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBL2134673.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWK"
BASE COUNT         3210 a         1894 c         1518 g         3832 t
ORIGIN      
        1 cgttgcgggt aataccgtaa cactgaaggg cacgcattaa ggcgtcatct taatgctttc
       61 ctgtaggaca ctgacggaga ttaccagtct cccgagcctt acaggggcct ttcttttttt
      121 tgtattttca attatcacaa tttatcgtcc aaaagtgcag aacgaaaatc aattcatcac
      181 aagcatatca gacaattaaa tttaaaacaa ctaaaaatat acaaaaaagt gtaattgaat
      241 attagcagca ctgcctgaaa agaagtaata tcaggctttt cagcttgggg aaataagtga
      301 attacctctc ttcatgaatt attataactc aaaaaagcac atatgcaaac actagttccc
      361 tatttttttg aatgaaaaat aactaaaata tctaacgatt atgactttaa aacctacgtt
      421 tgtgattgtt ttcataaact tttaatctaa aaactccgga ataatagcta tttatttgta
      481 acatttgtaa taaaattaaa atcataaaaa agttctaatt taaaattgat catttttata
      541 gtgatcgctt tttatcaact actctagcca attttccgta ctaactgttg gtaattcgtt
      601 aaatgtttct ctttgttcgt ttgcaagctt tgccgcaata gctttttcga caaaccaatt
      661 ttttacataa acgaaaatta gattctgcaa attgtttact ttttcagttt tttgtttttg
      721 ataagctttc agcaaagtca tatataatcc tttgtcagca tcaattccat aagattccag
      781 ttcttcataa acaacaactg tttgctctaa ttcttcagct tttttctttg cattatgaat
      841 agtttggacg gttttttgag cgtcttcgta agtactagaa aatgttttta tcaagtttaa
      901 tacattttct ggtacaaatg tatttatact gtcctctttc atgaggtcga cgaagttatc
      961 tagtaaaact tgattttgta actgatcagt ttcagtgtct attatgtgtc tattagtgtc
     1021 tatagaatta gaatagaata gattgtctgc gattttcgca attacggttg agtccttgat
     1081 atgactggat tttgccgtat ttgcgatttt cgcaattacg gtggtatcat tgatttctcg
     1141 cggttttgcc gtatttgcga ttttcgcaat tacggtggta tcagtattgt cttcctcttc
     1201 catgatttta aagacgtctt gattcgttac ttctggcttg cctaagtaca ataaattagg
     1261 catggattca atcttaccgt cacgtttatt tactcttcct ctcttctgtt tcagaagacc
     1321 tgctttttct aattcctttt tgattttaga tactttacct tcgcggcatt gtaacaattt
     1381 cattaattct tcaactgtga atatgaaaaa tatattatca tcagaatcta cccagttatt
     1441 tttgactgaa taatcaaatc gatctttaag tagcatataa gcaatttttg catcatttga
     1501 tagatccatg tatttttcgt tagtaaaaaa taccttaggc atttgataat atttttcacg
     1561 ataaatttct tttgatttgt aataattaaa atcattcata gccaatcctc tttctgtagg
     1621 atagcgtttt gttcaaaact atgttacaat gaattaaaca aatatatcta tccactatat
     1681 atttttctac tgctgataag tcgccaaact ttgttaaagc agtagtcttt ttttatcttt
     1741 ttttagttta ccttaaaaaa taaattaaag caaaccgctc tatttcaagg tttaagctca
     1801 tagtaactat atcacgatat tacaataata ttatatcacg atatcgtaat attacaatat
     1861 gaagataagc gacttatcag ctttgatact actgattttt ataaaaaaaa tatcacgata
     1921 ttatgatatc gtgatattga atgtaaatta aattttattt tgtttctttg ctagtttata
     1981 tccttcaatc aagtattctt caggtatgga ctttaatagc gcatcttcta taacgtctgg
     2041 tttacttttg tctgattcag caatagtcgt ccaatatttg agtgctgaca ttagaattgg
     2101 atttatacga atgctatctg ctgttcttac actacttcct tgatctttta tgactttact
     2161 tatatttttc ttggttaatt cgatttcttc tacttctttt gatttaaaat tctttttatt
     2221 tttatttcct agtaatctac ttactgcagc ttgactgcga ttatcttctg ccatcaaaat
     2281 caccaacttc ttttaaatat tcttctgtaa atgctttata gtcatcttca gctgttgagg
     2341 gtttattaaa attgattaga tctgatccag cagcttgcgc ttcgtcaacg gttattgtcc
     2401 tacgaatata agttttgaaa atttttgcac caatgactct agaaatttcg gttgctgcag
     2461 acgtcatttc tttagaaatg ttataacgct tattatactt agtaaataga actcctcgta
     2521 cttcaagctt gtcgttcgta tattctttta ccgtttcaat agtttcactt aactttatta
     2581 gtccttttaa tgagaaatac gcagcttcaa ctggaatgat aatttcatca gaaacagtaa
     2641 atgcgttgac tgtaagcatt cctaaacttg gtggacaatc aattataata taatcatagt
     2701 tgtccttgat tggttgaagt actcttttaa gcctgtgttc acttcctact tgagtaaatt
     2761 ccctctctgc agaagaaagg gctatgtcgg ctggcaaaac atcaattcct ttatagtcca
     2821 gaatagcatc tgtaatgtca gcctcccctt ttaatacttc ataaattgta ggttggtttg
     2881 ttccatctat atcgaaacct acattatctg tagcatttcc ctgaggatca atgtccacta
     2941 aaagtacatt tttaccgtaa acaaatttca aacatgctgc taaattaacg ctagtcgtag
     3001 ttttagaaac tccacctttt tgattggcta ctgacaatat tcttgccatt aaaatatccc
     3061 ccattcatct tatattataa tataattata tcataatatt gtgatattgc aatatcgtat
     3121 atgcattata ttgtaatatt gtgtgattat tttgttttaa agatatatat cggttcggat
     3181 ataaagatta ttcatatgtt attcgaaatt aaaataatca ctttttatta ctttaaaatt
     3241 ttttattaat gataagaaat atgttttgcg agcagcaact agaataattt aaacattact
     3301 aaactgtcta tattgttact aataattccc ttcttatagt gcattttctt agaaaaaaac
     3361 aatattacga tatcatgata ttaagatatc gtaatattat acaattgtga ttgatattat
     3421 atatgttttt ttattttttt atcatgttta atcttgaagg aatcatattc tttttctaaa
     3481 gacaggagct tttcataaac atcagacatg tttaaactag aggccaggct taaatcataa
     3541 acgaatgaag caggtaatga ttttattcta cgttgtcggg ttatccagct tgcaaccgtt
     3601 ccttgtgggt aggcatataa ctcacaaaat tgttctacag tgattcctaa attcttgata
     3661 atgtaaacat tgatcgggtg cgagtaaaca aatgtattga tagacatggt gcgtaagcct
     3721 actttctttt attattgcgt ttgcaataat agtttaacac acgcattatt ctagtatcta
     3781 ctcctatttg taaaaacaaa aaaggattca tagagataac tctatagaat ccgtaaaata
     3841 ccttatatat ataacgggaa gatataaaac ctaaaattat gataacctgc tgcagcttct
     3901 acatagaaag agaagcgctc aacaccaacc tcatttatca aacgttggcc ataaccccaa
     3961 atctcttctg atagctgatc aaaggttata tactttagct catattgctg gataatgttc
     4021 attctaatcg actccattta ttatcctggt aaaattcgat atgacgtatt tcgtcgtagt
     4081 gaattttgtc ttttccaacg tagatcccca gctcatcact acctaagatc ttgccaatga
     4141 tatcttctgg atagtatcct tcagcgtttc gttcttcttt ttgaatagat actgatctat
     4201 tttttatgac tgcagcgttc aatacttccg caatctcttc agtcgtcatt tgttcttttg
     4261 ctaaattttg actggttcgt tgttcattgt cggcatcaat ttcttcagta tgatcagata
     4321 aataaaaccc tgcccacttt aaacgtccac gatcattgta atcaatcatt tttaattccc
     4381 ccatttccgc ccgcatgacc accaacaagt gtgcttctag taatgcttct agcgccttct
     4441 aacattgaag aagcatgtac aatcgacgta aaaccatatt tttgccgaat cttgtcaata
     4501 attttatcta aattttcttc gtcaatttgc ttttgtggat cactaaataa atccagctga
     4561 agcgaatcgg tgtacacaag cttgctatag gttattccaa catgccttac ttcttgtcct
     4621 tcataatact tatcaaacaa gaaaagacaa taattctgca attcctttgt attatctgtg
     4681 atagggatct tcatctggtg tgaaaaccct ggtctcgttt ctaagatcga cgtgccaatg
     4741 tgtaaatgga cacaacctgt tttacagtta tgctgcctaa tgcgtatcgc tacttgttcc
     4801 gccatttctt ttaccaccag ctcgatttca tttcttctag tataatctcg tggtaacact
     4861 tgtgaatttc catatgattt ttcctttgtc ggttctggtg ggattgctat atctgttcga
     4921 tcgatcccat tagcatggaa gtacagctgt aagccaatca cacctagtct attcttaatc
     4981 gtataaggat tccagttagc aagatctcta atgctcataa tccccatctg attgagtctt
     5041 tttttcattc gagagccaat tccccaaaag tccgtcattt caggaatatt ccatactttt
     5101 tcaggaacgt tttcgtacgt ccattccgca acaaatcctt cattatgctt tgcttcgttg
     5161 tctaaggcta gtttagccaa aaggggatta tctccgacac ctactgtagc aatcaatcct
     5221 agctcttctt taatattctc ctggatcatt tgagccagct tctttctccg ttgacttcgt
     5281 gttccttcag tcgtaaaaag attcagtgat cgggtcactt ttaagattga ttcatcgatc
     5341 gagtaaatca gtagatcttc atcagccaca tatcttctga aaatattatt tacctgcata
     5401 tttcgcttga tatataggtt catacgtggt ggaacaacgt gtagtgtttt aggaaatggt
     5461 tgtggtaagt cacgtggtct actcacattt gtaataccat accgcttttt tgcttcagga
     5521 gaagaagcta atatcaatcc tgaaccagta ttatcagctc gactcataac aacaagttct
     5581 gttgttaatg gatctaaatt tctttctata cattcgacac ttgcgtaaaa gcttttcata
     5641 tcgattaaaa agtaatcatt tactggctct tttgaataat ccatcataaa taacactcca
     5701 ttctttcaca ttatacaaac atatgttcga tattgtaaag aagaaatagc taaatacata
     5761 aaaaaagaag cataggtatg ctatcaccct gcttcttctt ttgatttgta tgatcaattt
     5821 attctatcac tttactaatt aatttgaaaa tctaataaaa actctcactc taaaagagtg
     5881 agagactgca aattagagta cggacttttt tggagttccg ttctttaata ttaacaaatg
     5941 aataaaatcc ttacaacatt tgagaataag ttatcagtag acacttacaa aaaattctca
     6001 tactatttcc tccatcatta gtttttgtct atataaggtt taccctaaat agacactggt
     6061 ataacattga aaaatatggc ttcctcgtgt atgattaggg tgtattttaa atagttgcag
     6121 aaagtaggta aaagttttga gagttgcata catacgtgtc tcatcgatcg atcaaaatga
     6181 acaacgccag attgaagaaa tgaaaaaatt cggtgcagag agaattttca tcgagaaaca
     6241 atctggcgca acgattactc atcgacctgt tttccaagaa gcattagatt acgtccgaga
     6301 tcaagatatt tttattgtgg aagctattga tcgacttgga agaaattatg acgagatcat
     6361 cgcttcagtc aattacttga agaagaaaaa tgtgaagctg atcattacta gtttaccgat
     6421 catggctgaa gcaattggca atcctctcct ggataaattc attaaggatc tgatcatcca
     6481 aattttggcc atgatcgctg aacaagaacg gactgaatcg aaacgtcgcc aggcacaagg
     6541 aattaagatc gcaaaagcaa acggcgtcta caaagggcgg cccaaattat acagtgcaga
     6601 cgcaaaagat ccccaacgtc gccttgttta caaaagcatc gttgaagatc ttaaaaatgg
     6661 tgttgcgatt gctaagattg ctaaagacta caatgttacg agacaaaccg tgtatagaat
     6721 aaaaaaagac agcatggtca atgacaaata gttgatcatg ctgcttttat tatcttctca
     6781 tctttaattt cctacatata attactatct ataaaattaa gtcttactca gaacagataa
     6841 agcataaaat tccaacaaac cattttttac ttaactaaat aaagagtctg ttaatataat
     6901 cttcacttat ttacgttaat cccctactgt atttgttggt tccttatcta tattttctac
     6961 aaaatcctta ttatcttgtg atttagcttc gtataattct ttgtatgtcg acacattggt
     7021 tatactaatt cctatagcta gttcttgaga ctctactttt ctctctagct cctttgacaa
     7081 agtgatttga gatttatttg gttccgttgg agtcaattct atagattctt cataaaaatc
     7141 tctatacata aagctatcat taattttata aaaaaaatta aatgttttta gcactgccat
     7201 ataacattca aaacattctt ctatagttgg tttacttcct tgaggagaat gaaccaattt
     7261 attacgtttt tctatgaaat ttttaatttc ctttcttatt tctttcggaa actcaatatt
     7321 aaagtaccct ttaaacatgc tccctaataa tttgtctaca gggggagatt gtaaattctc
     7381 aaatattaga gttaaatcag gtttctcttg ttgataaaat tcctttaccc ctatttcaca
     7441 ggctgtaatt atcgaaataa acctatctct agtatttgat atatttttac ttcttttaag
     7501 gagtataaga gaaaagggga tactttcgtg tccatgcatg taattaacta attgttgagc
     7561 ttcagaagtt atatctctaa ttatatagtt aacggaatta ggaagtgtct ttaactctaa
     7621 tgaaatttct atccaattac tatcttctaa tctgtatatg ctcgaagtat aatttgattc
     7681 gtcagcaagc atcgctacat cccaaacact gatcataaaa tcttttaaac gttcaatcat
     7741 ttcagcaata ttgctaaaat cagctaattt ttctttagaa taaaaaaaaa catttatatc
     7801 agaatcaata aattctattt tttttattac tatatcgtca tcattatctt gaccatttat
     7861 gtttattgtt ccctgagtgg ggagtacttc tttcaaattc aagttaaatt tatattccat
     7921 tacttctcct ccaatatata aaaattactt aactgtatcc aaatttaata tgtaaataaa
     7981 tcattaattt ttagctaaat tctatgagaa gtttattttt gttgtttttg ctaattaact
     8041 aaaactagta caaaaaattt aaaatagatt attaaaccta ttgcttattc tattcagtca
     8101 tatatataag cgtcatcctt tagtaactaa catcccacac tacaatagta ttataacata
     8161 tctattcaac ttcaaattgt tgaaatttaa gccatttata tttacttttc ctcaacttta
     8221 gaaatgattt tactaacctt atatccgtaa tacgcgtaac aaacacattc attaataaca
     8281 atcaacacta agctatatta gctttttaaa tgactagggt aaataaaata aggatcaaaa
     8341 acttttaagt ttctgaccct ttccttactt ccgattggtt aatagtgatc ttttgcagaa
     8401 taaataaata tcgtttcatt ttcaactcta tatatcagtc tatgttcatc tgtaattctt
     8461 ctggaccatt ttccagataa atcatgcttt aatggctcag gttttcctaa tccagcaaag
     8521 ggggaacgat cgatatcttt tattaacttg ttaatctttt ttatattgct tttgtttcct
     8581 tgctcatgcc aataaagata atcatcccaa gcatcatcag accaagcctt aatcatcaga
     8641 ttcaacctcg attaagtcat gtgttttaaa tgcacctttg gagaattgtt catctcctcg
     8701 acgaattttt tccatgacgt aattattaga aagtgttctc aacgtttctt gcatagaatc
     8761 ataatctctt tttgataata caacaactgt atcttctaca tctttacttg ttacaataag
     8821 tgtttcagca tcctcattaa cttgtttcat ataactacgt aaattttggc ggaaatttga
     8881 ataagctact gcttccattc ctttcacccc ttatttattt ctataaaaca attgtacatt
     8941 atattgtaca attaagcaaa tgattaatat tctaacttct tataattaaa agtgctatca
     9001 cttttagttt ttaggataaa aagtgacgtc actttttgag tgctggtacc tcaaatcctg
     9061 ctttttcttg ggcaatcaat aaatctaacg caatacacat aatcctggat tcacttttgc
     9121 cgtacttctg ctttagttgc tgcaattctt tttgtctctt ttcatccaac gtaacgggta
     9181 accgtttatt tcctattgca attggcatta gtactctctc ctttcatcga aataacccta
     9241 tgaaaaatat ggctgcaatc atcttgaata gtagactcac aagggctaat acaaagcgcc
     9301 aaaagatcaa acaaaatacc agtattgcca aaaatactac gaagtttaaa tgcacagctg
     9361 cagcatggcg cataagtatt tcgccaacaa ataggactaa caatagagga atgattttat
     9421 tcatatggat ctccttcttt ctcttaggtt atcgggtgtt gcccgcttat ttcgcaccac
     9481 ctaagcggcg ggggcggttg gagcgattgg tgcgaaataa gaaccattcc cttagttact
     9541 aggttttttg tccttatttc acacattctc acttttcggt ataaatgatt attgcctttt
     9601 tttcctttca aatcgttgat atggcattcg tttacggtca agttcatttt ggatttcttc
     9661 tgtatcgtcg taagtatagg tgtctaaaaa atcagttaaa gtcgtgtacc agtcgtcgcc
     9721 tgggttatct acttcttcta catattccct caaaaatgct tcgggtacag cgagttcata
     9781 atccattccc attaacacga tagattccgt tccacacgtc aaaaatctag taaatacaag
     9841 gtaataatcg tctatcgtcg catctttgct gtttagctct tccatttctt cttccattaa
     9901 ttccatgctc tcaaaaattg aataatattc tgattctgag taatagtgtt tcctgcaaat
     9961 cgtgtagctg acaaagtttt cgaccagctc actcctttct aggtaaacat tcatgatgta
    10021 tttttctgtt tctagtcgta gaagctccgt tccttttttt accgtttcag gacgacgttt
    10081 atacacgtct aaacgattat ggctgactgt gaccttcgtt tgactcgttt cactttccaa
    10141 atacaattgt tcttcgggtt ctgttgcaaa gttttaaatc tactatcaaa taaggtagaa
    10201 taatagaaaa agatagcagg aggaatgacg atgaatcatt ttaaaggaaa gcaatttcag
    10261 caggatgtga ttattgtagc cgtgggctac tatcttcgtt ataaccttag ctatcgtgaa
    10321 gttcaagaaa tcttatatga tcgtggcatt aacgtttctc atacgacgat ttatcgttgg
    10381 gtgcaagaat atggcaaact actctatcaa atttggaaaa agaaaaataa aaaatccttt
    10441 tattcatgga aaat
//
LOCUS       DAFENC010000069         9992 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.073, whole genome shotgun sequence.
ACCESSION   DAFENC010000069
VERSION     DAFENC010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9992
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.073"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..253)
                     /locus_tag="LP493_002564"
     CDS             complement(<1..253)
                     /locus_tag="LP493_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBL2134674.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWVQEYSKVLYYLWKKKNRQSFYSWKMDETYIKIKG"
     gene            complement(327..977)
                     /locus_tag="LP493_002565"
                     /pseudo
     CDS             complement(327..977)
                     /locus_tag="LP493_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631195.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
     gene            1302..1718
                     /locus_tag="LP493_002566"
     CDS             1302..1718
                     /locus_tag="LP493_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBL2134675.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIKESQQSVIDCRKLLVEQLTGGDDL"
     gene            1715..2185
                     /locus_tag="LP493_002567"
     CDS             1715..2185
                     /locus_tag="LP493_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBL2134676.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            2199..2972
                     /locus_tag="LP493_002568"
     CDS             2199..2972
                     /locus_tag="LP493_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2134677.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAAAPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            2986..3798
                     /locus_tag="LP493_002569"
     CDS             2986..3798
                     /locus_tag="LP493_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBL2134678.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            3852..4817
                     /locus_tag="LP493_002570"
     CDS             3852..4817
                     /locus_tag="LP493_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL2134679.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAAKLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLDYFNPFVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            4933..7656
                     /locus_tag="LP493_002571"
     CDS             4933..7656
                     /locus_tag="LP493_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBL2134680.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLSSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESKILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQEKKTKDQLNEFFANVL
                     ETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSLNVTNVKTGIKSIVLAHGYSTA
                     SSMANVANRMLNKNVFQAYDMPLDITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQ
                     LGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPK
                     KKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQL
                     YDVIMIVGTEDPKINQIPYIGLDRLINGEAIGEFVHYLEKELTIEVNDLQKELIFNFS
                     ISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKE
                     SVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            7669..8301
                     /locus_tag="LP493_002572"
     CDS             7669..8301
                     /locus_tag="LP493_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBL2134681.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKDLRKEVKPLLDFLKKRDIP
                     LALASSSPVVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTVALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            9200..>9992
                     /locus_tag="LP493_002573"
     CDS             9200..>9992
                     /locus_tag="LP493_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2134682.1"
                     /translation="MKNLQLKFIVDPSIVRWFRIINQFERNQLATKGELAKSNHVSER
                     TIQTDVNKMKDYFSESVQFVSTKSGYSFQKERPVLFLKQKEQLLENEILFELLGNVFY
                     GELEDMTELIDRFHLSEATFRRYLKQIQPVLEEYGLELSLYPLDLKGEEANIRKFFKD
                     FYYEGEMTPHTLVPPRDLHELVQATFYDKFEYFSIGTGTSPAEFYYSLYIAIERVRQG
                     KTIAIPQGLIERVIASENFRLMYSLKEAIQTNYQVALSEEEFCWLY"
BASE COUNT         3357 a         1540 c         1931 g         3164 t
ORIGIN      
        1 gtcccttaat tttgatatag gtttcgtcca ttttccatga atagaaggat tgtctatttt
       61 tcttcttcca aagataatag aggactttgc tgtactcttg tacccaacga taaatcgtag
      121 tatgacaaac atttattcca cgatcatata acaattcctg aacttcacga tagcttagat
      181 tgtaacgcag gtagtaacca acagcgacaa taatgacgtc ttttttgaat tgtttgcctt
      241 taaaatgatt cattactctg tcctctctgt cttttttctc aattttacac taaaatagat
      301 tttttggaaa actttgcaac agaaccgcca atcatatgga agccaccgat taggtatttt
      361 atgggtttag tcggaaatgt ttcaagagca atttccatca tatcgataat gccatgatga
      421 ctacagccag taaagacaat cagaccgtct tcttgctcaa ttacgaccaa taattcatct
      481 gaaaaatcat cataaacaaa tttatcatcc atctttttgt ataaattctt ggtggtcgag
      541 tttgctttgc ctagggggat gatatggaag ctcggagcaa gttctgtttt cgtttttatt
      601 gtatgtaaat tctcatgcat tttaaggatt tcatttttag gaataccaac atacagaaac
      661 gtggttaaaa tctttaaata atggggtaaa gttacacctt cagctgtata aataggggcg
      721 tttcctgatt ttaaatatct taacccgccg gtgtggtcag aatgaccgtg tgaaataatc
      781 actgcctcca gatcattcaa agtttccccc attttagtcg cattatagac taatttttta
      841 ttagcgccag catcgaagag atatttcttc cctgagtagt taattaagag agataaccca
      901 tgtccacttt taaagttcaa atttattctt gagttttcaa ataaaacctt gatttccact
      961 ataacatctc ctttcacatg aacgtgtatt catatattgt agcacattaa gttctatttt
     1021 ttgttgtaat taccgaaaaa aatattaatg gacgcttttt acgctttatt tcgtatgtgg
     1081 aagaaaattt cttaggatgt ggcgggggat tggggcaaag ctaaattcca attacagtga
     1141 tcatttaatt agacaccttt aaatacccac actttcatca acactataat ttagggaaag
     1201 aaaagtgttg gcatgatata gaaaaacctt taattaacag cgtttcctaa aattggcacg
     1261 catcttgctt atagaaaagc gtaaggatag gaggaatgaa aatggcaact ataattcttg
     1321 ccagccatgg ggaatttgct caaggattaa agcaaacagc tacaatgatt attggagata
     1381 gtgtaccaat tcatgccttg tcagcattta gagatgaaga tgaatctatt ttggtacaaa
     1441 taaaaaaact tttagccaca atagatatag aagaaaccta cattttaact gatattctag
     1501 gtggtagtgt gaataatgat atgctcacta ttattaaaga gtatgaggga ttgcaattaa
     1561 ttactggaat gaacttacct ttagttattt ctattgcaac ctataatgga aaaattgggg
     1621 aaagtgagct agaaaagctt attaaagaga gtcaacaatc agtgattgat tgtagaaaat
     1681 tattagtaga acaacttact ggaggagatg acctatgatt aagttagtac gtattgacca
     1741 tcgtttgttg cacggacagg tagtattttc ttggagtaaa tcattaaata tcaatcgtat
     1801 tattattgcc aataaagagg cagcgaatga tgaattcaaa aaaatgtctt tgaatttatc
     1861 taaaccgact ggcattaaat taacaatttt ttcagttgaa cagttactag aaaaaatgcc
     1921 taaaatcgaa acacttaacg aaaatatcat gcttattttt ggtaatacaa aagaaattcg
     1981 tcaattttgt gaagcctatc ctaaagtaca agaaatcaac tatggaggga taatcaaaaa
     2041 agaaggttcc aagcaattta gtaatgccat tttcttgaat gaatctgagc aagaagatgc
     2101 caaaaaatta aaagctcttg gcattaaaca atttattcaa caggtaccaa cttctaaaaa
     2161 agaagatttg aatacaatgt tataaaggag gaatgaaaat gctcgttcag tcaattggtt
     2221 tagggttaat cggtgttttt tgtattttag actcaaggct tttaggaaga atgaattttg
     2281 aacgaccgtt gattgtcagt acgcttgttg gtttggtact tggagacatg gaaaaaggat
     2341 taattgttgg agcctctttg gaattgatgt ccttaggatt agtaaatatc ggagctgctg
     2401 caccacctga tatgaatatg gcatcaatta ttgctacagc ctttgccatt ttatcaaatg
     2461 cgaatgcaga agcagcatta acgattgcca ttccaatttc agtgttaggt caaatactag
     2521 gtatcttaat gcggacgatt ttgtcaaatt tgactcacgt tgcggatcgc tttatcgaac
     2581 aagggaaatt tagccaagca aggagaattc atatacttta tggctcggga ttatatgctc
     2641 tcatgtattt tattcctatt tttctagcaa tttattttgg aacgaatctt gtttctcaga
     2701 ttgttgatgc gattcctgag tggctaacaa atggcttaac ggttgcaagt aaaattttac
     2761 cagcatatgg gtttgcgttg ttattacaaa cgatgttaac gaaaaaaatg gtgccatttt
     2821 tattacttgg atttttaatt actgcttatt ctggattggg aatcattggt attgcagcct
     2881 tcgcatgtat tgttgcgttt gtcatggttc aagttcaagg taaaaactca aatggtaacc
     2941 aaaatgagcc agatccatta gatgacttat aaggaggtag attaagtgaa agagaaagat
     3001 caaaatgcat ggaaatatcg gcagttctta tggcgttcat gggcaattca agcctcatgg
     3061 aactatgaac gacaaatgaa catgggtttt atgtacggaa ttgcaccaat tctagataac
     3121 atttacaaga atccagaaga tgaagcaatg aagaaagaag cttacgagcg gcatatgatg
     3181 tactacaact gtacccctca aacaagtgca tttgtgttag ggttaactgc ttctatggag
     3241 gagcaatact acgaagacca agaaaacttt aatccggaat caatcagtgc agtgaagact
     3301 tctctgatgg gaccgctatc tggtgttggt gattctttct ttcaaggaac gattcgggta
     3361 ttagcctttg gactaggaat taatttagcc caacaaggta gtattttagg tccaattcta
     3421 gcaatgttaa tttcctttgt accttccttt ttagttactt actatggtgg gaaaattggc
     3481 tataacatgg ggaataaata cttgtctaaa ctgtatcaag aaggtttgat ggataaagta
     3541 atgtatgttt gctccattgt ggggttgatg gtcattggtt cgatgattgc cagcatgatc
     3601 gggattacaa caccaattca aatgggtaaa gcttttgtct tacaagatgt attagatagt
     3661 attatgccac aatttttacc attaggatta accttcttca tgtactggtt attgcagaaa
     3721 aaggtcaaaa caggatggat gttggcaatc tgtttagtcg gaggaattat ttttagtttg
     3781 ttaggtatct tacaataagg gaataaccaa taaatttggt tgaataatat aaataaggag
     3841 gaattcaatt gatgaattca aaagaaattg ttaaagaaat cgtagcgaaa aaagaggtaa
     3901 aatcaatcgt atttgttggc tgtggcgctt caaaagcgga cctttatcct gcaaagtatt
     3961 ttctagacca aaatgcgaag cagttacgga ttagtcatta cacagccagc gaatttaact
     4021 atgcaacacc agcatctgta gatgagtcaa ctgtcgttat ttcagcttct ttaggaggta
     4081 cgactccaga aacagttgaa gctaacgcag tagctaaaga aaaaggtgct acagttatta
     4141 gtctaacacg aagcattgac tcaccgttaa caaaagatgc agattatgta atttatcatc
     4201 gatttgcaga gaactatgct gctaaattag aaaaaacagg ctactgttta gaattggcag
     4261 tagaactttt acatcaagta gaaggttatg accattatga agcaatgcaa gaaggatttg
     4321 ctactatcta tgatcttgcc caaaaaagtg cagaatcagc tcgtaaagat gcgaagaaat
     4381 ttgctgaacg ctttaaagat gaaaaagtta tttatgtaat gagtagtggt gctacacatg
     4441 aagtagcata ctcaacatca atttgcttga tgatggaaat gcaatggatt aattctggta
     4501 ccttccattc aggagaattt ttccacggac cattcgaaat tgtggataaa gacgtaccgt
     4561 ttatattatt aatgaatgat ggaaaaacta gaaatataga tgctcgagca ttaactttcc
     4621 ttgaacgctt tgatacgaaa acagaagttg tagatgcctt ggattatggc ttgtcttcac
     4681 atattgctaa agaagtctta gactacttta acccattcgt gattactgca gtatttagag
     4741 tttatgcaga agaattgtca gaagcaagag aacatccatt aactaagaga cgttatatgt
     4801 ggaaactaac ttattaaaaa atagatcaaa ctaaataagg tggcttgaga aattaagcca
     4861 ccttgttttc ttcaatgtga ttttatacat atggtaaaat aactagtaca tattgtgaaa
     4921 gcaggtggca agatgcagcg attaaatgac tatctttatc aactaacatt gcttttgaaa
     4981 tctacgcctt cagataatta ttcagctcgc agtatttcgc aagctttaca gttgaataga
     5041 agtacaatca gtagctactt aaatgaaggt gttcgtgaag ggcttttcat aaaagtaaaa
     5101 agttacccgg ttttattttt acatagaaca gctcttgaag aactacatat cacactgaat
     5161 aactccgaaa tagaatcaat tgaaagcttg ttaacaattt ctcaaaaacc cgcattagat
     5221 caagtaattg gctctaaagg aagtttgaaa gaagcaattg atcaaattaa aacggcagtc
     5281 ttatatcctg gaaaagggtt gcctttatta ttgatcggcg ctagtggatc agggaaaacc
     5341 tttctagcga ataaaatata tgaatatgca gtagaagaaa aggtcattca cacatcggca
     5401 cctttcatag attataattg tgcacaatat gtgagcaatc cagagttact atcctctgct
     5461 ttatttggct acacgaaagg agcatttacc ggagcaagcc aggagcatac tggtttgcta
     5521 gaaaaagccg atggaggagt attgttttta gatgaagtgc atcgcttatc tgaagaaggg
     5581 caagagaaat tatttacatt tatggatacg ggtgaattct ctcctatggg ggataatagt
     5641 attcggaaaa aagccgatgt tcgattagtc tttgcaacaa cagaaaatat atatacgact
     5701 ttcttaccaa cttttcttag gagattgcca gttattgtta atctacctag atttcaacaa
     5761 cgtccgtcgt ttgaacgtct gtcattgatt gatgaatttt ttgtttctga gagtaaaatt
     5821 ttagctaagg aactatctgt ttctgatgca ttgattcatt tcttaatgaa tagtgatttt
     5881 gaaggtaacg tggggaatat taaaaatatt atcaagtatg cttgcggaaa cgcatatatc
     5941 caccagaaga gtcagcaaac aattcaagtt aaattattgg atatgccttt agagtacagt
     6001 tataaattca aggagcaact aaataaaccc agaaagaaaa gagcagatcg aatctactat
     6061 ccagaagaaa cacgacaagt gcaactagaa agaaacaatc agctttttgt tcaatttttt
     6121 gaccaattac ttactggatt ctctgaagtg attgaaaata acaaggatat taaactattt
     6181 ttagaagaaa tggttaccaa ggtaacacaa gtaatggata cgcttatttt tcaagaggat
     6241 tacgaaaaag agcagtcttt atacgccatt ctaaactatc atattcgtca aagtattgat
     6301 tttatgcgag aaagctacgg gtttgaacaa gatggtaacc gggtagtcgc tttggccaac
     6361 tatctatatg tcaaggataa tcaagtgatt tttgaaaata gtcttcaaga aaagaaaacc
     6421 aaagatcagc ttaacgaatt ttttgctaat gttcttgaaa ccccttattg gtatgcaaaa
     6481 aaaatcttaa gccttttatc tgagtgttta gatcaacctg tgtatgaaga ggacattttc
     6541 tttattacgc tatattttta tagtttgaat gtcacgaatg ttaaaacagg tattaagagt
     6601 attgtgctag ctcatggtta ttctacagct agtagtatgg cgaatgttgc caaccgtatg
     6661 ctgaataaga acgtttttca agcttatgat atgcctttag atattacatt agagaaaatt
     6721 gaagcaaaat tgattcaatt ccttggagat tatcgaacag attcaggctt gattttattg
     6781 gtagatatgg gttcactaaa ccaactaggc ggtttattag tgaatcatct aaatggacca
     6841 ctgttaatca ttgatcatat caatacaccg ttattattgg aagtcggcca acaagtatta
     6901 aacaataaaa gtatcaccga aataggagca gaaattgaaa caagtcttac tttcaaaaag
     6961 cagttactac ttcccaagaa aaagaaaaag aaagccatca ttacttgttg ttatacaggg
     7021 attggtagtg cgacccagat tcaggagatt ttaacgaaat gcttgaaaga tgcagttaga
     7081 gaattagtaa ttattccgta tgattacaaa aagctgttag aaaacaagaa ttttgagact
     7141 ccttttcaat tatacgatgt catcatgatt gtaggtacag aagatcccaa aattaatcag
     7201 attccatata ttggattaga tcgcctgatt aatggggaag caattggcga atttgttcat
     7261 tacttggaaa aagagctgac tattgaagtg aacgatttac aaaaagaatt aattttcaat
     7321 ttttcaatta gtaaaattgt cgaaaattta accattttgg atccagataa ggtgctatct
     7381 tttgtacaaa aagcaattaa agaattatcg aagttattaa attttgattt ttctaataat
     7441 cagctgtttt tgttgtacct tcactgtagt tgtatgattg aacgaattgt acgtaaagaa
     7501 agtgtggatg agcaagagga cattgaagaa tatatgcaag caaatggaga aataatggat
     7561 aaaattcata gcgctttttt tgagattgaa agggaataca caattgaaat accagattta
     7621 gagttgcgat tattgagcga tattgttcaa ggataggagt gaattcgaat gacaatggga
     7681 gtaatttttg atatggatgg ggtactcata gacagcgaga cattttattt tgagagaaga
     7741 atgaacttct ttcaagaact ggagatagat ccaggatcaa accagattga tgattatgtg
     7801 gggaaaacag aagctgcaat atgggaaaca ttagttcctg aggacaaatc attaagagag
     7861 gaactttatc cgaaatatgt agattatcga aaaacgcatc caattgattt cgctaaagat
     7921 ttacgaaaag aagtgaaacc gttacttgac ttcctcaaga agcgggatat accattggca
     7981 ctggcatctt cttctccagt tgttgagata gagagtatgc tcattcaatg tgaacttact
     8041 gaatattttt cctttgttat aagtggtgag tcattaaaac aaagcaaacc acatcccgaa
     8101 atatatttaa aagcgaaaca gcaattagac tgtgacttct ttattgcagt agaggattca
     8161 acgattggta ttaaatcagc aaaggcagca aatatctata cggtggcact aaaacaacca
     8221 atgcaaatcg atcagagtga agcagacata caaattgaaa gtctacaaga actggaacaa
     8281 attgttttag aaaaaggtta gtgaattaat ggaaataagg ctatatatct gtgctagcta
     8341 ttttgactaa ccaaaaaaac ttgctataat tcaggtgtag taaaaggtgc tggtaacacc
     8401 ttttacgaaa atgcttcggc agtgataatg ggattggctt tttaagtttt ttattttgtt
     8461 cgcaatccct aaggtcatgt gaatgatcct agggattgct agaatatttt gcaacattct
     8521 atctatttca gaacgtaacc ttccccagtt cattgggatt cattagcata caaccaacat
     8581 ttcaaaaaga aattgcacta caccattatt agctattttg actaacccca aaaaacttgc
     8641 tataattcag gtgtaggtaa aaggtgctgg tatcaccttt tacgaaactg cttcggcagt
     8701 ggtaatgagt gtggcttaaa ggactagtcc tttaagcttt ttactttgtt cgcaatctct
     8761 aagatcaagt taatgatcga taagattgct agaatatttt gcaacattct atttcagaac
     8821 gtaacctttc ccattccact gtgattcatt ggcaaccctc ctcacaacca acgtttcaaa
     8881 agaaattgta aagttgttgg ggtaccacga ccgaacaata ctacacctga atgatagtaa
     8941 gttgtctcat taagtatagc atatcctctt tttgggtaaa tagaaatcgg ttacattttt
     9001 tatccaagac caagtttttt catttggtct tatttgctat acccaaacaa ttccgcagta
     9061 tagtcgacgg tattgatttt atcaggtgag taatagaaac ttgttttcct tccccaaaac
     9121 attacctata aaggagaaaa aatggtatcg taattatata ggtataggat gaaatttttt
     9181 tctaagagga gggttgttga tgaaaaattt acagttaaaa tttattgttg atccatcgat
     9241 tgtacgctgg tttcggatta tcaatcaatt tgagcgcaat caacttgcca caaaaggaga
     9301 attagcaaag agtaatcatg tatctgaacg aaccattcaa acagatgtca ataaaatgaa
     9361 ggactacttt tctgaaagtg ttcaatttgt ttcaacgaaa agtgggtatt cttttcagaa
     9421 ggaaagaccg gttctttttc tcaagcagaa ggagcaacta ctggagaacg aaattttatt
     9481 tgagttgtta gggaatgtct tttatggcga attggaagat atgacggagc taattgatcg
     9541 ttttcattta tctgaagcga cttttcgtcg gtatttgaag cagattcaac cagttttgga
     9601 agaatacggc ttagaattga gtctttatcc tcttgattta aaaggagaag aggcaaatat
     9661 tcgcaagttt tttaaagact tctattatga aggggagatg acgccccata ctcttgttcc
     9721 accaagggat cttcatgaac ttgtgcaagc tacattctat gataaatttg agtatttctc
     9781 gattggaaca gggacttctc ctgctgaatt ttattatagt ttgtatattg cgattgagcg
     9841 tgtgagacaa ggaaaaacga tagccattcc tcaaggtctg attgagcgag taattgctag
     9901 tgagaatttt cgcttaatgt attccttgaa agaagcgatt caaacaaatt atcaagttgc
     9961 tttatcagaa gaggagtttt gttggttgta tt
//
LOCUS       DAFENC010000070         9888 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.074, whole genome shotgun sequence.
ACCESSION   DAFENC010000070
VERSION     DAFENC010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9888
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.074"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(109..2229)
                     /locus_tag="LP493_002574"
     CDS             complement(109..2229)
                     /locus_tag="LP493_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBL2134683.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2459..3637
                     /locus_tag="LP493_002575"
     CDS             2459..3637
                     /locus_tag="LP493_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HBL2134684.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3653..4411
                     /gene="aroD"
                     /locus_tag="LP493_002576"
     CDS             3653..4411
                     /gene="aroD"
                     /locus_tag="LP493_002576"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBL2134685.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4434..4919
                     /gene="ybaK"
                     /locus_tag="LP493_002577"
     CDS             4434..4919
                     /gene="ybaK"
                     /locus_tag="LP493_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HBL2134686.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4990..6243)
                     /locus_tag="LP493_002578"
     CDS             complement(4990..6243)
                     /locus_tag="LP493_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBL2134687.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6360..7709
                     /gene="gdhA"
                     /locus_tag="LP493_002579"
     CDS             6360..7709
                     /gene="gdhA"
                     /locus_tag="LP493_002579"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HBL2134688.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7821..9167
                     /locus_tag="LP493_002580"
     CDS             7821..9167
                     /locus_tag="LP493_002580"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HBL2134689.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9475..9861)
                     /locus_tag="LP493_002581"
     CDS             complement(9475..9861)
                     /locus_tag="LP493_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBL2134690.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         3149 a         1800 c         2025 g         2914 t
ORIGIN      
        1 ctgagccaga atgaggttca ttctgaccca gatttgattt tgtacaaccc atcagtcctt
       61 attgacaaag agcctaattt tgtcgctgct ccttttaaat ttattttatc attcggaaga
      121 acttgtggtc gttccgtgaa gttcttggta cgtttgcgtt ttataaagat caacagttga
      181 ttgtccgttg tgttcactaa agacactagt tgacttgtca ccaagagatt tttcagcttc
      241 ttttaatttc tctaagccat tcttgtagtc ataatcactg gtatcaattg ggtctaatcc
      301 actattcgta tagaaccgaa gaagatcacc attattgatt tggtcagaaa cagctaactg
      361 tttatcaact ttttctttca gtgaatcaat ttcattctgt acttcctcag taggttcagt
      421 aatagcttca ccagtttcgt tactatagat cgtaccaccg tagtaagtat attttggtgt
      481 aacaaaatca ccatcacgga aagaaacaag ctgttcatga tctttcgaga atagatcttg
      541 tcctaactga atataatttt ttgtatctac acctagtaag tgaagtaatg taggcaaggc
      601 atcaacttgt ccgccgtaag tgtgattgat tccgccctgt gtttgtccag ggatatggat
      661 catataaggg acacgctgca tttgtgcatt gtcgtagttt gtccaagtag aacttgtttt
      721 tccaactaat tcagctagat ttttatttct tgaattcgag acaccgtaat ggtcaccgta
      781 aaggacgatg actgaattat catacaagcc gctttctttc aaataattga agaattcttg
      841 tacggcggta tctaaataat tggctgtcgc aaagtaaccg ttgatcgttt catcatttgt
      901 attggctaac gggaatcctg cttcgtcatt ggtgaatttt gaataaggat aatggttaga
      961 tacagcaatg aattttgaat aaaatggttg ttgcagacgt tccaagtatt gtacggattg
     1021 ttggaaaaat ggtttatcat gcaacccgta ttggaacgaa ttgtcatcat taacatcata
     1081 ataagaagaa tcaaagaaat aatcatatcc taaattcttg tatgtctcgt ttcgattcca
     1141 gaatgtacca gcgttcccat ggaataccgc actagtgtaa ccttgtgttt gacttaaaat
     1201 atcaggtgca gcttggaaag tattttttcc gcctaattgt gtgaacaagg agccttgatt
     1261 caagccaaac aatgaatttt ccatcagcgt ttccgcatcg cttgtttttc ctgcttttac
     1321 ttgatggaaa aagttgtcaa aactgaacgt gctgttgctg tggtaaagac tattgatgaa
     1381 aggtgtaact tcatgctgga gaccattctc atctgtcaat ttataatcga tcaggaattg
     1441 ctggaagctt tctaaatgga tataaatcac attttttcct ctagcgagcc cgaacaaatc
     1501 gtcatttggt gctgcataat gttcttttac ataattttct acttctttca tatcattggg
     1561 acttgcttct gcccgcactt ggtttgtctg gtaagtttga acaccgtcat aaaccatgaa
     1621 agcattcaag ccaagatatt tgaccaaata atcacgagag aatgttcgag tcagcaattc
     1681 tggacgatca gcttccgcca taaaaagatt tcctgagaaa atcataactg ctaatgtaga
     1741 gatcgcaaaa gccattcttg ctcggatcgg gcgagggtcc aacttgattt tttttgcaat
     1801 cagcagaaca gtcaagataa taaaatcgat ccaatagatc acatcatatg ggcgaaacag
     1861 tcgaatggca ctttctccca gaccactcgc tactttccca gcacctaaaa tcgtgttgat
     1921 cgtaatgaag tccgtgaatt ctcgataata agtgacattc gaaaaaacaa gcaatgtcaa
     1981 aagaaaataa atgaccatca tcgtgatata agcaactcta gggcgtctga tataaagagc
     2041 aattccaagt aataacaatg tagttgcaat agggttgata aacaagataa agtattgaat
     2101 gccactttcg attccgagat ggaaatcaac taaataggca aaaatcgttt tcaaccaaag
     2161 taaaacgact agtaaagaaa aaaatccgag cctcttattc aaaaaggcag gtgtttttat
     2221 acatttcaag ataatcttcc tttctgcact tcttaatcac agaagtgtcc tgaaaccatg
     2281 ttacacagct cacttattct catttatttt actagtatga caatatagtg tcaattgaaa
     2341 ccagaagttt atgctgtttc attaaggttt tctttaagct tcatgaaaaa atgagcagta
     2401 agacaagtcc tatgtttttt gttatacttg ggaagagaaa gctaaagcag gtgaaggaat
     2461 gaaagtaaaa gtaaaaaaaa gagcaagcaa tcgattgaaa aaaggatatc cactgatcca
     2521 aaaagaagac cttgctcatc cccaaaaaga aaccacgcaa tgggtggaat tagttgattc
     2581 gcaaaaccaa tttatcgcaa aaggatatct aggaaagcag aataagggaa tcggttgggt
     2641 attgagccag cagaacatcc catttgatca atcttttttt gaagaatttt ttgtgaagtc
     2701 aaaagaaaaa agaactttct ttttttcaga tgattctact accgcttttc gtatattcaa
     2761 tggagaagga gacgggatcg gcggtctgat tgttgattat tatgcaggtt atgctgtttt
     2821 ttcttggtat aacgaaacgt tatatgcaca tcgtgaatta ttgattcaag cttttcgtga
     2881 aatctacccg gaaatcatag gaggctatga gaaaattcga tttgaatcag taaatctgcc
     2941 tgagagccag ttcatttacg gaaaagaggc accggaaccc ttgatcgtaa aagaaaacgg
     3001 agtaaaattt gccgtttatt taaatgaagg attaatgact gggatctttt tagaccaaaa
     3061 agaagtacgg ggatcattag cagaaggttt cgcttctggg aaaacagttt tgaacatgtt
     3121 tagttatacc ggcgcctttt ctgttgctgc cgcaatggga ggggcaatcg aaacaacaag
     3181 tgtcgatcta gcaaaacgca gtttaaaaaa aacacaggaa cagtttgaag tgaatggttt
     3241 ggatgtcgat cagcaaaaaa tcattgttat ggacgtattc gagtatttca aatacgccaa
     3301 aagaaaacaa tttttatatg acatgattgt attggatcca ccaagttttg ccagaaataa
     3361 gaaaaaagtc tttcgcgtag caaaagatta tggggaactg gtcaaggata gtctggatat
     3421 tttagcagaa gacgggatac ttattgcgtc tacaaatgct gcgaatgtct cgatagaaca
     3481 attccaaaca atgattgaag aggaattcca tgccaaaaat gtttcttttg aacaacttgc
     3541 tttatatcgt ctgccaaaag atttccagac gacggatacc tttttagaag gcaattatct
     3601 gaaagtgttt gtttatcaaa ttaaaaataa ccattagaag gagcgatgca gaatggttcg
     3661 ggtaaaggga ttgaatatag gaagcggtag accaaagatt tgtgcgcctc ttatcggggc
     3721 cgtccgagag gaagtattac gtgaagcagt tcttgcacgt gaagcagggg ccgatttagt
     3781 cgaatggcga gtcgatcatt atcgtgaagt tttttctttt gatgaagtag cagaaacatt
     3841 ggttcttatc catgagatgc ttgatggact gccgttatta tttacgtttc gtaccttagc
     3901 tgaaggcgga gaacaagaca tatcgatccg tcagtatcgc gacctttatg aacatgtgat
     3961 acacacagga ttagtagata tggtcgatat cgagttgttc aaagtagaaa gtctaggaaa
     4021 aagactgata gaggaaatca agtctttaaa cattccttta attatcagta gtcatgattt
     4081 taaagaaaca ccagcagacc ctgtcttgct ttaccgattg aatgttatgg aacattttgg
     4141 agccgatatc ggaaaactgg cagtaactcc caataatgaa cgagatgttt tgcggttgat
     4201 ggagttgact agacgggcaa atgcttttgt ctccatgcct attattacga tgtccatggg
     4261 aaatcttggt aaaatttctc gtctggttgg cggaacgacg ggttccgtta tgacatttgg
     4321 ttccttaagc agcgattcta cttctgctcc aggacaatta ccggtcaaag cattgaagca
     4381 aattattcaa ttattaaatg aaccgttgta gaacaagttt gaggtgatat tttttggcaa
     4441 agaaaaaaat agtaaaaacg aatgcaatcc gtatggtcga acaaaaaaag attccctata
     4501 cagagcacga atatgagtgg gacgaaagcc acctaagtgc gtcatcggtc gctgaacagc
     4561 ttccagaaag ccaatctcgt atatttaaaa cactggttgc tgtgggcaat gtgacggggc
     4621 ctcttgttgc tgtgataccg ggagaagccg aattgaatct aaaaaaatta gcaaaagttt
     4681 cagggaataa aaaagtagaa atgctccatt taaaagattt ggaagcaacg accggataca
     4741 tacgtggtgg ctgctcgcct ataggtatga aaaaactatt tcctacttat ttagatcaaa
     4801 ttgcagaaag ctatgaacaa atcattgtct cggctggcag aagagggcta cagatggagt
     4861 tagcacctca agatatctgt gcattaacga gcggacaatt tgcagatata aaacaataaa
     4921 tcatacgtat aaaagaaaga aggaggccgg gatgttgttt gtccagtctc cttctttctt
     4981 ttttatacat tatgctcttt gcccggcatt cattcctgct acatgccctg tagcgaaagc
     5041 cgctgtgata ttaaagccgc cagtataacc attgacatcc agtaattctc ccgcaaaata
     5101 cagaccatca atgattttac tctccaatgt tttaggataa atttccttta gagaaacccc
     5161 tccgccagtt acaaatgatt tctcaatagg aaaagttttg ttgattgata gcttaaactc
     5221 tttgcatagt tgaacaaaat cttgaatttg tttttgagag gcttgttgtc ctgtcagatg
     5281 atccatttca agccgctcaa gaaagaaaac taacaatcgc tcaggcaata taccatgcca
     5341 agcattgacc aagttctttt tggttgcttt acttttttct gtcaatatat gaataagctc
     5401 ttgtttggtt tgtgtaggga aacaatccag agaaagtgtc actggttctc ccgttttctc
     5461 taattcttta ttgacaaaac ttgaacaacg cagtgcagcc ggaccagaaa taccgaaatg
     5521 ggtgaaaagt aaatccatcg tatgttcagt caatacacga ccttttttat ttaaaacgcg
     5581 taaagtgatg tcttgtaaag aaagcccttg aagtgttttc tcctgaatat acggttcatc
     5641 cgatatcaag ggggactctg tcgcataaag aggcgtcacc gtgtgaccca ctcgcttcac
     5701 gatcttgtac ccatctccag tagaaccagt agatggataa gtccgtccac cagttgttaa
     5761 gataatggca ggagcatgga actcttcgaa ttccgtgcgt ataccgtaaa ttttatgttc
     5821 tttgtggatc aatttctcta ctcgagtaga gaatagaagc gtcacatcta gttctttcag
     5881 acgattgagc aatgcttcga taatcgtttt tgatttattt gttacaggaa acatccgtcc
     5941 atgatcctct tcttttaaat gtacgccttg tgattcaaag aagttcatga tatcgaaatt
     6001 attccattgc gcaaacgtac tatataaaaa ctttccattt ccaggaatat gtgcaatcaa
     6061 atcatcaaca ggacgattgt tcgtaacatt gcaccgacca ccacctgtca tcagtagttt
     6121 ttttcctgct tttttgtttt tttcgatcaa gagtacgcgt gcgccttgtt cagctgcact
     6181 gatcgctgcc atcatcccgc ttgttccagc gccgactacg atcacatcat acagtttttc
     6241 cattccctca cctcaaggaa agtgtagcat atctgaagaa agaaaacaga aaaaaatgtt
     6301 ttgagccaaa agagaaaatg agctaaaatg agggaagata agcaaaggag cgtggaacga
     6361 tgacaaacgc aacagaatat gttcaagcaa ttcaagaaaa gctacatcaa aaggatcaag
     6421 ggcaagaaga atttttacaa gcaatcgatg aattcatgcc cacggttatg tcttttttgg
     6481 acactcatcc cgaatatatc gaaaagaata tcttagaact tttaacggaa ccagaaagag
     6541 ttattcaatt tcgagtgcct tggcaagatg atgaaggaaa ctggcgagta aatagagggt
     6601 accgtatcca atacaactca gctatcggcc cttataaagg tggattgcgc ttccatccta
     6661 gtgtcaatct aagtatcttg aaatttttgg cttttgaaca gattttcaag aatagtttaa
     6721 ccggtctgcc aatcggtgga ggaaaaggcg gaagtgactt cgatcctaaa ggaaaatctg
     6781 ataatgagat catgcgtttt tgtcaaagtt tcatgctgga attgtcaaaa catatcggcc
     6841 catcgattga tgttcctgcg ggagatatcg gtgtaggagc tagagaaatc ggctatttgt
     6901 tcggcgaata taaacgattg aaaaaatatg atactggtgt gttgacaggt aaacctttgg
     6961 atttttgggg aagtaagata cgtacggaag ctactggtta tggattagtg tattatgtca
     7021 aacatctatt gaacgaagaa aaagattcat ttaatcaaaa aacagttttt gtttccggaa
     7081 gcgggaatgt agccatttat gcaatcgaaa aagtgcaaga gctaggcggg aaagttgtta
     7141 catgttcaga ttctagcggg tacatctatg atccagaagg aatagatgtg aaactattga
     7201 aagaagtcaa agaaatcaat agacaacgtt tgacggaata cgcaaaccaa cgtccttctg
     7261 ctatttatca tgctggagaa tctgtttgga cattgaaaga aaaagcggat atcgctttgc
     7321 catgtgctac tcaaaatgaa atagacgaaa gcttggccga aatcttagta gaaaatggga
     7381 tcaaaatcgt agcagaaggc gctaatatgc catgtacagt aaaagctgtt tctgttcttc
     7441 atgaagcagg cgtgtggtat tgtccaggaa aagctgctaa tgctggagga gtagcagtat
     7501 ctgctttaga aatgagtcag aacgtccagc gattgacttg ggaaagagag caagtggatg
     7561 agcagctgga tcaaatcatg gaaacgattt accatacgtg tcgccaaaca gcagccgagt
     7621 acggcgacga aaaaaatctg cttcttggag caaatgttgc tggatttgaa aaagttgcca
     7681 aagcaatggc agcagaaggt ttagtttgaa aaatgaaact ttcttggaaa tattgtcagc
     7741 attttgttta tttgcttgaa aaataataaa aaaaaacgta aagtattacc tgtagagtaa
     7801 acctataagg aggagaacaa atggcacaca ttcattttga ctattcaaaa gtagcaccgt
     7861 ttgtcaacga acaagagtta gggtacatgc aaagccaagt aacagcagcc cacaacgaat
     7921 tacgggaagg tactggcgca ggaagcgact tccgcggctg gatcgattta ccaacgaact
     7981 atgacaaaga agaatttgca cgtatcaaag aagcagctaa aaaaatccaa tctgattctg
     8041 aagtattagt tgttatcggt atcggtggtt cttatttagg cgctcgtgca gcgatcgact
     8101 tcttgaatca cacattcttc aatttattag atagcaacac aagaaaagca ccacaaatct
     8161 tctttgccgg aaattcaatc agctcaacat atattgctga cttgatcgaa gtaatcggtg
     8221 atcgcgactt ttcagtaaac gttatttcaa aatctggaac aactactgaa ccagcgattg
     8281 cgttccgtgt attcaaagag cttcttgtta agaaatatgg acaagaagaa gcaaacaaac
     8341 gtatctacgc tacaacagat aaagcaaaag gtgcagttaa agtagaagca gatgcagaag
     8401 gttgggaaac tttcgtgatt cctgatgaca tcggcggacg tttctctgta ttaactgctg
     8461 ttggtttgtt accaatcgct gttagtggtg cagatatcga tgcattgatg caaggtgccg
     8521 ctgatgcaag caaagcatac tcaagcgaca aactagaaga aaacgaagct taccaatacg
     8581 cagcaatgcg caacattctt taccgtaaag gcaaagtaac tgagttgttg atcaactatg
     8641 aaccaggaat gcaatacttc tcagaatggt ggaaacaatt gtatggtgaa tctgaaggaa
     8701 aagaccaaaa aggcatctat ccttcaagcg caaacttctc aactgatttg cactctttag
     8761 gacaattcat ccaagaagga cgtcgcaata tttttgaaac agttgtgaag gttgaaaaac
     8821 ctcgtaaatc aatcacaatt cctgaacaag cagaagattt agacggtcta ggctacttgc
     8881 aaggaaaaga agtggacttc gtaaatacaa aagcatttga aggaacattg cttgctcata
     8941 cagacggtga cgtgcctaac ttgctagtca aaattccaga aatggatgct tatacattgg
     9001 gttatacaat gtacttcttt gaaattgctg taggtatttc aggttacttg aatggaatca
     9061 acccattcga ccaaccaggt gtagaagctt acaagaaaaa catgttcgca cttctaggca
     9121 aaccaggctt tgaagatctt gctaaagaat tgaacgaacg cctgtaagat aagggttttt
     9181 cgctagattt aaataatcag tgatagaaac atgttcgctt taaaatgaaa actggtaccc
     9241 atttaggtac tcaaacatac tgcatcgttt attcagaata aggggctgtg acaagacgtt
     9301 tgtcacagtc ccttgtttgt atagaaatcg attgattgcc ttgctcttta gtttgtttta
     9361 ggactttaag aacagtgagg ctgacttcga aggttaattc tgtttttttg ttttctagaa
     9421 tcagtaagca aaaaagcact cacttcgagt gcttttttgc gatatattct tagcttaaga
     9481 taggcctaat ttttctttta cagatgaggg taccttatcg ctggtaatta cttttttctc
     9541 tatgatccgc ttttcgcttg ctttcaactg caagatcgtt ccttcggggt aagcagaacc
     9601 attggcagag tcaccagaag taatgacatc gaaatctaac tgtctttttt caccgttttc
     9661 agcataagca tctacgttgt atttaaaacc tcttccaatt acttccccat tatctgcttt
     9721 gatatcagtt tctgcaggca ttggagcttt gactaccgca taataatctt tacctacata
     9781 agtagactga tagtagtccc aacctttcca tcctataaaa gcaatcaata tgataacgat
     9841 caaccctaaa atttttttca tgaaagatct ccttttttat ttttatta
//
LOCUS       DAFENC010000071         9485 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.075, whole genome shotgun sequence.
ACCESSION   DAFENC010000071
VERSION     DAFENC010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9485
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.075"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..386)
                     /locus_tag="LP493_002582"
     CDS             complement(<1..386)
                     /locus_tag="LP493_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2134691.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATTCGLSRPYLNQIENGGV
                     TASTKTMRKIFDQLESFNPELPLTLLFDYVRIRFPTTDARKIIQEILHLKFDYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGV"
     gene            complement(642..896)
                     /locus_tag="LP493_002583"
     CDS             complement(642..896)
                     /locus_tag="LP493_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134692.1"
                     /translation="MIGKIQSDPELEEELYRLNFDIRKNGVKVPDDPYVIDEETDARM
                     ELNQVISELERIADFAKEPDIRQYLFEIKAELEIEGITAE"
     gene            complement(921..2063)
                     /locus_tag="LP493_002584"
     CDS             complement(921..2063)
                     /locus_tag="LP493_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HBL2134693.1"
                     /translation="MTFLDLFAGIGGFCLGMEQAGHQCIGFCEIDDFARQSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AAILQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQNRERI
                     FLIGHSRDACTEQVFPIIGSSPTSDQNIRNLLNINPSNRGMGGQVYGSDDVAPTLTGD
                     EGIKIALPVDDGISVAGMLLGNFEQGNRVYEITGTAPTLSTKQGGTKIMLRKNETEYQ
                     EVKPGNSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKEVKTDDL"
     gene            complement(2123..3475)
                     /locus_tag="LP493_002585"
     CDS             complement(2123..3475)
                     /locus_tag="LP493_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBL2134694.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVDKKFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREISDIGGLNVNTEG
                     "
     gene            complement(3546..3890)
                     /locus_tag="LP493_002586"
     CDS             complement(3546..3890)
                     /locus_tag="LP493_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HBL2134695.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDVEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            complement(3900..4274)
                     /locus_tag="LP493_002587"
     CDS             complement(3900..4274)
                     /locus_tag="LP493_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL2134696.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            complement(4287..4601)
                     /locus_tag="LP493_002588"
     CDS             complement(4287..4601)
                     /locus_tag="LP493_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBL2134697.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            complement(4715..7942)
                     /gene="fss3"
                     /locus_tag="LP493_002589"
     CDS             complement(4715..7942)
                     /gene="fss3"
                     /locus_tag="LP493_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HBL2134698.1"
                     /translation="MKKPRFKNWRLLATLSLLCQTIGGSLGPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSEKAKLVSVLWKEAGTDVDTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     ESKINQAIADYQKKPSFHNSTVKTVLGQSTTVTDTNGLNLSEFDEVVENIANIDYRVN
                     GNQLVITPNANSKESGELTLKKSANTGTPVAYKMAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKETGNVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGAKVTIT
                     EKSVPAPYTIDTTPITATIKSGETISVTSKNTREKGQIILNKMGVETGTDLWNDKYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASNGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGNETQGKAEFKGAEYTL
                     FTAKDGQAVKWSEAFKPELVKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDNEKNAVITRDVTAKEQVIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTSEITGAEDEAITAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKADYTKSEYIFTITEKGQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLGTWKDGGKELTDLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     EATKAAQEKDEKAKPVVIAETTATLANKEKTGTWKILHKLTAEQVLDKTIVLFNYVYE
                     NKKPYEAGDDPVAKDASLNNQAQTVNCTVERHVSIQTKAHLEDGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDNTTKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYGKDGNINGKHNEDLKEKTQTLTPKKVPTTPSAPEQPEIPTVP
                     SDSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            complement(8021..8683)
                     /locus_tag="LP493_002590"
     CDS             complement(8021..8683)
                     /locus_tag="LP493_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134699.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            9300..>9485
                     /locus_tag="LP493_002591"
     CDS             9300..>9485
                     /locus_tag="LP493_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134700.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTR"
BASE COUNT         2598 a         2100 c         1617 g         3170 t
ORIGIN      
        1 acgcctttat cttcttcatg tgacaacatc accacaatat ctcccataac atattgttct
       61 tgataggagt aaaaggcgta atcttcgtgg agcatataat caaatttcaa atggagaatc
      121 tcttgaatga ttttcctcgc atccgttgtg ggaaagcgaa tccttacata gtcaaacagt
      181 aacgttaaag gtaactcggg attgaaactt tccagttggt caaaaatttt cctcatggtt
      241 tttgtcgatg cggttacgcc accattttct atctgattta agtacgggcg actaagtcca
      301 caagtcgtag ctaatttatt ttgtgaaacg ccatattcat tacgccggtc ttttaatagc
      361 cgataatcta aattcctttg tgccaagttc tcacctccaa atttaaggtg ttaacttttt
      421 caaatcagtt aacatctaca caaattgctt attatccttg ataggacagc cattccttat
      481 cgttgcttgc ttattttttg tgtttttgta cccccctgtt agatacgggg ggtgagacat
      541 catggccggc taacgccgtc cataaacagg cacagcacca cggaggattt ctgcttcgca
      601 aatcccccgc ggtcagtgcc tatcagtggt ttatttggcc gttactccgc ggtaataccc
      661 tcaatttcca actctgcttt tatctcaaac aagtattggc ggatatcagg ttctttagca
      721 aagtccgcaa ttcgttccaa ttcactgatg acttgattca gctccattcg agcatccgtt
      781 tcctcatcaa ttacatacgg atcatcaggg actttcaccc cgtttttgcg aatatcaaaa
      841 ttgagccggt acagttcttc ttccaattcc ggatctgact gaatcttgcc aatcacccag
      901 tagattcccc aatcaactca tcataaatca tctgttttta cctcctttaa tcttctagca
      961 atatcaaaaa tgaccggaac tgttacagaa tttccagcct gcttatacaa ctgactatct
     1021 gaattgactt gagaagctcg atcaaaagcc cagtccggaa agccctgaag ccgccagcac
     1081 tccctaggtg ttaactttcg aatttgatac tgatccgtga cgactgcttg ttggtctcct
     1141 gttaataagg tatgcacact ttgttttccc agacggcctc gacgacttgt ggaattagga
     1201 aaagccaggt tcacactgtt ccctggcttc acctcttgat attctgtttc gtttttccga
     1261 agcatgatct tcgttccgcc ttgtttcgtt gacaaagtag gcgctgttcc agttatctca
     1321 taaacccgat tgccttgttc aaaatttccc agtaacatac ccgctacaga aattccatca
     1381 tctaccggca atgcgatttt gattccttca tcaccggtca aggtaggcgc tacgtcatct
     1441 gacccataga cttgtccccc cattcctcga ttggaagggt tgatatttaa taagtttctg
     1501 atgttttgat cagatgttgg agacgatcca atgataggaa atacttgttc ggtacatgcg
     1561 tctcgagaat gtccgataag gaagatccgc tcacggtttt ggggaacgta ggcctttgag
     1621 ttaagcactt gccattccac atcatacccc aatccatcca gcgttcggag gatcgtctcg
     1681 aacgtagccc ctccttcgtg attgagtaat ccccggacgt tctcaaggaa taaaaactta
     1741 ggttggagaa tagcggcgaa ccgagcgatt tcaaagaata aagtacctcg agtatcggaa
     1801 aatccttgcc gctttcccgc aattgaaaaa gcttggcacg gaaatccacc gcaaaggata
     1861 tccactggtc cgagagattg aataaactcg tctgatacac ttgtgatgtc atgcatttcc
     1921 acctccttac ttgtatcatg gattgcctta taactctggc gagcaaaatc atcaatttca
     1981 caaaagccga tacactggtg acccgcttgt tccataccta agcaaaagcc accaatccca
     2041 gcgaataaat ctaaaaatgt cataaatcac ctcgtaaaaa aagcccagga ttcttgacac
     2101 tcctaggcta catactatta ttttatcctt ccgtattaac gtttaatcca ccaatgtcgc
     2161 taatttccct taagaaatca tatccttttg gtacaagtgg cgtataaaac tcactaatca
     2221 cactccctcc cgtatctaca tagcctcgac ctttgatacg cttcataaag aattttttat
     2281 caacctcgcc aaacatcatg gaatatccca gttcactcat acgacccaaa gccacccgga
     2341 aattaaattg atcgcgaatc ccgtctccta aatatttcgc atccggtctt tgacaagcta
     2401 gaatcagaaa gaaaccagat tgacgaccta acatcacgat ttgtttgagc ttattcaaaa
     2461 tcaccgcact ttccttcgtc gttaacattt ccatataaac cacgtattca tcaaagatta
     2521 aaaagtttgg tggaagtcca agaaacgcat aattctctcc tgttttgtag ttgggcattt
     2581 ctttcattgc cttgctacga gtcatcatgc gctcatagaa atcttccaca caagcagaaa
     2641 tttcctcctt ttgggaatag acatgaggca ttaccgtacc taaatcggct aagtccgcat
     2701 ttttgggatc aagaacaaaa agctcggcat cagattttaa taaagcctcg atgatagtga
     2761 gtaaaaagta agtcttccca ccacctgtgc cgccagcgat taacatatga ggtaaagaat
     2821 cataagccca tacttgattt ttcatcaatc gcaaagcccc actttctgcc actacttcgt
     2881 ctatcccaat tcgattggca attatatcat acagtaaagt gtactccaca taggagtctt
     2941 tgagttcctt ttctactagt tcacaatata gaccactttc taacttcttt tccagcttta
     3001 aaagctgatc ttgatatttt cccagtgaaa tttgaacgcg aatagaaagt aaaccatcct
     3061 tcatacggta atagattttg gggaagtaac tgattgtctc tttggttcga ctactattga
     3121 ggtctttgaa aaatccttca ctctgagttt gttttacttc gtaccaatga ttttctagaa
     3181 tcatccgggc tagcttttgt cgatgccaca aactgcgcca atgatcctga aaaaagtgta
     3241 tataaagcaa catcgtgctt cctgaaagaa cgagacttcc tagcaaatag attaaatctt
     3301 ttatagaacg aacgatttct atagtagaaa gtgatagctt agaaatatca aattgtctaa
     3361 gctcttgaaa ataaaagacg ctcatccaac cgatgaacag agcgagtagc cagccaagaa
     3421 caaagtgata aaccaagtgc tgatctcctg cccgtatacg atgccctttg tacattttta
     3481 tggtttccac ctccaatcga aaaaagcttc ataggatttc attgatccaa tttcaagcag
     3541 ttatgctagt catttactgc tatagggagt tgtttcgttt ccactagttg ctttaaaaaa
     3601 acttcaatgg catccggcat ttccacacca atttcttcca atacggtttc ggcttctcga
     3661 catagacttt catttacttc gataaccata aagaaggact cttcttcccc taaccaattc
     3721 agtacatcaa aatcttcttc gacatcgtta cctacttcca gtaacccttg atgcataatc
     3781 agaaacattt tttcatcata ggttaatgct ttagtgagtt gttcctccgt tagctcacct
     3841 tttccatatt gatcgagaca atctaaaata tgttcaacat taatttccat acgcttcacc
     3901 tatttctttc cttcattttg gtttgtagaa tttccctgat ctggttgtcg tttcaagact
     3961 aaatcatcgg ccttaatgaa ccaattgaca gtagttcctt ctcggaaaac ataattggcg
     4021 accgtatcca tgattggatt gaccaactct acctctgcgt cataggcaaa ctcgcgtaag
     4081 ggtacatttg ctgggatact aacttggatc attcgacctt gcgcagagga tttcaaatta
     4141 taagtccgtt cttttacctc gttactaacc gttccatcct cattttgctt ccgtacttct
     4201 cggcgtaatg cggaaaatcg taatttccca aacgttagtc ctgaatctac aacaatacct
     4261 tctgttaatc tcatcttctt ttcctcctat gctttcacta aatcatcgac atacaacacg
     4321 tagtcggtaa acccacgatt ctcaatctca tagcctttgg caaccaaatg gggattcacg
     4381 gcttttagtg gttgatcttg atcaaaatcc ttttcgccgg cttccgcagc taccaccact
     4441 tcaatatcat cggctcgttg cttactggaa tacaaatgat aactacgacc aattactgta
     4501 gtattccgcc catatccttc agttaaaact tcgccttcgc cggcatacct tatctttcca
     4561 aaggtttcgg ccatatctgg cacaacaaat ttcaattcca tcttcttttc ctcttttcat
     4621 ttttagtttt ggatacaaaa atagcgcgac cacttttttt aggaggcggt cgcgcacgtt
     4681 ggtttttcct atttagttgt ttcatcacat caccttagtt tcggcgattc cagaaataat
     4741 acccagcagt cgcaaagatc aaggtaaacc caataaacag cagaacatta gaatttttct
     4801 cccctgtttg tgggaatgtc tttactgtag gactagattc ttgagagtca cttggaacag
     4861 ttggtatttc cggttgttct ggtgcacttg gtgttgtcgg aactttttta ggtgttaaag
     4921 tttgagtttt ttcttttaga tcctcattgt gtttcccatt gatgtttccg tctttgccat
     4981 agttaatttc tttgaaggta aaacttgtac cttctggata tttacttgtg tccacttttt
     5041 ccgcaagtac ggttttagtg aattctttgt cattcacttc ataatcaatt ttgccagatt
     5101 tccaaatttc tttggtcgta ttatccggaa gtaatgcata cagaattgtt tcaaaagctt
     5161 cttttgagcc atccagtaca tcatgggtaa tcgacacatc atcgaacata tccaccacat
     5221 ccccatgagt aaaggtttgc gaaccatctt ctaggtgggc ttttgtttgg atggaaacat
     5281 ggcgttccac cgtacaattg acagtttggg cttgattgtt caagctagca tctttcgcta
     5341 ctggatcatc acctgcttca tagggtttct tgttttcata cacatagttg aataagacga
     5401 tggttttatc caaaacttgt tctgcggtta atttatgcaa aattttccaa gttcctgttt
     5461 tctctttatt cgccaacgtt gcggttgttt cggcaattac cactggtttg gctttttcat
     5521 ctttttcttg ggcagctttt gtcgcttcca catcaatggc ttgcgctacc acataccagt
     5581 cttctttgat ttcatgcaag ttatagctca atttatcaac tagctcggta gaatcaaggt
     5641 ctgtcaattc tttgcctccg tctttccaag tcccaagaga agttaagcta tcttcttctt
     5701 caggtaaatc atagagcatc aaacgattca agctaacaga aaatgcttta ttcgtcagtt
     5761 tctcgtaagg aacggtcacc gttttaattg gttgtttttg tcctttttcg gtaatcgtaa
     5821 aaatgtattc actcttagtg taatccgctt tattttcttt aaaagtagaa cggatttcta
     5881 atggcgtaat tttttgaaat ccttctggag cctctacttc ttcaagtaaa taatccccat
     5941 aaggaagatt ttcaaacttg ccatagccat caaaacctag ttgctcgtta taagctgtaa
     6001 ttgcttcatc ttcggcacct gtaatctcac tggttccttc caatggcgat actttaaagg
     6061 tcagatcatt gaagccagtt tcggcagtcc cagcagctga tccagcaaat ttaaagaaat
     6121 caaagccaaa gcgaatgact tgttcttttg ccgtaacatc tcgggtaatc acggcatttt
     6181 tttcgttatc atccaccttt ttgatggaaa cagggtactt tgtttcatcc aaggtatatc
     6241 cttcaggtgc tttggtttct tgccagtaat actcattaat cgctaagtgt ttaacagcaa
     6301 cttgattctt ttcatctaaa gtcaaagtca ccgtttcatc agaagctttc gttcccttca
     6361 ctaactctgg tttaaaagcc tcactccatt tgaccgcttg accatctttt gcagtaaaga
     6421 gagtatattc agctccttta aactcagctt taccttgagt ttcattaccg gtatctttgt
     6481 cttcttttgt caaagtggtt tcaccagtga tttcttggtt ttgccctttt acgttactgg
     6541 taacaagagc cacggtttga ttgacatagt tcaattcgac ttttactggt ttaaaggtat
     6601 tcacaaagcc attactagct ttggtttcgg tcacataata ggttcccaat tccaacgcat
     6661 tggcaatctc ttttggtgtt tccgcatgac ctttttcatc cgtggtcatt tcttggacaa
     6721 tttcaccggt tggactgtct ttgcgaatgg caaacgtatt tccggctaat gagtatttgt
     6781 cgttccaaag atcagttcct gtttccaccc ccattttatt caaaatgatt tgaccttttt
     6841 cgcgagtatt ttttgaagtc acagaaatag tctcaccaga tttaatggtt gcggtgattg
     6901 gtgtagtgtc aatcgtataa ggagctggca ctgatttttc agtaatggtt actttcgcgc
     6961 catgaggaat ctcatccaat gtcgcaatgc cttctttatc ggtggtcacg tcttttgcag
     7021 gtaatgtttt tccaaagtct aaatggaaaa cggttcccgg tacaacattt cctgtttctt
     7081 tatcgacttt tttaatcttc aaagaaccct cagtttccac atcaattttg attgtgtagg
     7141 tattgggctt atcaattgcc cccgccatca aagtttgttg accagccatt ttataagcta
     7201 ccggtgttcc tgtattagct gacttcttta gggttaattc accactctct tttgaattgg
     7261 catttggagt aatcactagt tgattgccgt tcacacgata atcaatattt gcgatattct
     7321 cgacaacttc atcaaactcc gataaattca agccgttcgt atctgtcaca gtagtcgatt
     7381 gacctaacac ggttttcact gtggagttat ggaagcttgg tttcttttga taatccgcaa
     7441 tggcttgatt gatttttgac tcaatggctg cgatatttac tgcactacca tcagaacgtt
     7501 taattgagtg aagcgtgtag ccattaactt cttgccaaat catcttctgg gccacaatat
     7561 gtgtatccac atccgtacca gcttccttcc ataaaacgga aactaatttc gctttctccg
     7621 acatatcagg caatggattt ttctcataac caggagtgaa ctcattgtaa atcggcaccc
     7681 ctggctcaat acagaaaata tcttgcttca caccattgta aactgcatag tgcggaacgg
     7741 taacttctga catgggacga ccatcgctaa atgtaccttc gacagcatac tggtgagcca
     7801 aatccaattc cacagttacc gtttgtggat gagtaatttc atcagcaaag gcaatcgttg
     7861 ggccaagcga tccaccaatt gtttggcata atagactcag tgttgcgagc aaacgccaat
     7921 tcttaaatct tggctttttc ataaaataaa tctcctttcg tttttgggta ataaaaaaga
     7981 cgtccaaatt ttaattttga acgtctgatt tagagtgata ctatttagtt ttctttgtct
     8041 tggataggtt gtttctctgc ttataaattt tgattcttcg ataatcaaat ccaatctctg
     8101 ccatcaattc ctcccaattt ttgttcgttc ttttcataat tgtatcaact gatggtagtt
     8161 ttggggattg aactagtttt cgaaactttg tcattgataa atcatcctgt agttttaatc
     8221 ggattatttc attttttagt tctaacagca gttcgaaatc agtaaatcga gatccatcat
     8281 ttttttcttt aaaaagtgga cgtatatctc ctaacatctt tttaatggta ctaagtgaag
     8341 gaatattctt ccctactgat ttttgttcgt acattcgttg agaggttatc ttctcgcact
     8401 taataaaggc ttctactatt tccaataatt cttgttctga cattctagcc cattttccat
     8461 acccagtatt ttctcgtcct atactaatca ataaattctc ccatgatcca tattttttgt
     8521 taatgaacca catacttggt gcagaatttg gattttctga tagctttttc tggtattgac
     8581 ggctagatgt aattccgtgt ttttcgatga attcattaat tgttaaaatc agttttaact
     8641 cactttgatt tttccaaatg atacgtccat cattttgctt cacgataaaa actcctaata
     8701 gttatttaga tagaagccta tcacatcaac tttttagtag aaaagtacat gttttgtctt
     8761 ttttgctaat agctgaccct ttgagaaact tgggttcaaa agttgctaaa ttcggtaaat
     8821 gttttggtat ttttcgtatt atatttgtcg tcaagctgac tactaaattt tgccctattt
     8881 tgacgacact gatagtcaat gtcggacaat ctaggacaat ttttaaggga atatgattga
     8941 aaaatggtcc aaaacagcca aaaatggctt aaaactgtga tagagaaaaa agaaaaagcc
     9001 cttgatatac aaggactttt cacaaatttc agatttccaa ggaagttttc cgtgtttatc
     9061 ttctgatttc tttgatacga gcagcttttc cgtgtaatgc acgtaaacaa aaccactata
     9121 ttctattatg tatctaacac cctcaaaaca gctataaatc aacaataccg acataaaata
     9181 aacactatgt tcaatctgag atatatcaaa ggtaaacgca tttttgcccc ctttttgccc
     9241 ctcaaatatc gctttacaac aagaacgtaa gttcgtataa tcgttttgag gtgattttta
     9301 tgatggaaga atttattaga aaaaatatca gtgatgaata tgcagacttt tatgatcaaa
     9361 gcagtaaaaa agataaattc cagatggatg tttcaatctt agctatatta gctttttccg
     9421 aaaataaaca acctgtaact gcaaaaaaag aaacagtatt ctctgaaggc aaaataaaaa
     9481 ctcga
//
LOCUS       DAFENC010000072         9444 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.076, whole genome shotgun sequence.
ACCESSION   DAFENC010000072
VERSION     DAFENC010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9444
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.076"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            59..205
                     /locus_tag="LP493_002592"
                     /pseudo
     CDS             59..205
                     /locus_tag="LP493_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
     gene            282..611
                     /locus_tag="LP493_002593"
     CDS             282..611
                     /locus_tag="LP493_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL2134701.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            601..888
                     /locus_tag="LP493_002594"
     CDS             601..888
                     /locus_tag="LP493_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBL2134702.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKVIPVLLCGTHENFYEQLKKLI"
     gene            1174..2031
                     /locus_tag="LP493_002595"
     CDS             1174..2031
                     /locus_tag="LP493_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBL2134703.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYVEVE"
     gene            2032..2580
                     /locus_tag="LP493_002596"
     CDS             2032..2580
                     /locus_tag="LP493_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134704.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            2840..3473
                     /locus_tag="LP493_002597"
                     /pseudo
     CDS             2840..3473
                     /locus_tag="LP493_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
     gene            complement(3518..4467)
                     /locus_tag="LP493_002598"
                     /pseudo
     CDS             complement(3518..4467)
                     /locus_tag="LP493_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300609.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
     gene            5069..6913
                     /locus_tag="LP493_002599"
     CDS             5069..6913
                     /locus_tag="LP493_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL2134705.1"
                     /translation="MNYKQTAEEVLQYIGGEENISHLEHCSTRLRFTLKDNSKVNMSQ
                     LEKVDGVMGVRQNVQCQVIIGNDVVEVYDEVKALLGDNVSNTEEAPKQKQKLGSVLLD
                     FIISIFQPLIPAIAGGGVLKSLLLLASILGLISDQSQTYQILNLVGGAPLYFLPILVA
                     MTTANKLKVNQLVAVSAVGALILPEMTAMLAEGATFLSFGLDNIAYASQVFPAILTVL
                     FYAQLEKWFTKVSPKPIRIFFVPMMSLLITVPIALLLLGPLGYNVGTAFSSIIVSLYN
                     QFGWVATGVLAAVLPLMVVTGMHKAMIPYAVSSMSELGAELLYLPASLAHNISEAGAC
                     FAVSIKTKDKKLKSTAVSAGISALFGITEPALYGVTILHKRVLYAVMFSSLIGGAFAG
                     IVALQAFALVGPGIASITMFADKADPMNLVWAFAVSGISFVVAFAAALVLYKDKEVVN
                     EVETKMETAVVSDAVLSSPVNGKVISLSEVKDTVFSSGMVGDGVAIIPEEGILVAPED
                     GEITMVFETKHAIGLKTANGAELLFHIGIDTVQLEGKGFEAFVRSGEKVAKGQKLIAF
                     DIDLIKEAGFDPTVICVVTNKDNYTIRSFNLEKLVTNDSDLLAISPIA"
     gene            6969..8435
                     /locus_tag="LP493_002600"
     CDS             6969..8435
                     /locus_tag="LP493_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016620473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBL2134706.1"
                     /translation="MTNTTSFPKGFLWGGAIAANQVEGAWNVDGKGLSVADMATYKPN
                     LDNKDFAAHMHVTLQSIKEASEDKSDKWYPKRRGVDFYHHYKEDLALFAEMGFKTLRL
                     SIAWTRLFPTGEELEPNEKGVAFYENVFKEMQRLGIEPIVTLSHYEMPLALAVKYNGW
                     VERRVIDDFVRFANVCFDRFGKYVKYWLTFNEIDSIHRHPFTTAGIIQEKSAEGQEAQ
                     DIYQALHHQFVASALVTKDAHEKIPGSQVGCMLTKLMTYPLTCAPEDVELTLKKNLEN
                     NFYADVQVKGEYPALIEKDLENRGIQIKMEDEDREILKKHTVDFVSFSYYMSMAESAD
                     PNAERTPGNTVLGVKNPHLPSTDWGWQIDPKGLKISLIELYDRYQVPLMIVENGMGAV
                     DQVVDGKIHDPYRIDYFKAHFQQMKEAIDEGVDLIAYTSWGPIDLVSAGTSQMSKRYG
                     FIYVDADDEGNGTYNRLKKDSFNWYKEVIETNGASLFE"
     gene            8472..9314
                     /locus_tag="LP493_002601"
     CDS             8472..9314
                     /locus_tag="LP493_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL2134707.1"
                     /translation="MISIKKVLNSSVVLVEENGKEMIALGKGIGFGQKAGDEISGDKV
                     DKIFLPFEEKKSSQLLELVEEIPIEFFEITRTIVFEAEKGLDKKLNPGVYLTLTDHLH
                     FAVERAQKGVNIANRLYWEIKIYYPKEFQIGKYALTLLNEQYGIDLPKEEASNIAFHL
                     INAQSEDPDSGAGFKYAKMIGGIVNLVRYSLQKDIDTNSIHYARFITHVRFFVERYYS
                     DALLDDGEEEFYNQMWILYPSAMESAAKIKDYIEKVYHKTIPNDEVVYLGVHINRLMK
                     HANG"
BASE COUNT         3246 a         1443 c         1906 g         2849 t
ORIGIN      
        1 agcttaaatc atagataccg taagggattt tattctttat ttaaaacttt gcaacagaac
       61 ccaatcattt gagaagttaa aacctacaca tgaaggtagg tattttagaa gattgaatag
      121 acaacaccgg gttgtttata aggtagatga agatgaacac gtggttgaaa tttattcagc
      181 aaggacgcat tacgagtcac agtaattact tgtaaataca ttatctcgtg gtataatgta
      241 tttactaagt aattacatac tgttagaaat gagggattta aatgattaca aaaacaagaa
      301 aacaaggcaa ttcaatcatg ttgacagtac ctaaagattt taatgttcct aatggagtcg
      361 aagttgaagc aaagttggta gagaatggta ttctttatga atttgttgaa ccacaaaaag
      421 aattttatga ttttagcgaa gatattttgt ctgatataat tgcagaaggc tacgataaag
      481 atgagattct tgtagaattt aagaatagaa aaaacaaaat gcattcttcc tttagagata
      541 ttgctgaaga tacacttact aattctaaag taatgactaa agaggagttg gcaacagaaa
      601 ttggcttatg aaatcgttcc ttcaaaacat gtcattaagt atttaaaaaa gctaaaagag
      661 aagccattga aagaaaaatt tttgaattta atttatgatg aaattgcgat tgatccatat
      721 aagggtgaac aaaaaactgg ggatttatca ggtatttggt ctagtgggtt caaatatgcg
      781 ggcacaacat atagagtagc ttacgagatt atagaaaaca aggttattcc agtattgtta
      841 tgtggaacgc atgaaaactt ttatgaacag ttgaaaaaat taatctagtg atttgttgtc
      901 gttcttaaga aggacggctt cttttttatc gaaaatctga ttcgtctaca tgactaaagt
      961 cgcgagtatt ctctgcttct cgataaatta aataacgtca ttactttgag gaaagctata
     1021 aatcaatata tttcagcttt tccttattta tgtactacct tttacttatt aattataagg
     1081 tagtacatat atatcttttt tttggtagta actaaaaata aatatgttat aatagtatca
     1141 aatgaatatt gctaaaagaa aagaggtagg aacgtggtag cgaagaaata tgtaatcggt
     1201 aattttaaag gtggcgtagg taaaagtacg tgcgcgcaaa tgttagggtt tgaatcagca
     1261 gttaatgaag gaaaaagaac cttgataatt gacttggata tgcaaggaaa tacttctgat
     1321 gtgatgaact taacgcatat gaacttcact aacgaagaag gaggcggaga aggtgaaccg
     1381 attgtttacg aaaatactgt gactgacgtg ttgataaaca atcttccacc taaagaggct
     1441 gtctataaag taatcaataa cctctatata cttccagcag acatgtcctt tgaaatgtat
     1501 gatgattgga tcaaagacca atataatgat tcattatccc aattcaaata tatgaaagaa
     1561 aagctagaac cattatttga tgagtttgac gtcatctatt tagatgtccc accttctatt
     1621 tctgtatata gtaaatccgc gatgtacatt gcggattggg caatcgtcgt cttacagacc
     1681 caagtaaaat cgatgagaaa tgcgatgcaa tatcttgagt atatggactt ttttgtgaaa
     1741 gaatttgata caaatttata tgttgctggt gttattcctt tcatgttgga aagcggtgac
     1801 gcagtagatc aggaaatgta taaacaagcc caagagattt atggggaaca tttgattaaa
     1861 aatgttgtac tcaaaaatgc gcgcttaaaa cgatacgacg gatcaggtat tacgatggag
     1921 aagacaaaga aaggtctctt aaaacaatgg gatcgcaaaa gccacgaatt atttatcagt
     1981 attttgaaag aattggaaga acacgagaat tggtatgtgg aggtggagta attggctgac
     2041 atcaaaggac ttgatatttt tgggaacaac aaaggactcg ccaaaataaa aaaagaagca
     2101 gaagcaaaga aaaagcagca agcaattaca ccatctgaaa ataagcaatt agaagtgcac
     2161 caagttcaag aaataaaaac ttcctccaat gttgaaagac agagtagagg aagaacaaaa
     2221 aaagttggcg caccaatcag aaagtttgat aaggtttatt ccaccaagca tcctttaaaa
     2281 ctgtcgactt tgttaaatgc gacttccaga gttttagtag aaaagtatga gactaatatg
     2341 acaagagatg aattgcttag aaaagcttta gatgagtata ttaaacagaa tcttacgcaa
     2401 gaagataaac aagatttgtt taatgacgtg gtgaaagaac tagacttgtt cagagaaaaa
     2461 tatccaattg ttccagaatt agatgatcgt ggagaaataa taagaactac cagtcagata
     2521 aaacaagata ccgaagactc actgcgcaaa gggtggggaa tgaataataa agttagataa
     2581 taatcaaaga agaactaagt aactaccttt aaacggtagt tacttagttc ttctttgatt
     2641 tgcgtgaaat agaggggatt tatttttctg gttacgtgat taaaaaatcc aaaaaatgag
     2701 cataggaacg gttatgattt tagggtgtgt tttaatgaga tattgtgatt tcattaataa
     2761 gtgtatgata atctgttgtt gagttagtaa ataagtaata gagctaactc taaaataaaa
     2821 ctattaggag gagatgtaga tgaaaaagtt taaaaagaaa atatatttag gattggttgt
     2881 tggggtgagt atgtttgggt tcatggctca tactaaacaa gtaactgcag atactaacca
     2941 aaaagaaagg attatgagcc aattagatga ctctcaaata gagtatgtac ccaatgagct
     3001 aattgtcagt ttaaaggcta cacaaagaat ttcaacagag aaaaataaac cgcaaaattt
     3061 attgggtgta aaagttatgg tggaaaaaga tttgactctt aggacaaatg aaagcgatta
     3121 taataagcga gatcaagtat tattagtgaa attgaacgaa gaaattagtg tggaagaggc
     3181 agtaagaaca tttaatgctt ctgatatggt caattatgca gagccaaact atgtggttga
     3241 actagagccg ttgaatgatg ttgaggagcc aaatacaact gattctttag gaaatcgata
     3301 acgatcctaa ttggagtaaa caagctaatt taagagagat tagcatgcca tccgcttggg
     3361 aagaaaccaa gggttctaag gatgtgaagg tagcggtcat tgattcagga attgattatc
     3421 aacatgaaga tctttctgga aatgtagatg aaagtttggg atacgatttt ttttactttt
     3481 ttcaagaaaa taataattca gaatattctg actatattta tgcaacacta gtgactttag
     3541 gagaaacatc aatagccttg ctaaagtttt tgctttcgct aaagagagta ttttcgataa
     3601 tttgtttttt tctaaaatac ctcgttcctc aatatttggg atatggatat gtatagggat
     3661 tcttcgcata aaggtttcca gaaaatcctc tttgccttct gtagtcgcaa aaactaaacg
     3721 tacattggag gcgtgatgga tagtttcacc gactctagaa taagttccgc catccatata
     3781 aacaaatagt ttctcttgcc cttcaggagg caatctgtgt acttcgtcta aaaacagtac
     3841 tccaccgtct gcatcttgca acaatccatt tcgatcttca tctgcgccgg taaaagcacc
     3901 tttaacatag ccaaatagta tccccgacaa taattcagga ttattatggt attgcgcaca
     3961 attaagtact ttaaaaggag cattctcatg aataacgttc acttttttca taaactgata
     4021 agcagtatga acaaaaaaac tttttccaac tccagtatct ccagtgatca tcataggaag
     4081 ccctcttcca ggatagaaga cagcagtttt catttgttcc accgcatcgg ataagctcat
     4141 atcataccca atcatctttt gtagaatgga atctgtagaa ttgggctcca agtctgtttt
     4201 taattcagat atactttcgt atacatcttt taccggaatc aaaaagtgct cttcaaagcg
     4261 ctctttgatg gcaaataaca ctggacgagt attgatttta aatagaacgt tctttgcaac
     4321 taagtcattg gcaagtttac tggcatttgt tcttcccgtt cttaaaaatt gcgacaggtc
     4381 atttgtgtca aaaaagcact cttctaaatt actgatgcca atttcttcac attttgtgtt
     4441 tgcataagtc actatatcat ttttcatctt ataaacagtc ctttctaaac ttctatccct
     4501 taaataaata gcaaaaaaaa ggaagcaata tcgatatgct gtcctcttaa tttaataaag
     4561 cgctaatcta attcactgta ttatcatttt ttagtagtat agcacaatta tgaatgcctt
     4621 ttctttatat caaataaagt ttatataaaa aacctcatcc tgcaagaaag aaaaaatgaa
     4681 cccattcttt ttatactagg tcttaaaaag acagaacatc tgctagaaga tagaagagaa
     4741 taagagttat atatgttgga agatattctt agaaaaaaga caaaactttt agaacacgaa
     4801 aactatattg aacgaataaa atgaaaaaat gattaaaaaa tcattttatt atttacgttt
     4861 acattctaat atgttaaatt gaatataact taaacaggca tgtgactggt aatgcaggca
     4921 ggacctaaat aagttgaata acaatgtatg cgtttcaata cacgtttgcc ttgttgtcaa
     4981 tttatttagt ttctgcctgt tttttgtgtt gaggatggcc acttcgactc aaaagttcat
     5041 cactcaaaaa agaaaagagg gaaacaccat gaattacaaa caaacagcag aagaagtatt
     5101 gcagtacatc ggtggggaag aaaacatatc ccatttggag cattgctcaa ctcgtttacg
     5161 ttttacgtta aaagacaaca gcaaggtaaa tatgagccag ttagaaaaag tggatggcgt
     5221 tatgggcgtt cgccaaaatg tgcaatgcca agtaatcatt ggaaacgatg ttgttgaagt
     5281 gtatgatgaa gtgaaagcgt tattaggtga caatgtttca aatactgaag aagcaccaaa
     5341 acaaaaacaa aaattaggtt cagttctatt agattttatt atttctattt tccaaccttt
     5401 aattcctgcg attgcaggtg gaggagtatt gaagtccttg ttgctactag cttctatctt
     5461 agggctgatt agtgaccaat ctcaaaccta tcagatttta aatttggtcg gcggggcacc
     5521 gctttatttc ttgcctattc tggtggcaat gactacggct aataaattga aagtcaatca
     5581 attggttgca gtatctgctg tcggtgcatt gatccttcct gaaatgacag ctatgttggc
     5641 ggaaggtgct acattcttat cttttggatt ggataatata gcgtatgcat ctcaagtatt
     5701 cccagccatc ttaactgttt tattttatgc tcaacttgaa aaatggttta caaaagtttc
     5761 accaaaacca attcgtattt tctttgtacc tatgatgagc ttattgatta cagttcctat
     5821 tgctttgttg cttctaggac cattaggtta taatgtagga acagctttct cttctatcat
     5881 tgtgtctttg tacaatcaat ttggatgggt tgcaaccgga gtcttagcag ctgtactgcc
     5941 attaatggtt gtaacgggta tgcataaagc aatgatccct tacgctgttt catccatgag
     6001 tgaattgggt gcagaacttc tttatctccc ggcttcattg gcacacaata tttcagaagc
     6061 tggcgcatgc tttgctgtca gtatcaaaac aaaagacaaa aaattgaaat ctacggctgt
     6121 ttctgcgggt atatctgcat tattcggaat tactgaacca gctctttacg gggtaacgat
     6181 tctgcacaaa cgtgttttat atgccgttat gttttctagc ctgatcgggg gagcatttgc
     6241 aggaatcgtt gcacttcaag cctttgcttt agtgggtcct gggattgcaa gtatcacgat
     6301 gttcgctgac aaagctgacc caatgaatct ggtttgggca tttgcagtat cggggatttc
     6361 atttgtggtt gcttttgctg cagcgttggt tctttataaa gataaagaag ttgtcaatga
     6421 agttgaaact aagatggaaa cggccgttgt ttcagatgct gttctttcaa gtcccgtgaa
     6481 tggaaaagta atctcactat cagaagtaaa agacactgtt ttttctagtg gtatggtagg
     6541 tgatggagta gcaatcattc ctgaagaagg gatattagta gctcctgaag atggagaaat
     6601 cacaatggta tttgaaacga agcatgctat tggtttaaaa acggctaatg gtgcagaact
     6661 tctttttcat attggtattg atactgttca gttagaagga aaagggtttg aggcatttgt
     6721 tcgttctggt gaaaaagtag ccaaaggaca aaagctgatt gcatttgata ttgatttaat
     6781 caaagaagca ggattcgacc ccacagttat ctgtgtggta accaataagg ataattacac
     6841 tatccgttca tttaacctag aaaaattggt aaccaatgat agtgatctct tagctatcag
     6901 tccgatagct taaacacaag atagtgaaaa aaaatatatt gaatgaagga atagaggaga
     6961 atagaataat gacaaacaca acaagttttc caaaaggatt tttatggggc ggcgcgatag
     7021 cagcaaatca agtagaaggt gcttggaatg tagacggtaa aggtctttca gtagcggata
     7081 tggctactta taaaccaaat ttagacaaca aagattttgc tgctcatatg catgtcaccc
     7141 tgcagtctat aaaagaagct agtgaagaca aatctgataa atggtaccca aaaagaaggg
     7201 gcgttgattt ttatcatcac tataaagaag atttagcttt atttgccgaa atgggcttta
     7261 aaaccttgcg cctctctatt gcttggactc gcttgttccc tacaggagaa gagctggaac
     7321 cgaatgaaaa aggggttgca ttttatgaaa acgtctttaa agaaatgcaa cgtttaggaa
     7381 ttgagccgat tgtgacacta tctcattatg aaatgccatt agctttagca gttaaatata
     7441 atggctgggt ggagcgtcga gtaattgatg attttgttcg cttcgctaac gtttgttttg
     7501 atcgcttcgg caaatacgta aaatattggc tgacatttaa tgagatagac agcatccacc
     7561 gtcatccatt tacaacagct ggaattatcc aagagaaaag cgcagaaggt caagaagctc
     7621 aagatatcta tcaagcattg catcatcaat ttgttgcgag tgcgttagtg acaaaagatg
     7681 ctcatgaaaa aattccagga agccaagttg gttgtatgtt aacgaaattg atgacttatc
     7741 cattaacttg cgcaccagaa gacgttgagc tgaccttgaa aaagaactta gaaaataatt
     7801 tttatgcaga tgttcaagtt aagggagaat atcctgctct aatcgaaaag gatttggaaa
     7861 atcggggaat tcagattaaa atggaagatg aagatcgaga aattttaaag aaacataccg
     7921 tagattttgt ttctttcagc tattacatgt ccatggcaga atcagctgat ccaaacgcag
     7981 aacgcacacc gggaaatact gttttagggg ttaagaatcc tcatttgcct tcaacagatt
     8041 ggggctggca aatcgatcca aaaggtttga aaatttcgtt gatcgaactt tatgatcgtt
     8101 accaagtacc gttgatgatt gtggaaaatg gtatgggagc agtcgatcag gtagtagatg
     8161 gtaaaatcca tgatccgtac cgcatcgact actttaaagc acacttccaa caaatgaaag
     8221 aagcaatcga tgaaggtgta gatttgatag cttatactag ctggggacca attgatttag
     8281 ttagtgcagg aacttctcaa atgtctaaac gatatggatt tatttatgtg gatgcagacg
     8341 atgaaggaaa tgggacatat aaccgcttga aaaaggattc gttcaactgg tacaaagaag
     8401 tgatcgaaac aaacggtgca tccttattcg agtagtctcg atctttttaa gcagcgatag
     8461 ggggataatg agtgatttca ataaaaaaag tattgaattc aagtgtggta cttgttgaag
     8521 aaaatggcaa agaaatgatt gcattaggta aagggatagg ctttggacag aaagctgggg
     8581 atgaaatatc aggagataaa gtagataaaa tatttctgcc ttttgaagaa aagaaatctt
     8641 cacaactatt agagttagtt gaagaaatac ctattgaatt ttttgaaatc actcgtacta
     8701 tcgtttttga agcagaaaaa ggattagata aaaaactgaa tcctggagtc tatttaacct
     8761 taacagacca cctgcatttt gcagttgaac gcgcacaaaa aggggtaaat attgcaaacc
     8821 gtttgtactg ggaaataaaa atctactatc ccaaagaatt tcaaattggg aagtacgcac
     8881 tcaccctttt gaacgagcaa tatggaattg atcttcctaa agaggaagcc tcaaacattg
     8941 ctttccattt gatcaatgca caatcggaag atcctgatag cggcgctgga ttcaagtatg
     9001 caaaaatgat cggcgggatc gtcaatttgg tccggtattc gttgcagaaa gatatcgata
     9061 ctaattcgat ccattatgcc cgcttcatta cacatgtacg tttctttgta gaaagatatt
     9121 attctgatgc tttgttggat gatggtgagg aagaattcta caatcaaatg tggatcttat
     9181 acccgtctgc catggaaagc gcagctaaga tcaaagacta cattgaaaaa gtttatcata
     9241 aaacaattcc gaacgatgaa gttgtatacc taggtgtcca catcaatcgg ttgatgaaac
     9301 atgctaatgg gtgagcgctc agtaatacta ttgatgcttt taaaatcttt agagatggat
     9361 tatagtaaaa acaaggtgat ttccagctgt ttgttatcta taagagacat ttaaaaagga
     9421 ttaacgtaag ataataaaaa atct
//
LOCUS       DAFENC010000073         9317 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.077, whole genome shotgun sequence.
ACCESSION   DAFENC010000073
VERSION     DAFENC010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9317
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.077"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..2122
                     /locus_tag="LP493_002602"
     CDS             <1..2122
                     /locus_tag="LP493_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134708.1"
                     /translation="KKINAVLSLFVCITILFFSTNVINGIKTSEALYKNTAEIHMQYK
                     DDMDFNSYINALYEISTQENINISQYSFTAVNQLTILATNPNANKHWKFSKKNILARN
                     DSKVHYTNNKNSKYQLKLPNNFLNINIYPFSHVENIGLSEILYVQGNSNKLIPVLKKY
                     GTPTISNINQSDTFQINTNIVLVICYLSIFIVITTIIFAFSKMKEITLKKMLGYNSFD
                     TIKDSIKELNLLFCSLIITFILSIFLSIYYSNENFFLSFLLCSIFHFIISFLFIIVTL
                     SIYHLSSIKNYLKNSRPLKLNLCILNICLFLSMILLLIASTKVINTHNEAENNSLKYW
                     ERTTNLYKTNITNQLNRNNTVEENNYLKKASKFVYKIQKNYKTFIIAPYNYATIQENN
                     KEFFIGQKVYPNFEDYVSQPAGAGICVDLNYLKYYNPISFEESTDLNLINSDPLTTYI
                     LVPKKYKEYAKMIEKNYLEDIQFRLEDSPPQAPYKNPNLKNLKIKLIFVNNNQKYFSF
                     NTLYGKAKDNYTITDPIVRVINPEITESLFWGNILTSDGGLFFDQKHTSNQNFFNQIN
                     PYIKEFNLENIINFSYSVFQETGELLSQKKVNKLNAYLQYLLILGLFIIINFQMIFVS
                     FTINSKKIALKKIFGYSPISQVLDLCLLPFTIELFATMCFQLIFSKNTYLYFIIFMIF
                     LINLITSIIIYKKNSFKYFKENIL"
     gene            2119..2739
                     /locus_tag="LP493_002603"
     CDS             2119..2739
                     /locus_tag="LP493_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2134709.1"
                     /translation="MILSVENFTLSINKKKIKQNWNFSISEKDFIIVTGKSGSGKTTL
                     LNNLSLIDKQYTGNLFYFEKKVSKHDIQRLRRNHISYLFQNYALLENQTVQYNFELAK
                     KFNSNISNDHIYNLLTDFSLPKDILKEKIFLLSGGEQQRIALIRNMLKPFDILFADEP
                     TGNLDKENSTFIMNFLKNLTEKEKKAVVLVTHDLNVLNYGTNIIEL"
     gene            2853..2990
                     /locus_tag="LP493_002604"
     CDS             2853..2990
                     /locus_tag="LP493_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134710.1"
                     /translation="MILLKKEYEKFYDRLIYSLQLPKKLNRQLQKTYETKSTEEWESY
                     C"
     gene            3432..3812
                     /locus_tag="LP493_002605"
     CDS             3432..3812
                     /locus_tag="LP493_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HBL2134711.1"
                     /translation="MSEQNQNLASNSSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVASG
                     DAQRLSENLKIMQKELQKIWQQLR"
     gene            3794..4708
                     /locus_tag="LP493_002606"
     CDS             3794..4708
                     /locus_tag="LP493_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBL2134712.1"
                     /translation="MATIKVSRTTSCSRAINYAEPRATIKTGINCDVDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGKKFQAHGQAFLNKCYDLNDEICLAHNLPITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRIAIDQTMKNKKTRTYDQFCNSLKTLGIHCFNRGKNFTYELIHKKK
                     KVRSNRLGKDYEKETILHELDRRERTYNQQRTNELRRARASIRETAEEVRREQRTLTP
                     EQPEIRPARRNHEQHVERGTDHQQELSL"
     gene            4948..5637
                     /locus_tag="LP493_002607"
     CDS             4948..5637
                     /locus_tag="LP493_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134713.1"
                     /translation="MAFYLPYLLIFVSISGSIWLIYKIFQTRYSLKGSKIRFKRFFFL
                     GCIFSLIIVSSGLFGVLEGNKRVSRSILLGNVTQKYESARDKKKKEQALAQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYVKDTKI
                     EEACSDLFGDTNPWFASEEEKKEKQQSVTYERYEILLQQATNMQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(5758..5844)
                     /locus_tag="LP493_002608"
     CDS             complement(5758..5844)
                     /locus_tag="LP493_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HBL2134714.1"
                     /translation="MFELFICPLLVGVCVSLFSYWLNNRNKK"
     gene            6489..7226
                     /locus_tag="LP493_002609"
     CDS             6489..7226
                     /locus_tag="LP493_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015060391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBL2134715.1"
                     /translation="MSNDIVRYNNGLNSVPLRKFTPIDMDLFWGICSKMKRKGTKEEI
                     FTFKQIKELIDYNINARGDRFANDLIKMSKKIITLSFIYEDEKTYEQLNLFQKFKIDK
                     VNETLLIKVSEEFEYILNSIGTNFTRFELENMTNLKSSYVKELYRQLMAHKDRRSKKG
                     HWFVKIEDFRALLAIPESYRMRDIDKQIFAQAKKEFLNVNSTHPAIFKTFEIKKIKAY
                     KGNKIGSLQIYFEENIPSITLDNWLEK"
     gene            7254..7793
                     /locus_tag="LP493_002610"
     CDS             7254..7793
                     /locus_tag="LP493_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBL2134716.1"
                     /translation="MQPKETFTIKELSELFEISRQAISKHVDKLDPSLLAKNERGYKV
                     VLRSGVLQLASNLGNQRLLYRLHEYEQENDKNVYISSKNVIVNELLDKLREENEFLRE
                     QLSLKEQNNSNMQKLLDQQQQLTLQANQQIEKLQEQLQLAYTEETPEDESTTILSEET
                     ESIEKHTKKKKQKWWQLWK"
     gene            7809..7979
                     /locus_tag="LP493_002611"
     CDS             7809..7979
                     /locus_tag="LP493_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134717.1"
                     /translation="MTRKNLLFGSILLGILGFSPMLLSVINKGNKHGELKLNPNYYNS
                     PNEELFVKETDK"
     gene            complement(8291..8752)
                     /locus_tag="LP493_002612"
     CDS             complement(8291..8752)
                     /locus_tag="LP493_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2134718.1"
                     /translation="MEDLGSKLRELRVKKGYTQEYVARKFNVTRQTISKWENNKTTPD
                     IETLKKICEFYSTNINSILNEDNSKNKKNNLLVLTAIIFNIFVTILGLFELIQMNFFS
                     FTHGIFTWFALSGLIVIDILNYFYIYYSYLKNEKFFYTMFFPLVILIILLS"
     gene            8885..9259
                     /locus_tag="LP493_002613"
     CDS             8885..9259
                     /locus_tag="LP493_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HBL2134719.1"
                     /translation="MKKFLCLSALMGVLLTSGGIASATEALNLDVPEDHTAIYGGGME
                     ATEEGFSSSKLRYAAGGGDFNCGVNGFKVYANYYHARAKHSATAKNGRGGQVRSVQKA
                     GVRAYATCNATLTGNTGWWNVY"
BASE COUNT         3597 a         1414 c         1454 g         2852 t
ORIGIN      
        1 aaaaaaaata aacgctgttt tatcactttt tgtctgcatt acaatactat ttttttctac
       61 taatgttata aatggtataa agacttctga agcgctatat aaaaataccg ctgaaattca
      121 tatgcaatat aaagatgata tggactttaa cagttatata aacgctttgt atgaaatatc
      181 tacacaagaa aatattaata tttctcaata tagttttact gctgttaacc aactaactat
      241 tcttgctaca aaccctaacg ctaacaaaca ctggaaattt tctaaaaaaa atatattagc
      301 aagaaacgat tctaaagtcc attatactaa taacaaaaat tctaagtacc aattaaaact
      361 tccaaataat tttttaaata taaatattta tcctttttct catgtggaaa atattggatt
      421 aagtgaaata ttatatgtac aaggaaactc aaacaaatta attcctgtac tgaaaaaata
      481 tggaacacct actatttcca atatcaatca atcagatact tttcaaatta atactaatat
      541 tgttcttgtt atctgctatc ttagtatatt tattgtaatt actacaatta tatttgcttt
      601 ttcaaaaatg aaagaaatca ctctaaaaaa aatgttaggc tataactctt ttgatactat
      661 aaaagattct attaaagagt taaacctctt attttgttct ttgattataa ctttcatttt
      721 atctattttt ttgagcatat attacagtaa cgaaaatttt ttcctatcat ttcttctatg
      781 tagtattttt cattttataa ttagtttttt atttatcata gttactctaa gtatctatca
      841 tttatctagt ataaaaaatt atctaaaaaa ttcacgacca cttaagttaa atctttgtat
      901 attaaatatc tgtctattct taagcatgat ccttctgtta atagcttcta caaaagtaat
      961 aaatacccat aatgaagccg aaaataattc tcttaaatat tgggaaagaa ctactaattt
     1021 atacaaaaca aatattacta atcaattaaa tagaaacaac accgtagaag aaaataacta
     1081 cttgaaaaaa gctagtaaat ttgtttataa aatacagaag aattataaaa cttttattat
     1141 cgcgccatac aattacgcaa ctatccaaga gaataataaa gaatttttta ttggacaaaa
     1201 agtttatcca aattttgaag actatgttag tcaacctgct ggtgcaggaa tatgtgttga
     1261 tttaaactat ctaaaatatt acaatcctat ttcttttgaa gaatctactg acttaaattt
     1321 aataaactct gatccactaa ctacttacat tctagtacct aaaaaatata aagaatatgc
     1381 aaaaatgatt gaaaaaaatt atttagaaga catacagttt agacttgagg actctcctcc
     1441 tcaagctcct tataaaaatc ctaatttgaa aaatttaaaa ataaaactaa tatttgttaa
     1501 taataaccaa aagtatttta gttttaatac cttatatgga aaggcaaaag ataactatac
     1561 aataactgat cccatagtta gagttattaa tccagaaata acagaatcat tattttgggg
     1621 aaatatattg actagtgatg gtggattatt ttttgatcag aaacatactt caaaccaaaa
     1681 cttttttaat caaattaatc cgtatataaa agaatttaac ctagaaaata tcataaattt
     1741 ttcttattct gtttttcaag aaactggtga attattatct caaaaaaaag taaataaatt
     1801 aaatgcatat ctacaatatc ttttaatatt aggattattt ataataatta attttcaaat
     1861 gatttttgtt agttttacta taaattcaaa aaaaatagct ttaaaaaaaa tatttggata
     1921 ttcaccaata agtcaagttt tagatttatg tttactccct tttacaatag agttatttgc
     1981 tactatgtgt tttcaattga tattttcaaa aaacacttac ttgtatttta taatttttat
     2041 gatcttttta ataaatctaa ttacttctat tattatttat aaaaaaaata gttttaaata
     2101 ttttaaggag aatattttat gatattatca gttgagaatt tcaccctgtc aattaataaa
     2161 aaaaagatca aacaaaattg gaacttttca atatcagaaa aagattttat tatagtaaca
     2221 ggaaaaagtg gtagtggaaa aactactctg ttaaataatt taagcctaat agataaacaa
     2281 tataccggta acttattcta ttttgaaaag aaagtttcta aacatgatat acaacgtcta
     2341 cgaagaaatc atattagcta tttatttcaa aactatgctc ttcttgaaaa tcaaacagta
     2401 caatacaatt tcgaattagc aaaaaagttt aacagtaata tttccaatga tcatatttat
     2461 aatttattaa cagatttttc tttgccaaaa gatatcttaa aagaaaaaat ctttctctta
     2521 agcggtggag aacaacaaag aatagcatta attagaaata tgttaaaacc atttgatata
     2581 ttatttgcag atgaacctac aggaaattta gataaagaaa actcaacttt tataatgaac
     2641 tttctgaaaa atttaacaga aaaagaaaaa aaagccgttg tactagtaac acatgactta
     2701 aatgttctaa actatggaac taatattata gaattataat ttttacccgt gatgctagct
     2761 gatttaaaac tagcaccacg ggtatttatt ttatattcca tctctcctat cccaaaattt
     2821 aaataatcac ttaataaaaa ggaggcaccc aagtgatttt attgaaaaaa gagtatgaaa
     2881 aattttatga tagacttatt tattctttgc aattgccaaa aaaattaaac cgtcaattac
     2941 aaaagactta tgaaactaaa tcaactgaag aatgggagag ttattgctag atttttggta
     3001 gaagtaacaa aaagtggaca tattatcata atgactcgcc gaaagtctga taaaaaattg
     3061 gctaaaaata ttgctgaatg tttaataaaa ctatcagttt tagctaaata gttagtagtt
     3121 tacacaaaaa agcatttatg ttttttgttg caaagcaaca atttcatctt cggtgaaata
     3181 agcgaaactt tacaaaaagt ggctagcatt tgctagcttt ttttgtattg tggagcgtgg
     3241 cttttgaggg ggattcaagg gggagcttgc gcccctttga caagcggtta tttgcactaa
     3301 atacgtaggt atttggctag caaatataga gcttgccaaa cccttttagt gagctttact
     3361 cattgtacct ttttaggtac aatggtattg cgaacgatac gtccgtagga cgtactgaaa
     3421 gggtgggact tatgagcgaa caaaatcaaa atttggctag caattcttct aaaaaatata
     3481 cctatcgatc cgagccaaaa caaatcagtt ttcgagtgag cgaatccgaa tttgcaaagc
     3541 tgaagcaatc ggctgaagct ttgcaaatga gtgtgccggc tttcgtgaaa gccaaggcac
     3601 aaaacgcgcg tctggtgaca ccgaaagtgg cgccagacat tgcccaggca atcgcgcgcg
     3661 atttagccaa agctggaggg aatatcaatc aaattgctaa gtggtgcaat acacaccaac
     3721 atgacgttgc ttctggtgac gctcaacgtt tatccgaaaa cctaaaaatc atgcaaaagg
     3781 agctacaaaa gatatggcaa caattaaggt aagccgaacc acttcttgta gtcgtgcaat
     3841 taattacgca gaaccacgag caaccattaa aacaggaata aactgtgacg tcgattatgc
     3901 caaaagtgaa atgaaacaaa ttcgcatgct gtatggaaaa gacgaccgtg tacaggcaca
     3961 cttattgatt caatcttttc gaccaggaga aattaccgct gaaaaagcta atcaactagg
     4021 ggcagagtat gcaaaaaaaa tagcccccga tcaccaaata gctatttaca cacatacaga
     4081 caaagaccat attcataatc acattgtcat taactccgtt aatctggaga ctggaaaaaa
     4141 atttcaagct catggtcaag catttctaaa caaatgttat gacctaaatg acgagatttg
     4201 tcttgcacat aacttaccaa tcactgagcg aggaaagaaa ccagaaaaac gaaccatgtc
     4261 tgaaataaaa ttaaaagaaa aaaatgaacc tgtttggaaa gacgaaattc ggattgcgat
     4321 cgatcaaaca atgaaaaaca aaaaaaccag aacctatgac caattttgta attccctcaa
     4381 aacattgggg attcattgct tcaatcgcgg gaaaaatttc acttacgaat tgatccacaa
     4441 aaagaaaaaa gtacgatcca acagactagg aaaggactac gaaaaggaga cgattttaca
     4501 tgagctggac agacgagaac gaacctataa ccaacagcga accaacgagc tacgaagagc
     4561 tcgagctagc attcgcgaaa ctgcagaaga agtacgaaga gaacaacgaa ctcttacgcc
     4621 tgaacaaccg gaaattagac cggctcgaag aaaccatgaa caacacgttg aaagaggaac
     4681 agaccaccaa caagaattat cgctctaaaa cgttaaaaga catagaaaac gaaataaaga
     4741 aacaacgtgc ttttctcgtt ccttatacgc aagaaaggat acaaactacg attgatttac
     4801 aagttaaaaa actccatcaa gagctattag accagcgaaa taaggaacag aaaaaggtgc
     4861 ttattcaacg atcattggat tttcttgccc ccttatgttg cttagtcctg acactgttcg
     4921 cattttggtt agtatgggga ggctaaaatg gcattttatt taccctatct actcattttt
     4981 gttagtattt caggaagtat ttggctcatc tataaaattt ttcaaacaag atattcatta
     5041 aaaggctcta aaattcgatt taagcgattt ttctttcttg gctgtatatt ttccttgata
     5101 atcgtttcaa gcggcttatt cggcgtttta gagggaaata agcgcgtttc tagaagtatt
     5161 ttattaggaa atgtcactca aaagtatgaa tcagcgcgtg ataaaaagaa aaaagagcaa
     5221 gcattagcac aaaaaatgga agagtttacc acttgttatg aggaaatgaa cgatattttt
     5281 gtgaatcaag aaaaacgttt gacggataaa aacatggaaa aactcactcg tctttatcaa
     5341 aacttgccag aaaaacagca aaaagaggtt caagacaact atgagcgaac caaaaaagac
     5401 gtgcaatatg taaaagatac aaagatagaa gaagcctgta gtgatctatt tggagacaca
     5461 aacccttggt ttgccagtga agaagaaaaa aaagaaaaac aacaatctgt cacatatgaa
     5521 cgctatgaaa tcttacttca acaagcaact aacatgcaaa atccgacaaa aaaagaaacc
     5581 gccttaaact atctaaaaag tgtcaaggaa tggttagatc agcaacaaca aaattgaatt
     5641 tgatttaaaa tcatgttaaa ctgaatgtgc aaatgatcaa acattagata cacgaaagcc
     5701 ccagagaggt cggattctct ggggcttttt ttcaggttga tgtcgccttt attgatttta
     5761 cttcttgttt cggttattca accaataact gaataaagag acacaaactc ctacaagaag
     5821 ggggcaaatg aacagttcaa acattagata cacctccttc cagtcgcaag actgtcggat
     5881 aggcgacaag ttattatatc ttaaaaaatt aaatttgtgt ggtgttttta agtatcactt
     5941 gttttagggt tgttagggct tgccctgacc gcctgtaagg cgcttctcga ctagattaag
     6001 ggaaattaat caagaattgt cttagaacgg cttagacaag ctttcagagt ctcacacctc
     6061 ctctttgaac aacggtttta gcaaaggagc cggaggcgac tgcgcagtat aatatgagag
     6121 catagcgatc acaccttttt agcgaccgta gggagcaagt tttccagttt agaaaaattc
     6181 gcgaaccttt ttggaggaaa aagtaggagt tttttaggcg ggaaattcaa tgtgctctta
     6241 agatatactg ttagatatac tgttagatat actgttaata ataactgtta gggattagca
     6301 accttatggg agagtaagta ttgacatagg tagtggggga taaattgtca cactatgggg
     6361 gataaattgt cacactatgg gggataaatt atcacactat gggggataaa ttgtcacact
     6421 atgggggata aattgtgttt tacatcctct tatgtctatg ataacataat ttattgaggt
     6481 gatttttatt gagtaacgat atagttcgat ataataatgg attaaattct gtccctttaa
     6541 gaaaatttac ccctatagat atggatttat tttggggaat atgttctaaa atgaaaagaa
     6601 aaggtacaaa agaagaaatt tttacattta aacaaataaa agaattaatt gattacaata
     6661 taaatgcacg tggcgaccgt tttgctaatg atttaataaa aatgtcaaaa aaaatcatta
     6721 ctttgtcttt tatttatgaa gacgaaaaaa catatgaaca attaaatctg tttcaaaaat
     6781 ttaaaatcga taaagtgaat gaaacattat taataaaggt ttctgaagaa tttgaatata
     6841 tacttaattc aatcggaact aattttactc gtttcgaatt agaaaatatg acaaacttaa
     6901 agagtagcta cgttaaagag ttatatcgcc aacttatggc tcataaagac agaagatcta
     6961 aaaaaggtca ctggtttgta aaaatagaag attttagagc tctattagca ataccagaaa
     7021 gttatcgcat gagagatatt gataaacaaa tttttgccca agcgaaaaaa gaatttttaa
     7081 acgttaattc aactcaccct gctattttta aaacttttga aatcaaaaaa attaaagcct
     7141 acaaaggaaa taagatagga tctctgcaaa tttattttga agaaaatata ccttcaatta
     7201 ccttagataa ttggttagag aaataatacc taacaattta ggaggcaatt atcatgcaac
     7261 ccaaagaaac ctttacaata aaggaattat ctgaattatt tgaaataagt aggcaagcaa
     7321 tctctaaaca tgttgataaa ttagacccgt ccttattagc taaaaatgag cgtggttata
     7381 aggttgtatt acgttctgga gtattgcaac ttgctagcaa cttaggtaac caaaggttac
     7441 tatataggtt gcatgagtat gaacaagaaa acgataaaaa cgtttatata tcaagcaaaa
     7501 acgtgattgt aaacgagttg ctagataagt tgcgtgaaga aaatgaattt ttacgagaac
     7561 aactttccct caaagagcaa aataattcta atatgcaaaa attactcgac cagcaacaac
     7621 agctcaccct acaggcaaat caacagatcg aaaaactgca agaacagtta caattagctt
     7681 atacggaaga aactccagaa gatgaatcaa ctactattct ttctgaagaa acagaatcga
     7741 tagaaaaaca cacaaaaaag aagaagcaaa aatggtggca actttggaaa taactggagg
     7801 gaacattcat gacaagaaaa aatcttctat tcggttctat tttactagga attctaggct
     7861 tcagtccgat gttattgtca gtaatcaata aagggaataa acatggtgaa ttgaaattga
     7921 atccaaatta ttacaacagt cctaacgaag aattgtttgt aaaagagacg gataaataat
     7981 aaaaaagact gctcttccga gcagccagtt aaaaaataat gagtgtttat tcttgaaaaa
     8041 gcacgcgctt atgaagcgct accaaaaatt taccatattt tacaaaaaat aacaagtctt
     8101 aaaaaaatga cagataaaaa tgcacaaaga attagatata gataaccgcg aaaaatcaag
     8161 ctttagaaag ttgcttttag ctagaccaat taaaaatcac aaagtgagcg tctctatcca
     8221 ttggtagagg ggctacttgg catagtgtac attatgtcaa ctatgcaatt aaataactaa
     8281 ctacttcata ttagcttaat aaaataatca aaataactag ggggaaaaac attgtataaa
     8341 aaaatttttc attttttaaa taagaatagt aaatataaaa ataatttaag atatctatta
     8401 ctattaatcc agatagagca aaccaagtaa atattccatg tgtaaagcta aaaaaattca
     8461 tttgaatcaa ttcaaataaa cctaatatag taacaaatat attaaaaata atagctgtca
     8521 ataccagtaa attatttttt ttattttttg aattatcttc atttaaaata gaatttatgt
     8581 tagtactata aaattcacaa atttttttta gtgtctctat atctggtgtt gttttgttat
     8641 tttcccactt tgaaatagtt tgacgtgtaa cgttaaattt tcttgccaca tattcttgag
     8701 tatacccttt tttcactctt aattctctta gcttagatcc taaatcctcc attttttctc
     8761 ctatgtaaac gattatttac ataaaatttt atcataaaaa tactaacgcg ccaaaaaagt
     8821 tctttatttt ataaaacaca ctaaaataaa ataattctag taaaaaagat aggagaaata
     8881 agttatgaaa aaatttttat gtctttctgc tttaatgggt gtcttattaa ctagtggagg
     8941 aatagctagt gccacagaag ctttaaatct agatgtaccc gaagaccata ccgccattta
     9001 cggaggagga atggaagcta cagaagaagg attttcttct agtaaattga gatatgctgc
     9061 tggcggcggg gatttcaact gtggggttaa tggatttaaa gtttatgcaa attactacca
     9121 tgctagagct aaacatagtg caacagctaa aaatggacga ggcggtcaag tacgatcagt
     9181 tcagaaagct ggagtaagag cttatgcaac atgcaatgcc acacttactg gaaatactgg
     9241 ttggtggaat gtttattaaa aaagagagtt taaactctct tttttattta catttgaaag
     9301 gaaattcaaa atatgtt
//
LOCUS       DAFENC010000074         9003 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.078, whole genome shotgun sequence.
ACCESSION   DAFENC010000074
VERSION     DAFENC010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9003
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.078"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            121..1755
                     /locus_tag="LP493_002614"
     CDS             121..1755
                     /locus_tag="LP493_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134720.1"
                     /translation="MRWYMNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAF
                     HINRALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLY
                     IVTLITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPL
                     ILLGFIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIF
                     LIIKLIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDS
                     ELLSFGIGLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLN
                     IIQAPWRFMIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNM
                     VKEMNFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPN
                     KDEITFTFKSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTI
                     RYSYTFFSKISLFISIITLIVLLFYCIKLKIRTSHE"
     gene            complement(2022..3191)
                     /locus_tag="LP493_002615"
     CDS             complement(2022..3191)
                     /locus_tag="LP493_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBL2134721.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            3395..4570
                     /gene="mltG"
                     /locus_tag="LP493_002616"
     CDS             3395..4570
                     /gene="mltG"
                     /locus_tag="LP493_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HBL2134722.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            4706..5185
                     /gene="greA"
                     /locus_tag="LP493_002617"
     CDS             4706..5185
                     /gene="greA"
                     /locus_tag="LP493_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HBL2134723.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            5354..6085
                     /locus_tag="LP493_002618"
     CDS             5354..6085
                     /locus_tag="LP493_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HBL2134724.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            6082..7149
                     /locus_tag="LP493_002619"
     CDS             6082..7149
                     /locus_tag="LP493_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBL2134725.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            7156..7788
                     /locus_tag="LP493_002620"
     CDS             7156..7788
                     /locus_tag="LP493_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2134726.1"
                     /translation="MIKVLLVDDHEMVRLGVSFYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            7928..8593
                     /locus_tag="LP493_002621"
     CDS             7928..8593
                     /locus_tag="LP493_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HBL2134727.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            8621..8914
                     /locus_tag="LP493_002622"
     CDS             8621..8914
                     /locus_tag="LP493_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HBL2134728.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
BASE COUNT         3089 a         1337 c         1706 g         2871 t
ORIGIN      
        1 gaaacactac ttttgtaata taaaaaatat tttattaata ataaaattaa tcacatttta
       61 tatagtgact aatctagtgt ttaaaaaaaa taaatgatac tatatgtaat ataaaaaaac
      121 atgaggtggt atatgaattt gaaaaaaatt ttttctgtaa aaatatttat agtttatgca
      181 tttgttagtt tattatattt atttccagca tttaaaaaca tggaaatatt tggcttttat
      241 gatacggcat ttcacattaa tcgtgcgtta agtttagaat ctatttttag ctcccctatt
      301 aattttgaaa cgtttagatc atatggcatg caagtaaata atttttaccc atggttaact
      361 ctatatcctt tatttttatt gatcaagttt actaatttag caataggcta taaccttttt
      421 ctttatattg ttacgctcat tactctattt atatgtcatt atgtaatgta tgaaattacc
      481 aaaaaacatg ttactagctc ctttttcgct attatatata caacatcttc ttttaggagt
      541 gtagaaatat ttcttcgagg ggcaatgggg gaattactcg caatgtcaat acttcctctt
      601 attttactcg ggtttataaa gctttacgac tcaaaaaaag aatcttgggt tatgttggcg
      661 attagcatga ctttattaat ttacactcat gttctttctg tagctatgac tatggtaatg
      721 attataattg ctttaattat tcaattttat cggaaaaaga aaatagaaat cttcttaatt
      781 attaaattaa taaaagctgc tatagttact ttacttcttt cactagcgtt tataggtcct
      841 atgattgagc agacattgta tcaagatctg aatagacctt atgtggatat attacaaaaa
      901 agagcaattt atctgggtaa agagtttttg attggaagta tagattcaga attactatca
      961 tttggtattg gcttaacttt gcttatttgt ttaattatac taacatttaa ctttaaaaaa
     1021 ttaggaatct tatctaaaat cacttatata atgggtataa tatctattct actttgtaca
     1081 aaaatatttc catggtttgc cttacaaaat actcctttaa atattattca agctccttgg
     1141 cgttttatga tattttcaac attgttcata tctttttcag tatctctatt tatttctcca
     1201 cagttggaaa aattttctta tacaaggaga agaaatttta tactattatt aatattagct
     1261 atttcaattt taaattattc atcagtagtt aacatggtga aagaaatgaa ttttcaagga
     1321 acttattcta atgaacaaat ggaaaataaa cttgaagaat ttgagaattt tgattatgta
     1381 cctataggct ataaaaaaga tcaattgctt ttgaaaaacc atcaagttac agaagatggt
     1441 caagttattt atagtagctt ttctccaaat aaagatgaaa ttacatttac gtttaaatct
     1501 tcaaaaggca aaacaatagt tttacctgta ttccggtata aaggattaac ggttactgtt
     1561 aattcaaaaa atgctacagt actaaaacaa ggaggtcctt ttgttacagt aaaaagtgaa
     1621 agtggaataa ataaagtaac aatcaggtat tcatacacat ttttttctaa aatctcatta
     1681 tttatttcta taatcacgct aattgttctt cttttttatt gcataaaatt aaaaataaga
     1741 acaagccatg aatgatttgc tagcacatat tttagcaatc taaagatact attttagatt
     1801 taataggccc tttgtcaaat aatgttggta aagagaaatc ttagaataat ttggacagaa
     1861 cagaaagaag aacacctctt tctgttctgt ttatttggaa ttaaagtctg tagcaaaaat
     1921 tgatttttag atttgtccca cactctttcc tacgtttagt cgagtacttt ttttaagcaa
     1981 atgctattca aagaagtagt atttgctatc ttttcatcat atcagctatt tgccaactta
     2041 gtagttcctt ccatcaggtc atagatttgg tttcttagat cagcagtagg cagtttgata
     2101 gttttgtcag cttttatatt gctttccatg atgatagcat cctgtgaatc tttgctaaat
     2161 atagcagatg tatcaaaaga gtcgatattt ccttgcgaca ggatataatt atctccgcta
     2221 tataccccac cactatatgg atgtccattc gcattttcac gccataatga gaagagtaag
     2281 tctttggaaa ctagttttcc agataaaact tgtgtaaaca gcgtatttaa atcatagacg
     2341 gacatactga tattaccagt ccctaattcg ttatggatct ctgtttcaga ttctgtcagt
     2401 ggtttaaagt aatcatcctc tttagacatt tgataggata gtgcatgatt ggatgaattt
     2461 ttgacttggt cataaaattt tgtatgctgt aatcctaaag gttcgatgat atcatcggtc
     2521 aataattttt catacggttg atttgttaat ttgatcaaaa ttccagtcaa tatggtaaag
     2581 ttcaatgaat cataatgaga ggtctgataa tctgtaaatt ttaagtgctg aatcgcaaat
     2641 tgaacgactt cttcatcagt catcggtatg gttggagaag cagttcggtg caagcctgag
     2701 cgcatataca gcaagtcacg gatagtaatt tgctggctgc cagcaatttg tggatagaat
     2761 tgagccagct tagtatctaa agaaaggtgc ccacgctcga cttgttttaa aatcaaaaga
     2821 gtagtcaatg ctttttgaac cgaaccaatc tgataataaa gagaaggatc atttggttgt
     2881 tgcgtgagtt tattcgcata gccatagcct ttttccatga tgatgcgatt atttttcttt
     2941 acgtaaattg agccaatata atcatttttt cttaatagtt gatcgatttt ttcaacgagc
     3001 tgttgttcat tggtagtcag tatcaacttt ttttgagctg attgagcatg ggcaactatc
     3061 tgagagtgtt cattattgta aaattgccat ccaagaatag ttcctgtaga gaacgcacta
     3121 aggctaaaca acacgacaac gatcattaaa aatgaatatt ttcttttttt agcatgtttt
     3181 ccttttttca taatagttta tttagtctcc tttctttttt acagaaagaa taaagctaaa
     3241 atagcttgta tcttgataac atttatttta atcttatagt aatggattta ctacttacat
     3301 ttttgataga atatttaaat aaaatcattc acgccaattc aaatatcatg tataatgaat
     3361 aaagttacga acttgatagt aaggaggagt tgttttgtca ggaaacaaac aacacccaag
     3421 taaagataaa aaagaagcca gtaaggcagc tacagcagat ataatcgaca agcggagaaa
     3481 tctgcgtaaa aaagaagata agattgtgag gaagatcatt ttagtgattg ctcttacatt
     3541 attgattatt ggcggatttc ttggatttac cgtgtatcgt tatgtagata gcgggttgaa
     3601 gcctttagat aaatcagatg accaattagt ccaagtcgag atcccgagtg gctcttctaa
     3661 caagcagatt ggtgagattt tggagaagga caatattatt aaaagcggga ttgttttcaa
     3721 ttattataca aaatttaaaa atttaactgg ctttcaagct ggctattatc agttagcgcc
     3781 taatatgact cttgacgaga ttggcaaaca gttgcaagaa ggcggtactt ctgagccaac
     3841 aaaagttgca gatgggaaaa ttgccattcc agaagggtac gatatcgatc agattgctga
     3901 acgggtagcg aaggtaactg gtaaagacaa gaaagaattt ttagatttag tgaatgatga
     3961 gactttcttt aacgagttgc accaaaaatt cccagaactg ttggaaagtg catctaaagc
     4021 tgagaacaca aaataccgtt tggaaggtta cttattccca gccacatatg attattacac
     4081 gagtacttcg cttaaggatc tagtgattga aatggtgaac aagacgaata cggtcatgca
     4141 aaactattat tcagctatca agcagaaaaa tttgactgta caagaagttt taactctagc
     4201 ttctctagtt gaaaaagaag gcgtaaaaga aaatgatcgt aaaaacattg cacaagtctt
     4261 ctttaaccga atcaaagcaa atatgccact tcagtcagat atctctgttt tatacgcatt
     4321 aggtgaacac aaagaattag tgacgtatga agatacagct gtagattcac catataattt
     4381 gtataccaat accggctatg gacctggacc ttttgacaat ccaagcgaag aggcaatcaa
     4441 ggcagtatta gaaccagcag aaaatgacta ttattatttc gtagcagata cgagcactgg
     4501 aaatgtttat ttcgctaaaa cttatgaaga acatatggaa ttagtggaaa aatatgtaaa
     4561 taattcttag aaaaacaggc tctagacatt gatcattttt agaaaaacat ttacatttga
     4621 agaaaagcgt ggtaatcttt tttggactat attcctcaaa agattacctt ttgcggtatt
     4681 ttatcgaaaa aaggagacgt tacacatggt agagaaagtt tatccaatga ctctagaagg
     4741 taaagaaaaa ttagaaaaag aattagaaga actaaaaaca gtcaaacgcg gagaaatcat
     4801 tgaacgaatc aaaattgccc gcggtttcgg agatctttcc gaaaactctg aatatgaatc
     4861 agcgaaagat gaacaagcat ttgttgaagg aagaatcaca acaattgaaa atatgattcg
     4921 ttttgctcaa atcatcgata acgacggtgt agatgcagat gaggtatcaa ttggtaaaac
     4981 agttacattc atcgaactac cagatggaga agaagaagag tacacgattg tcggaagcgc
     5041 tgaagcagat ccgttttctg gcaaaatttc caatgattct cctattgcgc aagcattgat
     5101 tggcaaacgt aaaaatgatg aagtaactat tgctactcca ggtggcgata tgttagttaa
     5161 aatcgtcaaa gtagaacaag cgtagtctga ctgaaagatc tagagagttc atcttactga
     5221 tgatacactc tagatctttt tctctttgtg tattttagat ttcaacaaac gatcttacat
     5281 ctaaagtcct atagccaaca gttaaaaaaa taggtatgat gaaatgagaa tgtgtcagga
     5341 gggagaaaga gcgatgaata gttcttggcg tttttttgtg gtagttgaag cactactgct
     5401 gttatttgct gtttggcaaa tcgtaaacaa tactggactt ttgcttttag tgatattcgg
     5461 tattttcaat atatatctag ctatgcgcaa acatcctcgt actaaatttc aaaattttca
     5521 attgatatta ggaagtttgg tcattttttt tagcttagtc aacagtcctg ctttatggat
     5581 gatggctgta tttgccgttt tatttattgg tctgaaaggt gtagagattt cagggataga
     5641 tttaaccaaa aatgcttttt ggcgaaagaa acagatcatg atgatccaaa cagagcaatt
     5701 aaaaacacat aataatgagc ggaaaagaca gcaattattc ggtaaccaac gtattggaaa
     5761 cgacgtctat gaatgggacg atatcaacat cgccgtcatt tctggtgata ctatcataga
     5821 tttgggcaat acgcttttgc caaaagatga taatattgtg attgtaagaa aagggatagg
     5881 cagaacacgg atcttagtac ctttgggcgt agccatccga ttagagcatg cgacattagt
     5941 aggaaatgtc ttgtttgaag aagagcaatt ttctttgaaa aatgaacaaa tcaaaatcta
     6001 cagcagtgat tatgatgaaa accctcgtag attgaagatt attactaata ccttgattgg
     6061 agatgtcgag gtgatacgaa tatgatggga aaaatatcca gagcgatgct agctgtttat
     6121 tcggggattg cggctttcct tattattcta ttttcacttt tcacttattt ttatgccagc
     6181 aatcaaagtc attggtgggg agaattactg cgtgcacgtt tattatatgt tccgcttatc
     6241 ttccatttgt tagccatttc cttaggtgta ggattaattg tctttctatt attatcactt
     6301 attcaaaaga caaaatacgg gaaaatcgaa gaaaagctgc gtgcactttc ttctggcaat
     6361 tatgaatcca aattgttgct tcttccgatc ccaagtgcat cggacgattt atacatcaaa
     6421 gatattgata aggaaatcac taagataaaa gaaaaaatga ttgaagtatc tagtgaatta
     6481 caaattgtaa cgagccgtcc ccaatatgta gatggacaaa ccaaagaaga aattttagaa
     6541 ttagaaagac atcgattagc ccgtgagctg catgattcag tttcgcaaca attgtttgca
     6601 gcaatgatga tgatgtcggc attgacggag caagcagaaa aaagcgagac accagaaatg
     6661 tttcgcaagc agttgaaaat ggtagcagag atcatcaacg cttcccagtc tgagatgcgt
     6721 gcgctgcttc ttcatctacg tccagtcaat ttagaagaga aaagtttaaa gcaaggtatc
     6781 gagcagttat tgaaggaatt gcaaaataaa atccagattt cgctgaaatg ggatgtagaa
     6841 gatgtaaaac tatctagttc cattgaggat cacttgttcc gaatcgttca agaattgtta
     6901 tcaaatacat taagacatgc taaagccaat gaattagagg tatatttgca caaaatagac
     6961 aataatcttt tgttacgtat tattgacgac ggaacagggt ttaatatgaa tgaaacgaaa
     7021 acgggaagtt atggattgaa caatatcaaa gaacgagtag ctggtattgg tggaacagta
     7081 aaaatcatta gttttaaagg tcaaggtaca agtgtagaaa tcaaggtccc tttgatgaag
     7141 gaggcataga taaggatgat aaaagtttta ttagtagatg accatgaaat ggtgcgctta
     7201 ggcgtctctt tttatttatc tattcaagaa gacattgaag taattggaga agctgaaaat
     7261 ggacgacaag gctatgagaa ggcgatgaca cttcgaccgg acgtcatttt aatggactta
     7321 gtcatggaag aaatggatgg tatcgaatca acaaaagcaa tcttaaaaga ttggccagaa
     7381 gctaaaatca ttatcgtaac cagttttatt gatgacgaaa aagtttatcc tgccattgaa
     7441 gcaggtgcag cagggtattt gttgaagacc tctaccgcac atgaaattgc tgatgctata
     7501 agggcaacgc aacgtggcga gcgagtatta gaaccagaag tgacaacaaa aatgatggaa
     7561 aaaatgagtc ggcgaaatga gcctgtatta catgaagaac taacgaatcg ggaaaatgaa
     7621 attttaatgc tgatttctga aggaaaaagt aatcaggaaa tagcggacga attgtttatt
     7681 acactgaaaa cagtaaaaac acatgtttcc aatatattgg ctaagctaga agtggaagac
     7741 cgtacacaag ccgctatcta tgcattcaaa catggtttgg tgaaataaaa acgatgataa
     7801 agaggataat caaaagctga gaaaataact attatttttc ttggcttttt tacaataatg
     7861 atgcttgctt ttgtttttgt aaaggctttg ttatactgag aaaagaagat actaaaggag
     7921 gaaaacggtg aaacaaaatt ttgcaattgt aggtcttgga cgatttggcg gaagtatctg
     7981 ccgaacactg atcgaagctg gtcaagaagt actggctatt gatagtaatg aagatcgggt
     8041 caatgaatat atgaatatag ccactcatgc tgttgtggca aatgcacagg atgaaatgac
     8101 acttcgatca ttaggcataa gaaatttcga tcatgtaatt gtcgctattg gagaagatat
     8161 tcaagccagt atcttagtta ctctgatggt aaaggaaatg ggcgtaccaa atattttagc
     8221 aaaagcccaa aatgagtatc atgccagagt acttgaaaag atcggagctg atcgcgtcgt
     8281 ccatcccgag cgagacatgg gaataaggat tgcgcataat ttagtgtcaa agaatatttt
     8341 agattaccta gagttgtcag ataaatattc tttagcagaa atccgagtct ccaatcctaa
     8401 atttttcaac aaaacattag ctgaattaaa tttcaggcaa cgttttgact taacagtagt
     8461 cgccatacga agagtagatc aaacggttat cgcttctcct gcagcagatg aatatgttcg
     8521 tgaaaatgat aatctactgg ttattggaga gacaggcgat gtggatattc tagacgataa
     8581 gatgaatcaa tagaaagaaa agagaaagta ggttgttggg atgaaattaa cggtaacgcc
     8641 aaaagcacaa aagtggtttg actcagaaat tgatctgcca gaaacttacg gaatacgttt
     8701 ttttggaaaa gtctacggca aaacagaggt tcatgatggt ttttcgattg gaatgtcagt
     8761 tgaacagcca gaacatcctg taaagaaagt ggaaattgat gggacacttt tttttatcga
     8821 ggaagcagat gaatggttct ttaaaggata tgatttactt gttgattatg atcccaacct
     8881 ggaggagcca acctatcact ttaaaaaaca ataaaaaaag agagggtgac acaatttttg
     8941 tcaccttctc ttttttcttt tgaaaatatt gttttcagct attaatatcc tgcagacaat
     9001 ttt
//
LOCUS       DAFENC010000075         8534 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.079, whole genome shotgun sequence.
ACCESSION   DAFENC010000075
VERSION     DAFENC010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.079"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..516)
                     /locus_tag="LP493_002623"
     CDS             complement(<1..516)
                     /locus_tag="LP493_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134729.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPK"
     gene            complement(526..1686)
                     /locus_tag="LP493_002624"
     CDS             complement(526..1686)
                     /locus_tag="LP493_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBL2134730.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            complement(1686..2372)
                     /locus_tag="LP493_002625"
     CDS             complement(1686..2372)
                     /locus_tag="LP493_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HBL2134731.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            complement(2335..3513)
                     /locus_tag="LP493_002626"
     CDS             complement(2335..3513)
                     /locus_tag="LP493_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBL2134732.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            complement(3533..5227)
                     /locus_tag="LP493_002627"
     CDS             complement(3533..5227)
                     /locus_tag="LP493_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBL2134733.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            complement(5205..5519)
                     /locus_tag="LP493_002628"
     CDS             complement(5205..5519)
                     /locus_tag="LP493_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HBL2134734.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            complement(5622..5903)
                     /locus_tag="LP493_002629"
     CDS             complement(5622..5903)
                     /locus_tag="LP493_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134735.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            complement(5908..6252)
                     /locus_tag="LP493_002630"
     CDS             complement(5908..6252)
                     /locus_tag="LP493_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBL2134736.1"
                     /translation="MTEEFYRWLLQLIREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            complement(6278..6445)
                     /locus_tag="LP493_002631"
     CDS             complement(6278..6445)
                     /locus_tag="LP493_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134737.1"
                     /translation="MYRPQYLEQKHEVITVQNGNGEIVRKYRRPIKSDTYKRKESNEV
                     IPLYGKRIAKY"
     gene            complement(6512..7159)
                     /locus_tag="LP493_002632"
     CDS             complement(6512..7159)
                     /locus_tag="LP493_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134738.1"
                     /translation="MVGVVKFLGFTFDGYGTLGEWVGIILIVITIQQTSKYYWYSNSS
                     KIVSRITEGITKKDITVVGKYGFTITLLNEGKSETAIKFCGIIGKYNIFQRFIRKHWY
                     KYIYKYPVVKKLIEKYVDHEISYLNPTDLINQEFQNIGYLEKGLKIPIVNESLVTAMV
                     ANIKNSKKLEKRYKKCKKLKFSFLFLEYNGKEYYQDIYVLRGSNLYKDIKNKISV"
     gene            7369..7560
                     /locus_tag="LP493_002633"
     CDS             7369..7560
                     /locus_tag="LP493_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegP family protein"
                     /protein_id="HBL2134739.1"
                     /translation="MVKNLYFVIREATNGQYYFVIKSNNNEVVATSETYLTKYSAEQT
                     INSIKNGITKDSQVIDMTK"
     gene            complement(7553..7894)
                     /locus_tag="LP493_002634"
     CDS             complement(7553..7894)
                     /locus_tag="LP493_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134740.1"
                     /translation="MEVEQIKYQGMDRERLIDIIEQQRLELIQKEAVCKEYKKHLEQV
                     IEYHSVEKYRSVVQKNRATSPDSRQDVSISIKTPVFNSVKSEKLESISTALVEKAAEM
                     NSLANEVSRLI"
     gene            complement(7918..8154)
                     /locus_tag="LP493_002635"
     CDS             complement(7918..8154)
                     /locus_tag="LP493_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134741.1"
                     /translation="MYWRVYKMKIASEKIDQLTILVNQRIEDIIKEFEGEKIKNIKLT
                     LMDHKFELNSTKRKIVELIEEEIALQINEQQLAN"
     gene            complement(8429..>8534)
                     /locus_tag="LP493_002636"
     CDS             complement(8429..>8534)
                     /locus_tag="LP493_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HBL2134742.1"
                     /translation="VTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
BASE COUNT         2520 a         1735 c         1194 g         3085 t
ORIGIN      
        1 tttagggcgg ttaataaccc actgtgcgcc tcctgaatta gtgtttatag tttccaaaga
       61 ttctactgta acatttacaa tgtttgccat atcttttaga atattttctc cgttttcaca
      121 gcttctaata taatcaagac ttagataact acagcagtcg ctacaatacc aaacatcatc
      181 tttagaaggc aatttgcgca aattaattct tttattgaaa atgacatccg aatcgatata
      241 gaaatatcgg tcgtcctcac gcgaatgatc ttcttctaaa tatttccacc ataaatatgg
      301 tttaatcgaa ggaatatact ctttgtcgtc ccgcagatca tcgtacacat gaacttcaac
      361 accatattcc ttctcaaaaa aaataggaat ctgatcatcg tgtctgctga aaagcaatac
      421 gatatctttg attcctagtt tcttcagatt agttaaacaa acttcaagct cccatttaaa
      481 ccgattgatt gccggctgac aaagaatata cttcattctg atcacctacg cttgtgttgt
      541 agttgttgtg gttgttggtt ttgtagttgt agtagtagtt cccaaagcgc taatatctaa
      601 tacaatgaaa ctatcgttac gtttaggttg accgtttgca tattgtttag ctagataaat
      661 gcgttcgtct tcaacaaaat ggtattcatc tgaagcttca atttttagtg tagatcctac
      721 acccatgaag taatctgagg ctaccccaat aactgctttt ccttctggca cagccgttga
      781 ctgcaaatct gaaactggta ctggcaatac ttgtacgtat tctccattag cagttagtac
      841 agtcttagct gggaatactt tagaccagta atcagttgga ttcacaatta ggaccacatc
      901 agaaggattc acattacgat aaatcggatc attcacacct tcgatattga attttgatag
      961 tcgcgccatc aaaccgccca tagttacagc atctaaagct gtaataggtt ctgctttttt
     1021 ttcagcatat tctccgctag tttgtttgct catgtcacgc atcattccga ctggcatatc
     1081 tttaccagta ccatcaacaa ttgcttgttc taatgcaatt ctcaatgatt ctactaaaac
     1141 agtacggaca taacgatcta accatactgg acctaaatca agcattgcct tacatacagg
     1201 aatataacct gatagcttga actgcttcat gttaattaca tcaaagccat tatctaaaac
     1261 ttttttaaca gcttcgcaaa gtttacccca ccatgctgga ttgactccac gtgacacaat
     1321 ccattctgtt acaccagttg tgttaacaaa agtaattttt tgcaatagtg gatgagattg
     1381 ttctaaatct tcaaatacac gttcaaatac agtagctggc actaattctt cgacccctgc
     1441 aaaaccttcg tttttcacta cttcgttata gaattttgtt tcttgtgtag ttaatacacg
     1501 ctgaccacgg ttcattaata ctaattgatc ttgatttttt gctgttgctt cttctaaaat
     1561 tttatcctga atttccttag ataagcttac catagctgcg ctaaaagatt cttcgttacc
     1621 atctttaaaa gctttcatca attggtcgct tgcagctgtt acacctttta aatttttaac
     1681 tgtcattatt ttacatctcc ttgtccaaat gttttattta atgctgctgt aaatgcagca
     1741 attttttctg ctcttttttc tttaacgtca ttcaaaattt cttcaacgct ttgttctttt
     1801 ttagcttcag tacctgagct attttctgca tcgataattt catcgaccaa tccataactc
     1861 aaagctgttt ctgcatccat aaacgattct ttttcaagaa gttcttgcaa tgcttcatct
     1921 gtgccattga atcgtgtttt atatgaagcc tttaccgatt tatcaattga ttccagttgg
     1981 tcagcaatcg tacggaagtc atcgacattt ccttctccgt atgtggaagc gcggtgaatc
     2041 atcaattgtg cattgttgta gatttttata gtatcgccag ccattgcgat aattgaagca
     2101 gcactagcgg ctaagccgtt aatcacaacg ttaacttttg ctttatttga cttaagtaag
     2161 ttcccaatag caatcccttg aaatacgtct ccaccgtttg aattaattac tacttcaatt
     2221 tcttcttgat cacctagact atccaaaata tttttgattc ccttgtcagt attcccttca
     2281 aagaaccaac tagaaccaat aaatccctga ataaaaattt gcggtactgc gccttcattc
     2341 tttactgcta gaaatgtttt cattgtcgtc attcgcctca cctcctttcg atacttgttg
     2401 attgttttta gttataaata tttcatctgc catcgcctta tcagagcgat catttccaac
     2461 gcgctctctt ccttcgttga ttgtaaatac tccatttcta atgcctacat caatagcgtc
     2521 aaccaaatct ttgaagctag taatcttgat catagttgta tccacacgta caaaattccc
     2581 tgacaagtat tcttctactt catagagact agcgttaaac gcatcctgaa taagttcagc
     2641 aatcggtatg atttcgaaca ttaaaaaagc gtccacttga tccgataacc cactcatgtc
     2701 tccctttagt aggtttttcg gaacgtgaaa cgctgctgct gtcatctcaa agatgtcgtc
     2761 tattaagttt tttatatctc ttgaattgct ttggaagttt ccgctgaaat cttctaatgt
     2821 gtactcattt tgtaattgaa ataccgcacc tgcattatca gcttccataa aagccttaaa
     2881 ttgtgatgtc atcattttat tgatttgatc ttgtgttgta ttgtcttgcg gtcggaataa
     2941 attccctttc agtacgtatc tacgagcgtt agagcgcttg taaacattca tggcactaga
     3001 aatgagtttc ccatacgctt gataatacgc atcgactagt tgcctaattt gttgatctgc
     3061 gtattttata tagataacat cactttctag aaattctcta tcaaggacta tgttgttaat
     3121 ttgcacttga gaaaacacat catctttcaa tgcatattct gtgacatccc aactatccgc
     3181 aataaatatt tcgctagaat tattagacgg agaaacgatc aatacttcat tgtagaatat
     3241 taatctcctg atcagttttt ttctaaattc tgttgcatta tttttcttat taggagctac
     3301 attcagccta tagtaaagat cattcttttt attttttcca tcttcatatg acttgaattc
     3361 cgctttactc atcgcatttg caatcaaatc aatacaagtt tcaatcgcaa attttcgata
     3421 cacaaaatca acttgcaatt tacaaaagta ttcttctaaa ggaaccgttg ctttttttgt
     3481 gaagtatcct accgcctttt gaaaaatccc cactttctca cctcctttca agttagaata
     3541 ctagaggagt aaatccagtt cctgtatttt ctactgagct atttgtgact gttacaggag
     3601 cagaatcata aatatcatct aaaaaattca aaccatgaag gaatgaaaaa aagccatccg
     3661 tttttctagt ttcaggttct attttttcat agcgtatatt tccattagaa atatgctctt
     3721 catatacatt catgcaatac caacgcataa tcgcatcgtc accaaaaaat aaacgttgat
     3781 taataaaaag gtcatcaacc agatctttta acataccatg tgtaacagat ccgcttcgaa
     3841 caatttccac agtaaaacct gcttcttcta aagcgggctt caatattttt gcacggtaca
     3901 tatccatagc gattttttta atataatatt tattactcat ttcaagaaac caacctacaa
     3961 tataatcagc ttctatattt tttccatgaa cgatctgtga ttttccttga tctatagaaa
     4021 tatctataac ctctcgtttg atgttttgta atcgaagggc tgattcgtgg ataaaagtat
     4081 gttgtgtaaa ataaacatct ttatcgtatt ttcctagcaa cccaacgctg gcaaaatctc
     4141 gtctatcagc aaaatcgact gttcctatca cttcatccat tttttcagga aattcttttt
     4201 ctttcgtatg cagaacatca tcatatgaag caacagcaaa tcgtgtatct tccataggtc
     4261 tgttcattcg tttggtcatg aacgtaagtc ttaaaccagc attacgttgc atttgagagt
     4321 attcttgaaa cattttccgt tttaaatctg cattgtaatt aatagttgga caagcttttt
     4381 cccacatgtc gggatcatca acttcattat cgttatccaa gcgacaaata aatggaaaca
     4441 aactagaaaa ttctgctcca tccttgtcaa ttccaagttc tccagaaaga atcatttttg
     4501 attcttctat aatgtcatca agcggaccac cacgaacatg accattagtt gtatcataaa
     4561 attctctata atctcgaatt ttaccaccac cagaagtagc cacatttatc attgaataat
     4621 cttcattttc gtgaatttca tcaaagcggt ttgcacctgg tcgcttccca tcttttgttc
     4681 tagcatttgc cgtgttataa cgaagtttgc tgtttgtagc gatattttga ataacttcct
     4741 tcgtagcttt aaatactttt ttatctaaat caggatgatc tttaattact ttaaatacat
     4801 catcaaaact agtctttgct tggctttcat tattggcata gatatcaata tcataatttt
     4861 taataccgtg tttagcggtt agtagaaaga agttgttcca agaagcaaaa ccagttttac
     4921 cattaccacg tcccattaat gaaagatatc tattgaacac tagtgtttta tcttttttcc
     4981 atcgaacacc ataaataaaa cattgtagaa atttttccca cggaattaat tcgaatggaa
     5041 agtattgtgc tggtatattg attgaatcct ctaccatctg cttatcgaag taaatatctt
     5101 ctctagtaaa gactctttct tctagataat tttttagcaa taattgctct ttgcatacct
     5161 tgatagtgcc ttcttctata gctttgaacc aattttcaat atgcttataa ctcaggaatt
     5221 gattcatttg cttcacctac caattcagga gtaatggcaa gtttatccaa catcaatccc
     5281 atttgtttgt tgacagaaac aagcaacgct actgattcat tctttttacc attctccagt
     5341 ctaatgccgt tctcggatat atcttcttcc agtgatatcg ccgtttccca taaactgata
     5401 taacgatcaa cattatctaa gaatggctca atatttgttt tctgactttc caattggctt
     5461 attaaagagc ggcgtaattt ttctctgtag cgattttgag acaattcgtt tttaaacatt
     5521 ttagccctcc tttcatgata aagttcgaaa aaatctcttt tcctgacagc cccctccgtt
     5581 tcatcacccc caaaaaattt gcgatttatt ttaagggggg gttatctcac catcggaatg
     5641 aaagcttcag cgaagtcaat gtaataatta atctcttcaa tactatatcc aaaaacattt
     5701 tttattcttt cgacgttatt atctttattc aacgcttctc ttacttgatt cactttgtat
     5761 ttactacaac agttatctga taacagatcc ctaataccta catagcgaac gtatatcaaa
     5821 cgtttaatta atccctgagt ataagatgaa tactcttcaa tcttttctgt atcatactct
     5881 ctgccattgt cattgatgat catgcactta ccacctttca cttgcatcga agttagcgaa
     5941 gctttctatc ttcttctctt gtttatctaa cgctgtaaga tatctgccat gaacttcatt
     6001 atgatgttca acacataaac aaataagatt atctaaatct aaagctaagt caggtctatc
     6061 cttgacttcc tttatatgat gaacgttctc tactctatga tacttaccta gtcttctaca
     6121 ctcttggcat tcatagtgat ctcgtttcat cgctttctct ctaagcctgc gccatttagg
     6181 agactgatag aacttaacca aacgatcttc tcttatcaac tgtaataacc atctatagaa
     6241 ttcctcggtc atgtcccatc tcctttcgca atcttattta atacttagct attcttttgc
     6301 catacaatgg aataacttca ttgctttcct tccgtttata tgtatcgctc tttattggtc
     6361 ttctatactt tcgtactatc tcaccgttac cgttttgcac agtgattact tcatgcttct
     6421 gttctaagta ttgtggtcta tacatcgtcg tgcctccttt acgcaaaata aaaagaccac
     6481 tcaaagagtg atctacgaat tttaaaaaat ctcatactga aatcttattt ttaatgtctt
     6541 tatataagtt cgagcctcgc aaaacataaa tatcttgata atattctttg ccattatatt
     6601 ctaagaataa aaaggaaaat ttcaattttt tacatttttt atatctcttt tctaatttct
     6661 tgctgttctt tatgttagct accattgcag taactaaact ttcatttaca attggtattt
     6721 ttagaccttt ttctaagtat ccaatattct ggaattcttg attaataagg tctgttggat
     6781 tgagataaga tatttcgtgg tccacatatt tttcaataag ctttttaact acagggtatt
     6841 tgtaaatata tttgtaccaa tgctttctga taaaacgttg gaaaatgtta tatttaccta
     6901 taatcccgca aaactttatt gcggtttcag atttcccttc atttaataaa gttatagtaa
     6961 acccatattt accgacgaca gtaatatctt ttttggttat tccttcagtt attcttgata
     7021 caattttaga actattagaa taccagtagt actttgatgt ttgttgaatt gtaatcacta
     7081 tcaaaataat acctacccat tcgcctaacg taccatatcc atcaaatgta aacccaagaa
     7141 atttaactac gcccaccatt ttctatcacc tcagaaataa tattatcaaa taatcttaga
     7201 taactaaaca ggggacttgt aaatttcaga taattactca ttgacttttc ccattcatcc
     7261 tttattgcgt ctaccctttc cgccacagcg acaaattgat attgtgaaat tttatacata
     7321 gcttataatt ttaattatca gcgagtggtc cgctgaaata aattataggt ggtgaaaaat
     7381 ttgtactttg ttataagaga agcaactaat ggccaatatt acttcgttat taagtccaat
     7441 aacaatgaag tagtagcaac tagcgaaaca tacttgacta aatattccgc tgaacaaacc
     7501 attaattcta taaaaaacgg aatcaccaaa gactctcaag ttatcgatat gactaaataa
     7561 gacgactaac ttcatttgct agggagttca tttcagctgc tttttctacc aaagcagttg
     7621 agatactttc tagcttttct gatttaacag aattaaatac tggcgtcttg atactaatcg
     7681 atacatcttg acgagaatca ggactcgttg ctctattttt ttgcaccact gatctgtact
     7741 tttctactga atgatactca attacttgtt ccaaatgttt tttgtactct ttacatacag
     7801 cttctttttg gatcaattct aaacgttgtt gctcaataat atcaatcaac cgttcccgat
     7861 ccataccttg atactttatt tgttcgactt ccattcattt cccctccaat acataaatta
     7921 attagctaat tgttgctcat tgatctggag agctatttct tcttctataa gctcaacgat
     7981 cttccttttt gtcgaattta attcgaactt atgatccatt aaagtaagct ttatgttctt
     8041 aatcttttca ccttcgaatt ctttgataat atcttcgatt ctttggttta ctaaaattgt
     8101 tagttgatca attttttcgg aagcgatctt cattttatat accctccaat acataaatta
     8161 atagacagca acggatgata gataataaga acaatttaga aggagttgaa attcacatcc
     8221 ttattcttaa tatttccgct gctgcctatc gaagcttaat taaacgatga gggagatttc
     8281 ctcccttaca ttttattttg tcgatcctgt ttcctaatct ttcgacacta tcataataca
     8341 acgttgaata ggtaagtgat tggtataaaa aaggtataaa atggaaacca aattggtaat
     8401 aaaagggtat aaaaagtgta aaaactggct acttgaaagc aaccagttct aacgatgaag
     8461 caaattggat gataattctg tttgattcta ctttaaccga ttcttcgcta gtattattcc
     8521 tttgagcagt taca
//
LOCUS       DAFENC010000076         8494 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.080, whole genome shotgun sequence.
ACCESSION   DAFENC010000076
VERSION     DAFENC010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.080"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..173)
                     /locus_tag="LP493_002637"
     CDS             complement(<1..173)
                     /locus_tag="LP493_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006735101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2134743.1"
                     /translation="MATKIADELENHVLETGMQKITTHASITAKPFFEKRGYKVINEQ
                     TVELRGQLFTNFL"
     gene            complement(593..1714)
                     /locus_tag="LP493_002638"
     CDS             complement(593..1714)
                     /locus_tag="LP493_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HBL2134744.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVVDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYRPG"
     gene            2042..3451
                     /gene="istA"
                     /locus_tag="LP493_002639"
     CDS             2042..3451
                     /gene="istA"
                     /locus_tag="LP493_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HBL2134745.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3448..4176
                     /gene="istB"
                     /locus_tag="LP493_002640"
     CDS             3448..4176
                     /gene="istB"
                     /locus_tag="LP493_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HBL2134746.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(4304..5215)
                     /locus_tag="LP493_002641"
     CDS             complement(4304..5215)
                     /locus_tag="LP493_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL2134747.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5232..6239)
                     /locus_tag="LP493_002642"
     CDS             complement(5232..6239)
                     /locus_tag="LP493_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBL2134748.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSSPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6236..8365)
                     /locus_tag="LP493_002643"
     CDS             complement(6236..8365)
                     /locus_tag="LP493_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBL2134749.1"
                     /translation="MKKKLFRIVGIVFISIVTLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8370..>8494)
                     /locus_tag="LP493_002644"
     CDS             complement(8370..>8494)
                     /locus_tag="LP493_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL2134750.1"
                     /translation="NGQCLMQDLYGRVGVVQVHPVFEELFHAFDTRPPVQERME"
BASE COUNT         2599 a         1728 c         1486 g         2681 t
ORIGIN      
        1 attaaaaagt tagtaaataa ttgccctcta agttccacgg tctgttcatt aataacttta
       61 tatcctcgtt tttcaaaaaa tggctttgcg gtaatggaag cgtgggtagt gattttttgc
      121 ataccagttt ctaaaacatg gttttccaat tcatctgcaa ttttagtcgc aatacctttt
      181 ccttgatggc tatgtttttg tcacaacttc agtattcctg taacaatacg gatttcagta
      241 tacaacaaca gcttttgaaa agatacttgc aaaaggatta agatatctat gacctgctat
      301 gctcactgat gttgaaaaga atgttttatt aggattgagg taagcaagat agtgaatatg
      361 tccggaaagc ctgtaaaata aggcttttcg gacatatgtg aagttataaa aagatagcga
      421 aaaatctatt tagtatcact aatgttgcga acatatcgtc agaatagtct gacatttatt
      481 tcttgctaaa aatttcaaaa aagtcaagtg ctgacgcagc ggatgactat tttccagaaa
      541 attttagtat gtattcaaaa atcaaacgtg acaacagcta ttaactacat cctcatccag
      601 gtctgtaacg tttgaaccac tcttctgcgg gctcaaacat taagtaatgg aaggtacgtt
      661 tcaattgaaa cagcgtcgct gtcgtattca actcaatttt tatcacataa gtgagaagcg
      721 ttgcgattaa ggtgaggatg acttgattta tcgccccttg ttcactatgt gaatatagtc
      781 gtttaatggt cagattttgt tttaagtgtt tgaacaacaa ttcaatctgc caacgggctt
      841 gatacatgtc ggccacttcg tttggcgata catcaaagag attggtcacc attcgcagga
      901 ttttttgtcc cttggtaaga accgttacca acctaaaacg ctctgtcaca tggttgacac
      961 cgccgacaag aatcacttgt tggtcactga ttatcgtccc atcacgggtt gttgtatctg
     1021 ctacttcaat ttgatccaag atggtaattt ttgtattaga ttttgtccgt gtaacgaaga
     1081 aatagccgtc acgatttagt ttgtctaaca acttgtaatc aaagtagccg cgatccacca
     1141 catacgttgc ttgcgtttta tcaacaagaa cttcaaggtg attacggtca tgctcactcg
     1201 catttgtcat cgtaaaactt tcaggatact gattggtttt atcaagataa cagagattca
     1261 aatgtagctt gatgccagac tttgttttcc gaaacttggc ccatggaaac catgctttgt
     1321 tcaacggaat agtcgttgaa tcaatcaatt gtagactggt tgtttttgag cttggctgct
     1381 gagcagaaat tctggcgact aattgcgtaa aaatttccat caatacttct tgcttgattt
     1441 ctggcgctct acgagataac gagctgtaac acagggaatc aatgccaagt tccttgcaga
     1501 ggcgctgatc taaaaaggcg cgatcaatct cgcgatagct tggcaattct tcataaaccg
     1561 catgaagtaa cactttaagc gtcgtttgga agtctagttt tttactgtag aaatcaaagt
     1621 cgctaattaa gctttgagag ttttctgata aaccagaaaa atttattgca gaaaaccatt
     1681 tttgaaatga ggtttttacg ttatacttat ccatgcgtga gtccttttta ttggtcttgg
     1741 ataagtcatc cgagaatagt ataaaggact tttttgcgtt tggatagctt tgtattaggc
     1801 ttttgatggg ttaaaaagtc tttgcaacac tagtaattta gtatttatgt ataaattgaa
     1861 agatatttta ccaccactta gtcttcttaa aagtgatcca acattttgtt tgtggcagaa
     1921 tttaactaca cactaatgca gccgaaagta cacaactatg cagcagtttg actgcgaact
     1981 ggtttccttc catcataagt ttgaatgact tagtgatgga ggtacagaaa ggttgttaac
     2041 tttggatgat attaaaacaa taaaacattt gagaaataat cgtgatcagt caattgatca
     2101 gataagaaaa gcaatgaata tcaattggcg aacagcgaaa aaatacgccg atagtgatca
     2161 actattcatt acagatccca ctcgaaaaaa caaatccatg atggatgatg gttggggaga
     2221 aatcatcggt agttggctag aagaagacct acgtttacgc agaaaacttc gtagaacggc
     2281 caaagctatc catgaacaat tgaaaccttt gggtttccct ggctcctatc gaacagtttg
     2341 tgtatacatt tctcaatgga aaaagcagcg ttacgacgaa acgaattacc aagctgtcga
     2401 tcgtcttgat catccgatcg gagaagcaca ggtcgatttt ggaacaatgg aagttatgca
     2461 tgaagatcac atgaaagata tacaacttct tatcatgtca tttccctata gtaatgcgac
     2521 gtccgcaagt gccatgccag ctcaaaacca agagtgtttc ctggaagcat taaaacaact
     2581 atttaatcaa tgcggcggcg ttccaaaaac gatcagaata gataacttaa ctccagcggt
     2641 gaaaaaaaca aaatcaaaat ttgaagaagc acaactaacc gatgaattct tacgtttcac
     2701 cattcattat ggttgtgatg ttcaagtctg taacccacgt agtgggcatg aaaaaggaca
     2761 tgtcgaaaat aaagtgggtt atgtccgata caatttcttc tcgacttcgc caatcatgga
     2821 ctcttttgag tccctaaata agcaacttga agaacaatta aaagcagatc gaaaaaggac
     2881 gcattattca aaacatcaat taatcgaaga tttgtggaag aaagaaaata aagcgttaca
     2941 ttctcttcca caagaggatt acccaatttt taaagaagtg gaagctaaac taaatcgtta
     3001 tcacgaaatg aaattggatc aaacggttat tcatattcct aaagcatatg gctattctca
     3061 attgactgtt gttttgactt ggaataaatt caaagttctt acgcctcatg gagaaatatt
     3121 aatgaacgaa tatcgcccct atatgaacaa aaaaagattg atcccatgga gtgacatcat
     3181 gaaacaatgg agtaataaat tgaatgtcgt tagttattcg aggtattgga agtacttgcc
     3241 tgcacgcctt caaaattatc tagcgattga taataatcac ctgaaataca gacggataaa
     3301 acaattacta agtttattag cgacctacga tatccaacaa attaatgaac aattttacga
     3361 attagtcgtt caagaagacg ccccctctga ctttgatgtg aattggtcaa actatgatgc
     3421 attaacaaaa acaggaggtg tgcaaaaatg attggacaga cgttagaaga ttattgtaaa
     3481 aagcttcgat taagccatat catcacgaac ataccaagag cttctttcga agctccagaa
     3541 caatttatta ccgatttatt ccgtttagaa ctggagacca gacagcagat caaattagaa
     3601 cggatggaaa aattagccaa atttcctgta ccaaaatcgc taaagaacta tgaatggcac
     3661 gaagatattt ttctaccatc tcatctagat aaggagaccc ttgtctctct tgattttcta
     3721 aaaaggcaag aaaacattgt ttgtgttggc tctcctggta cagggaaaac acatctagcg
     3781 atcgcattag ggagaaaagc ctgtagtgaa ggtgtttcaa ccaaattttt ccgagttaac
     3841 aatctcgtag agcaattaga gaatgcatta aaaaaacaac agctagccag tttcaagaag
     3901 cgattcgaaa caacagaatt aattattctt gatgaaatgg ggtacttacc attgacaaaa
     3961 gaaggagctg aacttctctt ccaactgatt tcagattggt atgagcaaaa gagcattatt
     4021 attacctcta atttagaatt cagtcaatgg aatcgagtgt ttatggattc tcgattaaca
     4081 gctgctctcg ttgatcggct aatccatcac gctcacatta tcagcttcaa aggcgaaagt
     4141 ttcagattga aaaattcatt atctaaatca tattgaagga aaaaactagt tgcagcaaaa
     4201 ctctgcactt tcggctgcat ttttttgtaa aaagctattg cacaacacaa acatttgaac
     4261 gacgtaattc caaatgttgg attgctttta gataatcttt tatttattca caattgctaa
     4321 tagtccaatt ttcatttttg tatagtttta atctatactg aaaaacactt gttgttttgg
     4381 acaactcatc aagatactca acaccaacaa tcacttgaat cgctttaccc ttttgtttgt
     4441 aaataggatt cactaattcc acaaatttca aattagtatt aattggttgc atcgcgtctt
     4501 tttcaacata atgctctagt tctttttctg aggctgctgg ataaagcctg aaaaacgtct
     4561 ctaaaaactc ggtgatttct tccgttgtct ttgaatcaat ttttgaatca ctttttactt
     4621 gtcttacttt atgttttgcc ttttctggct taccaatcat agtgggtaaa ctcgttacaa
     4681 tatgattgcc tttttcatct tcaaagatca tcagacgata tgcagaagaa attgattgtg
     4741 tctttttccc ttctgtaatc ttttgatcta ccacaaatga aacgacaaat tcttccgagt
     4801 gtttttcaac atctagaatt tttactgata caacctcgga actagtggga atatccgctc
     4861 gaaccatatc ttggctcaaa gcgagccctt cttctgtaag gtactgctca agattagtca
     4921 ttctcttttc aattacctcc ttgttattct tccatgaaaa atattctttc acaaaatcta
     4981 cagtaaaatt ttctactcca gaggtattca ctattttctc tttcacgacc actttctcat
     5041 gagttgtatg ctgatcaatg gccgtgaagt ttttgtagat tccaaaagca aggctacaag
     5101 acaataaaag ccaaagggca agcaccattt ttcgatgctt gcccacggat actactcgtt
     5161 ctttcttctt ttttggaatc ttttccttgt tacttcgctc aatttttatc ttcattttcc
     5221 attcctcttt tctattgttt ataccgacca gcaccaataa tgtgctgttg ccaatagcta
     5281 tcggtaagat tggtccaacc caccggatct cctgcatgaa acattctgtt ctctcctgca
     5341 taaatgccca catgagtcac ataagtaccg gcatcataag ttgaatgaaa gaaaatcaaa
     5401 tcgcctggtt tggcatcttt taagtcaata tgagtcatag catcatattg atcctgagcc
     5461 acccgaggga gtttcaaacc aactttggca taacaccatt gagttaaacc actacaatca
     5521 aacccagttc cgggacttga cccaccaaat acataagccg ttccttcata cttgaacgcc
     5581 tcgtcaaaaa ttccttggac tgttttatca tcaaactgtg ttgtagttag gtactgcttc
     5641 actaataagc aataaaacat attgccatag ttataccgcc acccactatt ttccttaatc
     5701 gcgatgggat tgggataatc gactttttga ccacccgatt tttcttttga aaaagattcg
     5761 gctaaagcaa aactatgctt ctttccgttt ttcgcgacat aatccaaata cccgtcacca
     5821 tagttataag cctgaatgat actatcttga tcgcatccta gttctttgga acacttaacc
     5881 aaagacgaaa aatagagaca cacttgtttg atggatgcct cggtacttaa tgaattcggt
     5941 gataaacctg ctgattcaga actttgcatg acatcttcca ttgtacctcc agattcgact
     6001 tgaataatcg ccaaaagaat cgaaacatac tctgttatat ctgattcttt ggcatacttt
     6061 tccaccattg aacggtgttt caaaactact tctgagacac tactacctcc aggagaagtt
     6121 ccagaactac cacttccctc accgtcctca ccaaacaaca aacccacaca catcaagatg
     6181 cccacaaaag agatggtcag gaaggttaac gaaataatac tcaatttttt taagttcatc
     6241 ttttctcacc tggctttggt tttgggcgag tgttcttttt tctttgtact tgttgattgg
     6301 ttcgctttgg aaaagtgaat ctctgtttca cttgttgaaa ggaattgttc ttgcttagtg
     6361 gctgagtgct tccgtttgga atgacttctt gactagaaag tttccgtttg atttcaggat
     6421 tcgaatgtac ttgtaccctt ggttttaaag acctattttc tggtagttca tttttctgtg
     6481 gttttatctc cttttttatc ggaacatttt cccttccttt ctcatgacga ttccatgctt
     6541 cgttcaatac tttgcgtttt tcatccattt ttgcgtctct tcgttgtcgt tgtttttctc
     6601 gcaactcccc tcgatttgct ttttcttcga aaggccctcg cttaaagtcc tctggtactt
     6661 ttttcgtctt ttccatgcct ttatgaaggc tgtatttcaa gttagttggt gcatcggtta
     6721 cttgattttt tgcttgtttc gctttgtcct tcacgatttc ttttgtatcg agtacttttc
     6781 caacttttct accaactaaa tttattcgtg attctttctt cgtgcccact ggttgttctt
     6841 gttttttcag atcagaattt agctcgttaa tgcttctcgc ggaatggttc tttctattgg
     6901 acactctatt gatttttgaa ctacctttcc cttttgtaga actggtagct agtttcccac
     6961 caactgctgc accgccacca aaagcaaaag ttcgacccac atttcgatta agctgtcgca
     7021 attttcgatt catcaacatt tgcggtttcc gcatgactcg ccttcccatt gactgactat
     7081 cattactttg aaggttaaac atgctcataa tgtcacctaa tttgaaatag ataccggcaa
     7141 aggtcacaat ttgtagaaaa gctaccataa agaagggata ggtggccgaa atattgaaaa
     7201 acatcgtgga gatactgaat gcagtcgtaa tgactaaggt aactcccgct cgcatcataa
     7261 tcgtattgaa caaacgaata atcgcccttt tgcccaaact ctcatacgtc ggcaacatcg
     7321 acaataagaa actaatgggc agaaacatcg caaagataat gaaaaggatt tgtgagaaca
     7381 acataatccc tgtcagaaga aacacaaaaa aggaaatccc aatattaaac aacactaaaa
     7441 agaccacggt tcctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattat
     7501 cttcaatctc tgctttgact gcttcttccc gatccttacc cttattttca tccggactca
     7561 cggataaaat cttattaacc cgaccctcgc caatttcttc tatattggaa tcatcgaatt
     7621 gtaatagtaa ccagggttgt tgaacttgaa tcgaaaataa actgtctcga atcaaatcca
     7681 cactatcttt tccctggctt tctgaattag gtacaacaat cttggttcca aggctaagag
     7741 ccgcttcact aacgtctgag ctaaagtcat tgatttttgt aatataggtg ggcgcatacg
     7801 caatgaaaga acccgagagt agaaaaatca tcacaaaatt aatgacggtt cggactgctt
     7861 tggtagtttc tcgttttaat aatccggtat acgccacata aactcctaga gctaaaatca
     7921 tcaataatag gaacccaaag tagaatcccg aagtctgtaa tccattttca gtgataccgg
     7981 ctaaagtttg gatattcttt ccaatacttt tagccgtatc cgaaatgaaa tccaacttgt
     8041 aagcttcttg aaccacatag cccgtggcgt ttgataaata cagacttact gtccaaataa
     8101 aattggtaat ggcataaaga ccatacatca cgcttttccc taagccatcc ccccaattcc
     8161 aaggtaacca atcccaagaa ctatccacaa agaaatccag ttgataattg ttcagagaat
     8221 atttggaata aaggtttccg gcttcaactg tatcatcaac cagacctgtc gcctcagcta
     8281 ccgtaccgac taaactcaat agaactgtca gagtgacgat gctaataaaa acgattccca
     8341 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac cggcggacga
     8401 gtgtcaaaag catggaagag ttcttcaaag actggatgaa cttgaaccac acctactcgc
     8461 ccatacaagt cttgcatcaa gcattgaccg tttt
//
LOCUS       DAFENC010000077         8424 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.081, whole genome shotgun sequence.
ACCESSION   DAFENC010000077
VERSION     DAFENC010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.081"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            471..2108
                     /locus_tag="LP493_002645"
     CDS             471..2108
                     /locus_tag="LP493_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134751.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSMGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(2253..2993)
                     /gene="truA"
                     /locus_tag="LP493_002646"
     CDS             complement(2253..2993)
                     /gene="truA"
                     /locus_tag="LP493_002646"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBL2134752.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(3184..3819)
                     /locus_tag="LP493_002647"
     CDS             complement(3184..3819)
                     /locus_tag="LP493_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HBL2134753.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(3966..5207)
                     /gene="sstT"
                     /locus_tag="LP493_002648"
     CDS             complement(3966..5207)
                     /gene="sstT"
                     /locus_tag="LP493_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HBL2134754.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            5405..6401
                     /locus_tag="LP493_002649"
                     /pseudo
     CDS             5405..6401
                     /locus_tag="LP493_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
     gene            6417..>8424
                     /locus_tag="LP493_002650"
     CDS             6417..>8424
                     /locus_tag="LP493_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBL2134755.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKILTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQK"
BASE COUNT         2785 a         1547 c         1293 g         2799 t
ORIGIN      
        1 aactaatcag aatcgtacaa atatttaata accaaatata tagaacataa cttaatatta
       61 agttatttga aattccataa aaaacgactg caggaattat tgtaagaaaa ggataaaaat
      121 agttcagtcc atctccataa ttgttaaatg ttgtatagtt gattggccct tcaaaaatag
      181 aagataaccc tttgattcgt gaaagatgaa aagataaatc acctgttgta taaatttctt
      241 gagcatttct cataaaattt actgaatata aagtactaag taagataaga actactaaaa
      301 gaaatgcttt tttacttatt ttcatagatt tgttgttctc cttttttaat tctattttca
      361 gtatactaga attgtctttt tttaataagt tttgcgttaa atttttcata gcactagtat
      421 gatatactag aaaagaatca atttttatta cttttaaata ggagaaaaaa atgaaaaaaa
      481 acaaaaacca aataatagat atcattttta tgttatttct aagttttgct tacgtcatcc
      541 ctctattcat gtctatggga atctatcata gtgtcaatca ggatacttac tttcatttat
      601 ctcgaatcat aggactagat aatgtatgga gttctccagt aaacttcaat aacttcgatc
      661 atcatggaac aatgatgaat attttttatc catggcttac tctttatcca gcttttttat
      721 tttataaaat gatgggaaat cttgttttaa gttataatat ctactatttt tttatcactt
      781 ttttaacaat ggtcgtttct tatttttcta tgaaacaaat aaaaaacaat cgttatattt
      841 cgctgttatt ttcgattatt tatacatttt ccgcctatcg tgccattgac atattccatc
      901 gtgcttcatt gggagaagct gtcgctttaa catttttgcc tttgatacta atggggtgtt
      961 acgaaattta tattagagat taccaaaaat ggtactggtt gtctattggc atgacgctag
     1021 tagtgtatac tcatttactt tctgtcgcta tggtttctgt atttattgga ggaacgttgt
     1081 ttctttcttt ttatttttgg gaccaaaaaa tcgctagact cttaagtctt ttaaaagcta
     1141 ccgtcctcac ctttttttta agtgcgggat tcttaattcc ttttattcaa caatctagag
     1201 cacaagaatt gaaagtccca ctgggaaaag aattaagtgg tatggctcct agtgatatgc
     1261 tgacacacat tttaaataat aactataaca actatactat tggattattc ttatttctcg
     1321 gattgattgg tgcttttatt tttataaaaa aattaactgc tgatgattta tttattttct
     1381 ttcttggtgt atttgttctt ttttgttcaa ccaatttatt tccttggcaa ctttttaacc
     1441 atacaccagt taagagtcta caatttgtct ggcggttaaa tggtttttct tctttattta
     1501 tagcctatac gatgagtata gtgatctatt atattttttc tactaaaaat aattcatgga
     1561 aaataatggt ctttacgttt cttgcactaa tattgcatct ctcaggagta agcaattcta
     1621 tccatgctaa caaagattca ttaacactta tagcacctga agacgctgtt gctatagctg
     1681 aaaattacaa tcatactgat tatgcaaaca aagagtcaat ctatcatcct gatatgatta
     1741 ataatgatca atatttacta ggtaaccagg aaataaatcc aacaactcat tttatgagta
     1801 acaaacttac aattgaatta gataattcga ataataaaaa tactgtcttg acgacaccta
     1861 tttatcgtta taaagggcaa gtggcttcta ttaatggcaa actagtacaa acaaaattat
     1921 ctaagtttgg cacaactgaa ttaactattc ctccaggtat aaataaagtc gttattactt
     1981 atcagtacac aaaactagca attgcttcaa gatatttatc tatcgttact ttgattttat
     2041 ttttacttta tcgatttact ttttctaaac aaaaacaacc gagaagagaa gtacaacatt
     2101 ctcactagat ttttatttaa gaaagacttt ttagctgtac acataaacag gctaaaaagt
     2161 ctttttttat atttctttaa tttgcttcat acattattta acatcgatat ttatactgtg
     2221 aaacatgcgt ttcatccatt atcaaagtat ttttatcgat aataaacttc atccaaaaac
     2281 agaccttgtg cagggacggt ttctcctgca tgttgccgca ctttgctttc aaatatttca
     2341 tcgattgttt ctatcggcat ggcacctgtg ccgatttcta gtaatgtccc catgataatc
     2401 cgcaccattt tatataagaa tccgtctccg acaaaagtaa aatgaagcat ttctcccttt
     2461 cgttcgatag ataattcatc aatcgtacgc actgtggatt tttttgattt tttcaatgca
     2521 gaaaaaccaa tgaaatcatg tgtacccact aatttttcgc aagctgcatt cagcttgtcc
     2581 atatccaact cttgagggaa ataaaagctg tggtttcgct caaatgctga aggaatcacg
     2641 ttgttccaaa cataatagct gtattttttg cccaccgcat tatatcttga atggaagcgc
     2701 tcaggcattt cttcgattct tttgatgaca atatcccgcg gaaggtaacg attcataaag
     2761 tcgatcattt ctgccagtcc aatttctgtg tttgttttaa aatttgctac ttgtcctcgc
     2821 gcatgggtgc cagcatctgt tcttcctgat ccaataattt ctatctcttc atttgtcatc
     2881 tgatgcaata ctttttcgat ttttccttga atggttttat cgtcatctcc aagtctttgc
     2941 catcctgaat atctttttcc gtcatattcg attgtcaact tgatgtttct catattttag
     3001 tggctcctct gtcttccatt tggtcttctc tctacctttt taagattgta gcacaaaata
     3061 tagctccttt cttctctaaa acagaagcta tacaagaaaa ctgtggaaat atatatttca
     3121 gaaaaacaaa aaacagccac cggatgaagt atccgctgac tgttcaattt gacggctcaa
     3181 gttttactgt ttgagatgca agatactcaa ccaggcaatg ggcacataat taaagaaaaa
     3241 actgattctt tggcaaaaac ctattttatt cagtaatggc caagaattta tagaaggaat
     3301 tcttgccagt ccataaatcg ccgcaaaaag caaactgatc acagacagtc caaggtataa
     3361 gtggcttacg tccatttgcc cattttttcg atagatcaag aaaagaagaa ctggaaacaa
     3421 taaaaaacca ctgtaaccta aacctgatcc gatattatgg acccatgtcg agacattcca
     3481 cgaagattca tgggtattga tactgaacaa acctgtaaag atacaatcac ctataccata
     3541 gaacgcgatg gctgctgtaa ctagggtagc taacacacga gatgtactta caaatgcagc
     3601 atacaatgca ggcaatgaca ggatgaaaaa gatccctgaa accacagacc aaataagaaa
     3661 cgcttttctt acaggactgg aaacctctcc aaatacactg atcacgctct tcatttgatc
     3721 taattcagga taatacaatc ctaatacgta cggagtcaaa aaatcactca gcacgcctaa
     3781 taataaaaag aaaaaaccaa atttacgtaa aaaatccatg atacgcctcc aataacaatt
     3841 acctatgctt ttaattgtta ttataagcga ctttatcttg atttaacaga aacctctatt
     3901 tacacgaaca tctatataac tcattaaaaa ctcgaatcat tttaaaaata ctaaatatct
     3961 aacgttcaac gttcacttaa tccatctaaa caatctttca atttgatttt ttccccactt
     4021 cttttacgcg cgcctagctc tcctattgca gtaaacaaca gatcacttga cgaatttaag
     4081 gcagtttcca ttgaatcctg gataacaccg ataataaatc caataccgac gatttgcatc
     4141 gcgacatcat tagagatacc aaacaaacta catgctaatg gaatcaataa cagtgaaccg
     4201 cccgcaacac ctgaagctcc acaagcagct aaagcagaca aaatacataa aaggactttc
     4261 aaaacaaaag gtgcttcaat ccctaaagaa tgtacagcag tcaacgtcat caaggaaatg
     4321 gtaatcgcgg caccgcccat attgatcgta gcacctaacg ggatcgatat ggaataagac
     4381 tcttttgtca atttcaatct ttcagccaac atcatgttta tcgggatatt tgcggcagaa
     4441 cttcgggtaa agaaagcggg aagtgcgctt tctttcaaac aaaagaaaat caatggatag
     4501 ggattttctt taataaacaa aaacgtgagg aatgggtaca caactaatgc gacaaacagc
     4561 atcgtaccga tcaaaacaag taaaagctgc agatactctg ccaatccagc tattccagtc
     4621 gtagcaattg attgataaac caatcctaaa atccctatcg gagcaaatgc aataatcact
     4681 tgtacgactt gtgacaacgc tatagatatc tgatccacca actcttttgt cgattctgaa
     4741 cgtgctcgaa aagctagtcc caacaataca gcccagaata agacgccaag gtaattcgca
     4801 tcaataagag attgaacagg attttgtgtg acattcgtca acatagtaga taaaacactt
     4861 tccaaacttt gcggtgcttt ttcagatact gtttcttgta aagtaatagg aacagtaaaa
     4921 attgaactta caataactgc tacaagtgca gaaagcaatg ttcccactaa atataagatc
     4981 aaaataggct tcacgaatgt cttattccca attttatgct tggcaattga cgccatcgtc
     5041 aagaaaaaaa ccagaatagg tgcgattgcc ttcaagcaac tgacaaacaa cgttcccaat
     5101 attgaaataa atgtccatgt ggggaaaaag ataccaaaca atattccgac taaaatacca
     5161 acaacaatac gttgaactaa cgacatatcc aaaaacttct ctaacaaatg accacccttt
     5221 cacaatttta acaatcattg tatcatttta tgcaaagaaa ctaaaggtat aattttctaa
     5281 aaattctaac aatacaaaca accatttctt gctaattttg tactttttct gtctacacgt
     5341 tgttttttga gatattctaa gttaggatgt tattaatggg caacttatca ggaaacgttt
     5401 tcttatgttt ttgtccaatt tttttgtgag gtgtttattc ttgaaaaaaa taaagaagga
     5461 gagttatggc ttcctgacaa tctttgtcgc ttgtataatg atggttttac agcgtatatt
     5521 gatttcagca gtcactattc ctacatatgc aacaaaccct ggtcgattct acatctatac
     5581 atttttacaa acttccgttg ttattggtgc aaatttgatc ccactttaca tgggttacca
     5641 atatcaaaaa atcgcccgtt taaaagtttt acattattta agtcgttttg cctttatatt
     5701 cctaatagcc acactagttt gcaatatctt ttttttacgt acaagctggc agcttgaata
     5761 ttcgtgatta ttggcttatc ctaacaccta tcagtcagaa ttactttact tatgctgttt
     5821 cttgtacttt gcttttttgt agtattcctt atacagttgg atttttaaat aaattatcga
     5881 aaacaacaat taaatatcta ctattatttt taacaattgg attagttggc tgctctactc
     5941 tatttaataa agacccgttt gcattacaga atggacagag tattttatgg attttttatt
     6001 tatttttaat gggttatggt ttgaaagaat ggaactggaa agaaaaggtc cgctataagc
     6061 ttcctcaagt atttatcagc ttgattgttt tattcggttt gattattttg atgacacaaa
     6121 tttcactcat catcagagga aatacagata cagcgctgag gttttctaaa ccatattctc
     6181 tcttcgcaat gtattatact ttctcttcgt ttttattttt agaaatgcta tctgataaat
     6241 taggtataaa aggaagagga aattttcttg ctgtattttt gattgtcact caagttatat
     6301 gtaatttccc tttagtttct tatcgcgtat ctacatttat gaaacgtgaa tttccaaact
     6361 cagggaaggc atggctgata aatatcgggc agttttttat ttgctattta ttagcagtgt
     6421 ccctcctagt tatcttttta ttttatatac aaaaaatccg tttcattcat cgtttcatcg
     6481 aatacttcgc ttttgattcg attgaacaat taactcagcg ttggaaaaaa agaattcatt
     6541 ggctttttgt tcataaaagt tattttttag ttgcagcatt tttttactgc tttaccttcg
     6601 tgcagatttt cgttttagaa ccaaaagaag gttggaaaga aactatccag gttgccttaa
     6661 aaatatttac tcagcgacaa gcacccatga tcctgacaat catcattatt atgggatttt
     6721 tcttcttact attgttgatt tccaatcgtt tttggtacgc cttgactgct accttgatca
     6781 ttaacttact gctcactatt tcgacagtaa tcaaaatgga aatgcgggaa gagcctgtct
     6841 ttccttcaga tttaaaaata ctgaccggat tgtcagaact attatcgatg gttagcccag
     6901 tcttattaat cgtgggcgga ttgatccttc tcctattatt gattactagt attattgtac
     6961 aacgtagact acaaaaacag tattccttga agattcattg gaaacgtcga tttatcagta
     7021 tcgctgtatt attaggatgt ttttcgggtg tctttttcat taatcacaaa aattcgcctt
     7081 ctttcttgct gtttaattta tttaaagtaa acaagacttt ctttaaccag caaggcgccg
     7141 taaaagataa cggaccagtc attcaattcc taaacaatat cgacattaaa atcatggaag
     7201 aacctgctgg ctattcgaaa gaaaaaatta atggaataat gaaaaagtac aacacaaagg
     7261 cagatgaaat caaccaaaca agaagtgact ggttaaacaa tcagacgatc gttctcaatt
     7321 taagtgaaag cttcagtgat cctgcacgtg tccctaatct gacagtacct acagacccta
     7381 ttccttacat caaaagcatt ataacagaag gaacaggagg attgatgtta tccgtcggtt
     7441 atggtggcgg aacagctaac atggaatggg aaggactgac aggcttgagt atcagtaacc
     7501 tgtctgcttc gttagttaca ccttataccc agctagtgga gcgtcagaaa ataagtccaa
     7561 atattaccga tctattcgat gaaaaaatag ccatccatcc ttttacagct gctctttatc
     7621 gcagaaaaca agtgtttgat aaatttggtt ttgacaggtt ctattattta gacagtccgg
     7681 ataaattaac ttatacggat aaaatagaac aaagcccacg catatcggat gattcagcat
     7741 acaaagaaac cttgaaagct ttacaaagca atacagaaac gtcacaattc atccaattat
     7801 ccactatgca aaaccatatg ccttatgatg attactatag tgaattgaac tacactgctg
     7861 aaggaactgc tgtcattcct aatagaagaa aagaattaca aacttatatg caaggccttc
     7921 actataccga tacagcagta aaaaaattca tccaagaaat cgacaaaatc gataaaccga
     7981 ttacctttgt tttttatggt gaccatttac ccgcaatcta tagtgggaat gattcgaaaa
     8041 aatatggatt agaacagcac cagacagatt atttcattta taacaacaag tatagtcgtg
     8101 aacaagcagc tacgttaaat aaagaagttg ttgctcctaa taactttggt gctatggctc
     8161 ttgagcatgc gaatatcaaa gtaactcctt actatgcgtt gttgacagaa gtatctaatc
     8221 atctacctgc attaacaatt gatcctacag aaagcttgtc taatcgtttt aatggaaaac
     8281 aggtctttgt tacagaggat agtcaaatta tccaagaaaa aaatttaact gagaaacaaa
     8341 aagaaattct agaagattat cgtctgatac aatatgatct tgttgcaggt aaccagtaca
     8401 gtgcaacatg ggcgacacaa aaaa
//
LOCUS       DAFENC010000078         8106 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.082, whole genome shotgun sequence.
ACCESSION   DAFENC010000078
VERSION     DAFENC010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8106
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.082"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..307)
                     /locus_tag="LP493_002651"
     CDS             complement(<1..307)
                     /locus_tag="LP493_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL2134756.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNF
                     LKCGGTALEYFEQYKENKRRCGRTEIIFPAEEKEYIEKRSTEGWTPDVIIGRAERTFS
                     "
     gene            950..1513
                     /locus_tag="LP493_002652"
     CDS             950..1513
                     /locus_tag="LP493_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2134757.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
     gene            complement(1792..2079)
                     /locus_tag="LP493_002653"
     CDS             complement(1792..2079)
                     /locus_tag="LP493_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBL2134758.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(2069..2398)
                     /locus_tag="LP493_002654"
     CDS             complement(2069..2398)
                     /locus_tag="LP493_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL2134759.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            2703..3032
                     /locus_tag="LP493_002655"
     CDS             2703..3032
                     /locus_tag="LP493_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2134760.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            complement(3319..3804)
                     /gene="vanZ"
                     /locus_tag="LP493_002656"
     CDS             complement(3319..3804)
                     /gene="vanZ"
                     /locus_tag="LP493_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HBL2134761.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(3957..4868)
                     /gene="vanY"
                     /locus_tag="LP493_002657"
     CDS             complement(3957..4868)
                     /gene="vanY"
                     /locus_tag="LP493_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HBL2134762.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            complement(5296..5904)
                     /locus_tag="LP493_002658"
     CDS             complement(5296..5904)
                     /locus_tag="LP493_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HBL2134763.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            complement(5910..6941)
                     /gene="vanA"
                     /locus_tag="LP493_002659"
     CDS             complement(5910..6941)
                     /gene="vanA"
                     /locus_tag="LP493_002659"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HBL2134764.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            complement(6934..7902)
                     /locus_tag="LP493_002660"
     CDS             complement(6934..7902)
                     /locus_tag="LP493_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HBL2134765.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
BASE COUNT         2457 a         1608 c         1360 g         2681 t
ORIGIN      
        1 aagagaaggt tcgctctgca cggccaataa tgacgtctgg ggtccaacct tcagttgatc
       61 ttttttcaat gtattctttt tcctcagcag gaaaaatgat ttcggttctc ccacaacgtc
      121 gcttattttc tttgtattgt tcaaagtatt caagtgctgt tccaccacat ttgagaaagt
      181 tatagacatt gtaaattgtt tggcgtccac gtttaagctg cttcgcaacg atagcaaccg
      241 gagtttcttg atgaaaatat gcttctatca ttacaagctc gtttggtgta agatgggtat
      301 aagtcattta tgttcactct ccttgtatgc tttagcgggt attacaattt gagtgtaaca
      361 taaatggctt ttttatttgt ctcgcttaat tatacaaacg gcgaagttaa aactttttta
      421 gcagatttta aagtttcgtc aaaactaata tattctggta gctgagcatt caaatagctt
      481 tcagacttca gaagaaaatt acgagcattt ttatagtcca tctctaataa agttattctt
      541 tttttatcca atacattcag ctcaattcct tataatattc tattccttag tatctcaaca
      601 ttatttactt tataaaacga ataaattttg tagttctaat tcaaatattg catgttatat
      661 ctaatatggg agcattttat aattttcatt gtgataaact cgttattaac tttaggatac
      721 actagttagg attaaattag gtatctagaa atttacttaa gatttttttg tttatttcgt
      781 atacacactc gtatcaaaaa caatcgatta tgagacaaaa tgaaatgacc tcttttatta
      841 aataaaagag gtcatatttt gtatcataac ttgttgcatt aactatgtat ctataactcc
      901 cttttatgat acaatcaagc cagaattaaa gtacgaaagg aagaaaagca tgagtggata
      961 catttatggt tatgcccgag tgagtacacg ttcacaagaa ctaaatcgtc aattagactt
     1021 actcaatgaa caaaattgta atgaaatcct aactgagaaa atgacgggaa ccaaagcggt
     1081 tcgtccccaa ctaaatcgtt taaaagataa aattcgtccg ggagatacgg taattgtaga
     1141 aagtttttct cgattgggtc gtagtacaaa ggatttgatt gaccttgtta cctattttga
     1201 agaacaccat gttaagctgg tgagcttgaa agaaaacttc gataccagca cgcctcacgg
     1261 acgcttaatg atgactgtct tccaagcatt tagtcagttc gaacgtgatt taattgttga
     1321 acgtaccaaa gaaggtttga aaagtgcacg tgcgagaggt cgtaaaggtg gccgtccacg
     1381 agtgaaccag aaagatgttg atcgagcagt aaaattgtat aaaagtcagg tttatagcgt
     1441 aaaagaaatt acggaaatga ctggtattag caaggcaaca ctctaccgct acttaaaaga
     1501 caatagggaa taatctattt taatctttag gaatctataa tatttatggg agaattagag
     1561 tgattttttt attattacta aaaaacaata taaaataacg cattttaagc cctctttgtg
     1621 cataaggatg aagcttttaa tttgaaagag gcttaaaatg cgttttaatt ttttctattt
     1681 ttcataaata tataggttag tggtttaaaa ttatagggta ttacaactct cagctgttaa
     1741 aaattatctt ttaaagtgtc gtctatcctc tcaagttgaa acattgggtt cttacctaat
     1801 cttttttaat tgttcataaa aattttcatg cgttccacat agtaagatag gtatcactgc
     1861 attatcttta atttcatatg caacgcgata tgtcgtacct gcatacttga atccaatagc
     1921 ccaaattcct gataaatcac ccgttttttg ttctcccgaa tgaggacgaa ctgctatctc
     1981 atcataaatt atcgttaaaa attgttcttt taatgttttc tcttttaatt tttttagata
     2041 ctttattacg tgtttagaag gtagaatctc ataagccaat ttctgctgcc aactcctctt
     2101 ttgtcatcgg tttagaattt gcaacagtat cttcagcaat agatttaaat gcagaagtta
     2161 acgcattttt tctatttcta aattctttta agatctcttg tttgctataa ccttctgaaa
     2221 gaatatcagc caaaatatct tcactaaaat caaaaaattc ttttttaggc tctacaaact
     2281 cataaaggat accattctct acaagcttag cttctacttc aacaccattg ggcacatcga
     2341 attctttagg gaccgttaac ataatagaat ttccttgttt tcttgttttt gtaatcatat
     2401 tatttcctcc attattttac atttcgtaat tacttagtaa ttacattgta cgctattttt
     2461 agtagaaata caaaataata aaactccttt agaacaattt tcaaaggagt tttatttgat
     2521 taggaaatta tgtagaataa taatatgttt ttaacttgga atcaaaaacg cacttgcaag
     2581 taagtttact tcaatacatg aaattgctta taatagtgta ttggaattaa ggtagattga
     2641 caaaagagtg atcaaatagg tatacttcat tcaaataatc gtttgaatgt gaggtgagat
     2701 gaatgaaaaa agtttgccaa gtgactgtcg tacataaaga aaaagtaaat ggaataaaaa
     2761 ataaattgga tcaaaaagat ttttcaaact tacttgtgtt agggaaatgt ttcagcgatt
     2821 tttctagaat taaaattttc tatgctttag aaacctataa ggaaatgtgc gtctgtgatt
     2881 tagcagaaat acttactgct agtgtcgcta caacgtcaca ccatttacgt tttttaaaaa
     2941 aacatggaat ggcaaaatca cgtcaagatg gaaaagtagt ttattactct ttagcgaatg
     3001 aagacatcct ttccgctatt cgtgtttttt aaagttatca gaaaatctat ctatgaaatc
     3061 ttagtttggg ggtaccgtca ggaaaatgcg gatttacaac gttaaggaaa tttattaaag
     3121 agaccaattc ctcagcacta aaattgataa ttgggctttc tttgttacta tagtgttagg
     3181 taagcttttt actttatcac cggttttccc ctcacttcac acctacgggc gagtttcccc
     3241 acatcccgtt ttccatctaa tccaattcat tcaatatctt tatgtgtatg aaagatcaga
     3301 ttgcttgatt tagacatctt acacgtaatt tattcttaaa tgggtacggt aaacgagcaa
     3361 taatacgagc aaaagtatac ctacaaaaat aataactctg tctaattttt tttgattcat
     3421 atgcttattg cttaaaccat ataatttcag tccaagaaag cctccaacag tatttgtaat
     3481 tacatctgtt atgtctgtcg ctccaatagc gaagataaat tgaattattt caaaagtaag
     3541 acttaaaacc agtacaaaag caaacttagg taaaaatccg atttctttaa aattgacatt
     3601 caaaagcaag ccaaatggaa taaagattat aacattatct atcatctctc tgaaattccc
     3661 agtagcagta aatggagtca agttaagact tctttgatga taattaaata ctgataaaat
     3721 attgtattgt aatttgaata acactaacca gattagtgtc actaaatata aagctagcaa
     3781 tcctctagat aatatttttc ccaatataat ttcctctaat tcttttgttt aagttgtatc
     3841 attagtatag caatgtccta gttaacgtgg gttttaaatt aaaaagctaa cgttacccca
     3901 aaagtgctag tacaataatg ctgttcatta atttcgttgg tttcattccg ccatccttac
     3961 ctccttgaat tagtatgtgt tgatccggga aacactgtca caattacacc gtctatattg
     4021 tttcctgata tctcataacg aagattagtc ggcacatgaa tggtggtatt tttagtaaca
     4081 ggataataaa agatctcata tttttcccca tttacactaa cagaaatggt tttttcttct
     4141 tttaggtaat ccatatattc ctcgagaacg aaattctttt ctttcataat cgcactatgt
     4201 ggtaaaccaa catagcgaat atgccatagt tcatattgaa ttcctgttaa ctctgttttg
     4261 tcctctggat aacgtaaaat gaacccgtat ttccaagcat tttcttctat ccactttcct
     4321 tcaggggctc gttccatttt cgtcaagctt gatcctacat ctagtgataa acctgaatta
     4381 tgctcactat aacctgctgg taaggcatac tcagccccca tttcttggta aagcacactt
     4441 tgctcatcaa agtctcgata gccactatta ataataaaat gactaacgcc accctttaca
     4501 gcatcattga ccatctctga aaatttttgt gctatttctt ttgacatata aatattacta
     4561 tcaagcaacc cgtatccatt tattaattcg tcatgtttag ataaattcac gatatctgac
     4621 ttcacacttt cttggcgaac aggatattta ctattgatta atagcagatt tccttgataa
     4681 acctgttctt ctgtaattgt tttctcttgg gtattttcag aagtcccact attttctaaa
     4741 tgttctttgg gattttgatc ataattttga aattcgactt tttcctgaga aaacagtgct
     4801 tcattaacgt agtcataacc taagtatatt aagaataaca ataacaataa aaaaaacaac
     4861 ttcttcattt tcagtctcct ccttaactat atagttggaa gtatgaaata tttctagaat
     4921 cttcccctta aacggcacaa tctcgtttga gattgtgccg ttttgccccg taaattacag
     4981 tcaattattt cgccctactg gatttactat tatcaccaat gtagatgaat tttcataagt
     5041 gatacccatg ctgaatttaa cgaggctgaa ctgcctgttg acaatgggcg gtgtgaaata
     5101 ccacccctct atgcgatcag tcttattatc aggctatctt gccgcagcgc acgcagataa
     5161 tgaccgcaat atcgctctgc cttacatctt caatactatc tactatatat aaattcccta
     5221 agaaccagtt acatacgtcg ggtttcctgc cgaaagagtt agcttatata gtttgtccgt
     5281 gcaacggtta aaagtttatt taacggggaa atcaaaatag ctattggggt atggttcgtc
     5341 tcttaataca tagtgccacc attcgaggct atatgcttca aacccactgt tttccatgat
     5401 ggagcgcaaa cgtctgcgat tttgcgcttc attgcatgat attccatttg ccgcatgatg
     5461 agagcgttca tccataaaat caaatcggct ccccattggt acaagctcac ccgtgtctaa
     5521 tcgataaagc gtaagatcaa tggcactgcc gcggctatgg cttgattttg aagccacgta
     5581 tccttttgaa atcatctcag ttcggtcaat attgggataa taactttcct ttgtcaggtt
     5641 attttccggc tgtgcagccc attgcataaa acagtttaca gcacgattag gacggtaacc
     5701 gtcccataga agcaatccgt acccttgggt agcagccagt tcttttgcct tcaaaagcga
     5761 ttcagccaac tcgtatgtcc ctacaatgcg atttacttca taaccgtcaa ccggttttcc
     5821 ggtgaaatta tcccaagtgg catatttagc gtcccaacga acaccgtgta ctatttcatc
     5881 taaaaaagta aatcctattt ccatgcttat caccccttta acgctaatac gatcaagcgg
     5941 tcaatcagtt cgggaagtgc aatacctgca gcggccatca tacggggata acgactgtat
     6001 gacgtgaaac cgggcagagt attgacttcg ttcagtacaa tgcggccgtt atcttgtaaa
     6061 aacatatcca cacgggctag acctctacag ccgagcgctt tatatatttt ttttgccgtt
     6121 tcctgtatcc gtcctcgctc ctctgctgaa aggtctgcgg gaacggttat aactgcgttt
     6181 tcagagcctt tttccggctc gacttcctga tgaatacgaa agattccgta ctgcagcctg
     6241 atttggtcca cctcgccaac agctaacgcg gcactgtttc ccaataccgc acaaccgacc
     6301 tcacagcccg aaacagcctg ctcaattaag attttgctgt catattgtct tgccgattca
     6361 attgcgtagt ccaattcgtc cgcgctattg acttttttca caccgaagga tgagcctgaa
     6421 cgcgccggct taacaaaaac aggataggta aacgtagctg ccaccggcct atcatcttta
     6481 ttaataaccc aaaaggcggg agtagctatc ccagcatttt tcgcaacgat gtatgtcaac
     6541 gatttgtcca tacaaattgc tgagctttga atatcgcagc ctacaaaagg gataccggac
     6601 aattcaaaca gaccttgtat ggatccatct tcacctgact tgccatgcaa agctgaaaat
     6661 gctacatcaa catggttgat ttcatattca tggttctttt taacaagtaa tccgtgcatt
     6721 tttttatccg gcgagagtac agctgaatag caattgtcgt tttcccattc cgcgcaaggt
     6781 ttttcgcaca ttttccatac accagatttc gtaattccaa tgtataacgg ctcgtatttt
     6841 tctttattaa tgttagcggc tatctctatt gcagatttta ccgatacgtc atgctcctct
     6901 gagcaacccc caaacagtat tgcaactttt attctattca tgctcctgtc tcctttcaaa
     6961 atccaaacag tttttaatgg ttttttcaac ggtatcacgc aacgcttgct cggtataata
     7021 ggccgtatgc ggtgtgatta tcacgttagg cattctttga agtttaagta aaaattgatt
     7081 atcaattggt ttttgggtgc aatcagagta gaaaaactct tcctctcctt ccaatacatc
     7141 caatgcggca ccgcccagtt tcccgttttc taatgcttta accaactcat aggtatctac
     7201 aagtggaccg cgcccagtat tgataagaaa tgctccttgc ttcattctct gtatttgttc
     7261 gtggctgata atatagtgcg tatccgtatt gagcggcaca tgaagcgtaa cgatatcgct
     7321 attttgcagc aactcatcaa acggtacata gtttacctct atacttcggc tgcgactata
     7381 agccaacact ttacatccaa atcctcgcag ccgctcaata accgctttgc ctatctggcc
     7441 cgttcccacc acaccaactg tcatgtcgct gagtaccttg ccacggtcgc tgtccaacct
     7501 gaaatcatgt ttttccacag agcgcacaat cgattttacg ttgcgtactg ccataagaat
     7561 tagcatcata gtataatcgg caacgctatc cggcgagtac gccacattgt cgacagtgat
     7621 gcccattctc ttagcagcag ttgtatctat atgattgcag ccgatgcttc gggtagaaat
     7681 atatttcaca ccggctctct tcagcgcaag aagaatagag gcggaaatct ctgatttatg
     7741 tcccacactg atacattgat tgaaaggcgc ggatttggcg ttggattccg acacgttggc
     7801 gttaattatc gttgccataa cgccaaagcg aggcgaaaga gcatggaatg catctgcctc
     7861 atcctgctca catccataaa cagtaatgcc gatgttattc ataattaaga ccaacccttt
     7921 ctgtgaaagg caccaaataa aacggggatg ccaatggtaa tcttgtcaaa tctttctctg
     7981 aagaacgaaa acggctcgtt cttacggtat taagtctacc gtgtaagaac gagccgtttc
     8041 ttaatattaa attgttaatt tcctaagaaa aagtaaagat aaccttgaga ttttcctaaa
     8101 aaatta
//
LOCUS       DAFENC010000079         7916 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.084, whole genome shotgun sequence.
ACCESSION   DAFENC010000079
VERSION     DAFENC010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7916)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7916)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7916
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.084"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            1..329
                     /locus_tag="LP493_002661"
                     /pseudo
     CDS             1..329
                     /locus_tag="LP493_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(231..947)
                     /locus_tag="LP493_002662"
     CDS             complement(231..947)
                     /locus_tag="LP493_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBL2134766.1"
                     /translation="MIKEKIDSFVTIDDLQVGKPDPEGYLLCLKRLRVEQAVVVEDSP
                     VGAQAAPHMTVDVQALDADFFAFSGHKMCGPTGIGVLYGKRQLLEQMEPVEFGGEMID
                     FVNLYDSSWKELPWKFEAGTPNIAGAIDYLNEIGMENIHRYEQELVAYVLPKLQAIGG
                     ITIYGPQDPEHHTGVVAFNLDGIHPRDVATALDMEGVAVRSGHHCAQRFIDDFCLTNW
                     SFKQSMIMPFERLQCRGIFE"
     gene            complement(1071..1256)
                     /locus_tag="LP493_002663"
     CDS             complement(1071..1256)
                     /locus_tag="LP493_002663"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134767.1"
                     /translation="MTKALIFDFDGTMIDSEWMFYESIHHYLLKPIYWSSSAIKFLLQ
                     TINKVLGRQQNCPFMKG"
     gene            1483..2756
                     /locus_tag="LP493_002664"
                     /pseudo
     CDS             1483..2756
                     /locus_tag="LP493_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(2863..3894)
                     /locus_tag="LP493_002665"
     CDS             complement(2863..3894)
                     /locus_tag="LP493_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2134768.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(3901..4731)
                     /locus_tag="LP493_002666"
     CDS             complement(3901..4731)
                     /locus_tag="LP493_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2134769.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(4728..5543)
                     /locus_tag="LP493_002667"
     CDS             complement(4728..5543)
                     /locus_tag="LP493_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBL2134770.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(5540..6364)
                     /locus_tag="LP493_002668"
     CDS             complement(5540..6364)
                     /locus_tag="LP493_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HBL2134771.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(6354..7454)
                     /locus_tag="LP493_002669"
     CDS             complement(6354..7454)
                     /locus_tag="LP493_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBL2134772.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            7632..>7916
                     /locus_tag="LP493_002670"
     CDS             7632..>7916
                     /locus_tag="LP493_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HBL2134773.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPY"
BASE COUNT         2368 a         1908 c         1461 g         2179 t
ORIGIN      
        1 actcagatgt tgaaagtcaa agaaaagttg actattttag aattaaaacg tacccgtttt
       61 ctatgctatg attgtgggca gaccttttct gcgaaaacgg acttagttga tgaacatcat
      121 caactaacaa aggaactgaa acaggcgatt ctcatagaac tgtacgaaaa tcaatcacgt
      181 aatctgaaaa tcagaagaag taccgtcggc tcaagcgata ttggaaactc ttactcaaag
      241 attccacgac attggagccg ctcaaacggc attatcatcg actgtttaaa cgaccaatta
      301 gtcaaacaga aatcgtcgat gaaccgttgt gcacaatggt gtcctgaacg tacagcgaca
      361 ccttccatat ccagagcagt cgccacatca cggggatgga tgccatccaa attaaaagca
      421 accacgccag tatgatgttc aggatcttgc ggtccgtaaa tggtgatacc gccgatcgct
      481 tgtaatttag gtaaaacgta ggcaaccagt tcttgctcat aacgatgaat attctccata
      541 ccaatctcat tcaagtaatc gattgctcct gcaatgttcg gagtaccagc ttcaaatttc
      601 catggcagct ctttccatga actatcgtaa agattgacaa aatctatcat ttcaccgccg
      661 aattcgactg gctccatttg ttctaacaat tgacgtttgc catataatac accgattcct
      721 gtcggcccgc acattttatg cccgctaaag gcgaaaaaat ctgcatccaa cgcttgtaca
      781 tcaactgtca tatgcggtgc tgcttgggca ccgactggac tatcctcaac tacaacagcc
      841 tgttcaaccc tcagccgttt caagcacaac aaataacctt ctggatctgg tttgccgacc
      901 tgaagatcat cgatcgtcac aaaggaatca attttttcct taatcatcgg atgtgcttca
      961 aaaaaatagt ctagctcccg cagttcagaa ttgagactac tccgattttc cagtgctgct
     1021 gatccgctgc tcaaaatgtt cagcatccac tggtctccca accgcttgac ttatcccttc
     1081 ataaaaggac agttctgctg ccgtcccaac accttgttga tagtctgcaa aaggaatttt
     1141 atagccgaac tgctccagta aataggcttc agtaaatagt gatgaatact ctcgtaaaac
     1201 atccattcac tgtcaatcat cgtcccatca aaatcaaaaa taagtgcttt ggtcatcttc
     1261 tttccccctt acccaaaaca agcaaaagct gtgtcctgct ctctctacag tatcagcata
     1321 aaaactgccg tctgaaaagt caaaggtgaa agaaatgtgg cgctataatt tctaggactg
     1381 atagtaaatc attctatcag tccttttgag cataaaaaaa caaaacatac agaagctccg
     1441 ttagaattga atcaccacaa cacaatcaaa ggagcgttct gtatgcctga tcttcatctt
     1501 atcaaactat tactaggaat caaagatgga aacattcaaa tcactcatgt cgagaagaaa
     1561 aaaatacatt caatcaacag tatcgttgtt tctgccacgc tcattaaaac gattcagccc
     1621 tgtcctcagt gtaaacaggt gaatcaacat gggctgatcg ttaagaacgg aaagaaaaaa
     1681 tcgctggtcc ttctcaataa gtgtgcgaat caacggactt atcttgcttt ggcaaagcaa
     1741 cggtacctct gtcgtggctg tcacacctat tttacggcga atacctacat tgttgaaaaa
     1801 aactgtttta tcgccaaaca agtacattat aaaatattgg aggaattgac tgaaaaacaa
     1861 gcaatgacga cgatttctaa acattgcggc gtttcttggt caaccgtttc gcgaacactc
     1921 gcttctctgc tccccatgac aaacgtgaaa ataaattggt tgcctcgctg ttcattggta
     1981 gatgaatttc gttcattgaa aaatcaagtc ggtccctatt ctttttcttg tatggatggc
     2041 gatactggga aattactgga tattcttcct tcacgtaaga agaaagatct catttcttat
     2101 tttatgcaat ttgaacgacg tgcacgttta aacgtaaaaa tactcgtaac agatatgaac
     2161 gcctcttatg ctttgctgat aaaagagtgc tttcctcatg ccaaactcgt tgtggatcgc
     2221 tttcacatcg tcaagcacct cattcgcagt tttaaggata tttgactatg agtcatgaaa
     2281 agcttcgacc gaaacgatcc aatacaagcc aaacactatc gacaagtgaa ggctttatct
     2341 cgacttctga tcaaacgaca ggacacgctt gtttatgata aatggacaaa atggcgtaat
     2401 tttggttggg cctatttaac cgaaagtgaa gtcgtagaac gtctactttc tacttctgat
     2461 gaactacgaa tagcttatgc ttactatcaa gaaattcttc aagcttttta tgacaaagaa
     2521 gcggacatct tctttcagct tgtaaaaaca atgcccaagt cggttccaag agaactgcat
     2581 catataaaaa aagcgtttat aaactatgaa tccggcattc gtttagcctt agagttgcct
     2641 tactcaaatg gcaaaataga aaatctgcat acccacatca aagcattgaa acgaatagct
     2701 tacgggttag gatgagaacc agaattttct taatcaatca tctgatcact tattaaacat
     2761 aaaaaaacat ctaaagcaga aaatcaattc taccttagat gttcttatat cactctatca
     2821 gtcctatttg acaaagagcc agaaatgttt gccgactata cactagcttt gttgtgcaaa
     2881 atgctgagta tcaatttcca cagggattgc tagaatatct ttcagctgaa tgtataaggc
     2941 atcgctaatt ttctcttccc gatcgttcaa ccgatccact aaaatttctt tgccctccag
     3001 cgtttgaaaa acataccgtt gaatgttgcc taaaataaat gattccttcc atagaaccgg
     3061 aatcttaacc ccctgaggaa ccggttcaaa ttgaatcagc tccggtctta aataataaat
     3121 gcagcgattg cccttagcgg aaaactcgtg ggtatactga ttcagctcat accattcgaa
     3181 acgattatag ttgccgataa attccgcaac aaatcggctc tgaggattct gatacaattc
     3241 tttcgaggtg gaaacctgag ccacccgccc agcttccatc acaaaaatcc gatcactgat
     3301 tcgcatcgcc tcttcttggt catgagtcac aaaaatcatc gtcatcccta gcgattgctg
     3361 gatagcgcgc aaatcccgct gcagctgttt tctaattcgg gcatccaaag cacttaatgg
     3421 ctcatccagc agcaggactt tcggttcagt gaccaatgag cgagccagtg ccacccgttg
     3481 tcgttgaccg ccagaaagaa actggacatt tttatctgcc tgctccgtca tatccaccaa
     3541 tgatagcatc tcaaaaacct tttcctgaat cacctcagga ctcagcttct ttaccttcaa
     3601 accaaaggct acattttcaa aaacagtcat agttggaaac aatgcatact gttgaaaaac
     3661 aaagccgata ttgcgatcct tcgtaggctt atcggcaata ttctcattgt ccagcacaat
     3721 ctcaccgctc tttggttgtt ccaatcccgt gatacagcgc agcaacgtag actttccgca
     3781 cccgctggga cctagtaaag taaccagctc acccttttca atctgaattt catcaatagc
     3841 taaaatctgt ttttcatcaa aaaacagatt gagatcatgt atttctaaaa acattttccg
     3901 tcacaactcc tttaagggct tctttttcga ctgcttctct tccctcgtct gcttaaggga
     3961 cagctgttgc ttttgtcgat aagtcagcat aaaggtagtt aaagcaattc ccaccataaa
     4021 cagcaaatac aaaaccatca cagcgctagc caaatggccg ttttcgttca tccgccgcag
     4081 catatagatg cgtaccgtct gaaatcgacc gccaatcaac aggttcgtca gcatgtactc
     4141 cccaaaaacc gaagaaaaaa tcatcagaga aactagggtc acaccgatac ggatgtttgg
     4201 aaacagcacc tggataataa tcgtagacat cggggcgccc aaggtttctg ctgcatccac
     4261 taattccttc agattaatta agcgcatctg gttgttaaga ctaagataga caatcggcaa
     4321 cgccgtaata aacaatgcac ctaccaacac tacaaacatt gggataccag tttcagcata
     4381 cgttcgaagc aaagccgtta ccaaaatcac tcctggtaaa gcatacggca gcaggagcag
     4441 cttttccagc caacgattca aacgagggaa atacaaatga atccaaataa tggtgggaat
     4501 catcaacaac agaatcgtca ccaagaccac acctgctaat aaaagtgagc gacccaccgc
     4561 agcaataaat tccctgtccg tcagcagctg ttggaaccat tgcaaggtaa aatcactagg
     4621 taaaagcgat tttgaccatt tagtggagct ggcatacaaa atcgttccaa taatcggcag
     4681 caagtaatac aggacaaagc agaacaaaat cggttttatt aactttttca cgtctgcacc
     4741 accttgcctt tcttttgaat aatcaacatt gccgttacca gcaggacacc taaagcgact
     4801 gccaacgcac tgcctaaatt aggcttggcg aacacatctc ccgacactaa agccgcaatt
     4861 cgaatcgtta aaagatttac attactgctg gtcagggcat acgctgtttc ataggtcccc
     4921 atgccattag caaataagat gacaaaggtg ctggcaatcg atggtcgcaa aaaaggcaaa
     4981 gccaccttga accaagcata cgctgatgaa gcgcccagca attgtgcgga ctccagccat
     5041 tcctttttca cttccttcat gctgggatac aaaaacaaga cccctaacgg aatttggaaa
     5101 taggtatacg tgatggtcaa tccccaccaa gaatacaaat tgaagtccgc tagaaatggc
     5161 aaaatcattt tcagcacacc tacattcccc aacaaaataa taaaagagaa tgccagcgga
     5221 atcccagcaa aattagctgc caaattggaa acaaaggtga ttttctcctg caatttagtc
     5281 gatagattca ttaagcataa acataaaata aacgtcccga ttaacccaat cacactggag
     5341 ctgacagcaa tcagtacgct gttaacaaag gcctgtgtgt aatatttgtt gctgaaaata
     5401 tcactgtaat tggccaatgt ccactggtta gttaaatcac tgtgcaagct gcacagaacc
     5461 ataaaaagca gcggcagcag taaaaatgca cagaagataa aggaggcagg aaccagaacc
     5521 aagcgttttt tcatctcttt catcccctca tcaattcttg aatgtcctgc attttctctg
     5581 acggtgcaat tcctaataac cagcaaaaca atggagccgc cagcagctgt ggtacagttt
     5641 gttccttcag cttttggcgt ttatttgaaa tcaaataaaa aggaacttca cgatgtgcag
     5701 ccaagctgcc gccatgcagt ccgtgcgcat ccatcccgtg atccgcagtc accacgactt
     5761 gataaccttt ttgcagccat tcaggaaggt aaatagccaa taatctgtcc gcctgattaa
     5821 ccgctgctgc atattcatga gaatcggcgg taaatttgtg accgacatca tcaatattca
     5881 tcgaatgtac gaccaaaaag tctggctgat actgattcac taaataatgg gcatccgcaa
     5941 ataaatgcga atcagggtaa gtgtcctcac tataaaagat gccatgctga atcagtcgct
     6001 cctcctgatg ctggatgcga tcaaccaaac gattataggg ggcttgattg tacaactcgc
     6061 tgtaccagtg gtaagcggcg gctcctgttt ttccgccagc ttccttaact aattcaaaca
     6121 gcgaccactc tttggatcgc tgagcatggt aattactata gatgccattt tcataggctg
     6181 gaacgccggt catcagtact tcgtataacg gacgtgaatt gctgggcagc tcacttttta
     6241 ccttcaataa gcttgcttgc tggtgctcaa ctaaatgatt catgaaccca agctgggcga
     6301 cggctgtgtc gtagcgacag ccgtctagta taactacaat cagtttgtca agtctacttt
     6361 gcataggtca gtacctccgc ctgccaaagc tctggaagct ctacagaggt cttgttccaa
     6421 gcttcattgt cttcaactgg caccgccgct tcataagcat cctccggcag taatttttca
     6481 gctacttctt taggcagctc taccttgcga ataggtcgcg catagccctt tgccaaattg
     6541 atttgccctt catcagataa aatatattcc cgtgctagct ttgccgcatt gggatgaggg
     6601 gcatttttat tgattaaggt tgtatacccg ctaatgatgg agccgtctgt tggcacagtt
     6661 acctcaaaac gctcggagtc aatttggtca cgataattta gtccattgaa gtcccaaaca
     6721 actgccacat cgatttcacc tttttcaaga tttgctacgc tggcatcaac ggtggacaaa
     6781 cggccttttt ctgccatttt tttgtagtaa ttcagacctg gctgaatatc cttttcgtca
     6841 cctccgttgg caatcgccgc agccaataca gcaaattgtg cttggttggc aatcgtcaca
     6901 tcccccacgc taacttgata gtcaccctct tgcagctcct tccagctagt cggtgcttgc
     6961 ttcacattct ctttatcggt gataaaggaa atggttcccg tatagcttaa caaccaatcc
     7021 ccatcatcat cctttgccca atccggaatt tcctcccaat agttggtctt ataaggtaag
     7081 gttaactctt tgctttcagc caacggaccg aagctgatac cgacatcacc aatatcggcg
     7141 gttccatttt ttccttctga ttcaaactta gccaattctt ctgcactgga catatccgta
     7201 tccacgtgac ttaagccgta ttctttttca aggtcgttcc aagtgcctac ccaatttgcc
     7261 caagtatccg gcattcccaa gctggcaatc tctccttctt ccttggcttt ttctataatc
     7321 gtatctaaag agtcgtctgc cgcagccgat tgcttcgttg cttcacctga gccgcagcct
     7381 gtcagcagga tacttactgt tgctgcacaa aataaaccga tagtcatgtt acgaattttt
     7441 tcattcattt tcattcattc ttctcccctt tcgataattc cattctaaca aagctttgta
     7501 atgagagaat cagtttcttg aaaaggtttc atgaacaatg taaaggttgt atatggtttg
     7561 taaatttcga cgaattcccg ttaaccttct aaagcttttg cggtatgata gtagaaaaaa
     7621 ggaggctccc tatgcagtat tatgatcagc atctccacac gtatttttcc tttgattcag
     7681 aggaaaaatt tgaaaactat ttagcctatc agccggagtt tttcgtttct acggatcact
     7741 ttgatttaaa caatccatct accggaaaag atgacattcc ggattatcca gcctatataa
     7801 acaaactgga ctctttaaaa gaaacctatt ccaccaaatt tctgcgaggt atcgagattg
     7861 gcgttgttcc aggacaagaa gagcggatcg tggattacct cgctcagcat ccttat
//
LOCUS       DAFENC010000080         7599 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.085, whole genome shotgun sequence.
ACCESSION   DAFENC010000080
VERSION     DAFENC010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7599
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.085"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(941..1354)
                     /locus_tag="LP493_002671"
     CDS             complement(941..1354)
                     /locus_tag="LP493_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HBL2134774.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1810..2295)
                     /locus_tag="LP493_002672"
     CDS             complement(1810..2295)
                     /locus_tag="LP493_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134775.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2434..2649)
                     /locus_tag="LP493_002673"
     CDS             complement(2434..2649)
                     /locus_tag="LP493_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HBL2134776.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2873..3673
                     /locus_tag="LP493_002674"
     CDS             2873..3673
                     /locus_tag="LP493_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL2134777.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3692..5560
                     /locus_tag="LP493_002675"
     CDS             3692..5560
                     /locus_tag="LP493_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBL2134778.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5553..6044
                     /locus_tag="LP493_002676"
     CDS             5553..6044
                     /locus_tag="LP493_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HBL2134779.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6032..6586
                     /gene="srlA"
                     /locus_tag="LP493_002677"
     CDS             6032..6586
                     /gene="srlA"
                     /locus_tag="LP493_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBL2134780.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6604..7599
                     /locus_tag="LP493_002678"
     CDS             6604..7599
                     /locus_tag="LP493_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBL2134781.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2708 a         1213 c         1443 g         2235 t
ORIGIN      
        1 tgttactatg aataacataa taagaaagta aagtggattg atttgagatc tttttatact
       61 tcaaaaaaga taacacccaa ctttcaaaaa tatgttttgg aagttgggac aaacgagtta
      121 atacatttta atacattatt ttttattcaa aaaaaatagc acaatggcaa agatcgtaag
      181 agagatcata agccccaatg aatgactaaa aagaaaagca gaatcacatg ccatatcatc
      241 ccatatttct tcaagaaaat aaataagcgg gaaaaaggga aggaatagta gaacatcgat
      301 ccagcaccat ttttttcttc ttttgaaata acataaaaca ataaacatga acgtgcaggg
      361 aagtaaaaac aaagctttac tcataactaa caaaatacca gctcctttta tttttttctc
      421 ccccacattc aaagagtaac aatggtatgt acttaataat agaaaaatgg atcaacttgt
      481 atgaataaca gctgaaaaga tctgcaccaa ataaaaaact tccagccaaa actgactgga
      541 agtttatttt tttctgaaat attctaacac aaatatgaaa aagatggccg aagctaataa
      601 gccgatttcg tagcaaaaca atgagatacc agagtcgtaa taataaaatc ctctaatctt
      661 atggataaaa tagatcatcg gacaagcaga taagagtaag tatttgttag gccttttgaa
      721 taagtaaaag aaagcactgg tcattatgat aaatggtatc caaaacaaaa gtttacttaa
      781 gacaatcaaa tgatcaactc ccatattttt taccaagaga gatcataaca tctttatcgt
      841 aaaaacaaaa tatttttttg ctcattttga aaatttaaac atactcgttc ttatccaaat
      901 atataaaaat cgcccctcat tcatcgagag gcgataagtt ctaatttaac tcaatttttt
      961 ttgtttcttt tggctgataa gctgttttag gtaataccaa tttcagcaca ccgtttttaa
     1021 aggttccagt gattttttct tcatcaacat taggaagata gaatgaacgt ttgtaagaga
     1081 ccgaatgtct ttctttccgt acatagttgc catcttcttt atcttctgta tgggactcat
     1141 gattggcgga gatcgtcaaa gtattatctg aatattcaac tgtcgtgtct tctttgtcac
     1201 agccaggcat atcagcagtt agtttgtatt ctttttcatt ttcgactaaa tctacttttg
     1261 gataacttga aacacctaaa aaatcattga atgctggact aaacacgtca ttgaaatcag
     1321 ggaacatgtc gcgaatgcta ggtacatttg ccatttttga tcatcctttc aataagtatt
     1381 ttttatttat ccctatttac gtaataactc tattttgaaa aaaatgcaag tataatggtt
     1441 agctttgtga atatttcatc taatacgata caaaggctat ctttctaatt tgaaaaaggg
     1501 atcattaaaa taataagaag aaaatatgtc aaaaggtaaa aaagtaaatt cttctatcca
     1561 aatatagaaa aattgaatct agaaaaccgc ccgacaataa atttcattaa ctcagttgac
     1621 cgaaaatgaa gtagatacca aaaatttatc aagagagcaa gtagagaagt gagtatattc
     1681 ataagagaaa tagctgtaac gaattattag gttaatgcaa atgcttattt atactccgta
     1741 taactttctc agaaaaaatg ataccaataa tgacttgcta gtactgtaaa tccgtataat
     1801 atcatctaat caaaatggtg ttccatttgc atctgtcatc gtaatcgatc cttcgggtga
     1861 cactcgataa aaaccaacgc ttccagatcc tccttgggaa cggatttgtt tgctggaagc
     1921 tgtgaacaaa taatctcgat caattttttg ataaaagcta ataacaatat cgtcactttg
     1981 taattcggaa cggtgggcaa taagaaatag aagtgctttg tcagagtttt ctaatggaag
     2041 agaaggtaca gtgctttctt gcatttcaga tgttgaagaa atgctaaacg actgaatact
     2101 tgattggcta tgttgcgaat ctacattacc agtagaagta ttagtaatgg aagtagtaga
     2161 agtactttta gttgaaccaa cctcagttgt tgaaatggct gctgaagatt ctttaacaga
     2221 attctttgtt ttatatccac aggcagaaaa aagtattaca gttcccaaca agcctgcgta
     2281 aatcccttta tgcatgatag ctcctcctaa aatagattat ctttattcag tatatcactt
     2341 aaacaaagaa aagcagatgg tttaaaatga aaaaaccttc ccaataaagg gaaggttcat
     2401 gaagataata acttttttaa taattatagc tttctaatat ctttcatcaa cttttctagt
     2461 aatcattggg aaaaatttca agcagtagat cgcacaaata cctacgacga tataaatgat
     2521 cttcgcaaaa atagttgttg aaccaccagc aatcatagct actaaatcaa gttcgaacaa
     2581 gcctaccaac agccagttca accctcccac aatcaataaa gttaatgcaa tagcatctaa
     2641 agttttcatt agaattctcc tttcttaaat gataaaacaa ttatatatca aaaagagaaa
     2701 cattgcttat ataacgctca ggaattttag caatctatgc aaaaagatga aaattttttt
     2761 tgctcttcca ttagtacaca ttttttagct gaagctgtaa atttcatgtc ttaatttttt
     2821 ttagtgagct tttatactgg atttgtaaga aaaaagaagg agaggatcac atatgtcgga
     2881 ttggttggat attgcaggaa aagtagtaat tgtaactgga ggttcctcag gaattggaag
     2941 aagtatcgtc gaaaatttgt tgaagcagaa tgcacaagta gcgaattttg atgtaactga
     3001 atgccgtata cagcatgaaa acctactatc tttaaaagtc gatgtgtctt ctaaaacgga
     3061 catagaagaa gggatatata aagtaatgaa acatttcaag acgatcgatg gtctagtcaa
     3121 taatgcagga ataaatattc cttctcttct aatagataga aatcatccaa aaagcaagta
     3181 tgaattatca gaacaagttt ttgataagat gatcgctgtc aatcaaaaaa gtgtatattt
     3241 gatgagccaa gcagttggaa gaatcttggt gcaaaaggga tcaggagtga tcgtgaatct
     3301 ttcttctgaa tcaggattgg aaggatcaga aggacagagc tgttatgctg ctacaaaagc
     3361 agcgatgaac agttttactc gttcttgggc aaaagagtta ggaaagagga atgttcgtgt
     3421 ggtaggtgtt gcaccaggga tactggaaga aaccggtttg agaacacaag aatatgaaga
     3481 agctctttct tatacgagag gtataagcgt cgaacagctg agaaacggtt acagtcgaac
     3541 aagtacgatc cctctaggaa ggagtggtaa gctgcaagaa gtggcggatc tagtctgcta
     3601 ttatctttca gaaagatcaa gttatatcac tggagtcacg actaatattt caggaggtaa
     3661 aacaagagga taaaggatag gggggacgca cgtgacgcta gtaaacagat ggtaccaatt
     3721 attgaaatta ctagtcactc acaagaaagt ttcaatccag gaagtgcaaa aagaaatcaa
     3781 aaccagtaat caaaccataa aaaaagatat tggggagttg aatgaagaaa ttgccggtat
     3841 tgcaaaaatc atccaaaaaa acaaacattt tgaacttgaa atttatgatt ttgatttttt
     3901 tgatgagatc atgcaaggaa aattgaaaac agccagtgat ttcaattcgg catccaaaag
     3961 aatcgcttat ttactaaata ggctgatcga aacagaggat ttcttacgta tggatgattt
     4021 gtctgaagaa gtcggtgtca gcagaggaac agtggtcaag gatctaaaga cattaaaaga
     4081 gatgatcaat gattttgatg taaagattac aggcacacca aataaaggac taagaataat
     4141 aggagatgag ctagaattac gactactttt attttatttt gtttctccct acttttcaga
     4201 gacgaaaaca gaacagtttc tagaagaaaa acaagcaatc aaacattttc agaagaagac
     4261 gaatgctagt aaacaagaaa tcaccctttt aacgaaagtt atcggtattt ctttgaatag
     4321 aatctctagt aactatctgt tgaagaagcc catcaatcgt tacagtgggt gttttgaata
     4381 tatccaagaa ttcaatgaac tgatcaatca gttggaagaa atctatgaac taactttgag
     4441 ccaatatgaa aaagatttta tcagttttcc tttgaacatc atcaacacaa gtataacgat
     4501 gataaggaaa gctaactctg atttgcgctt atatttcgac cccatgatga tgcgtattcg
     4561 acgattagat ctcattgatc tggatgagtc cttcttatat caagagatga aacagcacct
     4621 ctctttattg ataaatcggg taatttttcg ttatcgattg actgatttat tttatggtga
     4681 gatagaaaaa aagtatcctt tttcttacca aatcgctagc gaatgcatac aagcattaga
     4741 agctatcttg caacataaga tctctaaagt agagatcagc tacctaacgt tgtatttgga
     4801 gttagcattt cgatatcaaa aagagcattt ttcctctaaa aaagtagcca ttgttcatac
     4861 gacaggaaaa ggaacagcat taatgatcca aagacaaatc aaaaggatat tggggaggga
     4921 tatacaaata acacatgttt cagaagaaca atatgaaaaa gtagatctaa acaaatattt
     4981 cgctgttttt acaacgattc cgttaaaaaa tgtaaatgaa gagacaccgg tgatccattt
     5041 gactaatctt tttgatgact cttggttaag ggcacaatgg caaaaagcaa aaaaaaagcg
     5101 attagccggg tttcattcta ctgttttttt ctatcaaata tggaaagaaa aaaagacgta
     5161 tcaagaatat ttaaacaaat tagtcgctcc tttgatcaga ggctattatg tggatgaaga
     5221 atttgaaaaa aggatcttga aaagagaata tcagcaaagc acatttgtta acaaagaatt
     5281 tgcttttcct cacacaacca accagctatc tcaacacatt gttttatcag tagggctaat
     5341 aactgatcaa ggtttagcag aaacaggagg aaatggagtt atttttttat ttgccatacc
     5401 tgaagaaatg acggctgaag ttgagaatga attatttgag ctatacgata tcctatttga
     5461 actcataaaa atgggaatag atgagtttat tgaattagca ccgacacaag aatcattttt
     5521 aaaactaatc aaaagtaaag gagagagact tcatgaatga tatgtatcta ttcatagttt
     5581 tcgcagcttc agcttatgtg ctgcaagcag ttatcagttg gaagcaacta aagcatttca
     5641 atcaaacata tagcgaactg cgaagaaaag gaaaagtagc gattggtaaa cgacctggga
     5701 aaatccgttc aggcacgatt gttatgctag ctatagacga tcatgatcaa gttttagaag
     5761 tcagaaaaat gcaaggggtt acatctttgg caaaatttca ttcattacct gtctatgcgg
     5821 gtgaagatat ccattacatc gatcgttacc atccctcagt tcgagcggaa gatcgtttga
     5881 cacaagcagc tttagaaaat gccagagaag tatacttacg aatagaggca ggaaatgaaa
     5941 aaagtgaaca accttcattg ccttttattg ctatgctcaa taattttcgg atatggaaaa
     6001 gtacgatcaa agaaaaaagg agtgacaaac gatggatatc ataacaaaat ttgctgaggg
     6061 atttatgagg ctgttccaaa caggtgcaga aacattcata agctggatga caggaatcgt
     6121 accagttgtc ttgatgctga tggttgcaat gaatacgctg attgcttttt taggtgaaga
     6181 ccgagtaacg aaagtagcca aattatcagc gaaaaatccg cttactcgtt accttgtgtt
     6241 accgttctta tctgctttta tgttgggaaa tcctatgtca tttacaatgg ctcgtttcct
     6301 tccagaatac tacaaaccaa gctattatgc tgctcaagct caattttgtc atacgagcaa
     6361 tggtgtattc ccccatatta atcctggaga attgtttgta tggatgggga ttgctcaagg
     6421 gatcgaaacc ttagggctaa attcgatgga gctggctatc cgatacttgc ttgtgggact
     6481 gctgatgaac tttattggtg gttggataac tgattttact actggatttg tatgcagaca
     6541 gcaaggaatc gttcttagca aaaaagtaga gctttcagtt gattagagaa aggagagttt
     6601 taaatgtatg gtgatattaa gatcgtaaga ggaaacggcg ggtatggagg tcctttgatt
     6661 attaggccga caaaagataa acacaagttc atctatgtca caggtggagg tgagaggcca
     6721 atgatcgtag ataaaataga agaactgaca ggtatggagt ctatcaatgg gttcaaaaca
     6781 tcaatacctg atagtgaaat cgcgcttgca atcgttgact gtggagggac tcttagatgt
     6841 ggaatttatc ctaaaaaagg gataccaacc atcaatatcg tttccacagg aaaaagtggc
     6901 ccattagcac aatatatcac tgaagatatt tatgtttcag cagtagggtt agaacaaata
     6961 cagccactaa tggaaactga tgataacaaa gaaacagtaa atactgcatc tccagataaa
     7021 aagtacaaat atgatacttc taaaaagata accgagcaaa aagcagagca gcaaaactgg
     7081 atagcaaaaa ttggaatggg cgcgggaaaa gtagttgcta cattcaatca atcagcaaga
     7141 gaagcagtag atacgatgat ccggacagtg atccctttta tggctttcgt ttcccttttg
     7201 attggtgtga tacaaggttc tgggatcggt aatgtatttg ctaacattat ggcaccttta
     7261 gcaggaaatg cagttggatt aacaatcatt ggctttattt gttcactgcc atttttatct
     7321 cctttgcttg gtccaggggc agttattagc caagtgattg gaacattgat cggtgtagag
     7381 attgggaaag gaaatattcc tccccaatta gcattaccgg cactatttgc tatcaatact
     7441 caaaatgcat gtgattttat tccagtcggt ctaggtttgg aagaagcaaa agctgagaca
     7501 gtagaagtag gtgtaccatc agttctttat tcaagatttc ttaacggcat cccacgagtt
     7561 atcattgctt gggtagcaag ttttggatta tatagctga
//
LOCUS       DAFENC010000081         7537 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.086, whole genome shotgun sequence.
ACCESSION   DAFENC010000081
VERSION     DAFENC010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7537
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.086"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            107..1248
                     /locus_tag="LP493_002679"
     CDS             join(107..335,335..1248)
                     /locus_tag="LP493_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBL2134782.1"
                     /translation="MAKAKKKFDEDFKKMILDLNQSGQSVEELAAQYGIATQTIYRWK
                     KLHTKNVATGMTEAEILAMKKEMARMQEENTIPKKGFNHIRSKVKMSDVFEFIQSNVH
                     DHDVKQMCTVLEAPKSSYYDWKKKKPSKRQSENKRLNRLISGIYFENKGIYGAPKIHK
                     ILVGRGETLSLKKVQILMRKLGLRSVTLKKYKPGKQAKVKSEGRKNLLNQDFTTTSIN
                     QKWVTDITYIHTLKDGWTYLSTIQDLHTKKVIGWKFGKQMTKELVIETLDNALLNQTP
                     SENLIIHSDLGSQYTSEAYEAKLNELNIRHSFSRKGCPYDNAGIESFHASLKKEEVYP
                     SKAYENFEAAYLALFQYIEGFYNRKRIHSSINYLTPNQMEELALQA"
     gene            1483..1935
                     /locus_tag="LP493_002680"
     CDS             1483..1935
                     /locus_tag="LP493_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134783.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            1949..2638
                     /locus_tag="LP493_002681"
     CDS             1949..2638
                     /locus_tag="LP493_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134784.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            2763..5114
                     /locus_tag="LP493_002682"
     CDS             2763..5114
                     /locus_tag="LP493_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HBL2134785.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            5194..5589
                     /locus_tag="LP493_002683"
     CDS             5194..5589
                     /locus_tag="LP493_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134786.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            5914..6531
                     /locus_tag="LP493_002684"
     CDS             5914..6531
                     /locus_tag="LP493_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2134787.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            6572..6871
                     /locus_tag="LP493_002685"
     CDS             6572..6871
                     /locus_tag="LP493_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HBL2134788.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            6905..7072
                     /locus_tag="LP493_002686"
     CDS             6905..7072
                     /locus_tag="LP493_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBL2134789.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(7117..>7537)
                     /locus_tag="LP493_002687"
     CDS             complement(7117..>7537)
                     /locus_tag="LP493_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2134790.1"
                     /translation="SLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGNELLD
                     TAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQKRLV
                     FKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
BASE COUNT         2594 a         1138 c         1502 g         2303 t
ORIGIN      
        1 attcctcctg ctatcttttt ctattattct atcttatttg atagtagatt taaaactttg
       61 caacagaacc gtagaatcta actactaaga aaaggacgtg tccacgatgg caaaagccaa
      121 gaaaaaattt gatgaagact ttaagaagat gatcttagat ttaaaccagt ctggccaatc
      181 ggtcgaagaa ctggcagcgc aatatggtat cgctacacaa acgatttatc gttggaagaa
      241 gcttcataca aagaatgtag caaccggcat gactgaggca gaaatcctag cgatgaaaaa
      301 ggaaatggcc cgcatgcagg aggaaaacac tatcctaaaa aaggctttaa ccatattcgc
      361 tcaaaagtaa aaatgagtga tgtcttcgaa tttattcaat caaatgttca tgatcatgac
      421 gtaaaacaaa tgtgtaccgt tttggaagca ccgaaatcca gctactatga ctggaagaaa
      481 aagaaacctt ccaagcgcca atcagaaaac aaacgcttaa accgcttgat ttcaggaatc
      541 tactttgaaa acaagggtat ctatggtgcg cctaaaattc ataagattct tgttggccgt
      601 ggcgagacct tgtccttaaa gaaagtacaa atactgatga gaaaattagg cttgcgttca
      661 gtcaccctca agaagtacaa gcctggcaaa caagcgaaag ttaaaagtga aggacgtaaa
      721 aacctgttaa accaagattt taccactacg tcgatcaatc aaaaatgggt gacagatatt
      781 acctatattc ataccctaaa agatggctgg acctacctct ccactattca agacctccac
      841 acaaagaaag tcatcggttg gaagtttggc aagcagatga cgaaagaatt ggttatcgaa
      901 acccttgaca atgcgctctt aaaccaaaca ccctccgaga acttgatcat ccactcagat
      961 ttgggttctc agtacactag cgaagcctat gaggcaaagc tgaatgaatt gaacattcgg
     1021 cactccttca gtcgtaaggg ctgtccctac gataatgccg gtatcgaatc gtttcacgcc
     1081 tcactcaaaa aagaagaagt ctatccatca aaagcgtatg aaaactttga agctgcttat
     1141 ttagcgttat ttcaatacat tgaaggattt tacaatcgca agcgaatcca tagtagtatc
     1201 aactatttaa caccaaatca gatggaggag ttggcattgc aagcttagtt cctagctacc
     1261 acttacattt ttttggcgag atttccacag ggtttcaact tcatcgcttc gatcagcggt
     1321 caaacggttt tggtttgacc gctggtcgaa acgatgagat actcacccgc tggaatctcg
     1381 aaaaaattct cacaaatcgt gtccgaggta ttgactcaaa tccaccaatt atcttatcgt
     1441 agatatatat tataaattta ataagaaagc gaggtgagaa tcgtgaaaaa aacgatacta
     1501 agtatttttt cagtatttac aatattaatt gggggctatt ttcttttgaa tttagattct
     1561 gttaattcaa acgctcaaat aaaagatcaa agagtagctg aacataataa taaaaaaatg
     1621 agtttgacca aaaatatcta ttctatgtca gatgaagaat tgtataaaga atttggtgat
     1681 ttatccgggg aacagttaga agaaagtatt ccaggaatta gtgactcaga taaaattgtt
     1741 gtcttgtctg ctggtgggca attaatggga gatggcaaat ccgaattagt tagttataaa
     1801 caaaatcaca gacagtttat tgatgttaat actgattcca acgctatttc gattaaggat
     1861 ctaaaagagc ttttaaatag taaaagaaat gaattaaagc agataaaaga aactaattca
     1921 gtggaattag agtaaaggaa gattcattat gaaaaagatt tttggtgttt ctgttgggct
     1981 acttatgatg ttaacatttg gaaatgcagt atatgctgct gagaaagaag ttatttcaga
     2041 tccagagcag tacgcctcac gatactttgc tgattttgaa gaagaagata aagtacttgc
     2101 attgccagaa ggtggttttt taaaagggga agctaaaatt gtatctatgg ataatccaga
     2161 tataattcaa ggttcatata attcagaaac tgatcctgct tcagtttcag tgacagaagc
     2221 aaaaaaaatt gttgctgaaa aattcaaaaa tgatattgaa actactccaa ttatgcctcg
     2281 aggagcattt ccacccgatg ttggtactag cggacacctt cttgtactag caggaggagg
     2341 aagctataaa tcacagccat ttagtggtgc gggatggcgt tttggaggta tgggtgtaaa
     2401 accagctgat ggtacaggca actttttacg ttggaaatcc tacattgacg atggaagagt
     2461 aggaaatgta aatcaagcca acgcaactaa atctggttct attcaaggaa tggcattgta
     2521 tgctcgtgaa ggattcaaat actttgcacc aaacgggcct ggttggacaa tgaatatagg
     2581 tatttattac acttataatc ctgttgcagg tacgtattat gttgttcaaa atatttaata
     2641 aaacagcaca aagagatttc tttgtgctgt tttattattt ttagttgttg acaaacacta
     2701 aaatataaaa tataatcaac acataaacga acgtatgttc ggcaagaaag caggggattt
     2761 ttatggatga gatggtttta agtactcaga aatggctaaa caagaaatac agtaatgtta
     2821 cagggtttga taaggttcca gaaaatgggc gaacagggtg gcctacaatc tatggactta
     2881 ttgaaggact acaagtagaa cttggtatta ctaatctagt agctaatttt ggacctacca
     2941 ctgaaaaaat gtacgataat caggttactc ctaaatgggg caaaaatcta cctaaaaata
     3001 ttgtatttct tattcaaggt gccttttggt gtaaggggat taatccaggt ggcttcgatg
     3061 gggtatatac tccatattta gatactgctg taaaagagtt gcagactgat gcagggttta
     3121 atggaagcgc tgtaactgga gttttggatg cgaaatgggc caaagcgtta tttgatatga
     3181 gtgcttttgt tcttgttccc ggcggagata gtaaaattag aaaaatgcag caatggttaa
     3241 atgtaaatta tttagaatac acgggaataa tgccttgtga tggtatttat caaagaaatt
     3301 caaatcaagc attaattttt gcattacaag ctgaactagg atattctccc agtgaagcaa
     3361 cagggtctta tggtaatggg acaactagta aaacttatcc tgtgtctgaa ggtaactcgg
     3421 gaaactatgt aagaataatt caatatggat tatatgttaa tggttatttt gaagacggta
     3481 cattcgatgg tattttcact aaatatatgg gtttagaagt actggcattc cgaaaattta
     3541 tggtattgcc tgaatatact gaaatagcag atgttgttgt aataaaagga ctattgtcta
     3601 gcgctggaga tattagaaga tctgcagatg gcgcagatac ttctacgcaa ttaactagat
     3661 ctcaaatcca aacattggtt gataatgata taaaaatagt tggtagatat cttactggta
     3721 ctgttggaat tggaaaagat gaacgaaata agtatctaac tacagaggaa ttgaataata
     3781 ttttttctaa aaatttatct gtgtttccta tctatcaaga tggaggtgca gcattagctt
     3841 attttactta tgatcgtggc ttatcagatg gtaagaaggc tatagatgca gcaaaaaatc
     3901 taaatatacc attaacaaca gttatttatt ttgctgttga tctagacatg ttaggggaag
     3961 aaattcttgc atatgctgga gaatatttta agggggtatc tgctgtaatg tcatatagcg
     4021 ggtatcaaac gggtgtttac ggaacaagaa atgtttgttc tcaaataatc aataacgggt
     4081 atgcttcgtt tgcatttgtt tcagatatgt cgactggtta tagtgggaat ttaggttttc
     4141 ctatgcctag acaatggtct tttgatcaat ttgttgaatt taccatagga agtggcaacg
     4201 gagctgttgg tatcgattta atcgctacat cgggtagaga tagcggattt aatgagttat
     4261 caaatgatac taataatgat aattacattg ccaaatacaa tcagaaggtt ataaatcaga
     4321 tggtacgtgc gtatcaatat ctatcacaag ctggtcttga taatccttgg aaccctcatt
     4381 tgacatttta tagatatgta aattattctg gtttgtcatg ggacatcatt tcttctcctg
     4441 taacagagca tgatagaaaa atttatgatg aatataggaa taaattaact aatagcgagg
     4501 gcctgtataa ttattttata gatcctaata ctggttcaat aataggtttg cctcacttaa
     4561 ttgtgacgtt acaatcacag atgtttctag ccgacacaat caatgatagt gtttctgact
     4621 ttgcaggttg gttaggagat ttaatgactt gctggggtga agttaagaaa ttaggaatac
     4681 aaatggagca aggtgtattt gcattagtag gtacggctgc aggtggaaca tttagtctag
     4741 aagatttata ccaagatgtt gacgcggtaa atgtttatac cttagcaaaa agaaattctg
     4801 attcaacagc tttatcggct ttaaaaacgt actattgtga taagggtgct attgatagat
     4861 ttaatcaatt tgttaagaac agatttggtt cttcagataa aatcgcttca gtaacaaata
     4921 gtttattaga aaatgacgaa acagttgata tcttaggtgt agggataatt tcatttttca
     4981 ttgataaaat agttaataat tcacttggga cagattttac ttatcttgat tttattggag
     5041 atgaggggaa agttgcaaat ggattttctg aaaaaattat tcaatttcaa gaaaatagaa
     5101 gtaaacttaa ttaagaatcg tttactattt aaacagtgtc cttttccttt ttaaatatat
     5161 acgataaaat aagtatatga attgtaaaag gacatgatga ttatggaaga aatagaatgg
     5221 aataatctga ctcaaaataa taaaaataat tctggatgtg gaattatctt tatgtttgtt
     5281 atagttttgg gaatagtagt acttttaata actgtcaaga tagtagatta ctttgcgaat
     5341 actcctgaag aacaaataca gagaaaactt cctgagtttg aaagagtacc accttatgat
     5401 ccaagagata attcatttca agtaaaaaaa ttaaaagagt ctccaaatga aatgtggttt
     5461 gaagttacag ttgaatcaag cgacttcaaa gaaaaaaaga aagaatacaa ttatattgta
     5521 aaggcaaaag tatcaaaaag atttattttt aaccctaaat tagaaatata tagtgttgta
     5581 atagaataat agtgttaaaa aaattgtaaa agttaaagaa gtcaaattct gatgtgaaaa
     5641 ataaaatata ccatggaaga cataaaagaa aaactggata actagtttat ttaatggcag
     5701 accgttaagg cctgccattt ttatgtattt tagcggaata aatataatca tgcgggagtg
     5761 taaacttact gtttcaaaaa gtatactttt tgacatgcct tgattttctt tgtttatgta
     5821 tggcataata accacataat acaatttgaa acgtttctga tttaatctga ttgttttgaa
     5881 acaattttag tgaaaaaagg gtagataaaa acgatgagaa aattttttta tatccgggtc
     5941 agtagttatg atcaatcgat cgaacgacaa ctgatttccg cgaaggaatt aggaatccct
     6001 gaagaatata tatttgtaga aaaagccagc ggcaaagatt ttaaacgccc tgaatatcaa
     6061 ttaatgaaac ggatgtttcg aaaaggagat ttactctatc tacaatcatt agatagacta
     6121 ggcagaaata aacaaatgat tttagaagaa tggcgagaat taactaagga aaagcagatt
     6181 gatatttctg tgttagacat gcctctgtta gatactgcta gttacaagca actagatggg
     6241 ttagagacgc ttatctctga cttaattctg caattactca gctatatggc cgaagacgag
     6301 cggaaacgaa ttaatagccg gcaaagagaa ggcgtagaag ctgcgaaaca aaagggtgta
     6361 aaattcggca gaaagaaaat tgctttacct cctgaatttc ctgcgatcta ttctgactgg
     6421 aaagcaggaa agataactgc agtctatgct atggatcaat tgggcatgaa acgaaatacc
     6481 ttttatcgac gggtgaaaga atatgaacat accttgcacc acttttcttg atagatataa
     6541 cagctattag acgggaaggg agagtttgaa aatggactta acgaatcaaa gggtcgtttt
     6601 tactggaacg ctgcagcaaa tgacacgaac ccaagccatc ggtttggttc actctttaaa
     6661 cggccattgt caatcaagtg ttacttcaaa aacaaatttc ctggtttgtg gtcagtattc
     6721 taagtcgttg tttgatgatt ctctctatac aaaaaaggaa caaaccgcgc gggacttgat
     6781 tgcgttaggt catgagatta ccattttatc agaagtcgaa ttttatgcgt taattagtca
     6841 acagttgaaa gaatggcaac ggtatttata atcgttagta aaatttacaa ggaggaaaat
     6901 ttttatgaag cgaaaatctt atgatcgttg gggcattgaa ataactagtt ttaatcgaaa
     6961 tattgctttt cacgtggagt gtgactgtgg ggaattagca aaaagtgttt atcaaaaaaa
     7021 ttacttttac tgtcctaaat gccatcgccg atacggggta catggaacat agaaacgaaa
     7081 tagtgcggta gaaaagcgaa tgaatgtagt atatttctac aaatcattcg ctttctttat
     7141 tttataaata gttggtcgag agatcccgtt ttcttttgca atctctgcaa ctggaatgcc
     7201 ttgctttaac atgtccacca cggttttaaa aactaagcgt ttttgcggat ctgttgagtt
     7261 aatagaatac tcgattggtc gtcccttata tcggccggct ttttgagcca ataatactcc
     7321 ttgccgctga cgttcacgaa ttttctcacg ctcgttttgt gcaatataac ttagcagtga
     7381 taaaaacata tcgaacatag cggtatccag gagttcattt ccagtattaa aatctaaaaa
     7441 ctgtgcatct aatattttta acgctacttt tttctgtttc ataaaagcaa ctgtattttt
     7501 tatatcttca taatctcttc ctaaacgatc tagtgat
//
LOCUS       DAFENC010000082         7534 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.087, whole genome shotgun sequence.
ACCESSION   DAFENC010000082
VERSION     DAFENC010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.087"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(552..1898)
                     /gene="gor"
                     /locus_tag="LP493_002688"
     CDS             complement(552..1898)
                     /gene="gor"
                     /locus_tag="LP493_002688"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HBL2134791.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(2032..3285)
                     /locus_tag="LP493_002689"
     CDS             complement(2032..3285)
                     /locus_tag="LP493_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBL2134792.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(3291..4214)
                     /locus_tag="LP493_002690"
     CDS             complement(3291..4214)
                     /locus_tag="LP493_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBL2134793.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(4435..6927)
                     /locus_tag="LP493_002691"
     CDS             complement(4435..6927)
                     /locus_tag="LP493_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBL2134794.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(6934..7401)
                     /locus_tag="LP493_002692"
     CDS             complement(6934..7401)
                     /locus_tag="LP493_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HBL2134795.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
BASE COUNT         2075 a         1638 c         1208 g         2613 t
ORIGIN      
        1 aaatcagtgt tttgtcctga gtattagaga aacaaatgga aaaatagttc ctcatatttt
       61 gccgtttttt gagctaatac cgaaggacag ctgattgaac actatttgtt cggaaaaagt
      121 gactaactat gacacaattt ttttcacagt cccttttttc acttgatttg attcgtacca
      181 gcgaacttga cgagaacttt cttggtttgg taactatatg gtattctttt aacatcctcg
      241 tttgcttctt ctaatttatt tatacaaagt cacacttttt taaacatctg ttcttcgata
      301 catttctatt tcttttaaac atcgatacca atattttgaa cttaagagtg cataccaaat
      361 ggattcattt actcttcgtc agttacgaag ataatcaaaa tctccaactt ccctacttat
      421 ttcgttttga gaattatcga agcaatctta cataaataac taaaaaacaa aaaaccagaa
      481 aatcagtata ctgattttct ggttttacat ggtttgttca ataaaaagct gttggaactg
      541 ttaatattaa attatcgcat cgttacgaat tcttccgctc ctgttggatg gatggctact
      601 gtattgtcaa agtcttcttt agttgcaccc atcttgatag ccacggcaaa accttgcagc
      661 atctcatcga caccaacacc aatagcatgt aagccgacga ttctttcttc ttttccgaca
      721 cagatcaatt tcatttcgca tttttggcga taatcattta atgcaaagta cattggggta
      781 aagcgtgaac gataaacttt caattcattt tcgccatatt tttccaatgc ttcttcttct
      841 gtcaaaccaa ttgttgcaat tggtggatgc gtaaagacga ctgtcggaac aagtttatag
      901 tcaagataag aatctttctt tccattaaat aaacgttctg ataaacgtct accagctgcg
      961 attgcaacag gagtcagatc taatttaccg atcacatcac caacagcaaa aatatgttca
     1021 tccgttgtat tttggtattt atctactttg ataaaccctt ttttgtccaa ttccacattt
     1081 gtattttcca gacctaattt ttcggtattc ggtacacgtc caccggcaaa aagtacacaa
     1141 tcaccagtta aggtttcacc attttcaaat agcaccgtat attcgtcatt gtttttagta
     1201 atttctttag caatatgatg tgcgtaagtt tttattccag cttcttggta catttggatc
     1261 aaattgtccg aaagcatttt atcaaacgtt ctaagtggtc gttcttttcg atatgcccac
     1321 atgacttcac tacctaaacc acgaaataca cctgaaagtt cagccgcaat gtatccagca
     1381 cctaaaacga ttgctctctt aggtaactct gttaattcaa aaaatccatt tgaatcaatt
     1441 gcgtattctc caccaggaat ggtcatttta cttgcacggc ctccagtagc gatcaagatt
     1501 ttaggagcac gataggtttc accgtttact tcgatcgttt gactatcgat aaaagtagcg
     1561 taacctttta tagcctcgac atgattgcta tctaatcctc tttgataagc accgtgtaga
     1621 aaatcaatat atttttctcg tctttctact agaccggcga aatcaacatt ttttaaatct
     1681 gcttggatac cgtaacttga ggcatctcgt tcaattgttt ccaaaatcgt acttgcttgc
     1741 cacataactt ttttaggtac acaaccgacg ttgacacatg ttccgcccaa ttcattcgct
     1801 tcaatcagca aaacttttgc gccatgcatc cctgctctgt ttgctgaagc aataccgcca
     1861 gagccgccac caattacgat gtaatcatat atttgcattt tgttcctcct tattgaagag
     1921 atcaatcaaa acctttattt aacgatcctt tttctacaga aaacaagtgt aacacttttc
     1981 ttgaattttg tatgcgaaga tgcttaaaac agggatatat cagctttttc cttatttacg
     2041 ttttcggatc atatctccag gtttcaccgg ctgtgcgact ggcatagtta aaatcatcat
     2101 tggatttggt gctcggtcaa tggattcgcc ttcttcatta tgcataactt caacggtttg
     2161 actgaaatga ctgaatcctg gaccataaaa ttcgatttca tctcctacag aaaacaagtt
     2221 tctctgacgt atcgtagcaa tctgtgttgc ctcatcataa gataatactt caccgacaaa
     2281 tttatatact gggattttac gacgttcacc gaataattgt tcgttttcag ttggtgtatt
     2341 gtagtaaaaa cctgtagcta attctcgttg tgctactttc cataactcgt cgatccattc
     2401 ttgcttgcag acatagtttt caggatcttc catataactg tctacagccg ctttatagac
     2461 atttgacacc gtagatacat aatggatcga tttcattctt ccttcgatct tgaagctgtc
     2521 tacgccgttt tcaatcaatt ctggaatatg ttcgatcatt gacatatcca ctgcactcat
     2581 cgagaattct tcttccactt cgcctgtatc agttaaactg tttcgttctt gaccaaaagg
     2641 catatcgaac aatccatact tccagcgaca agattgagaa catccgccac ggtttgcatc
     2701 ccgcatcgac atatggttgg acaatgtgca tcgaccagaa taagagatac acatggcacc
     2761 atggataaat gcttcgattt cggtatccgt atttttacga atctctgcca cttcctccat
     2821 tgaaacttca cgagctaaaa cgacacgttc caacccttct tctttccaga attccaatgt
     2881 ctcaaaatta gttgctgaag cttgagtgga taaatggatc ggcagacctg gggcttctgt
     2941 cgcacaaatt tcgatcaaag ctggatcaga aacaatcact gcagaaatac cgacatcacg
     3001 caaactgcgg aaaaattccc ctgctccatc ttcatttcct tcatgggtga ccatattagc
     3061 agcaacgtat accttcgcat catgttcttt tgcaaaagca actccttcag ccatttcttc
     3121 ataagtaaaa ttacctgcac ggcttcttaa accatatgca ttcccgccaa tatatactgc
     3181 atctgctcca taatggatcg cggtttttaa cttttccagt gttcctgctg gcgctaggat
     3241 ttctggtcgt ttcaattttc tttttactgt catttctttc atcatactcc ttatttgata
     3301 gcagaaggat caatataaaa gaatcctgta tctaattcac ggttttcagg atgcaattta
     3361 ctgatttcgc tagtcatttt ttccgctttt tcttgatccc agctaccttc taaaatttgt
     3421 ttttttgctt cggcgaatag tcgagtgatg tttacgaatt tttcgcctgg agtaaataat
     3481 ccgtccaatt tccatgtaca gtaatgatgc tgataaagtt cattcaattc attcgagaga
     3541 ttcagatcat tgctggcaaa aatatgtgtg ccatgactat cttcataaat agaataatgt
     3601 gtctcttctt ttttaggttc cgagataaaa agacctcttt cacgatcttt ttgttcgtct
     3661 tgtttcgtat agttatagta attctgtagc agtggacgtt tggattgatg gatgcatgta
     3721 gcaccataca caagggtttc tacaggaata tcgagttttt cttccatcgc cttcatctct
     3781 tcaaaaggaa cttcacgagc aagtactgct ccaactgcgc cttttttcgc ccagaaattg
     3841 atttgacgtg cgctcgttac taatgtttca gcatcataaa tatacggtat acgcaattca
     3901 ggattttttt tcatcgtata aataatacct gtatcaccaa ctgtgatcac atctacgttt
     3961 atttctttta aaaaagccaa atattcaggt acatttttca ttttttcagg atgaatgatc
     4021 ccatttacag caatattcgc ttttttacca tacttgtgtg ctaattctac caattgtcgc
     4081 tgttcttctc gtgtaaatga agcaggcaga cgcaatccaa attgctcttc accgaaatat
     4141 agtgtatctg cacctgcagc aagcaactgt tctgcttgtt caatagtttc tactgtggtt
     4201 atgagttcga tcataatttt ctcctcctac aacttcataa tagtagcata gctctaaaaa
     4261 ctttccaata cttcttctat ttaaagtcgg atttttgaaa attatttcac aaaaaatcaa
     4321 aataaagttc gatatattct gtccaaatat aaaaagagat tgtgacaaaa atcttgtcac
     4381 aacctcttaa tcaagtctta ctattataaa aattcagcta cacaggccaa gtaactatag
     4441 ggaacctact gtttcctttt taggtccgcg aacattcaat gtgatcttac cttttgaagc
     4501 acctactgtt acgtggtcac ctaaacgaat ttctccgcca agcaaagcct cgctcaatcg
     4561 atcttcaatt tctttttgaa gtgcgcgacg gattggacgt gcaccatatt caggatcaaa
     4621 tccagctttc ccgatcacat cgattgcaga tggtgtgatt ttcacttgaa tatcttgttc
     4681 tttcaatcgt ttgataatcg ctttgctcat gatttggacg attgtatgga tttcatcttt
     4741 actcaatgaa tggaagacga cagtctcatc gattcgattc aagaattcag gtcggaaagc
     4801 tttctttaac tcttctaaga tacgtttttg catggctttg tgatctttag taacatcttg
     4861 gacattgaat ccgacatttt tttcttctcg aatttgtgtc gctccgatat ttgaagtcat
     4921 aatcatgatt gtatttctaa agtccacttt tctaccttta gaatctgtta aatgaccatc
     4981 atccaatact tgcagaagta aattgaaaac gtctggatgt gctttctcca cttcatctaa
     5041 gagaatcact gaatatggtt tttgacgaat tttttctgtc aactgtccac cttcatcata
     5101 ccctacgtat cctggaggag acccgattaa tcggcttgta ctgtattttt ccataaattc
     5161 tgacatatca acacggatca gggcatcttc acttccaaac atgacttctg aaagtgcttt
     5221 ggccaattct gtttttccga caccagttgg tccaaggaac atgaatgaac caattggacg
     5281 atcaggatct ttcaatccgc ttcgtgcacg gcggatcgca cgtgaaactg ctttgacagc
     5341 ctcatcttga ccaacgacac gttcatgcag aagtccttcc agttctaaca agcgttcgct
     5401 ttcttttttc tccaactgct gtagagggac accagtccac tccgatacaa ctgtagcaac
     5461 atcttcttct gttacacgat cagaataacc ttgctcctgt tttgcttcaa ttgcagaaac
     5521 tttttgcagc tttttacgta gtgctttttc ttgtctgcgt aattgagcag cattttcaaa
     5581 gtcttgtttt tggatcgctg cttccttttc ttgtactagt tcatcgattt ctagtttgat
     5641 cacagttgat tttgttaagt gatcggtttg atccaaacgg actttcgctg ctgattcatc
     5701 gatcaaatca attgctttat cgggtagttg acgagaagtg atataacgaa cagaaagatt
     5761 gactgctgct cgtacagctt catctgtgat ctccactcca tggtgctctt catatcttgt
     5821 acgtaatcct tgaagaatca cttctgcttc ttcaggagtt ggctcatcta cttgaatgcg
     5881 agcaaaacgt cgctctaatg cagaatcttt ttcgatatat ttttgatatt catctagggt
     5941 cgttgctccg atcgtttgta attctcctcg agctaacgcc ggtttcaaga tattcgaagc
     6001 atcaattgct ccttctgctc cacctgcacc aattaaggta tgcaattcat caatgaataa
     6061 gattacttga ccatcattat agatttcgtc gatgaccttt ttcattcgat cttcaaattc
     6121 accgcgatat ttcgtaccag caaccaaaga tcccatatca agcatcatca ggcgcttttc
     6181 ttgcatgtct tctggcactt cacctaaaat gattttttga gctaaccctt cagcaatggc
     6241 tgttttgcct acaccaggtt cacccaccag tacagggtta ttctttgtcc gtcggctaag
     6301 aatctggata agccgtttca cttctctcga acgaccaaca actgggtcca gcttgttttc
     6361 ttttgctaat ttcgtcaaat cacgtgctaa tgaatctagc gtaggtgttc cttgcggtgt
     6421 ttgccgttta tcttgtacat ttacatttct acgacgattc attccttttc cagcagaatc
     6481 accagctagc cccatttttt gtttcagaac ttgacgggct tttgaaaggc tgatacctaa
     6541 gttgatcatg attcgagtag ccatgatact ttcatctttt aataagctca tcaaaatatg
     6601 ttctgttcca actttttgag aaccagtttt cttcacttcg ctgctagcta aagcaaaaac
     6661 ttgtttcatt cttggtgaat atggaagaaa gactccttta gggtaagaac ggataccacc
     6721 ataaccaatc agatgttcaa tttcttcata aatttccgtt tcattcaaat ccatttcacg
     6781 taatactttt ccagcaattc cattttgctc gaccactaag gctagtaaaa catgttctga
     6841 actaactgat tgatgtttca accgttttgc ttcttcttgt gcaatttcta atactgcttg
     6901 ggctctttca gtaaaaagtt cttccatcta atctcacttc ccatcttcat aacttaaacg
     6961 ttccagaaat gctcggagaa tccgagcacg tgtatgatct tcatattcat tgaaattcaa
     7021 tgtgtttttt gcaattgcac tcaacatcaa gtttccttct ttttttgtaa ttatttggtc
     7081 ttcataaagt ttttgaataa tagcaaaagc atttttctca ctgattgtat catcaaataa
     7141 ctgatttatc tgctcaagta attgtttttt atctgaaatc cttacttttg caattcgtat
     7201 ataaccacca ccaccacgtt tgctttctac tagataacca cgttggatgg taaaacgggt
     7261 attaatcaca tagttgattt gtgaaggaac acagttaaag aggtctgcca tttcaatcct
     7321 tcgaatctcg atcatttcac tattttccag aattttcttt atatatgatt caattaaatc
     7381 cgaggtattc tgatgtgcca tcttattcat tccctttgac taatattgac cttaattata
     7441 acgaatttga taatagaaag aaagaagaac gctttttgtt aaataaatcc tttagaatca
     7501 acaaaaaaaa atacggaata tactattccg tatc
//
LOCUS       DAFENC010000083         7397 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.088, whole genome shotgun sequence.
ACCESSION   DAFENC010000083
VERSION     DAFENC010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7397
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.088"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(204..1652)
                     /gene="cls"
                     /locus_tag="LP493_002693"
     CDS             complement(204..1652)
                     /gene="cls"
                     /locus_tag="LP493_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBL2134796.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGEIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHTTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            complement(1804..2697)
                     /locus_tag="LP493_002694"
     CDS             complement(1804..2697)
                     /locus_tag="LP493_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2134797.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            complement(2681..3367)
                     /gene="ftsE"
                     /locus_tag="LP493_002695"
     CDS             complement(2681..3367)
                     /gene="ftsE"
                     /locus_tag="LP493_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HBL2134798.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            complement(3472..4573)
                     /gene="prfB"
                     /locus_tag="LP493_002696"
     CDS             complement(join(3472..4500,4502..4573))
                     /gene="prfB"
                     /locus_tag="LP493_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HBL2134799.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            complement(4699..7233)
                     /gene="secA"
                     /locus_tag="LP493_002697"
     CDS             complement(4699..7233)
                     /gene="secA"
                     /locus_tag="LP493_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBL2134800.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
BASE COUNT         1982 a         1639 c         1289 g         2487 t
ORIGIN      
        1 gctatactgg ctttgaaatg tgtctctttt aatagcatat attagcttat ttcttgcttt
       61 ccccaaaaaa caagagatac cccaaagtta atttcgctca tgcgagacgc tttctccatt
      121 tctgacgtac tctcagaaat ggccccgtta aaaaaggaca cgagatctcc atctgttgat
      181 ggttctcatg tcctttttat gttttaaagg agcggcgaaa tcaatcttgc taatccttct
      241 ttcatcttga tgattattcc tcggttttca tacatttctt ttgtgagatg cgtagaaatt
      301 ttcgagtctt caaaaaaagc ttttcttaca cgtgaagcca ttcgttcatc ataaaccagt
      361 gtattgacct caaagtccaa gcgaaatgaa cgaacatcga tatttgctga gccaactgaa
      421 acaatgccac catcgataat catcgtcttt gcatgaataa atccattctc atatgtttcg
      481 atccttgctc catactcgat cagctctgca gcgaaagaat acgttgccca gtaaacgaga
      541 agatgatctg gtttgttagg tatttggata tgaactttta cgcctgaaag aagagccaac
      601 ttcagtgctt catgaatcga tccatccggt atgtaataag gcgtttggat caatatctcc
      661 cgtttggcta acgaaatcat tttcaaataa gtcattttga tttgttcatg ttcggtatct
      721 ggtccgcttg tcacgatttg aacagctata tcaccagtag tgtgaatgga cggaaaaaat
      781 ttgggagaat agcctacttc ttttgtatgc tgagaattcc agtccatcaa aaaacggttt
      841 tgcaaggtat acaccgcttc tccgtaaata cgcaaatgat tgtctcgcca ataaccaaat
      901 ttctttacca atcctagata ttcatttcca acattgaacc cacctgtata tccgatttcc
      961 ccatcaataa ctacgatttt acgatgattg cgataattga tccgaggatt aatatacgga
     1021 acaaatagag gaaagaaaaa tgcgacttct ccgcctgctt ttttcaaatt ctgaaaaaag
     1081 ctggaagaaa cttgtgtgga accccatgca tcaagaagga ctctgacttt tacccctcgt
     1141 cttgccgcct ctgtcaatgc atctcgaact tcttcaccta atgcatcact gcgataaata
     1201 taatactgga agtggatatg gtcttctgcc tgcttgatat cttcaatcag cgcatcgaat
     1261 ttttcacgac catctgtaaa taaagtgatt tcatttttag tcgtatagag cgtactttca
     1321 aataccgtga gcatatagat caattgtttc acatctactt gtccagtagg cggatgagga
     1381 taaagccctc gcatcaatgc ctgtttgtct tcttcaattt ccaggttctt accgattttc
     1441 ccttggatct tcaaatcaaa gattttctct ttggaaatcc ctcttcctaa aaaaatatat
     1501 aaaataaatc ctacaactgg aatgaacatc aaaacgagca gccatgccca tgtttgagca
     1561 gtttcctttc tttctcgaaa aacgatgata aaggaaagca aaatattcat aatcaaaagg
     1621 atcgtaaaaa aattgtcaac gataattttc acggcttcac ctcttcttct accaacttaa
     1681 gaatacccaa gttgtttttt aaagtaaagg gaaaaaagcc gcttccttct attctcctag
     1741 ccaataaaaa aagaaagctg gaacgaaact gtccaacttt ctcattttat ttatattgtg
     1801 gtattagaat ttcaagaaac gtctcataga aatgatcgag ccaagtgaac caatgatcac
     1861 accaatgccg accattaaaa gattgatttt ccaaacgata ttttgtggat gaatcaatga
     1921 ataatgggaa cgtaataatg atggattgat caattggaaa aaccatgcat aaccaaatgt
     1981 gatgatcaaa attggaagaa ttgcaccgat cagaccgatc cagccacctt caaggaaaaa
     2041 cggccagcga atatatccat tttttgcacc gactaaacgc atgatttgaa tttcacgctg
     2101 tctagacaaa atcgtgatcc gaatcgtgtt cgaaatgaga aacatcgcta cgaacagcag
     2161 caatgccgct gcaactaatc cccatgtccg aactgcacca gcgatttgga aaatccgatc
     2221 tgaggaagct ccaccgtaat cagaacgaga aacattcttc aaatctgctg cttcttctgc
     2281 tacttgtttt gtataagaag gatcagtagc acttactaca tacacatcat ataacgggtt
     2341 attgtcacct tcaaacaatt tccaggaatc acccatttcg ttttggattt ttttcaattc
     2401 ctgttctttg cttgaaaatt caactttttt aacatgatct aagtcattca attctttttc
     2461 tagctttttc atctcttcgt cttttgtacc gatatctacg aatacagata catcaacgtt
     2521 tccttctata tcctgagcta atttagttgc attcatgata actgccatga atacaccgac
     2581 taaagtcaac gtgatcgtta ccgcactgac tgaagcaact gtcatccagc cgttacgttt
     2641 caaactcttg atactttcta ataaatggcg gaaaaaggtt ctaatcatcg tatccatatt
     2701 ccccttccgc ttgatctcga ataatgcggc cgttttcgat agcaattact cggtgccgaa
     2761 tcgtatttac gatcgtactg ttatgtgtag ccatcacgac agtagttcct tgggcattga
     2821 tccgatctaa taatttcatg atttcccatg agttttctgg atccagattt cctgtcggtt
     2881 catccgcgat aagtacttta ggcgtattca cgattgcccg agcaatagag acacgttgct
     2941 gttccccacc ggataattcg ctaggaaaga ctcgaacttt gtgtttcaaa ccaacaaggt
     3001 ccagcacttc cattactcgt tttttgatat ctcgaggttt tctgccgata acttgcatag
     3061 cgtacgcaac attttcatat actgtttttc ttggtaataa tttatagtct tggaacacca
     3121 cgccgatttc tctgcgtaga taaggaactt cgcggttttt gattgctatt agatcatgac
     3181 ctgcgacgtt caaagttcct tttgaagctt tttcttctcg atacatcaat ttgatgaatg
     3241 tagatttacc ggctccagac ggaccaacca catagacaaa ctctccttgt tcgatgacaa
     3301 tcgagagatt gcggatagcg gtcgtaccat ttgagtactt cttcattaca tccttcattt
     3361 caatcatggc gttctctcca tatctttttc agtctttagc tattatagca tggcaatgtt
     3421 tcaacatgct tgcaaaatct tacaatttta tttcaattta acaatgggtt cttattgtag
     3481 atgcattttt aaatagccgt caataaataa atcaaggtca ccgtccataa ctgcttggac
     3541 atttcctgtc tctacgtttg tccgatggtc ttttaccata gaatagggat ggaaaacata
     3601 agaacggatc tgtgaacccc agccgatttc tttttgttct cctcgaagtg cagctgcttc
     3661 ttgttctttc ttttccactt ctaattgata aagcttagct tttaacatcc ccatcgcttg
     3721 ctcacggttt ttcaattgtg agcgttgtgc ctgactagct actactgttc ctgtaggcaa
     3781 gtgagtgatc cgtacagcag attctgtttt attgatgtgc tgaccacctg caccacttgc
     3841 tcggtacgta tcgattttca aatcatctgg attgatttct atatcgatcg tttcatcaag
     3901 ctctggcatc acatctaccg aacaaaaaga agtatgacgt cgtttcgctg agtcaaaagg
     3961 cgaaatccgt acaaggcgat gaacaccttt ttctgatttt agataaccaa aagcgttatg
     4021 tcctttaatc agcagggtca cactcttgat ccctgcttca tcacctgctt gataatctag
     4081 tgtttctact tgatagccat gctgctctgc ccaacgtgta tacatacgta aaagcatgct
     4141 gccccagtct tgggactccg ttccgccagc ccctggatgc aattcgacga tcgcattgtt
     4201 tcgatcataa ggtccgtcta acagcataga taattcatac gtcttcattt tttcatctaa
     4261 tgcattgata cgtgtttctg cttcttcttg cattgctgca tcaggttctt cttgcagcat
     4321 ctccaccatc aattcgattt cttctagttc ttcggcaaga gaatggaatt ggtcataggt
     4381 ttctttatta gcgttatttt cgctgatcac tttttgtgcg gcttcgctgt catcccaaaa
     4441 accaggttca gccatttttg cttctgcttc cgcgatgtct tcttccagct gatctaagtc
     4501 aaagagacct cctgaaactt gtgacctttt cctgcatttc tgtcaggaga tttcgaattt
     4561 cggatatttc catgtttttt ccttctttca ctatactttt ttcattatat ctagtctaac
     4621 agaatcagca aataacagaa agaaggtgag acgaattctt aaaaaaagaa tttgtctcac
     4681 caatcctgct gtcagaaatt agtttgcatt ttttccatga cagttcttat attttttccc
     4741 gcttccacaa ggacaaggat catttcttcc gaccttattc acatggattg gctgtttttt
     4801 cgcgctagta ttactatttt ctttggcatc tccgtcttct gagtgagaag ctgttccttg
     4861 agaaacctgt tcacgctgta cgttttgacg gatctcagct ttcataaaga ttcgagtgac
     4921 ttcatactcg atggcgccta ccatatcttc aaacatctta tagccttctg tttgatattc
     4981 gactaatgga ttgttctgtc cataagcacg taagccgatt gactgacgta attgatccat
     5041 tgcatcaata tggtctgtcc atttagagtc cacaacacgc aagatcacga ctttttcaaa
     5101 ttccaacagt tgctctggac catttagttg agccgctttg gtattaaata cttcttgtgc
     5161 tcgttcgttt agatactctt tgatctcctg agctgttttt ccttcgatat ctgcaagagt
     5221 aatgctatct tcatggacaa gagtactgcc ggcaaaatcg atgatacttt ccaaattcca
     5281 attttctttc tctaattgtg tatgcgcatc tactacacga ctgattgtcc gtttgaccat
     5341 gttcattagt ggcttggata agcttttttc ttccatgatt acttcttgtc gctgtttata
     5401 gattacttca cgttgttcac gcatcacatc atcgtattgt aagacgtttt tacgtgtgtc
     5461 atagttattt ccttctacac gtttttgtgc agattctact tgtttcgtca gcatcttgct
     5521 ttggataaca gcatcttcct caccgatctt catccgatct aagaaagctt tgattcgttc
     5581 tgaaccgaat cgtttcatca aatcatcttc caatgacaag tagaactgtg acataccagg
     5641 gtctccttga cgtcctgcac gtcctcgaag ctggttatcg atacgacgag attcatgtcg
     5701 ttctgtcccg ataactgcta gaccaccaag ttctcttacc ccaagtccta acttgatatc
     5761 tgttccccga ccagccatgt tggtagcaat cgtcacagca cctttttgac cagcattcat
     5821 gatgatctct gcttctttaa agtgattttt cgcattcagc acttcatgag gaatacgttc
     5881 ttgattcagc atatctgata ataactcaga tgtttcaacc gcaacagttc cgactaacac
     5941 aggttgacct ttgcggtagc gatctttgat atcttgcacg acagcgtgga acttgctttg
     6001 taatgttggg taaagcaaat ctggacgatc atcacggata accggacgat ttgtcggaat
     6061 ctggtatact tggatgttat aaatttctct gaattcttct tcttctgttt tagctgtacc
     6121 agtcattccc gcaagtttct tgtacatacg gaaatagttc tggaaagtga tcgtcgccat
     6181 ggttttcgtt tcgtcttcga tctctacgcc ttctttagct tcgattgctt ggtgaagtcc
     6241 atctgaataa cggcgtccat ccatgatccg accagtgaac tggtcaacaa tcagtacttt
     6301 tccgtcttgg acaacataat cgatatctaa aagcatgata tagttggctc tcaatgcttg
     6361 atccaagtga tgggtcaatg cagtattttc aatgtcgtat aagttatcca aaccgaatgt
     6421 ttcttctgct ttttcgatcc ctgcttcggt taaactgatt gtttttgatt gtacatcgat
     6481 tttataatct tcttcttctt tcaaacgttt cacgaagttg tctgctcttg tatataaagc
     6541 tgtggatttt tctgcttgcc ctgaaatgat cagcggcgtt ctcgcttcat caatcaagat
     6601 tgagtcaact tcatcgacaa tggcataatt cagcggacgt tgtaccattt gatggcggta
     6661 aacgaccata ttgtctctca agtagtcaaa tcctaattca ttattcgtac tataagtgat
     6721 atcacaatta taagcctcgc gtttttcatc cgaagatttt gagttgatat tcaaccccac
     6781 tgttaatcct aagaaattat aaagttcgcc catttccgtc gagtcacggg ttgctaaata
     6841 ttcattgacg gtaactacgt gtaccccttc gccagtcaga gcatttagat atactggcat
     6901 cgttgcggtc aaggttttac cttcaccagt acgcatttca gggatatttc catcgtgaag
     6961 cacgattcca cccatcaatt gtacgtggta tggatataaa cctaatacac gttttgctgc
     7021 ttctcggacg actgcaaaag cttccggaag taattgatct aatgtttctc ctttttggta
     7081 tctgcccttg aattcagcag tttttgcctg taattgttca tcagttaatg ctgccatttg
     7141 gtcagcgtat gcttcaactt tttttgcaat gctatctaaa cgttttagtt ctttcttatc
     7201 gttttcgata agtgaacgaa tcaaattggc catgcgttgt gtaatctcct tttccttctg
     7261 tgtattatcc agactatgta gactttactt ttcattttat cattagttat agataattga
     7321 aatatcttaa gcgtattaaa gtaagaactt cataatttat tcatatttca tctaaaagag
     7381 gaggaaactc aaaaaaa
//
LOCUS       DAFENC010000084         6984 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.089, whole genome shotgun sequence.
ACCESSION   DAFENC010000084
VERSION     DAFENC010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6984
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.089"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..227
                     /locus_tag="LP493_002698"
     CDS             <1..227
                     /locus_tag="LP493_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HBL2134801.1"
                     /translation="KTTEFDILHALMSTPNKVFSRSDLIEKVKGIEFDGLDRSIDSHI
                     KNLRHKIENDAKSPMYILTVHGTGYRFGGH"
     gene            227..574
                     /locus_tag="LP493_002699"
     CDS             227..574
                     /locus_tag="LP493_002699"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134802.1"
                     /translation="MRKRTIKTQLAVSFLAIATLIIGSISLVALSLMNNHFSKYVEER
                     QEDLLNQYVYTIDLLWLNSGETWNSEELAALSEKVLENNIYFSIEDEQGNMVWELTGK
                     DLKSAQEKLKKMH"
     gene            571..1620
                     /locus_tag="LP493_002700"
     CDS             571..1620
                     /locus_tag="LP493_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL2134803.1"
                     /translation="MKVSEKNSVKLDETIEVKKKLINDGNEFGKVTFYYFGPFAYTEH
                     DALFISSMKQSLMYVAIAALLVSFILASWISARLGLPLKHVSDFTHKLTRGEYADKIP
                     QETSIIEINSLIDSLNDLSNQLEKQHGLRKRLTTDISHELRTPLATLKGNVEGMIDGV
                     WKITPERLQSCYDEIDRLTRLIGNIEIINKIEAKYDHLNKTEFNIYKLIESVIENFAS
                     KIESKNLHVEIQGDNINISADKDKMNQVVINLLNNAIKFTQKEGTIKFSISKNKDHVL
                     LIVEDNGIGIEKDQQLHIFDRFYMADPSRSRALGGQGIGLAIVKSVIEAHKGSITVKS
                     KLGLGTKFVIKLPFQ"
     gene            1635..1841
                     /locus_tag="LP493_002701"
     CDS             1635..1841
                     /locus_tag="LP493_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134804.1"
                     /translation="MFQKQIKIAKLVCECWAKKIFFQLISIDSVEKVHLDILSNSVVI
                     FSKKDLSIATIKKEVFGLQIYEMT"
     gene            1862..2458
                     /locus_tag="LP493_002702"
     CDS             1862..2458
                     /locus_tag="LP493_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdhK family protein"
                     /protein_id="HBL2134805.1"
                     /translation="MKTVKKMTKLVFASLGIIVFLGACSNQSESNNSNSTNEESTSTA
                     SSEMNSMEGMNHEGMVPSSMKDAANPKFPVGSNVILLGDHMEGMKGANAQVVGAFDTT
                     MYEVSYEPKTGGPMVNNHRWVVQEELKDTETVANEGDTVILNADHMDGMMGAEAKVDK
                     SITGTVYVVNYTPTDGQEEVKNHMWVTEDEMEYDENNE"
     gene            3410..4009
                     /locus_tag="LP493_002703"
     CDS             3410..4009
                     /locus_tag="LP493_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL2134806.1"
                     /translation="MKSVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLRDVLEISRGRVIVKERLAMKEQKTAKHNSVFISNKLRKVILDYVQSEFPEQ
                     LQAQDFSKYLFPSRKGADTPLTRQSLWRIIHEAGTAVGLKEIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            4058..4774
                     /locus_tag="LP493_002704"
     CDS             4058..4774
                     /locus_tag="LP493_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBL2134807.1"
                     /translation="MNEEKQPNFPDKYHLSRKESVYLLKKNIVELVYNAGKFEGLNTT
                     LLQTEGIIKYNRANNVAVDDVLTVVNLKRGFEMLLNDVQEPLLETSKRINRIVAAEDA
                     LFPGEIRTGGVELSTIQGRYVPPMLTEDEVNNQYGEIMNQEISDTEKALRLFLFISKN
                     QIFWNGNVGTALLIANKIMFSNGLGLLSIPENVFMKFNELLSKYCNSNLLVNESNIIS
                     FLYEQCIFGINYLKIIQHTI"
     gene            4788..5567
                     /locus_tag="LP493_002705"
     CDS             4788..5567
                     /locus_tag="LP493_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002396205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HBL2134808.1"
                     /translation="MMTIDEAKQLATYFSVGSAGYILDFTNVTWNIFTKKIVGIEIQN
                     HYGGSKGVSFQKFLLDDQFDDSLKNRLIQSLKGIMDRDKKYESTEMNPIVQLLFEEVF
                     KEDTSTALRKMKFSSEIDLLYIRQLPIRIQTDIKNKDFDSVLTKANTLIDEVLKFIIE
                     NTEGPSVNINLFKSKELRKEVFGRLNIKTEKDMDNRIKALVGALNTLSDKILEMRNSQ
                     GDAHAHGSNRIVIKEEEAILVANSSMVLCEYVFTKYKGLNR"
     gene            5650..6006
                     /locus_tag="LP493_002706"
     CDS             5650..6006
                     /locus_tag="LP493_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBL2134809.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVDNGRYVITHGFTKKTEKTPITE
                     LKHAKELREEWFTNDD"
     gene            5996..6262
                     /locus_tag="LP493_002707"
     CDS             5996..6262
                     /locus_tag="LP493_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2134810.1"
                     /translation="MMIKKLIEEKKKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            6421..6699
                     /locus_tag="LP493_002708"
     CDS             6421..6699
                     /locus_tag="LP493_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134811.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYVNNSSGQSVINKQIVENRVLLQSFKNKISFCIISSF"
     gene            complement(6696..>6984)
                     /locus_tag="LP493_002709"
     CDS             complement(6696..>6984)
                     /locus_tag="LP493_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBL2134812.1"
                     /translation="TDKAPSLGSAFRKLQSVGLYTKTEHRTVKYLNNLIEQDHRSIKR
                     RHKLYQSLRTASTTIKGMETIRGIYKKSRKEGTLFGFSVCTEIRILLGIPA"
BASE COUNT         2558 a          980 c         1355 g         2091 t
ORIGIN      
        1 ttaaaacaac tgaatttgat attctacacg ctctaatgtc cacacctaat aaagtctttt
       61 ctcgtagtga tttgatagag aaagttaagg gaatagaatt tgatggacta gataggagca
      121 tcgattctca tataaaaaac ttaagacata aaattgagaa tgatgctaaa tcacctatgt
      181 atattttgac agtccatggt acaggataca gatttggtgg ccactaatga gaaaaagaac
      241 gataaaaact caattagctg tttccttttt agcaatcgca acattaataa taggatcgat
      301 tagtttagtc gcattaagtt tgatgaacaa tcattttagt aaatacgtgg aagagcggca
      361 agaagatttg ttgaatcagt atgtatatac aattgattta ttgtggttaa atagtgggga
      421 aacatggaat agtgaagaac ttgcagcact atctgagaaa gtattagaga ataatattta
      481 tttttctata gaagacgaac aaggcaacat ggtttgggaa cttactggaa aagatttgaa
      541 gtcagcacag gagaaactga aaaaaatgca ttgaaagttt ctgagaaaaa cagtgtgaaa
      601 ctagacgaaa caatagaagt gaaaaagaag ttaattaatg atggaaacga gtttggaaaa
      661 gtaacgtttt attatttcgg accttttgct tatacagagc acgatgcctt gtttatctcc
      721 agtatgaaac aaagtttaat gtatgttgca attgcagctc ttcttgtatc attcatactt
      781 gcttcgtgga tctctgctag attaggattg ccactaaagc atgtaagcga ttttacacat
      841 aaattaactc gtggggaata tgctgataaa atcccacaag aaacttcaat tattgaaata
      901 aattccttaa ttgattccct aaatgattta agtaatcagt tggagaaaca gcatgggctt
      961 cgaaaaagat taactaccga tatttcacat gaattaagaa ctccattagc tacgcttaaa
     1021 ggcaatgtgg aaggaatgat tgacggagtc tggaaaataa ctcccgagcg cctacaatct
     1081 tgttatgacg aaatagatcg tctaactcgt ttaattggaa atatagaaat aatcaacaaa
     1141 attgaagcaa aatatgatca tttaaataaa actgagttta acatatataa gttgattgaa
     1201 tccgttattg aaaatttcgc cagcaaaatt gagtcaaaaa accttcatgt tgaaatccaa
     1261 ggggataaca tcaatatatc tgcagataaa gataaaatga accaagttgt tatcaatctt
     1321 ttgaataatg ctattaaatt tacgcaaaag gagggaacca ttaagttttc tataagtaaa
     1381 aataaagacc atgttctttt aattgttgaa gacaacggca tcggtataga aaaagatcag
     1441 caacttcata tttttgatag attttatatg gctgacccct ccagaagtag agctttaggg
     1501 gggcaaggta tcggattagc tattgtaaag agcgttattg aagcgcataa aggtagtata
     1561 actgtaaaaa gtaaattagg tctaggaact aaatttgtta taaagttacc atttcaataa
     1621 aggaggagag ttatttgttt caaaaacaga taaaaattgc taaactagta tgtgaatgtt
     1681 gggcaaaaaa aatatttttt caactgattt cgatagatag tgtcgaaaaa gttcatttag
     1741 atatcttatc aaattctgta gtaatctttt ctaagaagga cttatcaata gctacaatta
     1801 aaaaagaagt ttttggatta caaatttatg agatgaccta aatgtgatta attaaaggag
     1861 gatgaagaca gtgaaaaaga tgacaaaatt agtatttgca agtcttggaa ttattgtatt
     1921 tttaggagcg tgtagcaatc aaagtgaatc gaataattct aatagcacaa acgaggaatc
     1981 gacttctaca gcgtctagtg aaatgaatag tatggaggga atgaatcacg aaggtatggt
     2041 tccttcttca atgaaagatg ctgcgaaccc taaattcccg gtgggaagta atgttatact
     2101 gctaggcgat catatggaag ggatgaaagg tgcaaatgct caagttgtag gggcctttga
     2161 tactacaatg tatgaagtaa gctatgagcc aaaaactggg ggaccaatgg ttaacaatca
     2221 tcgatgggta gtacaagaag agttaaaaga tactgagact gtagcaaatg agggcgatac
     2281 tgttatcttg aatgccgatc acatggatgg gatgatggga gctgaagcaa aagtagataa
     2341 atctattaca ggaactgttt acgttgttaa ttacactcca accgatggtc aagaagaagt
     2401 taagaatcat atgtgggtaa ctgaagatga gatggaatat gacgaaaata atgagtaatt
     2461 ttatatacta aaccaacaag ctggtacatg gtcttcgtat tctcaacatg aggaatatga
     2521 gctctttgtt aataaggact gatgagttgt gcaaaatcaa atctgggtca gaacgaacct
     2581 cattctggct cagatttttg gctcttcgac atttagtgct ggtagagaga caactgaaaa
     2641 tttagtcata accagttagg cagagtgctt aactggtttt tgttcgcatt tattattctt
     2701 ttgatattgg ctgcttgccc ttcaatttta tttggtttct taatcaactc ttcatataac
     2761 cccaaatcat atattaatga ggtgcctcct attcctataa atctatctct tctttaatag
     2821 tatgagaaaa gtctactctt gtagatttaa attgtcaaca aaaaatttac agatgtaaat
     2881 gataagttga atagagaaag ataaattatt tttttggtat tcatataagg ttaattatgt
     2941 attatcacaa aatgattgtt gtcgaataac taaaagtgtc aaaacaatga tgaaatcatt
     3001 tagttcttat aaattagaca agagaaaata aatattccat atctacttta ttggatccat
     3061 aacatgacta aattctgaat actttttaaa gcttatcatt tggtaaaact gaatataagt
     3121 taattatata gactgaaaat tttgaatttt cagaatagaa taacttaaaa gtactgacaa
     3181 attttttaaa ggggcaatat taatgttctg agataatcaa atcttaccga aaatatcaaa
     3241 agtccaatgt gacacaattg gattttgtca cattcgttaa aatcgctcca tccttagagg
     3301 ctctaatagg aaatcacttt tcttttagcg ccttttttct atagcttgtt taaatgtgac
     3361 ttattatctg ttataatcgt attaagtaac atttgagagg tgtctaaaaa tgaaaagcgt
     3421 ggaaccgatt cgcgacaaaa aaaagatcga tgccatgaag gccattttgg cttccggaaa
     3481 atatgggcaa cgaaatttgg tgcttttttc gatcgggatc aatacagcct atcgaatctc
     3541 cgatttaaga cagttaaaat taagggatgt gctagaaatt tcccgtgggc gggtgatcgt
     3601 caaagaacgt ctggccatga aggaacaaaa aacggccaaa cacaattcgg tcttcatttc
     3661 gaacaaattg cgaaaagtga ttcttgatta tgttcaatcc gaatttcctg agcagttgca
     3721 agcacaagac ttcagcaagt atttgtttcc aagtcgaaaa ggagcagata cgcctttgac
     3781 ccgacaaagc ctttggcgga tcattcatga agcaggaact gcagttgggt taaaagaaat
     3841 tggtccccat tcgatgcgta agacctttgg ctatttttta tacaagcaag gaaccaaaac
     3901 agagatcatt cagtcgctgc taaaccattc ttcacaacgg gagaccttac gctatattgg
     3961 aatcacccag gaagacaaag atactgcagt aaagagtttg gatttatgac agaataatgc
     4021 cctatataat agaaggaaaa attcaagagg tgagaaaatg aacgaagaaa agcagcctaa
     4081 ctttcctgat aaatatcact tatctcgcaa agagtctgtg tatttattga agaaaaacat
     4141 tgtagaactg gtgtataatg cggggaaatt tgaagggtta aatacaacgt tgttacaaac
     4201 agaagggatt attaagtata atcgggccaa caacgtggct gtagatgatg tcctgaccgt
     4261 cgttaactta aaaagaggct ttgaaatgct tttaaatgac gtacaggagc ccctgttaga
     4321 gacaagtaag cggattaatc ggatcgttgc agcagaggat gcgctttttc ccggtgaaat
     4381 acgaaccggt ggggtagaat tatcgacgat tcaaggaaga tatgtgccac caatgttaac
     4441 tgaagacgag gtaaacaatc aatatggtga gataatgaat caagagatat cagatacgga
     4501 aaaagccctg cgactgtttc tattcatttc gaaaaatcaa atattctgga atggtaatgt
     4561 gggtacagcc ttgttgattg cgaataagat tatgtttagc aacggtttag gactattatc
     4621 aatacccgaa aatgtattta tgaaatttaa cgaactttta tcaaagtatt gcaacagtaa
     4681 tctattagtc aatgagtcaa atattatatc atttttatat gaacagtgta tctttggtat
     4741 taattatttg aaaataatcc aacatacaat ttaagaggta taagtaaatg atgactatag
     4801 acgaagcaaa acaattagca acttattttt cagttggttc agcgggatat attttagact
     4861 ttactaatgt aacgtggaac atatttacaa agaaaatcgt agggattgaa atacaaaatc
     4921 attatggggg ctcaaaggga gtatcctttc aaaagtttct gcttgacgat caatttgatg
     4981 attcgttaaa gaatcggtta atccaatctt taaaaggtat tatggatcga gataaaaaat
     5041 atgaatctac tgaaatgaat cccatagttc agttgctttt tgaggaagta tttaaagaag
     5101 atacttcaac tgcattaaga aaaatgaaat tttcaagcga gattgattta ctttatattc
     5161 ggcagctacc cattaggatt caaacagata ttaaaaacaa ggattttgac tctgttttga
     5221 caaaagcaaa tactttaata gatgaagttc taaaatttat tattgaaaat accgaaggac
     5281 cgagtgttaa tattaattta tttaagtcaa aagaattaag aaaagaagta tttggccgcc
     5341 tcaatattaa aactgaaaaa gatatggata atagaatcaa agcccttgtt ggagcactca
     5401 atacattatc agataaaata ctcgaaatga gaaatagtca aggagatgct catgcacatg
     5461 gctcaaatag aatagtaatt aaggaagaag aagcaattct tgttgcaaat tcttctatgg
     5521 ttttgtgcga gtatgtgttt actaagtata aaggattaaa tagataataa aatgcatatt
     5581 ttatagtata caattcgaat ttttatgtta tatactataa tataaaatca atatatgata
     5641 taattgggta tggaaaaaat atcttttgaa acatttaaaa gacccaatgg tcatgatgaa
     5701 tttttagaat ggttggaaac attaccaaaa aaagatagtg cgaagctttt acgtacaata
     5761 gaagaaacag aaaagaatgg gatgctagta gctcaacggt tgaaatgggt gaaaaaatta
     5821 gacactaatt tgtacgaatt aagaagtaag gtaggatcaa acatccaaag agccatctat
     5881 ttccatgtgg acaatggaag gtatgtcatt actcacggat ttactaaaaa aacggagaaa
     5941 acaccaataa ctgaactcaa gcatgcaaaa gaacttagag aggagtggtt cacaaatgat
     6001 gattaaaaaa ttgattgaag aaaagaaaaa agataaagat tttgcagaag catatgaccg
     6061 tgaaggaaga aaactcgaaa ctgcggttgc tctttatcat gctcgggagg aagcagggct
     6121 aactcaagcg gagcttgcac aaaaagcaca tacaactcaa tctactattg ctcgaattga
     6181 gagaggggat aacgtatctt tcgataaact tgatgatatc gccagggcat taggtaaaaa
     6241 gctggtagta gaatttgctt aaaagcgagt tgaaaatata tctataatag gctcctaact
     6301 aatcaattag tttagtgggc ctttttttac tagatagata aaggttgtac tatagtgtaa
     6361 aagacaataa attttatact aaaattactt taaagagaac tagagagaaa ggtacaataa
     6421 atgaaaacca taaatcttat aaaagtattt atagcatcac caggtgatat agcagcaaaa
     6481 aggaatgaag tagaagaaac catatataga tggaatatag aaaatacaga taatacaaaa
     6541 gtgattttga tgcctatacg atgggaaact aatgcgattc ctacttatgt aaataatagc
     6601 tctgggcaaa gtgttattaa taaacaaatt gtagaaaata gggttctgct gcaaagtttt
     6661 aaaaataaaa tcagtttttg tattatttct tcattttaag ctggaattcc caataatatc
     6721 ctgatttcag tgcagactga aaagccgaag agagtgcctt cttttcggct tttcttgtag
     6781 attcctcgaa tggtttccat ccctttaatt gtggtggaag ctgtacgtag actttgatac
     6841 aatttatgtc gacgttttat cgatcgatga tcttgttcta ttaaattgtt aagatacttc
     6901 acagttcggt gctctgtctt agtatataaa cccacactct gtaactttct aaaggcggag
     6961 ccaagagaag gtgctttatc ggtc
//
LOCUS       DAFENC010000085         6749 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.090, whole genome shotgun sequence.
ACCESSION   DAFENC010000085
VERSION     DAFENC010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6749
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.090"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..562
                     /locus_tag="LP493_002710"
     CDS             <1..562
                     /locus_tag="LP493_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBL2134813.1"
                     /translation="VAKNRIHRRFYTSICHQKITTDTTEFKYHEVDAKGIIRQKKLYL
                     DPFMDMFNSEILSYRISEKPNALAVMEGLEEAIQTTNDCPYRRTFHSDQGWAYQMKAY
                     RNKLKEYKIFQSMSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCFEELKSAIDSYIYY
                     YNNERIKQKLNWQSPVQFRKTTVTVV"
     gene            complement(732..1694)
                     /locus_tag="LP493_002711"
     CDS             complement(732..1694)
                     /locus_tag="LP493_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBL2134814.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1696..3135)
                     /locus_tag="LP493_002712"
     CDS             complement(1696..3135)
                     /locus_tag="LP493_002712"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HBL2134815.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            3320..5266
                     /locus_tag="LP493_002713"
     CDS             3320..5266
                     /locus_tag="LP493_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HBL2134816.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            5530..6402
                     /locus_tag="LP493_002714"
     CDS             5530..6402
                     /locus_tag="LP493_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBL2134817.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIEKRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT         2172 a         1153 c         1206 g         2218 t
ORIGIN      
        1 agtagccaaa aatcggatcc atcgtcgttt ctacaccagt atctgccatc agaaaatcac
       61 gacggataca actgaattta aataccatga agtggatgcc aaaggcatta tccgtcaaaa
      121 gaaattgtat ctagatcctt ttatggatat gttcaatagt gagattttat cctatcgtat
      181 ctctgaaaag cccaatgcat tagcggtaat ggaaggtttg gaggaagcta tccagaccac
      241 taacgattgt ccctatcgtc gtacgtttca ctcagatcaa ggttgggcgt atcaaatgaa
      301 agcttataga aacaaattga aggagtacaa aatctttcaa agcatgtctc ggaaagggaa
      361 ctgcttagat aattcactta tggagaattt ttttggctta ttaaaacaag agatttttca
      421 cgggaaagtt tataactgtt tcgaggaatt aaaatcagcc atcgatagct atatctatta
      481 ctacaataat gaacggataa aacagaaatt aaactggcaa agtcccgtcc aatttcgtaa
      541 aacaaccgta acagttgtgt aaaaatatca ttttagagca tgaaaaaagg agtggatttc
      601 tccactccaa aaaagtctaa cttttggggg tcactacaag ttgacaactc ctttttgttt
      661 acaaatcaat tggatatcta caaattgtat tttctaacga attttataga cattaaaaaa
      721 ttaatttaac gttaaatact tcctccagaa agtattgaga ttggtaaaat ataatcctta
      781 tttgtctttt cgcctttaat ttttttcaga agaatatcaa caataagact tgcaatttca
      841 tcaattggtt gtcttattgt tgtcaattgt gggaaaaatt tctcaataaa agaggtacca
      901 tcgtatccaa taatttttaa atcttctggg atattaagtt taagttgatg agcaattttc
      961 atagtgagaa tggctgttaa atcatcagaa acaaaaatac catctggttt gtgatttata
     1021 atagttgact ttatttccat ttcacgacgg atagtagaca gattattagg aattttgaaa
     1081 atttttccat ttggattttg aaaagaaaaa cctagtgcac gtaattctgt gggagaatcc
     1141 gtgttatcat ttcctgtaat cataatggta ttttgacaac catttttttg taaagtctta
     1201 gctgcaagtt ttcccccttc aaagttatct gaagaaacaa tggaaacatt aggagctaaa
     1261 tttctatcaa aagcaacaat aggtgctctc acacgctcat aatcagcaat tccaagatta
     1321 tggcttgatg agattatgcc atcaacttgg ttggcttcaa gcatttcaat gtattctctc
     1381 tctttagcag gatcattttg actattgcaa ataatcgttt tatatccatg tttaaataac
     1441 tctatttcga gatactcaat gagttcagag taaaagatat tactaatatt aggaaaaata
     1501 agaccaataa gctgaggtga ctttccttga agtccacgtg ctaaattatt tggtttataa
     1561 ccaagagttt tcatagcttc atgaactttt tgttttgttt tttctgataa atatccctta
     1621 ttattaatga cgcgtgaaac ggttgttggg ctaactccag ctaattcagc gacatcagtt
     1681 aattttgcta ccattttaat attttaattc aaagtatttt ccagtaggtt cgcctgattt
     1741 gatttgaata ccattttggt gattttcagg gaatacacga ctagtaaaca ctttttctcc
     1801 tttattaata aaaatctcaa tgattgagtt atctacaaaa atgttagcag ttgtttcttt
     1861 agtatcaatt gagcattcac gaatcgtacc aaagtcagtg gcatattgaa tgcctgcttt
     1921 gctgcgatct aaaataattt ttccttcttt ggtatctaca atcaagctaa gtccatttcc
     1981 tttactatca gagaaaagaa gtaactccga tttctgattt ggaggaaaag ttagttcaag
     2041 ctcataagta ttatttgttt ctgcttttgc tgtaaattgt tcagaactag cacgtaatga
     2101 tgtaatagct tctactggat attggtaaag tttaccatct tttattgaaa gttcttttac
     2161 aagactcatt gctccctgat aatcatactt atcagttgga taatcgatat caggtagtcc
     2221 aatccaactg acaatcagag cacgaccatc aggagtattg aatccttgag tcgcatacgc
     2281 ttcaaatcca taatcaagat tttgaatttc tgaagcgccc acaagtttta ctttttctat
     2341 gtcaagcgat tgacagatct taaaagtatt cggatagata ttcccataat ttagctcaga
     2401 tttatccaac ccttgaggac aataaatgag aacaggtttt ttgtctacaa atactagatt
     2461 tggacactca atcatgtatt ctgaaccagt gccgccaaaa tcaaggttgc caacttcctc
     2521 ccatgtttcc acgttattgt catccgcttt gtaaagtttg ataaagcctg atttttctaa
     2581 attttgtgct ccaacaatcg catacaattg tccttcataa ttaaacattt gtggatcacg
     2641 aaaatgatca gttacatcag caggtttatg aataagaaca ttctcacctt tcgtaatgtt
     2701 gtagtcttta tccatccatg ctccgatttg aagtgtatca cgttcccaat tttcatttcg
     2761 aacgtttcct gtatagagta agaatagatt cccctctatt tcatatgcag aaccggaata
     2821 agcgccgtgg ctatctcgtt ttgtgtctgg aagaagttct gctcctgtta catgaaaatg
     2881 aactaaatca tctgattcat tgtgtaccca ttctttcaac ccatgagcag ctccaaatgg
     2941 ccaattttga taaaaaagcg tatattttcc gttaaaaaaa gaaaaaccat taggatcgtt
     3001 taacaatcct gttttaggtt cgatatgata gctagcacgc caaggtgatc gttttacatt
     3061 atccttaatt ttatccatct catctttagt ccaatcagaa taagcacgat atcgtatttc
     3121 tcgaggtaag ttcatatttt actccttcaa tttatctttt tacaactagt atggtaaacg
     3181 ttttccgttg aaaaatcaat catttcattt aaaaaaataa actatatgac aaacgtttga
     3241 catattttta agatatgcta aaataaattt gcatttcagt gaaccgtttt cacgtaaaaa
     3301 taaaaaagga gtgattcgaa tgaattacag taaagtagct tccgacgtaa tacaagcggt
     3361 cggaaaagat aaccttattg cagctgcaca ctgcgctaca cgtcttcgtc tcgtactaaa
     3421 agatgacacg aaagtgaatc aaaaagcttt agacgaaaat ccagatgtga aaagcacatt
     3481 taaaattgat ggacaatatc aagtgattat cggtgcaggt gatgttaatt tcgtttatga
     3541 cgaacttatc aaaaaaactg gactttcgga aatttcaaca gatgatttaa aacaaattgc
     3601 tagtaaagat aaaaaattca accccattat ggcattaatt aaattattat cagatatttt
     3661 tgttccaatt atacctgccc ttgttgcagg tggtttatta atggcattac aaaacttttt
     3721 aacagctgct ggactttttg gaccaaaatc aattgaagaa atgtatcctg cgattgaagg
     3781 tatttcctca atgatccaac tgatgtccgc tgcaccattc atgttcttac caattttagt
     3841 aggtatttca gctgctaaac gttttggagc aaaccaattt cttggtgctg caattggtat
     3901 gatcatgaca acaccagatc ttggtggctc aactgaatat tggaatattt ttggttatca
     3961 tgtttcacaa acaaactatg cttatcaagt tattccagtt ttagcagctg tttggatatt
     4021 atctatatta gaaaaattct ttcataaaaa attgccatca tctattgact ttacattcac
     4081 gccattatta tcagtaatga ttactggatt tttgactttc acagttattg gccctgtaat
     4141 gttattgttg tctaatggaa ttacagacat tattgtttgg ctatataaca ctactggatt
     4201 tattggaatg ggtatttttg gaggaacata ttcacttata gtcatgactg gtttacatca
     4261 atcatttcca gctattgaaa ctcaattact ttcagcgtgg acaaatggta tcggacatgg
     4321 agactttatc tttgtagttg catctatggc aaacgttgct caaggtgctg caacatttgc
     4381 catttggttc ttaactaaaa attctaagac aaaaagtctt gcttcctctg cgggtgtctc
     4441 agcacttctt ggaattacag agcctgcctt gttcggagtt aacttaaaat accgctttcc
     4501 attcttttgt gctttaattg gttcaggaat tgctacagca gtagcaggat tacttaaagt
     4561 agttgctgtt tcacttggtt cagcaggttt cttgggattt ctttcaatta atgcaacatc
     4621 tattccattt tacgtattgt gtgaattgat tagctttgta gttgcttttg caattactta
     4681 cttctacggt aaaacaaaag ctgctggtat ctttaaagca gaagaaattg ctgaacaaac
     4741 accagttaat tcttcaaaag tagcaacaac agatccaata tctactgatg ttgaatcaac
     4801 acaaacaaaa gtttcatcag aaacaattgt tagtcccatt tctggtaaag tgattagtct
     4861 ttcttcagta aatgatccag tcttttcatc agaagctatg ggaaaaggga ttgccattaa
     4921 accaaatgga aacacggtcc attctccagt agatggtact attcaactca cgtttgaaac
     4981 tggacatgct tatggtatta aatcaaataa tggtgctgaa gttctaattc atattggtat
     5041 tgatactgta tcaatgggag gaaaaggatt tacacaaaaa gttactacta atcaaaaagt
     5101 tagaaaaggc gatattcttg gagcatttga ccgttcaatg attgagaaag aaggtcttga
     5161 tgatacaaca atgattattg tgaccaatac ttcggattat tcagaagtaa atatagtagc
     5221 tgaaaataca gtcactgagg gtactgattt acttgaaatc aaataaatgt atttccctga
     5281 gtaaagatgg aattttcttt ccaaaatcaa ataatataga ttaatcaaat atttgagaat
     5341 aacattttat ttaatctttt catatatcaa ttgtatgaaa aattattaga attttaaaaa
     5401 atgataaaaa ttcaaaaaga aaaaatagta gttatttact tgtcatgtta ctaaataaaa
     5461 aaataattta aatatgatat atagtcattt atttagtgat ttcattctaa aataaaggga
     5521 gaaatgtcta tgctatacgg tgcaattgaa gcaggcggca caaaatttgt gtgtgccatt
     5581 ggcgatgaag aaatgacgat caaggaaaga gtgagctttc cgacaacgac acctgaggaa
     5641 acaatgcctt tagtcattga cttcttcaaa caataccaag cagatttagc aggaattggg
     5701 attggctcat ttgggcctat cgatatccat cgcgattccg ccacttatgg gtacattacc
     5761 tcgaccccga aattggcatg gcaaaatttt gatttcatcg gtaccatgaa aaaagaattt
     5821 ccgatcccga tttcttggac aacagatgtc aatgcggctg cctatggtga gtatgtcttc
     5881 ggcagtggca aaggattgag cagtgtcgtt tactatacga tcggtacggg tgttggcggc
     5941 ggtgccttac aagaagggcg ctttatcgaa gggtttagtc atccagaaat ggggcatatg
     6001 ctcgtcgtcc ctcatccaaa agatgacttt gctggcagct gtccatttca tggcaactgt
     6061 ttagaaggga tggccgctgg acccgccatc gaaaaacgct tagggaaaaa aggacaagag
     6121 gttgcagaag atgatcctta ttgggaaatc gaagcctcct atattgctca atgtgcctac
     6181 aatacaacct tgatgttttc tccagatgtg atcatttttg gcggtggtgt gatgaaacaa
     6241 cgccatatgc tgcaaaacgt ccacgacgca tttgcaaaat tggtcaatgg gtatgtcgaa
     6301 acacctgagt taagcaaata tatcgtgacc ccagcattag aagacaacgc tggaacgctc
     6361 ggttgtttgg cattggctcg agaagcggtc ttacattcat aaacgaaaaa aggctcttcg
     6421 acatttagtg ttggtagaga aagatacaac tgaaaattta gtcataacca gttaggcaga
     6481 gtgcttaact ggtttttgtt ttacttggaa gatcaagcct tgaatgagat aaattcttgc
     6541 tcgaaagtta tggaaatttc gatagccgta ggccacttgt attgtgcaat agttttttac
     6601 aaaaaaaagg gggtgcggat atttttttgg acctttttaa caaataggtt ctgttgcaaa
     6661 gttttaaatc tactatcaga taaggtagaa taatagaaaa agatagcagg aggaatgacg
     6721 atgagtcatt ttaaaggaaa gcaatttca
//
LOCUS       DAFENC010000086         6642 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.091, whole genome shotgun sequence.
ACCESSION   DAFENC010000086
VERSION     DAFENC010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6642
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.091"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(1..859)
                     /locus_tag="LP493_002715"
                     /pseudo
     CDS             complement(1..859)
                     /locus_tag="LP493_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            1102..1557
                     /gene="tnpA"
                     /locus_tag="LP493_002716"
     CDS             1102..1557
                     /gene="tnpA"
                     /locus_tag="LP493_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBL2134818.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1822..1920
                     /locus_tag="LP493_002717"
                     /pseudo
     CDS             1822..1920
                     /locus_tag="LP493_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2603..3421)
                     /locus_tag="LP493_002718"
     CDS             complement(2603..3421)
                     /locus_tag="LP493_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBL2134819.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            3582..4271
                     /locus_tag="LP493_002719"
     CDS             3582..4271
                     /locus_tag="LP493_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBL2134820.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4285..5787
                     /locus_tag="LP493_002720"
     CDS             4285..5787
                     /locus_tag="LP493_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL2134821.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            5800..6276
                     /locus_tag="LP493_002721"
     CDS             5800..6276
                     /locus_tag="LP493_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBL2134822.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
BASE COUNT         2172 a         1033 c         1202 g         2235 t
ORIGIN      
        1 acttgtcctc gataagaatt gtagcgccgt gatttacgtg tgtatgtcgt tacttttatt
       61 cctagcttct tgatcaggcg ctgaactttc tttttattga tagagaaacc gcggtttctt
      121 agttcattgg tcatccgtaa acagccataa tccttgtgct tctcccgaac tttaagcatt
      181 tccgcttcaa tctcttgatc tggattttta cggtccaatc gtttttgcca gtacataaag
      241 attgccttag ggaactttaa agtttctaga agctcaacta atttaaacgg tcctcggagg
      301 cttgcgatga ttcgtgcgat tgcttcattc gtcgttgttg ggcttcctgt tttcgcagct
      361 tcctcaattc ttttaaaaag gcattttcaa tttgaaggga acggactcgt ttctccaact
      421 cctcgatgcg ttcacgttct ttagacgttg ctttagttgt agattttttc ttatttttgg
      481 gttcattttt cttagacaag ataggtggac atcctttcgt ttttgagagt ccatcgatcc
      541 caccctcacg gaattgacgc atccaactag cgatcaaatt agggttgttc atgttaagtg
      601 tgttggcaac ttcacgatag gacagctcac ttgttagata taactctatc gcatccagct
      661 taaattgaac agaatatttt ttcttttgtc gctttcttac tagaccctct tcaccaaatt
      721 cttgataggc attgatccag cgcttcactt gtgatggagc cttaatggaa tatttctttg
      781 ccagataatc acttccgcct ttaccatcca agtaatcatg aacgatcttt aatttaagtt
      841 caaaagtata cttagccata aaaaataccg acctccaaaa gttagatttt ttggtctaac
      901 ttttgggggt cggtacaaaa cttaaaagtt ttagaccctt ttattttctt aatgacttca
      961 gtcagttttg tgcgtaaagc gtgcgaaaca agaaaaccgc gcgtttctac gcgtggaaga
     1021 agtatcttta gcgataaaaa ctcctttcga tatactagtg agtggctacc aaccgctcat
     1081 cagatcgaaa ggagtttttt catgtcaaat gacgataaaa gtttagcata tactcgttgg
     1141 aattgtaagt atcatattat ttttacacca aaatatcaac gaaaagtaat ctatgggcaa
     1201 ttacgaaaag atcttggaaa aatacttagg aagttgtgcg aaatgaaaga tgtggaaatc
     1261 atagaagcac atgcaatgct agatcatatt cacatgcttg ttcgagtacc accaaaaata
     1321 tgtatatcca gttttatggg gtatctgaaa ggtcgtagtg cggtactaat ccacgagcag
     1381 cacgcaaatc tcaaatataa atacggaaac aaatcctttt ggtcgaagag atactatgtg
     1441 agtacagtcg gattgaatca aaagacaaat gaaaaataca tccgtgaaca agaagctgat
     1501 gatcgcattc gatatattat aagtaaaaga gagtacgtag aaccatttaa aaaataaaga
     1561 gaagtaagtg agtgaagatg agcagttggc ggtcttttaa aaatcccctt ttaaggggca
     1621 gcgagtgtcg accccttcta gggggattaa aaatacaccc gtcctcacgg gtgtatgggt
     1681 tactgataga cttgatttta actggtgtca gaaacttatg tccagaaagg gtgatgaaat
     1741 tttggcaatt tacggctatt caagaattag cacaagcaac caagattaca aaacacaaat
     1801 tcaaacatta gaaaatgctg gcgcagaaat aatcttccta gaaaatcact ggattatcga
     1861 acacctttgg aagtattttt gagttacgta agtattgatg atctgtctaa cttaatttga
     1921 caattaagag tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat
     1981 gaactaataa ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc
     2041 ataaactttt aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca
     2101 taacattgaa gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt
     2161 cttataaaca agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt
     2221 tatagaaaac attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc
     2281 agtaggttcc tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt
     2341 atttaagaga ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta
     2401 cacgtttttc tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc
     2461 aagaaccgta ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa
     2521 taagctatca agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta
     2581 ggtttagcta agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt
     2641 tttctcttaa ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat
     2701 cacaaatata aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa
     2761 tggctgtttg taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta
     2821 tagcaataat ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg
     2881 ttttcccaga taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt
     2941 gggcttgaaa atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat
     3001 tttctaaatc aagactagta tttccactag atcccactcc aaatatatat atgttttttg
     3061 attgagtgat cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg
     3121 aatagagagc ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat
     3181 gttctttttt ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag
     3241 aaaaaccaat tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct
     3301 taatatcact catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga
     3361 cttttttttc agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca
     3421 tacaaactcc tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact
     3481 cctaaatact ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag
     3541 ttgttatcca aaaataataa aaaattggag tgtttaggat aatggataaa aagaggtttt
     3601 tagatcttat ttcaaaaggt ttgattgttt cctgtcaagc attacctggt gaaccatttt
     3661 acaaagagga agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag
     3721 ttggtatacg tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac
     3781 caatgattgg aattattaaa agagattatc caccagaatc tccattcatt actgccacta
     3841 tgagagaagt agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc
     3901 ttagaaatcg acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat
     3961 atcctcatca gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata
     4021 aagcaggaat agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac
     4081 aagatgggcc agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg
     4141 ctgagggaag gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag
     4201 gtattgttgt gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag
     4261 cattaagtta gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc
     4321 atgttaccaa ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta
     4381 acaaatgaga gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt
     4441 ttaagtatta tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca
     4501 attggtattg ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga
     4561 gtagcttatc tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa
     4621 gatgcaacac tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt
     4681 ttacacaatc gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca
     4741 agatttattc cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta
     4801 atttggccac caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt
     4861 agtttaggaa cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac
     4921 cacaccattt accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga
     4981 tcaacaattg ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact
     5041 ggtctgttta cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga
     5101 ttaccagcag catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat
     5161 ggtgggcttt attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt
     5221 gaatatatgt ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga
     5281 ttatcttttt attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt
     5341 ttgatcgact ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa
     5401 ttaattcctt ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc
     5461 aaaaaattta aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa
     5521 gtaataaaca aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt
     5581 ggaaaagaaa atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg
     5641 aatggggaga ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa
     5701 gtgaagggtg gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc
     5761 aatcaaatat taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag
     5821 aaaaaacaag aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta
     5881 aatgatcctg tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt
     5941 tcaaaaattt atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct
     6001 attaatataa aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt
     6061 gaattacaag gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa
     6121 acctcgttgg ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt
     6181 atagttgttt ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt
     6241 gctcatggga attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa
     6301 aataagctaa ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt
     6361 ctgttcattt ttttatttta ttagtaatga ttccccatgc caaatcatga tccgtaattt
     6421 aaagttataa aagcttcgaa atccattggc atttccttgg aataccttga tatgattatt
     6481 caaatataaa atatagagag aagagagaga gggaagatat ttataaaggg caaagttatg
     6541 tttactcaac ttaggaaata gaaatagatc aatttatatt ctcttgtcaa tcgaatatga
     6601 accttagcac tatataccaa atatagtaaa atgctgaaag at
//
LOCUS       DAFENC010000087         6387 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.092, whole genome shotgun sequence.
ACCESSION   DAFENC010000087
VERSION     DAFENC010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6387
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.092"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            330..1175
                     /locus_tag="LP493_002722"
     CDS             330..1175
                     /locus_tag="LP493_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL2134823.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1456..2676
                     /locus_tag="LP493_002723"
     CDS             1456..2676
                     /locus_tag="LP493_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HBL2134824.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2673..5393
                     /locus_tag="LP493_002724"
     CDS             2673..5393
                     /locus_tag="LP493_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL2134825.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5377..6321
                     /locus_tag="LP493_002725"
     CDS             5377..6321
                     /locus_tag="LP493_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBL2134826.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
BASE COUNT         2379 a          987 c         1231 g         1790 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt
       61 gaactaatag agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat
      121 agttggttat tataaaatag taatatagct gatttggatt caattcatat ttatttataa
      181 atcaaaaata cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta
      241 cttacttaaa ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc
      301 agtgaattta taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt
      361 tagacggtac tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga
      421 aacatttacc ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta
      481 ataatattct caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg
      541 gatttgatgg agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa
      601 ttgattctgt cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat
      661 ctcagaatta taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta
      721 tcaaagagct aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata
      781 atattgagga aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc
      841 ctaatcgtca attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg
      901 ttactgaatc ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg
      961 tgtttgatcg tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag
     1021 atagtttaaa tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata
     1081 gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag
     1141 tatctcaagc atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata
     1201 gaattctaaa tacggaaaaa tggagcataa attccagtac aaatagtact tcttcagtgt
     1261 caaacgaagc gaatataaca tagatattta ggattgtgac aaaaatcatg tcacaatctt
     1321 tttttcgaat aaacttattt tttgaagtcg gccatttatc gtaatttctt tgcataatac
     1381 gaacaaattt tcggttattg atgaaaaaaa acattgaaaa tggtatgata aaagaaaaaa
     1441 aggaggaaat ttttaatggt gaaatttatc catgcggcag atttacatat ggatcggtca
     1501 tttgaaggac tgacaactct tgataaaact gtacaggaaa aactattgaa gacgaatctg
     1561 accgttttat caaatatcat tgaacaggca ataataaata acgttgattt tgttttactt
     1621 gcaggagata attttcatca aaatcgtcct tcattaaaaa tacagaaaca tttttcagaa
     1681 cagatgaaac ggttagaaaa gaaccatata cctgtattta taatattcgg aaatcatgat
     1741 ttctatcaaa aagagcggta ttggttctcc tttcctaaaa atgtccattt atttacatcc
     1801 gaaacggtag agacaaaaaa aataacgata aaaagtggag aaactgtctc tctcagtgga
     1861 tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga tggaatttcc ttctagagaa
     1921 ctcacagatt accatattgg gttgtaccac ggggaacctg gcgtctctca aaaaggaaac
     1981 tatgctcctt tccaaccctc aaagatgcaa gaaaagggat acgattattg ggctttaggg
     2041 catatccatg tgccaacggt cttaaatgaa aagcaaacaa ttgtttatcc aggtgcgcct
     2101 caaggtcata ctaaaaagga acaagcttct acatctattc tactagttga attaagtaaa
     2161 ggaagttgcc aaatacatcc gattaaagta gcagaggtct attggaagac aaaggaaata
     2221 tcattgagga aagcaagaac gacaaaagag gtcattgttc acattcgtca gcagctttca
     2281 aaagtagagg atggatttag tttaattgag ataaaattaa aagattatga ccatctcaat
     2341 acagatgttt tggaacggat acaatcagga gagctattag actatttgtt agaggaattc
     2401 tcagatagga taaatgattt ctttatttgg cgtatttctc tcatagagaa tactttttat
     2461 acgaagaccc cacttgctgc ttctgctaaa ttgatggaac agttatttca atactatcag
     2521 acacctcaag atttccaaca aattttaaat gaagtatata gtcatcaaga agcggctaga
     2581 atattgagcg aactgccgga atatcaagaa gaaacacttg aaaaagccaa gcagctgctt
     2641 aatcaagatt ttttatttga ggaggatcag gaatgaagat tttaaggatc gagattgctg
     2701 cttttggaaa atggcgtcaa aaaagttttg acttttattc aggcaatcag ctgatctatg
     2761 ggggaaacga agcaggaaaa tcaacgattt atcaatttat tcaagcaata ttatttggtt
     2821 tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa agacggctca gcctatggcg
     2881 gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc tgtcgagcgc tacaagcagc
     2941 aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt gggaagtgat gagttactag
     3001 aaaaactgat cgcacctttg acgaaagagt tattccagca ggtatttact ttccagcaag
     3061 agcagttgat ggaactagat catttgagag aaaaagagct acatgatgcg ctgatttctt
     3121 taggcatcac gggcagttct caagtattcc aaaagcggca agaatattat cagaaagcac
     3181 aacaattatt caagaaaaaa ggccaaaaat tactaatcaa tcaaaaatta aatgaatgga
     3241 aagagctgca agaaaaaatt catcaaaaac aagaacagga agcttatttt ggcaagttga
     3301 tccaacaaga acaggaatac gagtcgcaac agcagcagtt attggcacaa ttaaaagagg
     3361 cgaacaaaca attttcatta gccagacagc aagaacttaa tttttcttta tatgaagaat
     3421 ggcaatctct caaaaaaaac agcactacag gtcttcctga tgagcaactt cttttagatc
     3481 tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg tttggaagaa ttagaagcaa
     3541 cactggaaaa gcatagcggg atggatcagc agtcagccag atattatttt tatttagagc
     3601 aggagcagga actaaaagat ctccagcaac ttcaatttac agcggaacaa ttaaacgaag
     3661 aatggcaaag attacaaatt gagactagag aaacaaattc agaattgaag attttggaac
     3721 aaaggtggca ttggcagaaa aatccgttac cggaagaatt tttatatgaa gaagaatgga
     3781 agcatcttct ggctgaagaa agaaggattg ctgatctaga aagccagatt tctgtgcgtc
     3841 tccaaatagc taaagaacag caagagatga ttgaagcaga agtgaatgac ttggaagaga
     3901 cctatccagc attattacaa aatcagtcag agatagcacc agtctcttca tctaaaccgt
     3961 atatgctgat ggctggcgga gcaataatca ttgcaggtat atttgtacca atgcccttga
     4021 aagtgatcct tttactaatt ggtgcaggca tgattggcta tttcttctac aaaaggcaac
     4081 caaaaattaa aactaaaaat gatttctctg agataaaagg aatgtggcaa gaaaaactag
     4141 gacaacttga tctagcctta gctcaattag ctgaagcaga agaaaaacaa aagagaactg
     4201 gagaagaaaa acagattctt cagcaagaag tatatcgttt tgcggatcat cggcacttag
     4261 gaaagatgga tacgctcaaa ctcatgaaag aatatggaca ggaagtcata gattatcaga
     4321 aattatatgg cgtatttgag cggaaacata aaagagaaca ggaaatacaa gaaaaactac
     4381 gacaaatcga ccaaaaattt gagtttgtta aagaatggtt accgatacaa gataagacaa
     4441 tttcagaaaa aatggtattg ctttcccgtt ttatacaaga gatggaacag atgaaatttg
     4501 ccagaagcta tcagcaaaat actttattga agcaagaaat caatcaattg aaaaagaaac
     4561 aaaaagtatg gatacaagaa tacagcgaac aattgactca agcaggctta tcttatcctt
     4621 cggaagtacc tgtcttttta caaaaagcca aacaagccga acagcagatg aaaagataca
     4681 atgaattatc ggaaatgctt actccactat ttcctgaaga gctgacaaaa gagaaattat
     4741 ctgtaagact gcgccaactg aaagaaaagc aatcccaact ccagcaagaa gaaaaagaag
     4801 caagtgaaaa tcggcaacga ctccaacttc aagtagaaga gttgcaaaga gacggcacat
     4861 tggacgaact ttatcaacaa gctagccggc aaaaagcaaa attacaggaa ttactggagg
     4921 aatggggagc acttgaaatc gccgggacat tcttaggtga tctttcaaca gagatgagtg
     4981 aaagacaatt accccagttg ttaagagcag caggtgatta tttaggtatt ttaacaaaag
     5041 gaaattatca gaagatatta ctgaaaaatg atacactgac tttaacagac ggatatacag
     5101 aatttcccat ctatgagtta tctacaggta cgaaagatca gctgattatg gcgatgagat
     5161 ttgcttacct ctcattagaa gctaaccgtt cgatatgccc gatcatcatt gatgatggct
     5221 ggcttcatta tgatcatcag cgaaagtatc aattagctga acttttagct aaatttggag
     5281 aaaagtatca aataatttgt ttttcttctg ataaagaaat ggtaagctat taccatgaga
     5341 tgaaccaaat cgtaaaacaa ttagaaggag caaataatga aaaaaattcg tgatttagta
     5401 atcgatgagc agtttgaaca atttgtcctg atcaaaagtg cagatgtaag aatcgctaaa
     5461 aacggaaaaa aatttattgc ttttactttc caagatactt caggtactat cgatggtaaa
     5521 tactgggatg cttcggagga ggaaatcaat aaatttacag ccggcacagt cgtttttcta
     5581 aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa agattcttca tatgcgctta
     5641 acaagggtag atgagccagg agagcctagt ttatacatgg aaagagcccc tttgaagaaa
     5701 gaagaaatgg aagaagaaat caatcaattg ttgtttgaga tcaccaatgc gcattggaat
     5761 cgtattgttc gctatctact taataaatat caaaaacaat tttttgagtt tccggcagca
     5821 aaaagaaacc atcatgcatt tgccagtgga ttagcttatc atactttgac aatgcttcac
     5881 ttagggaaat caatcgccga tgaatatcct gagctgaatc gagcattgtt gtatgctggt
     5941 atcattttgc atgatttagg aaaggtgatt gaactttccg gtcctatgtc gacagaatat
     6001 acgcttgcag gaaatttgat cggtcatctg gtattgattg acgaagaaat aactaaagcc
     6061 tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc tcgtattacg tcatatggtt
     6121 ttagcacacc atggcttatt agaatatggc tcacctgtac gtccaagaat aatggaagca
     6181 gaaatattac atcaaatcga caatatcgat gcttcgatgc agatgatgtt gacttcgatt
     6241 cgtcaaacag aaccaggaaa atacaccgat cggattttcg gtatggacaa ccgaagtttc
     6301 tatgtaccaa aagatttata gcaaaaattt atttttttca ttcaaaacaa aaaaagcgag
     6361 acataagtct tcgctttttt tgttttc
//
LOCUS       DAFENC010000088         6286 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.093, whole genome shotgun sequence.
ACCESSION   DAFENC010000088
VERSION     DAFENC010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6286
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.093"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..177
                     /locus_tag="LP493_002726"
     CDS             <1..177
                     /locus_tag="LP493_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134827.1"
                     /translation="QSLVLLAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGV
                     KDVLLNLFNRIVGA"
     gene            190..690
                     /locus_tag="LP493_002727"
     CDS             190..690
                     /locus_tag="LP493_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBL2134828.1"
                     /translation="MEQIRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELKGTPIGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCNDMSDVAYYLIVEAGDLGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFELM"
     gene            787..2634
                     /locus_tag="LP493_002728"
     CDS             787..2634
                     /locus_tag="LP493_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBL2134829.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQIYEISKNQTSILELLDGYNSDLISEYKN
                     EIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLKKQVEKLSHKSYKDVYDEYSKE
                     TDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVTDEIDEHRGELIKNLVTNRAKI
                     QTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRGIKNLVKSYLKMN"
     gene            2637..3533
                     /locus_tag="LP493_002729"
     CDS             2637..3533
                     /locus_tag="LP493_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL2134830.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNLYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            3583..3972
                     /locus_tag="LP493_002730"
     CDS             3583..3972
                     /locus_tag="LP493_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL2134831.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            3959..>6286
                     /locus_tag="LP493_002731"
     CDS             3959..>6286
                     /locus_tag="LP493_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBL2134832.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKFQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITSRLKEVAKQRIDIQTDALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKSLKKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RCYSKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGIPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPNRCLIEEKPRCLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLEN"
BASE COUNT         2119 a          933 c         1346 g         1888 t
ORIGIN      
        1 caatctttag tcttactagc gattgtggtc attggtttgt ttttaggatt taaacgcgag
       61 ttttccaaac tgattggctt cttggtgatt gctttgattg cggtaggtct ggtctttaat
      121 gcttctggtg tgaaggatgt cttactcaat ttgtttaacc gaattgtcgg tgcctgaggg
      181 ggaatcacaa tggaacagat acgtgtttat attgcgaacc ttggaaaata caatgaaggt
      241 gagttggtgg gggcatggtt taccccaccc gtcgattttg atgaagtgaa agaacggatt
      301 ggattaaatg acgaatatga agagtacgca attcatgatt atgaactgcc ttttgagatt
      361 gatgagtata caccaattga ggaaattaat cggttgtgtg gtttagcgga agagcttaaa
      421 ggaacgccaa ttggtgaggt cgcttcagag attcaacatg ccttcttcaa ttctttcgag
      481 gaaatggtag agcatgtgga tgatatcatc tattatcccg attgtaatga catgagtgat
      541 gtagcgtatt acttgattgt agaagctggt gatttaggcg aagtaccaga acacttgaag
      601 acgtatattg attttgatgc gtgtggtcga gacttggaga ttggcgggaa ttatttggtt
      661 acgagtcgag gggtttttga actaatgtaa atcatttgtt agaattgacc agaaatttct
      721 atcgtacttt tacttttcta tttgatatac tgaaatagaa aatatttgtt gataggggtg
      781 ttactaatgg ttggcaataa gtggtacaaa tgtgatcttc atattcattc aactgcgagt
      841 cagtgctttc aggataaaaa ggttactgct aaggaatggg tagaagaatg tttaaacaaa
      901 ggactcgatt gtgttgcatt aactgatcac aatacagggg aaaatattga tgaatataag
      961 aaagtggcta tcgaaaatgg cttagatttt tttcctggag tggaattaac gtgtggagaa
     1021 aatggaactc atttactagt cctatttgat aaaagtgcat gtacaaatga tatctctgat
     1081 ttcttaacca agatgggtat aaaaagagag gattgggcca gcgctgcagc ttgctcaatg
     1141 aaatcagttt tagaagttat tgattttgct gagcacgagg gcttgctcgt tattcctgca
     1201 catatagatg agtttaatgg aatttcttca gcaaaatttg gaaatctagg aaagatattt
     1261 gaatcagaaa atatatatgc agtacagacg gttcaaaaag aattttttga aaatcgctca
     1321 caaatgattc cctcatctaa gcgtgacact atctatgata gtgtgaatgc cagatatgat
     1381 ggtagagttg gaaaagatac tttggaatct tggtataaat cagttgttga ggcagaaaaa
     1441 aataatatga catttcttag cttttctgat aacccacact cgaaaggaaa ttcaaaacat
     1501 ggactttggg gaataggcac aagatattcc tatataaaaa tgaaggacga acctgacttg
     1561 ggatcacttc gcgatgcttt aatgctaggc gaaactcgag ttcattctga tttttctaat
     1621 ttctccatta atgaaaatga agttttattg gaaaaattaa gcttttctgg gaccactctt
     1681 agcacaaaag aagttgtagt cgaattcagc gataatttaa cttcaattat tggaggaaga
     1741 ggaacaggca aatcttgtat tacaagattc ttggtctatg tccttggaaa ggaagcagaa
     1801 cttgatcaat tttctgaaat acaaagtgat tatcagaact ttgcacaaat tgaacataat
     1861 ggctctggaa tatttttgaa ggatacaatt gtgaaactga atattttcta taaggggaca
     1921 aaatatcaaa taataagaac acaggataga cattctattt atgaatttac acaagagaat
     1981 ggtctggttg aaaaagaaac agaacggttg agaatgattt ccgataaggt gagtatatac
     2041 tctcaaaaac aaatttatga aatttcaaaa aatcaaacta gtatactaga attactagat
     2101 ggatataact ctgatttgat ttcagagtat aaaaatgaga ttgaaacatg tgtaaacgaa
     2161 ataagaaaat taaattggga tattgtttct gtgaaaaaag aaatacaaga taaggcgaag
     2221 gtagagcttg aaattgaaga tttaaaaaaa caagtagaaa agctatctca taagagttat
     2281 aaagatgttt atgatgagta ttcaaaagag acagatattt atagggaact gaaacgtgat
     2341 gtggaggcac ttaaggaaat tcccaaaaat ctaactgata gtgttgacaa aattgacttt
     2401 ggcaatggta taaaagttac agacgaaatt gatgaacacc gcggagaatt gattaagaat
     2461 ttagtgacca atcgggctaa gattcaaaca ataattaatg aaatgtcaga tgaaattgat
     2521 agttatagag cagagctgaa taaatcagat tggaaagtta actataatga ggtttcaaag
     2581 aggtatcaaa gaggtatcaa aaacttagtg aagagttatc tcaagatgaa ttaaaaatgt
     2641 tacaaaacct tgattcttta tatcaatctt tatcaaaaac tgaagagcga ttggaagaaa
     2701 ttattcaaca agaaataaag cttaaagatt accaagttga ggttgactca gcaatgtcaa
     2761 gaatgaataa atcatatcaa aatctctatt ctgagagaag tagttcctcg cgcgaaattt
     2821 tttctgatat tacaggaata gaggctacta ttcaaccaaa tagggatttc aataattatg
     2881 ttaaagagct cagagcttgt attaataagg aggacacttt tgacagtgag tttggatctc
     2941 ttattgataa gctgacaaaa aattccatta ctaatcaaga tatatataat gacatacttg
     3001 atataagagt tagtggggaa agtagtattt tttcagataa aaaattaatc aattctataa
     3061 gaaaattgaa tgatgcacaa gttcttgaat tacaaaccct taagccaaat gatttagtag
     3121 ttatccgact tgaactaaat ggaaaaaaag ttagtttatc gaatgctagt gctggtcaaa
     3181 agacatctgc aattctttct atgattttgg cgtatggaaa ttcaccactc atattggatc
     3241 agcctgaaga tgatttggat agtcaattaa ttaataactt aatcgtaaga agtatcatta
     3301 caaaaaagga aaacagacaa attttaattg taactcataa tgcaaatatc ccagttaatg
     3361 gtgattcaga atggttgatt agcatgggag attcaaaaga aatatcggct gatcagtgcg
     3421 ggtcggtaga tgaacccaat atcaagccaa gaatatgtac tgtgatggaa ggtggcgagg
     3481 atgcttttac aaatagagcg aaacgctatg gttttaaaca aattgtagaa taacactaga
     3541 gggtgagaca tattattatg tccgcccttt ttaggaggaa aaatgaaaaa aataaaaagc
     3601 tataccagta tctgggcagt tgaaaaagtc atttacgcaa tcaatgattt tcagttgcct
     3661 tttcctgtga cttttaacca aatggcttgg ttcgttttat ctttactgtt tgtcatcgta
     3721 tttgcccatg tgcctccact atctatgata gaggaggtct ttttaaaata cttaggcata
     3781 ccggtggctg tcacttggtt tatgtcgcaa aagacgtttg atggcaagaa accactggga
     3841 tttttacgat cctttatcag ctatcacttg cgatttaagg tgacttttgc aggaaagaaa
     3901 gtcaaagaac agaagaaacg atgggatgaa cccagtactc ttgtaaggag tgtgaactat
     3961 gtatccgatt aagtatattg aaaataatct cgtctttaac caagaaggcg agtgttttgc
     4021 ctactatgaa ttagtgcctt acaattactc ctttttgtca cccgaacaga aatttcaagt
     4081 gcatgataac tttcgccaac taattgcgca aaatcgtgaa ggcaagatcc atgcgttaca
     4141 aattgccaca gaaagtagta ttcgcgccac acaagaacga tcaaaaaaag aaattaccag
     4201 tagactcaaa gaagtagcga aacaacgaat tgatatacag acagatgcat tagtatccat
     4261 gattggcgat agtcagattg attatcgctt ttttattggc tttaaactaa ttgcgacaga
     4321 tgaagaagtc aatctaaaga gtctcaagaa atctttcttt tctgggcttc aagaatttgt
     4381 ctatggagtg aatcatcatt tgatgggcga ttttgtttcc ttatccaatg aagaaattcg
     4441 ctgctattct aagcttgaaa aattaatgga aagcaaattg gctcgaagat ttaaagtcag
     4501 gcgagtcaca ccgagtgacc tgacgtattt gattgaacat atttatggcg aaaaagggat
     4561 accgtttgaa gaatacgaat ttcagctacc aaagaaaaag ctaaaatcag aaacactggt
     4621 gaaacgttat gacttattac gtccaaatcg ttgtttaatt gaagaaaaac caaggtgctt
     4681 acggatggaa catgagaatc atgagtcgta cgtagcgtat ttaacaatta atacaattgt
     4741 gggggagatg gaatttcctt cctcagaact tttctattac cagcaacaac aatttacatt
     4801 cccaatcgac acaagtatga atgtagagat tgtgacgaat aaaaaggctt tagctaccgt
     4861 tcgtaataag aaaaaagaac tgaaagattt agacaatcat gcttaccaat ctgacaatga
     4921 aacgaattcc aatgtcttag atgctttgga ttccgtggat gaattggaaa ccaccttgga
     4981 tcagtcaaaa gaatctatgt acaaactgag ttatgtggtt cgagtgagtg ccgaatcagt
     5041 ggatgaacta aagcgacgct gtgatgaagt gctcgatttt tatgatgata ccaatgtaaa
     5101 actagtccgg ccctttggcg atatgatggg gctacatgaa gaattcttac cctcaagtaa
     5161 acgatatatg aacgactata ttcagtatgt tacgtctgat tttttggcgg ggcttggttt
     5221 tggggctact cagatgctag gagaattaga agggatttac tttggctaca atgtggatac
     5281 aggtcgtaat gtttacctga aaccggcatt ggcttcacaa ggagtcaagg gttcagtaac
     5341 caatgcgctg gccgccgctt tcctgggttc tcttggtgga ggtaaatcct ttagtaacaa
     5401 tctcttagtc tactatgctg ttttgttcgg tggtcaagct gtgattgtcg atccaaaagg
     5461 ggagcgagga gggtggaaag aaaccttgcc agaaattgcg gatgaaatca gtatcctcaa
     5521 cttgacgagt aagtcagaaa atcaaggtct gcttgatcct tatgtgatta tgaagaaaaa
     5581 gaaagactcg gaaagtttag caattgatat tctgactttt ttaacaggaa tttcaagtcg
     5641 agacggggag aagtttcctg tgttacgtaa agccattcga acggtgactc aaagtgatca
     5701 acgggggtta ttacaagtta ttaacgaatt gcgaaaagac gggtcaccaa tcgcggaaaa
     5761 tatcgccgat catatcgagt cctttaccga ttatgatttt gctcatttgc ttttctcaga
     5821 cggctcgatt acccaatcga ttagtttaga taaacagcta aatatcattc aagtggcgga
     5881 tttggtttta ccggatgcag aaacgacttt tgaagaatat accaccatgg aattgcttag
     5941 tgtttcgatg ctaatcgtca tttccacttt tgccttggac tttatccata gtaaccgaga
     6001 aatcttcaaa attgtcgatt tggatgaggc ttggagtttt cttcaagtgg ctcaaggaaa
     6061 aacgttatcg aataagcttg ttcgtgctgg tcgggccatg aatgctgggg tctatttcgt
     6121 cactcaaaat agcgacgatt tattagatga acgtttaaaa aataatatcg ggttgaagtt
     6181 tgcttttcgc agtaccgata ttcatgaaat caagaaaacc ttggaattct ttggtttgga
     6241 tcaggaggat caaagcaatc aaaaacgcct gcgagatttg gaaaac
//
LOCUS       DAFENC010000089         6176 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.094, whole genome shotgun sequence.
ACCESSION   DAFENC010000089
VERSION     DAFENC010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6176
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.094"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(1..486)
                     /locus_tag="LP493_002732"
                     /pseudo
     CDS             complement(1..486)
                     /locus_tag="LP493_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            507..1709
                     /locus_tag="LP493_002733"
     CDS             507..1709
                     /locus_tag="LP493_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit R"
                     /protein_id="HBL2134833.1"
                     /translation="MCTKLLQNTAHKNPYKTVDEATQLDLVIVVNQLLTGYDSKWVNT
                     LYLDKSLEYQNIIQAFSRTNRLNGPEKPFGTIRYYRKAHTMEQNIEEAIELYSGKQAK
                     GLFVEKLYNNLEKLNDIFEEIKSVFNISGIENFSHLPEVPGEIKQFVNLYNQLIHCYE
                     SAMIQGFTWAKSTYEIQDYEPITVVITEYEFNILAQRYSEIEREPRDGNDSIAYDIDY
                     QLPEGSRSRINYEYLNTNFKKYMNIKEERDSNLIQSLLNDLHRTFAQLPVELQPYAEM
                     ILNDVNNGELVIKEGWEFTDYLNEYQLSEEDDFIQDLVDSTNINEALLREMLDLRLTE
                     VNINEYSRFDKLKSSVNVGHFSGYIEKNLGKMVIPIKVNMLIDRLLRAFLLEDVFDVT
                     EYIKNYFN"
     gene            2442..3410
                     /locus_tag="LP493_002734"
     CDS             2442..3410
                     /locus_tag="LP493_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL2134834.1"
                     /translation="MDVAKTVNAIVEKNDGEISGIYLVACGGSLVDMYVSDYFLKAEA
                     SKCITGLYTANEFNHVTPKQLDDKSVVILCSHGGNTAETVKAGEVAQARGAVTVGLTH
                     NKTADLLKVSDHSFLYEWGDDAKIVNNPMAIILDLTVSLVNVTETFEHYGKFREGMKV
                     IDTVIENGIKQVQDRIKVFADKYKDETMFYILGSGPSYGHAYGFSICSLMEMQWLDST
                     SVHSGEFFHGPFEVTDKDTNFILLMSIGRTRALDERAKRFLDKYAERVEIVDAKELGL
                     DMISDEVSEFFNPILFYSILSEYRSALADARNHDLDVRRYMGKVEY"
     gene            3421..4236
                     /locus_tag="LP493_002735"
     CDS             3421..4236
                     /locus_tag="LP493_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HBL2134835.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKKIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAID
                     KVDFGFFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEE
                     PVDTMAAGDSFLTAFLLYFLEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            4304..5014
                     /locus_tag="LP493_002736"
     CDS             4304..5014
                     /locus_tag="LP493_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2134836.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYVMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            5050..>6176
                     /locus_tag="LP493_002737"
     CDS             5050..>6176
                     /locus_tag="LP493_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBL2134837.1"
                     /translation="MKQVLRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKIL
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIK"
BASE COUNT         2096 a          938 c         1257 g         1885 t
ORIGIN      
        1 aaaatgatac gcagttcgca attcttcgtt gtagcttaac agctcattaa cgatttctgt
       61 ttgactaatt ggtcgtttaa acagtcgatg ataatgccgt ttgagtgcct cccatgtcgt
      121 ggaatctttg agtaagagtt tccaatatcg cttgagccga cggtacttct tctgattttc
      181 agagtgtgag gttcgaaaac gattcatgat ctggacacgt aattgattga agctgcgatt
      241 gatgtgttgg acaatatgaa agcggtcagt tacgatctcc gcatttggaa agaccgtttt
      301 aagcaactga caatagctgg cattcatgtc catcactagg tacttgacct ttaaacgggc
      361 ctttctagga aagcgcagga agtattgagt tagtttgtaa agtctgcgat cttcaagggt
      421 cgtaaatagc tgattggttg tcccatcaac acaaataaaa ctcatggaac cagaagtggc
      481 aacattgtgt acttttcttt gcaatcttgt gtacaaaact attgcaaaac acagcgcata
      541 agaatcctta caaaacagta gatgaagcaa cccaattaga tcttgttata gttgttaatc
      601 agctcttaac gggttacgat tcaaaatggg tcaacaccct atacttagat aagtcacttg
      661 aatatcagaa cataattcag gctttttcac gcacaaatcg tcttaatggt cctgaaaaac
      721 cgttcggaac cattcgttat tatcgtaaag cacatacgat ggaacagaac attgaagagg
      781 ctattgagtt atactcaggc aaacaagcaa aagggttatt tgttgaaaaa ttatataata
      841 acttagaaaa gttgaacgat atattcgaag aaattaagtc cgtatttaat atttctggca
      901 tagaaaactt cagtcattta ccggaggttc caggggaaat taagcaattt gtaaatcttt
      961 ataatcaact aatccattgt tatgaatcag cgatgataca gggattcaca tgggcaaaat
     1021 cgacttatga aatccaggat tatgaaccta taacagtagt aatcacagaa tatgaattta
     1081 atatcttggc acaacgttac agcgagatag agagagaacc tagagacgga aatgatagta
     1141 tagcgtatga cattgattac caattacctg aaggtagtcg tagtcgtatt aattatgagt
     1201 atttaaacac aaacttcaaa aaatacatga atataaaaga agaacgtgat tcgaatttaa
     1261 ttcaatcatt gttaaacgac ttacatcgca catttgcgca attaccagtg gagttacagc
     1321 catatgctga gatgattcta aatgatgtaa ataatgggga attagttatc aaagaaggat
     1381 gggaatttac tgattacctc aatgaatatc agcttagtga agaggacgat tttatccaag
     1441 atttagtgga ttcaaccaat attaatgagg cattattacg tgagatgttg gatttacgct
     1501 taaccgaggt aaacattaat gaatatagtc gatttgataa attaaaatca agtgttaacg
     1561 taggtcattt cagtggatat atcgagaaaa atttaggtaa aatggtaata ccaatcaagg
     1621 taaatatgct aattgacaga ttattgcgtg catttttatt agaagatgta ttcgatgtta
     1681 cagagtacat aaagaattac tttaactaga gtacacctac atcttatagt acataaaaaa
     1741 attcatcttt tttagtttaa taattcacca aaaaggtgag taatgccatt tttgaaaatt
     1801 gagcttgttt tatgtctaca tctgtatccg tatataatcc aaaggattat aaactcagaa
     1861 gagtctttat tttttctgaa tataactact gtatcaaaaa caatcgatta tgagacaaaa
     1921 caaaatgacc tcttttattt aagaaaggag gtcatttttt gtatcataaa ttgtattaaa
     1981 atcaatgtat cactttttaa tcaattttaa gaccataaat tgcgtactaa aagaaattct
     2041 gcaattcaaa ataaagcatt ttaagccatt ttcaaattta agtgcaccca tctacccgtc
     2101 aaatcacttt attttccact ccagtagttt cctaattcaa ctgtgtgcaa aacgatttct
     2161 tctaaacaaa tcaagacaaa cttataaacc ttcatcccag caccataatt atttaaatca
     2221 taggcatttt tcgaaattag tatatgtact caagtttcac tgcagattat ttatattttt
     2281 tagagaaata aatttttcct attgacaaac acaaagaaag cggatacaat acaattatgt
     2341 cacatgacgt tatatgacgt tatgtaatat ctttacattt aatcagttac ttttattttg
     2401 gataaaatta acatttttaa aattttaagg aggaaatgtt gatggatgta gcaaaaacgg
     2461 ttaacgcaat tgtagaaaaa aatgatggag agatttctgg aatttatttg gtggcttgtg
     2521 gcggttcgct ggtagatatg tatgtctcag attattttct taaagccgaa gcatcgaagt
     2581 gtattacagg cttatataca gcgaacgaat ttaaccatgt aaccccaaag caattagatg
     2641 ataaatctgt tgtcattcta tgttctcatg gaggaaatac agcagaaacg gtaaaagcag
     2701 gagaagtcgc tcaagctaga ggagctgtga ctgttggtct gactcataat aaaactgcgg
     2761 atttattaaa ggtttctgat catagtttcc tttacgaatg gggagatgat gcaaaaatag
     2821 tcaataatcc tatggccatc attcttgatt taactgtatc tttggtcaat gttaccgaaa
     2881 catttgaaca ttacggtaaa ttcagagaag gcatgaaggt tatcgatacc gtaattgaaa
     2941 atggcattaa gcaggtgcag gatcgtatta aagtgtttgc tgataagtac aaagatgaaa
     3001 caatgtttta tatcttaggt agtggaccat catatggaca tgcttatggt ttttcaattt
     3061 gctctttgat ggaaatgcaa tggcttgatt caacttctgt tcattctgga gaattcttcc
     3121 atggaccttt tgaagtaaca gacaaagata cgaattttat tctcttgatg agcattggac
     3181 gcactcgtgc tttagatgaa cgggcaaaac gattccttga taaatatgca gaaagagtag
     3241 aaatcgttga tgcaaaggaa ctaggattgg atatgatatc agatgaagtt tctgaattct
     3301 tcaatcccat tttattctac agtattcttt cagaatatcg ttcagcttta gcagatgcac
     3361 gcaatcatga tttagatgtt cgtcgctata tggggaaagt ggagtactag gaggattaaa
     3421 atgaaggtat taggcttagg tgataacgtc gtcgataaat atgaaaatct gggaattatg
     3481 tatcctggag gaaattcatt gaattttgca gtttttgcaa aaaaactggg acatgaaagt
     3541 agctttatgg gagtttttgg ctcagatgag gaggcagctc atgttttatc agcaataaaa
     3601 aaaataggac tggacaacag tcactctcgc tttgaaaaag gcgagaatgg ctgtgccaga
     3661 gtgaagattg atgagggcga ccggattttc cttggcagca attcgggagg tgttactcgt
     3721 gaatacccga ttcagcttac tgaagaagac agagaatatt taaaccagtt tgaattgatt
     3781 catatgggat tatatagcca tgtcaatcat ctattagaag agttacaaaa tgtttctgga
     3841 aagatttctt atgatttttc tgacgacttt acggaagaag aggttcagcg ggcaattgat
     3901 aaagttgatt ttggcttctt ttctatagaa gacttttccg atgaagaagt aaagcagttt
     3961 ttgatgaagc atttttgtga gcgaaatgat gtattgattg caacccgagg agaaaaaacg
     4021 gctattggtt atgatggagc aaagttttat gaagtgaacc ccgtgctaga agaaccagtt
     4081 gatacaatgg cagcgggaga ttctttctta acagctttcc tactttattt tctcgaaggg
     4141 gacgatatag tcaccgcgat gaaaaagggg aatgaatttg ctgggaagtc ttgtctggtt
     4201 gacggttcgt tcggctttgg tattcattac gattgagctt gttttaaatt cctgcatttg
     4261 ataacctaaa gaaagaaatc ccggtaaagt ggaggttaaa aaaatgctgg atacaaatgc
     4321 acaattacca ttgtacttac aattaaaaga aatattaaaa aataaaatca atacagggga
     4381 gtatcccgag aatacgaaaa ttcccgctga atcagagctg atagaaagtt atgaggtcag
     4441 ccgaatcaca gtgagaaaag cagtagaaga actggtagaa gaagggtacc tacttaaaaa
     4501 acaagggaaa ggaacttttg tcaaccggca taaagttttt cgtaaaattg aatatgttat
     4561 gggtttcagt gagagttgta aatctaatgg ttttacaccg actagcattg ttttggaacg
     4621 caagatcatt ccagcaactg aagggatggc aaaaaaactc gatatcgctc aaggtgatga
     4681 tgttttatat atccagagaa agcgaatggc ggataacatc cccattatgt tagaaaacaa
     4741 ttatttttct tatgaaagat atagtttctt aatggaggaa gagctgactg attctttgta
     4801 tgaagtactt aaagtccaag gtaccttagc catcaatcct ggggaaactg cacttgaaat
     4861 tgtcacagct gatgaccaaa ttgccaaaat aatggaagta gctgttggga cgcccttttt
     4921 ctttatggat actttaatca acgatcaaaa caacatacca attcatgtag gtaatcaata
     4981 ttacctggga gaagtatatc gtttttactt atgatttcct gttttgattt caaggagtag
     5041 attttattta tgaagcaagt attgcggtca aaaatgattt ttgatggaga gcagccacct
     5101 ttcaaaggtt atattgtaat caatgaaggg atcattgaaa aggtggaaaa caactggaat
     5161 tacagtgatc tattaaatga aaacacggaa ttaattgctt atgatgatca attcgttatg
     5221 ccagcaattc atgataatca tgtatttttc agtggttatt tggctatgaa tgctggcata
     5281 gatttaagcg atacatcttc agctaacgag gctgtagagc gtattaaagc tgtaatgaac
     5341 cataaaaaag cagatgaacc aatttatgct catggctggg atgctgccct gtggaaaact
     5401 gacccatcag aagagctatt gaatgaaata aaccactttg gtccaatcac agcgatcgac
     5461 aaaaatcgca gccattgttg gatgaatgct attgctaagc agacttatgg ttttacagaa
     5521 aaagaaacca gtgctgaaag tcgagtatta ttaattaagg aaatgctagc aaacaaaaag
     5581 cttttagcag aggtttacgc tgaatttgaa gcattactgc tttcaaaagg tgttatatca
     5641 atgaaagaaa tcgtttttga tgacgcagaa tttctttcta atatacctca gaggaaaata
     5701 cttagtaacc tatatgtgca ggcagtccaa gaacctctac agcatgaact tctatatgag
     5761 tataaggaaa aagttttccc tgaaaaggtc cgctttggtg gagtgaagat catggtagat
     5821 ggtgttgttg cggatagaag tggagatatt tacggtgttt atcagtcagg agtagcttca
     5881 cccgagattg actatgaggc aattaaagca gaagttgctg cattcaatga agtagagatt
     5941 ccttgctgtt tgacaacgga aggagataaa gcgggttata aagctgcgtc aattcttgtc
     6001 gaatttggaa agcggttacc tgaaggcgtt tttaattcga ttagtgattt ggaaatggtt
     6061 actcaaaaga cagcagaaaa aatgaacgaa ggacaagtag tagcagaggt atatccacaa
     6121 attctcggct tgaatcaaac gttagaagag gcttacatgt caactgttat aaaaaa
//
LOCUS       DAFENC010000090         6173 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.095, whole genome shotgun sequence.
ACCESSION   DAFENC010000090
VERSION     DAFENC010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.095"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            725..811
                     /locus_tag="LP493_002738"
     CDS             725..811
                     /locus_tag="LP493_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HBL2134838.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="LP493_002739"
     CDS             complement(932..1621)
                     /locus_tag="LP493_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134839.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1628..1906)
                     /locus_tag="LP493_002740"
     CDS             complement(1628..1906)
                     /locus_tag="LP493_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134840.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(1866..2780)
                     /locus_tag="LP493_002741"
     CDS             complement(1866..2780)
                     /locus_tag="LP493_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBL2134841.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="LP493_002742"
     CDS             complement(2762..3142)
                     /locus_tag="LP493_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HBL2134842.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="LP493_002743"
     CDS             complement(3592..3879)
                     /locus_tag="LP493_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBL2134843.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="LP493_002744"
     CDS             complement(3899..4123)
                     /locus_tag="LP493_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HBL2134844.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4578..4748)
                     /locus_tag="LP493_002745"
     CDS             complement(4578..4748)
                     /locus_tag="LP493_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134845.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4763..5296)
                     /locus_tag="LP493_002746"
     CDS             complement(4763..5296)
                     /locus_tag="LP493_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBL2134846.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5317..6159)
                     /locus_tag="LP493_002747"
     CDS             complement(5317..6159)
                     /locus_tag="LP493_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBL2134847.1"
                     /translation="MREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEKILSL
                     RFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQF
                     NELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQEL
                     TAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALALADKQ
                     KEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLLSDLD
                     NLFQ"
BASE COUNT         1633 a         1151 c         1042 g         2347 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatgattaac gtcataaaaa gtagttttga attcataatc gtttaaataa
     4261 aattataaga tcagttattt aaacagctag tagacataat gtgtatacta ccaagtaacg
     4321 cctgtaccaa gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct
     4381 ctttttaagg cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg
     4441 tcatttttta aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata
     4501 ttcatttatt attcttttct aaggttaata ataggataat ctctttcaga aagactgctc
     4561 gtacgagcag tcttttctta tttatcaagt ttttctacaa atacttcctc attttgactg
     4621 ttgtagtaat taggattgag ttttagttcc ccttttttat ttcctttgtt ggccactgat
     4681 aataacattg ggctaaagct taatattcct agtaggatag aaccgaatag caagtgtttt
     4741 tttgtcataa gtatttcctt cttcatttcc atagctgcca ccattttttc caattctttg
     4801 tttgttcgtc cattgtttct gttgcttcag aaagagtcgt tgaactattc tctgaagact
     4861 cttccgtata agtcaactgc agttgctcct gaagtttttc gatttgttgg ttggcttgca
     4921 gggtgagttg ttgttgctgg tcgagtagtt tttgtatatg agaattattt tgctctttga
     4981 gggcaagttg ttctcgtaaa aattcatttt cttcacgcaa ctgatctagc aacttgtttg
     5041 caaccacgtt tttgtttggt atataagcat ttttatcgtt gttttgttca tgtttatgca
     5101 acttatctag caacctttga ttgtctaagt tgcgagcaag ttgcaatact ccagaacgca
     5161 atacaacctt ataaccacgc tcatttttag ctatcatgga agaatctaat ttttggatat
     5221 gtttcgatat tgcttgccta ctcatcttaa aaagatctga caattccttt attgtaaagg
     5281 tttcttgtgg ttgcatactg gttgcctcct aggttgctac tggaataaat tatctaaatc
     5341 agataataaa ctttttttct ctttttccga aagtgcggac tctgtttgtt tttcaagagc
     5401 ttttttctct ttttctagtt gtttgatttg ttggaggagt tcaagttctc gtttcttctg
     5461 tttgattttt tcgttaattg ttgtagcggg ttcttcgtat tctttttgtt tatcagctaa
     5521 agccaatgct ttattttggt cttctttggt tggtgcatgt ttgttaaagt cgtctgcttt
     5581 tttgatctca ggtttgaacg taaattgata gccaataaca ggttttcccc gtccttttcc
     5641 gtatttcttt ttgattgtta gtcctttgaa gattgcagtt agttcttgac gtataggttt
     5701 tataactcgt ttatctatat caggttgctt ataactttta ggaatatcta ataattcaag
     5761 aaagtcttct ttggagaaat atgcgaaacc tttggttctg tattgcttta acagacgaaa
     5821 catagtcttt gcatagccac tttgtagctc gttgaattgt tgtaaagaat agcgtaccca
     5881 ctcgtctaaa ttatttaaca aaggcagtgc tttttcgtaa attcgtatat ctacgtaagg
     5941 attttctacg tccccgttga ttttaaattc tgtaaacatt acaaacatat cgtaagaaag
     6001 cccagactca cttctacgac caaagcgtaa agataagatt ttttcataag ttgcttttaa
     6061 atcttctaca aatcgtacat ttgcagttgc tttgtagtta cttaaatctt ttagttggtc
     6121 aaacgtaaaa cgaactgtct tatccccttt ttcacgcatt ctagacacga tgg
//
LOCUS       DAFENC010000091         6065 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.096, whole genome shotgun sequence.
ACCESSION   DAFENC010000091
VERSION     DAFENC010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6065
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.096"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            832..1566
                     /locus_tag="LP493_002748"
     CDS             832..1566
                     /locus_tag="LP493_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBL2134848.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSERELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            1582..2751
                     /locus_tag="LP493_002749"
     CDS             1582..2751
                     /locus_tag="LP493_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBL2134849.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            2767..3762
                     /gene="lacD"
                     /locus_tag="LP493_002750"
     CDS             2767..3762
                     /gene="lacD"
                     /locus_tag="LP493_002750"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBL2134850.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYEEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            3841..4767
                     /locus_tag="LP493_002751"
     CDS             3841..4767
                     /locus_tag="LP493_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HBL2134851.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     LSKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            4786..6036
                     /locus_tag="LP493_002752"
     CDS             4786..6036
                     /locus_tag="LP493_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBL2134852.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDVNRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
BASE COUNT         2025 a          997 c         1246 g         1797 t
ORIGIN      
        1 attggcgcag cgaatccttg ataatgagct cggatgtgct aacgctagcg aggcagtcta
       61 actttaactg ttagctcctg ccgaagatcg tcacatccga ggaggctcat tgtcaaggac
      121 aatcggaata gcatacggaa agaagttctg caccttataa aatttgtcaa aaaaactgtt
      181 gccattccaa agtttgaaaa atgctatttc gaggtagaag gatattatat aagcacggtt
      241 gactaaacga agtgataata aaaaaagtta ttcaagaata agaaaaatta tgatacgaat
      301 tcagataaac tggagaatac agagaccttt aaaagggata agaaacaaca taaattcctc
      361 ttaagagaga acgaaaggac aaagccagca acttgataca cgagctagta ttagaggaat
      421 ttattctcat agactccctt ttgaatacgt ttcaacttta attttcatgt tcataaatga
      481 tttgaaacca aagcaaatgc gttgcacttt tcctccgtct tccgaaaatc gttcaattca
      541 ctggtaagta gtcatttgat agtttgaggc aaattgttga ttgatgaagg gtaggagcta
      601 aaaaaagata ccagttgaag agagaaaaag aaaaaaatag agggtgttct tgaatgaaaa
      661 aagttggaaa attatttttc atttcctttt attcctatta aagtcagtga tgtcaatcat
      721 attaacaaga ctaaaaatga aaataaaaaa aagattgttc ttagtattga ctcataaaaa
      781 ataccactac tatacttaca ttgtggttat agccagttag gagagacatc gatgcaaaat
      841 acctttcaat caaaatcact ttattatcag ctggtagaaa tattgaaaca acgaatcgaa
      901 aacagtatgg tcgctcatga caagctgcca tcagaaagag agttgaccag tttttatggc
      961 gttagtcgca cgacggtgcg actagcattg caagaactgg aaaaaatggg ctacatttat
     1021 cgacaacatg gaaaaggaac ctttgtttcg gaattaagga caaatgcgac tgatctagct
     1081 ggcgcatata gttttaccga acaaatgcgg gcaatgggca aacatcctga aaccaagata
     1141 ttggccttca agaagattga agcaactaaa tatttagcga gtcatctgaa tgttcaacta
     1201 ggtgagcctt tatttcaatt agaccgattg cgcttagctg atgatttgcc aatgatgatc
     1261 gagaaatcct atttgccagt gaagctattt atgtcccttt ctcaagaaat tctatttctg
     1321 aaacctttat ataatttgtt ttcagagaat ttcaatcaaa tcgtacggtt ggctgacgag
     1381 gaattttatg ccagcattgt ccagaaagaa gatagtgagt tgctaaatat tccagaagga
     1441 tcaccagtgc tccatttagt tcgctcaacc tataatctcg agaacgaagt gattgaattt
     1501 acattaagtg tagcgcgggc tgataaattt cattataaga tcaggcatct gcgttccact
     1561 aactgaattg gaggaaagaa aatgtttatg ttctcaaaag aagaactacg aaagctagga
     1621 gcagaaaata ctacccgaga aattcgacag caaccggaac tgtggcatga gacgtttgac
     1681 cgttatcaag aaacagttgc agatttagat cgtttgttta cggatgcgaa acaacatgct
     1741 ggagagcgac caatccgagt catttttaca ggggccggaa cctcgcaata tgtgggagat
     1801 acactaattc cgtttcttac tagtcaagga aatacgaacc agtttatttt tcaaagtatt
     1861 ggttcgaccg atatcgttgc tacgccaaaa gaatacctga ttcctgatga gacaacgatc
     1921 ttggtctcat ttgcccgtag tggaaatagt ccagaaagtc tagccgcagt taagatggcc
     1981 aatcagctgg tcaacaagat ctatcatatc gtgatcacct gtgcaccaga cggattattg
     2041 gctacacaaa tgcctacaaa aaaagaaaat ctagttttac taatgccaaa caaagccaat
     2101 gacgctggtt ttgctatgac aagcagtttc agctgtatga cgctgactgc gctacttatt
     2161 tttgatcaag caagcaatca gcaaaaagaa agatatgttc atcaattaag ccgactagga
     2221 gaagaagtca tccaacgaga atcagagatc caagggtatc tggcatcaga ctttcatcgc
     2281 atcatttact taggttcggg aagcttaggc ggattgacta gagaagcgca attaaaagtt
     2341 ctcgagttaa ctgctggaaa aatcgcaacc gtatttgata catctttagg attcagacat
     2401 ggtcccaaat cttttgtcaa tgagcaaaca ttggttttcc tgtttgtcag caatgactca
     2461 tatacgcaga aatacgatgt agacatgctg gaagaaatca aaaatgacgg tattgcccaa
     2521 cgcgttgttg gaattggtca aaagggttca ttgtttagtg gtgattcctt tgaattagtt
     2581 gcagattcgt tactgccgga tggctatctt gctttagcag atatcatggt agcccaaacg
     2641 atcgcattac tttgttcggt gaaggttggt aatacaccag atacaccatc gccaagtgga
     2701 acagtcaatc gtgtggtcaa aggcgtaacg atttatccat atgaaaaata ggaaagagtg
     2761 tgaagcatgt tagaatggtc ggaaaataaa agacaagcaa tggaacgtct atcgacgcca
     2821 gaaggcatta ttaccgcttt ggcgatcgat cagcgaggcg cgctgaagaa aatgatgtcg
     2881 gctttaggga tggaagcgac aaaggaaaaa attgagcagt ttaaaacact aatttcccaa
     2941 gaattgactc cttatgcctc agcaatttta ttggatcctg aatacggact gcctgctgca
     3001 cagaagcgtg cagcagcgag cggtctgctg ttggcatatg aaaaaactgg ttatgatcaa
     3061 accgtacccg gccgcttgcc ggatctgctg tcggactgtt cagttctgcg attgaaagag
     3121 ttaggtgcgg atgcggtgaa atttttactg tattacgatt atgaagaagc agaggaaatc
     3181 aatcggcaaa agcaagtttt tgttgaacga attggaagcg aatgcatggc tgaaggactg
     3241 ccattttatt tagagttatt gtcatatgat gctaaaaatg tagatacgaa atcgctttcc
     3301 tatgccaaag caaaaccgcg caaagtgatc gaaatgatga aagaattctc gaaaacccag
     3361 tataaagtag atgtcttaaa ggttgaagta ccagtaaaca tgtcatttgt tgaaggaaat
     3421 gcaacagggg agatcgccta tacacgtcaa gaagctgccg cttattttaa agaacaaagc
     3481 gatgcaacag atttgccgta tatcttctta agtgctgggg tatcagcggc attattcatg
     3541 gagacattgc gttttgccaa acatgctggg gcacgattca acggtgtact ctgtggcaga
     3601 gcaacttgga aagatgcagt cgctcctttc gttgaaaaag gagaagcggc aactttagaa
     3661 tggctgacag aacaagggac acaaaacatt cgtcaattga atgaagtgat aagagaaact
     3721 gccatcccat ggtatgagaa agtaagtgaa agcacttgtt aatgtttcta atatattagt
     3781 agtgataaga gatatgtgtg attataattt atcattattg aaactgggag gatattttat
     3841 atgaataaaa gattgttaga ttattcagct tcagattttt tgaaagctaa gccgatggaa
     3901 ttaaagcagg caattttggc ttctgaaggt agaacaatta tggcagaaaa tgtgccaagt
     3961 agctgtcctt acatgggaaa atcagtgaca aatgcagaat tggagagagc tgctggagct
     4021 gatttaattt tgtttaatgc actagatctt tttaatcctc aaatttcagg tgtaccttta
     4081 actctaaaag agaatccaat aatctggatt aaaaaagctt taggaagagc tattggtgta
     4141 aatttagaac ctgtagacaa agaagttttg atgagtgaaa atcgaactga aatttcaagt
     4201 ggtagaatcg tttctcctga gactttaaaa aaggcaaatg aattaggctt taattttatt
     4261 tgtttaactg gaaatccagg aacaggagta tctaatagaa ctattgagaa agcaataaca
     4321 ttatccaaat caatttttaa tggattaatt atcgctggaa aaatgcatgg tgctggtgtt
     4381 gatgaaccaa ttatgaactt agatatagca aaaagattta ttaaaacagg tgtagatatt
     4441 ttattagttc ctgctccata cactgttccg tatttcatgg aaagtgattt gcgaggaatc
     4501 gttgattata taaaagattt taatagaaat aaatctattg aggaaaaagt tctagtacta
     4561 acggctaatg gaacaagcca agactcttct gaccaagaaa ctattaaaaa aattgcatta
     4621 gcatcaaaag catgtggagc tgatattcaa cacatagggg attctttaaa tggtatttgt
     4681 cttccagaaa atatttttgc tttgggtcaa gcaattcggg gatatcgtca tcaaattatt
     4741 atgttaggaa aatctaatta tcgttaatta aggaggaaat gaaagatgat cgacaaagtt
     4801 caaaaaatag ctgcaaaaat tagtaatcaa agacatctac tagctttaag agacagcatg
     4861 gctgcagtta tgccattaat cattattggt tcctttttta tgttattagc aaatttcccg
     4921 atagaaggat ttacaaaatg gttatctgaa attggagtac aatccttttt gaacaaagca
     4981 tcagattcaa catttggtat tattggatta gctgttacct actctttggg acacaatcta
     5041 gcaaagactt atggtgtaga ctcattatca gcaggattat tatctttgag tggatatgtt
     5101 ttacttacac ctttattgga tgcagatggt tctataggat ttccaacaaa atactttggt
     5161 acctcgggtc tttttgttgg tattattgta gcacttgtat ctacagaaat tttccggtgg
     5221 tttgtactta aaaatattac aattaaaatg ccggcaagcg ttccaccaaa tgtaagccga
     5281 gctttcgttg ctattattcc tggctttttt gtcgttctac tatggtttat tgttgttgta
     5341 atttgttata aacttggaat tgaaaatgtt catgctctta ttgcagatac actcgcaaaa
     5401 ccactatctt tactgacgaa aactttacca ggaattatat tggttatact tattcaatgt
     5461 ttcttttgga tgtttggtat tcatggtgca caggtaacgg ggccaataat tgaaccgtta
     5521 ttattgcaaa actctgatgt aaatagaatt gcttatcaag ctggaaaaga acttcctaac
     5581 attataactt atgaattctt atataacttt gttttttctg gtggtgcagg ttgtttattt
     5641 gcacttgcca ttttaacatt tttcttttca aagagtcagg aaaataaaac tttaggtaag
     5701 ttatcaatcg ctccagtaag ttttcaagta gcagagcccc ttctatttgg gtttccaact
     5761 atattaaata taaaaatgtt aattccattt gtaactgcac cagtagtaac aacattaatt
     5821 acttattttt caatgagtat gggattagtt gcaaaacctg taggagcaac aatcccatgg
     5881 acaactccac cgataattgc cggattttta gcttctggtg gacgaataag tggtgcagtg
     5941 attcaagtaa taacaattgc aataaatgtt ttgatatact atccattctt taaattagat
     6001 gataatgcca agctaaaaag cgaaaaaaat gattagaact acctatatgt ttctaactgt
     6061 agtta
//
LOCUS       DAFENC010000092         6029 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.097, whole genome shotgun sequence.
ACCESSION   DAFENC010000092
VERSION     DAFENC010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6029
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.097"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(68..370)
                     /locus_tag="LP493_002753"
     CDS             complement(68..370)
                     /locus_tag="LP493_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134853.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(590..956)
                     /gene="ssrA"
                     /locus_tag="LP493_002754"
     tmRNA           complement(590..956)
                     /gene="ssrA"
                     /locus_tag="LP493_002754"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1127..1900)
                     /locus_tag="LP493_002755"
     CDS             complement(1127..1900)
                     /locus_tag="LP493_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBL2134854.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            2044..2394
                     /locus_tag="LP493_002756"
     CDS             2044..2394
                     /locus_tag="LP493_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBL2134855.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2375..3091
                     /locus_tag="LP493_002757"
     CDS             2375..3091
                     /locus_tag="LP493_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2134856.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            3091..4539
                     /locus_tag="LP493_002758"
     CDS             3091..4539
                     /locus_tag="LP493_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL2134857.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4610..5119)
                     /locus_tag="LP493_002759"
     CDS             complement(4610..5119)
                     /locus_tag="LP493_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134858.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(5109..5834)
                     /locus_tag="LP493_002760"
     CDS             complement(5109..5834)
                     /locus_tag="LP493_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134859.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
BASE COUNT         2052 a         1050 c         1170 g         1757 t
ORIGIN      
        1 aaaaatatcc cttttataag tatggtgata aaatccgttc cgggctacct tttttaggta
       61 gcctacttta atctttatac ctttctggat caacgaaagt atacttcaaa tagtcataac
      121 gccgatgatc gctccgtgcg tctggcacat cagtcacgat atcaaacaaa aaatacacat
      181 ctttcttcat tctggttttt gttgccggaa ttttaaagta gttcttatta gagtaataga
      241 gattgattaa taagctatct tcgattgcta aaaagaaaac ttctgaatcc cacaccttat
      301 aaaaatcttt gacaaatcta ttcgaaggat caaatttaaa ccataattgt gtttttcctt
      361 ccatcaacat aatgttcacc tcaaaaagag tatacgaact aatgttcttt ttgtaaagta
      421 ggaatatcat tgataatatg gatggaacat atatattaaa aagtgttctt tttgaatgct
      481 attttgaatg ccattttcat tcatttaacg aaaatctgcg aaaataaaaa atgctcaaac
      541 ccttataaaa taaggattta agcatctagc gaaatctgct gaaatctcac aatggagacg
      601 gcgggagtcg aacccgcgtc caaacacatc gccacttaaa aatctacgtt catagtcaac
      661 tcatttaagg attcacttta cagcttgccg agtgacaggc attctgtatc gctagtctga
      721 tgttctcttt ttcaacttac agacggaaag ttgaaacgta tcccactaaa gttaggaccc
      781 ttactcgagc acatgggcga tgccgagagg atctacgcta actgttttta ggcagctaaa
      841 gcgtaagagt tgttttcgtt tttagcagtt atatttaact gtaacgtttt tacgtagacg
      901 taacctacga aacgcaattc aagctcgact gtgcctgtcg aatccgtaac gtccccgtta
      961 gctaacaagg gttacgtgta tttttcatac aaaattagta tagcatatat tgggataaat
     1021 tcaataaaaa agcgaatcat atcccattat ttatataata actgcccctt tcttaagaaa
     1081 aaataagcga ttttcttaag aaaagaggta gcttcaaaaa aagatcttaa atcagatcaa
     1141 aatacttcaa tgcgtggaca attccgcctt ctgtattttt ctttgtgata aaggtagaaa
     1201 gttcttttaa tccgtcatag gcgttgccca tagcgatttt gttgtcgcaa gcttccaaca
     1261 aggcaaaatc attcggacca tcgccaaatc caaaagtagg aactttttcc agctgaagtt
     1321 ctttttgcag acgtttgaca cctgcccctt ttgagattcc tttcttcact gtatcgatcg
     1381 agtaaggacc attccgataa aaagttagct caggaaaatg ttcgtgatag tattcgtcac
     1441 ctgattgaga taagatcagc aacatattta ctgtgttttc tttaaagcct aaaggatcaa
     1501 tttccggaac atctgaatga atgaagtcgt aagcattgat cattgtttgg ctatgaccgg
     1561 tacaccagat tttctgatcg ttatagtaag aaagttcatg accgttcaac tgtacatgat
     1621 catacatttt ttgacattct tctgaagaaa atgtttgaga atagatttct tcgccgtcta
     1681 ctcgaatgaa agaaccattc atggtgaccg cagaagtaat gcccgcatct tccatgatag
     1741 agtggatttc tgcttctgta cgtcctgtag cgatgacggg gagaacattg ttttctttta
     1801 atgcgttcat agcttttgcc acttcgggtg tgatttttga tttcgcatct agtaatgttc
     1861 catcaagatc aaagaaagtg attgcacgat aatttgacac aaataaaact ccttttttat
     1921 tggaataagt ttatcttaac aaagaatgaa caaaagacaa acctttcgtg aagaattcct
     1981 gaacatattg gttcagtcaa caatttagag tatactataa gaagagaatt taggagggaa
     2041 agaatgattt ttttcagtat tggtatctta ttcttaataa ttggcagtct ttttcggatt
     2101 ctgccctcaa aaggaaatct gcctttttat gggtatcatt cgcctcttgc cgcaaaaaca
     2161 gacgctcatt ggcggctggc tcaaaagaca agcggaaact ggttttttct tatgggctta
     2221 ctgatggcat tgatcggcta ttatttaaag acatctgggc atacgaatta ttttctgatt
     2281 gaaatgcttc tgctagtatt tccaattatg cctattttta ttatgacaga aaagaaatta
     2341 cagaaatatg acctggaaac tggagggaac gataatgaat attttaatga ttgaagataa
     2401 tcaatctgtt tctgaaatga tgcagatgtt tttcttaaat gaaggttggg aagcaacttt
     2461 caagtatgat ggaaaagaag ggctcgatgc ctttttagaa aacccacaac attgggatat
     2521 gattacacta gacctgaatt tgcccacact ggacggtatg ctagtaggaa gagagatccg
     2581 caaagtttca agtactgtgc cgattatcat gctgacagct agagattctg aaagcgatca
     2641 ggtgatcggc ttagagatgg gggcagatga ttatgtcaca aaacctttca gtcctctgac
     2701 gcttattgct cgaatgaaag ctttgcatcg ccgtagtgag ttggcagaag caagagaaga
     2761 agcagtagtt tcagatgatc attttgatat cgagactagt catttcaaga tgaatacgaa
     2821 aacacgagaa gcgtatctgg acaaccggcc aattgaagga ctgacgccta aagagttcga
     2881 tctattgttt actttagcaa aaaaaccacg tcaagtattc tctcgggagc agttgcttga
     2941 attagtctgg gattatcagt actttggtga tgaacggaca gtggacgccc atatcaagaa
     3001 attacgacaa aaaatcgaaa aggtcggacc acaagtcatc caaactgttt ggggagtcgg
     3061 ctacaaattc gatgattctg gtgttgccta atgcgttatt tgtatcagca actcttagct
     3121 ttctgcggaa tggtcgcgtt gatcttattg atcgttggag tttcttttac acaactgaca
     3181 aaacaaacga ttgaagaaaa caattaccag caactgtttg gatatgctga atcagttgaa
     3241 aagacaacgc aaacctatgc cgatacgctc ccgcagttta gtcaagatca ggcgtttcaa
     3301 aatgcattgc tgctgacaga gcaagtactg acagaacaaa atgtgaactt tatatttatc
     3361 gataaaaacg aacgtgtcat ttatccgact aatacagctt tactgaattt taccttaaca
     3421 gctgatcaat ggaaaaatct gaggaatgga cgtcaagaaa aattcacatc gaataaaaat
     3481 attttaggac aagcacaggc gacctcttac gcacttgtgc catttaattt gaatcatgaa
     3541 ttctatggag cacttgtagt tagtcaacct gcgcgaaata tcgataacag cgttcgtcca
     3601 attacactga acctgttcaa aggatttatt ttttccagta tcgttgcagt tattgccagc
     3661 tatgcttttg cagcattcca agttaagcgt atcaatcggt taaggaatgc gacgaaagaa
     3721 gtgacgaatg gtaattttga tgtacagctc cccgtacatg acaaagatga atttgatgag
     3781 ttagcagatg atttcaataa aatgacgaat tcattgaaag aatctcaagc agaaattgaa
     3841 gaacaagaaa atcgtcgaag acaatttatg gcagatgctt ctcacgagat gagaacacct
     3901 cttacgacaa tcaacggact tctggaaggg ttagaataca atgcaatccc tgaaaatcag
     3961 cgagaaaacg cgattaaatt gatgaaaaat gaaacagagc gtctgatccg tttggtgaat
     4021 gaaaacttgg attatgaaaa aatccgtacg aatcaaatca gtatggtcat taaaaaattc
     4081 aatggaacag aaacattgaa aaatattgtt gcacagttag aagctaaagc agaagcagca
     4141 ggagatacat tgacattgaa agccgttgat gatattgatg tttacgctga ttatgaccga
     4201 tttgtccaaa tcatggtcaa tattattcaa aacgcgatac agtttactga aaacggccaa
     4261 atcacgatta ctttagaaaa aggctatctt gaaacgatca tcacgattga agatacggga
     4321 attggaatgt ctgaacaaca aatgaaaagt atctgggatc gttattataa agtagatcct
     4381 tcaagaaaaa atacaaaata tggtgaatca ggattaggtt taccaatcgt gcagcaactt
     4441 gtacgcttgc ataaaggaaa attagaagta gaaagcgaac taggaaaagg aacaaaattc
     4501 gctgttcgtt tgcctgacgt agaaatcaaa aaagagtaaa aaacaagcgg tataaaagat
     4561 catgaatcga tcttctatac cgcttgtttt ttactataaa atgattgatt tagcccgcgg
     4621 gctctaaacg atcaatataa ggactttgag caatagtagc atcatgagta aagagtaaga
     4681 taccttgatt ttcttcatga gctaaataag aaagcaagtg gagtagctct tggatctcca
     4741 atacactaag ttcatcaaat gtatcttcaa taacaatatt gtttcgcttg gaaagcaagg
     4801 catgaagtaa ttgcagcttt actttttcaa aagacgtcaa ctcagctgcc gcacaattaa
     4861 gcaaggaagg agagatatca agtttttctt gataggccaa acgatcttgt ttgatttctt
     4921 tttccggtac atccaacagg acatggtctt taagattcag ataaggaaac atcggccaat
     4981 ttttttggat gatcgcaaaa ttatccagtt ttgcaacaag aacctctttt ttcaagtgct
     5041 ccaatatttt atgctgtttt tcgagaggac acaaaataac ggtcaagtgt tcagcatgaa
     5101 tcaaatattc aggtttcatt acgtccaggc ctcctacttt gcaaatgatg gataaaaaaa
     5161 gtgaaaggga atagactaag aatgagacag catccactga gcccaataag agtttgggca
     5221 aatcccttaa gtatatctgt gaaaaaaaga tcattttgga aatcgatggt aaaaaaagtc
     5281 tgttgatcca tcggaattgt aagtccgctt accgaagtca agatatcacg gatatctggc
     5341 agttcagtag tctttaagac aagaaaattg atcctttgaa gaagcgcttc ataaactgac
     5401 tggaagctta cgatccacaa taaaaccaag atacaacaaa gaaagagagg aaagaacagc
     5461 tgccagaaaa taaaaaggaa taatttggtt ttagaaagac cagtcaggtg ccaattgatc
     5521 aattcctgct tgttttgcct gactgaatag taaaagaaaa agataaaaag gaaggcaaat
     5581 agaaaaaata aactgaatat gccttttata taaaatcggc tagctaattc taaagccgga
     5641 agaagctctg tagatgcaga agcgccaata aatgaaagcc gatcttggac ttgattggct
     5701 aaagccgatt gcaaatggta aagagtcagg catgctatca ataaaaaagc agaaaagctt
     5761 gaaaataaac aatagagtat tgtctgcttt ttgtaataaa ttaatcgagc agtagcatag
     5821 cggattattt tcatactttt cacctctata aaaagtatag aaaatgaata tgaataaagt
     5881 atgaaattcc tttagtgaaa tcacgaatta aaaccagaaa atattttgta aaaagcaaga
     5941 ggttgtgaag aagctgccct attctattac cgtagatgca agcttttgaa cactgtttat
     6001 tcgaaaagag gagcagcgac aataatttt
//
LOCUS       DAFENC010000093         5755 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.099, whole genome shotgun sequence.
ACCESSION   DAFENC010000093
VERSION     DAFENC010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5755
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.099"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            312..482
                     /locus_tag="LP493_002761"
     CDS             312..482
                     /locus_tag="LP493_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134860.1"
                     /translation="MKKFIYRVLENDEVVAIFNEQQYAQDFIAYEKTISDKQFEIEKV
                     DIADWLLQPREF"
     gene            496..1098
                     /locus_tag="LP493_002762"
     CDS             496..1098
                     /locus_tag="LP493_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2134861.1"
                     /translation="MAKIGYARVSSKEQNLDRQLKALEGVSKVFSDKLSGQSVERPQL
                     QAMLNYIREGDIVVVTELDRLGRNNKELTELMNQIQIKGATLEVLNLPSMNGIEDENL
                     RRLINNLVIELYKYQAESERKRIKERQAQGIEIAKKKGKFKGRQPKFKENDPRLQHAF
                     DLFLNGCSDKEVEEQTGINRRTFRRYRSRYNVTVDQRKKQ"
     gene            1114..1791
                     /locus_tag="LP493_002763"
                     /pseudo
     CDS             1114..1791
                     /locus_tag="LP493_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
     gene            2102..2266
                     /locus_tag="LP493_002764"
                     /pseudo
     CDS             2102..2266
                     /locus_tag="LP493_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000898188.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
     gene            2303..2599
                     /locus_tag="LP493_002765"
     CDS             2303..2599
                     /locus_tag="LP493_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
                     /protein_id="HBL2134862.1"
                     /translation="MSKGFLEPALFNQERNVLDSEIKNLTTEKTNLVTNSASGVLRAN
                     EIKDLINYVSADNFNGDYTEELFEEFVVNIIVNSRDELTFNLKCGLSLKEKVVR"
     gene            2600..3016
                     /locus_tag="LP493_002766"
     CDS             2600..3016
                     /locus_tag="LP493_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HBL2134863.1"
                     /translation="MAYIPYGYKIQDGVVTVDEKAAGQVKVFFEKYISGLSLTVAGEQ
                     AGIEKTHSVMGRILKNVNYLGNDTYPAIIDKEIFDKAEEVRDKRAKDLGRVVELAAFT
                     SPPPKERFKMKKADNKMPVDPFERAEYLYSLIESEE"
     gene            3036..4580
                     /locus_tag="LP493_002767"
     CDS             3036..4580
                     /locus_tag="LP493_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018659190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2134864.1"
                     /translation="MVIPARKRVGSTAAKEKIKKLRVAAYCRVSTETEEQNSSYEVQV
                     SHYTEFIKKNNEWEFAGIFADDGISGTNTKKRDEFNRMIAECMDGNIDMVITKSISRF
                     ARNTLDCLQYIRQLKDKNISVYFEKENINTTDAKGEVLLTIMASLAQQESQSLSQNVK
                     LGLQYRYQQGKVQVNHKRFMGYTKDEDGNLTIVPEEAEIIKRIYREYLEGQSLVGIGR
                     ALEKDGILTAAGKPRWRPESVKKILQNEKYIGDALLQKTVTVDFLTKKRVKNEGHVPQ
                     YYVENSHEAIIPKELFLQAQEEIHRRSNIYTGEGKNKRIYSSKYALSAITFCGDCGDI
                     YRRVYWNIHGRKEFVWRCVTRIEQGPEVCKNRTVKEDELYGAVMTAINKLLAGGNNMI
                     KTLEENIHAVIGETTEYQISEINNSLEEKQKELIKLANKGQDYDHLADEIDELRDKRQ
                     ILLVEDASLSGENERINELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEGHFVIAFKS
                     GIEMEI"
     gene            4723..4947
                     /locus_tag="LP493_002768"
     CDS             4723..4947
                     /locus_tag="LP493_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2134865.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGEEIKISNE"
     gene            4962..>5755
                     /locus_tag="LP493_002769"
     CDS             4962..>5755
                     /locus_tag="LP493_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBL2134866.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDENRNNLVVPPGAWGDWVNGGGWLVINGCHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGAEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLY"
BASE COUNT         2054 a          915 c         1226 g         1560 t
ORIGIN      
        1 tatgatacgt gtttgttttt ctgtgctgtt tagtgaatga ttagcagaaa tatagagagt
       61 aagattttaa ttaattatta gggggagaag gagagagtag cccgaaaact tttagttggc
      121 ttggactgaa cgaagtgagg gaaaggctac taaaacgtcg aggggcagtg agagcgaagc
      181 gaacacttga tcttttaagt tgctatcttt ttaaggtcaa tagagtatac ttatttgtcc
      241 taatatggtt ttagcagtat aattgacttg gtgaataggt catttaagtt gggcataata
      301 ggaggagtaa aatgaaaaaa tttatttatc gagttttaga aaatgacgaa gtggtggcta
      361 tttttaatga gcaacaatat gcgcaagatt ttatcgctta cgaaaagaca atttctgata
      421 agcaatttga aattgaaaaa gtagatatag ctgattggtt attgcaaccg agagaatttt
      481 agaggttggt tgaaaatggc taaaattggt tatgcacgtg tcagtagcaa agaacagaac
      541 ttagatagac aactgaaagc gttagagggc gtttctaagg tcttttcaga caaattaagc
      601 ggtcaatcgg tcgaacgccc acaattacaa gctatgctta actatattcg tgaaggggat
      661 atagttgttg ttactgaatt agatcgatta ggacgaaata ataaagaatt aacagaattg
      721 atgaatcaaa ttcaaattaa gggggcaacc ctggaagtct taaatttacc ctcaatgaat
      781 ggtattgaag atgaaaattt aagacggctg attaataatt tagtgattga attgtataag
      841 taccaagcgg aatctgaacg caaacgaatt aaagaacgcc aagcccaagg aattgaaatt
      901 gctaagaaaa aaggaaaatt caaagggcga caacctaaat tcaaagaaaa tgatccacgt
      961 ttacaacacg ctttcgattt atttttgaat ggttgttccg ataaagaagt tgaagaacaa
     1021 actggaatta atcgccgaac gtttagaagg tatcgatcaa gatacaacgt gacagtagat
     1081 caaagaaaaa aacaatgaaa agagggatag ttaatgagta cggttatttt agctgaaaaa
     1141 ccaagccagg cattagccta cgcaagtgct ttaaaacaaa gcaccaaaaa agacggttat
     1201 tttgagatca aagacccact atttacagat gaaacgttta tcacctttgg ttttgggcat
     1261 ttagtcgaat tagcagaacc aggtcattat aacgaaaagt ggcagaactg gaaacttgaa
     1321 tctttgccga tttttcctga tcgatacgat tttgaagttg caaaagataa gggaaagcag
     1381 tttaaaattg ttgctgaact tctcaaaaag gcaaatacaa ttattgtcgc aacagatagc
     1441 gacagagaag gtgaaaatat cgcctggtcg attatccata aagcaaatgc cttttctaaa
     1501 gataaaacgt ataaaagatt atggatcaat agcttagaaa aagatgtgat ccgaagcggt
     1561 tttcaaaatt tgcaaccagg aatgaattac tatccctttt atcaagaagc gcaaacacgc
     1621 caaattgccg attggttgat cggcatgaac gcaagccctt tatatacctt gaatttacaa
     1681 caaaaaggcg tacaaggtac attttcatta ggacgtgtac aaacaccgac tttatatctc
     1741 atttatcaac gccaggaagc aatagaaaac tttaaaaaag aacctttttt cctgaataat
     1801 tcatagtttt actaatagtc tttcctaaca ttgatttaat agtctttaaa gtattctgct
     1861 tcatcaccca ttaggtgatg aaaaaagaac ccctttctga tttagcggac aaatactttg
     1921 acctaatctc agaagatata aaagaaaaaa taataaaata tccgatttat actttgtata
     1981 aagaactaaa gtagttagca aatcatttac agcaaatcac tatgttccac ataccatttt
     2041 acatacttac cttatccacg acacatgttg agatagtatc gaagataaag aaagttgctc
     2101 catgttgttt ttgcgagatg gggaaatcaa agccacattg acaaccatga tgaataagct
     2161 tgctttcagt cataagctaa tcctagaacc acttttcaag tcagttagcc aaatcgatga
     2221 agaaagcgac cgtgaaagaa tggacgctat tgataagcta atggagcaac tattggaaga
     2281 acgcaatacc cttattgcac tgatgtccaa aggtttccta gaacctgctc tttttaatca
     2341 ggaacgaaat gttttagata gtgagattaa aaatcttact accgaaaaaa caaacctggt
     2401 aacgaactct gcgagtgggg ttttgcgagc aaacgagata aaggacctca ttaattatgt
     2461 gtcagcagat aattttaatg gtgactacac ggaagaacta tttgaagaat ttgtagtgaa
     2521 catcattgta aattccaggg atgagctgac attcaatttg aaatgcggtc tttccctgaa
     2581 agaaaaggtg gtgagataaa tggcatatat tccatatgga tacaaaattc aagatggagt
     2641 ggttactgtc gatgaaaagg cagcaggtca agtaaaggta ttctttgaga aatacatatc
     2701 aggactatcc cttacagtgg ctggcgaaca ggcaggtatt gaaaagacac attctgtgat
     2761 ggggcgcatt ttgaaaaacg tcaactacct tggaaatgat acgtatccag caattattga
     2821 taaagagata tttgataaag ctgaagaagt tagagataaa cgtgcaaagg atttaggacg
     2881 agtggtagag cttgccgctt tcacctctcc ccctcccaaa gaacgattca aaatgaaaaa
     2941 ggcagataat aagatgccag tggatccttt tgaacgagca gaatacttat acagtctgat
     3001 agaaagcgag gaataaagtg acagagaaaa atataatggt tattcctgct cgtaaaagag
     3061 taggaagtac agccgcaaaa gaaaagataa agaaacttcg tgttgctgcc tattgccgtg
     3121 tttctacaga aacagaagaa caaaattcta gctatgaggt tcaggtctca cactatacag
     3181 agtttataaa gaaaaataat gaatgggagt ttgctggcat ctttgcagat gatggtatct
     3241 ctggtacgaa cactaaaaag cgtgacgaat ttaatcgcat gattgcagag tgtatggacg
     3301 gtaacatcga catggttatt acaaaatcca tcagccgatt tgcgcgtaac accctagact
     3361 gccttcaata cattagacag ctcaaggata agaacatatc agtttatttt gagaaagaga
     3421 acatcaacac cacggatgcc aaaggtgagg ttttgctgac tattatggca tctttggcac
     3481 agcaggaaag ccagagcctt tcacaaaacg ttaagcttgg gctacagtac cgataccaac
     3541 aaggaaaggt gcaggtcaac cataagcgat ttatgggcta cacgaaagat gaagatggaa
     3601 atttaactat tgtccccgaa gaagctgaga ttatcaaacg catctaccga gaataccttg
     3661 agggtcagag tctagtgggc attggtcgag cccttgaaaa ggatggtatt ttaacagcag
     3721 cgggaaaacc aagatggcga ccagaatcag ttaagaagat acttcaaaac gaaaaataca
     3781 tcggagatgc ccttctgcaa aagactgtca cagtagattt tctgaccaag aaacgagtga
     3841 aaaatgaagg gcatgttccc caatattatg ttgaaaatag ccatgaagcg attattccta
     3901 aagagttatt tttgcaggcg caagaagaaa ttcatcggag aagcaatatc tacacaggag
     3961 aaggcaagaa caaaagaatt tacagtagca agtacgcttt aagtgccatc accttctgtg
     4021 gagattgtgg cgatatttat agacgggtct attggaatat ccacggaaga aaagaatttg
     4081 tctggcgatg cgtgactaga atcgagcaag gtcctgaagt ttgtaagaac cgaaccgtaa
     4141 aagaagatga actttatggt gcagtaatga ctgcgattaa taagctactt gcaggtggga
     4201 acaatatgat aaagacactg gaagagaata ttcatgctgt gattggcgaa accacagaat
     4261 accaaatttc agagattaac aactcactag aggaaaaaca aaaagaacta atcaagctgg
     4321 cgaacaaggg tcaagactat gaccacttag cagatgagat tgatgagctg agagacaagc
     4381 gacagatcct tttagtagaa gatgcctccc tcagtggcga gaacgagcga atcaatgagc
     4441 tgattgaatt tatccgcaag aacaaattcc gcaccttaga atatgatgat aagcttgtaa
     4501 ggaagataat ccagagcgtt acagtctatg aaggccactt cgtcatagcc ttcaaatctg
     4561 gcatcgaaat ggaaatatga aaaccagaag taaatagccc atgactctac agtagagttg
     4621 tgggttttct tttgcttgct gattataata atattttaat aactattgtg tttatcaacc
     4681 aaatggttta taatattctt agcgtaaact tggaggtgct gtatgactac ggcagaaatg
     4741 attaaagaac tgtgtgagca aatgaatata agtgtttccg aacttgctag acgtattggc
     4801 cagactccac agaatttcaa taaaaaatta caacgagaaa cagtaacctt ggatgagttg
     4861 aaggccattg ctgatgtgct aggtgtcaag tttgtgcagg catttatttt accagatgga
     4921 gaagaaataa aaatatctaa cgaataaagg aggatgttta tatggtaggt aatgttattc
     4981 aaatagtaac agagaaatta tcatctttgc cttttataga aggcatcgta ttagggggct
     5041 cacgtgcaag aggcacccat acagaaaatt ctgatataga tatcggaatc tattacaatt
     5101 cagactcatt tgacctgaca gcgattaatc aaattgctac agagttggat gatgagaata
     5161 gaaacaacct tgttgtacct cccggagcgt ggggtgattg ggttaatggc ggtggatggt
     5221 tagttataaa cgggtgtcat gttgacttga tattacgtga tataaaacgg gtggaacaaa
     5281 taatcaaaga tacggagcaa ggaattgtta ctgccaatta tcagaccggg catccccatg
     5341 gttatataag tgctatgtat cgtggagaat tagcgattag taaaatacta tatgctaaga
     5401 acgaaagctt atgcgaatta aaaaagcagg cagaaattta ccctactgct ctaaagaaaa
     5461 gcttgatgaa cttttttata tttgaagctg aattctcttt aatgtttgta aaagcaaatg
     5521 cgggggcaga ggataaatat tatattgcag gccatgtttt tcgtattatt tcatgcttaa
     5581 atcaagtact atttgcatgt aataatgctt attgcattaa cgaaaagaaa gctataaaac
     5641 tgcttgaaac ttttgaatat aaacctgaaa aatatgccga aagagttaat catatttttg
     5701 aagtactcgg tctttctctt tttgaatgct acgacatgac cgagaaactt tataa
//
LOCUS       DAFENC010000094         5339 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.100, whole genome shotgun sequence.
ACCESSION   DAFENC010000094
VERSION     DAFENC010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5339
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.100"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(19..414)
                     /locus_tag="LP493_002770"
     CDS             complement(19..414)
                     /locus_tag="LP493_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134867.1"
                     /translation="MKNKGQIWYIGYIVSLFLIVTILVTDFPKMVDIGLAILFSAVFG
                     VSHVQILHDKMIKNDADYKINVMDERNIIIKEKAGNITNMFNTILLGVATVIFICLDY
                     IIPAIIVGSIIAIQPIILIIISSVLEKKM"
     gene            complement(404..616)
                     /locus_tag="LP493_002771"
     CDS             complement(404..616)
                     /locus_tag="LP493_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2134868.1"
                     /translation="MKNRLEELRKQRGIKQEDLASALEVSRQTIGSLENGRYNPSIIL
                     AFKIARYFQMSIEEIFIYEEESEDEK"
     gene            1688..2290
                     /locus_tag="LP493_002772"
     CDS             1688..2290
                     /locus_tag="LP493_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134869.1"
                     /translation="MEDIILRDRLTDPLKNSLANVIYDILREADKVYSNYNGKVSWVI
                     YSFLIKEFFKEQINNSYELGYHFTVYYEDIIKRLEDLEWYAYYDLLEVFASAKILDKK
                     KREEVNKILESENSGYRLSESNEFIPITDDISIKSINAVSESPFNYAKNHIHKSLTYI
                     SEKENQDYNTVVREAISAVESCLIEFSGLPANKKILWELL"
     gene            2645..2881
                     /locus_tag="LP493_002773"
     CDS             2645..2881
                     /locus_tag="LP493_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HBL2134870.1"
                     /translation="MNIKKRKIREVGNSIVVTLSKESLLQKGLKPGDTIFIDEDKMME
                     AIVKEESKIDLEIDMYVNQALSEYDAAFKELVEK"
     gene            2878..3291
                     /locus_tag="LP493_002774"
     CDS             2878..3291
                     /locus_tag="LP493_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HBL2134871.1"
                     /translation="MIYLSEKDIVKLNVIQIKKYSPRETIGVIDKNALSMAVNQPKQH
                     IFGKDLYPDKFSKAAVLLINLIKKHPFHNANKRTAFLAAYVFLKLNGYSLKMKNQEVV
                     EFVVEIATYQGDFDDLKEATTDILKKNSTKTDSKK"
     gene            3810..4760
                     /locus_tag="LP493_002775"
     CDS             3810..4760
                     /locus_tag="LP493_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HBL2134872.1"
                     /translation="MERNSENKMTGRNPKVFISYSWENKENKEWARELADKLLENGID
                     AYIDQYDLSLGDRLPQFMEQQISDSDYVLIICTPEYKKKANNRTSGVGYEGHIISAEL
                     LSGKNERKFIPIIKEGRASEVLPTFLAGKLGIDLSDSQHYDENLDDLITTIFGVKRKP
                     ALGDIPRHIKGSPLLPIEHNENKDIEILGIITDKVTVPKMDGSRGSALYKIPFRLNRV
                     PSQLWKELFVRNWNSPPRYTTMHRPGIASVVDDEILLNGTTIEEVREYHRETLKLCIE
                     KSNTQEKKILLEEEQKKERENERVRSHKESVQKLADELEF"
     gene            complement(4757..>5339)
                     /locus_tag="LP493_002776"
     CDS             complement(4757..>5339)
                     /locus_tag="LP493_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2134873.1"
                     /translation="SIDQNEQRQIEEMRKFGAEKIFIEKQSGATITHRPIFQEVLDFV
                     RDQDIFIVEAIDRLGRNYDEIIDSVNYLKKKNVRLIITNLPIMAEAIGNPLLDKFIKD
                     LIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANTKDPQRRLVYRSIV
                     QDQENGVAISKIATDYNVTRQTVYRIKKELTIN"
BASE COUNT         1908 a          760 c          902 g         1769 t
ORIGIN      
        1 ttgtatgaac ctttatttct acattttttt ctcaagcaca ctactgataa tgattaaaat
       61 aatcggctgg attgcaatga tacttccgac aataatagct ggaatgatgt agtctaaaca
      121 aataaatata actgttgcca cccctaacag tattgtgtta aacatatttg ttatatttcc
      181 cgctttttct ttgattatga tattccgttc gtccataaca ttgattttgt agtctgcatc
      241 atttttaatc attttatcat gcaaaatttg aacatgagaa acgccaaaaa cggcactgaa
      301 taaaatagca agtccaatat ctaccatttt aggaaaatct gtaaccaaaa ttgtcacaat
      361 caaaaacaac gaaacaatat aaccgatata ccaaatctga cccttatttt tcatcttcac
      421 tttcctcctc atagataaaa atttcttcaa tgctcatttg aaagtacctt gcaattttaa
      481 atgccaatat aatagaggga ttataacgtc cattttctaa agaacctatt gtttgacgag
      541 atacttcaag agcagaagct aaatcttctt gtttaattcc tctttgtttt cgtaattctt
      601 ccaaacgatt tttcacaaca tgctcctttc taaaaaatgg aaagtttact ttcctttcgt
      661 gcttttataa tactcctgcg agcacaaaat gtcaaggaag ctttccatat aaattttgat
      721 tttaatgttt tagttactgt ttttatgaca catgaacaca cttattctta tttcctctta
      781 tctgctatca acagaaaaga aaaagccctg tcaagagccg attagatcaa gccagtcgag
      841 aaacgatgtt agaccaaatt gattttgggt aatgaatgtt tagaacttag tagtcatcca
      901 aaaacgacta ctttttttgt tgaatcgtcc aaggacgatt cgatgctttt gacttgtaag
      961 aacaggattg aatgaaacca tactgttcgc atatttttag tggatgaaca aacaaaatac
     1021 gagagatttt ttgttcgttc atccatggtt ttagaaaaaa gagggacgat tttggaagaa
     1081 gaaaatcgtc tctttttttt cttctttttg tatgacaaaa agaaagatct tttgcccatt
     1141 ttatttttat aaaatgggta ggtggcgttc gcgtaaagca aatcgataca atccaatggt
     1201 tttggcgaat cagatttacc attctaggct tgtttaatac agacatcgat tgttattttg
     1261 agaatttata tccttattgg caatgaaatg gatattctcc ataccaatag aaatcttcaa
     1321 gataattttc ggaaatatat aagagttaat caattatgat catatagtag gtaaaaatta
     1381 ggacagcctt caattatatg ggaaaccaat ataatcaagt aattattcgg gtaacacaaa
     1441 tactagagta ctcatttctt ataactgttt tacacctatt agggatcagt attattaata
     1501 gatctagata aattaatacg taattatata ataatttatg tttgtgccat taaacaatct
     1561 taacagatat ttcattttat ttatgtaaaa caacacgaat aattattgct tcgtaaagtt
     1621 atatgagtat aagttaattt actggaggta gtgcaatgct tttttctgaa agatttggtt
     1681 ttaaaaaatg gaggatatca tactgagaga tagattgaca gaccctctta aaaatagttt
     1741 agcaaatgtg atttatgata tattacgaga ggctgataaa gtttatagta attataatgg
     1801 aaaagtctca tgggtaatat attctttttt aattaaagag ttttttaaag aacagataaa
     1861 taatagctat gagttgggtt atcattttac tgtttattat gaagatatta tcaagaggtt
     1921 agaagacttg gagtggtatg cttattatga tttattagag gtttttgcaa gtgctaaaat
     1981 cttggataaa aagaaaagag aggaagtaaa taaaattctg gagtcggaaa attctggtta
     2041 cagattaagc gaaagcaatg aatttattcc aatcacagat gatatttcta ttaagtctat
     2101 aaatgctgta tctgaatcac catttaatta cgcaaaaaat catatccata aatctcttac
     2161 atatataagc gagaaggaaa atcaagatta taatactgta gtgagagaag caattagtgc
     2221 tgtcgaaagt tgtcttatcg aattttcagg attaccagct aataaaaaaa tactttggga
     2281 actgctataa aagcaattaa agacaaatcg aataacaatg tcgatcttac atttttaaaa
     2341 ccatttgaga caatgtatgg tttggcgagt aataatggaa tacgacatgc agaaaatgaa
     2401 aaaacaattg tctcagattt acctgatgca gttttggtgt taacaacatg ttcagccgta
     2461 attaattatt tgggagtaaa aatagcatat gactccaata aatcatgaaa agttaaaatt
     2521 catccaagag ctacattata actattaatt tccaactctt taaaagttta gtaattgaag
     2581 gaagtaataa gggtgattga acaatacgga tatacggtgt atacttatcg taggagttga
     2641 tgatatgaat attaaaaaac gcaaaatcag agaagtaggt aattcaatag ttgtaacttt
     2701 gtcaaaagag agtttattgc aaaaaggttt gaaacctgga gatactattt ttattgatga
     2761 agataaaatg atggaagcta ttgtaaaaga ggaaagcaag atagatcttg aaattgatat
     2821 gtatgttaac caagctttat ctgagtatga tgcagctttc aaggaattag ttgaaaaatg
     2881 atctatctaa gtgaaaaaga tattgtaaaa ttgaatgtta ttcaaataaa gaaatattca
     2941 ccgcgagaaa caatcggagt cattgacaaa aatgcgctga gtatggctgt aaatcaacct
     3001 aaacagcata tttttggaaa agatctgtat cctgataaat ttagcaaagc agctgttctg
     3061 ctaataaatc tgatcaaaaa gcatccattt cataatgcta acaaacgtac agcattttta
     3121 gccgcgtatg tttttctcaa gctaaatggc tattcactaa aaatgaaaaa tcaggaagta
     3181 gtagaatttg tagttgaaat tgctacgtat cagggtgatt ttgatgactt aaaagaggca
     3241 acaacagata tactaaaaaa gaattcaaca aagaccgatt caaaaaagta gaagcaaact
     3301 agggattcag ttaaatctga agatttagtt tgttctttat tttagtttac ataagataca
     3361 ttatgcgaag ttcattattt taaaagctta aataataaac ttttttataa taccaattta
     3421 tttatgtaaa ccaatgacct taatcgctta agcaagcatg ttatgtaata ctctactctc
     3481 tccaaaacta atgactatct attttcaaag aagctagaat gattatctga tcaaatgata
     3541 atttatattt aattcctggt ctactgctct tcttttaatc aattaatgtc taacgtactg
     3601 tacacgataa agtaggaaga cttattttca acttcggatt cattttttta attcggtgaa
     3661 aatcactaaa ttaagagttt atccaagttc attttagctg agaatacgct tgaaaataat
     3721 tttgatgaat tttcctgaat taaaatttat taacttgttg agtgatataa ttgtaatgta
     3781 ttaccaaata gttagcactt agattagtga tggaaaggaa tagtgagaac aagatgactg
     3841 gtagaaatcc caaagtattt atatcatatt catgggagaa taaggaaaat aaagaatggg
     3901 ctagagaact agcagacaaa ttacttgaaa acggtattga tgcatatata gatcagtatg
     3961 atttaagttt aggtgataga ttacctcagt ttatggagca gcaaatatcc gattcagatt
     4021 atgttctaat tatatgtaca ccagagtata aaaaaaaggc aaataatcgt acaagtggtg
     4081 ttgggtatga aggtcatatt atctcagcag aattgctttc tggaaaaaat gaacgtaaat
     4141 ttatcccaat aattaaagaa ggacgtgcaa gcgaagtact tcctactttt cttgctggaa
     4201 agcttggaat tgatttatca gatagccagc attatgatga aaacttagat gatttaatta
     4261 caactatatt tggtgttaag agaaaaccag cattaggtga tatacctagg catattaaag
     4321 gcagtccttt actacctata gaacataatg aaaataaaga tattgaaatc ttaggaatta
     4381 tcactgataa agtaactgta cctaaaatgg atggctcaag gggttctgca ttatataaaa
     4441 ttccatttag attaaataga gtaccaagtc agctttggaa agagttgttt gttagaaatt
     4501 ggaattcacc accacgatat acaacaatgc atagaccagg aattgcttct gttgtagacg
     4561 atgaaatttt acttaatgga acaactattg aggaagtccg ggaatatcat cgggaaactt
     4621 taaaactttg cattgaaaaa agtaatactc aagaaaaaaa aatattgcta gaggaggaac
     4681 aaaaaaaaga gagagagaat gagcgagtca gatcacataa agaaagtgtt cagaaattag
     4741 cagatgaatt agagttctag ttgatagtca gttctttctt aattcgatac acagtttgtc
     4801 tagttacatt atagtctgtt gctatttttg aaatagcaac accattctcc tggtcctgaa
     4861 cgatgcttct ataaacaagg cgacgttgag gatcttttgt gttcgcactg tataacttag
     4921 gacgtccttt atagacgccg tttgctttag caatctttat cccttgtgcc tggcgtcgtt
     4981 ttgattcagt acgctcttgt tcagcaatca tggccaagat ttgaatgatt aggtctttga
     5041 taaatttatc caggagagga tttccgattg cttcagccat gatcggtaaa ttagtgataa
     5101 taagtcgcac atttttcttc tttagataat ttactgaatc gataatctcg tcataattac
     5161 gtccaagtcg atcgatagcc tctacaataa aaatatcttg gtctctaaca aaatctagaa
     5221 cttcctgaaa aatcggtcga tgagtaatag tcgctccaga ttgtttctcg atgaaaattt
     5281 tttcagcacc aaattttctc atttcctcga tttgacgttg ttcattttga tcgatcgat
//
LOCUS       DAFENC010000095         5311 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.101, whole genome shotgun sequence.
ACCESSION   DAFENC010000095
VERSION     DAFENC010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5311
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.101"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(73..1221)
                     /gene="nagA"
                     /locus_tag="LP493_002777"
     CDS             complement(73..1221)
                     /gene="nagA"
                     /locus_tag="LP493_002777"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBL2134874.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1297..2133)
                     /locus_tag="LP493_002778"
     CDS             complement(1297..2133)
                     /locus_tag="LP493_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2134875.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2317..3534)
                     /locus_tag="LP493_002779"
     CDS             complement(2317..3534)
                     /locus_tag="LP493_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBL2134876.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(3683..3862)
                     /locus_tag="LP493_002780"
     CDS             complement(3683..3862)
                     /locus_tag="LP493_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134877.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            3917..4000
                     /locus_tag="LP493_002781"
     tRNA            3917..4000
                     /locus_tag="LP493_002781"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3951..3953,aa:Leu,seq:gag)
     gene            complement(4240..4818)
                     /locus_tag="LP493_002782"
     CDS             complement(4240..4818)
                     /locus_tag="LP493_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134878.1"
                     /translation="MNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNT
                     MGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGI
                     YLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKE
                     LMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
     gene            complement(4824..5207)
                     /locus_tag="LP493_002783"
                     /pseudo
     CDS             complement(4824..5207)
                     /locus_tag="LP493_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347134.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1653 a         1082 c          838 g         1738 t
ORIGIN      
        1 ttttactaga acacaaaaaa aaccttaaaa ccaaacttaa gaagtttagt tttaaggtta
       61 acttaaatta tattatgcgt ggaaacgttc cacgccatct agataagttg cttccaatgt
      121 catatcaggg ttcaatacga taaagtctgc atcgcgtcct tgagcgattt ttccacatgt
      181 atcatcgatt ttacagctga ttgctggaat cagactagcc atcatgactg cttgttctgg
      241 tgttgctaat ccccagtcta caacattttt aattgcttct ttcaatttca atatacttcc
      301 agctaagttg ccagattcta gacgtgctgt tccttctttt actactactg gaaattcgcc
      361 taaattgtaa tttccatcag gcatcccacc ggccatcata cagtctgtaa ttaatgcgac
      421 atgatcatgt cctgcttttt ccattaggat tcccgcagca tttggatgta catgatggcc
      481 atcacaaatc aattcagaaa agacatgttc taaagataat aacgcaccca ccatacctgg
      541 ttcgcgatga ttcaatccac gcataccatt gaaagcatgg acaaatacac ttgcgcctgc
      601 ttcaacagct ttttgcgctt cttctagtgt agcattactg tgtcctagag aaacaactac
      661 tccttcttca gtcacttgtt tgacaaactc ttctacacct tgacgttccg gtgctaaagc
      721 aatttttttg attaaaccac ctgaagcttc ttgccattca tggaaagtat ccaaatcagg
      781 atccccgaaa taacttgggt tttgtgcccc tttgtgttct tctgtgaaga aaggaccttc
      841 aaaatagatt cctttgattt tagctcctgg tgcttcctga tacattttgc cgattgtctc
      901 agctacatct tttaaacgtt ctttgcttga cgtcaatgtt gttggtaaaa atgaagtcac
      961 tccacaagat aacagacctt cagacatcac tttgatgcct tctgcatcat tatccattac
     1021 atcatgattc atatagccgt gaatatgtgt atctaccaaa ccaggagcaa tccatttgcc
     1081 gctttggtca atgatgttga cttctccctc aggtagttct ttggtgtatt caccaaaaag
     1141 tccatcggta atttcaagat agcctgcatg tttgacacct gacgctaaaa agaatttgtc
     1201 agcatagata aaagttctca ttctattctc tccctttgtt tttctacctc taaagtactc
     1261 ttatttagag aagaagtcaa gaatggtcta caccatttac aaattttttg aaatttgttt
     1321 cacagcttgt gctaagcctt catagaatgc tgctctttct ggttcttctt tacgcttgta
     1381 tattaagctt ttaagcacaa ataaatcatt gaggtaatag tagctattct tctcttgagc
     1441 ccaatagatt ccttgattca cctgttctaa cgcttcgtcg atttcatttt gatggaataa
     1501 gaaatttcca taattataaa aaatttgcga aaattcactt tttgatcgtt catcagctga
     1561 ttgatgcagc agttggatgc ttcgactcaa atagtagcgt gcttcagccg tttttcctgc
     1621 cacaccatat atttttccga tacaactaat cagttgtatt tctgtgtcag aaacatggat
     1681 tctttctttt tggctagagt agcttaatgc ttctttcaaa taataaaggg actgagagat
     1741 attttgacgc aacgtgaatt cgcaaacacc gagataataa taatagcgtt gaaagtcagt
     1801 tgcttgatac agattttcag aaatatcaga agattttagt acttgttcta acttccgata
     1861 atcacgtttt tggaaacaac tatccaacag ttcaaataat ttatcgtttg tccgagtagt
     1921 ttttcgagag agattcatca catgatcaat cgttacccct agccgttgac aaatctgcat
     1981 catcaccaat acattcggca gttcctcatt attttcgatc cgacttaata cactttgtga
     2041 acaaatatca tgcgaaagca ttttttgcgt cattttttgt tcttttcgaa tctctttaat
     2101 gatcgttcca aaggactcga ttaacgtttc cataagtatc ctccccaaaa tatgcgtatt
     2161 cgcattctat tcgtatttta ctttaggaag tcgcaaactt caagaaaaga cttgcaacta
     2221 aataatatac tttagttatt taagaaaact ccactagaaa gagagcctca gtgtgtttgt
     2281 ctgtggccct cctactgaaa aatttggttt ttaaaatcat ttttggcgat aggttgctag
     2341 gaattctctc attttcttag ctgtttgttt caaatcatcc attttaggaa gataaacgat
     2401 tcgaaaatga tctggctggt tccaattaaa tccaccacca tgtacaagta gaatatgatg
     2461 ttcatgtaaa aagtccaaaa cgaatttttc atcatccaaa atattgaatc gctttgtatc
     2521 aatttttggg aatatataaa aagcagcttt tggttttacg gctgaaagac caggaatatc
     2581 attgattgca ttatagatat attctctttg ttcatagatc cttccgcctg gcaggagcag
     2641 ctcatcgaca ctttgataac cgcctagcgc ggtttggata atttgctgag acaatacatt
     2701 ggaacacaaa cgcatggagg acaacatatt cagcccttct atatagcctt tgacgtgtga
     2761 cttatctcca cttaggacca tccagcctac tcgaaatcct gctacacgat gagatttgga
     2821 tagaccgttc agcgtaacaa cgaacaaatc aggcgctaat gtagcaatcg gaatatgttc
     2881 tagaccatcc atcactaagc gatcatagat ttcgtcggaa taaataatca ggttattttg
     2941 tcgagctact tcaacgattt cttctaataa ttcttttgga taaagtgccc cagtaggatt
     3001 attaggatta atgataacaa tagcttttgt ccgactcgtt atttttgatt tgatatcatc
     3061 aatatcagga taccattctg cctcttcatc gcaaatataa tgaacaggtg tgcctccagc
     3121 taatgcaata gaagccgtcc acaacggata gtccggcatt ggaaccagta cttcatctcc
     3181 attgtccagc aacccctgca tacacatcgt gatcaattcg ctcactccgt tgccggtgta
     3241 gatatcattg atcgtcacat tcggaaaatg tttcagttgg caatattgct caattgcttt
     3301 tctagcagaa aagatcccct tggaatctga gtagccttct gagtcacggg cattcatgat
     3361 caaatcacga atgacttcgt ttggtgcttc aaatccaaaa ggtgcgggat ttcccgtgtt
     3421 caattttaaa atactaatgc cctcttcttg catccgctcc gcttcttcta gaacgggacc
     3481 gcgaacatcg taactgacac cttctaattt gttggatttt tcaaattctc tcatcactta
     3541 gccaatccct catttcaaaa agttagaact ttccaaattt tttgttattt actatttcaa
     3601 tatcatactc catcctagaa aattttgcca cttatttagg aaaaacgtaa gtattaaaaa
     3661 aacacaaaca agcgttgaga acttaattgt catgatagtc attccataga ttcgctgccc
     3721 aatccattgc aattccacaa atgattccta gcataaaacc aagcaaaaaa cgtccgaatg
     3781 caagtccaat caatacacct aagatcattc ccagtcctga aaattctccg tcatatttct
     3841 ccatcttaat aagtcctccc atttttgagc ttgacaacta tgtaaaacct cgctatcatt
     3901 agtgtgttat tattacgcag atgtgttgga attggcagac aagcatgatt gagggtcatg
     3961 tgagcgttag ctcgtgtggg ttcgagtccc atcatctgca ctacaactcg tgaagttaat
     4021 tttgcttcac gagttttttt gtttgaacgt ttctttatgc cattatatac atatcactgt
     4081 atcctttaca aaaagaacgt acaatcatgt aaacagcctg aggtgagtat atgaaggtcg
     4141 gaaacaagct actcgtagaa acttgcaagt gttaaaacaa ttaatcgaaa aacgagtaaa
     4201 atccctcacc taatactaaa gcgagggatt ttttgtatat tatctgttta tcaccgttat
     4261 tataaaggta caaataccaa gcacggttaa tccaaattgc ataaattcat ttttttgtac
     4321 actcatgctt ttcattagct ctttaactgc cattagtact aagatggcga taacaacata
     4381 aagtatatag tacgtccgca ttccggaagc ccatactgtg ggagaaaatc ccataattaa
     4441 ccttgaacaa aatcccatta tcatcaaaat aactaaaaaa atagaagttt tcttattgtc
     4501 aaaacttaaa taaattccaa caattaaaca tagtaataat gccaagacta ctaaagtagc
     4561 tatccaagta cctggataaa aaagtgacag tttcgttcct aactctgtaa agagattatt
     4621 caggttacta ctactccaaa tcattgccct tttatttcca ttgacgtaag taaagctttg
     4681 acccattgta ttaccaaaat aaataatcag gtttaagaaa aacggtaatg cagtcaatat
     4741 acgcacataa tagttttgac atttcctata tgttagaagg aaaattaaga aaaatagcaa
     4801 taaaaataag atattcatgt ctaaaaaaac ggctttccaa atgatgaaat acctaaatct
     4861 aacttattaa gaaagttgaa atttttatat tcaggaaacc atttattaat ttcatgtgca
     4921 gcacgtaatg cattccctgg agttgtcaaa gagaaaatta attctgctaa gcttattatt
     4981 gaaaatactg ataacttata attatatcgt ccattgacaa tcaaatataa actaactata
     5041 cttgttagaa caaaaaaaca ggcgttgact tgttcttgat tagttaaaaa tatcaataaa
     5101 ggaatactta cccaatatat ttttctattt atttcttctc ctcttaagag ttgaaaaaac
     5161 ggataaaaag ttagtaaact aaatgctact ggccactgat agttcaaggt ggttgctctc
     5221 caaccggttt cccccattac tgtcaatggt attaaacagt atatagagca aaccaataat
     5281 aaatttttaa catttatttt ctcaaaaaca t
//
LOCUS       DAFENC010000096         5206 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.102, whole genome shotgun sequence.
ACCESSION   DAFENC010000096
VERSION     DAFENC010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5206
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.102"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            33..1367
                     /locus_tag="LP493_002784"
     CDS             33..1367
                     /locus_tag="LP493_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134879.1"
                     /translation="MDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVLYYAY
                     GLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIKFVVV
                     NLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNNDITT
                     YTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLLQF
                     PWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAKVIQS
                     KHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKYKAAD
                     NNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIEIT
                     TKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
     gene            1354..2988
                     /locus_tag="LP493_002785"
     CDS             1354..2988
                     /locus_tag="LP493_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134880.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            3163..3996
                     /gene="msrA"
                     /locus_tag="LP493_002786"
     CDS             3163..3996
                     /gene="msrA"
                     /locus_tag="LP493_002786"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBL2134881.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQGERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            4109..5065
                     /locus_tag="LP493_002787"
     CDS             4109..5065
                     /locus_tag="LP493_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBL2134882.1"
                     /translation="MEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQREILRGAFDMG
                     ITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMWEGPYGEWGSRK
                     SIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGKALYIGISNYNG
                     EDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGAITFSPLAQGLL
                     TNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQSLAQMALAWNLR
                     QKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
BASE COUNT         1824 a          806 c          951 g         1625 t
ORIGIN      
        1 gtttttatta tggagaaaag ttttttaaaa agatagatgc tgctttttta tttagttgtt
       61 tatatacttt tgcaacttat cgaacagttg atatctatta tcgatccgca attgcagaag
      121 caatcgctct tacgattatc ccagctgttt tatattatgc ttatggattg atattcaata
      181 gagaaaaaaa agtcatcgct ttatctgtca gtataagtct acttgtgtat actcatgtct
      241 taactacact attgtgtagt gcattgattg cttgtatgat tatagttcgt ttgtttttaa
      301 gcaagcaaat aaaaaacgat ataaaatttg tggtcgtgaa tttagtaaag gctgtttttt
      361 tgacttgtgc attaactagc tatttttggt atcctatgtt gcagcagatg aattatcaag
      421 aaatacacag tcccttcaaa acagatttgc agctagaagc actttctatt tcagatagta
      481 tcattcaagc gttaaataac gatattacaa catacactat ggggttatta ggattggttg
      541 cgttgatttt tcctttattc atactgaaag aaatggagaa aaaagaaaaa atcatctatg
      601 ttggcgtagt ttctacatgg gtatgcgtaa ctaatttatt tccatggttt ttgtttcaaa
      661 aaacaccgat aagcttgctc cagtttcctt ggcgtatctt aggtatccaa atcttttttt
      721 cttcaatgat cataacgctt gtttttatga aaaagactat gaataaaaaa tattcatggt
      781 taatcattgg cgctactgtg gtgtttctac tcgtcacgtc tatagcagca aaagaaaatt
      841 acgcaaaagt tatccaatca aaacacggtc atattgttat caatgaagaa acactcccac
      901 gttatacaac atcagatatg ggaggattat acgattacgc cccaacagaa gcgataaaag
      961 aaaggcctca cttagaaaaa catgaagtaa aagtaggaga atcgtgggaa aaagggaagt
     1021 ataaagctgc agataataac attacttaca cagtggcaag caacaaaaag caaaaagtga
     1081 cagtaccagt atatgcttat ttaggtacac aggtaaaagt aaacggtaaa gtcgtaaatg
     1141 actcttataa aaaacatggc ttagtgaatg tggatgtaaa tgctggagaa aataagatag
     1201 aaattacaac aaaatatact ccaactgctc tcatggcttt atggatcagt attctgactt
     1261 attgtttagt ggtgtattca agttttaaac gatttgcacc taataagttg aaagattctc
     1321 gatatgtgac taaaaaggag ataaacaaga agaatgaaaa taaataaaaa agtagtaata
     1381 ttgagtggat taattatagt tagtagtata tattctttca tctttttcaa aaatacacag
     1441 agtatttata ccactggaga tctttctttt cacttatctc gaatcaaggg gttatcgact
     1501 atttttacca gtccgattaa ttatgagaca ttcaattata ctggatatgg tgtaaattat
     1561 ttttatccct ttctgacttt ttttccagct gtaatgttat attggatgac aaaaaatttg
     1621 attgtaagct atattattta cgtttggtta ttgaacttgt gtacaacact cgtagcttat
     1681 cattatggcg agcggttttt aaaacaaaaa aaagcggcat ttttatttag ttgtctctat
     1741 attttctctg cttatcggac agtagacatc tactatcgtt ccgcaattgc cgaagctatc
     1801 gcaataacac ttgttatccc tgtattattt tatgcttatc aaatcatctc tggaaaagaa
     1861 gaaaagtatc cgtctgtaaa gctagcattg agtatgagtt tgctagtgta cagccatgta
     1921 ctatcaacat taatgagtac agcattaatt atcattttta tttttattcg tttggtttct
     1981 aaaggtttca agaatgcaga ttttattgct atatttaaaa aattatttag tgcggcagga
     2041 atgacattgg ttctgacgag tgctttttgg tatccgatgt ttgaacaaat gctctaccaa
     2101 aaaatcaaca aacctagcgt gacaaattta tatgctcatg catctaatgt gttcgatagt
     2161 ctgactgaag ctatgaacaa cgacttaact acttactcaa tgggactagt tggtctgtta
     2221 tctttatgta ttcccctgat tttatttaaa aaattaacaa acatagaaaa aaagatttat
     2281 tatggtacgt gtttgacttg gctagctaca actagtttgg tgccatggta tcttctgcaa
     2341 aatacgccag ccaaattgtt acaatttcct tggcggatct taagcttgca aataatattc
     2401 tcttctctga tattaacgat gatatttttc aaaaatagaa gatacaataa gacaagagaa
     2461 ctattttatt tatttatgac tgttttgtta ttaatcactt taactgtttc tagtaaaaaa
     2521 aatttcaatc aaaaaataat ttctcagccg ggacatattg ttgtaaacaa agaaacagta
     2581 gaggcgtata ccactaaagg aatggattat tttttatatg attattctcc tatcgcttca
     2641 ttggagaata aggagcatat aataaaacac gaagcaaaga ttggcagtca atgggtaaac
     2701 cttccttata aaacaactgg tagttctatc atatatagag taactaatga gaagagccaa
     2761 gtaatcacac ttcctgtata tgcttattta ggaacgaatg tagaaataaa tcatcaacct
     2821 gtaaaggagc aggtgaatgc taatggattg gtacaaataa gcggagtcaa aggagttgct
     2881 gatattaaag taagcacaag ttatacagta acgactatta tttcttatct tgttacatta
     2941 actgcatatt tatgtttatt ttttaaaata gttttccata aaaggtaaat taacttttca
     3001 tttataaaat aaattgatta aaaaggagaa tctgtcgata aggattctct cttttttata
     3061 cgaaaaatct gtagggggat gaagtaatcg cttatttcct cactttatga taaattacag
     3121 ctaaagtcac tagcttgtct tcttcggaaa ggaggagaat ctatggatga ggaacaaata
     3181 ttcattcaaa cactttataa tctgattttg aatccgaata cacgagattg ggaacgaaaa
     3241 gtattgattc agacaaagaa tgacataaga gaaaatatat ccgttaaaga acagttatca
     3301 aaactagaag caacactacg tccattagct atccgaatga atctgacgcc tgatgtaatg
     3361 gacttttatt tattgattac ggaaggattt gataaggagc aaaaatatga cttttccaag
     3421 catgccatgc aagatgctga ctatcaagaa cgtgcagtat ttgcaggggg atgtttctgg
     3481 tgtatggtcg agccgtttga atcgaaaaaa gggatcctat ctgttttgtc aggatacacg
     3541 ggcggacatg ttgaaaaacc aaattatgat caagtaagtg gtggttacac aggtcatgtg
     3601 gaagctgtgg agatcattta tgacacaaga gaaataagtt atagcgagtt gctgacaatc
     3661 tattggcaaa ttactgatcc cacagataca tttggacaat ttcaagatag agggaagcaa
     3721 tatcgtccag tgatttttta tcaaggcgaa cgacaaaaag aattagcgga acaatcaaaa
     3781 cagaaactag acagttcagg aactttccac caaccaatcg tcacaaaaat cgaaccagcc
     3841 ggtacgtttt ggccagcaga aaactatcat cagcaatttt acaaaaaaca accgaaacgt
     3901 tataaaaaaa tccagcaagc acgtaatcaa tttctgatct atcaacgagt aaaaaacaaa
     3961 tggcaaaaaa atatacgaaa aaatcatttt gattaactcc ttttctttaa aatgtagtaa
     4021 actaaaaata gaaaaaagaa agcgttttaa aaagatttga tgaggaggag aaaaattgta
     4081 tattgcagat agtgcacgtt atgaaaaaat ggaatatcgt aaatccggtc attcaggttt
     4141 gaaattaccg attttatctc tcggattatg gcaaaatttt ggtgattatg atcctatcca
     4201 taatcaaaga gagattttaa gaggcgcatt cgacatggga attacccatt tcgaccttgc
     4261 gaataattat ggaggccctg ctggagctgc agagaaaaac tttgggcgta tttttagaga
     4321 agattttcaa gcctaccgtg atgaactgat tatttctagc aaagcaggtt atcatatgtg
     4381 ggaagggcca tatggggaat ggggctctcg taaatccatc atttcaagtt gtgaccaaag
     4441 tctccaaaga atggggctag attatgttga catcttctat catcatcgcc cagaccctga
     4501 tacacctttg gaagaaacag cagaagcttt gatgcaactt gtaagacaag gaaaagcatt
     4561 atatattggt atatccaact ataatggaga agatacaaaa aaaatgactg aaattttaaa
     4621 aagaaaggaa gcaccgttca ttattcatca gatgcgctac aatatgtttt ctcgtgcact
     4681 actagaagac gatctatctc cagtattaga agaagaaggg ctaggggcaa tcacgttcag
     4741 tccgcttgct caagggttgc tgacaaatcg ttatctacat ggtattcctg aagattctag
     4801 agcacatcgt aaggaaatac cattcctttc agaagaacaa gttggatcaa ctctggaaaa
     4861 aatcaaagca ctgcaaacaa tcgccgtatc acgaggacaa tcattagcgc aaatggccct
     4921 tgcatggaat ttgcgacaaa aatctgttac aagtgtactg gtcggagcaa gtcggttaag
     4981 tcagttacaa gaaagtgttc gaatgatgga taatttagat ttctcaccag aagaagaatt
     5041 gagaatcgac caaattctag aatagaaacg atgtaatcaa actttttatc catatattaa
     5101 aaaaaacaaa agatgacatc aagaatcgaa tgaagatcgt ctgttattga acatcatatt
     5161 ttttgtcgtt caaaataaaa atgatcgaag gctaggagtg aatttt
//
LOCUS       DAFENC010000097         5025 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.103, whole genome shotgun sequence.
ACCESSION   DAFENC010000097
VERSION     DAFENC010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5025
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.103"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            283..522
                     /locus_tag="LP493_002788"
     CDS             283..522
                     /locus_tag="LP493_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134883.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(884..1144)
                     /locus_tag="LP493_002789"
     CDS             complement(884..1144)
                     /locus_tag="LP493_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134884.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(1329..1826)
                     /locus_tag="LP493_002790"
     CDS             complement(1329..1826)
                     /locus_tag="LP493_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HBL2134885.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            complement(1956..2666)
                     /gene="budA"
                     /locus_tag="LP493_002791"
     CDS             complement(1956..2666)
                     /gene="budA"
                     /locus_tag="LP493_002791"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HBL2134886.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(2679..4343)
                     /gene="alsS"
                     /locus_tag="LP493_002792"
     CDS             complement(2679..4343)
                     /gene="alsS"
                     /locus_tag="LP493_002792"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HBL2134887.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(4548..5015)
                     /locus_tag="LP493_002793"
     CDS             complement(4548..5015)
                     /locus_tag="LP493_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134888.1"
                     /translation="MIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLFAWIVSVI
                     MIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVLRIAFYYT
                     LKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTMDL"
BASE COUNT         1529 a         1043 c          771 g         1682 t
ORIGIN      
        1 ctatcctcct agcaactatt taaataccca aaaaaattac ctctagataa tatcatacct
       61 acgttttcac ttataaattt tttcataaaa aaagcgttta gaggcataat cgttaataca
      121 gatggtaacc aatgtatctg gtttgaactg ggatatcacc ctctccatat atgtattact
      181 aagactaata gatactataa aagacttgat agttttgcat tgattttgcc taatactgag
      241 cataggtgta tgctaaacga tactataagg agtgtgtaca taatgaaaag aattctgttt
      301 atcagtttat caaatttatt gttacttact gcttgtggga cttctgcatc aaagaacata
      361 ccttcagata cgcaaatttc gaatagtatc gattcaacaa tttctacaaa tgagaaaaat
      421 tctccggtag aaacttccga tataaaagtt tctacctctg caaaaaacag ggtaaagaaa
      481 ctgtcagcac gtctccttta tttcaaacaa actctgaatt agcttcttca tcttcttcag
      541 caaataatga tgatagtttc gcgtttactc ctaactaaat gcaaccttta caaatgcttt
      601 acgataacaa gcctgagcta aatgatcctg atatcagttt tgcatttttt gaaatgattg
      661 gatcggatga tctttttaaa actactagtt tgtctatccg aaaataggac agttctggca
      721 gtataggttt ttatcgagtt tctccaccag gcctcgttac agagacagat tctctaggcg
      781 aaccttttga ataaatcaaa aatcatgaac aatcactgcc aactaaataa agtgccttca
      841 aaagcttggt cttctcgctt ttgaaggcac tttatttaaa tctttatgaa actaaagtat
      901 gttcatattt gttgctatag ttatatagat attctgttgt ttccaactca taaacgtgag
      961 tatattttgc cactactttt ccgcattttt ctaatatttc attgcgatcg acgtcatgat
     1021 attcgtctac gcagatcaca acacaatttt ctaatttact gattacttct ccaaccactt
     1081 tttgtttcaa gccaataggt tggcaaatat atttttttcc taaaatgata gtttcgttat
     1141 tcatatttca tccatcctta atgtttttcc attatttaaa atgataatac cattaaaata
     1201 tgattatgaa aatcaataac acttgtgatt ttataaaaaa ataaaaaaac cgaaaaacag
     1261 aaatgcccac tgtctttccg gctcttttta ttcttgattt ctcttctttt ttgtttcaat
     1321 agacgatttt agttattaat aaatgaaaaa gcatttatat taaaatttgc taataaaaga
     1381 tctacatatt tttctagaaa tgcttgatcg atttcatcat accctttcgt tactccgcaa
     1441 tcgatatcta aaacaccgat taaattacct tcttttacca ttggcactac gatttctgat
     1501 tgtgcggctg aatcgcagga aatgtaattt gcatgggttt tgacatcatc aacgatcaat
     1561 gtttcttgtt tttcagctga ttctccacaa actccttttc ccatcttgat acgtgtgcaa
     1621 gaaactcgcc cttggaacgg tcctaaaatc aattcattac catcgaataa ataatatcct
     1681 gcaaagacag tctcaggcaa agtctcattc aacaatgcag atgaatttgc taaatttgct
     1741 aaccagttat cttctgcttc taataatcct tgttgctgta ataataaaat ttcgtatgca
     1801 tcttttttct gtttttctgt ccacatgata aaaaccgctc ctttttgatc tatggagaag
     1861 attatagctc agtttttttg taaacgctag gtttcctcct caaaaaaacg agatacgtca
     1921 ggttaatcac cttgaacgca tctcgctgtc tttttctatt ctgcttgttg gatttctgct
     1981 gctaaatcag cataatcaat cgtttcgtga acaaaagtcg gatcatcaac tggaaaatgc
     2041 tgtacaaggg acgagatgcg gctaatctca acttttcctt cagccacttc aaaatccatt
     2101 acatgtccgc caaatgtatg tgtatcatcg ataaaatgca agtgaaatcc cgctgcagca
     2161 actccttgga ataattcagg cgtaaagaac ccgactaatg ttccttggac attgctttgt
     2221 tggaattctg gttgagactc tgaaattttt gctagtcttc tgtaaggttt ttcttgcttc
     2281 ggcatgatac ggatgtgcat atttttgaat aatccagtta tcttcactgc caaaaatagg
     2341 ttttccccgg cttctcttac taatatgtct tttttcaatt gttctccatc tgcagttttt
     2401 gagacagaaa aactagtatc tggcgtaaaa tctgtaattg ctgcataggg ggtaagttca
     2461 cttccatcta attgggcaac tgagccatct gatcttcctt gataagctac gccatctaaa
     2521 aagatgactt caccatcaag cccatgcaat gttcccaatc ccagagttcc tttttctaat
     2581 atatgagcaa tcgtttctgt tccatccatc aagccagcca tcaaagctcc taatgtcccg
     2641 tgctggtata agattttttc agtcatgtcg acacttcctt aatagaattg atctggtaag
     2701 attgtttctc ccaatttctc attatcacgg taatcaatcg gaatatcaat aattacgggt
     2761 ccttctgtcg caaatccttc ttctaaagct ttttctaatt cctctacact tgtagctcgg
     2821 attcctttag cgccaaaagc ttctgcatat ttcacaaaat caactggacc aaagtctaca
     2881 cctgacgccc gctgatattt cattttttct tggaactcta ccatattgta gtgtccatca
     2941 ttccaaatca aatgaacgat attcaatttt ttacgtaccg ccgtttctaa atcctgggca
     3001 gagaataaaa atcccccatc gccggaaact gatacgattt gtgtatttgg acgcaccaat
     3061 gcagcagaaa tcgcccatgg caatgcaaca ccaagcgttt gcataccatt actgaataac
     3121 aaatgacgag gttcataact tctaaagtgg cgtgccatcc aaatataatg actacctaca
     3181 tctacggtaa cagtcatatc atctgttact tttgactgaa gcgtgttaat aacttctaaa
     3241 ggatgcaaga tacctgcttc tccttttgat tgaacaatgt cccgctccgt taattctgct
     3301 tgaagagatg ctaaatattc ttttgcatct tctgacactt gttgaggctc taatgaacct
     3361 gtcaataaat caagagtggc tgagatatca ccgatcaatt ctctttcagg ctgcataaaa
     3421 ggatcgattt cagctggcgc ttcatcgatc acaatgatcc gcgcatcttt ttccgcattc
     3481 cagtttcttg cttcatattc gattggatca tagccaatag caataactag atcacttcgt
     3541 ttcaaaagca tatctcctgg ttggtttcta aataaaccca cacgaccaaa gaaatgcgct
     3601 tctaattcac gtgagatcac tccagctgct tggaatgtct ctacaacagg caatgctgtc
     3661 tttccaacta attgcctgat ggctaacgtt tctttttcac ttgatcctcg catacctact
     3721 aatagtaccg gtagttttgc ttctctaatg cgttcagcta ggtaacggat atcatctgca
     3781 gaagcagaac ctaatttagg atcgctcaat ggcttgatga cattcccttg gacaggtgca
     3841 tccactacat cttgcgggat actgataaag ctcgcgcctt tttttgaact cttagccata
     3901 cgataagcat tggcaatcac ttctgaaatt gtttctggat cttggatttc tgcactgtat
     3961 tttgtgattg gctggaacag tgctgcatta tccatgcttt gatgggtcaa cttcaataga
     4021 tcgcttcgtt ttacttgtcc ggcaattgct aaaactgggt caccttctgc tgtcgctgtt
     4081 accaaacctg tagctaagtt actagcacca ggaccacttg ttgcgataac tactcctggc
     4141 tctcctgtaa tacgtccgat tgcttgtgcc ataaatgcag cattttgttc gtgacgagtc
     4201 acgattaatt caggaccttg atcctctaat tcattaaata caccatcgat ttttgcacct
     4261 ggtataccga atacataatc aacatgatga ttaatcaaac tttctactac agatttcgaa
     4321 ccttgtttca ttttttcgtc cattgaacat cgtccttttt atgctttatt tttaattatt
     4381 agttagaaat aatcacaaat aattgataca gtttctaaac ctgtttcatt caaaagtata
     4441 gcacgtttta tttcatttgt ttagccatat gtttcaaaaa atgaaaaaga atgacagttt
     4501 ttacataaaa actgtcattc ttaattgaaa gtttcaattt ataaagtcta cagatccata
     4561 gttctcatca atttacgatt gttgaagtaa atcaaaccaa atacgataga aggacctagt
     4621 agaatacacc attggggctt tacgaaaaag aagagaaaca aacttgtcaa tagtaaaaaa
     4681 tctagtaaac tcacatacca ttttttcaac gtatagtaga acgctatccg tagaacttga
     4741 tttggtttcg acgctggatt tctcacctga aaataccagt agttgatgct aaaggaaact
     4801 gataaacaag caagtaaaac aaacaacgga atcaaccatt ttccataaga aaaacgtata
     4861 aaaaagaaac aatcaaaaat cattatcaca ctaactatcc aagcaaatag ccaataaaaa
     4921 aatcccttta gccaaaattg gcgaaacgtc tttatgaaca aacgtactgg tgaaaaactt
     4981 ttttcttttg ctaattcttc tgtcatacct atcatcacga tgcaa
//
LOCUS       DAFENC010000098         4926 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.104, whole genome shotgun sequence.
ACCESSION   DAFENC010000098
VERSION     DAFENC010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4926
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.104"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            85..972
                     /locus_tag="LP493_002794"
     CDS             85..972
                     /locus_tag="LP493_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBL2134889.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1112..2038
                     /gene="cysK"
                     /locus_tag="LP493_002795"
     CDS             1112..2038
                     /gene="cysK"
                     /locus_tag="LP493_002795"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HBL2134890.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2274..2720
                     /locus_tag="LP493_002796"
     CDS             2274..2720
                     /locus_tag="LP493_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBL2134891.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2993..4345
                     /locus_tag="LP493_002797"
     CDS             2993..4345
                     /locus_tag="LP493_002797"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HBL2134892.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4516..4803
                     /locus_tag="LP493_002798"
     CDS             4516..4803
                     /locus_tag="LP493_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134893.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1695 a          813 c         1030 g         1388 t
ORIGIN      
        1 aattaaaagt ataatttaat taattaagtt tgttttaaga agagaacttt ttattaagtt
       61 tttttatttt gaggaggaat ttgaatgcaa gagctgaaga cccgcagtgc ccggcaccat
      121 agacctaaaa gaaaaatggt gatcaataaa aaagcgattg ctcctttaat tggaacgagt
      181 cttttagttg ggccgatgat ggttacagcg gtaccgcaac atgttcatgc agatgaacaa
      241 ggatctcaaa cagtcgctga tcctcaagcg tttatcgatc aaatcggctg gtctgcgtca
      301 gaagttgctg caagtaatga cttgtatgct tcagtcatga tcgctcaagc gttgttggaa
      361 agtgcatatg gcacttccgg attagctagt gcgccaaatt ataatctatt cggtgtgaaa
      421 ggaagctata acggacaggt cgtttatatg gcaaccaaag aatatgtaaa cggacaatgg
      481 gtaacgatga atgagccatt ccgaaaatat tcttcttatt gggaatcctt ccaagaccat
      541 gcgaatgttc ttcgttcaac cagtttttcc acgggcgatt atcattatgc tggcgtgtgg
      601 aaaagcaata caacaagttt ttatgatgca acagcgtact tgacaggtcg ttatgctacc
      661 gatccaaatt atggggccaa attgaactca ttgattaata cttataattt aacccgtttt
      721 gatacgccat caacaggttc ggctacaaca accacaagta caacaacaac gactactacg
      781 acgacttcaa cgtcatcatc ttcaacaaca gatgtaaata caaataatgg tcagacatat
      841 acagtcgtgt caggtgatac gctatgggat attgcacaaa aatttggcat gtctgttgat
      901 gatctaatgg cgaaaaatgg catgtctatg tccagttatt ctttattagt tggtcaagaa
      961 ctaaacgttt gatttagata aaaaggcaaa gaaattacca tatatggtat atctttgtct
     1021 tttttttgct agtcaaagac gaatcactcg ccataaatga acagattgta ttatgataag
     1081 taagaagagc aaagacaagg aggaattgaa gatgacagct atctataact cagtcaccga
     1141 attgattggc aaaacgccaa tcgtcaaatt aaataaaatc gtaccagaag attcagcaga
     1201 tgtttttgta aagcttgagt tttttaatcc aggaggaagt gtaaaagatc gtattgcttt
     1261 aagtatgata gaaaaagcag aacacgatgg tctactgaaa ccaggtgata ctatcattga
     1321 acctacttct ggaaatacag gaatcggatt gtcgatggta ggagttgcaa aaggatataa
     1381 agtaatcatc gtgatgcctg agacgatgag tatcgaaaga cgtttattga tgaaagggta
     1441 cggcgcagag ttgattttga ctcctggtgc ggatggtatt tctggatcaa tcagagaagc
     1501 agaacgtttg gcaaaagaaa acggctactt tttaccatta caatttgaaa atgaagcaaa
     1561 tcctcttgtg catgagaaga cgactggtcc tgagatacat caagcatttg gagtaaatgg
     1621 cttggacgcg tttgttgcag gtatcggtac aggaggaacg atcactggcg ctggccgaga
     1681 attaaaacgt gtgtatccga aaatcgaatt aatcggggta gaaccagcag aatctgctat
     1741 tttagaaggg aaagaagcgg gacctcacaa aatccaagga atcggtacag gttttgttcc
     1801 taaaacactg gatacttctg tgtatgataa agtcctttct attagtggag acgaagcgat
     1861 ggaaacagct agagaagttg ggcgaaaaga agggatttta gtaggcatct catctggcgc
     1921 tgcaattgct gccgcgctaa aagtcgcaaa agaattagga aaaggcaaga aggtattagc
     1981 tgtggttccc gacaatggtg aacgttattt atctacagcc ctttaccaag agatataagg
     2041 cacttggttt ttctccagat aggtttatgt aaaaaacttt taaagatgaa aagaacacac
     2101 aaaaatttat gatgagaaaa attatttgaa tagagacgta gaatagtgaa cgcgactgtt
     2161 ttacgtcttt tttcattaaa atacaataaa attgaatttt cttttcatgt taagtggatt
     2221 ttaaaatgta aaaatagtat gataagacga gaataacaac gtggggtgtt tacatggaaa
     2281 ataagttagt cgaagaggtt atcgaaaagt taaaaaaaga gaacattcga atcacacctc
     2341 aacggtacgc ggttttagaa tatttgattg aacatcattc ccatccaacg gctgatgaga
     2401 tttataaagc acttgaacat cggtttccaa atatgagtgt tgcgactgtt tacaataacc
     2461 ttcgcttatt tacttcgatt ggatttgttc aagaaatgaa gtacggcgat gcttctagcc
     2521 gatttgattt cagttcaaag cgtcattatc atgtaatttg tgaaaactgc ggtaagattg
     2581 ttgattttca ttacccaggg cttgaagata tagaaatggc tgcaagcaga ctgactgatt
     2641 ttgagattaa tgaacatcgg ttggaattgt atggactctg tccggattgt aaagagtcag
     2701 caaaaaaggc gcaaatgtaa aaacagtttc tacaagtgtt atacctaaaa aaagctagct
     2761 gtgtaaaaaa aacgctagct tttttatttt tttgtctttt attcacaatc ttagatataa
     2821 aagtgaatat tattaaaata agaatcttgt agatattggg ttcttatgct tgaaaaggaa
     2881 tgaaactaca aacaaacctt tgtgaattca caagcattaa actgttgtat ccgttttatt
     2941 tctgttatag tagttttgtc gaaggacaaa atgttaatcg gagggaccat aaatgaaagt
     3001 agtagtaatt ggctgtactc atgcaggtac tgcagctgta aaaagtattt taaaaaatca
     3061 tccagaagca gaagtgacag tatatgaaag aaatgacaat atttctttct tatcttgcgg
     3121 tatcgcactt tatgtcggcg gagtagtaaa ggacccagca ggcttgttct actcaaatcc
     3181 tgaagaatta tcttcattag gagcaacagt taaaatggaa cacgatgtaa cagacgtcga
     3241 tacagaaaat aaaacagtaa cggcaaaaga tctgaaaaca ggagaaacag aaacggtttc
     3301 ttatgataaa ttagtgatga caactggttc atggcctatt atcccaccga ttagtggaat
     3361 cgatgcgaaa aatgtactcc tatgcaaaaa ctacaatcaa gcaaatgaaa ttattgcaca
     3421 agcgaaagaa gcaaaacgtg tagtaattgt tggtggtgga tatatcggta ttgaattagt
     3481 agaagctttt gtcgaatctg gaaaacaagt gacattgatt gatggattag atcgcatctt
     3541 gaataaatat ctagataaac cattcacaga tatcttagaa aaagaattga cagaccgcgg
     3601 tgttactctt gcgctaggcg aaaatgttac tgaatttatc acagatgaag aaggaaaagt
     3661 gaaacaagta gctacaccaa cagatacatt tgatacagat atggtcattt tatgtgtggg
     3721 cttccgtcca aatacaaaac tgatcgaagg aaaagtagat acactgccaa acggggcaat
     3781 caaagtgaat gaatacatgc agacaagtaa tccagacatt tttgcagctg gagactctgc
     3841 agtagtcaac tacaatccaa gtggcacgca aaactatatt cctttggcaa caaatgccgt
     3901 tcgtcaaggt ttgcttgtgg gaaataactt gacagatcat aaaatggcgt atcgtggtac
     3961 tcaaggaact tcaggacttt acctatttgg ctggacgatc ggttcgacag gtgtgaccaa
     4021 agaaagcgca actttgaacg atctagaagt ccaagcgact gtatttgaag ataattatcg
     4081 tccagagttc atgccaacta ctgaaaaagt aatgatggag ctagtctatg aaaaaggaac
     4141 gaatcgtatc gtaggtgctc agttcatgtc caaatacgac attacacaat cagcaaatac
     4201 catgtcttta gctgttcaaa ataaaatgac tgtagaagat ctcgcacttt cagatttctt
     4261 cttccaacca cattttgacc gcccatggaa ttacttgaac ctacttgcac aagcagcgct
     4321 aggcgaaatc gaaactgcac aataaagaaa aagggttgtg acacaatttt gtcacgaccc
     4381 tctgtctttt tttgtgaaaa gtacaattag ttgtctttct tcgaattttt tgtcacaata
     4441 agcagcaaag ataaagctgt tacataaaag aacaagcagc tttatttgat tttgaaaaga
     4501 aaggtgagaa agaagatgaa taaagaatat tttgtccaac aagatgcatt tttagaagat
     4561 tataaaagtg cttcgaagaa attaacgatc aatattgatg agttggcaga tcaagtactc
     4621 tctcagttga atgaaacgca agaggaatat tacacgatgc cagcaaatga cgccaaagat
     4681 aatgtttctc atcgttttcc tttcagtaga cgcatctact cagatgaaaa tgacggcaca
     4741 ttgaatacag agtacacata tgaaggtcag ccatatgtgc tagaaactga tgatgatctt
     4801 taaagacagt ttttgaaaag gccgctcatc cttaagtgat gacaaaaaat catcacaatt
     4861 accgatgact gtctctttac tatcttttaa tcagaaaaag gggttatgac aagctttgtc
     4921 aacccc
//
LOCUS       DAFENC010000099         4808 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.105, whole genome shotgun sequence.
ACCESSION   DAFENC010000099
VERSION     DAFENC010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4808
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.105"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(89..1174)
                     /gene="xerS"
                     /locus_tag="LP493_002799"
     CDS             complement(89..1174)
                     /gene="xerS"
                     /locus_tag="LP493_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HBL2134894.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
     gene            complement(3250..3768)
                     /locus_tag="LP493_002800"
     CDS             complement(3250..3768)
                     /locus_tag="LP493_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HBL2134895.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT         1579 a          786 c          730 g         1713 t
ORIGIN      
        1 taaaaatgat aatgaagctt gcctttaaag ttgggctttt atctaatttt agagacaggc
       61 ttcattatta tactattttt tactacattt acaaagcgtt caaagcatca attgtagctg
      121 cattgtctat atgagtatat aaagttgttg tatttgtact tgtatgtccc aattgttggg
      181 cagttaatac caatgaattt gtctgttgat agagtctagt agccaaagta tgacgtaatt
      241 tatgtggact gacttggact ctgaatcctt ttgaatattt tgctaccatc cgttcgattg
      301 caataccgga tatacgcttg gcttctcctt gataaattgc tagaaataaa gctttttcgt
      361 tttctgttac tttgtatcgt tctttccgaa tagctagata attagctaaa tattccattg
      421 caaatgctgc tatatttact gcgtctctct tatttccttt tctagttact accacattat
      481 tcttttctaa agataggtcc tctaaattaa tatttacaac ctcggagagt cttaatccag
      541 atcctaaaat caatgcattg atcgccaggt ctctttctac atctcgttga taatagatca
      601 aagctcgttt gctcaaagtt tttttatatt cattggcaat ataatctaga taattttgtg
      661 tatcttcgtc tagaaataat tttttctcga ttgcgtttgc acgggcagct aacgtagttt
      721 tatctgtgat agttgctact tgatccatag gattattttc taagtatggt tttcctaaag
      781 gattattgga acttttcgaa agatatttaa atagaacctt taatgctgtg atatttctat
      841 tgatagtaga agtagataga cctaagttat tattatcttt gagcttagtt tttgttgtct
      901 ctttttttac attttccttt gtgcgacgtt tcaaatgaga tttgtacaag tttagatcat
      961 aggcagttaa ctgtcttatc gaggtgattg aagtatcggg aacgatagac tcactcagaa
     1021 gccattcata aaagagctta taatttttta gatattctaa agtagttcga ggtgattgat
     1081 ctttatcctc acgatcttga acaaaatctt ttatataatc gggcatatga agtatgattg
     1141 tatctatttt ttgatatatt tctgtatttt tcatgttatt catcctttcg ataagtaggg
     1201 gagaggagta tctctataat tggactatac caattataga gtgttttgtc aattggtata
     1261 ctctgaaatt tattaattta tttcaaaaaa gcagataaat aggtatagat ttaataattt
     1321 aaaataaatg gtatacatga ataggaaagg aaacagaagg aggcaatctt aattttttaa
     1381 attgtctaaa ttatatagaa agaacaatct ttctatataa ttagacataa gagagactac
     1441 ggttgatttg atattaacaa gcgtatatga atgtatatac aaataaaaaa ggggagggag
     1501 aagttaaaga aaattcagag aagtggggca ctcagtagta ttaacaattt aaaaggaatt
     1561 tcttaaagaa aatgggttgc atcctggaga tacaattttt ttagataaag aaaaaattca
     1621 agcaacaatt caaaaaaatc ttaactgctg agattgatgt agcaatatct caatcatcaa
     1681 caaagtacga tcctgccttt caaaagctta ttgataaatg tttattcatt ataaaaataa
     1741 aagaaaaatt tatgtcagct tttttcatca aagtggtaat gataattcgt ctattaattg
     1801 tattttttag gaaatatggt ataattgttt taacgaaaag gtaattcatg atacaccaaa
     1861 aaccactagc tggcgggcta gtggttttct tttacgttct attcagatta acgggtaggc
     1921 ttactgtctt ttttggcaat aattttgcaa tcaagccatt tacagatgta atgcgcggat
     1981 acttctgcta agattgcaaa aaacatatcg aaaaggtaat tcataataca acctcctccc
     2041 cttgccataa taggccgggg tagcagacag cataaatatt ataccataac tgaaaatttc
     2101 attttagtac atttcaatat attgatgaac cagcacaata aaacatgcca tgactaacag
     2161 aaaaaaactt attaaaccag atataacttg taaacatcca actatataga aaacgtaaat
     2221 tttctatata gttggattaa gataacgact atttatttta tcatattttt actataccct
     2281 atacttttac ttggtatatt tatgaataat cgcaaattta cccctatact actagtttgt
     2341 aagttagatt aataaaaata ctaaagttat ttgttctttt attaaataca cctacaactt
     2401 ataaattgat ggtatttaga taacacgaaa gaataaaaat aacagctgat agtaaagttt
     2461 gttgacgatt gctactcaat cgaaagtgag ttagtgcgta tgaacttgct tctgaaaact
     2521 tatgaaatga aagacctttt acatcttgca gaaatcgtta ctgggattaa actaagcaat
     2581 aaaaactaat gttcccctca ttctttgaac ttctactatt tgatttattt attctgataa
     2641 atgacgattt caccttcagg atcttcaaat cccgtataga atttatttaa gatctcttca
     2701 gtatcagtaa taggataggc gataggccac ataccctttg atggttagaa taaactgctc
     2761 aaaatctgta tcgtatgttg gctttagcat attaacaaag gctatctcca aattataaac
     2821 cataagcgtt gaatcgttct taacaatttc aattcttcct aacccaaagt cagaagatat
     2881 aattaccgga cttgccttac ccttcatgtg ggttgttgag attccatatt taaagggaat
     2941 tgtcggtact atcggcggtc tgaaaaacat cccaaaaata aaaaaatctt tcccctgcta
     3001 gtctcctaag tccctttgta gcggatatgg caccataatc tcattttatc gaagtgagtc
     3061 atggtttatc tgttggccaa ccaaaattga tacaatctaa cgatgcaccc tctacggcat
     3121 tctaggggag tgcacttgca ttcacccaat aaaaaccggc agttagcaaa gaacttatgt
     3181 agtcgtatgt tcttactgtt aacatacaag aggtctcctt tccacaattg cttagcagta
     3241 aacgggaatt tacaaagcta atctcttcca ttttcttatc tttgttctaa aagtcccaaa
     3301 tggagcaact gtatttacat gaataaattt atatacttcc catacagccg ttttggttgc
     3361 ctcgtctgcc cattttcttt tgtgtgcagt gaatagatct tcatcactca ttgaatcaat
     3421 catcatgtta atatcatcaa tattacgatt gagaatttcc tctaattctt tcaatggtag
     3481 atgtgcatag gtatttgtaa accacttata taactctcct aactgattcc atttaaattg
     3541 atcagaaggc gttttaacag ataatccatt tctttcatca ttttcccatt ttagaattaa
     3601 attcgtccaa ccaacttgat atgctaaatt ttcagcaggt gttctatcca cttcctcaac
     3661 tcttttatcc ttcaattctt caggaatagt ttcaaattct aaaatatatt tagtataagt
     3721 cctatttatt tcttttttta attcttcttt atttttatat gttctcatta tattacctcc
     3781 ataaattcct aattgtctcc tttaattcat ctataatttc atccacgata ttttaatccg
     3841 ttctacaatg catatctgat atgcattgac tgtctaactc atatgtgaat gatttataaa
     3901 atatcccaac gtctcatcta aagaaatgtt gatcgtcagc aaggagctaa aaaatacgaa
     3961 tatatttctt ttgtagtaaa atcggactgg tttgcatatc attttcttcg taaatatcaa
     4021 aatcatgtta actactatca attactaata aaaactacca ctttaagcgt taagaactgt
     4081 taagtttagt taagtgagga tagttcacaa aatccattgt taaacttcac gaaagtggta
     4141 aaactcaaaa tgctttatat aggattacag catcgctctt tcttcgattg cgcgttgggt
     4201 aaaaaatatt atgaagtaaa aattgacgat gacacgttcc ttacggctca tcagatgaaa
     4261 cagctacaaa aacgaaatga tcaactcgaa gaaaatttaa ttctaaaaaa gcgattgcca
     4321 tattcacgcc tcgctcgacg aactattaaa ggtcaagatt tacctgaaga tcatcctttt
     4381 taggaaattg aagcttttta tgttgcacaa tgcatttata atactacaat gatgttttca
     4441 ccagatattc ttctagggtg cggtgtaatg aaacagatac acttgcaaaa gaaaattcac
     4501 cgcgaattta ctaaaattat gaataattat gttaatcttc cgaaattttt ttccaaaatt
     4561 aagggatcaa gctggtgtta tagattgttt aaggttggca aaaaaataac ttctttttaa
     4621 acaattatag aaaaccgata ctctgttaag ttggttgaca cggtgtcgat ttttatgact
     4681 ttcttattct gaaacttcac taacggacag tacctaaaaa gtctatagta tggacgttta
     4741 cgagtactat tttatcaaaa atgctgctca tttcaactta tatgttttag tgaactaccc
     4801 ccacttag
//
LOCUS       DAFENC010000100         4741 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.106, whole genome shotgun sequence.
ACCESSION   DAFENC010000100
VERSION     DAFENC010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4741
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.106"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(25..1023)
                     /locus_tag="LP493_002801"
     CDS             complement(25..1023)
                     /locus_tag="LP493_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HBL2134896.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKATIETDTTIETKKSKTQS
                     TEQTTTEMKQSVETSASSITESSSEEVKNTLWDTNKASKLETFVTQWGKTLGQEYKSY
                     NLQNNVSLYGTPLPQAVINGDWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVETGE
                     YLGQHVYFFGFQNGQPKVYLTQQNQGNENNYLYFNETQNQQLKQGFSDIVNGQTPQTP
                     VVEESTQQATTTTTQSTSSSGISSWEAAKESVLNNKALWLYDSPDKNVSNTNLISTNE
                     YMKDLMQDENGSYYSINIVTDDDGNTTMAGGKQFRVYTDGRISQRIGMTNNFQMIK"
     gene            complement(1098..1394)
                     /locus_tag="LP493_002802"
     CDS             complement(1098..1394)
                     /locus_tag="LP493_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134897.1"
                     /translation="MAKLIVLGGLIYGGYWLYQYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHTGYRHYWERID"
     gene            complement(1387..1680)
                     /locus_tag="LP493_002803"
     CDS             complement(1387..1680)
                     /locus_tag="LP493_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134898.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            complement(1826..2377)
                     /locus_tag="LP493_002804"
     CDS             complement(1826..2377)
                     /locus_tag="LP493_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HBL2134899.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFLRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            complement(2551..2850)
                     /locus_tag="LP493_002805"
     CDS             complement(2551..2850)
                     /locus_tag="LP493_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HBL2134900.1"
                     /translation="MLETAIEVLEKCAQLVTASEEWGYESVTMEKEEIEMGMLPEDVH
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTDE"
     gene            complement(2877..3143)
                     /locus_tag="LP493_002806"
     CDS             complement(2877..3143)
                     /locus_tag="LP493_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBL2134901.1"
                     /translation="MDSLPVELQALCWNLIDQNVQKQFPLDYLQIFEFSTEKGNQKLV
                     HRQEEPEERKEYLISPKLRLKSVSQKIWAIDSGEYQTMLLPEEY"
     gene            3490..4173
                     /locus_tag="LP493_002807"
     CDS             3490..4173
                     /locus_tag="LP493_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134902.1"
                     /translation="MTTEHFDLANPVTKVDDIPDYEMYSQTIDSLNKRFGNRVLKGIK
                     IGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDDEVKDMDPAIVIPQYFAQLSE
                     ALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQFLPILDQVIKNKLAFELNAKSAYLY
                     DNLALYEYVIDLYLSRGGTLFSVGSDGHYLEHFRFHFDDLFALLKANGVTELAIYQKG
                     KRIMVPLPV"
     gene            complement(4210..4707)
                     /locus_tag="LP493_002808"
     CDS             complement(4210..4707)
                     /locus_tag="LP493_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2134903.1"
                     /translation="MNNQITLAYLDYDDLDALQVVSVVSFYESFIDGADPLDMQGYLQ
                     TQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLG
                     QRLLDEANRYAKTKQKRYLRLTVYEKNHAGIRFYERHGFKKIGIKHFPLGKQDRICPI
                     LEKEI"
BASE COUNT         1404 a          907 c          694 g         1736 t
ORIGIN      
        1 ttctttgata aataatattt tcaattattt aatcatttga aaattgttag tcattccaat
       61 acgttgagaa attcttccat ctgtataaac acgaaattgt tttccaccag ccatggtcgt
      121 gtttccatca tcatccgtta caatattaat tgaatagtag cttccatttt catcttgcat
      181 tagatctttc atatattcat ttgtgctaat taaattagta tttgatacat ttttatcagg
      241 agaatcatac aaccataaag ctttattatt tagcacagat tctttagcag cttcccaact
      301 tgaaattcct gaactacttg tagattgtgt cgttgtagtt gttgcttgtt gagtagattc
      361 ttctactact ggtgtttgag gagtttgtcc attcacaata tcactgaaac cttgttttaa
      421 ctgttgattt tgagtttcgt taaagtacag ataattattt tcattacctt gattttgttg
      481 cgttaaataa actttaggtt gtccattttg aaaaccgaaa aagtaaacat gctgccctaa
      541 atattctcca gtttctacat cagaataaac tgctactaaa ttgaaatctg catgaccagt
      601 tccatcttct gaccattgta cggtaactgg tgcttcattg attgccattt tccaatcgcc
      661 attaatcacg gcttgtggta aaggagtgcc atacagactt acattattct gaagattgta
      721 gcttttatat tcttgaccta atgtctttcc ccattgtgtg acaaaagttt ctaatttgga
      781 agctttattc gtatcccaca aagtattctt aacctcttca gaagaagatt cagtgattga
      841 acttgcactt gtttccacag attgcttcat ttctgttgta gtttgttcag ttgattgcgt
      901 tttacttttt ttagtctcaa ttgttgtatc agtttctata gtcgctttag tcctcgtatt
      961 ctcagatgta caaccagtga ataaaattcc cattcctatt agtaataaca gccatttttt
     1021 cattatattt ccccctttca atttctccct cacgtactta ttctatcaga caattaattg
     1081 atctaaatgg taatctttta atcgattctt tcccaataat gtcgatagcc cgtatggcag
     1141 cggtctcttc cttgaggact ctcagatgga ttaaaactag tagaaatttc ccttccacat
     1201 cctctacagc gataagttct cattattttt gggctattag tattattttt cttagttaga
     1261 gctatgagtc caactatgat taccccaact gtcttaatta cttttccttt atctatattc
     1321 ggatgcgcaa gcatatattg atataaccaa tatccaccgt aaattaaacc acctaataca
     1381 atcagcttag ccatgtactc gtctcctttc tttttgttta attacttttt gaatccatct
     1441 tgcagagaaa ccataaactt ctgtcaattg acggatatct acagtttttt cctgttctat
     1501 catgttttcg attctttttc taactaactc acgatcgtac attttcattg gaaaagaaat
     1561 ctgttgccct cgaaaagcaa gataaaattg atagagcaat tctgaatcca gttccatttc
     1621 ctcaaaaaag tcattcatac ttttataaga gttactcaaa caagtttcat caatctccat
     1681 ctacacaccc cctgttattt tttacataat gaaaatagca tattactggg tacattgata
     1741 attcatataa catgtatcat cacatgtatt tttaaagtca aaaagcatgt aaaactactt
     1801 ataagtaaca tgagaaaata aaatgttatt tttcttgaaa taataattga ctatctgcca
     1861 attgccattc attacgaaca tgaatactta gtgggtggga taacttacct tctgcattta
     1921 tcaatacttt ggtcatcttc ttttgtttcg cactcaattg atcgtaaata gtctttgctt
     1981 gttcataagc cacttgactc gtcgctgtaa tcgaaccaca agcaaaaata atggtattga
     2041 ttttcttttc tgtaaaaaca gtcgttaata tttccaaaga ttgttcatca tttcctcgaa
     2101 gaaatacccg aggacttttc gcttttgtgt acgaaaaaag attcacagca ataaaaccag
     2161 taaatcctaa ttgtcggata ttcttttcga ttaataacat actcaaatca ttcgtaaatg
     2221 gttctgtatc tgttggacga atagtaatga ctactgctaa tttatcttcc gcttcttttc
     2281 ctttgatcgc ccattgtcgt ttgaaaacat agcgatgggt atgatgagga tctcgccaaa
     2341 cttctgtttg tgtggtcact aattcttttt caatcatctc tttttctcct atgctatttt
     2401 ttgttcaagc acttcaatta ccattgccgt tataagtgtc aatactagtt gaaaatattt
     2461 catattcttt ctcctttttt cttcagaatt tgatgaatcg cggtaaggat atcttctaaa
     2521 catttcgcaa tcattctcaa ataatcgatc ttattcatcc gttcctccaa tctgactcca
     2581 aaccaatcgt ccttctacca gtaacccacg aacaaattct cgctggctgg taatatctgt
     2641 aatgaaataa actacatagt cttttccatc ttctggtgcg caataaatat aaagatgtgt
     2701 catcactaaa cgtggtagat gaacatcttc aggaagcata cccatttcaa tttcctcttt
     2761 ttccatcgta acggattcat agccccactc ttcagaagca gtgaccagct gtgcacactt
     2821 ttccagtact tcgatagccg tttctaacaa gtcctttcgt tcctttcttt tagatactag
     2881 tattcttctg gtaataacat cgtttgatac tcacccgaat caatggccca tattttttga
     2941 gacactgatt tcaaacgaag cttaggtgaa atcagatact cttttctttc ttccggttct
     3001 tcttgacgat gaaccaactt ttgatttcct ttttccgtag aaaattcaaa aatttgaaga
     3061 tagtctaaag gaaattgctt ttgaacgttt tgatcgatta gattccaaca taaagcttgt
     3121 aattccaccg gcaaactgtc cattactccc tttgtgacat aacgttatcc tttattttga
     3181 aacatttctt ttccctcctt tgccataaaa atagcccaat cttctattaa agaagattgg
     3241 gcttcatgga tataatatat atttgtaaat aaagttaatt cagttataat tatcaaaact
     3301 acacaattat taaagttttt catatctctt tgtttagtaa gtttttctaa atcttaaccc
     3361 gtggtgctag ttaatttttt cctagaggaa aatgtctaaa catgttggta aatcaacaaa
     3421 aaaacgcata tagtagtctc aaaactccca agaaatgagg actatttaac aaactacgat
     3481 ggttacgtcg tgacaactga acattttgac ttagccaatc ctgttactaa agtcgatgat
     3541 atccccgatt atgaaatgta cagtcaaaca atcgatagct taaataagcg ttttggcaat
     3601 cgtgttttaa aaggcatcaa aatcggttac atcgcttctg aaaaggatcg gatcatcgac
     3661 tatttagccg ataaagatta cgatttaaaa ttactcagtg tgcatcataa tgggcaattt
     3721 gattatttag atgacgaagt caaagatatg gatcctgcta ttgtgattcc tcagtatttt
     3781 gcacaacttt cagaagcact agttgttata gaagcagatg tctttgctca ttttgactat
     3841 ggttttcggg tatttggtct atccgttgct gaatttaaac aatatgaagc gcagttttta
     3901 ccgattctag atcaagtaat caaaaataaa ttggcattcg aattaaatgc taagagcgct
     3961 tacttgtatg acaatttagc gttatatgaa tatgtcatcg atttatatct ttcacgtggt
     4021 ggtaccttgt ttagtgttgg atcagatggg cattaccttg aacatttccg tttccatttc
     4081 gatgatcttt ttgctctgtt aaaagcaaat ggtgtgacgg aattagcgat ttatcaaaaa
     4141 ggaaagcgaa ttatggttcc attaccagtc taaaaaaacg tcctcagcat caaaagtgag
     4201 gacgtttttt tagatttctt tttctaaaat cggacaaata cgatcttgtt ttcctaaagg
     4261 aaaatgtttg atcccgattt ttttaaatcc atgacgttca taaaaacgaa tacctgcatg
     4321 atttttttca taaacagtca aacgtaaata acgtttttgt ttcgttttag cataacgatt
     4381 cgcttcatcg agtaaccgtt gccctaaccc tttgttttga taatctttga gcagatagag
     4441 ccgttgaatc tctatagcat ctttttcatc attgactttc atataaccaa tgagtatttg
     4501 atgatcctta ataccaataa atttactggt tgactgtgcc aattctactg ccaatatttc
     4561 agttgtcaat tgtgtctgta aatatccttg catatcaagt ggatctgcgc catcgataaa
     4621 cgattcataa aaactgacaa cacttacaac ttgtaaagca tctagatcat cataatctaa
     4681 atacgctagt gtgatttgat tgttcatcta actcctcctt ttgacatagt atactataaa
     4741 t
//
LOCUS       DAFENC010000101         4630 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.107, whole genome shotgun sequence.
ACCESSION   DAFENC010000101
VERSION     DAFENC010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4630
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.107"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            172..516
                     /locus_tag="LP493_002809"
     CDS             172..516
                     /locus_tag="LP493_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBL2134904.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            517..936
                     /locus_tag="LP493_002810"
     CDS             517..936
                     /locus_tag="LP493_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBL2134905.1"
                     /translation="MTTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVIFEPGCRNHWHVHKDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1028..1378)
                     /locus_tag="LP493_002811"
     CDS             complement(1028..1378)
                     /locus_tag="LP493_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134906.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1344..2675)
                     /locus_tag="LP493_002812"
     CDS             complement(1344..2675)
                     /locus_tag="LP493_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HBL2134907.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            2931..3497
                     /locus_tag="LP493_002813"
     CDS             2931..3497
                     /locus_tag="LP493_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBL2134908.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3642..3729
                     /locus_tag="LP493_002814"
     tRNA            3642..3729
                     /locus_tag="LP493_002814"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3674..3676,aa:Ser,seq:cga)
     gene            4063..>4630
                     /locus_tag="LP493_002815"
     CDS             4063..>4630
                     /locus_tag="LP493_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HBL2134909.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSN"
BASE COUNT         1681 a          778 c          890 g         1281 t
ORIGIN      
        1 ataaaaaaag cgttagcaac tatgcttaaa aagcatatcg actgaataaa ctaagcattg
       61 gacaggctga aagactacat ttaaaatgaa atgcgaagaa acaatagaaa ataaagttgc
      121 cttagaacca tagttgaatc acctaacagt cgtgaaggga gaataagaga aatggcagaa
      181 aaacaaaccg caggacgaga tcaattagga gattttgcac caaaatttgc agaattgaat
      241 gatgatgttt tatttggaca agtatggtcc agagaagaat tatctgctca tcagcgtagt
      301 atcatcacca tatctgcatt aatttcagga ggaaattttg aacaattgcc agctcatctg
      361 aagattggca agcaaaatgg cattactagt gaagaaatag cagaaatcat tacccattta
      421 gctttttatg taggatggcc aaaagcttgg tcagctttta gtttagcaaa agaaatctat
      481 ttagaagaaa atagcgaaga taagaaagag gcgtaaatga cgacaaaaca cgaagaaata
      541 cacaatggcg tgatttttcc agcaggtgaa aaaaacgaag cttacgctca agtatttacc
      601 gggcaaagct atctgaatat gttagtgaat gatcccgaag tttctgttgg tgtaggtaat
      661 gtaatttttg aaccaggttg tcgcaatcac tggcatgtcc ataaagacgg ctatcaaatc
      721 ttacttgtga ccggaggaga aggctggtat caggaagaag gaaagccagc aagacgatta
      781 atggctggag atgtcgtcgt aacgcacaaa gggattaaac attggcatgg tgcgacaaaa
      841 gacagttggt ttgaacattt ggcgatcact gctggtaatt cagagttttt agaacctgta
      901 acagatgaag tgtatgaagg attggaaaat caataatgtc aagcttgaac agctcctgaa
      961 agtagatttt aatcgaactt tcaggagctg cttttttgat tcagtctttt ataaatagaa
     1021 aatagggtta ataataggaa tgagaagcac gtcgaaagat cttaatattg ataatcggct
     1081 gggcatacat gatttccacg tcatcaatca aactacctaa cagatgataa tcttcccgat
     1141 catgtcgggg attacctaat agttcttgat agtagatttc catactaggg tcccgaggat
     1201 tgttcagcaa atcagcaagt acatctaaat cttctggctg agtttctgcc gtaccctgta
     1261 tctctatgaa aagcccttcc tcagcaaatt ctactccaat acgtatttca gttatttcat
     1321 gggaatataa ataagtaaga agctcatcga tgattctttt tgataattct ttttccaagt
     1381 gtcttttttt cctttctgac agcggtaaag ttatctagta tcggtacaag gatacctgca
     1441 acgaaaccag ttgaaaaacc actgttatat agatttagtc ctccgtgcaa agtgctgacg
     1501 ttatggacaa gagcaatatg tagtacacca gctattacac cgtaaaaact gccgtaaaaa
     1561 ccgcttatgg gcgcgagacc tgtcccaaac acagctgcaa caagcatgcc agtactggtg
     1621 atctcatgaa aagttccaaa caaagaagca ataaatattc cgactagtat cggaaaactg
     1681 ttttttaaat gacaaccaaa agcactgaaa cccaccgcag ataaaatagc accgatgaca
     1741 ggtccattta actgaccgcc aaccagcaaa acataagaag acagcatcag accaactaag
     1801 cctatgttga tcaaagtagc accaatacca gaattagcaa tgaaatcagt tgtcaatttt
     1861 ccagatgaat cgaaaatttc tcgaatcccc aaaagccgaa aggaattata atagaaacca
     1921 attccgactg tcagcgaaaa aaagccaaaa ataatccaaa tgagaggaaa gtgatattca
     1981 ttgaaaacca atgtattttc gacgattgaa tagctgaata acctcaaaac agcagtaaaa
     2041 gtcatcgcaa tcaacccaga ggtgaatcca atattataaa gtgtgaatcc acgatggaaa
     2101 actaaagttt gagcagctaa gggcggaaga agtagaccaa ttgctatgcc agctaaattc
     2161 cccaataaaa tacctatcag taaaggaaaa cgcataccaa aagtgatata actaacgacc
     2221 ggtgataatg cgctaccaaa cagtccgatc atgatgtact gagaaaaagg tttattgaca
     2281 aatacagcgt atagatacac acctaaaatg attgagatag aattataaag gtttttgcca
     2341 aaaaaagaga aaccggtaac tgttagaatc gaagcaaata agggaccgtt taaaatcacc
     2401 ttgtgccgat aagctaaaag cacagaaagt aaggtcaaaa tccctacatt tatgaatgcg
     2461 cttccgaaac cgcctaaagc aaaataatct gtcaaaagat tgcttggcga ggtaagaata
     2521 gttagcaatc cactccaatt atcagtagga gtattagaaa gcaagccaat aaaaagaaaa
     2581 aaaacacctg taaaaccaag ataaaaatac tttcttttct gtgaaacgat tcgtttttga
     2641 ggatgaatat aaataacgtc agtttcgttt tccattacac accttctttt tcattttctt
     2701 taactataac ttgaaatgaa agatttggac aactatcatt taggtcaaaa ctaaaaatgt
     2761 aagggaaccc attgaattta accaaatttt tttaattttg caaaaaaaag ttaaagaaga
     2821 ctgaaaaaaa atttaaaata taacgttttg agtaaaatgt ttgcaaaaaa tgctaaaaat
     2881 agggtacaat aaaacaacat atactgcagt aaagaagtgg gggagtttta atgagaagaa
     2941 aagtctatac caaggatcaa attctaaaag ctgcttatga tgttgttgca aaggaagggt
     3001 ttaaaggatt tactgcgaga aatattgcta aaaagatggg gatttcgaca cagccgattt
     3061 atctggaatt caaaaacatg gaagatttaa aaaatacgtt gctggattct atctttgaac
     3121 aactaaaaga agatgttttc cctattgaac gtactggtga taaaatcatt gatctcggtt
     3181 tgaactatat ctactttgca aaaaagcatc atagtcttta catggcattg tacattgatg
     3241 aacatgggga cggaaagaaa atgcatgatt tttcatacaa ttatttccgt gaaatagtta
     3301 aagaagatga aagatacaat caattatcgg atgaatatgt cgatgctctg catactggta
     3361 catgggtagc agtgactggc ttagcgtcat tgatgtcatc aaacatcatg catccaacag
     3421 aagaacaaat cattgcactg atcaaacgga caattgactc gattttagca ttagataatc
     3481 ctgaaataat cagatagtgt tctatcagta tgaatttgat cggtaagtcc gttggctgca
     3541 aactgtcaat ggactttttt gctaaaaaaa gcgatttctg ttatttatct attagaaata
     3601 ggcttgacat ttcgtgaaaa aagtttaaaa atagtactta cggaaggttg gcagagtggt
     3661 aatgcaccgg actcgaaatc cggcgaaccg gctaataccg gcgcgcaggt tcaaatcctg
     3721 taccttcctt atatcaacga ttagaggttg tgaagaagct gtcctgcatc aagtaataag
     3781 aacggccaaa caaaaatagc ttttcctatt ttttcgtttg attgggctta ttaccgcaga
     3841 tgcaagcttt tgaacaccgt ttgttcggaa taaggggctg tgacaagact tttgtcacag
     3901 ccccttattg ttgtactttt aacctacaat attttttgat tccccctgag tactattttt
     3961 tataaatgct agtaaatcaa tcttctttgg cctttttttg ataaaaaaaa tactagatgt
     4021 aagataaaag tgtaaaaacg atttgtttta ggaggggaaa cgatgtgtac cgcaatcact
     4081 tatgcaacga aagaccatta ttttggaagg aattttgatt atgagatgtc ttataatgaa
     4141 gtggtcacta ttactccaag aaattatcgt ttcgatttta gaaaggtaaa aaatttagat
     4201 aaacattatg caatgatagg aatagcagct ggggtatcca actatccact ctattatgag
     4261 gctacaaatg aaaaagggtt gagtatggca ggactgaatt ttcctggcaa tgctgattat
     4321 aaagaattac aagaaggaaa agataacgtt gcaccatttg agtttattcc atggatacta
     4381 gggcaatgct caaccataga cgaagctaaa gaattattgg ctactatcaa tctagtcaat
     4441 atcgatttta gtgaaaaact acccttgtca cctttacact ggttattagc tgataaagaa
     4501 aaatcgatag taattgaaag tatgaaagat ggacttcatt tatatgataa tcctgtcggt
     4561 gtgttgacaa ataatccgcc atttgattat caattattta atctgaacaa ttatcgctcg
     4621 ctatcaaatg
//
LOCUS       DAFENC010000102         4590 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.108, whole genome shotgun sequence.
ACCESSION   DAFENC010000102
VERSION     DAFENC010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4590
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.108"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            186..2855
                     /locus_tag="LP493_002816"
     CDS             186..2855
                     /locus_tag="LP493_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HBL2134910.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEVSFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEKPRNTHRRRRRK"
     gene            complement(2946..3566)
                     /locus_tag="LP493_002817"
     CDS             complement(2946..3566)
                     /locus_tag="LP493_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBL2134911.1"
                     /translation="MFLINATDEILSVNKVFYTVPAEKMSRVSSDINTITSRIGLTKA
                     MHMVLKYNQEDPPVPKTYEAIDLIIVDEIDRLKLQHLEQLRDIYDRNDLAMVLIGMPG
                     IEKRLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWADLGIDIKLEDFSDYEAITTI
                     IKITKGNFRLIHRLFAQIDRILRINQMDKITVEVVEAARDSLVIGI"
     gene            3680..4219
                     /locus_tag="LP493_002818"
     CDS             3680..4219
                     /locus_tag="LP493_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134912.1"
                     /translation="MKKLFSALFILLFGFIGIGTSGNIVKASTMVEQTSEMAKTFSQL
                     TPEEQSYFKSKGFSDKDTFYTQKIEPQDPKTRFSANVLRLTASTKKITNTQGRTEYII
                     TSPNSAMYRISTRLSLGSAKSYTQTVNLANSYGYGGGMYFTFTGKRQYYSVKLAMQVY
                     NTFGVGSVSCTAGGLTIGK"
     gene            4216..4554
                     /locus_tag="LP493_002819"
     CDS             4216..4554
                     /locus_tag="LP493_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic metallochaperone ArsD family protein"
                     /protein_id="HBL2134913.1"
                     /translation="MIISYYVLNRSDDEGLFVFQSLHEDTMLKEFYNRIKNKQIETNL
                     YFLSDSILPFISNPKILNLLQTKDLKSLPIIVIDEEIVKYGAYLSVEELEKLTNIGMS
                     IQEDNGVHGT"
BASE COUNT         1420 a          790 c          860 g         1520 t
ORIGIN      
        1 atttttaagg gtgggacttt tgattcctac cctttttttg cgtttatttt tgttatacga
       61 acaaattatg aagttattta ttctaaattt tatttttttg tgaaaattag actcttttta
      121 agcagagaaa aacaaggata tgataaactg aatacaactt catagaaatt tggtggaaaa
      181 taaatatgaa aaaaaattta aagtcattct ttagagaaaa cggacgctac gcagcagcta
      241 gtttcctgat tccgtttttg attttagcac ttgtttatct aagtatcggg atctatcctg
      301 gaagcagcag aagtattttg gcaagtgatg ccttttcaca gttttctaat tttcatgcca
      361 gcttccgaaa tgttcttctt ggaaagcaaa gtatttttta tacatggaat gcttctctag
      421 gattgaatta tttatcttta atttcttact atctaggcgg gatcttcacg ccactggtgt
      481 tcttttttcc aaaccagatg atgccagatg cactgtatgt tctgactttg cttaaggtcg
      541 gctgtgccgg attggctttt tggtttcttg cacgtacgtt caagattcct cgctgggggc
      601 atgttgcact tagcgtcagt tacgcattga tctcatttat cactgcacat tcggagatca
      661 tcatgtggct ggatgcattt gtttatcttc cattagtgat tttggggatt catcgtgtta
      721 tggatcttaa acggccgaaa cttttattta tcagttattt actcttgttt ttatccagtt
      781 tttatatggg ttttatgatt ggcgtatttt ctttcttata ttttatcgcc cgtctattga
      841 caaactggtc agaatataaa aaaacgattg ttccttatgg tatcacttct ttactggcag
      901 gcggcgcttc aatgatcatt gtattgccag cagtgctgga tcttcggtca aatggcgagg
      961 cactgagtca gatcactacg ttgaaaacag aagcgacttc ttatctggat ctaatcatga
     1021 aaaatatgat tggtgtttat gacacgacaa aatacggatc gattccgttc gtttacgcag
     1081 gtctgctacc attagtcctc tgtctgtttt attttgccag tcggaaagta ccgttgaaaa
     1141 ataaattttt gtacggcagt cttttcgcca tacttatcgc aagtttctat cttgttccat
     1201 tgaatttgtt ctggcatggt atgcatgcac cgaatatgtt tttattccgt tatgcctatc
     1261 tgttctcttt cttagtgctc ctgcttgcag gaaaaggatg ggaaaagata gaacaagacg
     1321 atcgtgggct gttgttagga atcattttgg tcgtagctgc tctctttgcg gtggcatggg
     1381 gcatcaaacc tgaaggaagc tacacctatg tgacgatgac ttcctttgta ttgacagtgg
     1441 ttttcttagg gatttatgct tttgctgtgg gattttatca gcataaaaaa ctttcattca
     1501 atcatctgag tatattgtta ttattgatca tgtctgctga agcactggtc aatacgaaca
     1561 gtatgatcca tggcattctt gatgattgga attatgcttc ccgcagttta tatactgatc
     1621 cttatcctga cttgaaagct cttgtaaatg aaacaaaaaa agattccgac tcgttttacc
     1681 gcttggaaaa tctggatcca gtatctgcaa acgattcgat caactatggt tacagtggta
     1741 tcagtttgtt ttcttctata agaaatcgta attcttcctc ttacctggat aaattaggtt
     1801 tccgttcaag agggacaaat ttgaatatcc gttataacaa taatactttg ctaatggatg
     1861 ggtttacagg aatcaaatat aacatttcta aaaacgaaag cacgttcagt aaatatggct
     1921 tccgccaagc tggtcaaagt ggcgactata cactgtatca gaatgtcaat gcattgccac
     1981 tagcatttac tgcaccgttg tccgttaatg atgttgagca gccagtgaca gataatttga
     2041 ccagtcagac aaacttgatc aatacattgt ctggtttaaa tgaacagtat tttacattct
     2101 atacacctac tttgaagaat cagttgaata cgacgatcac aaagacaacg actggcgtca
     2161 cttactcaga aacagcagat aaccagccaa aagagctcac ttgggaagtc catgtgcctg
     2221 caaatacaca agcttactta agtttgttcc caaccaattt tgcacaatta gaaagttcta
     2281 gtgcgacgat cactgtcaat ggtacatcgc gaaaaacgca aatcaacatt tctggtcaat
     2341 actatgatct tggctattat cctcaagaga caacagtgac atttactgca agtttttatg
     2401 gaacgaaaga agtaagtttc atggagccta aagtcgttgg tctagatgtt gtagcctatc
     2461 aagccgcaat gaatcagatc aaagaaaaag gtgtcgaaat ggaagccact ggcagaaaag
     2521 cttctgggac tgtaaatacc gctgaagatt ccatgttggt gacaactatt ccttatgaca
     2581 aaggatggaa agctaaaatt gatgggaaac cagtcaaggt cagcaatttc aaagacgcat
     2641 tcttgatgat aaaagttcca gcaggtaaac atactgtcac tttcagttac ttgcctgaag
     2701 gatttacgat aggtgcaatc ctttttgtcc tatgtattgc attgtttatt ctttatgtct
     2761 ggtaccttga ccgcaatcgc cccttttatg gcacgattga tccagcaata gaagaaaaac
     2821 cgcgaaatac acacagaaga agacgaagaa aataaagaaa cgatggaatc tgtgtcactc
     2881 ttctatttaa atggcaaaaa tttcaatctt taaatgacaa aaaccacctg atttttggtg
     2941 gttttttata tacctatgac taaactatct cttgctgctt cgacaacttc tacagtgatc
     3001 ttatccattt gattgattct taaaatccga tcaatctgcg caaataaacg atgaataagc
     3061 ctaaaatttc cttttgtgat cttaatgata gttgtgatag cctcataatc agaaaaatct
     3121 tctagcttga tatcaattcc taaatctgcc catttgtatt ccaaaatatg atgtgtttcg
     3181 tccttactaa ggttatcaaa ttcatgtgca aatcctatgc gagagtaaag ctgcggataa
     3241 cgagacaatc ttttttcaat accaggcata ccgataagaa ccattgccag atcatttcta
     3301 tcgtaaatat ctcttagctg ttctaaatgc tgaagcttta aacgatcaat ttcatcgaca
     3361 ataattaagt caattgcttc ataggtttta ggcacaggag gatcttcttg attgtatttt
     3421 agtaccatat gcattgcttt agtcagacct attctactag ttattgtgtt aatatccgaa
     3481 ctgacacgag acatcttttc agctggtaca gtataaaaaa ctttatttac acttaatatt
     3541 tcatctgttg catttatcaa gaacaagaaa aagtctgaat attcaaaaaa aataacggtg
     3601 tacattttta aaaggagatg tataatcgag atttagaaag cgttttcctc aaaatttaat
     3661 gaattaggaa gtgattacta tgaaaaaatt atttagcgca ctttttattc tgttatttgg
     3721 ctttattggt attgggactt ctggaaatat agttaaagct agcacgatgg ttgaacaaac
     3781 aagtgaaatg gcaaaaactt ttagtcaatt aacaccagaa gaacaaagtt acttcaaatc
     3841 caaaggattt agtgataaag atacttttta cactcaaaag atagagcctc aagatccgaa
     3901 aacacgtttt tctgcaaatg tattgcggtt aaccgcatct actaaaaaaa ttactaatac
     3961 gcaggggcgg acagaatata ttataacaag tcccaattcg gcgatgtatc gtatttctac
     4021 acgcttgagt ttaggtagtg caaaatcata tactcaaaca gtaaatctag ctaattctta
     4081 tggttatggt ggaggaatgt attttacatt tactgggaaa agacaatatt acagtgtaaa
     4141 attagctatg caagtttata atacatttgg tgtagggtca gtctcttgca ctgcgggagg
     4201 attgacaata ggaaaatgat aatttcttac tatgtcttaa atagaagtga tgatgaagga
     4261 ctcttcgttt ttcaatcatt acatgaggat acgatgctaa aagagtttta taatcggatt
     4321 aagaataaac agatagaaac aaatttatat tttttaagtg actctatctt gccttttatt
     4381 agcaacccta aaattcttaa cttgttgcag acaaaagatt tgaaaagttt accgattatt
     4441 gtcattgatg aggaaattgt aaaatatggc gcttatctaa gcgtagaaga attagaaaaa
     4501 ttaactaaca ttggaatgag tattcaggag gataatgggg tacatggaac atagaatgaa
     4561 tatgcacagt tgagaacgga atttgacatt
//
LOCUS       DAFENC010000103         4477 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.109, whole genome shotgun sequence.
ACCESSION   DAFENC010000103
VERSION     DAFENC010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4477
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.109"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(832..1125)
                     /locus_tag="LP493_002820"
     CDS             complement(832..1125)
                     /locus_tag="LP493_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HBL2134914.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            complement(1528..2706)
                     /locus_tag="LP493_002821"
     CDS             complement(1528..2706)
                     /locus_tag="LP493_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL2134915.1"
                     /translation="MEKTDRFKKQISSTGRITWYFQAYRTTRRGFNSKREAQLAYLEM
                     EKQQRLKKKIVASNDKFSVVGEQWFQYYRSLNEQKEITYDKREEQLKIIVRWIGDKKL
                     SDLTPECLQELLFTLKECGVNGTNVGYAKNSLQSLIQVLNMIFKYCQRKNLISENPMK
                     SVRMPKYQLTVTDLKEAINNIEDKFLTVDELRTFLNYGIVHEELPMSVLFHVLFYTGC
                     RVSEALALQPGDIDFKRNEILFYKQTAVKGKSKDFRIETTKTVSSARRVLVTPLVMEK
                     LQQLIKALGEMRQHYRFIIEETYLFVYLDSSKRGVPYRREYVNDHVKRCVNRSGINKP
                     FHTHLARHTMASLVAEHCSWEVLKDRLGHTDQTTSKIYRHLTSNEKVKPLIAFSSLES
                     "
     gene            complement(2810..3124)
                     /locus_tag="LP493_002822"
     CDS             complement(2810..3124)
                     /locus_tag="LP493_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2134916.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            3231..3446
                     /locus_tag="LP493_002823"
     CDS             3231..3446
                     /locus_tag="LP493_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134917.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWK"
     gene            complement(3746..3988)
                     /locus_tag="LP493_002824"
     CDS             complement(3746..3988)
                     /locus_tag="LP493_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2134918.1"
                     /translation="MKQNKRYIPFIPLTTIKAAASGDSIAMSIVLSKYQNYISRLAMK
                     PVYEEEKGMVMYVDEYMRRQLETKLIEKILEFDTTR"
     gene            complement(3975..4403)
                     /locus_tag="LP493_002825"
     CDS             complement(3975..4403)
                     /locus_tag="LP493_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBL2134919.1"
                     /translation="MGDSEETHIQHTFDSFCKKVVCNEALNIQKKYARFRQRQISMEI
                     LEQKGLGTEFYYLEPNLNSSGTFIVLGMKIFISNEELANAIAALPSQRQEIIFMSFFI
                     GLNDREIGDIIGKSLGSVWYQRQMALEELGKYLGVKYEAK"
BASE COUNT         1418 a          841 c          663 g         1555 t
ORIGIN      
        1 ataaaaaatc atcaaataat cctttacacg ttattctaaa tttaattttt attattttat
       61 tgatgtatag aaagtttggg gctttttttc tctttttatt ctaaggttat tttagtcttg
      121 tcctttaata caaagatttt atttttaaat aaaaaatact ctttttttac gattattgaa
      181 aaaaaaagat aaaacttgat taattgaagt attgcttaaa tttggaagct atgagggaag
      241 aataaaagag ttaggacggg attatctact atttttcttt gttttaaata tttgttatct
      301 ttgaacataa aagagaaatg tgtcgactgc agtgttgtgt ccctcatcac gaataaacgg
      361 tgttcaatta gctgatcttg tattcactta aaaaatggta aagtacgagt tgctattccc
      421 cattttcaat tttctaacgc tcaggacaaa atactgtttt cacaacctca ttggaataaa
      481 agcatatata ttgtttcaag aacgaaatct tgttatcttt ttaaagggca tctgtccaaa
      541 atctaatttt aggaggtacg ttttggtatt tattcgtaca aataaaagag aattatcttt
      601 attcatgtaa cgcatccaat tgattttttc atgtacgctc ctggaacgat tttactgacg
      661 attgcttatt taactgcgaa tcgctcatta gcttttatca tagctatcca tattttgaat
      721 aacgttcttg gctttgtatt atagatacag atgacaaaaa aagttcaagt atgcggtgta
      781 gaaccaatat cgcatacttg aacttttttc aatgagtata aattaaaact tctaattttc
      841 aattcccatc atctgatatg cccgaccgtc tgaacttctt ttgaaaaagc caaatgtgat
      901 tagataacgt ctttgttcga cataatcgcc actagaaaat acgttcagca gtatcgaatt
      961 aacctctgtt tctgtataag tcactccatg gtcaaagcgt ttcaagactt ctttcaatag
     1021 gatgtatttc ttttttgttg aacttggtac ttgttttact tttccatcat tcatgaatgt
     1081 gtctaaaact ttcatctttt cttgctccgt ataagtataa accatcttct ttctcctttt
     1141 gattctaaga atactccatt tatgttagaa tattctggat tttttattaa agcggttact
     1201 cttaagaaag atattatcat agtgctcttt tttttactac tacttatagg tagatttatt
     1261 ctaatccatt attctcccct accaataatt aaagaaaaaa ctggatcagg gtgttcaaat
     1321 tacatgctaa gaaaaaagaa cccttgaata ccaagggttc tttctcagtc tgataacaat
     1381 gattaacgac ggatttcttt gatacttgtg aaaagtcgtt aaagtattga tataaaagga
     1441 tttttattac ctctgactac atattgacta atttgttaaa aaatcgtttt tcaagaatcc
     1501 tgtaatacca gtgctttcac cgttttttta actctctaaa gaactaaaag caatcagagg
     1561 ttttaccttt tcatttgacg ttaagtggcg ataaattttc gaagttgttt ggtcagtatg
     1621 gcctaagcga tctttcaaga cttcccagct acagtgttcc gctactaagc ttgccattgt
     1681 atgacgagct aaatgagtat gaaatggctt attaattcct gagcgattca cgcaccgttt
     1741 gacgtgatca tttacatact ctcgacgata aggaacacca cgtttactag aatcaagata
     1801 cacaaacaaa tatgtttctt ctataataaa cctgtaatgt tgcctcatct cacccaaagc
     1861 cttaatcaac tgttgtagct tttccataac tagaggagtt actagaactc gtctagcaga
     1921 actaactgtc ttagtagttt caattcgaaa atccttactc ttacctttaa ctgccgtttg
     1981 cttatagaac agaatttcat ttcttttgaa atctatatct ccaggctgta gagcaagcgc
     2041 ctcgctgact cggcagccag tgtaaaatag aacatggaaa agtacagaca tcggtaattc
     2101 ctcatgaaca atgccataat tcaaaaaagt tctcaattca tcgacagtaa gaaacttgtc
     2161 ctcaatatta tttatggctt cttttaaatc agttaccgtt aactgatatt ttggcattct
     2221 cacagacttc attggatttt cacttatcaa attctttctt tgacaatatt taaaaatcat
     2281 atttagaact tgaataagtg attgtaaact atttttggca tagccaacat ttgttccatt
     2341 aacgccacat tcctttaagg taaaaagcaa ttcttgaagg cactctggtg tcaaatcaga
     2401 caacttttta tcaccaatcc atcgaacaat aatttttaat tgttcctctc gcttatcata
     2461 ggttatttcc ttttgttcat ttaacgaacg gtaatattgg aaccattgct cacctacaac
     2521 actaaacttg tcattgcttg caacaatttt tttcttaagc ctttgttgtt tctccatttc
     2581 cagataagcg agttgcgcct cacgttttga attaaagcca cgtcttgttg ttcgatatgc
     2641 ttgaaagtac catgtgatcc taccagtaga actgatttgc ttcttgaatc gatctgtttt
     2701 ttccatttat tgattcctcc tattttgaag gaacccaaca agcagaaacc ctttggaaat
     2761 ctttctatct atgtcatcat tgtaccgcat cttagaaaga aaatgtaact tataaagatc
     2821 gaagtagtcg caatttttct cgatagtcat tcgaatcact ctttctcatc cattctaaaa
     2881 catcatcacg aaaatagtgt cctcgaatcc cgtaccaaca gggaggaaac tcaccaagtt
     2941 ttactaaacg gttcagtgta ctatcactta tctgaaatag tcgctttaaa tcagtatttg
     3001 ttaataccag aggtaaatga ctgactgcaa gcaatttttc cgtgtaatct tccagttttt
     3061 tttgtaaaat tgaatagaac tctatttcca gagaattaac atttgtttta acttccaact
     3121 ccatcaccct tctctctcaa aatcaaaacg accaccacgg taccccttaa aattgtaaaa
     3181 aaacactcca gtactccatc aaaacggact agaaaagagg aatttttaat atgaaacaag
     3241 gaattgcaga cataaaaata attaaagaaa ttcttgaaaa atctacggct aatgcaatag
     3301 cattcggaac aggaatcaac ttgagtacag taaaaaaact taaaagtgga gagagagctg
     3361 aagaaaaatt aaatcttgcc gatgctatta aaatcacaga atttggcatg aaaaatatgc
     3421 caaccaaaat cgaaatatgg aaatagtagt ttttctgatc tatcagctgt tttgccaaag
     3481 cacataggaa tctcacctcc ccccagtaat ggcgggccga tttggttacg gaagtatcat
     3541 tatcgtagtc gcgattctca tattaaaatt tgtcgcttaa aagctaacct tgtcatggcg
     3601 taactagaga atcaaaatct acatgtactg atagatttgc tattcatttg tcaaagagcg
     3661 ctaggctatt ttcagcctat ggaaatcctt tattttgacc cgataaaaaa cttccataga
     3721 atgaaaagga aagggaaaaa atactttaac gagttgtatc aaattcaagt atcttctcaa
     3781 tcaattttgt ttccagttgt ctacgcatat attcatctac atacataacc attccttttt
     3841 cttcttcata aactggtttc atggctaacc gtgaaatata attttgatat tttgacagaa
     3901 cgatggacat ggcaattgaa tcaccagaag ctgcggcttt gattgtcgtt agtggtatga
     3961 atggtatata tcgtttattt tgcttcatat ttgacaccca aatactttcc tagctcttcc
     4021 aaagccattt gtcgttggta ccaaacactg ccgagacttt tcccaataat atcgccaatt
     4081 tcacgatcat taagaccgat gaagaaggac ataaaaatga tttcttgtct ttgactaggt
     4141 aatgctgcaa tcgcatttgc caactcctca ttggaaataa agattttcat accaaggaca
     4201 ataaaagtac cactactatt caaatttggt tccaaataat agaactctgt acctaaccct
     4261 ttttgttcca atatttccat tgatatttgc cgttggcgaa atctagcgta cttcttttga
     4321 atatttaacg cctcattgca gactactttc ttacaaaaac tgtcaaacgt atgttgaatg
     4381 tgggtttcct ctgagtcgcc cataatattc tccccctcaa aaaattcatt caactcgttt
     4441 tacttctatc cctttccatt attactacaa tctagga
//
LOCUS       DAFENC010000104         4432 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.110, whole genome shotgun sequence.
ACCESSION   DAFENC010000104
VERSION     DAFENC010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4432
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.110"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(543..2048)
                     /locus_tag="LP493_002826"
     CDS             complement(543..2048)
                     /locus_tag="LP493_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL2134920.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="LP493_002827"
     CDS             complement(2045..2731)
                     /locus_tag="LP493_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2134921.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="LP493_002828"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="LP493_002828"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HBL2134922.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1239 a          919 c          729 g         1545 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa aggaatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgacttggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat at
//
LOCUS       DAFENC010000105         4172 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.111, whole genome shotgun sequence.
ACCESSION   DAFENC010000105
VERSION     DAFENC010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4172)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4172)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4172
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.111"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            463..642
                     /locus_tag="LP493_002829"
     CDS             463..642
                     /locus_tag="LP493_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134923.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
     gene            967..1230
                     /locus_tag="LP493_002830"
     CDS             967..1230
                     /locus_tag="LP493_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HBL2134924.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            1224..1574
                     /locus_tag="LP493_002831"
     CDS             1224..1574
                     /locus_tag="LP493_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBL2134925.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(1598..2211)
                     /locus_tag="LP493_002832"
                     /pseudo
     CDS             complement(1598..2211)
                     /locus_tag="LP493_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            2525..2947
                     /locus_tag="LP493_002833"
     CDS             2525..2947
                     /locus_tag="LP493_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134926.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            2957..3160
                     /locus_tag="LP493_002834"
     CDS             2957..3160
                     /locus_tag="LP493_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134927.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            3371..3955
                     /locus_tag="LP493_002835"
     CDS             3371..3955
                     /locus_tag="LP493_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBL2134928.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT         1438 a          624 c          760 g         1350 t
ORIGIN      
        1 acgacgatac agaagaaatc caaaatgaac ttgaccgtaa acgaatgcca tatcaacgat
       61 ttgaaaggaa aaaaaggcaa taatcattta taccgaaaag tgagaatgtg tgaaataaga
      121 acaaaaacct tgaaattaag ggaatggttc ttatttcgca ccaatcgctc caaccgcccc
      181 cgccgcttag gtggtgcgaa ataagcgggc aaagcccgat aacctaagag aaagaaggag
      241 atccatatga ataaaatcat tcctctgttg ttcgtactgt gtattggcga gatacttatg
      301 cgtcatggtg cagctgtaca tttaaacttc gtagtattct taggaatact agtattttgt
      361 ttgatttttt ggcgctttgt gttagccctt gtgagtctac tattcaagtt gattgcagcc
      421 atatttttca tagggttatt tcgatgaaag gagagagtac taatgccaat tgcaatagga
      481 aataaacggt tacccgtgac attagatgaa aagagacaaa aagaattgca gcaactaaag
      541 cagaagtacg gaaaaagtga atctaagatt atgtgtattg cgttagatct attgatcgcg
      601 caagaaaaag caggatttga tataccagca ctaaaaaagt gacgtcactt ttcatttgaa
      661 gaaacaaaag tgatagcact taattgttcc tactatttag aatattttct atgtcctttt
      721 tattccattt tgtatcaata actatgaaat ctttaaagta tccagatcaa tttttttctt
      781 acctgattct aaagattttg ttttcttaaa catattatga tttcctttcg actattttca
      841 tataaatgtt aacatagttt atggattcat ggaatgttaa tctaatttaa tagaaaagga
      901 taattaagta tatacgtttt ttcttatgta tgttatacta tgtatataca gaaagaggtg
      961 tctactatgg aaatgttacc tataaaaaaa tggggaaata gtaatggcct tagattgcca
     1021 aagtatatta tggaatatct tggaattcat acagaagaca aagtgaagat aatacaagaa
     1081 gaagtaaacg gtcagaagcg gctaattatc gaagcggcta atatagaaaa tgaattaaca
     1141 attgaacagt tatttgaaaa ttacactgat gaaagaaatc atgtgacgat tcaaaattta
     1201 ggtgaagcag taggtaatga aaaatggtga gaaaacctag acaaggcgat attctattat
     1261 tgaatacagc acctcgatct ggacacgaac agacaggtaa aagaccttat attgttttaa
     1321 gtcatgatat tattgcggat tatagtaacg ttgttacagt tgctccaatt tctagtacaa
     1381 ctagaaacta tccgctatat gtaaatataa actcagaata tgaaatgaag acaacaggaa
     1441 aagtattatt agatcaacta acgacaattg attatgaagc cagagagtgt atttttttgg
     1501 aaaaagcgca tgatagttta gttgaggagt tattgatgaa agttagaaca gtttttcaaa
     1561 aagtaagcaa ataaaataga aacagcagca tgatcaacta ttcgtgattg accatgctgt
     1621 ctttttttat tctatatacg gtttgtctcg taacattgta gtcttttgca atcttagcga
     1681 tcgcaacacc ttttttagat cctcaacgat gtttttataa acaagacgac gttggggatc
     1741 ttttgcattg gcactgtata gcttaggacg tcctttataa acaccgttcg cttttgcaat
     1801 cttaatgcct tgtgcctgac gtcgtttaga ttcggtacgt tcttgttcag cgatcatggc
     1861 caaaatttga atgatcaaat ctttaatgaa tttatccagg agaggattgc caattgcttc
     1921 ggccatgatc ggtagacttg tgatgatcag ctgcacattt ttcttcttca agtaattgac
     1981 tgaagcgatg atctcgtcgt aatttcttcc aagtcgatca atagcttcca caataaaaat
     2041 atcttgatct cggacgaaat ccagtgcttc ttgaaaaaca ggtcgatgag taatcgttgc
     2101 gccagattgt ttctcaatga aaattctctc tgcaccgaat tttttcattt cttcaatctg
     2161 ccgttgttca ttttgatcga tggatgagac acgtatgtat gcaactctca aaatttttac
     2221 ctactttctg caactattta aaaaacaccc taatcataca cgagaaaacc agatttttca
     2281 atgtcgcggt cgtgtctagt tagggtatac cttatataga caaaaactaa tgatggagga
     2341 aatagtatgt gtcacttttc tttttaaatg gcaatatttt ttgtaaataa atgtcaatca
     2401 agaaaattta aacgattatg acattaaaaa tatattttat gaattttcta gtatataact
     2461 tgatttatct gttaagattt attaagaaaa cgttttctta tttttgattt cgaggtgata
     2521 gacaatgaaa aataagttta ttttatcttt aggtatttta actattggaa ttagtgtaac
     2581 tggaactaca attcctacat ttgctgatag tacaaatgaa ccaactactg tagtagataa
     2641 taaccaagaa ttaactcctt tagataggaa cggaatagcc attggtaacc caactaacga
     2701 cttaactgtt actgaaaatt atttaatagt ttctccatta cttgctcgag cagcttctaa
     2761 aacgatacga gtgacaggaa cgatgatttt tgataaagtt ggttggcctt ctagacctcc
     2821 tcaatcacgg aattggaaag aaaaaagaaa tggttattgg tactatggaa aattgtattt
     2881 acaaagttat aaatcagctg gaaacaattg gattgcgact tattcaggaa ccttaactag
     2941 aaagtaggga ttttttatgc cagaatttgt gaacacacca aatttttatc aagatagcga
     3001 tattctaagt aaaattaatt taccgaaaga agaatcagct ttacaagttc agcgaacttt
     3061 acaggagaca caaaaaattc aaaaatcaat ttctaatcta gaagattctg aagaaaaaag
     3121 aaaaaaaaga gaccaaaaaa catatcaaaa agaaaaataa tgattttaaa aaaagagtgt
     3181 ctagtcgaca ttcttttttt ctaattgaaa gtgttcataa aatcacccat ttctggacac
     3241 tttctttttt tgctttattt ttcaaaaaaa caattcattt catgttcata aacccataac
     3301 aatatctatg ttcagttaaa ctatatggat aaagttatgt tacaataaaa ttaatgaagg
     3361 agtgattttt ttgaaaatag gatacgcccg ggtatctact ggtttacaaa atttggattt
     3421 acaagaagac agcctaaata aatttggttg tgaaaaaatt tttactgatc atatgagtgg
     3481 ggcaaaaagt aatcgaccag gattagaaat ggccattgat tttgttcgct ctggcgatac
     3541 acttgtcgtt tggcgcttag atcgtttagg tagaaatatg gaagatttga tttcaatcgt
     3601 caatcgactg aatgagcgtg gtgtgagttt tcatagtatt caagaaaata ttacgatgga
     3661 caaatcaagt tctacaggac agctcatgtt tcatttgttt gcggcatttg cagaatttga
     3721 gcgtaatttg atcctggaac gatccgcagc aggacgagca gctgctcgtg caagaggacg
     3781 gtttggtggt cgtcctgaaa aattgtctga acaagatttg gaattactga agactttagt
     3841 ggatagcggt acacctatta agactattgc ggaacggtgg aacgtctcaa gaaccaccat
     3901 ttatcgttat ttggcaaaaa tggaggagaa aaatggaaag acaaattctc attagttttt
     3961 gtcatttaat gctgaaaatt tttgccattt atctagaaaa gtgacaatag tatgagaatt
     4021 ttttgtaagt gtctactgat aacttattct caaatgttgt aaggatttta ttcatttgtt
     4081 aatattaaag aacggaactc caaaaaagtc cgtactctaa tttgcagtct ctcactcttt
     4141 tagagtgaga gtttttatta gattttcaaa tt
//
LOCUS       DAFENC010000106         4143 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.112, whole genome shotgun sequence.
ACCESSION   DAFENC010000106
VERSION     DAFENC010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4143
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.112"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..97
                     /locus_tag="LP493_002836"
     CDS             <1..97
                     /locus_tag="LP493_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL2134929.1"
                     /translation="RNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
     gene            complement(350..499)
                     /locus_tag="LP493_002837"
     CDS             complement(350..499)
                     /locus_tag="LP493_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134930.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            961..1173
                     /locus_tag="LP493_002838"
     CDS             961..1173
                     /locus_tag="LP493_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134931.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            complement(1451..3250)
                     /locus_tag="LP493_002839"
     CDS             complement(1451..3250)
                     /locus_tag="LP493_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBL2134932.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(3374..3970)
                     /locus_tag="LP493_002840"
     CDS             complement(3374..3970)
                     /locus_tag="LP493_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBL2134933.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT         1487 a          725 c          706 g         1225 t
ORIGIN      
        1 acgaaataat attcctagaa aatcactgga ttatcgaaca cctttggaag tatttttgag
       61 ttacgtaagt attgatgatc tgtctaactt aatttgacaa ttaagattat attaaatatt
      121 atacagataa taacggaata ttatcatcga aacagctaac aaaattgtca taaaaaacga
      181 gatggttgat attagaactt gtgtttttgt ttaggtctag agataaagag agacaatttc
      241 caaatatatg taatgaatac aaaaagacgt ttgtcgcgga ttaccgttac aaacgtcttt
      301 tattgatttt ccgagatctc atcagtcgcc atttggaatg gttcactcct tatctagatt
      361 cgtttaatgc tcggactgct tgttcgattg taataccaaa cgcaacgtta ttttcgtttt
      421 gtgcatcaat cgccataaaa cggttagaag ttgtatcaaa agctacgcgg tattgcatat
      481 ttgtttttgt aaacgtcata aaattcatct cctttgtaat gtaatttagt tcttgaaagt
      541 ttcctttaaa ctttcgaact tataccaagt ttagcatcgt acgttttttg atgcaattaa
      601 aaagcattta tcattttcct tatttatttt ttcttaaatg gtttagctat tttcttttaa
      661 tccgataagt agcccaatca tcaaggttac aaatactatt gcttgaatat aaatcatatg
      721 ctcacctctt tataaataac ttagcaatat aaagaaaaaa acgcacgaac aacataggaa
      781 tataaacaaa cgtttttgtc acaacgtcta agatcgtgtt aaaaaatagt tatctaaaaa
      841 gcagaaagat actcaaaata aaaaataaaa aaatggataa aaacgttttc aaatacaagg
      901 taatttgtta ttataaaata aagaaaaaac aaaataaaaa taaagaaaag agggaatgaa
      961 atggtaaaag cagaagtagg aagatcttat atatgcaaac cgatcggagt atctcatgaa
     1021 ctaatcggct gtattgaacg tacatatatc aacacggctg tcgtgtatgt tgaaagttat
     1081 gaccaacgag actatcaact tatcaatgaa agcaagtatc gcatgctcgt aaaattctgt
     1141 gatattagcg cacctgctga attggtttct taaacagtat ttttgagaat tcgcaagaac
     1201 tcccttataa tataaataaa gacagaaggg agcgagaaga tatgccaaaa agaaaaagtt
     1261 cagggaaaat gggaattatt cttgcagtga tctctgcaat tcctgctatt ttagctattg
     1321 ttcgtgcgat gaaggaatca agagaaagtt aagcacacat tatgagcgtc aaacaaaaaa
     1381 cgcatatacc tgcggtggca ggttatgcgt tttttgttgt ataaagactt ttttcattaa
     1441 cgatttttga ttagccgact cccaaaacaa aatttagcag tttatctgaa taagtgattt
     1501 cttcatctgt ttgtttcaca ctttcattta gtagtcccat ctcatcggtt atgataccat
     1561 ccacaccata aaacatcatg cgactcatag catctgaatc gttgattgtc catacatata
     1621 cttcttttcc gtcttggtgg gcagaattaa tgaagttacg gttgatcgta ctatattcca
     1681 ttgtcagaaa atcagcaggc gtcacagggg gcccaacaat attgaaaggt aagatgtagc
     1741 ccacataaaa gtttggttct gcttctttta aatctgaaac ggtttggtac gtcaaacttt
     1801 gcaaaatatg atggttctct aagataactt tgcggtattt atggacaaat cgttcgacaa
     1861 ggtcatccga atctttttta gaggtcttga tctcaataag taatttttgg tttagcttat
     1921 gtgctttttc caaataagaa tcaaaagaac aaacaggggc ttgcactccg ttttcagtaa
     1981 ctgtaagatt tgtcaattct ttcaatgtaa gatcctgtgg tgttccattt acccctgtta
     2041 agtgacgaag atttgcatca tgcatcacta cgaaatgacc atcttttgtt tcctgaacat
     2101 ccatctctac ataatcagga tgatagtctc tgcttgtttt ttcaagtgct tctaaagtat
     2161 tttgcgcccc attttgggta ctcacacctc tgtgagagac agtcactggt tttgtctgaa
     2221 cagctgaagt cagataatcc atattgtaaa gacagacgcc aataccgaaa aaaactgcaa
     2281 aaagagtcaa accagtgttt ttcagcgcag agaaacgcaa gttgggggct tgtgggataa
     2341 accacttagg gatctcaggc aagaagcctt cgtcatccat gaaatcaaca atgatataaa
     2401 aaatccctac ggtagacatc acgatattga ataataaaat cccttgtaaa agcgtcatag
     2461 caaacacagc gctgatcaat gcatagtctg ggaaaaattg ttcaaccata ctttgtgcca
     2521 aaataacaac gatatatcct aaagaagaaa ggagtaaaat cgtaccgcca atcacaataa
     2581 attggcccgt gatggccaaa agacgcgatt tggtcaatga ccagctttcc cgaatggctg
     2641 ctcgaaaagg acgatctcgt agaatcattt ccggtaaagc aaaaatcagt cgaatcccaa
     2701 tatagccaag gaaaatataa acgagtaaaa aggaactgac gatgatccaa cgattagcaa
     2761 aaataaaatc cataatgaaa gcggggattt ttatttttga cagtagatca gaattaaaac
     2821 ttaatccgct gatcggtaga atcaataaaa aataagcaag gaaaaacaaa aaagtaatgg
     2881 gtctcacttt cttcagctga agtatcgtca agtgtaagag ttgcttcaaa gagattggtt
     2941 ctttcttttt aataaaaaaa acactcatca aaagaaaagt aaattcgaaa taaactaaca
     3001 gtaaaatcgt catcaaaact acgattaacg agagtagaac cccaggatgt tgagaaaaaa
     3061 ttgaaggaat attgtcataa gacaaatagt caattgcccc tcggtgtaaa ataaaacggg
     3121 tcgtactgct caataagggt aaacaaataa ataaaataaa gccatgcatc agcaagacat
     3181 cacggaaata agcttgtgtt ccttttaaaa agtcccaagc attacctaag ctacgtttca
     3241 aataattcat cctatcacct gctcttcaca ttgtagcgca aatctaatga aaaaggaaag
     3301 ggtgcagtgt gttttgcaga ccctttccca gatttaacat tgtcaatcaa tgactaattt
     3361 tacaaaataa atattatcca agaagaccac ttagatattg acctccataa atcaaggcca
     3421 tactatataa gaaaatcgac agtggtttag caatcaaaat gattagtgta tatcgtttca
     3481 ctgacatgtt tgtcaatcca gccatcaaac ataacgcatc gtcaggagca actggaagaa
     3541 aaatagctag agcaaacagc ttctcaaaac ggttttgatt atccagccag ccaatatatt
     3601 tgttatatgt cttatcgcta atcatggaaa gtatgaatgg ctttccataa cgacgcccta
     3661 gcagaaaaat gataatcgaa ccaatgcaga ttccaatata gttatagata aatccagcat
     3721 aagggccaaa tatcaggaca ccagctgcag tactgatccc tccaggaatg attggaataa
     3781 ctacttgcag gatttggatg aagacaaaaa taatcggtcc taaaatgatg gaatcaccta
     3841 ctaatcctct taacgcattc aaatctttga aaacacctaa attaataaaa taaatcgtca
     3901 gcgcgattga taggcctaat ccgataatgg atatgaaatt tatcagtttt cgagaggcag
     3961 caatattcat tattcatcaa ctccttagag gttctttgtt aactatactt tactagaaaa
     4021 gcaactaact gcgccatttt ttgatatgac agaaaacaaa caattttgta agttcatcat
     4081 aagtataaaa gattgatctc aaaaaaacat ccaactaaag acttatttaa taacttgttt
     4141 ttt
//
LOCUS       DAFENC010000107         4063 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.113, whole genome shotgun sequence.
ACCESSION   DAFENC010000107
VERSION     DAFENC010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4063
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.113"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            82..1431
                     /locus_tag="LP493_002841"
     CDS             82..1431
                     /locus_tag="LP493_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2134934.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(1559..2149)
                     /locus_tag="LP493_002842"
     CDS             complement(1559..2149)
                     /locus_tag="LP493_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBL2134935.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            2296..3648
                     /gene="brnQ"
                     /locus_tag="LP493_002843"
     CDS             2296..3648
                     /gene="brnQ"
                     /locus_tag="LP493_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBL2134936.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         1169 a          744 c          789 g         1361 t
ORIGIN      
        1 ttttggaatc ttagttgtgt ttttcagaaa actctcttaa tatggaagta attaaacttt
       61 tttagttagg atgatttaaa aatgaatgaa gagcaagaac tgcagcgtgg actgaaaaat
      121 agacatgtcc aactgatttc tattggcgga gcgattggaa cggggttgtt tttaggttcc
      181 ggaaagtcta tccagctagc tggcccttcg atattgctcg cctatcttat tactggatgc
      241 atctgttttt tcattatgcg tgcgttaggc gaacttctgt tatcaaacac caataaccat
      301 tcttttctgg attttgttgc agaatatctt ggcaaaaaag cggctttcat cactggctgg
      361 acgtattggt tctgctgggt atcgattgca atggccgatt taacagccat cggaatgtat
      421 gtacgctact gggcgcctgg tgttcctcag tggcttcctg aactgattgc attaggtctt
      481 cttctttgct tgaatatggt ggctgtctca ttgtttggtg agttagagtt ttggtttgca
      541 ttgatcaaag ttgtagcgat cattgccttt atcctcgtag gagcttatat gatcctcacc
      601 cactatacga cagatattgg cacagccagt atcacgaatc tatggtctca tggcggattc
      661 tttccaactg gtgcaaaagg atttatctta gctttccaaa tggtaacctt tgcttttgct
      721 gggatagaat tagttggatt agtcgctgga gaaacagaaa atcctgaaaa agtgttgccg
      781 gaagctatca ataatattcc tatcaggatc atcttatttt acttaggatc tctttttgtc
      841 attatggcaa tctatccatg gaacagcttg aatccagata acagtccatt tgtagaagta
      901 ttttcggaaa ttgggatcac gattgctgct tccttgatca atttagtcgt attaagtgca
      961 gcagcttctg cctgcaacag tgcaatatat agtacaggac gtatgcttcg ttctttagcg
     1021 caagaaggca gtgcccctaa aaaattcaaa aagttaacaa cacatcatgt gccagggaat
     1081 gctttgacat tttctactat cgtcattttc atttctgtta tcttgaatta cgtgatgcct
     1141 agtgaagtat tcacactagt aagcagtatt gccactactt gtttcttgtt tatctggagt
     1201 atgcttgtct acacgcacat gaaatatcgt aaaagtatcc tcggcaaaaa agctcattca
     1261 tttaaaatgc cgttgtaccc atttagtaat tatctggtat ttctttacat ggcctttgtg
     1321 tgtgtcgtct tgttcctagg aaaagatacg agaatcgctt tattactaac acctgtgtgg
     1381 ttcttgcttc tattactaat ctatcatatg aaatatgaac gtaagaagta agaaagtagt
     1441 tgtgacagaa gtggtcagct tcgagaaata agaaggaatt tacgaaaatt gcttcttaaa
     1501 tttttgtgaa atttcggctt atttcttgga gataaaagct tctgtcccag cctcttttct
     1561 atttccccgg aaacaaccgc tgataatagg catctgcttt tttataggaa aaaatccaaa
     1621 taccagatac aaaaaaacgt ccgaataacc cgatcaacgg tacaaaaaag acaccggcaa
     1681 tcaagcataa gttaatcatc atggagataa gacttcgacg gtcctttgac aaaactctca
     1741 cgacatggga atctggttta tttgctttca tgatttgcct catcaagata ccaaaagaaa
     1801 aactccacat cgtgtatact aagacataag ccatctcagg ccaaaaagct tcagggttac
     1861 gcccgaccca actagtaaca gaaggacata aagtcagcca aaagagcaaa aagatattcg
     1921 accagaccac tcggtaatta attcgttctg ccatctgaaa tatacgatga tggttcaccc
     1981 agatcaccgc aacaaatata aagctgatgg tataagctaa taatgtattt cggatgaccc
     2041 ataaagaatg aaagctagat gtattaggga tcttgatctc taatacaaga actctcaaaa
     2101 caatggctac cactccatca gtaaatgctt ctaatctcga ctttgtcacg atgattcctc
     2161 ctcagatgat tcagcgcttt tattttatca cttacgttat taaataacca tcgttttata
     2221 tagggaattt tctgaaaatt gttgcatatt tttcgaaatt ttgttacttt taaaaaaacc
     2281 gtaaaggagt tatgtatgac aaaaaaatta tcatttaaag actatctttt tataggctcc
     2341 atgcttttcg gtctattttt tggtgctgga aatcttatct ttcccgttca tttgggtcaa
     2401 gaagcaggcg ctgctacctt ttgggcgaat ctaggtttct tggttaccgg tatcggtctt
     2461 cccttcttag gggtgattgc cattggtgta tcgaaaagct caggtgtata tgaattagca
     2521 aaacggataa atcaaacata tgcgatggtt tttaccatct tgctttactt agttatcgga
     2581 ccgttttttg ctttacctcg ccttgcaacc acatctttcg agattggttt agcaccattt
     2641 atcgatccta gcagacagac gctatatcta gcaattttca gtattgtatt ttttgtgctg
     2701 gcttggtggt tttcaagaaa accgacaaag atattagatt atgttggaaa gttcctgaat
     2761 cctgcatttt tggttttatt aggtgctttg cttctccttg cttttttgaa tccactaggt
     2821 tctgtaaatc aagcgcctat tcagccaaat tatcaagagc atgctttttt cacagggttt
     2881 actcaaggat ataacacatt agatgcgctt gctgctttag catttgggat catcattgtc
     2941 acaacaatcc aaaacatggg tgtaacaaaa cctgctgaaa tcgctaaaga cacgatcaaa
     3001 tctggtgcga tcagcattat attgatggga atcatttata ctttgctcgc ttatttaggt
     3061 gctatgagct taggtagctt tgctctaagt gaaaatggcg ggatcacgct ggctcagatt
     3121 gctgatcatt atttaggtac ttatggcagt atcttattag catttatcgt tatattagct
     3181 tgcttgaaga ccggtattgg tttgattaca gcttttgcag aaacattcac agatttgttt
     3241 ccgcaaagaa attacgcatt ctttgttgca cttgctagta tccttccttg tttagcggca
     3301 aacgtaggct tgacgaatat cattcaattt tcgttgcctg ttttgatgtt catctatcca
     3361 ttagcaatga cactgatttt actagtgtta gttggtcctt tgtttaagca gcgtacggct
     3421 gtttatcgaa tgactactta ttttacattg attgcttcga tttttgatgg gttgaacgct
     3481 tgcccagaaa ctatcaaaca aacacctatt gttcaaaatc ttttatatgt tgcggaaagc
     3541 tacttgccgt ttttcaaatt ggggatgggg tggatcgtac cagcagttat cggttttgtt
     3601 atcggactga tttggagttt cgctaagaaa gaagaagtag cagattgata aaagaggttg
     3661 tgaaagagac gttcagcctt gagcaataaa aagtaatttt gaaaaatggc ttctcacatt
     3721 tttgcataaa tttgacttaa taccgagaaa ctgacttttg aacaccgttt attgagaggt
     3781 cgtgaaaaag ccgcttagtt tcaagtatta agaaatattt tgtgaaaatg gcttctcaca
     3841 tttttgcata aatttgactt aataccgaga aactggcttt tgaacaccgt ttattgagcg
     3901 tctataaact gacctgagta ttagagaaac aaaacggcaa agtagctcca tatactttgc
     3961 cgttttgttt tgaactaata ccgaagagaa gctgatcaaa caacatttct tttataatat
     4021 agattttaga catatatatg atataaaaat agttttcgca aaa
//
LOCUS       DAFENC010000108         3956 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.114, whole genome shotgun sequence.
ACCESSION   DAFENC010000108
VERSION     DAFENC010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3956
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.114"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..156
                     /locus_tag="LP493_002844"
     CDS             <1..156
                     /locus_tag="LP493_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBL2134937.1"
                     /translation="DKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPVDA
                     ISYGVRK"
     gene            175..1452
                     /locus_tag="LP493_002845"
     CDS             175..1452
                     /locus_tag="LP493_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2134938.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1462..2118
                     /locus_tag="LP493_002846"
     CDS             1462..2118
                     /locus_tag="LP493_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBL2134939.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2118..3494
                     /locus_tag="LP493_002847"
     CDS             2118..3494
                     /locus_tag="LP493_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBL2134940.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            3624..>3956
                     /locus_tag="LP493_002848"
     CDS             3624..>3956
                     /locus_tag="LP493_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBL2134941.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDI"
BASE COUNT         1594 a          425 c          694 g         1243 t
ORIGIN      
        1 gataaggata agtgtattaa ttgtggaaaa tgtaaaaaag tttgccaaat gaataaagat
       61 tcagttgaga attgcaatca tctggagtgt atcagatgtg gacgatgtaa aaatgcttgt
      121 ccagtggatg caattagtta tggagtaaga aaatagaaag gagtagttag gaaagtgata
      181 aaaaatgcta tagcatatat tacaagaaag aaaaatagaa ctttaataat ttttatcata
      241 ttaactatag ttctttcttg cttgtattct tgtttaacaa taatgaaatc aagcaatgaa
      301 atagaaaagg ctttatatga aagttctaat tcttcaatat caataacaaa aaaagatggt
      361 aaatatttta atgttaatca atttaaagat attgaaaaat taaaagaaat tgaagaaaaa
      421 ataattcaat atgatggatt agcaaaacta aaagatgcta aagtagttag cggagaacaa
      481 agaataaata gagaagattt atctgacgaa tttaagaatg ttgtttcact cgaagctaca
      541 aataatacta aaagaaatat tttatttagt agtggagtat ttacaattaa agaaggtaaa
      601 aatatagaag aaaatgataa gaattcaatt attgttcatg aagaatttgc taaacaaaac
      661 aatctaaaat taggtgatga agttgatctt gaattactag atattgaaaa aagtggaaaa
      721 ataaaaagtc ataaatttaa aattataggg atcttttctg gtaaaaaaca ggaaacatat
      781 acaggattat cttctgattt tagtgaaaat atggtgtttg tagattattc aacaagccaa
      841 gagatattaa acaattcaga aaataatgaa attgcaaata aaattttaat gtattctggt
      901 agtgcagaat ctacagactt agccttaaac aaattgaaag agcttaaaat tgatgagtca
      961 aagtattttg ttgaaaaaga ttctaatgcg tttgaagagt ctttagagtc agtgagtgga
     1021 ataaaatata taataaaagt aatgacttat tctattatgt tgggtgggat ggttgttctt
     1081 tcattaatct tgattctatg gttaagggaa agaatttatg aaataggtat attcttatct
     1141 attggaacat ctaagataca aattataatg caatttatat tcgagttaat attcatatcg
     1201 ataccaagta taatatcttc cttattttta ggaaatgtat tactaaaagt aattgtagat
     1261 ggattcatta actcagagga ttcaatgatt tccggtggaa gtttaataaa taatagtagt
     1321 tttatgtcaa atataacaac acttggacaa agttatttaa tattaataag tattattgtt
     1381 ttatcagttg tatttgcttc ttcattaatg ttaatcaaga agcctaaaga aatcttatca
     1441 aaaataagtt aggagaaaat aatggatata ttagaaataa agaatgtagc atatagttat
     1501 gcaaattcta aagaaaaagt tttgtcagga gtaaatcaaa aatttgaact tgggaagttt
     1561 tatgcgatag taggaaagtc aggaacagga aaatctacac ttctttcctt acttgctgga
     1621 cttgataaac ctcaaacagg aaaaatattg tttaagaatg aagatataca aaataaagga
     1681 tatagtaatc atagaaaaaa taatatatct ttagtatttc aaaactataa tttaatagat
     1741 tatttatcac caattgaaaa tattagatta gtaaataaat cagcagatga aagtatcttg
     1801 tttgaactag gtttagataa aaaacaaata aaaagaaatg ttatgaaatt atctggtgga
     1861 cagcaacaaa gagtagctat tgctagagca ttggtatcag atgctccaat aatactagct
     1921 gatgagccta ctggtaatct agacagtgtt actgctggag aaataattaa tatattaaag
     1981 acattagcta aagatagaaa taaatgtgta atagttgtaa cacatagtaa ggaagtagca
     2041 gattctgcgg atatcatttt agaactaagt ggtaaaaagt tgaaaaaagt aaataaaatg
     2101 aatttggagg ttgaataatg ataaaaaatg catttgctta tgtaactaga aaaagtttaa
     2161 aatcattaat tatcatatta gttattttat ctatgtcaac tttaagtctc attagtttat
     2221 ctattaaaga tgctacggac agagcttcaa aagaaacatt tgctaatata acaaatagtt
     2281 tttctatgga gataaataga caagtaaatc caggaacacc tagaggtggg ggaaatgtaa
     2341 aaggtgaaga tattaaaaag atatctcaaa cagatagtat agactcctat gtaaaaagaa
     2401 taaacagtgt tgcagattta gttgattatg atattattga aactcaagag actcttgcga
     2461 atcaatcacc tgaaagagca aagaatttta aaagaacagt tatgttaact ggggttaacg
     2521 actcaacaaa agaaacaaaa tttgtatcag aagcatataa attagtagaa ggaaagcatt
     2581 tagaaaatga agataaaaat aaaatcttaa tgcataaaga tttagctgaa aaaaataacc
     2641 ttaaagttgg agataagata aaaataaaat ctaatttatt tgatgctgat aatgagaaag
     2701 gtgcagatga aacagtagaa gtagaaatta aaggtctatt cgatgggcat aatagcggtg
     2761 gagtaagtgc agcacaagaa ctatacgaaa atacattaat cactgatatt catacagctg
     2821 ctaaagttta tggtaatacc gaagatacag ctgtatacca agatgcaaca ttctttgtaa
     2881 aaggtgataa gaatcttgat agtgtaataa aagatcttgg gaaattagat ataaattgga
     2941 gagaatataa tttgattaaa agttcatcaa attaccctgc attacaacaa tctatatcag
     3001 gtatttactc aatttcaaat aaattatttt ttggctcatt aatatttgca ggagttgtag
     3061 tttcattatt attattctta tggatgaatg ctagaaagaa agaaatagca gtattactat
     3121 cattaggtat atcaaaatta gaaatttttg gtcaattcct aattgagatg gtatttatat
     3181 caatccccgc attcgttggt tcctatttct tagctcaata tacagctgac aagcttggga
     3241 ataatatatt gaataaggtt actggtgata tagctaaaca aatagctaaa caatctgcat
     3301 ctagccaatt aggtggtggg gcagaagctg aaggatttaa caagacatta tcaagtttag
     3361 atatcaatgt attacctaaa ttcatgattt atgtagttat atttatgagt ttagtacttc
     3421 ttgtatcatt gattatttct tcattcaata tattaagaag gaatccaaaa gaattattaa
     3481 ttgacaataa ttaaaatttt cggtgctttt tagcaccaaa aatgagagtg taatataaac
     3541 cgtgtaagta accatcaatc ctaggcgggt ggttgcttca cggtttttat ttttctaaaa
     3601 taagatcaag aggtgattac acgatggcta gaaagaaaag aaatcctgat gctgagaagt
     3661 tagctgaatc cattttgaat acttatcaac ccgaatctgt agaggatatg caagatgttt
     3721 taaaagatgt gtttggtccc ttatttgaaa aaatgcttca aggagaattg aataaccatt
     3781 tagggtatga cgcccattct aaagagccaa agaaacatga caatcgacga aacggttatg
     3841 gcaataagac gcttaaaacg agctttggta aagtaaacat tgatgttccc agagaccggg
     3901 aggcttcttt tgaacctgag ttgattccta atagaaaacg agatgtctcc gacatc
//
LOCUS       DAFENC010000109         3935 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.115, whole genome shotgun sequence.
ACCESSION   DAFENC010000109
VERSION     DAFENC010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3935)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3935)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3935
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.115"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            201..773
                     /locus_tag="LP493_002849"
     CDS             201..773
                     /locus_tag="LP493_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBL2134942.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMIEPISLGFYEQNWYLIGFAG"
     gene            1071..1967
                     /locus_tag="LP493_002850"
     CDS             1071..1967
                     /locus_tag="LP493_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBL2134943.1"
                     /translation="MIQYYYTKKEWGVVMEKEKLKILEELRRILNNKNEAIIILNNYF
                     KGGVGKSKLSTMFAYLTDKLNLKVLMIDKDLQATLTKDLAKTFEVELPRVNFYEGLKN
                     GNLASSIIHLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIII
                     DTVPTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFV
                     PYLVDTDSATIKSNLEELYKEHKEDNLVFRNIIKRSNKVSTWSKNGITEHKGYDKKVL
                     SMYENVFFEMIERIIQLENEKE"
     gene            2066..2275
                     /locus_tag="LP493_002851"
     CDS             2066..2275
                     /locus_tag="LP493_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HBL2134944.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
     gene            2292..2564
                     /locus_tag="LP493_002852"
     CDS             2292..2564
                     /locus_tag="LP493_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBL2134945.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            2566..3429
                     /locus_tag="LP493_002853"
     CDS             2566..3429
                     /locus_tag="LP493_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBL2134946.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(3692..>3935)
                     /locus_tag="LP493_002854"
     CDS             complement(3692..>3935)
                     /locus_tag="LP493_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBL2134947.1"
                     /translation="PKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKN
                     QFHQAMKHAKVNNLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT         1467 a          603 c          738 g         1127 t
ORIGIN      
        1 aactgtccat actctgatgt tttatatctt ttctaaaagt tcgctagata gagttctata
       61 ttagagatgt aaagagtttt ggtgaagagg tttgtgagta tggcttttat aaccagggtg
      121 caatgagaag cactaacagc agctagctta agaacgcata ggatatactt tttatggaag
      181 tcacagagga ggaataaaat ttgaacagga ttaacagagt aacctctatt cttattcagc
      241 tgcaatcaaa aaaaataatt cctgccaaag aaattgcaca gcgatttaat ataagcttaa
      301 ggacagttta cagagatatc cggacacttg aagaagccgg aataccaatt ggatctgagg
      361 ccggaaaagg atattttctt gtagagggct tcctacttcc gccggtaatg tttacagcgg
      421 cggaagtggg tgcattgatt acagcaggga aatttttaaa ttgccatgga gatgaatcat
      481 ttataaagga ttttgattca gctatgtata aaatcaaatc tattttgaag catggtgaaa
      541 aaaactatgc acaggagttg gagaacagta ttaacgtgta cagcacatct ggacagaaaa
      601 atacattggc ggataacgtt attgcagcaa ttcagactgc aatctgcaat aaaagggtaa
      661 tatcaattca atatcctgca tcaggagggc aagaaccgga aagcagaatg atagagccta
      721 tatcactggg gttttatgaa cagaactggt acttaatcgg ttttgcaggc taagaaatga
      781 atataggaat tttcgtgtgg atcggattaa aagcatttgc atagaagaag agctctgtca
      841 aagccatgat ggctctttgg aacaaatatt aaaacaaatg ctttcatata aaaaactata
      901 tgccctacaa tgccgttgta aaaattgggg aaaagggata tattgatttt atatctttct
      961 caaaataaat ataaaagccc tttaaagagg gcttttatat attaatcaca aatcacttat
     1021 cacaaatcac aagtgattaa tcacaaatca cttgtgattt gtgattctta atgatacaat
     1081 attactatac aaaaaaagaa tggggcgtag ttatggagaa ggaaaaacta aaaatacttg
     1141 aagaattaag acgtatttta aacaataaaa atgaagcaat tattatcttg aataattact
     1201 ttaaaggtgg tgttggaaag tccaaattat cgactatgtt tgcttacttg acagacaaat
     1261 tgaatttaaa agttttaatg atcgataagg acttacaggc aacattgaca aaagacttag
     1321 caaaaacttt tgaggtagaa ttgccacgtg tcaattttta tgaaggcttg aaaaatggaa
     1381 acttggcttc ttctattatt catttgactg ataatttaga cttgatccct ggcacgtttg
     1441 atttgatgtt actgccaaaa ttaactcgct catggacgtt tgaaaatgaa agtagattgc
     1501 ttgctactct tttagcacct ttaaaaagtg actatgatct tattattatt gatactgtac
     1561 caacgccaag cgtttataca aataatgcaa tcgtggcgag tgattacgtt atgatccctt
     1621 tacaagcaga agaagaaagt acaaacaaca ttcaaaacta tatttcctat ttgattgatt
     1681 tgcaagaaca gtttaaccct ggactagata tgattggttt tgttccttat ttagttgata
     1741 cggacagcgc aacgataaaa tcaaacctgg aagaactgta caaagaacat aaagaggata
     1801 atttggtttt ccgaaatatt atcaagcgaa gtaataaagt aagtacttgg tctaaaaatg
     1861 gcattacaga acacaaaggc tatgacaaaa aagttttgtc tatgtatgag aacgtatttt
     1921 ttgaaatgat tgagcgaatc attcaattag aaaatgaaaa agaatagaat cacaaatcac
     1981 aagtgattaa tcacaaatca cttgtgattt gtgataggtg atgataaaat aaatagtaag
     2041 aagaaataga aagaagtgag cgatcgtggg aaatttaggc gcacagaaag caaaacgaaa
     2101 tgatacgcca atcagcgcaa aaaaagatat aatgggggat aagacggttc gtgttcgtgc
     2161 cgacttgcac catatcataa aaatcgaaac agcaaagaat ggcggaaacg taaaagaagt
     2221 tatggatcaa gccttagaag aatatatacg gaaatattta cctgacaaac tttaaaagga
     2281 gtgaaaatga aatggcagtt acgtatgaaa aaacatttga aattgaaatc attaatgagt
     2341 tatcggcaag tgtttataat cgggtattaa attatgtttt gaatcatgaa ctagatacta
     2401 aaaatactcg tttactagaa gtgaatcttt taaatcaatt agaagtggca caagaagttg
     2461 atttatttca acaaccattt gaagaattac aagctattca tgagtattgg cggtcaatga
     2521 atcaatattc aaaacaaatt ttgaataaag agaaagtggc ttaacatggc gaatattact
     2581 gacttcaccg aaaagcaatt tgaagatcgt ttagaaaaga atgttgaacg actaactaaa
     2641 aatagactag cggttgaatc gccaaccgct tttttacttg gtgggcaacc agggtcaggg
     2701 aaaaccagtt tgcgatcagc aatttttgaa gaaacacaag ggaatgttat tgtcattgat
     2761 aatgatacct ttaaacaaca gcacccaaat tttgacgaat tagtgaaact ctatgaaaaa
     2821 gacgtagtaa aacacgttac cccttattcg aatcgcatga cagaagcact tattagccgt
     2881 ttaagcgatc aaggctataa tttagtgatt gaaggaacag gacgaacaac agacgttccc
     2941 attcaaacag ccacaatgct tcaatctaaa ggttatgaaa caaaaatata cgtcatggca
     3001 gtaccgaaaa ttgaatcata cttaggaacg attgaacgat atgaaaccat gtatgcagat
     3061 gatccaatga cagctagggc aacaccaaaa caagcgcatg atattgttgt caaaaactta
     3121 ccgaccaatt tagaaaccct tcataaaacg ggcttattta gcgatataag gctttacaat
     3181 agagaaggag tgaaactcta ttcaagctta gaaacgcctt ccattagtcc gaaagagacc
     3241 ttagaaagag aattaaatcg taaagtatca gggaaagaaa ttcaaccgac tttggagaga
     3301 atagagcaaa aaatggttca aaatcaacac caagaaaccc ctgaatttaa agcaattcaa
     3361 caaaaaatgg aaagcttgca gctacctaca ccaccaatac ccaaaacacc taaacttcca
     3421 ggtatttaaa ccttaaaaaa ggaaaagagt agttaccaaa aaacggtaac tactcttttt
     3481 ttataaaaac atttcctcat gttggggtcc cgagcgccta cgaggaattt gtatcgataa
     3541 gaaatagatt taaaaatttc gctgtttttt tctaatttca ttttgaggtg aattaattgg
     3601 tagttattag aggtgcccta tacctaataa tttatctaca ttccctttag taacgtgtaa
     3661 ctttccaaat ttacaaaagc gactcataga attatttcct cccgttaaat aatagataac
     3721 tattaaaaat agacaatact tgctcataag taacggtact taaattgttt actttggcgt
     3781 gtttcattgc ttgatgaaac tgatttttag taaacagttg acgatattct cgattgaccc
     3841 attttgaaac aaagtacgta tatagcttcc aatatttatc tggaacatct gtggtatggc
     3901 gggtaagttt tattaagaca ctgtttactt ttggt
//
LOCUS       DAFENC010000110         3762 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.116, whole genome shotgun sequence.
ACCESSION   DAFENC010000110
VERSION     DAFENC010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3762
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.116"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..218)
                     /locus_tag="LP493_002855"
     CDS             complement(<1..218)
                     /locus_tag="LP493_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
                     /protein_id="HBL2134948.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYYQKLTDNPIGFGLLPEDDEGNE"
     gene            complement(837..1169)
                     /locus_tag="LP493_002856"
     CDS             complement(837..1169)
                     /locus_tag="LP493_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HBL2134949.1"
                     /translation="MSYTGILSLEDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYAGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            complement(2016..3056)
                     /locus_tag="LP493_002857"
     CDS             complement(2016..3056)
                     /locus_tag="LP493_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBL2134950.1"
                     /translation="MTDFNFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCSVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFIPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAETESGISIIFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNSE
                     SFPKTITKDWLE"
BASE COUNT         1232 a          662 c          496 g         1372 t
ORIGIN      
        1 cattcattac cttcatcatc ttcaggtagc aagccgaatc caattggatt atcagtcaat
       61 ttttgatagt ataaatcatc ctcgtctaat gctaaaacat ctaatccttt acaatttccg
      121 cctcttctaa acgtcacaaa tcctttgtaa tcccaacgtt ggaaagaaac cttaatagta
      181 tgtgtgccca atcgtatatt cggatcataa tttttcattt gtcattcctc cattacgtaa
      241 atttcatttt ctctatgttt tatatcaatt ttttcacttt attcaggact cgttcatatt
      301 ttatcgtttt tcgtttactt aaaaatacat aaaaaatatc gactcgttta tggcgtccga
      361 aacgagaaac cctagtagaa atcggtaaat gctcgattga tccaatgacc aacgtcctcg
      421 caagtatcta catgtactgc agcacacgac acaatttctt gtgcgtcctc cccattacga
      481 gaagacctac tccttattcc atgagtttgc gtcaaagcct agatccctta gtagctgctc
      541 atgattaatc taggcgctat tctaacttgt ctaacttcta aattccctct tgtttactct
      601 gtgcatatta tttacacaaa ttcatttcac cactatccaa acaagggcat ttactcgatt
      661 gaccaatttt ttacgttacc aatcgtaaaa acctaccccg tcaccccccg aaaggaattg
      721 ttgatagatc aagtctactc cttatttttc tagtaattct aagttctttt agaagtctcg
      781 acaatatttt caagcaagcg aaaaacgata aaatacaagt tatgagaatg atcaattcag
      841 ctgattaaac gccccatccc ttttgcggta caacgcaaga ctccattttt tcttcgacca
      901 atcagtacac cgttttggtc ataaacatgt ttgattgttg gatatagttc ttttaaaggg
      961 ataggatctt ttaaaattat ttgcttttgt ttaccagcgt aataaatcat ttcctctgag
     1021 actttgtctt tctggattat atatttctta cactgcacaa cggttttact ttggccagtt
     1081 gatagtttct tcgtgatttt ctctgtagcg gtacaccgtt taccgtagtg acaaatatct
     1141 tcgagactca aaattcctgt atatgacata aaataatcca cccacttact ttaaatattt
     1201 ttaataagtt tttcttgtta tttttcaaaa atagagaatt gattttcgtt catgacaaac
     1261 aaaaaagagg gaacgcatcc aaacatgcgt tccctctaat ttcagcgttc gtcatacggc
     1321 aaagagccac acggacattt ttataacatt atgcttaggc atagattcat cgtaatatca
     1381 cgtattttta accttaacac agccaaaaaa agtggtatca cttttgaata tctgttatac
     1441 taaatccgtt gcgggtaata ccgtaacact gaaaggtaaa cgcattaagg gattaaaggt
     1501 tgtcttaatg ccacctgtgg acgtcgacga aggttaccag ccttccgagt ctcacagggc
     1561 ctttcttttt tttgtatttt caattgtcca aatttatcgt ccaaaagtgc agaacgaaaa
     1621 ttaattcatc acaagcgtag cagacaatta aatttaaaac aactaaattt atacaaaaaa
     1681 atgtaagcga ataatattcg tattgcctga aaagaagtaa tatcaaggtt tttagctttt
     1741 ttaaaaaatg aaattacctc tcttcgcgta ttattataac taaaaaacag caacatgcaa
     1801 acgtttgttc tcttttttgt gttggaaatt aattattaac tattaacact tatgacgtaa
     1861 aaagctacgt ttgtgatttt tatcataata ttttaactca taaattctat taaaatagct
     1921 atttctttgt aacatttgta atataattag aataataaaa aatttttaat tttaatgcta
     1981 ctccatgaag caacaatcaa tttgtcagtg aaatttcact ctaaccagtc tttcgtaata
     2041 gtttttggga agctttcaga attcaaacgt ttttcacttg atactttagc agctattggt
     2101 ttttcgataa accaattttt tacatagaca aaaatcaggt tctggatatt ttcaactttt
     2161 tcggttttta atttttgata ggcttttaac agtgtcgtgt ataattcttg ttctgcattg
     2221 acataataac tatcgagttc ttcaaaaatt attgaaatac cactttctgt ttcggctttt
     2281 ttctttgcat tatgaatagt ctggacagtt ttttgagctt cactgtaact tgaagaaaat
     2341 gtttttatta aatttaatac tcgttcaggg ataaacgtag caatgctgtc gtttgtcata
     2401 attgtctcaa aattgtctaa caacaattga tcttgtaggc ggtctttttc agtgtctata
     2461 ttgtgtctat tagtgtctaa tatattatta ttaagttctg gtatgatttt cataccctct
     2521 gatttatcaa cgttttggca cggtatgatt ttcataccct cttgagcccc aagggattca
     2581 gcgtctgatt tttcgtcgag ggtgggtatg attttcatac cctctgattt atcaacgttt
     2641 tccctattct ctctatcaaa tttttcgagt aagtagatat cattttctga gacttttaat
     2701 tctgctagat atagtctatt aggattattt ttccctaact gtttgttaaa tcccatctgc
     2761 ttttgtaata ataaaccaaa ggattccaac tcttttttga ttgctatcgc tttttgtttt
     2821 tggcagttta atacgctaca tagttcattt gtcgtataag taaaataaac attaccttct
     2881 tcatcgattt gccgtttgct gattgcgatc tctaatcttg cttttaaaag catataggca
     2941 atcttagttg aatctttcat ttttttgtat tcgtcagaaa caataaagac ttttggaaat
     3001 tgataaaata attcgttgta aactctatcc gccttaaaaa aattaaaatc agtcattgta
     3061 gatcctctac tttcacgttg ttttatttat gtaaaattac ctactctttt cgaaaatagc
     3121 aaagataaat aaaaaatgca aacgcattaa aactgttttt taattaaata ctacctaaaa
     3181 tcagaaataa aatgaattat gtactacctt taaagtcatt aagaactact ttaaataaat
     3241 attatttata attaaatact accagaagaa cgtatgaata aaatttagtt ttaaaattaa
     3301 agataattaa gtactaccag tgtcaaaaca aaaaataaat taagaactac cttatgcata
     3361 taaaacatac taccattact agtaatatat actaccttat ttcagtagta tatattatat
     3421 tcttcttata agacaaggct ttaggctaga aaacaataga ttatatacta ctaaaaaata
     3481 caataagtac taccaatgtc agatatatat aataattatg tactaccatt aaaattaact
     3541 tatttaataa gatactactg tgttaatctg aaaaaaatta ctttaaagta gttacatact
     3601 acctgttaaa ttagatacta ccattaatac ttaaattaga tactacctat atttatatta
     3661 agtactaccg ttctaggaat aagataataa aaaaaaacta ccaaattgca attaaatact
     3721 acttaaaatg taaaaaataa gaactaccca aattaggtag tt
//
LOCUS       DAFENC010000111         3395 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.117, whole genome shotgun sequence.
ACCESSION   DAFENC010000111
VERSION     DAFENC010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3395
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.117"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..174
                     /locus_tag="LP493_002858"
     CDS             <1..174
                     /locus_tag="LP493_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBL2134951.1"
                     /translation="HRPIKRRNKFYQSLRTASSTIKGMETIRGIYKKNRRNGTLFGFS
                     VSTEIKVLMGITA"
     gene            complement(231..662)
                     /locus_tag="LP493_002859"
                     /pseudo
     CDS             complement(231..662)
                     /locus_tag="LP493_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297423.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1221..1538)
                     /locus_tag="LP493_002860"
     CDS             complement(1221..1538)
                     /locus_tag="LP493_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBL2134952.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            complement(1539..1793)
                     /locus_tag="LP493_002861"
     CDS             complement(1539..1793)
                     /locus_tag="LP493_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBL2134953.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDTIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            complement(2053..2271)
                     /locus_tag="LP493_002862"
                     /pseudo
     CDS             complement(2053..2271)
                     /locus_tag="LP493_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(2831..2917)
                     /locus_tag="LP493_002863"
                     /pseudo
     CDS             complement(2831..2917)
                     /locus_tag="LP493_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
BASE COUNT         1137 a          594 c          485 g         1179 t
ORIGIN      
        1 catcgaccta ttaaacgacg aaataaattt tatcaaagtc tccgtacagc ctcttccacg
       61 attaagggca tggagaccat tcgaggaata tataaaaaga accgaagaaa tggaacgctc
      121 ttcggctttt cggtgtctac tgaaatcaag gtattaatgg gaataacagc ctaagatatt
      181 tggagttcag agagggcgcg tttgattttc aaacttcgca acagaacctt catatttcct
      241 tgattacctg aggcaatgaa agacttatct acttgaatta gggtgaaatt ctcattcaaa
      301 tatggtagta aaattaatat atgtgaaaat cgaatcttga gatagctatt ccccttgaga
      361 tattcactga tacttctact caaatcattt aaatttttat aattatttgt acggaacgta
      421 tatatatcaa catcagtttt ctttacatga gaacttattc taaaatgaaa aagcctactc
      481 tcagaaagaa ttgaaaaata gatactttca gtagatactg aagattgaac aaaattaaac
      541 ttgtatcctt caggcatagc acttttaaca gtctgctgca ttaactcgga taatcttttg
      601 aaagtagtaa tatatttttt accagcaaac catacatatc ttttttcatt aagtatgttc
      661 actatctctc ctccattaat tatatttagc atcaaatagt tattgtacct atattttatc
      721 ccattccttt taaaacaaga atacgtacaa agtaaaatgt tgtaaatagt ctagcaggga
      781 tgtatatttt catgtaccaa cataatattt aagaagtttc ccatagatat attggacttc
      841 ctcttttaaa acacaaaaat aaatactacc ttatttaggt agtatttatt aaaagttacg
      901 tcaattttga ttaaaaatat actacttgaa cctctcatga gtaaagtcac gaaatttttg
      961 ggaatagagc gtacttgata tcttattttt tcactaatag cagtgtctct tattcaccaa
     1021 gcgatccccg tagttcctac ggttcttaat ttttctctag actaatgatt gtatctttag
     1081 accttcggcc ataacatgga gcaaaataaa aaggtactaa gtcttatata tcaatcttcg
     1141 agtaaccgac ggttaacaac catatcgagc ggcattaatc acccacctgt agaggatgag
     1201 cgacttttgc ctaattattg ttaaaagcct agtttcattt gtttagattg gaaaatacgt
     1261 cctacaagta tctctttttt ttcatggtcg atccgataaa ataaggcata gcttttgccg
     1321 atcacgatcc gatatgttgg gatatccatt ccatagattt cggaaacttc ctcatgcata
     1381 gttggaaaat ttttggttag ttctaaagcc ttctggatcg cacctacaaa tctttttatg
     1441 ctggctggag aaagagcaag ctcattttcc cattcttcta ttatcgtttc aaggctggtc
     1501 tggaaacttt tagaataaac tagcgtgtac tctttcatct attcactcca gccgtatttt
     1561 ccgaaagctt ttaccatttc aatttctgaa actgttaaac ctttctcaaa gtcttggaaa
     1621 ctttcttcaa tcaatttgcg atcgtgttct tttgctattt gagtagtatc taatatgaat
     1681 aagttgcctt cttgtttggc ttggatagtg tctccgcttt ttaatccaag agagcttgga
     1741 aggatcactc ccacgctatt gccgatcttt ctaaccttta gttcttttcc catgttatca
     1801 cacttctttt agtttttgat aaataaatta taacatgtta taacgacaat tgccaacggt
     1861 gtttcttaag ggattccact ccatattatt attggacaaa ataagccact tagaacgctg
     1921 aaaacatata caaacgatat caaaatacga gtgaactact caccatacac ttccgttaac
     1981 atccatttaa gtaggtattt ttattatata tagatttaac atatgtcggt cggttgattg
     2041 atatagctaa agttataact caaccgaagc cgattcatct acacgaataa agttgcgagt
     2101 gttctcggct aattcataaa aattgttatg tgttccatat agcaatactg gaataacttt
     2161 attttcttga atctcataag caactctata cacggtgacc gcatacttaa atccattaga
     2221 ccaattacct gataaacctc cagttttttg ctcttactta aatggatcaa tagcaatttc
     2281 atcacaaacc tatagaggat gagtgacttc tgcctaatta cgttaaaaaa tattgaaagt
     2341 aactctatgt agcaaaaaat atctagaatt tcatttcctc aaaactgatc gatattgtat
     2401 ctaaaaatat atactaccta aaataggtag tatatattaa aatatgtgct tttgttagaa
     2461 aaatcaatac ataaattatc atatctgtat atgtcattta ggtatttcag ttatgttata
     2521 atagttttgc tgtctgctac cccggcctaa tctggcaagg ggaggaggag atataatgaa
     2581 ataccttttt gattttgttt ttgcaatcaa gccatttgca gaggtaactg cacactacat
     2641 ctgcaagtgg cttgattgca aaattgccaa aaaagacagt aagcctacca gttaattcta
     2701 taatatagaa acgtaaaaaa aaccccatca gcctacacgc tgatggggtt tgatgatata
     2761 atgaaatacc tctttgttac tcataattat accataatta gtcacgaatg caaccaatag
     2821 aaaaaactac ttagaacggt agatcatcgc taataacaat gcattgtcca ccaaatggat
     2881 tttgtgaagc attaaataca ttgttattaa ttgtcgctgt ttttaactag gcctctcccc
     2941 ttctattata aaagaagata tatattattt cttaattacc tactacctta aaccaaaatt
     3001 taagtactac ctaatttaag tagtacttaa ataatctaaa aaatagttat cccaattgtt
     3061 atgcttttat aatacgatta tttgtaacaa aatgaatatt atataattaa acactaccat
     3121 atttaggtag tgtttaatta ttagcaaaac aaaaaatatt tattctattc tcttaacttc
     3181 aactaagtta tgctgcacac ctttatataa atcatatgca actcattagc tagacaaact
     3241 acaagcatgt agttttatct gttaattatg tactacctaa ataaagtagt ttataattaa
     3301 caggtatata tatttaaaaa tttaagatta atttttttat gacttgtaca aatttatctg
     3361 atattctctt attaagaact acctaatttg ggtag
//
LOCUS       DAFENC010000112         3367 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.118, whole genome shotgun sequence.
ACCESSION   DAFENC010000112
VERSION     DAFENC010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3367
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.118"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            3..587
                     /locus_tag="LP493_002864"
     CDS             3..587
                     /locus_tag="LP493_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL2134954.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            complement(664..1857)
                     /locus_tag="LP493_002865"
     CDS             complement(664..1857)
                     /locus_tag="LP493_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBL2134955.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            1921..2301
                     /locus_tag="LP493_002866"
     CDS             1921..2301
                     /locus_tag="LP493_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HBL2134956.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            2375..2737
                     /locus_tag="LP493_002867"
     CDS             2375..2737
                     /locus_tag="LP493_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134957.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
BASE COUNT         1150 a          554 c          638 g         1025 t
ORIGIN      
        1 atatggcatt cccacaacta gatttaaaaa gtgaaaaagg accaaaagct gttatcaaaa
       61 caaaccgtgg tgacattact gttcaattat tccctgaact agcaccgaag acggttcaaa
      121 atttcattga actttccaaa aaaggttatt atgatggcgt gatttttcac cgcgttattc
      181 ctgatttcat gatccaaggc ggcgatccaa ctggaacagg aatgggtggc gaaagtattt
      241 atggcgaaag ttttgaagat gaattcagtc gtgaactgtt caaccttcgc ggagctttat
      301 ctatggcaaa ttcaggtcca aacacaaacg gaagccaatt ctttattgta aataacacaa
      361 atgtgccagc taatatgctt ggacaactag aaggtgctgg attcccatca gaaatcattg
      421 aagcgtataa aggtggcgga actccttggc tagatttccg acatacagtc tttggacatg
      481 tactagaagg gatggacaca gtagatgaaa tcgcaaatgt acaacgtggt ccacaagacc
      541 gacctgtaca tgatgtagtg attgaaacaa ttgaaatttc agaatagttt ggtatggtac
      601 ggagtaatta tgaaaaagga cgaaacctag taaggtctcg tccttttatt ttgaataaat
      661 gatttaatcg attgtctcta aagcatactt gattcgatta agtccttcca gtaaagtttc
      721 ttctggacaa gcaatattca agcgcatatg cccatgaccg gaaggaccaa acgtgatgcc
      781 aggatttaat acgacttttc ctttccgaac aagagtgttc tccaattctt ggtcgtctga
      841 aatataggcg gtaaaatcta accacattaa gtaagttcct tcagggttca ttattctcac
      901 tttcggaaga tactgttcaa aaaactgatt aactgtttga acattttttt ctagataagg
      961 aatcagttgg cttaaccatt ctccacccgt ctcataagcc gcttgggttc caatcagtcc
     1021 aaaagtgttg atttcgtgct gttggttcat cactaaatgt ttttcaaaat cagctttcat
     1081 ctctggattt ttgataaata ccattgaatt tttgattgca gctagattga aagtcttggt
     1141 tgcggaagta aaagcaacta gtagatcatc taaattagga tcaatcgtta gcatggaagt
     1201 aaatgtatga tcgaataaag ttaaatcttg atggatctcg tcactaaaca gaatcacttg
     1261 atgttttaaa cacaattcgc ttaactgttt caattcttct ttgctccaaa cacgccctcc
     1321 aggattgtga ggattgcata aaatcattgc ttttacattg ttttcttcga tttttttctc
     1381 catgtcagac aagtccatga tgaaatgatt atttttttct agcaaagagc ttcgaacgat
     1441 gtgacgttga tttgtttcta taatagagga aaatggagga taaactgggt catgaatcaa
     1501 aatagaatcg cctggttttg taaaagtttg tactgctgca gctaaactgg ttaacacacc
     1561 acttgtaaaa acgatatttt ctttcgtcaa ctccacagca tggtgttggc gttcccaatg
     1621 aatgatagcc tgatatagtt tatcagacag agtggcataa ccaaagattc catgtttgat
     1681 gtattcacta aacgctttag ctaccccacc gggagacaag aagtccatat ctgctaccca
     1741 caaaggaagt aagtcatcca tttgatatgt ctcagcaatt gcgtcccatt ttacactttc
     1801 tgtatctttt cttgaaatct gtttatcaaa ttcgatcatc ttaagacctc cagtcatttt
     1861 cgtcgcttct ttttttgagc tatttacagt ataatgataa atgcgaagag agggaagtag
     1921 atgacttata aaattggaca aataattgaa ggaaaagtga cagggataca gccttatggc
     1981 gcattcgttt ctcttgataa cgagacgcaa ggacttattc atgtttcaga agtacaatcc
     2041 ggttatacga aaaatatcca ttcattgtta aaagtcggac agccagtaac agttcagatc
     2101 atcgacattg atgaatattc caaaaaaatc agtttatctt taagaacgtt agaaaaaaca
     2161 aatccagctg ttccatatcg cagaaaaagg tatttcacga ataaaaatcg taagatcgga
     2221 tttaccacta ttgcggagca gttacctatt tggatagaag aagcattatc tgaactagaa
     2281 cggaaagaaa ataagaaata aaaagtgtat tttttctgaa aatgtgctag aatttttatg
     2341 taagccatag aacaagttga tcgaggtgga aattttggca agcaaaagag ttgctggtac
     2401 aattatgttg catttggagg atggtactaa aaaatttttg gtccattcaa ttgatgacaa
     2461 gttggaattt gcgttagcgg aactttctga aggaaagact ggtttagcga atatacttaa
     2521 tttcttaaaa gaaatagttc atatcgatgt tagcaagatt agtttgatgg aattgacaaa
     2581 tacacatatt aaagaggaaa atgttccgtt gtttgtcttt gaaactgaac aaaagaatca
     2641 aagagaagaa ttaggcgaag gatatatttg ggaagaacca ggtcaaatgc gctctgttct
     2701 tggaacttac gaagtagagg gagtgccttt cttctaaaat acagattaag cgaacaaaga
     2761 agtttgaatt tttttcaaac ttcttttttt attgtttggt ccaaaaaata caatgaaatg
     2821 ttctgctaaa gatagttttt tagtgcattt tattttcaaa atatgttgaa aacggttgta
     2881 taacgaataa taataattga tcgaaaaatc atttcacaaa gtaatgctta atttatagtt
     2941 gaccaaggaa gaaatacatg ataaatttaa cagcgttgat tctgaagtgg atgttatatc
     3001 acatttctaa aaaatttaaa aaatagttat tgacatgtta ctaacgacat gataagataa
     3061 ctgagtcgtt aaaaaagaac cacttgcgaa gcttgattct atcgaaaaaa acttcaaaaa
     3121 agttcttgac aaataacaaa cgataagtta tgataaatga gttgctgaaa gatttcgaaa
     3181 aacgaaatcg aaaaaaactt ttaaaaaaga gttgacaatc gcttgtctct ctgatatgat
     3241 ataaaagttg ctacggcagc caaaaacgaa tcgggaaaca ctcccgatga agtagacctt
     3301 tgaaaactga acaaagtaag acaaaccaaa tgtgtagggc gtcttgattc aattcaagac
     3361 aacaaac
//
LOCUS       DAFENC010000113         3199 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.120, whole genome shotgun sequence.
ACCESSION   DAFENC010000113
VERSION     DAFENC010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3199
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.120"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            301..585
                     /locus_tag="LP493_002868"
     CDS             301..585
                     /locus_tag="LP493_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134958.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            588..1004
                     /locus_tag="LP493_002869"
     CDS             588..1004
                     /locus_tag="LP493_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134959.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            complement(1141..1860)
                     /locus_tag="LP493_002870"
     CDS             complement(1141..1860)
                     /locus_tag="LP493_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBL2134960.1"
                     /translation="MDEKTELTVKYQNELNLVPLKNFNAKQMDLFFALCARMKDRGLK
                     KVRFSFEELKELSDYKMTATKAFVGDLEKLYKDMLNLTYRTEDEDSIRYFVLFTGFEI
                     NKTKKFVEVSVNPDLEYIINGLTAEFSRFELSAFTSLRSTYAKTLFRLLMQYRSTGYY
                     VVRIEEFRSLMDIPEYYQMGNIDQKVLNPALRELKKYFNDLKVTKIKAKKGNKIAKLE
                     FTFSSLTSDLPKISLRNWLEE"
     gene            2513..2608
                     /locus_tag="LP493_002871"
     CDS             2513..2608
                     /locus_tag="LP493_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HBL2134961.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            complement(2910..3155)
                     /locus_tag="LP493_002872"
     CDS             complement(2910..3155)
                     /locus_tag="LP493_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134962.1"
                     /translation="MRLEKEKMEKFPYEYFQNLEKLEQAIQAIKFDLTDEKLLEYKNM
                     TPERKRSLEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
BASE COUNT         1065 a          597 c          499 g         1038 t
ORIGIN      
        1 aaaaaaaatg tcgtttgaaa aactaaataa atttttgatc gtgcattttt aaatttggtt
       61 atcgattaca cgtgcagcac tcccccccga attttaaaga gcataaggaa acgtgtaccc
      121 actttctaaa aaaagtgggt agataggctg tgcctatcac gtttctcaga aaaaaatttg
      181 atatcacttt ttcgccatcg tgggtagctt atgtatagca ttttggcaaa aaacagctat
      241 acaaatatag tatttgtatg gtatacataa attatacata attgcaaaag gagatttttt
      301 atggacattt tagttcggaa tattgatcca aagtttgttg caacaataga caaacgttgc
      361 caagaactca cgaataaaac aggagaaaaa tggagtcgaa ataaatatct aaaagtttta
      421 atcgaaagtg attttgaccg tcaacttacg acttacaaaa aagaccaatt cgatttattg
      481 ctcgataaat ttattgctat ccaaacagaa aatactcaaa tattaagcga gtatgtctac
      541 acaaataatc aaatcattga aatgcttatc ggaggaatga tataaccatg agaaaaactt
      601 ctgtccaaaa acatgttact ttgtacccta gtcatgttga cgttttagat tccatcatcg
      661 aaaaaaatcc agatatcaat aactactcgg aagccattcg ctttttatgt atgagttatg
      721 aacccgatac caacacgacc actaccagca atcaggcaaa actaaatgct atgggaaaag
      781 aaatttccat catgactgaa atcatcgcag aatttgctga tttatatcta aaagatacag
      841 gcgttcttat tggcacaaat tctaaagtat atcaagaagt gaaagaaaaa atcgaagcta
      901 aactaaatcc atcaaatcga aatcgaccaa agaatcatca aaaagaaacc agtcaaacag
      961 tcacttctag aaatttcgac ccaacaaatt ttctaaaacg ataaaaaaca gataggagtt
     1021 attcctatct gttttttatt tagaagcccc atacaatatg ctagaatgta ctagcaatct
     1081 tagtcggttg taagggactt gtctacttgc ttaatgtaag gggggcgagt tcttttttat
     1141 ttattcttct aaccagttac gcagagaaat ctttggcaaa tctgacgtta ggcttgaaaa
     1201 agtaaattct aatttggcga ttttattgcc cttttttgct tttatttttg tgactttaag
     1261 atcattgaag tattttttta gttctcgtaa tgcaggattt aatacttttt gatcaatgtt
     1321 acccatttga tagtattctg ggatatccat taagctccta aactcttcaa tacgaactac
     1381 ataataacca gtagaacggt actgcataag cagtcggaat agagtttttg catacgtaga
     1441 acgcaacgac gtgaaagcag ataattcaaa tctactaaat tcagctgtta aaccattaat
     1501 aatatattct aggtccggat taacactgac ttcaacaaac ttttttgttt tattgatttc
     1561 aaaaccagta aacaaaacaa agtagcgaat agaatcctca tcttcagtac ggtaagtaag
     1621 attaagcata tctttataga gcttttctaa atcaccgaca aaggcttttg tagcagtcat
     1681 cttataatca cttaactctt ttaattcctc gaaagaaaat ctaacttttt tcaaaccacg
     1741 atctttcata cgagcgcata atgcaaaaaa taaatccatc tgcttagcat tgaaattttt
     1801 cagcggtact aaattcaatt cattttgata tttgactgtt aattccgttt tttcatccat
     1861 tcctttcttc cccccttaca aataaataat aacctttaac aaccaactcg taaataggtt
     1921 ggttgttatt atacaaaagg atattagtac tcagataaaa agttgttagt actcagataa
     1981 aaagttgtta gtactcagat aaaaagttgt tagtactcag ataaaaagtt gttagtaccc
     2041 ttctgtatcc gttgggagag taaggctcaa ctgcccccta aaaagggttc taaaaaatct
     2101 ttaaaaaata aataaaataa acgcgcgcgc gcgagcaaaa tttcccgcca aaaaatcacc
     2161 cactttttaa aataaacagg ttcgcgcatg atattaaact gccaatctag ctccctatgg
     2221 tcgctgtaag aaggagtgat cgctacgctc tcacatttta cttgcagcag tcgcctttag
     2281 gctccttcgc caaaaataat tcattaggga ctcctttgtg gcgtcctgag agctcgtcta
     2341 agccgttcta agacaagatt cgataaaaac tatgtccttc gttctaaagc gccttacagg
     2401 cggtcagggc aagccctaac aaccccaagg caataaaaaa cttaggctta tttttgcttt
     2461 tttattgtat aattgattgt cgcctatccg acagtcttgc gactggaagg aggtgtgttt
     2521 cgtgttcact aactttattt gctcccttct tgttgggctt ttaagcgctt tgttcagtta
     2581 ctggttgaat aaccgaaaca agaagtaaaa cttaattaag gcgactcagc ccacaaaaaa
     2641 agccccagag aatccgacct ctctggggct ttcgtgtgtt tcgtgttcac ttatttgcaa
     2701 tcaaattata acagaaataa atatttattt caaaaatatc ctacaaaagt ctaaaatccg
     2761 taattatttc ttatatgcaa catttacaaa taaagtcgct ctgagagctc gtatttttcg
     2821 atttaagacg ttttatttag tttttggtgt atttcattgg tccaagctaa aaaactctta
     2881 gaagcgattt tagagccatt taaacccact taattatatt ctccatgaaa ttcgctccat
     2941 gcgtcaaaag ctgcgtctga aattccgccg tcttcgttca ctagttgcat taatttttcc
     3001 aacgatcgtt ttctttcggg tgtcatattt ttatattcca acaatttttc gtctgttaaa
     3061 tcgaacttga ttgcttgaat tgcttgctct aatttttcta agttttgaaa atattcgtaa
     3121 ggaaattttt ccattttttc tttctccagt ctcacaattt ttctagaaat aaaatcactt
     3181 ctttgccgtc tatactctc
//
LOCUS       DAFENC010000114         3019 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.121, whole genome shotgun sequence.
ACCESSION   DAFENC010000114
VERSION     DAFENC010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3019)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3019)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3019
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.121"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..306
                     /locus_tag="LP493_002873"
     CDS             <1..306
                     /locus_tag="LP493_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134963.1"
                     /translation="EVRIRNVDEKIVREIDRRCDELSNRTGNKWSRNDYLKLLVENDF
                     DRPLMEYKQDKFDQLLNQLIDKFSFVQSHNTKVLEEYICQNNQIIELLIEQSRGGEV"
     gene            308..730
                     /locus_tag="LP493_002874"
     CDS             308..730
                     /locus_tag="LP493_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134964.1"
                     /translation="MAKVIDKHIYFYETHIDVLDEIIATHAEVKNYSEAVRFLCMNYD
                     SEVEKKVNSNQAKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKTISESVTTKSEVFDPTRFLKR"
     gene            750..2339
                     /locus_tag="LP493_002875"
     CDS             750..2339
                     /locus_tag="LP493_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134965.1"
                     /translation="MSKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEKERRTPEE
                     EQELRLIKNALEDFYIPEGETFSESKTGKEFSETSNEAQSLMKHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKVLTHSEQKEYQRLNQAIKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQTFQRGQQKGSIIYQDVVSHDHSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKKNTRKPYTEIENGVSYIVPKG
                     KRRQATLDEMKTNYVHELERFSYEKNRMGMEKRNLLTRKSDLRNTLTKVVKEPVRYDR
                     HAMSLLTEVYKNLPKKRSEWHYGDENRTKLSPYTREKLDELTQYVLTKEPGYQEYIQI
                     SKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKKQDSQIKPLIERMDQ
                     MQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEEK
                     YHASKAYEEQQRRIQMEQERQ"
     gene            2351..2686
                     /locus_tag="LP493_002876"
     CDS             2351..2686
                     /locus_tag="LP493_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134966.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLRNEQF
                     DPNQFLVVEYSATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKSI
                     EESISLTEC"
     gene            2832..>3019
                     /locus_tag="LP493_002877"
     CDS             2832..>3019
                     /locus_tag="LP493_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134967.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGDI
                     LTLNLTTKTFVDAAEDYP"
BASE COUNT         1207 a          438 c          613 g          761 t
ORIGIN      
        1 gaagtaagaa taagaaatgt agatgagaaa atcgtaagag aaattgatcg aagatgtgac
       61 gaactaagta accgaacggg taataaatgg agtcgtaacg attatttaaa gctactcgtt
      121 gaaaatgatt ttgatcgtcc tttgatggaa tataaacaag ataaatttga tcaattatta
      181 aatcagttaa tagataaatt ttcttttgtt caaagtcata atacaaaagt attagaagaa
      241 tatatttgtc agaataatca aattatcgaa cttttaattg aacaaagtag aggaggagaa
      301 gtttaacatg gccaaagtta tagacaagca tatttatttt tatgaaacac atatagatgt
      361 tctagatgaa attattgcaa ctcatgcaga ggttaaaaac tatagtgaag ccgttcggtt
      421 tctatgtatg aattatgatt cagaagtgga gaaaaaagta aattccaatc aagcaaagtt
      481 gaatgcaatg ggaaaagaaa tttctatttt aaccgaaatg gtttcagagt ttgcggatct
      541 ccatttgaaa gatacaggga ttttaattgg tacaaattca actgtttacc aagaagcaaa
      601 agagcgtgtg gaaggcaaga taaaagcaaa tcaaacgaag aaatattctc ctaagataaa
      661 gaaaacaata agcgaatcag tgactacaaa aagtgaagta tttgatccaa caaggttctt
      721 aaaacgataa aaattagaag gagaatgtga tgagtaaatc acctgcagtc attctcactt
      781 gtcaatttac cttgcccaat aaaaaatctt tttcaacata cattgattat atgacaagag
      841 aaaaagcgct ggaagaaaag gaacgacgta cgcccgagga agaacaggaa ctgcgtctaa
      901 tcaagaatgc tttagaggat ttttatattc ctgaaggaga aactttttcg gagagtaaga
      961 cgggtaaaga attcagcgaa acgtcgaatg aagcgcaatc gttgatgaaa catggaatca
     1021 attttgacaa gttagaagaa caagatttta ccaaatatct ttcttatatg acacgtcact
     1081 atgcgttaga acaaaagaaa gtactgacgc atagtgaaca aaaagaatac caacgcttga
     1141 accaagcaat aaaaaaatat caaacagagc cacacaaaaa agcttcagga aatcttcctg
     1201 gagttttttc tatggcttca gacgaagtga aaggaagtga tctgaaggag atcaagcaaa
     1261 ccttccaaag aggacaacaa aaaggctcaa tcatttatca agatgttgtc tctcatgatc
     1321 attcgtatct tgaaaaaata ggattgtacg atcccaaaac agatacttta gatgaagaag
     1381 gtttaaaagc agctggaaga aaaatgatgg agacattgtt cgagaaagag caactgaatg
     1441 aaacaggcta ctggatggca acgattcacc gaaataccaa acatatccat attcattttg
     1501 cagttgttga aaaaaaaaat acgcgtaaac catacactga gattgaaaat ggtgtgagtt
     1561 atatcgtacc gaaagggaag agaaggcaag caacattaga cgaaatgaag actaattatg
     1621 tacatgagtt agaacgtttt tcttatgaaa aaaatcgaat gggtatggag aaacgaaatt
     1681 tattgacacg gaaaagtgat ttgcgtaaca ccttaaccaa agtagtgaaa gagccagtac
     1741 gttatgatcg acacgcaatg agcttattaa ctgaagtata taaaaactta cctaaaaagc
     1801 gttcggaatg gcattacggg gatgaaaatc gaaccaaact ttcaccatac acaagagaga
     1861 aactcgatga gttaacccaa tatgtgttaa caaaagaacc tggatatcaa gaatatatac
     1921 agatttcaaa agcattgaaa gaagaagcaa aaagtcttta tggggaaagc aagagagaat
     1981 caaaggatgc agaaaaaaat gctctctttg atttaaaaaa gcgcacagga aatgccattc
     2041 taacagaact gaagaaacag gatagtcaaa taaaaccttt aatagaaagg atggatcaga
     2101 tgcaatctat ttacaatgaa cgatcctttc gaacacttaa acagttgcca acgaatgaat
     2161 acaaatatag ttacgaagaa ttcatgaagc gcaggaaaca attccaacaa agagttgtca
     2221 cgcaacggag tttgcgtcaa ttaaatcgaa cgattaatgc ccatgaagaa aaataccacg
     2281 caagtaaagc atacgaagag caacaacgaa gaattcaaat ggaacaagaa agacagtagg
     2341 aggaatagca atgaaacaat atttagatca atggaaagtt atagaaggat cattaagaga
     2401 agaacgaatc gaacaacttc ccgattgttt agaaaaagag catttgtttc agataagaga
     2461 aatgttgaga aacgaacagt ttgatccaaa tcaattttta gtcgttgagt actcagctac
     2521 tggtgtgtac tgttgtaatc atgtgaaggg tgaaaaatat tttatcattc aagaatatga
     2581 gggcaagtta gcgccttatt atactacttg ggaaatgaat gaagagggga tcaataactt
     2641 cccgtgtaaa agcattgaag agtctatttc actcacagaa tgttagttgt taagtgaata
     2701 aaagaagtaa aagagtcctg aacgtaattg tccaggactc tttttttcaa tgaattgttt
     2761 tccgccaatt caatgagtgg tgcgatttgc gactacatta tatcaaaaga aagagaaggg
     2821 aggaagaaga aatggcttat tcaacgattg gagttgttgt tgaaaaaagc agagacaatc
     2881 tcgtttttgt gacagaaatt caaacgggca gagcttttgt cgtcacagac aaagcggcaa
     2941 aagcgtatca aagtggcgat attttaacgt taaatctgac tacgaagacg ttcgtcgatg
     3001 cggcagaaga ttatccatt
//
LOCUS       DAFENC010000115         2952 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.122, whole genome shotgun sequence.
ACCESSION   DAFENC010000115
VERSION     DAFENC010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2952
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.122"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            89..406
                     /locus_tag="LP493_002878"
     CDS             89..406
                     /locus_tag="LP493_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBL2134968.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(497..862)
                     /locus_tag="LP493_002879"
     CDS             complement(497..862)
                     /locus_tag="LP493_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134969.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1070..1552
                     /locus_tag="LP493_002880"
     CDS             1070..1552
                     /locus_tag="LP493_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134970.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSTFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1749..2639
                     /locus_tag="LP493_002881"
     CDS             1749..2639
                     /locus_tag="LP493_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HBL2134971.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT         1008 a          460 c          566 g          918 t
ORIGIN      
        1 ttttaaaaca tcacaaggaa aaacttaact atggtattat ctaaacataa ttttttcggt
       61 atttaatatt taattaggag gtaatatttt gcttttttat agtaatttta tcttaatagt
      121 agcgatatta ttacttctga atatatggat ttttgatagg agtagaaatt caagtatagg
      181 ttttagaact aaacgaagtt tgtcttctaa aaaaaattgg gtatactcac aaactatttt
      241 ttatggagga attgttttaa ttagtttact ttcttcaaca ctttattctt tgaatattat
      301 agatgtttcc acctcaaatt caatatctat tattggaatc attattgctg caattattac
      361 acaactgttt ttagtgtttg gagagaagaa aagaagtaaa aaatagaaaa actagtgata
      421 gttttggtga tataagaaaa acatatatgt ataaaaagaa gaaagtagct tctctttgta
      481 catatatggt ttgtttttat ggatgccgag cttttttata agataaggct accgcccata
      541 acgacccaag gatttgtgga actaagtaaa tacctgcaag aagcaagatc agctgggtcg
      601 gttttaaagg atgatagaag taacgccatt cagtaaaatt ggcgcaaaat aaataggaag
      661 tgacagtaga tataatattg gcaatgaata aagatataat acgcctgttc ctttgaaaat
      721 aatatccagc aaaaagagat aaaaatatca atgtgatgaa cccgcttacg gaatgataac
      781 gaaaatcaag cagtaaggcg aaatgcacat aaggaacaaa agataaaagc aacggaaggt
      841 ttttccagca agtttttatc atctttcatc accacctaac aagtgttatt attttgttag
      901 ttttattgta aattgaatcc tgcaataatc aattactttt tcattatttc tagattaaat
      961 gaataaactc tcatgccatt atctctaaaa aaaaagtttt tccccctaat ttttttagat
     1021 agaaaattgt atagtatgat gagagaaaaa gtagtttggg ggaacgttaa tgagaagaaa
     1081 agcagtaatc gatcggcttt atttattttt ttggtttttt cctatcgttt tgctaccttt
     1141 tacatgggta aatgctgttg tacaaggtgc ggagatatta ggcctgatcc aaggaagcgg
     1201 atttgtggtt tctaggaatt ttccagcttt gattgttttc tatttagtga taagtgtagg
     1261 tctcttatta ccaaaatctc tgatcaatca ctacaattgg cagctgcttt acttttcttg
     1321 cttattagta tttacatcta cgttttcttt gctgcctcgc ttgattatcg gccctaatgg
     1381 tttgagcgag agtggattga aggatttagc ttattcctcc atgtatttct tgacgatcaa
     1441 accatggttc tatttagtaa ttgcctcatt tattcttgca acattttttt acttctggac
     1501 agaaatcagg ataaaaagtg aacgatctgt atctataaaa aataactatt gatggtggat
     1561 catcagtaaa aaaacatatg agctgcgtaa aatgcatgtt tctcatatgc tttttttatt
     1621 attatgtaaa gaatgcgaaa aacgtttaca tgatttttac ataacttaac tatattttta
     1681 cagcaaccat acgagggatt tacagtcgac tgataaactt tagttgtaaa taagaaagga
     1741 gcaataaaat gaaaaaagta ttgtttactc taggtatgat gggaattctt ttagccggat
     1801 gcggctcagg atcaggaaat acagatggct ctgccacaca aaataattca agtgactcaa
     1861 atgaacaagt aaaaatcgtt gcggtaggtt cgacagcatt acagccgtta gtcgatgcag
     1921 cacaagaaag ctttgtacaa gaaaatccaa attatcaaat ctctgtacaa ggaggaggaa
     1981 gcggaactgg tttgagccaa gtcgaagctg gagcagttac tatcggaaac tctgatgtat
     2041 ttgcagaaga aagagacgga gttgatgctt caaaattagt ggatcataaa gtagcagtgg
     2101 tcgggatggc accaatcgtc aataaagata cagatgtcaa agatatcacc aaacaggaat
     2161 tgattgatat ctttacagga aaaatcacta actggaagga agttggcggg aaagatcaaa
     2221 aaatcaacgt cgtgaaccgt gcaaacggca gcggtacccg cgcgacattc gaaaaatggg
     2281 gactggatgg tgctacccct gtgcagtccc aagaacaaga ttcatcagga acagttcggc
     2341 agctggtaag tcaaacacca ggagcaatca gctatttagc tttctcatat ctcgatgatt
     2401 ccacacaagc actaagtatc gacggtgtag aaccaaaaga agagaatgta gcagataaca
     2461 gctggggaat ctggtcatat gaacatatgt acacgaacgg aaaaccttcc cctgaagtcc
     2521 aaaaattctt agactacatg atgacagaag aaatccaaga aggacctgtc aaagaattgg
     2581 gctatttacc aatcacaatg atggaagtag aacgtgatca cgaaggaaat atcaaataac
     2641 tagcagataa acatgccacg gtagtcgtta ctattaagga aaaatcaact atgtttcccc
     2701 acatatacat ttttccttta attgtgaaaa atagttcctc atattttgcc gttttttgag
     2761 ctaataccga gggtcagctg attgaacacc gtttattcga aaaaaagagc tacgacatag
     2821 aactgtcgta actttttttg gctcttcgtc aaatcgtgtt ggtgaagaca aatttgaata
     2881 aaacttagac cgatatgcgg cgcgttctgt gcgccgcata tttttttagt tttcaaagat
     2941 cagaccttgt tg
//
LOCUS       DAFENC010000116         2818 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.123, whole genome shotgun sequence.
ACCESSION   DAFENC010000116
VERSION     DAFENC010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2818
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.123"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..383
                     /locus_tag="LP493_002882"
     CDS             <1..383
                     /locus_tag="LP493_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBL2134972.1"
                     /translation="SDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAECFH
                     PKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHAKVN
                     NLSTVTYEQVLSIFNSYLLFNGRK"
     gene            553..813
                     /locus_tag="LP493_002883"
                     /pseudo
     CDS             553..813
                     /locus_tag="LP493_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            976..1641
                     /locus_tag="LP493_002884"
                     /pseudo
     CDS             976..1641
                     /locus_tag="LP493_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            1677..1922
                     /locus_tag="LP493_002885"
     CDS             1677..1922
                     /locus_tag="LP493_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBL2134973.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            2025..>2818
                     /locus_tag="LP493_002886"
     CDS             2025..>2818
                     /locus_tag="LP493_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBL2134974.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLY"
BASE COUNT          984 a          430 c          542 g          862 t
ORIGIN      
        1 cgtctgacat ctatctgatt gttgaagaag gattctacaa gcgtaccttg gatattcacc
       61 gaacactagg gttgctcttg cacactcaag tctcgattca gcaattgctt aagctgccag
      121 cggaatgctt tcatcctaaa ccaaaagtaa acagtgtctt aataaaactt acccgccata
      181 ccacagatgt tccagataaa tattggaagc tatatacgta ctttgtttca aaatgggtca
      241 atcgagaata tcgtcaactg tttactaaaa atcagtttca tcaagcaatg aaacacgcca
      301 aagtaaacaa tttaagtacc gttacttatg agcaagtatt gtctattttt aatagttatc
      361 tattatttaa cgggaggaaa taattctatg agtcgctttt ttaaatttgg aaagttacac
      421 gttactaaag ggaatggaga taaattatta gatatactac tgacagcttc caagaagcta
      481 aagaggtccc tagcgcctac ggggaatttg tatcgataag gggtacaaat tcccactaag
      541 cgctcgggac cccttgtagg aaaatgtcct aagtgtggca acaatattgt attaaaaaaa
      601 tcgttttatg gttgttcaaa ttatcctgaa tgtaagttta ctttagctga acattttaga
      661 aagaaaaaac taaccaaaac gaatgtaaaa gaattactgg agggaaaaga aaccctggta
      721 aaaggaatca aaaacaaaga gaaaaagccc tacaatgccg ttgtaaaaat tggggaaaag
      781 ggatatattg attttatctc tttttcaaaa taaacatggg gctgacccaa aagtagctcc
      841 tatatgaaaa atagaggtct ttccatttag atagtagtgg aaagacctct atttatcttt
      901 tgaaagtgaa tacaaaaata aagcacactc tgctataata taggtgatta atccatttga
      961 gagaggtgct ttatcatgta tcaaaattat accataaacc aactttgttt gcctatagat
     1021 cttgaaatta aattagaaga aaatgatttt gctcatgcca ttgtgcagtt tgttgactct
     1081 attcccgatg aagtctttct tccttattat caatctatgg gtagacccca atatcatcct
     1141 cgtatgctac tttccattat tctttgtgcc tatattcaag gggtttattc gggccgccaa
     1201 atacaaaata tgctgataga tagtattcgg atgcgctact tatctcaaga gcaattccct
     1261 aactttcgta ctattaatcg ttttcgcgtt catccgatta tgaacgatat tctagatcat
     1321 tcatttgttc aatttcgtga gctactggtt caaagtggct taatcagtgg cagtgctcta
     1381 tacattgatg gtacaaaaat tgaagcggat gcgaataaat actctttcgt ttggaaaaaa
     1441 agtattttaa agtataagga tagccttgat caaaaagccc ttgaaaacta ccaacaaatg
     1501 gtggaaacaa aaatcttacc tgagttaata gatgatttaa aggatgaact ttctatagaa
     1561 gagattgaaa ggattcgtca atctttggaa gaaaaggaaa atcaattaat tgaagcgatt
     1621 gaccaaaccg aaacagtaga agggggctga cccattatta ataaggagtg gacaacatga
     1681 ttgatgtaaa tgagctattg gaagaagcta ttagagaaac tgaaaatcta aatgatggcg
     1741 aagtttttct tgttaaagat ttattcaagg gatatgtggg gaataggata cccagaaagg
     1801 atcgacttct gcttggaacg ttatttttaa accatgttag caaaatgaat ggtaatttaa
     1861 aggctattga aaagacttca tctaatcagc agaggtataa aaagacaatt gataagtttt
     1921 aactatcttt tgtgaaatta aaaaaattat aaatatgttg agtagaagca aaagatttgg
     1981 cttggaattt ttacagcagt gaatcgataa aaggagcatg cttgatggta gataatatta
     2041 ttaaatcagt agcagagaaa ttatcctctc tgtcttatat agaaggtatt gttttaggtg
     2101 gttcacgtgc aaggggcacc catacagagg attcggatat agatatcggc atctattaca
     2161 attcagaatc atttgacata aatactatta atcaattcgc tacaaagctg gatgatgagc
     2221 atagaaataa ccttgttgta cctcccggag catggggtga ttggattaat ggcggcggat
     2281 ggttagtcat aaacgggtat catgtggatt taattttacg tgatattaaa cgtgtggaac
     2341 aaataatgaa agatacagag cacggaattg ttactgccaa ttatcagact gggcatcccc
     2401 atggttatat tagtgcaatg tatcgaggag aattagcgat tagcaaaata ctatatgcta
     2461 agaatgaaag cttatgcgaa ttaaaaaaac aggcagaaac ttatcccaat gctttgcaga
     2521 aaagtttagt taactttttt atgtttgaag cagggttctc tttaatgttt gtaaaagcaa
     2581 attcgggaac agacgataaa tattatattg cgggtcatgt ttttcgtata gtttcatgtt
     2641 taaatcaagt gttatttgca tgtaataatg cttattgtat caacgaaaag aaagctataa
     2701 aactgcttga aacttttgaa cataaacctg aaaaatatac cgagaaggta aatcatattt
     2761 ttgaagtact cggtatctca ctttttgaat gctacgacat gaccgagaag ctttataa
//
LOCUS       DAFENC010000117         2804 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.124, whole genome shotgun sequence.
ACCESSION   DAFENC010000117
VERSION     DAFENC010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2804
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.124"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..1148)
                     /gene="ltrA"
                     /locus_tag="LP493_002887"
     CDS             complement(<1..1148)
                     /gene="ltrA"
                     /locus_tag="LP493_002887"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBL2134975.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQK"
     gene            complement(1894..2031)
                     /locus_tag="LP493_002888"
     CDS             complement(1894..2031)
                     /locus_tag="LP493_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBL2134976.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
     gene            complement(2028..2717)
                     /locus_tag="LP493_002889"
     CDS             complement(2028..2717)
                     /locus_tag="LP493_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBL2134977.1"
                     /translation="MKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGEL
                     LKADEKDGMGNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDR
                     AFHAIQDLLKGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQ
                     LTSEPKPYTIERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILE
                     QQSMAIENLII"
BASE COUNT          716 a          621 c          435 g         1032 t
ORIGIN      
        1 tctttttggt ttttgaattg tttatcactt atatgtgatt taacaactaa cttctttctt
       61 ctcggtatca ttttaatctt gaaaccaaga aagtcggagt atctttttct aacatttaca
      121 attcttgttt tttcttgtga tacttccaat tttaatcgtt gttcaatcca ttgagtgatt
      181 gctattttgg ctttttcagc actttccttg tagcggcaga aaactctaaa atcatctgca
      241 taacgaacca tatacatttc ctttaacttt gttttcttca tttctttgta agcgttgctt
      301 ttacatgggc taccgctttt attgatatga accacatagt tttttgtaac aggattttcc
      361 tgccattggc tttctaccca atggtctaac tcattaagaa caatgtttgc tagtagtggg
      421 gatattattc ccccttgcgg agttcctttc tctggatatg ttattgtacc gttagtcatt
      481 ttgattggag cttttaatat cctttttaaa atgaatatca agtgcttgtc ccgtattccc
      541 atagcccata tctgttttat cagcttggaa tggttcacgt tgtcaaagaa acccttaata
      601 tcaaattcaa tcacataatg tagctggctg atttgtaggc ggttataggt tgcttttatt
      661 gcattttcaa ctgacctatt aggtctaaaa ccatagctgt tttcactaaa tttagcttcg
      721 cagattggtt ctaatacttg ttttatacat tgttgtataa gcctgtccca catacaagga
      781 atacctagag gtctggtttt accatttggt tttggtattt cttttcgcct cactggctta
      841 ggtcgatacc catgtggact gcctgcaaca atgtatctta cttttttgac aactgtttct
      901 gctggcaatt tgccaatatc tttaattatt gtaccgtctg ttcctgctgt tttactgcct
      961 gcatttgctt tgatatttcg atatgccagt aatatatttt ctctcgatag gataatatcc
     1021 ataagatgag tgaaaatatc tccattctta cttttggcat ataaatcatc aaaggtgttt
     1081 tgcatttcgt aatattcagc gtgtcttaaa tcttctacac acaatgtttc atttttattt
     1141 ttaggcataa ggcttcactc ctttacttga aattgagtga gcttttttat cttactcgta
     1201 atccttattg aaacaacata atacttttct aatatataca cgacttgagg gcattcctcc
     1261 attctcatta caagaatttc ttaggttcgc cctctgcttt tcagcattag ttcaactgct
     1321 tattgttctt cgtcagttta ttctcttgat gagaacccaa tacctttcct cgttccgata
     1381 atcttatcta tacatatata tccttaggtc actagctata agcctgctgg cttgataccg
     1441 cctgtaacgt tatatggcat ttcataacct atattcttac tttgccacac cagctacgat
     1501 ttctcgtacc tttgcatttc tacaaagttc aaatttagac ccgtacattc gctgtttcgt
     1561 cagttcctta tagaacattc taaccataga tattttatag acccccgacc tgttggatac
     1621 gctacccacc tctggatagt tttcgataga agatatatgt tcatcaacta ttacggtatc
     1681 tttcagccgt ctttaccgag cttcaaacat tctgagtttc ctcatacaat gcttgtcgga
     1741 ggctcagggc aggcgtttca gagcgttact tcatcattcc acctgtcaga ttatcagttc
     1801 tcctaataac caaacttttt cgttctttta ttagtgcctt agcttttcac taaggaacga
     1861 gtcgcacata aattttgtcc gaaattcatc ttgtcacttt cctttctttt ccattgctcg
     1921 atccgctgct gcacttgcat tcatcaagca catcacagta acaccaagca tactgccacc
     1981 aaataccaaa aaaatatctt ttacaattcc catgacgatt cctcttttca tataatcaaa
     2041 ttttcaattg ccatactttg ttgctccaaa atctttttat gtcggtctga taagcgtgca
     2101 ttctgtacca tatcctggat ataggttgtc cgattcaatc gatccaactc cttagccatt
     2161 ttccacgtag gggcgacttg tcggcctagc caattcaagg ttcgttcaat ggtatacggt
     2221 tttggctcgg aagttaattg aatctctttc cgattccgtc caataaaacg cccccattgt
     2281 tcattcaagg gccagttggt tcgcctttta ccttctactt tatccgcaaa tcgcaagtaa
     2341 cgattgataa tggaaaacgt ggtgctctca atgctacgac cttttaacaa atcttgaatc
     2401 gcatgaaaag cacggtcatt tttcagtcga atctcaaaac gatttttcgt ctcagtttgg
     2461 tctaatggaa tccctaactt gatatattgt tcatagtctt tttcatacaa acagaaataa
     2521 acctcactct tgagactgcc gatatataag gtattgccca tgccgtcctt ttcatcagcc
     2581 tttaaaagtt ccccggaacg ataactttta aaggtacgaa acaaggagat acattcttcc
     2641 ttctgacatt ttttcgttag ctcaggtata tccaatagcc ccactcgatc attgattgcc
     2701 aagtccaagc gtttcatcac gccaccggcc tttagacaat cctcgaaaaa gtcgtaccag
     2761 ctacgctttt gagcgagtaa aaaagtttca aattgtcggc aacc
//
LOCUS       DAFENC010000118         2787 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.125, whole genome shotgun sequence.
ACCESSION   DAFENC010000118
VERSION     DAFENC010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2787
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.125"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..493
                     /locus_tag="LP493_002890"
     CDS             <1..493
                     /locus_tag="LP493_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HBL2134978.1"
                     /translation="LVSIHQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGD
                     ILTHFDYGLRRFTFTAEEFAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYR
                     YAVPLYQSVGGKLFTLGSDAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPL
                     PIL"
     gene            526..909
                     /locus_tag="LP493_002891"
     CDS             526..909
                     /locus_tag="LP493_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBL2134979.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            985..1116
                     /locus_tag="LP493_002892"
     CDS             985..1116
                     /locus_tag="LP493_002892"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL2134980.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            1085..1321
                     /locus_tag="LP493_002893"
     CDS             1085..1321
                     /locus_tag="LP493_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBL2134981.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(1399..2370)
                     /locus_tag="LP493_002894"
     CDS             complement(1399..2370)
                     /locus_tag="LP493_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBL2134982.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
BASE COUNT          813 a          586 c          597 g          791 t
ORIGIN      
        1 gctggtaagt attcatcaaa atggccgctt tgattatatg gacgatgtgg ttttaaccaa
       61 agatcccatt caaactacca aggaatattt tgatcagatg ttgcaggtct tgacggattt
      121 tccagaagga gatattttga ctcactttga ttatggatta cgccgcttca ccttcacagc
      181 ggaagaattc gcggagcatt ttgaggctca gctgctaacg attttcaaaa aggttgttga
      241 acgagaattg gcgatggagt taaatgccaa gagcttcttg aaatacggca acgaagacct
      301 ttaccgttat gccgttcctt tgtatcaaag tgtcggcgga aagctcttta ccttaggctc
      361 ggatgctcat gttgccgaag attatcagct gggctttaaa aaaatgagtc agctgttggc
      421 agactgtcag gtagaaaagt tgctagtcat tcaaggaaaa gaacgccgcc tgacgccgct
      481 gccgattttg tgattcctat ataatagaag aaagtggtga aaaaaatgag caacctgtgg
      541 gactacaatc aagaggcacc catccattat ttaattgcgc gacattggga tgcgttgaaa
      601 attgaggcgg tttgccgatc cttgttagca gccgttccaa aacaacaact ggaaaatttt
      661 ttggtggctg acagcttgca gcgggaaaaa gttcaggctt attttgcagc ctttaaagat
      721 cagcctttgg aatatttgca tgcgcagttt catctttttt atcaagtagc cgccccagat
      781 gactacaacg atttacgagg acagctgcaa ttgacctttc aagcggatga aaccgcctat
      841 accgttttat tgggaatggc tcgccttggt gatcaggcga aggtcgagtg gcggattttc
      901 gatatttgat ggcaggatca aggcgtttca gttgcaaacc ttcctctctt tcaattagaa
      961 aaaccgcagc aggaagaagt ttgtgtgctg gtcaccgatg ctggtgaaat tcgtctccgc
     1021 ttatttcctg accaagctcc cctggctgta gccaactggc gctccctagc tgagcaaggc
     1081 gtttatgaca acacaccttt cggctcgtgt cattaaggaa tttgttattc aaggtggcgc
     1141 tttggatggt tctggtgatg aagctgtttc cagctatgag ggctttttcg ctgatgaagt
     1201 gcatcgcgga ctttatcatt ttaatggcgc cttggcctta ggggaccacg gcccccacac
     1261 caacggcaac cagtttttta ttgtgcaaaa cacaaaggcg caggctgacc tgctaatgta
     1321 aagcaagcat acttggagct tggaggacta ccggagctgg atggtcgtta tactgttttt
     1381 ggacaggtat accaagggtt agaaatcgta gcagcgatcg cagctcagcc gacaaacagt
     1441 gaagatgtac cgattgagcc agtgttcatt cgacaaatta acttcgaaaa aacatcgtaa
     1501 aaagacactc actgacttca gcaaaagctc tattcttgag ctggctgcag ctagtgagtg
     1561 tctttcattt atccataaga taaagcttgg attcaataaa taaataaatg ttttggttaa
     1621 agctgtgacc agcaaatgag gaaccgtgcg agccagttga tctgccaatg caaacatttc
     1681 tttaggtgaa ggcgctggcg tgtctgccaa cggatactcc agtcccaatg cttggtaacc
     1741 gtgcatacca tagcagtggt acggtagtaa ttctaacggt acgaaccgat caagatctgc
     1801 cacaaaacaa gcaatcgtca gcagctcggt caggttcata ttgatacctg gaaccacagg
     1861 aactcgaatt cgcacttcgc agttaggata ctcaattaaa aagcgacgaa tattcttcaa
     1921 aatttgttgg ttatctaagc cggtccattg tttgtggagc ttgctggtaa acatttttac
     1981 atccacaaac aatgtatcca catagggagc taccttttgg atttcattat aagcaccaca
     2041 aaagctggtt tccagtacgg tattgattcc aatgtatttc gatttttgca aaatttcttt
     2101 agcaaaatcc gcctgaacca gtgcctcgcc tccgctaatg gtcactccgc catccgagtg
     2161 aaagtaaaaa acagcatcct tctcaatctc atccattacc tcttcagcgg tcatggtctg
     2221 gccaaatcct ttttcaatct gcttgctttg tgattcggga atcgaacacc aggcacagcg
     2281 taatgggcag ccctttaaat aaacaacggt ccgtaaacca gcaccatcat gtagagaacc
     2341 ctgttctatt cttaatactg ttccttccat atagattttt gaattacaca ctagtttaaa
     2401 ctaaaacaca caaggaaaaa cttaccattt aatcataaaa ttagctcata taaatatact
     2461 aggatgtaaa atagactggt caaaatctgg tcaaaaaaga ggactaatac aggtagtcct
     2521 cttttttgtt attttaatat tctaaatcat tttttattgg tttattccct tattcgatgt
     2581 agactcaaat cactatatca ctagatatca aacggcgtca tacggaatca aaaacatcaa
     2641 atttgacctg ttaaatggtc attgaataac attcaaaatc aataaaacgg agtcagacac
     2701 ggagtcaaaa acgctgagag taaaaaatat atacagcctt gtaggtaaag taccacaggg
     2761 ctgtatattt tttatttcag attacct
//
LOCUS       DAFENC010000119         2636 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.126, whole genome shotgun sequence.
ACCESSION   DAFENC010000119
VERSION     DAFENC010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2636
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.126"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..750
                     /locus_tag="LP493_002895"
     CDS             <1..750
                     /locus_tag="LP493_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL2134983.1"
                     /translation="KSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPISCSA
                     RTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEFGHL
                     EGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFKSIT
                     FDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNSVDE
                     FFIQSVASKRNNIPRKSLDYRTIIEHLWKYF"
     gene            2301..>2636
                     /locus_tag="LP493_002896"
     CDS             2301..>2636
                     /locus_tag="LP493_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2134984.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERPVS
                     CGMRTLYRLF"
BASE COUNT          958 a          363 c          527 g          788 t
ORIGIN      
        1 aaatcaaact gtggtagacg tccgcttgtt ttacccgagg aacaatcaga atatattcaa
       61 agaaaggttg ttcaaggatg gacacccgat gtgattgttg gtcgtgcagc gtttcctatt
      121 agttgttctg ctcgtaccat ttatcgtatg ttcaaaaagg ggctatttga ttcttctgac
      181 ttaccgatga aaggcaagcg taaaccgaat ggacatcaag aaagacgtgg aaaacaaact
      241 ttccgccgct ctattcatga acgtgaaaag gattatagcc aattctcaaa tgagtttggt
      301 caccttgaag gtgacactat cgtaggtctg aaacataaaa gtgctgtaat taccttagtt
      361 gaacgattat caaaagttat catcacattg aaaccgtgtg gtagacaagc gattgatatt
      421 gaaaaaaaat taaatcaatg gtttgaatct gtaccgaaaa acctattcaa atccatcact
      481 tttgattgtg gaaaggaatt ttcaaattgg aaacagatca gtaatgtcaa tgatattgcc
      541 atttatttcg ctgatccagg aacgccgtct caaagaggcc taaacgagaa ttctaacgga
      601 ttgttacgta gagatggttt attgaaatct atggatttca attcagtaga tgaatttttt
      661 attcaatctg tcgcatctaa acgaaataat attcctagaa aatcactgga ttatcgaacg
      721 attatcgaac acctttggaa gtatttttga gttacgtaag tattgatgat ctgtctaatt
      781 taatttgaca attaagaaag tattaacttg ttttgtgaaa aagagaattt gaaaaacgat
      841 tggcgaacaa atgctcggta ggtatggtat aaatacagag ctaattggtg tgatgaaatc
      901 agatattcgc gtgagattca gtaaagtagg agttcgaaaa cagctaggtg acaaacagta
      961 ttgctttggt acttcggaat ggtttatcaa attcttatca acagttcact tctctttatg
     1021 tttgagtgat gattcgttag gttattgctt ggaaagaccg gatgagagta gaagagttta
     1081 attttataaa gtgaaaagag gtaatgtacg atatacgtag ggctgaacca atagaggata
     1141 agcaaacgat gttacaggcg caaaattcat agcttactgt tttggagata acagaagagg
     1201 aaataatgca gaagtaaggc gaaaaaagga cggaagccta acagcatatg aaataaagaa
     1261 aaatattata actactgata aatcggtatt gagcaaagta ctaataggag tcaaaaacat
     1321 tcataagcta tgagtgtttc ttggctactt ttttattttt atgtatctac aaaagtttcc
     1381 aggggcagaa cctgtgatta ttaatggaag aacctcaagt attgtcttaa atcattgtta
     1441 tgaaaatgga ttaaaagagt tcatcaaggt gtgattaaca agttactttt cattacatcg
     1501 aatttttcag aagttgctta tattggtgat gatattaatg atttatcatg tatgacatct
     1561 gtgaagaagc gggaggaata gtagaatgtc caaaaaatgc cacaagaaat gagattgaat
     1621 tatctgattt tattgtaact cacagtggtg gtgacgaatc tgtgatagag tttattgagt
     1681 ggatattgga atcgatatag tgtagtagta cagaaaaatt atcatacaat taatactagg
     1741 cataagaata ttggcatatt ctagagttaa aagtaactat tcgaaaagga taaggttaga
     1801 attttttgtt ttgccagtgg aagaatataa aaagggcatt ggaaattaat atattagaat
     1861 gctaagcgga gaaaaaaata tatgaaaagt acgtccttgt gatgggatgg aaaaatacac
     1921 ttatttcaaa caacgataat ataattatgt gaaccgaagt atactcgctt ctaattcaat
     1981 cctcaaatcc cgacagtcgc gacttcaaaa aagcgtatag ttttaatgta tccccatatg
     2041 atccgaaaaa tggtaattta caattaacag tttgatgatg ttgaagatgt ggaaatgctg
     2101 aaattaccat gatgagaaac acattaatta aagggaatta attaactaga atataatctg
     2161 attcaatttg aattaagcaa aaaaaggctg agttttaaat aatcgcgaat tgtaaaatta
     2221 agttagaaaa ataaaaaggc atttatggta cactcaaatt gtatttccga cgaaagaaaa
     2281 caaaggagtg taacccataa atgacctaca aacatcttac catagacgaa ctgacaatga
     2341 tagaatcata ttatcttcaa cataataagc cggttgaaat cgctaaccga atgggacgtg
     2401 ctatacaaac tatttataat gtagtcaata agttcaagca aggcaagact gctcttgatt
     2461 attggcacca gtataaagaa aataagaaaa aatgtggtag aaaagtcatt caattacctg
     2521 ctcatgaagt agattacatt aaagagaaag tcactcttgg ttggacgcct gacgtcatta
     2581 tcgggcgaaa agaaaggcct gtttcatgcg gtatgagaac actttatcgt ttattt
//
LOCUS       DAFENC010000120         2525 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.127, whole genome shotgun sequence.
ACCESSION   DAFENC010000120
VERSION     DAFENC010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2525
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.127"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            24..248
                     /locus_tag="LP493_002897"
     CDS             24..248
                     /locus_tag="LP493_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBL2134985.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            245..1270
                     /locus_tag="LP493_002898"
     CDS             245..1270
                     /locus_tag="LP493_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBL2134986.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGA
                     ANPTLTDGTNHAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADG
                     IYRPDVNQAYNTSGNVGYHVSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRW
                     YLNIPKR"
     gene            1460..1533
                     /locus_tag="LP493_002899"
     tRNA            1460..1533
                     /locus_tag="LP493_002899"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1494..1496,aa:Ile,seq:cat)
     gene            2210..2525
                     /locus_tag="LP493_002900"
                     /pseudo
     CDS             2210..2525
                     /locus_tag="LP493_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          857 a          435 c          492 g          741 t
ORIGIN      
        1 actttattta gggagagaag aaaatgaata ataaaacgtt cgaagtacta aaatggttcg
       61 cactggtaat tattcccgca ctagctactt tcgtggggtt agttggtaaa gcgctcaatt
      121 ggcagtacac agatatctgt gttgtcatca ttactggttt tggcgcgttt ttagggagtg
      181 tgttgggtgt atcaaatcga acctacaaaa tgttctcggc tgaaagcgaa gaaggaggaa
      241 acaaatgaaa aagaaaatta ctattactgc gatgagcctg ttaacggctc tttttttatt
      301 acccattaat acgtttgctt atactattaa tgacgagtat aatttagcgc cgaatcaagg
      361 agactccaga ttagcaattc ctaacaaaat tattttgcac gaaactggaa tagatgcacc
      421 agcaagaaac gtagccgcca acatgaaaaa taattataac ggaagcaatt cttatactac
      481 agatgttatt ggtgacggtg ggattgttta ccgtgtgggt gagcaaggat atgtttcgtg
      541 gggagctggt aacgctaatc cttatgcgcc tgtacagatt gaattacagc gcacatatga
      601 taaagcattg tttgaaaaaa actatcgagc ttatattgaa tatacaagag atagtgcaaa
      661 aaaatatgga attccattga ctcttgatca aggaacttct ttatttacaa aaggaatcat
      721 ttctcatttg tgggtgacaa attatgtttg ggggaaccac acagatccat atggttactt
      781 atcgcaaatg ggagttagca aagaaaagct tgcttatgat ttagctcatg gatttaccga
      841 tgaaaatcca acaacttctg aaaacaagcc tgtcattgat ccaacacgag ctggtgcagc
      901 taatcctacg ctgacagatg gaacaaatca cgcccacatt gatcagtttg gggaaatcga
      961 aaacgcaaac ttgcatgtgg ctggatggca cattgctaac tataaatacg agtatatttt
     1021 cattatggac tacaatactg ggaaagaatt agctcgagta agagctgatg gaatttatag
     1081 accagatgta aaccaagctt ataatacttc tggaaatgtt ggttatcatg tatctttcaa
     1141 tatgcgtaat tttcctagta agaaagtcta tgtaatgatg cgggcaacga atgatccaga
     1201 gggaaacact aaaggcggtg cgcaagattt ccatgacaaa cgttggtatt taaatattcc
     1261 taaacgataa aaatagctcc tcgttgagga gcagtacata actatattga caactataaa
     1321 aattattcga taaaatagtg atgttatcgc atatcttcac tatcacccat aaatagtcac
     1381 actccaagct atgcgataac aggtttgttg ccacacattc tactggttga ttgtttatgg
     1441 ctttatgtgg caacaaccag tacccttagc tcagttggtc agagcagacg gctcataacc
     1501 gtccggtcgt aggttcgagt cctacagggt acattaacgt agccatttga atcgttctgt
     1561 gttagaattt ttttgaagag tattatacaa gctaaagctt ttcttcattg ccactcaaat
     1621 gagtggcttt tttatgtatc cttttatgga ttaatgaaag gatgtttcac atagttatac
     1681 ttctgtatat ttgaaaagtt ttactttgat ttttaaatag aaagacattt gggttaaatt
     1741 gtgagataat aataaagaag agtttaaagc gcaccccaaa ccacttcccc ataagtgtgt
     1801 tacgctttaa actcttttat atttgaagcc attaaaaagc ataccatatt tttgaaaaaa
     1861 agtgagaaaa aaggcttaca attggagtgg tagttaatta gtgacttatt tttgatttta
     1921 tagcactgat actataaaat atagatatca tcatattaca caatcttaat actaacttaa
     1981 aaaatatctc ctttcacaag tatggtgata aaattcgttc cgggctacct ttttaggtag
     2041 cctactttaa tctttatacc tttctggatc aacgaaagta tactttatat agtcataacg
     2101 ccgatgatcg ctacgtgcgt ccggcacgtc agtcatgaat cggctacact agactagaca
     2161 gaaaaaataa ggtgtgtaga ataataaaaa acacactgga ggatttttca tgtcaagacg
     2221 tcaacgaaga acctattcaa aagaattcaa acaacaaatc gtcgatctct atctcgctgg
     2281 taagcctcgc gcagaaatta ttcgagagta tgagcttacg ccttcttctt tcgataaatg
     2341 gatgaagcaa gcacaatcaa cgggctcatt caaagaaaga gacaacttaa caccagaaca
     2401 agcagaattg atcgcactaa gaaagaaaaa taagcaactc gaaatggaga atgatatttt
     2461 aaagcaagcg gcgctgatat tcggacgaaa agacaagtaa ttgatgccaa caagcataaa
     2521 tattc
//
LOCUS       DAFENC010000121         2475 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.128, whole genome shotgun sequence.
ACCESSION   DAFENC010000121
VERSION     DAFENC010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2475
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.128"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            581..1540
                     /locus_tag="LP493_002901"
     CDS             581..1540
                     /locus_tag="LP493_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBL2134987.1"
                     /translation="MTYTHLTPTELVMIEAYFNQSHSVSKVAHLVQRSRQTIYNVYRF
                     LKSGGSAISYYEQYKKNKRNCGRRPIVLPDGQQEYIQKKVAQGWTPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDPHDLPMKGKRKPNGHKEKRGKQAFRRSIQDRTTDYIQFNHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPAGRQAIDIENRLNQWFQSVPKHLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNK
                     VSETFIQSVASKRNHIPRKSLHYRTPLEVFLSYVGKDDLSSLI"
     gene            complement(1527..2132)
                     /locus_tag="LP493_002902"
     CDS             complement(1527..2132)
                     /locus_tag="LP493_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134988.1"
                     /translation="MINSAYFHIKYLKKYEYEEVVLDYGLNRQSFLIYAINNGNLPSN
                     KKNIIIETYAYLEGGSKKLIKSCNIEYQLSVGEIKCVFEEDLELDLKKIFASIHDYIG
                     LIYKIIEDDKQTELNMCYFDREQDFFYYGGMGGGSIVPKINLVELDVNNYRELYVFNS
                     LDFEIPMKQMKNIDIHILPSESCQIEYSIEYFYKVSFVKLS"
     gene            complement(2372..>2475)
                     /locus_tag="LP493_002903"
     CDS             complement(2372..>2475)
                     /locus_tag="LP493_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL2134989.1"
                     /translation="WTCPICHTHHDRDINASINILTEGLRLHSMGLA"
BASE COUNT          825 a          406 c          384 g          860 t
ORIGIN      
        1 aacaataaat gaagactttt ttattgttaa ttgtttattt ttctattatt agatatgaaa
       61 atcgcattta gataaaatag aaaaatatga atatatttta aatattaaga tgagagtcat
      121 taacttatga tagtagtcaa tttgcttttc actaattaca aaatatgtga tataggaagt
      181 ttagttattg ttctcataat gccatcctgt ttttagatta tctagtaatt tttttgttat
      241 ttaaaattag gagcagtgcc aattgtttta attttaaagg ctttttttat atcttctaaa
      301 ttagaagata tttgtatatc aatatggaat atattacctt ttttgtattt ttttatgtta
      361 tctttagcta aaacatcaaa tacatgtcct tgaaattgta tcgaggcagc tggatttagt
      421 ttaaattgag gaaactttac cacagctgat tcaaaacact tgtcacattt ttttattttt
      481 ttaccttcgc cgattgtaaa attaagctag acaactaaaa aagtcatttg tgctacactc
      541 aaaatagttc cgtcgaaaga attataagga gtgagtacaa atgacctata cccatcttac
      601 accaactgaa ctcgtaatga tagaagctta tttcaatcaa tcacactctg tttcaaaagt
      661 agcccatctg gtacaacgtt ctcgacaaac catttataat gtctatcgtt ttcttaaatc
      721 tggtggaagc gcaataagct actatgaaca atataagaaa aacaaacgta actgcggaag
      781 acgtccgatt gtgttaccag atgggcaaca agaatacatt caaaaaaagg tggctcaagg
      841 gtggactcca gatgtcctta ttggtcgagc agagtttcct attgcttgtt cggtacgtac
      901 actatatcgg atgtttaaag ataaaacctt tgaccctcac gatttaccaa tgaaagggaa
      961 aagaaaacca aacggacata aagaaaaaag aggaaaacaa gcttttcgcc gttcgattca
     1021 ggatagaaca actgattata tacagttcaa tcatgagttt ggtcacctag aaggtgacac
     1081 cattgtcggt ggaaaacata aaagtgcggt gatcacgtta gttgagcgat tatctaaagt
     1141 gatcatcacc ttgaaacccg ctggtaggca agctatagat attgagaata gactgaatca
     1201 atggtttcaa tctgtaccga aacacttgtt taaatccatc acatttgatt gtggaaaaga
     1261 gttctcgaat tggaaaaaga ttagtaatac caatgatatt tcgatttatt tcgctgatcc
     1321 aggaacacct tctcaacgag gactaaatga acattcgaat ggcttattac gtaaagatgg
     1381 cttatataaa gctatggatt ttaataaggt atccgaaacc tttatccaat cggtggcatc
     1441 aaaacgaaat catattccta gaaaatcatt acactatcgc acaccattgg aagtattttt
     1501 gagttacgta ggtaaagatg atttgtctag cttaatttga caaacgaaac tttgtaaaaa
     1561 tattcgattg aatattctat ttggcacgac tcacttggca gtatatgtat gtcaatattt
     1621 ttcatctgtt tcataggtat ttcaaaatct aaactattaa aaacatataa ttccctgtaa
     1681 ttatttacat ctaactctac taaatttatc tttggaacaa tagatcctcc acccattcca
     1741 ccataataaa aaaaatcttg ttctctatca aaatagcaca tattaagctc agtttgttta
     1801 tcatcctcaa taattttata aatcaaacct atataatcat gaatgctggc aaaaattttt
     1861 tttaagtcaa gttctaaatc ttcttcgaaa acacatttaa tttctcctac tgataattga
     1921 tactctatat tacatgactt aattagtttt ttagatcccc cctccagata ggcatatgtt
     1981 tcaataatta tgttcttttt attgcttggc aaatttccgt tatttattgc ataaattaaa
     2041 aatgactgtc tatttagccc ataatctaat acaacttctt catactcata tttctttaaa
     2101 tatttaatat gaaaatatgc tgaattaatc aaaactcgag tgttactgtt gttatttatt
     2161 gttgttctat tgtgtataaa attgtatagg ttgtcatatt ttcttggttt agtgaactac
     2221 tcaccactta gctaaaccta acggtttctt acgtttgaag tgggagcttc ttgggaagag
     2281 agcatacttg atagcgtatt actttactaa cagaggtgcc tcttatttac caagctatcc
     2341 ccgtagttcc tacggttctt gtttatttga tctaagccaa tcccatagag tgtagcctta
     2401 gaccttcggt caggatattg atactagcgt tgatatctcg gtcatgatga gtatgacaaa
     2461 tagggcaagt ccatt
//
LOCUS       DAFENC010000122         2405 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.129, whole genome shotgun sequence.
ACCESSION   DAFENC010000122
VERSION     DAFENC010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2405
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.129"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(365..1657)
                     /locus_tag="LP493_002904"
     CDS             complement(365..1657)
                     /locus_tag="LP493_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBL2134990.1"
                     /translation="MARKKRNPDAEKLAESILNAYQPESVDDMQDALKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKEHDNRRNGYGTKTLKTSFGEVAIDVPRDREASFEPELIP
                     KRKRDVSDIEGKVLSMYARGMSQRDIAATVEAIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKARGVEDVFFISMDGVSGLEEGAKAIFPSVIVQRCIVHLVRNALRYIPSK
                     DYKEVCRDMKKFYGASSLNAAHAAFDSFQNRWSHYSGAVDVWKRNFAHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENALLKLLYLRTKELHAKWSGGRIQNWAM
                     VLNQLMINETFSSRMKSMRFTFRNNGRFIQLCVRSKFI"
     gene            complement(1931..2191)
                     /locus_tag="LP493_002905"
     CDS             complement(1931..2191)
                     /locus_tag="LP493_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2134991.1"
                     /translation="MKKIDLINMIGMLIGILVNIVIFTDWLGVLFSNLIPILIIGICG
                     IILSILELFESRNTMNRIFACIILIVNLLPMVYFTFLYFALG"
BASE COUNT          811 a          447 c          367 g          780 t
ORIGIN      
        1 tatgggctac tctgtgatac ttattagcca ttaaactatt ttacccacat agcatatatt
       61 ttgaaatcgt tcattccgta aattcaacta aatatgccta aaaaaataaa aaatctaaga
      121 tagaataaga tttattcagt cttagatgga tttatagcaa ctttttcgta acaactttaa
      181 aaaatacgaa aagaaagagc tgttttactc tgactacgtt gctaaattgt cgtttaatca
      241 ttcatttaaa ccaaatcttt ttttatagaa ttcgttttaa tcctcctgaa tccaaaaact
      301 atgaaaaccg taattaaata gttaagagtt tttaaccacc ataattctct cggctatttt
      361 gaaatcagat aaattttgat cggacacata gttgaataaa cctaccgttg ttacggaagg
      421 taaatcgcat acttttcatt ctagaggaga aggtctcgtt gatcattaac tgattaagca
      481 ccatagccca gttttgaatt cgaccacctg accacttcgc gtgtaattct ttcgtgcgta
      541 aataaagtag ttttaggagt gcattctcat tagagaacgc tccttttttt gtgacttttc
      601 tgaagctgga gtggacactt tcaaccgcat tggtagtgta cataattttt cgaatggcac
      661 taccataatc aaatagttgt tcaacatgtg caaagttccg tttccagaca tctacagcac
      721 cagaataatg agaccaccga ttttgaaaac tgtcaaaagc agcatgtgca gcgtttagag
      781 aagaagcacc gtagaacttt ttcatatctc ggcagacttc cttatagtcc ttacttggaa
      841 tatagcgcaa tgcatttcga acaagatgaa caatacagcg ctgaacaatt accgatggaa
      901 agatcgcttt tgcgccttct tcgaggccag aaacaccgtc catcgaaatg aaaaagacat
      961 cttcgacacc acgtgctttc agttcatcaa atacttgcat ccagcgattt ttagattctg
     1021 tttgatttaa ccataatcct aaaatctcct tatttccttt gagatcatag ccaagaatgg
     1081 tgtatacagc atattctttg gcttcataat tttctcgtaa agtaacatac atacaatcaa
     1141 cgaatagaaa ggcataacac tttgctaggg ggcgggcttg ccattcttcc aattcaggaa
     1201 ggacagcgtc agtgatatct gaaatcattt catgggaaat atcaaagcca taaatagctt
     1261 cgacggttgc ggcaatatct cgttgactca ttcctcgtgc atacatggaa agaaccttcc
     1321 cttcgatgtc ggagacatct cgttttctct taggaattaa ctctggttca aaggaagctt
     1381 cccggtctct aggaacatca atagctactt caccaaaact ggttttaagc gttttagttc
     1441 catagccatt tcgacggtta tcgtgttcct taggctcttt agaatgggca tcataaccta
     1501 aatgattatt caattctcct tgaagcattt tttcaaaaag gggcccaaac acatctttca
     1561 aagcatcttg catgtcatcg acagattcag gttgataggc attcagaatg gattcagcta
     1621 acttttcggc atcaggattt cttttctttc tagccatcgt gtaatcacct cttgatctta
     1681 ttgtagaaaa agaaaaaccg cgaagcaacc acctgcctag gattaatggt tacttacacg
     1741 gtttatatta cactctcatc attaaaaaag tatctttcga tattactaaa caatgaaatt
     1801 atctatttga aatttaaatc tgataatata ttgagtgttc caatgagggc tttgatccta
     1861 ttatccatat ctttttcagt tttaatattg atacacatta taagaaaaag aaacttttgg
     1921 ttaatttatt tcatcccagt gcaaaatata aaaaagtaaa atagaccata ggcaatagat
     1981 taacaattaa tataatacaa gcaaatattc tattcattgt atttctgctt tcaaaaagtt
     2041 ctaatattga aagtataatt ccacaaatgc ctataataag tatgggaata agattagaaa
     2101 ataacacccc gagccaatct gtgaaaatta ctatatttac taatatccct attaacatac
     2161 ctatcatatt tattaaatca atttttttca ttagatattt ctcctttatt aaatctgaag
     2221 tacttatatt aaaataattc taaactattt acctcaaaaa gtgcaataaa ttatttctga
     2281 acaataaaat gatagtcaaa acaaaaaaat attgttaatc gttcagagcc atccgagagt
     2341 gtaaaatatt ttgtgtaaat gaaaaaatcc atacaaaaaa ggaaggcgct tctgtagaat
     2401 aaagt
//
LOCUS       DAFENC010000123         2398 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.130, whole genome shotgun sequence.
ACCESSION   DAFENC010000123
VERSION     DAFENC010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.130"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            207..2069
                     /locus_tag="LP493_002906"
     CDS             207..2069
                     /locus_tag="LP493_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL2134992.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2398
                     /locus_tag="LP493_002907"
     CDS             2069..>2398
                     /locus_tag="LP493_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL2134993.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          865 a          353 c          466 g          714 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataat
//
LOCUS       DAFENC010000124         2300 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.131, whole genome shotgun sequence.
ACCESSION   DAFENC010000124
VERSION     DAFENC010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2300)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2300)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2300
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.131"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(45..1364)
                     /locus_tag="LP493_002908"
     CDS             complement(45..1364)
                     /locus_tag="LP493_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBL2134994.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(1361..2014)
                     /locus_tag="LP493_002909"
     CDS             complement(1361..2014)
                     /locus_tag="LP493_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBL2134995.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
BASE COUNT          760 a          359 c          195 g          986 t
ORIGIN      
        1 ataagtctct atttttcaat aactattgca aaattatatc ttaattaaga aaatattttt
       61 attttaaaga taaaaaattc ttcatcctgc aatactttat attctatatt gtaattattc
      121 agaatattac ttacaatata taaacctaat ccattactat tttccttatt taaatcaaat
      181 ttaacatcaa atattttatc catattcgaa attttattgt taccgtatga attctctata
      241 tataaccaat cattaactat cccaatatta attaccccat ttacatcagt atattttacc
      301 gcattactaa tcaaattaga tagaataatc tttaaagctg tttttcctat ataaacattc
      361 tcgtctaata tataattatt gacagttatt ttcttttgat ttgctaatat ttcatacttt
      421 tttaatatgt cttctaatgt atcatttatt ttcaaatatt cttcatcatt attcaaattt
      481 tctatagaat gaactgataa tatttgagaa atattttttg ttaaactatc aacgatttca
      541 atacattcat taatataaat atctctttct ttatattttc caatattgta tttcatgttt
      601 tccagtatta ttttaagact agcaagaggg gttttaagtt catgggatgc acctttaaaa
      661 aagtcatatt ttaacttttc taattttaaa atttctttat ttttaaattc caaatcgtca
      721 attgttctta ataaagtaga atacaaatca ttaatttgtt gttttaattc tccaacttca
      781 tcattagagc taacttttaa actcattttt ttatcaagtt tcatcatttt atcagtaaca
      841 atttttattt cttgtatatt attttttatt gattttgcat aaattaaaga aataatagca
      901 gaaaataaaa ttgatattaa taaagaatat ggtaaaaatt taaggcttaa atctttcgca
      961 tctttttgca tatcagctgt agaaacaaat tgtagatttg tttttttacc atcattaagc
     1021 tttatttctc tttcttcaat tatcaaagaa ttactatcac tttctaaatt aacatttata
     1081 ttatctttga tttgtatttc attcttatta tttttttctt ttatgaatac ttttatttca
     1141 ctactcttgg aataaaactc caaagtttgt tctatatatt ttatttcttt tccattcata
     1201 ttactagaaa tttcatttgc catattatga atcttttctt ttctcgtctc caaatatgtt
     1261 ttaggaaaga taaaaaaaat taatgaatga actaatataa ttattattcc aagaacagaa
     1321 aatatttgta tgaacatttt tggaaatatc tttaattttt tcattttctc tccaatttat
     1381 atcctacatt tcttatagta gttatacagt ctaattgtaa tttttttcta agttctttta
     1441 tatatacatc tattactcga tcataaggag tttcttcgct atctttccat acataatcaa
     1501 taatttgcat tcttgttaac acttgtccat tattatccaa taaacatttt aatacttcta
     1561 gttcttttgc atttacatct atttcttcac catttatttt agctgtatag ctattaaaat
     1621 taaccgatag atccttatat tcaaacttct ctaaatgtcc ataattcttc ttaattaaag
     1681 aatctattct agcttttaag accggcaatg aaaatggctt ttctacatat ccgtctacta
     1741 aattagtaaa tgcatcaatt ttatattctt catcactaaa tgcagtcaag attagaattg
     1801 gtaaattgct tttctttcta atttctttca acacttctaa accatttata aaaggtatct
     1861 gaatgtctaa gataaccaaa tttatatcgc tattaaattt tgacaaggct tctcttccat
     1921 ctttagcttg aataacagta tatccaaatt ctgaaagata ttcacttatt ccctctctta
     1981 tcatattatc atcttcaaca gttaatattt tcatatatac ctccacttaa gcctatacac
     2041 tagatattat acagcatatt atggctctat aatatctagt gttggtgacg ccttctgttg
     2101 ccaatacttt ttcttttttt taataaatgc aaacagacac cttgaaatcc tttagaaaaa
     2161 aggcttctat aatattttgt gttgttggaa aatcgaaggc gattttctac taacactttt
     2221 tcttcgtttc aactcaaaaa gagactcact tttggtaaaa tttagtcgac caaaacatca
     2281 ccctaccaaa ggagtcgctc
//
LOCUS       DAFENC010000125         2280 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.132, whole genome shotgun sequence.
ACCESSION   DAFENC010000125
VERSION     DAFENC010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2280
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.132"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..1443)
                     /locus_tag="LP493_002910"
     CDS             complement(<1..1443)
                     /locus_tag="LP493_002910"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HBL2134996.1"
                     /translation="MTEQIEKNSKSLYQALWNSADILRSKMDANEYKSYLLGLVFYKY
                     LSDNMLRYVSVLLEEETDDLNKAQDLYVEAFKDADIKDDLLYELKDEFSYTIAPALTF
                     TAQVAAIHDGSFQLEDLVQGFRDIEQSSENFENLFEDIDLYSKKLGSTPQKQNKTIAD
                     VMKELEGLNMAGHAGDVLGDAYEYLIGQFASESGKKAGEFYTPQPVAKLMTQIVLQGK
                     EDKKGFSVYDATMGSGSLLLNAKKYSHQPGTISYFGQELNTSTYNLARMNMILHGVPI
                     ANQHLHNADTLDQDWPTEEPTNFDGVLMNPPYSAKWSADKGFLDDPRFSAYGVLAPKS
                     KADFAFLLHGYYHLKDTGVMAIVLPHGVLFRGGAEGKIRKALLENGAIDTVIGLPANI
                     FFNTSIPTTVIILKKDRAKKDVLFIDASQDFEKIKTQNTLRDYHIDAILEAYKTRTIK
                     DKYAYVAEFDEIVENDYNLNIPRYVDTFEEE"
     gene            complement(1781..2176)
                     /locus_tag="LP493_002911"
                     /pseudo
     CDS             complement(1781..2176)
                     /locus_tag="LP493_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443455.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt transporter"
BASE COUNT          658 a          429 c          397 g          796 t
ORIGIN      
        1 ttcttcttca aaggtatcca cgtaacgggg aatgtttaag ttgtaatcat tctccacaat
       61 ttcatcaaat tctgcgacat aagcatactt gtctttaatt gtacgggttt tataggcctc
      121 taaaatagcg tcaatatggt aatctcgtag cgtattttgc gtttttattt tttcaaaatc
      181 ttgtgacgca tcaataaaga gcacatcttt tttcgcacgg tctttcttca agataattac
      241 ggtcgttgga atggacgtat taaagaagat gttagcaggt aagccaatga cggtgtcaat
      301 ggcaccattt tctaacaagg ctttgcgtat cttcccttct gcgccccctc taaagagcac
      361 cccatgtggc aaaacaatgg ccatgacgcc cgtatctttc aaatgatagt agccatgtaa
      421 taagaaagca aagtccgctt ttgatttagg ggctaatacg ccataggcag agaagcgtgg
      481 gtcatctaag aagcctttat cagccgacca ttttgcagaa tacggtgggt tcatgagcac
      541 cccatcgaag ttcgttggct cttctgttgg ccagtcttga tccaaggtat ccgcattatg
      601 caagtgttgg ttggcaatgg gaaccccatg caaaatcatg ttcatacgcg ccaaattata
      661 ggtagacgta ttcaactctt gtccgaaata agaaatggtt cccggttgat gggaatattt
      721 tttagcgttc aaaagtaacg agcccgaacc catggtcgcg tcgtaaacag aaaagccttt
      781 tttatcttct tttccttgta aaacaatttg tgtcatcaat tttgcgaccg gttgtggggt
      841 atagaattca ccggcttttt taccggattc agatgcgaat tggccaatta agtactcata
      901 ggcatcgcct aagacatcgc cagcatgccc cgccatgttt aacccttcta attctttcat
      961 aacatctgcg atggttttat tttgtttttg tggggttgac cccagttttt tagaatacag
     1021 atcaatgtct tcaaataagt tctcaaagtt ttcgctggat tgttcaatgt cacggaaacc
     1081 ttgtaccagg tcttctaatt gaaaagatcc atcatgaatg gctgccactt gcgcggtaaa
     1141 ggtcaatgcg ggtgcgatgg tatatgaaaa ctcatctttt agttcataca agagatcatc
     1201 ctttatatct gcatctttaa atgcttcaac gtaaaggtct tgtgctttat ttaggtcgtc
     1261 cgtttcttcc tccaatagaa cggagacata ccgcagcatg ttgtcggata agtatttata
     1321 aaagaccaag cctagtaaat agctcttgta ttcattagcg tccatttttg aacgcaggat
     1381 atctgcggaa ttccacagtg cctgatataa gctttttgaa tttttttcga tttgttctgt
     1441 cattggttat tttcctcatt cgtgttgtat tttttataaa tcagtttttt aaaaaattag
     1501 ttactatttg aacttgtttt ttcaccatat gtattttaat gaaatggata agctacattt
     1561 gcttagacaa ttcatgtctt acttaattct tattataaca aacctatttc acctttttcg
     1621 atacattaaa taataagtaa cttaaaataa ggttcgaata accttgttaa atagtggttt
     1681 tcttatctta tagtatagaa atcaagagat tacttccgat ataacatttt tttaaaaaaa
     1741 ttagattgta atgtttttta tattcattct aaattttcac ttaaaaagga taatcattaa
     1801 aatcatcaaa ttcagtaata tatattttct tactcatttt aatatatttc tcttcgtctt
     1861 taatggtccc ttcataaaaa gatttcttag catcttcatt tagccagtct acagaaaaca
     1921 tctgattaga gacaggatct ttgattttag atacaaattc ggatgataaa acactatcaa
     1981 acatttctcc aaaaatggtg gtcaatcttt gaaaccatat catcataaat tcagtatttg
     2041 gctttaaagc atatttgttt ataatcattt caactatttc tctagcctta ctctcatttt
     2101 cgaaatttaa taactgccct ataattaaga cacactgcgg caaagaaccc gggttattta
     2161 tcatgatatc taccaggtgg aatggcaaca ctttttttga caaaaattat aaggtgttgt
     2221 gaatgctgcg gtgttatggc tccgattgcc cttgacaatg agcatcctcg gatctgattt
//
LOCUS       DAFENC010000126         2169 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.133, whole genome shotgun sequence.
ACCESSION   DAFENC010000126
VERSION     DAFENC010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2169)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2169)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2169
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.133"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..113
                     /locus_tag="LP493_002912"
     CDS             <1..113
                     /locus_tag="LP493_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2134997.1"
                     /translation="YAVKLYKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            327..1022
                     /gene="vanR"
                     /locus_tag="LP493_002913"
     CDS             327..1022
                     /gene="vanR"
                     /locus_tag="LP493_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBL2134998.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            1000..2154
                     /locus_tag="LP493_002914"
     CDS             1000..2154
                     /locus_tag="LP493_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HBL2134999.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT          732 a          400 c          461 g          576 t
ORIGIN      
        1 attatgcggt aaagctatat aaagaaggaa atatgactgt aaatcaaatt tgtgaaatta
       61 ctaatgtatc tagggcttca ttatacagga aattatcaga agtgaataat tagccattct
      121 gtattccgct aatgggcaat atttttaaag aagaaaagga aactataaaa tattaacagc
      181 ctcctagcga tgccgaaaag ccctttgata aaaaaagaat catcatctta agaaattctt
      241 agtcatttat tatgtaaatg cttataaatt cggccctata atctgataaa ttattaaggg
      301 caaacttatg tgaaagggtg ataactatga gcgataaaat acttattgtg gatgatgaac
      361 atgaaattgc cgatttggtt gaattatact taaaaaacga gaattatacg gttttcaaat
      421 actataccgc caaagaagca ttggaatgta tagacaagtc tgagattgac cttgccatat
      481 tggacatcat gcttcccggc acaagcggcc ttactatctg tcaaaaaata agggacaagc
      541 acacctatcc gattatcatg ctgaccggga aagatacaga ggtagataaa attacagggt
      601 taacaatcgg cgcggatgat tatataacga agccctttcg cccactggag ttaattgctc
      661 gggtaaaggc ccagttgcgc cgatacaaaa aattcagtgg agtaaaggag cagaacgaaa
      721 atgttatcgt ccactccggc cttgtcatta atgttaacac ccatgagtgt tatctgaacg
      781 agaagcagtt atcccttact cccaccgagt tttcaatact gcgaatcctc tgtgaaaaca
      841 aggggaatgt ggttagctcc gagctgctat ttcatgagat atggggcgac gaatatttca
      901 gcaagagcaa caacaccatc accgtgcata tccggcattt gcgcgaaaaa atgaacgaca
      961 ccattgataa tccgaaatat ataaaaacgg tatggggggt tggttataaa attgaaaaat
     1021 aaaaaaaacg actattccaa actagaacga aaactttaca tgtatatcgt tgcaattgtt
     1081 gtggtagcaa ttgtattcgt gttgtatatt cgttcaatga tccgagggaa acttggggat
     1141 tggatcttaa gtattttgga aaacaaatat gacttaaatc acctggacgc gatgaaatta
     1201 tatcaatatt ccatacggaa caatatagat atctttattt atgtggcgat tgtcattagt
     1261 attcttattc tatgtcgcgt catgctttca aaattcgcaa aatactttga cgagataaat
     1321 accggcattg atgtacttat tcagaacgaa gataaacaaa ttgagctttc tgcggaaatg
     1381 gatgttatgg aacaaaagct caacacatta aaacggactc tggaaaagcg agagcaggat
     1441 gcaaagctgg ccgaacaaag aaaaaatgac gttgttatgt acttggcgca cgatattaaa
     1501 acgcccctta catccattat cggttatttg agcctgcttg acgaggctcc agacatgccg
     1561 gtagatcaaa aggcaaagta tgtgcatatc acgttggaca aagcgtatcg actcgaacag
     1621 ctaatcgacg agttttttga gattacacgg tataacctac aaacgataac gctaacaaaa
     1681 acgcacatag acctatacta tatgctggtg cagatgaccg atgaatttta tcctcagctt
     1741 tccgcacatg gaaaacaggc ggttattcac gcccccgagg atctgaccgt gtccggcgac
     1801 cctgataaac tcgcgagagt ctttaacaac attttgaaaa acgccgctgc atacagtgag
     1861 gataacagca tcattgacat taccgcgggc ctctccgggg atgtggtgtc aatcgaattc
     1921 aagaacactg gaagcatccc aaaagataag ctagctgcca tatttgaaaa gttctatagg
     1981 ctggacaatg ctcgttcttc cgatacgggt ggcgcgggac ttggattggc gattgcaaaa
     2041 gaaattattg ttcagcatgg agggcagatt tacgcggaaa gcaatgataa ctatacgacg
     2101 tttagggtag agcttccagc gatgccagac ttggttgata aaaggaggtc ctaagagatg
     2161 tatataatt
//
LOCUS       DAFENC010000127         2159 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.134, whole genome shotgun sequence.
ACCESSION   DAFENC010000127
VERSION     DAFENC010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2159
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.134"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(132..1085)
                     /gene="menA"
                     /locus_tag="LP493_002915"
     CDS             complement(132..1085)
                     /gene="menA"
                     /locus_tag="LP493_002915"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HBL2135000.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(1098..2153)
                     /locus_tag="LP493_002916"
     CDS             complement(1098..2153)
                     /locus_tag="LP493_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBL2135001.1"
                     /translation="MVLTGCSNSANKTTTESSAATKILKDPYSDEQFLLGTYVRIRVY
                     DEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKPVKVSDDVYTLVKRAYE
                     YSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLVDYHKIELNDKEKTVYL
                     KEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVYVLGHSPRGENQDWTVG
                     IQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHLFDPKTGYPFDNDIASV
                     TIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFVTKDDKVYVTDPIKDTF
                     KLSEDSHYTMGDRSELK"
BASE COUNT          655 a          460 c          384 g          660 t
ORIGIN      
        1 tgataaacgg tgttcaaaag cttgcatctg cggtaataag cccaaccaaa cgaaaaatat
       61 aaggagctat ttttatttgg ctgttcttat tacttgatgc agggcagttt tttcacaacc
      121 tcttcatgct gttaaatggc ttgcataatg attgttagta atagccccaa tacataactg
      181 gcattgaata agaccatatt tttgatggaa tagctgaaac tgataggctg gggtaacgtt
      241 tgcttgaatt gatccaaatg cttcttcaca attggcaagg tcaagaaggt gaccaagatc
      301 ggccattcat agataccgct caacaacccc attaaaatca cgaaatagca agcatacatc
      361 aatagctgga ataagactgt tcccgcagga cgtccgatat aaaaaactag tgtatagcga
      421 tgattttcaa tatcacggtc aagatcccgc aaattattag ccaacatgat attggcaatc
      481 gtaaacacca agggtaagga agctaatacg attgctgcta tagcccaaag atttcctacc
      541 aaagcaaatt gtccagatga aaagttgact gtcagatcat agacatctga accgaatgta
      601 ttgacataaa cgaccatggc aaaaattcca aggcccatag tcaccccact gaaaatttcc
      661 cctaaaggca ttcgagataa aggaatcggt ccgaatgtat agaatactcc aataaaacaa
      721 cagataaatc ccatcaaaag taaaagccaa cccgtattga tcgttagaat aacgccgata
      781 acaaaaacaa atgcaatcat agctaaaatc atgtttcgaa tcaatacagg agatagattt
      841 ctgcggccaa tgacattttc ttcatactta tatacttcag aatgagcctt ttcataatcc
      901 atgtaattat tgatagcggt agtcgctaaa tcaaaaacta gcattccaat aaaaaataaa
      961 aaagtgttta gccaatgtat ctcatgaaaa aaagcgatag agaataatac ccctaccgca
     1021 aaaggaaata cactagccac ctttgttcgt atttcaacta cttctaaaaa gatttttagt
     1081 gtcatggttc gtactcctta ttttagttca gaacggtcac ccatcgtgta atgggagtcc
     1141 tccgataatt tgaaggtgtc tttgattgga tcggtcacat atactttatc gtcttttgtc
     1201 acgaagatcg cttccgtccc gttattcaat tcgctttcga cgtattccag tccttttttc
     1261 acacccattg aaaagactgc tgtagacaac ccgtcaccat caattgattt atctgttatg
     1321 atcgtgacac ttgcgatatc attgtcgaac ggataacccg tttttggatc aaacaaatga
     1381 tggtattttt tgccatctac ttctaaataa cgctcgtaaa ttccagaggt aactaatgtt
     1441 ttgttccgtt ctttaataga acctaaaaca gatccgcgag ccatgttcgg atcttggatg
     1501 ccgactgtcc agtcttggtt ttcgcctctt gggctgtggc ctaagacata gacattaccg
     1561 cccaagtcaa cgatggcagt ggtcactcct tgttttttca agactttcac tacttcgtcc
     1621 gtaatgtaac ctttggcgat tgcacctaaa tcgatgatca ttcctttttc ttttagataa
     1681 acagtttttt ctttgtcatt tagttcgatc ttatgataat ccactaattt caatgcctga
     1741 tcgatttctt cttgggaagg ttttctggcg tcatcaaaac cgattcgcca taattgtgtg
     1801 attgcaccaa tcgccatatc gaatccgcct tgagaatctt ggctatattc gtaggcccgc
     1861 ttgactaacg tgtagacgtc atcagaaact tttactggtt tgatcccagc ttgctcattc
     1921 acttcatcga tctcagaacc tttttgattg atcgtgattt tatcaccaag ttcttttact
     1981 cgatcgaagg caggtttcaa tgctgattct ttgccttcat catacacacg gatacgaacg
     2041 taagtcccta acaagaactg ttcatcagaa tatggatctt tcaatatctt ggtagctgct
     2101 gaactttcag tggttgtttt atttgctgag ttgctgcagc cagttagcac cataaaaga
//
LOCUS       DAFENC010000128         2003 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.135, whole genome shotgun sequence.
ACCESSION   DAFENC010000128
VERSION     DAFENC010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2003
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.135"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..378
                     /locus_tag="LP493_002917"
     CDS             <1..378
                     /locus_tag="LP493_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBL2135002.1"
                     /translation="KNVSTEDFFNYCRLEESGVTVTSGTDLPLFITDIPESIIRAVFR
                     RFPEGEEVWEKETSFTTTELLKSFTSNSFKVNGLSEYGEIKVGKSASLAVFSEDLCTD
                     DWQKVMAAEVIATYLDGDLVYKK"
     gene            426..1826
                     /gene="yfcC"
                     /locus_tag="LP493_002918"
     CDS             426..1826
                     /gene="yfcC"
                     /locus_tag="LP493_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBL2135003.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFLGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
     gene            1859..>2003
                     /locus_tag="LP493_002919"
     CDS             1859..>2003
                     /locus_tag="LP493_002919"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2135004.1"
                     /translation="MIKINQLAGMNIHYLFYSLKEFFAYQQKIGISSVELWGGAPHFF
                     IDAF"
BASE COUNT          555 a          339 c          432 g          677 t
ORIGIN      
        1 aaaaatgttt ccacagagga cttctttaat tattgtcgat tagaggaaag tggtgtaaca
       61 gtcactagcg gtacagattt accgctgttt attactgata ttcctgaatc gattataaga
      121 gcagtattcc gtcgttttcc tgaaggagaa gaagtctggg agaaagaaac aagcttcacg
      181 acaaccgagc tgctgaaaag ttttacaagc aacagcttca aagtaaatgg tttatcggag
      241 tacggagaaa taaaagtagg gaaaagcgcc agcttagctg ttttcagcga ggacctctgt
      301 actgatgact ggcaaaaagt gatggctgcg gaagttatcg ctacctatct tgatggtgac
      361 ttagtttaca agaaataatg cttttcgata taacgttata aaacgaatta aagagaggtt
      421 aaaaaatgga aacaatgaaa agaaaattca ccttcccaca tagttataca ttgattttta
      481 tcttaattat tttggctgca attttaactt ggataattcc tagtggtcag tttgagacag
      541 ttgttgaaaa cgtcgcaggt atggaaaaaa caacggttgt tccgggaacc tatcaccaaa
      601 tcgataaggc agattatgga caaggttttt cctctatact aatggcacca gctgaaggga
      661 ttatttcagc tgttgaggtt gttgcttttg ttctcatcgt tggtggtgcc ttcgggatta
      721 tcctaaaaac gggagccatc gatcgagggc tgtttacctt agcaaaagtt ctgggagaca
      781 aggggatctt agttattccg atgtcgatga ttctattcag cttaggagga tcaacctttg
      841 gcatgagcga ggaagtcatt cccttatttg cggtgtttat ttctctgatg ttttctcttg
      901 gctatgattc catgactgcg atcttgattc tatttttaag tacacaagcg ggatatgttg
      961 ggtcgacgat taatcccttc aacgttttaa tcgcacaggg agtagctggc gtttacggaa
     1021 atcccctgct ttggtttcgg atgctatcct ggattgtcat tactgggatt tcaattgttt
     1081 tcaccatgct ttatgctagc agagtcaaaa agaatccact gtcctctatt gtttatgaga
     1141 gtgatttaaa ggttaagcat aagtttcaaa attttgacac tgaaaaagag ttttcaacac
     1201 aagataaact aattatcgcc ggttttatcg taggtttagg aatcatgatt tggggtatca
     1261 tttccaaggg atggtatatg gttgaaattt ctgcactatt cttaggatta ggtctttttg
     1321 ctgggggcat cgctagattt tctcaaaagg aaattgctga agcttttgtc gaaggctgtt
     1381 cagatttcgc ctatgctgct gtaatcattg ggctagctag aggagtcttg gtaatcttgg
     1441 aaggtggaat gattattgac actattctaa acagcttggc taacctttta ggtggtcttc
     1501 caaaattcct gttcactacg attctactca tttctcaagt aattgtttcc ttttttgttc
     1561 catcctcctc aggagctgcg gcattaacga tgccggttat ggcaccattg ggtgatctaa
     1621 tgaatgtaag tcgtgatgtt gttgttctaa gtaaccagtt tggaaatggt ttaatgaata
     1681 ttatctcccc aactagtggt gtattactgg caggattagc catcgcagag attaatttct
     1741 ctaaatggtt taaggttggc ttcaaaatat ttgccatctt aacccttgtt tctgctgttt
     1801 tgttatacat tgctacactc ttttagtctt aatcatccat taataggagg caatagttat
     1861 gattaaaata aatcaattag caggaatgaa tatccactat ttattttatt ctctcaaaga
     1921 atttttcgct tatcaacaga aaattggtat ttcttctgtt gaactttggg gaggtgctcc
     1981 gcattttttc atagatgctt tta
//
LOCUS       DAFENC010000129         1708 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.140, whole genome shotgun sequence.
ACCESSION   DAFENC010000129
VERSION     DAFENC010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1708
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.140"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            24..641
                     /locus_tag="LP493_002920"
     CDS             24..641
                     /locus_tag="LP493_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011834674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2135005.1"
                     /translation="MWIFKQEIFAKLFSLDGLGWGILFFIFLFLGSMWIWFVDKKNSY
                     EKVIVKKMNRNEFDDFSKEHRVELYDSHEINSTSPSYYWVFGCEEKPLEIKLLKMLEN
                     PPVIEDFSAKNVEKQMFEQVQIRGQNKISLEPDEYAAFFLETNSGTSMPVFKVKLKMN
                     GRLCTYDLVANMRYGSTGDRRTILKFEQTFRSFLKNRVSQIFNLD"
     gene            805..1137
                     /locus_tag="LP493_002921"
     CDS             805..1137
                     /locus_tag="LP493_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2135006.1"
                     /translation="MNNREILAKEMADLKAKEAKIRAKRKQIRQKEMISLAKLYCKKE
                     GFKTPAEALDFLESNKRNHSVNDEVLVSLRKFADGLVWQENGAYWRTNDVKGLTQFMA
                     QFRSENVN"
     gene            1461..1622
                     /locus_tag="LP493_002922"
     CDS             1461..1622
                     /locus_tag="LP493_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HBL2135007.1"
                     /translation="MAYMVARTQKHKVGSLNGLQNHVDRKTKNHTNKDIDITKSGSVA
                     KFSKKSILV"
BASE COUNT          620 a          200 c          337 g          551 t
ORIGIN      
        1 tttaaagtgg gaggaaaatt gttttgtgga tatttaaaca agaaatcttt gctaaattat
       61 ttagtttaga tggattaggt tggggaatct tattttttat ttttttattt ttaggatcta
      121 tgtggatctg gtttgttgat aaaaaaaatt cttatgagaa agtaatagtg aaaaaaatga
      181 atcgaaatga attcgatgat ttttcaaagg aacatagagt tgaattgtac gatagtcatg
      241 aaattaacag tacttctcca tcttattatt gggtatttgg ttgcgaagaa aaaccattgg
      301 agattaaatt gttgaaaatg cttgaaaatc ctccagtcat tgaagatttt tctgcaaaaa
      361 acgttgaaaa acagatgttt gaacaggtac aaataagagg tcaaaacaaa atttcattag
      421 aaccagatga atatgcagcc ttttttttag aaacaaattc aggtacttca atgcctgttt
      481 tcaaagttaa attaaaaatg aatggtcgtt tatgcactta tgatcttgtt gcaaatatgc
      541 gctatggttc tactggtgat agacgtacta ttttaaaatt tgagcaaacc tttagaagtt
      601 ttttgaaaaa tagagtatcc caaattttta atttggattg aaaaaattaa aaatttggcc
      661 aaaaatacta cagtttttta gagcaatcat cttatgatga ttgctctttt tttgttgttt
      721 ttgtgtcatt cgttgttcaa atcctctatt cgtaaaataa atattttaaa ctagaaatat
      781 gccttatttt taggaggaat caaaatgaac aatagagaaa tattggcaaa agaaatggcg
      841 gatttgaaag caaaagaagc gaagattaga gcgaaacgaa aacagattag acagaaagaa
      901 atgatttctt tagcgaaatt atattgtaaa aaggaaggct ttaagacacc tgctgaagca
      961 ttagattttt tggaatcaaa taaaagaaat cattcagtaa atgatgaggt tttagtatcg
     1021 ctaagaaaat ttgcagatgg attagtttgg caagaaaatg gtgcatattg gcgtacgaat
     1081 gatgttaagg gtttgactca atttatggca caatttcgtt cagaaaatgt gaactaaatt
     1141 gaggaggggt tgaagtgaaa agcaatactt ttcacttttg gttttttgcg gaataaaaat
     1201 tgtgaaaaca atgacgcaaa aagccaatgg ttttgaacga aaaaaggacg taaaaaagga
     1261 atgcgaaggc agtcgttttt cgttcgcttt ttcgtttgag agaaacggag tttctcatcg
     1321 gctgttaagc cgatatagcc ctcggcagag cttacagact ttacgcagta taagtctagt
     1381 aagttatacc ttacatggag gtttttccga atttagcttg tgattctcgc aataatttta
     1441 acgaaaggaa gtacacagtt atggcctata tggtggcacg aacacaaaag cataaagttg
     1501 ggtcgttaaa tggacttcaa aatcatgtag atcgtaaaac gaaaaatcat acgaataaag
     1561 acattgatat tacgaaaagt ggttctgttg caaagttttc caaaaaatct attttagtgt
     1621 aaaattgaga aaaaagacag agaggataga gtaatgaatc attttaaagg caaacaattc
     1681 aaaaaatgac gtcattattg tcgctgtt
//
LOCUS       DAFENC010000130         1616 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.141, whole genome shotgun sequence.
ACCESSION   DAFENC010000130
VERSION     DAFENC010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1616
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.141"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            309..1496
                     /locus_tag="LP493_002923"
     CDS             309..1496
                     /locus_tag="LP493_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBL2135008.1"
                     /translation="MYFLGIDIGKRTHVASIMNEEGKVLLKGFSFPNTTEGAESLIER
                     MVDYSGAPSDFVIGMEATGHYWLSIFSYLHESDYLIHVVNPLQTDGWRKGTEIRKRKN
                     DIIDSVLIADLMRYGSFVETVLSDENVFSLKQLSRYRTYLVGTASDFKRKIIAVLDQV
                     FPEYATIFTKQGVFGKASKELLLAFSAPIDLENISSETLAQYLAELSRNRIKAEKADQ
                     LKQAASNSFGVKFAQEAFTFQLRSMIEQLKFIESQIKETEREIKHIMDTLNSVILTIP
                     GIGPINGATILGEIGDIQKFSNPKKLVAYAGIDASVTQSGQYEATHNVMSKRGSPYLR
                     KALFSAALVASQCDPVFSAFYQKKVSEGKHHLTALGAVSRKLCYVIHAILTKNEPYII
                     VSD"
BASE COUNT          477 a          298 c          324 g          517 t
ORIGIN      
        1 gtatattaga gttagggttt taaccttccg gttttgattg gataacccta tgaaccatcg
       61 ttattttaat ttggtattaa ctcatttctt ttgagataat atatttattg gattgagagg
      121 ctaagccgtt ccccccttgg gccattgaac ccgcactcga gagactggct cctctctctg
      181 ataagtggat tgcgtatgag ttagatgttg aaagtcctta ctttactccg tatctcgtac
      241 aaggtagtga cgcttttcag ttgagtggat ttcaatccaa aattcttttt ttgaaaggtc
      301 agatatacat gtacttttta ggcattgata tcggtaaacg cactcacgtt gcttctatca
      361 tgaacgagga aggaaaggta ttactaaaag gtttttcatt tcctaacacc actgaaggag
      421 cagagtcatt aattgagcga atggtcgact attccggagc acccagtgac tttgttatag
      481 ggatggaagc cacggggcac tattggctgt ccatcttttc ataccttcac gaatcagatt
      541 atttgattca cgttgtgaat ccccttcaaa cagacggatg gcgtaaaggt acagaaatac
      601 ggaaacgaaa aaacgatatt attgattctg ttttgattgc tgacttaatg cgctatggct
      661 catttgtcga aacggtctta tccgatgaaa atgttttttc tttgaaacaa ctttctcgtt
      721 accgaactta tttagtaggt acagcgagcg acttcaaaag aaaaattata gccgtattgg
      781 atcaagtctt tccagaatac gcgacgattt ttaccaagca gggcgttttc ggaaaagctt
      841 ctaaagagtt attgctggcg tttagtgccc cgatcgactt agaaaacatt tcctcagaaa
      901 ctttggccca atacttagct gagttaagca ggaaccgaat caaggcagaa aaagcggacc
      961 aattgaagca agcagcttct aactcctttg gagtaaaatt tgctcaagaa gcgttcacct
     1021 tccaactacg ttcaatgatt gaacaattaa aattcattga aagccaaata aaggaaacgg
     1081 aaagagaaat caagcacata atggacactt taaattctgt tattctcaca attcctggaa
     1141 ttggtcctat aaacggtgcg actattcttg gtgagatcgg agatattcaa aaattttcta
     1201 acccgaaaaa actcgttgct tacgctggga tagacgcttc cgtgacacaa tcagggcaat
     1261 atgaggcaac gcataatgtt atgagtaaac gagggtctcc atatttgcga aaagccttgt
     1321 tttcggcggc tttagtagct tctcaatgtg atcctgtttt tagtgcgttt taccagaaaa
     1381 aagtttccga aggaaaacat catctaactg ccttaggtgc ggtttctcgt aagctttgtt
     1441 acgtgattca tgctattttg actaaaaacg agccttatat aattgtttct gattagctat
     1501 tgaacattca aaaaaactaa tggtaagaag cttatttgtt gtaccctttt ttcggaatta
     1561 tctgttataa aatatttttt gatttggcta atttttactt gactctatat agttag
//
LOCUS       DAFENC010000131         1595 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.142, whole genome shotgun sequence.
ACCESSION   DAFENC010000131
VERSION     DAFENC010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1595
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.142"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..447)
                     /locus_tag="LP493_002924"
     CDS             complement(<1..447)
                     /locus_tag="LP493_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HBL2135009.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERSVS
                     CGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDR"
     gene            633..1568
                     /locus_tag="LP493_002925"
     CDS             633..1568
                     /locus_tag="LP493_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBL2135010.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT          502 a          269 c          331 g          493 t
ORIGIN      
        1 tcgatcatgg attgagcgct gatactgttg ttttccccgt ttttcctgat ggccattggg
       61 ttttctttta cctttcatcg gtagtgtgtc aatatcaaat attcctttag aaaataaacg
      121 ataaagtgtt ctcataccgc atgaaacaga cctttctttt cgcccgataa tgacgtcagg
      181 cgtccaacca agagtgactt tctctttaat gtaatctact tcatgagcag gtaattgaat
      241 gacttttcta ccacattttt tcttattttc tttatactgg tgccaataat caagagcagt
      301 cttgccttgc ttgaacttat tgactacatt ataaatagtt tgtatagcac gtcccattcg
      361 gttagcgatt tcaaccggct tattatgttg aagataatat gattctatca ttgtcagttc
      421 gtctatggta agatgtttgt aggtcattta tggttacact cctttgtttt ctttcgtcgg
      481 aaatacaatt tgagtgtacc ataaatgcct ttttattttt ctaacttaat tttacaattc
      541 gcgggttata aaaatgaaca ttgcatagta gagattcttt gattatacta attcaaggtt
      601 atatgaaaaa agagaaatga gatggatgat ttatgaaact ttggatgaaa atccttttag
      661 gcgtcgcttt agctctgatt gttgcgttag tgtttgcagg gaattatttt tataattatg
      721 ctgttgtgcc ttctgagaaa gactttttag acgaagatac acctggtaca acacagacat
      781 ccaaagaaac ggatgcacat aaatggttta gttcaaaaga aaaccgaagc gattggacca
      841 tcacttcaaa agacggtctg aaattatcag cgatttatct tcctgctgaa acgaaaagtg
      901 aaaaaacagc tcttgtggct catggctata tgggaaacgc tgaaacgatg accaattacg
      961 caaagatgtt tcatgatatg ggttacaatg tccttgttcc tgatgcaaga ggacatggaa
     1021 aaagcgaagg ggattacatt ggatttggat ggccagagcg taaagactat gtacagtgga
     1081 taaacaaagt gctagaaaac aatggaaaat cgcaagaaat cgttctatac ggtgtcagca
     1141 tgggagcagc aacagttatg atgactagcg gagaaaaact accagataat gtgaaagcaa
     1201 tcattgaaga ttgcggttat tcttccgttc atgatgagct tgcttatcag ctagacgata
     1261 tgtttagtct tccagcattt ccgcttatgc aagtaacgag tctagtgaca aaagtccgtg
     1321 ctggctactt tttcggtgaa gcaaatgcag tggaacaatt gaagaaaaac cagcgcccaa
     1381 tgctctttat acatggagac gaagatacat ttgtaccatt tgaaatgtta gataaggtct
     1441 atcgtgcaac gaagggacca aaagaaaagt atgttgtaaa aggagccgag catgcggaag
     1501 catacaagac agatcctgaa aaatatcagc aagtagtcca acaattttta agccaatatg
     1561 ttcattgaac gagtttaaaa gtaggggatg aaaag
//
LOCUS       DAFENC010000132         1559 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.143, whole genome shotgun sequence.
ACCESSION   DAFENC010000132
VERSION     DAFENC010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1559
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.143"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            109..1278
                     /locus_tag="LP493_002926"
     CDS             109..1278
                     /locus_tag="LP493_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBL2135011.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     FMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAPTESAYIWKEVLQDLRKRG
                     LEEVLLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIAHKVRVRGRKEICEDFKLV
                     YQANSKEEALDHIDFMTRKWKKQYPRVVNLLLNPALLTFYNFPHAIRRTIYSTNLIEG
                     FNKQLKRYTRRKEQFPNEESLERFFISQFNQYNQKFLGRIHKGFKEIQDTLESMI"
BASE COUNT          555 a          251 c          258 g          495 t
ORIGIN      
        1 ttatgatagc gtaaaatatt ttgtgtaaat agaaatttag ggtagaaaaa aaagtccatt
       61 ctgtaaaatt aaagttacca cacagaaatt ttataggagg actttctcat gactaaattt
      121 actatagaaa ttatgcaaac actactcaat aaaggggatt tagatgaatt atttcaggat
      181 catttagagc gagcgattaa ttcacttcta caagcagagc taactgcttt tttagattac
      241 gaaaaatatg atcgaaatgg attcaattca ggaaattccc gtaacgggaa ttattcacgt
      301 acatttaaaa cagaatatgg cgagttgaat ttaactattc ctagagatcg gaatggcgaa
      361 ttttctcaac aaacactacc agcatataag cgaaccaatg attcattaga aacgaccatt
      421 atccaattat ttcaaaaagg cattactatg gctgaaatct ccaaattaat tgaaaaaatg
      481 tatggtcacc actatacgcc acaaacaatc tccaacatga gtaaattggt ggctgaagat
      541 gttttagctt ttaaagaaag aacgttagaa gccaattatt ccgttatatt tatggatgcg
      601 acgcatatcc ctgtgaagcg acagactgtt tcgaaggaag cagtgtatat tacgattggt
      661 attcgtttgg atggaaccaa agaagttctt gggtttacta ttgccccaac tgagtctgct
      721 tatatttgga aagaagttct tcaagatctt agaaaacgtg ggttagaaga agttttatta
      781 gtagtgacag acggattaag ctgtattgaa gaaagtatcc atagtgtgta tccgaatgcc
      841 caatttcaac aatgttgtgt gcatgtatct agaaatatcg ctcataaagt tcgtgttcga
      901 ggtcgaaaag aaatttgtga ggatttcaaa ttggtttacc aagcgaattc aaaagaagag
      961 gcattggatc acatcgactt tatgactagg aaatggaaaa agcagtatcc aagagtcgtc
     1021 aatttactct tgaatcctgc cctattaacc ttttataatt tccctcacgc catcagacga
     1081 acaatttatt cgacgaacct gattgaaggc tttaataagc agctaaaacg atatactcga
     1141 agaaaagaac aattccctaa tgaagaatct ctagagagat tcttcatttc tcaatttaat
     1201 caatataacc aaaaattttt aggtagaatt cacaagggat ttaaagaaat tcaggataca
     1261 ttagagtcga tgatttaact gtaattaaca gaatggattt tccatttaca tataattctt
     1321 gacgctacca taatctaaat aaccatcata ttcatctact acttatataa ttgagtttta
     1381 ttaaactttt taagtttcta ttctatcaaa tatttaaaca atctctgcat ccgaaaagac
     1441 tacctcgtat agttttacta acaatatttt tattagcgtg ttcaaatcct gatttcttgt
     1501 atcaattatt ttctgttcac tttcaataag aaaaaagtct ttacttccat ggataataa
//
LOCUS       DAFENC010000133         1424 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.146, whole genome shotgun sequence.
ACCESSION   DAFENC010000133
VERSION     DAFENC010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.146"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(150..1337)
                     /locus_tag="LP493_002927"
     CDS             complement(150..1337)
                     /locus_tag="LP493_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HBL2135012.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DAFENC010000134         1423 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.147, whole genome shotgun sequence.
ACCESSION   DAFENC010000134
VERSION     DAFENC010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1423
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.147"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            98..1390
                     /locus_tag="LP493_002928"
     CDS             98..1390
                     /locus_tag="LP493_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBL2135013.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQ
                     LYQDFLYAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPL
                     ECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
BASE COUNT          463 a          292 c          257 g          411 t
ORIGIN      
        1 acaccagcat cttttttatt ttccaaaaca tatagaaaag acaccttgaa atcctttaga
       61 attaatttgg cgaaccaacc caaaaggagg aatcaagatg tcttacactc accttatcaa
      121 agaaacatta gatattctag acttatcagt tacttttaac gaaaattgtc tcacaaaaga
      181 aaaatacaaa gggcaaatct gtcatattta tcgtggaaac ttgatttata cagcccaaga
      241 atgcatccac tgtaaacacc agattgcttc agatattgtg cgttggggta caacaaccgt
      301 ccggttgtta atgaacgatg tttctgaata ccgtacctac ctcgaattga aaaagcaacg
      361 cttcaaatgc aaagcttgtc agcggacctt tgtcgcagat acttctgttg cgaaaaaaca
      421 ttgtttcatc agtgagaaag tccgctggtc tgtcgtgact cgtctgaaaa aaaatacctc
      481 aatgacagag atcgccgctc agaaaaatct atcggtctct tctgtttacc gtattatgaa
      541 gcgattttat cgtccgttga atccttttcg gacaccgtta cctaaggtac tttgttttga
      601 tgaattcaaa tcagttcggg gtgtttcagg tgctatgagt ttcatcatga tggatggaca
      661 aacacagcgc ttattggaca ttgtcgagaa ccgacaactg ccttttttaa aacgttattt
      721 tagtcatttt tcacgagaaa ttcgtgaagc ggtcgaatgg atcgtgattg atatgtacgc
      781 tccttatgta tcgctcgtta aaaagctgtt tccaaaagca cagctgatta ttgaccggtt
      841 tcacatcgtc caacatattg gtcgtacctt tcgcaatcat cgaatcaaag aaacgaacca
      901 actattaaaa agcaaagaac aaaaacacta tcaattaggt aagcaattaa aaagatactg
      961 gaaacttctt caaaaagatg aacgcaagct tgattatact cgacgccttt ggcgacctgg
     1021 cttcaaagct catttaacag agaccgatat tgtggatcgc ttactgaaag ggagccctgc
     1081 tttgcgtgta ggctatcagt tatatcaaga ctttctttac gctgtaaagg aacgagacta
     1141 cgtatcgttt gaagaactac ttaccaataa tatcatgctt cccgaaggct atcagacgac
     1201 cttgagaacg ttccagaaat ttctgccaca aatcaaaaat gctttacaac aaagttattc
     1261 aaatggccca cttgaatgtc tgaacaacca tatcaaagtg ttaaaacgaa atgcatatgg
     1321 ctttcgtagc ttttataatt tcaaattgcg catcatgatt cgtcatggca acgcattgat
     1381 tttcaactaa aaaagatcaa gaggaactga tccacttgat ctc
//
LOCUS       DAFENC010000135         1371 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.149, whole genome shotgun sequence.
ACCESSION   DAFENC010000135
VERSION     DAFENC010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1371
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.149"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            268..810
                     /locus_tag="LP493_002929"
     CDS             268..810
                     /locus_tag="LP493_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2135014.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            966..1340
                     /locus_tag="LP493_002930"
     CDS             966..1340
                     /locus_tag="LP493_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HBL2135015.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMPDVEWQHFF"
BASE COUNT          544 a          162 c          262 g          403 t
ORIGIN      
        1 cctccagtgt gttttttatt attctacaca ccttattttt tctgtctagt ctagtgtagc
       61 cgattcaaat tgatgaagca gatcccaaag ggctgcttca tcaatttttt cgtaagtgtc
      121 cgtacactta ctgtgcttgc tcatatatta atcgatcata tactaatcgt gtaagaacaa
      181 ctttaagcat aatacttata ttgttatacc atagtttgga aaaataaaaa attatatttc
      241 atcaacgttt cataaaaggt gtgtagaatg ttattgaaag tagctataaa atgctattgt
      301 gtaaaaaata aaggaggaat aatttatgaa aaaatagtac caagaggagc atgcctatta
      361 cttgcattat gtttgagctt aagcgcagtt gggtgtcaaa aaagtaatga aaacaataaa
      421 ataaaagaag gacaatccat aagttctgaa gaggaaggca tgtcaattaa tgcaaatggc
      481 aaaaatgaaa cttttaagcc atcagattat acattggagg caaagaaaga atatgtttat
      541 gaatatttag ggcttaaatt taaactctca gacaaattta gaaattatat agctgataaa
      601 aagatagcga tgttagatga tcaaagtcct atagataaag aactaaagta tgctattttg
      661 acatttgaga aaatgacaga agaacaaaag aatgcagtta tagaaaagat gggcgatgga
      721 tataaaaatt ggcaaaatga gcttgaaaga attgggacta ttggtatatt tgaaaaaaat
      781 acatcagaag aaaaaaatct aaaattataa aatgtgatac tcatactaaa ataggagttt
      841 caagtgatgg aaaatacgat tgctatttaa gcacaaatag cggagctgaa agtaatcttc
      901 tggatgaatt aaaaagaact gagattcaaa ttatagataa aaaagaacgt cctaaaaatg
      961 gttttgtgct atcagaaaaa actgatttag aaaatacaga agcatttaac aaagaatcgg
     1021 ttaaagattt acgtaaacta ccaacaaagg acataaatgg caaggatttt acaagtaaag
     1081 attttgagaa gtatgatctt actatggtaa atgtatttgc aacttggtgt acagcttgtg
     1141 taaaggaaat tcctgatttg gttgaggttc agaatgaaat gaaaagcaag ggtgtaaata
     1201 tcgttggagt tgttacagat cctgttgatg ataacggtga aaacaaggaa gcaattgaaa
     1261 agtcaaagtt aatacatgaa aagacaaagg cttcatatcc tttcttaatg ccagatgtgg
     1321 aatggcaaca ctttttttga caaaaattat aaggtgttgt gaatgctgcg g
//
LOCUS       DAFENC010000136         1364 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.150, whole genome shotgun sequence.
ACCESSION   DAFENC010000136
VERSION     DAFENC010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1364
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.150"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            82..>1364
                     /locus_tag="LP493_002931"
     CDS             82..>1364
                     /locus_tag="LP493_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HBL2135016.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQL"
BASE COUNT          465 a          262 c          257 g          380 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaatcaat taat
//
LOCUS       DAFENC010000137         1355 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.151, whole genome shotgun sequence.
ACCESSION   DAFENC010000137
VERSION     DAFENC010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1355
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.151"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..1355
                     /locus_tag="LP493_002932"
     rRNA            <1..1355
                     /locus_tag="LP493_002932"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          362 a          295 c          415 g          283 t
ORIGIN      
        1 caagctgtga tggggaggga aataatagta ccgaagttcc tgatgtcaca ctgccgagaa
       61 aagcttctag tgagaaaaca gcggcccgta ccgcaaaccg acacaggtag tcgaggagag
      121 aatcctaagg tgagcgagag aactctcgtt aaggaactcg gcaaaatgac cccgtaactt
      181 cgggagaagg ggtgctgatc atacgatcag ccgcagtgaa taggcccaag cgactgttta
      241 tcaaaaacac aggtctctgc aaaatcgtaa gatgaagtat aggggctgac gcctgcccgg
      301 tgctggaagg ttaagaggag tgcttagcgc aagcgaaggt acgaattgaa gccccagtaa
      361 acggcggccg taactataac ggtcctaagg tagcgaaatt ccttgtcggg taagttccga
      421 cccgcacgaa aggcgtaacg atttgggcac tgtctcaacg agagactcgg tgaaatttta
      481 gtacctgtga agatgcaggt tacccgcgac aggacggaaa gaccccatgg agctttactg
      541 tagtttgata ttgagtgtct gtaccgcatg tacaggatag gtaggagccg tagaaatcgg
      601 aacgctagtt tcgatggagg cgctggtggg atactacccc tgcgttatgg ccactctaac
      661 ccgcaccact aatcgtggtg ggagacagtg tcagatgggc agtttgactg gggcggtcgc
      721 ctcctaaaag gtaacggagg cgcccaaagg ttccctcaga atggttggaa atcattcgaa
      781 gagtgtaaag gcagaaggga gcttgactgc gagaccaaca agtcgagcag ggacgaaagt
      841 cgggcttagt gatccggtgg ttccgcatgg aagggccatc gctcaacgga taaaagctac
      901 cctggggata acaggcttat ctcccccaag agtccacatc gacggggagg tttggcacct
      961 cgatgtcggc tcgtcgcatc ctggggctgt agtcggtccc aagggttggg ctgttcgccc
     1021 attaaagcgg cacgcgagct gggttcagaa cgtcgtgaga cagttcggtc cctatccgtc
     1081 gcgggcgttg gaaatttgag aggagctgtc cttagtacga gaggaccggg atggacttac
     1141 cgctggtgta ccagttgttc tgccaagggc attgctgggt agctatgtag ggaagggata
     1201 aacgctgaaa gcatctaagt gtgaagccca cctcaagatg agatttccca tttctttaag
     1261 aaagtaagat ccctgagaga tgatcaggta gataggtcag gagtggaagt acagtgatgt
     1321 atggagcgga ctgatactaa tcgatcgagg actta
//
LOCUS       DAFENC010000138         1294 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.152, whole genome shotgun sequence.
ACCESSION   DAFENC010000138
VERSION     DAFENC010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.152"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            225..1100
                     /locus_tag="LP493_002933"
                     /note="aph(2'')-Ia"
     CDS             225..1100
                     /locus_tag="LP493_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021424053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HBL2135017.1"
                     /translation="MKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTN
                     KKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTM
                     SEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEK
                     DYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDF
                     IYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEF
                     IENGRKEIYKRTYKD"
BASE COUNT          552 a          105 c          208 g          429 t
ORIGIN      
        1 caagatatat taaattgatt tttgaatttt tgaaaaaaga aagaaatgct aatgcagtta
       61 ttttagaccc tcataaaaat aatccaagag caataagggc ataccaaaaa tctggtttta
      121 gaattattga agatttgcca gaacatgaat tacacgaggg caaaaaagaa gattgttatt
      181 taatggaata tagatatgat gataatgcca caaatgttaa ggcaatgaaa tatttaattg
      241 agcattactt tgataatttc aaagtagata gtattgaaat aatcggtagt ggttatgata
      301 gtgtggcata tttagttaat aatgaataca tttttaaaac aaaatttagt actaataaga
      361 aaaaaggtta tgcaaaagaa aaagcaatat ataatttttt aaatacaaat ttagaaacta
      421 atgtaaaaat tcctaatatt gaatattcgt atattagtga tgaattatct atactaggtt
      481 ataaagaaat taaaggaact tttttaacac cagaaattta ttctactatg tcagaagaag
      541 aacaaaattt gttaaaacga gatattgcca gttttttaag acaaatgcac ggtttagatt
      601 atacagatat tagtgaatgt actattgata ataaacaaaa tgtattagaa gagtatatat
      661 tgttgcgtga aactatttat aatgatttaa ctgatataga aaaagattat atagaaagtt
      721 ttatggaaag actaaatgca acaacagttt ttgagggtaa aaagtgttta tgccataatg
      781 attttagttg taatcatcta ttgttagatg gcaataatag attaactgga ataattgatt
      841 ttggagattc tggaattata gatgaatatt gtgattttat atacttactt gaagatagtg
      901 aagaagaaat aggaacaaat tttggagaag atatattaag aatgtatgga aatatagata
      961 ttgagaaagc aaaagaatat caagatatag ttgaagaata ttatcctatt gaaactattg
     1021 tttatggaat taaaaatatt aaacaggaat ttatcgaaaa tggtagaaaa gaaatttata
     1081 aaaggactta taaagattga ttatataata tatgaaaagc tattataaaa gacattagta
     1141 ttaaatagtt taaaaaaatg aaaaataata aaggaagtga gtcaattcca gactcctgtg
     1201 taaaatgcta tacaatgttt ttaccatttc tacttatcaa aattgatgta ttttcttgaa
     1261 gaataaatcc attcatcatg taggtccata agaa
//
LOCUS       DAFENC010000139         1278 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.153, whole genome shotgun sequence.
ACCESSION   DAFENC010000139
VERSION     DAFENC010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1278
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.153"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(104..553)
                     /locus_tag="LP493_002934"
                     /pseudo
     CDS             complement(104..553)
                     /locus_tag="LP493_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            897..>1278
                     /locus_tag="LP493_002935"
     CDS             897..>1278
                     /locus_tag="LP493_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2135018.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIK"
BASE COUNT          427 a          202 c          199 g          450 t
ORIGIN      
        1 aaatcagatc cgaggatgct cattgtcaag ggcaatcgta gccataacac cgcagcattc
       61 acaacacctt ataatttttg tcaaaaaaag tgttgccatt ccactttttt aaatatgcgt
      121 tctctgctct taaacgaata acttcttctt caagagactc atctttaagt tttttaggaa
      181 tgtttagctt ggaattcata ctaatttttc tgcccctttt ttggctctca agtgaagaag
      241 caccgccttc ttcatattgc tctatccatt tacttagagt tctatttgaa ccgatattaa
      301 attttttagc agtttcttgg atagaaagac catttgtttc catatattct ataacatcaa
      361 gtttaaattt tgtagtgtag cttttgccac ctccaaccaa gccttcccaa ccatgatagt
      421 tataaatcct tacccaatgt ctaaccagtg tacgatttat ttgatattta tgtgcaagat
      481 atttgtagcc gccttcgtta tttaaatagt ctgaaactac ttttttctta aaaacaaatg
      541 tatatttccg caaaaaaagc acccctttta attagatttc tagtctaact tttggggtgc
      601 acatcatttt tgaggggaag tacatatagt tgttgatata gttgctaata ttgttagcta
      661 atttgttagt aaaactgtat acgaatttag atagtaaaaa aacagtttgt tccttatata
      721 gaggcacttt tactactgat taaatgtcag atatgcttac aaatatactt ataaatatgc
      781 ttacaaaatt agctaatatt tccgttgaca aagctttgtt actattgtta aactaaattg
      841 actagcaaaa gtgaaacata aatttattaa ataaatgtaa aaattaggag aaatcaatgt
      901 cttatagagt acaattaata atttcagaag atgtagaaag tcagcaattt ggcactaatg
      961 ttattaataa agtaattaat ccagctcttt ctattaatgc gcctttaatt cctactgctt
     1021 tatcattttc tgtaacagct gtggtgtctg agatagagga tacagaaaag ataaaaatag
     1081 tagaaattga agttttaaac aagaatgaaa aacaaatttt ttctacgggt gaagtatcgg
     1141 taagcttgcc tcctcaagtt aacgatataa actttaatat aaacgccaga aatgtcttgg
     1201 ttgaagaagc aggagagcat tatgctgttg ttaaatttaa tggaactgag attggaaggc
     1261 aaatctttga tatcaagg
//
LOCUS       DAFENC010000140         1242 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.154, whole genome shotgun sequence.
ACCESSION   DAFENC010000140
VERSION     DAFENC010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1242
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.154"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            33..1211
                     /locus_tag="LP493_002936"
     CDS             33..1211
                     /locus_tag="LP493_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HBL2135019.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDATYIPLKRQTVSKEAIYIAIGIREDGTKEVLSYAIAPTESTYVWNELLQDINSRG
                     VQEVLLFITDGLKGMKDTIHQIYPKAKYQHCCIHVSRNIAHKVRVKDRKEICDDFKAV
                     YQANSKEEANTFLSGMIEKWKKNYPKVTQSLIENQDLLTFYDFPPSIRRTIYSTNLIE
                     SFNKQIKRYSRRKEQFQNEESLERFLVSIFDTYNQKFLNRSHKGFQQVTDTLVSMFTE
                     "
BASE COUNT          456 a          230 c          206 g          350 t
ORIGIN      
        1 gacaaccaat tcacagaaaa gaggacttcc ctatgaatga ttttactaca gaaattgtgc
       61 aaactctagt cactaaaggc gatttaaatg aattattccg ttcgcactta gaaaaagcga
      121 taaacacact cctacggact gaattaacgg cttttttaga ttacgaaaaa tatgatcgca
      181 ctggttttaa ttcaggtaat tcgagaaacg gttcttactt tcgatcaatc aaaaccgaat
      241 atggtgaatt aacattggaa atacctagag atcgtaatgg tgagtttaaa caacaaactt
      301 taccagccta caaaagaaca aacgatacat tggaaaccac tattatccat ttattcgaaa
      361 aaggtgttac gatgtctgaa attgctgatt tgatcgaaaa aatgtacggt catcactata
      421 ctccacaaac catgtccaac atgactaaag ttctgactga agaagtaaat gcctttaaat
      481 ccagagcctt aaatgataag tatgtcgcta tttttatgga cgctacttac attccactaa
      541 aacgtcaaac cgtatccaaa gaagcgattt atattgccat tggtatacga gaagacggca
      601 ctaaagaagt actgagttat gcgattgctc caactgaatc aacatacgtt tggaatgagc
      661 tgctacagga tattaactcc agaggagttc aagaagtctt gctttttatt acggacggct
      721 taaaaggcat gaaagatact atccatcaaa tttatcctaa agcaaaatat cagcattgtt
      781 gtatccatgt atctcgtaac atcgctcata aagtacgtgt caaagaccga aaagaaatct
      841 gtgatgactt taaggctgtt tatcaagcta actcaaaaga agaagcgaat accttcttat
      901 ccggcatgat tgagaaatgg aagaaaaact atcctaaagt gacgcagtca ctcatagaaa
      961 accaagactt attaactttt tatgattttc cacctagcat tcgtagaacc atttactcaa
     1021 ccaatctaat cgagtctttc aataagcaaa ttaaaagata cagccgtaga aaagagcagt
     1081 ttcaaaatga agaatcacta gaacgctttc tagtcagcat ttttgataca tacaatcaaa
     1141 aatttctaaa cagaagccat aaaggttttc aacaggtaac cgatacatta gtttcaatgt
     1201 ttactgagta actaattatt ttgcaggagg acaatttatt ta
//
LOCUS       DAFENC010000141         1194 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.156, whole genome shotgun sequence.
ACCESSION   DAFENC010000141
VERSION     DAFENC010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1194
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.156"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..1076
                     /locus_tag="LP493_002937"
     CDS             <1..1076
                     /locus_tag="LP493_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBL2135020.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          210 g          332 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tctt
//
LOCUS       DAFENC010000142         1159 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.157, whole genome shotgun sequence.
ACCESSION   DAFENC010000142
VERSION     DAFENC010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1159
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.157"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..>1159
                     /locus_tag="LP493_002938"
     CDS             <1..>1159
                     /locus_tag="LP493_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBL2135021.1"
                     /translation="IYFEENCLTKEKYKGQICLIYKGTLLYKPEECSHCLCVVPSRII
                     RWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADTSVAEKHCFISQKVRWSV
                     IARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQTLPKVLCFDEFKSVRSVA
                     SAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREAVQLIVIDMYAPYVSLVK
                     KLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHSQRGLGKKLKRYWKLLQK
                     EEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQLYQDILYAVKKRDQSLF
                     EDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGPLECLNNHIKVL"
BASE COUNT          354 a          229 c          233 g          343 t
ORIGIN      
        1 atctatttcg aggaaaattg tttaactaaa gaaaaataca aagggcaaat ttgcttgatt
       61 tacaaaggaa ctcttctgta caagccagaa gagtgttccc attgtctttg tgtcgtcccc
      121 tctaggatca ttcgttgggg gacgacaacc gttcggttgt tactgaatga tgtgtctgag
      181 tatcgcactt atctggagct gaagaaacaa cgatttaaat gtaagtcttg ccaaagaaca
      241 ttcgtagcgg atacctctgt tgctgaaaaa cactgtttca ttagtcaaaa agttcgttgg
      301 tctgtcattg ctcgcttaaa agagaatact tccatgacgg aaatcgctcg tcagaaaaat
      361 atttccactt cttcggtcta tcgtgtcatg aagcgattct accgcccatt gaatcctttc
      421 aaacagactt tgccaaaggt cttatgcttt gatgaattca aatcggttcg aagtgttgcc
      481 agtgcaatga gttttatcat gatggacgga caaagccatg cattattgga tattgtcgaa
      541 aatcgacgct tgccttattt agaacgctat ttttctcggt tttcattagc gactcgtgaa
      601 gccgttcaat tgattgttat tgatatgtat gcgccttatg tttcgttggt gaaaaagctt
      661 ttcccgaatg ctcagttgat catcgatcgt ttccacatcg tccaacatat tggcagaact
      721 ttcttgaatc atcgagtgaa agaaaccacg gtacgactta aaggaaattc ccactctcaa
      781 cgagggttag ggaaaaaatt gaagcgctat tggaaactcc tacaaaaaga agaagcaaag
      841 ttaaactatg aaaaacgggt ttggcgtgcc agttttaaag attatttgac tgaaagtgag
      901 attgccgatc gactgttagc tgcttgtccc aacttacgcc aaggctatca gttataccaa
      961 gacattcttt atgcggtaaa gaaaagagat cagtcactat ttgaggattg tttaactaga
     1021 gacattagcg gtctgccaga aacctataca accactttac gaacgtttaa aaagtttctg
     1081 ccacagatcc aaaatgcgct tcactacagc tattcaaacg gaccattgga atgcttaaac
     1141 aaccacatca aagtattaa
//
LOCUS       DAFENC010000143         1121 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.158, whole genome shotgun sequence.
ACCESSION   DAFENC010000143
VERSION     DAFENC010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1121)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1121)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1121
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.158"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            2..>1121
                     /locus_tag="LP493_002939"
     rRNA            2..>1121
                     /locus_tag="LP493_002939"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          343 a          222 c          327 g          229 t
ORIGIN      
        1 ataagggcgc acggtggatg ccttggcact aggagccgat gaaggacggg actaacaccg
       61 atatgctttg gggagctgta cgtaagctat gatccagaga tttccgaatg ggggaaccca
      121 acatctttaa taggatgtta cgattgtgtg aatacatagc acattcgagg tagacgcaga
      181 gaactgaaac atctaagtac ctgcaggaag agaaagaaaa ttcgattccc tgagtagcgg
      241 cgagcgaaac gggaaaagcc caaaccagca agcttgcttg ttggggttgt aggactccaa
      301 tatggtagtt ctttcagata gtcgaatgac ttggaaaagt cagtcaaaga gggtaaaaac
      361 cccgtagacg aaatgtggaa gacacctagg aggatcctga gtacggcgga acacgagaaa
      421 ttccgtcgga atccgggagg accatctccc aaggctaaat actccctagt gaccgatagt
      481 gaaccagtac cgtgagggaa aggtgaaaag caccccggaa ggggagtgaa atagaacctg
      541 aaaccgtgtg cctacaacaa gtcaaagccc gttaatgggt gatggcgtgc cttttgtaga
      601 atgaaccggc gagttacgat tgcatgcgag gttaagttga agagacggag ccgcagcgaa
      661 agcgagtctg aatagggcgt ttgagtatgt agtcgtagac ccgaaaccat gtgatctacc
      721 catgtccagg ttgaaggtgc ggtaaaacgc actggaggac cgaacccacg tacgttgaaa
      781 agtgcgggga tgaggtgtgg gtagcggaga aattccaaac gaacttggag atagctggtt
      841 ctctccgaaa tagctttagg gctagcctcg gaattgagaa tgatggaggt agagcactgt
      901 ttggactagg ggcccatctc gggttaccga attcagataa actccgaatg ccattcattc
      961 atatccggga gtcagactgt gagtgataag atccatagtc gaaagggaaa cagcccagac
     1021 caccagctaa ggtcccaaaa tatatgttaa gtggaaaagg atgtggggtt gcacagacaa
     1081 ctaggatgtt ggcttagaag cagccaccat ttaaagagtg c
//
LOCUS       DAFENC010000144         1121 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.159, whole genome shotgun sequence.
ACCESSION   DAFENC010000144
VERSION     DAFENC010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1121)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1121)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1121
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.159"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            50..1045
                     /locus_tag="LP493_002940"
                     /pseudo
     CDS             50..1045
                     /locus_tag="LP493_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305143.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
BASE COUNT          455 a          145 c          187 g          334 t
ORIGIN      
        1 ttcaaaaaaa aaccaaccga aagatataaa agatattgta gatacacgaa tgtataaaga
       61 acgtgatgac ttaaactata cgcttattat caataaagat ggaaactatt catggcgtcc
      121 tctcgttcta ctacatccta ttctatatgt agatttggtt aattgtctca ctaaagaaga
      181 ccattgggag gagttaaaaa agaggtttag tgaatttaaa aaagataaaa atattaactg
      241 ttattctata cctgttgaag cttccaaagg ttcaaaaagg acagatcttg gtgaaacaat
      301 actaaactgg tgggaatatt ttgaacaaaa aagcttagct cagaatatta aataccaata
      361 ttgcatgttt actgacatcg ctgattgtta tccatcaatt tatactcact ctataacatg
      421 ggccatgtat ggtaaagaaa aagttaaaaa tgatgaaaat aagtgttcgg gctcacttgg
      481 cgataaaata gataaaaaaa tatctggaat gcaacacaat caaacaaatg gtatccctca
      541 gggttccgtt cttatggatt ttgtagcaga gatcgttcta gggtatgttg atttgagatt
      601 atcgaaagaa ttaaaaaaat tagaaaattt aaaagattac aaagtactca gatatagaga
      661 tgattataga atattttcaa ataatcgtaa tgatttggaa caaattatga aagtgttatc
      721 agaagtctta tatgatttaa attttaagtt aaattctagt aaaacaaaat tatcagatga
      781 tattatcata gattctatca aaaaagataa gctctattgg gaagaaatta aggcaagtat
      841 aagaatgaat gccacaaact tagatggtga tagagaaatt cgttatagta taaatttaca
      901 aaaacattta ttggaaataa aaaagttagc agataagcat cctaattcag gccaattgaa
      961 aaaagcactt tctgagttta ataaagaacg cattattaaa atcacttcaa agccgaacga
     1021 tcttttacca cttattggta tccttgaatc ggctacacta gactagacag aaaaaataag
     1081 gtgtgtagaa taataaaaaa cacactggag gatttttcat g
//
LOCUS       DAFENC010000145         1106 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.160, whole genome shotgun sequence.
ACCESSION   DAFENC010000145
VERSION     DAFENC010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1106
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.160"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..1087
                     /locus_tag="LP493_002941"
     CDS             <1..1087
                     /locus_tag="LP493_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBL2135022.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT          403 a          192 c          214 g          297 t
ORIGIN      
        1 agatatcaat gatgatggct caagaaaaaa agtggagaaa gttggcggag acacccgacc
       61 agaggccgaa gctgctttac gaaaagtttt atcagatatt gacgaaacag gacaatactt
      121 tttaggtacg gatactcgag taaaacaata ccttgatttt tggatggagg aatacgttaa
      181 actaaatcta aaatacaata cctatgaaaa ctaccgattt accatcaaaa atcatataaa
      241 cggttattta ggaaagaaaa aacttacgga tctctcccct gctcttttac aaaatttcat
      301 caatgctgaa tttaaaaagg gttactcgaa gaaaacaatg actattactc actctgtcct
      361 taagaatgcg ctgaatatgg cggtttatcc ttggggatta atcaagcaaa atcctatgct
      421 gtatgtaaaa ataccaaaat atgaagcacg accaacgact aaaaaagatc taaaaatcat
      481 ttctcttgag gactttgatc atatgctaga aattactcct gaaggacatc ctttctatat
      541 tcctttgaat attggatttt atacgggaat gcgcgttggc gaagtttgtg gtctgacgtg
      601 ggatgatgtc gatttttcaa atggaacaat tactgtagag aaacaaatgg taaagaatga
      661 cggcgcatgg gtatatggta cgccaaagac aagcagttcc aatcgaacga tttttattgg
      721 acaaaccttg ctagcaattc tgaaaaaaca taagaaacaa caattagaaa atcgaatgaa
      781 gtatggaaag ctctacattg attcaaatgc agtatgtacg aaggaagacg gtgagctagt
      841 tacgccaagt gtagtgaaat ggaatactag gaggatatcg aatgcactct ccctctcttt
      901 taacttccat tctctcagac atactcatgc tacacttctt ctcgaaaatg gcgcaaaaat
      961 gaaagaaatc tctgaacgat tgggccacag cagaatttca attacgatgg atacttactc
     1021 gcatgtaaca gataagatga gaaatgaaac ggtcgatatc atggaaaatc ttagaaagaa
     1081 ttcttgattt ttgccaccga aaaaaa
//
LOCUS       DAFENC010000146         1061 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.163, whole genome shotgun sequence.
ACCESSION   DAFENC010000146
VERSION     DAFENC010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1061
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.163"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(36..992)
                     /locus_tag="LP493_002942"
     CDS             complement(36..992)
                     /locus_tag="LP493_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2135023.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          346 a          177 c          160 g          378 t
ORIGIN      
        1 tagaaaaagc agtcggactt tctaaaagaa gttcactatt cgatcctgtc gatgatttct
       61 tcaggaaaat cgtctatttg cttgtcaatt ttgctgtctt tgtatttctc ttcttggata
      121 gtcaacaaaa tctttgtaag attcccccag tctactgctc ttggcggatc gagccaaacc
      181 actacttgag atgcactttc ttcatataga ttattcctat tcgtgattat aacatccggg
      241 aactcaggct ttcctgcctc tatcacttcc gtgttcagat taatgtacaa gcttaaattt
      301 ttcttgataa attgattata ggcagcacca taagaaaaat cgatgatgat ctttactggt
      361 tcagaaatca gttgaatggg tatgtgattg atcaataata ataaataact gaaaaaaaga
      421 aaaaatttat cttgaagcaa ctctttgcgt tttgacgtta gatcatttat atactctatc
      481 aaatagcaat aaaatgctgg atagttttct ctaaaaaaag aaacatcaag tggaaattca
      541 tcagctttat taatagtgta atgcaaaagt ttaaaatgta ttttggttaa ctctcttcgg
      601 atcaattggc tcgtctcttc tcgcaacaga ttaaactgat tttcaaaact ttcaatgaat
      661 cgttcattca accattcgat tgtttcatct tcattttttc tcaagtattt ttgatccaat
      721 ttatcatgaa gataaagcca agagagtgtc ttattgataa aaataacgga tttttctcct
      781 aatactcctt ttaagtggta aaatcctata tccgaaaaaa atagcgactg attgctagca
      841 atatctaaag aatcagcttg ttcagccaac aggttgattg ctaaaaagtg gaataatttc
      901 tttttttcat aagcagacag aggataatac tgttttaaat cttttaacat tttttctgtt
      961 tttataatta taggtagcgt atacaattcc acaaaactta tctctgttga gttaaaaaga
     1021 ttatataaaa aaagccgaat gtttttagga ttccctgtca a
//
LOCUS       DAFENC010000147         1052 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.164, whole genome shotgun sequence.
ACCESSION   DAFENC010000147
VERSION     DAFENC010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1052
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.164"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="LP493_002943"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="LP493_002943"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HBL2135024.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          377 a          132 c          182 g          361 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaagct aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgacga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgtaggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaacatttt tt
//
LOCUS       DAFENC010000148         1020 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.165, whole genome shotgun sequence.
ACCESSION   DAFENC010000148
VERSION     DAFENC010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1020)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1020)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1020
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.165"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            3..533
                     /gene="sat4"
                     /locus_tag="LP493_002944"
     CDS             3..533
                     /gene="sat4"
                     /locus_tag="LP493_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HBL2135025.1"
                     /translation="MKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEAPYLK
                     SYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDIAVCK
                     DFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDTMLYA
                     NFENNFEKAVFWYLRF"
     gene            626..>1020
                     /locus_tag="LP493_002945"
     CDS             626..>1020
                     /locus_tag="LP493_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APH(3') family aminoglycoside
                     O-phosphotransferase"
                     /protein_id="HBL2135026.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCP"
BASE COUNT          356 a          168 c          242 g          254 t
ORIGIN      
        1 aaatgaaagc agggcacctg aaagatatcg ataaacccag cgaaccattt gaggtgatag
       61 gtaagattat accgaggtat gaaaacgaga attggacctt tacagaatta ctctatgaag
      121 cgccatattt aaaaagctac caagacgaag aggatgaaga ggatgaggag gcagattgcc
      181 ttgaatatat tgacaatact gataagataa tatatcttta ctaccaagac gataaatgcg
      241 tcggaaaagt taaactgcga aaaaattgga accggtacgc ttatatagaa gatatcgccg
      301 tatgtaagga tttcaggggg caaggcatag gcagcgcgct tatcaatata tctatagaat
      361 gggcaaagca taaaaacttg catggactaa tgcttgaaac ccaggacaat aaccttatag
      421 cttgtaaatt ctatcataat tgtggtttca aaatcggctc cgtcgatact atgttatacg
      481 ccaactttga aaacaacttt gaaaaagctg ttttctggta tttaaggttt tagaatgcaa
      541 ggaacagtga attggagttc gtcttgttat aattagcttc ttggggtatc tttaaatact
      601 gtagaaaaga ggaaggaaat aataaatggc taaaatgaga atatcaccgg aattgaaaaa
      661 actgatcgaa aaataccgct gcgtaaaaga tacggaagga atgtctcctg ctaaggtata
      721 taagctggtg ggagaaaatg aaaacctata tttaaaaatg acggacagcc ggtataaagg
      781 gaccacctat gatgtggaac gggaaaagga catgatgcta tggctggaag gaaagctgcc
      841 tgttccaaag gtcctgcact ttgaacggca tgatggctgg agcaatctgc tcatgagtga
      901 ggccgatggc gtcctttgct cggaagagta tgaagatgaa caaagccctg aaaagattat
      961 cgagctgtat gcggagtgca tcaggctctt tcactccatc gacatatcgg attgtcccta
//
LOCUS       DAFENC010000149         1003 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.166, whole genome shotgun sequence.
ACCESSION   DAFENC010000149
VERSION     DAFENC010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1003
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.166"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..>1003
                     /locus_tag="LP493_002946"
     CDS             <1..>1003
                     /locus_tag="LP493_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBL2135027.1"
                     /translation="GKKISMILLNRSGNKRTYLRLKKQRYLCRACKKYFTARTYLVTP
                     FCFISKQIHYKILEELTERQSIKAIGKHCDVSVTTVQRTLSALSSDIRQNLEYLPRCL
                     LFDEFRSLSTWHGKFSFSCMDGETGKLFEILPSRRKKDLVAFFMRFSLKARLGVHYIV
                     TDMNAPYFSLVKECFPNAQVIVDRFHIVQHLNRFFDAVRKRVMKTLDQKDPIQAKQYR
                     QLKSLFKLLLKSEDRLDYNTLTKRRNFNWRLLTETEVVDRLLKISPELKTAYRYYQDL
                     LTAYQEKDPDTFFQLLRAMPGEVPLELHHIKKAFFKYEKGIRLALLKKYSNARLENLH
                     "
BASE COUNT          300 a          209 c          191 g          303 t
ORIGIN      
        1 tggcaagaag atctctatga ttctcctgaa tcgtagcggt aataaacgga cctatcttcg
       61 gttgaagaaa cagcgatacc tctgccgagc atgtaaaaaa tattttaccg ctcggacgta
      121 tctcgttacc ccattctgct ttatttctaa gcagattcat tacaagatct tagaagaatt
      181 gacagagcgt caatctataa aagcaattgg taaacattgc gatgtttctg tgacaactgt
      241 tcagcggaca ttgtccgcct tgtcatcaga tatccgtcag aatcttgagt atttacctcg
      301 gtgtctatta ttcgatgagt ttcgttctct ttctacatgg cacggtaaat tttctttttc
      361 ttgtatggac ggtgagaccg ggaaactgtt tgagatctta cctagccgcc gtaaaaaaga
      421 tctcgttgct tttttcatgc gtttttctct caaagcgagg ttgggtgtac attacatcgt
      481 aacggatatg aacgctcctt atttctcact agttaaagag tgttttccaa atgcacaagt
      541 gatcgtcgat cggtttcaca ttgttcaaca tctgaaccgc ttcttcgatg cggttcgaaa
      601 acgtgtgatg aaaacacttg atcaaaaaga cccaatacaa gctaaacagt atcgccaatt
      661 gaaatcctta ttcaaattac ttttaaaatc agaggatcgt ttagattaca atacactaac
      721 gaaaagacgc aatttcaatt ggagactatt gactgaaaca gaagtagttg accgccttct
      781 aaagatttct cctgaactta aaacagctta tcgttactac caagacctgc ttactgcgta
      841 tcaggaaaaa gatccagata cttttttcca gctgcttcga gcaatgcctg gagaagttcc
      901 attggaactg caccatatca aaaaagcctt tttcaaatac gagaaaggga ttcggctggc
      961 attactgaag aagtattcga atgcacgact ggaaaatctc cat
//
LOCUS       DAFENC010000150         1000 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.167, whole genome shotgun sequence.
ACCESSION   DAFENC010000150
VERSION     DAFENC010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.167"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(82..636)
                     /locus_tag="LP493_002947"
     CDS             complement(82..636)
                     /locus_tag="LP493_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL2135028.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADVAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGG"
BASE COUNT          324 a          186 c          107 g          383 t
ORIGIN      
        1 acttccgaaa attcagttat cttcattaat ctcaccttct aagttttcat tatacacaaa
       61 aaatatatcc taatatctca attagcctcc caatttaaaa ccacgtaacg atgcccctat
      121 ttcatcttca gttataccaa tgtacctttt tgtaattgct tgcgagctat gattaaaaat
      181 aaacattaag gtagcaatgt ctctagtttt cttgtagtag tgatacccaa aagtttttct
      241 taatgtatgt gttcctatat catctcttcc taatttttct gctacatctg catatatctg
      301 atagacacga tcccttgtta tatgtcgacc ttgttgccga cttggaaata accaatcatt
      361 ttcttcttta ccttcagtat ataataaaat ctcttctctc aaattatcta taaaaatcgg
      421 ttttcgctta cctgttttat gttcaacaat aataggctta cttttacctc gtatgtctcc
      481 aacttttaat cctataatat ctgacatacg taacccatta ttgattccaa acaaaaataa
      541 aaaactatct ctttctggat tacttgttct tcttagccaa aactgaaaat cttgtatctc
      601 ttcatttgtc cttaacggtt gtacattata gctcactatt gtttcccttc ttaaaaatat
      661 tctgagttca tgattatata tatattttac cataatcatg aacttatata tatactctgt
      721 taaaagtgaa gaaaatcaag gggtttagtt tatgatttta tatcatttca gtaactcaga
      781 atattccgac ttttttgtac aaaaaaatta accttactta tatgaagatt ctaagctctt
      841 atttaaattt tagacgggca gttatccgta gaagttctta gaatagctaa tttacataat
      901 taaattatat gaaatttaag tttgaacaat atactaagaa ctccccttac tataaagtga
      961 aataaattag catatgaata accgtgctac caaacttttc
//
LOCUS       DAFENC010000151         1000 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.168, whole genome shotgun sequence.
ACCESSION   DAFENC010000151
VERSION     DAFENC010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.168"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            369..1000
                     /locus_tag="LP493_002948"
                     /pseudo
     CDS             369..1000
                     /locus_tag="LP493_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          342 a          181 c          183 g          294 t
ORIGIN      
        1 tttcaaagtt agtagagaaa atgtagttat atatttaaat ttttaccaga aagaaatgaa
       61 caccttcaat tatctaaatc tcgaaaatgg ttagatgtaa tcatcaggaa aaacaatctt
      121 aaacgaatta ctattcatgg tcttagacac acacatgcta gcttgctttt agcaagctag
      181 tgcaaatatt aaagatgtgc aagagcgttt aggccactct tctattcaaa tcattatgga
      241 tctatatatt catattacag acaaaagaaa agaagaaacc gtagcgcaat tcgcaaaata
      301 taggctctat aatttatggg actgatgaat caaaattgat tcttcagtcc cattgttatt
      361 ttaggtatat gattcgtaca ttgaaagagt tgaaaaacta tcttccgaag ccgtcaaaaa
      421 ggaccctgcc aaaagtattg atggtggatg aatttcgttc gcacgcttca attgtggata
      481 aaatgagctt tatttgtgcg gatggcgaga ctggaaaact cattgatatt ttgcctacac
      541 gaaaattgtc tcgattaaca cactatttta gtcgctgtgc aaatcctgaa gcggtggaat
      601 atttagtgac agatatgaac gccgcctact tccaactgac aaaacgtgtc ttaccaaatg
      661 cgaaagtcgt cattgattgt tttcatatca tcaaacattt gaatcaggcg ttcaatgatt
      721 ttcgtgtaca agaaatgaaa agattacacc agttagggca acgacgggaa gccgagaaag
      781 tgaaaaagaa ctggcgcttt cttctaaaaa accgtcaaaa aatcaatcac tatgattaca
      841 aaacatggcg cagttttcgt gcacctaaat acccgctact cactgaagca atgatgattg
      901 atcgattgct ggcattttca acgcctttaa aggacgccta tacttttttc catgagctga
      961 ccgaagcctt tagagacaag gaatcagact tattttttac
//
LOCUS       DAFENC010000152          991 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.169, whole genome shotgun sequence.
ACCESSION   DAFENC010000152
VERSION     DAFENC010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..991
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.169"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(21..94)
                     /locus_tag="LP493_002949"
     tRNA            complement(21..94)
                     /locus_tag="LP493_002949"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(58..60),aa:Ile,seq:cat)
     gene            complement(108..181)
                     /locus_tag="LP493_002950"
     tRNA            complement(108..181)
                     /locus_tag="LP493_002950"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(145..147),aa:Met,seq:cat)
     gene            complement(209..281)
                     /locus_tag="LP493_002951"
     tRNA            complement(209..281)
                     /locus_tag="LP493_002951"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(246..248),aa:Ala,seq:tgc)
     gene            complement(301..374)
                     /locus_tag="LP493_002952"
     tRNA            complement(301..374)
                     /locus_tag="LP493_002952"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(338..340),aa:Pro,seq:tgg)
     gene            complement(384..457)
                     /locus_tag="LP493_002953"
     tRNA            complement(384..457)
                     /locus_tag="LP493_002953"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(421..423),aa:Arg,seq:acg)
     gene            complement(468..553)
                     /locus_tag="LP493_002954"
     tRNA            complement(468..553)
                     /locus_tag="LP493_002954"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(517..519),aa:Leu,seq:taa)
     gene            complement(570..641)
                     /locus_tag="LP493_002955"
     tRNA            complement(570..641)
                     /locus_tag="LP493_002955"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(607..609),aa:Gly,seq:gcc)
     gene            complement(653..725)
                     /locus_tag="LP493_002956"
     tRNA            complement(653..725)
                     /locus_tag="LP493_002956"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(690..692),aa:Thr,seq:tgt)
     gene            complement(743..824)
                     /locus_tag="LP493_002957"
     tRNA            complement(743..824)
                     /locus_tag="LP493_002957"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(788..790),aa:Leu,seq:tag)
     gene            complement(832..904)
                     /locus_tag="LP493_002958"
     tRNA            complement(832..904)
                     /locus_tag="LP493_002958"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(869..871),aa:Lys,seq:ttt)
     gene            complement(908..980)
                     /locus_tag="LP493_002959"
     tRNA            complement(908..980)
                     /locus_tag="LP493_002959"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(945..947),aa:Val,seq:tac)
BASE COUNT          260 a          283 c          235 g          213 t
ORIGIN      
        1 tgaaacttac aacgccacaa tggaccttgt aggactcgaa cctacgaccg gacggttatg
       61 agccgtctgc tctaaccaac tgagctaaag gtccaggctc ttaaaaatcg cggcggaggg
      121 gatcgaaccc ccgacctccc gggtatgaac cggacgctct agccagctga gctacaccgc
      181 gaaaaagata ttcattattt aaatgaaatg gagcctagcg ggatcgaacc gctgacctcc
      241 tgcgtgcaaa gcaggcgctc tcccagctga gctaaggccc cgtgtttaaa tttataatta
      301 tcgggaagac aggattcgaa cctgcgaccc cttggtccca aaccaagtgc tctaccaagc
      361 tgagctactt cccgtttaat taacgcgccc aagaggagtc gaacccctaa ccttttgatc
      421 cgtagtcaaa cactctatcc agttgagcta tgggcgcata tttgaaatgc cgaggaccgg
      481 aatcgaaccg gtacggtgat cactcaccgc aggattttaa gtcctgtgcg tctgccagtt
      541 ccgccacccc ggcgcgattg ctttggcaaa gcggaaaacg gggttcgaac ccgcgacccc
      601 caccttggca aggtggtgct ctaccactga gctatttccg cgtgtttaaa gatgccggct
      661 aaaggacttg aaccctcgac cctctgatta caaatcagat gctctaccaa ctgagctaag
      721 ccggcatgta aaacttaaat tatgcgggtg aagggacttg aacccccacg ccgtaaggcg
      781 ctagatccta aatctagtgc gtctgccaat tccgccacac ccgcaaaaat atgagccgta
      841 cagggctcga acctgtgacc ctctgattaa aagtcagatg ctctaccaac tgagctaacg
      901 gctcatatgg aggttaacgg gatcgaaccg ctgaccctct gcttgtaagg cagatgctct
      961 cccagctgag ctaaacctcc atggataact t
//
LOCUS       DAFENC010000153          983 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.170, whole genome shotgun sequence.
ACCESSION   DAFENC010000153
VERSION     DAFENC010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..983
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.170"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(34..107)
                     /locus_tag="LP493_002960"
     tRNA            complement(34..107)
                     /locus_tag="LP493_002960"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(71..73),aa:Ile,seq:cat)
     gene            complement(662..976)
                     /locus_tag="LP493_002961"
     CDS             complement(662..976)
                     /locus_tag="LP493_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2135029.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT          363 a          154 c          154 g          312 t
ORIGIN      
        1 tctaacacag aacgattcaa ttggctacat taatgtaccc tgtaggactc gaacctacga
       61 ccggacggtt atgagccgtc tgctctgacc aactgagcta agggtagtgg ttgttgccac
      121 ataaagccat aaacaatcaa ccagtagaat gcgtggcaac aaacctgtta tcgcatatct
      181 tggagtgtga ctatttatga gtgatagtga agatatgcgt ctccatatat gtatggttga
      241 gacagataaa catgtatgaa aaacgttgtt aaatcaacgt ttttttattt tggtcaagga
      301 gagaaaagta gagaaataca aaattttttg cattgatttt gcattcaaaa aaacattcaa
      361 acatttagaa atccccaata cgtattcagg aaaatctatt ttaaggttta caaaaagaac
      421 ttttgttcgt acactctttt tgaggtgaac ttttatgctg atggaaggaa aaacacaatt
      481 atggtttaag catgttcctt caaataagtt ttttaattat aaactctaga gaaattaatt
      541 catcctaaca taaaataatt gttcactcaa aagtttttct agaacaatta aaacagcagg
      601 cttcacattc gctatacatt tgtaagaagt aataattcct gtactaaaag gcataattgc
      661 tttaattatt ttttgacttc tcttcaaaca caagaagtag ttgtgtaata attgcagaaa
      721 taaggattcc aataatagat ataaaatttg acatggaaac gtctataaca ttaaaagaat
      781 aaagtgttga agaaagtaaa ctgattgaaa taacccctcc gtaaaaaata gtctgtgaat
      841 atacccactt tttttcagaa gacgtacttc gtttggttct aaaacctatc cctgcatttc
      901 tactcttatc aaaaaaccaa atatttagaa gtaataatat tgctattatt aagataaaat
      961 tactgtaaaa atccaaaagc tat
//
LOCUS       DAFENC010000154          941 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.171, whole genome shotgun sequence.
ACCESSION   DAFENC010000154
VERSION     DAFENC010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 941)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..941
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.171"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            35..769
                     /locus_tag="LP493_002962"
     CDS             35..769
                     /locus_tag="LP493_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL2135030.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            802..>941
                     /locus_tag="LP493_002963"
     CDS             802..>941
                     /locus_tag="LP493_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HBL2135031.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     IT"
BASE COUNT          334 a          130 c          216 g          261 t
ORIGIN      
        1 gagataaata actttttaaa cgaggagagt tcagatgaaa gaaaacaaat atgatgataa
       61 tatatttttt caaaaataca gtcaaatgag tcgctcgcag aaaggactgg ctggtgcggg
      121 agaatgggag actttgaaaa agatgctacc tgattttaag ggtaagcgtg tgcttgattt
      181 aggatgcggc tatggatggc actgtatata tgcgatggaa aacggtgctt cctctgtagt
      241 aggtgttgat atttctcata aaatgctcga agtagcaaaa ggaaaaaccc attttccaca
      301 gattgaatat gaatgctgtg ccatagaaga tgtggatttc ccagaggaga gctttgatgt
      361 aatactaagt tcgcttgcgt ttcattatgt agcagactat gagaatttaa taaaaaagat
      421 atataggatg ctgaaggctg gtggcaattt agtttttaca gttgaacatc ctgtttttac
      481 tgctcatgga acacaagact ggtattataa cgaaaaagga gaaatactgc atttcccggt
      541 ggacaattat tattatgagg gcaaacggac agctatgttt ttggaagaaa aggttacaaa
      601 atatcataga acactgacca catatctaaa tacactgctt tcaaatagtt ttataataaa
      661 tcagattgtg gagccacagc cgccagagaa catgatggat attccgggga tggcggatga
      721 aatgcgacgc ccaatgatgc tgattgtatc ggcaaaaaag aagatgtaat aatatagaaa
      781 aaataaacga ggagtatgta aatgagatca gaaaaagaaa tgatggattt agtactttct
      841 ttagcagaac aggatgaacg tattcgaatt gtgacccttg aggggtcacg cgcaaatatt
      901 aatataccta aagatgaatt tcaggattat gatattacat a
//
LOCUS       DAFENC010000155          928 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.172, whole genome shotgun sequence.
ACCESSION   DAFENC010000155
VERSION     DAFENC010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 928)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 928)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..928
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.172"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(152..523)
                     /locus_tag="LP493_002964"
     CDS             complement(152..523)
                     /locus_tag="LP493_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2135032.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(525..926)
                     /locus_tag="LP493_002965"
     CDS             complement(525..926)
                     /locus_tag="LP493_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2135033.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
BASE COUNT          298 a          160 c          128 g          342 t
ORIGIN      
        1 agggtgtata ctttttgttt gatatcgtga ctgacgtgcc ggacgcacgt agcgatcatc
       61 ggcgttatga ctatataaag tatactttcg ttgatccaga aagatacaaa gattaaataa
      121 aaaaataaca aacaaactcg cttgaaattc attaggtgag tttgtttatt attttttctg
      181 cttctcgatt catcagcgcc atatctgttt tcgtaatggt ttcattagga atatagtcag
      241 cacattttct tttctctaac attctatacc cactattatg tattcctaag gtattcaatt
      301 ccttaactgt tgaaaacaaa ttccaaacgg tttggtggct tccttttccg ctacttccat
      361 tataaataat atcataattt tctttcaaat actcatcaga ttttttaaaa gcactgtagt
      421 atgctcttga aacagcagtt cttctataag attctttaga attatattta tcatctgatt
      481 caatttgttt ggaaatagat aaatattcat taaagtcaaa cattttattc ccccaaagtt
      541 gctactacag atttccccat atatttatag tcagataata cattatcgag agtatccaaa
      601 acatcgtaat ctgaggaaaa caattcagat gttgttttga taacaaagaa atacaagttt
      661 aaatcttcat catattttat attgatttca gcttttcttt ttaaaaccgt atttatcaca
      721 tcaaaaattt tgccatcatt acttgaaatt gtgttaatct cattttttgt agtaattaca
      781 agttgattat catttttagt tttcggagta gaacttgcat ccacaacaac tggagatgct
      841 agaattaccg atgcgcaagc aaaaatcgca gcaaaattta ttaagctacc actccgatgt
      901 gtatttgatg gtactatatc aagcatcc
//
LOCUS       DAFENC010000156          862 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.173, whole genome shotgun sequence.
ACCESSION   DAFENC010000156
VERSION     DAFENC010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..862
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.173"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..>862
                     /locus_tag="LP493_002966"
     CDS             <1..>862
                     /locus_tag="LP493_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HBL2135034.1"
                     /translation="RNLDSRTRFEQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYY
                     WVKKLDKPDKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMG
                     LTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPIL
                     DLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLK
                     ENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKR
                     IKLKLNGLSPV"
BASE COUNT          374 a          112 c          140 g          236 t
ORIGIN      
        1 agaaaccttg attcaagaac aagatttgag caagaagaaa tcaaggttaa aacaatcctt
       61 cagctcaaaa aagaatttaa attgaatcta ttactttcaa ttgcacaatt agcgaagtca
      121 acttattatt actgggtaaa aaaattagat aagccagata aatatagcaa gataaagcaa
      181 gaaattacag cgattgtaaa agaatcaaga aactcttatg gttatcgtag agtcacttta
      241 gcgttaaaga tgaaaggata tacaatcaat cataaaacag ttagaaaatt aatgtcccaa
      301 atgggactta cctgtcaaat ccgaataaag cgatataaat cttataaagg aacagtagga
      361 aaaattgcca agaatgtgtt aaaacgaaat ttttcagtag atacacccaa taaaaaatgg
      421 gtgacagacg tcactgaatt caagataaaa ggaagaaaaa tctatctatc tcctatactt
      481 gatttattta acggagaaat aattagttat agtatatcaa ctagtccaac atataaactg
      541 attgaagaaa tgcttcaaca agcaattaaa aaaaagggaa ctgagggttc actgattcta
      601 cattcagatc aaggatggca gtatcagatg ccacaatatc aaaaaaaatt aaaagagaat
      661 aacattattc aaagcatgtc tagaaaagga aattgcttag ataattctgt aatagaaaat
      721 ttttttggtg tgcttaaatc agagtttttt tatcgagaaa aattccgatc aattgagata
      781 tttcaaagta aattaaatga gtatattagg tggtataata acaaaaggat aaaactaaag
      841 ttaaatggac tatctccagt ag
//
LOCUS       DAFENC010000157          858 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.174, whole genome shotgun sequence.
ACCESSION   DAFENC010000157
VERSION     DAFENC010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..858
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.174"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(<1..434)
                     /locus_tag="LP493_002967"
     CDS             complement(<1..434)
                     /locus_tag="LP493_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2135035.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHR"
     gene            complement(451..855)
                     /gene="tnpA"
                     /locus_tag="LP493_002968"
     CDS             complement(451..855)
                     /gene="tnpA"
                     /locus_tag="LP493_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HBL2135036.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKE
                     MFWSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
BASE COUNT          258 a          139 c          136 g          325 t
ORIGIN      
        1 tgtctatgaa gcttaattct tactaatgac ttcaatttag gaactttgat gaatttacta
       61 tcaatcaaag caactgtacc attttgatta ttcgttgtat aactctgaac aggatttttc
      121 ttacttttga aacgtggaaa tccaacggat ttatcccgaa aaaaattctt gtatgcttta
      181 tctaaattaa gttgggcatt ggctaaagca aggctatcaa tttctttcaa aaacggaaat
      241 tctttcttgt atttagctgg tgtcggaaaa gtcatttttt tagaagaatc atttttaact
      301 tcttcatacg ccttttttcg gtcatcaagc attagattgt agaccttacg gacacaacca
      361 aaagatttgg caaagaagat ttcttgttcc tctgttggat agattctgaa tttgtatgct
      421 tttagttgtt ccataaagtt cacctacttt ctatttatga ttgtttcctt gattttggat
      481 atacttctta atcacatcaa ttggtgcgcc accagttgtc agaagacaaa aacttttaga
      541 ccagaacatt tctttccaaa gaaattgttt gactcttgga aagtcacgtt ttatcaatct
      601 tgagctggca cttttatagg cattgatgaa ttttgtcaat tctgttttag gttgagcttt
      661 gaacataata tgaacgtggt ctttatcatg attccactcc actaaagtaa tgtgatacga
      721 ttctgaaatt ctttcaaaag tagttttggc ataatcagat atttcatcat caatcacttg
      781 tctacgatat ttcgttacta aaacaaggtg gtaataaaga agaaatactg aatgattatt
      841 tgtatctaat tccatgtt
//
LOCUS       DAFENC010000158          849 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.175, whole genome shotgun sequence.
ACCESSION   DAFENC010000158
VERSION     DAFENC010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..849
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.175"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..720
                     /locus_tag="LP493_002969"
     CDS             <1..720
                     /locus_tag="LP493_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBL2135037.1"
                     /translation="GKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFT
                     NRLGTNKRGRLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVY
                     LANCYTLEGRKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITL
                     EEFQQANEIHCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNK
                     VQLIRLNKYRVLAGNQELNLI"
BASE COUNT          326 a          133 c          167 g          223 t
ORIGIN      
        1 gggaaaacgg aattagaaga aacaagactt tataattcaa tggtattagg tatgcaaaat
       61 tattatcaga ttgcaacgaa tgtaaatctg gattgtatga aactgaatag agctgtaatg
      121 gctatcttca ctaacagatt aggtacaaac aaaaggggca gattgagaaa aacaggcaga
      181 caacttacga caaaggaggc aacaagatat ggtaaatcta aaatgcttcg gtatgttgct
      241 ggcgagggcg aacctatttt ccctgttgga tatatccaac acagaaaacc aatggcaaag
      301 gtgtatttag cgaattgcta cactctagag ggaagaaaat ttatccacac caatctaagt
      361 gttgataaat tactgatgta ccagttaatg aaattatctt tggaaaatcg cacaatagaa
      421 tacgcagaca atcgaatttc gctattttct gctcaacatg gaaaatgtgc tataactctg
      481 gaagaatttc aacaagctaa tgaaatacat tgtcatcata ttgtaccaac tggagctggt
      541 ggaaatgacg attataaaaa tcttattttg gtaaaagagg cggtacaccg tctaatacac
      601 gctaaaacag aagaaacaat acaaaaatat atagctctat tgaagctaaa taaagtccag
      661 ctcataagac taaataaata tagagtatta gctggcaatc aagaattaaa cttgatatag
      721 gtctactaca taaatacttt tcaatataaa cacgatggaa cgcggagtgc ggtgaaagtc
      781 gcacgctccg tgtgaatggg gggaaaagtt tgagatattt ataatatcag gaacttacct
      841 atccatata
//
LOCUS       DAFENC010000159          807 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.176, whole genome shotgun sequence.
ACCESSION   DAFENC010000159
VERSION     DAFENC010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..807
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.176"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
BASE COUNT          308 a           95 c          104 g          300 t
ORIGIN      
        1 caatatataa aagaaggtat caagagtcac agtgaattta ttccgaaaag tgaaaagagc
       61 aaatataaaa tttaataaaa ataagaacta aataggaaaa cgtagacgta attttctacg
      121 ttttcctttt catatatatt aaatattacg gaaaattata taaactaatt tagtgttttg
      181 tttgtaattc ctaattttgc tccactttta gataattttt aggtctattt aactcattag
      241 acattctatg ctcatttttc tccaaatttg tttcaactct ttcgtactta attttgcgta
      301 tttgaaaatt cttcttttag agtactttta ttacgatact agtatgatat atatctacag
      361 caaacagtta aaatcttcct aaaataagcg aatagcattc ctaaaaccta taaaattttt
      421 agatgaagcg acaagtggac aattaataaa ctacttgaac atgaaattat ggatcacctt
      481 tcaaatttag aaaatggaat tcttatactt attgcgcaac atttattgat tgcaaaatta
      541 tgtgacaaaa agaactagta gaagaaggaa taatggcttg ataataaagt actacctatt
      601 aaaggtagta ctttatttaa tttagtataa attaacatac tactatattt taggtttcat
      661 attatataaa ttaataatat actaccattt gttggtagta taatttaaag gtaataagtt
      721 attcttttat tactatgttt gggttttata gcaaagaaag tttaataaga gtttggacct
      781 agcaaacaat attaatgagg tcattaa
//
LOCUS       DAFENC010000160          806 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.177, whole genome shotgun sequence.
ACCESSION   DAFENC010000160
VERSION     DAFENC010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..806
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.177"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(330..530)
                     /locus_tag="LP493_002970"
     CDS             complement(330..530)
                     /locus_tag="LP493_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL2135038.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
BASE COUNT          290 a          127 c          133 g          256 t
ORIGIN      
        1 ccatacttta taaaaatctt tgataaatct attcgaaggg tcaaatttaa accataattg
       61 tgtttttcct tccatcagca taaaagttca cctcaaaaag agtatacgaa cgaatgttct
      121 ttttgtgaag gcggaattta atatactgaa taatagaaaa caagtacttg tgccaaatta
      181 tgtgccaaaa aaattcgaat tcaacaaaat gtaaacaaat agaaaacctt ctatattaag
      241 atttcctgca ataacaaaca caacagaaga cgtgtaatag ttagtcagga acgtacaaat
      301 aacccctgta tcctttgcgg tacagggggt tattttgtat aagtagacat tgtagtttct
      361 aaactgctat gtcctaaacg tttcgatacg ctaagtatat ttactccttg ataaagtaaa
      421 atagatgcat gcgtatgtct tagtccatca ataaacagtc gaagagaaaa tagggaaaaa
      481 ttgattacta aagaaaaact tactaggtcg acggtgtagt tgattttcat acttcaatag
      541 attcgaatta aacgatttcg attggcttat accagtccta tccaacgaaa gatatatcgt
      601 tcttaactct agcggtataa cttgaagctt tacgtaaagc caatgggaat gaactggaga
      661 tgacttttta ttatttttag taatagctga tgggttaata cttacaactt tccttttcaa
      721 agtaccatat aaaaaaacgg tggggttgtt tagcgaaata aaggatctaa gccaatagct
      781 tagatccttt attctatgct ttatat
//
LOCUS       DAFENC010000161          791 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.178, whole genome shotgun sequence.
ACCESSION   DAFENC010000161
VERSION     DAFENC010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.178"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            24..716
                     /locus_tag="LP493_002971"
     CDS             24..716
                     /locus_tag="LP493_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HBL2135039.1"
                     /translation="MGLAFLLAGCTNGNESKKESTKETAKATVATTTTTSTESKSTAA
                     STETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNADKSAQLEAF
                     MTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEWSESGTGQA
                     DYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNETANNELK
                     NGFNQIVYGQAN"
BASE COUNT          282 a          151 c          159 g          199 t
ORIGIN      
        1 tgaaaaaaag gattttagta acaattggtc tagctttttt gttagctggt tgtaccaacg
       61 ggaatgaatc gaaaaaagaa tcaacaaaag aaacagcgaa agcaacagtt gcaactacta
      121 caacaactag cacagagagc aagtcaactg cagcaagtac agaaacagca gatacctcta
      181 cttcgtcaga gtcttccaaa acgactgaaa caactcaaac atctacttca agttcttctg
      241 tagaggcttc atcttcctct tcagaaagca gcgaacaagt tgaacaaaca ctgtggaatg
      301 cagacaaatc cgcacaatta gaggcattta tgaccaaatg gggccaaaca atgggacaac
      361 aatacaaaag ttatacgaat caaatgagtg tggacttata tggtcttaaa gtccctcaag
      421 ctattttgaa cggggagtgg aagatggcta ttggtggagt gcctgtttct gcagaatggt
      481 cagaaagtgg gacaggtcaa gcagactatc aaatcacagc cgtctattcc gatgcagaga
      541 cagaaccata tctgaaaaag cacgtctatc tattcgggtt tcagcaaaat cagccaaaag
      601 tattggtgac acaacaaaat caggggaatc ccgataatta tctttacttc aacgagacag
      661 cgaataatga attgaaaaat ggctttaatc aaatcgttta tggacaagca aattaatgag
      721 ataaacaagg ggttgtgaca tgtcttttat cacaacccct tgctcagttt atttgttagt
      781 cttttatttt t
//
LOCUS       DAFENC010000162          779 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.179, whole genome shotgun sequence.
ACCESSION   DAFENC010000162
VERSION     DAFENC010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..779
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.179"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..263
                     /locus_tag="LP493_002972"
     CDS             <1..263
                     /locus_tag="LP493_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HBL2135040.1"
                     /translation="KLEMAETGAGVRSSRHWKAAANIEFYYNEIQKGFDQMRELDRQT
                     NWSKKLHQDRFKFVEKYKEILEEYLRRTANDKKTRSIQHGFI"
     gene            250..468
                     /locus_tag="LP493_002973"
     CDS             250..468
                     /locus_tag="LP493_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2135041.1"
                     /translation="MDLYDIESGATLSVESDHLIINFGGKRQIILWVVDDVLFPEIVH
                     DFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            489..578
                     /locus_tag="LP493_002974"
                     /pseudo
     CDS             489..578
                     /locus_tag="LP493_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293000.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            653..>779
                     /locus_tag="LP493_002975"
     CDS             653..>779
                     /locus_tag="LP493_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HBL2135042.1"
                     /translation="MVLFDVKKYETPSAKDVDMERTKHNVAVFLSAYLSARCRVGQ"
BASE COUNT          288 a          103 c          187 g          201 t
ORIGIN      
        1 ttaagttaga aatggctgaa acaggagcag gagtgcgaag tagcaggcat tggaaagcag
       61 cagcaaacat tgaattttat tacaacgaaa ttcaaaaagg gttcgatcag atgcgtgagc
      121 tggatcggca aacaaattgg agcaagaaac ttcatcaaga tcgtttcaaa tttgtagaga
      181 agtataaaga aatattagaa gagtatttga ggaggacagc aaatgataaa aaaactcgtt
      241 caattcagca tggatttata tgatatcgaa tcaggagcaa cactatctgt ggaatcggac
      301 catctaatca taaattttgg tggaaagcgc cagattattt tgtgggtagt tgatgatgta
      361 ctgtttccag aaattgttca tgatttcgaa gaatcaaaag cggttgagtt tgaaatagtg
      421 aaaaaagtaa tggaattgat tgaaaaatac gaggaggaca gcgaatgata ccgaagttta
      481 gagcgtggga tagagaaaaa gacagaatga aggcagtagc tttggttgaa tttgctgagg
      541 cgtataaatc aggagaactc atttcacgta caaaataaaa aaagtcggat tcctccgact
      601 atgaataata tttccgacat aagtattata tcataattgg gggaatcaga ggatggtact
      661 tttcgatgta aagaaatatg agacaccaag cgcgaaagat gttgatatgg aacgcacaaa
      721 acataatgtc gctgtgtttc tttcagcata tctatcagct agatgtagag tagggcaac
//
LOCUS       DAFENC010000163          771 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.182, whole genome shotgun sequence.
ACCESSION   DAFENC010000163
VERSION     DAFENC010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..771
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.182"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..660
                     /locus_tag="LP493_002976"
     CDS             <1..660
                     /locus_tag="LP493_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL2135043.1"
                     /translation="YISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFT
                     SKMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNK
                     LSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKV
                     DKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGL
                     A"
BASE COUNT          285 a          118 c          143 g          225 t
ORIGIN      
        1 tatatttctt tgttgtgtaa agaagaaatt atcgaattac ctaaaactaa ttccacaatt
       61 ggtattgact taggtattat ggactttgcg attctttctg atggacaaaa aattgataat
      121 aataaattca cgtccaaaat ggaaaagaaa ctaaagcgtg aacaacgcaa attgtctagg
      181 cgtgctttat tggctaaaaa taaaggtacc aatctatttg aagctaaaaa ttatcaaaaa
      241 caaaaacgca aagtagctag attgcatgaa aaagtaatga atcaacgtac tgattttctg
      301 aataagttga gtacagaaat gatcaaaaat cacgatatta tctgtattga agacttaaac
      361 acaaaaggta tgttgcgaaa tcataaatta gctaaaagta tttctgatgt ttcttggtca
      421 aagtttgtga ctaaattaca atacaaggct gactggtatg gacgaaaaat catcaaagta
      481 gataaatggt ttccgtctag tcagatttgt tcagagtgcg gacataaaga tggcaagaaa
      541 tctcttgaaa ttcgagaatg gacttgtcct gtttgtcata ctcatcatga tcgtgatatc
      601 aatgctagta tcaatattct gaccgaaggt ctaagactac attctatggg attggcttag
      661 atccaatcat caagaaccgt aggaactacg gggatagctt ggtaaataag agacaccgct
      721 gttagtaaag aaatacgcta tcaagtatgc tctattccca agaagctccc a
//
LOCUS       DAFENC010000164          742 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.183, whole genome shotgun sequence.
ACCESSION   DAFENC010000164
VERSION     DAFENC010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..742
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.183"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            178..381
                     /locus_tag="LP493_002977"
     CDS             178..381
                     /locus_tag="LP493_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucocin A/sakacin P family class II
                     bacteriocin"
                     /protein_id="HBL2135044.1"
                     /translation="MKHCVILGILGTCLAGIGTGIDVDAATYYGNGLYCNKEKCWVNW
                     GQSWSEGLKRWGDNLFGSFSGGR"
     gene            381..731
                     /locus_tag="LP493_002978"
     CDS             381..731
                     /locus_tag="LP493_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBL2135045.1"
                     /translation="MTSINIDHTKKVIHELYNSLMTRPNQTKALLDITDVLFQVYKKI
                     DTAKYPEILVNKLVNYIYIVGFDNKIRFIDNDEKLLIELGDISKKAGINSKYKANFTD
                     KSQFYSYSETMPQR"
BASE COUNT          300 a           79 c          120 g          243 t
ORIGIN      
        1 gacttccttt tttgtatgga ttttttcatt tacacaaaat attttacact ctcgtcaatc
       61 attgttatat aataaaatgt tatataataa aattactaat gatatttaat attacaagca
      121 atcttaagaa attcgaaaag gaaaaaatga ttatgaaaaa gaaagaaaaa gaaagtattg
      181 aaacattgtg ttattctagg aatattagga acttgtctag ctggcattgg tacaggaata
      241 gacgttgacg cagctactta ctatggaaat ggtctttatt gtaacaaaga aaaatgttgg
      301 gtaaattggg gacaatcatg gtcagaaggg ttaaaacgtt ggggagataa tctttttggt
      361 agttttagtg gaggacgata atgacttcaa taaacattga tcacacaaaa aaagtcatac
      421 atgaattata caatagttta atgacacgac ctaatcagac gaaagcatta ttagatatta
      481 ctgatgtttt atttcaggta tataaaaaaa ttgatacagc aaaatatcct gaaattcttg
      541 taaataaatt agttaattat atttacatcg tgggttttga taataaaata cgctttattg
      601 ataatgatga aaaattatta atagaattag gggatatttc taaaaaagct ggaattaata
      661 gtaaatacaa agcaaacttt acagataaat cgcaatttta tagttattca gaaacaatgc
      721 ctcaacgata aaatatagta ta
//
LOCUS       DAFENC010000165          700 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.184, whole genome shotgun sequence.
ACCESSION   DAFENC010000165
VERSION     DAFENC010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..700
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.184"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..>700
                     /locus_tag="LP493_002979"
     CDS             <1..>700
                     /locus_tag="LP493_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HBL2135046.1"
                     /translation="DWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLTL
                     LPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNVT
                     PYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYISE
                     DLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRDM
                     YKKYTGKTGCLDST"
BASE COUNT          237 a           99 c          156 g          208 t
ORIGIN      
        1 atgactggct taatcaattt gggaatataa taatgatgca aaagccggag gatatggaat
       61 tattcccacc tgaagaaaag ggattttcct atcttatgct atttgatgat tacaataaaa
      121 ttgatcttac cttattgccc ttggaagagt tagataatta cctaaagggc gataaattaa
      181 taaaggttct aattgataaa gattgtagaa ttaaaaggga catagttccg actgatatag
      241 attatcatgt aagaaagcca agcgcaaggg agtatgatga ttgctgcaat gaattttgga
      301 atgtaacacc ttatgttatt aaaggattgt gccgtaagga aattttattt gctattgatc
      361 attttaatca gattgttcgc catgagctgc tgagaatgat atcatggaag gtcggcatcg
      421 aaacaggctt taaattaagt gtaggcaaga actataagtt tattgaaagg tatatatccg
      481 aggatttgtg ggagaaactt ttgtccacct accggatgga ttcctatgaa aacatatggg
      541 aagcattatt tctatgccat caattgttca gggcggtatc cggtgaggtg gcggaaaggc
      601 ttcattatgc ctatccggag tatgatagga atataacaaa atataccagg gacatgtata
      661 aaaaatacac tggtaaaacc ggctgcctgg atagcacata
//
LOCUS       DAFENC010000166          659 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.185, whole genome shotgun sequence.
ACCESSION   DAFENC010000166
VERSION     DAFENC010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..659
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.185"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..>659
                     /locus_tag="LP493_002980"
     CDS             <1..>659
                     /locus_tag="LP493_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBL2135047.1"
                     /translation="YISLLCKEEVRELPKSNSAVGIDLGIIDFAILSTGQKFDNNKFT
                     SKMEKKLKREQRKLSRRALLAKQKGINLFEARNYQTQKRKVARLHEKVMNQRTDFLNK
                     LSTEIIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSSFVSKLQYKADWYGRKIIKV
                     DKWFPSSQICSNCGHKDGKKSLEIREWTCPICHTHHDRDINASINILTEGLRLHSMGL
                     A"
BASE COUNT          236 a          111 c          119 g          193 t
ORIGIN      
        1 tatatttctt tgttatgcaa agaagaagtt cgcgaactac ctaaatctaa ttctgctgtt
       61 ggtattgacc taggtattat agactttgca attctttcta ccggtcaaaa atttgataat
      121 aataaattta cgtccaaaat ggaaaagaaa ctcaaacgtg aacaacgtaa gttgtcaaga
      181 cgtgccttat tagctaaaca aaaaggtatc aatctgtttg aagctagaaa ttatcaaaca
      241 caaaaacgta aagtagcacg attgcatgaa aaagtaatga atcaacgtac tgattttctg
      301 aataagttga gtacagaaat tatcaaaaat cacgatatca tctgtattga agacttaaac
      361 acaaaaggca tgttgcgtaa tcataaacta gcaaaaagta tttcggatgt ttcttggtct
      421 agttttgtgt ctaaattaca atacaaggct gactggtacg gtcggaaaat catcaaagta
      481 gataagtggt ttccatctag ccaaatctgt tcgaattgtg gacataaaga cggcaagaaa
      541 tctctcgaaa ttcgagaatg gacttgccct atttgtcata ctcatcatga ccgagatatc
      601 aacgctagta tcaatatcct gaccgaaggt ctaaggctac actctatggg attggctta
//
LOCUS       DAFENC010000167          630 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.186, whole genome shotgun sequence.
ACCESSION   DAFENC010000167
VERSION     DAFENC010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..630
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.186"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..>630
                     /locus_tag="LP493_002981"
     rRNA            <1..>630
                     /locus_tag="LP493_002981"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          156 a          144 c          196 g          134 t
ORIGIN      
        1 gaaagccccc ggctcaaccg gggagggtca ttggaaactg ggagacttga gtgcagaaga
       61 ggagagtgga attccatgtg tagcggtgaa atgcgtagat atatggagga acaccagtgg
      121 cgaaggcggc tctctggtct gtaactgacg ctgaggctcg aaagcgtggg gagcaaacag
      181 gattagatac cctggtagtc cacgccgtaa acgatgagtg ctaagtgttg gagggtttcc
      241 gcccttcagt gctgcagcta acgcattaag cactccgcct ggggagtacg accgcaaggt
      301 tgaaactcaa aggaattgac gggggcccgc acaagcggtg gagcatgtgg tttaattcga
      361 agcaacgcga agaaccttac caggtcttga catcctttga ccactctaga gatagagctt
      421 ccccttcggg ggcaaagtga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg
      481 ttgggttaag tcccgcaacg agcgcaaccc ttattgttag ttgccatcat tcagttgggc
      541 actctagcaa gactgccggt gacaaaccgg aggaaggtgg ggatgacgtc aaatcatcat
      601 gccccttatg acctgggcta cacacgtgct
//
LOCUS       DAFENC010000168          615 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.187, whole genome shotgun sequence.
ACCESSION   DAFENC010000168
VERSION     DAFENC010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..615
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.187"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..>615
                     /locus_tag="LP493_002982"
     CDS             <1..>615
                     /locus_tag="LP493_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
                     /protein_id="HBL2135048.1"
                     /translation="ALSKRGIQISRRKISRIMKNRGLKSSYTVAYFKVHHSTCNEAKT
                     TNVLNRKFLRDNPLEAIVTDLTYVRVGKKWNYVCFILDLFNREILGYSCGEHKDAVLV
                     KKAFSRIKQPLTEVEIFHTDRGKEFDNQAIDELLTTFDINRSLSHKGCPFDNAVAEST
                     YKSLKVEFVYQYTFETLQQLDLELFDYVNWWNHLRLHGTLGYET"
BASE COUNT          211 a          105 c          117 g          182 t
ORIGIN      
        1 aagccttatc aaaacgaggc attcagatca gccgacgaaa aattagtaga atcatgaaaa
       61 atagaggatt aaaatcgagc tatactgttg cttattttaa agtacatcat tctacttgca
      121 atgaagccaa aacgacaaac gtattgaatc gtaaattctt aagagacaac ccattagaag
      181 cgatcgtaac agacttgact tatgtacgag tcgggaaaaa atggaattat gtctgtttca
      241 ttttggatct gttcaatcga gaaattctcg gctattcttg tggagaacat aaagatgccg
      301 ttctagtaaa aaaagcattt agccgtatca aacaacctct gacagaggtt gagatttttc
      361 atactgatcg tggaaaagag tttgataacc aagctattga tgaattatta acaacttttg
      421 acatcaatcg atcattgagt cataaaggct gtccttttga taatgccgta gctgaatcaa
      481 cttataagtc gttgaaagta gaatttgtct atcaatacac atttgaaacc ttacaacaat
      541 tggatttgga gttatttgac tatgtcaatt ggtggaacca ccttcggttg cacggtacac
      601 ttggctacga gacac
//
LOCUS       DAFENC010000169          569 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.188, whole genome shotgun sequence.
ACCESSION   DAFENC010000169
VERSION     DAFENC010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..569
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.188"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
BASE COUNT          185 a           81 c           81 g          222 t
ORIGIN      
        1 tcttgatgtg atatccttgt cttttttgta atgtttttaa cttattgctt ttgcaaaatt
       61 tatttacctg ttttctggat caacgatagt gtacattatg ctatccttgt ttggatttta
      121 ggacgtttaa agaggcactt ttttacataa cttaatccat agacctttta agcatgctgt
      181 gagataataa taaagaagag tttaaagcgc accccaaacc acttccccat aagtgtatta
      241 cgctttaaac tcttttatat ttgaattcac taagaagcat accatatttt tgaaaaaaag
      301 tgagaaaaaa ggcttataat taggatttag agtaattaat tagatgttta ttttatagga
      361 ctgatactat agattacaaa tagtatcgta tttcgcaatc ttaaaattat cttcttactg
      421 tgaataagat aataaaattt gtatttgtcc tttttaggta acttatttta atctatatac
      481 ctttctggat caacgaaagt atactttata tagtcataac gccgatggta actatgcact
      541 gtaacgataa tgctgctaaa atatctttt
//
LOCUS       DAFENC010000170          548 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.189, whole genome shotgun sequence.
ACCESSION   DAFENC010000170
VERSION     DAFENC010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..548
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.189"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..>548
                     /locus_tag="LP493_002983"
     CDS             <1..>548
                     /locus_tag="LP493_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HBL2135049.1"
                     /translation="DRFHIIKHMNQAFNELRIREMNELRKVGQKSQAEKLKKNWRFLL
                     KNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLGFSTSLKEAYPYFHELVEAFRDK
                     DPDLFFSLLAELPETLDDGFREKLQNLLTYEEGITNAMIYPYTNGKIEAKNTHIKTMK
                     RVSYGFKSFENMRIRIFLINQL"
BASE COUNT          194 a          106 c          101 g          147 t
ORIGIN      
        1 gatcggtttc atattatcaa acacatgaat caagccttta atgagttgcg tatccgtgaa
       61 atgaatgaac ttcgtaaagt aggacagaaa agtcaggcag aaaaactgaa aaagaactgg
      121 cgctttttgc taaaaaatcg tgcaaacatc aaccattatg aatacaaaac atggaaaagt
      181 tttcgagcac caaaataccc atttcttacg gaagcgatga tgattgatcg attgcttggc
      241 ttttctacgt ccctgaagga ggcgtatccc tattttcatg aattagttga agcctttcga
      301 gacaaagacc ctgacttatt tttctcctta ttggcagaac ttcccgaaac gttagatgac
      361 ggctttcggg aaaagctcca aaaccttctg acctatgaag aaggcatcac caacgcgatg
      421 atctatcctt acaccaatgg aaaaatagaa gcgaagaata cccatataaa gacaatgaaa
      481 cgagtatcct acggatttaa atcatttgag aacatgagaa ttagaatctt tttgatcaat
      541 caattaat
//
LOCUS       DAFENC010000171          513 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.denovo.191, whole genome shotgun sequence.
ACCESSION   DAFENC010000171
VERSION     DAFENC010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..513
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.denovo.191"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..>513
                     /locus_tag="LP493_002984"
     CDS             <1..>513
                     /locus_tag="LP493_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2135050.1"
                     /translation="GENIPAGYHKVTFTAGEGTSIESGTTVFAVKDGVSLPEDKLPVL
                     KAKDGYTDAKWPEEATQPITADDTEFVSSATKLDDKSDADKYNPEGQKVTTELNKEPD
                     AFEGIKNKEDLPKDTKYTWKEKVDVSAAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRS
                     DADKYEPTVEG"
BASE COUNT          207 a           82 c          119 g          105 t
ORIGIN      
        1 aggagaaaac attcctgcag gctaccacaa agtaaccttc accgcaggag aaggaacaag
       61 tattgaaagt ggaacaacag tctttgcagt gaaagacggc gtaagcttac cagaagataa
      121 acttccagtg ttgaaagcaa aagatggtta tacagatgcg aaatggccag aggaagcaac
      181 tcaaccaatt acagcagatg atacagaatt tgtatcaagt gcaacaaaac tggatgataa
      241 atctgacgct gacaaatata atcctgaagg tcaaaaagtg actacagaat tgaataagga
      301 accagacgca tttgagggaa ttaagaacaa agaagattta ccaaaagata ctaagtatac
      361 ttggaaagaa aaagtagatg ttagcgcagc tggaaataaa aaagggactg ttgtagtgac
      421 atatccagat ggatcatctg atgaagttga agtagatgtt acagtgacag acaatcgttc
      481 tgacgccgat aaatatgagc caacagtaga agg
//
LOCUS       DAFENC010000172        24403 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.guided.038, whole genome shotgun sequence.
ACCESSION   DAFENC010000172
VERSION     DAFENC010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24403
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.guided.038"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(621..812)
                     /locus_tag="LP493_002985"
                     /pseudo
     CDS             complement(621..812)
                     /locus_tag="LP493_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008791949.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein Fic"
     gene            complement(974..2365)
                     /locus_tag="LP493_002986"
     CDS             complement(974..2365)
                     /locus_tag="LP493_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008816766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL2135051.1"
                     /translation="MASIRERNGKFNVIYSYTNEKGERKQKWETYETKAEAKRRKKEI
                     EYKKEMGSFVVRKCKTLDELITEYVALYGKENWALSTYEGNVSLINNYILPIIGDTKL
                     SEINTRFIERYYQSLLKRRAVINPLNKTSRNEFVSSSTVRDINKLLRNCFEQAVKWEL
                     MEKNPCTHATVPKHKSQKRDIWTADTLMYALSVCEDERLKLAINLSFSCSLRLGELLG
                     LTWDCVDISHEAIEENRAYVFINKESQRIRKESLNALDGKDVLLVFPTNHKKNSTVRI
                     LKTPKTESSVRKIFLPKSVANMLVDWKAEQDEMKEILGDEYMDYNLVMASTFGLPLGD
                     GAIRGPLKKLIEDYNLPPVVFHSFRHSSVTYKLKLNGGDIKAVQGDSGHAQVNMVTDV
                     YSHILDDDRRKNAELFEEAFYEKKNLDPQMHVQQENNNTTVADEVDPELLAKVLANPE
                     MRALLNSLAKTMK"
     gene            complement(2367..3356)
                     /locus_tag="LP493_002987"
     CDS             complement(2367..3356)
                     /locus_tag="LP493_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005423640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2135052.1"
                     /translation="MATAIMKQKEVPEMDDVEEIISKISEDSPYKRRPTQKRTWMTVP
                     EMGKLLGLKKTDRYWLVHKNVFESKEIAGKIRINIASFEKWYANQIKYHKVTGEEPGK
                     ELKSWSYSVKEVADLLGVDEYLVYDLLKKNQMEAVIVDYWKRIPKESFQNWYKSQSRY
                     RTKEDRKKDALLEDATITMPEMAQLLGTTRSAVYTILDNPKYSHFFEFIVIAEKKRIT
                     KESFRKFLEGQDRYKLDPSNDYEELAQEQNIALANFRRKKLSQTGIRGSNGNIKYLTF
                     DEASYLAKVSRSMINKWADKGKFTVIKVGSRVRIRRDEFEDWMEQRDLERSMQ"
     gene            complement(3477..3653)
                     /locus_tag="LP493_002988"
     CDS             complement(3477..3653)
                     /locus_tag="LP493_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005426062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2135053.1"
                     /translation="MSEKRCYTVQELQEILGVSRPTIYNLLKKKEFRWIQLDGGKYRI
                     SKKSFDDWLDNLEQ"
     gene            complement(3920..4363)
                     /locus_tag="LP493_002989"
     CDS             complement(3920..4363)
                     /locus_tag="LP493_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005719578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2135054.1"
                     /translation="MKIREVNKNKKQFISLLLLADEQESMVDRYLEKGTMYVLEDNDV
                     KAECVVTDEGNGILEIKNIAVDPENQGKGYGKALIDFLASKYADEYSVLQVGTGDSPL
                     TIPFYEKCGFVRSHKIPNFFTDNYDHTIYEGGVQLIDMVYLQRHI"
     gene            complement(4434..5060)
                     /locus_tag="LP493_002990"
     CDS             complement(4434..5060)
                     /locus_tag="LP493_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008789344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL2135055.1"
                     /translation="MFDKHKRESLLLRDLLKKLIIIVIGSIVAAYGITLALYAGFGGA
                     TLAVLWQGIAETFHLSIGMASFVVAVGMILFALIYDKSQIHIGTVLYQIVYSTCVDVF
                     ATCHVYSTYRWFNFFIMLLGVILFAVGTGLYASASLGRGSYEAVTFALAEKNNWQVKI
                     VRIALDILVVIIGVLLGGKFGICTIITVIISGPIIQFVNAKAKRILKI"
     gene            complement(5191..5514)
                     /locus_tag="LP493_002991"
     CDS             complement(5191..5514)
                     /locus_tag="LP493_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004613237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS biosynthesis protein"
                     /protein_id="HBL2135056.1"
                     /translation="MKIEGNQKELDAMVEFHKGNRVEGLRLQEEFAAEFRKEYKDKDH
                     CPCLKACRYHGNCKECVAIHRAHQEHVPNCMRPLINKKLKLMSELTEHTLANEIEAPH
                     EILRK"
     gene            complement(5570..5995)
                     /locus_tag="LP493_002992"
     CDS             complement(5570..5995)
                     /locus_tag="LP493_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003864588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2135057.1"
                     /translation="MIRKLLNGDIDRIADIWLKTNLKAHYFISNQYWKSNYELVKEMM
                     SQYEVYVFEADKMIQGFVGLNDKYIEGIFVSDEMQSCGIGKLLLDYVKDKKVSLRLNV
                     YQKNARAISFYQREGFIIQYEGLDETTGEKEYTMLWKRK"
     gene            6379..6765
                     /gene="mobC"
                     /locus_tag="LP493_002993"
     CDS             6379..6765
                     /gene="mobC"
                     /locus_tag="LP493_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009263517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBL2135058.1"
                     /translation="MAPKKKEKNLKRSNIITLKLTDIELAVLNEAADVTGLSRSEYVR
                     KLLLEKQINHQIEVVADMNDLRKLVSEYGKIGSNLNQIAKHFNSGGSQSRAIENEIHQ
                     CITDLFLLRKEVLKLAGGMNGNRKTH"
     gene            6743..8296
                     /locus_tag="LP493_002994"
     CDS             6743..8296
                     /locus_tag="LP493_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004606465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBL2135059.1"
                     /translation="MAIVKHIKSRNANYSAAINYLLFEHDEKTGKKIVDESGRSIMRK
                     EFYMDGLNCDPMSFDKECELTNAHFHKNKKRADIKSHHYIISYDPADVTENGLTGPIA
                     QAISLELAKQMFPGYQALVVTHTDGHNESGNIHTHIVINSVRKTAVERQPYMDKPHEE
                     AAGYKHRSTDKFMNAFKKTVMERCQQEGFHQIDLLVPAERKTTQKEYIAQKHGQQKLD
                     EINQKIIEDGLKPTSTVFLTQKEYLRNAIDECASTSNSFDEFQSKLLEQFQISVIEHR
                     GRYSYLHPDRQKRITERSLGTRYGKEHLKQTFLRKDPLAILYVRSHLRLVVNLQTNVK
                     AMQSPAYAHRVKLSNLQQMANTIIYVQEHGFDTQSDLKNTLVASKQELKEMQTQFAQH
                     RSDLRILNDQIRYTGQYYANKEVYSQFSKAKYKGKYRKEHAKEIQKYEEARNWLKSFY
                     QDGNMTSLKTLTLQKEKLQQQIASEEEAISSLKEKLKDLDTADQNVDAILQMQIPEPV
                     RSKNKDLER"
     gene            8326..8652
                     /locus_tag="LP493_002995"
     CDS             8326..8652
                     /locus_tag="LP493_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009263519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2135060.1"
                     /translation="MTQEEFNIVFELQMRKCADILAHKKKEYTGDNIDRLSAFKIAAA
                     LQNCDPKAALAGMMSKHVVSLYDMCYSTLLHFDMEQWDEKITDCINYLILLKALVKEE
                     QAYGSH"
     gene            8639..9418
                     /locus_tag="LP493_002996"
     CDS             8639..9418
                     /locus_tag="LP493_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009267089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent thymidylate synthase"
                     /protein_id="HBL2135061.1"
                     /translation="MDHIETAILNCYGIREAEQNMVFAARLTQHGHTIQNMADLMDLY
                     RQSYSQKTVENIAGLPHPTVQKFMVITVAVVGASRRFLAQITRHQNEVKYMSASLQYS
                     NYSGHAAFAIPYGIMKADKEIQDIYKKSCQSDLDHYAELCALGIDHDSAGYATPQGLR
                     NVLIISATPYQWKHMIGQRTCRRNTDETRIVMLYIWQRLYKLSPILFAPDLTGPFCQR
                     GSCMEKQMSCQNPISKLWMPADILKTDYPLLIRKEMSSHKD"
     gene            9408..9821
                     /locus_tag="LP493_002997"
     CDS             9408..9821
                     /locus_tag="LP493_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008976873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyuridine 5'-triphosphate
                     nucleotidohydrolase"
                     /protein_id="HBL2135062.1"
                     /translation="MKIKLIDFGLKADHHPFRPHENDAGADVFMPYDCVLKPGEVARI
                     PLGFGLIIPDGFAGYVFPRSSMAAKGLVCELPPIDSGYRGEIHAIISNVSTSSQTIHK
                     DTRVGQLVITPVVIADFVLDLGEERGTGAFGSTGE"
     gene            9826..10104
                     /locus_tag="LP493_002998"
     CDS             9826..10104
                     /locus_tag="LP493_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006426622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2135063.1"
                     /translation="MITFGRKLKHLRQKNHLTQKELGMAVGFPDSCADVRIAQYESDV
                     RTPKEDLMKLFASTLGVPVELFTVPVLSEPREYEAAEYWRYELGAELD"
     gene            complement(10234..10662)
                     /locus_tag="LP493_002999"
     CDS             complement(10234..10662)
                     /locus_tag="LP493_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003864549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2135064.1"
                     /translation="MKKNNITLVFVAIVFSIIVGMIIGKSLLKYKEGEPDVVGSFSMN
                     RDENFTVVANRKNISDKEAFARLLLKMYKENSFHSIKFSTDHGYATSLDMTVYSWKED
                     IENGESIMQIEFRPIEYGKDYDLVHNPDKYVLLIDGTEIK"
     gene            10986..11360
                     /locus_tag="LP493_003000"
     CDS             10986..11360
                     /locus_tag="LP493_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001129922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TnpV protein"
                     /protein_id="HBL2135065.1"
                     /translation="MVQSIFEEMGGRYERQGEYILPCLTIPPEKEQSIDLFGRRHLDY
                     LREYRKITYTNLLTSGRLNAYLADIDRQAQEHFERLIEGMKQAQGITECLKEENALEW
                     TGRTNNIRACAREIVEKEIIFA"
     gene            11727..13646
                     /gene="tet(O)"
                     /locus_tag="LP493_003001"
     CDS             11727..13646
                     /gene="tet(O)"
                     /locus_tag="LP493_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032490535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(O)"
                     /protein_id="HBL2135066.1"
                     /translation="MKIINLGILAHVDAGKTTLTESLLYTSGAIAEPGSVDKGTTRTD
                     TMNLERQRGITIQTAVTSFQWEDVKVNIIDTPGHMDFLAEVYRSLSVLDGAVLLVSAK
                     DGIQAQTRILFHALQTMKIPTIFFINKIDQEGIDLPMVYQEMKAKLSSEIIVKQKVGQ
                     HPHINVTDNDDMEQWDAVIMGNDELLEKYMSGKPFKMSELEQEENRRFQNGTLFPVYH
                     GSAKNNLGIRQLIEVIASKFYSSTPEGQSELCGQVFKIEYSEKRRRFVYVRIYSGTLH
                     LRDVIKISEKEKIKITEMCVPTNGELCSSDTACSGDIVILPNDVLQLNSILGNEMLLP
                     QRTFIENPLPMLQTTIAAKKSEQREILLGALTEISDGDPLLKYYVDTTTHEIILSFLG
                     KVQMEVICAILEEKYHVEAEIKEPTVIYMERPLRKAEYTIHIEVPPNPFWASVGLSIE
                     PLPIGSGVQYESRVSLGYLNQSFQNAVMEGVLYGCEQGLYGWKVTDCKICFEYGLYYS
                     PVSTPADFRLLSPIVLEQALKKAGTELLEPYLHFEIYAPQEYLSRAYHDAPRYCADIV
                     STQIKNDEVILKGEIPARCIQEYRNDLTYFTNGQGVCLTELKGYQPATGKLICQPRRP
                     NSRIDKVRHMFHKLA"
     gene            13698..13871
                     /locus_tag="LP493_003002"
     CDS             13698..13871
                     /locus_tag="LP493_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002779755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HBL2135067.1"
                     /translation="MMKCEWILCPVCGSKTRNKIRKDTVLKNYPLYCPKCRQERLIKV
                     DNLKITVIKEPDA"
     gene            complement(14516..15499)
                     /locus_tag="LP493_003003"
     CDS             complement(14516..15499)
                     /locus_tag="LP493_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004607971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBL2135068.1"
                     /translation="MKRLPKYTPAEVRNDPYGFTYKEMSEVIGENEAKALYEELYKQL
                     PRKKNLSMLVKNICKSSDTEKYVYELKDNKYIETVFIKRRDGGTVCVSTQVGCPVGCI
                     FCESGRNGFVRNLTSSEIVQQIILLRRKVNRIVFMGMGEPLFNYDNLIKAIHILRDRY
                     GLNFPTDGITISTVGPVDQLKKLREEHLKIQLTISLHAATQSARNRIIPHMRIYAIED
                     VVKQALSYSERHNRKIVFAYLLLPGINDRPSDVRQLAKWFRGKKVMINVLQYNPTSNS
                     RIKAPQKREIVAFKHQLEQAGLEVTMRVSHGREINAACGQLANTYNKFKKK"
     gene            complement(15516..15701)
                     /locus_tag="LP493_003004"
     CDS             complement(15516..15701)
                     /locus_tag="LP493_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL2135069.1"
                     /translation="MLKKYWIKCPICNGKTRVQVFHNTVLKDFPLFCPKCKLTHIIDV
                     EKLEIVIKNTEKQTFII"
     gene            16100..16456
                     /locus_tag="LP493_003005"
     CDS             16100..16456
                     /locus_tag="LP493_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2135070.1"
                     /translation="MAKRPVPLYDFKAFGAAIKAARNEYGESRKKVSDELYISPRYLA
                     NIENKGQQPSLQVFYDLVTRYHISVDQFFFPNSNAEKSTGRRQLDALLDGMSDKGIRI
                     VTATAREITEVEKAED"
     gene            complement(16459..16650)
                     /locus_tag="LP493_003006"
     CDS             complement(16459..16650)
                     /locus_tag="LP493_003006"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2135071.1"
                     /translation="MINGKDQEIITINKTGNSILNNAKYSADNTDEWYTTFVARSFDF
                     GRKKRLQPPCAAISRFLIL"
     gene            complement(16679..16876)
                     /locus_tag="LP493_003007"
     CDS             complement(16679..16876)
                     /locus_tag="LP493_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014073062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2135072.1"
                     /translation="MARPKKNGTYLNVCIETPIYERLENFCKDAGHTKTVAVERALIS
                     YFDEYEEMKKKLKELESNQDK"
     gene            complement(17136..17426)
                     /locus_tag="LP493_003008"
     CDS             complement(17136..17426)
                     /locus_tag="LP493_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015535390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HBL2135073.1"
                     /translation="MRRLKCEKETIILTNEDDGFYDVYTFNQSLQKRLRAFAEKYPDD
                     CWLKGSSEDGSETYIIKKGRLSLNLRPPYSKDRIHKATERIIEEQKEQSKDS"
     gene            complement(17430..18314)
                     /locus_tag="LP493_003009"
     CDS             complement(17430..18314)
                     /locus_tag="LP493_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4316 domain-containing protein"
                     /protein_id="HBL2135074.1"
                     /translation="MKLNQFAVYRVDQQTAGKALWHLPYQEARQQNVSITVENYRLVS
                     IHEMQENEKVADIWKRMKKQCEVSDVLVLNKNGEISCYYVDENYPQYLAGFIRINTSG
                     ALITMETENYQIDGKKGNWIATDTIIIDGKQFYLMEHQVYRDQAQGVILDAYGKMVVE
                     ECKKFDEKTKQKIHDYIQQQVPLNPVEQLKQDGKIRLEHYQKFYQNGTYERSRESGTE
                     ANYDMVDGLVNNQKKNQEKTSDASSNNQTSRNQQDGKSKKRRSVIKRLHQKQIAIARR
                     SGKPIPKYLDQEMERKRG"
     gene            complement(18304..18564)
                     /locus_tag="LP493_003010"
     CDS             complement(18304..18564)
                     /locus_tag="LP493_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005423594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HBL2135075.1"
                     /translation="MRNVNLEENELTITAIFQQHTKEETIQTLKEALEVMEQEESDPE
                     NDEMIEIINSTVGKLQQIEDKYYYSLDLNYYLNNLENDAYEA"
     gene            complement(18561..20582)
                     /locus_tag="LP493_003011"
     CDS             complement(18561..20582)
                     /locus_tag="LP493_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015535387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1738 domain-containing protein"
                     /protein_id="HBL2135076.1"
                     /translation="MTEQNKTTTIPLPVPGKDMDSIMQSLESGVEELFTSNRYQEFLK
                     TMAKFHNYSFNNTMLIAMQRPDATLVTSYKNWQSMGRQVMKGEKGITIIAPAPYKKMK
                     EKEVLDENQRPIMGSDGKPKTEQVEVTVPHFKAVTVFDIAQTSGEPIQTLAPELLTAA
                     VQDFDSFMQAIQKISPVPIRFDEIDDNANGYYHNADKEIVIKKGLSESQTLKTAIHET
                     VHAKLHDREIMESLGVEKDRLTKEVEAESVAYCVCSSFGLDTSDYSFPYIAGWSSSRE
                     MKEMKASMDVIRKTAGEMIDQLTEELEIILEEKQKTELHDKYGILVDALEAAGYRYDY
                     RESEPGHIVLAPDGTHEIAGYLQFESWGDIKDWLEDTIAEGTDISERVDRALYPFKFD
                     YTLEEEMFRGNGDRYAIYHVDEDTPGKQHLFMNMAMVKEDGITIDAANYKCVYSGRLH
                     ENEKLDDLYAVFNDNPPADYKAHSMSVSDVIITNRGGDMQAYYVDRFGFAELPDFAVQ
                     REKILDIVPEIENVDYENDLTCISFYAAECAEFPVMGEVHYDLTLPEALEAYEKIPSE
                     RMHGLKCVGFDLKDGSDYEGMQSLMIEGKIQKEFLNSIPGFRENSYVQNAISRVEKYL
                     EERHPNVENPLESNKKVDNEKNISKEKNEKELNIQMKPIPKKKRGEMSL"
     gene            complement(20665..21714)
                     /locus_tag="LP493_003012"
     CDS             complement(20665..21714)
                     /locus_tag="LP493_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005334802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2135077.1"
                     /translation="MNFNEFVSEVKDNIKLFLPEEYENVEVSTMECQQLNRAYTGLMV
                     RKEGEMLTPTINLNQLYEAYKAQPGVTMETVCRKIADIVIEAPIQVDLKAIFNYEDVK
                     DKLFIRVSSAEANKEVLENAPHQLKEDLAITYHVAVDKDENGLSSMFIKNDLLEQYGI
                     SAEQLHEDAMKSSPRVMVPEVSSIGALIDEMYQKNILMLTPDEREMLQETLQESSEMP
                     TFFVVTNTERVDGAGVIFYPEFMDNMGELLGNDFFILPSSIHEMLILPDDGQVDAEML
                     RDMVKEVNATQVAPAERLTNDVYHFDTKDHVFEKADRFTERQKEKEAQAAKTEKAGKE
                     QPDQKPKTKKHDMEL"
     gene            complement(21743..23854)
                     /locus_tag="LP493_003013"
     CDS             complement(21743..23854)
                     /locus_tag="LP493_003013"
                     /inference="COORDINATES: protein motif:HMM:TIGR01056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HBL2135078.1"
                     /translation="MYLVIAEKPSVSRAIAEVIGAQEREDGYLQGTDCMVSWCFGHLA
                     EYVSPDAYDEKFNQWRYEDLPIIPKDWKVTVSEDKKDQFYILKRLLNSPEIEYVVNAC
                     DAGREGELIFKHVYDLSGSKKPVKRLWISSLEDSAILDGMQHLRSAEEYRHLAEAAVC
                     RSQADWLVGMNATRAYTTKYFKKLTVGRVQTPTLAMLVERAGQISNFQKEKYFNVELD
                     CDGIPAVKPKIFDPDEAEQLRSRCQGSEAIVTAVKETEKKVKAPKLYDLTTLQREANR
                     IYGMTAKQTLDTAQNLYEKKLITYPRTDSQYLTEDMEQTARNVVRQIYEKYQLTGPFD
                     QPEQPDVKKVMNNSKVTDHHAIIPTMELSSCHLDELKSWEEKILFLIAVHTVMAMSKE
                     HVYQETEIEVECQGEIFKAKGKTVLQDGWKLFENCFKNKDRMAIVDPDQEMKEKIPKV
                     TQGQTFYAVAAEKTEHFTSPPKPYSEDTLLAAMETAGNKEFDEDTEKKGLGTPATRAG
                     IIEKLIYSQYATRKGKQILPTEDGKVLVEILPDFLKSASMTAEWENQLLLMEHGEIAP
                     EQFMTGIKNMLTMMLNGCDAISEEETRRFQTRESIGTCPVCGSLVYESKPNFYCSNHD
                     CHFALWKDNRYLQSMEKTMDKKMAAELLKNGSVHVKDLYSRKKNMYFEADLHMDTDET
                     GKVNFSLSFPKKKSKNKSKKK"
     gene            complement(23927..>24403)
                     /locus_tag="LP493_003014"
     CDS             complement(23927..>24403)
                     /locus_tag="LP493_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003864570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HBL2135079.1"
                     /translation="DDITDDSTKEFLTVTTKNNNTFYIVIDRSATSQNVYMLSQIDEN
                     DLSEFLDKDSTAAVVTPQPDTSKVVLDETNNEDVDKEATVDPEKTSSAKTNMGAMATI
                     LILALGGVAAYYYFKIYKPKKEEDEDDQPEGLETGGLEEVPDEEESEDEDFEENEK"
BASE COUNT         6970 a         5144 c         4384 g         7905 t
ORIGIN      
        1 tttaggacat agcagtttag aaactacaat gtctacttat cttcatattg ttcgagagct
       61 tgaagatcag gataaagaaa aaatcaatac tgtgttcgat agtttatata aaaatgataa
      121 ctagtttggc acatttttgg cacaaataca aaacaaaccc ctgtaccgca aaggatacag
      181 gggttattta tacgttcctg actggaattg aaccagcgac ctatcgctta ggagagctcc
      241 aacctattgt cactctctgt caatctgagg taaggtaaac ccatatggga cactatataa
      301 aactgtttcc gattcaattc gagttattct gaataccccc tctgtcaagc tctgtaaagc
      361 tctgaaagtt agctgattgt ttgccccagc taataatcgg ggaatgcctt gatattacca
      421 tcgacatctg ttatatgacc accatgcttc gtacgttcga tcatggtaaa cagtattcaa
      481 ttaaactttc ctatcataag tacaagatat tttcttgtct ataaataata taacgcatac
      541 gagacggttt gtccatgcgt ttttgactgg caaatttata agctgctttc atatttttaa
      601 acacggacat aaccagtaga tataccttcg attcggttgg atgctcccgt actctgaatc
      661 aatgcaactt ctaagagtgt tttcaattca tctacattgg cttcgagaaa taattcctgt
      721 ttgcctttat gttcatggat gctgctaacc atctgaacaa tttcaggtgt taacaacttc
      781 gcaggactta caataaaatc aaagtctctc ataggaatct ccttcatttc agatttatct
      841 ccgtcattct atcatcaaat gatggagata gaatatccat atacacaata aatatcctca
      901 tttcatccat atattatatc gttttatgaa tcgttttttc actaaaatta cactattttt
      961 tcactatttt tcattacttc atcgtcttcg ccagtgaatt gagcaatgcc cgcatctctg
     1021 gattcgccaa tacttttgcc agaagttccg gatcgacttc atcagcaaca gtagtattat
     1081 tattttcctg ctgtacatgc atctgtggat ccagattctt tttctcataa aatgcttctt
     1141 caaaaagctc tgcatttttc cttctgtcat catccagaat atgagagtac acatctgtaa
     1201 ccatattgac ctgagcatgg ccagaatcac cctgtaccgc cttgatgtct ccaccattca
     1261 gtttcagctt ataagtaaca ctgctatgac gaaaactgtg aaatacaacc ggtgggagat
     1321 tatagtcctc gatcaatttc tttaaagggc cacggattgc tccatcacca agaggaagac
     1381 caaaggtact tgccataacc aggttatagt ccatatattc gtcacccagg atttctttca
     1441 tttcatcctg ctcagctttc cagtctacaa gcatattagc aacgctcttc ggtaagaata
     1501 tcttacgtac actactttct gtcttcggtg ttttcagaat acggaccgta gaattcttct
     1561 tatgatttgt cggaaatacc aacaacacat cttttccatc caatgcattt aaagattctt
     1621 ttcttatacg ctgtgattct ttgttgatga agacatatgc acggttttct tcaattgcct
     1681 catgagaaat atctacacaa tcccaggtaa gaccaagcag ctcaccaagt cgcagggaac
     1741 atgagaaaga tagattaatt gcgagcttta atcgttcatc ttcacagaca ctgagcgcat
     1801 acatcaatgt atccgctgtc cagatgtctc ttttttgtga tttatgtttt ggtacagtcg
     1861 catgggtgca aggattcttc tccatcaact cccatttcac tgcctgttca aaacagtttc
     1921 taagcagctt attaatatcc ctgaccgtac tggaagatac aaattcattt cgactggttt
     1981 tattcaatgg attgataact gcacgtctct tcaaaagact ctgataatat ctttcgatga
     2041 aacgggtatt gatctctgag agtttcgtat caccaatgat cggaagaata tagttattga
     2101 taagagagac atttccttca tatgtagaaa gcgcccagtt ttctttgcca taaagtgcaa
     2161 catattctgt aataagctcg tccagtgttt tgcatttacg gacgacaaat gatcccatct
     2221 cttttttata ttcaatttct ttttttcttc tctttgcttc ggctttcgtt tcataggttt
     2281 cccacttctg tttcctctca cctttttcat tcgtataaga atagattaca ttaaattttc
     2341 cgtttcgttc tcttatagat gccatattat tgcatactcc tttccaaatc tctttgctcc
     2401 atccagtcct caaattcatc ccgacggatc ctaactcgac tgccaacttt tattactgtg
     2461 aactttcctt tatccgccca cttgttgatc atgcttctgc tgacctttgc cagataggaa
     2521 gcttcatcaa aagtaagata ctttatattt ccattgcttc ctcgtattcc ggtctgtgat
     2581 aatttcttcc gccggaaatt agccagggca atattttgtt cctgtgcaag ttcttcataa
     2641 tcattcgatg gatccagctt ataccgatcc tgaccttcca ggaattttcg aaaactctct
     2701 tttgtgatcc ttttcttttc tgcaatcaca atgaattcaa aaaaatgact atactttgga
     2761 ttatcaagaa ttgtatatac tgcgcttctg gttgttccaa gcagctgtgc catctcaggc
     2821 atcgtaattg ttgcatcttc cagaagagcg tctttttttc tgtcttcctt tgttcgatac
     2881 cgggactggc ttttatacca gttctgaaaa gattcttttg gtattcgttt ccagtaatcg
     2941 acaataacag cttccatttg atttttcttg agtaaatcat aaacaagata ctcatcaaca
     3001 cccaacagat ccgcaacttc cttaacggaa taggaccagg atttcaattc tttccctggt
     3061 tcttctccgg taactttatg gtatttaatc tgattggcgt accatttttc aaagctggca
     3121 atattgattc gtatctttcc agcaatctct ttagattcaa aaacattttt atgcaccagc
     3181 cagtatcgat ctgtcttttt taatcccagc agctttccca tttccggcac ggtcatccag
     3241 gttctctttt gtgtcggacg ccgtttgtaa ggactgtctt ctgatatctt tgaaatgatc
     3301 tcttcaacat cgtccatttc cggaacttct ttttgtttca taattgctgt tgccatttat
     3361 tcttcacttc ctgtcttttt tagtgttagt tttttttctt atatcatatc tcaaatccag
     3421 ataaaaattt aggatgtcga ttgcagacaa aatctgcctg atcaacaccc tgttttttat
     3481 tgttccaagt tatcgagcca gtcatcgaaa ctcttcttag agatgcgata ctttccgcca
     3541 tccaactgga tccaccggaa ttcctttttc tttaaaaggt tataaatagt aggtctgctg
     3601 actcctaaga tttcctgtaa ctcttgaact gtataacatc ttttttctga catttcttta
     3661 tcctcttttc tttgaaatat gaaagaaaaa ttatcccttc atataacgaa acgctcagag
     3721 catgttttac agtggtcaaa agcaaatttt tttacttttt ttcttgcgag tttttttaat
     3781 gcaactcgta agaaactcgt aacattagat ttttacattt ttcatgaaat taagtaaaga
     3841 aaaagagcat atggaattga atccatacac tctatgatta ctgaaacttt atttcatttt
     3901 taattcaaca aacttgaatt tatatatgtc tttgcaaata taccatatct attagctgta
     3961 caccgccctc ataaattgtg tggtcataat tgtcagtaaa aaaattggga atcttgtgag
     4021 aacgaacaaa tccacatttt tcataaaatg gtatcgtcaa tggactgtca cctgttccaa
     4081 cttgcaaaac agaatattca tctgcatatt tactggcaag aaaatcaatt agtgctttgc
     4141 catagccctt tccctggttt tccggatcga ctgcgatatt cttgatttca agtattccgt
     4201 taccttcatc ggtgacaaca cattcagctt ttacatcatt atcttcaagc acatacatag
     4261 ttcctttttc aagataacga tcaaccatgc tctcctgttc atcagctaat aacaataatg
     4321 atataaactg ctttttattt ttgttaactt ctcgaatttt catacaactt gttactccat
     4381 caattgccat ctaatttaat tcatcaaact tgaagttgta ggtttctttg ctattatatc
     4441 tttaaaattc gttttgcttt cgcattaaca aattggataa tcgggcctga aatgataact
     4501 gtaatgattg tgcatatgcc aaacttcccg ccaagcaaaa cacctattat cacaaccaga
     4561 atatctaatg ctattcgaac aattttaact tgccagttgt tcttttctgc caaggcaaaa
     4621 gtaactgctt cataagagcc acgaccaagt gaggcagacg catatagtcc ggtcccgaca
     4681 gcaaacaaaa taacacccag caacatgata aagaagttga accatcgata tgtactgtag
     4741 acatggcagg tggcaaatac atctacacag gtgctgtata caatttgata tagcaccgtc
     4801 ccaatatgga tttgactttt atcgtaaatt aatgcaaaca aaatcatccc cactgctaca
     4861 acaaaagatg ccataccgat gctcaagtga aacgtttcag cgataccctg ccatagcact
     4921 gcgagcgtgg cgccaccaaa tcctgcatac agtgcaagtg taatgccata ggctgcaaca
     4981 atggaaccta tcacaataat tatcaatttc tttaataagt cccgcaatag caaggattcc
     5041 cttttgtgct tatcaaacat cataattcct ctattctaca aattccgatt ttaatgtctc
     5101 tattatacca taatgatact attataaaaa aggaaaaaga gctccttcga gctcttttga
     5161 ttcagttctg taaacttgaa tttgacttgc ctattttctt aaaatctcat gtggagcttc
     5221 tatttcattt gccaaggtat gctctgttaa ttctgacatc aatttcaatt ttttattaat
     5281 caatggtcgc atacaattag gaacatgttc ctgatgcgct ctgtggattg ctacacattc
     5341 cttacagttt ccgtgataac gacaggcttt caggcaagga cagtgatctt tgtctttata
     5401 ctccttacga aattccgctg caaattcttc ttgcagtctc agtccctcga cacggtttcc
     5461 cttatgaaat tctaccattg catccagttc tttctggttc ccttcaatct tcatgttatt
     5521 atagcgcctc catttcaact attcttcatt ttctgataaa ttccgatttc tattttcgtt
     5581 tccatagcat agtgtactct ttttcaccag tagtttcatc caagccttca tattgaataa
     5641 tgaacccttc tctttggtaa aaagaaattg ctctggcatt cttctggtat acatttaatc
     5701 gtaagctaac ttttttatcc ttaacataat ctaataaaag cttacctatg ccacatgact
     5761 gcatttcatc ggagacaaaa ataccttcta tatatttatc atttagtcct acaaatcctt
     5821 gtatcatttt atctgcttca aacacataaa cttcgtattg tgacatcatt tcttttacta
     5881 attcataatt acttttccag tattgattgg aaataaaata atgggctttc agatttgtct
     5941 ttaaccatat gtcagcaatt ctatcgatat ctccgttcag caactttcta atcataacaa
     6001 atattctcca caactacatc ctttatgctt ttctcttttt tccattctat cacaagctca
     6061 ccattaatca tcaatttttt gatatttttt ctttttcccc actgtaaaac agcctctgag
     6121 cgtttcgtta tatagaggga tacaaataag agcaagatcc acccaggtat taccgtatcg
     6181 ccattttatg gctacggcat acctccgggt aagtctcttg atggggattc cgattcccca
     6241 taccctcgta cagacatcaa agatatctgt tggctctcta tcaaagatag tcgcagcact
     6301 ttatataacc ggaagggaca gccggttaaa aagtgtaatc gcacatccaa gatgtcttat
     6361 caaaaaagaa ggaggactat ggcaccaaag aagaaagaaa agaatctcaa aaggagtaac
     6421 atcatcacat taaaattaac ggatattgaa ttggcagtat taaatgaagc cgctgacgtt
     6481 acaggacttt ctcgttctga atatgtgaga aaactactac ttgaaaagca aatcaatcat
     6541 cagattgaag tggttgcaga catgaatgat ctcagaaaac tggtcagtga atatggaaaa
     6601 attggatcga atctcaatca gattgccaag cattttaaca gcggtggcag tcagtcacgt
     6661 gctatagaaa atgaaatcca tcagtgcatc acggacttat tcctattgag aaaagaggta
     6721 ctgaaactgg caggtggtat gaatggcaat cgtaaaacac attaaaagca gaaatgcaaa
     6781 ttactcagct gctatcaatt accttctgtt tgaacatgat gaaaaaaccg ggaaaaagat
     6841 tgtagacgaa tccggacgaa gcatcatgcg aaaagagttt tatatggatg ggctgaactg
     6901 tgatccgatg tcttttgaca aggaatgtga actgacaaat gctcattttc acaaaaataa
     6961 gaaacgtgca gatatcaaaa gtcaccacta cattatcagc tacgatccag ccgatgttac
     7021 agaaaatgga cttaccggac caatagcaca agcaatcagt ttggaacttg caaagcagat
     7081 gtttcctgga tatcaggcac tggtggttac tcatactgac ggtcacaatg agtccggaaa
     7141 tatccatacc cacatcgtca taaacagtgt gaggaagact gcagtggaaa ggcagccgta
     7201 tatggataag ccacatgagg aagctgccgg ttacaagcat cgttccaccg ataaattcat
     7261 gaacgcattc aagaaaacag tcatggaacg gtgtcaacaa gaaggatttc accagataga
     7321 tcttcttgtt ccagctgaaa gaaaaactac tcaaaaagaa tatatagcac agaaacatgg
     7381 tcagcaaaaa ctggatgaaa tcaatcagaa aattatcgaa gatggtctca aaccaacatc
     7441 cactgtattc cttacgcaga aagaatattt gcgaaatgcg attgatgaat gtgcttccac
     7501 atccaatagt tttgatgaat tccaatccaa acttctggaa caatttcaaa tctctgtaat
     7561 tgagcatcgt ggcagataca gctatcttca tcctgatcga cagaagcgga ttactgaacg
     7621 ttcactggga acacgatatg gaaaagaaca cctgaaacag accttcttac gcaaggatcc
     7681 attggccatt ctctacgtca gatctcacct gcgcctggtt gtaaatctcc agacaaatgt
     7741 gaaagcaatg cagagcccgg cttatgctca tcgggtaaaa ctttctaacc tgcagcaaat
     7801 ggcaaatacc attatctacg tgcaggaaca tggatttgat acgcagtcag atttgaaaaa
     7861 tacactggtt gcatcaaagc aggaattgaa agaaatgcag acacagtttg ctcagcatcg
     7921 ttccgatcta aggatcctca acgatcagat tcgttatacc ggtcagtact atgcaaacaa
     7981 ggaagtttat tcccagtttt caaaagcaaa gtacaaagga aagtaccgaa aagaacatgc
     8041 gaaggaaatt cagaaatatg aagaagccag aaattggctg aaatcctttt atcaggatgg
     8101 aaatatgaca agcctaaaaa ccttgacttt gcaaaaagaa aaactgcaac agcagatagc
     8161 ttccgaagaa gaagcaataa gcagcttgaa agaaaaatta aaagatctgg atactgccga
     8221 tcagaatgtt gatgccattc ttcagatgca gataccagaa ccagtaagat caaaaaacaa
     8281 agatctcgaa cgataactat cacaaaacaa aggaggaact atcacatgac acaagaagaa
     8341 tttaatattg tatttgaact tcagatgaga aagtgtgccg atattctggc acataaaaag
     8401 aaagaatata ccggtgacaa tattgaccgc ctcagtgcat tcaagattgc tgccgcctta
     8461 caaaactgcg atccaaaagc agcactggcc ggtatgatgt cgaaacatgt cgtatccctt
     8521 tacgatatgt gttattccac tctgttacat tttgacatgg aacagtggga tgaaaaaatc
     8581 acagactgca tcaattatct gatcctttta aaagctctgg taaaggagga acaggcctat
     8641 ggatcacatt gaaacagcta tcttaaactg ctatggaatc cgggaagcag aacagaatat
     8701 ggtctttgct gccagactca cacaacacgg tcatacgatc cagaacatgg cagatctgat
     8761 ggatctttac cgtcaatcct acagtcagaa gactgtagaa aacattgcag ggcttccgca
     8821 tccaaccgtg cagaaattca tggtcattac cgtagctgtt gttggtgcaa gcagacgctt
     8881 cctggcacag atcacaagac atcagaatga agtaaagtac atgagtgcat ctctgcagta
     8941 cagcaattat tccggtcatg ctgcatttgc tattccatat ggaatcatga aagcagataa
     9001 agaaatccag gatatttaca agaaaagctg tcagtcagat ctggatcatt atgcagagct
     9061 ttgtgcctta ggcattgatc atgattcagc cggatatgcc acacctcagg gacttcgaaa
     9121 cgtactgatc atcagcgcga caccttacca gtggaagcat atgattggtc agagaacctg
     9181 cagaaggaat acggatgaaa ccaggattgt gatgctctat atctggcaaa gattgtacaa
     9241 attaagcccg attctttttg caccagatct gaccggtcca ttctgtcaga gaggaagctg
     9301 catggaaaaa cagatgtcct gtcagaatcc catttcaaaa ctttggatgc ctgcagatat
     9361 cttaaaaaca gattatccat tgctgatccg gaaggagatg agcagccata aagattaaac
     9421 tgattgactt tggtctgaaa gcagatcatc atccattccg gccacatgaa aatgatgccg
     9481 gtgctgatgt attcatgcct tatgattgcg tattaaaacc aggcgaggtt gcaagaattc
     9541 cgcttggatt cggtctcatc atcccagatg gatttgccgg atatgtcttt ccacgaagca
     9601 gcatggcagc aaaaggactg gtatgtgaac ttccaccgat tgactccggt tatcgtggtg
     9661 aaatccatgc cattataagc aacgtgagca catcttctca gaccattcat aaagacacac
     9721 gcgtcggtca gctggtgatt acaccggtcg tgatcgcaga ttttgtcctg gaccttggtg
     9781 aagaacgagg aactggggca ttcggaagca caggagaata atactatgat tacatttgga
     9841 agaaaattaa aacacttaag acaaaaaaat catctcaccc aaaaagaact tggcatggct
     9901 gttggatttc ccgacagctg tgctgatgtc cggattgctc agtatgagag tgatgtccga
     9961 acaccgaaag aggatcttat gaagctcttc gcatcaacac tcggtgttcc ggttgaactc
    10021 tttaccgtac cggtactctc agaacccagg gagtatgagg cggcggagta ttggaggtat
    10081 gagttagggg cggaactaga ttaagtgtcg tatactgtaa tgaggcaacg gattatccgc
    10141 tgcctctctt ttatcatttt aggggtaata attgaaaata acctgtattg agcaatcctc
    10201 tttttctgcg ctttatctac atatctatat atttcacttt atttctgttc catcgataag
    10261 aagcacatat ttatccggat tatgaacaag atcataatct tttccatatt caatcggtct
    10321 aaattctatt tgcataatgg attcgccatt ttcgatatct tctttccaag aatatacggt
    10381 catatcaagg ctggttgcat atccatgatc tgtagaaaat tttattgaat gaaatgaatt
    10441 ctctttgtac atttttaaaa gcagtcttgc aaatgcttct ttatcagaaa tattttttct
    10501 gttagcaact actgtaaaat tttcatctct attcatagaa aaactgccaa ctacatctgg
    10561 ctcaccttct ttatacttta ataagctttt tccaattatc attccaacaa taatcgaaaa
    10621 aacgatagca acaaatacaa gtgttatatt atttttcttc attttattaa gttccttaga
    10681 attatatagt tgaattaaat ctgtatttca aataaaacgc ctacaaagtg ggcgttttat
    10741 tatcttaata ctatttaatt tttttcattt cttcaacaaa ctgttcttgt gtaattctcg
    10801 catttaatac attttttcct aaaaacaatt catctttatc acatgtagca aaacatgatt
    10861 ttacccaatt aactttttta tttaatttta aataatgtat gaaaccagat aaggagaaaa
    10921 cgtaaattgt gttaatgata gcagacatga gtatggagtg aatatcttat ttggaggaaa
    10981 aacaaatggt acaatcaatc tttgaggaaa tgggcggcag atacgaacgg caaggcgaat
    11041 acattttacc ctgccttacc ataccacccg aaaaggaaca gtcgatagac ttattcggac
    11101 ggcggcactt ggactatctg cgggagtacc gcaaaattac atacaccaat cttctcacaa
    11161 gcggcaggct caatgcttac cttgccgaca ttgacagaca ggcacaggaa cactttgaac
    11221 ggctcataga gggcatgaag caagcacagg gcataacgga atgcctaaag gaagaaaacg
    11281 ccttagaatg gactggaaga acgaataaca taagggcttg tgcgagggag attgtggaaa
    11341 aggaaattat ttttgcataa acagatgatt agtggcaggg ggaaatcctg ccgctttttc
    11401 tgctttagtt tgtcagcttg acaaataaag ggttaaggaa tataattaga ttcagtatta
    11461 tacaaggagt taataaatat gcggcaaggt attcttaaat aaactgtcaa tttgatagtg
    11521 ggaacaaaaa gtagcagtcc cgtttcactt ttaatatggg gcttagtttt ttgtacccag
    11581 tttaagaata cttttatcat gtaattttat atgcccgaaa acatataagt gttttggggc
    11641 tattggagtt atttacccag tgataggagt atttatcact gggtattttt atgccctttt
    11701 ttgggtgttg ataggaggaa aatcacatga aaataattaa cttaggcatt ctggctcacg
    11761 ttgacgcagg aaagacaaca ttaacggaga gtttattgta taccagtggt gcaattgcag
    11821 aaccagggag cgtagataaa ggcacaacaa ggacagatac aatgaatttg gagcgtcaaa
    11881 ggggaatcac tatccagaca gcagtgacat cttttcagtg ggaggatgta aaagtcaaca
    11941 ttatagatac gccaggccat atggattttt tggcggaagt ataccgttct ttatccgtat
    12001 tagacggagc agtattatta gtttctgcaa aggatggcat acaggcacag acccgtatac
    12061 tgtttcatgc actacagaca atgaagattc cgacaatttt tttcatcaat aaaattgacc
    12121 aagaggggat tgatttgcca atggtatatc aagaaatgaa agcaaagctt tcttcggaaa
    12181 ttatagtgaa gcaaaaggtt gggcagcatc ctcatataaa tgtaacggac aatgacgata
    12241 tggaacagtg ggatgcggta attatgggaa acgatgaact attagagaaa tatatgtcag
    12301 ggaaaccgtt taaaatgtca gaactggaac aggaagaaaa caggagattc caaaacggaa
    12361 cgttatttcc cgtttatcac ggaagcgcta aaaacaatct ggggattcgg cagcttatag
    12421 aagtgattgc cagtaagttt tattcatcaa cgcctgaagg tcaatctgaa ctatgcgggc
    12481 aggtttttaa gattgaatat tcagagaaaa ggcggcgttt tgtttatgtg cgtatatata
    12541 gcggaacatt gcatttgagg gatgttatta aaatatctga aaaagagaaa ataaaaatca
    12601 cagagatgtg tgttccgaca aacggtgaat tatgttcatc cgatacagcc tgctctggtg
    12661 atattgtaat tttaccaaat gatgttttgc agctaaacag tattttgggg aacgaaatgc
    12721 tgttgccgca gagaacattt attgaaaatc ctctccctat gctccaaaca acgattgcag
    12781 caaagaaatc tgaacagcgg gaaatattgc ttggggcact tacagaaatt tcagatggcg
    12841 accctctttt aaaatattat gtggatacta caacacatga gattatactt tcttttttgg
    12901 ggaaagtgca gatggaagtc atttgtgcca tccttgagga aaaatatcat gtggaggcag
    12961 aaataaaaga gcctactgtt atatatatgg aaagaccgct tagaaaagca gaatatacca
    13021 tccacataga agtcccgcca aatcctttct gggcttctgt cgggttgtcc atagagccgc
    13081 tccctattgg aagtggagtg cagtatgaaa gcagagtttc acttggatat ttaaaccaat
    13141 cgttccaaaa tgcggttatg gagggggttc tttatggctg cgagcagggg ctgtatggat
    13201 ggaaagtgac agactgtaaa atctgttttg aatatggatt gtattatagt cctgtaagta
    13261 cccccgcaga ctttcggctg ctttccccta tcgtattgga gcaggcttta aaaaaagcag
    13321 ggacagaact attagagcca tatctccact ttgaaattta tgcaccgcag gaatatctct
    13381 cacgggcgta tcatgatgct ccaaggtatt gtgcagatat tgtaagtact cagataaaga
    13441 atgacgaggt cattctgaaa ggagaaatcc ctgctagatg tattcaagaa tacaggaacg
    13501 atttaactta tttcacaaat gggcagggag tctgcttgac agagttaaaa ggataccagc
    13561 cagctactgg taaacttatt tgccaacccc gccgcccgaa tagccgtata gataaggttc
    13621 ggcatatgtt ccacaagtta gcctaacagc ttgcataagt cgtataaaat gagatttgaa
    13681 aggattagaa gctaattatg atgaaatgcg aatggatatt atgtcctgtt tgtgggagca
    13741 aaacccgtaa taaaattagg aaggacactg ttttgaagaa ttatcccctt tattgtccaa
    13801 aatgcagaca agaaagattg attaaagttg acaacttgaa gataactgtc atcaaagagc
    13861 cagacgctta agacgcagag ccgatgaaat tgtggaacaa ttcacgaatc atcggctctt
    13921 tttgtttcgt atttgaaaga acaaactcac caaataaaaa aaacgatatt cgggtgggtt
    13981 attttgttat accctaaatt accctctgaa tttgttttta aatttggagg gtttttatgt
    14041 tccttttttc gggcggttgc ccatctgctt atataaagca aagtttattt atacatagca
    14101 catcagggaa tggcgggaag ccagttaaaa aaatccctgc cagtgcaacg gtacttccca
    14161 ccatgaaggt agaagtacaa tctccataca acagaattag tatttcccat aaccgtaagc
    14221 agtagctaaa tgtattgaca gttcacattc atagccggaa tatcccgctt gcggagcata
    14281 gctttttttg accgcaaagc attaggcggg ttacagtaaa taaaaatgga cacggcgata
    14341 cctccccgat accgccgtat ccttaaaaaa gggcgacttt aatacactac ccgcaatcca
    14401 ttctataata gggaacagcg gcttttgcgc aatattaaat aaaaaagccg ataacacata
    14461 ggttttttga cctaatgcgt tatcggctct gcgtctatgc gtctggcact tttaatcatt
    14521 tttttttgaa tttattatat gtgttagcta actgtccaca agccgcgtta atctctctgc
    14581 catgagaaac tctcatagta acttcaagtc ctgcttgctc taattgatgt ttgaatgcaa
    14641 ctatttcccg tttctgtggt gctttaattc ttgaattgct tgttgggttg tattgtaaca
    14701 cgttaatcat aacttttttg ccccgaaacc attttgcaag ttgtcttaca tctgagggcc
    14761 ggtcatttat acccggtaaa agcaaatacg caaagacaat tttgcgatta tgcctttcag
    14821 aataggataa ggcttgctta acaacatctt caatagcata tatgcgcatg tgaggaataa
    14881 tacgatttct tgcagattgt gttgctgcgt gtaaagatat tgtcaactga attttaagat
    14941 gttcctcgcg caattttttt aattgatcga ccggaccaac tgttgatatg gtaatgccgt
    15001 cggttggaaa gttgagccca tatctatctc ggagaatatg gattgctttt atcaagttgt
    15061 cataattgaa taaaggctct cccataccca taaaaacgat acggtttact tttcgacgca
    15121 acaatataat ctgttgtacg atttctgacg atgttagatt acgaacaaag ccatttcgcc
    15181 cggactcaca aaaaatacaa ccaacaggac aaccgacttg tgtgctcacg caaacagttc
    15241 caccatctcg ccgcttgata aaaaccgttt caatgtattt gttgtctttc agttcgtaaa
    15301 catacttttc agtatcactg cttttgcaaa tattttttac caacattgat agattttttt
    15361 tgcgtggtaa ttgcttatat aattcttcat ataaggcttt tgcttcattc tcgccaataa
    15421 cttccgacat ttctttgtaa gtaaatccgt atggatcatt ccgtacttcc gcaggcgtat
    15481 atttaggtaa acgtttcatt tttatatcct ttcttctaaa taataaaagt ttgtttttct
    15541 gtatttttga ttacaatctc taatttttct acatcaatga tatgcgtcaa tttgcattta
    15601 gggcagaaaa gaggaaaatc ttttaataca gtattatgaa atacttgaac tctcgtcttt
    15661 ccgttacaaa tcggacattt tatccaatat tttttaagca ttatatttca ctcgtccttt
    15721 ttacacaaaa aaatgcaggt caatcctcaa catgagcatt gacctgcatt tataatgcac
    15781 agagcagtac aacaaaacta aggcatagct tgcactatgt ctatactata tctatacgtc
    15841 gttagttttt tgtatagcat ccgcaaaata agcatgacaa aaaagcccat gttgaaaatg
    15901 ggaaaatcct ttttttcaat gcttatctaa tacgcatgct atgcaacata aacgccgcct
    15961 ccttttacat aaattttatt ttatcagaaa atcagtctac tgtcaataca caacaggaag
    16021 tatttaacct aatgatatga attgtgtgga catatccaaa aagaaaggtg aactgtaaaa
    16081 tgtaacaggg tgaatgaaaa tggcaaaaag acccgtacca ttgtacgact ttaaggcttt
    16141 cggggcagct ataaaagccg cgagaaatga atacggcgag agccgcaaaa aggtaagcga
    16201 cgagttatat atttccccgc gctaccttgc gaatatcgag aacaagggac aacagccgag
    16261 tttacaggta ttctatgacc ttgtaacccg gtatcatatt tcggtagatc aatttttctt
    16321 cccgaacagc aatgcggaga aatccaccgg gcggcggcag cttgacgcgc tgctggacgg
    16381 tatgagcgat aaaggcatac ggattgtaac cgcaacagca agggagataa cggaagtcga
    16441 aaaagcagag gattaacctc acaatatgag aaatcgggag attgcagcgc atggcggctg
    16501 caatcttttt ttgcgtccaa aatcaaagga acgcgcaaca aatgtagtat accattcatc
    16561 cgtgttatct gcagaatatt ttgcgttatt taatattgaa tttcctgttt tatttatagt
    16621 tataatttct tgatctttgc cgttgatcat ttgcttgatt ctcccctgca tgaatttctc
    16681 atttgtcttg attagattct aattctttta atttcttttt catttcttca tattcatcga
    16741 aataagaaat taatgctctt tcaacagcaa ccgtttttgt atgtcctgca tctttacaaa
    16801 aattttctaa tcgctcataa ataggagttt caatacatac attaaggtat gttccattct
    16861 tttttggtct tgccattttt ttctccctgc atttaatact attacatgaa ttttcctcaa
    16921 ataattgtac cactgaaaac tacttaaatc aactattcac tacttgttat caaatatata
    16981 aaagataaaa tcaggttttg tactactaaa tgattttaaa caaaataagg cccaaaaggg
    17041 aactttccct tttgagccta tacactttat cagctaacat attttgcttt catttttcct
    17101 catggtcatg aggctttttt ctcttaaatc gcattctatg aatcctttga ttgttccttc
    17161 tgttcttcaa taattcgttc tgttgcttta tgaattctgt ccttagaata gggtggtctt
    17221 aaattcaatg acaaccggcc ctttttgatt atatacgttt cactgccatc ctccgaagat
    17281 cctttcaacc agcaatcatc cggatacttc tcagcgaatg cccgtaaccg tttctgcaag
    17341 ctctgattga aggtatacac atcatagaat ccgtcatctt cattggtcag aataatcgtt
    17401 tctttttcac actttaacct tcgcatattc tacccccgct ttctttccat ttcctgatcc
    17461 aggtatttgg gtatcggttt tccggaccgg cgagcaatgg caatctgttt ctgatgcaga
    17521 cgtttgatca cggatcttcg tttcttagat tttccatcct gttgatttcg ggaggtctga
    17581 ttgttgctgc tagcatcaga ggtcttttcc tgattcttct tctgattatt caccagaccg
    17641 tccaccatat cataattggc ttcggtacca gattctctgc ttcgttcata agtgccgttc
    17701 tggtagaatt tctggtaatg ttccagacgg attttaccat cttgttttag ctgttcgacc
    17761 ggatttagcg gtacttgctg ttggatgtaa tcatgaatct tttgttttgt cttttcatcg
    17821 aatttcttac attcttcgac aaccattttt ccataggcat ccaggataac accctgggcc
    17881 tgatctcggt atacctgatg ttccatcaaa taaaactgtt ttccatcaat aatgatggtg
    17941 tctgtggcaa tccagtttcc ttttttccca tcgatctgat aattctcagt ttccatagtg
    18001 atcagtgcac cggatgtatt gatacgaatg aatccggcca gatactgtgg atagttttca
    18061 tctacatagt agcaactgat ttctccgttc ttgttcaata cgagcacgtc actgacttcg
    18121 cattgctttt tcattcgttt ccagatgtca gcgacttttt cattttcctg catttcatga
    18181 atcgagacta atcggtaatt ttcgacagta atcgacacat tctgctgtct tgcctcttga
    18241 tatggcagat gccacagtgc ttttcctgct gtctgctgat ctactcggta gactgcaaat
    18301 tgattaagct tcataggcat cgttctccaa gttattcaga taataattca gatccagaga
    18361 atagtagtat ttgtcttcga tctgctgtaa ttttccaact gtagaattga tgatctcaat
    18421 catttcatca ttctcaggat cactttcttc ctgttccata acttccaaag cttctttcag
    18481 tgtttggatt gtttcttcct ttgtgtgctg ctggaagata gcagtaatag tcagttcgtt
    18541 ttcttccagg tttacatttc tcataggctc atttcccccc ttttcttttt cggtattggt
    18601 ttcatctgta tattcagctc cttctcgttt ttttctttgc ttatattttt ttcgttatcc
    18661 actttcttat tggattccag aggattttcc acatttggat gtctttcttc caagtacttt
    18721 tccacacgac tgattgcatt ttgcacataa gaattttctc taaatccagg aatcgaattc
    18781 aaaaattctt tctgtatttt tccttcgatc atcagactct gcattccttc ataatcactt
    18841 ccgtctttca gatcaaagcc aacacatttc agtccatgca tacgttctga tgggattttc
    18901 tcataagctt ccaaggcttc cggtaatgtc aggtcataat gtacttcacc catcacagga
    18961 aattcagcac attcagccgc ataaaagctg atacatgtaa gatcattttc ataatccaca
    19021 ttttctattt ccgggacaat atcgagtatt ttttctcttt gtactgcaaa gtctggaagt
    19081 tctgcaaatc caaatcgatc cacgtaatat gcctgcatat ccccaccacg gtttgtaatg
    19141 ataacatcac taaccgacat agaatgtgct ttataatctg ccggtggatt atcgttgaat
    19201 acggcataca aatcatccag cttttcattt tcatgtaatc tgccagaata gacacattta
    19261 taatttgctg catcgattgt aattccatct tctttgacca ttgccatatt cataaataaa
    19321 tgttgttttc caggtgtgtc ttcatccacg tggtaaatcg catagcggtc accattacct
    19381 ctgaacattt cttcctctag ggtataatca aacttaaatg gatacaaagc ccgatcaact
    19441 ctttccgaaa tatccgttcc ttctgcaatc gtatcttcca gccagtcttt gatatctccc
    19501 catgattcaa actgcaagta tccggcaatt tcatgtgtcc catccggcgc cagtacaata
    19561 tgtcccggtt cgctttcccg ataatcatag cggtatccgg ctgcttccag tgcatctacc
    19621 agaatgccgt atttatcatg taattctgtt ttctgttttt cttcaagaat gatttccagc
    19681 tcttctgtaa gctgatcgat catttcaccg gctgtcttgc ggatcacatc catagatgct
    19741 ttcatttctt tcatttcccg gctgctgctc caacctgcaa tgtaagggaa actataatcc
    19801 gatgtatcca aaccaaagga agaacacaca cagtaagcaa cggattcagc ctcaacctct
    19861 tttgtcaatc ggtctttttc tacaccaagg ctttccatga tctccctgtc atgcaatttt
    19921 gcatggactg tttcatgaat agcagtcttt aaggtctggc tttcactgag tccttttttg
    19981 atcacaattt ccttatctgc attatgataa tatccattag cattgtcatc gatctcatcg
    20041 aatcgtatcg gtactgggga tattttctga atagcctgca tgaaagaatc aaaatcctgt
    20101 acagctgcag tcagtaattc tggtgccagt gtctggatcg gttctccgga tgtctgagca
    20161 atatcaaata ccgtaactgc tttaaaatgc ggaactgtaa cttccacctg ttcagtctta
    20221 ggttttccat cgcttcccat gatcggtcgc tgattttcat ccagaacctc tttttccttc
    20281 attttcttat atggtgccgg ggcaatgatt gtaattcctt tttcaccttt catgacctgt
    20341 ctacccatgg actgccagtt tttgtagctg gtaacaagtg tggcatccgg tcgctgcata
    20401 gcgatcagca ttgtattatt aaaagaataa ttgtgaaact ttgccatggt tttaagaaat
    20461 tcctgatagc ggttacttgt aaatagttct tccacaccgg attccagtga ctgcataatg
    20521 ctgtccatat cttttcccgg aaccggcagt ggaatagtag tagttttgtt ttgttctgtc
    20581 ataatactcc tttccaaaaa cgccccacga cattgtgttt atgccgcagg gctttttatt
    20641 agttgacgag atgattattt tttattaaag ttccatatcg tgcttctttg ttttcggttt
    20701 ctgatccggc tgttcttttc ctgctttctc tgtttttgca gcctgcgctt ctttttcttt
    20761 ctgacgttct gtaaatctgt cggctttttc aaagacgtga tcctttgtgt caaagtgata
    20821 tacatcattg gtaaggcgtt ctgctggtgc tacctgagtc gcattgactt cttttaccat
    20881 atctcttaac atttcagcat ccacttgccc gtcatccggt aaaatcagca tttcatgaat
    20941 ggatgatggc aaaataaaga aatcatttcc cagaagttcc cccatgttat ccatgaattc
    21001 cggataaaag atcacaccgg caccatcaac tctttctgta tttgtaacaa caaagaatgt
    21061 cggcatctca cttgattcct gcaatgtttc ctgcagcatt tcacgttcat ccggtgtcag
    21121 catgagaata tttttctgat acatttcatc tatcaatgca cctatacttg atacctccgg
    21181 gaccataact cgtggtgaac ttttcatagc atcttcatga agctgttctg ctgagattcc
    21241 atactgttca agcagatcat tcttgataaa catggaactt aatccattct catccttgtc
    21301 tactgccaca tgataggtaa ttgcgaggtc ttctttcagc tggtgtggag cattttcgag
    21361 gacttcctta tttgcttcgg ctgatgatac acggataaac agcttgtcct tcacatcttc
    21421 ataattaaaa atagctttca gatcaacctg tatcggtgcc tcaataacta tatctgcaat
    21481 ctttctgcat acagtttcca ttgttacgcc aggctgtgct ttatatgctt catacaactg
    21541 attaagattg atcgtcgggg taagcatctc accttctttt ctcaccatca atcccgtata
    21601 ggcacggttc agttgctgac actccatcgt tgatacttct acattctcat actcctctgg
    21661 taaaaagagt ttgatattat cctttacttc acttacaaat tcgttaaaat tcattcttcg
    21721 tttcctcctc taatctgttt ttttatttct ttttgctttt gttttttgat ttctttttgg
    21781 gaaaggataa agaaaaattc acctttccgg tttcatctgt atccatatgg agatctgcct
    21841 caaagtacat atttttcttt ctggaataca ggtctttcac atgcacactt ccgtttttca
    21901 gaagttctgc agccatcttt ttatccatgg ttttttccat gctctgcaga tagcggttat
    21961 ctttccagag cgcaaagtga caatcatggt tgctgcaata gaagttgggt ttgctttcat
    22021 ataccaggct tccacatacc ggacatgttc caatgctttc tctggtctga aatcttcttg
    22081 tttcttcttc ggaaatcgca tcgcatccat tcagcatcat ggtcagcatg tttttgatcc
    22141 cggtcataaa ctgttccggt gcaatctctc catgctccat caagagcagc tggttttccc
    22201 attctgcagt catacttgca gatttcagga agtccggcag gatctccaca aggacttttc
    22261 catcctctgt tggaagaatc tgttttcctt ttcgggtggc atactgggaa tagatcagtt
    22321 tttcgatgat accggctctt gttgccggag ttcctaatcc tttcttttct gtatcttcat
    22381 cgaattcctt atttccagca gtttccattg ccgcaaggag cgtatcttca ctgtatggtt
    22441 ttggcggtga tgtgaaatgt tctgtctttt ctgcagctac agcatagaaa gtctgtccct
    22501 gggttacttt cgggatcttc tctttcattt cctgatccgg atctacgatt gccatgcggt
    22561 ccttattctt gaagcagttt tcaaagagtt tccatccatc ctgcaacaca gtttttcctt
    22621 ttgctttgaa gatttctccc tggcattcca cttcaatctc tgtttcctgg taaacgtgct
    22681 ccttactcat tgccatgacc gtgtgaactg caatcaggaa aagaatcttt tcttcccaag
    22741 atttcaattc atccagatgg caggatgaaa gctccatcgt tgggatgatt gcatggtgat
    22801 ctgtcacttt gctgttattc atgactttct tcacatccgg ctgttccggc tgatcaaaag
    22861 gacctgtcag ttgatatttc tcataaatct gacgaaccac atttcttgcg gtctgctcca
    22921 tatcttcggt cagatactgg ctgtccgttc ttggataagt gatcagtttc ttttcataca
    22981 ggttctgagc ggtatccagt gtctgtttgg ctgtcattcc gtagatacgg tttgcttctc
    23041 tctgcagtgt ggtcagatca taaagctttg gtgcttttac tttcttttcc gtttctttta
    23101 ctgctgtgac aatagcttca cttccttggc atctgcttct taactgttcc gcctcatccg
    23161 gatcaaagat ttttggcttt acagccggaa ttccatcaca atcgagttcc acattgaaat
    23221 acttttcttt ctggaaattg ctgatctgtc cggcacgttc caccaacatg gcaagtgtcg
    23281 gtgtctgaac ccttccaacg gtcagctttt tgaagtactt tgtggtgtaa gctctggttg
    23341 cattcattcc taccagccag tcagcctgag aacggcatac agcagcttcg gccagatgtc
    23401 ggtattcctc tgcggatctc agatgctgca ttccatcaag gattgctgaa tcttccagag
    23461 aactgatcca taatcgtttc accggctttt tacttccgga taagtcatag acatgtttga
    23521 agattaattc tccttcacgt ccggcatcac aggcatttac gacgtattca atttccggac
    23581 tgttgagcag tctttttaag atatagaact gatctttctt atcttctgag actgtaactt
    23641 tccagtcttt cgggatgatc gggagatctt catatctcca ctggttaaat ttctcatcgt
    23701 aagcatccgg tgaaacatat tcggccagat gtccgaagca ccagctgacc atacagtcgg
    23761 ttccttgtaa atatccgtct tctcgttcct gtgctccaat cacttctgcg attgctcttg
    23821 atacacttgg tttttctgca attactaaat acaagatgta ttacctcctt catataacga
    23881 aacggagaga gcatgtttta cagccccctc cgctaaaaaa gtttatttat ttttcatttt
    23941 cttcaaaatc ttcgtcttca gactcttcct catccggaac ttcttccagt ccacctgttt
    24001 ccaaaccttc cggctgatca tcctcatctt cctctttttt aggtttatag atcttgaagt
    24061 agtagtaagc tgccacgccg ccgagagcca aaatcaggat tgttgccatt gcacccatat
    24121 tggtttttgc agatgatgtt ttctcaggat caacagtagc ttccttgtct acatcctcat
    24181 tatttgtctc atccagcaca accttcgatg tatccggctg tggtgttaca acagcagctg
    24241 tactgtcttt atccagaaac tcggacagat cattctcatc aatctgagat aacatataga
    24301 cattctggga tgtggcactg cggtcgatca cgatatagaa agtgttgtta ttcttcgttg
    24361 taaccgtaag aaattccttt gtggaatcat cggtaatgtc atc
//
LOCUS       DAFENC010000173        24403 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.guided.039, whole genome shotgun sequence.
ACCESSION   DAFENC010000173
VERSION     DAFENC010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24403
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.guided.039"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(621..812)
                     /locus_tag="LP493_003015"
                     /pseudo
     CDS             complement(621..812)
                     /locus_tag="LP493_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008791949.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein Fic"
     gene            complement(974..2365)
                     /locus_tag="LP493_003016"
     CDS             complement(974..2365)
                     /locus_tag="LP493_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008816766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBL2135080.1"
                     /translation="MASIRERNGKFNVIYSYTNEKGERKQKWETYETKAEAKRRKKEI
                     EYKKEMGSFVVRKCKTLDELITEYVALYGKENWALSTYEGNVSLINNYILPIIGDTKL
                     SEINTRFIERYYQSLLKRRAVINPLNKTSRNEFVSSSTVRDINKLLRNCFEQAVKWEL
                     MEKNPCTHATVPKHKSQKRDIWTADTLMYALSVCEDERLKLAINLSFSCSLRLGELLG
                     LTWDCVDISHEAIEENRAYVFINKESQRIRKESLNALDGKDVLLVFPTNHKKNSTVRI
                     LKTPKTESSVRKIFLPKSVANMLVDWKAEQDEMKEILGDEYMDYNLVMASTFGLPLGD
                     GAIRGPLKKLIEDYNLPPVVFHSFRHSSVTYKLKLNGGDIKAVQGDSGHAQVNMVTDV
                     YSHILDDDRRKNAELFEEAFYEKKNLDPQMHVQQENNNTTVADEVDPELLAKVLANPE
                     MRALLNSLAKTMK"
     gene            complement(2367..3356)
                     /locus_tag="LP493_003017"
     CDS             complement(2367..3356)
                     /locus_tag="LP493_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005423640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2135081.1"
                     /translation="MATAIMKQKEVPEMDDVEEIISKISEDSPYKRRPTQKRTWMTVP
                     EMGKLLGLKKTDRYWLVHKNVFESKEIAGKIRINIASFEKWYANQIKYHKVTGEEPGK
                     ELKSWSYSVKEVADLLGVDEYLVYDLLKKNQMEAVIVDYWKRIPKESFQNWYKSQSRY
                     RTKEDRKKDALLEDATITMPEMAQLLGTTRSAVYTILDNPKYSHFFEFIVIAEKKRIT
                     KESFRKFLEGQDRYKLDPSNDYEELAQEQNIALANFRRKKLSQTGIRGSNGNIKYLTF
                     DEASYLAKVSRSMINKWADKGKFTVIKVGSRVRIRRDEFEDWMEQRDLERSMQ"
     gene            complement(3477..3653)
                     /locus_tag="LP493_003018"
     CDS             complement(3477..3653)
                     /locus_tag="LP493_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005426062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2135082.1"
                     /translation="MSEKRCYTVQELQEILGVSRPTIYNLLKKKEFRWIQLDGGKYRI
                     SKKSFDDWLDNLEQ"
     gene            complement(3920..4363)
                     /locus_tag="LP493_003019"
     CDS             complement(3920..4363)
                     /locus_tag="LP493_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005719578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2135083.1"
                     /translation="MKIREVNKNKKQFISLLLLADEQESMVDRYLEKGTMYVLEDNDV
                     KAECVVTDEGNGILEIKNIAVDPENQGKGYGKALIDFLASKYADEYSVLQVGTGDSPL
                     TIPFYEKCGFVRSHKIPNFFTDNYDHTIYEGGVQLIDMVYLQRHI"
     gene            complement(4434..5060)
                     /locus_tag="LP493_003020"
     CDS             complement(4434..5060)
                     /locus_tag="LP493_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008789344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBL2135084.1"
                     /translation="MFDKHKRESLLLRDLLKKLIIIVIGSIVAAYGITLALYAGFGGA
                     TLAVLWQGIAETFHLSIGMASFVVAVGMILFALIYDKSQIHIGTVLYQIVYSTCVDVF
                     ATCHVYSTYRWFNFFIMLLGVILFAVGTGLYASASLGRGSYEAVTFALAEKNNWQVKI
                     VRIALDILVVIIGVLLGGKFGICTIITVIISGPIIQFVNAKAKRILKI"
     gene            complement(5191..5514)
                     /locus_tag="LP493_003021"
     CDS             complement(5191..5514)
                     /locus_tag="LP493_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004613237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS biosynthesis protein"
                     /protein_id="HBL2135085.1"
                     /translation="MKIEGNQKELDAMVEFHKGNRVEGLRLQEEFAAEFRKEYKDKDH
                     CPCLKACRYHGNCKECVAIHRAHQEHVPNCMRPLINKKLKLMSELTEHTLANEIEAPH
                     EILRK"
     gene            complement(5570..5995)
                     /locus_tag="LP493_003022"
     CDS             complement(5570..5995)
                     /locus_tag="LP493_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003864588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBL2135086.1"
                     /translation="MIRKLLNGDIDRIADIWLKTNLKAHYFISNQYWKSNYELVKEMM
                     SQYEVYVFEADKMIQGFVGLNDKYIEGIFVSDEMQSCGIGKLLLDYVKDKKVSLRLNV
                     YQKNARAISFYQREGFIIQYEGLDETTGEKEYTMLWKRK"
     gene            6379..6765
                     /gene="mobC"
                     /locus_tag="LP493_003023"
     CDS             6379..6765
                     /gene="mobC"
                     /locus_tag="LP493_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009263517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBL2135087.1"
                     /translation="MAPKKKEKNLKRSNIITLKLTDIELAVLNEAADVTGLSRSEYVR
                     KLLLEKQINHQIEVVADMNDLRKLVSEYGKIGSNLNQIAKHFNSGGSQSRAIENEIHQ
                     CITDLFLLRKEVLKLAGGMNGNRKTH"
     gene            6743..8296
                     /locus_tag="LP493_003024"
     CDS             6743..8296
                     /locus_tag="LP493_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004606465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBL2135088.1"
                     /translation="MAIVKHIKSRNANYSAAINYLLFEHDEKTGKKIVDESGRSIMRK
                     EFYMDGLNCDPMSFDKECELTNAHFHKNKKRADIKSHHYIISYDPADVTENGLTGPIA
                     QAISLELAKQMFPGYQALVVTHTDGHNESGNIHTHIVINSVRKTAVERQPYMDKPHEE
                     AAGYKHRSTDKFMNAFKKTVMERCQQEGFHQIDLLVPAERKTTQKEYIAQKHGQQKLD
                     EINQKIIEDGLKPTSTVFLTQKEYLRNAIDECASTSNSFDEFQSKLLEQFQISVIEHR
                     GRYSYLHPDRQKRITERSLGTRYGKEHLKQTFLRKDPLAILYVRSHLRLVVNLQTNVK
                     AMQSPAYAHRVKLSNLQQMANTIIYVQEHGFDTQSDLKNTLVASKQELKEMQTQFAQH
                     RSDLRILNDQIRYTGQYYANKEVYSQFSKAKYKGKYRKEHAKEIQKYEEARNWLKSFY
                     QDGNMTSLKTLTLQKEKLQQQIASEEEAISSLKEKLKDLDTADQNVDAILQMQIPEPV
                     RSKNKDLER"
     gene            8326..8652
                     /locus_tag="LP493_003025"
     CDS             8326..8652
                     /locus_tag="LP493_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009263519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2135089.1"
                     /translation="MTQEEFNIVFELQMRKCADILAHKKKEYTGDNIDRLSAFKIAAA
                     LQNCDPKAALAGMMSKHVVSLYDMCYSTLLHFDMEQWDEKITDCINYLILLKALVKEE
                     QAYGSH"
     gene            8639..9418
                     /locus_tag="LP493_003026"
     CDS             8639..9418
                     /locus_tag="LP493_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009267089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent thymidylate synthase"
                     /protein_id="HBL2135090.1"
                     /translation="MDHIETAILNCYGIREAEQNMVFAARLTQHGHTIQNMADLMDLY
                     RQSYSQKTVENIAGLPHPTVQKFMVITVAVVGASRRFLAQITRHQNEVKYMSASLQYS
                     NYSGHAAFAIPYGIMKADKEIQDIYKKSCQSDLDHYAELCALGIDHDSAGYATPQGLR
                     NVLIISATPYQWKHMIGQRTCRRNTDETRIVMLYIWQRLYKLSPILFAPDLTGPFCQR
                     GSCMEKQMSCQNPISKLWMPADILKTDYPLLIRKEMSSHKD"
     gene            9408..9821
                     /locus_tag="LP493_003027"
     CDS             9408..9821
                     /locus_tag="LP493_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008976873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyuridine 5'-triphosphate
                     nucleotidohydrolase"
                     /protein_id="HBL2135091.1"
                     /translation="MKIKLIDFGLKADHHPFRPHENDAGADVFMPYDCVLKPGEVARI
                     PLGFGLIIPDGFAGYVFPRSSMAAKGLVCELPPIDSGYRGEIHAIISNVSTSSQTIHK
                     DTRVGQLVITPVVIADFVLDLGEERGTGAFGSTGE"
     gene            9826..10104
                     /locus_tag="LP493_003028"
     CDS             9826..10104
                     /locus_tag="LP493_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006426622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2135092.1"
                     /translation="MITFGRKLKHLRQKNHLTQKELGMAVGFPDSCADVRIAQYESDV
                     RTPKEDLMKLFASTLGVPVELFTVPVLSEPREYEAAEYWRYELGAELD"
     gene            complement(10234..10662)
                     /locus_tag="LP493_003029"
     CDS             complement(10234..10662)
                     /locus_tag="LP493_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003864549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2135093.1"
                     /translation="MKKNNITLVFVAIVFSIIVGMIIGKSLLKYKEGEPDVVGSFSMN
                     RDENFTVVANRKNISDKEAFARLLLKMYKENSFHSIKFSTDHGYATSLDMTVYSWKED
                     IENGESIMQIEFRPIEYGKDYDLVHNPDKYVLLIDGTEIK"
     gene            10986..11360
                     /locus_tag="LP493_003030"
     CDS             10986..11360
                     /locus_tag="LP493_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001129922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TnpV protein"
                     /protein_id="HBL2135094.1"
                     /translation="MVQSIFEEMGGRYERQGEYILPCLTIPPEKEQSIDLFGRRHLDY
                     LREYRKITYTNLLTSGRLNAYLADIDRQAQEHFERLIEGMKQAQGITECLKEENALEW
                     TGRTNNIRACAREIVEKEIIFA"
     gene            11727..13646
                     /gene="tet(O)"
                     /locus_tag="LP493_003031"
     CDS             11727..13646
                     /gene="tet(O)"
                     /locus_tag="LP493_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032490535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(O)"
                     /protein_id="HBL2135095.1"
                     /translation="MKIINLGILAHVDAGKTTLTESLLYTSGAIAEPGSVDKGTTRTD
                     TMNLERQRGITIQTAVTSFQWEDVKVNIIDTPGHMDFLAEVYRSLSVLDGAVLLVSAK
                     DGIQAQTRILFHALQTMKIPTIFFINKIDQEGIDLPMVYQEMKAKLSSEIIVKQKVGQ
                     HPHINVTDNDDMDQWDAVIMGNDELLEKYMSGKPFKMSELEQEENRRFQNGTLFPVYH
                     GSAKNNLGIRQLIEVIASKFYSSTPEGQSELCGQVFKIEYSEKRRRFVYVRIYSGTLH
                     LRDVIKISEKEKIKITEMCVPTNGELCSSDTACSGDIVILPNDVLQLNSILGNEMLLP
                     QRTFIENPLPMLQTTIAAKKSEQREILLGALTEISDGDPLLKYYVDTTTHEIILSFLG
                     KVQMEVICAILEEKYHVEAEIKEPTVIYMERPLRKAEYTIHIEVPPNPFWASVGLSIE
                     PLPIGSGVQYESRVSLGYLNQSFQNAVMEGVLYGCEQGLYGWKVTDCKICFEYGLYYS
                     PVSTPADFRLLSPIVLEQALKKAGTELLEPYLHFEIYAPQEYLSRAYHDAPRYCADIV
                     STQIKNDEVILKGEIPARCIQEYRNDLTYFTNGQGVCLTELKGYQPATGKLICQPRRP
                     NSRIDKVRHMFHKLA"
     gene            13698..13871
                     /locus_tag="LP493_003032"
     CDS             13698..13871
                     /locus_tag="LP493_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002779755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HBL2135096.1"
                     /translation="MMKCEWILCPVCGSKTRNKIRKDTVLKNYPLYCPKCRQERLIKV
                     DNLKITVIKEPDA"
     gene            complement(14516..15499)
                     /locus_tag="LP493_003033"
     CDS             complement(14516..15499)
                     /locus_tag="LP493_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004607971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBL2135097.1"
                     /translation="MKRLPKYTPAEVRNDPYGFTYKEMSEVIGENEAKALYEELYKQL
                     PRKKNLSMLVKNICKSSDTEKYVYELKDNKYIETVFIKRRDGGTVCVSTQVGCPVGCI
                     FCESGRNGFVRNLTSSEIVQQIILLRRKVNRIVFMGMGEPLFNYDNLIKAIHILRDRY
                     GLNFPTDGITISTVGPVDQLKKLREEHLKIQLTISLHAATQSARNRIIPHMRIYAIED
                     VVKQALSYSERHNRKIVFAYLLLPGINDRPSDVRQLAKWFRGKKVMINVLQYNPTSNS
                     RIKAPQKREIVAFKHQLEQAGLEVTMRVSHGREINAACGQLANTYNKFKKK"
     gene            complement(15516..15701)
                     /locus_tag="LP493_003034"
     CDS             complement(15516..15701)
                     /locus_tag="LP493_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBL2135098.1"
                     /translation="MLKKYWIKCPICNGKTRVQVFHNTVLKDFPLFCPKCKLTHIIDV
                     EKLEIVIKNTEKQTFII"
     gene            16100..16456
                     /locus_tag="LP493_003035"
     CDS             16100..16456
                     /locus_tag="LP493_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBL2135099.1"
                     /translation="MAKRPVPLYDFKAFGAAIKAARNEYGESRKKVSDELYISPRYLA
                     NIENKGQQPSLQVFYDLVTRYHISVDQFFFPNSNAEKSTGRRQLDALLDGMSDKGIRI
                     VTATAREITEVEKAED"
     gene            complement(16459..16650)
                     /locus_tag="LP493_003036"
     CDS             complement(16459..16650)
                     /locus_tag="LP493_003036"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2135100.1"
                     /translation="MINGKDQEIITINKTGNSILNNAKYSADNTDEWYTTFVARSFDF
                     GRKKRLQPPCAAISRFLIL"
     gene            complement(16679..16876)
                     /locus_tag="LP493_003037"
     CDS             complement(16679..16876)
                     /locus_tag="LP493_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014073062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2135101.1"
                     /translation="MARPKKNGTYLNVCIETPIYERLENFCKDAGHTKTVAVERALIS
                     YFDEYEEMKKKLKELESNQDK"
     gene            complement(17136..17426)
                     /locus_tag="LP493_003038"
     CDS             complement(17136..17426)
                     /locus_tag="LP493_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015535390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HBL2135102.1"
                     /translation="MRRLKCEKETIILTNEDDGFYDVYTFNQSLQKRLRAFAEKYPDD
                     CWLKGSSEDGSETYIIKKGRLSLNLRPPYSKDRIHKATERIIEEQKEQSKDS"
     gene            complement(17430..18314)
                     /locus_tag="LP493_003039"
     CDS             complement(17430..18314)
                     /locus_tag="LP493_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4316 domain-containing protein"
                     /protein_id="HBL2135103.1"
                     /translation="MKLNQFAVYRVDQQTAGKALWHLPYQEARQQNVSITVENYRLVS
                     IHEMQENEKVADIWKRMKKQCEVSDVLVLNKNGEISCYYVDENYPQYLAGFIRINTSG
                     ALITMETENYQIDGKKGNWIATDTIIIDGKQFYLMEHQVYRDQAQGVILDAYGKMVVE
                     ECKKFDEKTKQKIHDYIQQQVPLNPVEQLKQDGKIRLEHYQKFYQNGTYERSRESGTE
                     ANYDMVDGLVNNQKKNQEKTSDASSNNQTSRNQQDGKSKKRRSVIKRLHQKQIAIARR
                     SGKPIPKYLDQEMERKRG"
     gene            complement(18304..18564)
                     /locus_tag="LP493_003040"
     CDS             complement(18304..18564)
                     /locus_tag="LP493_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005423594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HBL2135104.1"
                     /translation="MRNVNLEENELTITAIFQQHTKEETIQTLKEALEVMEQEESDPE
                     NDEMIEIINSTVGKLQQIEDKYYYSLDLNYYLNNLENDAYEA"
     gene            complement(18561..20582)
                     /locus_tag="LP493_003041"
     CDS             complement(18561..20582)
                     /locus_tag="LP493_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015535387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1738 domain-containing protein"
                     /protein_id="HBL2135105.1"
                     /translation="MTEQNKTTTIPLPVPGKDMDSIMQSLESGVEELFTSNRYQEFLK
                     TMAKFHNYSFNNTMLIAMQRPDATLVTSYKNWQSMGRQVMKGEKGITIIAPAPYKKMK
                     EKEVLDENQRPIMGSDGKPKTEQVEVTVPHFKAVTVFDIAQTSGEPIQTLAPELLTAA
                     VQDFDSFMQAIQKISPVPIRFDEIDDNANGYYHNADKEIVIKKGLSESQTLKTAIHET
                     VHAKLHDREIMESLGVEKDRLTKEVEAESVAYCVCSSFGLDTSDYSFPYIAGWSSSRE
                     MKEMKASMDVIRKTAGEMIDQLTEELEIILEEKQKTELHDKYGILVDALEAAGYRYDY
                     RESEPGHIVLAPDGTHEIAGYLQFESWGDIKDWLEDTIAEGTDISERVDRALYPFKFD
                     YTLEEEMFRGNGDRYAIYHVDEDTPGKQHLFMNMAMVKEDGITIDAANYKCVYSGRLH
                     ENEKLDDLYAVFNDNPPADYKAHSMSVSDVIITNRGGDMQAYYVDRFGFAELPDFAVQ
                     REKILDIVPEIENVDYENDLTCISFYAAECAEFPVMGEVHYDLTLPEALEAYEKIPSE
                     RMHGLKCVGFDLKDGSDYEGMQSLMIEGKIQKEFLNSIPGFRENSYVQNAISRVEKYL
                     EERHPNVENPLESNKKVDNEKNISKEKNEKELNIQMKPIPKKKRGEMSL"
     gene            complement(20665..21714)
                     /locus_tag="LP493_003042"
     CDS             complement(20665..21714)
                     /locus_tag="LP493_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005334802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2135106.1"
                     /translation="MNFNEFVSEVKDNIKLFLPEEYENVEVSTMECQQLNRAYTGLMV
                     RKEGEMLTPTINLNQLYEAYKAQPGVTMETVCRKIADIVIEAPIQVDLKAIFNYEDVK
                     DKLFIRVSSAEANKEVLENAPHQLKEDLAITYHVAVDKDENGLSSMFIKNDLLEQYGI
                     SAEQLHEDAMKSSPRVMVPEVSSIGALIDEMYQKNILMLTPDEREMLQETLQESSEMP
                     TFFVVTNTERVDGAGVIFYPEFMDNMGELLGNDFFILPSSIHEMLILPDDGQVDAEML
                     RDMVKEVNATQVAPAERLTNDVYHFDTKDHVFEKADRFTERQKEKEAQAAKTEKAGKE
                     QPDQKPKTKKHDMEL"
     gene            complement(21743..23854)
                     /locus_tag="LP493_003043"
     CDS             complement(21743..23854)
                     /locus_tag="LP493_003043"
                     /inference="COORDINATES: protein motif:HMM:TIGR01056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HBL2135107.1"
                     /translation="MYLVIAEKPSVSRAIAEVIGAQEREDGYLQGTDCMVSWCFGHLA
                     EYVSPDAYDEKFNQWRYEDLPIIPKDWKVTVSEDKKDQFYILKRLLNSPEIEYVVNAC
                     DAGREGELIFKHVYDLSGSKKPVKRLWISSLEDSAILDGMQHLRSAEEYRHLAEAAVC
                     RSQADWLVGMNATRAYTTKYFKKLTVGRVQTPTLAMLVERAGQISNFQKEKYFNVELD
                     CDGIPAVKPKIFDPDEAEQLRSRCQGSEAIVTAVKETEKKVKAPKLYDLTTLQREANR
                     IYGMTAKQTLDTAQNLYEKKLITYPRTDSQYLTEDMEQTARNVVRQIYEKYQLTGPFD
                     QPEQPDVKKVMNNSKVTDHHAIIPTMELSSCHLDELKSWEEKILFLIAVHTVMAMSKE
                     HVYQETEIEVECQGEIFKAKGKTVLQDGWKLFENCFKNKDRMAIVDPDQEMKEKIPKV
                     TQGQTFYAVAAEKTEHFTSPPKPYSEDTLLAAMETAGNKEFDEDTEKKGLGTPATRAG
                     IIEKLIYSQYATRKGKQILPTEDGKVLVEILPDFLKSASMTAEWENQLLLMEHGEIAP
                     EQFMTGIKNMLTMMLNGCDAISEEETRRFQTRESIGTCPVCGSLVYESKPNFYCSNHD
                     CHFALWKDNRYLQSMEKTMDKKMAAELLKNGSVHVKDLYSRKKNMYFEADLHMDTDET
                     GKVNFSLSFPKKKSKNKSKKK"
     gene            complement(23927..>24403)
                     /locus_tag="LP493_003044"
     CDS             complement(23927..>24403)
                     /locus_tag="LP493_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003864570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HBL2135108.1"
                     /translation="DDITDDSTKEFLTVTTKNNNTFYIVIDRSATSQNVYMLSQIDEN
                     DLSEFLDKDSTAAVVTPQPDTSKVVLDETNNEDVDKEATVDPEKTSSAKTNMGAMATI
                     LILALGGVAAYYYFKIYKPKKEEDEDDQPEGLETGGLEEVPDEEESEDEDFEENEK"
BASE COUNT         6969 a         5145 c         4384 g         7905 t
ORIGIN      
        1 tttaggacat agcagtttag aaactacaat gtctacttat cttcatattg ttcgagagct
       61 tgaagatcag gataaagaaa aaatcaatac tgtgttcgat agtttatata aaaatgataa
      121 ctagtttggc acatttttgg cacaaataca aaacaaaccc ctgtaccgca aaggatacag
      181 gggttattta tacgttcctg actggaattg aaccagcgac ctatcgctta ggagagctcc
      241 aacctattgt cactctctgt caatctgagg taaggtaaac ccatatggga cactatataa
      301 aactgtttcc gattcaattc gagttattct gaataccccc tctgtcaagc tctgtaaagc
      361 tctgaaagtt agctgattgt ttgccccagc taataatcgg ggaatgcctt gatattacca
      421 tcgacatctg ttatatgacc accatgcttc gtacgttcga tcatggtaaa cagtattcaa
      481 ttaaactttc ctatcataag tacaagatat tttcttgtct ataaataata taacgcatac
      541 gagacggttt gtccatgcgt ttttgactgg caaatttata agctgctttc atatttttaa
      601 acacggacat aaccagtaga tataccttcg attcggttgg atgctcccgt actctgaatc
      661 aatgcaactt ctaagagtgt tttcaattca tctacattgg cttcgagaaa taattcctgt
      721 ttgcctttat gttcatggat gctgctaacc atctgaacaa tttcaggtgt taacaacttc
      781 gcaggactta caataaaatc aaagtctctc ataggaatct ccttcatttc agatttatct
      841 ccgtcattct atcatcaaat gatggagata gaatatccat atacacaata aatatcctca
      901 tttcatccat atattatatc gttttatgaa tcgttttttc actaaaatta cactattttt
      961 tcactatttt tcattacttc atcgtcttcg ccagtgaatt gagcaatgcc cgcatctctg
     1021 gattcgccaa tacttttgcc agaagttccg gatcgacttc atcagcaaca gtagtattat
     1081 tattttcctg ctgtacatgc atctgtggat ccagattctt tttctcataa aatgcttctt
     1141 caaaaagctc tgcatttttc cttctgtcat catccagaat atgagagtac acatctgtaa
     1201 ccatattgac ctgagcatgg ccagaatcac cctgtaccgc cttgatgtct ccaccattca
     1261 gtttcagctt ataagtaaca ctgctatgac gaaaactgtg aaatacaacc ggtgggagat
     1321 tatagtcctc gatcaatttc tttaaagggc cacggattgc tccatcacca agaggaagac
     1381 caaaggtact tgccataacc aggttatagt ccatatattc gtcacccagg atttctttca
     1441 tttcatcctg ctcagctttc cagtctacaa gcatattagc aacgctcttc ggtaagaata
     1501 tcttacgtac actactttct gtcttcggtg ttttcagaat acggaccgta gaattcttct
     1561 tatgatttgt cggaaatacc aacaacacat cttttccatc caatgcattt aaagattctt
     1621 ttcttatacg ctgtgattct ttgttgatga agacatatgc acggttttct tcaattgcct
     1681 catgagaaat atctacacaa tcccaggtaa gaccaagcag ctcaccaagt cgcagggaac
     1741 atgagaaaga tagattaatt gcgagcttta atcgttcatc ttcacagaca ctgagcgcat
     1801 acatcaatgt atccgctgtc cagatgtctc ttttttgtga tttatgtttt ggtacagtcg
     1861 catgggtgca aggattcttc tccatcaact cccatttcac tgcctgttca aaacagtttc
     1921 taagcagctt attaatatcc ctgaccgtac tggaagatac aaattcattt cgactggttt
     1981 tattcaatgg attgataact gcacgtctct tcaaaagact ctgataatat ctttcgatga
     2041 aacgggtatt gatctctgag agtttcgtat caccaatgat cggaagaata tagttattga
     2101 taagagagac atttccttca tatgtagaaa gcgcccagtt ttctttgcca taaagtgcaa
     2161 catattctgt aataagctcg tccagtgttt tgcatttacg gacgacaaat gatcccatct
     2221 cttttttata ttcaatttct ttttttcttc tctttgcttc ggctttcgtt tcataggttt
     2281 cccacttctg tttcctctca cctttttcat tcgtataaga atagattaca ttaaattttc
     2341 cgtttcgttc tcttatagat gccatattat tgcatactcc tttccaaatc tctttgctcc
     2401 atccagtcct caaattcatc ccgacggatc ctaactcgac tgccaacttt tattactgtg
     2461 aactttcctt tatccgccca cttgttgatc atgcttctgc tgacctttgc cagataggaa
     2521 gcttcatcaa aagtaagata ctttatattt ccattgcttc ctcgtattcc ggtctgtgat
     2581 aatttcttcc gccggaaatt agccagggca atattttgtt cctgtgcaag ttcttcataa
     2641 tcattcgatg gatccagctt ataccgatcc tgaccttcca ggaattttcg aaaactctct
     2701 tttgtgatcc ttttcttttc tgcaatcaca atgaattcaa aaaaatgact atactttgga
     2761 ttatcaagaa ttgtatatac tgcgcttctg gttgttccaa gcagctgtgc catctcaggc
     2821 atcgtaattg ttgcatcttc cagaagagcg tctttttttc tgtcttcctt tgttcgatac
     2881 cgggactggc ttttatacca gttctgaaaa gattcttttg gtattcgttt ccagtaatcg
     2941 acaataacag cttccatttg atttttcttg agtaaatcat aaacaagata ctcatcaaca
     3001 cccaacagat ccgcaacttc cttaacggaa taggaccagg atttcaattc tttccctggt
     3061 tcttctccgg taactttatg gtatttaatc tgattggcgt accatttttc aaagctggca
     3121 atattgattc gtatctttcc agcaatctct ttagattcaa aaacattttt atgcaccagc
     3181 cagtatcgat ctgtcttttt taatcccagc agctttccca tttccggcac ggtcatccag
     3241 gttctctttt gtgtcggacg ccgtttgtaa ggactgtctt ctgatatctt tgaaatgatc
     3301 tcttcaacat cgtccatttc cggaacttct ttttgtttca taattgctgt tgccatttat
     3361 tcttcacttc ctgtcttttt tagtgttagt tttttttctt atatcatatc tcaaatccag
     3421 ataaaaattt aggatgtcga ttgcagacaa aatctgcctg atcaacaccc tgttttttat
     3481 tgttccaagt tatcgagcca gtcatcgaaa ctcttcttag agatgcgata ctttccgcca
     3541 tccaactgga tccaccggaa ttcctttttc tttaaaaggt tataaatagt aggtctgctg
     3601 actcctaaga tttcctgtaa ctcttgaact gtataacatc ttttttctga catttcttta
     3661 tcctcttttc tttgaaatat gaaagaaaaa ttatcccttc atataacgaa acgctcagag
     3721 catgttttac agtggtcaaa agcaaatttt tttacttttt ttcttgcgag tttttttaat
     3781 gcaactcgta agaaactcgt aacattagat ttttacattt ttcatgaaat taagtaaaga
     3841 aaaagagcat atggaattga atccatacac tctatgatta ctgaaacttt atttcatttt
     3901 taattcaaca aacttgaatt tatatatgtc tttgcaaata taccatatct attagctgta
     3961 caccgccctc ataaattgtg tggtcataat tgtcagtaaa aaaattggga atcttgtgag
     4021 aacgaacaaa tccacatttt tcataaaatg gtatcgtcaa tggactgtca cctgttccaa
     4081 cttgcaaaac agaatattca tctgcatatt tactggcaag aaaatcaatt agtgctttgc
     4141 catagccctt tccctggttt tccggatcga ctgcgatatt cttgatttca agtattccgt
     4201 taccttcatc ggtgacaaca cattcagctt ttacatcatt atcttcaagc acatacatag
     4261 ttcctttttc aagataacga tcaaccatgc tctcctgttc atcagctaat aacaataatg
     4321 atataaactg ctttttattt ttgttaactt ctcgaatttt catacaactt gttactccat
     4381 caattgccat ctaatttaat tcatcaaact tgaagttgta ggtttctttg ctattatatc
     4441 tttaaaattc gttttgcttt cgcattaaca aattggataa tcgggcctga aatgataact
     4501 gtaatgattg tgcatatgcc aaacttcccg ccaagcaaaa cacctattat cacaaccaga
     4561 atatctaatg ctattcgaac aattttaact tgccagttgt tcttttctgc caaggcaaaa
     4621 gtaactgctt cataagagcc acgaccaagt gaggcagacg catatagtcc ggtcccgaca
     4681 gcaaacaaaa taacacccag caacatgata aagaagttga accatcgata tgtactgtag
     4741 acatggcagg tggcaaatac atctacacag gtgctgtata caatttgata tagcaccgtc
     4801 ccaatatgga tttgactttt atcgtaaatt aatgcaaaca aaatcatccc cactgctaca
     4861 acaaaagatg ccataccgat gctcaagtga aacgtttcag cgataccctg ccatagcact
     4921 gcgagcgtgg cgccaccaaa tcctgcatac agtgcaagtg taatgccata ggctgcaaca
     4981 atggaaccta tcacaataat tatcaatttc tttaataagt cccgcaatag caaggattcc
     5041 cttttgtgct tatcaaacat cataattcct ctattctaca aattccgatt ttaatgtctc
     5101 tattatacca taatgatact attataaaaa aggaaaaaga gctccttcga gctcttttga
     5161 ttcagttctg taaacttgaa tttgacttgc ctattttctt aaaatctcat gtggagcttc
     5221 tatttcattt gccaaggtat gctctgttaa ttctgacatc aatttcaatt ttttattaat
     5281 caatggtcgc atacaattag gaacatgttc ctgatgcgct ctgtggattg ctacacattc
     5341 cttacagttt ccgtgataac gacaggcttt caggcaagga cagtgatctt tgtctttata
     5401 ctccttacga aattccgctg caaattcttc ttgcagtctc agtccctcga cacggtttcc
     5461 cttatgaaat tctaccattg catccagttc tttctggttc ccttcaatct tcatgttatt
     5521 atagcgcctc catttcaact attcttcatt ttctgataaa ttccgatttc tattttcgtt
     5581 tccatagcat agtgtactct ttttcaccag tagtttcatc caagccttca tattgaataa
     5641 tgaacccttc tctttggtaa aaagaaattg ctctggcatt cttctggtat acatttaatc
     5701 gtaagctaac ttttttatcc ttaacataat ctaataaaag cttacctatg ccacatgact
     5761 gcatttcatc ggagacaaaa ataccttcta tatatttatc atttagtcct acaaatcctt
     5821 gtatcatttt atctgcttca aacacataaa cttcgtattg tgacatcatt tcttttacta
     5881 attcataatt acttttccag tattgattgg aaataaaata atgggctttc agatttgtct
     5941 ttaaccatat gtcagcaatt ctatcgatat ctccgttcag caactttcta atcataacaa
     6001 atattctcca caactacatc ctttatgctt ttctcttttt tccattctat cacaagctca
     6061 ccattaatca tcaatttttt gatatttttt ctttttcccc actgtaaaac agcctctgag
     6121 cgtttcgtta tatagaggga tacaaataag agcaagatcc acccaggtat taccgtatcg
     6181 ccattttatg gctacggcat acctccgggt aagtctcttg atggggattc cgattcccca
     6241 taccctcgta cagacatcaa agatatctgt tggctctcta tcaaagatag tcgcagcact
     6301 ttatataacc ggaagggaca gccggttaaa aagtgtaatc gcacatccaa gatgtcttat
     6361 caaaaaagaa ggaggactat ggcaccaaag aagaaagaaa agaatctcaa aaggagtaac
     6421 atcatcacat taaaattaac ggatattgaa ttggcagtat taaatgaagc cgctgacgtt
     6481 acaggacttt ctcgttctga atatgtgaga aaactactac ttgaaaagca aatcaatcat
     6541 cagattgaag tggttgcaga catgaatgat ctcagaaaac tggtcagtga atatggaaaa
     6601 attggatcga atctcaatca gattgccaag cattttaaca gcggtggcag tcagtcacgt
     6661 gctatagaaa atgaaatcca tcagtgcatc acggacttat tcctattgag aaaagaggta
     6721 ctgaaactgg caggtggtat gaatggcaat cgtaaaacac attaaaagca gaaatgcaaa
     6781 ttactcagct gctatcaatt accttctgtt tgaacatgat gaaaaaaccg ggaaaaagat
     6841 tgtagacgaa tccggacgaa gcatcatgcg aaaagagttt tatatggatg ggctgaactg
     6901 tgatccgatg tcttttgaca aggaatgtga actgacaaat gctcattttc acaaaaataa
     6961 gaaacgtgca gatatcaaaa gtcaccacta cattatcagc tacgatccag ccgatgttac
     7021 agaaaatgga cttaccggac caatagcaca agcaatcagt ttggaacttg caaagcagat
     7081 gtttcctgga tatcaggcac tggtggttac tcatactgac ggtcacaatg agtccggaaa
     7141 tatccatacc cacatcgtca taaacagtgt gaggaagact gcagtggaaa ggcagccgta
     7201 tatggataag ccacatgagg aagctgccgg ttacaagcat cgttccaccg ataaattcat
     7261 gaacgcattc aagaaaacag tcatggaacg gtgtcaacaa gaaggatttc accagataga
     7321 tcttcttgtt ccagctgaaa gaaaaactac tcaaaaagaa tatatagcac agaaacatgg
     7381 tcagcaaaaa ctggatgaaa tcaatcagaa aattatcgaa gatggtctca aaccaacatc
     7441 cactgtattc cttacgcaga aagaatattt gcgaaatgcg attgatgaat gtgcttccac
     7501 atccaatagt tttgatgaat tccaatccaa acttctggaa caatttcaaa tctctgtaat
     7561 tgagcatcgt ggcagataca gctatcttca tcctgatcga cagaagcgga ttactgaacg
     7621 ttcactggga acacgatatg gaaaagaaca cctgaaacag accttcttac gcaaggatcc
     7681 attggccatt ctctacgtca gatctcacct gcgcctggtt gtaaatctcc agacaaatgt
     7741 gaaagcaatg cagagcccgg cttatgctca tcgggtaaaa ctttctaacc tgcagcaaat
     7801 ggcaaatacc attatctacg tgcaggaaca tggatttgat acgcagtcag atttgaaaaa
     7861 tacactggtt gcatcaaagc aggaattgaa agaaatgcag acacagtttg ctcagcatcg
     7921 ttccgatcta aggatcctca acgatcagat tcgttatacc ggtcagtact atgcaaacaa
     7981 ggaagtttat tcccagtttt caaaagcaaa gtacaaagga aagtaccgaa aagaacatgc
     8041 gaaggaaatt cagaaatatg aagaagccag aaattggctg aaatcctttt atcaggatgg
     8101 aaatatgaca agcctaaaaa ccttgacttt gcaaaaagaa aaactgcaac agcagatagc
     8161 ttccgaagaa gaagcaataa gcagcttgaa agaaaaatta aaagatctgg atactgccga
     8221 tcagaatgtt gatgccattc ttcagatgca gataccagaa ccagtaagat caaaaaacaa
     8281 agatctcgaa cgataactat cacaaaacaa aggaggaact atcacatgac acaagaagaa
     8341 tttaatattg tatttgaact tcagatgaga aagtgtgccg atattctggc acataaaaag
     8401 aaagaatata ccggtgacaa tattgaccgc ctcagtgcat tcaagattgc tgccgcctta
     8461 caaaactgcg atccaaaagc agcactggcc ggtatgatgt cgaaacatgt cgtatccctt
     8521 tacgatatgt gttattccac tctgttacat tttgacatgg aacagtggga tgaaaaaatc
     8581 acagactgca tcaattatct gatcctttta aaagctctgg taaaggagga acaggcctat
     8641 ggatcacatt gaaacagcta tcttaaactg ctatggaatc cgggaagcag aacagaatat
     8701 ggtctttgct gccagactca cacaacacgg tcatacgatc cagaacatgg cagatctgat
     8761 ggatctttac cgtcaatcct acagtcagaa gactgtagaa aacattgcag ggcttccgca
     8821 tccaaccgtg cagaaattca tggtcattac cgtagctgtt gttggtgcaa gcagacgctt
     8881 cctggcacag atcacaagac atcagaatga agtaaagtac atgagtgcat ctctgcagta
     8941 cagcaattat tccggtcatg ctgcatttgc tattccatat ggaatcatga aagcagataa
     9001 agaaatccag gatatttaca agaaaagctg tcagtcagat ctggatcatt atgcagagct
     9061 ttgtgcctta ggcattgatc atgattcagc cggatatgcc acacctcagg gacttcgaaa
     9121 cgtactgatc atcagcgcga caccttacca gtggaagcat atgattggtc agagaacctg
     9181 cagaaggaat acggatgaaa ccaggattgt gatgctctat atctggcaaa gattgtacaa
     9241 attaagcccg attctttttg caccagatct gaccggtcca ttctgtcaga gaggaagctg
     9301 catggaaaaa cagatgtcct gtcagaatcc catttcaaaa ctttggatgc ctgcagatat
     9361 cttaaaaaca gattatccat tgctgatccg gaaggagatg agcagccata aagattaaac
     9421 tgattgactt tggtctgaaa gcagatcatc atccattccg gccacatgaa aatgatgccg
     9481 gtgctgatgt attcatgcct tatgattgcg tattaaaacc aggcgaggtt gcaagaattc
     9541 cgcttggatt cggtctcatc atcccagatg gatttgccgg atatgtcttt ccacgaagca
     9601 gcatggcagc aaaaggactg gtatgtgaac ttccaccgat tgactccggt tatcgtggtg
     9661 aaatccatgc cattataagc aacgtgagca catcttctca gaccattcat aaagacacac
     9721 gcgtcggtca gctggtgatt acaccggtcg tgatcgcaga ttttgtcctg gaccttggtg
     9781 aagaacgagg aactggggca ttcggaagca caggagaata atactatgat tacatttgga
     9841 agaaaattaa aacacttaag acaaaaaaat catctcaccc aaaaagaact tggcatggct
     9901 gttggatttc ccgacagctg tgctgatgtc cggattgctc agtatgagag tgatgtccga
     9961 acaccgaaag aggatcttat gaagctcttc gcatcaacac tcggtgttcc ggttgaactc
    10021 tttaccgtac cggtactctc agaacccagg gagtatgagg cggcggagta ttggaggtat
    10081 gagttagggg cggaactaga ttaagtgtcg tatactgtaa tgaggcaacg gattatccgc
    10141 tgcctctctt ttatcatttt aggggtaata attgaaaata acctgtattg agcaatcctc
    10201 tttttctgcg ctttatctac atatctatat atttcacttt atttctgttc catcgataag
    10261 aagcacatat ttatccggat tatgaacaag atcataatct tttccatatt caatcggtct
    10321 aaattctatt tgcataatgg attcgccatt ttcgatatct tctttccaag aatatacggt
    10381 catatcaagg ctggttgcat atccatgatc tgtagaaaat tttattgaat gaaatgaatt
    10441 ctctttgtac atttttaaaa gcagtcttgc aaatgcttct ttatcagaaa tattttttct
    10501 gttagcaact actgtaaaat tttcatctct attcatagaa aaactgccaa ctacatctgg
    10561 ctcaccttct ttatacttta ataagctttt tccaattatc attccaacaa taatcgaaaa
    10621 aacgatagca acaaatacaa gtgttatatt atttttcttc attttattaa gttccttaga
    10681 attatatagt tgaattaaat ctgtatttca aataaaacgc ctacaaagtg ggcgttttat
    10741 tatcttaata ctatttaatt tttttcattt cttcaacaaa ctgttcttgt gtaattctcg
    10801 catttaatac attttttcct aaaaacaatt catctttatc acatgtagca aaacatgatt
    10861 ttacccaatt aactttttta tttaatttta aataatgtat gaaaccagat aaggagaaaa
    10921 cgtaaattgt gttaatgata gcagacatga gtatggagtg aatatcttat ttggaggaaa
    10981 aacaaatggt acaatcaatc tttgaggaaa tgggcggcag atacgaacgg caaggcgaat
    11041 acattttacc ctgccttacc ataccacccg aaaaggaaca gtcgatagac ttattcggac
    11101 ggcggcactt ggactatctg cgggagtacc gcaaaattac atacaccaat cttctcacaa
    11161 gcggcaggct caatgcttac cttgccgaca ttgacagaca ggcacaggaa cactttgaac
    11221 ggctcataga gggcatgaag caagcacagg gcataacgga atgcctaaag gaagaaaacg
    11281 ccttagaatg gactggaaga acgaataaca taagggcttg tgcgagggag attgtggaaa
    11341 aggaaattat ttttgcataa acagatgatt agtggcaggg ggaaatcctg ccgctttttc
    11401 tgctttagtt tgtcagcttg acaaataaag ggttaaggaa tataattaga ttcagtatta
    11461 tacaaggagt taataaatat gcggcaaggt attcttaaat aaactgtcaa tttgatagtg
    11521 ggaacaaaaa gtagcagtcc cgtttcactt ttaatatggg gcttagtttt ttgtacccag
    11581 tttaagaata cttttatcat gtaattttat atgcccgaaa acatataagt gttttggggc
    11641 tattggagtt atttacccag tgataggagt atttatcact gggtattttt atgccctttt
    11701 ttgggtgttg ataggaggaa aatcacatga aaataattaa cttaggcatt ctggctcacg
    11761 ttgacgcagg aaagacaaca ttaacggaga gtttattgta taccagtggt gcaattgcag
    11821 aaccagggag cgtagataaa ggcacaacaa ggacagatac aatgaatttg gagcgtcaaa
    11881 ggggaatcac tatccagaca gcagtgacat cttttcagtg ggaggatgta aaagtcaaca
    11941 ttatagatac gccaggccat atggattttt tggcggaagt ataccgttct ttatccgtat
    12001 tagacggagc agtattatta gtttctgcaa aggatggcat acaggcacag acccgtatac
    12061 tgtttcatgc actacagaca atgaagattc cgacaatttt tttcatcaat aaaattgacc
    12121 aagaggggat tgatttgcca atggtatatc aagaaatgaa agcaaagctt tcttcggaaa
    12181 ttatagtgaa gcaaaaggtt gggcagcatc ctcatataaa tgtaacggac aatgacgata
    12241 tggaccagtg ggatgcggta attatgggaa acgatgaact attagagaaa tatatgtcag
    12301 ggaaaccgtt taaaatgtca gaactggaac aggaagaaaa caggagattc caaaacggaa
    12361 cgttatttcc cgtttatcac ggaagcgcta aaaacaatct ggggattcgg cagcttatag
    12421 aagtgattgc cagtaagttt tattcatcaa cgcctgaagg tcaatctgaa ctatgcgggc
    12481 aggtttttaa gattgaatat tcagagaaaa ggcggcgttt tgtttatgtg cgtatatata
    12541 gcggaacatt gcatttgagg gatgttatta aaatatctga aaaagagaaa ataaaaatca
    12601 cagagatgtg tgttccgaca aacggtgaat tatgttcatc cgatacagcc tgctctggtg
    12661 atattgtaat tttaccaaat gatgttttgc agctaaacag tattttgggg aacgaaatgc
    12721 tgttgccgca gagaacattt attgaaaatc ctctccctat gctccaaaca acgattgcag
    12781 caaagaaatc tgaacagcgg gaaatattgc ttggggcact tacagaaatt tcagatggcg
    12841 accctctttt aaaatattat gtggatacta caacacatga gattatactt tcttttttgg
    12901 ggaaagtgca gatggaagtc atttgtgcca tccttgagga aaaatatcat gtggaggcag
    12961 aaataaaaga gcctactgtt atatatatgg aaagaccgct tagaaaagca gaatatacca
    13021 tccacataga agtcccgcca aatcctttct gggcttctgt cgggttgtcc atagagccgc
    13081 tccctattgg aagtggagtg cagtatgaaa gcagagtttc acttggatat ttaaaccaat
    13141 cgttccaaaa tgcggttatg gagggggttc tttatggctg cgagcagggg ctgtatggat
    13201 ggaaagtgac agactgtaaa atctgttttg aatatggatt gtattatagt cctgtaagta
    13261 cccccgcaga ctttcggctg ctttccccta tcgtattgga gcaggcttta aaaaaagcag
    13321 ggacagaact attagagcca tatctccact ttgaaattta tgcaccgcag gaatatctct
    13381 cacgggcgta tcatgatgct ccaaggtatt gtgcagatat tgtaagtact cagataaaga
    13441 atgacgaggt cattctgaaa ggagaaatcc ctgctagatg tattcaagaa tacaggaacg
    13501 atttaactta tttcacaaat gggcagggag tctgcttgac agagttaaaa ggataccagc
    13561 cagctactgg taaacttatt tgccaacccc gccgcccgaa tagccgtata gataaggttc
    13621 ggcatatgtt ccacaagtta gcctaacagc ttgcataagt cgtataaaat gagatttgaa
    13681 aggattagaa gctaattatg atgaaatgcg aatggatatt atgtcctgtt tgtgggagca
    13741 aaacccgtaa taaaattagg aaggacactg ttttgaagaa ttatcccctt tattgtccaa
    13801 aatgcagaca agaaagattg attaaagttg acaacttgaa gataactgtc atcaaagagc
    13861 cagacgctta agacgcagag ccgatgaaat tgtggaacaa ttcacgaatc atcggctctt
    13921 tttgtttcgt atttgaaaga acaaactcac caaataaaaa aaacgatatt cgggtgggtt
    13981 attttgttat accctaaatt accctctgaa tttgttttta aatttggagg gtttttatgt
    14041 tccttttttc gggcggttgc ccatctgctt atataaagca aagtttattt atacatagca
    14101 catcagggaa tggcgggaag ccagttaaaa aaatccctgc cagtgcaacg gtacttccca
    14161 ccatgaaggt agaagtacaa tctccataca acagaattag tatttcccat aaccgtaagc
    14221 agtagctaaa tgtattgaca gttcacattc atagccggaa tatcccgctt gcggagcata
    14281 gctttttttg accgcaaagc attaggcggg ttacagtaaa taaaaatgga cacggcgata
    14341 cctccccgat accgccgtat ccttaaaaaa gggcgacttt aatacactac ccgcaatcca
    14401 ttctataata gggaacagcg gcttttgcgc aatattaaat aaaaaagccg ataacacata
    14461 ggttttttga cctaatgcgt tatcggctct gcgtctatgc gtctggcact tttaatcatt
    14521 tttttttgaa tttattatat gtgttagcta actgtccaca agccgcgtta atctctctgc
    14581 catgagaaac tctcatagta acttcaagtc ctgcttgctc taattgatgt ttgaatgcaa
    14641 ctatttcccg tttctgtggt gctttaattc ttgaattgct tgttgggttg tattgtaaca
    14701 cgttaatcat aacttttttg ccccgaaacc attttgcaag ttgtcttaca tctgagggcc
    14761 ggtcatttat acccggtaaa agcaaatacg caaagacaat tttgcgatta tgcctttcag
    14821 aataggataa ggcttgctta acaacatctt caatagcata tatgcgcatg tgaggaataa
    14881 tacgatttct tgcagattgt gttgctgcgt gtaaagatat tgtcaactga attttaagat
    14941 gttcctcgcg caattttttt aattgatcga ccggaccaac tgttgatatg gtaatgccgt
    15001 cggttggaaa gttgagccca tatctatctc ggagaatatg gattgctttt atcaagttgt
    15061 cataattgaa taaaggctct cccataccca taaaaacgat acggtttact tttcgacgca
    15121 acaatataat ctgttgtacg atttctgacg atgttagatt acgaacaaag ccatttcgcc
    15181 cggactcaca aaaaatacaa ccaacaggac aaccgacttg tgtgctcacg caaacagttc
    15241 caccatctcg ccgcttgata aaaaccgttt caatgtattt gttgtctttc agttcgtaaa
    15301 catacttttc agtatcactg cttttgcaaa tattttttac caacattgat agattttttt
    15361 tgcgtggtaa ttgcttatat aattcttcat ataaggcttt tgcttcattc tcgccaataa
    15421 cttccgacat ttctttgtaa gtaaatccgt atggatcatt ccgtacttcc gcaggcgtat
    15481 atttaggtaa acgtttcatt tttatatcct ttcttctaaa taataaaagt ttgtttttct
    15541 gtatttttga ttacaatctc taatttttct acatcaatga tatgcgtcaa tttgcattta
    15601 gggcagaaaa gaggaaaatc ttttaataca gtattatgaa atacttgaac tctcgtcttt
    15661 ccgttacaaa tcggacattt tatccaatat tttttaagca ttatatttca ctcgtccttt
    15721 ttacacaaaa aaatgcaggt caatcctcaa catgagcatt gacctgcatt tataatgcac
    15781 agagcagtac aacaaaacta aggcatagct tgcactatgt ctatactata tctatacgtc
    15841 gttagttttt tgtatagcat ccgcaaaata agcatgacaa aaaagcccat gttgaaaatg
    15901 ggaaaatcct ttttttcaat gcttatctaa tacgcatgct atgcaacata aacgccgcct
    15961 ccttttacat aaattttatt ttatcagaaa atcagtctac tgtcaataca caacaggaag
    16021 tatttaacct aatgatatga attgtgtgga catatccaaa aagaaaggtg aactgtaaaa
    16081 tgtaacaggg tgaatgaaaa tggcaaaaag acccgtacca ttgtacgact ttaaggcttt
    16141 cggggcagct ataaaagccg cgagaaatga atacggcgag agccgcaaaa aggtaagcga
    16201 cgagttatat atttccccgc gctaccttgc gaatatcgag aacaagggac aacagccgag
    16261 tttacaggta ttctatgacc ttgtaacccg gtatcatatt tcggtagatc aatttttctt
    16321 cccgaacagc aatgcggaga aatccaccgg gcggcggcag cttgacgcgc tgctggacgg
    16381 tatgagcgat aaaggcatac ggattgtaac cgcaacagca agggagataa cggaagtcga
    16441 aaaagcagag gattaacctc acaatatgag aaatcgggag attgcagcgc atggcggctg
    16501 caatcttttt ttgcgtccaa aatcaaagga acgcgcaaca aatgtagtat accattcatc
    16561 cgtgttatct gcagaatatt ttgcgttatt taatattgaa tttcctgttt tatttatagt
    16621 tataatttct tgatctttgc cgttgatcat ttgcttgatt ctcccctgca tgaatttctc
    16681 atttgtcttg attagattct aattctttta atttcttttt catttcttca tattcatcga
    16741 aataagaaat taatgctctt tcaacagcaa ccgtttttgt atgtcctgca tctttacaaa
    16801 aattttctaa tcgctcataa ataggagttt caatacatac attaaggtat gttccattct
    16861 tttttggtct tgccattttt ttctccctgc atttaatact attacatgaa ttttcctcaa
    16921 ataattgtac cactgaaaac tacttaaatc aactattcac tacttgttat caaatatata
    16981 aaagataaaa tcaggttttg tactactaaa tgattttaaa caaaataagg cccaaaaggg
    17041 aactttccct tttgagccta tacactttat cagctaacat attttgcttt catttttcct
    17101 catggtcatg aggctttttt ctcttaaatc gcattctatg aatcctttga ttgttccttc
    17161 tgttcttcaa taattcgttc tgttgcttta tgaattctgt ccttagaata gggtggtctt
    17221 aaattcaatg acaaccggcc ctttttgatt atatacgttt cactgccatc ctccgaagat
    17281 cctttcaacc agcaatcatc cggatacttc tcagcgaatg cccgtaaccg tttctgcaag
    17341 ctctgattga aggtatacac atcatagaat ccgtcatctt cattggtcag aataatcgtt
    17401 tctttttcac actttaacct tcgcatattc tacccccgct ttctttccat ttcctgatcc
    17461 aggtatttgg gtatcggttt tccggaccgg cgagcaatgg caatctgttt ctgatgcaga
    17521 cgtttgatca cggatcttcg tttcttagat tttccatcct gttgatttcg ggaggtctga
    17581 ttgttgctgc tagcatcaga ggtcttttcc tgattcttct tctgattatt caccagaccg
    17641 tccaccatat cataattggc ttcggtacca gattctctgc ttcgttcata agtgccgttc
    17701 tggtagaatt tctggtaatg ttccagacgg attttaccat cttgttttag ctgttcgacc
    17761 ggatttagcg gtacttgctg ttggatgtaa tcatgaatct tttgttttgt cttttcatcg
    17821 aatttcttac attcttcgac aaccattttt ccataggcat ccaggataac accctgggcc
    17881 tgatctcggt atacctgatg ttccatcaaa taaaactgtt ttccatcaat aatgatggtg
    17941 tctgtggcaa tccagtttcc ttttttccca tcgatctgat aattctcagt ttccatagtg
    18001 atcagtgcac cggatgtatt gatacgaatg aatccggcca gatactgtgg atagttttca
    18061 tctacatagt agcaactgat ttctccgttc ttgttcaata cgagcacgtc actgacttcg
    18121 cattgctttt tcattcgttt ccagatgtca gcgacttttt cattttcctg catttcatga
    18181 atcgagacta atcggtaatt ttcgacagta atcgacacat tctgctgtct tgcctcttga
    18241 tatggcagat gccacagtgc ttttcctgct gtctgctgat ctactcggta gactgcaaat
    18301 tgattaagct tcataggcat cgttctccaa gttattcaga taataattca gatccagaga
    18361 atagtagtat ttgtcttcga tctgctgtaa ttttccaact gtagaattga tgatctcaat
    18421 catttcatca ttctcaggat cactttcttc ctgttccata acttccaaag cttctttcag
    18481 tgtttggatt gtttcttcct ttgtgtgctg ctggaagata gcagtaatag tcagttcgtt
    18541 ttcttccagg tttacatttc tcataggctc atttcccccc ttttcttttt cggtattggt
    18601 ttcatctgta tattcagctc cttctcgttt ttttctttgc ttatattttt ttcgttatcc
    18661 actttcttat tggattccag aggattttcc acatttggat gtctttcttc caagtacttt
    18721 tccacacgac tgattgcatt ttgcacataa gaattttctc taaatccagg aatcgaattc
    18781 aaaaattctt tctgtatttt tccttcgatc atcagactct gcattccttc ataatcactt
    18841 ccgtctttca gatcaaagcc aacacatttc agtccatgca tacgttctga tgggattttc
    18901 tcataagctt ccaaggcttc cggtaatgtc aggtcataat gtacttcacc catcacagga
    18961 aattcagcac attcagccgc ataaaagctg atacatgtaa gatcattttc ataatccaca
    19021 ttttctattt ccgggacaat atcgagtatt ttttctcttt gtactgcaaa gtctggaagt
    19081 tctgcaaatc caaatcgatc cacgtaatat gcctgcatat ccccaccacg gtttgtaatg
    19141 ataacatcac taaccgacat agaatgtgct ttataatctg ccggtggatt atcgttgaat
    19201 acggcataca aatcatccag cttttcattt tcatgtaatc tgccagaata gacacattta
    19261 taatttgctg catcgattgt aattccatct tctttgacca ttgccatatt cataaataaa
    19321 tgttgttttc caggtgtgtc ttcatccacg tggtaaatcg catagcggtc accattacct
    19381 ctgaacattt cttcctctag ggtataatca aacttaaatg gatacaaagc ccgatcaact
    19441 ctttccgaaa tatccgttcc ttctgcaatc gtatcttcca gccagtcttt gatatctccc
    19501 catgattcaa actgcaagta tccggcaatt tcatgtgtcc catccggcgc cagtacaata
    19561 tgtcccggtt cgctttcccg ataatcatag cggtatccgg ctgcttccag tgcatctacc
    19621 agaatgccgt atttatcatg taattctgtt ttctgttttt cttcaagaat gatttccagc
    19681 tcttctgtaa gctgatcgat catttcaccg gctgtcttgc ggatcacatc catagatgct
    19741 ttcatttctt tcatttcccg gctgctgctc caacctgcaa tgtaagggaa actataatcc
    19801 gatgtatcca aaccaaagga agaacacaca cagtaagcaa cggattcagc ctcaacctct
    19861 tttgtcaatc ggtctttttc tacaccaagg ctttccatga tctccctgtc atgcaatttt
    19921 gcatggactg tttcatgaat agcagtcttt aaggtctggc tttcactgag tccttttttg
    19981 atcacaattt ccttatctgc attatgataa tatccattag cattgtcatc gatctcatcg
    20041 aatcgtatcg gtactgggga tattttctga atagcctgca tgaaagaatc aaaatcctgt
    20101 acagctgcag tcagtaattc tggtgccagt gtctggatcg gttctccgga tgtctgagca
    20161 atatcaaata ccgtaactgc tttaaaatgc ggaactgtaa cttccacctg ttcagtctta
    20221 ggttttccat cgcttcccat gatcggtcgc tgattttcat ccagaacctc tttttccttc
    20281 attttcttat atggtgccgg ggcaatgatt gtaattcctt tttcaccttt catgacctgt
    20341 ctacccatgg actgccagtt tttgtagctg gtaacaagtg tggcatccgg tcgctgcata
    20401 gcgatcagca ttgtattatt aaaagaataa ttgtgaaact ttgccatggt tttaagaaat
    20461 tcctgatagc ggttacttgt aaatagttct tccacaccgg attccagtga ctgcataatg
    20521 ctgtccatat cttttcccgg aaccggcagt ggaatagtag tagttttgtt ttgttctgtc
    20581 ataatactcc tttccaaaaa cgccccacga cattgtgttt atgccgcagg gctttttatt
    20641 agttgacgag atgattattt tttattaaag ttccatatcg tgcttctttg ttttcggttt
    20701 ctgatccggc tgttcttttc ctgctttctc tgtttttgca gcctgcgctt ctttttcttt
    20761 ctgacgttct gtaaatctgt cggctttttc aaagacgtga tcctttgtgt caaagtgata
    20821 tacatcattg gtaaggcgtt ctgctggtgc tacctgagtc gcattgactt cttttaccat
    20881 atctcttaac atttcagcat ccacttgccc gtcatccggt aaaatcagca tttcatgaat
    20941 ggatgatggc aaaataaaga aatcatttcc cagaagttcc cccatgttat ccatgaattc
    21001 cggataaaag atcacaccgg caccatcaac tctttctgta tttgtaacaa caaagaatgt
    21061 cggcatctca cttgattcct gcaatgtttc ctgcagcatt tcacgttcat ccggtgtcag
    21121 catgagaata tttttctgat acatttcatc tatcaatgca cctatacttg atacctccgg
    21181 gaccataact cgtggtgaac ttttcatagc atcttcatga agctgttctg ctgagattcc
    21241 atactgttca agcagatcat tcttgataaa catggaactt aatccattct catccttgtc
    21301 tactgccaca tgataggtaa ttgcgaggtc ttctttcagc tggtgtggag cattttcgag
    21361 gacttcctta tttgcttcgg ctgatgatac acggataaac agcttgtcct tcacatcttc
    21421 ataattaaaa atagctttca gatcaacctg tatcggtgcc tcaataacta tatctgcaat
    21481 ctttctgcat acagtttcca ttgttacgcc aggctgtgct ttatatgctt catacaactg
    21541 attaagattg atcgtcgggg taagcatctc accttctttt ctcaccatca atcccgtata
    21601 ggcacggttc agttgctgac actccatcgt tgatacttct acattctcat actcctctgg
    21661 taaaaagagt ttgatattat cctttacttc acttacaaat tcgttaaaat tcattcttcg
    21721 tttcctcctc taatctgttt ttttatttct ttttgctttt gttttttgat ttctttttgg
    21781 gaaaggataa agaaaaattc acctttccgg tttcatctgt atccatatgg agatctgcct
    21841 caaagtacat atttttcttt ctggaataca ggtctttcac atgcacactt ccgtttttca
    21901 gaagttctgc agccatcttt ttatccatgg ttttttccat gctctgcaga tagcggttat
    21961 ctttccagag cgcaaagtga caatcatggt tgctgcaata gaagttgggt ttgctttcat
    22021 ataccaggct tccacatacc ggacatgttc caatgctttc tctggtctga aatcttcttg
    22081 tttcttcttc ggaaatcgca tcgcatccat tcagcatcat ggtcagcatg tttttgatcc
    22141 cggtcataaa ctgttccggt gcaatctctc catgctccat caagagcagc tggttttccc
    22201 attctgcagt catacttgca gatttcagga agtccggcag gatctccaca aggacttttc
    22261 catcctctgt tggaagaatc tgttttcctt ttcgggtggc atactgggaa tagatcagtt
    22321 tttcgatgat accggctctt gttgccggag ttcctaatcc tttcttttct gtatcttcat
    22381 cgaattcctt atttccagca gtttccattg ccgcaaggag cgtatcttca ctgtatggtt
    22441 ttggcggtga tgtgaaatgt tctgtctttt ctgcagctac agcatagaaa gtctgtccct
    22501 gggttacttt cgggatcttc tctttcattt cctgatccgg atctacgatt gccatgcggt
    22561 ccttattctt gaagcagttt tcaaagagtt tccatccatc ctgcaacaca gtttttcctt
    22621 ttgctttgaa gatttctccc tggcattcca cttcaatctc tgtttcctgg taaacgtgct
    22681 ccttactcat tgccatgacc gtgtgaactg caatcaggaa aagaatcttt tcttcccaag
    22741 atttcaattc atccagatgg caggatgaaa gctccatcgt tgggatgatt gcatggtgat
    22801 ctgtcacttt gctgttattc atgactttct tcacatccgg ctgttccggc tgatcaaaag
    22861 gacctgtcag ttgatatttc tcataaatct gacgaaccac atttcttgcg gtctgctcca
    22921 tatcttcggt cagatactgg ctgtccgttc ttggataagt gatcagtttc ttttcataca
    22981 ggttctgagc ggtatccagt gtctgtttgg ctgtcattcc gtagatacgg tttgcttctc
    23041 tctgcagtgt ggtcagatca taaagctttg gtgcttttac tttcttttcc gtttctttta
    23101 ctgctgtgac aatagcttca cttccttggc atctgcttct taactgttcc gcctcatccg
    23161 gatcaaagat ttttggcttt acagccggaa ttccatcaca atcgagttcc acattgaaat
    23221 acttttcttt ctggaaattg ctgatctgtc cggcacgttc caccaacatg gcaagtgtcg
    23281 gtgtctgaac ccttccaacg gtcagctttt tgaagtactt tgtggtgtaa gctctggttg
    23341 cattcattcc taccagccag tcagcctgag aacggcatac agcagcttcg gccagatgtc
    23401 ggtattcctc tgcggatctc agatgctgca ttccatcaag gattgctgaa tcttccagag
    23461 aactgatcca taatcgtttc accggctttt tacttccgga taagtcatag acatgtttga
    23521 agattaattc tccttcacgt ccggcatcac aggcatttac gacgtattca atttccggac
    23581 tgttgagcag tctttttaag atatagaact gatctttctt atcttctgag actgtaactt
    23641 tccagtcttt cgggatgatc gggagatctt catatctcca ctggttaaat ttctcatcgt
    23701 aagcatccgg tgaaacatat tcggccagat gtccgaagca ccagctgacc atacagtcgg
    23761 ttccttgtaa atatccgtct tctcgttcct gtgctccaat cacttctgcg attgctcttg
    23821 atacacttgg tttttctgca attactaaat acaagatgta ttacctcctt catataacga
    23881 aacggagaga gcatgtttta cagccccctc cgctaaaaaa gtttatttat ttttcatttt
    23941 cttcaaaatc ttcgtcttca gactcttcct catccggaac ttcttccagt ccacctgttt
    24001 ccaaaccttc cggctgatca tcctcatctt cctctttttt aggtttatag atcttgaagt
    24061 agtagtaagc tgccacgccg ccgagagcca aaatcaggat tgttgccatt gcacccatat
    24121 tggtttttgc agatgatgtt ttctcaggat caacagtagc ttccttgtct acatcctcat
    24181 tatttgtctc atccagcaca accttcgatg tatccggctg tggtgttaca acagcagctg
    24241 tactgtcttt atccagaaac tcggacagat cattctcatc aatctgagat aacatataga
    24301 cattctggga tgtggcactg cggtcgatca cgatatagaa agtgttgtta ttcttcgttg
    24361 taaccgtaag aaattccttt gtggaatcat cggtaatgtc atc
//
LOCUS       DAFENC010000174        10786 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.guided.069, whole genome shotgun sequence.
ACCESSION   DAFENC010000174
VERSION     DAFENC010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10786
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.guided.069"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(204..2162)
                     /locus_tag="LP493_003045"
     CDS             complement(204..2162)
                     /locus_tag="LP493_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBL2135109.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(2159..3031)
                     /locus_tag="LP493_003046"
     CDS             complement(2159..3031)
                     /locus_tag="LP493_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBL2135110.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(3373..4245)
                     /locus_tag="LP493_003047"
     CDS             complement(3373..4245)
                     /locus_tag="LP493_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBL2135111.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            4373..4942
                     /locus_tag="LP493_003048"
     CDS             4373..4942
                     /locus_tag="LP493_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBL2135112.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            5009..5746
                     /locus_tag="LP493_003049"
     CDS             5009..5746
                     /locus_tag="LP493_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBL2135113.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            5977..7245
                     /locus_tag="LP493_003050"
     CDS             5977..7245
                     /locus_tag="LP493_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBL2135114.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            7732..8196
                     /locus_tag="LP493_003051"
     CDS             7732..8196
                     /locus_tag="LP493_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBL2135115.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            8180..8809
                     /locus_tag="LP493_003052"
     CDS             8180..8809
                     /locus_tag="LP493_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBL2135116.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            9163..10641
                     /gene="msr(C)"
                     /locus_tag="LP493_003053"
     CDS             9163..10641
                     /gene="msr(C)"
                     /locus_tag="LP493_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HBL2135117.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            10688..>10786
                     /locus_tag="LP493_003054"
     CDS             10688..>10786
                     /locus_tag="LP493_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBL2135118.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQD"
BASE COUNT         3485 a         2005 c         2173 g         3123 t
ORIGIN      
        1 agaggttgta aaaaagctgt tctgcatcaa gtaataagaa gagtcaaata aaaaatagct
       61 cttcatatgt tacgtttggc tggacttatt accgcggagt tggcaggaga acgccgtttt
      121 tattcggaaa aaggagctga gacaagattt ttgtctcagc tcctgtttgt ttatcgataa
      181 aaaagtctgg ggaagacgat ggctcaggct ttgttggaaa cagagccgat tttatcattt
      241 gcttttacat cacgtgcggg ttcgatttct aagctttgga ctttgtcgcc atttgtgaat
      301 acaacgacca tatccgtgtt tttgcctgca gattgaatag cggcaagatc aactaaagca
      361 atcaattgac ctcttgcgac tttttgacct tcttttacat ataaagtgaa tggttcgcct
      421 tttaagtcaa cagtgttgat gcccatatga agcaagactt cgataccagc atctgtttgg
      481 attccgacag catgtttcgt tgggaaaatg tttgtgatcg taccagcgat tggagagaag
      541 atttctccat tttctggtaa tacagcatag ccgtcaccca tcattttttc cgcgaataca
      601 tcatctgaaa cttcagtgat tggaatcagt ttcccatttg cgatagcgta aatatcttgt
      661 tcgatcgttc caccggcaaa tgtttctgtt ttaaccacgg tgtttgtttg tgcaggtcgt
      721 gttgcagcac caccatgtag ttttgccatc tcatctgcaa cgaattgtac ttctgtacct
      781 acgatgactt gcgcattttt tccgtcgatg atcttcatac caggtacgcc agtggctttg
      841 attttatttt gatcgatcag gcctgtatct ttgacttgca aacgaaggcg tgtagtacag
      901 ttatcgatcg aagttacatt gtcggctccg cctaatgcag cgtagatttt gcttgcttgt
      961 gccgcatatt tattgtctga attagtcgtt gcagtatcgt catctgaaag atctgcttcc
     1021 tcgcggccag gagtcatcag atggaatttt ttgatagcaa agttaaagcc aaagtagtaa
     1081 atcactgctg ttactaatcc ttggacgatc aacatcaatg gctgattcgc aatcggattt
     1141 ttcaaagata ggaagtaatc gacaaatccg gcactaaagg caaatcctgc tgtccaatgg
     1201 aagaatgcac tcactgctaa agaaatccca gtgaaaattg catgcaagac atataatggc
     1261 caagcaacga acataaatga gaattcaagt ggttctgtta caccagtaaa gaatgaagca
     1321 aaagctgctg ctaacatcaa ggaagctgtt tttgctttgt tttctggacg tgcatttctg
     1381 taaatagcat atgctcctgc tggaagcccg aacatcatga ttgggaaaaa tccagcttga
     1441 tacattcctg ttacgccttt tgttccttca gaagccaaaa atttaccaat atcattgatt
     1501 cctgctacgt caaaccagaa cacggagttc attgcttgat gcaatcctgt agggatcagt
     1561 aaacggttga agaagccata aagacctgca ccaccccagc ctaaactcaa aatgaattta
     1621 gcaaaagaaa ctaaagcaga gtaaaccgga ggccatacga gcagtagcac tgcactgatc
     1681 agcaacatga caaaggcagc caagattggc actagacgct tgccgctaaa gaaagataaa
     1741 gccatcggta attttgcttc gtggaaacga ttataaagag ctgccgcaat caatccggca
     1801 ataataccaa taaatacgtt actgatctga gcaaaagatg gatcaactga ttctggtttg
     1861 atattcaata aagtagctac tgaatcagtt tttaaaacat ttactggaac ttcaaatgcg
     1921 accaaacctg ccaaggcagc agcacctgat ttgtccactg acatccctag tgctaaccca
     1981 acggcaaaca gcaaaggtaa ttgacctaaa actgcgttac cgccagcttg taaaaaatga
     2041 gcgacaatgt cgttactata agatgcccac cagtttccga tccctactag taaagcagca
     2101 gcaggtaaga ccgcaactgg aagttgaagg gaacgtccca ttcgttgtag atatgctttc
     2161 aatttttttc ctcctcatga ttgttaacat ttgtttgtac gattgcgctt cttaaacgct
     2221 cgatatggat ggccaagtaa cccagttctt ctttcgtgat cgcgagctgg tattctttgg
     2281 tcagcaacac acggattttt ttagaaatct tatagctttc tgggtatttt cgtttgacca
     2341 tttctacgat ttccgtgtct aaaacagcat attgttgcgc atgggttcgt tgtagaagca
     2401 gtcgtaaatg attcaccagt cttgaataat tcagtgaaaa tggttctgaa tggatatctg
     2461 tttccaattc tgattccact aaatggatga tgtcagatac aatcgtcact tcacggatac
     2521 tgcgatggtt attgttccga ccgcttcgtc cgctgtgaat atggattgcg atatatcctg
     2581 cttcgtcata agtatatgga atcccaagct cttttgtcag atactctact gcccattgag
     2641 caatactgaa ttcatcactg taaagcactt cgatttctct taaaagtttg ttgcggatga
     2701 cgataccgtt attaatgttc tccgcagaaa aagcaatgtg gtcggtcaaa gcgatcaata
     2761 catgttcatt caacttttcc atcaaaacag tttccgcatg atcaatgatc gtttctgctg
     2821 caaataaaaa gcgttcatca atctgattaa gtaaattttg caacttgatt tgaccttctg
     2881 gttccatgac aaatatccgt tcgacatcac gatcaaaaat caaatcattt ctttttctgt
     2941 caaatccaat cccttttcca atagctactt tttcctgtcc accgtcatct accaatactg
     3001 cattttgatt aaagatcttt ttgattttca tgcgcgcacc ctttttgaag atttggtttt
     3061 cacgtttgct agaccagttg attgcggcca aacaaaaata gacacgaaaa acctcctagg
     3121 gaaaccatgt tcctcagaga tttttcatgc ctagtatgat ctagtcacat gaaacgaatt
     3181 attgttaacg taatcaattt tatatagaca gttatgtttt gtcaattctt tttttataat
     3241 tatagtaatt tactggaatt atcagaaata aaaggaagga acaaattaag aaacttatgt
     3301 tatttaatca ttggatcttt tgcttaactt attcgttgtt aaaaagctga aagcgaagga
     3361 aaaaaactct acttaactgt atttctccgt taggacatct aaaaatttac gagcagcagg
     3421 agaaagaggc tggtcttttt tccaaatgag attcagtgaa gcttgtaatg gcggatcgag
     3481 tgggatgaat actttttccg tcccataagt attgatgatc ccatctagag ctaatgcacc
     3541 aaaagtcccg ttatcgacca tcaaagaagc attgtacaat aagttatatg ttccgacgat
     3601 cgataactga tctatgctga aacctagcca ttcagctagt tgactgtcca ctgacgtttg
     3661 ccgggaaatg atcaaaggaa cagttttcag ttcctgcgga tggatgactg tttgctttgc
     3721 taaaggatga ttccgatgta tcaaaagtcc ccaacgatct tgggctggca gtcgaaatga
     3781 ctggtatttt tgtttgtttg tcggttcgat tacgagtcca aaatcaagta atccgctatc
     3841 cagtttgtct atgatatcat ctgcattccc gctatataaa tgaaactgga tatcaggatg
     3901 cgccttgatc aacgaatgaa ggctatcaga aatgaaagag attgctttag tttcgcctcc
     3961 gccaatgtag atttctccag agatgattgc gtcatttgtt aaattgttcg ccgttttttc
     4021 taccaacgac aagatttctt ttccttttga ataaagatat cgaccagaat ccgtcaactg
     4081 tatctctcgg gagcctcgag tgaaaagtgt cacaccaagt tcttcttcta aatctttcag
     4141 ttgttttgag agagtaggtt gcgtgatatg cagagatttt gctgctcggc tgatattttt
     4201 ttctctagct actgctaaaa aatacgtcag tatacgaata tccatttttt ccctcctgtt
     4261 tttaaaaaag cataccacta agtatagtta aaaggaatag ttaagtatgt tttataagta
     4321 ttagacatca taagccgtcc gttataaagt aaggataaaa ggagggagca aaatgacaag
     4381 cctcatcgaa aaacaaatcg tcaataaaga gattcgagta acggatccgc tctttgaagt
     4441 gatccatcag atccaagcgg aaaacgaaga gcctttagca gcgctgaata ctgggtacca
     4501 tgaaccagca gatatccgca aacggctaga aaatatcatt agtgacaaag tagatgatac
     4561 ggtgactgtt ctgctgcctt tttatacaga tttcggcaaa catattagta tagggaaaaa
     4621 tgtctttatc aatcgtcaag tgatgttcgt tgacttaggt ggcatctgtt tagaagattc
     4681 agtattgatt ggtcctcgtg tcaacctcat cacggtgaac catctaaccg atccaaaaga
     4741 acgaagaggc ttgtcagtaa agccaatcca catcaagaaa aatgcttgga tcggagcagg
     4801 agcaactatt ctgccaggcg taacgattgg cgagaatgcc attgttgcag cgaatgcaac
     4861 tgttacgaaa gatgtcccag acaataccat cgttgcagga atccctgcca aaatcgtcaa
     4921 acctgtcgaa cggattattt gaacagtaag atgaaataag agatagtgag tataagcaag
     4981 agatttttca aaacaggagg agaatagaat gaatgattta tcagaaaaag tgattgtcat
     5041 catgggcgct tcaagcggaa tcggtgaagc aacaacgaag ctattagcag aaaaaggggc
     5101 taaactagtt atagctgcac gccgagaaga tcgcctaaaa gcaataaaag aatctttacc
     5161 agaagctgag ctatatattc aaacagcaga tgtaagagat tttgcacaag tccaagcagt
     5221 tatcgattta gcgatggaaa agttcggtcg aatcgatgta ttgtacaata atgcaggaat
     5281 catgccaacc gctccattag ttgaaggtca ccgtgatgaa tggcaaaata tgcttgatat
     5341 caacatcatg ggtgtgttaa atggaatttc cgccgtactt ccaatcatgg aaaaacaaaa
     5401 atctgggcat atcatttcaa ctgattctgt ggcgggacat gttgtttatc ctgattccgc
     5461 cgtttattgc ggaacaaaat ttgctgtccg tgcaatcatg gaaggattac gtcaagagca
     5521 acggcaaaat aacatcaaat ctacgatcat ctctccagga gctgttcaaa ctgaattata
     5581 tcaaaccatc agcgacaaaa aggctgctct tgaacttcat gaagcgcaaa aagaatgggg
     5641 attaacatct gaagatatag cttctgctgt agcatttgcg atagaaacgc cagaccggat
     5701 gtctgtcagc aacatgatta tccgtccgac gacacaggaa gtataatcca taacggataa
     5761 tatccagaga gaattacttg ttaaatagtt attcaaacga ccatcaattt aaggcgtgaa
     5821 tggagaagaa tattcttcat ttacgtcttt ttatgcagaa aaagcaaatt tattaaaaag
     5881 aaacaaatgt tatttaaata tggacattga cttgctttta cttttttagt tacactgtta
     5941 tttaggaaaa gtttcataat tcaaaggaga aaaaagatga aagcaaagaa tttattattt
     6001 agcgttattc ttttaggaaa tctagcagtt gccaacacaa cagtgctagc tgaagaatcg
     6061 acagaaactg tcgcaactca gacatcgagt tcttcagaaa caggaattga aaacgataca
     6121 gaaagtactt tgcagtcagc tactgtctca gaaaatacaa tttcaaccga agaaccaaca
     6181 actgaaacaa cagaacaaac acaaaccgaa gacagtacat cagcagaagc tcagaacaat
     6241 ccagagaatg cagaagaaat cacgaaccaa ttgacagatg ggcaaacatt gacacatacc
     6301 catcaagcag atttgtctga attcgaaaac tatactggct atgcttttta tgctcgctca
     6361 tctgctaatt ctcaacaagc gttcattgat agtattgcct caactgcaca aagtttggca
     6421 agtgccaatg acttatatgc atcagtcatg attgctcaag ccatcgttga aagtggctgg
     6481 gggaacagta ctttggcttc tgcccctaat tacaatctat ttgggattaa aggaagctat
     6541 aatggccaat ctgttacgat gcctacttcg gaatatgtga atgggcaatg gattacggtg
     6601 aatgccgctt ttagaaaata tccttcgtac aaagaatcat tgcaagataa cgtaacggta
     6661 ttgaagacga cttcttttca gccaggcgtt tactactatt ccggtgcatg gaaaagcaat
     6721 acgaactctt acaaagatgc tacggcttgg ctaacaggtc gttatgccac tgcgcctaat
     6781 tatggttcta cattgaacaa tgtaatcgaa acctataatc tgacacagta tgatacagca
     6841 ccaacttcaa cttctccgat gtatcgtctg tataaccgtc atacaggaga acatttatat
     6901 acattgaatg ccggagaaaa aaattatctg ccaactgtag gctgggaata tgaagggatt
     6961 gcttggcaag caccaaacag cggacaacct gtctaccgtt tatacaatcc ttacagtgga
     7021 gaccatcatt acacaatggc acaatctgag atcaactctt taacaaaaat cggttggcgt
     7081 tatgaaggtc taagttttta ttctggtggt tccaagccaa tttatcgact atttaatcca
     7141 aatgaaaaaa ctggtaccca tcactatacc ttgagtgcta aggaaagaga ttggctaaca
     7201 ccgatgggct ggagatatga aggaatagga ttttatggtt attaaaaaga ggtagtgaaa
     7261 aagctgccct gcatcaagta gtaagaacag ccaaacaaaa acagattttc atgttttttg
     7321 tttggttgaa cttattaccg cagatgcaag tttttgaaca ccgtttactc aaaaaaggtt
     7381 gtgacaacat cttgtcataa cttttttatt actgtttaag catactgatc caatttctaa
     7441 tattcgacgg gattcttgca aaaggcgatt tcggaaattt ttggcggtgt aaaattatct
     7501 actgcagaag agctatcttc tatagtttga taagaatcaa taatcttggt tttagcgttg
     7561 tgctttcttt atcatttttt ccgttcattc tacaaaaaat ttcttttctc tatacttttc
     7621 tattgagagc gtttttttta ttacacagct gattctttga cttttttctt tttttattct
     7681 attattgaca agtcaatcgt tgacgagtca attattagaa aggaggaaat tatgtcttta
     7741 gaagagatta gtcacctttt atatcaaatc aaattagccg atcaaaaaat cgtccagatc
     7801 tttgaagaaa atatcggtat aagtcttact agatacgaga tcatgatgag actgaaagaa
     7861 gaaaatccat tgctacaaag cagtttgcaa gaaaagttgc agattgatca aggagcagtt
     7921 actcgtcatc tgaaggtatt ggaagcaaat ggctatgttt cgcgtcagag aaatcctcag
     7981 aacaaccggg aagtgtatgt agcgctaaca gaaaaagccc agaagaaaat caagcattgt
     8041 gaaatggacc ataaagatac aggttccgtg ctatccccgg ctttcagcga tgtagaaatg
     8101 aaacaatttc taacactttt agataaattg aatacccaac tttgcaatat aacaacagaa
     8161 acgaaagagg ttaataataa tggaacaaaa aaatgatttt tcaacaatta tgactggtag
     8221 aagatccgtt cgcgtatatg atgaaacata caaaatccca cacgaagaaa tgctggaaat
     8281 gatcaaagaa gcgacgactg caccttcttc tgtcaatatg aaaccatggc gctttgtggt
     8341 cgctgaaagc gaggaagcaa aagaaatctt gcgtcctttg atccgtttca atacgagaca
     8401 aaatgatact tcttctgcaa tggtcatgat ttttggcgat atgcaatgtt acgaatatgg
     8461 cgaagaaatc tacaaccaag cttacgaatc agggaagatg ccaaaagaag tcagagatca
     8521 acaattagct gcgatcattc cttattacaa gagtttttca agagaagaaa tgaacgatgt
     8581 agtcaaagtc gattctagct tagcggctat gcaattcatg ttagttgcgc gtgatcatgg
     8641 ctatgaaaca aatccaattg gtggattcga agcagatcag ttggcagagg catttggttt
     8701 ggataaagac cgttatgttc cagttattat tttatcaata ggaaaagcgg tagaagaagg
     8761 ttacgagtct gttcgtttag caccagaaaa gatcactatg ttcgaataaa aggttttcag
     8821 ttactattca gtagctattg ctttttttga atcgtgtgtg gtaacctaat aaaaaaggag
     8881 gtcggaaaaa tgactgcatc gatgaaatta cgtttcgaac ttttgaataa caactaaata
     8941 aattcaaaag acatgtataa acaacaattt catggatgga gtatgtccat tttttcgaac
     9001 gacagtagaa taggtgaaag ctatgacaga tttggtgatt tagtcatagt tatttcgttc
     9061 agagtaggaa aagatgtgat gcagtttttt tgcaaacaga tttttctgct cttttttagt
     9121 atcgataatt gttgttttac atgaaatagg agtgtaaaac atatggaaaa tttagcagta
     9181 aatataacaa atctacaagt cagctttggc aaccagctag aactatctat tgattctctt
     9241 cgtgtctatc agcaagatcg tatagggatc ataggagaaa atggtgtcgg taaatcgact
     9301 ttgctcaaac taatagccgg tgaacttttt cccgatcatg ggaaaatcca aacagagatc
     9361 accttcaact acctgcctca attaacctat ctcgctgaag caaaggacct aaatttggaa
     9421 ttagccagtc atttccagtt aagactggaa gaaacttcag agcggaaatg gagcggaggg
     9481 gaagaacgaa agatcgagtt gatacgtctt ctttcttctt atgaacaagg gatgcttcta
     9541 gacgagccaa caacccatct agatagaaaa agtattgatc gactgattga agagcttcgt
     9601 tattattatg gtacgctggt ttttgttagt catgatcgct attttctaga tgagctagca
     9661 tcgaaaatct gggaagtaaa agacggagaa atccgagagt tttcggggaa ttatagtgcc
     9721 tatctcactc aaaaggaatt ggagaaaaag actcagctac gagaagcaga gtcgatcatg
     9781 aaagagaaaa aacgattgga aaaatcgatc caagaaaaga aaaaacaagc ggaaaagttg
     9841 gaaaaagtgt ccagtaaaaa gaaaaagcaa caaatcagac tggatcggtt gtcttcctct
     9901 aaacaaaaag acagtgtaca aaaagccatc caaaagaatg cgaaaacatt agagagaaga
     9961 ctccaaaaaa taggagaaac aaccaagccg cagcagatga aacaaatccg ttttccagta
    10021 ccaaaatctc ttgaactcca cagccgctat cccatcatgg gacaaaatgt ccaattggaa
    10081 agaagtggga gaacattact ggtaaatggt gattttcagt tttctttagg taaaaaaatc
    10141 gcgattgtcg gtgaaaatgg ttcaggtaag acaaccttat tagaacatat ccgcaaacaa
    10201 ggagaaggaa tccttctctc tccgaaagta agctttcaag tatatcagca aaagggttat
    10261 caaatgacat ctgaagaatc catcattcgt tttgtcatga gacaaacaga gttttcagaa
    10321 tcgcttgtcc gtagtttgct gaatcactta gggtttgctc aggaaacttt gacgaaaccg
    10381 ttatgtacat taagtggggg agaagcgacc cgtctgacga ttgctttgct ttttactaag
    10441 ccaagtaatg tgttgctgtt agatgaaccg actaatttta ttgatatggc aacgatcgaa
    10501 gctttagaga agctaatgca aatatatccg ggaacgattt tgtttacttc tcatgattct
    10561 tactttgtcg agcgtacggc tgatgaagtt tatgaaataa aagggcagaa aataaaaaaa
    10621 gtacttacga gaaattttta aatgtgctac gatgattttc gtgacaaatt taaaggagtg
    10681 gtacagattg cctacaaata aaaaagaagg aataattttt acaacaatga tgtgtttttt
    10741 gatggtcttg gggatgagcg cgtataattt atggctgcat caagat
//
LOCUS       DAFENC010000175        10095 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.guided.072, whole genome shotgun sequence.
ACCESSION   DAFENC010000175
VERSION     DAFENC010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10095
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.guided.072"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            complement(134..577)
                     /locus_tag="LP493_003055"
     CDS             complement(134..577)
                     /locus_tag="LP493_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HBL2135119.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(795..2135)
                     /locus_tag="LP493_003056"
     CDS             complement(795..2135)
                     /locus_tag="LP493_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBL2135120.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            2404..3300
                     /locus_tag="LP493_003057"
     CDS             2404..3300
                     /locus_tag="LP493_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBL2135121.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(3450..4391)
                     /locus_tag="LP493_003058"
     CDS             complement(3450..4391)
                     /locus_tag="LP493_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBL2135122.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            4517..5638
                     /locus_tag="LP493_003059"
     CDS             4517..5638
                     /locus_tag="LP493_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBL2135123.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            5896..7398
                     /gene="eat(A)"
                     /locus_tag="LP493_003060"
     CDS             5896..7398
                     /gene="eat(A)"
                     /locus_tag="LP493_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBL2135124.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            7426..7992
                     /locus_tag="LP493_003061"
     CDS             7426..7992
                     /locus_tag="LP493_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBL2135125.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            8203..9264
                     /locus_tag="LP493_003062"
     CDS             8203..9264
                     /locus_tag="LP493_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBL2135126.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            9267..>10095
                     /gene="murQ"
                     /locus_tag="LP493_003063"
     CDS             9267..>10095
                     /gene="murQ"
                     /locus_tag="LP493_003063"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBL2135127.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     "
BASE COUNT         3393 a         1844 c         2043 g         2815 t
ORIGIN      
        1 ctgttcttat tacttgatgc agggcagctt tttcacaacc ccttattcac ggcgttccag
       61 aagtagcttc ttcttatttc ttgaagctga taacttctgg aacatcctct ttttttattt
      121 ggacggataa tggtcattcc atttctttga tcattttttt cattttgtcg atctcttctt
      181 cttgtgcctg aatgatttct tccgctaatt tttttacttc aggatctttt aaatcagctc
      241 gtttacttgc caggatagcg atagaatgat gaggaatcat ggccttcatc caagctgtgt
      301 cgttgacagt agtttggctt cgtaccataa acaaggaacc ggcaaaaaca agaagactag
      361 cggctaagat cataacattt atctttttgt tttcatacat tttccacatg aacaacagca
      421 tgatgactgc catgactgca cccatcatca acgccatgaa tactcgtgta cgactgaaga
      481 agatatgatc gagcgcatag acattcaagt acatcatacc aaacataact accgttgaaa
      541 caccgatcat caacaaaaac ttccaatact ttttcattta aaacaaactc ctttttttca
      601 ttcctttctt ctatcatgtc atgagcatgg agaacaatca attattttgc acagagggtt
      661 tttgaacacc gtttaccaag aggtcatgag actgtttatt cggaaaaagg agttgcaaca
      721 agacttttgt cacaactcct ttcttcaata gctccatcta ttccacataa ataaaataaa
      781 attttctatc gatttcattc attcgtcaat acgaacgcat cattcttttt ttgataactg
      841 aaataaatga acaggtaaag caggccagtc aatacagtta ccccaatgga gttcgtgaac
      901 aggataccaa ggaaaatcaa tcctaagaca gctaatgcaa aaaagctgat tcctttatcc
      961 cataatgttc cttttcttag tgccagtaca aaggatgccg cactgataat gatccagatc
     1021 aataatactg tatacgaaag ggaacctgcc agatagccaa ataatttgtc accgacaaaa
     1081 taagaaagag ctacaccaag ataaagaaca ctggtacaaa ataaaacagc acgttgcggt
     1141 acttgatgct tgtttaaaac agctagtttt ctagaggaac cttttcgatc cttcaaacgg
     1201 aagaacaaaa ttcttgaaga tgcatacaca cccgaattga tagatgagaa caaagcaagg
     1261 acaatcacaa aattgacgat atccgctgca aatgggatat tcattttttc aaataccatc
     1321 acaaaaggac tgacattcgt gcctgctaaa gtattccaag gaaaaagaat caaaagcaaa
     1381 aacaaaggaa tgatgtaaaa ggaaatgatt cttcccatga cacctttgat tgctttagga
     1441 atcgcacgtt taggatcatc tgcttcgctt accgtgatag caatcagttc agaaccgccg
     1501 taagaataga taactacaag caaagaactg atgattccct tcataccatg aggagtaaac
     1561 ccaccatggt cagtcaattg ctgaagggta gggaaaacgc ctgtgcccaa catttgctga
     1621 ccgacaagat aagtagcaaa aatgatcagt aagataatga cactgatttt agcaaaagcc
     1681 agccaatatt ctgtttctgc gaataaccgt accgaataaa gattgatgat cgtagttaaa
     1741 acagccaaca taaaaacaaa tacccaggct ggaatgtgcg ggaaccacaa ctgcaaaaag
     1801 gaagcagctg caacagcttc agcgatgata ttgataatcc acatagacca gtagacccaa
     1861 tcagtaaaat cagcagaatg agcacctaga taagggcgta tcaaaccaga taatccgtga
     1921 tgcgtgtcgc caccgcttaa aacgattttt cccagacctt tcatcacgat atataaaatc
     1981 agcccaccaa tcaaaaaagc aatcaataca gaagggccgg cgatcccaat cgcttcgcca
     2041 cttcctttaa atagacctgc accgattgct ccacctaaag ctaacatggt gatatgtctg
     2101 gagctaagtt gttttttcaa ttttttatct tccataaatg acctctttct tttaaattca
     2161 caatcaaaat ttatattaag aataaatagc aatatttaac aatgactaat gataacaaat
     2221 tttcagacaa ttacaactat tcagaaaact tttaggcgaa ttttaataga agaatgattt
     2281 atttcatcat attttcatac aaatgttaaa ttttcataca aatataggaa acgttttact
     2341 ggctttttac tatttaaaca ggctatcata ggaaaaagtg acagagaaag tgaggcggaa
     2401 aagatgaaca aaaatgacgt actgctagtt gcaaaaaata aatcacttta ttttttgcct
     2461 tccatccgct ctttagatgt ttggtccgga aaagatttac tacagtcgga attcattaaa
     2521 tcagctagac aacagttggc aaattatcag ctgatcgttt ttttagatta tggatttgat
     2581 atggagatgg ctcgacgcgt gcgcccattt accaatgcaa aaattgtgtt atttttttgg
     2641 aatcacttca aagcagaaca cgaggcgatg ctgaagcagg cacaagatga accggcaatc
     2701 gatgagattt atcattttga ttttttggaa gcaaaagaac ttgggctgaa acataatagt
     2761 tcattttatt cgaaacatat gaatttttct tctagcgaac caaagacgga tctatttttt
     2821 ggtgcaacga ataatgggag aaaagaacga gcagaaagct ataagcagga atttataaaa
     2881 agagatgtta cgaccaacta tttcattctt ccacatcgag ggaatgaaca acctggatat
     2941 cttacttatg aagagtacct gaaaaaaaca ggggaatcgc gcgggattct ggaactgttg
     3001 cgggagggtc agcaaggagt gactttgcgg acatttgaat ccatgtattt tcaaaagaaa
     3061 ctagtgacgg ataatcaagc gattgctcat tatcattttt atcgtcctga aaatattttt
     3121 ttgcttcgag aacgtgattt agatgaatta ccggaatttc tgcatacacc atttaagcca
     3181 atcctatcag agctattgga attttatgat gcagaaaatt gggcaaaacg atttatcact
     3241 aacgattcca ctatttatga gcaatacgaa tatgacctct cctctgttga aaacaaataa
     3301 aaaacctaca ttttgaagag attatgtact gaaacaaaca agcacaattc ttatggcatc
     3361 atgagagttg tgttttcttt ttgatctttt attgggctta aaaaaagaga accagctgct
     3421 gattcagctg attctcatca gagagccttt tattctgcgc caaggattcc ttcttttgca
     3481 tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt ttgtcctttt
     3541 cgccaaatgg caccattgat gtagtcgatt tcagtcaaac gatggttttt gatcaggtct
     3601 tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga agcaatatgt
     3661 tggtacactt cttcttgatc tagtatgatt ccttcttttg ctgcgataga agcaaattca
     3721 gatacgattg ttcgaaccat gctctctgcc gctttttgcg cgcctagttc agcaatatta
     3781 caatccaaaa tcgtgcataa accattcaat gttccattta cacaagcttt tcgccaaatg
     3841 gaataacgaa cgttatggct atagatcgga tttaaatttg cttcttgaaa gacttctaca
     3901 actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat ttctccatca
     3961 cctaacaatg tgacttttcc gggaccagct agaccagctg tccacatcgt gatcccaaat
     4021 aagatatttt tctttggcac atatttttcc agtacatctt catgacctaa tccatttagt
     4081 aaacacaaaa cataagtatt gtcagtaata atggattgga tcgaacaaaa catatcatct
     4141 aattgattgg cttttgttaa tgctacgatc aagtccacgt gttcgttgct ttcgatgatt
     4201 tcttctggtg aatagattgg cagttttgcg accacttctt taccgttaaa gtcagcaatc
     4261 aacccatttg tacgaatggc ttcaatgtga gcaggccaac gatcgatcaa gaggacctca
     4321 tttccgcttt gatgtagcat caatccgatt cggctgccca ttgctccggc cccagctatt
     4381 gcgattttca tgttttttct ctcctttatt caatgagttc ccttttagta tatagaaaaa
     4441 tggaagaaaa tagcattgtt ttgtttgaaa aaaatgaaaa aaagtgtctt acttaagaag
     4501 aaagtgaggg atacagatgg atattttggc ggcaattgat tcatttaaag gaagtgcttc
     4561 ttcatttgaa ctaaatcagg cagttctaaa tggctgggaa gatcgtaaag gaagaaaaat
     4621 caatgtgccg attgcagatg gcggagaaaa tactgcagaa gcaatctatt acgcgctcag
     4681 gggaacatgg cgtaccattg atgggatgga tctcttattc cgtcagcgaa aaatcagcta
     4741 tttattgaca acttggcaag gaaaaaacac cgcagtcatc gaatctgcac aagcattggg
     4801 gttagatcta cttgataaac caacggatca aactatccga cttgcttcca gttatgcctt
     4861 aggagaactt attaaagatg cactgcttca agaagtagaa caaattattg tcactttagg
     4921 aggaagcggg tgtagcgatg gtggtctagg attactccaa tccttgggtg cttctttaga
     4981 agggtacaca gaaggaaatc ctttattatc tactaaaaaa cttcattttg atcgaagaaa
     5041 cgttcttgtt tctaaagtaa aattgattat cgctgcagat gttaccaatc catatacagg
     5101 tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaatagata cgacgctagc
     5161 tttcttagat aaacaagcag gaaagattgc tcagcaaata aaagatttct gggaggtgga
     5221 tttagatgat attccaggaa gtggagcagc aggcggtatt ggtggagccc tttttttgtt
     5281 gggagcgaag atggtttctg gtttcgattt agtcagccaa atcactggat tggaaaaaaa
     5341 gatcgaacaa gcagatgtca tcattacagg agaagggcgg atcgatcagc aaacgatcca
     5401 cggaaaagtt ccatacggtg tagcagtgct tgcaaaaaaa tatcgaaaac caataatcgc
     5461 tatttgcgga agtagagacc aagagctaga aggactttct gattttctcc caattgtctt
     5521 aagtattcat ttgggtccaa taggtttaga agaagcaatg gaacacaggc aaacattaga
     5581 aaaaacaaaa atcttaggac agacacttag cagatttttc accatcctcc cgaagtagtt
     5641 gacaaaatca ttttctttat gctatcgtaa tttcaaatat aggacaaagt gagggatccg
     5701 tgcattgaaa aattaagtcg attgatgaaa gctgcattca gactgtacct tgtggagaca
     5761 aggaagcagt gtgcagattt tcgggattgg cttggttttt tcgatgtatg ggtctttttg
     5821 tgtgtatcca acccttgcat cctctttagc cagttctgaa aataggactg gtcttttttt
     5881 acgaggtgat ggaaaatgtc taaaatcgaa ataaaaaatc tgacattcgg ctacgacagc
     5941 caaggcacat tattatttga acaagcaaat ctaaattttg acacacaatg gaaactagga
     6001 cttatcggac gaaacggtcg aggaaagaca actttactga atattctaca aaacaaacta
     6061 ccttatcaag ggcaagtaat ccatcagcaa gaatttgcct atttcccgca acagacaaaa
     6121 gataaagaac gtttaaccta ttacgtgtta aatgatatta cggattttga gatatgggaa
     6181 atcgaaagag agctccaatt gatgcaaaca gatcctgaaa tcttatggag agaattcagc
     6241 acactatcgg ggggagagaa gacaaaagtc ctactggcac ttttatttgt ggatgacact
     6301 catttcccgt taatcgatga accaacgaat catttggata tctctggtag aaaacaagta
     6361 gcggcttatt tgaaaaagaa aaaacaaggc ttcatcgtgg tcagccatga ccggggattt
     6421 atcgatgaag tagtggacca tgttttagca atcgaaaaaa gtcaactgga actttatcaa
     6481 gggaatttct ctatctatga agaacagaaa aaacttcgtg atgaatttga aatggctcaa
     6541 aatgaaaaat tgaaaaaaga agtcagtagg ctaaagaaaa cagcagctga aaaagccgaa
     6601 tggtctcgtt cccgagaagg agataaaaca aagaaacaag tcggattcat cgatactgaa
     6661 tctagacgag tgaataaagg agcagtgggt gctgatgctg cacggacgat gaaacgatcc
     6721 aaagcaatcg tgaatcggat ggagacccag atcagcgaga aagaaaaact attaaaagat
     6781 atcgaatata tcgattcttt gacgatgaat agccaagcgt ctcaccataa gcgactttta
     6841 agcgtagaag atcttcaatt agggtatgaa aatctgttat tcgagccaat tcattttaca
     6901 atcgagcctc atcagcgggt ggcgatttca ggtcctaacg gtgcaggaaa gtcatccatt
     6961 atccattatc ttctgggggc attcaacggc aaggttatag gagaaaaata ccagccaaaa
     7021 catctgagca ttagttatgc aagccaaaat tatgaagaca atcgaggaac gttggcggaa
     7081 tttgcagaga aaaaccaagt agactaccaa gcatttttga acaacctccg aaagcttggg
     7141 atggaaagag atgtttttca taacaagatc gagcagatga gtatgggcca acggaaaaaa
     7201 gtggaattgg ctaaatcttt atcacagcca gctgaactat atacatggga tgaaccattg
     7261 aattatttgg atgtcttcaa tcaagaacaa ttagaacaac tgatcttgaa cgtgaaacct
     7321 gccatgttac tagtggaaca tgatcaaacc ttcctggata aagtatctac tgagattatt
     7381 tctcttgaga gaatctaacc cttgtaatct caagaacaac aaggtatggt taaggggaac
     7441 tttgccaacg aaggagagaa tcacatgctt tatgtaacga gacacggaga aacaacttgg
     7501 aacgcacaag gattagtttg cggacgggca gatgtgccgc tgactgaaaa aggacagatg
     7561 caggcacaga aactagcaga aaaggtagta gatttgcctg ttccaatcac gaaaatcatc
     7621 cattcccctc ttcaacgagc aagagataca gcacaagcag ttgctgatcg tctcagcttg
     7681 ccgctgaccg ttgatgaacg attggtagaa atggattttg gggattatga tggactgcca
     7741 agcaaagatg agaactttca aaaagcacgt ttagcgttcg ctgtacgatt cccaaatggg
     7801 gagtcagtct tagatgtgta tgcacggatc gttcctttat tgaaagaatg catcgaagac
     7861 gaagaaaatg tctatctgtt agtttgccat aatgccttga taagagtgat caatgcttat
     7921 tttcatccga tgcctaatga ggggttcttt acattcatgg tagataatac agaattggtt
     7981 tcttatgagt aattatgttt ttgtgttatt taaataaaat atttcaaggc actgcttttg
     8041 cttagcagtg ccttttttag gttatgacaa ttcttttgat aatataaact caacctttag
     8101 aaatgaaatt taattatttt aataaaagta ttgaaatttt gtttctttag atatatactc
     8161 tagtcataga aatgaagacg gatacagaaa aagagggata atatgtttgg cttttcaata
     8221 tttatgaacg attctttgtc agaagagaag aaacagtata tccgccaaat ggcatccaat
     8281 ggctttgtcg gtattttcac ttccatgcat ataccagaag atgatgtttc ggcatatcaa
     8341 aagcgattga tcgaactagg aagcgaagcg aaaaagaata aactagaatt gatggtcgat
     8401 atttcaggag aggcattgga acgagcgggt ttttcattag aagatctaac gcctttgaaa
     8461 gcaattggtg taacaggttt aagaatggat tatcatattt ccaatcagca gattgccgac
     8521 tggtcacatc aattgaaaat cagtttgaat gctagcacga tcacgcctaa agatatcgat
     8581 gaattgaaag aagcagaagc tgatttctca cagattgaag cttggcataa ttattatcca
     8641 cgtcccgaaa cagggctgga caaagaatgg tatcagaaaa aaaatcaatg gctcaaaatt
     8701 caaggtctcc ttgtccaagg ttttgtacca ggagatacag agttgagagg cccactatat
     8761 caaggattgc caactttgga agaacatcga gggatccatc ctcttgcagg cgctctagat
     8821 ctattagcaa gtaacacgga tattgtttac atcggagatg caggtctgtc agaaaacgtt
     8881 caggagcaat ttgcttcttt ccaaaaagaa cagacagtct tgctccatac ggaacctgta
     8941 gatgaagaat tttacgaata tatattaggg aagcatacga atcggcaaga cgatgcaaga
     9001 gatgtcatac gaagcgtaga tgcacgtttt cgagagattc cgcctatccc agcaagaaat
     9061 acagctacgc gtatgaaagg gtctattact ttagataacg aaaagtattt gcgctatatg
     9121 ggtgagatcc aattaaccaa atatgatttg ccagcggatg aaaaagtgaa tgtagtagct
     9181 aaagttatca aagaagagct accattgatc aaccaaatca aagctggtat gaactatcaa
     9241 tttataagaa aagaaggaag ataaaaatga gcaaaatcaa tttagagaac ctaacaacgg
     9301 aacgcagaaa ccaagaaact tttggattag atgagatgag tatttctcaa gccgttcaac
     9361 taatgaacaa agaagatcag aaagtggccg ctgcggttga aaaagaactg acaagtatcg
     9421 aaccagtgat tgctaacacg attgagtcct ttaaaaaagg tggacgtctg atttatatgg
     9481 gagccggaac aagtggaaga ctaggtgtgt tagatgctgc tgaatgcgta ccgacattcg
     9541 gtgtagaacc ggaaatggtc ataggtctaa ttgctggtgg agaagaagca atgactgtag
     9601 ctgtcgaagg ggccgaagat tcttatgagc tagggcaaga agatctaatc aagctgaatt
     9661 tgacaaaaaa tgatatagtt attggtatcg cagctagcgg tcgtacacca tatgtgatcg
     9721 gtggattaga ttacgcaaaa tcgatcggtg ctgtcacagg aacgatttct tgcaataaac
     9781 aagccgaaat cagtaaacac gcggatttcc caatcgaagt cgatgcaggt ccagaatttt
     9841 tgacaggctc tactcgattg aagtcaggaa cagcacaaaa acttatcttg aatatgattt
     9901 ctactatcag tatgattggt ataggtaaag tattcaataa cttgatggtc gatgtcaaac
     9961 caacaaatga aaaactaatc gaacgctcaa aacgaatcat catgcaagcg acagaagctg
    10021 attacgaaac agctgaaaag tactttgaag aagcagatca aaatgttaag ctggctatcg
    10081 tcatgatttt gacaa
//
LOCUS       DAFENC010000176         7958 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.guided.083, whole genome shotgun sequence.
ACCESSION   DAFENC010000176
VERSION     DAFENC010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7958
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.guided.083"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            128..1564
                     /locus_tag="LP493_003064"
                     /pseudo
     CDS             128..1564
                     /locus_tag="LP493_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
     gene            1753..4200
                     /locus_tag="LP493_003065"
     CDS             1753..4200
                     /locus_tag="LP493_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBL2135128.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            4430..5497
                     /gene="rlmN"
                     /locus_tag="LP493_003066"
     CDS             4430..5497
                     /gene="rlmN"
                     /locus_tag="LP493_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBL2135129.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(5690..6793)
                     /locus_tag="LP493_003067"
     CDS             complement(5690..6793)
                     /locus_tag="LP493_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBL2135130.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            7345..7893
                     /gene="aac(6')"
                     /locus_tag="LP493_003068"
     CDS             7345..7893
                     /gene="aac(6')"
                     /locus_tag="LP493_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBL2135131.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2665 a         1358 c         1729 g         2206 t
ORIGIN      
        1 tttcttacta ctcgaaacta agcgactttt tcacaacctc ctttacataa ttttattttg
       61 ttgtggaagg ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa
      121 gagatgaatg gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc
      181 ttctgcagcg tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg
      241 ggatcgattt gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt
      301 agaccactat catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc
      361 ttaccgcttc tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca
      421 agctgggctc gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc
      481 tatgttgact ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg
      541 ggaatcacgt cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt
      601 ccgcgggaaa gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg
      661 ttatttgtta gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa
      721 ccatattgct aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc
      781 tggaaaaatc ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga
      841 aaatgttctg gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta
      901 tatgtgggga aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc
      961 aacgattgaa gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat
     1021 caattactat caaacggcga cgaatgcatt caatccatta aacggagttg gtgctggaaa
     1081 aatgaatacg acaggaaaaa aaggttcatc agaagaaact ggagttcctg gaatgtataa
     1141 aaaagttgag aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg
     1201 attaaggatc ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga
     1261 aaatggctta ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg
     1321 aatcaattac ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga
     1381 agtcctaggc tattgcacct ggtcttatac agatttgctt agctggctga acggttatca
     1441 aaagcgatat ggatttgtat atgttgatta agacgaaaca caagaaggat ctttggaacg
     1501 atataagaaa gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct
     1561 ttagttcaca tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata
     1621 aaatcattta gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag
     1681 ttctttcaaa caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat
     1741 gagggataat aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa
     1801 acgaaaaagc aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg
     1861 attttatttg ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac
     1921 ggctttcgga tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta
     1981 ggattttgga ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt
     2041 ggcggcatac tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa
     2101 ctccatactg gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata
     2161 aaacaaagtc aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat
     2221 tttacttact tcttgattgc acagcctgga agttatttag cagcagtgct attactggca
     2281 ggaggagcat tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca
     2341 attggagaac gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa
     2401 gcggcaaagg aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct
     2461 gcaaaagaag ctgcagaaaa agaagctgca gaatatgaga agaaaaaagc ggtgagccag
     2521 caaagggaaa atactgctga tgaatggcag gaaccagaaa atacagagcc ggagcagcta
     2581 agttttgttc caatcgacag ttttcaagaa aatatccatc ctgcgaatct agagaaacca
     2641 gtaccagata caccaaaaca gaccaataca gcagaaggtt tttcagatga gttgccagag
     2701 gatgacggta cctcattaga atttgagatt gaagcagaac aggaaaatca agactatgaa
     2761 ttaccgacag ttgatttgct tgattctata ccaactgtgg atcaaagtga tgagtataaa
     2821 aaaattgaaa aaaatatcgg cgtattagaa caaactttcc aaagtttcgg tgtcgatgcc
     2881 aaggtcgtca aagccagctt aggaccatcc gtcacaaaat tcgaagtcca gccggctgta
     2941 ggggtaaaag taagtaaaat tgtgaactta acagatgata tcgcgcttgc tttagcggcg
     3001 aaagatgtcc ggatggaagc accgattcca ggtaaatcac tgattggtat tgaagtacca
     3061 aatggaaaga tcagtatggt ttcctttaga gaaatcatcg aagcacaacc aaaccaccca
     3121 gataaattac tagaagtacc tttaggacgt gatgtttctg gacgggtaca aacggctgat
     3181 ctttcgaaga tgcctcactt actcgtggct ggttcgactg gtagtgggaa gtcagtagca
     3241 attaatggga ttatcacaag tatattaatg cgtgctaagc cccatgaagt aaaactgatg
     3301 atgatcgatc cgaaaatggt tgaattgaat atgtacaacg gcatacctca tctgttgacg
     3361 ccggtcgtga cgaaccctag aaaagcagcg caagccttac aaaaagtagt acaagaaatg
     3421 gaagaacgat atgaaaaatt cgcggcaacc ggagtaagaa atatttctgg ttacaatgaa
     3481 tttgttcaac agaaaaactt ggaaaacgga acgaaacatc caaccttacc attcatcgta
     3541 gtgatcgtag atgaattagc tgatttgatg atggtagcca gcaatgaagt tgaagatgcg
     3601 attattcgtt tagcgcaaat ggctcgggca gcggggattc atatgatcct agctactcaa
     3661 cgtccaagtg tggatgttat cacaggaatc atcaaagcaa atgtaccttc cagaatggca
     3721 tttgcggtat caagcggtac agattctcgg acgatcattg attctaatgg ggcagaaaag
     3781 ctcttagggc gaggagatat gctattcttg ccaatgggtg agaataaacc gatccgtgtg
     3841 caaggagcat tcatttctga ccacgaagta gaacgggtcg ttcaatttgt tacagatcag
     3901 caagaagctc attatgaaga gaaaatgatg ccgacagatg aagttgaaac gacaggtgct
     3961 ccagaacagc cacaagatga gctgtttgaa gaagcaaaag cacttgtcgt tgaaatgcaa
     4021 acggcaagta tttcccttct ccaaagaaga tttcggatcg gttacaaccg agcagcacgt
     4081 ttagtagatg aactggaagc tcatggagtt gttggcccgt cagaaggaag caagcctcgg
     4141 aaagtattca ttgagcagga agaaacatca gaaacgttgc cggacgataa tgacatgtaa
     4201 aacttgtgtg atgaagggtt gaaaaacgaa taaccaataa aaagacaagg catgatgata
     4261 ccaaaagaaa aaatggtttt tttccatctt ttctaatacg gtatgatgtc ttgtcttttt
     4321 agtttttgtg agattaaagt tctattcgat ttatttgtga agtattgcat taaggaaatg
     4381 aatcatgtat agtatgtagc gaaactttga gaaaaagagg gaaaatactt tggaaaaaca
     4441 gtccatttat ggcttgacga atgaagaatt aatcaattgg tttatagaaa acggcgagaa
     4501 aaaattccga gctgcccaag tttgggaatg gttgtatcaa aaacgtgtaa gtaatttcac
     4561 agaaatgacg aatctatcga aacaattgat cgaaaaatta tcggagcatt ttatcatcaa
     4621 tcctctaaaa cagatggtcg tccaagaagc ttcggatggt acagtaaaat atttgtttga
     4681 actccctgat aaaaacatga ttgagactgt actgatgaga caagaatatg gcttgtcagt
     4741 ttgtgtgacg acacaagtag gatgtaatat cggctgtacg ttttgtgcaa gcgggctgct
     4801 caaaaagaac cgtgatctga ctgctggaga aattgttgca cagatcatga tggtccaaca
     4861 ttattttgat gagcgcaatc ttggcgaacg cgtttcacat gtcgttgtaa tggggatcgg
     4921 tgagccattt gataattacg acaatgtaat ggactttttg catatcatca atgatgccaa
     4981 aggattggca attggtgctc ggcacattac agtttccact agtggattag cacacaaaat
     5041 caaggaattc gctaataacg gcttgcaagt caatctggct atttccttgc acgcgccgaa
     5101 taatgaggtg cgaacatcga tcatgcggat caaccgaagt ttcccaattg agaaattgat
     5161 ggaagctgtg gatgagtatt tagagaaaac aaaccgtcga atcacgtttg aatatatcat
     5221 gttgaatcaa gtaaatgata gaccagagca tgcgcaacaa ttagcagatc tattaaaaga
     5281 taagaaaaaa ttagcatatg tcaacttgat tccatataat ccagtcagtg aacatgatca
     5341 atattctcgc agtccaaaag ctgatgtatt gagattttat gatgtattga agaaaaacgg
     5401 cgtaaactgt gtgatacgta aagaacatgg tacagatatt gatgcagctt gcggacaatt
     5461 gcgaagcaag caaatgaaaa aaacagttgc caaataatcg tatcctactc gttttttcaa
     5521 ttaccataaa aggagcagtt ttcttaatta aggaactgtt caacttaaat aagagaaaag
     5581 attctatagc gaaagctata aagctttttt tgacaagaaa aaccctcatc aagcaaagaa
     5641 atgtcctcaa tttgatgaca gcctgcttga tgggggtttt agcaattatt taactgattt
     5701 tcttatatcc ttgctggctt tcttgtgtag catgataagt ttctacgtca agaatggcct
     5761 gtttaaattt ttctcgggtg atttcataag gcacatgttt aatatcattt gttgccatgg
     5821 ctttatctaa gattgcttct aaatcggtcg tgacattgag attcatgtcg gttaacgata
     5881 ctggaagttg gttctttttc ataaacacat agattttatc aaacaaatcg aactgctgat
     5941 ccatcatcaa taaggtcagt acaccataac tgacagatgc tccgtgaagg tatccctcca
     6001 ttttttctag aacagtcgta ccgtaataga atgagtgtgc catagcagaa ttatagttat
     6061 tgttaactaa aacagaaacc aatccggtag taacaatgat atccgaaacg acttgttcaa
     6121 ttgcatatga gggacgatcg tcggcactat ctttcaatgc ttgcgtacca taagtcaaga
     6181 gacgatcaat gcacattttt ccgatttgga ttcctaatct atccgtgtag cctagatcat
     6241 cgccacgagc agaaaaagta gattcgactt ctttggataa agcatcgcca atacctgccc
     6301 ataagtattt atcaggtgct tcggcaataa ttgctgtatc aatgaaggtg tgtacaggtg
     6361 gttttgaagg aaagaagagt ccgtccatta cgccttcttc gttatagatg acacataccg
     6421 cagtgacggg cgaacagttc gaaccaatag tgggaaaggt gaagactggt ttagctagtt
     6481 tttcaccaat gacttttaca gtatcgcaag cacggccacc accgactgca aacaggacgt
     6541 ctgctttttg gacactttca tgctggatca actgttcaat atttccataa gttgaattac
     6601 ccccgtacca gagactggcg acaacctcta tttcctgtgt caaagctact tttattttgt
     6661 tttctgcctt tgaaagtgca gtcttccctc caatcagcac tacttttgtc ccatattctt
     6721 tgacgattcc atttgctttt tcatacgcat ctgttccaat ggtataattt ggtaagaaaa
     6781 cactttgact catattcatt tccttctttc ttcgttgaaa cgggttaaaa ttttaaagag
     6841 tgatcgatct gactgcggct gtagatggag tagaggtgaa cctaagacag gataagtgat
     6901 gaataaggtg gcatgaacac cttgaaatca tcaataagta tcctaaaaac gaacaagtac
     6961 aaaaacattg aaaacgacaa taatgaattt ttgttcctct tagtatttct accgattccc
     7021 tttgcttttt tgtaattatc taaaaattct aaaaattaag attattatat gaaaacaggt
     7081 tttatttgtc aattcataat tggttttttt taaagcaaaa gataatctat atcatgatga
     7141 acaaacagag ttttttcctc caattgatgg ctttcctgat ctttcctatt ttgaataaag
     7201 tgtttctgta taatttttta ttttataagt aagataaata atgaaagaat agagatactg
     7261 attggtagct aaagattttt gagcgagaac atttcgtttt ttcaaaagga ctgttagaat
     7321 aagcaagaac aagggggaag acgtatgata atcagtgaat ttgaccgtaa taatccagta
     7381 ttgaaagatc agctttctga tttactgaga ctgacttggc cggaagaata tggagacagc
     7441 tcggcagaag aagtagaaga aatgatgaat ccagaacgaa tcgcggtagc agcggtagac
     7501 caagatgagt tagtaggatt tattggtgca atccctcaat acggtatcac aggttgggaa
     7561 ttgcatccat tagttgtaga aagctcccga cgaaagaacc aaataggtac tcgattagtc
     7621 aattacttag aaaaagaagt agcttccaga ggaggaatca cgatttattt aggtacggat
     7681 gatttagacc atggaacaac gttaagtcaa acggacctgt atgagcatac atttgataaa
     7741 gtggcttcca tccagaacct tcgtgaacat ccgtatgaat tctatgaaaa attaggttat
     7801 aaaatcgtag gtgtcttacc aaatgcaaat ggctgggaca aaccggatat ttggatggca
     7861 aaaacgatta ttcctcgacc aaattctcaa taataaaaag aggttgtgac agaagtaatc
     7921 agcttcaaga aataagaagg aatttacgaa aattactt
//
LOCUS       DAFENC010000177         5851 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.guided.098, whole genome shotgun sequence.
ACCESSION   DAFENC010000177
VERSION     DAFENC010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5851
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.guided.098"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            322..1014
                     /locus_tag="LP493_003069"
     CDS             322..1014
                     /locus_tag="LP493_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBL2135132.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
     gene            1341..1838
                     /gene="dfrG"
                     /locus_tag="LP493_003070"
     CDS             1341..1838
                     /gene="dfrG"
                     /locus_tag="LP493_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HBL2135133.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(1910..3862)
                     /locus_tag="LP493_003071"
     CDS             complement(1910..3862)
                     /locus_tag="LP493_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HBL2135134.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3869..4105)
                     /locus_tag="LP493_003072"
     CDS             complement(3869..4105)
                     /locus_tag="LP493_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2135135.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            4507..4797
                     /locus_tag="LP493_003073"
     CDS             4507..4797
                     /locus_tag="LP493_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBL2135136.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            5511..5813
                     /locus_tag="LP493_003074"
                     /pseudo
     CDS             5511..5813
                     /locus_tag="LP493_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1997 a          925 c         1010 g         1919 t
ORIGIN      
        1 tttcataggt aaaagaagca tgacaattta tgacaaatcc gcgttttttg taataaatac
       61 agtaatctat gaaatgaaaa gggttacgtt taataaaact tgcttttttg tttttgttca
      121 ccataaatat ttatttaaga aagtattaac ctgcattttt ctctataaaa aagatttttt
      181 aaatagataa aaaaggagga ttaaatgagt atttgatagt atttatatta aaattacata
      241 tgtaatttaa aaacgcttga cattgtgttt gagatcactt acttttagca tgtaaaagta
      301 ttggattaag gagctatgca aatgaaaaag aaatttatta ctggtgggat tgtcgttgca
      361 tttctatgtc taattggcta cacaggcacg cggtacgcaa atgaaattat tttgtggggt
      421 ggagagacag atattgatac aatcaatgag aatctgacac agcttgatca tacattgaca
      481 gataaagagc aagcgattac agatcttacc gctcgactag cacaaaaaga acagacattg
      541 caagattcaa aggcagatgt ccaagaatac caaacaaaag taaatgaatt agaaaaccaa
      601 aaaaatcaat cggcagcaga aaaacaaaac ttagaaagtc aattagtcag caaggatgca
      661 caactacaaa gcaaacaaaa tgaaatcaat gtcaaactag atgagatcaa ccaaaaaaat
      721 gatgaaatca atcatctgaa tgcagattgg acagcaagac tacaagaagc acaagcaaaa
      781 ctttcagaat tacaaaatac tgtaaatggt ttgaatcaac aaatcgcaac actgacacaa
      841 gaaaaaacaa atgtagaaac tcagttaaca gatacacaaa agaaattaga cgaagcaact
      901 gctgaaaact caagcttgaa acaatatatt caaaagttag aaaaagcaaa agatgaagtg
      961 gaagatacag ctgataaatc tcagcaaatt gttgaagaac atttgcgtaa ataatctttc
     1021 ttaacaagta aacctaaatt agtaaagaag caacagtaat ctatactaag tagttcagtt
     1081 ttggagtaca aaatgacaaa atgtacttca aaatggacta cttttttcat tttaacttac
     1141 ataccaaatt acatacaaaa tgatttataa aatgcaattg aaaatgataa ttgaatgaaa
     1201 atttgtgatt ttgtggtatt atgataatat aacttataga aaaaattgct tattcaacta
     1261 acgggcagga taatgagaaa aggttttttg atagaaataa gaaattagat ggtaaattag
     1321 ttaaaaaggc tgtgttataa atgaaagttt ctttgattgc tgcgatggat aagaatagag
     1381 tgattggcaa agagaatgac attccttgga ggattcccaa ggactgggaa tatgttaaaa
     1441 atactacaaa gggacatccg ataatattag gtaggaagaa ccttgaatca atcggaagag
     1501 ccttacctga cagaagaaat attattctga cgagagataa ggggtttacc tttaatggtt
     1561 gtgaaattgt tcattcaata gaagatgttt ttgagttatg taaaaacgaa gaagaaattt
     1621 ttattttcgg aggagaacag atttataatt tgtttttccc ttatgttgag aaaatgtaca
     1681 tcacaaaaat acatcatgaa ttcgaaggag atactttttt tccagaagtg aattatgagg
     1741 aatggaatga ggtatttgcc caaaaaggga taaagaatga taaaaatccg tataactact
     1801 attttcatgt atatgaaaga aaaaacttat tgagttaacg ggtgcgttaa ttgaagaaga
     1861 acagtaaaga taaagcacaa gagcttggga ttactccaag ctctttttgt catttgaaat
     1921 aaattatatc tttccaatca aattgtttat ctgtaatccc taatctttga gcaggtgtca
     1981 aaaccttttt atccgctgat ttaaaagggc gacaaaagtt gtagtaagtt cttagaattg
     2041 taatcgcaaa ttgagcatac ttcggattga agttagcgta aatatagctc ttcttatcac
     2101 cacgagctgt tgttaatggt ctttcaagag atgatatata acgtcttatc tgttgaataa
     2161 agctattggt cgaatggtca ttaacattta atagcatctt tgcgatttcg tttggttcca
     2221 gagcagataa atccgttcta caatcaactg aataaaatcc tttatcctta gtggctaatg
     2281 gatgtttgat agggttatcg gcatatttgc gatatctttc tccatcttta ctaatagcct
     2341 cttcgtggaa ttgatgactt gttagtaatt cagttagata atgagatgcc aaagtccgta
     2401 gaaactttgt tttgaatcct ctgatatctc cccaatcgag cagttctgct tttgcttgtc
     2461 cgaattcttt taagcattgt tttctgcttt tcgtcttgtt aacttggcaa ataaaatgat
     2521 gtgcatcgct caaccttaat tctttcgtga atactctata aaaggcgttt ctaatagaga
     2581 agtcatcatc actaatcatt cgccattcgt cggcattaac catttgttta attaaccaat
     2641 agtgagcagt tgtagtataa ggagcatcaa catttaaacc atcgacaaat ctactcctat
     2701 tagtaatttt ccctaattcg tgaagataag cattcctatt ttcgctatcg ttagcggatg
     2761 gttcttgtgg ataataagac caatctaacc tatcattttt acgactaaaa gtattgagat
     2821 ggtcttcttt gaattttctt gtatcttcat ttaattcatc cattgaaata ttccaatcat
     2881 aggcaacatc agaacggaac acatatcttg ataagacctc agcagataca actatatacg
     2941 tttgcatatt aaggtcttca aaccccgtat atttctttga accttgtcct ttcttacgga
     3001 cgttatttag gtagtagtgc atcttgtccg tattaagcca catctcgtta aatttctttg
     3061 tttgaagggg ttgtgtctca tatcgttcta aaaactccaa acaacgccta tacagccact
     3121 ccagcttatg atagtaggtt ccaactccaa ttcctaaaat atcacaagta cgactgactg
     3181 aaacccttcc aacaaccatc ttagcgaaca ttggaagaat ggtgttcttt tgttggtgat
     3241 aagtagtggt ttcttctctt tttggtagaa cattagtgaa cttcttacac gccttacatt
     3301 gatagcgttg agatttgccc ctacttttcc cccttttgta aaattgcttc ggctcattga
     3361 atggggttga ttcttcttcc gagcagcctt ctttatgaaa ttgataatct ggctcaacat
     3421 cttggatgct attgatttct ataaggcgtt taatttcttc aacaacagac caattagata
     3481 aaggggttac tgtacagttt tgcgatacac ctctgccaat aggattgtca ttgcagtaca
     3541 tacctttatg acctttatct ttggaactac cagtcatttt atatcgactt ggtttccctt
     3601 ttacatcttt gaatttgtgc tgttctttcc caaaattaca acaaaacgga ttgatgcagt
     3661 aattatattg aatgggatat tcagaaccgt tccatttaaa agacgttggc aagaacaaca
     3721 ttttgttata ccttgttgca aatcgttttg gagttaataa atcatattgt ttagccctat
     3781 cttttaattc ttcgtttgaa atcggaattt taacatctac aatttcatct tccttcgtgg
     3841 ctaatctttt aagcttggtc attgtctatc aacccactct atctttgata cccatttttt
     3901 caacaatccg cttattactt cgcttgttgg caatccattc aataaacttc ttatcgtcta
     3961 aaatgttcaa taagaattca tccactgctt cgctttcagt acgctctgca tattcagcgt
     4021 attgcttaac tatcaccctt acttgctctg atatttccca atccacagac ttagcgttct
     4081 tattttttgg ctcaagaaat tgcataggaa aatgcacccc tttttgctta gtaaattgta
     4141 accattttaa cacaccaatt tgcattccta caataattat ttcacgttcg catttttata
     4201 tacattttaa cttacatttt gtggtgtaaa ttaacaacaa acgttgattt aacaataaaa
     4261 aacgagtatc aaattcagtt gcaatttgat actcatttag gtttacattt tcactttttg
     4321 tactccaaaa ctgaactact taaatctata ctgctgcctc ttttttttag tacatgtcct
     4381 tcatcttcgc aggaagtgcc aatatgattt taagaaaggt aatagacaaa aagtcaaaaa
     4441 gataaaacag agtttcttct ttacaaaggg aatgtatgtt cgtataatgg tattgaggtg
     4501 aaggttatgg agaaaaaata tggaacagta gataagatcc gtactttgca agttagtgcc
     4561 agaccgttga tccgtttcag tttaaatggg gtcaattgtt tgattgcttc ccatagtttg
     4621 aacttcctag ctgaagtaga cgaagggatg aagttagtcg ttacaggtta ttataataat
     4681 agaaagcaat ttgttgtgag atcctatcat gtgttaggga aacccaaaat tgtggtagaa
     4741 tatgagaaaa gtctataccc aagaaaaaag gtccgacaag atgaaagaat aaactagaaa
     4801 acaagcggct gagacaaaaa tgtcctagcc gcttgttttg gaaagatgga tgcagacgat
     4861 gggatttgaa cccacacgag catacgctca caagaacctc aatctatata taactacatg
     4921 tatttaagta tttgtgatga atcactaaac tttccaaact catttgaggg atattgctta
     4981 aagattgaac agatcaattc gaagccctat tagtattcgc tcaatggggg gatcagaggc
     5041 cataaaaaga gactagtcat tactagtctc aggtagtgga attgtaggat tttaaacgtt
     5101 cctggagagt accggtatgt aactcgaaga ggtgattatc atagtcgtaa aagtaaattg
     5161 aagaagcctc gcctttcaca cgagaacgtc ctggttcgac agttaaacct aacatttgga
     5221 tttttgagac aaacgaatct atatcttgtt cgtcaatttt aaaagcaata tgattgtatg
     5281 tctttggcag tttattcgac gaattctgca ttactgcaat ccataggtcc ttaactaaga
     5341 aaaatttttc tggatataat gaaaattttt ttgttgacta tcgtagattt cttttgcatc
     5401 aaataaggta tttaacaatt aagtatttaa aagataactt ttaagttatc tttaagtaat
     5461 gcttaaagct atgttatact ctattaggaa atataagaag gagtataaaa atgaacaaac
     5521 ataatagaaa aataacgaat aacaaagaac tgatcttgtt actaataggg atttggggta
     5581 tctttttact ctttaatatg tatatgccga ctatgagagc ggatgacgta gtttatgcaa
     5641 gtagattaga tgaacttggc tatttgggtg cttcgataga acattataag acatggagtt
     5701 caagaattat tatagaacta ttcttaatgt tcttttctaa acactttatg ctatggaaat
     5761 tattaaattc tacgattatg ttaggaattg tagtattact ttgcaagtat gttgagagta
     5821 taaaatattt tgtgtaaatg aaaaaatcca t
//
LOCUS       DAFENC010000178         3286 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.guided.119, whole genome shotgun sequence.
ACCESSION   DAFENC010000178
VERSION     DAFENC010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3286
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.guided.119"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            246..1214
                     /locus_tag="LP493_003075"
     CDS             246..1214
                     /locus_tag="LP493_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HBL2135137.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1207..2238
                     /gene="vanA"
                     /locus_tag="LP493_003076"
     CDS             1207..2238
                     /gene="vanA"
                     /locus_tag="LP493_003076"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HBL2135138.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2244..2852
                     /locus_tag="LP493_003077"
     CDS             2244..2852
                     /locus_tag="LP493_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HBL2135139.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT          984 a          626 c          795 g          881 t
ORIGIN      
        1 gatgctggtg tcatccacca acatcaaaaa gtatagagcc ataatttttt aggaaaatct
       61 caaggttatc tttacttttt cttaggaaat taacaattta atattaagaa acggctcgtt
      121 cttacacggt agacttaata ccgtaagaac gagccgtttt cgttcttcag agaaagattt
      181 gacaagatta ccattggcat ccccgtttta tttggtgcct ttcacagaaa gggttggtct
      241 taattatgaa taacatcggc attactgttt atggatgtga gcaggatgag gcagatgcat
      301 tccatgctct ttcgcctcgc tttggcgtta tggcaacgat aattaacgcc aacgtgtcgg
      361 aatccaacgc caaatccgcg cctttcaatc aatgtatcag tgtgggacat aaatcagaga
      421 tttccgcctc tattcttctt gcgctgaaga gagccggtgt gaaatatatt tctacccgaa
      481 gcatcggctg caatcatata gatacaactg ctgctaagag aatgggcatc actgtcgaca
      541 atgtggcgta ctcgccggat agcgttgccg attatactat gatgctaatt cttatggcag
      601 tacgcaacgt aaaatcgatt gtgcgctctg tggaaaaaca tgatttcagg ttggacagcg
      661 accgtggcaa ggtactcagc gacatgacag ttggtgtggt gggaacgggc cagataggca
      721 aagcggttat tgagcggctg cgaggatttg gatgtaaagt gttggcttat agtcgcagcc
      781 gaagtataga ggtaaactat gtaccgtttg atgagttgct gcaaaatagc gatatcgtta
      841 cgcttcatgt gccgctcaat acggatacgc actatattat cagccacgaa caaatacaga
      901 gaatgaagca aggagcattt cttatcaata ctgggcgcgg tccacttgta gatacctatg
      961 agttggttaa agcattagaa aacgggaaac tgggcggtgc cgcattggat gtattggaag
     1021 gagaggaaga gtttttctac tctgattgca cccaaaaacc aattgataat caatttttac
     1081 ttaaacttca aagaatgcct aacgtgataa tcacaccgca tacggcctat tataccgagc
     1141 aagcgttgcg tgataccgtt gaaaaaacca ttaaaaactg tttggatttt gaaaggagac
     1201 aggagcatga atagaataaa agttgcaata ctgtttgggg gttgctcaga ggagcatgac
     1261 gtatcggtaa aatctgcaat agagatagcc gctaacatta ataaagaaaa atacgagccg
     1321 ttatacattg gaattacgaa atctggtgta tggaaaatgt gcgaaaaacc ttgcgcggaa
     1381 tgggaaaacg acaattgcta ttcagctgta ctctcgccgg ataaaaaaat gcacggatta
     1441 cttgttaaaa agaaccatga atatgaaatc aaccatgttg atgtagcatt ttcagctttg
     1501 catggcaagt caggtgaaga tggatccata caaggtctgt ttgaattgtc cggtatccct
     1561 tttgtaggct gcgatattca aagctcagca atttgtatgg acaaatcgtt gacatacatc
     1621 gttgcgaaaa atgctgggat agctactccc gccttttggg ttattaataa agatgatagg
     1681 ccggtggcag ctacgtttac ctatcctgtt tttgttaagc cggcgcgttc aggctcatcc
     1741 ttcggtgtga aaaaagtcaa tagcgcggac gaattggact acgcaattga atcggcaaga
     1801 caatatgaca gcaaaatctt aattgagcag gctgtttcgg gctgtgaggt cggttgtgcg
     1861 gtattgggaa acagtgccgc gttagctgtt ggcgaggtgg accaaatcag gctgcagtac
     1921 ggaatctttc gtattcatca ggaagtcgag ccggaaaaag gctctgaaaa cgcagttata
     1981 accgttcccg cagacctttc agcagaggag cgaggacgga tacaggaaac ggcaaaaaaa
     2041 atatataaag cgctcggctg tagaggtcta gcccgtgtgg atatgttttt acaagataac
     2101 ggccgcattg tactgaacga agtcaatact ctgcccggtt tcacgtcata cagtcgttat
     2161 ccccgtatga tggccgctgc aggtattgca cttcccgaac tgattgaccg cttgatcgta
     2221 ttagcgttaa aggggtgata agcatggaaa taggatttac ttttttagat gaaatagtac
     2281 acggtgttcg ttgggacgct aaatatgcca cttgggataa tttcaccgga aaaccggttg
     2341 acggttatga agtaaatcgc attgtaggga catacgagtt ggctgaatcg cttttgaagg
     2401 caaaagaact ggctgctacc caagggtacg gattgcttct atgggacggt taccgtccta
     2461 atcgtgctgt aaactgtttt atgcaatggg ctgcacagcc ggaaaataac ctgacaaagg
     2521 aaagttatta tcccaatatt gaccgaactg agatgatttc aaaaggatac gtggcttcaa
     2581 aatcaagcca tagccgcggc agtgccattg atcttacgct ttatcgatta gacacgggtg
     2641 agcttgtacc aatggggagc cgatttgatt ttatggatga acgctctcat catgcggcaa
     2701 atggaatatc atgcaatgaa gcgcaaaatc gcagacgttt gcgctccatc atggaaaaca
     2761 gtgggtttga agcatatagc ctcgaatggt ggcactatgt attaagagac gaaccatacc
     2821 ccaatagcta ttttgatttc cccgttaaat aaacttttaa ccgttgcacg gacaaactat
     2881 ataagctaac tctttcggca ggaaacccga cgtatgtaac tggttcttag ggaatttata
     2941 tatagtagat agtattgaag atgtaaggca gagcgatatt gcggtcatta tctgcgtgcg
     3001 ctgcggcaag atagcctgat aataagactg atcgcataga ggggtggtat ttcacaccgc
     3061 ccattgtcaa caggcagttc agcctcgtta aattcagcat gggtatcact tatgaaaatt
     3121 catctacatt ggtgataata gtaaatccag tagggcgaaa taattgactg taatttacgg
     3181 ggcaaaacgg cacaatctca aacgagattg tgccgtttaa ggggaagatt ctagaaatat
     3241 ttcatacttc caactatata gttaaggagg agactgaaaa tgaaga
//
LOCUS       DAFENC010000179         1872 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.guided.136, whole genome shotgun sequence.
ACCESSION   DAFENC010000179
VERSION     DAFENC010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1872
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.guided.136"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            34..945
                     /gene="vanY"
                     /locus_tag="LP493_003078"
     CDS             34..945
                     /gene="vanY"
                     /locus_tag="LP493_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HBL2135140.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            1098..1583
                     /gene="vanZ"
                     /locus_tag="LP493_003079"
     CDS             1098..1583
                     /gene="vanZ"
                     /locus_tag="LP493_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HBL2135141.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
BASE COUNT          660 a          260 c          355 g          597 t
ORIGIN      
        1 cttccaacta tatagttaag gaggagactg aaaatgaaga agttgttttt tttattgtta
       61 ttgttattct taatatactt aggttatgac tacgttaatg aagcactgtt ttctcaggaa
      121 aaagtcgaat ttcaaaatta tgatcaaaat cccaaagaac atttagaaaa tagtgggact
      181 tctgaaaata cccaagagaa aacaattaca gaagaacagg tttatcaagg aaatctgcta
      241 ttaatcaata gtaaatatcc tgttcgccaa gaaagtgtga agtcagatat cgtgaattta
      301 tctaaacatg acgaattaat aaatggatac gggttgcttg atagtaatat ttatatgtca
      361 aaagaaatag cacaaaaatt ttcagagatg gtcaatgatg ctgtaaaggg tggcgttagt
      421 cattttatta ttaatagtgg ctatcgagac tttgatgagc aaagtgtgct ttaccaagaa
      481 atgggggctg agtatgcctt accagcaggt tatagtgagc ataattcagg tttatcacta
      541 gatgtaggat caagcttgac gaaaatggaa cgagcccctg aaggaaagtg gatagaagaa
      601 aatgcttgga aatacgggtt cattttacgt tatccagagg acaaaacaga gttaacagga
      661 attcaatatg aactatggca tattcgctat gttggtttac cacatagtgc gattatgaaa
      721 gaaaagaatt tcgttctcga ggaatatatg gattacctaa aagaagaaaa aaccatttct
      781 gttagtgtaa atggggaaaa atatgagatc ttttattatc ctgttactaa aaataccacc
      841 attcatgtgc cgactaatct tcgttatgag atatcaggaa acaatataga cggtgtaatt
      901 gtgacagtgt ttcccggatc aacacatact aattcaagga ggtaaggatg gcggaatgaa
      961 accaacgaaa ttaatgaaca gcattattgt actagcactt ttggggtaac gttagctttt
     1021 taatttaaaa cccacgttaa ctaggacatt gctatactaa tgatacaact taaacaaaag
     1081 aattagagga aattatattg ggaaaaatat tatctagagg attgctagct ttatatttag
     1141 tgacactaat ctggttagtg ttattcaaat tacaatacaa tattttatca gtatttaatt
     1201 atcatcaaag aagtcttaac ttgactccat ttactgctac tgggaatttc agagagatga
     1261 tagataatgt tataatcttt attccatttg gcttgctttt gaatgtcaat tttaaagaaa
     1321 tcggattttt acctaagttt gcttttgtac tggttttaag tcttactttt gaaataattc
     1381 aatttatctt cgctattgga gcgacagaca taacagatgt aattacaaat actgttggag
     1441 gctttcttgg actgaaatta tatggtttaa gcaataagca tatgaatcaa aaaaaattag
     1501 acagagttat tatttttgta ggtatacttt tgctcgtatt attgctcgtt taccgtaccc
     1561 atttaagaat aaattacgtg taagatgtct aaatcaagca atctgatctt tcatacacat
     1621 aaagatattg aatgaattgg attagatgga aaacgggatg tggggaaact cgcccgtagg
     1681 tgtgaagtga ggggaaaacc ggtgataaag taaaaagctt acctaacact atagtaacaa
     1741 agaaagccca attatcaatt ttagtgctga ggaattggtc tctttaataa atttccttaa
     1801 cgttgtaaat ccgcattttc ctgacggtac ccccaaacta agatttcata gatagatttt
     1861 ctgataactt ta
//
LOCUS       DAFENC010000180         1872 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.guided.137, whole genome shotgun sequence.
ACCESSION   DAFENC010000180
VERSION     DAFENC010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1872
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.guided.137"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            34..945
                     /gene="vanY"
                     /locus_tag="LP493_003080"
     CDS             34..945
                     /gene="vanY"
                     /locus_tag="LP493_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HBL2135142.1"
                     /translation="MKTLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            1098..1583
                     /gene="vanZ"
                     /locus_tag="LP493_003081"
     CDS             1098..1583
                     /gene="vanZ"
                     /locus_tag="LP493_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HBL2135143.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
BASE COUNT          659 a          261 c          355 g          597 t
ORIGIN      
        1 cttccaacta tatagttaag gaggagactg aaaatgaaga cgttgttttt tttattgtta
       61 ttgttattct taatatactt aggttatgac tacgttaatg aagcactgtt ttctcaggaa
      121 aaagtcgaat ttcaaaatta tgatcaaaat cccaaagaac atttagaaaa tagtgggact
      181 tctgaaaata cccaagagaa aacaattaca gaagaacagg tttatcaagg aaatctgcta
      241 ttaatcaata gtaaatatcc tgttcgccaa gaaagtgtga agtcagatat cgtgaattta
      301 tctaaacatg acgaattaat aaatggatac gggttgcttg atagtaatat ttatatgtca
      361 aaagaaatag cacaaaaatt ttcagagatg gtcaatgatg ctgtaaaggg tggcgttagt
      421 cattttatta ttaatagtgg ctatcgagac tttgatgagc aaagtgtgct ttaccaagaa
      481 atgggggctg agtatgcctt accagcaggt tatagtgagc ataattcagg tttatcacta
      541 gatgtaggat caagcttgac gaaaatggaa cgagcccctg aaggaaagtg gatagaagaa
      601 aatgcttgga aatacgggtt cattttacgt tatccagagg acaaaacaga gttaacagga
      661 attcaatatg aactatggca tattcgctat gttggtttac cacatagtgc gattatgaaa
      721 gaaaagaatt tcgttctcga ggaatatatg gattacctaa aagaagaaaa aaccatttct
      781 gttagtgtaa atggggaaaa atatgagatc ttttattatc ctgttactaa aaataccacc
      841 attcatgtgc cgactaatct tcgttatgag atatcaggaa acaatataga cggtgtaatt
      901 gtgacagtgt ttcccggatc aacacatact aattcaagga ggtaaggatg gcggaatgaa
      961 accaacgaaa ttaatgaaca gcattattgt actagcactt ttggggtaac gttagctttt
     1021 taatttaaaa cccacgttaa ctaggacatt gctatactaa tgatacaact taaacaaaag
     1081 aattagagga aattatattg ggaaaaatat tatctagagg attgctagct ttatatttag
     1141 tgacactaat ctggttagtg ttattcaaat tacaatacaa tattttatca gtatttaatt
     1201 atcatcaaag aagtcttaac ttgactccat ttactgctac tgggaatttc agagagatga
     1261 tagataatgt tataatcttt attccatttg gcttgctttt gaatgtcaat tttaaagaaa
     1321 tcggattttt acctaagttt gcttttgtac tggttttaag tcttactttt gaaataattc
     1381 aatttatctt cgctattgga gcgacagaca taacagatgt aattacaaat actgttggag
     1441 gctttcttgg actgaaatta tatggtttaa gcaataagca tatgaatcaa aaaaaattag
     1501 acagagttat tatttttgta ggtatacttt tgctcgtatt attgctcgtt taccgtaccc
     1561 atttaagaat aaattacgtg taagatgtct aaatcaagca atctgatctt tcatacacat
     1621 aaagatattg aatgaattgg attagatgga aaacgggatg tggggaaact cgcccgtagg
     1681 tgtgaagtga ggggaaaacc ggtgataaag taaaaagctt acctaacact atagtaacaa
     1741 agaaagccca attatcaatt ttagtgctga ggaattggtc tctttaataa atttccttaa
     1801 cgttgtaaat ccgcattttc ctgacggtac ccccaaacta agatttcata gatagatttt
     1861 ctgataactt ta
//
LOCUS       DAFENC010000181         1763 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.guided.138, whole genome shotgun sequence.
ACCESSION   DAFENC010000181
VERSION     DAFENC010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1763
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.guided.138"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            56..790
                     /locus_tag="LP493_003082"
     CDS             56..790
                     /locus_tag="LP493_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL2135144.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            823..1738
                     /gene="ant(6)"
                     /locus_tag="LP493_003083"
                     /pseudo
     CDS             823..1738
                     /gene="ant(6)"
                     /locus_tag="LP493_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
BASE COUNT          614 a          245 c          404 g          500 t
ORIGIN      
        1 gaagtgaatg aaattgtatc ggagataaat aactttttaa acgaggagag ttcagatgaa
       61 agaaaacaaa tatgatgata atatattttt tcaaaaatac agtcaaatga gtcgctcgca
      121 gaaaggactg gctggtgcgg gagaatggga gactttgaaa aagatgctac ctgattttaa
      181 gggtaagcgt gtgcttgatt taggatgcgg ctatggatgg cactgtatat atgcgatgga
      241 aaacggtgct tcctctgtag taggtgttga tatttctcat aaaatgctcg aagtagcaaa
      301 aggaaaaacc cattttccac agattgaata tgaatgctgt gccatagaag atgtggattt
      361 cccagaggag agctttgatg taatactaag ttcgcttgcg tttcattatg tagcagacta
      421 tgagaattta ataaaaaaga tatataggat gctgaaggct ggtggcaatt tagtttttac
      481 agttgaacat cctgttttta ctgctcatgg aacacaagac tggtattata acgaaaaagg
      541 agaaatactg catttcccgg tggacaatta ttattatgag ggcaaacgga cagctatgtt
      601 tttggaagaa aaggttacaa aatatcatag aacactgacc acatatctaa atacactgct
      661 ttcaaatagt tttataataa atcagattgt ggagccacag ccgccagaga acatgatgga
      721 tattccgggg atggcggatg aaatgcgacg cccaatgatg ctgattgtat cggcaaaaaa
      781 gaagatgtaa taatatagaa aaaataaacg aggagtatgt aaatgagatc agaaaaagaa
      841 atgatggatt tagtactttc tttagcagaa caggatgaac gtattcgaat tgtgaccctt
      901 gaggggtcac gcgcaaatat taatatacct aaagatgaat ttcaggatta tgatattaca
      961 tattttgtaa gtgatataga acctagaacc gtttatatct aatgatgact ggcttaatca
     1021 atttgggaat ataataatga tgcaaaagcc ggaggatatg gaattattcc cacctgaaga
     1081 aaagggattt tcctatctta tgctatttga tgattacaat aaaattgatc ttaccttatt
     1141 gcccttggaa gagttagata attacctaaa gggcgataaa ttaataaagg ttctaattga
     1201 taaagattgt agaattaaaa gggacatagt tccgactgat atagattatc atgtaagaaa
     1261 gccaagcgca agggagtatg atgattgctg caatgaattt tggaatgtaa caccttatgt
     1321 tattaaagga ttgtgccgta aggaaatttt atttgctatt gatcatttta atcagattgt
     1381 tcgccatgag ctgctgagaa tgatatcatg gaaggtcggc atcgaaacag gctttaaatt
     1441 aagtgtaggc aagaactata agtttattga aaggtatata tccgaggatt tgtgggagaa
     1501 acttttgtcc acctaccgga tggattccta tgaaaacata tgggaagcat tatttctatg
     1561 ccatcaattg ttcagggcgg tatccggtga ggtggcggaa aggcttcatt atgcctatcc
     1621 ggagtatgat aggaatataa caaaatatac cagggacatg tataaaaaat acactggtaa
     1681 aaccggctgc ctggatagca catatgccgc tgatatagaa gagaggcggg aacagtgatt
     1741 acagaaatga aagcagggca cct
//
LOCUS       DAFENC010000182         1756 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.guided.139, whole genome shotgun sequence.
ACCESSION   DAFENC010000182
VERSION     DAFENC010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1756
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.guided.139"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            56..790
                     /locus_tag="LP493_003084"
     CDS             56..790
                     /locus_tag="LP493_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBL2135145.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            823..1731
                     /locus_tag="LP493_003085"
     CDS             823..1731
                     /locus_tag="LP493_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HBL2135146.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
BASE COUNT          611 a          243 c          403 g          499 t
ORIGIN      
        1 gaagtgaatg aaattgtatc ggagataaat aactttttaa acgaggagag ttcagatgaa
       61 agaaaacaaa tatgatgata atatattttt tcaaaaatac agtcaaatga gtcgctcgca
      121 gaaaggactg gctggtgcgg gagaatggga gactttgaaa aagatgctac ctgattttaa
      181 gggtaagcgt gtgcttgatt taggatgcgg ctatggatgg cactgtatat atgcgatgga
      241 aaacggtgct tcctctgtag taggtgttga tatttctcat aaaatgctcg aagtagcaaa
      301 aggaaaaacc cattttccac agattgaata tgaatgctgt gccatagaag atgtggattt
      361 cccagaggag agctttgatg taatactaag ttcgcttgcg tttcattatg tagcagacta
      421 tgagaattta ataaaaaaga tatataggat gctgaaggct ggtggcaatt tagtttttac
      481 agttgaacat cctgttttta ctgctcatgg aacacaagac tggtattata acgaaaaagg
      541 agaaatactg catttcccgg tggacaatta ttattatgag ggcaaacgga cagctatgtt
      601 tttggaagaa aaggttacaa aatatcatag aacactgacc acatatctaa atacactgct
      661 ttcaaatagt tttataataa atcagattgt ggagccacag ccgccagaga acatgatgga
      721 tattccgggg atggcggatg aaatgcgacg cccaatgatg ctgattgtat cggcaaaaaa
      781 gaagatgtaa taatatagaa aaaataaacg aggagtatgt aaatgagatc agaaaaagaa
      841 atgatggatt tagtactttc tttagcagaa caggatgaac gtattcgaat tgtgaccctt
      901 gaggggtcac gcgcaaatat taatatacct aaagatgaat ttcaggatta tgatattaca
      961 tattttgtaa gtgatataga accgtttata tctaatgatg actggcttaa tcaatttggg
     1021 aatataataa tgatgcaaaa gccggaggat atggaattat tcccacctga agaaaaggga
     1081 ttttcctatc ttatgctatt tgatgattac aataaaattg atcttacctt attgcccttg
     1141 gaagagttag ataattacct aaagggcgat aaattaataa aggttctaat tgataaagat
     1201 tgtagaatta aaagggacat agttccgact gatatagatt atcatgtaag aaagccaagc
     1261 gcaagggagt atgatgattg ctgcaatgaa ttttggaatg taacacctta tgttattaaa
     1321 ggattgtgcc gtaaggaaat tttatttgct attgatcatt ttaatcagat tgttcgccat
     1381 gagctgctga gaatgatatc atggaaggtc ggcatcgaaa caggctttaa attaagtgta
     1441 ggcaagaact ataagtttat tgaaaggtat atatccgagg atttgtggga gaaacttttg
     1501 tccacctacc ggatggattc ctatgaaaac atatgggaag cattatttct atgccatcaa
     1561 ttgttcaggg cggtatccgg tgaggtggcg gaaaggcttc attatgccta tccggagtat
     1621 gataggaata taacaaaata taccagggac atgtataaaa aatacactgg taaaaccggc
     1681 tgcctggata gcacatatgc cgctgatata gaagagaggc gggaacagtg attacagaaa
     1741 tgaaagcagg gcacct
//
LOCUS       DAFENC010000183         1504 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.guided.144, whole genome shotgun sequence.
ACCESSION   DAFENC010000183
VERSION     DAFENC010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1504
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.guided.144"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            12..554
                     /gene="sat4"
                     /locus_tag="LP493_003086"
     CDS             12..554
                     /gene="sat4"
                     /locus_tag="LP493_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HBL2135147.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            647..1441
                     /locus_tag="LP493_003087"
                     /note="aph(3')-IIIa"
     CDS             647..1441
                     /locus_tag="LP493_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HBL2135148.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT          500 a          249 c          367 g          388 t
ORIGIN      
        1 aggcgggaac agtgattaca gaaatgaaag cagggcacct gaaagatatc gataaaccca
       61 gcgaaccatt tgaggtgata ggtaagatta taccgaggta tgaaaacgag aattggacct
      121 ttacagaatt actctatgaa gcgccatatt taaaaagcta ccaagacgaa gaggatgaag
      181 aggatgagga ggcagattgc cttgaatata ttgacaatac tgataagata atatatcttt
      241 actaccaaga cgataaatgc gtcggaaaag ttaaactgcg aaaaaattgg aaccggtacg
      301 cttatataga agatatcgcc gtatgtaagg atttcagggg gcaaggcata ggcagcgcgc
      361 ttatcaatat atctatagaa tgggcaaagc ataaaaactt gcatggacta atgcttgaaa
      421 cccaggacaa taaccttata gcttgtaaat tctatcataa ttgtggtttc aaaatcggct
      481 ccgtcgatac tatgttatac gccaactttg aaaacaactt tgaaaaagct gttttctggt
      541 atttaaggtt ttagaatgca aggaacagtg aattggagtt cgtcttgtta taattagctt
      601 cttggggtat ctttaaatac tgtagaaaag aggaaggaaa taataaatgg ctaaaatgag
      661 aatatcaccg gaattgaaaa aactgatcga aaaataccgc tgcgtaaaag atacggaagg
      721 aatgtctcct gctaaggtat ataagctggt gggagaaaat gaaaacctat atttaaaaat
      781 gacggacagc cggtataaag ggaccaccta tgatgtggaa cgggaaaagg acatgatgct
      841 atggctggaa ggaaagctgc ctgttccaaa ggtcctgcac tttgaacggc atgatggctg
      901 gagcaatctg ctcatgagtg aggccgatgg cgtcctttgc tcggaagagt atgaagatga
      961 acaaagccct gaaaagatta tcgagctgta tgcggagtgc atcaggctct ttcactccat
     1021 cgacatatcg gattgtccct atacgaatag cttagacagc cgattagccg aattggatta
     1081 cttactgaat aacgatctgg ccgatgtgga ttgcgaaaac tgggaagaag acactccatt
     1141 taaagatccg cgcgagctgt atgatttttt aaagacggaa aagcccgaag aggaacttgt
     1201 cttttcccac ggcgacctgg gagacagcaa catctttgtg aaagatggca aagtaagtgg
     1261 ctttattgat cttgggagaa gcggcagggc ggacaagtgg tatgacattg ccttctgcgt
     1321 ccggtcgatc agggaggata tcggggaaga acagtatgtc gagctatttt ttgacttact
     1381 ggggatcaag cctgattggg agaaaataaa atattatatt ttactggatg aattgtttta
     1441 gtacctagat ttagatgtct aaaaagcttt aactacaagc tttttagaca tctaatcttt
     1501 tctg
//
LOCUS       DAFENC010000184         1504 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.guided.145, whole genome shotgun sequence.
ACCESSION   DAFENC010000184
VERSION     DAFENC010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1504
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.guided.145"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            12..554
                     /gene="sat4"
                     /locus_tag="LP493_003088"
     CDS             12..554
                     /gene="sat4"
                     /locus_tag="LP493_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HBL2135149.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            647..1441
                     /locus_tag="LP493_003089"
                     /note="aph(3')-IIIa"
     CDS             647..1441
                     /locus_tag="LP493_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HBL2135150.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT          499 a          250 c          367 g          388 t
ORIGIN      
        1 aggcgggaac agtgattaca gaaatgaaag cagggcacct gaaagatatc gataaaccca
       61 gcgaaccatt tgaggtgata ggtaagatta taccgaggta tgaaaacgag aattggacct
      121 ttacagaatt actctatgaa gcgccatatt taaaaagcta ccaagacgaa gaggatgaag
      181 aggatgagga ggcagattgc cttgaatata ttgacaatac tgataagata atatatcttt
      241 actaccaaga cgataaatgc gtcggaaaag ttaaactgcg aaaaaattgg aaccggtacg
      301 cttatataga agatatcgcc gtatgtaagg atttcagggg gcaaggcata ggcagcgcgc
      361 ttatcaatat atctatagaa tgggcaaagc ataaaaactt gcatggacta atgcttgaaa
      421 cccaggacaa taaccttata gcttgtaaat tctatcataa ttgtggtttc aaaatcggct
      481 ccgtcgatac tatgttatac gccaactttg aaaacaactt tgaaaaagct gttttctggt
      541 atttaaggtt ttagaatgca aggaacagtg aattggagtt cgtcttgtta taattagctt
      601 cttggggtat ctttaaatac tgtagaaaag aggaaggaaa taataaatgg ctaaaatgag
      661 aatatcaccg gaattgaaaa aactgatcga aaaataccgc tgcgtaaaag atacggaagg
      721 aatgtctcct gctaaggtat ataagctggt gggagaaaat gaaaacctat atttaaaaat
      781 gacggacagc cggtataaag ggaccaccta tgatgtggaa cgggaaaagg acatgatgct
      841 atggctggaa ggaaagctgc ctgttccaaa ggtcctgcac tttgaacggc atgatggctg
      901 gagcaatctg ctcatgagtg aggccgatgg cgtcctttgc tcggaagagt atgaagatga
      961 acaaagccct gaaaagatta tcgagctgta tgcggagtgc atcaggctct ttcactccat
     1021 cgacatatcg gattgtccct atacgaatag cttagacagc cgcttagccg aattggatta
     1081 cttactgaat aacgatctgg ccgatgtgga ttgcgaaaac tgggaagaag acactccatt
     1141 taaagatccg cgcgagctgt atgatttttt aaagacggaa aagcccgaag aggaacttgt
     1201 cttttcccac ggcgacctgg gagacagcaa catctttgtg aaagatggca aagtaagtgg
     1261 ctttattgat cttgggagaa gcggcagggc ggacaagtgg tatgacattg ccttctgcgt
     1321 ccggtcgatc agggaggata tcggggaaga acagtatgtc gagctatttt ttgacttact
     1381 ggggatcaag cctgattggg agaaaataaa atattatatt ttactggatg aattgtttta
     1441 gtacctagat ttagatgtct aaaaagcttt aactacaagc tttttagaca tctaatcttt
     1501 tctg
//
LOCUS       DAFENC010000185         1372 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.guided.148, whole genome shotgun sequence.
ACCESSION   DAFENC010000185
VERSION     DAFENC010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1372
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.guided.148"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            266..1141
                     /locus_tag="LP493_003090"
                     /note="aph(2'')-Ia"
     CDS             266..1141
                     /locus_tag="LP493_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021424053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HBL2135151.1"
                     /translation="MKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTN
                     KKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTM
                     SEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEK
                     DYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDF
                     IYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEF
                     IENGRKEIYKRTYKD"
BASE COUNT          577 a          117 c          219 g          459 t
ORIGIN      
        1 gggattttat tctttattta aaactttgca acagaaccgt acaagatata ttaaattgat
       61 ttttgaattt ttgaaaaaag aaagaaatgc taatgcagtt attttagacc ctcataaaaa
      121 taatccaaga gcaataaggg cataccaaaa atctggtttt agaattattg aagatttgcc
      181 agaacatgaa ttacacgagg gcaaaaaaga agattgttat ttaatggaat atagatatga
      241 tgataatgcc acaaatgtta aggcaatgaa atatttaatt gagcattact ttgataattt
      301 caaagtagat agtattgaaa taatcggtag tggttatgat agtgtggcat atttagttaa
      361 taatgaatac atttttaaaa caaaatttag tactaataag aaaaaaggtt atgcaaaaga
      421 aaaagcaata tataattttt taaatacaaa tttagaaact aatgtaaaaa ttcctaatat
      481 tgaatattcg tatattagtg atgaattatc tatactaggt tataaagaaa ttaaaggaac
      541 ttttttaaca ccagaaattt attctactat gtcagaagaa gaacaaaatt tgttaaaacg
      601 agatattgcc agttttttaa gacaaatgca cggtttagat tatacagata ttagtgaatg
      661 tactattgat aataaacaaa atgtattaga agagtatata ttgttgcgtg aaactattta
      721 taatgattta actgatatag aaaaagatta tatagaaagt tttatggaaa gactaaatgc
      781 aacaacagtt tttgagggta aaaagtgttt atgccataat gattttagtt gtaatcatct
      841 attgttagat ggcaataata gattaactgg aataattgat tttggagatt ctggaattat
      901 agatgaatat tgtgatttta tatacttact tgaagatagt gaagaagaaa taggaacaaa
      961 ttttggagaa gatatattaa gaatgtatgg aaatatagat attgagaaag caaaagaata
     1021 tcaagatata gttgaagaat attatcctat tgaaactatt gtttatggaa ttaaaaatat
     1081 taaacaggaa tttatcgaaa atggtagaaa agaaatttat aaaaggactt ataaagattg
     1141 attatataat atatgaaaag ctattataaa agacattagt attaaatagt ttaaaaaaat
     1201 gaaaaataat aaaggaagtg agtcaattcc agactcctgt gtaaaatgct atacaatgtt
     1261 tttaccattt ctacttatca aaattgatgt attttcttga agaataaatc cattcatcat
     1321 gtaggtccat aagaacggtt ctgttgcaaa gttttaaatc tactatcaaa ta
//
LOCUS       DAFENC010000186         1236 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.guided.155, whole genome shotgun sequence.
ACCESSION   DAFENC010000186
VERSION     DAFENC010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1236
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.guided.155"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            27..1181
                     /locus_tag="LP493_003091"
     CDS             27..1181
                     /locus_tag="LP493_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBL2135152.1"
                     /translation="MVIKFKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT          403 a          226 c          275 g          332 t
ORIGIN      
        1 gaaatatata aaaacggtat ggggggttgg ttataaaatt taaaaataaa aaaaacgact
       61 attccaaact agaacgaaaa ctttacatgt atatcgttgc aattgttgtg gtagcaattg
      121 tattcgtgtt gtatattcgt tcaatgatcc gagggaaact tggggattgg atcttaagta
      181 ttttggaaaa caaatatgac ttaaatcacc tggacgcgat gaaattatat caatattcca
      241 tacggaacaa tatagatatc tttatttatg tggcgattgt cattagtatt cttattctat
      301 gtcgcgtcat gctttcaaaa ttcgcaaaat actttgacga gataaatacc ggcattgatg
      361 tacttattca gaacgaagat aaacaaattg agctttctgc ggaaatggat gttatggaac
      421 aaaagctcaa cacattaaaa cggactctgg aaaagcgaga gcaggatgca aagctggccg
      481 aacaaagaaa aaatgacgtt gttatgtact tggcgcacga tattaaaacg ccccttacat
      541 ccattatcgg ttatttgagc ctgcttgacg aggctccaga catgccggta gatcaaaagg
      601 caaagtatgt gcatatcacg ttggacaaag cgtatcgact cgaacagcta atcgacgagt
      661 tttttgagat tacacggtat aacctacaaa cgataacgct aacaaaaacg cacatagacc
      721 tatactatat gctggtgcag atgaccgatg aattttatcc tcagctttcc gcacatggaa
      781 aacaggcggt tattcacgcc cccgaggatc tgaccgtgtc cggcgaccct gataaactcg
      841 cgagagtctt taacaacatt ttgaaaaacg ccgctgcata cagtgaggat aacagcatca
      901 ttgacattac cgcgggcctc tccggggatg tggtgtcaat cgaattcaag aacactggaa
      961 gcatcccaaa agataagcta gctgccatat ttgaaaagtt ctataggctg gacaatgctc
     1021 gttcttccga tacgggtggc gcgggacttg gattggcgat tgcaaaagaa attattgttc
     1081 agcatggagg gcagatttac gcggaaagca atgataacta tacgacgttt agggtagagc
     1141 ttccagcgat gccagacttg gttgataaaa ggaggtccta agagatgtat ataattttgg
     1201 ctctttgtca aatgatgttg gtaaagagaa atctta
//
LOCUS       DAFENC010000187         1093 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.guided.161, whole genome shotgun sequence.
ACCESSION   DAFENC010000187
VERSION     DAFENC010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1093
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.guided.161"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..152
                     /locus_tag="LP493_003092"
     CDS             <1..152
                     /locus_tag="LP493_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2135153.1"
                     /translation="YLIVDLKLCNRTNYAVKLYKEGNMTVNQICEITNVSRASLYRKL
                     SEVNN"
     gene            366..1061
                     /gene="vanR"
                     /locus_tag="LP493_003093"
     CDS             366..1061
                     /gene="vanR"
                     /locus_tag="LP493_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBL2135154.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
BASE COUNT          397 a          192 c          214 g          290 t
ORIGIN      
        1 cttatttgat agtagattta aaactttgca acagaaccaa ttatgcggta aagctatata
       61 aagaaggaaa tatgactgta aatcaaattt gtgaaattac taatgtatct agggcttcat
      121 tatacaggaa attatcagaa gtgaataatt agccattctg tattccgcta atgggcaata
      181 tttttaaaga agaaaaggaa actataaaat attaacagcc tcctagcgat gccgaaaagc
      241 cctttgataa aaaaagaatc atcatcttaa gaaattctta gtcatttatt atgtaaatgc
      301 ttataaattc ggccctataa tctgataaat tattaagggc aaacttatgt gaaagggtga
      361 taactatgag cgataaaata cttattgtgg atgatgaaca tgaaattgcc gatttggttg
      421 aattatactt aaaaaacgag aattatacgg ttttcaaata ctataccgcc aaagaagcat
      481 tggaatgtat agacaagtct gagattgacc ttgccatatt ggacatcatg cttcccggca
      541 caagcggcct tactatctgt caaaaaataa gggacaagca cacctatccg attatcatgc
      601 tgaccgggaa agatacagag gtagataaaa ttacagggtt aacaatcggc gcggatgatt
      661 atataacgaa gccctttcgc ccactggagt taattgctcg ggtaaaggcc cagttgcgcc
      721 gatacaaaaa attcagtgga gtaaaggagc agaacgaaaa tgttatcgtc cactccggcc
      781 ttgtcattaa tgttaacacc catgagtgtt atctgaacga gaagcagtta tcccttactc
      841 ccaccgagtt ttcaatactg cgaatcctct gtgaaaacaa ggggaatgtg gttagctccg
      901 agctgctatt tcatgagata tggggcgacg aatatttcag caagagcaac aacaccatca
      961 ccgtgcatat ccggcatttg cgcgaaaaaa tgaacgacac cattgataat ccgaaatata
     1021 taaaaacggt atggggggtt ggttataaaa ttgaaaaata aaaaaaacga ctattccaaa
     1081 ctagaacgaa aac
//
LOCUS       DAFENC010000188         1093 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.guided.162, whole genome shotgun sequence.
ACCESSION   DAFENC010000188
VERSION     DAFENC010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1093
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.guided.162"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            <1..152
                     /locus_tag="LP493_003094"
     CDS             <1..152
                     /locus_tag="LP493_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBL2135155.1"
                     /translation="YLIVDLKLCNRTNYAVKLYKEGNMTVNQICEITNVSRASLYRKL
                     SEVNN"
     gene            366..1055
                     /gene="vanR"
                     /locus_tag="LP493_003095"
     CDS             366..1055
                     /gene="vanR"
                     /locus_tag="LP493_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBL2135156.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKI"
BASE COUNT          397 a          192 c          213 g          291 t
ORIGIN      
        1 cttatttgat agtagattta aaactttgca acagaaccaa ttatgcggta aagctatata
       61 aagaaggaaa tatgactgta aatcaaattt gtgaaattac taatgtatct agggcttcat
      121 tatacaggaa attatcagaa gtgaataatt agccattctg tattccgcta atgggcaata
      181 tttttaaaga agaaaaggaa actataaaat attaacagcc tcctagcgat gccgaaaagc
      241 cctttgataa aaaaagaatc atcatcttaa gaaattctta gtcatttatt atgtaaatgc
      301 ttataaattc ggccctataa tctgataaat tattaagggc aaacttatgt gaaagggtga
      361 taactatgag cgataaaata cttattgtgg atgatgaaca tgaaattgcc gatttggttg
      421 aattatactt aaaaaacgag aattatacgg ttttcaaata ctataccgcc aaagaagcat
      481 tggaatgtat agacaagtct gagattgacc ttgccatatt ggacatcatg cttcccggca
      541 caagcggcct tactatctgt caaaaaataa gggacaagca cacctatccg attatcatgc
      601 tgaccgggaa agatacagag gtagataaaa ttacagggtt aacaatcggc gcggatgatt
      661 atataacgaa gccctttcgc ccactggagt taattgctcg ggtaaaggcc cagttgcgcc
      721 gatacaaaaa attcagtgga gtaaaggagc agaacgaaaa tgttatcgtc cactccggcc
      781 ttgtcattaa tgttaacacc catgagtgtt atctgaacga gaagcagtta tcccttactc
      841 ccaccgagtt ttcaatactg cgaatcctct gtgaaaacaa ggggaatgtg gttagctccg
      901 agctgctatt tcatgagata tggggcgacg aatatttcag caagagcaac aacaccatca
      961 ccgtgcatat ccggcatttg cgcgaaaaaa tgaacgacac cattgataat ccgaaatata
     1021 taaaaacggt atggggggtt ggttataaaa tttaaaaata aaaaaaacga ctattccaaa
     1081 ctagaacgaa aac
//
LOCUS       DAFENC010000189          772 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.guided.180, whole genome shotgun sequence.
ACCESSION   DAFENC010000189
VERSION     DAFENC010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..772
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.guided.180"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            18..755
                     /gene="erm(B)"
                     /locus_tag="LP493_003096"
     CDS             18..755
                     /gene="erm(B)"
                     /locus_tag="LP493_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBL2135157.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT          287 a          138 c          120 g          227 t
ORIGIN      
        1 acttcaggag tgattacatg aacaaaaata taaaatattc tcaaaacttt ttaacgagtg
       61 aaaaagtact caaccaaata ataaaacaat tgaatttaaa agaaaccgat accgtttacg
      121 aaattggaac aggtaaaggg catttaacga cgaaactggc taaaataagt aaacaggtaa
      181 cgtctattga attagacagt catctattca acttatcgtc agaaaaatta aaactgaaca
      241 ctcgtgtcac tttaattcac caagatattc tacagtttca attccctaac aaacagaggt
      301 ataaaattgt tgggaatatt ccttaccatt taagcacaca aattattaaa aaagtggttt
      361 ttgaaagcca tgcgtctgac atctatctga ttgttgaaga aggattctac aagcgtacct
      421 tggatattca ccgaacacta gggttgctct tgcacactca agtctcgatt cagcaattgc
      481 ttaagctgcc agcggaatgc tttcatccta aaccaaaagt aaacagtgtc ttaataaaac
      541 ttacccgcca taccacagat gttccagata aatattggaa gctatatacg tactttgttt
      601 caaaatgggt caatcgagaa tatcgtcaac tgtttactaa aaatcagttt catcaagcaa
      661 tgaaacacgc caaagtaaac aatttaagta ccgttactta tgagcaagta ttgtctattt
      721 ttaatagtta tctattattt aacgggagga aataattcta tgagtcgctt tt
//
LOCUS       DAFENC010000190          772 bp    DNA     linear   BCT 22-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate PR18325_1
            SAMN20572093-rid13346323.guided.181, whole genome shotgun sequence.
ACCESSION   DAFENC010000190
VERSION     DAFENC010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN20572093
            Sequence Read Archive: SRR16917263
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-NOV-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 17-NOV-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001176986.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001176986.1
            Genome Coverage       :: 70x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/17/2021 09:32:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,097
            CDSs (total)                      :: 3,040
            Genes (coding)                    :: 2,971
            CDSs (with protein)               :: 2,971
            Genes (RNA)                       :: 57
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 30 of 69
            Pseudo Genes (incomplete)         :: 35 of 69
            Pseudo Genes (internal stop)      :: 14 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..772
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN20572093-rid13346323.guided.181"
                     /isolate="PR18325_1"
                     /isolation_source="Perirectal Swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Ann Arbor, Michigan"
                     /lat_lon="42.285 N 83.73 W"
                     /collection_date="2017-09"
                     /collected_by="University of Michigan"
     gene            18..755
                     /gene="erm(B)"
                     /locus_tag="LP493_003097"
     CDS             18..755
                     /gene="erm(B)"
                     /locus_tag="LP493_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBL2135158.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT          286 a          137 c          121 g          228 t
ORIGIN      
        1 acttcaggag tgattacatg aacaaaaata taaaatattc tcaaaacttt ttaacgagtg
       61 aaaaagtact caaccaaata ataaaacaat tgaatttaaa agaaaccgat accgtttacg
      121 aaattggaac aggtaaaggg catttaacga cgaaactggc taaaataagt aaacaggtaa
      181 cgtctattga attagacagt catctattca acttatcgtc agaaaaatta aaactgaaca
      241 ttcgtgtcac tttaattcac caagatattc tacagtttca attccctaac aaacagaggt
      301 ataaaattgt tgggagtatt ccttaccatt taagcacaca aattattaaa aaagtggttt
      361 ttgaaagcca tgcgtctgac atctatctga ttgttgaaga aggattctac aagcgtacct
      421 tggatattca ccgaacacta gggttgctct tgcacactca agtctcgatt cagcaattgc
      481 ttaagctgcc agcggaatgc tttcatccta aaccaaaagt aaacagtgtc ttaataaaac
      541 ttacccgcca taccacagat gttccagata aatattggaa gctatatacg tactttgttt
      601 caaaatgggt caatcgagaa tatcgtcaac tgtttactaa aaatcagttt catcaagcaa
      661 tgaaacacgc caaagtaaac aatttaagta ccgttactta tgagcaagta ttgtctattt
      721 ttaatagtta tctattattt aacgggagga aataattcta tgagtcgctt tt
//
